# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase PF00069.20 KND85066.1 - 0.00033 19.8 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HNH_2 PF13391.1 KND85078.1 - 4.3e-12 45.6 0.0 7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 KND85219.1 - 6.4e-16 58.2 0.0 3.3e-15 55.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND85219.1 - 1.2e-10 40.9 0.0 2.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND85219.1 - 0.00066 18.8 0.0 0.00091 18.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KND85219.1 - 0.077 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KND85299.1 - 0.00011 22.0 1.1 0.00031 20.5 0.8 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family NACHT PF05729.7 KND85546.1 - 3.5e-12 46.2 0.4 1.8e-11 43.9 0.3 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND85546.1 - 5.6e-08 32.9 0.2 8.5e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND85546.1 - 0.00018 21.6 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KND85546.1 - 0.0002 20.3 0.0 0.00027 19.8 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 KND85546.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MFS_1 PF07690.11 KND85565.1 - 3.7e-05 22.5 37.0 0.0019 17.0 25.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.4 KND85565.1 - 3.2 7.8 8.3 0.25 11.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Pkinase PF00069.20 KND85605.1 - 4.7e-22 78.3 0.0 6.2e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND85605.1 - 0.0019 17.3 0.0 0.0049 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3435 PF11917.3 KND85610.1 - 1.8e-93 313.5 0.0 4.1e-93 312.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Pkinase PF00069.20 KND85730.1 - 5.3e-08 32.3 0.0 8.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KND85730.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND85730.1 - 0.02 14.2 0.0 0.09 12.0 0.0 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KND85730.1 - 0.067 12.2 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KND85730.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Borealin PF10512.4 KND85791.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 CALCOCO1 PF07888.6 KND85791.1 - 0.07 11.4 0.8 0.076 11.3 0.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4437 PF14499.1 KND85791.1 - 0.14 11.0 0.1 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) MFS_1 PF07690.11 KND85793.1 - 5.9e-12 44.9 19.6 5.9e-12 44.9 13.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cytochrom_B558a PF05038.8 KND85793.1 - 0.072 12.7 2.1 0.41 10.2 0.0 2.7 3 0 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit NAD_binding_6 PF08030.7 KND85816.1 - 8.8e-09 35.4 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DEAD PF00270.24 KND85829.1 - 2.3e-33 115.0 0.0 4e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND85829.1 - 3.9e-23 81.1 0.0 1.6e-21 75.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND85829.1 - 6.2e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DDE_1 PF03184.14 KND85843.1 - 5.4e-18 64.9 0.0 1.7e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease Arc PF03869.9 KND85912.1 - 0.014 15.0 0.1 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Arc-like DNA binding domain Nol1_Nop2_Fmu PF01189.12 KND85973.1 - 1.6e-16 60.5 0.0 1.3e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family TMV_coat PF00721.16 KND85973.1 - 0.048 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Virus coat protein (TMV like) Mito_carr PF00153.22 KND85974.1 - 3.4e-55 183.7 3.6 3.5e-23 81.1 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2370 PF10176.4 KND85978.1 - 1.3e-81 273.4 0.4 2.2e-81 272.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF605 PF04652.11 KND85978.1 - 2.7 7.2 13.7 4.2 6.6 9.5 1.2 1 0 0 1 1 1 0 Vta1 like PCMT PF01135.14 KND86008.1 - 4e-49 166.9 0.0 5.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KND86008.1 - 0.00033 21.2 0.0 0.00059 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86008.1 - 0.00043 19.9 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86008.1 - 0.0009 19.2 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KND86008.1 - 0.014 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4013 PF13197.1 KND86058.1 - 0.016 14.5 1.4 0.023 14.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) UCH PF00443.24 KND86081.1 - 4.1e-54 183.4 0.1 4.1e-54 183.4 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND86081.1 - 3.3e-27 95.6 1.7 2.2e-23 83.1 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Borrelia_P83 PF05262.6 KND86081.1 - 1.8 6.7 23.2 3.9 5.6 16.1 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein Polyketide_cyc PF03364.15 KND86105.1 - 5e-19 68.5 0.0 6.3e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KND86105.1 - 7.1e-05 22.9 0.4 9.6e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF45 PF01863.12 KND86106.1 - 0.12 12.1 5.1 0.17 11.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 APH PF01636.18 KND86108.1 - 6.4e-11 42.4 0.6 8.1e-10 38.8 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86108.1 - 2.3e-05 24.0 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DNA_pol_A_exo1 PF01612.15 KND86109.1 - 7.5e-07 28.7 0.0 8.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DUF4066 PF13278.1 KND86111.1 - 5.6e-19 68.0 0.1 2.9e-17 62.4 0.0 2.0 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KND86111.1 - 4.4e-08 32.6 0.1 6.6e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family BMC PF00936.14 KND86111.1 - 0.045 13.4 0.1 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 BMC domain SLAC1 PF03595.12 KND86112.1 - 8.3e-22 77.2 4.2 1e-21 76.9 2.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel AzlC PF03591.9 KND86112.1 - 0.051 13.5 0.4 0.071 13.0 0.3 1.1 1 0 0 1 1 1 0 AzlC protein DUF2332 PF10094.4 KND86113.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) DUF1517 PF07466.6 KND86113.1 - 0.1 11.5 7.5 0.15 10.9 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RAP1 PF07218.6 KND86113.1 - 1.5 6.8 9.1 1.8 6.5 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 KND86114.1 - 6.9e-20 71.2 0.0 9.3e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86114.1 - 2.1e-17 63.0 0.0 2.7e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND86114.1 - 2.3e-07 30.0 0.0 3.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND86114.1 - 8e-05 21.8 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND86114.1 - 0.0058 16.3 0.2 0.019 14.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86114.1 - 0.045 13.3 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 KND86114.1 - 0.16 10.7 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KND86114.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF3328 PF11807.3 KND86115.1 - 1.8e-51 174.8 1.4 2.4e-51 174.4 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) APH PF01636.18 KND86116.1 - 3.1e-05 23.8 0.0 5.9e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86116.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KND86117.1 - 5.5e-10 38.8 0.0 5.2e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86117.1 - 3.4e-07 29.6 0.0 5e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND86117.1 - 0.0011 18.7 0.7 0.064 12.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KND86117.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 KND86117.1 - 0.018 14.6 0.0 0.48 9.9 0.0 2.4 2 1 1 3 3 3 0 Choline/ethanolamine kinase DOG1 PF14144.1 KND86117.1 - 0.14 12.2 0.1 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Seed dormancy control Fer2_3 PF13085.1 KND86119.1 - 1.4e-31 108.5 0.0 1.9e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 KND86119.1 - 0.00057 19.5 0.2 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.4 KND86119.1 - 1.6 8.3 4.2 3.1 7.3 2.9 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B adh_short_C2 PF13561.1 KND86120.1 - 2.3e-21 76.6 0.2 2.9e-21 76.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND86120.1 - 3.2e-20 72.7 1.3 4.8e-20 72.1 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND86120.1 - 9.5e-11 41.6 0.4 1.4e-10 41.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND86120.1 - 0.012 14.5 0.1 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KND86120.1 - 0.089 12.7 1.6 2 8.3 1.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding Flu_PB1 PF00602.12 KND86120.1 - 0.12 10.1 0.0 0.16 9.7 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Methyltransf_PK PF05891.7 KND86122.1 - 4.2e-40 137.3 0.0 5.1e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DUF2726 PF10881.3 KND86122.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) F-box PF00646.28 KND86123.1 - 3.5e-05 23.3 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain DPM3 PF08285.6 KND86123.1 - 0.024 14.4 0.1 0.05 13.4 0.0 1.6 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) APH PF01636.18 KND86124.1 - 2.1e-11 44.0 0.0 8.4e-11 42.0 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family ACBP PF00887.14 KND86127.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Acyl CoA binding protein Kinesin PF00225.18 KND86133.1 - 9.5e-55 185.6 0.0 2.6e-54 184.2 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain Herpes_BLRF2 PF05812.7 KND86133.1 - 0.0032 17.2 1.7 0.023 14.4 0.1 2.6 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein bZIP_2 PF07716.10 KND86133.1 - 0.16 11.7 2.1 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Cep57_CLD_2 PF14197.1 KND86133.1 - 0.67 9.9 7.9 1.4 8.8 0.2 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Ank_2 PF12796.2 KND86134.1 - 1.1e-43 147.4 0.0 1.5e-14 54.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND86134.1 - 6.2e-43 142.5 0.0 4.2e-07 29.4 0.0 7.5 6 1 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KND86134.1 - 1.5e-31 108.2 0.0 2.5e-10 40.5 0.0 5.1 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86134.1 - 5.2e-24 81.9 0.0 0.00065 19.6 0.0 7.6 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KND86134.1 - 4.1e-22 77.7 0.0 8e-06 25.9 0.0 5.0 3 1 3 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.7 KND86134.1 - 0.00038 20.1 0.0 0.00087 18.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain GATase_6 PF13522.1 KND86134.1 - 0.045 13.7 0.0 1 9.2 0.0 2.8 2 1 1 3 3 3 0 Glutamine amidotransferase domain p450 PF00067.17 KND86135.1 - 9.2e-58 195.8 0.0 1.2e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_60s PF00428.14 KND86136.1 - 0.083 13.2 11.2 0.22 11.9 5.6 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.20 KND86139.1 - 3.3e-09 36.2 0.0 1.4e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KND86139.1 - 0.0034 16.4 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KND86139.1 - 0.0037 16.3 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND86139.1 - 0.0069 16.1 0.2 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 KND86139.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PDE8 PF08629.5 KND86140.1 - 0.11 12.2 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 PDE8 phosphodiesterase Pkinase PF00069.20 KND86141.1 - 3.4e-15 55.8 0.0 2.4e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KND86141.1 - 5.4e-13 49.2 0.9 4.6e-06 26.5 0.1 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86141.1 - 3.6e-06 26.7 0.0 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KND86141.1 - 9.5e-06 24.8 0.0 0.00045 19.3 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KND86141.1 - 1.6e-05 24.0 0.0 0.0004 19.5 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND86141.1 - 6.2e-05 22.4 0.0 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.6 KND86141.1 - 0.00016 20.4 0.0 0.00024 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 KND86141.1 - 0.096 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Lipase_3 PF01764.20 KND86143.1 - 2.2e-32 111.6 0.0 3.1e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KND86143.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KND86143.1 - 0.0021 18.3 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KND86143.1 - 0.0023 17.7 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KND86143.1 - 0.0096 15.3 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KND86143.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold SelB-wing_1 PF09105.5 KND86144.1 - 0.14 11.8 0.7 0.31 10.7 0.5 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix TUG-UBL1 PF11470.3 KND86146.1 - 1.8e-24 85.4 0.1 3.1e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 KND86146.1 - 0.0047 16.6 0.2 0.017 14.8 0.1 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain DUF4294 PF14127.1 KND86146.1 - 0.0089 15.6 0.6 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4294) PAT1 PF09770.4 KND86146.1 - 0.43 8.7 13.0 0.7 8.0 9.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.10 KND86146.1 - 3.7 6.7 5.6 5.5 6.1 3.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Proteasome PF00227.21 KND86147.1 - 7e-40 136.3 0.0 8.4e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.15 KND86148.1 - 1.1e-60 204.5 6.6 1.5e-59 200.8 4.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND86148.1 - 3.1e-45 153.9 3.7 3.1e-45 153.9 2.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND86148.1 - 3.2e-27 96.3 0.0 3.5e-26 92.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND86148.1 - 1.2e-22 79.6 0.0 2.4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KND86148.1 - 1.4e-18 66.1 0.1 3.1e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KND86148.1 - 3.1e-12 47.0 0.0 1.4e-11 44.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND86148.1 - 4.4e-07 29.7 1.6 5.2e-06 26.2 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND86148.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KND86149.1 - 3.3e-45 153.9 8.6 6.1e-45 153.0 6.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND86149.1 - 3e-25 89.9 0.1 5.5e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND86149.1 - 9.5e-14 52.0 0.0 1.8e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND86149.1 - 2.4e-08 33.8 0.2 3.3e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase YjeF_N PF03853.10 KND86149.1 - 0.00017 21.2 1.2 0.73 9.4 0.1 3.3 2 1 1 3 3 3 2 YjeF-related protein N-terminus HMA PF00403.21 KND86149.1 - 0.00029 20.9 0.2 0.00096 19.2 0.1 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Lig_chan PF00060.21 KND86149.1 - 0.16 11.7 0.8 0.4 10.3 0.6 1.8 1 0 0 1 1 1 0 Ligand-gated ion channel S6PP PF05116.8 KND86149.1 - 0.16 11.2 0.1 27 3.9 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase SNARE PF05739.14 KND86150.1 - 1.3e-18 66.3 3.0 9.4e-18 63.6 0.2 2.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KND86150.1 - 7.9e-17 61.3 0.9 7.9e-17 61.3 0.6 2.9 4 1 0 4 4 4 1 Syntaxin MCPsignal PF00015.16 KND86150.1 - 0.0027 17.2 0.5 0.0027 17.2 0.3 2.6 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 KND86150.1 - 0.021 14.2 0.0 0.052 12.9 0.0 1.7 1 0 0 1 1 1 0 Integral membrane protein Sed5p E2R135 PF11570.3 KND86150.1 - 0.052 13.6 2.1 2.6 8.1 0.0 2.5 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 NPV_P10 PF05531.7 KND86150.1 - 0.15 12.2 4.2 24 5.2 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 KND86150.1 - 0.33 9.8 8.3 1.4 7.7 0.2 3.0 2 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KND86150.1 - 0.37 9.4 6.8 0.11 11.1 1.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein LTXXQ PF07813.7 KND86150.1 - 8.1 6.9 10.6 5 7.6 0.4 3.4 3 1 0 3 3 3 0 LTXXQ motif family protein Aldo_ket_red PF00248.16 KND86151.1 - 4.5e-48 163.4 0.0 5.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 KND86152.1 - 2.9e-26 91.3 2.0 3.1e-26 91.2 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND86152.1 - 3.4e-15 55.7 0.9 6.1e-15 54.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YdfZ PF14001.1 KND86152.1 - 0.028 14.6 0.7 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 YdfZ protein Pkinase PF00069.20 KND86153.1 - 7e-23 81.0 0.0 9.4e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.23 KND86153.1 - 1.3e-19 70.3 0.0 2.4e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_Tyr PF07714.12 KND86153.1 - 3.9e-14 52.3 0.0 5.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 KND86153.1 - 0.00073 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KND86153.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 PH domain TPR_10 PF13374.1 KND86154.1 - 5e-67 220.1 15.2 1.3e-11 44.0 0.0 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KND86154.1 - 1.1e-48 162.9 11.2 1.4e-15 56.9 0.1 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KND86154.1 - 5.4e-16 57.0 8.5 0.001 18.7 0.0 7.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND86154.1 - 6.4e-13 47.5 9.6 0.0032 17.2 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 KND86154.1 - 9.9e-10 37.9 1.2 7.4e-05 22.3 0.0 4.5 2 1 3 5 5 5 1 TPR repeat NB-ARC PF00931.17 KND86154.1 - 8.5e-09 34.6 0.7 0.0036 16.2 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain TPR_16 PF13432.1 KND86154.1 - 1.6e-08 35.0 1.5 0.13 12.9 0.1 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND86154.1 - 1.8e-07 30.4 3.9 1.3 8.7 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KND86154.1 - 3.2e-07 30.0 6.8 0.53 10.6 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat AAA_22 PF13401.1 KND86154.1 - 1e-06 28.9 0.0 3.2e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_4 PF07721.9 KND86154.1 - 2.6e-06 27.2 13.9 0.49 10.9 0.0 7.3 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND86154.1 - 0.00018 21.0 2.4 5.5 7.0 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KND86154.1 - 0.00021 21.3 0.2 2.1 8.5 0.0 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KND86154.1 - 0.00074 19.8 1.0 75 3.7 0.0 5.0 3 2 1 5 5 5 0 Tetratricopeptide repeat NACHT PF05729.7 KND86154.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 KND86154.1 - 0.0058 17.1 7.5 38 5.3 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat SNAP PF14938.1 KND86154.1 - 0.026 13.6 0.2 1.1 8.3 0.0 2.4 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP AAA_16 PF13191.1 KND86154.1 - 0.031 14.2 2.8 0.042 13.8 0.2 2.5 2 1 1 3 3 3 0 AAA ATPase domain TPR_6 PF13174.1 KND86154.1 - 0.031 14.7 2.7 23 5.7 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4074 PF13293.1 KND86154.1 - 0.25 11.6 2.9 45 4.3 0.1 4.3 5 1 0 5 5 3 0 Domain of unknown function (DUF4074) PPR PF01535.15 KND86154.1 - 4.5 7.4 5.7 69 3.7 0.0 4.9 6 0 0 6 6 5 0 PPR repeat HNH_2 PF13391.1 KND86155.1 - 1.2e-09 37.8 0.0 3.3e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Glyco_transf_25 PF01755.12 KND86159.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Trypsin_2 PF13365.1 KND86161.1 - 0.03 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain Choline_kinase PF01633.15 KND86162.1 - 0.00048 19.7 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KND86162.1 - 0.0015 18.3 0.1 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KND86165.1 - 0.017 14.8 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KND86166.1 - 7e-06 25.2 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND86166.1 - 0.00031 19.9 0.0 0.00055 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Radial_spoke_3 PF06098.6 KND86166.1 - 0.00052 19.1 6.4 0.00088 18.3 4.4 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 HSDR_N_2 PF13588.1 KND86166.1 - 0.002 17.9 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 KND86166.1 - 0.019 14.7 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.4 KND86166.1 - 0.11 10.8 10.4 0.42 8.8 7.8 1.4 2 0 0 2 2 2 0 Transmembrane protein Mnd1 PF03962.10 KND86166.1 - 0.71 9.5 9.2 1.1 8.8 6.4 1.3 1 0 0 1 1 1 0 Mnd1 family FemAB PF02388.11 KND86166.1 - 1.5 7.4 3.8 2.2 6.8 2.6 1.2 1 0 0 1 1 1 0 FemAB family APH PF01636.18 KND86167.1 - 4.3e-06 26.6 0.0 4.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KND86167.1 - 0.0031 16.6 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86167.1 - 0.041 12.9 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.9 KND86167.1 - 0.077 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.20 KND86168.1 - 0.077 12.1 0.0 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 KND86170.1 - 1.2e-13 51.3 0.2 6.5e-13 48.9 0.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86170.1 - 2.6e-05 23.8 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KND86170.1 - 0.0032 16.4 0.0 0.0073 15.3 0.0 1.5 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 KND86170.1 - 0.017 13.7 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.2 KND86173.1 - 2e-12 47.2 0.4 1.3e-08 35.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND86173.1 - 1.6e-09 37.0 9.7 0.00069 19.2 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KND86173.1 - 5.2e-08 33.1 1.9 3.6e-06 27.3 0.2 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND86173.1 - 2.4e-07 30.7 4.5 0.0013 18.8 0.1 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86173.1 - 9.2e-07 28.5 8.0 0.053 13.7 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeat Sin_N PF04801.8 KND86175.1 - 0.12 11.2 4.2 0.18 10.6 2.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Ank_2 PF12796.2 KND86177.1 - 1.2e-09 38.3 0.2 3.1e-06 27.4 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND86177.1 - 1.4e-08 34.0 0.0 0.0013 18.4 0.0 3.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KND86177.1 - 8.4e-07 28.6 0.3 0.014 15.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KND86177.1 - 1.5e-06 28.5 0.1 0.0088 16.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND86177.1 - 2e-05 24.6 0.8 0.038 14.2 0.0 3.0 2 1 0 3 3 3 2 Ankyrin repeats (many copies) APH PF01636.18 KND86178.1 - 0.024 14.3 0.3 0.029 14.1 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family BCS1_N PF08740.6 KND86180.1 - 6.5e-29 100.8 0.5 1e-28 100.2 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KND86180.1 - 2.5e-08 34.1 0.0 6.5e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND86180.1 - 0.00077 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KND86180.1 - 0.0026 17.6 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND86180.1 - 0.0039 18.0 0.2 0.028 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KND86180.1 - 0.018 15.2 0.0 0.51 10.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 KND86180.1 - 0.018 13.7 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KND86180.1 - 0.019 14.3 0.0 0.043 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND86180.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF3958 PF13125.1 KND86180.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) AAA_29 PF13555.1 KND86180.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KND86180.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 KND86180.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KND86181.1 - 2.2e-28 98.4 0.3 1.3e-12 47.9 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND86181.1 - 1.3e-18 65.7 0.2 1.3e-06 27.9 0.2 4.2 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KND86181.1 - 7.4e-16 58.1 0.8 1.7e-10 41.1 0.0 3.3 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND86181.1 - 9.4e-14 51.1 0.4 7.7e-05 22.8 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86181.1 - 5.2e-13 47.8 0.4 0.00081 19.4 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat DUF3716 PF12511.3 KND86182.1 - 1.3e-09 37.5 4.9 1.3e-09 37.5 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) zf-RING_6 PF14835.1 KND86182.1 - 0.23 11.2 2.3 0.44 10.3 1.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Integrin_B_tail PF07965.7 KND86182.1 - 0.63 10.4 5.9 1 9.8 4.1 1.4 1 0 0 1 1 1 0 Integrin beta tail domain DUF3435 PF11917.3 KND86183.1 - 9.7e-119 396.7 1.8 1.3e-118 396.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.1 KND86183.1 - 0.75 10.2 4.6 22 5.6 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KND86183.1 - 5 7.6 7.0 11 6.5 0.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type COesterase PF00135.23 KND86185.1 - 1.2e-93 314.6 0.0 1.6e-93 314.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KND86185.1 - 7.1e-07 29.0 0.0 3.3e-06 26.8 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND86185.1 - 0.012 14.7 0.2 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND86185.1 - 0.042 13.6 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Arylesterase PF01731.15 KND86186.1 - 0.00059 19.7 0.1 0.0015 18.4 0.1 1.8 1 1 0 1 1 1 1 Arylesterase Abi_C PF14355.1 KND86186.1 - 0.042 13.7 0.4 13 5.8 0.0 2.6 3 0 0 3 3 3 0 Abortive infection C-terminus TRP PF06011.7 KND86187.1 - 4.8e-140 467.0 29.4 5.8e-140 466.7 20.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND86187.1 - 2e-39 134.8 0.1 3.1e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.11 KND86188.1 - 2e-42 145.1 27.3 2e-42 145.1 18.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KND86188.1 - 0.001 18.8 1.7 0.0037 17.0 1.2 2.0 1 0 0 1 1 1 1 MFS_1 like family UNC-93 PF05978.11 KND86188.1 - 0.0022 17.5 8.1 0.003 17.0 0.5 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4006 PF13179.1 KND86188.1 - 0.13 11.8 0.7 4.1 7.0 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) 3HCDH PF00725.17 KND86189.1 - 5.4e-21 74.8 0.3 3e-20 72.4 0.0 2.4 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 KND86189.1 - 6e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.13 KND86189.1 - 1.4e-07 31.2 7.9 3e-07 30.2 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.7 KND86190.1 - 1.3e-21 77.0 0.1 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KND86190.1 - 0.00022 21.2 0.0 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 KND86190.1 - 0.00033 20.5 0.1 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 1 Arylesterase PDEase_II PF02112.10 KND86190.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Sugar_tr PF00083.19 KND86193.1 - 2.4e-92 309.9 21.9 9.9e-92 307.8 15.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND86193.1 - 4.1e-08 32.3 13.4 4.1e-08 32.3 9.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3154 PF11351.3 KND86193.1 - 0.061 13.0 2.4 0.49 10.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) DUF261 PF03196.8 KND86193.1 - 0.16 11.9 1.4 0.31 11.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF261 APH PF01636.18 KND86194.1 - 7.9e-17 61.7 0.0 1.1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86194.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND86194.1 - 0.13 11.6 0.0 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Lipocalin_2 PF08212.7 KND86197.1 - 0.029 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain IDO PF01231.13 KND86198.1 - 6.8e-117 390.4 0.0 8.3e-117 390.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KND86198.1 - 0.17 10.3 0.0 0.74 8.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1864) MFS_1 PF07690.11 KND86199.1 - 4.8e-28 97.8 54.3 6.6e-18 64.5 15.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND86199.1 - 2.5e-09 36.0 30.3 1.1e-08 33.9 17.7 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KND86199.1 - 0.33 10.7 6.9 0.11 12.3 1.2 2.9 3 0 0 3 3 3 0 MFS_1 like family NACHT PF05729.7 KND86202.1 - 4.9e-13 49.0 0.0 8.4e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND86202.1 - 1.2e-07 31.9 1.7 1.1e-06 28.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND86202.1 - 0.00019 21.5 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND86202.1 - 0.00082 18.8 0.3 0.0023 17.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND86202.1 - 0.004 16.8 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KND86202.1 - 0.017 15.2 0.0 0.058 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KND86202.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DDE_Tnp_1_assoc PF13808.1 KND86202.1 - 0.044 13.4 0.2 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 DDE_Tnp_1-associated AAA_30 PF13604.1 KND86202.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KND86202.1 - 0.062 13.5 0.1 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KND86202.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 KND86202.1 - 0.086 13.6 1.3 2.3 9.0 0.9 3.2 1 1 0 1 1 1 0 AAA domain DUF2095 PF09868.4 KND86202.1 - 0.13 12.0 0.0 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) DUF2075 PF09848.4 KND86202.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Methyltransf_23 PF13489.1 KND86204.1 - 5.1e-05 23.0 0.0 5.8e-05 22.8 0.0 1.2 1 1 0 1 1 1 1 Methyltransferase domain PALP PF00291.20 KND86205.1 - 2.1e-63 214.3 0.1 2.9e-63 213.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KND86205.1 - 2e-09 37.0 0.0 1e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 CBS domain Ank_2 PF12796.2 KND86206.1 - 2.6e-38 130.2 0.0 2.6e-18 66.1 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND86206.1 - 1.2e-33 113.2 1.4 7.7e-09 34.9 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 KND86206.1 - 2.1e-33 115.1 9.6 5.6e-33 113.7 6.7 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase Ank_5 PF13857.1 KND86206.1 - 4.1e-25 87.2 1.9 1e-06 28.7 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND86206.1 - 3.6e-24 84.6 0.9 2.7e-09 37.2 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86206.1 - 2.6e-21 73.5 0.6 2.7e-07 30.1 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat MRP-L51 PF10244.4 KND86206.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit Helicase_C_3 PF13625.1 KND86207.1 - 2.4e-24 85.5 0.0 3.1e-23 81.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND86207.1 - 1.1e-11 44.9 0.0 2.2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KND86207.1 - 4.1e-10 39.3 0.0 9.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KND86207.1 - 1.1e-08 34.3 0.0 1.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Peptidase_M28 PF04389.12 KND86208.1 - 7.8e-27 94.1 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KND86208.1 - 2.5e-12 46.3 0.0 5.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 PA domain HNH_2 PF13391.1 KND86209.1 - 0.00012 21.8 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DDHD PF02862.12 KND86211.1 - 0.052 13.3 3.7 0.074 12.8 2.6 1.1 1 0 0 1 1 1 0 DDHD domain ProQ PF04352.8 KND86211.1 - 0.078 12.6 0.2 0.078 12.6 0.1 2.0 1 1 0 2 2 2 0 ProQ/FINO family Ank_2 PF12796.2 KND86213.1 - 8.2e-08 32.4 0.0 8.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KND86213.1 - 7e-07 28.7 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 KND86213.1 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86213.1 - 0.0002 21.2 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 KND86213.1 - 0.045 14.2 0.0 0.081 13.4 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Pkinase PF00069.20 KND86214.1 - 2.2e-32 112.2 0.0 2.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86214.1 - 4.9e-12 45.4 0.0 5.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND86214.1 - 8.5e-06 25.6 0.0 0.008 15.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KND86214.1 - 0.0035 16.3 0.0 0.29 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF4188 PF13826.1 KND86217.1 - 0.062 13.3 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) Pilt PF15453.1 KND86217.1 - 5.1 6.6 6.7 0.61 9.7 1.1 1.9 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions Glyco_hydro_18 PF00704.23 KND86219.1 - 6.1e-13 48.9 0.0 7e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AFOR_C PF01314.13 KND86219.1 - 0.15 10.7 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Glyco_hydro_18 PF00704.23 KND86220.1 - 1e-22 81.1 0.4 9.1e-15 54.9 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 APH PF01636.18 KND86221.1 - 2.3e-19 70.0 2.6 4e-19 69.3 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86221.1 - 0.003 17.1 0.2 0.04 13.4 0.0 2.6 2 1 0 2 2 2 1 Choline/ethanolamine kinase Zn_clus PF00172.13 KND86222.1 - 1.3e-08 34.5 7.6 1.3e-08 34.5 5.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 KND86222.1 - 1.1 8.7 8.4 0.16 11.5 2.3 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Evr1_Alr PF04777.8 KND86222.1 - 3.3 7.6 6.0 0.28 11.0 0.5 1.8 2 0 0 2 2 2 0 Erv1 / Alr family Leader_CPA1 PF08252.6 KND86223.1 - 0.098 11.9 0.3 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Pyr_redox_3 PF13738.1 KND86224.1 - 4.6e-22 79.0 0.0 6.3e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND86224.1 - 1.8e-11 43.5 0.0 7.3e-07 28.4 0.0 3.2 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KND86224.1 - 1.2e-08 33.6 0.0 6.9e-08 31.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND86224.1 - 0.00046 20.1 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND86224.1 - 0.0026 17.5 0.6 2.4 7.9 0.0 3.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND86224.1 - 0.01 15.7 0.0 1.3 8.9 0.0 2.6 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND86224.1 - 0.015 14.1 0.1 0.084 11.7 0.0 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KND86224.1 - 0.025 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Mqo PF06039.10 KND86224.1 - 0.072 11.2 0.0 0.56 8.3 0.0 2.1 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Exo_endo_phos PF03372.18 KND86226.1 - 6.4e-10 39.3 0.1 9.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_3 PF07859.8 KND86227.1 - 7.9e-29 100.7 0.1 1.1e-28 100.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KND86227.1 - 1.4e-08 33.7 0.0 2.2e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KND86227.1 - 0.00011 21.9 0.3 0.00021 21.0 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND86227.1 - 0.045 12.9 0.1 2.6 7.2 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KND86227.1 - 0.099 12.0 0.0 1.4 8.3 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Methyltransf_3 PF01596.12 KND86228.1 - 6.1e-32 110.3 0.0 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 KND86228.1 - 2.4e-12 46.8 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KND86228.1 - 2.1e-11 44.6 0.0 4.5e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86228.1 - 4.3e-10 39.3 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86228.1 - 9.9e-09 35.7 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86228.1 - 3.1e-06 27.2 0.0 4.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND86228.1 - 0.00063 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND86228.1 - 0.00092 19.6 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND86228.1 - 0.0013 19.1 0.1 0.0034 17.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND86228.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase GCD14 PF08704.5 KND86228.1 - 0.0033 16.9 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Response_reg PF00072.19 KND86228.1 - 0.015 15.2 0.0 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain Ubie_methyltran PF01209.13 KND86228.1 - 0.018 14.1 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 KND86228.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KND86228.1 - 0.056 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 KND86228.1 - 0.099 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Hydantoinase_A PF01968.13 KND86229.1 - 1.6e-21 76.6 4.7 5.8e-21 74.8 2.7 2.2 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase DUF917 PF06032.7 KND86229.1 - 6.7e-05 21.5 1.4 0.00013 20.6 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) DUF917 PF06032.7 KND86230.1 - 1.4e-47 161.9 0.0 9.7e-26 90.1 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF917) FAD_binding_3 PF01494.14 KND86231.1 - 1.9e-14 53.5 5.8 2.8e-12 46.3 0.2 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KND86231.1 - 2.1e-05 24.4 0.5 5.2e-05 23.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND86231.1 - 8.2e-05 21.6 6.7 0.017 14.0 2.8 2.7 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND86231.1 - 0.005 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND86231.1 - 0.0063 15.4 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KND86231.1 - 0.018 14.1 0.3 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KND86231.1 - 0.019 14.7 2.3 0.16 11.7 1.3 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.5 KND86231.1 - 0.027 13.3 0.0 0.31 9.8 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.22 KND86231.1 - 0.031 14.6 0.3 0.083 13.3 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND86231.1 - 0.036 13.1 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KND86231.1 - 0.058 12.0 2.9 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 KND86231.1 - 0.12 10.8 0.6 0.18 10.2 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein GMC_oxred_N PF00732.14 KND86232.1 - 8.3e-57 192.5 0.0 1.5e-56 191.7 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND86232.1 - 1.6e-34 119.2 0.4 4e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND86232.1 - 4.6e-06 25.7 4.5 0.00084 18.2 0.7 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KND86232.1 - 1.1e-05 24.5 0.5 0.0046 15.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND86232.1 - 6.3e-05 22.9 1.3 0.00022 21.1 0.3 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND86232.1 - 0.00021 21.2 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND86232.1 - 0.00033 19.6 0.3 0.00057 18.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KND86232.1 - 0.0016 18.5 0.2 0.47 10.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND86232.1 - 0.0023 16.4 0.5 0.011 14.2 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KND86232.1 - 0.0092 15.0 0.1 0.02 13.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KND86232.1 - 0.017 15.5 0.2 0.16 12.3 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KND86232.1 - 0.022 14.7 0.2 0.073 13.0 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_9 PF13454.1 KND86232.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KND86232.1 - 0.16 10.5 0.1 0.26 9.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DEAD PF00270.24 KND86234.1 - 5.9e-42 143.0 0.0 9.6e-41 139.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND86234.1 - 3.3e-21 74.9 0.1 8.3e-21 73.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.9 KND86234.1 - 0.0013 18.4 0.0 0.0089 15.6 0.0 2.0 2 0 0 2 2 2 1 Helicase ResIII PF04851.10 KND86234.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KND86234.1 - 0.0062 16.2 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 KND86234.1 - 0.06 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 KND86234.1 - 0.076 12.5 0.1 0.41 10.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KND86234.1 - 0.17 12.0 0.5 0.8 9.8 0.4 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KND86234.1 - 0.2 10.6 0.0 0.43 9.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.13 KND86235.1 - 1.2e-12 47.3 4.0 2.7e-12 46.1 2.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86236.1 - 1.1e-07 31.5 12.8 2.1e-07 30.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydant_A_N PF05378.8 KND86237.1 - 2.9e-13 49.7 0.2 3.2e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region DUF760 PF05542.6 KND86237.1 - 0.003 17.6 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF760) MutL PF13941.1 KND86237.1 - 0.012 13.9 0.1 0.013 13.8 0.1 1.2 1 0 0 1 1 1 0 MutL protein Transp_cyt_pur PF02133.10 KND86238.1 - 1.1e-37 129.6 10.9 1.4e-37 129.2 7.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF202 PF02656.10 KND86238.1 - 1.9 8.7 7.6 3.1 8.0 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Cyt_c_ox_IV PF12270.3 KND86238.1 - 6.2 6.5 7.8 15 5.2 0.8 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV Sugar_tr PF00083.19 KND86239.1 - 1.1e-61 208.7 21.2 1.4e-61 208.4 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND86239.1 - 9.8e-08 31.0 42.2 0.0003 19.5 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND86239.1 - 0.00039 18.9 1.7 0.00039 18.9 1.2 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein zf-RING_3 PF14369.1 KND86240.1 - 0.029 14.3 0.5 0.057 13.4 0.4 1.5 1 0 0 1 1 1 0 zinc-finger SBF PF01758.11 KND86241.1 - 1.3e-13 50.7 8.0 2.4e-10 40.1 3.6 2.7 2 1 1 3 3 3 2 Sodium Bile acid symporter family Methyltransf_31 PF13847.1 KND86244.1 - 0.00057 19.5 0.0 0.00067 19.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 KND86245.1 - 8.2e-19 67.7 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86245.1 - 3e-05 23.2 0.1 5.4e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND86245.1 - 0.0012 17.9 0.1 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND86245.1 - 0.094 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3209 PF11483.3 KND86245.1 - 0.12 12.7 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) RRM_6 PF14259.1 KND86246.1 - 0.0038 17.1 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CBFD_NFYB_HMF PF00808.18 KND86248.1 - 2.1e-14 53.3 0.8 2.8e-14 52.9 0.2 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone APH PF01636.18 KND86254.1 - 1.7e-15 57.4 0.0 2.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND86254.1 - 0.00054 19.3 0.0 0.0035 16.7 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KND86254.1 - 0.0036 16.8 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KND86254.1 - 0.07 12.1 0.0 0.34 9.8 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 KND86254.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3867 PF12983.2 KND86255.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) Amdo_NSP PF12475.3 KND86256.1 - 0.017 15.0 0.4 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Amdovirus non-structural protein Sel1 PF08238.7 KND86257.1 - 1.8e-34 117.3 31.8 7.9e-06 26.3 0.1 8.3 7 0 0 7 7 7 7 Sel1 repeat MFS_1 PF07690.11 KND86257.1 - 1e-33 116.5 25.3 1e-33 116.5 17.5 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86257.1 - 6.8e-09 34.8 9.2 6.8e-09 34.8 6.4 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KND86257.1 - 0.031 12.4 8.9 0.0072 14.5 3.3 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OPT PF03169.10 KND86260.1 - 9.7e-177 589.1 54.4 1.1e-176 588.9 37.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3638 PF12340.3 KND86261.1 - 3.2e-99 330.5 0.3 3.2e-99 330.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KND86261.1 - 1.1e-17 62.8 0.1 2.1e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Fumble PF03630.9 KND86262.1 - 1.8e-128 428.1 0.2 1.7e-127 424.9 0.1 1.9 1 1 0 1 1 1 1 Fumble TPR_12 PF13424.1 KND86264.1 - 0.0004 20.2 0.5 1 9.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND86264.1 - 0.0038 17.7 0.3 1.1 10.0 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KND86264.1 - 0.011 15.6 0.6 0.32 10.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND86264.1 - 0.022 15.1 0.1 0.35 11.2 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND86264.1 - 0.024 15.0 0.7 0.024 15.0 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND86264.1 - 0.1 12.5 0.4 1.6 8.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND86264.1 - 0.18 11.4 0.2 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND86264.1 - 1 9.2 5.4 2.8 7.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 KND86265.1 - 1.1e-08 34.7 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KND86265.1 - 0.14 11.5 0.0 0.5 9.7 0.0 1.8 1 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KND86266.1 - 1.4e-34 119.3 36.4 1.6e-33 115.9 10.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86266.1 - 2.1e-10 39.7 9.1 2.1e-10 39.7 6.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KND86266.1 - 2.5e-05 22.8 2.9 2.5e-05 22.8 2.0 2.5 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.8 KND86266.1 - 0.021 12.9 5.9 0.039 12.0 4.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3317 PF11779.3 KND86266.1 - 0.39 10.1 4.5 0.43 10.0 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) BTB PF00651.26 KND86269.1 - 1.6e-13 50.5 0.1 2.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ORC4_C PF14629.1 KND86269.1 - 0.085 12.2 0.0 0.93 8.8 0.0 2.1 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus Methyltransf_23 PF13489.1 KND86271.1 - 2.1e-05 24.2 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86271.1 - 3.5e-05 24.3 0.0 5.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86271.1 - 0.00026 20.6 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND86271.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KND86271.1 - 0.012 14.6 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 KND86271.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KND86271.1 - 0.031 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KND86271.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 KND86271.1 - 0.15 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Cyclin_N PF00134.18 KND86273.1 - 1.9e-12 46.8 0.1 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KND86273.1 - 1.3e-05 25.6 0.9 2.3e-05 24.8 0.6 1.4 1 1 0 1 1 1 1 Cyclin DUF1752 PF08550.5 KND86274.1 - 7.5e-07 28.6 6.5 1.5e-06 27.6 4.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF676 PF05057.9 KND86275.1 - 9.3e-07 28.3 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND86275.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KND86275.1 - 6.9e-05 22.8 0.0 9.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND86275.1 - 0.0023 17.6 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KND86275.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.20 KND86276.1 - 1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND86276.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_4 PF01565.18 KND86277.1 - 7.1e-26 90.3 4.2 1.1e-25 89.7 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND86277.1 - 3e-12 46.2 0.1 7e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like TPP_enzyme_N PF02776.13 KND86278.1 - 4.1e-34 117.5 0.0 6.2e-33 113.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KND86278.1 - 9.8e-21 73.9 0.0 2.4e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KND86278.1 - 6.7e-18 64.7 0.0 2.3e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TctB PF07331.6 KND86279.1 - 0.14 11.7 6.8 0.025 14.2 2.1 1.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Nramp PF01566.13 KND86280.1 - 3.3e-88 295.8 20.2 5.8e-88 295.0 14.0 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein WD40 PF00400.27 KND86281.1 - 2.2e-38 128.7 18.0 8.2e-11 41.3 0.0 8.5 7 1 0 7 7 7 5 WD domain, G-beta repeat NACHT PF05729.7 KND86281.1 - 6.4e-21 74.7 0.0 1.2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KND86281.1 - 0.00018 21.6 0.0 0.00058 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.3 KND86281.1 - 0.00091 17.4 1.5 0.066 11.3 0.1 3.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 AAA_16 PF13191.1 KND86281.1 - 0.017 15.0 0.6 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KND86281.1 - 0.026 14.2 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2293 PF10056.4 KND86281.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) BBS2_Mid PF14783.1 KND86281.1 - 0.11 12.2 0.0 7.6 6.3 0.0 3.4 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region RNA_helicase PF00910.17 KND86281.1 - 0.12 12.6 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CPSF73-100_C PF11718.3 KND86283.1 - 0.016 14.5 0.1 0.031 13.6 0.1 1.5 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term UDPG_MGDP_dh_N PF03721.9 KND86284.1 - 1.4e-20 73.4 0.1 1.5e-18 66.8 0.1 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KND86284.1 - 2.4e-18 66.1 0.0 5.9e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 KND86284.1 - 2.2e-05 24.3 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 KND86284.1 - 0.0081 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Polysacc_deac_1 PF01522.16 KND86285.1 - 4.5e-21 74.7 0.0 6.8e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KND86285.1 - 2.8e-05 24.0 15.5 2.8e-05 24.0 10.8 4.3 4 0 0 4 4 4 3 Chitin recognition protein Chitin_synth_2 PF03142.10 KND86286.1 - 1.3e-36 126.1 3.9 2.4e-24 85.6 0.5 3.3 3 1 0 3 3 3 3 Chitin synthase Glycos_transf_2 PF00535.21 KND86286.1 - 5.1e-08 32.7 0.0 0.0032 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KND86286.1 - 7.8e-07 28.9 2.4 7.8e-07 28.9 1.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND86286.1 - 4.5e-06 26.6 0.8 0.076 12.8 0.0 3.2 3 0 0 3 3 3 3 Glycosyltransferase like family 2 Glyco_transf_6 PF03414.8 KND86286.1 - 0.0028 16.1 0.2 0.0048 15.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 6 DUF4070 PF13282.1 KND86286.1 - 0.14 11.6 0.3 0.7 9.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Pkinase PF00069.20 KND86288.1 - 1.2e-08 34.4 0.0 5.9e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86288.1 - 9.3e-07 28.1 0.0 2.3e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND86288.1 - 0.00025 20.8 0.2 0.0017 18.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KND86288.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KND86288.1 - 0.0062 16.1 0.1 0.013 15.1 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KND86288.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 KND86288.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KND86288.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ABC_tran PF00005.22 KND86291.1 - 6.4e-35 120.4 0.4 2e-25 89.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND86291.1 - 2.6e-16 59.8 6.8 4e-09 36.2 0.6 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KND86291.1 - 1.5e-10 40.7 0.1 4e-05 22.9 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND86291.1 - 1.2e-09 38.5 0.2 0.0054 16.7 0.0 3.2 2 1 1 3 3 3 2 AAA domain SbcCD_C PF13558.1 KND86291.1 - 0.00012 21.8 1.3 0.06 13.2 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KND86291.1 - 0.00036 20.0 0.3 0.00088 18.7 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KND86291.1 - 0.0007 19.1 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KND86291.1 - 0.00086 18.8 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 KND86291.1 - 0.00095 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 KND86291.1 - 0.0015 18.5 0.6 0.004 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KND86291.1 - 0.0067 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 KND86291.1 - 0.0095 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KND86291.1 - 0.011 15.3 0.1 0.28 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KND86291.1 - 0.024 14.5 0.0 0.071 13.0 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KND86291.1 - 0.044 14.1 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kua-UEV1_localn PF10520.4 KND86291.1 - 0.046 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF87 PF01935.12 KND86291.1 - 0.064 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_25 PF13481.1 KND86291.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND86291.1 - 0.066 13.3 0.1 0.4 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KND86291.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND86292.1 - 9.2e-09 35.7 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 KND86292.1 - 0.00088 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 KND86292.1 - 0.00093 18.9 0.0 0.015 15.0 0.0 2.3 3 0 0 3 3 3 1 Archaeal ATPase AAA_29 PF13555.1 KND86292.1 - 0.0095 15.4 0.1 0.028 13.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KND86292.1 - 0.012 15.6 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KND86292.1 - 0.012 14.7 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 KND86292.1 - 0.013 14.7 0.2 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 KND86292.1 - 0.013 15.3 0.3 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KND86292.1 - 0.016 15.2 0.1 0.043 13.8 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KND86292.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Adeno_IVa2 PF02456.10 KND86292.1 - 0.019 13.6 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_23 PF13476.1 KND86292.1 - 0.026 14.8 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KND86292.1 - 0.027 13.5 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KND86292.1 - 0.064 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.4 KND86292.1 - 0.065 11.7 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein MMR_HSR1 PF01926.18 KND86292.1 - 0.067 13.1 0.2 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 KND86292.1 - 0.088 12.2 0.2 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KND86292.1 - 0.13 12.7 0.3 0.42 11.1 0.1 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 KND86292.1 - 0.16 11.8 0.1 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PALP PF00291.20 KND86294.1 - 1.1e-29 103.6 0.3 1.3e-29 103.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KND86294.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 LytB protein PIF1 PF05970.9 KND86295.1 - 1.9e-08 33.6 1.5 6.2e-08 31.9 1.1 1.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KND86295.1 - 1.4e-07 31.2 0.6 2.9e-07 30.2 0.3 1.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 KND86295.1 - 2.3e-05 24.0 0.1 5.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 KND86295.1 - 0.019 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KND86295.1 - 0.045 13.4 0.3 0.17 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) P12 PF12669.2 KND86297.1 - 0.045 13.9 0.1 0.18 12.0 0.1 2.1 1 0 0 1 1 1 0 Virus attachment protein p12 family CD99L2 PF12301.3 KND86297.1 - 0.052 13.2 4.4 1.4 8.6 1.4 2.3 2 0 0 2 2 2 0 CD99 antigen like protein 2 RCR PF12273.3 KND86297.1 - 1.1 9.8 9.3 6.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Glyco_hydro_71 PF03659.9 KND86300.1 - 3.3e-58 196.9 4.8 4.8e-58 196.4 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_3 PF00933.16 KND86301.1 - 1.5e-60 204.7 0.0 2.2e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND86301.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF1212 PF06738.7 KND86301.1 - 0.092 12.2 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Abhydrolase_1 PF00561.15 KND86302.1 - 1.8e-09 37.4 0.1 3.6e-09 36.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND86302.1 - 6.5e-08 32.7 0.0 1.3e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidase PF01425.16 KND86303.1 - 9.5e-66 222.4 1.0 2.2e-64 217.9 0.2 2.1 2 0 0 2 2 2 2 Amidase Lar_restr_allev PF14354.1 KND86304.1 - 0.068 13.4 0.4 0.068 13.4 0.3 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Fungal_trans_2 PF11951.3 KND86305.1 - 6e-23 81.0 0.0 9.3e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86305.1 - 0.00052 19.8 11.2 0.00052 19.8 7.7 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATPase-cat_bd PF12156.3 KND86307.1 - 0.045 14.2 0.0 16 6.0 0.0 2.3 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase APH PF01636.18 KND86308.1 - 1.5e-08 34.6 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86308.1 - 0.0045 16.6 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KND86308.1 - 0.011 14.3 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 KND86308.1 - 0.038 13.1 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Anoctamin PF04547.7 KND86309.1 - 5.8e-99 331.7 6.2 7.6e-99 331.3 4.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel APH PF01636.18 KND86310.1 - 4.8e-06 26.4 0.0 0.0004 20.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KND86310.1 - 6.6e-05 22.0 0.0 0.00033 19.7 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KND86310.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 KND86310.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KND86310.1 - 0.0033 16.7 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KND86310.1 - 0.016 14.8 0.1 0.63 9.5 0.0 2.4 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.1 KND86310.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_18 PF00704.23 KND86311.1 - 4.4e-39 134.9 7.6 2.5e-38 132.4 5.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KND86311.1 - 6e-15 54.8 0.5 6e-08 32.4 0.0 3.8 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.14 KND86311.1 - 5.5e-06 26.2 3.2 5.5e-06 26.2 2.2 2.9 4 0 0 4 4 4 1 Chitin recognition protein Varsurf_PPLC PF03490.8 KND86311.1 - 0.059 13.0 0.3 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C DZR PF12773.2 KND86313.1 - 0.0043 16.8 4.6 0.0076 16.0 3.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KND86313.1 - 0.059 12.5 9.4 0.1 11.8 6.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KND86313.1 - 0.069 12.6 6.5 0.12 11.8 4.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF4131 PF13567.1 KND86313.1 - 0.071 12.5 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3824 PF12868.2 KND86313.1 - 0.52 11.2 14.1 1.3 9.9 9.8 1.7 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) GFA PF04828.9 KND86313.1 - 1.3 8.9 7.6 2.1 8.3 0.3 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KND86313.1 - 5.7 6.7 12.5 2.1 8.1 0.3 2.6 2 0 0 2 2 2 0 Nudix N-terminal MFS_1 PF07690.11 KND86314.1 - 8.8e-18 64.1 74.0 4.5e-14 51.9 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_3 PF01596.12 KND86315.1 - 1.1e-26 93.1 0.0 1.4e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KND86315.1 - 4.9e-12 46.6 0.1 1.5e-11 45.0 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86315.1 - 8.1e-08 32.8 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86315.1 - 1.3e-07 31.6 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND86315.1 - 0.0035 16.8 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 KND86315.1 - 0.0078 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 KND86315.1 - 0.026 14.0 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Peptidase_S49 PF01343.13 KND86315.1 - 0.032 14.0 0.0 0.07 12.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 Methyltransf_23 PF13489.1 KND86315.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KND86316.1 - 1.4e-41 142.4 53.1 3.1e-21 75.4 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86316.1 - 0.024 13.2 45.3 0.0058 15.2 14.1 3.4 2 2 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 KND86317.1 - 2.7e-39 134.9 51.4 6.6e-39 133.6 34.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 KND86317.1 - 1.1 9.5 8.8 0.2 11.8 0.4 3.9 2 1 1 3 3 3 0 PepSY-associated TM helix CUE PF02845.11 KND86318.1 - 6.5e-08 31.9 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 KND86318.1 - 0.34 10.9 0.0 0.61 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) HMD PF03201.11 KND86319.1 - 0.022 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Complex1_49kDa PF00346.14 KND86319.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ofd1_CTDD PF10637.4 KND86320.1 - 1e-102 342.8 0.0 1.2e-93 313.0 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KND86320.1 - 5.7e-16 58.8 0.0 1.4e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KND86320.1 - 0.025 14.2 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PMT PF02366.13 KND86321.1 - 5.9e-78 261.6 15.7 9e-78 261.0 10.9 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KND86321.1 - 8.2e-25 87.4 1.5 1.3e-24 86.7 0.7 1.6 1 1 0 1 1 1 1 MIR domain CAP59_mtransfer PF11735.3 KND86322.1 - 1.8e-86 289.3 0.0 2.3e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-C2H2_4 PF13894.1 KND86324.1 - 0.085 13.2 13.9 1.6 9.2 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KND86324.1 - 4.1 7.9 13.2 0.091 13.1 1.0 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KND86324.1 - 9.1 6.7 10.4 0.58 10.5 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PHD PF00628.24 KND86325.1 - 1.9e-07 30.6 9.7 3e-07 30.0 6.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KND86325.1 - 0.00038 20.1 3.1 0.00038 20.1 2.1 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KND86325.1 - 0.0072 16.0 1.2 0.0072 16.0 0.8 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 KND86325.1 - 0.039 13.2 5.1 0.022 14.0 2.1 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain SRRM_C PF15230.1 KND86325.1 - 0.098 12.7 1.7 0.3 11.2 1.2 1.8 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus FYVE_2 PF02318.11 KND86325.1 - 0.13 12.1 4.6 0.24 11.3 3.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DNA_RNApol_7kD PF03604.8 KND86325.1 - 0.41 10.1 7.3 2.7 7.5 1.4 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Asn_synthase PF00733.16 KND86327.1 - 6e-49 166.8 0.0 7.8e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KND86327.1 - 1.4e-06 28.0 0.0 8.5e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF4274 PF14096.1 KND86327.1 - 0.1 12.3 0.0 26 4.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) Lipase_GDSL PF00657.17 KND86328.1 - 3.2e-16 59.8 0.1 3.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KND86328.1 - 1.7e-14 54.3 0.0 2.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KND86328.1 - 6.6e-06 25.9 0.0 9.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2817 PF10994.3 KND86328.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) TFIIB PF00382.14 KND86329.1 - 6.7e-34 115.5 0.4 9e-20 70.2 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KND86329.1 - 2.4e-12 45.9 3.5 4.3e-11 41.9 2.3 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 KND86329.1 - 0.027 14.0 0.8 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain HTH_Tnp_ISL3 PF13542.1 KND86329.1 - 0.038 13.1 0.0 0.39 9.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RB_B PF01857.15 KND86329.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Glycos_transf_3 PF00591.16 KND86330.1 - 2.6e-61 207.2 0.0 4.8e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KND86330.1 - 5.8e-12 45.0 0.2 3e-11 42.7 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Herpes_gE PF02480.11 KND86331.1 - 0.006 14.9 0.1 0.0094 14.2 0.0 1.4 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Ldr_toxin PF13940.1 KND86331.1 - 0.068 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system MLANA PF14991.1 KND86331.1 - 0.078 12.9 0.1 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein melan-A Phosducin PF02114.11 KND86331.1 - 0.18 10.5 0.2 3.5 6.2 0.1 2.0 1 1 1 2 2 2 0 Phosducin CoA_transf_3 PF02515.12 KND86332.1 - 3.8e-59 199.1 0.0 5.6e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Hydrolase PF00702.21 KND86333.1 - 1.3e-15 58.3 0.2 4.1e-12 46.9 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND86333.1 - 1.3e-13 51.5 0.0 5e-12 46.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KND86333.1 - 9.2e-13 47.7 0.0 1.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KND86333.1 - 1.2e-06 28.3 0.0 3.8e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND86333.1 - 0.029 13.9 0.1 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4254 PF14063.1 KND86333.1 - 0.03 13.9 0.1 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Hydrolase_6 PF13344.1 KND86333.1 - 0.093 12.6 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Asparaginase PF00710.15 KND86334.1 - 4.5e-66 222.8 0.0 5.2e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Methyltransf_16 PF10294.4 KND86335.1 - 1.4e-45 154.8 0.0 1.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KND86335.1 - 0.00041 19.9 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86335.1 - 0.0033 17.9 0.0 0.0049 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND86335.1 - 0.0046 16.3 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KND86335.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KND86335.1 - 0.024 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Peptidase_M24 PF00557.19 KND86336.1 - 2e-45 154.9 0.0 3e-45 154.3 0.0 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KND86336.1 - 0.33 10.1 2.4 0.4 9.8 1.6 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal AA_permease PF00324.16 KND86337.1 - 3.3e-57 193.8 12.6 4.1e-57 193.5 8.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND86337.1 - 6.4e-19 67.7 12.0 8.7e-19 67.3 8.3 1.2 1 0 0 1 1 1 1 Amino acid permease YibE_F PF07907.6 KND86337.1 - 0.69 9.0 9.5 2 7.5 0.4 2.5 1 1 1 2 2 2 0 YibE/F-like protein AhpC-TSA_2 PF13911.1 KND86338.1 - 2.2e-18 66.2 0.0 8.9e-18 64.2 0.0 2.0 3 0 0 3 3 3 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KND86338.1 - 5.2e-05 22.9 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND86338.1 - 9.8e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Redoxin HSCB_C PF07743.8 KND86341.1 - 0.02 15.3 0.3 0.065 13.7 0.0 1.8 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Matrix PF00661.16 KND86341.1 - 0.074 11.3 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein Amastin PF07344.6 KND86342.1 - 0.86 9.1 4.4 0.64 9.6 0.2 2.4 3 0 0 3 3 3 0 Amastin surface glycoprotein Aldo_ket_red PF00248.16 KND86343.1 - 7.7e-50 169.2 0.0 9e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ThiF PF00899.16 KND86344.1 - 5.3e-29 100.7 0.0 8.1e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KND86344.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PIG-F PF06699.6 KND86345.1 - 2.3e-44 151.6 4.0 3.3e-44 151.1 2.8 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.1 KND86345.1 - 0.41 10.1 4.3 1.2 8.6 3.0 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KND86345.1 - 1.9 8.1 10.0 0.19 11.3 3.3 1.9 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.4 KND86345.1 - 2.1 8.5 7.9 1.9 8.6 1.3 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 KND86345.1 - 2.5 7.8 9.7 1.3 8.7 4.2 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Pmp3 PF01679.12 KND86346.1 - 5.9e-21 73.9 6.9 8.2e-21 73.4 4.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SNF2_N PF00176.18 KND86347.1 - 2.8e-52 177.3 0.1 4.7e-52 176.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KND86347.1 - 3.3e-25 87.7 0.4 3.3e-25 87.7 0.3 2.0 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KND86347.1 - 7e-14 51.4 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND86347.1 - 0.00029 20.7 0.3 0.0076 16.1 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KND86348.1 - 2.3e-52 177.6 0.1 3.9e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KND86348.1 - 2.9e-25 87.9 0.4 2.9e-25 87.9 0.3 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KND86348.1 - 6e-14 51.6 0.0 1.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND86348.1 - 0.00018 21.3 0.2 0.0065 16.3 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND86348.1 - 0.00057 19.4 0.0 0.0017 17.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Methyltransf_23 PF13489.1 KND86349.1 - 9.9e-12 44.8 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND86349.1 - 7.2e-07 29.6 0.0 2.9e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86349.1 - 8.8e-07 29.4 0.0 2.9e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND86349.1 - 8.6e-06 26.1 0.0 2.6e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86349.1 - 4.6e-05 23.4 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND86349.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KND86349.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KND86349.1 - 0.05 12.5 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 KND86349.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ribosomal_S4 PF00163.14 KND86350.1 - 2.2e-13 50.3 2.0 3.9e-13 49.5 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KND86350.1 - 8.4e-12 44.3 0.0 2.6e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 S4 domain THDPS_N_2 PF14805.1 KND86350.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PPR_3 PF13812.1 KND86351.1 - 4.8e-08 32.6 0.6 0.0063 16.7 0.0 5.5 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KND86351.1 - 6.3e-05 22.8 0.0 11 6.0 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 KND86351.1 - 0.08 12.9 6.3 2.6 8.2 0.0 4.8 6 0 0 6 6 6 0 PPR repeat Ribosomal_S18 PF01084.15 KND86352.1 - 1.1e-09 37.9 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.1 KND86353.1 - 1.3e-08 34.6 0.0 0.0065 16.4 0.0 3.1 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 KND86353.1 - 0.03 14.6 1.7 3.7 8.0 0.0 4.7 6 0 0 6 6 6 0 Pentatricopeptide repeat domain He_PIG PF05345.7 KND86354.1 - 5.4e-12 45.5 13.6 0.00079 19.4 0.0 4.7 4 0 0 4 4 4 3 Putative Ig domain TMEM154 PF15102.1 KND86354.1 - 1.1e-05 25.1 0.5 2.5e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 KND86354.1 - 0.00042 19.8 0.0 0.00091 18.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Endomucin PF07010.7 KND86354.1 - 0.0037 16.6 2.2 0.0037 16.6 1.5 1.8 2 0 0 2 2 2 1 Endomucin DUF912 PF06024.7 KND86354.1 - 0.008 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4126 PF13548.1 KND86354.1 - 0.034 13.5 0.5 0.075 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Herpes_gE PF02480.11 KND86354.1 - 0.15 10.3 0.1 0.27 9.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RELT PF12606.3 KND86354.1 - 7.5 5.7 6.7 14 4.8 4.6 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 PP2C PF00481.16 KND86355.1 - 1.7e-78 263.5 0.0 2.8e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KND86355.1 - 0.025 14.3 0.0 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KND86355.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C DHDPS PF00701.17 KND86356.1 - 2.4e-26 92.0 0.0 3.2e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GHMP_kinases_N PF00288.21 KND86357.1 - 2.8e-09 36.8 0.0 1e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND86357.1 - 7.7e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal CFEM PF05730.6 KND86358.1 - 3.5e-10 39.5 6.7 6e-10 38.8 4.6 1.4 1 0 0 1 1 1 1 CFEM domain 4HBT_2 PF13279.1 KND86359.1 - 6e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily EamA PF00892.15 KND86361.1 - 1.8e-12 47.4 26.5 3e-06 27.2 1.9 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KND86361.1 - 7.4e-06 26.1 21.2 1.5e-05 25.1 1.2 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 KND86361.1 - 0.0044 16.6 20.6 0.026 14.1 8.2 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KND86361.1 - 0.064 12.3 0.0 0.064 12.3 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF1673 PF07895.6 KND86361.1 - 0.14 11.6 2.8 0.23 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Cerato-platanin PF07249.7 KND86362.1 - 3.3e-51 172.2 0.3 3.9e-51 172.0 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin WD40 PF00400.27 KND86365.1 - 7e-28 95.4 9.5 1.7e-07 30.8 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat dCMP_cyt_deam_1 PF00383.17 KND86366.1 - 6.4e-25 86.7 1.8 9.7e-25 86.1 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KND86366.1 - 1.3e-05 25.9 0.0 0.00027 21.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND86366.1 - 2.6e-05 24.5 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain CoaE PF01121.15 KND86366.1 - 0.0032 16.8 0.1 0.0071 15.7 0.0 1.5 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_33 PF13671.1 KND86366.1 - 0.034 14.0 0.4 0.18 11.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 KND86367.1 - 6.1e-42 143.5 0.0 4.9e-41 140.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86367.1 - 3.7e-22 78.6 0.0 5.8e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DAO PF01266.19 KND86368.1 - 7e-59 199.5 0.7 8.7e-59 199.2 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND86368.1 - 4.2e-06 26.9 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND86368.1 - 6.8e-06 25.1 0.2 1.2e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND86368.1 - 2e-05 24.5 0.1 6.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KND86368.1 - 0.00013 21.2 0.3 0.00022 20.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND86368.1 - 0.00029 19.4 0.9 0.023 13.1 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 KND86368.1 - 0.00032 19.9 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND86368.1 - 0.00033 20.5 0.0 0.00075 19.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND86368.1 - 0.00035 19.7 0.1 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KND86368.1 - 0.036 13.8 1.1 5.6 6.7 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KND86368.1 - 0.056 13.8 0.3 0.22 11.9 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KND86368.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 KND86368.1 - 0.062 12.3 0.6 7.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KND86368.1 - 0.23 10.3 0.3 0.32 9.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Kelch_3 PF13415.1 KND86370.1 - 8e-26 89.5 25.8 4.4e-08 33.0 0.4 8.7 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KND86370.1 - 3.8e-21 74.5 12.7 1e-05 25.2 0.1 7.8 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KND86370.1 - 6.9e-20 70.3 0.1 3.7e-08 33.2 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KND86370.1 - 3.1e-16 58.9 6.8 1.5e-06 28.0 0.0 7.5 8 0 0 8 8 8 2 Kelch motif Kelch_1 PF01344.20 KND86370.1 - 3.6e-14 52.0 0.6 3.8e-06 26.3 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 KND86370.1 - 1e-13 50.4 7.9 3.9e-06 26.4 0.3 5.9 6 1 0 6 6 6 3 Kelch motif 2Fe-2S_thioredx PF01257.14 KND86371.1 - 4e-58 195.1 0.0 4.8e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SBP_bac_7 PF03480.8 KND86371.1 - 0.15 11.1 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 CorA PF01544.13 KND86372.1 - 0.00034 19.7 2.6 0.00092 18.3 1.8 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Srv PF10323.4 KND86372.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv PspB PF06667.7 KND86372.1 - 0.35 10.8 2.3 5.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Phage shock protein B DUF1712 PF08217.6 KND86373.1 - 1.1e-13 50.3 0.0 2.3e-12 45.9 0.0 2.5 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) MIP-T3 PF10243.4 KND86373.1 - 0.02 13.3 7.3 0.037 12.5 5.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2360 PF10152.4 KND86373.1 - 1.4 9.2 6.2 0.76 10.0 0.1 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Rifin_STEVOR PF02009.11 KND86374.1 - 0.026 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF1517 PF07466.6 KND86374.1 - 0.062 12.2 0.2 0.098 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF2062 PF09835.4 KND86374.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) SKG6 PF08693.5 KND86374.1 - 0.15 11.3 6.5 0.32 10.3 4.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DPBB_1 PF03330.13 KND86375.1 - 0.0029 17.5 0.6 0.0047 16.8 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 KND86375.1 - 0.12 11.7 31.2 0.14 11.4 21.6 1.1 1 0 0 1 1 1 0 Vta1 like ABC_membrane PF00664.18 KND86377.1 - 1.6e-70 237.6 38.6 6.1e-37 127.5 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND86377.1 - 3.8e-59 198.8 0.1 6.2e-29 101.0 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND86377.1 - 3.8e-14 52.4 8.4 1.1e-06 28.0 1.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND86377.1 - 1.3e-11 45.0 0.1 0.043 13.7 0.2 4.3 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 KND86377.1 - 2.8e-09 37.2 0.2 0.00043 20.3 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 KND86377.1 - 9.9e-09 34.2 0.2 0.03 12.8 0.0 3.5 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KND86377.1 - 1.4e-07 30.9 1.5 0.00025 20.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KND86377.1 - 2e-07 30.3 0.1 0.005 16.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND86377.1 - 4.9e-07 29.9 1.2 0.079 13.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KND86377.1 - 1.8e-06 28.7 0.2 0.022 15.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND86377.1 - 1.6e-05 24.4 2.4 0.057 12.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KND86377.1 - 3.8e-05 23.3 1.1 0.39 10.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.1 KND86377.1 - 7.5e-05 22.6 0.3 0.22 11.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.1 KND86377.1 - 0.00012 21.9 1.9 0.52 10.2 0.1 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KND86377.1 - 0.00013 21.1 0.1 0.014 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.20 KND86377.1 - 0.00016 21.2 0.5 0.37 10.2 0.1 3.1 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 KND86377.1 - 0.00024 21.2 4.3 2.2 8.4 0.1 4.6 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KND86377.1 - 0.00028 21.1 0.1 1 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KND86377.1 - 0.00033 21.0 4.2 0.032 14.5 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND86377.1 - 0.00056 19.6 0.1 0.099 12.4 0.0 3.6 3 0 0 3 3 2 1 Part of AAA domain DUF3987 PF13148.1 KND86377.1 - 0.001 17.6 0.0 0.0027 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_33 PF13671.1 KND86377.1 - 0.0032 17.3 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND86377.1 - 0.0064 16.2 0.2 7.2 6.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KND86377.1 - 0.012 15.3 0.3 0.83 9.3 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KND86377.1 - 0.018 14.5 0.6 0.29 10.5 0.0 3.0 4 0 0 4 4 3 0 AAA-like domain AAA_28 PF13521.1 KND86377.1 - 0.02 14.8 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KND86377.1 - 0.037 13.1 0.8 4.7 6.2 0.0 3.0 4 0 0 4 4 3 0 Zeta toxin Miro PF08477.8 KND86377.1 - 0.039 14.4 0.3 15 6.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 KND86377.1 - 0.043 12.6 0.1 1.8 7.3 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain PRK PF00485.13 KND86377.1 - 0.063 12.8 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 KND86377.1 - 0.064 12.9 0.1 15 5.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KND86377.1 - 0.14 11.7 0.6 17 4.9 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase PP-binding PF00550.20 KND86378.1 - 1.5e-11 44.3 0.2 2.5e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KND86378.1 - 3.3e-06 27.0 0.7 6.1e-06 26.1 0.5 1.5 1 1 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.19 KND86379.1 - 7.2e-07 28.7 9.8 9.5e-06 25.1 1.4 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KND86379.1 - 0.6 10.1 17.7 0.25 11.4 0.6 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_M14 PF00246.19 KND86380.1 - 2.1e-35 122.7 0.1 3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fer4 PF00037.22 KND86381.1 - 2.6e-13 48.9 16.5 7.8e-08 31.6 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KND86381.1 - 7.6e-12 45.4 10.6 1.9e-11 44.1 7.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KND86381.1 - 1.9e-09 38.1 7.2 0.00034 21.2 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 KND86381.1 - 2.1e-09 37.5 9.5 4.4e-09 36.4 6.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KND86381.1 - 6.8e-09 35.3 21.9 1e-07 31.6 8.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 KND86381.1 - 2.4e-08 33.7 31.3 1.4e-05 24.7 8.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KND86381.1 - 2.1e-07 30.4 14.7 0.00063 19.5 1.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KND86381.1 - 3.7e-07 29.7 17.1 0.0018 18.0 3.6 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 KND86381.1 - 5.2e-07 29.6 20.8 4.2e-05 23.4 8.2 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.1 KND86381.1 - 2.2e-05 24.6 10.3 0.0014 18.8 7.8 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 KND86381.1 - 0.00027 21.0 18.1 0.00083 19.4 2.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KND86381.1 - 0.00029 21.2 13.3 0.0079 16.5 0.6 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KND86381.1 - 0.012 15.9 14.8 0.43 11.0 3.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 KND86381.1 - 0.033 14.7 14.5 0.32 11.6 1.1 3.5 3 1 0 3 3 3 0 4Fe-4S single cluster domain DUF834 PF05754.9 KND86381.1 - 0.046 13.5 0.8 0.14 12.0 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Fer4_3 PF12798.2 KND86381.1 - 0.098 13.2 16.9 0.23 12.1 2.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KND86381.1 - 0.17 12.0 4.5 0.28 11.3 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Ank_2 PF12796.2 KND86383.1 - 6.2e-22 77.7 0.0 9.6e-10 38.6 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND86383.1 - 1.4e-17 62.5 1.4 1.2e-05 24.8 0.0 6.0 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KND86383.1 - 9.4e-17 60.6 4.9 1.7e-09 37.6 0.3 5.4 3 3 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86383.1 - 1.7e-16 58.6 0.2 0.0063 16.6 0.0 7.1 7 1 1 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 KND86383.1 - 2.2e-13 50.3 0.3 7.3e-06 26.3 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Fungal_trans PF04082.13 KND86384.1 - 1.2e-19 70.1 0.1 2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86384.1 - 1e-09 38.1 10.1 2.2e-09 37.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2b PF00587.20 KND86385.1 - 1.2e-64 217.0 0.0 1.9e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND86385.1 - 1.1e-20 73.3 0.0 6.9e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Fructosamin_kin PF03881.9 KND86389.1 - 3.3e-23 82.0 0.4 4.1e-23 81.7 0.3 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KND86390.1 - 2e-10 40.8 0.3 2.9e-10 40.2 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86390.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KND86390.1 - 0.021 13.9 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DUF3632 PF12311.3 KND86391.1 - 3.6e-39 134.4 0.2 4.5e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Helicase_C_2 PF13307.1 KND86392.1 - 2e-59 200.3 0.0 4.1e-59 199.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KND86392.1 - 3e-31 108.1 0.0 5.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KND86392.1 - 0.02 14.7 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2288 PF10052.4 KND86392.1 - 0.081 12.6 0.2 0.32 10.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) SNF2_N PF00176.18 KND86392.1 - 0.12 11.1 0.1 0.41 9.4 0.0 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain Ribonuclease PF00545.15 KND86394.1 - 9.4e-05 22.4 0.8 0.00015 21.7 0.5 1.3 1 1 0 1 1 1 1 ribonuclease GRIM-19 PF06212.7 KND86395.1 - 0.0056 16.3 0.1 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein NIF PF03031.13 KND86396.1 - 3.7e-27 94.9 0.0 7.8e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 KND86396.1 - 3e-10 40.0 0.0 1.1e-09 38.3 0.0 2.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KND86396.1 - 1.2e-09 37.8 0.0 3.9e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl PF00364.17 KND86396.1 - 0.0073 15.9 0.0 4.6 6.9 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme Ribosomal_S2 PF00318.15 KND86396.1 - 0.03 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 Glypican PF01153.14 KND86396.1 - 1.1 7.7 4.2 2.1 6.8 2.9 1.4 1 0 0 1 1 1 0 Glypican Cnd1_N PF12922.2 KND86397.1 - 7.5e-56 188.4 0.9 3.4e-55 186.2 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KND86397.1 - 3.2e-55 186.7 1.4 3e-52 177.0 0.1 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KND86397.1 - 3.2e-11 43.3 5.0 2.1e-05 24.7 0.1 5.7 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KND86397.1 - 8.3e-09 34.8 5.5 0.075 13.1 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KND86397.1 - 1.9e-05 25.0 6.1 0.079 13.4 0.0 5.6 6 0 0 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 KND86397.1 - 0.0056 16.5 0.0 0.91 9.4 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Ald_Xan_dh_C2 PF02738.13 KND86397.1 - 0.011 14.1 0.0 0.018 13.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Cohesin_HEAT PF12765.2 KND86397.1 - 0.042 13.8 0.2 14 5.8 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 KND86397.1 - 0.26 10.2 6.6 0.096 11.6 0.9 3.1 2 2 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.20 KND86398.1 - 1.8e-41 141.9 0.0 6.7e-20 71.3 0.0 3.9 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND86398.1 - 6e-16 58.2 0.0 2.3e-09 36.7 0.0 3.9 3 1 1 4 4 4 2 Protein tyrosine kinase APH PF01636.18 KND86398.1 - 0.00032 20.5 5.9 0.013 15.2 3.6 3.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND86398.1 - 0.0012 17.8 0.0 0.027 13.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SDA1 PF05285.7 KND86398.1 - 0.077 12.2 19.1 0.12 11.6 13.2 1.2 1 0 0 1 1 1 0 SDA1 DUF605 PF04652.11 KND86398.1 - 0.082 12.2 11.3 0.15 11.3 7.9 1.3 1 0 0 1 1 1 0 Vta1 like SAPS PF04499.10 KND86398.1 - 0.27 9.8 4.8 0.38 9.3 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pex14_N PF04695.8 KND86398.1 - 1.9 8.5 7.8 0.18 11.8 0.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.5 KND86398.1 - 7 6.1 22.6 0.3 10.5 0.8 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Ribosomal_L18e PF00828.14 KND86399.1 - 4.9e-34 117.4 0.1 6.8e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Transp_cyt_pur PF02133.10 KND86400.1 - 6.5e-34 117.2 30.3 1.6e-33 115.9 21.0 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin bZIP_1 PF00170.16 KND86400.1 - 6.6e-08 32.4 4.6 6.6e-08 32.4 3.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KND86400.1 - 2.2e-05 24.1 8.8 5.1e-05 23.0 6.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF2517 PF10725.4 KND86400.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Pkinase PF00069.20 KND86401.1 - 3.4e-19 69.0 0.0 1e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86401.1 - 2.2e-12 46.6 0.0 9.7e-12 44.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND86401.1 - 4.8e-05 22.5 0.0 7.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND86401.1 - 0.07 12.0 0.0 0.15 10.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF3632 PF12311.3 KND86402.1 - 6.6e-19 68.4 0.0 1.3e-18 67.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) V-set PF07686.12 KND86403.1 - 0.025 14.4 1.1 8.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin V-set domain Glyco_hydro_114 PF03537.8 KND86404.1 - 9.2e-26 89.4 0.1 1.5e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF3693 PF12472.3 KND86404.1 - 0.0042 16.6 0.6 0.009 15.5 0.4 1.5 1 0 0 1 1 1 1 Phage related protein DUF2275 PF10039.4 KND86404.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Gln-synt_C PF00120.19 KND86405.1 - 1.7e-48 165.0 0.0 4.2e-48 163.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KND86405.1 - 4.4e-25 88.7 0.0 8.2e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_49 PF03718.8 KND86406.1 - 5.3e-181 602.6 15.9 6.6e-181 602.3 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 NAD_binding_4 PF07993.7 KND86407.1 - 2.6e-28 98.5 0.0 4.1e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KND86407.1 - 2.9e-24 85.2 0.0 2.1e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KND86407.1 - 1.6e-12 47.3 0.0 2.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KND86407.1 - 1.7e-05 24.9 0.1 5.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 KND86407.1 - 0.012 14.5 0.0 0.044 12.6 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 KND86407.1 - 0.055 13.3 0.1 0.2 11.5 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KND86407.1 - 0.2 10.5 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 KND86408.1 - 8.8e-12 44.3 7.8 1.6e-11 43.5 5.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86408.1 - 4.8e-07 28.7 0.4 4.8e-07 28.7 0.3 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Helitron_like_N PF14214.1 KND86411.1 - 1.5e-16 60.6 0.2 2.5e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3819 PF12842.2 KND86412.1 - 0.00025 20.7 0.3 0.0033 17.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) APH PF01636.18 KND86414.1 - 7.7e-15 55.2 0.0 1.5e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86414.1 - 0.0002 20.9 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND86414.1 - 0.0031 16.8 0.1 0.53 9.6 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.20 KND86414.1 - 0.011 14.8 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain HSP20 PF00011.16 KND86415.1 - 4.8e-16 58.4 0.0 4.1e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4432 PF14486.1 KND86415.1 - 0.04 12.4 0.0 0.062 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) NYN PF01936.13 KND86417.1 - 1.1e-30 106.7 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 KND86417.1 - 1.1e-14 53.9 0.0 1.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Dynamin_N PF00350.18 KND86418.1 - 7.4e-32 110.4 0.0 1.6e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND86418.1 - 6e-15 54.8 0.0 1.8e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KND86418.1 - 0.00062 19.6 0.1 0.021 14.7 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KND86418.1 - 0.073 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein GED PF02212.13 KND86418.1 - 0.088 12.7 1.1 0.42 10.5 0.2 2.7 2 1 0 2 2 2 0 Dynamin GTPase effector domain Pyr_redox_3 PF13738.1 KND86419.1 - 1.7e-22 80.5 0.0 3.6e-21 76.1 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND86419.1 - 5.7e-12 45.2 0.8 9.6e-09 34.5 0.0 3.4 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KND86419.1 - 1.3e-11 44.0 0.0 7.2e-05 21.8 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.14 KND86419.1 - 9.6e-09 33.9 0.7 1.9e-07 29.6 0.2 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND86419.1 - 1e-08 35.0 0.0 2.9e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND86419.1 - 1.3e-06 28.4 0.0 0.0025 17.6 0.0 2.7 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND86419.1 - 6.4e-06 26.0 0.0 0.0071 16.1 0.0 3.2 3 1 0 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.12 KND86419.1 - 0.0035 16.4 0.0 0.032 13.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KND86419.1 - 0.015 14.2 0.0 0.08 11.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KND86419.1 - 0.028 13.4 0.0 0.086 11.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KND86419.1 - 0.055 11.9 0.0 0.39 9.1 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 KND86419.1 - 0.061 12.1 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 KND86419.1 - 0.081 13.0 0.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KND86421.1 - 2.6e-29 102.2 0.4 5.3e-29 101.2 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND86421.1 - 8.5e-27 94.4 0.1 1.8e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.13 KND86421.1 - 2.2e-08 33.8 9.8 4.1e-08 33.0 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KR PF08659.5 KND86421.1 - 6.1e-08 32.5 0.4 2.7e-07 30.4 0.2 2.0 1 1 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.3 KND86421.1 - 3.3e-07 29.2 0.2 9.4e-07 27.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Eno-Rase_NADH_b PF12242.3 KND86421.1 - 0.0058 16.3 0.4 0.048 13.4 0.2 2.5 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pkinase PF00069.20 KND86423.1 - 4.4e-11 42.4 0.0 7.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86423.1 - 1.6e-05 24.1 0.1 3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND86423.1 - 0.00079 18.4 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KND86423.1 - 0.0058 15.5 0.1 0.011 14.5 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KND86423.1 - 0.013 14.5 0.4 0.028 13.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND86423.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BCS1_N PF08740.6 KND86426.1 - 3.5e-52 176.7 0.2 3.5e-52 176.7 0.1 2.2 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KND86426.1 - 3.3e-17 62.9 0.0 3e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND86426.1 - 0.00029 20.8 0.0 0.00079 19.4 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 KND86426.1 - 0.00082 19.1 0.0 0.0073 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KND86426.1 - 0.00086 18.7 0.2 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND86426.1 - 0.0066 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KND86426.1 - 0.019 15.7 2.4 0.035 14.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.7 KND86426.1 - 0.024 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 KND86426.1 - 0.026 13.6 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.1 KND86426.1 - 0.058 13.2 1.2 0.33 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KND86426.1 - 0.11 12.0 10.9 0.94 9.0 7.6 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND86426.1 - 0.13 12.4 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase BEX PF04538.7 KND86426.1 - 1 9.5 24.3 0.23 11.6 0.2 2.7 2 0 0 2 2 2 0 Brain expressed X-linked like family RNase_H2-Ydr279 PF09468.5 KND86426.1 - 1.3 8.1 10.8 2.5 7.2 7.5 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CobT PF06213.7 KND86426.1 - 2.2 7.3 26.2 0.037 13.1 12.3 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT FAM60A PF15396.1 KND86426.1 - 2.8 7.6 13.0 8.1 6.1 9.0 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 KND86426.1 - 5.1 4.6 14.3 9.1 3.8 9.9 1.4 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 KND86426.1 - 5.6 6.6 11.6 14 5.4 8.0 1.7 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 KND86426.1 - 7.6 5.9 8.6 14 5.1 6.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDRGK PF09756.4 KND86426.1 - 8.5 5.7 33.1 28 4.0 0.0 3.2 3 0 0 3 3 3 0 DDRGK domain AA_permease_2 PF13520.1 KND86427.1 - 4.6e-66 223.1 39.4 5.7e-66 222.8 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND86427.1 - 3.3e-19 68.5 30.8 3.3e-19 68.5 21.4 2.1 1 1 0 2 2 2 1 Amino acid permease TauD PF02668.11 KND86428.1 - 3.1e-30 105.7 0.0 4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family APH PF01636.18 KND86429.1 - 3.6e-22 79.2 0.0 4.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND86429.1 - 0.0017 17.7 0.0 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 KND86429.1 - 0.003 16.5 0.1 0.39 9.6 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase Choline_kinase PF01633.15 KND86429.1 - 0.0056 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Abhydrolase_6 PF12697.2 KND86430.1 - 7.2e-14 52.2 0.1 1.9e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND86430.1 - 5.9e-13 48.7 0.0 9.3e-12 44.9 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KND86430.1 - 1.6e-06 27.9 0.0 4.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 KND86430.1 - 1.5e-05 23.7 0.0 2.1e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 KND86430.1 - 5.3e-05 22.5 0.0 0.0006 19.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KND86430.1 - 0.0013 18.0 0.0 0.0065 15.7 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KND86430.1 - 0.004 16.6 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KND86430.1 - 0.02 13.4 0.0 0.039 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KND86430.1 - 0.032 13.7 0.0 0.059 12.9 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KND86430.1 - 0.033 13.7 0.0 11 5.5 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KND86431.1 - 7.6e-41 139.9 0.0 3.6e-40 137.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KND86431.1 - 0.0011 17.7 0.0 0.017 13.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KND86431.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_4 PF01565.18 KND86432.1 - 6.2e-14 51.6 0.0 1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HMG_CoA_synt_C PF08540.5 KND86433.1 - 3.8e-104 348.1 0.9 4.7e-104 347.8 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KND86433.1 - 9.4e-93 308.5 0.1 1.4e-92 307.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TIL PF01826.12 KND86434.1 - 0.0015 18.6 11.4 0.0015 18.6 7.9 2.2 3 0 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Pex14_N PF04695.8 KND86435.1 - 6.4e-30 103.9 0.0 6.4e-30 103.9 0.0 3.1 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF848 PF05852.6 KND86435.1 - 1e-05 25.3 2.7 0.00012 21.9 2.9 1.8 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) zf-C4H2 PF10146.4 KND86435.1 - 6.5e-05 23.0 2.2 0.00016 21.8 1.5 1.6 1 0 0 1 1 1 1 Zinc finger-containing protein IncA PF04156.9 KND86435.1 - 0.00012 21.7 0.6 0.00018 21.1 0.4 1.2 1 0 0 1 1 1 1 IncA protein HLH PF00010.21 KND86435.1 - 0.00016 21.3 3.8 0.98 9.1 0.1 3.3 1 1 2 3 3 3 1 Helix-loop-helix DNA-binding domain ERM PF00769.14 KND86435.1 - 0.00033 20.2 3.3 0.00052 19.6 2.3 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_13 PF13166.1 KND86435.1 - 0.01 14.3 1.3 0.015 13.8 0.9 1.1 1 0 0 1 1 1 0 AAA domain Use1 PF09753.4 KND86435.1 - 0.028 13.8 6.2 0.32 10.4 4.0 2.3 2 1 0 2 2 2 0 Membrane fusion protein Use1 DUF3584 PF12128.3 KND86435.1 - 0.041 11.2 11.3 0.054 10.8 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TSC22 PF01166.13 KND86435.1 - 0.075 12.9 3.2 0.62 10.0 0.2 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.7 KND86435.1 - 0.083 12.7 8.2 0.32 10.8 5.4 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 KND86435.1 - 0.45 8.0 3.0 0.6 7.5 2.1 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.4 KND86435.1 - 0.56 8.9 8.1 0.89 8.2 5.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mnd1 PF03962.10 KND86435.1 - 0.92 9.1 7.1 1.4 8.5 4.9 1.2 1 0 0 1 1 1 0 Mnd1 family Spectrin PF00435.16 KND86435.1 - 1.2 9.4 9.4 4.5 7.6 5.1 2.2 1 1 0 1 1 1 0 Spectrin repeat Spc7 PF08317.6 KND86435.1 - 1.9 7.0 9.3 2.7 6.5 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KND86435.1 - 2.2 8.2 4.4 1.3 8.9 0.1 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KND86435.1 - 3.4 8.0 5.4 6.8 7.0 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PXA PF02194.10 KND86436.1 - 1.6e-51 174.5 0.6 5.9e-51 172.6 0.0 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KND86436.1 - 5.5e-29 100.5 1.4 9.9e-29 99.7 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KND86436.1 - 4.6e-20 71.5 1.6 1.3e-19 70.0 0.5 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.14 KND86436.1 - 1.8e-12 47.3 0.2 5.1e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain bZIP_1 PF00170.16 KND86437.1 - 0.001 19.0 4.1 0.0016 18.3 2.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND86437.1 - 0.02 14.7 3.9 0.031 14.0 2.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper GST_N_3 PF13417.1 KND86438.1 - 1.3e-08 34.8 0.0 3.6e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND86438.1 - 6.4e-08 32.4 0.0 1.9e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KND86438.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KND86438.1 - 4.2e-06 26.6 0.0 1.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND86438.1 - 8e-06 25.6 0.3 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND86438.1 - 0.03 14.7 0.0 0.062 13.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_4 PF02390.12 KND86439.1 - 1.7e-51 174.0 0.0 2.1e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KND86439.1 - 0.00017 22.1 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86439.1 - 0.00042 20.3 0.0 0.00075 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KND86439.1 - 0.0046 15.9 0.1 0.035 13.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 KND86439.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KND86439.1 - 0.024 15.1 0.0 0.069 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KND86439.1 - 0.026 14.8 0.1 0.066 13.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KND86439.1 - 0.049 14.1 0.0 0.36 11.3 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KND86439.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.17 KND86443.1 - 9.3e-23 79.6 0.0 2.7e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND86443.1 - 1.6e-17 63.2 0.0 4e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND86443.1 - 2.7e-12 46.3 0.0 3.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEX11 PF05648.9 KND86444.1 - 7.1e-68 228.1 0.0 8.1e-68 228.0 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FBPase PF00316.15 KND86445.1 - 1.1e-119 399.0 0.0 1.2e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase CIA30 PF08547.7 KND86446.1 - 1e-33 116.4 0.0 1.4e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Homoserine_dh PF00742.14 KND86447.1 - 8.4e-53 178.6 0.0 1.1e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KND86447.1 - 1.1e-18 67.6 0.0 1.9e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 KND86448.1 - 4.2e-29 100.5 15.0 4.2e-29 100.5 10.4 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) DUF4557 PF15101.1 KND86448.1 - 0.2 11.4 15.1 0.22 11.3 4.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4557) GLTSCR1 PF15249.1 KND86448.1 - 8.7 6.4 14.9 0.35 10.9 0.3 3.3 3 0 0 3 3 3 0 Glioma tumor suppressor candidate region NHL PF01436.16 KND86449.1 - 5.5e-06 26.0 0.7 0.017 15.0 0.0 3.8 3 1 1 4 4 4 2 NHL repeat SGL PF08450.7 KND86449.1 - 7.6e-05 22.1 0.2 0.042 13.2 0.0 2.7 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region GSDH PF07995.6 KND86449.1 - 0.00041 19.5 3.7 0.0097 15.0 1.8 3.4 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase PD40 PF07676.7 KND86449.1 - 0.066 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.1 KND86449.1 - 0.12 11.9 4.2 2.6 7.7 0.6 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 KND86450.1 - 4.2e-49 162.7 18.9 1.7e-11 43.5 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat NAD_binding_10 PF13460.1 KND86450.1 - 5.2e-08 33.1 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding TFIIIC_delta PF12657.2 KND86450.1 - 5.8e-07 29.3 10.4 0.073 12.7 0.0 4.3 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term Semialdhyde_dh PF01118.19 KND86450.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KND86450.1 - 0.022 13.6 0.1 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein DUF3245 PF11595.3 KND86450.1 - 0.11 12.7 1.5 9.1 6.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF318 PF03773.8 KND86452.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted permease PQQ PF01011.16 KND86452.1 - 0.061 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Pkinase PF00069.20 KND86453.1 - 3.3e-75 252.5 0.0 5.2e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86453.1 - 1.3e-39 135.8 0.0 3.9e-39 134.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KND86453.1 - 2.2e-19 68.6 0.1 3.7e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KND86453.1 - 2.3e-05 23.5 0.1 4.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND86453.1 - 0.00016 20.7 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KND86453.1 - 0.0088 15.3 0.2 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KND86453.1 - 0.023 14.0 1.0 0.058 12.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family WaaY PF06176.6 KND86453.1 - 0.091 11.9 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1604 PF07713.8 KND86454.1 - 2e-36 123.6 1.8 8e-36 121.7 1.3 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KND86454.1 - 5.3e-05 22.9 1.1 5.3e-05 22.9 0.7 2.8 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 KND86454.1 - 0.0031 17.3 0.6 0.013 15.3 0.4 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3328 PF11807.3 KND86455.1 - 3.6e-33 115.0 1.9 5.7e-33 114.4 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RAI16-like PF10257.4 KND86457.1 - 2.1e-79 267.0 1.0 3.4e-79 266.3 0.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF829 PF05705.9 KND86458.1 - 2e-54 184.8 0.0 2.3e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) bZIP_1 PF00170.16 KND86459.1 - 1.4e-11 44.1 2.1 2.2e-11 43.5 1.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND86459.1 - 6.6e-05 22.6 8.0 0.00012 21.7 5.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 KND86459.1 - 0.053 12.4 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Ank_4 PF13637.1 KND86460.1 - 1.4e-19 70.0 1.5 2.2e-07 31.1 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND86460.1 - 5e-19 68.4 0.0 2.2e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND86460.1 - 1.3e-16 59.4 1.6 3.9e-06 26.3 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.7 KND86460.1 - 4.1e-09 36.2 0.0 6.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 KND86460.1 - 3.4e-08 33.4 0.7 0.0004 20.5 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 KND86460.1 - 2.9e-07 30.6 0.1 8.1e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ank_3 PF13606.1 KND86460.1 - 3.1e-07 29.9 0.3 0.084 13.1 0.0 4.4 4 0 0 4 4 3 1 Ankyrin repeat AAA_22 PF13401.1 KND86460.1 - 1.7e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KND86460.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 KND86460.1 - 0.0018 17.2 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Spc97_Spc98 PF04130.8 KND86460.1 - 0.0022 16.4 0.2 1 7.6 0.1 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family Mg_chelatase PF01078.16 KND86460.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 KND86460.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KND86460.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 KND86460.1 - 0.18 10.8 0.0 0.39 9.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Rcd1 PF04078.8 KND86462.1 - 7.5e-131 434.7 3.5 9.7e-131 434.3 2.4 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like BAF1_ABF1 PF04684.8 KND86462.1 - 0.14 10.9 24.5 0.19 10.5 17.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 KND86462.1 - 4.6 5.3 31.9 6.1 4.9 22.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 KND86462.1 - 6.7 4.8 20.9 8.5 4.4 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 KND86462.1 - 9.2 3.8 21.7 12 3.3 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) APH PF01636.18 KND86463.1 - 9.3e-08 32.0 0.2 1.5e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KND86464.1 - 2.7e-06 27.2 0.0 4e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family ProQ PF04352.8 KND86468.1 - 0.0057 16.2 0.2 0.16 11.6 0.0 2.4 2 1 0 2 2 2 1 ProQ/FINO family DUF3375 PF11855.3 KND86468.1 - 0.012 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) THUMP PF02926.12 KND86468.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 THUMP domain RuvB_N PF05496.7 KND86469.1 - 0.0028 16.7 1.0 0.003 16.6 0.7 1.0 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_12 PF13087.1 KND86470.1 - 1.2e-41 142.2 0.0 2.1e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND86470.1 - 2.8e-14 53.2 0.0 9.7e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND86470.1 - 1.2e-08 34.5 0.0 7.6e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KND86470.1 - 6.9e-05 21.9 0.0 0.11 11.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.19 KND86470.1 - 0.00016 21.2 4.9 0.00037 20.0 3.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_16 PF13191.1 KND86470.1 - 0.0038 17.2 0.1 0.0038 17.2 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 KND86470.1 - 0.0045 16.5 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KND86470.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sugar_tr PF00083.19 KND86471.1 - 5.1e-05 22.0 4.1 5.3e-05 21.9 2.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.16 KND86471.1 - 0.092 11.5 0.6 0.11 11.3 0.4 1.0 1 0 0 1 1 1 0 POT family Ank_2 PF12796.2 KND86472.1 - 9.2e-33 112.4 0.0 4.6e-17 62.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND86472.1 - 5.2e-28 95.4 0.0 1.4e-07 30.9 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KND86472.1 - 6.3e-26 87.8 0.0 1.5e-06 27.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KND86472.1 - 1.9e-25 88.7 0.7 4.8e-10 39.6 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND86472.1 - 3.9e-14 52.3 0.0 3.8e-08 33.3 0.0 2.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) UBA PF00627.26 KND86472.1 - 0.028 14.2 0.1 48 3.9 0.0 3.9 4 0 0 4 4 4 0 UBA/TS-N domain DBD_Tnp_Mut PF03108.10 KND86472.1 - 0.045 13.3 0.0 12 5.5 0.0 3.0 2 1 1 3 3 3 0 MuDR family transposase APH PF01636.18 KND86474.1 - 2e-15 57.1 0.0 3.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KND86474.1 - 6.3e-06 25.5 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KND86474.1 - 0.00016 21.3 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KND86474.1 - 0.00041 19.0 0.0 0.0006 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 KND86474.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 KND86477.1 - 1.1e-24 87.0 0.5 8.9e-23 80.7 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86477.1 - 4.1e-07 29.3 0.2 1.4e-06 27.5 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND86477.1 - 7.9e-05 21.8 0.1 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND86477.1 - 0.009 14.9 0.1 2.1 7.2 0.0 3.1 1 1 2 3 3 3 1 Kinase-like RIO1 PF01163.17 KND86477.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KND86477.1 - 0.052 12.3 0.1 0.074 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KND86477.1 - 0.1 12.2 0.6 0.44 10.2 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family 2-Hacid_dh_C PF02826.14 KND86478.1 - 1.6e-28 99.0 0.0 1.8e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KND86478.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 KND86478.1 - 0.022 14.6 0.1 0.03 14.2 0.1 1.1 1 0 0 1 1 1 0 short chain dehydrogenase DUF243 PF03103.12 KND86478.1 - 0.025 14.6 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF243) AlaDh_PNT_C PF01262.16 KND86478.1 - 0.12 11.9 0.3 1.5 8.3 0.0 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KND86480.1 - 4.2e-11 42.1 50.5 1.4e-07 30.6 10.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 KND86481.1 - 3.9e-21 75.6 0.0 7.3e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KND86483.1 - 3.2e-67 227.0 0.0 4.2e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-1a PF01176.14 KND86485.1 - 1.1e-27 95.1 0.1 1.6e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 KND86486.1 - 1.4e-24 85.9 0.2 1.9e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KND86486.1 - 0.00018 20.9 0.2 0.00037 19.9 0.1 1.5 1 0 0 1 1 1 1 WH2 motif Glycoprotein_B PF00606.13 KND86488.1 - 0.016 13.2 2.2 0.015 13.3 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B MDFI PF15316.1 KND86488.1 - 0.08 12.9 4.7 0.077 12.9 3.0 1.2 1 1 0 1 1 1 0 MyoD family inhibitor DUF4282 PF14110.1 KND86488.1 - 5.5 7.2 6.2 6.5 7.0 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SseC PF04888.7 KND86488.1 - 6 6.0 5.9 6.4 6.0 4.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CorA PF01544.13 KND86489.1 - 1.7e-13 50.2 1.0 2.5e-13 49.7 0.7 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4254 PF14063.1 KND86490.1 - 0.052 13.1 0.2 0.092 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) zf-C2H2_4 PF13894.1 KND86492.1 - 5.1e-05 23.3 20.7 0.011 15.9 2.7 3.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KND86492.1 - 0.0023 18.1 3.0 0.0023 18.1 2.1 3.6 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KND86492.1 - 0.052 13.7 0.6 0.052 13.7 0.4 2.6 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ERCC4 PF02732.10 KND86493.1 - 7.3e-25 87.3 0.0 1.6e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain 2OG-FeII_Oxy PF03171.15 KND86494.1 - 2.3e-14 53.4 0.0 4.2e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KND86494.1 - 0.05 14.1 1.0 0.24 11.9 0.7 1.9 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ABC_membrane PF00664.18 KND86495.1 - 5.9e-85 285.0 34.5 1.9e-43 148.8 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND86495.1 - 5e-62 208.2 0.0 9.4e-33 113.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND86495.1 - 2.4e-12 46.5 0.2 0.00087 18.5 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND86495.1 - 6.5e-12 46.0 0.1 0.00035 20.6 0.0 4.2 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 KND86495.1 - 4.7e-08 32.4 1.6 0.0005 19.5 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KND86495.1 - 1.1e-07 32.6 0.1 0.03 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND86495.1 - 1.8e-07 31.3 4.2 0.011 15.6 0.5 3.6 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KND86495.1 - 1.1e-06 27.4 1.6 0.0046 15.5 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KND86495.1 - 1.1e-06 27.8 0.0 0.038 13.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND86495.1 - 1.5e-06 28.3 0.1 0.08 13.0 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KND86495.1 - 0.00011 22.0 0.1 0.34 10.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KND86495.1 - 0.00018 21.7 1.4 0.17 12.1 0.0 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KND86495.1 - 0.00044 20.1 0.0 0.82 9.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.17 KND86495.1 - 0.00066 19.1 0.2 0.18 11.1 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 KND86495.1 - 0.00069 19.4 2.6 1.3 8.9 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KND86495.1 - 0.0016 18.2 0.0 2.7 7.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KND86495.1 - 0.0016 17.8 4.6 0.66 9.3 0.1 3.4 4 0 0 4 4 4 2 AAA domain MobB PF03205.9 KND86495.1 - 0.0017 18.0 0.6 0.53 9.9 0.0 3.5 4 0 0 4 4 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KND86495.1 - 0.0018 18.2 0.1 0.85 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KND86495.1 - 0.0061 16.4 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KND86495.1 - 0.0065 16.7 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KND86495.1 - 0.017 13.8 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 KND86495.1 - 0.017 14.5 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KND86495.1 - 0.023 14.1 5.8 4.4 6.6 0.1 3.8 3 1 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 KND86495.1 - 0.024 14.8 0.1 4.4 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase ATP-synt_ab PF00006.20 KND86495.1 - 0.024 14.1 0.0 7.9 5.9 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 KND86495.1 - 0.032 13.8 0.1 3.3 7.3 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KND86495.1 - 0.034 13.2 0.3 3.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.1 KND86495.1 - 0.046 14.0 0.2 5.6 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KND86495.1 - 0.055 13.4 0.0 8.6 6.3 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.10 KND86495.1 - 0.31 9.6 0.0 0.82 8.2 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein OPT PF03169.10 KND86496.1 - 8.3e-162 539.8 43.6 1e-161 539.5 30.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KND86496.1 - 0.14 11.9 2.6 0.45 10.3 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) PP-binding PF00550.20 KND86497.1 - 5.3e-13 49.0 0.2 1.1e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 KND86497.1 - 3.8e-06 25.9 0.0 5.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain DHDPS PF00701.17 KND86498.1 - 8.9e-65 218.1 0.0 1e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KND86498.1 - 0.004 16.3 0.0 0.0064 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF637 PF04830.8 KND86498.1 - 0.0051 16.4 0.8 0.0089 15.6 0.6 1.3 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) FMN_dh PF01070.13 KND86499.1 - 1.6e-97 326.5 0.3 5.1e-58 196.6 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 KND86499.1 - 4.6e-06 25.7 0.3 1.1e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KND86499.1 - 0.00059 18.8 0.1 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KND86499.1 - 0.0042 16.3 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KND86499.1 - 0.015 14.4 0.1 0.25 10.4 0.1 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KND86499.1 - 0.024 13.5 0.2 0.043 12.7 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Helitron_like_N PF14214.1 KND86500.1 - 4.7e-06 26.4 0.2 0.0011 18.7 0.2 3.0 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus ABC_tran PF00005.22 KND86501.1 - 4.5e-17 62.6 0.0 7.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KND86501.1 - 7.5e-06 25.3 0.0 8.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND86501.1 - 0.00039 20.4 0.0 0.002 18.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain Aa_trans PF01490.13 KND86501.1 - 0.0097 14.4 2.0 0.014 13.9 1.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC2_membrane_2 PF12679.2 KND86501.1 - 0.52 9.1 7.0 0.79 8.5 4.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Beta-lactamase PF00144.19 KND86502.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KND86502.1 - 6.1e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) RVT_1 PF00078.22 KND86503.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FA_hydroxylase PF04116.8 KND86504.1 - 3.9e-15 56.2 25.4 1.5e-14 54.3 14.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Selenoprotein_S PF06936.6 KND86504.1 - 2 7.9 3.7 8.7 5.8 0.6 2.2 1 1 1 2 2 2 0 Selenoprotein S (SelS) Aldo_ket_red PF00248.16 KND86505.1 - 4e-56 189.9 0.0 8.1e-56 188.9 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 KND86506.1 - 1.8e-67 227.8 0.0 2.1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KND86507.1 - 0 1597.7 0.2 6.1e-85 285.1 0.0 6.7 7 0 0 7 7 7 6 AMP-binding enzyme Condensation PF00668.15 KND86507.1 - 0 1041.9 0.0 2.9e-60 203.6 0.0 9.3 8 1 0 8 8 8 8 Condensation domain PP-binding PF00550.20 KND86507.1 - 2.6e-75 248.6 5.6 8.2e-13 48.4 0.0 7.4 7 0 0 7 7 6 6 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KND86507.1 - 1.1e-47 160.2 13.3 1.8e-21 76.2 0.2 5.9 6 0 0 6 6 6 3 HxxPF-repeated domain AMP-binding_C PF13193.1 KND86507.1 - 5.6e-42 142.5 18.6 5.1e-06 27.3 0.1 9.1 8 0 0 8 8 8 8 AMP-binding enzyme C-terminal domain Methyltransf_18 PF12847.2 KND86507.1 - 1.9e-14 54.1 0.0 3.4e-07 30.8 0.0 3.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KND86507.1 - 1.1e-11 44.4 0.0 6.3e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 KND86507.1 - 1.6e-11 44.4 0.0 0.0003 21.0 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KND86507.1 - 4.5e-11 42.8 0.0 0.00065 19.7 0.0 3.5 4 0 0 4 4 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 KND86507.1 - 4.4e-07 29.7 0.0 0.0065 16.1 0.0 3.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 KND86507.1 - 3.8e-06 27.2 0.0 0.034 14.6 0.0 3.3 2 0 0 2 2 2 2 Methyltransferase domain AATase PF07247.7 KND86507.1 - 0.00084 18.0 0.6 1.2 7.6 0.0 4.2 4 0 0 4 4 4 1 Alcohol acetyltransferase Methyltransf_16 PF10294.4 KND86507.1 - 0.0031 16.9 0.0 0.87 9.0 0.0 2.6 2 0 0 2 2 2 1 Putative methyltransferase Csm1 PF12539.3 KND86507.1 - 0.0034 17.8 5.9 3 8.3 0.0 5.4 6 0 0 6 6 5 1 Chromosome segregation protein Csm1/Pcs1 RrnaAD PF00398.15 KND86507.1 - 0.0088 15.0 0.0 0.85 8.5 0.0 2.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 KND86507.1 - 0.016 13.8 0.0 1.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) WRW PF10206.4 KND86507.1 - 1.6 8.8 0.0 1.1e+02 2.9 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f MIF4G PF02854.14 KND86507.1 - 1.8 7.9 0.3 14 5.0 0.1 2.2 2 0 0 2 2 2 0 MIF4G domain Cu-oxidase_2 PF07731.9 KND86508.1 - 1.1e-44 151.3 9.3 5.1e-41 139.4 1.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KND86508.1 - 7.5e-39 132.1 7.0 1.4e-37 128.0 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KND86508.1 - 9e-39 132.9 1.4 3.6e-33 114.7 0.2 3.2 3 0 0 3 3 3 2 Multicopper oxidase AlcCBM31 PF11606.3 KND86508.1 - 0.0021 17.9 1.6 35 4.4 0.0 4.1 4 0 0 4 4 4 0 Family 31 carbohydrate binding protein COX2 PF00116.15 KND86508.1 - 0.41 10.4 4.4 0.45 10.3 0.3 3.1 3 2 2 5 5 5 0 Cytochrome C oxidase subunit II, periplasmic domain FTR1 PF03239.9 KND86509.1 - 6.5e-88 294.6 9.6 7.9e-88 294.3 6.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Pkinase PF00069.20 KND86510.1 - 4.8e-11 42.3 0.0 5.2e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86510.1 - 4.1e-06 26.0 0.0 4.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF342 PF03961.8 KND86510.1 - 0.16 10.3 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ring_hydroxyl_A PF00848.14 KND86511.1 - 1.3e-38 132.7 5.4 1.4e-38 132.6 2.4 2.0 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KND86511.1 - 4.5e-14 51.7 0.0 8.6e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ribosomal_L3 PF00297.17 KND86512.1 - 0.042 13.2 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L3 p450 PF00067.17 KND86513.1 - 2.2e-24 85.8 0.0 2.2e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 KND86514.1 - 8.1e-62 209.1 0.2 1.2e-61 208.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KND86514.1 - 2.3e-55 187.2 0.1 5.9e-55 185.9 0.0 1.7 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KND86514.1 - 2.9e-17 62.4 0.0 7.1e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KND86514.1 - 0.00016 21.7 0.0 0.00036 20.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KND86514.1 - 0.00017 21.4 0.1 0.00029 20.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 KND86514.1 - 0.00049 20.4 0.1 0.014 15.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.7 KND86514.1 - 0.0016 18.3 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.13 KND86514.1 - 0.0017 18.3 0.0 0.0056 16.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 KND86514.1 - 0.0051 16.8 0.0 0.02 14.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND86514.1 - 0.0085 15.8 0.1 0.07 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND86514.1 - 0.019 14.8 0.1 0.041 13.7 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND86514.1 - 0.023 13.5 0.3 0.055 12.3 0.2 1.7 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KND86514.1 - 0.025 13.6 0.2 0.073 12.1 0.1 1.7 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KND86514.1 - 0.063 11.8 0.0 0.68 8.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 KND86514.1 - 0.077 13.0 0.1 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND86514.1 - 0.13 11.6 0.1 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 KND86514.1 - 0.14 11.0 0.1 2.1 7.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 KND86515.1 - 3e-45 154.6 0.0 4.1e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND86515.1 - 1.7e-06 27.8 0.4 0.019 14.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND86515.1 - 0.0013 18.8 0.2 0.0062 16.6 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KND86515.1 - 0.003 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KND86515.1 - 0.0046 16.9 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KND86515.1 - 0.0046 15.9 0.1 0.14 11.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KND86515.1 - 0.014 15.3 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND86515.1 - 0.037 12.6 0.1 0.95 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 KND86515.1 - 0.15 10.9 0.0 0.67 8.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_4 PF01565.18 KND86516.1 - 2.7e-22 78.7 1.7 5.1e-22 77.8 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND86516.1 - 0.0018 18.1 0.1 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like DUF814 PF05670.8 KND86521.1 - 1.5e-16 60.0 0.2 2.9e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Flavokinase PF01687.12 KND86523.1 - 2.8e-10 40.1 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase NmrA PF05368.8 KND86527.1 - 2.6e-33 115.2 0.0 3.2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND86527.1 - 1.3e-16 61.1 0.0 1.6e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND86527.1 - 5.3e-07 29.3 0.0 1.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KND86527.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KND86527.1 - 0.0017 18.3 0.1 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KND86527.1 - 0.068 12.0 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KND86527.1 - 0.088 11.4 0.0 0.43 9.2 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family APH PF01636.18 KND86531.1 - 4.2e-11 43.0 0.0 7.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KND86531.1 - 0.00034 19.3 0.0 0.00046 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 KND86533.1 - 5.3e-38 130.6 0.0 8.8e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86533.1 - 2.1e-16 59.7 0.0 2.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND86533.1 - 0.0011 18.7 0.7 0.0011 18.7 0.5 3.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND86533.1 - 0.0011 17.9 0.0 0.047 12.6 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Cyclin PF08613.6 KND86534.1 - 1.5e-37 129.3 0.0 2.2e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin PLRV_ORF5 PF01690.12 KND86534.1 - 0.0037 16.4 1.5 0.0037 16.4 1.0 2.0 2 1 0 2 2 2 1 Potato leaf roll virus readthrough protein Cyclin_N PF00134.18 KND86534.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HeLo PF14479.1 KND86536.1 - 1.4e-05 25.0 0.4 0.045 13.4 0.0 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation RINGv PF12906.2 KND86537.1 - 1.2e-16 60.4 7.4 2e-16 59.7 5.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KND86537.1 - 0.074 12.8 6.3 0.13 12.0 4.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 KND86537.1 - 0.099 12.4 3.2 0.21 11.4 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KND86537.1 - 9.2 5.9 6.8 17 5.0 4.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ACC_central PF08326.7 KND86539.1 - 2.1e-244 812.8 0.0 2.7e-244 812.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KND86539.1 - 1.6e-175 584.2 0.0 2.2e-175 583.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KND86539.1 - 1.5e-51 174.6 0.0 3.7e-51 173.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KND86539.1 - 4.3e-21 74.9 0.0 3.7e-19 68.7 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KND86539.1 - 6.2e-16 57.7 0.7 1.6e-15 56.4 0.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KND86539.1 - 7.9e-10 38.7 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KND86539.1 - 0.00064 18.5 0.0 0.0046 15.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KND86539.1 - 0.0017 17.9 0.0 0.0059 16.2 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KND86539.1 - 0.01 15.2 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KND86539.1 - 0.03 14.2 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain p450 PF00067.17 KND86540.1 - 1.9e-52 178.3 0.0 8.6e-46 156.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.14 KND86541.1 - 4.6e-20 71.9 1.3 4.9e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KND86541.1 - 0.0012 17.7 0.0 0.0099 14.7 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 KND86541.1 - 0.0019 18.1 0.1 0.014 15.4 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND86541.1 - 0.028 14.4 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND86541.1 - 0.034 14.5 0.1 0.092 13.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease PF00324.16 KND86543.1 - 5.5e-115 384.4 37.9 6.3e-115 384.2 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND86543.1 - 4.6e-23 81.4 40.5 6.1e-23 81.0 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KND86543.1 - 0.65 9.7 26.2 0.03 14.0 2.6 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) TPR_12 PF13424.1 KND86544.1 - 2.3e-92 303.0 36.0 1.6e-19 69.6 0.3 6.8 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 KND86544.1 - 1.5e-73 240.7 31.4 2.3e-10 40.0 0.0 10.3 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 KND86544.1 - 5.8e-28 94.4 22.6 0.00042 19.9 0.2 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KND86544.1 - 8.2e-24 82.1 25.3 0.0021 17.6 0.8 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KND86544.1 - 2.2e-22 78.4 20.5 2.6e-08 33.3 0.3 6.2 5 2 2 7 7 6 6 TPR repeat TPR_17 PF13431.1 KND86544.1 - 2.2e-14 52.3 8.2 0.49 10.7 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KND86544.1 - 1e-13 51.5 18.3 0.00053 20.5 0.4 6.2 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KND86544.1 - 3e-12 45.4 21.0 0.27 11.2 0.2 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.9 KND86544.1 - 1.1e-11 43.9 0.0 3 8.5 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KND86544.1 - 1.9e-09 37.5 11.2 0.0018 18.3 0.0 5.0 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KND86544.1 - 2.2e-09 37.1 23.5 2.6 8.9 0.2 8.5 6 2 1 8 8 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 KND86544.1 - 3.7e-09 35.8 0.0 1.6e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 KND86544.1 - 2.7e-08 34.0 23.4 0.097 13.0 0.1 6.8 5 2 2 7 7 7 4 Tetratricopeptide repeat NACHT PF05729.7 KND86544.1 - 3.3e-07 30.1 0.0 6.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Tcf25 PF04910.9 KND86544.1 - 4.4e-07 29.1 2.1 0.84 8.5 0.0 5.4 4 1 2 6 6 6 2 Transcriptional repressor TCF25 AAA_25 PF13481.1 KND86544.1 - 9.3e-07 28.4 0.0 3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ribosomal_S7 PF00177.16 KND86544.1 - 1.7e-06 27.7 1.2 2.9 7.4 0.0 5.7 1 1 5 6 6 6 1 Ribosomal protein S7p/S5e AAA_22 PF13401.1 KND86544.1 - 5.1e-06 26.6 0.0 5.5e-05 23.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain Rab5-bind PF09311.6 KND86544.1 - 1e-05 25.5 22.0 0.044 13.6 1.4 5.3 3 2 3 6 6 6 3 Rabaptin-like protein AAA_16 PF13191.1 KND86544.1 - 1.9e-05 24.7 1.1 6.8e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.1 KND86544.1 - 0.0004 19.9 18.8 15 5.6 0.1 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF3366 PF11846.3 KND86544.1 - 0.00071 19.5 10.6 8.4 6.2 0.0 6.2 3 2 2 6 6 6 0 Domain of unknown function (DUF3366) FTCD PF02971.9 KND86544.1 - 0.0021 17.7 1.4 1.1e+02 2.3 0.0 5.9 2 2 5 7 7 7 0 Formiminotransferase domain IstB_IS21 PF01695.12 KND86544.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3040 PF11239.3 KND86544.1 - 0.037 14.0 0.9 38 4.4 0.0 4.8 3 2 1 5 5 5 0 Protein of unknown function (DUF3040) TPR_3 PF07720.7 KND86544.1 - 3.6 7.4 16.8 21 5.0 0.1 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat APH PF01636.18 KND86545.1 - 2.3e-15 57.0 0.0 4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KND86545.1 - 0.093 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Choline_kinase PF01633.15 KND86545.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Methyltransf_18 PF12847.2 KND86546.1 - 1.1e-12 48.4 0.0 1.7e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86546.1 - 1.7e-12 47.1 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND86546.1 - 3.6e-12 46.5 0.0 6.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND86546.1 - 2.7e-08 34.1 0.0 4.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND86546.1 - 4.5e-08 32.9 0.0 6.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86546.1 - 5.2e-07 29.7 0.1 8.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND86546.1 - 2.7e-06 27.6 0.0 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND86546.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 KND86546.1 - 0.0021 17.2 0.0 0.005 16.0 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Pox_MCEL PF03291.11 KND86546.1 - 0.0024 16.8 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme CMAS PF02353.15 KND86546.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KND86546.1 - 0.0052 15.9 0.0 0.011 14.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KND86546.1 - 0.036 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KND86546.1 - 0.058 12.8 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.7 KND86546.1 - 0.13 11.5 0.1 0.37 10.1 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW FAD_binding_4 PF01565.18 KND86547.1 - 3e-38 130.4 7.5 5.5e-38 129.5 5.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND86547.1 - 8e-09 35.2 0.2 1.6e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KND86547.1 - 0.052 12.6 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Peripla_BP_4 PF13407.1 KND86547.1 - 0.061 12.6 0.1 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Periplasmic binding protein domain ABC_tran PF00005.22 KND86548.1 - 1.3e-41 142.0 0.0 1.4e-25 90.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 KND86548.1 - 2.6e-17 63.1 9.7 4.6e-12 45.9 1.8 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KND86548.1 - 1.4e-11 44.0 0.5 0.0056 15.9 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KND86548.1 - 7.7e-08 32.5 0.6 0.0095 15.9 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KND86548.1 - 1.4e-06 27.7 0.7 0.0033 16.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KND86548.1 - 2.9e-06 27.4 0.0 0.2 11.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 KND86548.1 - 9.3e-06 25.2 0.1 0.014 14.8 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 KND86548.1 - 3.4e-05 24.2 0.3 0.31 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KND86548.1 - 0.00012 21.0 0.2 0.24 10.2 0.3 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 KND86548.1 - 0.00015 20.9 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KND86548.1 - 0.00033 20.5 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 KND86548.1 - 0.00039 20.2 0.0 0.47 10.3 0.0 3.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KND86548.1 - 0.00068 19.7 0.0 0.17 12.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND86548.1 - 0.00068 19.0 0.0 1 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KND86548.1 - 0.00094 18.7 0.1 0.0059 16.0 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 KND86548.1 - 0.0029 17.4 0.5 0.0066 16.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KND86548.1 - 0.0085 15.8 3.8 2 8.2 0.0 3.7 4 0 0 4 4 3 1 Part of AAA domain AAA_33 PF13671.1 KND86548.1 - 0.01 15.7 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KND86548.1 - 0.01 15.6 0.1 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 KND86548.1 - 0.013 14.5 0.2 2 7.4 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KND86548.1 - 0.019 15.7 0.0 0.34 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KND86548.1 - 0.019 14.5 0.4 2.7 7.5 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KND86548.1 - 0.04 14.2 0.2 1.1 9.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain Miro PF08477.8 KND86548.1 - 0.1 13.1 0.1 31 5.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KND86548.1 - 0.11 11.3 0.0 7.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KND86548.1 - 0.11 12.0 0.5 19 4.8 0.0 2.8 3 0 0 3 3 2 0 NACHT domain cobW PF02492.14 KND86548.1 - 0.18 11.2 1.1 5.8 6.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KND86548.1 - 0.34 10.5 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AIG1 PF04548.11 KND86548.1 - 2.6 7.1 3.2 1.2 8.2 0.1 1.9 2 0 0 2 2 2 0 AIG1 family Chlam_OMP3 PF03503.8 KND86549.1 - 0.059 13.5 0.7 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 FAD_binding_8 PF08022.7 KND86550.1 - 8.2e-14 51.3 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KND86550.1 - 4.6e-12 46.1 14.4 4.6e-12 46.1 10.0 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KND86550.1 - 3.4e-07 30.3 0.0 4.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KND86550.1 - 2 8.6 17.4 0.087 12.9 1.5 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) OPT PF03169.10 KND86552.1 - 1.8e-153 512.2 42.5 2.1e-153 512.0 29.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1676 PF07898.8 KND86552.1 - 0.081 13.2 0.5 0.15 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF4014 PF13198.1 KND86552.1 - 0.6 10.5 0.0 0.6 10.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) NUDE_C PF04880.8 KND86554.1 - 5.3e-22 78.9 6.0 5.3e-22 78.9 4.2 4.5 3 2 0 3 3 1 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KND86554.1 - 0.0089 16.2 9.4 0.0089 16.2 6.5 3.6 2 1 2 4 4 3 1 Protein of unknown function (DUF904) WEMBL PF05701.6 KND86554.1 - 0.11 10.9 29.3 0.59 8.5 20.4 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Chibby PF14645.1 KND86554.1 - 0.24 11.3 11.5 0.32 10.9 1.3 2.6 1 1 1 2 2 2 0 Chibby family Filament PF00038.16 KND86554.1 - 0.87 8.9 30.5 7.9 5.8 20.0 2.6 2 1 0 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.15 KND86554.1 - 1.7 8.4 26.3 4.8 7.0 4.3 4.7 2 1 1 4 4 4 0 Prefoldin subunit IncA PF04156.9 KND86554.1 - 1.8 8.1 32.1 2.1 7.8 12.8 3.0 2 1 1 3 3 3 0 IncA protein FlxA PF14282.1 KND86554.1 - 1.8 8.5 19.5 1.7 8.5 2.5 3.9 2 1 1 4 4 4 0 FlxA-like protein Tropomyosin_1 PF12718.2 KND86554.1 - 2.3 8.0 34.1 4.3 7.1 14.0 3.7 2 1 1 3 3 3 0 Tropomyosin like Tho2 PF11262.3 KND86554.1 - 2.5 7.0 10.5 0.84 8.6 2.3 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF972 PF06156.8 KND86554.1 - 3.1 8.1 21.9 0.21 11.9 5.6 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KND86554.1 - 3.2 6.0 16.4 6.7 5.0 11.4 1.5 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 KND86554.1 - 3.6 7.5 24.9 0.037 14.0 2.6 3.2 1 1 1 3 3 3 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.4 KND86554.1 - 7.2 6.4 35.7 3.8 7.3 8.1 3.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 KND86554.1 - 7.4 6.0 30.6 1.9 7.9 12.5 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.6 KND86554.1 - 8.4 6.1 27.3 2 8.2 5.8 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Peptidase_S8 PF00082.17 KND86555.1 - 1.3e-44 152.4 0.0 2.8e-44 151.3 0.0 1.5 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 KND86555.1 - 3.1e-13 49.2 3.2 3.5e-13 49.0 0.4 2.4 2 0 0 2 2 2 1 PA domain DUF1034 PF06280.7 KND86555.1 - 5.7e-08 33.1 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) FlgD_ig PF13860.1 KND86555.1 - 0.0037 16.9 0.1 0.021 14.5 0.0 2.3 2 0 0 2 2 2 1 FlgD Ig-like domain BolA PF01722.13 KND86556.1 - 1.4e-14 53.8 0.0 1.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein DUF2422 PF10337.4 KND86557.1 - 5.5e-104 348.5 4.5 4e-101 339.0 1.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KND86557.1 - 1.1e-62 211.7 0.1 3.5e-60 203.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KND86557.1 - 8.5e-10 38.6 12.9 8.5e-10 38.6 8.9 3.7 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KND86557.1 - 6.2e-06 25.1 3.4 1.6e-05 23.7 2.4 1.6 1 0 0 1 1 1 1 Aluminium activated malate transporter PH_10 PF15411.1 KND86561.1 - 1.1e-44 151.2 0.0 1.9e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KND86561.1 - 2.7e-32 110.6 0.0 5.1e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 KND86561.1 - 1.3e-26 93.6 0.0 2.1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 KND86561.1 - 8.2e-08 31.8 0.0 1.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DUF1903 PF08991.5 KND86562.1 - 0.022 14.8 0.2 0.031 14.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) WD40 PF00400.27 KND86563.1 - 4.9e-34 114.9 4.7 1.6e-05 24.5 0.0 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KND86563.1 - 3.9e-13 48.8 1.3 1.1e-12 47.4 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND86563.1 - 4.9e-07 29.2 0.4 3.6e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KND86563.1 - 0.0023 16.1 0.1 0.57 8.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 KND86563.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain SmpA_OmlA PF04355.8 KND86563.1 - 0.015 14.8 0.7 0.53 9.9 0.0 3.2 3 0 0 3 3 3 0 SmpA / OmlA family Nucleoporin_N PF08801.6 KND86563.1 - 0.34 9.6 0.7 2.1 6.9 0.0 2.3 2 1 0 3 3 3 0 Nup133 N terminal like Snf7 PF03357.16 KND86564.1 - 2.3e-39 134.5 8.7 2.6e-39 134.3 6.1 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KND86564.1 - 2.3e-05 24.5 3.6 0.0068 16.6 1.3 2.9 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 KND86564.1 - 0.00032 20.5 11.5 0.0028 17.5 7.5 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KND86564.1 - 0.0009 18.5 1.7 0.0032 16.7 0.3 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Exonuc_VII_L PF02601.10 KND86564.1 - 0.0081 15.3 1.8 0.0099 15.1 1.3 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF1395 PF07160.7 KND86564.1 - 0.01 15.3 3.3 0.59 9.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) DUF2205 PF10224.4 KND86564.1 - 0.021 14.3 7.9 0.026 14.0 2.5 2.9 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Zwint PF15556.1 KND86564.1 - 0.031 13.5 7.0 0.042 13.1 4.9 1.3 1 0 0 1 1 1 0 ZW10 interactor MitMem_reg PF13012.1 KND86564.1 - 0.032 14.3 5.0 0.19 11.8 3.4 2.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Prefoldin_2 PF01920.15 KND86564.1 - 0.041 13.6 12.1 0.4 10.4 0.0 4.0 2 1 0 2 2 2 0 Prefoldin subunit NuA4 PF09340.5 KND86564.1 - 0.047 13.3 2.7 0.1 12.2 1.9 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Sec34 PF04136.10 KND86564.1 - 0.073 12.7 4.6 1.5 8.4 1.6 2.1 1 1 0 2 2 2 0 Sec34-like family APG6 PF04111.7 KND86564.1 - 0.11 11.4 11.6 0.046 12.7 6.6 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF848 PF05852.6 KND86564.1 - 0.11 12.2 7.6 0.18 11.6 4.5 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) IFT46_B_C PF12317.3 KND86564.1 - 0.18 11.1 4.4 0.28 10.5 3.1 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal NYD-SP28_assoc PF14775.1 KND86564.1 - 0.22 11.2 6.3 2.7 7.7 1.3 3.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain Allexi_40kDa PF05549.6 KND86564.1 - 0.23 10.7 2.3 2.7 7.2 0.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4146 PF13652.1 KND86564.1 - 0.25 11.1 3.0 2.6 7.8 0.5 2.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4146) IncA PF04156.9 KND86564.1 - 0.29 10.7 7.2 4.3 6.8 5.0 2.3 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 KND86564.1 - 0.81 8.0 10.1 1.2 7.4 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 KND86564.1 - 0.88 7.9 8.4 1.5 7.1 5.7 1.4 1 1 0 1 1 1 0 AAA domain DUF972 PF06156.8 KND86564.1 - 0.97 9.8 9.6 3.7 7.9 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mod_r PF07200.8 KND86564.1 - 0.97 9.3 11.9 0.25 11.2 5.0 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.4 KND86564.1 - 1.2 7.9 7.9 1.9 7.3 5.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 KND86564.1 - 1.7 8.3 8.6 4.1 7.1 4.1 2.2 1 1 1 2 2 2 0 Laminin Domain II Mnd1 PF03962.10 KND86564.1 - 1.8 8.2 12.0 4.9 6.7 8.3 1.8 1 1 0 1 1 1 0 Mnd1 family COG2 PF06148.6 KND86564.1 - 2.3 8.0 8.1 2.6 7.8 2.9 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlxA PF14282.1 KND86564.1 - 2.6 8.0 11.6 4.7 7.2 6.9 2.0 1 1 1 2 2 2 0 FlxA-like protein OmpH PF03938.9 KND86564.1 - 2.8 7.8 15.6 0.79 9.6 5.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 KND86564.1 - 2.9 7.7 7.7 1.3 8.8 3.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FliD_N PF02465.13 KND86564.1 - 5.7 7.3 7.4 15 6.0 3.0 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4446 PF14584.1 KND86564.1 - 7.5 6.3 8.5 6.7 6.5 1.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF2408 PF10303.4 KND86564.1 - 7.6 6.6 9.5 33 4.5 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 KND86564.1 - 8.5 6.3 8.3 16 5.5 1.7 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Med4 PF10018.4 KND86564.1 - 8.6 5.7 10.7 6.1 6.1 0.1 2.8 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CLASP_N PF12348.3 KND86566.1 - 0.0014 18.0 0.0 0.0059 15.9 0.0 1.9 2 0 0 2 2 2 1 CLASP N terminal IncA PF04156.9 KND86566.1 - 0.0054 16.3 4.3 0.015 14.9 3.0 1.7 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 KND86566.1 - 0.018 14.1 6.7 0.034 13.1 4.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 MAP65_ASE1 PF03999.7 KND86566.1 - 0.022 13.4 4.9 0.039 12.5 3.4 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HEAT PF02985.17 KND86566.1 - 0.04 14.0 0.1 2.9 8.2 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat DUF972 PF06156.8 KND86566.1 - 1 9.7 4.6 15 6.0 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 KND86566.1 - 1.9 8.3 3.6 4.7 7.0 1.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 KND86566.1 - 3 7.5 10.6 0.022 14.4 1.1 2.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 KND86566.1 - 6.3 7.0 6.8 9.5 6.4 0.5 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.20 KND86567.1 - 1.3e-30 106.4 0.0 5.5e-30 104.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86567.1 - 9.1e-08 31.4 0.0 0.015 14.4 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KND86567.1 - 0.03 13.2 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like GCFC PF07842.7 KND86568.1 - 3.6e-67 226.6 1.4 3.6e-67 226.6 1.0 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KND86568.1 - 1.9e-13 49.9 2.5 1.9e-13 49.9 1.7 2.4 3 0 0 3 3 3 1 G-patch domain TIP_N PF12457.3 KND86568.1 - 4.6e-10 39.5 21.9 4.6e-10 39.5 15.2 3.2 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KND86568.1 - 3.9e-08 33.0 7.1 4.5e-08 32.8 0.7 3.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site ATP-synt_E PF05680.7 KND86568.1 - 0.72 9.8 5.1 2.2 8.3 3.5 1.8 1 0 0 1 1 1 0 ATP synthase E chain Cwf_Cwc_15 PF04889.7 KND86568.1 - 3.4 7.2 23.6 1.1 8.9 10.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 KND86568.1 - 6.5 5.1 16.4 20 3.5 11.5 1.4 1 1 0 1 1 1 0 Daxx Family SAPS PF04499.10 KND86569.1 - 2.2e-188 626.7 0.0 7.1e-188 625.0 0.0 1.9 1 1 0 1 1 1 1 SIT4 phosphatase-associated protein Condensation PF00668.15 KND86570.1 - 1.2e-68 231.1 0.1 2.9e-29 101.8 0.0 4.6 3 2 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 KND86570.1 - 1e-26 93.3 0.0 1.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KND86570.1 - 3.9e-07 30.2 0.1 1.7e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AXE1 PF05448.7 KND86570.1 - 1.1 7.6 0.0 1.9 6.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) OPT PF03169.10 KND86571.1 - 3.1e-168 561.0 47.5 3.6e-168 560.8 32.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-C2H2_4 PF13894.1 KND86572.1 - 0.0017 18.5 25.1 0.027 14.7 0.8 5.7 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KND86572.1 - 0.017 15.4 1.1 0.017 15.4 0.7 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND86572.1 - 0.043 14.1 0.2 0.043 14.1 0.1 4.1 5 1 0 5 5 5 0 Zinc-finger double domain zf-CHCC PF10276.4 KND86572.1 - 0.15 11.9 3.9 3.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 KND86572.1 - 5.6 7.2 9.2 0.34 11.1 1.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 KND86573.1 - 9.6e-16 57.5 0.0 8.2e-08 31.9 0.0 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Vfa1 PF08432.5 KND86574.1 - 7.2e-44 149.9 31.3 1.1e-43 149.4 21.7 1.3 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KND86574.1 - 0.00017 19.7 14.0 0.00017 19.7 9.7 1.1 1 0 0 1 1 1 1 CDC45-like protein U79_P34 PF03064.11 KND86574.1 - 0.00075 19.0 15.8 0.00097 18.7 10.9 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 GAGA_bind PF06217.7 KND86574.1 - 0.024 14.6 8.6 0.025 14.5 6.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 KND86574.1 - 0.14 9.8 13.9 0.16 9.7 9.6 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 KND86574.1 - 0.38 8.3 5.8 0.39 8.3 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 KND86574.1 - 0.41 9.9 28.4 0.56 9.5 19.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Borrelia_P83 PF05262.6 KND86574.1 - 0.46 8.7 19.4 0.52 8.5 13.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2201_N PF13203.1 KND86574.1 - 0.53 9.4 8.2 0.63 9.1 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SET PF00856.23 KND86574.1 - 0.72 10.1 3.7 0.92 9.7 2.6 1.1 1 0 0 1 1 1 0 SET domain NPR3 PF03666.8 KND86574.1 - 1.2 7.5 14.0 1.8 7.0 9.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.12 KND86574.1 - 1.4 8.6 8.6 2.3 7.9 6.0 1.4 1 0 0 1 1 1 0 DDHD domain Vma12 PF11712.3 KND86574.1 - 1.6 8.4 8.5 2 8.0 5.9 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TT_ORF2 PF02957.10 KND86574.1 - 1.7 9.3 14.4 2.9 8.6 10.0 1.4 1 0 0 1 1 1 0 TT viral ORF2 BTV_NS2 PF04514.7 KND86574.1 - 1.8 7.3 19.6 2.5 6.9 13.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Atg14 PF10186.4 KND86574.1 - 2.1 7.1 9.6 2.9 6.7 6.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2722 PF10846.3 KND86574.1 - 2.5 7.0 16.3 3.9 6.3 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2413 PF10310.4 KND86574.1 - 2.6 6.7 20.0 3.3 6.4 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SAPS PF04499.10 KND86574.1 - 3.9 5.9 16.8 4.7 5.7 11.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FLO_LFY PF01698.11 KND86574.1 - 4.5 6.0 16.3 6.2 5.5 11.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 KND86574.1 - 5 6.0 5.5 5.8 5.8 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rtt106 PF08512.7 KND86575.1 - 1.9e-22 79.0 0.0 3.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CENP-T PF15511.1 KND86575.1 - 0.16 11.1 23.8 0.27 10.4 16.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 KND86575.1 - 2.5 5.9 34.1 3.5 5.4 23.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KND86575.1 - 3.8 6.6 26.6 6 6.0 18.4 1.3 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 KND86575.1 - 4 6.9 19.5 8.2 5.9 13.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 KND86575.1 - 4 5.8 26.6 6.1 5.2 18.4 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 KND86575.1 - 4 6.7 17.3 6.7 6.0 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleos_tra2_C PF07662.8 KND86578.1 - 2.1e-67 226.6 1.2 2.1e-67 226.6 0.8 2.8 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KND86578.1 - 1.1e-21 76.9 1.3 1.1e-21 76.9 0.9 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KND86578.1 - 0.00086 19.1 7.4 0.00086 19.1 5.1 3.3 3 1 1 4 4 4 1 Nucleoside recognition Acetyltransf_2 PF00797.12 KND86580.1 - 1.9e-44 152.0 0.0 2.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 KND86580.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily Aminotran_3 PF00202.16 KND86581.1 - 4.7e-83 278.8 0.1 5.7e-83 278.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Kinesin PF00225.18 KND86582.1 - 1e-57 195.3 0.0 1.6e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Ish1 PF10281.4 KND86582.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Glyco_hydro_47 PF01532.15 KND86583.1 - 7.9e-157 522.5 0.0 9.1e-157 522.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Amidohydro_3 PF07969.6 KND86584.1 - 5.9e-58 197.0 0.4 6.9e-58 196.7 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND86584.1 - 3.1e-08 33.3 0.0 8.4e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KND86584.1 - 1.1e-07 31.8 0.0 0.00027 20.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KND86584.1 - 0.007 16.4 5.2 0.055 13.4 0.1 3.0 3 0 0 3 3 3 1 Amidohydrolase Saccharop_dh PF03435.13 KND86585.1 - 4e-109 365.1 0.0 9.1e-106 354.0 0.0 2.0 1 1 1 2 2 2 2 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KND86585.1 - 2.8e-07 30.7 1.6 5.1e-07 29.8 1.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KND86585.1 - 3.2e-07 30.5 0.1 6.4e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KND86585.1 - 0.00074 19.8 0.3 0.0015 18.9 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KND86585.1 - 0.0074 15.5 1.0 0.011 14.9 0.7 1.3 1 0 0 1 1 1 1 NmrA-like family YfmQ PF10787.4 KND86585.1 - 0.03 13.6 0.1 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group GFO_IDH_MocA PF01408.17 KND86585.1 - 0.057 13.9 0.5 0.11 13.0 0.3 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 KND86585.1 - 0.075 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_3 PF03447.11 KND86585.1 - 0.11 12.8 0.7 0.21 11.9 0.5 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF3429 PF11911.3 KND86586.1 - 3.6e-40 137.2 8.5 4.7e-40 136.8 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) HNH_3 PF13392.1 KND86586.1 - 0.019 14.3 0.6 0.037 13.4 0.4 1.5 1 0 0 1 1 1 0 HNH endonuclease Herpes_gE PF02480.11 KND86586.1 - 0.13 10.5 0.0 0.21 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Neur_chan_memb PF02932.11 KND86586.1 - 2.4 8.0 4.4 4.3 7.1 3.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1162 PF06650.7 KND86587.1 - 1.7e-87 293.1 0.2 1e-85 287.3 0.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KND86587.1 - 1e-41 141.1 0.0 3.1e-41 139.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KND86587.1 - 0.0001 22.3 0.1 0.00037 20.5 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain p450 PF00067.17 KND86588.1 - 2.6e-70 237.2 0.0 3e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 KND86589.1 - 1.6e-48 165.0 0.0 2.1e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KND86589.1 - 1.7e-25 89.0 0.0 5.3e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.1 KND86590.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND86590.1 - 1.3e-08 34.6 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KND86590.1 - 8.5e-08 32.2 0.0 2.2e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KND86590.1 - 6.4e-06 26.0 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND86590.1 - 0.00024 20.9 0.2 0.00081 19.2 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND86590.1 - 0.059 13.8 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 KND86591.1 - 8.8e-25 87.0 0.2 3e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86591.1 - 1.1e-07 31.5 7.5 1.1e-07 31.5 5.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FBA PF04300.8 KND86591.1 - 0.053 13.4 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 F-box associated region FAD_binding_3 PF01494.14 KND86592.1 - 2.2e-22 79.5 0.0 3.3e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KND86592.1 - 1e-08 34.5 0.2 5.2e-06 25.5 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND86592.1 - 1.9e-07 31.0 0.3 4.6e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND86592.1 - 4.4e-07 29.0 0.4 6.9e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KND86592.1 - 2.6e-06 27.4 0.1 5.8e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND86592.1 - 5.9e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND86592.1 - 0.00012 22.4 0.4 0.00034 20.9 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KND86592.1 - 0.00018 20.4 0.3 0.00029 19.8 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KND86592.1 - 0.00019 20.0 0.4 0.00029 19.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KND86592.1 - 0.0016 17.6 0.7 0.0024 17.0 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KND86592.1 - 0.0032 17.0 0.1 0.0063 16.0 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KND86592.1 - 0.0046 16.0 0.1 0.0072 15.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KND86592.1 - 0.0067 15.1 0.0 0.2 10.2 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.13 KND86592.1 - 0.0091 15.6 0.6 0.016 14.8 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 KND86592.1 - 0.011 14.7 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UPF0104 PF03706.8 KND86592.1 - 0.034 13.4 0.1 0.076 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Glyco_transf_4 PF13439.1 KND86592.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ApbA PF02558.11 KND86592.1 - 0.043 13.2 0.1 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KND86592.1 - 0.044 12.7 0.3 0.32 9.8 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KND86592.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 KND86592.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 KND86592.1 - 0.089 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.1 KND86592.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 KND86592.1 - 0.12 11.1 0.0 0.36 9.6 0.0 1.6 1 1 1 2 2 2 0 Squalene epoxidase Peptidase_A4 PF01828.12 KND86593.1 - 1.4e-74 249.7 6.8 1.6e-74 249.4 4.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family Glyoxalase PF00903.20 KND86594.1 - 7.6e-07 29.1 0.3 1.9e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KND86594.1 - 4.3e-06 27.3 0.2 9.5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain DUF4396 PF14342.1 KND86595.1 - 1.7e-44 151.3 6.3 1.7e-44 151.3 4.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) BCS1_N PF08740.6 KND86596.1 - 2.6e-11 43.4 0.1 3.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal Actin PF00022.14 KND86597.1 - 5.1e-116 387.3 0.0 6.3e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KND86597.1 - 0.0069 15.0 0.0 0.051 12.1 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Ank_2 PF12796.2 KND86598.1 - 1.9e-111 364.6 15.9 1.9e-21 76.1 0.3 7.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KND86598.1 - 8.5e-96 309.3 30.5 9.2e-09 34.6 0.0 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.1 KND86598.1 - 1.4e-83 266.3 5.8 2e-06 27.4 0.0 14.6 14 1 1 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 KND86598.1 - 3e-74 244.2 13.1 6e-11 42.5 0.0 10.8 4 4 9 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND86598.1 - 2.5e-58 192.7 36.0 1.3e-09 37.9 0.1 13.4 3 2 11 14 14 14 13 Ankyrin repeats (many copies) CholecysA-Rec_N PF09193.5 KND86598.1 - 0.00078 19.2 0.0 10 6.1 0.0 4.8 6 0 0 6 6 6 1 Cholecystokinin A receptor, N-terminal DUF482 PF04339.7 KND86598.1 - 0.2 10.4 0.0 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF482 Hydrolase_like PF13242.1 KND86598.1 - 0.78 9.4 10.0 2.8 7.7 0.1 4.1 5 0 0 5 5 5 0 HAD-hyrolase-like Pkinase PF00069.20 KND86599.1 - 1.9e-16 59.9 0.0 4.4e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain FHA PF00498.21 KND86599.1 - 1.5e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.12 KND86599.1 - 5.1e-07 29.0 0.0 1.7e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2156 PF09924.4 KND86600.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) Pkinase PF00069.20 KND86602.1 - 1.5e-08 34.1 0.2 5.3e-08 32.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain DUF1700 PF08006.6 KND86603.1 - 0.083 12.1 0.0 0.09 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3859 PF12975.2 KND86605.1 - 0.087 12.4 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) NDUF_B4 PF07225.7 KND86605.1 - 0.26 11.1 5.0 1.2 8.9 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2306 PF10067.4 KND86607.1 - 7e-10 38.9 9.2 7e-10 38.9 6.4 2.3 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF997 PF06196.7 KND86607.1 - 1 8.9 11.3 0.032 13.7 2.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF997) NfeD PF01957.13 KND86607.1 - 2.4 8.3 9.3 11 6.1 0.1 2.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PrgI PF12666.2 KND86607.1 - 6.7 6.9 8.7 0.86 9.7 2.0 2.4 2 0 0 2 2 2 0 PrgI family protein DUF4383 PF14325.1 KND86608.1 - 1 9.4 9.7 0.035 14.1 2.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) TRI12 PF06609.8 KND86609.1 - 1.8e-23 82.6 22.3 2.8e-23 81.9 15.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KND86609.1 - 4.1e-22 78.3 48.5 3.7e-21 75.2 30.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86609.1 - 9.3e-09 34.3 28.9 2.1e-07 29.8 5.2 3.0 1 1 0 2 2 2 2 Sugar (and other) transporter PIRT PF15099.1 KND86609.1 - 0.07 12.3 0.1 0.27 10.4 0.1 2.0 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family HisKA_3 PF07730.8 KND86610.1 - 0.0049 17.1 3.6 0.86 9.9 0.2 2.9 2 1 1 3 3 3 2 Histidine kinase Mnd1 PF03962.10 KND86610.1 - 0.012 15.2 6.1 0.02 14.5 4.2 1.3 1 0 0 1 1 1 0 Mnd1 family COG2 PF06148.6 KND86610.1 - 0.027 14.3 2.6 0.67 9.8 0.2 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 KND86610.1 - 0.034 13.1 4.2 0.045 12.8 2.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 KND86610.1 - 0.038 11.3 8.4 0.066 10.5 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF342 PF03961.8 KND86610.1 - 0.043 12.2 1.4 0.049 12.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 KND86610.1 - 0.15 11.5 5.3 0.5 9.8 0.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF948 PF06103.6 KND86610.1 - 0.21 11.4 1.2 15 5.5 0.0 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 KND86610.1 - 0.48 10.4 5.6 0.36 10.8 2.6 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.10 KND86610.1 - 0.7 9.0 5.8 1.2 8.3 4.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.8 KND86610.1 - 2.5 8.5 6.3 20 5.6 0.3 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 KND86610.1 - 2.8 7.4 11.2 6 6.4 7.6 1.5 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 KND86610.1 - 3 8.2 7.3 5.8 7.3 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Syntaxin-6_N PF09177.6 KND86610.1 - 3.3 8.1 6.5 10 6.6 0.9 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.9 KND86610.1 - 3.4 7.5 7.3 1.8 8.4 3.5 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Flavoprotein PF02441.14 KND86611.1 - 4.1e-40 136.4 0.6 5.5e-40 136.0 0.4 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 KND86612.1 - 6.5e-15 54.8 0.0 9.5e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin PDZ_assoc PF10600.4 KND86612.1 - 0.0064 16.7 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors Aminotran_4 PF01063.14 KND86613.1 - 7.3e-26 91.0 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Methyltransf_11 PF08241.7 KND86614.1 - 6.1e-13 49.0 0.0 9.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86614.1 - 1.4e-10 41.7 0.1 2.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND86614.1 - 5e-08 32.8 0.0 5.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND86614.1 - 5.4e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86614.1 - 6.5e-07 29.3 0.1 1.1e-06 28.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND86614.1 - 9.3e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86614.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND86614.1 - 3.7e-05 22.9 0.1 4.9e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KND86614.1 - 0.00044 19.6 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KND86614.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KND86614.1 - 0.042 12.9 0.0 0.072 12.1 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.21 KND86614.1 - 0.092 12.2 0.4 0.31 10.6 0.2 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 KND86614.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase N2227 PF07942.7 KND86614.1 - 0.14 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Sugar_tr PF00083.19 KND86615.1 - 3e-79 266.7 24.9 8.5e-79 265.2 17.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND86615.1 - 2.5e-28 98.8 28.5 2.5e-28 98.8 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.16 KND86617.1 - 5.9e-35 120.7 0.0 9e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KND86617.1 - 1.6e-14 53.2 0.0 2.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND86617.1 - 1.8e-09 37.4 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND86617.1 - 5.2e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KND86618.1 - 1.2e-07 31.5 8.1 2.1e-07 30.7 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSF PF00474.12 KND86619.1 - 3.8e-23 81.8 24.7 3.9e-23 81.7 16.1 1.8 1 1 1 2 2 2 1 Sodium:solute symporter family MFS_1 PF07690.11 KND86620.1 - 9.7e-19 67.2 61.1 8.4e-18 64.1 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CTP_transf_2 PF01467.21 KND86621.1 - 4.8e-17 62.4 0.1 8.2e-14 51.9 0.0 3.3 2 1 0 2 2 2 2 Cytidylyltransferase DeoRC PF00455.17 KND86621.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain Pkinase_Tyr PF07714.12 KND86622.1 - 1.5e-15 56.9 0.0 3.1e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND86622.1 - 2.6e-15 56.2 0.0 3.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND86622.1 - 0.035 13.1 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND86622.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_S24e PF01282.14 KND86623.1 - 3.7e-33 113.1 0.0 5.7e-33 112.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e GST_N_3 PF13417.1 KND86624.1 - 7.7e-14 51.6 0.0 1.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND86624.1 - 5.7e-13 48.6 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KND86624.1 - 1.2e-07 31.8 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KND86624.1 - 1.5e-06 27.9 0.4 1.5e-06 27.9 0.3 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Arf PF00025.16 KND86625.1 - 6.3e-75 250.2 0.2 7.1e-75 250.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KND86625.1 - 2.4e-13 49.7 0.0 2.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KND86625.1 - 5.7e-13 48.3 1.9 1.2e-09 37.3 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KND86625.1 - 4.1e-12 45.6 0.0 5.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KND86625.1 - 7.1e-12 44.9 0.0 8.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KND86625.1 - 9.4e-08 32.5 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KND86625.1 - 0.00037 20.4 0.0 0.0005 19.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KND86625.1 - 0.027 13.5 0.3 0.058 12.4 0.2 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Pkinase PF00069.20 KND86626.1 - 2.4e-56 190.7 0.0 1.4e-54 184.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86626.1 - 2e-28 99.1 0.0 8e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KND86626.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HemX PF04375.9 KND86626.1 - 0.11 11.0 0.9 0.19 10.2 0.6 1.3 1 0 0 1 1 1 0 HemX SelP_N PF04592.9 KND86626.1 - 6.6 6.0 9.2 13 5.1 6.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PMI_typeI PF01238.16 KND86627.1 - 4.7e-132 440.4 0.0 5.6e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I CRISPR_Cse2 PF09485.5 KND86627.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) AraC_binding PF02311.14 KND86627.1 - 0.089 12.4 0.0 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF1325 PF07039.6 KND86628.1 - 1.5e-25 89.2 0.0 2.2e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Pro_CA PF00484.14 KND86629.1 - 4e-25 88.5 0.1 7e-25 87.8 0.1 1.4 1 1 0 1 1 1 1 Carbonic anhydrase Acetyltransf_1 PF00583.19 KND86630.1 - 0.0025 17.7 0.1 0.047 13.7 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) family Amidase PF01425.16 KND86631.1 - 1.2e-96 324.3 0.2 1.5e-96 323.9 0.1 1.1 1 0 0 1 1 1 1 Amidase RF-1 PF00472.15 KND86632.1 - 1.7e-33 114.8 2.3 2.9e-33 114.0 1.6 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KND86632.1 - 2.4e-21 75.5 0.0 5.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 PCRF domain Amidase PF01425.16 KND86633.1 - 1.2e-100 337.4 0.0 1.4e-100 337.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 KND86634.1 - 1.4e-11 43.7 0.6 2.8e-11 42.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KND86634.1 - 2.7e-09 36.8 11.5 1.9e-05 24.7 3.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND86634.1 - 1.1e-07 31.6 11.0 9.7e-05 22.4 2.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND86634.1 - 1.2e-05 25.3 13.2 4e-05 23.6 2.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 KND86634.1 - 0.0088 15.6 2.0 0.025 14.2 1.4 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KND86634.1 - 0.05 13.7 0.5 0.05 13.7 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.15 KND86634.1 - 0.2 11.3 3.8 0.38 10.5 2.6 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Asp_Glu_race PF01177.17 KND86635.1 - 2.2e-21 76.7 0.1 2.7e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Methyltransf_16 PF10294.4 KND86636.1 - 6e-18 64.8 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KND86636.1 - 1.3e-05 25.7 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND86636.1 - 0.00044 19.6 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KND86636.1 - 0.005 16.4 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 KND86636.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KND86636.1 - 0.055 13.0 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KND86636.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KND86636.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FliT PF05400.8 KND86637.1 - 0.02 15.3 6.2 0.17 12.3 1.1 2.6 2 1 0 2 2 2 0 Flagellar protein FliT RAP1 PF07218.6 KND86637.1 - 0.14 10.1 0.4 0.16 10.0 0.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4657 PF15552.1 KND86638.1 - 0.068 12.4 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) DAO PF01266.19 KND86640.1 - 2.7e-23 82.4 2.4 3.5e-23 82.0 1.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND86640.1 - 0.00051 20.4 3.1 0.001 19.4 2.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND86640.1 - 0.0086 16.1 0.2 0.037 14.0 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND86640.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND86640.1 - 0.13 12.3 1.2 0.39 10.7 0.8 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KND86640.1 - 0.15 11.1 1.3 0.25 10.3 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KND86640.1 - 0.2 11.3 0.6 0.35 10.4 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KND86640.1 - 0.41 9.9 1.3 0.66 9.3 0.9 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 KND86640.1 - 0.42 9.6 2.1 0.49 9.4 0.2 1.8 2 0 0 2 2 2 0 Thi4 family G_glu_transpept PF01019.16 KND86641.1 - 8.7e-132 440.1 0.0 1.5e-131 439.4 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase NMT1_2 PF13379.1 KND86641.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Sugar_tr PF00083.19 KND86642.1 - 2.4e-71 240.6 22.0 3.3e-71 240.1 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND86642.1 - 2.4e-17 62.7 36.0 7.8e-14 51.1 17.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND86642.1 - 0.00016 20.2 23.7 0.00061 18.3 5.7 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein His_Phos_1 PF00300.17 KND86644.1 - 1.8e-16 60.6 0.0 3.2e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M20 PF01546.23 KND86646.1 - 5.9e-22 78.0 0.0 8.7e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND86646.1 - 0.00036 20.2 0.1 0.00071 19.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KND86646.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 GCS PF03074.11 KND86648.1 - 2.8e-153 510.3 0.0 5.4e-153 509.4 0.0 1.4 1 1 0 1 1 1 1 Glutamate-cysteine ligase UPF0160 PF03690.8 KND86650.1 - 1.2e-117 392.8 0.0 1.4e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF3669 PF12417.3 KND86651.1 - 1.1e-18 66.7 0.0 2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Tubulin PF00091.20 KND86652.1 - 2e-62 210.8 0.0 3.1e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KND86652.1 - 1.7e-45 154.1 0.1 3.4e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain MFS_1 PF07690.11 KND86652.1 - 1.3e-33 116.1 50.8 5e-29 101.1 22.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND86652.1 - 8.9e-08 30.9 24.9 5.6e-06 25.0 7.5 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KND86652.1 - 7.8e-05 22.3 7.4 0.0024 17.6 3.8 3.5 3 0 0 3 3 3 1 MFS_1 like family Fungal_trans PF04082.13 KND86653.1 - 1.1e-17 63.8 4.7 1.8e-17 63.0 3.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86653.1 - 7.5e-05 22.5 8.4 0.00012 21.9 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_gE PF02480.11 KND86653.1 - 0.046 11.9 0.1 0.43 8.7 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 KND86654.1 - 4.1e-37 127.7 34.5 5.5e-37 127.2 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Spermine_synth PF01564.12 KND86655.1 - 6.4e-95 316.7 0.1 1.2e-94 315.9 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KND86655.1 - 0.0057 17.2 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KND86655.1 - 0.026 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_31 PF13847.1 KND86655.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.17 KND86656.1 - 2.1e-28 98.9 0.0 3.4e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Claudin_2 PF13903.1 KND86657.1 - 1.4e-09 37.8 6.3 1.9e-09 37.4 4.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KND86657.1 - 0.00011 21.9 5.9 0.00021 21.0 4.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family stn_TNFRSF12A PF12191.3 KND86657.1 - 0.055 13.5 1.9 0.31 11.0 0.3 2.1 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Claudin_3 PF06653.6 KND86657.1 - 0.2 11.3 8.8 3.6 7.2 6.1 2.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DuoxA PF10204.4 KND86657.1 - 0.34 9.9 3.3 0.13 11.3 0.4 1.7 2 0 0 2 2 2 0 Dual oxidase maturation factor MARVEL PF01284.18 KND86657.1 - 2.4 8.0 14.1 20 4.9 9.9 2.3 1 1 0 1 1 1 0 Membrane-associating domain DUF308 PF03729.8 KND86657.1 - 9 6.3 14.4 0.22 11.5 1.6 3.0 2 1 0 3 3 3 0 Short repeat of unknown function (DUF308) PhyH PF05721.8 KND86658.1 - 7.5e-60 202.5 0.0 9e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KND86658.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2373 PF10180.4 KND86659.1 - 4.1e-21 74.3 0.6 8.2e-21 73.3 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 KND86660.1 - 3e-49 166.8 0.1 4.1e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KND86660.1 - 7e-10 38.0 0.1 7e-10 38.0 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 KND86660.1 - 0.02 15.1 0.0 0.049 13.9 0.0 1.6 2 0 0 2 2 2 0 SCP-2 sterol transfer family IF-2B PF01008.12 KND86660.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF3650 PF12368.3 KND86660.1 - 0.26 10.8 3.0 0.17 11.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) WD40 PF00400.27 KND86661.1 - 4.4e-47 156.3 17.3 1.3e-11 43.8 0.0 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KND86661.1 - 3.2e-08 32.1 1.0 0.24 9.4 0.1 4.9 4 1 1 5 5 5 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KND86661.1 - 0.0012 17.6 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region DUF3312 PF11768.3 KND86661.1 - 0.0027 16.0 0.0 0.0046 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Nbas_N PF15492.1 KND86661.1 - 0.036 13.1 0.0 1.9 7.4 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF2244 PF10003.4 KND86661.1 - 0.084 12.2 0.0 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) UPF0546 PF10639.4 KND86662.1 - 6.4e-35 119.3 0.1 1.9e-34 117.8 0.1 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 KND86662.1 - 0.034 14.1 6.5 0.034 14.2 3.2 1.8 2 0 0 2 2 2 0 EamA-like transporter family DUF2809 PF10990.3 KND86662.1 - 0.091 13.1 0.1 0.4 11.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2809) DUF3115 PF11312.3 KND86663.1 - 1.5e-84 283.6 0.0 2.3e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 KND86664.1 - 3.8e-155 515.7 0.0 5.1e-155 515.3 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KND86664.1 - 2.5e-45 154.1 0.0 4e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KND86664.1 - 3.6e-14 52.7 0.0 7.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KND86664.1 - 0.00028 19.9 0.0 0.00073 18.5 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KND86664.1 - 0.026 13.2 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component ATP-synt_C PF00137.16 KND86665.1 - 7.6e-27 93.0 27.5 3.1e-12 46.2 5.5 3.1 3 0 0 3 3 3 3 ATP synthase subunit C DUF2592 PF10766.4 KND86665.1 - 0.44 9.9 6.1 1.7 8.0 4.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Flavi_NS4A PF01350.12 KND86665.1 - 0.66 9.5 3.5 0.36 10.3 1.0 1.5 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Bax1-I PF01027.15 KND86665.1 - 1.3 8.5 8.2 1.9 8.0 5.7 1.3 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2970 PF11174.3 KND86665.1 - 4.1 7.0 7.0 1.7 8.3 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Syja_N PF02383.13 KND86666.1 - 2.3e-96 322.3 0.0 3.1e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KND86666.1 - 1.2e-33 114.9 0.0 2e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase PLDc PF00614.17 KND86667.1 - 2.6e-17 61.9 1.1 2e-08 33.7 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KND86667.1 - 1e-11 44.6 0.1 3.1e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KND86667.1 - 5.6e-06 26.1 0.5 3.8e-05 23.4 0.1 2.6 2 1 0 2 2 2 1 PX domain ERG4_ERG24 PF01222.12 KND86668.1 - 4.9e-138 460.2 23.6 5.7e-138 460.0 16.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Plus-3 PF03126.13 KND86669.1 - 1.6e-25 89.2 0.0 3.7e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.8 KND86670.1 - 2.3e-63 212.7 0.1 3e-63 212.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KND86670.1 - 0.003 17.8 0.0 0.0056 17.0 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin Fungal_trans PF04082.13 KND86671.1 - 9.3e-33 113.1 0.3 1.6e-32 112.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86671.1 - 1.3e-10 40.9 11.2 3.7e-10 39.5 7.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC144C PF14915.1 KND86671.1 - 0.056 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region GDPD PF03009.12 KND86672.1 - 2.9e-25 89.2 0.0 1.7e-19 70.3 0.0 2.4 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KND86672.1 - 0.095 12.9 6.3 2.9 8.2 0.5 3.5 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family G-alpha PF00503.15 KND86673.1 - 3.4e-119 398.0 0.4 4.2e-119 397.7 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KND86673.1 - 1.4e-13 50.5 1.6 2.4e-08 33.4 0.0 2.6 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND86673.1 - 0.00048 19.3 0.2 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KND86673.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KND86673.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 KND86674.1 - 4.5e-06 26.2 0.5 4.5e-06 26.2 0.4 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KND86674.1 - 3.1e-05 23.4 0.8 3.1e-05 23.4 0.5 2.7 3 0 0 3 3 3 1 F-box domain TPR_11 PF13414.1 KND86674.1 - 9.3e-05 21.9 0.9 0.14 11.8 0.0 3.0 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KND86674.1 - 0.00072 19.2 1.2 0.015 15.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PRANC PF09372.5 KND86674.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 PRANC domain TPR_1 PF00515.23 KND86674.1 - 0.084 12.5 0.7 3 7.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KND86674.1 - 0.19 12.4 0.5 2.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 KND86674.1 - 0.33 10.6 0.1 0.33 10.6 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) SET PF00856.23 KND86675.1 - 0.015 15.6 0.0 0.076 13.3 0.0 2.1 1 1 0 1 1 1 0 SET domain MMR_HSR1_C PF08438.5 KND86676.1 - 8.3e-33 112.8 0.0 1.7e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KND86676.1 - 1.6e-18 66.7 0.0 3.6e-18 65.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND86676.1 - 6.2e-09 35.3 0.1 1.8e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KND86676.1 - 0.0013 18.1 0.5 1.2 8.5 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KND86676.1 - 0.0021 17.9 0.9 0.16 11.8 0.2 3.1 3 0 0 3 3 3 1 Dynamin family ArgK PF03308.11 KND86676.1 - 0.032 13.0 0.1 0.15 10.7 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 KND86676.1 - 0.1 12.9 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF2011 PF09428.5 KND86677.1 - 0.01 15.7 0.1 0.028 14.2 0.1 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) FHA PF00498.21 KND86678.1 - 3.7e-13 49.3 0.0 7.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.11 KND86679.1 - 9e-30 103.5 31.7 9e-30 103.5 22.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86679.1 - 1.3e-12 47.1 11.5 1.3e-12 47.1 8.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Trypan_PARP PF05887.6 KND86679.1 - 0.0012 18.7 13.9 0.0012 18.7 9.7 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.8 KND86679.1 - 0.0028 17.7 5.1 0.0068 16.4 3.5 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Neisseria_TspB PF05616.8 KND86679.1 - 8.7 4.5 19.2 14 3.9 13.3 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Thymidylat_synt PF00303.14 KND86680.1 - 1.1e-113 378.7 0.0 1.3e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase IFRD PF05004.8 KND86681.1 - 3.1e-27 95.4 0.1 4.2e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 KND86681.1 - 0.037 14.3 0.5 0.31 11.3 0.2 2.8 2 1 0 2 2 2 0 HEAT repeats Btz PF09405.5 KND86683.1 - 8.7e-27 93.7 2.3 2e-26 92.5 1.6 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Ran_BP1 PF00638.13 KND86685.1 - 5.7e-11 42.5 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 KND86685.1 - 0.0039 17.3 26.8 0.0039 17.3 18.6 9.6 3 2 6 9 9 9 4 Nucleoporin FG repeat region ZZ PF00569.12 KND86686.1 - 9.3e-18 63.5 60.8 5.8e-06 25.7 5.4 4.7 4 1 0 4 4 4 4 Zinc finger, ZZ type BMP2K_C PF15282.1 KND86686.1 - 0.0024 18.1 0.6 0.0024 18.1 0.4 1.8 2 0 0 2 2 2 1 BMP-2-inducible protein kinase C-terminus CBS PF00571.23 KND86687.1 - 1.8e-33 114.0 7.0 2.4e-13 49.6 0.1 4.2 4 0 0 4 4 4 4 CBS domain NDUFA12 PF05071.11 KND86688.1 - 3.4e-24 85.3 0.1 4.1e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 KND86689.1 - 6.7e-10 38.7 0.0 0.00042 20.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KND86689.1 - 4.9e-05 22.9 3.6 0.7 9.7 0.1 3.5 3 0 0 3 3 3 3 Phospholipase D Active site motif An_peroxidase PF03098.10 KND86690.1 - 2.5e-87 293.4 0.0 5e-85 285.8 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KND86690.1 - 2.3e-07 29.7 0.0 4.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 KND86691.1 - 2.9e-10 39.1 0.1 0.00049 18.6 0.1 3.2 3 0 0 3 3 3 3 Transferase family Glyco_hydro_18 PF00704.23 KND86692.1 - 8.2e-11 41.9 5.4 2.9e-10 40.1 3.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 KND86692.1 - 1.1e-09 37.7 16.1 4.8e-09 35.7 11.1 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2235 PF09994.4 KND86693.1 - 1.8e-72 244.0 1.6 2.2e-71 240.4 1.1 2.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Alb1 PF09135.6 KND86694.1 - 3.9e-23 82.1 9.7 5.8e-23 81.6 6.7 1.3 1 0 0 1 1 1 1 Alb1 DUF566 PF04484.7 KND86694.1 - 0.14 11.6 7.6 0.2 11.1 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Nop25 PF09805.4 KND86694.1 - 0.68 9.9 8.1 1.4 8.9 5.6 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Amidase PF01425.16 KND86695.1 - 1.1e-19 70.6 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Amidase 2-Hacid_dh_C PF02826.14 KND86696.1 - 2.3e-36 124.6 0.0 2.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KND86696.1 - 2e-06 27.7 0.0 5.1e-06 26.4 0.0 1.6 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 KND86696.1 - 0.023 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KND86696.1 - 0.029 14.8 0.1 0.082 13.3 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KND86696.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold KAT11 PF08214.6 KND86697.1 - 7.3e-90 301.5 0.0 9.2e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein MFS_1 PF07690.11 KND86698.1 - 4e-28 98.1 26.5 4e-28 98.1 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KND86699.1 - 2.1e-07 30.7 8.6 4e-07 29.8 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KND86700.1 - 6.5e-82 275.7 0.0 2.3e-81 273.8 0.0 1.7 2 0 0 2 2 2 1 Amidase Ras PF00071.17 KND86702.1 - 1.1e-31 109.4 0.2 1.3e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND86702.1 - 6.4e-21 75.0 0.1 2.3e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KND86702.1 - 1.6e-06 27.4 0.1 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND86702.1 - 0.00011 21.4 0.2 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND86702.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KND86702.1 - 0.076 11.6 0.1 0.17 10.5 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit PLAC8 PF04749.12 KND86704.1 - 1.5e-06 28.7 2.8 2.6e-06 27.9 1.9 1.3 1 0 0 1 1 1 1 PLAC8 family PNTB PF02233.11 KND86706.1 - 1.5e-164 548.2 22.3 1.5e-164 548.2 15.5 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KND86706.1 - 4e-53 179.4 0.8 7.8e-53 178.4 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KND86706.1 - 1.1e-49 167.9 0.4 6.3e-49 165.4 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KND86706.1 - 6.9e-31 106.2 3.6 6.9e-31 106.2 2.5 5.7 5 2 2 7 7 7 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KND86706.1 - 0.0003 19.9 1.6 0.25 10.4 0.0 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KND86706.1 - 0.0019 17.7 0.3 0.0065 16.0 0.2 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KND86706.1 - 0.018 14.9 0.2 0.05 13.4 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 KND86706.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Methyltransf_31 PF13847.1 KND86706.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KND86706.1 - 0.085 13.4 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 KND86706.1 - 6.9 6.7 9.5 0.36 10.8 1.2 3.0 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GCV_H PF01597.14 KND86707.1 - 4.4e-31 107.0 0.4 5.5e-31 106.7 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein GvpO PF05800.6 KND86707.1 - 0.081 12.8 0.2 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpO Porphobil_deam PF01379.15 KND86708.1 - 1.6e-78 262.5 0.0 2.4e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KND86708.1 - 1.9e-18 66.2 1.0 4e-18 65.3 0.3 1.8 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain VCBS PF13517.1 KND86709.1 - 1.1e-08 35.3 10.2 2.4e-05 24.5 1.0 3.4 1 1 4 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KND86709.1 - 4.7e-05 22.9 1.4 0.014 15.0 0.0 3.5 4 0 0 4 4 4 2 FG-GAP repeat Polyoma_lg_T_C PF06431.6 KND86709.1 - 0.0043 15.7 0.1 0.0064 15.2 0.1 1.2 1 0 0 1 1 1 1 Polyomavirus large T antigen C-terminus DUF1649 PF07855.7 KND86709.1 - 0.072 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) PBP PF01161.15 KND86710.1 - 9e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.17 KND86711.1 - 1e-43 148.9 0.0 1.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family bZIP_1 PF00170.16 KND86712.1 - 1.1e-08 34.9 4.0 2e-08 34.0 2.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND86712.1 - 1.2e-07 31.4 0.9 1.9e-07 30.7 0.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KND86712.1 - 2.7e-07 30.8 2.3 4.2e-07 30.1 1.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1043 PF06295.7 KND86712.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RhoGAP PF00620.22 KND86713.1 - 5.1e-07 29.4 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Bap31 PF05529.7 KND86713.1 - 0.14 11.5 2.1 0.26 10.7 1.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like MAD PF05557.8 KND86713.1 - 0.22 9.5 3.7 0.32 9.0 2.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Rep_fac-A_3 PF08661.6 KND86714.1 - 7.3e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Replication factor A protein 3 Arm PF00514.18 KND86716.1 - 4.1e-71 232.6 32.2 1.5e-13 49.9 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KND86716.1 - 2.5e-23 82.1 14.7 2.8e-07 30.7 0.2 7.6 3 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 KND86716.1 - 2e-19 67.8 15.5 0.017 15.1 0.0 9.5 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KND86716.1 - 5.5e-17 61.6 13.3 0.00044 20.6 0.2 8.7 6 2 3 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 KND86716.1 - 7.1e-13 47.7 7.6 1.1e-07 30.5 0.2 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KND86716.1 - 3.3e-11 42.7 8.3 0.00079 18.6 0.7 3.4 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 KND86716.1 - 1.6e-09 36.2 0.8 3e-09 35.4 0.5 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KND86716.1 - 4.1e-09 36.0 1.3 0.00021 20.5 0.5 3.1 1 1 1 2 2 2 2 V-ATPase subunit H DUF908 PF06012.7 KND86716.1 - 0.0005 19.4 2.6 0.65 9.2 0.1 3.8 2 1 2 4 4 4 2 Domain of Unknown Function (DUF908) DUF2454 PF10521.4 KND86716.1 - 0.00069 18.7 0.8 0.0062 15.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) HEAT_PBS PF03130.11 KND86716.1 - 0.016 15.6 7.5 31 5.4 0.2 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 KND86716.1 - 0.039 14.3 0.2 3.2 8.2 0.0 3.5 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region UQ_con PF00179.21 KND86717.1 - 9.9e-50 167.6 0.1 1.1e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND86717.1 - 0.00014 21.6 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND86717.1 - 0.035 13.9 1.0 0.062 13.1 0.7 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 KND86719.1 - 1.3e-67 227.9 17.2 1.3e-67 227.9 11.9 1.6 1 1 1 2 2 2 1 Pex19 protein family ABC1 PF03109.11 KND86720.1 - 2.1e-32 111.5 0.0 3.6e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DnaJ PF00226.26 KND86721.1 - 8.4e-10 38.2 0.1 1.5e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 KND86722.1 - 3.3e-61 206.9 0.2 5.7e-61 206.2 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 KND86723.1 - 6e-69 232.3 0.0 8e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KND86723.1 - 9e-38 128.8 0.0 1.4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KND86723.1 - 2.7e-29 101.7 0.0 6.1e-29 100.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KND86723.1 - 5.2e-09 35.6 0.0 9.2e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KND86723.1 - 0.00057 18.8 0.0 0.0016 17.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KND86723.1 - 0.0021 16.8 0.0 0.037 12.7 0.0 2.3 1 1 1 2 2 2 1 Glutamine amidotransferases class-II IF3_C PF00707.17 KND86724.1 - 3e-12 46.0 0.0 4.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KND86724.1 - 0.00073 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 KND86724.1 - 0.13 12.1 0.4 0.36 10.7 0.2 1.7 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Peptidase_S26 PF10502.4 KND86725.1 - 2.3e-05 23.9 0.0 0.00039 19.9 0.0 2.3 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KND86725.1 - 4.8e-05 22.9 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_M14 PF00246.19 KND86726.1 - 3.8e-75 253.0 0.0 4.3e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Thymidylate_kin PF02223.12 KND86727.1 - 2e-41 141.3 0.0 3.5e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KND86727.1 - 1.6e-05 24.9 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND86727.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 KND86727.1 - 0.052 13.1 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arf PF00025.16 KND86727.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family OPT PF03169.10 KND86728.1 - 5e-174 580.1 48.6 5.8e-174 579.9 33.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4051 PF13260.1 KND86728.1 - 0.053 12.8 1.1 0.21 10.9 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF4191 PF13829.1 KND86728.1 - 0.1 11.7 0.2 0.34 9.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1418 PF07214.7 KND86728.1 - 6.3 6.4 5.6 14 5.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Formyl_trans_N PF00551.14 KND86729.1 - 7e-38 129.9 0.1 9.3e-38 129.5 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KND86729.1 - 2.7e-09 36.2 0.0 8.9e-09 34.6 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 KND86729.1 - 1.2e-05 24.8 0.0 5.8e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 ACT domain SRP54 PF00448.17 KND86730.1 - 1.3e-77 259.6 1.0 1.3e-77 259.6 0.7 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KND86730.1 - 3.2e-25 88.4 7.2 3.2e-25 88.4 5.0 4.2 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 KND86730.1 - 1.7e-15 56.8 0.6 4.5e-15 55.4 0.4 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KND86730.1 - 5.2e-09 35.8 0.0 1.5e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KND86730.1 - 1.3e-07 31.5 0.1 3.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KND86730.1 - 2.1e-05 24.2 0.0 6.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KND86730.1 - 2.5e-05 23.7 0.1 0.0001 21.7 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KND86730.1 - 3.2e-05 24.7 0.0 7.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND86730.1 - 0.00023 20.3 0.0 0.00047 19.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KND86730.1 - 0.00047 19.0 0.3 0.0031 16.3 0.2 2.2 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 KND86730.1 - 0.0007 19.6 0.1 0.0023 17.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_31 PF13614.1 KND86730.1 - 0.00073 19.4 0.0 1.6 8.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 KND86730.1 - 0.0016 18.6 0.1 0.0059 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 KND86730.1 - 0.0021 17.7 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.1 KND86730.1 - 0.0043 17.0 0.1 0.0091 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KND86730.1 - 0.0056 16.0 0.2 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase SRPRB PF09439.5 KND86730.1 - 0.0068 15.6 0.3 1.7 7.8 0.4 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KND86730.1 - 0.0073 15.8 0.4 0.036 13.6 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KND86730.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 KND86730.1 - 0.0095 15.8 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 1 Torsin 6PF2K PF01591.13 KND86730.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 KND86730.1 - 0.016 15.1 0.0 0.16 11.9 0.0 2.4 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 KND86730.1 - 0.021 14.5 0.1 0.067 12.9 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KND86730.1 - 0.087 12.6 0.4 1.9 8.2 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 KND86730.1 - 0.089 12.9 0.3 0.37 10.9 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KND86730.1 - 0.09 12.4 1.6 4.7 6.8 1.1 2.4 1 1 0 1 1 1 0 NTPase VirE PF05272.6 KND86730.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E Glyco_transf_4 PF13439.1 KND86730.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA_25 PF13481.1 KND86730.1 - 0.12 11.7 0.2 0.67 9.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF3786 PF12654.2 KND86730.1 - 0.16 11.2 0.8 7.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Fungal_trans PF04082.13 KND86731.1 - 2.4e-11 42.9 0.4 8.8e-11 41.1 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C58 PF03543.9 KND86731.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen adh_short PF00106.20 KND86732.1 - 2.1e-28 99.3 1.1 2.6e-28 99.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND86732.1 - 2.4e-20 73.3 0.0 3.2e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND86732.1 - 3.9e-12 46.1 0.7 5.5e-12 45.7 0.5 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 KND86732.1 - 0.012 15.4 0.8 0.023 14.5 0.5 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PepX_C PF08530.5 KND86733.1 - 1.1e-12 48.2 0.0 3.7e-12 46.5 0.0 1.9 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 KND86733.1 - 8e-09 35.3 0.1 2.7e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) TPP_enzyme_N PF02776.13 KND86735.1 - 6.5e-24 84.3 0.0 2.9e-23 82.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KND86735.1 - 4.5e-23 81.5 0.0 9.7e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KND86735.1 - 7.2e-12 45.1 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_18 PF00704.23 KND86736.1 - 7.8e-08 32.1 0.0 8.2e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pyr_redox_2 PF07992.9 KND86737.1 - 8.2e-08 32.3 0.0 1.3e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND86737.1 - 0.00031 20.5 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KND86737.1 - 0.0024 16.8 0.1 0.0056 15.6 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND86737.1 - 0.013 15.6 0.0 0.29 11.1 0.1 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND86737.1 - 0.1 11.5 0.0 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KND86737.1 - 0.16 10.8 0.1 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KND86737.1 - 0.19 10.5 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lactamase_B PF00753.22 KND86738.1 - 3e-19 69.4 4.5 4.3e-19 68.9 3.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND86738.1 - 6.5e-05 22.5 0.3 9.2e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KND86738.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF4141 PF13605.1 KND86738.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Ribosomal_L14 PF00238.14 KND86739.1 - 1.1e-42 144.6 1.3 1.2e-42 144.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.11 KND86739.1 - 0.015 14.8 0.2 0.026 14.1 0.1 1.5 1 1 0 1 1 1 0 Flagellar L-ring protein TFIIS_C PF01096.13 KND86740.1 - 1.7e-16 59.5 5.0 1.7e-16 59.5 3.4 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KND86740.1 - 7.9e-12 44.6 2.7 7.9e-12 44.6 1.9 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 KND86740.1 - 0.046 14.0 9.7 0.11 12.8 1.8 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.8 KND86740.1 - 0.14 11.8 9.2 0.43 10.2 0.6 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2296 PF10058.4 KND86740.1 - 0.14 11.9 11.0 0.39 10.4 0.2 2.9 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 KND86740.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 KND86740.1 - 0.74 9.6 18.5 0.05 13.4 2.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KND86740.1 - 0.78 9.5 15.7 0.22 11.3 3.5 2.9 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.1 KND86740.1 - 0.86 9.3 14.7 0.18 11.5 0.8 3.5 4 0 0 4 4 4 0 Nudix N-terminal Mut7-C PF01927.11 KND86740.1 - 1.3 9.0 7.4 1.7 8.5 2.5 2.1 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-RING_3 PF14369.1 KND86740.1 - 1.5 8.8 12.0 2.9 7.9 0.2 3.2 3 0 0 3 3 3 0 zinc-finger C1_4 PF07975.7 KND86740.1 - 2.3 8.2 14.7 1.2 9.2 1.9 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain IBR PF01485.16 KND86740.1 - 3.3 7.6 15.6 3.3e+03 -2.0 10.8 2.6 1 1 0 1 1 1 0 IBR domain Pkinase_Tyr PF07714.12 KND86741.1 - 7e-18 64.6 0.0 2.2e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND86741.1 - 1.3e-15 57.2 0.0 2.8e-15 56.1 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain PSI_PSAK PF01241.13 KND86741.1 - 0.0019 18.1 0.0 0.99 9.4 0.0 2.3 2 0 0 2 2 2 2 Photosystem I psaG / psaK Kdo PF06293.9 KND86741.1 - 0.031 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 KND86741.1 - 0.038 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kinase-like PF14531.1 KND86741.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAP2_3 PF14378.1 KND86742.1 - 5.2e-23 81.5 11.9 8.3e-18 64.5 1.5 2.4 3 0 0 3 3 3 2 PAP2 superfamily PAP2_C PF14360.1 KND86742.1 - 0.059 13.6 5.4 0.18 12.1 0.1 2.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF2537 PF10801.3 KND86742.1 - 0.62 10.2 3.8 0.29 11.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) SET PF00856.23 KND86743.1 - 5.4e-09 36.5 0.0 3.2e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 SET domain SKG6 PF08693.5 KND86745.1 - 3.8e-07 29.2 0.8 9.1e-07 28.0 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 KND86745.1 - 0.0022 16.7 3.4 0.0022 16.7 2.3 2.3 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF4381 PF14316.1 KND86745.1 - 0.036 14.1 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF202 PF02656.10 KND86745.1 - 0.044 13.9 1.3 0.14 12.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4349 PF14257.1 KND86745.1 - 0.046 12.9 0.6 0.069 12.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4448 PF14610.1 KND86745.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2029 PF09594.5 KND86745.1 - 1.2 8.5 6.8 2.9 7.3 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) PseudoU_synth_1 PF01416.15 KND86746.1 - 1.9e-22 79.6 0.2 9.9e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ank_2 PF12796.2 KND86748.1 - 4.8e-44 148.6 6.1 9.7e-20 70.7 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KND86748.1 - 4.8e-39 130.2 9.1 1.4e-08 34.1 0.0 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KND86748.1 - 6.7e-30 102.9 1.4 7.8e-11 42.1 0.0 6.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86748.1 - 1.8e-25 86.4 3.9 1.7e-05 24.6 0.0 9.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 KND86748.1 - 1.6e-21 75.8 11.5 2.5e-08 33.8 0.0 8.7 3 2 6 9 9 9 5 Ankyrin repeats (many copies) AAA_16 PF13191.1 KND86748.1 - 7.5e-05 22.7 0.2 0.00051 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KND86748.1 - 0.0054 16.4 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Beta_elim_lyase PF01212.16 KND86750.1 - 1.9e-66 224.1 0.6 2.5e-66 223.7 0.4 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KND86750.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KND86750.1 - 0.01 14.1 0.1 0.019 13.2 0.1 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme APH PF01636.18 KND86751.1 - 1.3e-13 51.2 0.1 2.1e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KND86751.1 - 0.00019 20.6 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND86751.1 - 0.00032 19.9 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.15 KND86751.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND86751.1 - 0.0041 16.5 0.0 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Med22 PF06179.7 KND86752.1 - 8.1e-06 25.8 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3357 PF11837.3 KND86753.1 - 0.0027 17.5 0.6 0.0057 16.4 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3357) DUF912 PF06024.7 KND86753.1 - 0.0043 17.0 0.6 0.01 15.9 0.2 1.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) AA_permease_2 PF13520.1 KND86753.1 - 0.037 12.5 0.0 0.067 11.7 0.0 1.4 2 0 0 2 2 2 0 Amino acid permease Neur_chan_memb PF02932.11 KND86753.1 - 0.039 13.8 0.1 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Protocadherin PF08374.6 KND86753.1 - 0.054 13.1 5.1 0.23 11.0 0.5 2.2 1 1 1 2 2 2 0 Protocadherin SDF PF00375.13 KND86753.1 - 0.075 11.7 0.3 0.08 11.6 0.2 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Mucin PF01456.12 KND86753.1 - 0.34 10.6 12.2 0.39 10.4 7.9 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein FAM195 PF14799.1 KND86753.1 - 0.92 9.4 4.0 0.36 10.7 0.7 1.9 2 1 0 2 2 2 0 FAM195 family LIP PF03583.9 KND86754.1 - 0.023 13.8 0.0 0.025 13.7 0.0 1.0 1 0 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.13 KND86754.1 - 0.084 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PXPV PF12778.2 KND86754.1 - 0.4 10.3 5.7 1 9.0 3.0 2.0 2 0 0 2 2 2 0 PXPV repeat (3 copies) MFS_1 PF07690.11 KND86755.1 - 7.2e-23 80.8 35.0 7.2e-23 80.8 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86755.1 - 4.4e-13 48.6 16.9 4.4e-13 48.6 11.7 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.2 KND86756.1 - 8e-78 256.8 0.4 4.7e-13 49.2 0.0 7.7 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KND86756.1 - 3.4e-52 171.7 8.9 4.5e-05 23.0 0.0 15.6 14 1 1 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 KND86756.1 - 1.1e-37 127.7 2.2 0.0008 19.8 0.0 12.1 9 3 4 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND86756.1 - 4.7e-37 125.1 6.2 8.9e-05 22.6 0.1 11.7 7 5 5 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86756.1 - 4.7e-36 119.2 4.0 0.0028 17.7 0.0 14.7 16 0 0 16 16 16 9 Ankyrin repeat Shigella_OspC PF06128.6 KND86756.1 - 0.035 13.6 0.1 53 3.1 0.0 4.3 4 1 1 5 5 5 0 Shigella flexneri OspC protein MOZART1 PF12554.3 KND86756.1 - 0.036 13.5 3.4 6.5 6.3 0.0 5.1 7 0 0 7 7 7 0 Mitotic-spindle organizing gamma-tubulin ring associated FCD PF07729.7 KND86756.1 - 0.063 13.6 0.1 5.6 7.3 0.0 3.7 3 1 1 4 4 4 0 FCD domain RVT_2 PF07727.9 KND86757.1 - 1.5e-06 27.3 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.18 KND86758.1 - 2.9e-06 27.1 1.4 1e-05 25.3 1.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86758.1 - 0.043 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myco_arth_vir_N PF09610.5 KND86761.1 - 0.24 11.3 0.3 0.45 10.5 0.2 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF3584 PF12128.3 KND86763.1 - 0.06 10.6 0.2 0.064 10.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Surface_antigen PF11054.3 KND86763.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Abhydrolase_6 PF12697.2 KND86764.1 - 4.1e-13 49.7 0.0 6.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND86764.1 - 1.2e-09 38.0 0.0 4.1e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND86764.1 - 5.4e-05 22.8 0.0 8.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KND86764.1 - 0.00089 19.0 0.0 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Sugar_tr PF00083.19 KND86765.1 - 3.4e-78 263.2 26.1 1.3e-52 178.9 3.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KND86765.1 - 1.8e-18 66.4 46.6 8.7e-13 47.6 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transaldolase PF00923.14 KND86766.1 - 2.7e-30 105.5 0.0 4.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Transaldolase Beta-lactamase PF00144.19 KND86767.1 - 5.1e-47 160.5 0.1 7.6e-47 159.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KND86767.1 - 0.019 14.8 0.0 0.049 13.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3471) Acetyltransf_1 PF00583.19 KND86768.1 - 7e-14 51.6 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND86768.1 - 8.8e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND86768.1 - 5e-07 29.8 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND86768.1 - 5.2e-05 22.9 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KND86768.1 - 8.6e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KND86768.1 - 8.9e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND86768.1 - 0.00043 20.1 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND86768.1 - 0.046 13.8 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KND86769.1 - 3.1e-31 108.3 37.5 4.4e-31 107.8 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND86769.1 - 6.9e-11 41.3 23.6 1.4e-10 40.3 16.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 KND86769.1 - 8.1e-06 24.5 9.3 8.1e-06 24.5 6.5 2.8 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KND86769.1 - 0.18 11.5 0.1 0.18 11.5 0.1 3.2 3 1 0 3 3 3 0 MFS_1 like family Bestrophin PF01062.16 KND86770.1 - 1.1e-47 162.3 1.6 1.4e-45 155.5 1.1 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel VIT1 PF01988.14 KND86770.1 - 0.0035 16.8 0.6 0.009 15.5 0.0 1.8 2 0 0 2 2 2 1 VIT family Glyoxalase_2 PF12681.2 KND86772.1 - 3.7e-09 37.1 0.0 5.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KND86772.1 - 4e-06 26.8 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M28 PF04389.12 KND86773.1 - 2.9e-25 89.0 0.0 5.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Rotamase PF00639.16 KND86773.1 - 3.4e-20 72.5 0.1 1.1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain PA PF02225.17 KND86773.1 - 1.5e-16 59.8 0.1 4e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 PA domain Rotamase_3 PF13616.1 KND86773.1 - 8.1e-15 55.1 0.0 1.8e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KND86773.1 - 4.4e-06 26.4 0.7 1.4e-05 24.8 0.5 2.0 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 KND86773.1 - 4.5e-05 24.0 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain LrgB PF04172.11 KND86774.1 - 1.3e-13 50.6 9.1 3.9e-08 32.7 0.1 2.8 3 0 0 3 3 3 2 LrgB-like family SKG6 PF08693.5 KND86774.1 - 0.044 13.0 0.3 0.044 13.0 0.2 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3466 PF11949.3 KND86774.1 - 0.2 10.1 0.2 0.29 9.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) SE PF08491.5 KND86775.1 - 1.2e-92 309.6 0.0 1.5e-92 309.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KND86775.1 - 9.9e-15 54.4 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND86775.1 - 4.1e-12 45.6 1.3 2.9e-07 29.7 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 KND86775.1 - 6.4e-05 21.9 0.1 0.045 12.6 0.0 2.0 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KND86775.1 - 9e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND86775.1 - 0.00014 22.1 0.1 0.0062 16.9 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND86775.1 - 0.00019 21.4 0.5 0.00039 20.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KND86775.1 - 0.00043 19.9 0.1 0.00071 19.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KND86775.1 - 0.00072 18.7 0.1 0.0018 17.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KND86775.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KND86775.1 - 0.0022 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KND86775.1 - 0.003 16.5 0.1 0.022 13.6 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KND86775.1 - 0.0039 16.9 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 KND86775.1 - 0.013 14.4 2.4 0.014 14.3 0.5 1.8 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KND86775.1 - 0.025 13.2 0.1 1.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 KND86775.1 - 0.029 13.8 0.1 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KND86775.1 - 0.07 13.5 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KND86775.1 - 0.11 12.3 0.5 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 KND86775.1 - 0.13 10.6 0.1 0.22 9.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.10 KND86775.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.20 KND86776.1 - 4.6e-13 48.9 0.0 5.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND86776.1 - 1.5e-06 27.4 0.0 2.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KND86776.1 - 1.2e-05 24.5 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND86776.1 - 2.2e-05 24.3 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND86776.1 - 0.0044 16.3 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KND86776.1 - 0.0077 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KND86776.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 KND86776.1 - 0.058 12.3 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EcKinase PF02958.15 KND86776.1 - 0.063 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Seadorna_VP7 PF07387.6 KND86776.1 - 0.13 11.1 0.1 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4061 PF13270.1 KND86777.1 - 6.2 6.9 9.4 4.9 7.3 2.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) Kinesin-relat_1 PF12711.2 KND86777.1 - 8.5 6.8 14.0 2.5 8.5 2.1 4.2 4 1 0 4 4 4 0 Kinesin motor APH PF01636.18 KND86779.1 - 4e-05 23.4 0.1 6.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KND86780.1 - 1.9e-09 37.5 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND86780.1 - 0.026 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EBP PF05241.7 KND86781.1 - 8.5e-66 220.6 10.7 1.1e-65 220.3 7.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein Glyco_hydro_31 PF01055.21 KND86782.1 - 2.3e-72 244.2 0.0 2.8e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KND86782.1 - 1.8e-07 30.8 0.0 4.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like p450 PF00067.17 KND86783.1 - 2.1e-36 125.4 0.0 7.6e-26 90.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Maff2 PF12750.2 KND86784.1 - 0.068 12.7 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Maff2 family MFS_1 PF07690.11 KND86785.1 - 2e-31 108.9 30.6 2e-31 108.9 21.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PspB PF06667.7 KND86785.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.0 2 0 0 2 2 2 0 Phage shock protein B Phage_GP20 PF06810.6 KND86787.1 - 0.00022 20.6 3.1 0.00022 20.6 2.2 4.5 3 1 2 5 5 5 2 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 KND86787.1 - 1.2 8.2 17.1 8.9 5.3 0.3 4.1 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Mpv17_PMP22 PF04117.7 KND86788.1 - 2.1e-16 59.3 0.3 2.1e-16 59.3 0.2 2.1 2 1 0 2 2 2 1 Mpv17 / PMP22 family NAD_binding_2 PF03446.10 KND86789.1 - 2e-27 96.0 0.4 3.2e-27 95.3 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KND86789.1 - 3e-09 37.0 0.3 5.4e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KND86789.1 - 3.7e-06 27.2 0.0 1.1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KND86789.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 KND86790.1 - 6.7e-06 25.1 0.0 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86790.1 - 0.1 12.5 5.4 0.39 10.6 3.7 2.1 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KND86790.1 - 0.21 11.7 3.1 0.58 10.3 2.1 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Na_H_Exchanger PF00999.16 KND86791.1 - 1.4e-05 23.8 0.2 2.1e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DNA_pol_A_exo1 PF01612.15 KND86793.1 - 2.4e-42 144.3 0.1 3.5e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KND86793.1 - 5.4e-23 81.1 0.0 1e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KND86793.1 - 2.5e-09 36.7 0.0 5.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Nop14 PF04147.7 KND86793.1 - 6.3 4.5 13.6 10 3.8 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_20 PF00982.16 KND86794.1 - 7.7e-198 657.7 0.0 9.1e-198 657.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KND86794.1 - 0.04 13.3 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain TFIID_20kDa PF03847.8 KND86795.1 - 8.9e-19 67.5 0.0 1.5e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Rpn3_C PF08375.6 KND86796.1 - 1e-24 86.6 1.4 2.9e-24 85.2 1.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KND86796.1 - 2e-19 69.8 0.1 5.6e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KND86796.1 - 0.014 15.3 1.6 0.022 14.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.1 KND86797.1 - 6e-15 53.5 1.1 0.056 13.5 0.0 6.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 KND86797.1 - 0.00055 19.4 0.0 5.1 6.8 0.0 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KND86797.1 - 0.058 13.4 1.9 87 3.7 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat VID27 PF08553.5 KND86798.1 - 0 1087.5 0.0 0 1087.4 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein RTA1 PF04479.8 KND86799.1 - 7.3e-10 38.7 2.2 7.3e-10 38.7 1.5 1.4 2 0 0 2 2 2 1 RTA1 like protein Flavodoxin_4 PF12682.2 KND86799.1 - 0.021 14.1 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Flavodoxin Ank_2 PF12796.2 KND86800.1 - 1.3e-18 67.0 2.9 3.1e-11 43.4 0.9 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND86800.1 - 8.7e-15 53.6 7.5 5.1e-05 22.8 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KND86800.1 - 1.3e-11 44.3 7.6 0.0002 21.4 0.2 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND86800.1 - 1.3e-11 43.5 5.2 0.00016 21.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Cupin_1 PF00190.17 KND86800.1 - 4e-11 42.5 0.1 8.1e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Cupin Ank_4 PF13637.1 KND86800.1 - 7.9e-11 42.1 8.9 5.1e-06 26.8 0.3 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Cupin_2 PF07883.6 KND86800.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Prok_Ub PF14454.1 KND86800.1 - 0.087 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Ribosomal_S26e PF01283.14 KND86802.1 - 4e-49 165.6 9.3 4.5e-49 165.4 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KND86802.1 - 0.098 13.0 2.4 1.1 9.6 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1918 PF08940.6 KND86802.1 - 0.11 11.9 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Adeno_GP19K PF04881.8 KND86802.1 - 0.11 12.2 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus GP19K Zn_ribbon_2 PF12674.2 KND86802.1 - 0.11 12.8 0.6 9.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Ribosomal_S27 PF01599.14 KND86803.1 - 1.5e-27 95.0 1.2 1.5e-27 95.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.18 KND86803.1 - 0.015 14.7 0.1 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family IBR PF01485.16 KND86803.1 - 0.12 12.3 0.7 0.16 11.8 0.5 1.4 1 1 0 1 1 1 0 IBR domain Nop PF01798.13 KND86804.1 - 4e-54 181.9 0.1 8.7e-54 180.8 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KND86804.1 - 1.8e-23 82.0 0.1 3.8e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KND86804.1 - 8.5e-20 70.6 0.1 8.5e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 KND86804.1 - 3 7.4 23.2 5.7 6.5 16.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_18 PF00704.23 KND86805.1 - 3.1e-94 316.2 3.9 3.5e-94 316.0 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BcrAD_BadFG PF01869.15 KND86806.1 - 1.3e-18 67.3 0.2 2.7e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.17 KND86806.1 - 0.0026 17.3 0.7 0.019 14.5 0.0 2.4 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KND86806.1 - 0.0071 16.0 0.4 0.15 11.7 0.1 3.2 3 1 0 3 3 3 1 SIS domain HtaA PF04213.8 KND86806.1 - 0.12 12.6 0.1 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Htaa UNC-93 PF05978.11 KND86807.1 - 9.5e-09 34.9 5.7 9.5e-09 34.9 4.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KND86807.1 - 2.2e-07 29.9 39.8 2.2e-07 29.9 27.6 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily ELYS PF13934.1 KND86808.1 - 1.2e-61 208.2 0.3 1.6e-61 207.9 0.2 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly ATP-synt_C PF00137.16 KND86809.1 - 1e-15 57.3 10.9 1.7e-15 56.6 7.6 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF1469 PF07332.6 KND86809.1 - 0.72 9.5 7.3 1.7 8.4 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) MOZ_SAS PF01853.13 KND86810.1 - 7.7e-47 158.9 0.0 1.5e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family APH PF01636.18 KND86811.1 - 0.0079 15.9 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF761 PF05553.6 KND86811.1 - 0.21 10.9 1.5 0.32 10.4 0.3 1.8 2 0 0 2 2 2 0 Cotton fibre expressed protein Arginase PF00491.16 KND86813.1 - 5.1e-76 255.6 0.5 6e-76 255.3 0.4 1.0 1 0 0 1 1 1 1 Arginase family Amdo_NSP PF12475.3 KND86813.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Amdovirus non-structural protein MARVEL PF01284.18 KND86815.1 - 0.0017 18.2 10.0 0.0044 16.8 7.0 1.9 1 1 0 1 1 1 1 Membrane-associating domain Amidohydro_1 PF01979.15 KND86816.1 - 1.1e-18 68.0 0.9 6.6e-16 58.8 0.6 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KND86816.1 - 1e-17 65.1 3.8 1.5e-17 64.5 2.7 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KND86816.1 - 2.2e-10 40.1 0.0 4.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KND86816.1 - 8e-06 25.3 5.2 0.0015 17.7 0.0 2.8 2 1 1 3 3 3 2 Amidohydrolase family SMC_N PF02463.14 KND86817.1 - 3.2e-36 124.6 7.9 5.5e-36 123.8 5.4 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KND86817.1 - 2.9e-25 88.5 0.0 6.7e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KND86817.1 - 4.8e-06 26.7 0.5 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain IncA PF04156.9 KND86817.1 - 1.1e-05 25.1 56.0 5.2e-05 22.9 6.3 5.1 3 1 2 5 5 5 3 IncA protein TPR_MLP1_2 PF07926.7 KND86817.1 - 0.00015 21.4 58.5 0.0037 17.0 6.0 5.9 2 2 2 4 4 4 3 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 KND86817.1 - 0.00028 20.7 8.1 0.00028 20.7 5.6 5.6 3 1 3 6 6 5 2 Tropomyosin like Fib_alpha PF08702.5 KND86817.1 - 0.00092 19.3 4.2 0.00092 19.3 2.9 4.6 4 1 0 5 5 5 1 Fibrinogen alpha/beta chain family WEMBL PF05701.6 KND86817.1 - 0.0012 17.4 36.3 0.0012 17.4 25.1 3.7 2 1 2 4 4 3 1 Weak chloroplast movement under blue light IFT57 PF10498.4 KND86817.1 - 0.0012 17.6 8.1 0.0012 17.6 5.6 3.9 2 1 2 5 5 5 2 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 KND86817.1 - 0.0014 17.9 6.6 0.051 12.7 0.5 3.4 2 1 3 5 5 5 2 Reovirus sigma C capsid protein GAS PF13851.1 KND86817.1 - 0.0027 16.9 5.4 0.0027 16.9 3.8 5.5 3 1 3 6 6 5 1 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KND86817.1 - 0.0028 17.0 1.9 0.0028 17.0 1.3 7.4 5 2 4 9 9 7 1 Septum formation initiator SbcCD_C PF13558.1 KND86817.1 - 0.0074 16.1 0.0 0.084 12.8 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Spc7 PF08317.6 KND86817.1 - 0.032 12.8 55.8 0.025 13.2 8.0 4.1 3 1 1 4 4 4 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 KND86817.1 - 0.039 13.7 0.6 0.039 13.7 0.4 7.3 3 1 5 8 8 7 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 KND86817.1 - 0.14 11.6 53.2 0.04 13.3 28.6 4.4 3 1 0 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 KND86817.1 - 0.24 9.8 41.6 0.0038 15.7 12.9 3.1 1 1 1 2 2 2 0 AAA domain DUF2937 PF11157.3 KND86817.1 - 1.2 8.4 10.0 0.73 9.1 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF1664 PF07889.7 KND86817.1 - 1.7 8.4 26.0 0.79 9.5 3.4 5.3 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KND86817.1 - 1.9 8.8 41.9 2.1 8.7 0.1 6.0 3 1 2 5 5 5 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 KND86817.1 - 2.5 8.4 19.9 11 6.3 0.3 6.1 2 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 KND86817.1 - 4.7 7.1 20.4 4.3 7.3 0.7 5.5 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) Plasmid_stabil PF05016.9 KND86817.1 - 7.7 6.9 8.5 16 6.0 2.0 3.8 3 1 0 3 3 2 0 Plasmid stabilisation system protein Vma12 PF11712.3 KND86818.1 - 2.4e-35 121.3 0.0 3.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase polyprenyl_synt PF00348.12 KND86819.1 - 1.1e-54 185.0 0.0 2e-51 174.3 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KND86819.1 - 0.0041 16.5 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Sugar_tr PF00083.19 KND86820.1 - 4.5e-61 206.7 14.4 8e-61 205.9 9.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KND86820.1 - 4.5e-06 25.6 22.5 8.2e-05 21.4 12.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily zf-C2H2_3 PF13878.1 KND86821.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Microtub_assoc PF07989.6 KND86823.1 - 8.7e-20 70.3 11.4 8.7e-20 70.3 7.9 7.8 9 0 0 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 KND86823.1 - 3.7e-11 42.9 11.6 3.7e-11 42.9 8.0 12.4 12 1 0 12 12 12 1 Micro-tubular organiser Mto1 C-term Mto2-binding region NPV_P10 PF05531.7 KND86823.1 - 0.05 13.8 21.2 0.34 11.1 0.1 6.0 6 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KND86823.1 - 0.64 10.1 66.1 0.23 11.5 4.5 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KND86823.1 - 4.4 6.3 38.4 0.15 11.2 2.2 6.1 5 1 0 6 6 6 0 Reovirus sigma C capsid protein AHS1 PF02682.11 KND86823.1 - 7.3 5.9 6.2 7.4 5.9 0.2 3.1 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 DUF1479 PF07350.7 KND86824.1 - 2.7e-160 533.4 0.0 3.1e-160 533.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KND86824.1 - 0.00051 20.1 0.2 0.76 9.7 0.1 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1993 PF09351.5 KND86825.1 - 2e-46 157.9 0.0 2.2e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF2697 PF10906.3 KND86826.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) DeoC PF01791.4 KND86828.1 - 1.6e-34 119.2 0.9 1.9e-34 119.0 0.6 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase ETC_C1_NDUFA5 PF04716.9 KND86829.1 - 8.2e-20 70.0 1.5 8.9e-20 69.9 0.0 1.9 2 0 0 2 2 2 1 ETC complex I subunit conserved region Dynamitin PF04912.9 KND86829.1 - 0.059 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Dynamitin BAR_2 PF10455.4 KND86830.1 - 5.7e-56 189.5 0.5 8.3e-56 189.0 0.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KND86830.1 - 6.3e-19 68.4 2.8 2.6e-17 63.1 1.9 2.1 1 1 0 1 1 1 1 BAR domain APH PF01636.18 KND86831.1 - 4.2e-12 46.3 0.0 5.8e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86831.1 - 7.6e-07 28.9 0.1 1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KND86831.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KND86831.1 - 0.063 12.4 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 KND86831.1 - 0.076 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF619 PF04768.8 KND86832.1 - 1.4e-53 180.7 0.0 1.7e-52 177.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF619) IQ PF00612.22 KND86833.1 - 0.078 12.6 0.5 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fungal_trans PF04082.13 KND86835.1 - 5.6e-38 130.2 0.1 4.1e-37 127.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86835.1 - 5.7e-08 32.5 8.3 9.8e-08 31.7 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.9 KND86836.1 - 3.7e-159 530.0 28.0 4.7e-159 529.7 19.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KND86836.1 - 8.1e-10 38.5 0.5 3e-09 36.6 0.3 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KND86836.1 - 5.7e-09 35.5 0.4 1.4e-08 34.3 0.1 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KND86836.1 - 2.5e-05 23.8 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3975 PF13126.1 KND86836.1 - 0.24 11.5 6.7 0.2 11.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3975) NAD_binding_2 PF03446.10 KND86837.1 - 1.7e-28 99.5 0.0 3.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP_synt_H PF05493.8 KND86837.1 - 5e-19 68.1 5.4 1.5e-15 56.9 0.3 2.6 2 0 0 2 2 2 2 ATP synthase subunit H F420_oxidored PF03807.12 KND86837.1 - 2.2e-10 40.7 0.1 1.1e-09 38.6 0.0 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KND86837.1 - 4.8e-09 36.3 0.2 9.6e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KND86837.1 - 3.3e-08 33.7 0.0 7.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KND86837.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain OCD_Mu_crystall PF02423.10 KND86837.1 - 0.022 13.5 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family KR PF08659.5 KND86837.1 - 0.037 13.7 0.2 0.11 12.1 0.0 1.8 2 1 0 2 2 2 0 KR domain Cren7 PF11520.3 KND86837.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin protein Cren7 GFO_IDH_MocA PF01408.17 KND86837.1 - 0.1 13.1 0.0 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Renin_r PF07850.9 KND86837.1 - 0.1 12.9 0.2 0.3 11.4 0.2 1.7 1 0 0 1 1 1 0 Renin receptor-like protein Arv1 PF04161.8 KND86838.1 - 8.1e-40 136.9 0.0 1.2e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.15 KND86838.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 LysM domain Abhydrolase_3 PF07859.8 KND86839.1 - 4.1e-47 160.4 0.2 5.3e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KND86839.1 - 5.6e-05 22.0 0.0 0.00012 20.9 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KND86839.1 - 0.0016 18.1 0.1 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 KND86840.1 - 6.9e-60 202.6 0.2 8.9e-60 202.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86840.1 - 8.9e-05 22.3 15.5 0.00015 21.5 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM240 PF15207.1 KND86840.1 - 0.07 12.6 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 TMEM240 family Collagen PF01391.13 KND86840.1 - 3.4 7.3 6.0 5.6 6.5 4.1 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) FAD_binding_3 PF01494.14 KND86841.1 - 9.8e-18 64.3 0.0 1.3e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KND86841.1 - 7.7e-08 32.2 1.6 2.4e-07 30.6 1.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND86841.1 - 1.6e-06 27.2 0.8 2.5e-06 26.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND86841.1 - 2.1e-06 26.8 4.0 4.3e-06 25.8 1.5 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND86841.1 - 3.6e-05 23.7 0.8 6.8e-05 22.8 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND86841.1 - 9.3e-05 21.6 1.4 0.00014 21.0 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND86841.1 - 0.00069 19.9 0.3 0.0017 18.7 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KND86841.1 - 0.0031 16.4 0.3 0.0046 15.8 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KND86841.1 - 0.0043 17.1 0.2 0.0081 16.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND86841.1 - 0.0088 15.1 0.4 0.016 14.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 KND86841.1 - 0.0097 15.0 0.2 0.018 14.1 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KND86841.1 - 0.019 13.6 0.0 0.059 12.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KND86841.1 - 0.023 13.6 0.1 0.048 12.5 0.1 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KND86841.1 - 0.028 12.8 0.4 0.04 12.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KND86841.1 - 0.041 13.6 0.1 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KND86841.1 - 0.087 12.3 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KND86841.1 - 0.18 11.5 0.5 0.35 10.6 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Epimerase PF01370.16 KND86843.1 - 1.4e-23 83.5 0.2 3e-23 82.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND86843.1 - 2.7e-11 42.8 0.0 8.4e-10 37.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KND86843.1 - 2.4e-10 40.7 0.0 4.2e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND86843.1 - 2.7e-10 39.4 0.0 8.4e-10 37.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KND86843.1 - 0.00049 19.0 0.0 0.00091 18.2 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KND86843.1 - 0.003 16.8 0.0 0.015 14.5 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KND86843.1 - 0.015 15.2 0.6 0.015 15.2 0.4 1.8 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KND86843.1 - 0.018 13.9 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 KND86844.1 - 2.2e-18 66.0 1.0 3.1e-18 65.5 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86844.1 - 0.00038 20.3 11.4 0.00064 19.5 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KND86845.1 - 2.7e-73 247.0 20.6 3.2e-73 246.8 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND86845.1 - 9.4e-22 77.1 32.4 2.7e-20 72.4 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.7 KND86845.1 - 0.00049 18.6 0.6 0.00049 18.6 0.4 1.9 2 0 0 2 2 2 1 Ferroportin1 (FPN1) UPF0075 PF03702.9 KND86846.1 - 2.2e-85 286.7 0.0 2.6e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF3140 PF11338.3 KND86847.1 - 2.5e-18 65.9 0.4 2.5e-18 65.9 0.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) DUF2945 PF11160.3 KND86847.1 - 0.039 13.7 0.7 0.039 13.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2945) AMP-binding PF00501.23 KND86848.1 - 2.8e-136 454.2 0.2 1.8e-85 286.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KND86848.1 - 1.5e-83 280.0 0.0 2.1e-42 145.0 0.0 2.9 3 0 0 3 3 3 2 Condensation domain MFS_1 PF07690.11 KND86848.1 - 2.1e-33 115.5 31.8 6.7e-33 113.8 22.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PP-binding PF00550.20 KND86848.1 - 1.4e-25 89.2 1.7 4.4e-12 46.0 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KND86848.1 - 6.1e-07 30.2 0.0 0.1 13.5 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF3105 PF11303.3 KND86848.1 - 0.021 14.6 0.4 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) Pescadillo_N PF06732.6 KND86848.1 - 0.14 11.4 0.2 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Pescadillo N-terminus Csm1 PF12539.3 KND86849.1 - 3.8e-25 88.1 0.0 6.6e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 PspA_IM30 PF04012.7 KND86849.1 - 0.0008 18.8 12.3 0.0008 18.8 8.5 1.6 2 0 0 2 2 2 1 PspA/IM30 family Rootletin PF15035.1 KND86849.1 - 0.0013 18.7 9.4 0.0025 17.8 6.5 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion EzrA PF06160.7 KND86849.1 - 0.0096 14.1 3.2 0.014 13.6 2.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.6 KND86849.1 - 0.012 14.3 8.0 0.018 13.7 5.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 KND86849.1 - 0.14 12.0 11.5 0.12 12.3 6.6 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 KND86849.1 - 0.16 10.3 2.8 0.24 9.8 1.9 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 KND86849.1 - 0.19 10.6 8.2 0.36 9.7 5.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 KND86849.1 - 0.23 11.3 11.5 0.46 10.3 2.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KND86849.1 - 0.35 10.0 9.8 0.39 9.8 1.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KND86849.1 - 0.49 9.9 13.9 5 6.6 4.7 2.3 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 KND86849.1 - 0.68 8.2 3.8 1 7.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KND86849.1 - 1.4 9.0 4.5 2.9 7.9 3.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 KND86849.1 - 1.8 8.6 8.8 2.8 8.0 5.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 KND86849.1 - 1.8 7.5 8.6 2.7 6.9 5.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AT_hook PF02178.14 KND86849.1 - 2 8.3 7.6 9.4 6.2 2.4 2.8 2 0 0 2 2 2 0 AT hook motif Cep57_CLD_2 PF14197.1 KND86849.1 - 5.2 7.0 12.3 0.086 12.7 2.6 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.3 KND86849.1 - 9.7 6.0 13.7 7 6.5 4.9 2.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding AAA PF00004.24 KND86850.1 - 4.6e-37 127.1 0.0 7.5e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KND86850.1 - 9.8e-06 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND86850.1 - 1.3e-05 25.3 0.3 0.00077 19.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND86850.1 - 2.8e-05 23.8 0.1 0.00027 20.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KND86850.1 - 3e-05 23.1 0.0 6e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND86850.1 - 5.6e-05 23.2 0.3 0.00067 19.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KND86850.1 - 6.1e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KND86850.1 - 0.00015 22.5 0.1 0.00046 21.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KND86850.1 - 0.00074 18.9 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KND86850.1 - 0.00091 19.2 0.0 0.0037 17.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 KND86850.1 - 0.00095 18.3 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 KND86850.1 - 0.00098 18.6 0.0 0.042 13.3 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 KND86850.1 - 0.0011 18.8 1.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KND86850.1 - 0.0015 17.7 0.1 0.0038 16.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KND86850.1 - 0.0042 16.8 0.2 0.017 14.8 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 KND86850.1 - 0.0051 16.2 3.4 0.21 10.9 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 KND86850.1 - 0.011 15.7 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KND86850.1 - 0.011 16.0 2.2 0.045 14.0 0.0 2.5 2 1 1 3 3 2 0 AAA domain RNA_helicase PF00910.17 KND86850.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Oxidored_nitro PF00148.14 KND86850.1 - 0.015 13.9 0.0 0.082 11.5 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase NACHT PF05729.7 KND86850.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 1 0 NACHT domain ABC_tran PF00005.22 KND86850.1 - 0.029 14.6 0.0 0.1 12.8 0.0 2.1 2 1 0 2 2 1 0 ABC transporter DUF815 PF05673.8 KND86850.1 - 0.031 13.1 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 KND86850.1 - 0.074 11.8 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 KND86850.1 - 0.082 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_10 PF12846.2 KND86850.1 - 0.085 12.2 0.7 1.1 8.6 0.1 2.7 3 1 0 3 3 3 0 AAA-like domain AAA_24 PF13479.1 KND86850.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KND86850.1 - 0.12 12.0 0.0 0.63 9.6 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 KND86850.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Guanylate_kin PF00625.16 KND86850.1 - 0.15 11.4 0.0 0.65 9.4 0.0 2.0 2 1 0 2 2 1 0 Guanylate kinase PhoH PF02562.11 KND86850.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SWIRM PF04433.12 KND86851.1 - 5.8e-35 119.2 0.1 1e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KND86851.1 - 1.8e-07 31.0 0.1 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND86851.1 - 3.3e-05 23.8 0.1 7.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KND86851.1 - 0.00012 21.5 4.3 0.00025 20.5 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Fungal_trans PF04082.13 KND86853.1 - 1.5e-13 50.2 0.0 3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KND86853.1 - 1.2e-10 40.8 0.5 1.8e-07 30.3 0.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND86853.1 - 1.2e-07 31.6 1.6 2.3e-07 30.7 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.13 KND86853.1 - 1.9e-05 24.4 7.2 3.9e-05 23.4 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 KND86853.1 - 3.1e-05 23.9 0.1 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND86853.1 - 7e-05 22.0 1.8 0.22 10.5 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KND86853.1 - 0.00036 19.5 0.0 0.00058 18.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KND86853.1 - 0.0004 20.7 0.5 0.0011 19.2 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KND86853.1 - 0.00052 19.2 0.1 0.051 12.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KND86853.1 - 0.0021 17.0 0.2 0.0038 16.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KND86853.1 - 0.0054 15.8 0.1 0.0093 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KND86853.1 - 0.01 14.7 1.0 0.022 13.6 0.7 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.4 KND86853.1 - 0.086 12.5 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Rossmann-like domain HI0933_like PF03486.9 KND86853.1 - 0.089 11.2 1.1 0.18 10.2 0.8 1.5 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KND86853.1 - 0.094 12.3 0.8 0.22 11.1 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KND86853.1 - 0.11 12.2 0.4 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cyclase PF04199.8 KND86854.1 - 6.1e-15 55.3 0.0 9.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase CoA_transf_3 PF02515.12 KND86855.1 - 4.8e-34 117.2 0.0 7.5e-32 110.1 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Dioxygenase_C PF00775.16 KND86856.1 - 7.3e-46 155.7 0.0 9.4e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KND86856.1 - 1.7e-13 50.3 0.1 3.4e-13 49.3 0.0 1.5 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KND86856.1 - 5.9e-05 23.0 0.1 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 KND86856.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Cna_B PF05738.8 KND86856.1 - 0.089 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Cna protein B-type domain DUF4440 PF14534.1 KND86857.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Abhydrolase_6 PF12697.2 KND86858.1 - 7e-31 107.8 0.1 8.1e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND86858.1 - 2.6e-22 79.1 0.2 5.1e-22 78.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND86858.1 - 1.8e-09 37.5 0.0 3.4e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KND86858.1 - 2.3e-07 30.5 0.0 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KND86858.1 - 5e-05 22.8 0.0 0.052 12.9 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF1057 PF06342.7 KND86858.1 - 0.00011 21.1 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.8 KND86858.1 - 0.00012 20.4 0.1 0.023 13.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 KND86858.1 - 0.00013 21.6 0.2 0.0028 17.2 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 KND86858.1 - 0.00033 20.0 0.0 1.1 8.4 0.0 3.8 2 2 1 3 3 3 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 KND86858.1 - 0.00051 19.0 0.2 0.0029 16.5 0.1 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.8 KND86858.1 - 0.00079 19.0 0.1 0.078 12.5 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase Peptidase_S9 PF00326.16 KND86858.1 - 0.0023 17.1 0.0 0.76 8.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 KND86858.1 - 0.0023 18.1 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 KND86858.1 - 0.014 14.1 0.3 0.04 12.7 0.2 1.6 1 1 0 1 1 1 0 Chlorophyllase Esterase_phd PF10503.4 KND86858.1 - 0.021 14.0 0.2 0.032 13.4 0.2 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 KND86858.1 - 0.024 14.1 0.1 0.036 13.6 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KND86858.1 - 0.046 13.3 0.8 0.1 12.2 0.5 1.6 1 1 0 1 1 1 0 Lipase (class 3) Yip1 PF04893.12 KND86859.1 - 4.8e-12 45.7 13.4 7.9e-12 45.0 9.3 1.4 1 0 0 1 1 1 1 Yip1 domain 7TM_transglut PF14402.1 KND86859.1 - 0.38 9.6 7.0 0.55 9.1 4.9 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF1282 PF06930.7 KND86859.1 - 0.83 9.2 11.7 1.6 8.3 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Amidohydro_2 PF04909.9 KND86860.1 - 2.1e-39 135.7 0.3 2.7e-39 135.3 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase RNA_pol_I_TF PF04090.7 KND86861.1 - 0.011 15.0 0.0 0.082 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor TPR_6 PF13174.1 KND86861.1 - 0.1 13.1 4.5 19 6.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat EPSP_synthase PF00275.15 KND86861.1 - 0.13 10.6 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) WD40 PF00400.27 KND86862.1 - 3.3e-14 52.1 23.5 2.9e-06 26.9 0.6 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat ABC2_membrane PF01061.19 KND86863.1 - 1.7e-49 167.8 27.3 1.2e-27 96.5 5.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KND86863.1 - 1.3e-47 161.5 0.0 7.1e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND86863.1 - 4e-19 69.6 2.3 0.00029 20.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KND86863.1 - 7.1e-09 35.2 0.5 0.0012 18.0 0.1 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KND86863.1 - 4.1e-08 33.4 0.8 0.0007 19.6 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 KND86863.1 - 4.8e-08 32.4 0.0 0.2 10.6 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 KND86863.1 - 7.4e-08 31.7 0.6 0.008 15.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND86863.1 - 1.5e-07 31.6 0.2 0.039 14.0 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KND86863.1 - 1.7e-07 30.8 0.2 0.0051 16.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KND86863.1 - 2.4e-07 30.1 2.5 0.0032 16.9 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 KND86863.1 - 2.9e-07 30.3 0.0 0.0076 15.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 KND86863.1 - 4.4e-07 30.4 1.5 0.0068 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KND86863.1 - 4.1e-06 26.8 0.1 0.014 15.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KND86863.1 - 6.9e-06 25.7 0.6 0.0078 15.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KND86863.1 - 2.2e-05 24.2 0.1 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase SbcCD_C PF13558.1 KND86863.1 - 2.7e-05 23.9 2.0 0.19 11.6 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KND86863.1 - 4.1e-05 24.3 0.0 0.1 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KND86863.1 - 9e-05 22.1 0.5 0.19 11.3 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KND86863.1 - 9.2e-05 22.0 1.6 0.013 15.0 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KND86863.1 - 9.4e-05 21.9 2.2 0.052 12.9 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_30 PF13604.1 KND86863.1 - 0.00013 21.6 0.1 0.12 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND86863.1 - 0.00017 21.4 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KND86863.1 - 0.00037 20.6 0.2 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 KND86863.1 - 0.00037 19.4 0.7 0.1 11.5 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 KND86863.1 - 0.00037 19.9 2.8 0.22 10.9 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KND86863.1 - 0.00066 19.4 0.6 0.3 10.7 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KND86863.1 - 0.0013 19.2 0.2 0.89 10.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein PDR_CDR PF06422.7 KND86863.1 - 0.0014 18.2 0.1 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 CDR ABC transporter NTPase_1 PF03266.10 KND86863.1 - 0.0017 18.0 1.1 0.14 11.8 0.1 3.4 4 0 0 4 4 4 1 NTPase AAA_18 PF13238.1 KND86863.1 - 0.0025 18.1 0.5 0.98 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND86863.1 - 0.0034 17.1 0.8 5 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 KND86863.1 - 0.0041 16.6 0.6 0.55 9.7 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KND86863.1 - 0.0051 16.4 1.6 1.7 8.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 KND86863.1 - 0.0079 14.8 0.4 0.46 9.0 0.1 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class MMR_HSR1 PF01926.18 KND86863.1 - 0.0099 15.8 1.8 0.66 9.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF4388 PF14332.1 KND86863.1 - 0.012 15.4 0.0 0.51 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) AAA_14 PF13173.1 KND86863.1 - 0.012 15.5 0.2 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 KND86863.1 - 0.027 14.0 0.2 0.84 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.7 KND86863.1 - 0.05 12.8 1.8 0.83 8.9 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.13 KND86863.1 - 0.067 12.1 0.4 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Septin IstB_IS21 PF01695.12 KND86863.1 - 0.095 12.1 2.3 9.8 5.5 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein SRPRB PF09439.5 KND86863.1 - 0.13 11.5 0.7 15 4.7 0.1 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KND86863.1 - 0.13 12.4 0.7 25 5.0 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KND86863.1 - 0.14 11.2 0.5 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 KND86863.1 - 0.14 11.5 1.1 5.4 6.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 KND86863.1 - 0.15 11.5 1.1 8.8 5.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 KND86863.1 - 0.18 10.7 0.2 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KND86863.1 - 0.22 10.7 0.5 20 4.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein GATase PF00117.23 KND86864.1 - 1.4e-36 125.7 0.0 3.1e-36 124.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KND86864.1 - 1.5e-31 107.9 0.2 3.8e-31 106.6 0.2 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KND86864.1 - 1e-10 40.9 0.1 1.6e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KND86864.1 - 2.3e-09 37.0 0.0 8.2e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 Peptidase C26 tRNA_Me_trans PF03054.11 KND86864.1 - 0.00019 20.1 0.0 0.00034 19.2 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 KND86864.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 KND86864.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KND86864.1 - 0.011 15.0 0.0 0.04 13.2 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 KND86864.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KND86864.1 - 0.036 13.0 0.1 0.055 12.5 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 KND86864.1 - 0.041 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family MCM PF00493.18 KND86866.1 - 1.8e-129 431.2 0.3 2.5e-129 430.8 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KND86866.1 - 6.5e-19 68.5 0.1 3.6e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND86866.1 - 2.2e-07 30.2 0.0 2.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KND86866.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KND86866.1 - 0.0075 15.7 0.0 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain IceA2 PF05862.6 KND86866.1 - 0.062 13.0 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein PfkB PF00294.19 KND86867.1 - 1.3e-15 57.3 0.0 4.5e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF3085 PF11284.3 KND86867.1 - 0.043 14.0 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) CAP_N PF01213.14 KND86868.1 - 7.2e-85 285.0 0.0 1.1e-84 284.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KND86868.1 - 5.1e-54 181.9 0.9 6.5e-54 181.5 0.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KND86868.1 - 0.27 10.6 1.2 0.61 9.5 0.8 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor C Carn_acyltransf PF00755.15 KND86869.1 - 2e-173 577.6 0.0 2.3e-173 577.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Aminotran_5 PF00266.14 KND86870.1 - 2.5e-29 102.1 0.0 1.4e-18 66.7 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class-V DUF3435 PF11917.3 KND86871.1 - 0.0048 15.6 0.2 0.43 9.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3435) LPP PF04728.8 KND86872.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper 2_5_RNA_ligase2 PF13563.1 KND86873.1 - 2.3e-30 105.3 3.2 3.3e-30 104.8 1.3 2.0 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Exo_endo_phos PF03372.18 KND86873.1 - 4.7e-14 52.9 0.0 5.1e-13 49.5 0.0 2.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PAP_central PF04928.12 KND86873.1 - 4.3e-13 48.6 0.0 7.7e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 KND86873.1 - 8.6e-10 38.6 0.1 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 KND86873.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KND86873.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain MutL_C PF08676.6 KND86874.1 - 6e-22 77.7 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KND86874.1 - 2.4e-18 65.7 0.0 7e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KND86874.1 - 3.1e-12 46.3 0.0 6.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KND86874.1 - 1.6e-10 40.6 0.0 3.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PBP1_TM PF14812.1 KND86874.1 - 0.097 12.9 2.1 0.28 11.5 1.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pyr_redox_2 PF07992.9 KND86876.1 - 1.6e-06 28.1 0.0 7.6e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND86876.1 - 0.00019 21.5 0.0 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND86876.1 - 0.097 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KND86876.1 - 0.19 10.1 0.0 0.37 9.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein ETF PF01012.16 KND86877.1 - 1e-40 139.1 1.5 1.1e-40 139.0 0.3 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KND86877.1 - 2.5e-36 123.1 0.3 2.5e-36 123.1 0.2 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Cys_Met_Meta_PP PF01053.15 KND86878.1 - 1.2e-136 455.0 0.0 1.4e-136 454.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KND86878.1 - 3.4e-06 26.0 0.0 8e-06 24.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KND86878.1 - 3.9e-06 26.0 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KND86878.1 - 4.2e-05 22.7 0.0 7.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 KND86878.1 - 0.00011 21.1 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KND86878.1 - 0.00018 20.7 0.1 0.00051 19.2 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KND86878.1 - 0.0003 19.2 0.0 0.0009 17.6 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase POTRA_2 PF08479.6 KND86878.1 - 0.081 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 POTRA domain, ShlB-type DEDD_Tnp_IS110 PF01548.12 KND86878.1 - 0.092 12.4 0.0 58 3.3 0.0 3.2 3 0 0 3 3 3 0 Transposase Serinc PF03348.10 KND86879.1 - 4.8e-166 552.7 3.9 5.9e-166 552.4 2.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 KND86880.1 - 1.5e-18 66.6 35.2 4.9e-13 48.5 14.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KND86880.1 - 6e-16 58.4 0.6 6e-16 58.4 0.4 2.1 2 0 0 2 2 2 1 Nodulin-like MFS_3 PF05977.8 KND86880.1 - 0.11 10.6 5.0 0.027 12.5 0.5 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector PGAP1 PF07819.8 KND86881.1 - 6.6e-88 294.0 0.4 1.9e-87 292.5 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KND86881.1 - 6.6e-06 26.1 0.6 1.6e-05 24.9 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND86881.1 - 2.6e-05 23.9 0.0 6.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3464 PF11947.3 KND86881.1 - 0.01 15.3 0.8 0.08 12.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3464) Spt20 PF12090.3 KND86881.1 - 0.021 14.2 0.1 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 KND86881.1 - 0.038 13.7 2.7 0.072 12.8 1.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shisa PF13908.1 KND86881.1 - 0.042 14.0 1.1 0.1 12.7 0.8 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF676 PF05057.9 KND86881.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pex14_N PF04695.8 KND86881.1 - 0.21 11.6 10.0 0.22 11.5 3.9 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CFEM PF05730.6 KND86882.1 - 2.3e-07 30.5 7.4 3.9e-07 29.8 5.1 1.4 1 0 0 1 1 1 1 CFEM domain ketoacyl-synt PF00109.21 KND86883.1 - 3.7e-68 229.7 0.1 8.7e-68 228.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND86883.1 - 4e-63 213.6 0.0 6e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KND86883.1 - 1.1e-58 198.7 4.2 1.8e-58 198.0 2.9 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KND86883.1 - 1.1e-42 145.6 0.9 9.5e-25 87.3 0.5 2.6 2 0 0 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.17 KND86883.1 - 1.1e-34 118.8 0.1 3e-34 117.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KND86883.1 - 7.4e-31 107.3 1.0 2.7e-17 63.1 0.6 2.8 2 0 0 2 2 2 2 short chain dehydrogenase ADH_zinc_N PF00107.21 KND86883.1 - 5.1e-17 61.6 0.0 1.5e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KND86883.1 - 1.6e-16 60.5 0.0 1.4e-15 57.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KND86883.1 - 1.6e-10 41.9 0.0 5.5e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KND86883.1 - 4.3e-09 36.2 0.0 1.3e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KND86883.1 - 8.5e-09 35.5 0.1 4.8e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KND86883.1 - 3.4e-07 30.8 0.0 7.7e-06 26.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KND86883.1 - 5.2e-07 29.4 0.1 1.3e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KND86883.1 - 1.3e-06 28.7 0.0 3.5e-05 24.1 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86883.1 - 3e-06 26.8 0.0 3.9e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KND86883.1 - 7.3e-06 25.5 0.4 0.18 11.2 0.0 3.1 3 1 0 3 3 3 2 Putative methyltransferase Thiolase_N PF00108.18 KND86883.1 - 0.016 14.2 0.2 0.029 13.3 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KND86883.1 - 0.28 10.2 0.0 0.57 9.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.23 KND86884.1 - 7.8e-68 228.7 0.0 1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND86884.1 - 1.6e-11 44.9 0.0 3.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2_2 PF12756.2 KND86885.1 - 4.6e-23 81.2 4.7 3.7e-22 78.3 1.2 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KND86885.1 - 0.0053 16.8 1.1 0.37 11.0 0.0 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND86885.1 - 0.18 12.0 1.2 0.69 10.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KND86885.1 - 0.39 11.1 7.2 20 5.7 0.0 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3328 PF11807.3 KND86886.1 - 4e-32 111.6 2.1 7.3e-28 97.7 0.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) DUF2427 PF10348.4 KND86887.1 - 0.00024 20.6 1.6 0.00058 19.4 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) SUR7 PF06687.7 KND86887.1 - 0.034 13.7 1.8 0.063 12.8 1.3 1.4 1 0 0 1 1 1 0 SUR7/PalI family DOMON PF03351.12 KND86887.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 DOMON domain DIOX_N PF14226.1 KND86888.1 - 6.4e-22 78.2 0.0 9.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND86888.1 - 5e-14 52.3 0.0 9.1e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OPT PF03169.10 KND86889.1 - 2.6e-06 26.2 0.1 2.8e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CFEM PF05730.6 KND86890.1 - 2.2e-10 40.1 8.8 3.8e-10 39.4 6.1 1.4 1 0 0 1 1 1 1 CFEM domain Herpes_capsid PF06112.6 KND86890.1 - 1.4 8.9 8.2 1.9 8.4 5.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MFS_1 PF07690.11 KND86891.1 - 1.8e-09 36.8 65.9 2.5e-07 29.7 29.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KND86891.1 - 5.7e-05 21.5 24.1 8.4e-05 20.9 16.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BC10 PF06726.7 KND86891.1 - 0.05 13.6 1.2 12 5.9 0.1 3.0 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Pyr_redox_2 PF07992.9 KND86892.1 - 7e-19 68.5 3.0 4.5e-06 26.6 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND86892.1 - 5e-11 42.8 0.5 6.3e-09 36.1 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND86892.1 - 2.6e-07 29.8 0.9 0.0057 15.5 0.0 3.4 4 0 0 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KND86892.1 - 5.7e-06 25.2 0.4 0.095 11.3 0.2 3.0 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KND86892.1 - 1.4e-05 24.9 1.0 4.3 7.1 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KND86892.1 - 2.2e-05 23.5 0.7 0.37 9.6 0.2 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KND86892.1 - 7.1e-05 22.9 1.8 0.079 13.0 0.0 3.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND86892.1 - 0.00019 20.4 0.1 0.0043 16.0 0.1 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KND86892.1 - 0.0068 15.5 0.9 0.11 11.4 0.5 2.3 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KND86892.1 - 0.039 12.8 0.3 1.5 7.5 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 KND86892.1 - 0.048 13.6 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain Amino_oxidase PF01593.19 KND86892.1 - 0.056 12.5 0.2 0.71 8.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF1188 PF06690.6 KND86892.1 - 0.098 11.7 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) HI0933_like PF03486.9 KND86892.1 - 0.13 10.7 2.0 0.99 7.7 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 KND86892.1 - 4.8 5.9 7.5 8.2 5.1 2.7 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A ketoacyl-synt PF00109.21 KND86893.1 - 1e-67 228.2 0.0 2.9e-67 226.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KND86893.1 - 7.2e-59 198.4 0.5 1.6e-58 197.3 0.3 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KND86893.1 - 1e-57 195.5 0.0 1.7e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KND86893.1 - 5.6e-53 180.3 0.0 4.2e-40 138.0 0.1 2.5 2 0 0 2 2 2 2 Acyl transferase domain adh_short PF00106.20 KND86893.1 - 1.3e-43 148.8 0.1 1.3e-43 148.8 0.1 2.0 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND86893.1 - 4.3e-34 116.8 0.2 2.4e-33 114.4 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KND86893.1 - 2.1e-18 66.1 0.0 6.7e-18 64.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KND86893.1 - 1.7e-16 60.4 0.0 4.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KND86893.1 - 7.9e-16 59.1 0.0 3.6e-15 56.9 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND86893.1 - 1.8e-09 37.3 0.3 1.3e-08 34.5 0.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 KND86893.1 - 1.9e-09 37.4 0.0 6.3e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KND86893.1 - 2.6e-07 30.8 0.2 8.4e-07 29.1 0.1 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KND86893.1 - 1.5e-06 27.8 0.0 4.5e-06 26.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86893.1 - 4.5e-06 27.2 0.0 1.7e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND86893.1 - 3.8e-05 24.0 0.0 0.00012 22.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KND86893.1 - 0.00077 18.9 0.0 0.046 13.1 0.0 3.1 3 0 0 3 3 3 1 Putative methyltransferase Ubie_methyltran PF01209.13 KND86893.1 - 0.025 13.7 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KND86893.1 - 0.099 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 KND86893.1 - 0.19 10.5 0.0 0.33 9.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase bZIP_1 PF00170.16 KND86894.1 - 5.1e-06 26.3 6.5 1.3e-05 25.0 4.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND86894.1 - 0.014 15.1 12.4 0.022 14.5 8.0 1.7 2 0 0 2 2 2 0 Basic region leucine zipper RILP PF11461.3 KND86894.1 - 0.024 14.7 0.1 0.072 13.2 0.1 1.8 1 0 0 1 1 1 0 Rab interacting lysosomal protein bZIP_Maf PF03131.12 KND86894.1 - 0.095 13.0 7.8 0.22 11.8 5.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor SRP-alpha_N PF04086.8 KND86894.1 - 0.25 10.7 8.3 0.39 10.0 5.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PI3K_1B_p101 PF10486.4 KND86894.1 - 0.91 7.0 6.2 1.5 6.3 4.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.4 KND86894.1 - 1.8 6.7 14.0 2.7 6.1 9.7 1.2 1 0 0 1 1 1 0 Transmembrane protein MDFI PF15316.1 KND86894.1 - 2.7 7.9 8.4 6.1 6.8 5.8 1.7 1 0 0 1 1 1 0 MyoD family inhibitor PPP4R2 PF09184.6 KND86894.1 - 2.9 7.3 9.0 4.5 6.7 6.2 1.3 1 0 0 1 1 1 0 PPP4R2 p450 PF00067.17 KND86895.1 - 1.6e-58 198.3 0.0 2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 4HBT_2 PF13279.1 KND86896.1 - 1.7e-06 28.5 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ABC_tran PF00005.22 KND86897.1 - 2.1e-38 131.7 0.0 8.6e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND86897.1 - 1.7e-27 96.5 35.7 1.8e-18 66.9 10.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KND86897.1 - 3.8e-08 32.8 0.1 0.017 14.3 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KND86897.1 - 9.9e-06 25.6 0.2 0.0024 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KND86897.1 - 1.3e-05 25.3 0.0 0.064 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KND86897.1 - 0.0003 20.5 0.0 0.0021 17.8 0.0 2.3 3 0 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 KND86897.1 - 0.00037 20.6 0.1 0.33 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KND86897.1 - 0.00065 19.2 0.3 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 KND86897.1 - 0.002 17.9 1.3 2.3 8.1 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KND86897.1 - 0.0074 16.6 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KND86897.1 - 0.0086 15.5 0.0 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KND86897.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KND86897.1 - 0.075 12.9 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KND86897.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KND86897.1 - 0.19 10.4 0.1 0.39 9.3 0.1 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 KND86897.1 - 0.21 10.7 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Methyltransf_2 PF00891.13 KND86898.1 - 5e-22 78.2 0.0 7.8e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Sugar_tr PF00083.19 KND86899.1 - 2.4e-32 112.1 28.0 1.8e-27 96.0 5.7 2.4 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 KND86899.1 - 1.9e-23 82.7 32.8 2.4e-16 59.4 13.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 KND86899.1 - 0.011 15.5 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 MFS_1 like family Mucin PF01456.12 KND86899.1 - 0.41 10.4 0.1 0.41 10.4 0.0 2.1 3 0 0 3 3 3 0 Mucin-like glycoprotein ABC1 PF03109.11 KND86900.1 - 8.3e-25 87.0 0.0 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KND86900.1 - 0.0021 17.8 0.3 0.019 14.6 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family p450 PF00067.17 KND86901.1 - 1.1e-54 185.7 0.0 1.4e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 KND86903.1 - 5.6e-13 49.1 0.0 1.8e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND86903.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KND86903.1 - 0.079 12.1 0.0 0.39 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain BNR_2 PF13088.1 KND86905.1 - 1.1e-16 60.9 1.1 3.2e-12 46.3 0.1 2.6 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KND86905.1 - 7e-05 22.0 22.2 0.56 10.2 0.3 6.5 5 0 0 5 5 5 4 BNR/Asp-box repeat Glyco_transf_90 PF05686.7 KND86906.1 - 2.9e-09 36.0 0.1 9.2e-05 21.2 0.0 3.5 3 1 0 3 3 3 3 Glycosyl transferase family 90 AMP-binding PF00501.23 KND86907.1 - 0 2414.3 14.3 9.5e-84 281.1 0.1 10.3 10 0 0 10 10 10 10 AMP-binding enzyme Condensation PF00668.15 KND86907.1 - 0 1416.3 0.0 2.3e-51 174.4 0.0 10.4 10 0 0 10 10 10 10 Condensation domain PP-binding PF00550.20 KND86907.1 - 1e-119 390.8 24.9 1.1e-12 48.0 0.1 12.3 12 0 0 12 12 12 11 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 KND86907.1 - 8e-41 139.5 0.1 1.9e-40 138.3 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KND86907.1 - 7.1e-05 22.3 0.0 0.00021 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AATase PF07247.7 KND86907.1 - 0.00012 20.7 0.0 1.5 7.3 0.0 4.7 5 0 0 5 5 5 1 Alcohol acetyltransferase 3Beta_HSD PF01073.14 KND86907.1 - 0.012 14.2 2.4 0.79 8.3 0.0 2.7 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Tox-REase-5 PF15648.1 KND86907.1 - 0.097 12.9 0.3 42 4.5 0.0 4.4 5 0 0 5 5 4 0 Restriction endonuclease fold toxin 5 Csm1 PF12539.3 KND86907.1 - 0.15 12.5 4.0 36 4.9 0.0 5.5 7 0 0 7 7 7 0 Chromosome segregation protein Csm1/Pcs1 DUF4454 PF14628.1 KND86907.1 - 1.4 8.4 0.0 3.2 7.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) IKI3 PF04762.7 KND86907.1 - 2.4 5.8 0.0 4.1 5.0 0.0 1.3 1 0 0 1 1 1 0 IKI3 family MS_channel PF00924.13 KND86907.1 - 2.6 7.3 0.0 5.4 6.2 0.0 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel ISG65-75 PF11727.3 KND86907.1 - 5.8 5.8 0.1 10 5.0 0.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Thioesterase PF00975.15 KND86908.1 - 2.8e-10 40.8 0.0 5.5e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KND86908.1 - 8.4e-07 29.1 0.1 1.1e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND86908.1 - 0.033 13.9 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_2c PF01411.14 KND86910.1 - 2e-13 49.5 0.0 2.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KND86910.1 - 4.4e-05 23.2 0.5 8.2e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Lactamase_B_2 PF12706.2 KND86911.1 - 4.2e-36 124.3 0.1 6.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KND86911.1 - 2.5e-09 37.0 0.1 6.9e-09 35.6 0.0 1.9 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KND86911.1 - 0.00022 20.9 0.1 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Aminotran_4 PF01063.14 KND86912.1 - 5.1e-20 71.9 0.0 6e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV bZIP_1 PF00170.16 KND86913.1 - 1.2e-05 25.1 5.4 3.5e-05 23.6 3.8 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND86913.1 - 0.086 12.6 9.2 0.19 11.6 6.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper TB2_DP1_HVA22 PF03134.14 KND86914.1 - 2.8e-30 103.9 7.0 4e-30 103.4 4.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.7 KND86915.1 - 4.9e-86 286.3 0.0 6.3e-86 286.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Dynamin_N PF00350.18 KND86916.1 - 1.2e-18 67.5 0.6 4.3e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KND86916.1 - 3e-10 40.0 0.1 1.3e-09 38.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND86916.1 - 3e-08 33.3 0.8 2.4e-07 30.3 0.6 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.21 KND86916.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Miro PF08477.8 KND86916.1 - 0.024 15.1 0.1 0.35 11.3 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KND86916.1 - 0.025 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KND86916.1 - 0.025 14.8 0.0 0.08 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PMEI PF04043.10 KND86916.1 - 0.027 14.3 0.1 0.027 14.3 0.1 2.7 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor AAA_17 PF13207.1 KND86916.1 - 0.09 13.5 0.1 2 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF883 PF05957.8 KND86916.1 - 0.71 10.2 10.4 0.74 10.2 0.3 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) WSC PF01822.14 KND86918.1 - 3.9e-10 39.5 4.1 3.9e-10 39.5 2.8 2.7 2 1 0 2 2 2 1 WSC domain Meth_synt_2 PF01717.13 KND86919.1 - 5.3e-21 74.9 0.0 1.7e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KND86919.1 - 1.5e-07 31.0 0.0 0.00053 19.3 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain DUF2360 PF10152.4 KND86920.1 - 3.4 7.9 12.2 12 6.1 0.2 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Methyltransf_23 PF13489.1 KND86921.1 - 8.9e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND86921.1 - 1.1e-07 32.1 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND86921.1 - 2.4e-07 30.4 0.0 3.4e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86921.1 - 4.9e-06 27.1 0.0 9.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND86921.1 - 1.6e-05 25.3 0.0 0.00015 22.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND86921.1 - 0.00039 20.7 0.0 0.00098 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND86921.1 - 0.007 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KND86921.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KND86921.1 - 0.027 14.4 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC2_membrane PF01061.19 KND86922.1 - 1.7e-77 259.3 58.0 1e-41 142.3 14.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KND86922.1 - 8.9e-35 119.9 0.0 6.1e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KND86922.1 - 3.9e-29 100.3 0.1 6.7e-25 86.7 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KND86922.1 - 2.6e-09 37.0 0.1 9.5e-09 35.2 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KND86922.1 - 2.1e-07 30.8 0.1 0.0052 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND86922.1 - 2.1e-06 27.2 0.2 0.005 16.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 KND86922.1 - 2.5e-05 24.3 0.0 0.08 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KND86922.1 - 2.6e-05 23.7 1.7 0.0038 16.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KND86922.1 - 2.6e-05 24.3 0.0 0.11 12.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KND86922.1 - 5.6e-05 22.5 0.2 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 KND86922.1 - 0.00017 21.2 0.8 0.52 9.9 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 KND86922.1 - 0.00017 21.6 0.1 0.043 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KND86922.1 - 0.00017 22.3 0.0 0.032 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KND86922.1 - 0.00028 20.0 41.1 0.0012 17.9 7.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 KND86922.1 - 0.00031 19.9 0.0 0.0031 16.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KND86922.1 - 0.0015 18.5 0.1 0.059 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND86922.1 - 0.0028 17.9 0.0 0.24 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KND86922.1 - 0.0031 17.1 1.5 1.3 8.6 0.1 2.4 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 KND86922.1 - 0.012 14.8 0.0 0.93 8.6 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 KND86922.1 - 0.018 14.5 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KND86922.1 - 0.052 12.9 0.3 3.3 7.0 0.0 2.6 3 0 0 3 3 2 0 AAA-like domain AAA_19 PF13245.1 KND86922.1 - 0.057 13.1 2.6 6.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KND86922.1 - 0.068 13.6 0.0 8 6.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KND86922.1 - 0.1 12.8 0.3 18 5.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KND86922.1 - 0.13 11.8 0.4 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KND86922.1 - 0.13 11.7 0.8 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KND86922.1 - 0.67 10.2 0.0 0.67 10.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain Methyltransf_16 PF10294.4 KND86923.1 - 7.2e-28 97.2 0.0 4.7e-27 94.5 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.1 KND86923.1 - 3.2e-05 23.6 0.0 7.7e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND86923.1 - 0.0018 17.6 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KND86923.1 - 0.003 18.0 0.1 0.0087 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND86923.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86923.1 - 0.039 13.9 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KND86924.1 - 2.1e-15 56.7 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND86924.1 - 9.5e-08 32.6 0.0 8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND86924.1 - 3.9e-07 30.4 0.0 0.00045 20.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KND86924.1 - 1.6e-06 28.5 0.0 0.00099 19.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KND86924.1 - 1.5e-05 24.6 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KND86924.1 - 0.00012 22.3 0.0 0.00077 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND86924.1 - 0.00059 19.8 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND86924.1 - 0.0009 18.6 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KND86924.1 - 0.024 13.6 0.0 0.093 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 KND86924.1 - 0.077 12.0 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KND86924.1 - 0.12 11.3 0.0 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KND86924.1 - 0.13 11.3 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NADH_dh_m_C1 PF15088.1 KND86925.1 - 0.086 12.3 0.4 0.31 10.5 0.3 2.0 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial AMP-binding PF00501.23 KND86927.1 - 1.8e-69 234.1 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KND86927.1 - 1.9e-07 30.2 0.3 3.4e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 KND86927.1 - 0.0015 19.4 0.1 0.012 16.5 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 KND86927.1 - 0.1 12.8 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Phosphopantetheine attachment site p450 PF00067.17 KND86928.1 - 1.6e-59 201.6 0.1 5.7e-31 107.5 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Arylsulfotran_2 PF14269.1 KND86929.1 - 2.9e-48 164.5 1.6 3.8e-48 164.1 1.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KND86929.1 - 6.9e-21 74.2 0.1 1.2e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) RuBisCO_small PF00101.15 KND86929.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain P12 PF12669.2 KND86930.1 - 5.8 7.1 10.6 9.6 6.4 7.3 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Pex24p PF06398.6 KND86931.1 - 2.8e-96 322.4 0.2 3.7e-96 322.0 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin TPR_1 PF00515.23 KND86933.1 - 2.2e-19 68.1 0.1 1.2e-05 24.6 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND86933.1 - 5.4e-18 63.3 1.4 0.0017 18.1 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KND86933.1 - 6e-18 64.2 1.2 1.6e-11 43.6 0.1 4.2 1 1 2 4 4 4 2 TPR repeat TPR_14 PF13428.1 KND86933.1 - 5e-13 48.4 3.0 0.28 11.9 0.0 5.7 4 1 2 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND86933.1 - 5.4e-12 45.4 5.5 5e-07 29.5 0.4 4.1 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KND86933.1 - 6.7e-11 41.1 0.0 0.00043 19.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND86933.1 - 2.8e-10 39.2 5.5 0.0045 16.6 0.1 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND86933.1 - 9.7e-09 35.6 5.3 3.5e-06 27.5 0.2 4.2 2 2 1 4 4 4 1 Tetratricopeptide repeat APC8 PF04049.8 KND86933.1 - 9.2e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_17 PF13431.1 KND86933.1 - 4.2e-05 23.4 0.0 0.37 11.1 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND86933.1 - 0.00096 19.4 1.2 1.4 9.3 0.0 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KND86933.1 - 0.02 14.7 2.6 0.59 10.0 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND86933.1 - 0.16 12.4 8.9 76 4.0 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND86933.1 - 0.28 11.1 5.8 0.59 10.1 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 KND86934.1 - 5.6e-08 32.9 0.1 8e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KND86934.1 - 2.9e-06 26.5 0.4 3.1e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KND86934.1 - 3.9e-06 27.6 0.0 1.3e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND86934.1 - 1.3e-05 24.8 3.0 0.00014 21.5 2.0 2.3 1 1 0 1 1 1 1 Part of AAA domain PRK PF00485.13 KND86934.1 - 8.5e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 KND86934.1 - 9.5e-05 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND86934.1 - 0.00013 22.2 0.3 0.0008 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND86934.1 - 0.00024 20.9 1.2 0.0032 17.3 0.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KND86934.1 - 0.00027 20.5 0.2 0.00068 19.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KND86934.1 - 0.00093 19.3 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KND86934.1 - 0.0036 16.2 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.14 KND86934.1 - 0.0037 16.7 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KND86934.1 - 0.0051 16.5 0.1 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 NTPase NACHT PF05729.7 KND86934.1 - 0.0058 16.3 0.0 0.014 15.0 0.0 1.6 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 KND86934.1 - 0.0073 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KND86934.1 - 0.0084 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein KTI12 PF08433.5 KND86934.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 KND86934.1 - 0.019 14.6 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KND86934.1 - 0.026 14.5 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KND86934.1 - 0.028 13.8 0.1 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KND86934.1 - 0.032 13.8 0.0 0.034 13.7 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KND86934.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND86934.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.17 KND86934.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 KND86934.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 KND86934.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.7 KND86934.1 - 0.11 11.4 0.3 0.27 10.2 0.0 1.8 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KND86934.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KND86935.1 - 1.1e-10 41.8 0.0 2.2e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 KND86936.1 - 4.4e-16 58.8 0.0 1.4e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND86936.1 - 6.8e-13 48.2 0.0 2.6e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KND86936.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND86936.1 - 0.017 14.8 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND86936.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF768 PF05589.6 KND86939.1 - 0.02 14.8 0.1 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Adeno_E1B_55K_N PF04623.7 KND86939.1 - 0.16 12.4 3.7 2.6 8.6 1.5 3.0 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus DUF4540 PF15073.1 KND86939.1 - 0.22 12.0 2.3 0.41 11.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4540) DAHP_synth_1 PF00793.15 KND86941.1 - 2.1e-97 325.0 0.0 2.4e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.4 KND86943.1 - 1.5e-14 53.9 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Arm PF00514.18 KND86945.1 - 0.68 9.8 6.8 5.3 7.0 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pam16 PF03656.8 KND86946.1 - 1.2e-30 105.8 0.1 1.5e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Pam16 COX14 PF14880.1 KND86947.1 - 7.5e-18 63.9 0.4 7.5e-18 63.9 0.3 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly VirionAssem_T7 PF11653.3 KND86947.1 - 0.024 15.3 4.2 1.7 9.4 1.3 2.6 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein PRP4 PF08799.6 KND86947.1 - 0.029 13.6 0.3 0.079 12.2 0.2 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Cas_Cas02710 PF09670.5 KND86947.1 - 0.036 12.6 0.2 0.048 12.3 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Ribosomal_L13e PF01294.13 KND86948.1 - 1.8e-65 219.7 4.2 2.2e-65 219.4 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e BPL_N PF09825.4 KND86949.1 - 2.9e-134 447.5 0.0 3.5e-134 447.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KND86949.1 - 1.6e-17 63.7 0.0 2.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.8 KND86950.1 - 0.0013 18.5 8.6 0.0022 17.8 6.0 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KND86950.1 - 0.012 15.5 2.7 0.017 15.1 1.8 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KND86950.1 - 0.031 14.0 5.3 0.11 12.3 3.7 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Toxin_25 PF08095.6 KND86950.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.0 2 1 0 2 2 2 0 Hefutoxin family p450 PF00067.17 KND86951.1 - 1e-53 182.5 0.0 1.2e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DPM3 PF08285.6 KND86952.1 - 7.5e-33 112.2 0.1 8.3e-33 112.1 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Cytochrom_B_N PF00033.14 KND86952.1 - 0.0078 15.5 0.1 0.0085 15.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Oxidored-like PF09791.4 KND86954.1 - 1.2e-25 88.6 3.3 1.2e-25 88.6 2.3 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Fungal_trans PF04082.13 KND86955.1 - 1e-22 80.2 0.0 1.6e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86955.1 - 3.3e-06 26.9 12.8 5.4e-06 26.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KND86955.1 - 0.0025 17.7 4.2 0.0049 16.7 2.9 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain Clusterin PF01093.12 KND86955.1 - 0.38 9.4 0.3 0.6 8.8 0.2 1.2 1 0 0 1 1 1 0 Clusterin DPM3 PF08285.6 KND86957.1 - 7.5e-33 112.2 0.1 8.3e-33 112.1 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Cytochrom_B_N PF00033.14 KND86957.1 - 0.0078 15.5 0.1 0.0085 15.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Pribosyltran PF00156.22 KND86960.1 - 2.1e-09 37.1 0.2 1e-08 34.9 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Tfb2 PF03849.9 KND86961.1 - 2.3e-131 437.8 0.0 2.8e-131 437.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KND86961.1 - 0.00047 19.9 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NRDE PF05742.7 KND86962.1 - 1.1e-38 133.1 0.0 1.5e-37 129.3 0.0 2.0 1 1 0 1 1 1 1 NRDE protein Metal_resist PF13801.1 KND86962.1 - 0.043 13.7 1.0 0.082 12.9 0.7 1.4 1 0 0 1 1 1 0 Heavy-metal resistance 4HBT PF03061.17 KND86963.1 - 2.5e-14 53.1 0.0 3.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KND86963.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 KND86963.1 - 0.012 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Peptidase_S10 PF00450.17 KND86967.1 - 5.4e-79 266.2 0.0 7.2e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase FA_hydroxylase PF04116.8 KND86967.1 - 8e-18 64.9 14.2 2.2e-17 63.4 9.8 1.8 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Abhydrolase_5 PF12695.2 KND86967.1 - 0.0087 15.8 0.0 0.048 13.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pex14_N PF04695.8 KND86968.1 - 0.018 15.0 1.8 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M35 PF02102.10 KND86969.1 - 2.4e-21 75.7 1.9 2.5e-21 75.7 1.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KND86969.1 - 2.6e-05 24.7 0.1 2.9e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase COG4 PF08318.7 KND86971.1 - 2.7e-84 282.7 0.0 3.8e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Choline_transpo PF04515.7 KND86972.1 - 1.7e-101 339.2 22.5 1.7e-101 339.2 15.6 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter APG17 PF04108.7 KND86973.1 - 1.9e-94 316.8 1.3 2.7e-94 316.2 0.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Peptidase_C2 PF00648.16 KND86974.1 - 1e-48 165.9 0.8 5.6e-36 124.0 0.4 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease AMP-binding PF00501.23 KND86975.1 - 1.7e-77 260.6 0.1 4.4e-77 259.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KND86975.1 - 8.3e-64 214.8 0.1 2.2e-62 210.2 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KND86975.1 - 4.5e-33 114.5 6.4 8.2e-31 107.1 3.9 2.9 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KND86975.1 - 2.3e-21 76.3 0.3 5.1e-12 45.7 0.0 4.1 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KND86975.1 - 7.3e-21 75.0 0.9 7.3e-21 75.0 0.6 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND86975.1 - 1.6e-17 63.7 7.2 1.9e-15 56.9 3.0 2.6 2 1 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 KND86975.1 - 1.3e-10 41.5 2.2 5.8e-07 29.6 2.0 3.6 2 1 0 2 2 2 1 NADH(P)-binding PP-binding PF00550.20 KND86975.1 - 3.7e-10 39.9 0.0 1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KND86975.1 - 1.6e-07 32.1 4.5 1.8e-07 32.0 0.2 3.2 4 0 0 4 4 3 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 KND86975.1 - 3.1e-06 26.2 0.9 0.011 14.6 0.2 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KND86975.1 - 6e-05 21.8 0.0 0.021 13.5 0.0 2.9 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KND86975.1 - 7.9e-05 21.6 1.4 0.0016 17.3 0.1 3.2 2 1 0 2 2 2 1 RmlD substrate binding domain ApbA PF02558.11 KND86975.1 - 0.0073 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DFP PF04127.10 KND86975.1 - 0.022 14.3 5.7 0.0098 15.5 1.7 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 KND86975.1 - 0.089 12.5 2.1 0.24 11.2 1.5 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KND86975.1 - 0.17 11.1 0.8 8 5.6 0.0 2.9 3 0 0 3 3 3 0 NmrA-like family AA_permease PF00324.16 KND86977.1 - 9.4e-131 436.4 52.7 1.1e-130 436.1 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND86977.1 - 2.7e-32 111.8 57.7 3.3e-32 111.5 40.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 KND86978.1 - 2.7e-19 69.0 1.3 5.5e-19 68.0 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND86978.1 - 2.6e-08 33.6 13.4 6.4e-08 32.3 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 KND86979.1 - 4.6e-114 382.2 0.1 6.2e-114 381.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase zf-C3HC4 PF00097.20 KND86980.1 - 0.0039 16.8 6.4 0.01 15.4 4.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND86980.1 - 0.047 13.4 3.4 0.11 12.2 1.8 2.2 2 1 0 2 2 2 0 RING-type zinc-finger HTH_IclR PF09339.5 KND86980.1 - 0.078 12.5 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-RING_5 PF14634.1 KND86980.1 - 0.16 11.7 14.5 0.033 13.9 6.2 2.8 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.1 KND86980.1 - 0.35 10.4 6.6 1.8 8.1 4.6 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3133 PF11331.3 KND86980.1 - 3.3 7.3 14.1 0.1 12.1 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zf-RING_2 PF13639.1 KND86980.1 - 4.5 7.1 14.9 0.57 10.0 6.4 2.6 2 1 0 2 2 2 0 Ring finger domain UPF0052 PF01933.13 KND86981.1 - 3.3e-48 164.5 0.1 2.1e-32 112.6 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 Nucleoplasmin PF03066.10 KND86981.1 - 0.0082 15.6 4.0 0.014 14.8 0.9 2.1 2 0 0 2 2 2 1 Nucleoplasmin Sigma70_ner PF04546.8 KND86981.1 - 0.16 11.5 3.3 0.13 11.8 0.6 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Bd3614_N PF14442.1 KND86981.1 - 3.1 7.7 9.9 8.1 6.4 6.9 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal ADH_zinc_N PF00107.21 KND86982.1 - 1.9e-29 101.8 0.8 3.3e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND86982.1 - 1.1e-15 58.6 0.1 5e-15 56.5 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND86982.1 - 1.5e-10 40.7 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KND86982.1 - 0.0036 17.2 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KND86982.1 - 0.087 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NicO PF03824.11 KND86983.1 - 3.1e-43 148.0 1.8 3.1e-43 148.0 1.2 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein COX4_pro_2 PF07835.7 KND86983.1 - 0.83 9.6 0.0 0.83 9.6 0.0 3.4 3 1 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV VirB3 PF05101.8 KND86983.1 - 6.4 6.8 11.3 9.5 6.2 0.2 3.5 4 0 0 4 4 4 0 Type IV secretory pathway, VirB3-like protein CFEM PF05730.6 KND86985.1 - 3.1e-29 100.5 57.9 1.1e-09 37.9 9.6 3.7 3 0 0 3 3 3 3 CFEM domain DUF3437 PF11919.3 KND86985.1 - 0.44 10.2 1.5 5.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) 4HBT PF03061.17 KND86986.1 - 6.2e-14 51.8 1.1 6.2e-14 51.8 0.8 1.9 2 1 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.1 KND86986.1 - 0.0073 16.7 0.0 0.0091 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_3 PF13622.1 KND86986.1 - 0.012 15.3 1.3 0.017 14.8 0.9 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 KND86986.1 - 0.05 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Glyoxalase_3 PF13468.1 KND86987.1 - 1e-22 80.8 0.2 2.1e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain BTB PF00651.26 KND86987.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_S7e PF01251.13 KND86991.1 - 5.1e-84 280.4 0.5 5.7e-84 280.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e WSC PF01822.14 KND86992.1 - 4.3e-08 32.9 5.0 1.1e-07 31.7 3.5 1.7 1 0 0 1 1 1 1 WSC domain Hydantoinase_B PF02538.9 KND86993.1 - 1.4e-186 620.8 0.0 1.9e-186 620.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KND86993.1 - 2.3e-90 302.6 0.7 8.5e-90 300.7 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KND86993.1 - 1.6e-52 177.5 0.1 1.2e-50 171.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 KND86994.1 - 7e-32 110.4 22.6 7e-32 110.4 15.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MLANA PF14991.1 KND86994.1 - 0.016 15.2 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein melan-A Got1 PF04178.7 KND86994.1 - 0.03 14.4 0.9 0.03 14.4 0.6 3.8 2 2 2 4 4 4 0 Got1/Sft2-like family Abhydrolase_4 PF08386.5 KND86996.1 - 5.8e-11 42.1 0.0 6.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.2 KND86996.1 - 0.00079 19.1 0.0 0.00089 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND86996.1 - 0.034 14.0 0.1 0.048 13.5 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF563 PF04577.9 KND86997.1 - 3.4e-28 98.9 0.0 6.9e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FAD_binding_4 PF01565.18 KND86997.1 - 4.2e-21 74.8 2.9 1e-20 73.6 2.0 1.7 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.22 KND86998.1 - 1.8e-71 235.9 0.9 1.7e-23 82.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 KND86999.1 - 5.7e-21 74.7 0.0 3.9e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein RIB43A PF05914.7 KND87001.1 - 0.068 11.7 0.2 0.09 11.3 0.1 1.2 1 0 0 1 1 1 0 RIB43A polyprenyl_synt PF00348.12 KND87002.1 - 0.00014 20.8 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RIO1 PF01163.17 KND87003.1 - 4.5e-69 231.6 0.3 1.1e-68 230.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KND87003.1 - 0.0003 20.6 0.1 0.22 11.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KND87003.1 - 0.021 13.8 0.0 0.28 10.2 0.0 2.2 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NmrA PF05368.8 KND87004.1 - 8.3e-05 21.9 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KND87004.1 - 0.0022 17.0 0.0 0.0028 16.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KND87004.1 - 0.022 14.8 0.3 0.11 12.5 0.2 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KND87004.1 - 1.1 9.0 3.9 9.5 6.0 2.7 2.0 1 1 0 1 1 1 0 ThiF family Asp PF00026.18 KND87005.1 - 4.5e-59 200.2 1.4 5.3e-59 200.0 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND87005.1 - 1.4e-06 28.3 0.0 7.3e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND87005.1 - 0.011 16.1 0.1 2.7 8.5 0.0 2.8 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.1 KND87005.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF924 PF06041.6 KND87006.1 - 2.4e-38 131.7 0.0 2.3e-35 122.0 0.0 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Dynactin_p62 PF05502.8 KND87008.1 - 2.4e-154 514.7 0.0 3e-154 514.3 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family LPP PF04728.8 KND87009.1 - 0.13 12.1 0.1 1.4 8.7 0.0 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ESAG1 PF03238.8 KND87010.1 - 0.074 12.3 0.0 2.5 7.3 0.0 2.0 1 1 1 2 2 2 0 ESAG protein ICL PF00463.16 KND87011.1 - 3.6e-117 391.7 0.3 4.4e-117 391.4 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KND87011.1 - 4.1e-06 26.1 0.0 8.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_1_2 PF00155.16 KND87012.1 - 1.8e-12 46.9 0.0 3.3e-12 46.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KND87012.1 - 0.035 12.6 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase GATase PF00117.23 KND87013.1 - 0.0017 17.8 0.0 0.0051 16.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Zn_clus PF00172.13 KND87014.1 - 8.5e-09 35.1 8.7 1.7e-08 34.2 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND87014.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ILVD_EDD PF00920.16 KND87015.1 - 1.5e-134 449.2 3.4 1.4e-83 281.0 1.5 2.0 1 1 1 2 2 2 2 Dehydratase family Methyltransf_23 PF13489.1 KND87017.1 - 8.4e-15 54.8 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87017.1 - 4.9e-09 36.7 0.2 1.6e-07 31.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87017.1 - 1.1e-07 32.2 0.0 1.8e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87017.1 - 1.1e-06 29.0 0.0 3.5e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87017.1 - 3.4e-05 23.4 0.0 0.00068 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KND87017.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KND87017.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 KND87017.1 - 0.029 14.7 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KND87017.1 - 0.042 12.9 0.0 2.2 7.3 0.0 2.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KND87017.1 - 0.046 12.8 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KND87017.1 - 0.048 12.7 0.0 0.098 11.6 0.0 1.4 2 0 0 2 2 2 0 Putative methyltransferase Ldh_2 PF02615.9 KND87018.1 - 9.8e-95 317.0 0.0 1.1e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase APH PF01636.18 KND87019.1 - 6.3e-09 35.9 0.1 1.9e-08 34.3 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87019.1 - 4.3e-07 29.7 0.0 8.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Asp PF00026.18 KND87021.1 - 3.3e-06 26.5 0.0 2.1e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 KND87021.1 - 0.00056 18.6 0.5 0.00087 18.0 0.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_gE PF02480.11 KND87021.1 - 0.079 11.2 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Beta-APP PF03494.8 KND87021.1 - 0.12 11.9 3.8 0.17 11.3 2.0 1.7 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) WD40 PF00400.27 KND87022.1 - 5.3e-59 194.1 24.6 3.4e-11 42.5 0.1 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KND87022.1 - 8.1e-11 40.7 3.7 0.044 11.9 0.0 4.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 F-box-like PF12937.2 KND87022.1 - 8.2e-11 41.4 0.8 2e-10 40.2 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND87022.1 - 5.1e-10 38.7 0.4 1.2e-09 37.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 KND87022.1 - 0.006 15.3 2.2 1.1 7.8 0.0 2.8 2 1 0 3 3 3 2 Nup133 N terminal like Cupin_2 PF07883.6 KND87024.1 - 1.8e-05 24.1 0.3 0.14 11.6 0.1 2.7 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KND87024.1 - 0.1 12.3 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 AraC-like ligand binding domain CFEM PF05730.6 KND87025.1 - 0.00032 20.4 1.7 0.00051 19.8 1.2 1.4 1 0 0 1 1 1 1 CFEM domain GPS PF01825.16 KND87025.1 - 0.09 12.8 0.3 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain LTP_2 PF14368.1 KND87025.1 - 2.2 8.5 6.4 0.47 10.6 1.6 1.9 1 1 1 2 2 2 0 Probable lipid transfer APH PF01636.18 KND87027.1 - 2e-07 30.9 0.5 1.7e-06 27.9 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND87027.1 - 0.0061 15.9 0.0 0.0086 15.4 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KND87027.1 - 0.0062 16.1 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Aminotran_5 PF00266.14 KND87028.1 - 5.7e-34 117.4 0.0 7.3e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Kelch_6 PF13964.1 KND87030.1 - 0.16 12.2 5.4 0.87 9.8 0.5 3.5 4 0 0 4 4 4 0 Kelch motif Pox_RNA_pol PF03293.9 KND87030.1 - 0.16 11.4 0.2 1.2 8.6 0.0 2.0 1 1 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Retrotrans_gag PF03732.12 KND87032.1 - 3.7e-06 26.9 0.0 8.5e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein OGG_N PF07934.7 KND87032.1 - 0.076 12.9 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Reo_sigmaC PF04582.7 KND87035.1 - 0.026 13.7 0.2 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Nsp1_C PF05064.8 KND87035.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region PAP2_C PF14360.1 KND87037.1 - 0.034 14.4 3.9 0.081 13.2 0.2 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF1774 PF08611.5 KND87038.1 - 5.7e-20 71.2 1.7 1e-19 70.4 0.1 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) SIT PF15330.1 KND87038.1 - 0.016 15.3 0.0 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT NfeD PF01957.13 KND87038.1 - 1.3 9.1 5.5 0.22 11.6 0.2 2.2 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding WD40 PF00400.27 KND87041.1 - 2.7e-35 118.9 5.8 4.6e-11 42.1 0.0 5.4 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 KND87041.1 - 0.0017 16.5 0.1 0.0092 14.1 0.1 1.9 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KND87041.1 - 0.0069 15.5 0.1 0.4 9.7 0.0 3.0 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KND87041.1 - 0.032 12.9 0.0 0.078 11.7 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Gmad1 PF10647.4 KND87041.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain AA_permease_2 PF13520.1 KND87042.1 - 1.7e-39 135.5 53.3 2.2e-39 135.2 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND87042.1 - 1.6e-25 89.3 50.0 2.1e-25 89.0 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease Cofilin_ADF PF00241.15 KND87043.1 - 1.7e-12 47.2 0.0 1.9e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CagE_TrbE_VirB PF03135.9 KND87043.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system HhH-GPD PF00730.20 KND87044.1 - 7.8e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KND87044.1 - 7.4e-14 51.1 0.0 1.6e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 KND87044.1 - 0.00083 18.9 0.1 0.0025 17.3 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KND87044.1 - 0.03 14.5 0.0 0.6 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3472 PF11958.3 KND87045.1 - 9e-12 45.7 0.4 1.3e-11 45.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) SBF PF01758.11 KND87046.1 - 1.6e-25 89.5 5.4 1.6e-25 89.5 3.7 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4137 PF13593.1 KND87046.1 - 4.2e-05 22.8 8.4 5.3e-05 22.4 5.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF63 PF01889.12 KND87046.1 - 0.092 12.8 11.4 0.88 9.5 0.7 2.1 1 1 1 2 2 2 0 Membrane protein of unknown function DUF63 Sugar_tr PF00083.19 KND87048.1 - 4.2e-09 35.4 0.4 1.8e-06 26.8 0.0 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter CBM_21 PF03370.8 KND87049.1 - 8.2e-35 119.2 0.1 1.7e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit APH PF01636.18 KND87050.1 - 2.2e-07 30.8 1.9 6.6e-06 26.0 1.3 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family XH PF03469.9 KND87050.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 XH domain Herpes_gE PF02480.11 KND87051.1 - 0.00057 18.2 0.7 0.0014 16.9 0.0 1.9 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KND87051.1 - 0.88 8.9 6.5 0.22 10.8 0.6 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain APH PF01636.18 KND87053.1 - 1.5e-21 77.2 0.1 1.9e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87053.1 - 7.2e-06 25.7 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND87053.1 - 4.8e-05 22.7 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KND87053.1 - 0.00047 19.4 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 KND87053.1 - 0.013 14.5 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_4 PF01565.18 KND87053.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain EcKinase PF02958.15 KND87053.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.11 KND87054.1 - 4.1e-22 78.3 33.5 4.1e-22 78.3 23.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.16 KND87055.1 - 8.5e-42 143.2 12.1 1.1e-39 136.3 8.4 2.2 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KND87055.1 - 3.7e-06 25.9 24.4 4.4e-05 22.3 7.2 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily p450 PF00067.17 KND87056.1 - 4.2e-57 193.6 0.0 1.3e-56 192.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Brix PF04427.13 KND87057.1 - 5.9e-44 150.0 0.1 7.6e-44 149.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain Glyco_hydro_47 PF01532.15 KND87058.1 - 1.9e-158 527.8 0.0 2.2e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_11 PF13414.1 KND87059.1 - 8.2e-59 195.1 26.8 2.5e-11 43.0 0.2 7.0 3 3 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 KND87059.1 - 1e-44 148.3 9.2 9.4e-06 25.0 0.0 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 KND87059.1 - 1.9e-43 142.9 8.4 0.00015 21.4 0.0 11.4 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 KND87059.1 - 4.7e-30 103.5 2.1 6.6e-07 29.8 0.0 6.2 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KND87059.1 - 8.1e-29 97.3 3.8 7.8e-05 22.5 0.0 9.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND87059.1 - 2.6e-26 91.3 14.8 4.3e-07 29.7 0.0 6.7 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 KND87059.1 - 3.8e-22 76.3 7.6 0.0055 16.4 0.2 9.5 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KND87059.1 - 1.1e-18 67.2 9.0 2.3e-06 27.8 0.7 5.6 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND87059.1 - 1.7e-18 65.4 6.2 9.8e-05 22.6 0.0 8.6 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 KND87059.1 - 1.2e-14 53.9 2.2 0.077 12.8 0.0 6.4 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KND87059.1 - 5.3e-11 41.4 9.6 0.032 14.0 0.1 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KND87059.1 - 9.4e-10 38.5 7.2 0.0054 16.8 0.3 5.4 2 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KND87059.1 - 4.8e-07 29.8 18.7 0.17 12.3 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KND87059.1 - 0.0001 21.4 1.4 0.85 8.9 0.0 4.6 4 0 0 4 4 4 1 SHNi-TPR DUF3856 PF12968.2 KND87059.1 - 0.0015 18.3 2.3 4.7 7.0 0.0 5.2 3 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) MAS20 PF02064.10 KND87059.1 - 0.0053 16.6 6.1 5.1 7.0 0.0 4.6 5 0 0 5 5 5 1 MAS20 protein import receptor NARP1 PF12569.3 KND87059.1 - 0.013 14.3 0.1 0.035 12.8 0.1 4.9 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 DUF1836 PF08876.6 KND87059.1 - 0.015 15.0 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) DUF2561 PF10812.3 KND87059.1 - 0.049 13.2 0.6 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TPR_20 PF14561.1 KND87059.1 - 0.068 13.2 11.3 2.3 8.4 0.3 4.7 5 2 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 KND87059.1 - 0.59 10.8 14.9 0.64 10.7 0.1 4.9 4 0 0 4 4 4 0 Sel1 repeat TPR_10 PF13374.1 KND87059.1 - 0.85 9.6 12.2 5.9 6.9 0.7 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KND87060.1 - 1.6e-07 31.1 0.0 4.4e-06 26.4 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND87060.1 - 0.00028 20.6 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sulfate_transp PF00916.15 KND87061.1 - 3.2e-49 167.4 3.7 3.2e-49 167.4 2.6 1.5 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KND87061.1 - 6.4e-28 96.2 3.2 2.3e-27 94.4 2.2 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KND87061.1 - 1.2e-17 63.3 0.0 2.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KND87061.1 - 0.00011 22.1 0.0 0.00043 20.2 0.0 2.1 1 1 0 1 1 1 1 STAS domain Thiolase_N PF00108.18 KND87062.1 - 5.2e-71 238.7 0.2 7.4e-71 238.2 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND87062.1 - 1.5e-39 134.1 1.9 1.7e-39 134.0 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KND87062.1 - 0.035 13.7 0.1 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KND87062.1 - 0.045 13.2 1.7 0.19 11.2 0.6 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Syntaxin PF00804.20 KND87063.1 - 5.7e-10 39.2 2.5 5.7e-10 39.2 1.7 2.7 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 KND87063.1 - 1.4e-08 34.3 7.3 1.4e-08 34.3 5.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 KND87063.1 - 0.0001 22.3 19.3 0.014 15.4 3.2 2.4 2 0 0 2 2 2 2 Syntaxin-like protein Prominin PF05478.6 KND87063.1 - 0.0012 16.5 0.4 0.0012 16.5 0.3 2.1 1 1 1 2 2 2 1 Prominin Use1 PF09753.4 KND87063.1 - 0.015 14.7 7.8 0.028 13.8 5.4 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Laminin_I PF06008.9 KND87063.1 - 0.059 12.6 14.3 0.52 9.5 0.8 2.4 2 1 0 2 2 2 0 Laminin Domain I DUF2077 PF09850.4 KND87063.1 - 0.061 12.7 2.3 0.075 12.4 0.3 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2562 PF10814.3 KND87063.1 - 0.07 13.0 1.1 0.14 12.0 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) BatA PF07584.6 KND87063.1 - 0.11 12.7 0.1 0.29 11.3 0.0 1.7 2 0 0 2 2 1 0 Aerotolerance regulator N-terminal ETRAMP PF09716.5 KND87063.1 - 0.12 12.2 0.3 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) AF0941-like PF14591.1 KND87063.1 - 0.26 11.3 7.7 1.3 9.1 1.0 2.8 2 1 1 3 3 3 0 AF0941-like Tropomyosin_1 PF12718.2 KND87063.1 - 0.47 10.3 15.0 1.1 9.1 0.6 2.6 2 1 0 2 2 2 0 Tropomyosin like DUF3708 PF12501.3 KND87063.1 - 0.52 10.1 4.2 0.62 9.8 0.7 2.3 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter Tweety PF04906.8 KND87063.1 - 0.56 8.5 8.0 3 6.1 0.3 2.4 1 1 1 2 2 2 0 Tweety FH2 PF02181.18 KND87063.1 - 0.77 8.5 6.8 5 5.9 0.7 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Mod_r PF07200.8 KND87063.1 - 1.1 9.1 15.7 2.5 8.0 2.8 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Allexi_40kDa PF05549.6 KND87063.1 - 1.8 7.7 8.8 0.62 9.3 0.7 2.4 1 1 2 3 3 3 0 Allexivirus 40kDa protein DivIC PF04977.10 KND87063.1 - 1.9 8.0 0.0 1.9 8.0 0.0 4.3 4 1 0 4 4 3 0 Septum formation initiator Lge1 PF11488.3 KND87063.1 - 2.4 8.4 8.1 0.4 10.8 1.4 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Fib_alpha PF08702.5 KND87063.1 - 2.7 8.1 16.0 2.5 8.1 3.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_C6 PF00851.13 KND87063.1 - 3.7 6.0 11.4 0.79 8.2 1.3 2.0 1 1 1 2 2 2 0 Helper component proteinase DUF2203 PF09969.4 KND87063.1 - 4.8 7.4 9.0 1.6 8.9 1.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ATP-synt_B PF00430.13 KND87063.1 - 5.3 6.8 15.8 2.4 7.9 6.1 2.8 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) RasGAP_C PF03836.10 KND87063.1 - 8.1 6.1 12.3 0.14 11.8 1.8 2.4 2 1 0 2 2 2 0 RasGAP C-terminus RP-C_C PF11800.3 KND87063.1 - 8.7 5.9 13.8 0.57 9.8 3.2 2.7 1 1 1 2 2 2 0 Replication protein C C-terminal region Aminotran_4 PF01063.14 KND87064.1 - 1.6e-23 83.4 0.0 1.9e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Sulfate_transp PF00916.15 KND87065.1 - 3.9e-76 255.7 9.5 7.1e-76 254.8 6.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KND87065.1 - 1.5e-31 107.8 2.9 1.5e-31 107.8 2.0 3.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KND87065.1 - 7.7e-09 34.9 0.0 1.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain Glyco_hydro_17 PF00332.13 KND87066.1 - 3.9e-05 22.8 0.8 7.3e-05 21.9 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 ShlB PF03865.8 KND87066.1 - 0.06 12.0 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Glyco_hydro_cc PF11790.3 KND87067.1 - 6e-68 228.8 0.3 7e-68 228.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.15 KND87068.1 - 5e-64 215.4 1.8 1e-63 214.4 1.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND87068.1 - 1.7e-34 118.9 3.1 1.7e-34 118.9 2.2 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND87068.1 - 4.9e-28 99.0 0.0 8.5e-27 94.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND87068.1 - 4.4e-22 77.8 0.0 1.4e-21 76.1 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KND87068.1 - 9e-14 50.6 0.0 2.7e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KND87068.1 - 2.1e-12 47.5 0.0 5.4e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND87068.1 - 2.7e-07 30.4 0.3 1.4e-05 24.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3733 PF12534.3 KND87068.1 - 0.028 13.6 0.4 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Transp_cyt_pur PF02133.10 KND87069.1 - 4.2e-53 180.4 29.5 1.5e-39 135.8 9.1 3.2 3 0 0 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 KND87069.1 - 1.3e-23 83.2 0.2 2e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-HC5HC2H PF13771.1 KND87069.1 - 0.057 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Thi4 PF01946.12 KND87071.1 - 5.1e-108 359.4 0.2 7.1e-108 359.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KND87071.1 - 1.1e-07 31.1 0.1 2.1e-06 26.9 0.4 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KND87071.1 - 2.2e-05 23.5 0.4 9.4e-05 21.4 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KND87071.1 - 7.1e-05 22.7 0.2 0.00019 21.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND87071.1 - 0.00017 21.3 0.5 0.00073 19.3 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND87071.1 - 0.00047 20.2 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND87071.1 - 0.00076 18.4 3.0 0.013 14.3 0.5 2.8 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KND87071.1 - 0.001 18.9 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND87071.1 - 0.0052 15.9 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND87071.1 - 0.04 12.3 0.4 0.056 11.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KND87071.1 - 0.085 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KND87071.1 - 0.09 11.3 0.2 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF917 PF06032.7 KND87072.1 - 9.9e-109 363.1 0.0 2e-108 362.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KND87072.1 - 1.1e-45 156.0 5.2 1.1e-45 156.0 3.6 2.6 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KND87072.1 - 1.3e-29 102.9 2.1 2.2e-26 92.4 0.0 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KND87072.1 - 0.00016 20.1 2.7 0.079 11.2 0.0 2.4 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 KND87072.1 - 0.00027 20.0 0.3 0.51 9.2 0.0 2.5 2 0 0 2 2 2 2 StbA protein DUF3663 PF12404.3 KND87072.1 - 0.041 13.6 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase APH PF01636.18 KND87073.1 - 2.7e-08 33.8 0.6 3.7e-08 33.3 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pro_CA PF00484.14 KND87075.1 - 2e-49 167.5 0.0 2.7e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Lyase_8 PF02278.13 KND87076.1 - 8.2e-30 104.0 1.6 8.2e-30 104.0 1.1 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KND87076.1 - 2.8e-24 85.6 0.1 4.7e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Isochorismatase PF00857.15 KND87077.1 - 2.5e-24 86.1 0.0 3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Ank PF00023.25 KND87077.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat ThiW PF09512.5 KND87078.1 - 0.031 14.1 8.8 0.015 15.1 2.8 2.5 2 1 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Myb_DNA-bind_3 PF12776.2 KND87079.1 - 3.9e-19 69.0 0.1 6.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2985 PF11204.3 KND87081.1 - 8.3e-28 95.9 4.3 1.4e-27 95.2 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) MFS_1 PF07690.11 KND87083.1 - 2e-51 174.7 18.0 2e-51 174.7 12.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND87083.1 - 2e-12 46.4 4.8 2e-12 46.4 3.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KND87083.1 - 7.8e-08 30.9 5.4 1.2e-07 30.3 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KND87083.1 - 0.00045 18.4 3.7 0.00045 18.4 2.6 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.3 KND87083.1 - 0.0009 17.8 0.9 0.0009 17.8 0.6 3.3 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like UCR_Fe-S_N PF10399.4 KND87083.1 - 0.015 14.4 4.7 1.9 7.7 0.5 3.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF791 PF05631.9 KND87083.1 - 0.032 12.9 4.4 0.093 11.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF791) PgaD PF13994.1 KND87083.1 - 0.57 9.6 2.8 0.99 8.8 0.0 2.7 3 0 0 3 3 3 0 PgaD-like protein V-SNARE_C PF12352.3 KND87084.1 - 3.9e-14 52.4 1.6 1.7e-13 50.4 0.1 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KND87084.1 - 2.3e-06 27.1 0.1 2e-05 24.2 0.0 2.3 2 1 1 3 3 3 1 Sec20 KxDL PF10241.4 KND87084.1 - 0.0015 18.3 1.4 0.16 11.8 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein Cortex-I_coil PF09304.5 KND87084.1 - 0.031 14.3 1.4 5.7 7.0 0.0 2.8 2 1 1 3 3 3 0 Cortexillin I, coiled coil Cytochrom_B562 PF07361.6 KND87084.1 - 0.098 13.0 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Cytochrome b562 DivIC PF04977.10 KND87084.1 - 0.32 10.5 2.0 1.9 8.0 0.0 2.9 2 1 1 3 3 3 0 Septum formation initiator TPK_catalytic PF04263.11 KND87085.1 - 2e-22 79.0 0.0 2.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KND87085.1 - 7.8e-22 76.7 0.1 1.2e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Cas_csx3 PF09620.5 KND87086.1 - 0.066 13.0 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) G_glu_transpept PF01019.16 KND87087.1 - 5e-159 530.0 0.8 6.2e-159 529.7 0.6 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase 4HBT_2 PF13279.1 KND87088.1 - 5.4e-22 78.4 0.1 9.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ADH_zinc_N PF00107.21 KND87089.1 - 3.4e-21 75.1 0.0 5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3139 PF11337.3 KND87090.1 - 0.0027 17.9 0.1 0.0057 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) FmdA_AmdA PF03069.10 KND87091.1 - 1.3e-152 507.8 0.0 1.6e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family B3_4 PF03483.12 KND87091.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain Glyco_hydro_16 PF00722.16 KND87092.1 - 7.6e-18 64.4 0.8 1.2e-17 63.8 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KND87092.1 - 6.6e-05 21.2 4.2 0.01 14.0 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.11 KND87093.1 - 3.7e-25 88.3 29.4 9.6e-25 87.0 19.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Serglycin PF04360.7 KND87093.1 - 0.0076 15.9 2.3 0.021 14.5 1.6 1.7 1 0 0 1 1 1 1 Serglycin Tetraspannin PF00335.15 KND87094.1 - 4.7e-07 29.3 0.7 1.1e-06 28.1 0.5 1.5 1 1 0 1 1 1 1 Tetraspanin family Endostatin PF06482.6 KND87094.1 - 0.052 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Asp PF00026.18 KND87096.1 - 6.7e-65 219.4 0.7 8.1e-65 219.1 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KND87096.1 - 6.1e-05 23.4 2.8 0.05 14.1 0.6 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KND87096.1 - 0.00039 20.4 0.0 0.0031 17.4 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Cytomega_UL20A PF05984.7 KND87096.1 - 0.067 13.3 1.0 0.88 9.8 0.1 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Ldh_1_C PF02866.13 KND87097.1 - 2.1e-44 151.3 0.0 3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KND87097.1 - 2e-43 147.6 0.1 1e-42 145.2 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KND87097.1 - 0.019 13.7 0.0 0.027 13.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KND87097.1 - 0.13 12.5 0.6 0.66 10.2 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain zf-C2HC5 PF06221.8 KND87098.1 - 7.4e-22 76.8 5.4 1.2e-21 76.2 3.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAM176 PF14851.1 KND87098.1 - 0.14 11.8 1.5 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 FAM176 family DNA_pol_A_exo1 PF01612.15 KND87099.1 - 0.0061 16.0 0.4 0.011 15.1 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease RNase_T PF00929.19 KND87099.1 - 0.02 15.2 0.3 0.02 15.2 0.2 1.6 2 0 0 2 2 2 0 Exonuclease Hydrolase PF00702.21 KND87100.1 - 2.3e-22 80.4 0.0 1.6e-21 77.7 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND87100.1 - 7.2e-21 75.2 0.1 1.7e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KND87100.1 - 9.3e-19 67.3 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KND87100.1 - 0.00045 20.1 0.0 0.00045 20.1 0.0 2.0 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND87100.1 - 0.0039 16.8 0.0 0.07 12.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND87100.1 - 0.031 13.7 0.0 0.099 12.1 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF4059 PF13268.1 KND87100.1 - 0.085 13.0 1.2 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) SIR2 PF02146.12 KND87101.1 - 2e-31 109.0 0.1 3.4e-10 39.9 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Aminotran_5 PF00266.14 KND87102.1 - 4.4e-22 78.3 0.0 5.6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TGS PF02824.16 KND87102.1 - 0.026 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 TGS domain Pyridoxal_deC PF00282.14 KND87102.1 - 0.059 11.8 0.0 0.087 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Whi5 PF08528.6 KND87103.1 - 8.2e-09 34.8 0.0 1.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Whi5 like PALP PF00291.20 KND87104.1 - 2.1e-30 105.9 0.0 3.9e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 KND87104.1 - 7.3e-07 29.5 0.0 4.8e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Rhodanese-like domain Toprim_2 PF13155.1 KND87104.1 - 0.075 13.3 0.0 4 7.8 0.0 2.7 2 0 0 2 2 2 0 Toprim-like UPF1_Zn_bind PF09416.5 KND87105.1 - 6.4e-70 233.6 6.0 5.7e-69 230.5 2.1 2.9 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KND87105.1 - 1e-59 201.3 0.0 2e-59 200.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND87105.1 - 1.9e-57 194.5 3.2 3e-57 193.9 2.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND87105.1 - 2.2e-14 52.9 0.7 5.4e-14 51.7 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KND87105.1 - 1.2e-12 47.8 0.8 6.7e-11 42.1 0.6 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KND87105.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KND87105.1 - 1.9e-05 24.3 0.3 0.11 11.9 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KND87105.1 - 6.6e-05 22.0 0.9 0.00073 18.6 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KND87105.1 - 9.8e-05 22.0 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KND87105.1 - 0.00011 21.3 0.3 0.18 10.7 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.16 KND87105.1 - 0.00011 21.6 0.1 0.0027 17.0 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain KaiC PF06745.8 KND87105.1 - 0.00024 20.3 0.0 0.0022 17.1 0.0 2.1 2 0 0 2 2 2 1 KaiC DEAD PF00270.24 KND87105.1 - 0.00028 20.4 0.3 0.00064 19.2 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 KND87105.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain SRP54 PF00448.17 KND87105.1 - 0.012 15.1 0.1 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 KND87105.1 - 0.015 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KND87105.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KND87105.1 - 0.037 13.2 0.0 0.093 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein CbiA PF01656.18 KND87105.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KND87105.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KND87105.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KND87105.1 - 0.12 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 KND87105.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Fungal_trans_2 PF11951.3 KND87106.1 - 1.1e-54 185.5 3.7 1.5e-54 185.0 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87106.1 - 1e-07 31.7 7.1 2.2e-07 30.6 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 KND87107.1 - 1.5e-33 115.7 0.0 2e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AA_permease_2 PF13520.1 KND87108.1 - 2.2e-52 178.0 48.4 2.7e-52 177.7 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND87108.1 - 2.5e-31 108.5 41.4 3.3e-31 108.1 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease SecG PF03840.9 KND87108.1 - 0.3 10.8 0.0 0.3 10.8 0.0 4.3 5 1 0 5 5 5 0 Preprotein translocase SecG subunit Dicty_CAR PF05462.6 KND87109.1 - 2.9e-11 42.8 5.7 3.8e-11 42.4 3.9 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KND87109.1 - 1.2e-07 31.1 8.5 2e-07 30.3 5.9 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.12 KND87109.1 - 0.0031 16.3 8.4 0.57 8.9 5.8 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Git3 PF11710.3 KND87109.1 - 0.022 14.3 11.0 0.1 12.1 7.6 2.0 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 GMC_oxred_N PF00732.14 KND87110.1 - 3.1e-58 197.2 0.0 4.1e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND87110.1 - 5.1e-30 104.6 0.0 8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND87110.1 - 0.00022 20.1 0.5 0.026 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KND87110.1 - 0.008 15.1 0.2 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein MFS_1 PF07690.11 KND87111.1 - 1.6e-06 27.1 6.7 2.3e-06 26.5 4.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND87111.1 - 0.00038 19.1 4.1 0.00038 19.1 2.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_5 PF06946.6 KND87111.1 - 0.065 13.4 0.8 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Phage holin Ank_2 PF12796.2 KND87112.1 - 3e-51 171.6 0.2 1.3e-18 67.0 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KND87112.1 - 1.5e-48 160.2 0.0 3e-09 36.2 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KND87112.1 - 4.1e-36 122.2 1.0 3.4e-09 36.6 0.0 5.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87112.1 - 4.2e-36 119.3 0.0 1.8e-07 30.7 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KND87112.1 - 2.5e-35 120.2 4.5 2.9e-10 40.3 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) PhoD PF09423.5 KND87112.1 - 0.066 11.7 0.2 0.081 11.4 0.1 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase Sugar_tr PF00083.19 KND87113.1 - 1.9e-74 250.8 27.3 2.3e-74 250.6 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND87113.1 - 3.1e-15 55.7 35.3 5.4e-15 54.9 20.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND87113.1 - 9e-05 21.0 30.1 0.00026 19.5 2.8 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein UNC-93 PF05978.11 KND87114.1 - 6.9e-11 41.8 9.3 6.9e-11 41.8 6.5 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KND87114.1 - 4.5e-10 38.7 44.2 4.5e-10 38.7 30.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PrgI PF12666.2 KND87114.1 - 0.26 11.4 0.0 0.26 11.4 0.0 4.4 5 0 0 5 5 5 0 PrgI family protein DUF805 PF05656.9 KND87114.1 - 0.76 9.6 0.0 0.76 9.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF805) Na_Ca_ex PF01699.19 KND87115.1 - 6.7e-34 116.4 31.5 2.5e-18 66.0 7.6 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p450 PF00067.17 KND87116.1 - 2.3e-32 112.1 0.0 3.9e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KND87117.1 - 4.1e-43 147.5 0.0 5.6e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KND87118.1 - 1.6e-06 27.6 0.1 3.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND87118.1 - 2.7e-06 27.0 0.3 6e-06 25.9 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 KND87119.1 - 4.8e-88 295.3 0.0 7.9e-88 294.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KND87119.1 - 9.9e-73 244.7 0.0 2.1e-72 243.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND87119.1 - 2.3e-52 178.3 0.0 4.5e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KND87119.1 - 4.8e-51 173.6 3.8 9e-51 172.7 2.6 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 KND87119.1 - 2.4e-46 157.9 0.0 3.6e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 KND87119.1 - 2.7e-41 141.2 0.1 1.2e-40 139.1 0.0 2.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KND87119.1 - 2.9e-33 115.1 0.0 3.8e-32 111.5 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND87119.1 - 3e-32 110.9 1.1 4.4e-32 110.4 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KND87119.1 - 1.7e-23 82.8 0.0 9.6e-23 80.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KND87119.1 - 6.2e-18 65.1 0.0 1.5e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KND87119.1 - 3.4e-17 62.4 1.1 1.3e-09 38.1 0.0 3.2 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KND87119.1 - 1.8e-12 47.2 0.0 4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KND87119.1 - 4.1e-11 43.0 0.0 1.1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 KND87119.1 - 7.2e-10 39.2 0.0 1.7e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KND87119.1 - 1.2e-08 34.7 0.0 2.7e-07 30.2 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KND87119.1 - 4.2e-08 33.7 0.0 1.5e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 KND87119.1 - 9.7e-08 32.8 2.2 2.7e-07 31.4 0.3 3.0 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 KND87119.1 - 5.3e-07 29.3 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND87119.1 - 3.9e-05 22.8 0.0 8.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KND87119.1 - 4.7e-05 22.4 0.0 9.2e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 KND87119.1 - 0.035 13.1 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 KND87119.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_PK PF05891.7 KND87119.1 - 0.66 9.2 0.0 1.3 8.2 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Fungal_trans PF04082.13 KND87121.1 - 3.9e-13 48.8 0.2 7.1e-13 48.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87121.1 - 3.3e-08 33.2 12.1 7.4e-08 32.1 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KND87122.1 - 1.3e-09 37.7 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KND87122.1 - 4.7e-06 26.5 0.3 3.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KND87122.1 - 0.0056 15.9 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.1 KND87122.1 - 0.039 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain IL4 PF00727.13 KND87122.1 - 0.1 12.4 0.3 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Interleukin 4 p450 PF00067.17 KND87123.1 - 1e-58 199.0 0.0 1.2e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GRAM PF02893.15 KND87124.1 - 6.2e-24 83.2 0.2 3.2e-12 45.7 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KND87124.1 - 2.5e-23 82.3 0.0 8e-23 80.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Transpep_BrtH PF14399.1 KND87124.1 - 3.5e-20 72.5 0.0 5.7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase PH PF00169.24 KND87124.1 - 3.5e-11 43.2 0.0 8.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 KND87124.1 - 1.6e-05 23.7 0.0 2.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 KND87124.1 - 1.7e-05 24.8 0.1 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KND87124.1 - 0.00086 19.5 0.2 0.0032 17.7 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Transaldolase PF00923.14 KND87125.1 - 1e-30 106.8 0.0 1.5e-30 106.3 0.0 1.4 1 1 0 1 1 1 1 Transaldolase Acetyltransf_7 PF13508.1 KND87126.1 - 1.9e-13 50.3 0.1 3e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND87126.1 - 4.4e-11 42.6 0.0 6.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND87126.1 - 6.3e-07 29.5 0.0 7.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND87126.1 - 7.7e-06 25.9 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND87126.1 - 9.3e-05 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND87126.1 - 0.00036 20.7 0.0 0.00045 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND87126.1 - 0.028 14.1 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein DndB PF14072.1 KND87128.1 - 0.0018 17.4 0.0 0.0054 15.9 0.0 1.6 1 1 0 1 1 1 1 DNA-sulfur modification-associated FAD_binding_4 PF01565.18 KND87129.1 - 3.3e-19 68.7 2.4 7.4e-19 67.5 1.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND87129.1 - 1.4e-10 40.8 0.2 3e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KND87129.1 - 0.0051 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding EVI2A PF05399.6 KND87130.1 - 0.44 9.7 2.0 3.6 6.7 0.6 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Cu-oxidase_3 PF07732.10 KND87131.1 - 5.6e-40 135.7 1.1 1.5e-38 131.1 0.1 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND87131.1 - 5.9e-32 110.0 5.3 3.5e-31 107.5 0.4 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KND87131.1 - 5.1e-18 65.4 0.0 7.1e-16 58.4 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase EHN PF06441.7 KND87133.1 - 1.2e-38 131.5 0.6 2.3e-37 127.3 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KND87133.1 - 1.2e-12 48.2 0.2 2.7e-12 47.0 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND87133.1 - 0.00039 20.0 0.3 0.00096 18.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold APH PF01636.18 KND87134.1 - 8.6e-15 55.1 0.5 1.2e-14 54.6 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87134.1 - 0.0032 17.0 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase OPT PF03169.10 KND87135.1 - 7.4e-187 622.5 45.2 8.4e-187 622.3 31.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Na_Ca_ex PF01699.19 KND87136.1 - 4.2e-27 94.4 27.6 3.7e-14 52.5 11.6 2.8 2 1 0 2 2 2 2 Sodium/calcium exchanger protein E1-E2_ATPase PF00122.15 KND87137.1 - 2.4e-109 363.7 8.7 1.5e-55 187.7 0.0 3.0 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND87137.1 - 6.4e-76 253.9 25.3 1.8e-42 144.9 7.1 4.9 5 0 0 5 5 5 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND87137.1 - 8.5e-59 199.5 0.1 6.5e-28 98.6 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND87137.1 - 6.7e-38 128.5 0.0 2.5e-20 72.2 0.0 3.0 2 0 0 2 2 2 2 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KND87137.1 - 1.9e-32 113.0 0.0 8.6e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Na_Ca_ex PF01699.19 KND87137.1 - 4e-16 58.8 24.3 1e-09 38.1 6.1 5.5 7 0 0 7 7 7 2 Sodium/calcium exchanger protein Cation_ATPase_N PF00690.21 KND87137.1 - 2.5e-11 42.8 0.1 0.00042 19.7 0.0 3.8 3 0 0 3 3 3 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KND87137.1 - 1.9e-08 34.2 3.6 0.0014 18.2 0.1 3.4 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KND87137.1 - 0.093 12.6 0.0 19 5.2 0.0 2.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Metallopep PF12044.3 KND87139.1 - 3.3e-98 328.9 0.0 3.8e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.1 KND87139.1 - 0.0034 17.3 0.3 0.0078 16.1 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KND87139.1 - 0.0045 16.5 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KND87139.1 - 0.0055 16.7 0.1 0.0093 16.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KND87139.1 - 0.012 16.1 0.4 0.044 14.3 0.1 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Gly_transf_sug PF04488.10 KND87140.1 - 1.1e-06 28.9 0.2 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KND87140.1 - 0.048 12.1 0.5 0.2 10.1 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.11 KND87144.1 - 1.4e-13 50.3 54.6 5.8e-12 44.9 37.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CcmD PF04995.9 KND87144.1 - 0.024 14.3 1.3 0.15 11.8 0.9 2.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pox_A14 PF05767.7 KND87144.1 - 0.76 9.7 8.2 0.098 12.6 0.2 3.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 CFEM PF05730.6 KND87145.1 - 1.6e-07 31.0 5.3 2.6e-07 30.3 3.7 1.3 1 0 0 1 1 1 1 CFEM domain KAR9 PF08580.5 KND87145.1 - 0.015 13.5 5.8 0.018 13.3 4.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_M28 PF04389.12 KND87148.1 - 2.5e-38 131.6 0.0 4.9e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KND87148.1 - 9.2e-12 44.5 0.2 6e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KND87148.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KND87149.1 - 8.2e-15 54.0 2.9 0.00089 19.0 0.2 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Cupin_2 PF07883.6 KND87150.1 - 0.054 13.0 1.7 6.2 6.4 0.0 3.3 3 0 0 3 3 3 0 Cupin domain PMI_typeI PF01238.16 KND87150.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Phosphomannose isomerase type I Pkinase PF00069.20 KND87151.1 - 0.0006 19.0 0.2 0.0017 17.5 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KND87151.1 - 0.004 16.7 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KND87151.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND87151.1 - 0.078 12.6 0.1 0.078 12.6 0.0 2.8 2 1 0 3 3 3 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 KND87152.1 - 3.4e-18 65.4 0.0 7.2e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87152.1 - 3.1e-08 33.4 13.9 3.1e-08 33.4 9.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-P11 PF03854.9 KND87152.1 - 0.11 11.9 4.4 0.16 11.4 0.7 2.7 2 0 0 2 2 2 0 P-11 zinc finger ADH_N PF08240.7 KND87153.1 - 8.4e-29 99.5 0.7 1.8e-28 98.4 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND87153.1 - 2.7e-19 68.9 0.1 4.9e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KND87153.1 - 0.00011 21.8 0.7 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KND87153.1 - 0.00059 20.7 0.0 0.0027 18.5 0.0 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KND87153.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CMV_1a PF12467.3 KND87154.1 - 0.22 11.9 3.5 2.4 8.5 0.0 2.5 2 1 0 2 2 2 0 Cucumber mosaic virus 1a protein family MFS_1 PF07690.11 KND87155.1 - 1.5e-21 76.5 36.7 2e-19 69.5 13.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KND87156.1 - 5.5e-117 390.9 0.0 6.2e-66 222.6 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fungal_trans PF04082.13 KND87157.1 - 2.1e-28 98.9 3.2 3.4e-28 98.2 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87157.1 - 2.6e-06 27.2 7.9 2.6e-06 27.2 5.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_transf_sug PF04488.10 KND87159.1 - 4.4e-06 27.0 0.0 1.4e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif F-box PF00646.28 KND87160.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain Gly_transf_sug PF04488.10 KND87162.1 - 2.8e-10 40.5 0.0 6.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PIG-L PF02585.12 KND87163.1 - 2.4e-20 73.3 0.0 3.6e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2592 PF10766.4 KND87163.1 - 0.79 9.1 2.3 0.92 8.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) adh_short PF00106.20 KND87164.1 - 4.6e-07 29.9 4.9 1.7e-06 28.0 3.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND87164.1 - 7.2e-05 22.6 0.4 0.00011 22.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B_2 PF12706.2 KND87165.1 - 1.7e-22 79.9 0.0 2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KND87165.1 - 2.8e-13 49.9 0.0 4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MacB_PCD PF12704.2 KND87165.1 - 0.056 13.0 0.0 2.9 7.3 0.0 2.2 1 1 0 2 2 2 0 MacB-like periplasmic core domain Phosphoesterase PF04185.9 KND87166.1 - 1.8e-77 261.0 0.2 2.6e-77 260.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.1 KND87166.1 - 0.033 14.5 0.1 0.17 12.2 0.1 2.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like PAXIP1_C PF15364.1 KND87167.1 - 0.11 12.4 0.3 0.12 12.3 0.2 1.0 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Methyltransf_2 PF00891.13 KND87168.1 - 3.1e-21 75.6 0.0 1.1e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 KND87168.1 - 0.088 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FAD_binding_2 PF00890.19 KND87170.1 - 4.4e-66 223.4 0.2 4.9e-66 223.3 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KND87171.1 - 5.3e-19 68.3 0.0 6.1e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND87171.1 - 2.9e-06 27.1 0.1 5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KND87171.1 - 0.00017 20.7 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KND87171.1 - 0.00028 20.0 0.1 0.00034 19.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KND87171.1 - 0.00035 19.5 0.0 0.00039 19.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KND87171.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND87171.1 - 0.0055 16.7 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND87171.1 - 0.0096 14.4 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KND87171.1 - 0.022 13.6 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KND87171.1 - 0.078 11.8 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.11 KND87173.1 - 3.2e-34 118.2 43.6 1.8e-30 105.8 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TAT_signal PF10518.4 KND87173.1 - 8 6.7 9.2 7.3 6.8 2.3 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Clp1 PF06807.9 KND87174.1 - 8.1e-22 77.9 0.0 1.2e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KND87174.1 - 1.6e-08 34.3 0.0 5.5e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 KND87174.1 - 7.3e-06 25.3 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 KND87174.1 - 2.3e-05 24.3 0.0 0.00011 22.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 KND87174.1 - 0.00011 21.8 0.6 0.01 15.5 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KND87174.1 - 0.00014 22.6 0.0 0.013 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND87174.1 - 0.00019 21.4 0.0 0.0011 18.9 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 KND87174.1 - 0.00087 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KND87174.1 - 0.0035 17.6 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KND87174.1 - 0.0038 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KND87174.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 KND87174.1 - 0.018 14.2 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 KND87174.1 - 0.025 13.6 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 KND87174.1 - 0.039 14.1 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KND87174.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KND87174.1 - 0.1 11.9 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KND87174.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KND87174.1 - 0.14 11.7 0.1 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND87174.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KND87174.1 - 0.14 12.0 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.15 KND87175.1 - 2.1e-58 197.0 4.4 5e-58 195.8 3.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND87175.1 - 7.7e-34 116.7 1.1 7.7e-34 116.7 0.8 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND87175.1 - 2.8e-33 116.1 0.1 8.7e-32 111.2 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND87175.1 - 1.1e-18 66.4 0.0 2.6e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KND87175.1 - 1.5e-12 47.3 0.0 2.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KND87175.1 - 2.4e-12 47.4 1.3 6.1e-12 46.0 0.5 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND87175.1 - 1.5e-06 27.9 0.2 0.00018 21.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3650 PF12368.3 KND87175.1 - 0.054 12.9 0.4 0.9 9.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Zip PF02535.17 KND87176.1 - 1.4e-49 168.8 2.3 1.7e-49 168.6 1.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 KND87176.1 - 0.072 12.2 0.6 0.21 10.7 0.1 1.9 2 0 0 2 2 2 0 UNC-50 family DUF805 PF05656.9 KND87176.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.6 4 1 0 4 4 4 0 Protein of unknown function (DUF805) Beta-lactamase PF00144.19 KND87177.1 - 2.5e-42 145.0 0.4 3.2e-42 144.7 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KND87177.1 - 8.1e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) MTBP_mid PF14919.1 KND87178.1 - 0.074 11.7 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding APH PF01636.18 KND87179.1 - 1.4e-16 60.9 0.0 3.8e-16 59.5 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND87179.1 - 8.8e-05 21.9 0.1 0.003 16.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 KND87179.1 - 0.0003 19.8 0.0 0.0033 16.4 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase Choline_kinase PF01633.15 KND87179.1 - 0.0011 18.5 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KND87179.1 - 0.0034 16.0 0.0 0.037 12.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 KND87180.1 - 0.05 12.7 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Abhydrolase_5 PF12695.2 KND87182.1 - 6.1e-14 52.0 0.0 4.6e-12 45.9 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND87182.1 - 5e-12 46.1 0.1 1.7e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KND87182.1 - 3.7e-06 26.3 0.0 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF1100 PF06500.6 KND87182.1 - 2.1e-05 23.2 0.0 3.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 KND87182.1 - 0.00019 20.7 0.1 0.0039 16.4 0.0 2.1 1 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KND87182.1 - 0.00042 20.0 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 KND87182.1 - 0.0028 16.2 0.1 0.02 13.3 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KND87182.1 - 0.094 12.1 0.0 0.69 9.3 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF1977 PF09320.6 KND87182.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) Abhydrolase_1 PF00561.15 KND87182.1 - 0.11 11.9 1.0 0.4 10.1 0.1 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.13 KND87183.1 - 4e-08 33.0 11.1 5.8e-08 32.5 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND87183.1 - 0.0051 15.4 0.3 0.007 15.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATase PF00117.23 KND87184.1 - 1.9e-10 40.4 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KND87184.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KND87184.1 - 0.18 11.1 0.2 1.3 8.3 0.1 2.2 1 1 0 1 1 1 0 Peptidase C26 Git3 PF11710.3 KND87185.1 - 3.7e-45 153.9 13.0 1.3e-44 152.1 9.0 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KND87185.1 - 3.5e-17 61.9 0.2 3.5e-17 61.9 0.2 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2215 PF10225.4 KND87185.1 - 0.82 9.0 4.9 0.39 10.1 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) p450 PF00067.17 KND87186.1 - 3.3e-23 81.9 0.0 2.1e-16 59.5 0.0 3.6 2 1 1 3 3 3 3 Cytochrome P450 Abhydrolase_6 PF12697.2 KND87186.1 - 0.00011 22.1 0.1 0.0014 18.5 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND87186.1 - 0.018 14.7 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ldr_toxin PF13940.1 KND87186.1 - 0.094 12.4 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system ketoacyl-synt PF00109.21 KND87187.1 - 2.9e-74 249.7 0.0 3.7e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KND87187.1 - 1e-25 89.9 0.1 2.5e-25 88.6 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KND87187.1 - 0.00027 19.9 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KND87187.1 - 0.048 13.3 0.2 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2236 PF09995.4 KND87188.1 - 6.4e-29 100.9 0.1 7.9e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) BNR PF02012.15 KND87190.1 - 0.015 15.0 0.1 0.13 12.2 0.0 2.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo-co_dimer PF03404.11 KND87190.1 - 0.071 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain peroxidase PF00141.18 KND87191.1 - 1.1e-85 286.7 0.1 4e-43 147.5 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Glyco_hydro_2_N PF02837.13 KND87192.1 - 2e-28 99.0 0.5 4e-28 98.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KND87192.1 - 8.7e-11 41.2 0.0 1.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KND87192.1 - 4e-09 36.8 0.1 1.2e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KND87192.1 - 0.044 14.0 0.3 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Pkinase PF00069.20 KND87193.1 - 0.0011 18.2 0.0 0.0031 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KND87193.1 - 0.0051 16.5 0.0 0.0051 16.5 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87193.1 - 0.017 14.7 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF874 PF05917.6 KND87193.1 - 0.51 9.1 8.1 0.81 8.4 5.6 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) eIF3_subunit PF08597.5 KND87193.1 - 1.7 8.1 11.0 3.5 7.1 7.6 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Mnd1 PF03962.10 KND87193.1 - 3.4 7.2 6.7 6.3 6.4 4.7 1.4 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 KND87193.1 - 8.3 6.3 10.2 18 5.2 7.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_16 PF13191.1 KND87194.1 - 2.1e-10 40.8 0.0 7.5e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KND87194.1 - 8.9e-08 31.9 0.1 2.4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 KND87194.1 - 0.00019 21.4 0.0 0.00056 19.8 0.0 1.8 2 0 0 2 2 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KND87194.1 - 0.00028 21.0 0.0 0.0009 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 KND87194.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KND87194.1 - 0.0042 16.4 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_14 PF13173.1 KND87194.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Abhydrolase_5 PF12695.2 KND87194.1 - 0.005 16.5 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_tran PF00005.22 KND87194.1 - 0.0057 16.9 0.0 0.045 14.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 KND87194.1 - 0.0082 15.8 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KND87194.1 - 0.011 16.5 0.3 0.057 14.2 0.1 2.4 2 1 0 2 2 1 0 AAA domain AAA PF00004.24 KND87194.1 - 0.015 15.5 0.0 0.68 10.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cutinase PF01083.17 KND87194.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Cutinase AAA_10 PF12846.2 KND87194.1 - 0.022 14.2 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KND87194.1 - 0.04 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KND87194.1 - 0.043 14.1 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 KND87194.1 - 0.052 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KND87194.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KND87194.1 - 0.073 12.0 0.4 0.68 8.8 0.3 2.1 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KND87194.1 - 0.082 12.4 0.0 0.41 10.2 0.0 2.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KND87194.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 KND87194.1 - 0.16 12.1 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase LCAT PF02450.10 KND87194.1 - 0.16 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PNP_UDP_1 PF01048.15 KND87195.1 - 0.00013 21.0 0.1 0.0007 18.6 0.0 1.8 1 1 1 2 2 2 1 Phosphorylase superfamily DUF3046 PF11248.3 KND87196.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Cerato-platanin PF07249.7 KND87197.1 - 8.8e-05 22.4 0.3 0.00017 21.6 0.2 1.5 1 0 0 1 1 1 1 Cerato-platanin CDC37_N PF03234.9 KND87201.1 - 9.5e-49 166.0 3.5 9.5e-49 166.0 2.4 2.1 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KND87201.1 - 5.6e-35 120.3 0.6 5.6e-35 120.3 0.4 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KND87201.1 - 1.7e-21 75.9 1.0 1.7e-21 75.9 0.7 2.9 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF2762 PF10960.3 KND87201.1 - 0.064 12.9 1.3 0.27 10.9 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) TBD PF12845.2 KND87201.1 - 0.098 12.2 2.7 1.2 8.7 0.1 2.7 2 0 0 2 2 2 0 TBD domain Ank_2 PF12796.2 KND87203.1 - 1.6e-95 313.6 10.6 5.9e-19 68.1 0.1 8.1 4 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KND87203.1 - 1.1e-85 277.3 20.9 6.2e-08 32.0 0.0 15.8 15 1 1 16 16 16 14 Ankyrin repeat Ank_3 PF13606.1 KND87203.1 - 4.9e-66 212.0 5.3 2.3e-05 24.2 0.0 15.1 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.1 KND87203.1 - 2.9e-65 214.8 13.1 2.5e-08 33.9 0.0 13.5 4 3 9 14 14 14 13 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND87203.1 - 2e-63 209.7 6.0 1.1e-10 41.7 0.0 11.2 6 3 8 14 14 14 12 Ankyrin repeats (many copies) WW PF00397.21 KND87203.1 - 9e-17 60.6 3.5 1.4e-07 31.2 0.1 2.4 2 0 0 2 2 2 2 WW domain NACHT PF05729.7 KND87203.1 - 1.7e-08 34.2 0.8 8.7e-08 31.9 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KND87203.1 - 0.00042 20.4 0.2 0.0034 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DHC_N1 PF08385.7 KND87203.1 - 0.019 13.3 0.3 0.58 8.4 0.0 2.4 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 NB-ARC PF00931.17 KND87203.1 - 0.047 12.5 0.0 0.092 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Ank_2 PF12796.2 KND87204.1 - 7.9e-26 90.2 0.1 8.3e-07 29.2 0.0 5.7 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND87204.1 - 9.9e-19 66.9 6.4 4.7e-07 29.8 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KND87204.1 - 1.2e-15 56.4 6.6 0.017 14.8 0.0 7.9 7 2 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KND87204.1 - 5e-14 52.3 1.5 0.00041 20.7 0.0 6.2 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87204.1 - 2.4e-10 39.6 0.1 0.58 10.5 0.0 7.3 7 0 0 7 7 7 2 Ankyrin repeat SNF2_N PF00176.18 KND87205.1 - 4.1e-30 104.5 0.5 4.9e-28 97.7 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KND87205.1 - 2e-11 43.5 0.0 4.9e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND87205.1 - 7.3e-08 32.4 0.2 2.5e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND87205.1 - 0.00029 20.3 0.1 0.016 14.7 0.0 3.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Gly-zipper_OmpA PF13436.1 KND87206.1 - 0.24 11.0 3.5 0.44 10.2 2.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain HET PF06985.6 KND87207.1 - 7.1e-24 84.5 0.1 1.2e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IPK PF03770.11 KND87208.1 - 1.5e-50 171.6 0.0 1.9e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 KND87209.1 - 9e-87 291.4 0.0 1.8e-86 290.4 0.0 1.5 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Pmp3 PF01679.12 KND87210.1 - 5.4e-19 67.6 8.2 7.1e-19 67.2 5.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator HA2 PF04408.18 KND87211.1 - 2.1e-27 95.1 0.3 2.1e-27 95.1 0.2 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KND87211.1 - 3.6e-27 94.4 0.0 2e-26 92.0 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 KND87211.1 - 8.2e-11 41.8 0.5 1.7e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 KND87211.1 - 2.3e-07 30.5 0.0 6.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND87211.1 - 8.2e-07 28.6 0.1 2.2e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND87211.1 - 4.8e-06 26.7 0.1 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KND87211.1 - 2.5e-05 23.3 0.6 0.00016 20.6 0.0 2.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.1 KND87211.1 - 0.0079 16.1 0.4 0.13 12.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND87211.1 - 0.0087 15.7 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Myosin_head PF00063.16 KND87211.1 - 0.058 11.4 0.0 0.091 10.7 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) ResIII PF04851.10 KND87211.1 - 0.061 13.1 0.6 2 8.2 0.1 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KND87211.1 - 0.07 12.3 0.3 0.26 10.4 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 KND87211.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KND87211.1 - 0.28 11.4 3.3 0.46 10.7 0.1 2.9 3 1 1 4 4 3 0 ABC transporter DUF1777 PF08648.7 KND87211.1 - 4.2 7.0 40.3 0.14 11.8 22.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) CVNH PF08881.5 KND87212.1 - 3.3e-26 91.5 0.1 4.2e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Ferric_reduct PF01794.14 KND87213.1 - 7.1e-20 71.3 13.3 2.1e-19 69.8 9.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KND87213.1 - 7.9e-10 38.5 0.0 9.6e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KND87213.1 - 1.1e-06 28.6 0.0 0.0021 17.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KND87213.1 - 0.19 12.3 0.0 0.78 10.3 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain SNF2_N PF00176.18 KND87214.1 - 6.2e-71 238.6 0.6 6.2e-71 238.6 0.4 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND87214.1 - 4.6e-17 61.6 0.1 1.1e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND87214.1 - 2.7e-08 33.8 0.2 8.8e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND87214.1 - 2.5e-05 23.8 0.0 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND87214.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KND87215.1 - 6.2e-62 205.9 30.6 2.5e-09 37.3 0.0 15.1 10 2 4 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 KND87215.1 - 9.1e-29 97.8 31.5 0.00055 19.6 0.0 21.6 24 3 0 24 24 24 7 Ankyrin repeat Ank_4 PF13637.1 KND87215.1 - 7.7e-24 83.6 20.5 0.015 15.8 0.0 16.1 18 1 1 19 19 19 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87215.1 - 7.8e-19 65.9 21.1 0.013 15.7 0.0 18.4 23 0 0 23 23 23 3 Ankyrin repeat Ank_5 PF13857.1 KND87215.1 - 4.7e-14 52.1 28.7 4.4e-07 29.9 0.0 15.6 17 2 2 19 19 19 2 Ankyrin repeats (many copies) Oligomerisation PF02410.10 KND87216.1 - 0.00094 19.1 0.0 0.023 14.7 0.0 2.6 3 0 0 3 3 3 1 Oligomerisation domain RNA_pol PF00940.14 KND87217.1 - 6.5e-161 535.3 0.0 1.1e-160 534.5 0.0 1.4 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KND87217.1 - 1.2e-76 258.0 2.0 2.1e-76 257.2 1.4 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF3420 PF11900.3 KND87217.1 - 0.027 14.5 0.2 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DHHA2 PF02833.9 KND87219.1 - 1.2e-22 80.4 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KND87219.1 - 4.8e-06 26.2 0.0 8.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 DHH family DEAD_assoc PF08494.6 KND87220.1 - 0.046 13.4 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 DEAD/H associated AAA_22 PF13401.1 KND87220.1 - 0.072 13.2 0.4 3.8 7.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain p450 PF00067.17 KND87224.1 - 5.1e-28 97.8 0.0 9.4e-20 70.5 0.0 2.2 1 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KND87225.1 - 3.6e-08 32.3 0.0 3.9e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 KND87226.1 - 1.6e-28 100.1 0.0 2e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND87226.1 - 1.9e-28 99.4 0.2 3.4e-28 98.6 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND87226.1 - 6.5e-08 32.4 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.10 KND87226.1 - 0.095 12.3 1.3 0.2 11.2 0.9 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MatE PF01554.13 KND87227.1 - 3.4e-50 169.8 23.2 4.3e-29 101.2 2.6 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KND87227.1 - 9.8e-05 22.1 8.2 9.8e-05 22.1 5.7 4.3 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.16 KND87228.1 - 4.1e-86 288.7 0.0 5e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KND87228.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Abhydrolase_6 PF12697.2 KND87231.1 - 1.5e-08 34.8 0.1 4.9e-08 33.1 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND87231.1 - 5.2e-05 23.0 0.0 0.00016 21.4 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KND87231.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.15 KND87231.1 - 0.0054 16.3 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Endosulfine PF04667.12 KND87232.1 - 2.3e-14 53.1 0.0 4.3e-14 52.2 0.0 1.5 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Pkinase PF00069.20 KND87235.1 - 1.1e-33 116.4 0.0 4.4e-33 114.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87235.1 - 1.1e-13 50.8 0.0 6.9e-07 28.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 KND87235.1 - 0.0055 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND87235.1 - 0.013 15.2 0.5 0.035 13.8 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KND87238.1 - 1.6e-45 155.3 0.0 2e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 KND87238.1 - 1.6e-22 79.5 0.1 4.9e-10 39.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 KND87238.1 - 3.4e-17 62.3 0.0 5.1e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.1 KND87238.1 - 6.6e-11 42.4 0.2 2.8e-06 27.6 0.0 4.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87238.1 - 2.7e-08 33.2 0.1 2.2 8.7 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.25 KND87238.1 - 7.5e-06 25.4 0.7 0.091 12.6 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 KND87238.1 - 0.0028 17.8 1.8 0.64 10.3 0.0 4.2 3 2 2 5 5 5 1 Ankyrin repeats (many copies) tRNA-synt_1g PF09334.6 KND87239.1 - 8.7e-134 446.0 0.0 1.4e-133 445.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KND87239.1 - 0.00094 18.9 0.2 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA YgbA_NO PF11756.3 KND87239.1 - 0.044 13.8 0.6 0.09 12.8 0.4 1.4 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter EamA PF00892.15 KND87241.1 - 0.019 14.9 3.0 0.019 14.9 2.1 3.0 3 0 0 3 3 3 0 EamA-like transporter family Keratin_matx PF04579.7 KND87241.1 - 0.031 14.5 0.7 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein ATP1G1_PLM_MAT8 PF02038.11 KND87241.1 - 0.06 12.3 1.4 9.8 5.2 0.1 2.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family zf-DHHC PF01529.15 KND87241.1 - 4.6 6.6 7.7 4.4 6.6 0.1 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase NAD_binding_4 PF07993.7 KND87243.1 - 1.6e-05 23.9 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KND87243.1 - 0.00016 21.7 0.0 0.00016 21.7 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND87243.1 - 0.00016 21.1 0.0 0.00016 21.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND87243.1 - 0.00032 19.5 0.0 0.00032 19.4 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KND87243.1 - 0.0008 19.3 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KND87243.1 - 0.014 14.6 0.0 0.015 14.5 0.0 1.0 1 0 0 1 1 1 0 NmrA-like family Ldh_1_N PF00056.18 KND87243.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KND87243.1 - 0.033 13.0 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Saccharop_dh PF03435.13 KND87243.1 - 0.054 12.4 0.0 0.054 12.4 0.0 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KND87243.1 - 0.059 12.2 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KND87243.1 - 0.12 12.7 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FMO-like PF00743.14 KND87244.1 - 1e-58 198.8 0.0 7e-56 189.5 0.0 3.1 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND87244.1 - 3.6e-27 95.7 0.0 1.1e-25 90.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND87244.1 - 1.1e-08 34.3 0.0 1.1e-06 27.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KND87244.1 - 4.6e-08 33.1 0.0 2.6e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND87244.1 - 6.2e-07 29.3 1.8 0.0012 18.5 0.0 3.9 4 1 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KND87244.1 - 5.3e-05 23.5 0.0 0.0038 17.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND87244.1 - 0.00014 21.8 0.1 0.00043 20.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain IlvN PF07991.7 KND87244.1 - 0.026 13.9 0.0 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 KND87244.1 - 0.033 14.2 0.0 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KND87244.1 - 0.07 12.9 0.5 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 KND87244.1 - 0.15 11.1 0.0 0.35 9.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.10 KND87244.1 - 0.18 11.5 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_72 PF03198.9 KND87245.1 - 9e-126 419.0 4.7 1.2e-125 418.6 3.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KND87245.1 - 1.2e-20 73.7 8.2 3.4e-20 72.3 5.7 1.8 1 0 0 1 1 1 1 X8 domain PAP2 PF01569.16 KND87245.1 - 1e-18 67.2 7.1 3.7e-18 65.4 4.9 2.0 1 0 0 1 1 1 1 PAP2 superfamily Glyco_hydro_2_C PF02836.12 KND87245.1 - 5.6e-07 28.7 0.1 1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 KND87246.1 - 2e-06 27.1 0.0 3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HSP70 PF00012.15 KND87248.1 - 7.9e-80 268.4 0.6 1.3e-79 267.7 0.4 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND87248.1 - 5e-08 31.9 0.1 1e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.1 KND87248.1 - 0.00015 21.2 0.7 0.00031 20.2 0.1 1.8 2 1 0 2 2 2 1 Periplasmic binding protein FtsA PF14450.1 KND87248.1 - 0.0057 16.4 2.3 0.34 10.7 0.0 3.0 3 1 0 3 3 3 2 Cell division protein FtsA BRAP2 PF07576.7 KND87248.1 - 0.085 12.4 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 BRCA1-associated protein 2 NB-ARC PF00931.17 KND87250.1 - 0.012 14.4 0.1 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KND87250.1 - 0.04 13.5 0.0 0.37 10.4 0.0 2.2 2 1 0 2 2 2 0 NACHT domain Pkinase PF00069.20 KND87254.1 - 1.7e-20 73.3 0.0 9.1e-20 70.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87254.1 - 6.8e-05 22.0 0.0 0.00031 19.9 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Ank_2 PF12796.2 KND87255.1 - 1.4e-23 83.0 0.1 5.1e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND87255.1 - 4.3e-20 70.4 1.1 2.7e-05 23.7 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KND87255.1 - 1.5e-17 63.5 0.0 8e-07 29.4 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87255.1 - 2.2e-12 45.9 0.1 0.025 14.7 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KND87255.1 - 3.4e-12 46.1 0.1 0.00012 22.1 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 KND87255.1 - 4.6e-10 39.4 0.0 8.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND87255.1 - 2.5e-08 34.1 1.5 3.3e-07 30.4 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND87255.1 - 3.4e-05 23.9 0.0 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KND87255.1 - 0.0024 16.7 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 KND87255.1 - 0.008 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF1843 PF08898.5 KND87255.1 - 0.013 15.4 0.3 2.4 8.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Arch_ATPase PF01637.13 KND87255.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KND87255.1 - 0.024 14.7 0.0 0.086 13.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KND87255.1 - 0.17 11.8 0.1 0.55 10.1 0.0 2.0 2 1 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 KND87255.1 - 0.22 10.4 0.0 0.68 8.8 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain GST_C PF00043.20 KND87256.1 - 0.00015 21.6 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND87256.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND87256.1 - 0.02 15.3 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NT-C2 PF10358.4 KND87257.1 - 2.4e-20 72.4 0.0 3.7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ABC_tran PF00005.22 KND87258.1 - 2.1e-45 154.3 0.0 4.6e-22 78.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND87258.1 - 7.1e-19 68.8 0.8 0.00014 21.9 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KND87258.1 - 7.2e-19 67.4 1.8 7.2e-19 67.4 1.3 2.4 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 KND87258.1 - 4.7e-11 42.3 0.5 0.0027 16.9 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND87258.1 - 4.9e-09 35.5 0.4 0.00089 18.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KND87258.1 - 6.3e-09 36.4 1.4 0.033 14.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KND87258.1 - 2.8e-07 31.3 0.0 0.0034 18.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KND87258.1 - 5.7e-06 26.6 0.0 0.036 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KND87258.1 - 9.6e-06 24.8 0.0 0.0043 16.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND87258.1 - 1e-05 25.6 0.0 0.15 12.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 KND87258.1 - 3.6e-05 24.2 0.0 0.095 13.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 KND87258.1 - 4.3e-05 23.7 0.0 0.35 11.0 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KND87258.1 - 9.5e-05 22.3 0.1 0.089 12.7 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KND87258.1 - 0.0001 22.3 0.4 0.24 11.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KND87258.1 - 0.00011 21.7 0.0 0.11 11.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KND87258.1 - 0.00011 21.9 0.2 0.52 9.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 KND87258.1 - 0.00024 20.9 0.1 0.31 10.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 KND87258.1 - 0.00027 20.9 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KND87258.1 - 0.00033 20.7 0.0 1.5 8.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_10 PF12846.2 KND87258.1 - 0.0006 19.3 0.7 0.43 9.9 0.2 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 KND87258.1 - 0.00086 19.0 0.2 0.95 9.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KND87258.1 - 0.0011 18.8 0.0 2 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 KND87258.1 - 0.0016 17.5 0.0 0.61 9.0 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 KND87258.1 - 0.0022 17.6 0.9 12 5.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.1 KND87258.1 - 0.0022 17.8 0.6 0.43 10.5 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KND87258.1 - 0.0023 17.7 0.1 2 8.2 0.0 3.0 3 0 0 3 3 3 1 Dynamin family Arch_ATPase PF01637.13 KND87258.1 - 0.0029 17.3 0.0 2.2 7.8 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase MobB PF03205.9 KND87258.1 - 0.0035 17.0 0.2 0.05 13.3 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 KND87258.1 - 0.014 14.3 0.4 2.7 6.8 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 KND87258.1 - 0.02 13.7 0.1 4.2 6.1 0.0 3.0 2 1 0 2 2 2 0 NB-ARC domain DUF2813 PF11398.3 KND87258.1 - 0.02 13.9 0.8 3.4 6.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) NTPase_1 PF03266.10 KND87258.1 - 0.063 12.9 0.2 4.4 6.9 0.1 2.5 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.20 KND87258.1 - 0.099 12.1 0.0 2.1 7.7 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 KND87258.1 - 0.15 11.3 0.4 8.5 5.6 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B APH PF01636.18 KND87262.1 - 4.5e-10 39.6 0.8 6.3e-10 39.1 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_1 PF00583.19 KND87265.1 - 5.6e-13 48.7 0.6 1.1e-12 47.7 0.4 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND87265.1 - 2.2e-12 46.9 0.0 1.6e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND87265.1 - 3.2e-10 40.1 0.2 6.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND87265.1 - 5.8e-06 26.1 0.0 4.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KND87265.1 - 9.4e-06 25.3 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KND87265.1 - 3.7e-05 23.5 0.1 0.00033 20.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND87265.1 - 0.012 15.5 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TrkH PF02386.11 KND87266.1 - 2.4e-91 305.9 6.6 3.5e-89 298.8 0.2 2.1 2 0 0 2 2 2 2 Cation transport protein SNF2_N PF00176.18 KND87267.1 - 5.5e-71 238.7 1.4 1.1e-70 237.7 1.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KND87267.1 - 6e-50 168.9 17.0 6e-50 168.9 11.8 4.6 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 KND87267.1 - 2.8e-16 59.1 0.0 8.5e-16 57.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain APH PF01636.18 KND87268.1 - 5.8e-06 26.2 0.4 1.1e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HNH_2 PF13391.1 KND87269.1 - 4e-15 55.3 0.0 1.4e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease DUF3435 PF11917.3 KND87270.1 - 1.5e-27 96.4 0.5 3.6e-26 91.8 0.4 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) PTCB-BRCT PF12738.2 KND87271.1 - 1.3e-10 40.9 0.1 2.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KND87271.1 - 3.2e-10 40.0 0.0 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KND87271.1 - 0.0012 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KND87271.1 - 0.007 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) SEN1_N PF12726.2 KND87274.1 - 6.2e-116 388.2 3.0 7.6e-116 387.9 2.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KND87274.1 - 1.3e-68 231.1 2.3 1.6e-68 230.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KND87274.1 - 7.8e-62 208.2 0.0 1.3e-61 207.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND87274.1 - 2e-09 37.0 1.3 2e-09 37.0 0.9 2.5 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KND87274.1 - 1.6e-06 27.8 3.0 0.00032 20.3 0.3 3.4 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 KND87274.1 - 5.2e-05 22.6 0.0 0.019 14.2 0.0 2.8 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KND87274.1 - 0.00018 21.1 0.2 0.19 11.1 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KND87274.1 - 0.067 13.3 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DNA_methylase PF00145.12 KND87275.1 - 1.2e-40 139.6 0.0 5.1e-28 98.1 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.10 KND87275.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_12 PF13087.1 KND87276.1 - 3.8e-23 81.9 0.0 5.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND87276.1 - 7e-12 45.4 0.0 2.3e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KND87276.1 - 6.5e-09 35.8 0.1 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KND87276.1 - 0.0004 19.9 0.0 0.034 13.6 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KND87276.1 - 0.078 12.5 0.0 18 4.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain HemY_N PF07219.8 KND87277.1 - 0.19 11.3 0.5 20 4.8 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Syndecan PF01034.15 KND87277.1 - 5.3 6.7 5.1 11 5.7 3.6 1.5 1 0 0 1 1 1 0 Syndecan domain Ank PF00023.25 KND87278.1 - 0.0016 18.1 0.1 0.2 11.5 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat zf-C2H2_4 PF13894.1 KND87283.1 - 0.0051 17.0 17.6 0.087 13.2 1.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger HypA PF01155.14 KND87283.1 - 0.32 10.7 1.2 0.83 9.3 0.8 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Aft1_HRR PF11787.3 KND87284.1 - 3.6 8.7 8.3 8.7 7.4 5.8 1.7 1 1 0 1 1 1 0 Aft1 HRR domain MSA-2c PF12238.3 KND87284.1 - 8.7 5.9 6.4 11 5.5 4.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c APH PF01636.18 KND87285.1 - 0.00013 21.7 1.4 0.00024 20.9 1.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family SUA5 PF03481.8 KND87285.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding Cmc1 PF08583.5 KND87286.1 - 2.6e-16 59.1 1.0 2.6e-16 59.1 0.7 1.9 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KND87286.1 - 0.016 15.0 0.8 3.2 7.7 0.2 2.4 2 0 0 2 2 2 0 CHCH domain FtsL PF04999.8 KND87286.1 - 0.12 12.1 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsL DUF3128 PF11326.3 KND87286.1 - 0.24 11.5 5.4 2.8 8.1 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) p450 PF00067.17 KND87287.1 - 2.7e-50 171.2 0.0 3.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 KND87288.1 - 9.5e-30 102.5 1.9 2.4e-29 101.2 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND87288.1 - 1.6e-23 82.7 0.2 2.8e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND87288.1 - 3.3e-07 31.2 0.3 7.7e-07 30.0 0.2 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KND87288.1 - 0.015 15.8 0.0 0.045 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox PF00070.22 KND87288.1 - 0.042 14.2 0.6 0.33 11.3 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 KND87288.1 - 0.053 13.3 1.8 0.33 10.7 0.5 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 KND87288.1 - 0.056 11.9 0.5 0.083 11.3 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Met_10 PF02475.11 KND87288.1 - 0.062 12.8 0.4 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Met-10+ like-protein MARVEL PF01284.18 KND87289.1 - 1.3e-08 34.7 17.8 2.4e-08 33.9 11.5 1.8 1 1 1 2 2 2 1 Membrane-associating domain DUF4212 PF13937.1 KND87289.1 - 2.9 7.9 7.9 0.3 11.1 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF3487 PF11990.3 KND87289.1 - 5.6 6.3 9.8 6.5 6.1 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) TRI5 PF06330.6 KND87290.1 - 2.4e-147 490.5 1.7 3.2e-147 490.0 1.2 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Methyltransf_25 PF13649.1 KND87291.1 - 9.8e-08 32.2 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87291.1 - 2e-07 31.4 0.0 3e-06 27.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND87291.1 - 6.4e-07 29.2 0.0 7.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87291.1 - 7.8e-07 29.4 0.0 3.5e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87291.1 - 1.1e-06 28.3 0.0 5.1e-06 26.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87291.1 - 3.8e-06 27.4 0.0 7.1e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND87291.1 - 0.00035 20.0 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KND87291.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KND87291.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 KND87291.1 - 0.0027 17.3 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KND87291.1 - 0.034 13.5 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW NUDIX PF00293.23 KND87295.1 - 4.4e-20 71.7 0.1 7.8e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_8 PF13523.1 KND87295.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 KND87297.1 - 3.4e-08 32.6 0.0 5.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87297.1 - 4.2e-08 32.9 7.2 1.1e-07 31.6 5.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KND87299.1 - 5.7e-16 58.9 0.2 8.4e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87299.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Atg14 PF10186.4 KND87300.1 - 6.3e-16 58.1 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 KND87301.1 - 1.1e-13 50.4 9.4 4.7e-06 26.2 0.3 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Spt20 PF12090.3 KND87301.1 - 0.099 11.9 3.2 0.18 11.1 2.2 1.3 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.7 KND87301.1 - 2.1 6.9 8.6 3.2 6.2 5.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.1 KND87301.1 - 5.5 4.5 20.8 8.4 3.9 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NACHT PF05729.7 KND87302.1 - 1.1e-14 54.3 0.0 3.1e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KND87302.1 - 0.00056 19.9 0.0 0.0025 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KND87302.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KND87302.1 - 0.05 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 KND87302.1 - 0.063 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KND87302.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PIF1 PF05970.9 KND87302.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.1 KND87302.1 - 0.1 12.7 0.0 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND87302.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Peptidase_S8 PF00082.17 KND87303.1 - 9.8e-16 57.7 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family APH PF01636.18 KND87304.1 - 3.2e-17 63.0 0.0 4.1e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND87304.1 - 0.0062 15.9 0.0 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KND87304.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KND87304.1 - 0.046 12.8 0.0 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase SBP_bac_3 PF00497.15 KND87304.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 IBR PF01485.16 KND87306.1 - 9.6e-13 47.8 28.4 2.3e-07 30.5 5.5 3.7 3 0 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 KND87306.1 - 0.00062 19.7 6.8 0.00062 19.7 4.7 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND87306.1 - 0.0019 17.9 8.7 0.0019 17.9 6.0 4.5 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND87306.1 - 0.0041 16.7 6.8 0.0041 16.7 4.7 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND87306.1 - 0.0064 16.1 6.9 0.0064 16.1 4.8 4.3 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND87306.1 - 0.019 14.8 6.6 0.019 14.8 4.6 3.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING APH PF01636.18 KND87308.1 - 0.0065 16.2 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_2 PF02230.11 KND87309.1 - 2.6e-29 102.2 0.0 1.2e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KND87309.1 - 3e-05 23.3 0.0 4.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND87309.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KND87309.1 - 0.029 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase ketoacyl-synt PF00109.21 KND87310.1 - 3.4e-72 242.9 1.6 1.1e-71 241.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KND87310.1 - 2.8e-61 206.3 1.9 3.2e-61 206.1 0.1 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KND87310.1 - 1e-57 195.6 0.4 2.3e-57 194.4 0.3 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KND87310.1 - 1.4e-46 158.5 0.1 7e-46 156.1 0.1 2.4 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND87310.1 - 2.8e-42 143.3 0.1 2.2e-41 140.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KND87310.1 - 1.3e-41 143.0 2.1 1.3e-37 129.9 1.9 2.8 2 1 0 3 3 3 2 Acyl transferase domain Methyltransf_12 PF08242.7 KND87310.1 - 5.6e-16 58.8 0.0 1.9e-15 57.1 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KND87310.1 - 7.1e-16 57.9 0.0 2.2e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND87310.1 - 5.2e-15 56.4 0.0 5e-14 53.2 0.0 2.8 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KND87310.1 - 2.2e-11 43.7 0.0 7.9e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87310.1 - 1.1e-06 28.2 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87310.1 - 1.2e-06 28.9 0.0 5.6e-06 26.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87310.1 - 1.5e-05 25.4 0.0 0.00013 22.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KND87310.1 - 0.00019 21.1 0.0 0.00048 19.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KND87310.1 - 0.008 16.4 0.6 0.025 14.8 0.4 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Saccharop_dh PF03435.13 KND87310.1 - 0.043 12.7 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase Methyltransf_16 PF10294.4 KND87310.1 - 0.17 11.2 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KND87310.1 - 0.38 9.8 0.0 0.73 8.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NAS PF03059.11 KND87310.1 - 0.48 9.5 0.0 0.93 8.5 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein APH PF01636.18 KND87311.1 - 2.2e-08 34.1 0.2 2.4e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87311.1 - 3.1e-07 30.1 0.0 4.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KND87311.1 - 0.0047 16.1 0.0 0.0054 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AAA_12 PF13087.1 KND87314.1 - 4.8e-40 137.0 0.1 1.2e-39 135.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND87314.1 - 4e-28 98.5 0.0 4e-28 98.5 0.0 4.3 4 1 0 4 4 4 1 AAA domain AAA PF00004.24 KND87314.1 - 3.4e-18 66.1 0.0 3.5e-06 27.2 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KND87314.1 - 9e-12 44.5 1.1 1.8e-06 27.6 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 KND87314.1 - 9e-10 38.4 0.6 0.025 14.1 0.0 4.3 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.1 KND87314.1 - 1.6e-08 34.7 0.8 0.017 15.2 0.0 5.3 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KND87314.1 - 6.5e-06 26.9 4.8 0.057 14.2 0.1 4.7 4 1 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KND87314.1 - 0.00016 21.9 1.0 1.3 9.3 0.1 4.5 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 KND87314.1 - 0.00065 19.4 0.1 1.3 8.6 0.1 3.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KND87314.1 - 0.0014 17.8 2.5 0.92 8.6 0.0 3.3 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND87314.1 - 0.0064 15.9 0.1 5 6.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 KND87314.1 - 0.021 14.9 0.0 7.5 6.7 0.0 3.1 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 KND87314.1 - 0.029 13.8 0.0 12 5.3 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 KND87314.1 - 0.034 14.0 0.2 1.2 8.9 0.1 3.1 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 KND87314.1 - 0.038 13.6 0.3 3.8 7.1 0.0 3.5 3 0 0 3 3 3 0 Helicase DUF4407 PF14362.1 KND87314.1 - 0.21 10.5 6.7 0.47 9.3 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2514 PF10721.4 KND87315.1 - 0.039 13.6 3.1 0.053 13.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4019 PF13211.1 KND87315.1 - 0.089 13.0 0.4 0.13 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) Fungal_trans PF04082.13 KND87318.1 - 1.6e-32 112.4 2.6 1.9e-32 112.1 1.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87318.1 - 2.7e-07 30.3 9.5 5.1e-07 29.4 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KND87318.1 - 8.8e-05 22.3 0.3 0.0002 21.2 0.2 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain APH PF01636.18 KND87319.1 - 0.00073 19.3 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KND87319.1 - 0.047 12.6 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase NARP1 PF12569.3 KND87320.1 - 7.6 5.1 11.1 12 4.5 7.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAF-AH_p_II PF03403.8 KND87321.1 - 7.7e-46 156.0 0.0 1.3e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KND87321.1 - 4.1e-09 36.3 0.1 5.7e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND87321.1 - 1.9e-06 27.9 0.0 5.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KND87321.1 - 2.3e-05 23.4 0.0 0.00024 20.0 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KND87321.1 - 3e-05 22.9 0.0 0.00021 20.1 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KND87321.1 - 0.024 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ribosomal_S30 PF04758.9 KND87322.1 - 1.3e-27 95.2 4.8 2e-27 94.6 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 RRM_1 PF00076.17 KND87323.1 - 1.6e-14 53.3 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND87323.1 - 9.2e-12 44.7 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND87323.1 - 4e-09 36.1 0.0 5.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 KND87324.1 - 1.6e-06 28.0 0.8 2.6e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87324.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase PhyH PF05721.8 KND87325.1 - 1.3e-27 97.2 0.0 1.6e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3626 PF12294.3 KND87325.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Fungal_trans_2 PF11951.3 KND87326.1 - 1.2e-07 30.6 0.0 1.2e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KND87327.1 - 6.9e-15 54.5 0.1 8e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87327.1 - 1.2e-06 28.3 4.8 1.9e-06 27.6 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 KND87327.1 - 0.88 9.7 4.9 1.9 8.6 3.4 1.5 1 0 0 1 1 1 0 Opy2 protein zf-B_box PF00643.19 KND87328.1 - 0.0098 15.7 1.6 0.018 14.8 1.1 1.4 1 0 0 1 1 1 1 B-box zinc finger LMBR1 PF04791.11 KND87329.1 - 6.7e-16 57.9 13.0 3.5e-13 48.9 9.0 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF4149 PF13664.1 KND87329.1 - 0.019 15.0 2.6 0.019 15.0 1.8 4.7 4 2 0 4 4 4 0 Domain of unknown function (DUF4149) Pal1 PF08316.6 KND87330.1 - 2.4e-07 31.3 0.8 1.9e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 Pal1 cell morphology protein Mucin PF01456.12 KND87330.1 - 0.087 12.5 8.6 0.23 11.2 6.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 KND87330.1 - 0.13 10.0 1.2 0.17 9.5 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.4 KND87330.1 - 0.72 8.0 16.9 0.96 7.6 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HVSL PF09749.4 KND87331.1 - 2.9e-65 219.6 0.0 3.4e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein NACHT PF05729.7 KND87332.1 - 8.9e-09 35.2 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND87332.1 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KND87332.1 - 0.00018 20.5 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PIF1 PF05970.9 KND87332.1 - 0.0053 15.7 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 PIF1-like helicase AAA_22 PF13401.1 KND87332.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KND87332.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KND87332.1 - 0.078 13.7 0.2 0.35 11.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KND87332.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KND87332.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPSF_A PF03178.10 KND87333.1 - 2.3e-67 227.3 0.0 1.5e-66 224.7 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region BNIP2 PF12496.3 KND87333.1 - 0.097 12.8 0.3 0.32 11.1 0.2 1.9 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ERO1 PF04137.10 KND87334.1 - 9.8e-135 449.1 0.0 1.2e-134 448.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pkinase PF00069.20 KND87337.1 - 9.4e-46 156.0 0.0 1.4e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87337.1 - 7.2e-21 74.4 0.0 1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND87337.1 - 8.9e-08 31.4 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Trp_halogenase PF04820.9 KND87338.1 - 1.7e-26 92.8 0.0 2.6e-12 46.1 0.1 2.6 1 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KND87338.1 - 6.9e-12 45.0 0.0 2e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND87338.1 - 5.3e-07 28.8 0.1 1.3e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND87338.1 - 4.4e-06 26.6 0.2 2.5e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND87338.1 - 2.2e-05 24.4 0.0 3.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND87338.1 - 0.00045 19.4 0.1 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND87338.1 - 0.0008 17.9 0.0 0.0012 17.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KND87338.1 - 0.0009 18.1 0.1 0.0016 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KND87338.1 - 0.0031 16.4 0.1 0.0046 15.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KND87338.1 - 0.0066 15.5 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KND87338.1 - 0.0069 16.7 0.1 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND87338.1 - 0.0088 16.1 0.0 0.028 14.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KND87338.1 - 0.018 14.8 0.1 0.088 12.6 0.1 2.0 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 KND87338.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KND87338.1 - 0.061 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KND87338.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 KND87339.1 - 9.8e-66 221.8 1.1 1.8e-65 220.9 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND87339.1 - 1.1e-32 113.6 3.3 1.5e-32 113.1 0.8 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KND87339.1 - 4.7e-28 97.4 0.0 1.1e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KND87339.1 - 1.9e-12 47.2 0.6 6.2e-12 45.6 0.2 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KND87339.1 - 8.8e-12 45.3 0.0 2.5e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87339.1 - 2.8e-08 33.5 0.0 5.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND87339.1 - 4.4e-08 32.9 0.0 1.7e-07 31.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87339.1 - 3e-07 30.9 0.0 2.3e-06 28.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87339.1 - 4.3e-07 30.3 0.0 1.6e-06 28.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND87339.1 - 9.2e-05 22.7 0.0 0.00042 20.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KND87339.1 - 0.00051 19.1 1.4 0.00073 18.5 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KND87339.1 - 0.0054 16.7 0.0 0.043 13.8 0.0 2.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KND87339.1 - 0.028 13.8 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FAD_binding_3 PF01494.14 KND87340.1 - 1.7e-23 83.2 0.1 4.4e-23 81.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND87340.1 - 1.1e-06 27.7 5.2 1.3e-05 24.3 2.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 KND87340.1 - 0.00093 18.0 0.0 0.062 12.1 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 KND87340.1 - 0.0022 18.3 2.6 0.0032 17.8 0.9 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KND87340.1 - 0.013 15.1 0.5 0.02 14.5 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain M20_dimer PF07687.9 KND87340.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 Peptidase dimerisation domain HI0933_like PF03486.9 KND87340.1 - 0.068 11.6 0.8 0.099 11.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 KND87340.1 - 0.083 12.9 1.2 0.25 11.3 0.9 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KND87340.1 - 0.085 11.9 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KND87340.1 - 0.091 12.1 1.0 0.14 11.5 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KND87340.1 - 0.12 12.4 0.9 0.64 10.0 0.6 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND87340.1 - 0.17 10.7 2.0 0.67 8.7 0.8 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KND87340.1 - 0.32 10.8 2.1 0.61 9.9 1.4 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND87340.1 - 0.65 9.7 2.5 15 5.3 1.7 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 KND87341.1 - 1.6e-30 106.0 51.2 6e-27 94.2 35.5 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2613 PF11021.3 KND87341.1 - 0.00071 19.2 0.0 0.008 15.8 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2613) adh_short PF00106.20 KND87342.1 - 0.0008 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 KND87343.1 - 1.5e-17 63.3 0.1 2.9e-17 62.3 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87343.1 - 3.4e-09 36.4 10.0 5.8e-09 35.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 KND87344.1 - 1.7e-12 47.9 0.0 2.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 SET domain RdRP PF05183.7 KND87345.1 - 7.6e-179 596.1 0.0 1e-178 595.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 KND87345.1 - 0.00031 20.6 0.0 0.5 10.3 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND87345.1 - 0.00039 19.9 0.0 0.016 14.8 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.7 KND87346.1 - 1.5e-27 96.5 13.7 2e-27 96.1 9.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family 2TM PF13239.1 KND87346.1 - 0.29 11.2 1.2 0.72 9.9 0.8 1.7 1 1 0 1 1 1 0 2TM domain CobD_Cbib PF03186.8 KND87346.1 - 0.64 9.0 3.8 0.41 9.6 1.2 1.7 2 0 0 2 2 2 0 CobD/Cbib protein Pox_P21 PF05313.7 KND87346.1 - 1.1 8.4 4.5 2.2 7.4 3.1 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF4231 PF14015.1 KND87346.1 - 1.7 8.6 5.7 0.26 11.2 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2207 PF09972.4 KND87346.1 - 2.7 6.4 3.8 4.5 5.7 2.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC1 PF03109.11 KND87347.1 - 9.7e-22 77.1 0.0 4.2e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 KND87351.1 - 5.5e-07 28.9 0.0 7.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND87351.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND87351.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family TspO_MBR PF03073.10 KND87352.1 - 0.13 11.8 4.6 0.15 11.5 3.2 1.1 1 0 0 1 1 1 0 TspO/MBR family Kelch_4 PF13418.1 KND87354.1 - 1.6e-34 117.4 7.9 2.1e-06 27.3 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KND87354.1 - 2.4e-33 113.5 6.0 3.8e-08 33.1 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KND87354.1 - 2.4e-30 103.9 11.2 1.6e-07 31.2 0.1 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KND87354.1 - 5.3e-26 89.9 3.9 2.7e-08 33.2 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KND87354.1 - 6.3e-26 89.4 5.0 2.8e-09 36.7 0.3 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KND87354.1 - 5.6e-18 63.9 6.4 2.2e-06 27.1 0.1 6.3 6 0 0 6 6 6 4 Kelch motif ADIP PF11559.3 KND87354.1 - 0.0042 17.0 3.6 0.0042 17.0 2.5 6.9 3 2 3 7 7 7 2 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KND87354.1 - 0.054 13.8 0.4 0.054 13.8 0.2 7.0 6 1 1 7 7 7 0 Protein of unknown function (DUF904) zf-C2H2 PF00096.21 KND87355.1 - 3.4e-10 39.6 14.4 3.8e-05 23.7 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND87355.1 - 6.6e-10 38.7 5.1 3.2e-06 27.1 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND87355.1 - 1.6e-08 34.2 9.2 5.8e-05 23.1 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger BolA PF01722.13 KND87355.1 - 0.0031 17.4 0.8 0.91 9.5 0.0 2.4 1 1 1 2 2 2 2 BolA-like protein zf-C2HC_2 PF13913.1 KND87355.1 - 0.059 13.0 2.0 0.15 11.7 1.4 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KND87355.1 - 0.16 12.1 3.9 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KND87355.1 - 0.22 11.3 5.1 0.25 11.1 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 KND87355.1 - 0.22 11.7 8.9 0.19 11.9 2.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Hepcidin PF06446.7 KND87355.1 - 0.37 11.2 2.4 0.93 9.9 1.7 1.6 1 0 0 1 1 1 0 Hepcidin zf-C2H2_6 PF13912.1 KND87355.1 - 0.57 10.1 7.0 8.3 6.4 0.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Bd3614-deam PF14439.1 KND87355.1 - 3.3 7.5 6.1 7.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase SRF-TF PF00319.13 KND87357.1 - 7.7e-23 79.4 0.5 1e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 KND87357.1 - 0.0048 16.2 0.1 0.0067 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) CDC45 PF02724.9 KND87357.1 - 0.19 9.6 0.1 0.25 9.3 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Raptor_N PF14538.1 KND87359.1 - 5e-63 211.5 0.0 9.8e-63 210.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KND87359.1 - 1e-08 34.7 1.1 0.34 10.8 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KND87359.1 - 9.3e-06 25.3 0.1 0.02 14.6 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 KND87359.1 - 0.00084 19.5 0.5 0.31 11.3 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats Atx10homo_assoc PF09759.4 KND87359.1 - 0.0013 18.4 0.2 0.0026 17.4 0.1 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 KND87359.1 - 0.064 13.3 6.3 0.67 10.1 0.1 4.9 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.2 KND87359.1 - 0.15 11.9 0.6 14 5.4 0.0 3.0 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SMC_N PF02463.14 KND87361.1 - 1.3e-26 93.2 0.2 1.8e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND87361.1 - 2.3e-14 54.1 16.8 2.3e-14 54.1 11.7 4.7 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KND87361.1 - 6e-08 32.9 0.3 7e-05 22.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KND87361.1 - 0.0057 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KND87361.1 - 0.026 13.7 0.1 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Baculo_PEP_C PF04513.7 KND87361.1 - 0.27 11.0 7.1 28 4.5 0.4 4.8 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 KND87361.1 - 0.33 11.1 0.1 0.33 11.1 0.0 5.8 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.20 KND87362.1 - 1.4e-71 240.7 0.0 2.6e-71 239.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87362.1 - 3.3e-34 118.1 0.0 2.2e-33 115.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KND87362.1 - 6.8e-06 25.2 0.0 2.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Malate_synthase PF01274.17 KND87363.1 - 1.6e-230 765.6 0.0 1.8e-230 765.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Spc7 PF08317.6 KND87365.1 - 0.00049 18.8 7.9 0.0017 17.1 0.3 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein BLOC1_2 PF10046.4 KND87365.1 - 0.0014 18.7 3.0 0.0014 18.7 2.0 2.5 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_tail_1 PF01576.14 KND87365.1 - 0.0083 13.9 17.6 0.05 11.3 3.1 2.2 2 0 0 2 2 2 2 Myosin tail GvpK PF05121.7 KND87365.1 - 0.015 15.0 2.1 0.015 15.0 1.4 2.6 3 1 0 3 3 2 0 Gas vesicle protein K Filament PF00038.16 KND87365.1 - 0.018 14.5 14.9 0.24 10.8 3.1 2.5 3 0 0 3 3 3 0 Intermediate filament protein GAS PF13851.1 KND87365.1 - 0.02 14.0 16.3 0.18 11.0 2.7 2.5 3 0 0 3 3 2 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 KND87365.1 - 0.062 12.6 5.4 0.76 9.1 0.4 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.3 KND87365.1 - 0.074 12.9 16.8 0.06 13.2 2.5 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KND87365.1 - 0.1 12.2 20.5 0.061 12.9 3.8 2.4 3 0 0 3 3 3 0 IncA protein DUF972 PF06156.8 KND87365.1 - 0.11 12.8 14.6 0.25 11.7 2.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) ATG16 PF08614.6 KND87365.1 - 0.14 11.9 16.3 0.14 11.9 2.0 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 KND87365.1 - 0.22 10.5 12.5 0.36 9.8 1.1 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 IL6 PF00489.12 KND87365.1 - 0.26 10.8 7.5 0.33 10.5 0.5 2.5 3 0 0 3 3 3 0 Interleukin-6/G-CSF/MGF family NPV_P10 PF05531.7 KND87365.1 - 0.33 11.2 3.0 0.32 11.2 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 KND87365.1 - 0.35 10.8 6.2 0.47 10.3 0.2 3.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Cluap1 PF10234.4 KND87365.1 - 0.48 9.5 10.8 1.8 7.7 1.4 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 GrpE PF01025.14 KND87365.1 - 0.63 9.5 16.6 0.27 10.7 3.7 2.5 2 0 0 2 2 2 0 GrpE BBP1_C PF15272.1 KND87365.1 - 0.68 9.4 7.8 0.86 9.1 1.0 2.5 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Spc24 PF08286.6 KND87365.1 - 0.82 9.3 14.7 0.59 9.8 2.5 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Laminin_II PF06009.7 KND87365.1 - 1 9.1 12.9 1.2 8.9 0.5 2.8 3 0 0 3 3 3 0 Laminin Domain II Lge1 PF11488.3 KND87365.1 - 1.5 9.0 7.4 9.9 6.4 0.5 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 TBPIP PF07106.8 KND87365.1 - 2.6 7.5 15.1 3.4 7.1 0.9 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 KND87365.1 - 3.1 7.5 20.6 1.3 8.8 1.9 3.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KND87365.1 - 7 4.9 11.6 37 2.5 8.0 1.9 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KND87365.1 - 7.4 6.4 23.7 0.37 10.6 4.4 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 KND87365.1 - 8.2 6.3 10.5 3.6 7.4 0.9 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Aldedh PF00171.17 KND87366.1 - 1.6e-118 396.0 0.2 1.9e-118 395.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.24 KND87367.1 - 7.7e-42 142.6 0.0 8.6e-41 139.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND87367.1 - 1.3e-22 79.4 1.9 5.9e-22 77.3 0.1 2.8 3 1 1 4 4 4 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KND87367.1 - 0.0083 14.5 0.1 2 6.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 KND87367.1 - 0.01 14.9 0.4 0.021 13.9 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 KND87367.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 KND87367.1 - 0.18 11.6 0.0 0.46 10.2 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HAD PF12710.2 KND87368.1 - 7.3e-13 49.1 0.1 2e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KND87368.1 - 2.6e-12 46.2 0.2 9.3e-12 44.4 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KND87368.1 - 8.5e-12 44.8 0.1 7.5e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KND87368.1 - 2.3e-10 41.2 2.8 5.4e-08 33.5 1.9 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND87368.1 - 0.012 15.2 0.4 0.031 13.8 0.3 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1895 PF08988.5 KND87368.1 - 0.092 12.7 0.8 0.24 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Treslin_N PF15292.1 KND87370.1 - 0.032 12.1 0.0 0.036 11.9 0.0 1.2 1 0 0 1 1 1 0 Treslin N-terminus vATP-synt_E PF01991.13 KND87371.1 - 4e-64 215.5 10.0 4.7e-64 215.3 7.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ubiq_cyt_C_chap PF03981.7 KND87371.1 - 0.064 13.0 0.2 0.21 11.4 0.0 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone AAA_15 PF13175.1 KND87371.1 - 0.18 10.8 8.3 0.23 10.4 5.7 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF4045 PF13254.1 KND87371.1 - 0.92 8.7 6.3 1.1 8.4 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Gluconate_2-dh3 PF13618.1 KND87371.1 - 1.4 9.0 4.8 2.8 8.0 2.0 2.4 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 HK97-gp10_like PF04883.7 KND87371.1 - 2.6 9.0 5.4 8.7 7.3 0.8 3.0 2 2 1 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Thg1C PF14413.1 KND87371.1 - 9.4 5.9 8.0 2.4 7.8 3.0 1.8 1 1 0 2 2 2 0 Thg1 C terminal domain Mg_trans_NIPA PF05653.9 KND87372.1 - 1.3e-16 60.4 9.0 2e-16 59.8 6.2 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KND87372.1 - 5.9e-06 26.3 17.0 0.00019 21.4 0.0 3.1 3 0 0 3 3 3 2 EamA-like transporter family Tetraspannin PF00335.15 KND87373.1 - 4.9e-05 22.7 6.6 6.5e-05 22.3 4.6 1.1 1 0 0 1 1 1 1 Tetraspanin family ATG22 PF11700.3 KND87373.1 - 0.0018 16.8 1.2 0.0027 16.2 0.8 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4131 PF13567.1 KND87373.1 - 0.27 10.6 3.5 0.54 9.6 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cation_ATPase_C PF00689.16 KND87373.1 - 0.62 9.5 6.0 4.9 6.6 4.1 2.2 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Ribosomal_L24e PF01246.15 KND87374.1 - 1.1e-30 105.2 0.4 1.1e-30 105.2 0.3 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.5 KND87375.1 - 8.1e-33 113.0 0.1 1.1e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KND87375.1 - 2.6e-08 33.5 0.0 4.3e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family CBP4 PF07960.6 KND87376.1 - 3.9e-27 94.3 1.1 3.9e-27 94.3 0.8 1.8 2 0 0 2 2 2 1 CBP4 ERCC4 PF02732.10 KND87376.1 - 0.066 12.9 0.5 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 ERCC4 domain Stathmin PF00836.14 KND87376.1 - 0.089 12.4 5.6 0.17 11.5 3.9 1.4 1 0 0 1 1 1 0 Stathmin family NOZZLE PF08744.5 KND87376.1 - 0.093 12.0 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Plant transcription factor NOZZLE OPT PF03169.10 KND87377.1 - 3.2e-164 547.8 52.1 3.7e-164 547.5 36.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein tRNA-synt_2 PF00152.15 KND87378.1 - 3.1e-67 226.7 0.0 4.4e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND87378.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.3 KND87378.1 - 0.55 8.9 6.1 0.8 8.3 4.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 bZIP_1 PF00170.16 KND87379.1 - 8e-07 28.9 12.7 1.3e-06 28.2 8.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KND87379.1 - 0.0002 21.6 4.0 0.00038 20.7 2.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor LMSTEN PF07988.7 KND87379.1 - 0.021 14.0 2.9 1.7 7.9 0.2 2.6 2 0 0 2 2 2 0 LMSTEN motif NAM-associated PF14303.1 KND87379.1 - 0.025 14.8 1.7 0.041 14.1 1.2 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain bZIP_2 PF07716.10 KND87379.1 - 0.5 10.2 14.0 0.41 10.4 7.2 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Mak16 PF04874.9 KND87380.1 - 4.2 7.5 0.0 4.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Mak16 protein C-terminal region Septin PF00735.13 KND87381.1 - 6.3e-33 113.9 0.1 9.7e-12 44.4 0.0 3.1 3 0 0 3 3 3 3 Septin Dynamin_N PF00350.18 KND87381.1 - 0.002 17.9 0.0 0.014 15.2 0.0 2.3 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 KND87381.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KND87381.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family UPF0139 PF03669.8 KND87383.1 - 9.8e-08 31.4 0.1 1.2e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) GRP PF07172.6 KND87384.1 - 0.02 15.3 8.5 0.02 15.3 5.9 4.3 2 1 1 3 3 3 0 Glycine rich protein family S1-P1_nuclease PF02265.11 KND87385.1 - 2.8e-68 230.2 0.1 3.2e-68 230.1 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.9 KND87386.1 - 4.4e-37 125.4 8.7 2.9e-19 68.3 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat zf-RING_2 PF13639.1 KND87389.1 - 1.6e-13 50.2 5.4 2.5e-13 49.5 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KND87389.1 - 6.3e-11 41.8 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KND87389.1 - 2.2e-09 37.2 4.9 3.5e-09 36.5 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND87389.1 - 5.7e-09 35.9 2.0 1.2e-08 34.9 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KND87389.1 - 6.8e-09 35.2 2.7 1.1e-08 34.6 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND87389.1 - 5e-08 32.4 2.9 7.6e-08 31.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND87389.1 - 3e-07 30.0 2.2 4.7e-07 29.4 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KND87389.1 - 0.0011 18.7 0.9 0.002 17.9 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KND87389.1 - 0.055 13.2 2.3 0.12 12.1 1.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KND87389.1 - 0.061 13.1 3.0 0.15 11.9 2.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KND87389.1 - 0.071 13.0 2.2 0.19 11.6 1.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KND87389.1 - 0.094 12.7 3.3 0.17 11.9 2.3 1.4 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 KND87389.1 - 0.32 10.8 0.1 0.72 9.6 0.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 KND87389.1 - 0.49 10.0 2.6 0.97 9.0 1.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KND87389.1 - 0.67 10.0 3.4 1.2 9.1 2.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 KND87389.1 - 0.75 9.3 2.2 1.4 8.5 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KND87389.1 - 1.2 8.9 2.6 2 8.1 1.8 1.4 1 0 0 1 1 1 0 PHD-finger DUF3129 PF11327.3 KND87390.1 - 4.9e-20 72.1 10.3 1.9e-16 60.3 0.6 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3129) Ribosomal_S4e PF00900.15 KND87391.1 - 7.9e-31 105.5 0.4 1.6e-30 104.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KND87391.1 - 5.6e-16 58.1 2.9 1.6e-15 56.6 2.0 1.9 1 0 0 1 1 1 1 RS4NT (NUC023) domain Myb_DNA-binding PF00249.26 KND87391.1 - 8.9e-11 41.6 0.3 9.6e-07 28.7 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND87391.1 - 3.2e-10 39.9 0.0 0.00035 20.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain S4 PF01479.20 KND87391.1 - 0.00022 20.5 0.0 0.00042 19.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KND87391.1 - 1.5 8.6 4.4 1.2 8.9 1.4 2.3 2 0 0 2 2 2 0 KOW motif EI24 PF07264.6 KND87392.1 - 2.9e-06 26.8 8.4 7.2e-06 25.5 5.9 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LANC_like PF05147.8 KND87393.1 - 6.1e-11 41.4 0.0 1.6e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein LpxK PF02606.9 KND87393.1 - 0.034 13.0 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Zn_clus PF00172.13 KND87394.1 - 1.4e-07 31.2 12.2 2.3e-07 30.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID_30kDa PF03540.8 KND87394.1 - 0.078 12.8 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit HypA PF01155.14 KND87394.1 - 0.33 10.6 2.3 0.55 9.9 1.6 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Robl_LC7 PF03259.12 KND87395.1 - 3.8e-10 39.2 0.2 1e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 KND87396.1 - 3.1e-21 75.2 0.0 1.4e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation L_biotic_typeA PF04604.8 KND87396.1 - 0.085 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Type-A lantibiotic EOS1 PF12326.3 KND87397.1 - 2.3e-24 85.7 8.4 1.1e-20 73.8 1.7 2.2 1 1 1 2 2 2 2 N-glycosylation protein PEPcase PF00311.12 KND87397.1 - 0.27 9.0 0.8 0.88 7.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase SUI1 PF01253.17 KND87398.1 - 4.6e-29 100.0 5.3 5.6e-29 99.7 3.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KND87398.1 - 0.1 12.7 0.3 0.19 11.7 0.1 1.5 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DUF520 PF04461.8 KND87398.1 - 0.1 12.4 1.6 0.13 12.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) UPF0016 PF01169.14 KND87399.1 - 2.4e-42 142.9 25.1 5.5e-22 77.6 5.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF805 PF05656.9 KND87399.1 - 9.6 6.0 7.3 0.58 9.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) WD40 PF00400.27 KND87400.1 - 4.5e-23 80.2 21.1 2.2e-08 33.6 1.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KND87400.1 - 0.0023 16.3 2.5 0.18 10.0 0.0 3.4 4 0 0 4 4 4 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KND87400.1 - 0.043 12.5 0.7 6 5.4 0.3 2.9 2 1 0 2 2 2 0 Nup133 N terminal like Med12-LCEWAV PF12145.3 KND87400.1 - 0.3 9.5 3.2 0.45 8.9 2.2 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Beta-lactamase PF00144.19 KND87401.1 - 2.7e-13 49.6 0.2 2.5e-08 33.3 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase RRM_6 PF14259.1 KND87402.1 - 4.9e-08 32.8 0.0 7.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND87402.1 - 1.9e-05 24.2 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND87402.1 - 0.0045 16.8 0.1 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AdoMet_MTase PF07757.8 KND87403.1 - 1.9e-39 134.2 0.0 3e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KND87403.1 - 0.0021 17.7 0.0 0.0051 16.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KND87403.1 - 0.013 15.1 0.1 0.35 10.5 0.2 2.6 2 1 0 2 2 2 0 Methyltransferase domain ELK PF03789.8 KND87403.1 - 0.045 13.5 0.2 9.6 6.1 0.1 2.4 2 0 0 2 2 2 0 ELK domain Methyltransf_18 PF12847.2 KND87403.1 - 0.075 13.6 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Herpes_UL95 PF03038.9 KND87404.1 - 2.8 6.7 3.5 5.7 5.7 2.4 1.4 1 0 0 1 1 1 0 UL95 family ATP-sulfurylase PF01747.12 KND87405.1 - 1.5e-89 299.0 0.2 2.1e-89 298.4 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KND87405.1 - 1.2e-56 190.7 0.0 2e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KND87405.1 - 2.7e-50 169.8 0.0 4.3e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 KND87405.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TRP PF06011.7 KND87406.1 - 2.2e-93 313.2 16.8 3.5e-93 312.5 11.6 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND87406.1 - 2.1e-29 102.3 0.0 3.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain NAC PF01849.13 KND87407.1 - 1.1e-12 47.2 0.4 2.4e-12 46.2 0.3 1.6 1 0 0 1 1 1 1 NAC domain Borealin PF10512.4 KND87407.1 - 0.085 12.7 0.1 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Cell division cycle-associated protein 8 Shadoo PF14999.1 KND87407.1 - 5.4 6.8 5.4 0.8 9.5 1.0 1.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective A_deamin PF02137.13 KND87408.1 - 2.6e-49 168.3 0.0 6.4e-33 114.5 0.0 2.0 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain NACHT PF05729.7 KND87409.1 - 1.7e-08 34.2 0.1 3e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND87409.1 - 4.5e-07 30.0 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND87409.1 - 0.0029 17.7 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KND87409.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 KND87409.1 - 0.041 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KND87409.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KND87409.1 - 0.1 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KND87409.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KND87409.1 - 0.15 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CoA_binding PF02629.14 KND87411.1 - 1.3e-27 96.1 3.8 1e-26 93.2 0.2 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KND87411.1 - 1.2e-24 86.6 0.9 1.9e-24 86.0 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KND87411.1 - 3.5e-09 36.3 0.1 6.2e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KND87411.1 - 0.0029 17.7 0.2 0.0098 16.0 0.0 2.0 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 KND87411.1 - 0.12 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UQ_con PF00179.21 KND87412.1 - 1.2e-33 115.4 0.0 1.6e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KND87412.1 - 1.4e-07 30.9 0.2 2.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KND87412.1 - 0.0055 16.4 0.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic E2 family B UEV PF05743.8 KND87412.1 - 0.071 12.7 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UEV domain HET PF06985.6 KND87413.1 - 1.1e-31 109.8 0.1 1.8e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KND87414.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DUF4281 PF14108.1 KND87414.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) DUF500 PF04366.7 KND87415.1 - 8.7e-37 125.3 0.0 2.1e-36 124.1 0.0 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) Radical_SAM PF04055.16 KND87416.1 - 1.7e-15 57.5 0.1 6.1e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KND87416.1 - 1.8e-11 43.8 0.1 5.2e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND87416.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_28 PF00295.12 KND87417.1 - 7.4e-32 110.5 0.6 1.2e-31 109.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KND87417.1 - 0.46 10.2 12.4 0.31 10.7 5.5 2.5 1 1 1 2 2 2 0 Right handed beta helix region MUG113 PF13455.1 KND87418.1 - 1.1e-28 99.5 0.2 3.5e-28 97.8 0.1 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KND87418.1 - 6.1e-20 71.4 0.0 3.5e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 T5orf172 domain Herpes_UL32 PF06070.6 KND87418.1 - 0.13 10.7 3.7 0.16 10.4 2.6 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Sugar_tr PF00083.19 KND87419.1 - 1.3e-106 356.8 17.2 1.6e-106 356.6 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND87419.1 - 8.4e-31 106.9 47.3 1.9e-28 99.1 13.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KND87419.1 - 7.6e-05 21.5 0.7 0.00016 20.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 KND87419.1 - 0.00034 18.9 2.1 0.00041 18.6 0.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KND87419.1 - 0.00041 18.8 24.4 0.00072 18.0 0.6 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein DUF3309 PF11752.3 KND87419.1 - 4.5 7.1 9.6 1.7 8.4 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) APH PF01636.18 KND87421.1 - 1.5e-11 44.4 0.0 2.8e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Aa_trans PF01490.13 KND87422.1 - 2.8e-21 75.4 30.1 4e-21 74.9 20.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans PF04082.13 KND87423.1 - 3.5e-21 75.2 0.0 5.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87423.1 - 8.8e-09 35.1 8.6 1.8e-08 34.1 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND87423.1 - 0.041 12.4 0.2 0.072 11.6 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KND87425.1 - 7.7e-20 71.6 0.0 9.9e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND87425.1 - 4.7e-11 42.8 2.0 9e-11 41.9 1.2 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND87425.1 - 3.6e-06 26.7 0.9 5.8e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KND87425.1 - 0.0006 19.5 0.2 0.0021 17.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KND87425.1 - 0.005 16.8 1.1 0.014 15.4 0.8 2.0 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KND87425.1 - 0.0081 15.2 0.3 0.018 14.1 0.2 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.21 KND87425.1 - 0.017 14.7 2.0 0.057 12.9 1.4 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KND87426.1 - 8.7e-17 60.8 1.2 3.2e-16 58.9 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KND87427.1 - 2.5e-82 276.8 24.8 3.1e-82 276.5 17.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND87427.1 - 2.8e-19 69.0 48.8 9.6e-19 67.2 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CLP_protease PF00574.18 KND87430.1 - 6.8e-68 227.9 0.2 9.3e-68 227.4 0.2 1.1 1 0 0 1 1 1 1 Clp protease ILVD_EDD PF00920.16 KND87431.1 - 1e-208 694.0 0.5 1.2e-208 693.7 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family Acyltransferase PF01553.16 KND87432.1 - 3.2e-06 26.5 0.0 6.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 KND87433.1 - 8.2e-106 353.4 0.5 8.2e-106 353.4 0.4 1.8 2 0 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 KND87433.1 - 8.1e-08 31.1 38.6 8.1e-08 31.1 26.8 2.1 2 1 0 2 2 2 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KND87433.1 - 0.012 14.7 9.9 0.011 14.9 3.6 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein LPP PF04728.8 KND87433.1 - 0.05 13.4 3.7 0.055 13.2 0.3 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.13 KND87433.1 - 0.43 10.0 40.3 0.42 10.1 12.2 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Sipho_Gp157 PF05565.6 KND87433.1 - 0.46 10.0 21.2 0.059 12.9 1.0 3.4 2 1 0 3 3 3 0 Siphovirus Gp157 Baculo_PEP_C PF04513.7 KND87433.1 - 4.4 7.1 11.2 61 3.4 4.1 3.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus p450 PF00067.17 KND87434.1 - 4.8e-15 55.0 0.0 5.3e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF782 PF05614.6 KND87434.1 - 0.055 13.6 0.1 0.097 12.8 0.1 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) Flu_M1 PF00598.14 KND87434.1 - 0.14 11.6 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) p450 PF00067.17 KND87435.1 - 5.8e-51 173.4 0.0 6.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_12 PF13087.1 KND87436.1 - 1.2e-34 119.5 0.0 2.8e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND87436.1 - 1.1e-18 67.6 0.0 2.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND87436.1 - 1.5e-06 27.8 0.1 7.9e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KND87436.1 - 0.00022 21.2 0.3 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 KND87436.1 - 0.00023 20.2 0.1 0.017 14.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KND87436.1 - 0.0009 18.8 0.1 0.18 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 KND87436.1 - 0.002 18.2 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain NTP_transf_3 PF12804.2 KND87436.1 - 0.0034 17.4 1.4 0.078 13.0 0.2 3.3 3 0 0 3 3 3 1 MobA-like NTP transferase domain T2SF PF00482.18 KND87436.1 - 0.26 11.1 0.4 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Amino_oxidase PF01593.19 KND87437.1 - 4.3e-50 171.1 0.2 5.2e-50 170.8 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SGL PF08450.7 KND87438.1 - 3.9e-09 36.2 0.0 4.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region AA_permease_2 PF13520.1 KND87439.1 - 1.6e-22 79.6 27.1 1.2e-11 43.8 9.7 2.0 1 1 1 2 2 2 2 Amino acid permease Amino_oxidase PF01593.19 KND87440.1 - 5.5e-05 22.4 0.0 8.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND87440.1 - 0.019 14.9 0.2 0.064 13.2 0.0 1.9 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain AMP-binding PF00501.23 KND87442.1 - 2.3e-49 167.9 0.0 3.2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND87442.1 - 3.8e-10 40.5 0.1 9.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain P4Ha_N PF08336.6 KND87443.1 - 0.02 14.6 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CobU PF02283.11 KND87443.1 - 0.18 11.2 0.6 0.28 10.5 0.4 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Aldedh PF00171.17 KND87444.1 - 2.8e-142 474.3 0.0 3.4e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KND87444.1 - 0.00013 20.8 0.0 0.00021 20.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MAM33 PF02330.11 KND87445.1 - 1.9e-30 106.2 4.8 1.2e-20 74.1 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein Oxysterol_BP PF01237.13 KND87446.1 - 6.5e-54 182.7 0.0 8.1e-44 149.5 0.0 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein AAA PF00004.24 KND87447.1 - 5.6e-41 139.8 0.0 9.9e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND87447.1 - 1.4e-06 28.4 0.1 0.00035 20.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KND87447.1 - 4.8e-06 26.5 0.0 9.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KND87447.1 - 1.5e-05 24.0 0.0 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KND87447.1 - 0.0001 22.0 0.1 0.00035 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KND87447.1 - 0.00042 20.3 0.1 0.0017 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KND87447.1 - 0.00056 19.0 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KND87447.1 - 0.0018 18.2 0.2 0.0056 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KND87447.1 - 0.0047 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND87447.1 - 0.0053 17.5 0.2 0.015 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND87447.1 - 0.007 16.0 0.2 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KND87447.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KND87447.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KND87447.1 - 0.011 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 KND87447.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KND87447.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KND87447.1 - 0.017 13.8 0.0 0.036 12.7 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 KND87447.1 - 0.021 14.4 0.1 0.38 10.4 0.1 2.5 2 1 1 3 3 2 0 NACHT domain PhoH PF02562.11 KND87447.1 - 0.022 13.9 2.0 0.24 10.6 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 KND87447.1 - 0.047 12.5 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KND87447.1 - 0.053 13.6 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KND87447.1 - 0.06 12.9 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KND87447.1 - 0.061 12.4 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KND87447.1 - 0.089 11.8 0.0 0.46 9.5 0.0 2.0 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 KND87447.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KND87447.1 - 0.25 10.6 4.6 0.27 10.5 0.3 2.5 2 1 1 3 3 2 0 AAA domain CHD5 PF04420.9 KND87448.1 - 0.76 9.4 2.9 0.99 9.0 2.0 1.2 1 0 0 1 1 1 0 CHD5-like protein p450 PF00067.17 KND87450.1 - 1.7e-38 132.3 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.15 KND87450.1 - 1.6e-32 113.4 0.1 3e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KND87450.1 - 3.6e-14 53.4 7.7 3.3e-13 50.3 5.3 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KND87450.1 - 1.2e-12 47.4 0.0 4.4e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KND87450.1 - 8.1e-06 25.2 1.1 0.0012 18.1 0.2 2.4 2 0 0 2 2 2 2 Amidohydrolase family Mito_carr PF00153.22 KND87451.1 - 1.1e-15 57.0 0.0 7.3e-10 38.4 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein Methyltransf_18 PF12847.2 KND87452.1 - 2.3e-10 41.0 0.0 4.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND87452.1 - 3.2e-10 39.9 0.0 5.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND87452.1 - 1.8e-09 37.8 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87452.1 - 6e-08 33.0 0.0 1.3e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND87452.1 - 1.8e-07 31.2 0.0 2.8e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87452.1 - 3.4e-06 27.4 0.0 9.5e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87452.1 - 3.6e-06 26.6 0.0 5.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KND87452.1 - 0.0088 15.7 0.0 0.022 14.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 KND87452.1 - 0.0097 15.2 0.0 0.06 12.6 0.0 2.0 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 KND87452.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 KND87452.1 - 0.033 15.0 0.0 0.1 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KND87452.1 - 0.094 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KND87452.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Complex1_LYR_2 PF13233.1 KND87453.1 - 0.00013 22.3 0.0 0.00015 22.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KND87453.1 - 0.002 17.8 0.2 0.0027 17.4 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND87453.1 - 0.099 12.8 0.2 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Exo_endo_phos PF03372.18 KND87455.1 - 3.8e-21 76.1 0.1 7.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KND87455.1 - 1.1e-13 50.4 10.1 5.2e-08 32.3 0.3 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND87455.1 - 5e-07 29.3 7.5 2.6e-05 23.8 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KND87455.1 - 1.5e-05 24.3 8.1 0.064 13.3 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KND87455.1 - 0.0057 16.6 6.5 12 6.6 0.0 4.3 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 KND87455.1 - 0.082 13.0 0.8 3.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Herpes_LMP2 PF07415.6 KND87455.1 - 0.93 8.0 2.4 1.4 7.4 1.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Exo_endo_phos PF03372.18 KND87456.1 - 3.8e-21 76.1 0.1 7.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KND87456.1 - 1.1e-13 50.4 10.1 5.2e-08 32.3 0.3 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND87456.1 - 5e-07 29.3 7.5 2.6e-05 23.8 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KND87456.1 - 1.5e-05 24.3 8.1 0.064 13.3 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KND87456.1 - 0.0057 16.6 6.5 12 6.6 0.0 4.3 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 KND87456.1 - 0.082 13.0 0.8 3.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Herpes_LMP2 PF07415.6 KND87456.1 - 0.93 8.0 2.4 1.4 7.4 1.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Borrelia_P83 PF05262.6 KND87457.1 - 8.8 4.4 18.6 13 3.9 12.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RAI16-like PF10257.4 KND87458.1 - 3.7e-79 266.2 1.1 6e-79 265.5 0.8 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Mito_carr PF00153.22 KND87460.1 - 2.6e-35 120.0 1.9 2.6e-14 52.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.14 KND87462.1 - 2.3e-49 166.9 0.0 3.3e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND87462.1 - 7.4e-18 64.2 0.0 9.6e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KND87462.1 - 0.0071 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cu-oxidase PF00394.17 KND87463.1 - 3.1e-31 108.4 0.0 7.9e-30 103.8 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KND87463.1 - 6.7e-29 100.0 2.3 1.3e-27 95.8 0.1 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND87463.1 - 1.7e-22 79.3 1.9 1e-20 73.6 0.2 2.8 2 0 0 2 2 2 2 Multicopper oxidase Methyltransf_23 PF13489.1 KND87465.1 - 3.4e-22 78.8 0.0 6.1e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87465.1 - 1e-08 35.7 0.0 5.5e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87465.1 - 1.2e-08 35.3 0.0 1.4e-07 31.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87465.1 - 4.1e-07 30.3 0.0 1.2e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87465.1 - 1.3e-06 28.1 0.0 1.6e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND87465.1 - 6.7e-05 23.1 0.0 0.0002 21.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND87465.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KND87465.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 KND87465.1 - 0.15 11.1 0.0 0.54 9.3 0.0 1.8 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Ank_2 PF12796.2 KND87468.1 - 2.2e-37 127.2 2.9 1.8e-16 60.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND87468.1 - 2e-35 118.8 18.0 1.2e-08 34.3 0.0 7.6 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KND87468.1 - 2.2e-32 110.8 4.3 8.4e-11 42.0 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND87468.1 - 1.3e-29 101.5 15.8 9.8e-12 44.7 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87468.1 - 3.4e-27 91.7 5.3 7.7e-05 22.5 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat APH PF01636.18 KND87469.1 - 0.00026 20.7 0.4 0.00053 19.7 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 KND87471.1 - 6.5e-06 25.2 0.4 1.6e-05 23.8 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87471.1 - 0.079 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF89 PF01937.14 KND87472.1 - 1.1e-126 422.4 0.1 1.3e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sulfotransfer_3 PF13469.1 KND87473.1 - 5.6e-05 24.1 0.8 0.00016 22.6 0.6 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 KND87473.1 - 0.03 13.6 0.1 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain AA_permease PF00324.16 KND87474.1 - 1.6e-124 415.8 38.6 1.9e-124 415.6 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND87474.1 - 8.1e-39 133.3 46.2 1.1e-38 132.9 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease HhH-GPD PF00730.20 KND87476.1 - 5.3e-05 23.4 0.1 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KND87476.1 - 0.011 15.4 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif GMC_oxred_N PF00732.14 KND87477.1 - 1.9e-65 220.9 0.0 2.5e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND87477.1 - 1.2e-15 58.0 0.0 2.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KND87477.1 - 8.8e-05 22.4 0.0 0.00042 20.2 0.0 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KND87477.1 - 0.00027 19.9 0.1 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KND87477.1 - 0.0012 17.8 0.3 0.016 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND87477.1 - 0.0033 17.2 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KND87477.1 - 0.018 13.9 0.1 0.04 12.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KND87477.1 - 0.031 14.1 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND87477.1 - 0.034 13.2 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 KND87478.1 - 1.4e-27 96.3 0.0 1.3e-26 93.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Sod_Fe_N PF00081.17 KND87480.1 - 1.5e-31 108.4 1.2 3.1e-31 107.4 0.2 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 KND87480.1 - 9.2e-31 105.8 0.1 1.4e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain XPG_I PF00867.13 KND87481.1 - 1.4e-25 89.1 0.0 2.8e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KND87481.1 - 7.8e-05 22.2 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_11 PF13414.1 KND87481.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KND87481.1 - 0.03 14.2 0.1 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat XPG_N PF00752.12 KND87481.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain IBR PF01485.16 KND87482.1 - 3.9e-22 77.8 42.8 6.2e-12 45.2 3.7 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 KND87482.1 - 0.00019 21.4 7.2 0.00019 21.4 5.0 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND87482.1 - 0.00029 20.6 4.7 0.00029 20.6 3.3 3.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KND87482.1 - 0.00097 18.7 4.9 0.00097 18.7 3.4 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND87482.1 - 0.011 15.4 7.2 0.011 15.4 5.0 4.0 2 1 1 3 3 3 0 zinc-RING finger domain UN_NPL4 PF11543.3 KND87482.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.1 KND87482.1 - 0.18 11.7 24.0 0.38 10.6 0.3 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KND87482.1 - 1.1 8.9 39.7 0.73 9.4 6.3 3.9 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF2962 PF11176.3 KND87483.1 - 2.1e-42 144.2 0.2 2.4e-42 144.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) XPG_N PF00752.12 KND87484.1 - 1.7e-09 37.8 0.0 2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain FAM183 PF14886.1 KND87484.1 - 0.063 13.8 1.2 0.19 12.2 0.2 1.9 1 1 1 2 2 2 0 FAM183A and FAM183B related Acetyltransf_1 PF00583.19 KND87485.1 - 2.2e-05 24.3 0.0 4.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND87485.1 - 0.028 14.5 0.0 1.4 9.0 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND87485.1 - 0.083 12.6 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein TauD PF02668.11 KND87487.1 - 1.6e-21 77.1 0.0 2.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KND87487.1 - 0.0025 16.7 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 CsiD Redoxin PF08534.5 KND87488.1 - 6.2e-31 106.9 0.0 8e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KND87488.1 - 8.3e-09 35.1 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Ank_2 PF12796.2 KND87489.1 - 3.3e-26 91.4 0.2 6.7e-13 48.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND87489.1 - 1.6e-15 56.0 0.7 2.3e-08 33.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KND87489.1 - 1.6e-11 44.3 0.3 2e-08 34.5 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87489.1 - 3.4e-09 36.0 0.7 1.7e-05 24.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KND87489.1 - 6.5e-07 29.3 1.0 7.3e-05 22.8 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) APH PF01636.18 KND87491.1 - 2.3e-09 37.3 0.0 3.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87491.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KND87491.1 - 0.029 13.7 0.1 0.07 12.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family He_PIG PF05345.7 KND87491.1 - 0.063 13.3 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative Ig domain DUF1679 PF07914.6 KND87491.1 - 0.091 11.3 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) zf-C2H2_4 PF13894.1 KND87492.1 - 0.00024 21.2 11.7 0.0025 18.0 0.4 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KND87492.1 - 0.28 11.5 12.4 1.8 9.0 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type RINGv PF12906.2 KND87493.1 - 0.00016 21.6 8.1 0.00029 20.8 5.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KND87493.1 - 0.0019 18.0 10.1 0.0019 18.0 7.0 1.9 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 KND87493.1 - 0.071 13.0 5.4 0.13 12.2 3.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KND87493.1 - 0.073 13.1 4.2 0.14 12.2 2.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KND87493.1 - 0.85 9.3 6.2 1.6 8.4 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KND87493.1 - 1.5 8.4 8.3 2.8 7.5 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KND87493.1 - 6.2 6.5 8.2 11 5.7 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.13 KND87494.1 - 5.1e-18 64.8 0.2 8.2e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KND87495.1 - 4.2e-86 287.4 46.8 8.9e-45 152.4 14.6 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KND87495.1 - 6.5e-38 130.1 0.0 1.5e-17 64.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KND87495.1 - 2.6e-28 97.7 2.5 2.9e-26 91.1 0.0 2.9 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KND87495.1 - 2.9e-09 36.4 32.9 4.2e-05 22.7 10.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KND87495.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KND87495.1 - 7.1e-05 22.0 0.0 0.0051 16.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND87495.1 - 0.00044 20.2 1.0 0.058 13.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KND87495.1 - 0.00077 18.9 0.0 0.3 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KND87495.1 - 0.0014 18.1 0.1 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KND87495.1 - 0.0023 17.3 0.6 1.7 8.0 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KND87495.1 - 0.0028 17.8 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KND87495.1 - 0.0093 15.8 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND87495.1 - 0.065 13.5 0.4 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KND87495.1 - 0.08 11.8 0.1 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 KND87495.1 - 0.14 12.1 0.7 14 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KND87495.1 - 0.23 11.2 0.9 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 KND87495.1 - 0.24 10.8 0.4 25 4.3 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Myc_target_1 PF15179.1 KND87496.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Myc target protein 1 DUF1525 PF07511.6 KND87497.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF1446 PF07287.6 KND87498.1 - 2.3e-117 391.5 0.0 3.3e-117 391.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) PUCC PF03209.10 KND87498.1 - 0.68 8.5 2.3 1.1 7.9 1.6 1.2 1 0 0 1 1 1 0 PUCC protein zf-C2H2 PF00096.21 KND87499.1 - 1.1 9.7 8.1 9.8 6.7 1.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND87499.1 - 5.1 7.6 10.8 2.3 8.7 0.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Cutinase PF01083.17 KND87502.1 - 2.7e-37 128.2 6.1 2.7e-37 128.2 4.2 1.7 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.6 KND87502.1 - 2.3e-07 30.4 1.0 5.6e-07 29.2 0.2 1.9 1 1 1 2 2 2 1 PE-PPE domain VWA_2 PF13519.1 KND87502.1 - 0.015 15.4 1.4 0.71 9.9 1.0 2.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Abhydrolase_5 PF12695.2 KND87502.1 - 0.18 11.5 9.8 0.015 15.0 2.7 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family DNA_pol_B_palm PF14792.1 KND87503.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm SRI PF08236.6 KND87503.1 - 0.038 13.9 0.1 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain CoA_transf_3 PF02515.12 KND87504.1 - 6.2e-38 129.9 0.3 8.7e-38 129.4 0.2 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF2285 PF10074.4 KND87504.1 - 0.73 10.1 3.5 0.63 10.4 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) MFS_1 PF07690.11 KND87505.1 - 1.7e-33 115.7 65.5 3.8e-32 111.3 45.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2755 PF10954.3 KND87505.1 - 1.4 8.6 7.4 6.8 6.4 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2755) Herpes_gE PF02480.11 KND87506.1 - 0.00043 18.6 0.0 0.00062 18.1 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 KND87506.1 - 0.0061 15.9 11.8 0.007 15.8 8.2 1.1 1 0 0 1 1 1 1 Vta1 like DUF4366 PF14283.1 KND87506.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Mito_fiss_reg PF05308.6 KND87506.1 - 0.01 15.2 7.9 0.014 14.7 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Plasmodium_Vir PF05795.6 KND87506.1 - 0.048 12.8 0.5 0.065 12.4 0.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PRCC PF10253.4 KND87506.1 - 0.057 14.0 6.2 0.078 13.6 4.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Phage_HK97_TLTM PF06120.6 KND87506.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein TrbC PF04956.8 KND87506.1 - 0.59 10.1 4.7 0.68 9.9 0.0 2.4 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF566 PF04484.7 KND87506.1 - 8 5.8 22.3 11 5.3 15.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Sulfotransfer_3 PF13469.1 KND87507.1 - 0.00014 22.7 4.0 0.0003 21.7 2.7 1.8 1 1 0 1 1 1 1 Sulfotransferase family GalKase_gal_bdg PF10509.4 KND87508.1 - 2.4e-20 71.5 0.0 5.8e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KND87508.1 - 4.8e-15 55.3 1.1 1.5e-14 53.8 0.8 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND87508.1 - 5.4e-14 52.1 0.0 1.8e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal ABC_tran PF00005.22 KND87509.1 - 1.8e-16 60.6 0.1 2.7e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND87509.1 - 6.2e-06 26.3 0.1 0.001 19.0 0.0 2.0 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 KND87509.1 - 0.00013 21.3 0.6 0.00042 19.6 0.4 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KND87509.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 KND87510.1 - 1.4e-10 41.0 1.8 1.7e-10 40.7 1.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Renin_r PF07850.9 KND87510.1 - 0.086 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Renin receptor-like protein DUF706 PF05153.10 KND87511.1 - 3e-125 416.6 0.3 4.2e-125 416.1 0.1 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF706) ABC_tran PF00005.22 KND87512.1 - 7.7e-33 113.6 0.0 4.3e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KND87512.1 - 5.5e-10 39.1 8.7 1.2e-09 38.0 6.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KND87512.1 - 6.1e-05 23.1 0.0 0.0034 17.3 0.0 2.2 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KND87512.1 - 0.00019 20.7 0.0 0.0012 18.1 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain PAM2 PF07145.10 KND87512.1 - 0.00037 19.8 0.0 0.0008 18.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Zeta_toxin PF06414.7 KND87512.1 - 0.00048 19.2 0.0 0.0017 17.5 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KND87512.1 - 0.001 19.9 0.0 0.0024 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND87512.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KND87512.1 - 0.0049 16.3 0.3 0.014 14.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KND87512.1 - 0.081 12.3 0.2 0.48 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KND87512.1 - 0.082 12.8 0.6 0.41 10.5 0.1 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Coleoptericin PF06286.6 KND87512.1 - 0.13 12.1 0.8 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Coleoptericin DUF2964 PF11177.3 KND87512.1 - 0.37 10.7 3.8 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) TPR_11 PF13414.1 KND87514.1 - 8.6e-19 66.9 8.8 3.6e-16 58.5 3.5 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KND87514.1 - 9e-15 53.5 5.3 1.1e-07 31.1 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND87514.1 - 2.4e-13 48.8 8.6 4.8e-06 26.0 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND87514.1 - 9.5e-10 38.8 12.9 4.5e-08 33.5 4.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND87514.1 - 1.4e-07 31.1 5.1 0.011 15.8 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND87514.1 - 7.4e-06 26.1 12.1 0.0036 17.8 0.8 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND87514.1 - 3.1e-05 23.4 1.0 0.024 14.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND87514.1 - 4.6e-05 23.2 7.1 0.011 15.6 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND87514.1 - 0.00019 21.6 2.7 0.00019 21.6 1.9 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND87514.1 - 0.0024 17.6 10.2 0.0082 15.9 0.9 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat XPC-binding PF09280.6 KND87514.1 - 0.047 13.1 5.0 0.041 13.3 2.1 1.9 2 0 0 2 2 2 0 XPC-binding domain TPR_10 PF13374.1 KND87514.1 - 0.066 13.1 3.5 1.3 9.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 KND87514.1 - 0.12 12.6 3.0 8.3 6.7 0.6 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 KND87514.1 - 0.18 12.3 8.4 2 9.0 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND87514.1 - 1.8 8.4 6.7 13 5.8 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Vps35 PF03635.12 KND87515.1 - 0 1016.5 0.0 0 1016.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Acetyltransf_1 PF00583.19 KND87516.1 - 3.4e-08 33.4 0.1 5.4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND87516.1 - 0.00036 20.6 0.1 0.00074 19.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND87516.1 - 0.017 14.9 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KND87516.1 - 0.062 13.4 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NST1 PF13945.1 KND87517.1 - 3.2e-53 180.6 4.8 3.2e-53 180.6 3.3 4.8 2 2 3 5 5 5 1 Salt tolerance down-regulator NARP1 PF12569.3 KND87518.1 - 7.2e-185 615.6 28.7 1.2e-182 608.2 15.1 2.5 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KND87518.1 - 4.3e-25 87.8 21.4 0.00019 21.7 0.0 7.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KND87518.1 - 1.1e-16 60.9 26.1 0.00029 21.4 0.1 8.4 6 2 5 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KND87518.1 - 3e-16 58.4 21.3 0.0007 20.0 0.0 10.7 6 4 7 13 13 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 KND87518.1 - 3e-16 58.8 31.5 3.2e-06 26.7 0.3 7.9 7 2 1 8 8 8 6 TPR repeat TPR_2 PF07719.12 KND87518.1 - 9.8e-15 53.2 19.4 0.00014 21.4 0.2 9.9 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND87518.1 - 2.7e-11 42.5 17.8 1.6e-05 24.2 0.4 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND87518.1 - 8.6e-10 38.3 12.4 9.2e-06 25.4 0.3 5.8 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND87518.1 - 2.3e-09 36.7 10.8 0.4 11.0 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND87518.1 - 3e-09 36.6 21.1 0.0038 17.1 0.0 7.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KND87518.1 - 0.0029 17.2 0.0 0.0029 17.2 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_3 PF07720.7 KND87518.1 - 0.0038 16.9 0.6 0.14 11.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KND87518.1 - 0.03 13.3 25.1 0.2 10.6 0.8 4.9 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND87518.1 - 0.041 13.8 11.5 2.3 8.2 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1758 PF05585.7 KND87518.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Alpha_E3_glycop PF01563.11 KND87518.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein TPR_7 PF13176.1 KND87518.1 - 0.17 11.7 14.9 2.7 7.9 0.0 7.3 9 1 0 9 9 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND87518.1 - 0.26 11.8 13.2 2.6 8.6 0.1 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KND87518.1 - 2.7 7.9 12.7 15 5.5 0.1 5.8 6 1 1 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.4 KND87519.1 - 2.4e-47 160.7 0.0 2.8e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DAGK_cat PF00781.19 KND87520.1 - 9.4e-28 96.2 0.0 1.7e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PerB PF06590.6 KND87520.1 - 0.1 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 PerB protein BCS1_N PF08740.6 KND87521.1 - 1.3e-41 142.2 0.0 1.8e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KND87521.1 - 3.3e-17 62.9 0.0 5.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND87521.1 - 1.1e-05 26.2 0.0 2.7e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND87521.1 - 0.0001 21.7 0.0 0.00031 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND87521.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND87521.1 - 0.0025 17.5 0.0 0.013 15.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KND87521.1 - 0.0036 16.8 0.0 0.0089 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KND87521.1 - 0.0074 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KND87521.1 - 0.0081 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 KND87521.1 - 0.0094 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_21 PF13304.1 KND87521.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KND87521.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 KND87521.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 KND87521.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 KND87521.1 - 0.022 14.7 0.1 0.12 12.3 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KND87521.1 - 0.023 15.0 0.0 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KND87521.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KND87521.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KND87521.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KND87521.1 - 0.17 11.5 0.0 2.8 7.5 0.0 2.7 4 0 0 4 4 3 0 NACHT domain DUF2263 PF10021.4 KND87522.1 - 2e-27 96.0 0.0 3.5e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Oxysterol_BP PF01237.13 KND87523.1 - 9.9e-88 293.9 0.0 1.2e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein F_bP_aldolase PF01116.15 KND87524.1 - 2.2e-95 319.0 0.0 2.6e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II BTB PF00651.26 KND87525.1 - 3.9e-06 26.8 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ECH PF00378.15 KND87525.1 - 0.037 13.1 0.0 0.063 12.3 0.0 1.4 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Amidohydro_1 PF01979.15 KND87526.1 - 2.1e-31 109.8 0.3 2.6e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KND87526.1 - 1.9e-07 31.4 2.1 0.0008 19.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KND87526.1 - 7.9e-06 25.5 0.0 2.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KND87526.1 - 1.6e-05 24.3 6.2 0.00049 19.4 0.0 3.0 3 1 0 4 4 4 2 Amidohydrolase family A_deaminase PF00962.17 KND87526.1 - 0.098 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Auxin_canalis PF05703.6 KND87528.1 - 0.062 13.1 0.2 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Auxin canalisation BOP1NT PF08145.7 KND87529.1 - 6.9e-105 350.4 3.1 9.7e-105 349.9 2.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KND87529.1 - 3.4e-31 105.9 2.9 5.7e-15 54.5 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat NPCBM_assoc PF10633.4 KND87529.1 - 0.055 13.5 0.2 16 5.6 0.0 3.2 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Ish1 PF10281.4 KND87530.1 - 1.5e-73 242.4 19.4 3.4e-13 49.3 0.0 9.1 9 0 0 9 9 9 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KND87530.1 - 3.4e-12 45.5 0.0 0.089 12.3 0.0 7.6 8 0 0 8 8 8 3 SAP domain Slx4 PF09494.5 KND87530.1 - 7.5e-08 32.0 0.4 4.7 7.0 0.0 6.1 6 0 0 6 6 6 2 Slx4 endonuclease HeH PF12949.2 KND87530.1 - 7.4e-06 25.4 0.0 4.6 6.8 0.0 5.8 6 0 0 6 6 6 1 HeH/LEM domain DUF3612 PF12268.3 KND87530.1 - 0.0012 18.6 0.1 9.8 5.9 0.0 4.8 5 1 1 6 6 6 1 Protein of unknown function (DUF3612) SpoU_methylas_C PF12105.3 KND87530.1 - 0.011 15.3 0.0 75 2.9 0.0 4.9 6 0 0 6 6 6 0 SpoU, rRNA methylase, C-terminal DUF905 PF06006.7 KND87530.1 - 0.024 14.0 0.2 0.34 10.2 0.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Lipase3_N PF03893.11 KND87530.1 - 0.037 13.8 0.5 0.13 12.0 0.3 1.9 1 0 0 1 1 1 0 Lipase 3 N-terminal region EF-hand_9 PF14658.1 KND87530.1 - 0.067 13.1 0.0 24 4.9 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain TilS PF09179.6 KND87530.1 - 0.15 12.1 1.3 19 5.3 0.0 4.0 6 0 0 6 6 6 0 TilS substrate binding domain ArfGap PF01412.13 KND87530.1 - 3.5 7.4 7.2 56 3.5 0.5 3.8 2 2 1 3 3 3 0 Putative GTPase activating protein for Arf AAA PF00004.24 KND87531.1 - 1e-39 135.7 0.0 2.1e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND87531.1 - 0.00018 21.2 0.0 0.00087 19.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KND87531.1 - 0.0004 19.4 0.0 0.00084 18.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND87531.1 - 0.00063 19.7 0.1 0.046 13.7 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND87531.1 - 0.0007 19.7 0.1 0.03 14.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KND87531.1 - 0.0012 18.7 0.1 0.0084 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KND87531.1 - 0.0094 15.1 0.3 0.077 12.2 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 KND87531.1 - 0.011 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KND87531.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KND87531.1 - 0.024 14.3 0.2 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 KND87531.1 - 0.03 13.2 0.0 0.072 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KND87531.1 - 0.047 13.1 0.1 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KND87531.1 - 0.055 12.8 1.0 0.53 9.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KND87531.1 - 0.06 12.9 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KND87531.1 - 0.097 13.4 0.1 0.097 13.4 0.1 2.7 2 2 0 2 2 2 0 AAA domain Ribosomal_L10 PF00466.15 KND87532.1 - 0.0027 17.5 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Tic20 PF09685.5 KND87533.1 - 1.8e-07 31.1 2.3 2.4e-07 30.6 1.6 1.1 1 0 0 1 1 1 1 Tic20-like protein Reticulon PF02453.12 KND87533.1 - 0.036 13.6 0.6 0.051 13.1 0.4 1.2 1 0 0 1 1 1 0 Reticulon SAC3_GANP PF03399.11 KND87534.1 - 0.00091 18.8 0.1 0.0025 17.4 0.1 1.6 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KND87534.1 - 0.0036 17.0 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Frankia_peptide PF14407.1 KND87534.1 - 0.099 12.4 0.5 0.24 11.1 0.2 1.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Glycos_trans_3N PF02885.12 KND87534.1 - 0.12 11.9 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain MRP-L28 PF09812.4 KND87535.1 - 0.00061 19.6 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 AGTRAP PF06396.6 KND87536.1 - 0.001 18.7 0.7 0.001 18.7 0.5 1.6 2 0 0 2 2 2 1 Angiotensin II, type I receptor-associated protein (AGTRAP) AMP-binding PF00501.23 KND87537.1 - 4.7e-101 338.1 0.8 1.7e-57 194.7 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 KND87537.1 - 2.4e-23 82.1 0.1 2.3e-10 40.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site MEDS PF14417.1 KND87538.1 - 0.063 12.3 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MFS_1 PF07690.11 KND87539.1 - 1.2e-10 40.6 14.6 1.2e-10 40.6 10.1 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Arylsulfotran_2 PF14269.1 KND87540.1 - 8.1e-47 159.8 0.0 1.2e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KND87540.1 - 2e-25 89.2 0.3 5e-25 87.9 0.2 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ank_4 PF13637.1 KND87541.1 - 3.4e-36 122.9 1.6 2.1e-14 53.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KND87541.1 - 5.7e-34 114.2 1.9 7.3e-08 31.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KND87541.1 - 7.7e-32 109.4 0.2 1.9e-17 63.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KND87541.1 - 1.4e-22 77.4 0.2 0.00018 21.4 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KND87541.1 - 1.3e-20 72.9 2.4 2.5e-10 40.2 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DAO PF01266.19 KND87542.1 - 0.13 11.1 1.3 0.25 10.1 0.9 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Cyclase PF04199.8 KND87543.1 - 5e-16 58.8 0.0 8.2e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 KND87544.1 - 7.4e-86 288.4 25.1 8.5e-86 288.3 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND87544.1 - 1.5e-29 102.8 35.6 6.5e-22 77.7 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos_2 PF12850.2 KND87545.1 - 1e-07 31.9 0.1 1.9e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND87545.1 - 0.00011 21.6 0.3 0.00034 20.0 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4470 PF14737.1 KND87546.1 - 8.7e-22 76.7 0.0 1.9e-21 75.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KND87546.1 - 1.8e-08 34.0 9.6 3.3e-08 33.2 6.7 1.4 1 0 0 1 1 1 1 MYND finger Cauli_AT PF03233.8 KND87546.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein adh_short PF00106.20 KND87547.1 - 2.1e-05 24.4 0.1 7.5e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KND87547.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND87547.1 - 0.00065 19.1 0.0 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KND87547.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TPP_enzyme_N PF02776.13 KND87548.1 - 7.1e-58 194.8 0.0 9.6e-57 191.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KND87548.1 - 4.3e-49 165.9 0.1 2.7e-47 160.1 0.0 2.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KND87548.1 - 1.3e-37 128.5 0.4 1.3e-37 128.5 0.3 2.4 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain VPS9 PF02204.13 KND87549.1 - 8.3e-17 61.1 0.0 2.1e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KND87549.1 - 7.6e-15 54.6 0.4 1.2e-11 44.4 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND87549.1 - 1.5e-10 41.2 0.0 4.6e-06 26.8 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND87549.1 - 5.7e-09 36.2 0.4 0.00022 21.6 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87549.1 - 2.5e-06 27.1 0.1 0.41 11.0 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 KND87549.1 - 1.7e-05 24.3 1.1 0.018 14.7 0.0 4.2 6 0 0 6 6 6 1 Ankyrin repeat PX PF00787.19 KND87549.1 - 0.00037 20.2 0.0 0.00095 18.9 0.0 1.7 1 0 0 1 1 1 1 PX domain AA_permease PF00324.16 KND87550.1 - 5.1e-103 344.9 36.0 5.7e-103 344.8 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND87550.1 - 3.2e-24 85.2 40.9 4.2e-24 84.8 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_C97 PF05903.9 KND87551.1 - 4.2e-33 114.2 0.0 5.4e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KND87551.1 - 0.0034 17.3 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.14 KND87552.1 - 6.4e-08 32.7 0.2 1.7e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 YchF-GTPase_C PF06071.8 KND87553.1 - 1e-32 111.7 0.3 2.3e-32 110.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KND87553.1 - 1.4e-11 44.3 0.0 2.7e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND87553.1 - 0.00076 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KND87553.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 TGS domain PPAK PF02818.10 KND87553.1 - 0.013 15.3 2.2 0.052 13.4 1.5 2.1 1 0 0 1 1 1 0 PPAK motif MobB PF03205.9 KND87553.1 - 0.067 12.9 0.4 4.9 6.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B BetaGal_dom3 PF13363.1 KND87553.1 - 0.089 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Dynamin_N PF00350.18 KND87553.1 - 0.11 12.3 0.1 1.8 8.3 0.0 2.5 2 1 0 3 3 3 0 Dynamin family AAA_23 PF13476.1 KND87553.1 - 0.77 10.0 6.1 6.2 7.0 4.2 2.2 1 1 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.3 KND87553.1 - 4.4 6.9 8.2 3.2 7.3 0.1 3.1 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus II TFR_dimer PF04253.10 KND87555.1 - 2.6e-25 88.4 0.0 4.2e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KND87555.1 - 8.2e-19 68.0 0.0 3e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 KND87555.1 - 1.6e-07 30.9 0.1 4.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 KND87555.1 - 0.26 10.5 0.0 0.54 9.4 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Cyt-b5 PF00173.23 KND87556.1 - 5.7e-12 45.2 0.0 7.6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1768 PF08719.6 KND87557.1 - 9.2e-52 174.9 0.0 1.1e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.10 KND87558.1 - 6.8e-30 103.9 0.0 6.3e-29 100.8 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain UPF0020 PF01170.13 KND87559.1 - 8.7e-09 35.1 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KND87559.1 - 1.8e-07 31.1 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ribonuc_P_40 PF08584.6 KND87560.1 - 2.8e-65 220.1 0.0 4.6e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ribosomal_L40e PF01020.12 KND87560.1 - 0.13 11.8 0.1 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L40e family Mago_nashi PF02792.9 KND87561.1 - 1.2e-73 245.5 0.5 1.4e-73 245.2 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 KND87562.1 - 1.3e-64 216.9 0.7 1.6e-64 216.6 0.5 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Rad60-SLD PF11976.3 KND87563.1 - 4e-06 26.4 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KND87563.1 - 2.3e-05 23.6 0.0 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF4141 PF13605.1 KND87563.1 - 0.00091 18.3 0.2 0.0037 16.4 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4141) DUF2407 PF10302.4 KND87563.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KND87563.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ank_5 PF13857.1 KND87566.1 - 1.1e-10 41.4 0.1 4.8e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND87566.1 - 7.2e-05 23.0 0.1 0.00071 19.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND87566.1 - 0.00011 22.6 0.0 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87566.1 - 0.00017 21.4 1.3 0.00097 19.1 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KND87566.1 - 0.0061 16.3 0.1 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat RNA_lig_T4_1 PF09511.5 KND87567.1 - 3e-78 262.3 0.0 4.8e-78 261.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KND87567.1 - 4.6e-72 242.3 0.0 6.4e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KND87567.1 - 3.4e-53 179.9 0.0 6.7e-53 178.9 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain ABC_tran PF00005.22 KND87567.1 - 0.059 13.6 0.2 0.28 11.4 0.0 2.2 3 0 0 3 3 3 0 ABC transporter Fis1_TPR_C PF14853.1 KND87569.1 - 0.062 13.1 0.2 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.17 KND87571.1 - 1.1e-45 154.9 0.0 1.2e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND87571.1 - 2.2e-16 60.4 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND87571.1 - 5.7e-06 25.6 0.0 8.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND87571.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KND87571.1 - 0.022 14.2 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KND87571.1 - 0.091 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.19 KND87572.1 - 1.1e-25 90.2 39.4 2.1e-12 46.3 10.2 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KND87572.1 - 2.4e-11 42.9 53.1 2.4e-05 23.2 15.0 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2929 PF11151.3 KND87572.1 - 0.015 15.3 0.1 0.015 15.3 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) DUF3451 PF11933.3 KND87572.1 - 0.093 12.5 0.4 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) UEV PF05743.8 KND87573.1 - 9.9e-37 125.3 0.0 1.5e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KND87573.1 - 4.1e-23 80.7 0.0 1.7e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 KND87573.1 - 0.00083 18.8 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3407 PF11887.3 KND87573.1 - 0.045 13.0 0.5 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) STE2 PF02116.10 KND87574.1 - 4.7e-43 147.2 10.2 5.5e-43 147.0 7.0 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR RNA_pol_Rpb2_6 PF00562.23 KND87575.1 - 6e-126 420.2 0.9 2.2e-125 418.4 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KND87575.1 - 8.3e-53 178.3 0.0 1.3e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KND87575.1 - 1.1e-45 155.3 0.0 2.3e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KND87575.1 - 2.6e-30 104.4 0.0 6e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KND87575.1 - 4.2e-24 84.2 0.2 9.4e-24 83.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KND87575.1 - 9.1e-23 79.8 0.0 1.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KND87575.1 - 3e-16 58.9 0.0 8.2e-16 57.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 IDO PF01231.13 KND87576.1 - 2.1e-167 556.8 0.0 2.4e-167 556.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase V-ATPase_G PF03179.10 KND87577.1 - 4.3e-30 104.1 12.8 5.1e-30 103.8 8.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KND87577.1 - 0.003 17.3 9.2 0.003 17.3 6.4 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) Nop25 PF09805.4 KND87577.1 - 0.2 11.7 13.2 0.29 11.2 9.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Vfa1 PF08432.5 KND87577.1 - 0.23 11.4 9.8 0.27 11.2 6.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3552 PF12072.3 KND87577.1 - 0.23 10.6 15.8 0.12 11.6 8.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HrpE PF06188.7 KND87577.1 - 1.5 8.5 8.6 24 4.6 6.0 1.9 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Mgr1 PF08602.5 KND87577.1 - 1.5 7.7 5.4 1.8 7.4 3.7 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit RRF PF01765.14 KND87577.1 - 1.7 8.1 9.4 2.3 7.6 6.5 1.2 1 0 0 1 1 1 0 Ribosome recycling factor HAUS6_N PF14661.1 KND87577.1 - 2.7 7.2 8.2 3.3 6.9 5.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.17 KND87577.1 - 4.7 7.2 11.3 9.4 6.3 7.8 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ycf1 PF05758.7 KND87577.1 - 4.9 4.7 7.7 5.6 4.5 5.3 1.0 1 0 0 1 1 1 0 Ycf1 SlyX PF04102.7 KND87578.1 - 0.047 14.0 1.1 0.063 13.6 0.8 1.2 1 0 0 1 1 1 0 SlyX MFS_1 PF07690.11 KND87579.1 - 1.3e-30 106.3 50.2 4.3e-30 104.6 34.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND87579.1 - 9.2e-10 37.6 11.6 9.2e-10 37.6 8.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KND87579.1 - 3e-06 25.7 21.8 3e-06 25.7 15.1 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CTNNBL PF08216.6 KND87580.1 - 4e-33 113.2 0.0 1.8e-32 111.1 0.0 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 KND87580.1 - 0.28 11.4 12.7 0.77 10.0 0.3 3.6 3 1 0 3 3 3 0 HEAT repeats GTP_cyclohydro2 PF00925.15 KND87581.1 - 9.6e-58 194.1 0.0 4.5e-53 178.9 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase II OB_NTP_bind PF07717.11 KND87583.1 - 1.7e-27 95.4 0.0 4e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KND87583.1 - 3.9e-24 84.6 0.1 3.9e-24 84.6 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND87583.1 - 1.1e-12 47.6 0.0 2.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KND87583.1 - 3.4e-05 23.9 0.1 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 KND87583.1 - 0.00017 21.1 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KND87583.1 - 0.00039 19.4 0.6 0.00089 18.2 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KND87583.1 - 0.014 15.2 1.3 0.2 11.5 0.0 3.2 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.17 KND87583.1 - 0.018 14.4 0.1 0.047 13.1 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain GYD PF08734.6 KND87583.1 - 0.06 13.0 0.7 11 5.7 0.0 3.2 3 0 0 3 3 3 0 GYD domain ABC_tran PF00005.22 KND87583.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.3 3 1 1 4 4 4 0 ABC transporter 2OG-FeII_Oxy_3 PF13640.1 KND87584.1 - 3.7e-08 33.7 0.2 5.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KND87584.1 - 0.0011 18.5 0.5 0.0023 17.5 0.3 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 KND87585.1 - 7.6e-07 29.1 0.2 8.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87585.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase HTH_Tnp_Tc5 PF03221.11 KND87587.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain AAA_12 PF13087.1 KND87588.1 - 9.9e-31 106.6 0.0 2.3e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND87588.1 - 7.4e-28 97.7 13.8 7.9e-27 94.3 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA PF00004.24 KND87588.1 - 1.8e-21 76.6 0.0 3.8e-08 33.5 0.0 4.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KND87588.1 - 8.5e-19 67.0 2.2 2.9e-09 36.5 0.0 4.0 3 0 0 3 3 3 3 Part of AAA domain AAA_30 PF13604.1 KND87588.1 - 2.8e-15 56.4 1.1 1e-05 25.2 0.0 5.0 4 1 0 4 4 4 4 AAA domain AAA_5 PF07728.9 KND87588.1 - 1.2e-08 34.7 0.2 0.08 12.6 0.0 4.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND87588.1 - 4e-08 33.4 7.3 0.028 14.5 0.0 5.5 4 2 1 5 5 5 3 AAA domain IstB_IS21 PF01695.12 KND87588.1 - 4.6e-06 26.1 0.0 0.37 10.1 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 KND87588.1 - 7.1e-06 26.8 17.4 0.24 12.2 0.1 5.5 5 0 0 5 5 5 3 AAA domain Sigma54_activat PF00158.21 KND87588.1 - 5.5e-05 22.7 0.1 4 6.8 0.0 4.2 3 1 1 4 4 4 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KND87588.1 - 6.1e-05 22.2 0.0 1.5 7.9 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KND87588.1 - 0.0003 19.8 7.0 0.0017 17.3 0.0 4.5 6 0 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KND87588.1 - 0.00036 20.8 8.2 2.3 8.5 0.1 4.4 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 KND87588.1 - 0.00045 19.6 8.0 0.0068 15.8 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 KND87588.1 - 0.00092 19.2 17.6 0.086 12.8 0.1 4.9 5 0 0 5 5 4 3 AAA ATPase domain KaiC PF06745.8 KND87588.1 - 0.0015 17.6 0.1 3.8 6.5 0.0 3.4 3 0 0 3 3 3 1 KaiC Torsin PF06309.6 KND87588.1 - 0.0038 17.1 0.0 12 5.8 0.0 3.4 3 0 0 3 3 3 0 Torsin RNA_helicase PF00910.17 KND87588.1 - 0.0053 16.9 0.2 29 4.9 0.0 3.6 3 0 0 3 3 3 0 RNA helicase PhoH PF02562.11 KND87588.1 - 0.0059 15.8 0.3 6.3 5.9 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein AAA_33 PF13671.1 KND87588.1 - 0.018 14.9 8.6 4.5 7.1 0.0 4.4 4 0 0 4 4 3 0 AAA domain Ribosomal_L17 PF01196.14 KND87588.1 - 0.028 14.9 0.1 0.28 11.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L17 AAA_29 PF13555.1 KND87588.1 - 0.034 13.6 0.9 14 5.3 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain FeoB_N PF02421.13 KND87588.1 - 0.27 10.5 0.7 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.1 KND87588.1 - 0.44 10.0 8.5 5.9 6.4 0.8 3.9 4 1 0 4 4 3 0 AAA domain ABC_tran PF00005.22 KND87588.1 - 1.7 8.9 7.1 21 5.3 0.0 4.0 4 0 0 4 4 4 0 ABC transporter zf-FCS PF06467.9 KND87589.1 - 0.027 14.0 0.5 0.045 13.4 0.3 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF418 PF04235.7 KND87590.1 - 0.11 12.1 0.4 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) zf-C2H2_4 PF13894.1 KND87593.1 - 4e-08 33.0 18.1 0.086 13.2 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger Peptidase_C14 PF00656.17 KND87593.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KND87593.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.8 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain zf-C2H2 PF00096.21 KND87593.1 - 0.023 15.0 22.5 0.2 12.0 1.4 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type BCA_ABC_TP_C PF12399.3 KND87593.1 - 0.093 12.4 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter zf-H2C2_5 PF13909.1 KND87593.1 - 2.7 8.4 11.2 36 4.8 1.3 4.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain AMP-binding PF00501.23 KND87595.1 - 1.9e-63 214.3 0.0 2.4e-61 207.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme MFS_1 PF07690.11 KND87596.1 - 1.8e-37 128.8 50.0 1.8e-37 128.8 34.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND87596.1 - 8e-11 41.1 17.0 8e-11 41.1 11.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KND87596.1 - 0.00033 18.8 2.0 0.00033 18.8 1.4 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.3 KND87600.1 - 3.5e-09 35.7 0.3 5.1e-09 35.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA_C PF02894.12 KND87601.1 - 0.013 15.3 0.1 0.023 14.5 0.1 1.6 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Glycophorin_A PF01102.13 KND87601.1 - 0.087 12.5 0.3 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Glycophorin A DUF4126 PF13548.1 KND87601.1 - 2.6 7.4 5.0 10 5.4 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) p450 PF00067.17 KND87602.1 - 1.4e-42 145.8 0.0 8e-40 136.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Patatin PF01734.17 KND87603.1 - 8.6e-11 42.1 0.0 9.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase AA_permease_2 PF13520.1 KND87604.1 - 8.7e-52 176.0 47.8 1.1e-51 175.8 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND87604.1 - 1.6e-30 105.9 46.2 1.9e-30 105.6 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.19 KND87605.1 - 1.4e-41 143.0 0.4 6.3e-41 140.8 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND87605.1 - 1e-09 38.2 0.7 1.8e-09 37.4 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND87605.1 - 4.4e-06 25.8 0.1 0.00078 18.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KND87605.1 - 8.2e-05 21.7 0.1 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KND87605.1 - 0.0004 19.6 0.0 0.00096 18.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND87605.1 - 0.0023 18.0 0.1 0.22 11.5 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND87605.1 - 0.0041 15.6 0.0 0.091 11.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KND87605.1 - 0.0063 15.3 0.2 0.0099 14.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KND87605.1 - 0.041 12.7 0.2 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KND87605.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KND87605.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.3 KND87606.1 - 1.2e-25 89.9 5.0 7.2e-15 54.4 0.4 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87606.1 - 0.001 18.9 15.8 0.0022 17.8 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 KND87607.1 - 1.5e-28 99.7 2.8 1.5e-28 99.7 1.9 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 KND87607.1 - 4.2e-23 81.5 0.2 6.6e-23 80.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_M PF02770.14 KND87607.1 - 1.9e-20 72.0 1.0 3.9e-20 71.1 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KND87607.1 - 4.3e-13 49.8 0.1 8e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Zn_clus PF00172.13 KND87607.1 - 3.4e-08 33.2 5.8 7.9e-08 32.0 4.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_2 PF08028.6 KND87607.1 - 8.5e-05 22.8 3.6 0.00024 21.3 2.5 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.12 KND87608.1 - 6.5e-66 221.6 0.0 1.3e-65 220.6 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KND87608.1 - 4.9e-34 116.7 0.0 1.2e-33 115.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KND87608.1 - 5.5e-29 100.2 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KND87608.1 - 3.8e-13 49.5 0.0 7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KND87608.1 - 6e-11 41.8 2.4 1.3e-10 40.7 1.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KND87608.1 - 8.2e-11 41.6 0.0 1.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KND87608.1 - 2.9e-07 30.0 0.0 9.4e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KND87608.1 - 5.8e-07 28.5 0.0 1.1e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KND87608.1 - 5.8e-06 26.2 0.0 8.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KND87608.1 - 0.0062 16.0 0.0 0.026 14.0 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.14 KND87608.1 - 0.015 15.0 0.2 0.03 13.9 0.2 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Cro PF09048.5 KND87608.1 - 0.041 13.5 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 Cro Carboxyl_trans PF01039.17 KND87609.1 - 1.2e-86 291.0 0.0 3.7e-86 289.4 0.0 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.23 KND87610.1 - 8.1e-94 314.3 0.0 9.7e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND87610.1 - 4.9e-12 46.6 0.1 9.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HMGL-like PF00682.14 KND87611.1 - 8.6e-44 149.9 0.0 1.6e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 KND87611.1 - 1e-36 126.3 0.2 1.5e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FAD_binding_4 PF01565.18 KND87612.1 - 2.1e-18 66.1 0.1 4.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND87612.1 - 1.9e-08 34.1 0.3 5.5e-08 32.5 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KND87612.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding YHYH PF14240.1 KND87612.1 - 0.028 14.0 0.7 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 YHYH protein NDUF_B7 PF05676.8 KND87614.1 - 7.1e-32 108.6 3.5 8.2e-32 108.4 2.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KND87614.1 - 0.0035 17.0 2.5 0.0047 16.6 1.7 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Amidohydro_4 PF13147.1 KND87617.1 - 1.2e-29 104.2 6.1 2e-29 103.4 4.2 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KND87617.1 - 2.7e-14 53.5 0.1 1.5e-11 44.5 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KND87617.1 - 2.3e-09 36.9 6.0 3.7e-09 36.2 1.5 2.5 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND87617.1 - 2.4e-07 30.4 0.1 8e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase AAA_33 PF13671.1 KND87618.1 - 3.9e-16 59.2 0.0 7.6e-16 58.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND87618.1 - 1.2e-08 34.3 0.0 1.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KND87618.1 - 2.2e-07 31.2 0.1 3e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND87618.1 - 7.4e-07 30.0 0.3 9.4e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND87618.1 - 1.2e-05 24.6 0.0 1.6e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SKI PF01202.17 KND87618.1 - 0.00065 19.6 0.0 0.00084 19.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA PF00004.24 KND87618.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaJ PF00226.26 KND87619.1 - 7.1e-25 86.5 0.5 1.1e-24 85.9 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KND87619.1 - 3.4e-15 55.8 16.8 5.8e-15 55.0 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KND87619.1 - 2.2e-11 43.4 0.0 2.2e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 KND87619.1 - 0.00056 19.5 5.8 0.18 11.4 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 KND87619.1 - 5.5 6.8 9.8 2.1 8.1 1.8 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-LITAF-like PF10601.4 KND87619.1 - 7.3 6.5 8.9 37 4.2 0.1 3.4 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain DUF4366 PF14283.1 KND87620.1 - 0.013 14.9 0.7 0.84 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Gly-zipper_OmpA PF13436.1 KND87620.1 - 0.44 10.2 11.0 0.28 10.8 0.1 3.5 2 1 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain GST_C PF00043.20 KND87621.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND87621.1 - 5.8e-08 33.1 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND87621.1 - 1.8e-07 30.9 2.2 1.1e-06 28.3 0.1 2.3 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KND87621.1 - 2.5e-07 30.7 0.0 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KND87621.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND87621.1 - 6.8e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Peptidase_C2 PF00648.16 KND87622.1 - 2.1e-56 191.1 0.4 3e-37 128.2 0.3 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease SSP160 PF06933.6 KND87622.1 - 5.9 4.7 12.8 9.2 4.1 8.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_L32p PF01783.18 KND87626.1 - 0.3 11.3 3.8 0.58 10.3 2.6 1.5 1 0 0 1 1 1 0 Ribosomal L32p protein family Pkinase PF00069.20 KND87627.1 - 7.2e-10 38.4 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Spt5_N PF11942.3 KND87627.1 - 9.1 6.9 9.7 0.91 10.1 3.2 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.27 KND87628.1 - 6.3e-54 178.0 5.1 1.9e-09 37.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KND87628.1 - 0.00044 19.1 3.2 0.2 10.3 0.6 2.9 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 KND87628.1 - 0.07 12.5 0.7 6.8 6.0 0.0 3.0 2 1 0 2 2 2 0 PQQ-like domain SGL PF08450.7 KND87628.1 - 0.093 12.0 0.4 0.62 9.3 0.1 2.3 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region TRAPP PF04051.11 KND87629.1 - 1.4e-36 125.2 0.0 1.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Lactamase_B PF00753.22 KND87633.1 - 9.8e-16 57.9 5.0 1.2e-15 57.6 3.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND87633.1 - 0.0087 15.6 0.8 0.013 15.0 0.4 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cerato-platanin PF07249.7 KND87634.1 - 3.9e-06 26.8 0.4 5.8e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Cerato-platanin FHA PF00498.21 KND87636.1 - 5.5e-05 23.2 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain FAP PF07174.6 KND87637.1 - 7.4 5.7 16.4 9.5 5.4 11.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PseudoU_synth_2 PF00849.17 KND87638.1 - 1.6e-29 102.8 0.0 2.3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KND87638.1 - 0.0074 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.1 KND87638.1 - 0.074 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF3439 PF11921.3 KND87639.1 - 0.36 10.5 3.2 0.32 10.7 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) DUF2638 PF10937.3 KND87639.1 - 0.61 11.1 5.8 0.39 11.7 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) CENP-K PF11802.3 KND87640.1 - 0.13 11.4 0.6 0.23 10.6 0.4 1.3 1 0 0 1 1 1 0 Centromere-associated protein K bZIP_1 PF00170.16 KND87640.1 - 2.5 8.1 22.3 0.027 14.4 5.6 2.8 2 1 1 3 3 3 0 bZIP transcription factor Fungal_trans PF04082.13 KND87642.1 - 4e-13 48.8 0.0 6.1e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87642.1 - 7.3e-08 32.2 10.6 1.2e-07 31.5 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF16 PF01519.11 KND87642.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Glyco_hydro_3 PF00933.16 KND87643.1 - 1.5e-78 263.8 0.0 2.2e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND87643.1 - 6.1e-65 218.9 0.0 1.4e-64 217.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND87643.1 - 4.4e-24 84.2 0.2 3.6e-23 81.2 0.2 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KND87643.1 - 5.6e-18 64.9 0.0 9.8e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_31 PF01055.21 KND87644.1 - 1.7e-170 567.6 0.8 2.3e-170 567.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KND87644.1 - 2.4e-12 46.4 1.1 2.9e-11 43.0 0.4 3.0 3 0 0 3 3 3 1 Galactose mutarotase-like LCCL PF03815.14 KND87645.1 - 5.3e-17 61.5 0.0 8.5e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF605 PF04652.11 KND87646.1 - 0.4 10.0 30.9 1.6 8.0 18.0 2.2 2 0 0 2 2 2 0 Vta1 like Ndc1_Nup PF09531.5 KND87646.1 - 5.1 5.3 8.2 6.1 5.1 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-UBR PF02207.15 KND87647.1 - 6.8e-17 60.9 5.4 6.8e-17 60.9 3.8 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 KND87648.1 - 2.9e-137 456.9 0.0 4.8e-137 456.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KND87648.1 - 1.4e-30 106.3 33.7 1.4e-30 106.3 23.4 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KND87648.1 - 8.3e-21 74.7 0.0 1.6e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND87648.1 - 1.4e-07 30.9 0.0 7.9e-06 25.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND87648.1 - 3.7e-06 26.7 0.0 8.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KND87648.1 - 0.0025 17.3 0.2 0.017 14.6 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KND87648.1 - 0.0089 15.6 0.1 0.043 13.4 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MtrD PF04207.7 KND87649.1 - 0.91 8.8 5.6 0.2 10.9 0.4 2.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit D Sugar_tr PF00083.19 KND87650.1 - 1.1e-112 376.9 27.3 4e-112 375.0 19.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND87650.1 - 5.2e-13 48.4 40.2 8.3e-08 31.3 9.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3154 PF11351.3 KND87650.1 - 0.046 13.4 1.4 0.65 9.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Mito_carr PF00153.22 KND87653.1 - 6.5e-53 176.4 0.3 4.4e-19 67.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SPW PF03779.9 KND87653.1 - 3.1 7.2 7.0 0.61 9.5 0.6 2.8 3 0 0 3 3 3 0 SPW repeat Cu-oxidase_3 PF07732.10 KND87654.1 - 2.9e-11 43.1 0.0 5.4e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND87654.1 - 5.7e-08 32.3 0.1 0.0039 16.6 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KND87654.1 - 0.0067 16.2 0.0 0.19 11.6 0.0 2.5 2 1 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.15 KND87654.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.10 KND87656.1 - 6.3e-42 142.0 2.1 1.4e-41 140.9 0.2 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND87656.1 - 4e-29 100.8 11.0 2.2e-23 82.3 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KND87656.1 - 4.3e-11 42.9 1.0 3.8e-08 33.3 0.2 3.2 2 1 0 2 2 2 2 Multicopper oxidase F-box-like PF12937.2 KND87657.1 - 5.9e-05 22.7 0.7 5.9e-05 22.7 0.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KND87657.1 - 0.0017 17.9 0.3 0.0043 16.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain DNA_pol_A_exo1 PF01612.15 KND87658.1 - 2.8e-14 52.9 0.0 3.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Abhydrolase_6 PF12697.2 KND87659.1 - 6.8e-09 35.9 0.1 9.2e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KND87659.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND87659.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND87659.1 - 0.0015 18.1 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.18 KND87660.1 - 4e-12 46.3 0.7 2.1e-05 24.3 0.4 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KND87660.1 - 4.8e-06 26.0 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KND87660.1 - 0.037 13.5 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.20 KND87660.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3830 PF12903.2 KND87661.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Pkinase PF00069.20 KND87662.1 - 1.4e-21 76.7 0.0 1.9e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87662.1 - 4.6e-15 55.4 0.0 7.9e-15 54.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND87662.1 - 1.3e-05 24.3 0.0 3.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KND87662.1 - 0.046 13.2 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 KND87662.1 - 0.064 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KND87662.1 - 0.066 12.2 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND87662.1 - 0.068 12.8 2.3 0.93 9.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SAF_2 PF13144.1 KND87663.1 - 0.063 12.7 0.0 0.068 12.6 0.0 1.0 1 0 0 1 1 1 0 SAF-like ISN1 PF06437.6 KND87664.1 - 5.6e-169 562.1 0.0 8.4e-169 561.6 0.0 1.3 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase IBN_N PF03810.14 KND87664.1 - 9.6e-13 47.8 5.7 5.3e-12 45.4 0.1 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 KND87664.1 - 3.6e-08 32.3 0.1 8.2e-08 31.1 0.1 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KND87664.1 - 0.0062 16.4 3.1 0.01 15.7 0.0 3.0 4 0 0 4 4 4 1 Exportin 1-like protein GRIP PF01465.15 KND87664.1 - 0.029 13.8 0.0 0.15 11.6 0.0 2.3 1 0 0 1 1 1 0 GRIP domain Glyco_transf_90 PF05686.7 KND87665.1 - 2.1e-06 26.7 0.0 0.0076 14.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 Pkinase PF00069.20 KND87666.1 - 9.4e-12 44.6 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87666.1 - 1.6e-07 30.6 0.0 5.1e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND87666.1 - 0.00028 19.9 0.0 0.00071 18.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND87666.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND87667.1 - 1.2e-31 109.8 0.0 1.8e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87667.1 - 8.8e-17 61.0 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND87667.1 - 0.033 13.1 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KND87667.1 - 0.059 13.0 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PsbJ PF01788.12 KND87668.1 - 0.38 10.3 7.4 1.6 8.3 2.3 3.1 2 0 0 2 2 2 0 PsbJ DUF3487 PF11990.3 KND87669.1 - 0.0089 15.4 1.0 0.0089 15.4 0.7 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3487) DUF3863 PF12979.2 KND87669.1 - 0.15 10.6 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) XPA_C PF05181.7 KND87670.1 - 1.2e-28 98.3 2.5 2.3e-28 97.5 1.7 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KND87670.1 - 0.0094 15.6 8.2 0.02 14.5 5.7 1.6 1 0 0 1 1 1 1 XPA protein N-terminal FRG1 PF06229.7 KND87670.1 - 0.015 14.7 0.8 0.032 13.6 0.6 1.6 1 0 0 1 1 1 0 FRG1-like family zf-C3HC4_3 PF13920.1 KND87670.1 - 0.42 10.3 9.4 0.095 12.3 3.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LicD PF04991.8 KND87671.1 - 4.7e-36 124.8 5.2 8.9e-35 120.6 3.6 2.1 1 1 0 1 1 1 1 LicD family GLTT PF01744.15 KND87671.1 - 0.0017 17.6 3.1 0.0029 16.9 2.2 1.4 1 0 0 1 1 1 1 GLTT repeat (6 copies) Clathrin PF00637.15 KND87672.1 - 1.5e-22 79.7 1.3 7.8e-21 74.1 0.5 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 KND87672.1 - 6.9e-16 57.8 0.1 1.6e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 KND87672.1 - 0.002 17.9 3.1 0.0046 16.7 2.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KND87672.1 - 0.01 15.5 3.2 0.022 14.4 2.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KND87672.1 - 0.057 13.2 0.9 0.14 12.0 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Leuk-A4-hydro_C PF09127.6 KND87672.1 - 0.14 11.7 0.1 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal zf-rbx1 PF12678.2 KND87672.1 - 0.31 11.1 1.5 0.7 10.0 1.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 KND87672.1 - 0.52 10.0 6.9 0.083 12.5 1.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 KND87672.1 - 0.56 10.9 3.0 14 6.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 KND87672.1 - 6.5 6.8 7.8 4.2 7.4 2.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Striatin PF08232.7 KND87673.1 - 3.3e-35 121.3 3.9 6.1e-35 120.4 2.7 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 KND87673.1 - 1.4e-31 107.2 18.0 3.3e-08 33.1 0.1 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat IL6 PF00489.12 KND87673.1 - 0.034 13.7 0.2 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Cytochrom_D1 PF02239.11 KND87673.1 - 0.098 10.9 0.0 0.23 9.7 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF2673 PF10880.3 KND87673.1 - 0.12 12.4 0.1 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) PAT1 PF09770.4 KND87673.1 - 8.6 4.4 27.4 12 3.9 19.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HET PF06985.6 KND87674.1 - 1.2e-24 87.0 0.0 5.4e-24 84.9 0.0 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KND87675.1 - 9.5e-11 41.8 6.2 1.3e-10 41.4 2.3 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND87675.1 - 0.00028 20.6 0.9 0.00028 20.6 0.6 1.6 2 0 0 2 2 2 1 KR domain Kinesin PF00225.18 KND87678.1 - 1.7e-88 296.5 0.1 1.7e-88 296.5 0.1 2.5 2 1 0 2 2 2 1 Kinesin motor domain APH PF01636.18 KND87680.1 - 5.5e-18 65.5 0.2 1e-17 64.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND87680.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KND87680.1 - 0.13 11.2 0.0 0.37 9.7 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 KND87680.1 - 0.22 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DNA_binding_1 PF01035.15 KND87681.1 - 1.4e-21 75.9 0.2 1.9e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Folate_carrier PF01770.13 KND87681.1 - 0.18 10.3 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier APH PF01636.18 KND87685.1 - 3.7e-05 23.5 0.0 4.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ERCC4 PF02732.10 KND87686.1 - 1.8e-15 56.9 0.1 3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain His_Phos_1 PF00300.17 KND87687.1 - 5.9e-22 78.4 0.0 1.1e-21 77.5 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TPP_enzyme_N PF02776.13 KND87688.1 - 9.8e-27 93.5 6.1 1.1e-26 93.4 0.2 3.2 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KND87688.1 - 3.4e-22 78.6 0.0 8e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KND87688.1 - 3.3e-18 65.7 0.0 1.1e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF4236 PF14020.1 KND87688.1 - 0.011 15.8 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Metallophos PF00149.23 KND87689.1 - 4.1e-13 49.1 0.0 1.3e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KND87689.1 - 6.4e-13 48.5 0.0 1.3e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KND87689.1 - 7.1e-05 21.5 0.1 0.00017 20.3 0.1 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 KND87689.1 - 0.026 14.6 0.5 0.056 13.5 0.3 1.5 1 0 0 1 1 1 0 Fibronectin type III domain SDF PF00375.13 KND87689.1 - 0.23 10.1 0.4 0.41 9.3 0.3 1.3 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Peptidase_S10 PF00450.17 KND87691.1 - 5.7e-79 266.2 7.3 2.7e-78 264.0 5.1 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Rhodanese PF00581.15 KND87691.1 - 0.019 15.3 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain MFS_1 PF07690.11 KND87692.1 - 2.8e-31 108.5 33.0 4.1e-31 107.9 22.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KND87692.1 - 0.092 12.7 0.2 0.092 12.7 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_A8 PF01252.13 KND87692.1 - 8.3 6.0 11.6 1.8 8.1 0.2 3.7 3 1 0 3 3 3 0 Signal peptidase (SPase) II IMS PF00817.15 KND87693.1 - 2.3e-41 141.0 0.0 5.4e-41 139.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KND87693.1 - 1.6e-15 57.1 0.0 2.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KND87693.1 - 0.0062 16.5 0.1 0.05 13.6 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif DUF1423 PF07227.6 KND87694.1 - 0.085 11.5 0.1 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Acyl_transf_1 PF00698.16 KND87695.1 - 9e-69 232.2 0.0 1.5e-68 231.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KND87695.1 - 1.9e-56 191.4 0.1 4.6e-56 190.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KND87695.1 - 3e-54 183.4 0.1 9.9e-54 181.7 0.0 2.0 2 0 0 2 2 1 1 KR domain PS-DH PF14765.1 KND87695.1 - 1.3e-48 165.7 0.0 1.9e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KND87695.1 - 1.5e-42 145.3 0.1 4.4e-42 143.8 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND87695.1 - 2.1e-32 111.4 0.1 6.5e-32 109.8 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KND87695.1 - 1.5e-17 63.8 0.0 4.1e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KND87695.1 - 1e-14 54.1 0.0 4e-14 52.2 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KND87695.1 - 1.1e-11 44.7 0.0 4.8e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87695.1 - 3.6e-10 39.6 0.0 1.6e-09 37.5 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87695.1 - 4.1e-09 37.0 0.0 1.3e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87695.1 - 3.8e-08 33.7 0.0 1.4e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KND87695.1 - 5.6e-08 32.5 1.0 1.4e-07 31.2 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND87695.1 - 7.3e-07 30.1 0.0 4.2e-06 27.6 0.0 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KND87695.1 - 2.5e-06 27.6 0.1 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KND87695.1 - 0.00019 20.6 0.0 0.00052 19.2 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KND87695.1 - 0.013 14.5 0.2 0.027 13.4 0.2 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain NodS PF05401.6 KND87695.1 - 0.03 13.7 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 KND87695.1 - 0.03 13.7 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase DREV PF05219.7 KND87695.1 - 0.071 11.9 0.0 0.19 10.6 0.0 1.6 1 0 0 1 1 1 0 DREV methyltransferase Shikimate_DH PF01488.15 KND87695.1 - 0.08 13.0 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KND87695.1 - 0.11 11.6 0.8 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family RrnaAD PF00398.15 KND87695.1 - 0.24 10.3 0.0 0.43 9.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.17 KND87698.1 - 2.1e-37 128.7 0.0 4.2e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 KND87699.1 - 8.6e-20 70.7 27.6 8.6e-20 70.7 19.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4149 PF13664.1 KND87699.1 - 0.068 13.2 6.9 0.028 14.4 1.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) SDA1 PF05285.7 KND87700.1 - 5.8e-73 245.9 48.1 2.2e-39 135.6 9.4 3.4 3 1 1 4 4 4 3 SDA1 NUC130_3NT PF08158.7 KND87700.1 - 8.1e-21 74.0 0.3 2.1e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 NUC130/3NT domain Mito_carr PF00153.22 KND87701.1 - 8.4e-46 153.6 8.1 3.3e-17 61.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EI24 PF07264.6 KND87702.1 - 0.012 15.0 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) ADH_N PF08240.7 KND87704.1 - 2.7e-20 72.1 2.9 4.1e-20 71.5 2.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND87704.1 - 1.7e-18 66.4 0.0 2.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND87704.1 - 5.3e-07 30.5 0.0 1.3e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KND87704.1 - 0.0063 15.6 0.1 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 KND87704.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Ank_2 PF12796.2 KND87706.1 - 6.5e-19 68.0 0.3 3.1e-09 37.0 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND87706.1 - 6.2e-17 61.6 4.5 1.4e-06 28.6 0.0 6.4 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND87706.1 - 9.8e-17 60.6 9.9 5.3e-10 39.2 0.8 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KND87706.1 - 1.5e-15 56.0 4.4 5.1e-06 26.0 0.2 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KND87706.1 - 1.8e-10 40.0 3.6 0.00098 19.1 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat Epimerase PF01370.16 KND87707.1 - 6.2e-24 84.7 0.0 8.5e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND87707.1 - 2.4e-11 42.8 0.0 3.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND87707.1 - 6.1e-09 36.1 0.0 8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND87707.1 - 8.2e-07 28.2 0.0 0.0065 15.4 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KND87707.1 - 2.6e-05 23.2 0.0 9.8e-05 21.3 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 KND87707.1 - 5.5e-05 23.0 0.0 8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.20 KND87707.1 - 0.00034 20.5 0.0 0.0041 17.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KND87707.1 - 0.0019 17.1 0.0 0.014 14.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KND87707.1 - 0.033 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND87707.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ABC2_membrane PF01061.19 KND87708.1 - 3.8e-82 274.5 71.6 1.1e-43 148.8 16.5 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KND87708.1 - 4.7e-33 112.9 1.5 1.5e-27 95.2 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KND87708.1 - 6.9e-29 100.8 0.0 3.3e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KND87708.1 - 1.2e-11 44.2 47.2 2.6e-08 33.2 9.4 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KND87708.1 - 5.2e-09 35.7 0.1 8.3e-05 22.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain ABC_trans_N PF14510.1 KND87708.1 - 4e-08 33.2 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KND87708.1 - 9.2e-05 22.4 1.7 0.0095 15.9 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KND87708.1 - 0.00024 21.9 0.0 0.013 16.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KND87708.1 - 0.00034 20.2 0.1 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 KND87708.1 - 0.00038 19.9 0.1 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KND87708.1 - 0.00049 19.3 0.0 0.00087 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KND87708.1 - 0.00054 19.4 0.1 0.0081 15.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KND87708.1 - 0.00078 19.5 0.2 0.18 11.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KND87708.1 - 0.0011 18.6 0.5 0.11 12.1 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KND87708.1 - 0.0023 17.9 0.0 0.0079 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KND87708.1 - 0.0032 17.3 0.5 0.3 10.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KND87708.1 - 0.0039 16.9 0.7 2.1 8.1 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KND87708.1 - 0.0061 16.5 0.4 0.019 14.9 0.3 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND87708.1 - 0.017 15.4 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KND87708.1 - 0.02 15.0 0.3 2.2 8.4 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KND87708.1 - 0.021 13.7 0.0 5.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 KND87708.1 - 0.056 12.8 4.2 1.6 8.1 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain AAA_23 PF13476.1 KND87708.1 - 0.061 13.6 2.5 0.16 12.2 0.1 2.5 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 KND87708.1 - 0.091 13.2 0.1 6.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KND87708.1 - 0.1 12.0 0.3 18 4.7 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 KND87708.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KND87708.1 - 0.33 10.4 0.4 1.3 8.4 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CHASE4 PF05228.8 KND87709.1 - 0.064 12.8 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 CHASE4 domain MFS_1 PF07690.11 KND87710.1 - 2.3e-33 115.3 53.4 3.8e-31 108.0 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.8 KND87711.1 - 2.4e-29 102.3 0.0 3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KND87711.1 - 0.00047 19.9 1.2 0.00081 19.1 0.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KND87711.1 - 0.066 12.7 1.0 0.12 11.9 0.7 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.20 KND87713.1 - 6.3e-27 94.5 0.1 9.4e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND87713.1 - 4.3e-26 92.1 0.0 5.1e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND87713.1 - 2.1e-07 30.7 0.0 3.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KND87713.1 - 0.00044 19.4 0.0 0.00059 19.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF1445 PF07286.7 KND87713.1 - 0.04 13.5 0.1 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) Eno-Rase_NADH_b PF12242.3 KND87713.1 - 0.075 12.8 0.1 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF500 PF04366.7 KND87714.1 - 3.7e-45 152.4 0.2 9.8e-45 151.0 0.2 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF500) TFIIA PF03153.8 KND87714.1 - 2.4 7.9 25.9 2 8.2 17.1 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pho88 PF10032.4 KND87716.1 - 5.4e-83 276.9 1.4 6.7e-83 276.6 1.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Fungal_trans_2 PF11951.3 KND87717.1 - 1.4e-16 60.0 0.0 2.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87717.1 - 5.3e-09 35.8 13.1 7.9e-09 35.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 KND87718.1 - 1.9e-48 164.5 0.0 2.2e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Catalase-rel PF06628.7 KND87718.1 - 0.16 11.8 0.2 5.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Catalase-related immune-responsive ABC_membrane PF00664.18 KND87719.1 - 2.4e-77 260.0 41.4 1.9e-43 148.8 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND87719.1 - 8.8e-68 226.8 0.1 2.4e-32 112.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KND87719.1 - 6.3e-16 59.1 0.0 0.0055 16.6 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KND87719.1 - 8.2e-12 44.8 2.9 0.00014 21.2 0.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KND87719.1 - 1e-08 34.2 1.2 0.00029 19.5 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KND87719.1 - 8.9e-08 31.4 0.1 0.017 14.3 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KND87719.1 - 9.5e-08 31.4 0.2 0.0052 16.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KND87719.1 - 4.5e-07 30.7 0.0 0.0026 18.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KND87719.1 - 5e-07 29.8 1.4 0.00095 19.1 0.3 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KND87719.1 - 0.00016 21.1 0.2 2.2 7.6 0.0 4.0 4 0 0 4 4 4 1 AAA-like domain Dynamin_N PF00350.18 KND87719.1 - 0.00024 20.9 0.0 0.37 10.6 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 KND87719.1 - 0.00026 21.3 0.0 0.062 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KND87719.1 - 0.00039 20.5 2.3 0.24 11.5 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KND87719.1 - 0.00062 19.2 0.7 0.18 11.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KND87719.1 - 0.00064 20.0 0.0 0.08 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KND87719.1 - 0.00094 19.1 0.0 0.73 9.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KND87719.1 - 0.0023 17.5 2.0 0.1 12.1 0.1 3.2 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KND87719.1 - 0.0023 17.7 0.1 3.5 7.6 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KND87719.1 - 0.0028 16.7 0.0 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF3987 PF13148.1 KND87719.1 - 0.0036 15.9 0.0 0.35 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_33 PF13671.1 KND87719.1 - 0.0044 16.9 0.0 1.7 8.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 KND87719.1 - 0.013 15.2 0.0 0.9 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KND87719.1 - 0.024 15.1 0.0 5 7.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 KND87719.1 - 0.031 13.3 0.0 8 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 KND87719.1 - 0.035 13.9 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Mg_chelatase PF01078.16 KND87719.1 - 0.065 12.3 0.0 0.63 9.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KND87719.1 - 0.1 12.5 0.2 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KND87719.1 - 0.13 12.1 0.0 27 4.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 KND87719.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Avirulence PF03377.8 KND87720.1 - 0.055 12.1 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA FMO-like PF00743.14 KND87721.1 - 1.5e-33 115.8 0.1 1.8e-23 82.5 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND87721.1 - 1.7e-16 60.8 0.0 2.5e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND87721.1 - 1.2e-10 40.9 0.0 8.9e-09 34.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KND87721.1 - 5.3e-08 32.7 0.0 1.4e-06 28.1 0.1 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND87721.1 - 9.1e-08 32.2 0.0 8.9e-06 25.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND87721.1 - 0.00048 19.1 0.0 2.7 6.7 0.2 3.5 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND87721.1 - 0.00076 19.4 0.1 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KND87721.1 - 0.012 15.6 0.3 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KND87721.1 - 0.053 11.9 0.1 3.3 6.0 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 KND87721.1 - 0.2 10.6 0.2 1.8 7.4 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain Glyco_hydro_18 PF00704.23 KND87722.1 - 3.4e-20 72.7 7.3 4.1e-19 69.2 1.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Sugar_tr PF00083.19 KND87723.1 - 3.5e-100 335.7 27.6 4.1e-100 335.4 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND87723.1 - 2.8e-25 88.7 30.2 2.8e-25 88.7 20.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_S8 PF00082.17 KND87724.1 - 6.2e-24 84.6 0.4 1.3e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Subtilase family zf-Di19 PF05605.7 KND87725.1 - 0.078 13.1 1.9 21 5.3 0.1 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_S41 PF03572.13 KND87726.1 - 0.0014 18.1 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 TRAM_LAG1_CLN8 PF03798.11 KND87728.1 - 3.9e-45 153.8 18.4 3.9e-45 153.8 12.7 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KND87728.1 - 4.9e-19 67.5 0.1 4.9e-19 67.5 0.1 2.1 2 0 0 2 2 2 1 TRAM1-like protein DUF1282 PF06930.7 KND87728.1 - 0.97 9.0 14.9 0.15 11.6 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) Gly_transf_sug PF04488.10 KND87730.1 - 8.7e-15 54.9 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Med6 PF04934.9 KND87730.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 MED6 mediator sub complex component RRM_1 PF00076.17 KND87731.1 - 3.2e-14 52.2 0.1 2.7e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND87731.1 - 2.5e-09 36.9 0.0 4.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND87731.1 - 4.5e-05 23.2 0.0 0.00011 21.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KND87732.1 - 1.5e-10 40.4 2.3 0.0073 16.1 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat IKI3 PF04762.7 KND87732.1 - 0.0024 15.7 0.0 0.0059 14.4 0.0 1.6 2 0 0 2 2 2 1 IKI3 family Nbas_N PF15492.1 KND87732.1 - 0.0033 16.5 0.0 0.0092 15.1 0.0 1.7 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 KND87734.1 - 1.5e-102 342.4 0.1 8.3e-102 339.9 0.0 2.0 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KND87734.1 - 0.00095 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KND87734.1 - 0.0011 18.8 2.6 0.46 10.2 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KND87734.1 - 0.0084 15.3 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KND87734.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KND87734.1 - 0.056 14.2 3.3 0.21 12.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KND87734.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND87734.1 - 0.081 13.0 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3653 PF12375.3 KND87734.1 - 0.73 10.0 2.9 15 5.9 1.1 2.8 2 1 0 2 2 2 0 Phage protein QRPTase_C PF01729.14 KND87735.1 - 7.4e-55 185.0 0.3 9.2e-55 184.7 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KND87735.1 - 4.1e-22 77.8 0.1 1.5e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 KND87735.1 - 0.003 17.1 0.1 0.0044 16.5 0.1 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Cu_amine_oxid PF01179.15 KND87736.1 - 3e-125 418.1 0.0 1.2e-119 399.7 0.0 2.0 2 0 0 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KND87736.1 - 2.8e-09 36.9 0.0 5.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KND87736.1 - 5.9e-07 29.4 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Pkinase PF00069.20 KND87737.1 - 5.1e-59 199.5 0.0 7.3e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87737.1 - 1.9e-37 128.7 0.0 5.3e-37 127.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND87737.1 - 3.6e-05 22.8 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 KND87737.1 - 0.0061 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 APH PF01636.18 KND87737.1 - 0.12 12.1 5.0 0.31 10.7 0.1 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.4 KND87737.1 - 0.45 8.7 4.3 0.81 7.8 3.0 1.4 1 0 0 1 1 1 0 Transmembrane protein BTB PF00651.26 KND87738.1 - 7.3e-25 87.1 0.0 2e-12 47.0 0.2 3.0 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.25 KND87738.1 - 1.2e-08 34.3 1.2 3.4e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KND87738.1 - 1.2e-08 35.1 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND87738.1 - 2.9e-08 34.0 0.1 9.1e-08 32.4 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND87738.1 - 2e-06 27.8 0.0 4e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND87738.1 - 0.00016 21.5 0.1 0.0087 16.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Pox_P4B PF03292.9 KND87738.1 - 0.0044 15.0 0.0 0.0062 14.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus P4B major core protein Choline_kinase PF01633.15 KND87739.1 - 3.9e-59 199.7 0.5 6.6e-59 199.0 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KND87739.1 - 1.4e-18 66.0 0.0 3e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KND87739.1 - 2.8e-08 33.7 0.6 2.8e-08 33.7 0.4 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RNA_capsid PF03035.9 KND87739.1 - 1.2 8.8 3.9 1.3 8.8 1.7 1.7 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein SCO1-SenC PF02630.9 KND87740.1 - 1.5e-56 190.7 0.0 2.3e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Hydrolase_6 PF13344.1 KND87740.1 - 1.7e-19 69.5 0.0 4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND87740.1 - 1.4e-14 53.5 0.2 5.5e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KND87740.1 - 9.7e-08 32.6 0.0 0.0003 21.2 0.0 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND87740.1 - 0.0075 16.5 0.1 1.5 8.9 0.0 3.5 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.16 KND87740.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.1 KND87740.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like PHD PF00628.24 KND87741.1 - 3.7e-11 42.5 12.0 9.1e-11 41.2 8.3 1.7 1 0 0 1 1 1 1 PHD-finger Herpes_DNAp_acc PF04929.7 KND87741.1 - 4 6.3 5.0 5.8 5.7 3.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor WD40 PF00400.27 KND87742.1 - 2.1e-26 90.7 8.2 8.1e-07 28.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat GDC-P PF02347.11 KND87743.1 - 7.5e-159 528.9 0.0 1.6e-144 481.7 0.0 3.2 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KND87743.1 - 5.8e-05 22.3 0.0 0.00014 21.1 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Tom5 PF10642.4 KND87744.1 - 2.9e-19 68.4 1.0 3e-19 68.4 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 KND87745.1 - 3.1e-43 146.8 3.2 3.5e-43 146.6 0.5 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.7 KND87745.1 - 0.084 12.6 0.3 0.83 9.4 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40_alt PF14077.1 KND87745.1 - 0.1 12.2 0.7 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif YliH PF10799.3 KND87745.1 - 0.1 12.2 0.2 0.34 10.5 0.0 1.9 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) HOOK PF05622.7 KND87745.1 - 0.22 9.3 6.8 0.51 8.0 4.6 1.6 1 1 0 1 1 1 0 HOOK protein DUF4618 PF15397.1 KND87745.1 - 0.27 10.5 2.7 2 7.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Nucleoporin_FG PF13634.1 KND87745.1 - 0.42 10.8 15.0 0.65 10.2 10.4 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Cep57_MT_bd PF06657.8 KND87745.1 - 1.3 9.0 5.2 3 7.8 0.1 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 bZIP_2 PF07716.10 KND87745.1 - 2 8.2 12.3 1.3 8.8 0.3 3.9 3 1 0 4 4 4 0 Basic region leucine zipper CENP-F_leu_zip PF10473.4 KND87745.1 - 2.1 8.2 11.0 3.1 7.6 0.4 3.2 1 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 KND87745.1 - 2.9 6.2 6.1 5 5.4 4.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 KND87745.1 - 4.9 7.6 8.7 14 6.2 0.1 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 KND87745.1 - 6.2 6.8 8.8 4.3 7.3 0.0 3.4 4 1 1 5 5 5 0 bZIP transcription factor Formyl_trans_N PF00551.14 KND87747.1 - 2.3e-31 108.7 0.2 2.9e-30 105.1 0.1 2.0 1 1 0 1 1 1 1 Formyl transferase Abhydrolase_2 PF02230.11 KND87748.1 - 4.4e-49 166.8 0.0 5e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KND87748.1 - 4.3e-12 45.9 0.0 5.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND87748.1 - 1.1e-11 45.1 0.5 2.6e-11 43.8 0.2 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 KND87748.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KND87748.1 - 0.0051 16.3 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KND87748.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 KND87748.1 - 0.065 12.7 1.1 0.094 12.2 0.0 1.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KND87748.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RTC PF01137.16 KND87749.1 - 6.3e-44 149.4 0.0 8.5e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Methyltransf_18 PF12847.2 KND87750.1 - 1.4e-10 41.7 0.1 2.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND87750.1 - 3.8e-09 36.4 0.0 5.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87750.1 - 2.9e-08 34.0 0.0 4.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87750.1 - 6.6e-07 29.7 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87750.1 - 5.6e-06 26.0 0.0 7.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND87750.1 - 2.2e-05 24.7 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND87750.1 - 0.00012 22.0 0.0 0.00014 21.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND87750.1 - 0.00052 19.1 0.0 0.00078 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KND87750.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KND87750.1 - 0.0098 15.5 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 KND87750.1 - 0.023 14.0 0.0 0.043 13.2 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KND87750.1 - 0.034 12.8 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF1237 PF06824.6 KND87751.1 - 7e-139 463.0 0.0 8.1e-139 462.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) TPR_11 PF13414.1 KND87752.1 - 2.5e-13 49.4 2.0 2.1e-07 30.4 0.0 4.7 3 2 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 KND87752.1 - 7.2e-13 47.3 7.3 2e-05 24.1 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND87752.1 - 1.9e-09 36.7 0.3 0.00045 19.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND87752.1 - 3.6e-08 33.2 0.6 0.58 10.1 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KND87752.1 - 8.9e-07 29.1 4.4 1.7 9.0 0.0 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND87752.1 - 1.7e-05 25.3 26.8 0.038 14.6 0.0 7.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND87752.1 - 0.00011 21.7 1.9 0.63 9.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND87752.1 - 0.00093 18.8 0.1 7.6 6.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND87752.1 - 0.0019 18.2 1.3 24 5.4 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND87752.1 - 0.057 14.0 29.8 7.2 7.5 0.0 8.6 8 2 2 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND87752.1 - 0.085 13.3 0.7 69 4.2 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND87752.1 - 0.1 12.4 6.1 6.8 6.6 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat IMD PF08397.6 KND87753.1 - 0.31 10.3 13.3 0.029 13.6 2.4 2.9 2 1 0 2 2 2 0 IRSp53/MIM homology domain DUF4557 PF15101.1 KND87753.1 - 0.47 10.2 10.5 0.033 14.0 3.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) ABC_tran PF00005.22 KND87755.1 - 1e-44 152.1 0.0 3e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND87755.1 - 3.2e-41 141.5 19.3 1.7e-26 93.2 6.2 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region FtsK_SpoIIIE PF01580.13 KND87755.1 - 2.1e-06 27.3 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KND87755.1 - 2.2e-06 27.7 0.9 0.064 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KND87755.1 - 4e-06 26.2 0.8 0.068 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KND87755.1 - 1.1e-05 24.8 0.7 0.05 12.8 0.1 3.8 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND87755.1 - 2e-05 24.7 0.1 0.47 10.3 0.0 4.0 3 1 1 4 4 4 1 AAA domain DUF258 PF03193.11 KND87755.1 - 2.6e-05 23.4 0.1 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KND87755.1 - 5.6e-05 23.5 0.2 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND87755.1 - 7.8e-05 22.1 0.0 0.093 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KND87755.1 - 0.00021 22.0 0.0 0.042 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KND87755.1 - 0.00025 20.9 1.3 0.0048 16.7 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KND87755.1 - 0.00041 20.2 0.3 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 KND87755.1 - 0.00049 19.0 0.0 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 KND87755.1 - 0.00073 20.0 0.4 1.6 9.2 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 KND87755.1 - 0.00087 18.8 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 KND87755.1 - 0.0012 18.5 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KND87755.1 - 0.0016 18.5 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KND87755.1 - 0.0051 16.7 0.0 2.9 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND87755.1 - 0.018 15.3 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KND87755.1 - 0.023 14.5 2.9 0.71 9.6 0.1 2.7 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 KND87755.1 - 0.048 13.3 3.3 2.7 7.6 0.6 2.9 2 1 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KND87755.1 - 0.052 12.6 0.5 7.3 5.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 KND87755.1 - 0.059 12.9 0.3 3.7 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 KND87755.1 - 0.059 12.6 0.6 3.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AIG1 PF04548.11 KND87755.1 - 0.15 11.1 0.2 11 4.9 0.2 2.3 2 0 0 2 2 2 0 AIG1 family DUF2075 PF09848.4 KND87755.1 - 0.54 9.1 0.4 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 KND87755.1 - 0.62 9.0 0.0 1.1 8.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 KND87755.1 - 0.81 8.5 2.0 6 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TPR_12 PF13424.1 KND87757.1 - 3.2e-48 161.5 0.3 4.1e-15 55.4 0.0 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KND87757.1 - 6.3e-48 159.4 4.9 6.5e-10 38.6 0.0 7.1 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KND87757.1 - 2.5e-13 48.7 2.3 0.045 13.5 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KND87757.1 - 1.5e-10 40.1 2.1 0.24 11.3 0.1 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KND87757.1 - 1.6e-09 37.2 0.0 7.8e-06 25.4 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 KND87757.1 - 1.7e-09 37.1 0.8 0.39 11.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND87757.1 - 7.3e-08 31.7 1.8 0.043 13.4 0.1 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND87757.1 - 7.4e-07 29.6 0.0 0.00032 21.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KND87757.1 - 1.9e-05 24.8 1.5 7.1 7.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND87757.1 - 0.00011 22.4 3.7 9.9 7.1 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND87757.1 - 0.00014 22.1 0.7 0.33 11.3 0.0 3.5 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KND87757.1 - 0.00088 19.4 1.2 4.4 8.0 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND87757.1 - 0.0015 18.2 2.8 5 7.1 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 KND87757.1 - 0.0016 18.5 0.0 0.0048 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KND87757.1 - 0.0027 16.6 0.0 0.0057 15.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KND87757.1 - 0.0053 16.8 0.0 0.07 13.2 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KND87757.1 - 0.0077 16.1 0.5 14 5.9 0.0 4.0 4 0 0 4 4 3 0 PPR repeat Abhydrolase_6 PF12697.2 KND87757.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2664 PF10867.3 KND87757.1 - 0.026 15.1 0.4 1.8 9.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) DUF4033 PF13225.1 KND87758.1 - 0.016 14.8 0.4 0.03 13.9 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4033) DUF3435 PF11917.3 KND87759.1 - 1.2e-54 185.6 0.0 6.3e-41 140.4 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3435) LRV PF01816.12 KND87759.1 - 0.014 15.5 0.2 0.26 11.5 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeat variant Glyco_hydro_18 PF00704.23 KND87760.1 - 2.5e-34 119.2 2.8 4e-34 118.5 0.1 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Antimicrobial17 PF08129.6 KND87760.1 - 0.0015 18.2 0.2 0.19 11.5 0.0 3.4 3 0 0 3 3 3 1 Alpha/beta enterocin family DUF3142 PF11340.3 KND87760.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) FHA PF00498.21 KND87761.1 - 1.6e-17 63.3 0.2 9e-17 60.9 0.0 2.4 2 0 0 2 2 2 1 FHA domain TBPIP PF07106.8 KND87761.1 - 0.46 10.0 10.5 0.26 10.8 0.9 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps51 PF08700.6 KND87761.1 - 2.1 8.2 9.0 6.6 6.6 0.1 3.1 3 0 0 3 3 3 0 Vps51/Vps67 Prefoldin_2 PF01920.15 KND87761.1 - 2.4 7.9 9.4 2.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Prefoldin subunit Sec34 PF04136.10 KND87761.1 - 6.6 6.4 6.0 25 4.5 0.2 2.2 2 0 0 2 2 2 0 Sec34-like family Romo1 PF10247.4 KND87762.1 - 4.9e-16 58.6 11.3 2.9e-14 52.9 7.8 2.4 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SIR2 PF02146.12 KND87763.1 - 6.6e-55 185.5 0.0 1e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.18 KND87764.1 - 2.6e-17 62.6 0.6 4.1e-17 61.9 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND87764.1 - 0.0051 16.9 0.0 0.015 15.4 0.0 1.8 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Decorin_bind PF02352.10 KND87764.1 - 0.044 13.7 0.3 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Decorin binding protein adh_short PF00106.20 KND87766.1 - 2.4e-27 95.8 0.2 3.4e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND87766.1 - 1.2e-13 51.4 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND87766.1 - 2.8e-10 40.1 0.2 4.3e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND87766.1 - 0.0038 17.2 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 KND87766.1 - 0.043 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 KND87766.1 - 0.045 13.1 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family S-methyl_trans PF02574.11 KND87767.1 - 2.8e-13 49.8 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase LysM PF01476.15 KND87771.1 - 2.2e-08 33.8 0.0 0.0039 17.0 0.0 2.7 2 0 0 2 2 2 2 LysM domain Glyco_hydro_18 PF00704.23 KND87771.1 - 3.3e-05 23.5 0.9 4.3e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KND87771.1 - 4.3e-05 23.4 1.9 4.3e-05 23.4 1.3 3.3 4 0 0 4 4 4 1 Chitin recognition protein Thioredox_DsbH PF03190.10 KND87773.1 - 3e-59 199.4 0.0 4.8e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KND87773.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like DLIC PF05783.6 KND87774.1 - 3.5e-28 98.5 0.0 2.7e-26 92.2 0.0 2.8 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) CAP PF00188.21 KND87775.1 - 2.6e-22 79.6 4.4 3.6e-22 79.1 3.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.8 KND87776.1 - 6.1e-08 32.3 13.6 1.7e-06 27.7 2.6 2.7 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KND87776.1 - 0.00045 19.9 10.9 0.054 13.2 0.4 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KND87776.1 - 0.12 12.4 8.8 0.61 10.1 5.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 TMEM154 PF15102.1 KND87777.1 - 0.0076 15.9 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 KND87777.1 - 0.077 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Herpes_gE PF02480.11 KND87777.1 - 0.091 11.0 0.2 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E tRNA_anti-like PF12869.2 KND87777.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like Syndecan PF01034.15 KND87777.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain PCI PF01399.22 KND87778.1 - 1e-22 80.3 0.2 4.8e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain Asp_Glu_race_2 PF14669.1 KND87778.1 - 0.00044 19.6 3.6 0.033 13.5 0.4 2.3 1 1 1 2 2 2 2 Putative aspartate racemase EST1_DNA_bind PF10373.4 KND87778.1 - 0.3 10.2 4.2 0.64 9.1 0.0 2.6 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain Caldesmon PF02029.10 KND87778.1 - 1.6 7.0 12.1 0.31 9.4 5.2 1.9 2 0 0 2 2 2 0 Caldesmon FSH1 PF03959.8 KND87779.1 - 4.3e-52 176.6 0.0 4.1e-51 173.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KND87779.1 - 0.0041 16.8 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND87779.1 - 0.0084 16.0 1.1 0.045 13.6 0.7 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family ATP-synt_J PF04911.7 KND87780.1 - 6.4e-15 54.3 0.1 1.3e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.8 KND87781.1 - 2.1e-39 133.6 0.6 1.5e-28 98.7 0.1 2.6 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.4 KND87782.1 - 2e-60 204.2 0.0 2.3e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 KND87783.1 - 1e-30 106.2 0.0 1.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KND87783.1 - 1.6e-21 75.6 0.0 2.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Alba DUF2514 PF10721.4 KND87783.1 - 0.22 11.1 3.3 0.25 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Chorion_2 PF03964.10 KND87783.1 - 0.58 10.7 3.9 0.27 11.8 0.7 1.9 2 0 0 2 2 2 0 Chorion family 2 DUF3237 PF11578.3 KND87784.1 - 1.3e-12 47.2 0.0 1.6e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) OPT PF03169.10 KND87786.1 - 1.3e-159 532.5 42.3 1.5e-159 532.4 29.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.19 KND87787.1 - 2.8e-58 197.5 33.1 6.9e-39 133.6 9.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KND87787.1 - 6.3e-08 31.7 39.1 9.4e-05 21.2 9.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KND87788.1 - 5.2e-26 91.1 39.9 2.8e-25 88.7 24.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily M20_dimer PF07687.9 KND87789.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase dimerisation domain DUF724 PF05266.9 KND87789.1 - 0.15 11.6 0.1 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAD_binding_4 PF01565.18 KND87791.1 - 3.5e-34 117.2 5.4 6.3e-34 116.4 3.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND87791.1 - 5.3e-09 35.8 0.0 4.6e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like ATG22 PF11700.3 KND87792.1 - 2.1e-121 405.7 23.6 2.4e-121 405.5 16.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KND87792.1 - 6.8e-05 21.7 37.3 0.00084 18.1 3.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily ADH_zinc_N PF00107.21 KND87794.1 - 1.7e-21 76.1 0.0 2.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND87794.1 - 1.2e-06 29.4 0.0 2.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF469 PF04320.9 KND87794.1 - 0.14 12.9 0.0 7.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein with unknown function (DUF469) p450 PF00067.17 KND87796.1 - 8.4e-16 57.5 0.0 1.1e-06 27.4 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 NAD_binding_10 PF13460.1 KND87797.1 - 3.4e-19 69.5 0.0 5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND87797.1 - 2.7e-13 49.9 0.0 2.8e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KND87797.1 - 0.0004 19.3 0.0 0.022 13.6 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 KND87797.1 - 0.039 13.2 0.0 2.9 7.1 0.1 2.2 2 0 0 2 2 2 0 NmrA-like family NAD_binding_4 PF07993.7 KND87797.1 - 0.042 12.7 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 KND87797.1 - 0.39 10.6 2.7 0.27 11.1 0.2 2.0 2 1 0 2 2 2 0 short chain dehydrogenase Alginate_lyase2 PF08787.6 KND87798.1 - 5.4e-44 150.6 0.0 6.2e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase DUF3762 PF12591.3 KND87799.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) PS_Dcarbxylase PF02666.10 KND87800.1 - 2.2e-49 167.5 0.0 2.7e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Baculo_8kDa PF06096.6 KND87800.1 - 0.0085 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Baculoviridae 8.2 KDa protein EBP PF05241.7 KND87801.1 - 1.3e-57 193.9 3.2 1.6e-57 193.6 2.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein ERG4_ERG24 PF01222.12 KND87802.1 - 2.5e-150 500.8 3.1 2.8e-150 500.6 2.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KND87802.1 - 0.0016 17.7 0.2 0.0016 17.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PRA-PH PF01503.12 KND87803.1 - 0.076 13.2 0.5 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase CcmD PF04995.9 KND87803.1 - 7.7 6.3 7.1 17 5.2 0.2 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) PRP38 PF03371.10 KND87804.1 - 1.3e-60 203.9 0.0 1.7e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Amidase PF01425.16 KND87805.1 - 2.1e-109 366.3 0.1 2.8e-109 365.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Peptidase_M17_N PF02789.12 KND87805.1 - 0.12 12.1 0.5 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain SIP1 PF04938.7 KND87806.1 - 5.5e-05 22.6 0.3 0.35 10.1 0.0 3.2 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Utp14 PF04615.8 KND87806.1 - 0.91 7.6 13.0 1.4 7.0 9.0 1.1 1 0 0 1 1 1 0 Utp14 protein RNR_inhib PF08591.5 KND87807.1 - 2.9e-19 69.7 0.1 1.1e-18 67.9 0.0 2.0 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.12 KND87808.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KND87808.1 - 0.013 15.3 1.4 0.015 15.1 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 KND87808.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.11 KND87809.1 - 1.2e-10 40.5 0.0 1.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KND87809.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin LRR_4 PF12799.2 KND87810.1 - 7.1e-13 47.8 6.4 2.2e-09 36.7 1.7 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND87810.1 - 2.9e-09 36.5 1.1 2.9e-09 36.5 0.8 2.7 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KND87810.1 - 4.7e-07 28.9 2.1 0.022 14.7 0.0 4.3 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KND87810.1 - 2.2e-05 23.9 5.6 0.14 12.4 0.2 4.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KND87810.1 - 0.15 12.2 3.0 12 6.2 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeat COX16 PF14138.1 KND87811.1 - 2.9e-30 104.2 0.1 5e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 adh_short PF00106.20 KND87811.1 - 1.5e-08 34.6 0.0 2.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KND87811.1 - 0.004 16.8 0.0 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 KR domain TPR_12 PF13424.1 KND87813.1 - 0.14 12.0 0.0 1 9.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KND87814.1 - 3.9e-18 65.6 0.0 1.2e-17 63.9 0.0 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain ThiF PF00899.16 KND87815.1 - 4.4e-33 113.9 0.0 9.1e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 KND87815.1 - 0.0035 16.4 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 NAD_binding_7 PF13241.1 KND87815.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 KND87815.1 - 0.022 13.7 0.2 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 KND87815.1 - 0.034 14.1 0.9 0.08 12.9 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 KND87815.1 - 0.095 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.14 KND87815.1 - 0.14 10.7 0.2 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C2H2 PF00096.21 KND87816.1 - 6.6e-08 32.4 16.2 0.00038 20.6 1.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND87816.1 - 5.6e-07 29.5 12.4 1e-06 28.7 0.8 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND87816.1 - 3e-05 24.0 10.6 0.0092 16.2 1.2 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KND87816.1 - 0.011 15.9 3.4 0.037 14.2 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND87816.1 - 0.062 13.4 6.8 0.065 13.3 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KND87816.1 - 2.3 8.0 7.7 10 5.9 0.5 2.5 1 1 1 2 2 2 0 BED zinc finger Ead_Ea22 PF13935.1 KND87817.1 - 0.024 14.9 0.1 0.033 14.5 0.1 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein Pox_A_type_inc PF04508.7 KND87817.1 - 0.058 13.1 0.8 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2365 PF10157.4 KND87817.1 - 0.059 13.2 0.1 0.081 12.8 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DASH_Spc19 PF08287.6 KND87819.1 - 1.3e-38 132.0 2.3 2.4e-38 131.1 1.6 1.5 1 1 0 1 1 1 1 Spc19 THOC7 PF05615.8 KND87819.1 - 0.091 13.0 3.6 0.11 12.7 2.4 1.3 1 1 0 1 1 1 0 Tho complex subunit 7 DUF1843 PF08898.5 KND87819.1 - 6.7 6.8 7.5 33 4.6 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) SH3_1 PF00018.23 KND87820.1 - 1.8e-09 36.8 0.1 3.1e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KND87820.1 - 9.9e-07 28.1 0.0 2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KND87820.1 - 1.2e-06 27.9 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ABC2_membrane_2 PF12679.2 KND87820.1 - 0.52 9.1 7.0 0.69 8.7 4.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 7TMR-DISM_7TM PF07695.6 KND87820.1 - 0.55 9.8 11.6 0.75 9.4 8.1 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling YwiC PF14256.1 KND87820.1 - 0.85 9.7 8.5 1.9 8.6 5.9 1.6 1 1 0 1 1 1 0 YwiC-like protein DUF3040 PF11239.3 KND87820.1 - 3.2 7.8 5.4 5.8 7.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF4131 PF13567.1 KND87820.1 - 9.9 5.5 8.0 5.4 6.3 2.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Copper-fist PF00649.13 KND87821.1 - 4.9e-16 57.6 1.7 4.9e-16 57.6 1.2 2.4 1 1 1 2 2 2 1 Copper fist DNA binding domain Ank_2 PF12796.2 KND87822.1 - 3.8e-109 357.2 4.9 1.8e-22 79.4 0.0 8.6 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KND87822.1 - 5.3e-98 316.3 0.0 1.1e-08 34.4 0.0 14.8 14 1 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.1 KND87822.1 - 2.5e-76 243.9 0.0 3.3e-05 23.6 0.0 15.9 16 0 0 16 16 16 12 Ankyrin repeat Ank_4 PF13637.1 KND87822.1 - 7.7e-71 233.3 5.3 1.2e-10 41.5 0.1 11.8 4 1 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND87822.1 - 3.7e-66 217.6 4.4 4e-11 42.7 0.1 9.9 6 2 2 10 10 10 7 Ankyrin repeats (many copies) NACHT PF05729.7 KND87822.1 - 3.1e-10 39.9 0.1 2.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KND87822.1 - 5e-05 23.4 0.0 0.00028 21.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KND87822.1 - 0.023 14.8 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S16 PF00886.14 KND87823.1 - 2.4e-18 65.6 0.1 2.7e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 KND87824.1 - 1.8e-23 82.9 0.0 7.4e-23 80.9 0.0 2.0 2 1 0 2 2 2 1 YjeF-related protein N-terminus ABC_sub_bind PF04392.7 KND87824.1 - 0.083 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein Aa_trans PF01490.13 KND87826.1 - 2.3e-69 233.8 8.6 6.1e-42 143.5 5.7 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KND87826.1 - 0.00068 18.5 5.9 0.00068 18.5 4.1 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family YfhO PF09586.5 KND87826.1 - 0.04 11.9 0.4 0.09 10.7 0.4 1.4 2 0 0 2 2 2 0 Bacterial membrane protein YfhO CM_2 PF01817.16 KND87829.1 - 2.6e-06 27.4 0.0 9.2e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 Chorismate mutase type II BCIP PF13862.1 KND87830.1 - 3e-64 216.1 0.2 3.9e-64 215.7 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF2597 PF10772.4 KND87830.1 - 0.0017 18.2 0.2 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2597) CENP-Q PF13094.1 KND87832.1 - 0.0006 19.8 2.3 0.0006 19.8 1.6 3.4 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.4 KND87832.1 - 0.016 15.3 3.2 0.2 11.8 0.4 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3086 PF11285.3 KND87832.1 - 0.036 12.8 1.6 0.063 12.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Sec20 PF03908.8 KND87832.1 - 0.037 13.7 1.6 0.054 13.1 0.1 2.0 2 0 0 2 2 2 0 Sec20 Phage_GP20 PF06810.6 KND87832.1 - 0.051 13.0 3.4 0.058 12.8 0.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 KND87832.1 - 0.055 13.2 11.0 0.82 9.5 2.5 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Leu_zip PF15294.1 KND87832.1 - 0.06 12.4 8.2 0.01 14.9 2.6 1.9 2 0 0 2 2 2 0 Leucine zipper DUF4259 PF14078.1 KND87832.1 - 0.11 12.9 0.3 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) bZIP_1 PF00170.16 KND87832.1 - 0.31 11.0 10.9 0.64 10.0 0.4 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 KND87832.1 - 0.38 11.1 9.0 7.1 7.0 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Matrilin_ccoil PF10393.4 KND87832.1 - 0.49 9.7 3.7 0.89 8.9 0.0 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Ax_dynein_light PF10211.4 KND87832.1 - 0.96 9.2 11.4 9.7 5.9 4.3 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4446 PF14584.1 KND87832.1 - 1.5 8.6 7.8 1.4 8.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4201 PF13870.1 KND87832.1 - 2.4 7.5 12.2 7.8 5.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.1 KND87832.1 - 3.6 6.7 12.0 1.6 7.9 3.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KND87832.1 - 4.8 6.7 5.9 3.5 7.1 1.4 2.1 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 KND87832.1 - 5.9 6.4 11.9 4.1 6.9 4.6 2.4 2 0 0 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.15 KND87832.1 - 8.6 6.1 10.7 4 7.2 1.8 2.6 3 0 0 3 3 2 0 Prefoldin subunit MFS_1 PF07690.11 KND87833.1 - 2.8e-28 98.6 22.0 1.7e-25 89.5 12.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DnaA_N PF11638.3 KND87833.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 DnaA N-terminal domain CDC37_N PF03234.9 KND87837.1 - 4.8e-48 163.8 4.7 4.8e-48 163.8 3.3 2.7 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding WD40 PF00400.27 KND87837.1 - 4.7e-35 118.2 6.9 5.6e-09 35.5 0.3 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat CDC37_M PF08565.6 KND87837.1 - 2.9e-33 114.7 3.4 8.3e-33 113.2 1.0 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain Cupin_8 PF13621.1 KND87837.1 - 1.5e-29 103.2 0.0 3.7e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain CDC37_C PF08564.5 KND87837.1 - 1.1e-15 57.2 0.0 1.1e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Cdc37 C terminal domain Nup160 PF11715.3 KND87837.1 - 2.2e-06 26.1 7.3 0.038 12.1 0.1 4.3 2 2 3 5 5 5 2 Nucleoporin Nup120/160 JmjC PF02373.17 KND87837.1 - 3.5e-05 24.0 0.3 0.00014 22.1 0.0 2.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KND87837.1 - 0.0001 21.6 0.0 0.0057 15.9 0.0 3.1 3 0 0 3 3 3 1 Cupin superfamily protein Cupin_2 PF07883.6 KND87837.1 - 0.092 12.2 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain APH PF01636.18 KND87838.1 - 0.0002 21.1 2.7 0.00048 19.9 1.4 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Iso_dh PF00180.15 KND87839.1 - 1.3e-95 320.3 0.0 1.7e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 KND87840.1 - 2.5e-36 125.1 0.0 6e-35 120.6 0.0 2.6 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 KND87840.1 - 0.00025 20.8 2.7 0.0006 19.6 0.0 3.0 3 0 0 3 3 3 1 Vps51/Vps67 MFS_1 PF07690.11 KND87841.1 - 6.6e-46 156.6 34.2 6.6e-46 156.6 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KND87841.1 - 0.053 11.5 3.7 0.17 9.8 2.6 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Transglut_core PF01841.14 KND87842.1 - 3.1e-10 40.2 0.0 6.9e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily LRR_4 PF12799.2 KND87843.1 - 0.0014 18.2 1.1 3 7.5 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Spc7 PF08317.6 KND87843.1 - 0.0036 16.0 0.0 0.0061 15.2 0.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein F-box-like PF12937.2 KND87843.1 - 0.0043 16.7 0.1 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2968 PF11180.3 KND87843.1 - 0.016 14.6 0.5 0.037 13.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Seryl_tRNA_N PF02403.17 KND87843.1 - 0.035 14.1 2.4 3.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain F-box-like_2 PF13013.1 KND87843.1 - 0.035 13.8 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 KND87843.1 - 0.12 12.0 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.1 KND87843.1 - 0.35 10.6 3.7 31 4.4 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KND87844.1 - 0.0072 16.0 0.8 0.023 14.4 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND87844.1 - 0.021 14.4 0.8 0.046 13.3 0.6 1.5 1 0 0 1 1 1 0 F-box domain E1_DerP2_DerF2 PF02221.10 KND87847.1 - 2.3e-21 76.4 0.5 1.3e-20 74.0 0.3 1.9 1 1 0 1 1 1 1 ML domain TRP_N PF14558.1 KND87847.1 - 0.00019 21.4 0.1 0.0015 18.6 0.1 2.1 1 1 0 1 1 1 1 ML-like domain PHD PF00628.24 KND87848.1 - 2.1e-08 33.7 8.7 5.1e-08 32.4 6.1 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 KND87848.1 - 6.1e-05 23.3 0.0 6.1e-05 23.3 0.0 2.5 3 1 0 3 3 3 1 SET domain Glycos_transf_4 PF00953.16 KND87849.1 - 1.3e-28 99.7 9.4 1.3e-28 99.7 6.5 1.9 2 1 1 3 3 3 1 Glycosyl transferase family 4 DUF2107 PF09880.4 KND87849.1 - 0.48 10.3 5.4 1.8 8.4 0.2 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2107) FAD_binding_4 PF01565.18 KND87850.1 - 6e-23 80.8 0.7 1.9e-22 79.2 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KND87850.1 - 0.0094 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Mlf1IP PF10248.4 KND87850.1 - 0.096 12.2 0.3 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF3328 PF11807.3 KND87851.1 - 1.3e-54 185.1 0.0 1.7e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.1 KND87852.1 - 3.1e-17 62.7 0.0 6.2e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87852.1 - 6.2e-06 26.6 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87852.1 - 0.00061 20.2 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87852.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KND87852.1 - 0.024 15.1 0.0 0.12 12.9 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 KND87852.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DnaJ PF00226.26 KND87853.1 - 0.0021 17.7 0.0 0.0078 15.9 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain SMC_Nse1 PF07574.8 KND87854.1 - 2.5e-38 131.7 0.0 3.4e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KND87854.1 - 2.5e-09 36.9 7.0 3.8e-09 36.3 4.9 1.3 1 0 0 1 1 1 1 RING-like domain HTH_27 PF13463.1 KND87854.1 - 0.05 13.9 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain zf-HC5HC2H PF13771.1 KND87854.1 - 0.47 10.6 6.7 0.22 11.6 1.3 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KND87854.1 - 0.64 10.0 6.0 0.53 10.3 1.2 2.3 1 1 1 2 2 2 0 PHD-zinc-finger like domain Clr2 PF10383.4 KND87855.1 - 1.9e-10 40.8 0.0 5.9e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 SPRY PF00622.23 KND87856.1 - 2.2e-09 37.4 0.0 2e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 SPRY domain MLANA PF14991.1 KND87857.1 - 0.042 13.8 0.0 4.9 7.1 0.0 2.6 3 0 0 3 3 3 0 Protein melan-A DUF2752 PF10825.3 KND87857.1 - 0.15 12.0 1.2 0.25 11.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DUF4381 PF14316.1 KND87857.1 - 0.17 11.9 0.8 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) HTH_Tnp_Tc5 PF03221.11 KND87858.1 - 1.2e-16 60.2 1.4 5e-08 32.6 0.1 4.5 4 1 0 4 4 4 3 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 KND87858.1 - 2.7e-14 52.5 1.4 6.8e-14 51.2 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KND87858.1 - 6.8e-06 25.6 0.5 1.6e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KND87858.1 - 0.014 15.6 4.2 0.014 15.6 2.9 5.2 6 0 0 6 6 6 0 C2H2-type zinc finger ECH PF00378.15 KND87858.1 - 0.047 12.7 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family zf-C2H2 PF00096.21 KND87858.1 - 0.067 13.5 19.9 0.033 14.5 2.6 4.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type mRNA_stabil PF13929.1 KND87858.1 - 0.26 10.2 0.0 0.42 9.5 0.0 1.2 1 0 0 1 1 1 0 mRNA stabilisation GATA PF00320.22 KND87860.1 - 2.1e-31 106.9 17.9 3.5e-17 61.4 2.3 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KND87860.1 - 2.4e-06 26.7 2.5 0.01 15.1 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 KND87860.1 - 0.0003 20.5 1.6 0.1 12.3 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 KND87860.1 - 0.00067 18.7 5.6 0.36 10.1 0.2 2.9 2 1 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KND87860.1 - 0.0011 18.5 5.4 0.058 13.0 0.5 2.9 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 KND87860.1 - 0.014 15.3 4.0 1.2 9.1 0.1 2.9 3 0 0 3 3 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 KND87860.1 - 0.045 13.3 0.5 0.045 13.3 0.3 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Auto_anti-p27 PF06677.7 KND87860.1 - 0.24 11.1 3.8 8.4 6.2 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.2 KND87860.1 - 0.33 10.7 17.1 0.25 11.1 0.9 3.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KND87860.1 - 0.76 9.6 6.8 1.7 8.5 0.8 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L32p PF01783.18 KND87860.1 - 0.94 9.7 9.5 3.8 7.7 1.2 4.0 2 2 0 2 2 2 0 Ribosomal L32p protein family zf-C2H2_3 PF13878.1 KND87860.1 - 0.99 9.0 10.5 5.4 6.6 0.3 4.2 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO eIF-5_eIF-2B PF01873.12 KND87860.1 - 1.2 8.8 5.3 6.3 6.4 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 HypA PF01155.14 KND87860.1 - 1.6 8.4 6.8 3.5 7.3 0.1 2.9 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 KND87861.1 - 1.4e-28 99.6 27.3 1.4e-28 99.6 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSase_sm_chain PF00988.17 KND87866.1 - 1.5e-46 157.1 0.0 3e-46 156.1 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KND87866.1 - 2.2e-45 154.5 0.0 3e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KND87866.1 - 2.4e-06 27.1 0.1 0.00019 20.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 SAP PF02037.22 KND87867.1 - 7.6e-13 47.6 0.4 1.2e-12 46.9 0.3 1.4 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 KND87867.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavodoxin_1 PF00258.20 KND87868.1 - 1.7e-29 102.6 0.0 2.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KND87868.1 - 2.3e-29 102.3 0.0 4.8e-29 101.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KND87868.1 - 1.7e-13 51.1 0.0 3.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 KND87868.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.2 KND87868.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.9 2 1 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 KND87869.1 - 8.1e-30 102.2 0.1 4.4e-14 51.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND87869.1 - 5e-23 80.8 0.0 2.6e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND87869.1 - 2.2e-07 30.5 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SSFA2_C PF14723.1 KND87869.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus API5 PF05918.6 KND87869.1 - 0.41 9.0 2.8 0.6 8.5 2.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ArfGap PF01412.13 KND87870.1 - 1.4e-32 111.9 0.3 2.9e-32 110.9 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ETF PF01012.16 KND87871.1 - 5.7e-38 130.2 0.4 7.7e-38 129.7 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain F-box-like PF12937.2 KND87872.1 - 3.9e-09 36.0 0.0 7.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND87872.1 - 4.9e-07 29.2 0.0 1.8e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 KND87872.1 - 0.002 17.5 3.8 0.002 17.5 2.6 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif Asp PF00026.18 KND87875.1 - 2e-07 30.5 0.0 3.5e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease NicO PF03824.11 KND87875.1 - 0.0003 20.2 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 High-affinity nickel-transport protein Herpes_gE PF02480.11 KND87875.1 - 0.037 12.3 0.0 0.058 11.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KND87875.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP-synt_C PF00137.16 KND87876.1 - 5.4e-27 93.4 20.1 4.1e-17 61.8 2.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 KND87876.1 - 0.43 10.8 2.6 2.4 8.4 0.0 2.6 2 1 1 3 3 3 0 G0/G1 switch protein 2 Cation_efflux PF01545.16 KND87876.1 - 5.3 6.0 9.9 0.83 8.6 0.1 2.5 1 1 1 2 2 2 0 Cation efflux family RNase_P_Rpp14 PF01900.14 KND87878.1 - 2.9e-35 120.4 0.0 4e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family MoCF_biosynth PF00994.19 KND87879.1 - 4.7e-54 181.7 0.2 1.3e-29 102.4 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KND87879.1 - 3.3e-34 117.5 3.8 5.9e-34 116.7 2.6 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KND87879.1 - 2.9e-14 52.7 0.0 9.9e-14 51.0 0.0 2.0 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Voltage_CLC PF00654.15 KND87880.1 - 3.5e-89 299.3 26.9 3.5e-89 299.3 18.7 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KND87880.1 - 8.3e-14 51.1 0.1 8.1e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain TFIIA_gamma_C PF02751.9 KND87882.1 - 7.9e-27 92.8 1.1 1.1e-26 92.4 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KND87882.1 - 4.9e-25 86.8 0.4 6.9e-25 86.3 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain EmrE PF13536.1 KND87883.1 - 0.0032 17.6 7.0 0.0032 17.6 4.9 1.6 1 1 1 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KND87883.1 - 0.005 16.8 12.0 0.01 15.9 8.3 1.5 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 KND87883.1 - 0.0069 16.1 2.4 0.0088 15.8 1.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 TPT PF03151.11 KND87883.1 - 0.23 11.0 10.0 5.9 6.5 6.8 2.0 1 1 1 2 2 2 0 Triose-phosphate Transporter family Pkinase PF00069.20 KND87884.1 - 2e-05 23.9 0.1 2.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND87884.1 - 0.0001 21.4 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GRAM PF02893.15 KND87885.1 - 1.4e-16 59.7 0.0 2.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain PepSY_TM_3 PF13706.1 KND87885.1 - 3.3 7.1 4.8 5.8 6.4 3.3 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix NOA36 PF06524.7 KND87885.1 - 8.1 5.5 10.1 0.38 9.9 1.2 2.2 2 0 0 2 2 2 0 NOA36 protein adh_short PF00106.20 KND87886.1 - 5.6e-60 202.0 13.5 4.1e-30 104.8 1.9 2.5 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KND87886.1 - 1.3e-30 105.3 0.0 3.1e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KND87886.1 - 1.6e-28 99.6 5.9 5.6e-14 52.2 0.3 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 KND87886.1 - 7.6e-06 25.7 0.0 0.00035 20.3 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KND87886.1 - 0.00051 19.1 0.4 0.0062 15.6 0.1 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KND87886.1 - 0.019 14.4 5.6 0.1 11.9 0.1 2.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KND87886.1 - 0.11 12.3 4.0 0.33 10.7 0.1 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_23 PF13489.1 KND87887.1 - 3.6e-15 56.0 0.0 5e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87887.1 - 1.9e-12 47.4 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87887.1 - 1.1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87887.1 - 2.4e-07 30.4 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87887.1 - 4.2e-06 27.3 0.0 7.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KND87887.1 - 0.00084 18.1 0.0 0.0011 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KND87887.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 KND87887.1 - 0.0088 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family RrnaAD PF00398.15 KND87887.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ACPS PF01648.15 KND87888.1 - 4.5e-11 42.5 0.0 1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DHC_N1 PF08385.7 KND87890.1 - 1.3e-191 637.9 0.2 1.3e-191 637.9 0.1 5.4 6 1 0 7 7 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KND87890.1 - 7.5e-129 429.8 3.3 7.5e-129 429.8 2.3 5.4 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KND87890.1 - 1.5e-105 353.8 0.0 4.1e-105 352.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KND87890.1 - 4.9e-78 261.8 0.0 1.1e-77 260.6 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KND87890.1 - 4e-42 143.6 0.1 1.2e-41 142.0 0.1 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KND87890.1 - 2e-39 135.1 0.1 2.2e-38 131.8 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KND87890.1 - 1.5e-38 132.4 10.8 3.4e-38 131.2 7.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KND87890.1 - 7.5e-32 109.9 0.0 6.9e-12 45.2 0.0 6.6 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KND87890.1 - 1.8e-20 73.1 0.0 3e-19 69.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KND87890.1 - 6.9e-14 52.1 3.5 0.022 14.9 0.0 6.7 7 1 0 7 7 6 3 AAA domain AAA PF00004.24 KND87890.1 - 4.2e-13 49.6 0.0 0.0028 17.8 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND87890.1 - 2.2e-10 41.4 0.1 0.04 14.7 0.0 6.2 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 KND87890.1 - 5.3e-10 39.3 0.1 0.33 10.8 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 KND87890.1 - 2.3e-08 34.4 4.9 0.048 13.9 0.0 6.7 7 0 0 7 7 6 2 AAA domain AAA_16 PF13191.1 KND87890.1 - 3.8e-07 30.2 20.9 0.19 11.6 0.1 9.1 8 2 1 9 9 8 2 AAA ATPase domain AAA_29 PF13555.1 KND87890.1 - 2.1e-06 27.1 0.0 0.32 10.5 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SE PF00437.15 KND87890.1 - 8.3e-06 24.8 0.0 0.089 11.6 0.0 3.6 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_14 PF13173.1 KND87890.1 - 8.9e-06 25.6 0.0 0.27 11.1 0.0 5.1 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 KND87890.1 - 2.8e-05 23.7 0.1 0.89 9.3 0.0 4.4 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 KND87890.1 - 0.00015 21.0 0.9 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KND87890.1 - 0.00025 21.3 1.5 6.2 7.1 0.0 4.9 4 0 0 4 4 4 0 ABC transporter BRE1 PF08647.6 KND87890.1 - 0.00034 20.5 3.5 0.00034 20.5 2.4 4.9 6 0 0 6 6 3 1 BRE1 E3 ubiquitin ligase AAA_25 PF13481.1 KND87890.1 - 0.006 16.0 0.1 0.49 9.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KND87890.1 - 0.012 15.8 0.1 36 4.5 0.0 4.6 4 0 0 4 4 4 0 RNA helicase Zeta_toxin PF06414.7 KND87890.1 - 0.016 14.2 6.4 0.95 8.5 0.0 4.2 5 0 0 5 5 4 0 Zeta toxin MobB PF03205.9 KND87890.1 - 0.024 14.3 0.3 11 5.7 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1774 PF08611.5 KND87891.1 - 4.4e-32 110.1 5.8 4.4e-32 110.1 4.0 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) zf-C2H2_4 PF13894.1 KND87892.1 - 0.0014 18.7 14.9 0.18 12.1 0.1 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger Collagen PF01391.13 KND87893.1 - 8.5e-05 22.0 11.9 8.5e-05 22.0 8.2 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Fungal_trans PF04082.13 KND87894.1 - 9.1e-19 67.3 0.0 1.4e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND87894.1 - 9.9e-10 38.1 9.6 1.7e-09 37.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4131 PF13567.1 KND87895.1 - 1.3 8.4 14.1 2.1 7.7 3.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) JAB PF01398.16 KND87896.1 - 1.6e-06 27.8 0.0 5.4e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KND87896.1 - 0.019 15.0 0.4 0.14 12.2 0.3 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Vps5 PF09325.5 KND87897.1 - 1.1e-14 54.3 1.2 1.5e-14 53.8 0.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KND87897.1 - 1.4e-09 37.7 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 PX domain TACC PF05010.9 KND87897.1 - 0.024 14.3 2.1 0.12 12.0 0.4 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) TPR_12 PF13424.1 KND87897.1 - 0.12 12.2 0.8 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Aconitase PF00330.15 KND87898.1 - 7.8e-172 571.9 0.0 9.3e-172 571.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KND87898.1 - 2.6e-45 153.7 0.0 4.8e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain EF-hand_7 PF13499.1 KND87899.1 - 2.4e-29 101.2 13.6 2.4e-13 49.9 0.9 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KND87899.1 - 4.6e-25 84.9 13.5 3e-08 32.3 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KND87899.1 - 5.5e-24 81.8 4.3 3.4e-06 26.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KND87899.1 - 1e-17 62.5 14.4 2.3e-05 23.5 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KND87899.1 - 2e-14 52.9 13.5 1.3e-05 24.7 0.9 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KND87899.1 - 2.4e-09 36.8 8.5 0.0033 17.1 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KND87899.1 - 4.9e-05 23.1 0.6 0.013 15.3 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KND87899.1 - 0.0009 19.2 2.5 0.35 10.9 0.2 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KND87899.1 - 0.0056 16.3 4.8 0.33 10.6 0.1 4.0 5 0 0 5 5 5 1 EF hand EF-hand_2 PF09068.6 KND87899.1 - 0.0091 16.0 0.1 1.4 8.9 0.0 3.1 3 1 0 3 3 3 1 EF hand DUF1679 PF07914.6 KND87899.1 - 0.011 14.4 0.7 1.7 7.1 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Toprim PF01751.17 KND87899.1 - 0.023 14.6 0.0 1.4 8.9 0.0 2.3 1 1 0 1 1 1 0 Toprim domain CDC45 PF02724.9 KND87900.1 - 5.5e-223 741.5 0.1 1.1e-221 737.2 0.1 3.1 1 1 0 1 1 1 1 CDC45-like protein DUF2360 PF10152.4 KND87900.1 - 1.3 9.2 5.9 0.34 11.1 0.6 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Methyltransf_23 PF13489.1 KND87901.1 - 6.7e-14 51.9 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND87901.1 - 3.4e-08 34.0 0.0 4.2e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND87901.1 - 1.5e-06 28.6 0.0 9.2e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87901.1 - 2.6e-06 27.0 0.0 4.8e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87901.1 - 7.2e-06 26.4 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KND87901.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KND87901.1 - 0.021 13.8 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 KND87901.1 - 0.035 14.0 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 KND87901.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain UPF0146 PF03686.8 KND87901.1 - 0.077 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_25 PF13649.1 KND87901.1 - 0.097 13.0 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF2418 PF10332.4 KND87902.1 - 4.3e-34 116.7 0.1 8e-34 115.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Gly_transf_sug PF04488.10 KND87904.1 - 1.3e-07 31.9 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KND87904.1 - 0.0024 16.4 0.2 0.0043 15.5 0.1 1.3 1 1 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF3425 PF11905.3 KND87905.1 - 2.8e-24 85.5 0.1 5.7e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) GTP_EFTU PF00009.22 KND87906.1 - 3.5e-60 202.6 0.2 5e-60 202.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KND87906.1 - 1.7e-36 124.3 0.0 5.9e-36 122.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 KND87906.1 - 4.2e-13 49.2 2.3 9.2e-13 48.1 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KND87906.1 - 3.8e-12 45.8 0.0 1.5e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KND87906.1 - 6.9e-12 45.0 0.0 6.8e-06 25.8 0.0 2.8 1 1 1 2 2 2 2 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KND87906.1 - 0.00027 20.8 0.1 0.0006 19.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAD_M PF08527.5 KND87906.1 - 0.036 13.4 0.0 0.099 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain PduV-EutP PF10662.4 KND87906.1 - 0.068 12.6 0.2 0.24 10.8 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MTHFR PF02219.12 KND87908.1 - 1.6e-112 375.2 0.0 2.6e-112 374.6 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RRM_6 PF14259.1 KND87909.1 - 1.5e-10 40.8 0.1 9.4e-10 38.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND87909.1 - 1.3e-09 37.7 0.1 2.5e-08 33.6 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND87909.1 - 2.2e-07 30.4 0.2 2.5e-05 23.7 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND87909.1 - 1.3e-06 28.0 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KND87909.1 - 6.5e-05 22.5 4.1 0.00011 21.7 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KND87909.1 - 0.0015 18.5 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 PWI domain DUF1330 PF07045.6 KND87909.1 - 0.029 14.2 0.1 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) V_ATPase_I PF01496.14 KND87909.1 - 0.041 11.7 1.7 0.058 11.2 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NUMOD4 PF07463.6 KND87910.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NUMOD4 motif zf-C2H2_6 PF13912.1 KND87911.1 - 0.00088 19.0 0.2 0.00088 19.0 0.1 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 KND87911.1 - 0.038 13.7 0.3 0.038 13.7 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 KND87911.1 - 1.4 8.8 12.1 0.068 13.0 4.3 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Solute_trans_a PF03619.11 KND87912.1 - 2.3e-105 351.8 5.6 2.7e-105 351.5 3.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.7 KND87913.1 - 2.6e-150 501.4 0.0 3.6e-150 500.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Zip PF02535.17 KND87914.1 - 4.8e-54 183.5 6.6 1.7e-53 181.6 4.6 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.13 KND87915.1 - 2.3e-05 23.5 0.0 4.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.7 KND87916.1 - 9.4e-40 136.9 23.5 6.5e-39 134.1 16.3 2.0 1 1 0 1 1 1 1 Hamartin protein Fucose_iso_C PF02952.12 KND87916.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain V_ATPase_I PF01496.14 KND87916.1 - 8.5 4.0 21.1 30 2.2 14.7 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4066 PF13278.1 KND87917.1 - 3.2e-22 78.5 0.1 2e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KND87917.1 - 5.1e-06 26.0 0.0 9.8e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 KND87917.1 - 0.047 12.5 0.0 0.17 10.7 0.0 1.7 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KND87917.1 - 0.054 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Pyridoxal_deC PF00282.14 KND87918.1 - 4.6e-112 374.1 0.0 5.5e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1382 PF07131.6 KND87918.1 - 0.013 15.5 0.1 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) DUF814 PF05670.8 KND87918.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF814) EMP70 PF02990.11 KND87919.1 - 4e-150 500.7 0.0 1.1e-140 469.6 0.0 2.5 1 1 1 2 2 2 2 Endomembrane protein 70 Bul1_N PF04425.7 KND87920.1 - 3.1e-06 26.0 0.0 0.0003 19.4 0.0 2.3 2 0 0 2 2 2 2 Bul1 N terminus Bul1_C PF04426.7 KND87920.1 - 3.3e-05 23.2 0.0 9.1e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_C PF02752.17 KND87920.1 - 0.11 12.6 0.1 1.1 9.4 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Phospholip_A2_3 PF09056.6 KND87921.1 - 1.5e-34 118.5 2.0 2e-34 118.1 1.4 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 ATP_bind_1 PF03029.12 KND87922.1 - 7.2e-77 258.1 0.0 1e-76 257.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KND87922.1 - 0.0034 16.2 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 KND87922.1 - 0.0088 15.1 0.3 0.05 12.6 0.0 2.2 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.1 KND87922.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KND87922.1 - 0.015 16.1 1.1 0.015 16.1 0.8 2.8 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KND87922.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KND87922.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain cNMP_binding PF00027.24 KND87923.1 - 2.2e-40 136.3 0.1 1.1e-18 66.7 0.0 4.6 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KND87923.1 - 9.2e-18 64.9 4.2 5.3e-17 62.4 2.9 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.11 KND87924.1 - 1.2e-38 132.7 35.5 1.2e-38 132.7 24.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND87924.1 - 7.8e-12 44.5 6.2 7.8e-12 44.5 4.3 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KND87924.1 - 0.0043 15.2 7.9 0.019 13.1 0.4 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector ATP-synt_DE_N PF02823.11 KND87926.1 - 5.2e-18 64.5 0.1 9.1e-18 63.8 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.4 KND87927.1 - 1.9e-121 406.0 47.1 1.9e-121 406.0 32.6 3.0 2 2 0 2 2 2 1 Protein of unknown function (DUF2457) TFIIA PF03153.8 KND87927.1 - 5.4e-05 23.2 16.8 5.4e-05 23.2 11.6 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 KND87927.1 - 0.87 8.9 18.4 1.8 7.9 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 KND87927.1 - 0.95 8.6 26.6 0.13 11.5 14.8 2.0 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 KND87927.1 - 2.5 5.8 31.9 0.1 10.5 18.0 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 KND87927.1 - 7.8 4.4 25.5 1.7 6.5 12.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Methyltransf_PK PF05891.7 KND87928.1 - 2.1e-65 220.0 0.1 3.5e-51 173.6 0.0 2.1 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Succ_CoA_lig PF13607.1 KND87928.1 - 0.0025 17.3 0.0 0.008 15.7 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain zf-C3HC4 PF00097.20 KND87929.1 - 8.7e-05 22.0 5.2 0.00024 20.7 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND87929.1 - 0.016 15.2 5.1 0.043 13.8 3.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 KND87929.1 - 0.05 13.4 5.0 0.15 11.9 3.5 1.7 1 0 0 1 1 1 0 IBR domain bZIP_1 PF00170.16 KND87930.1 - 0.0035 17.2 15.0 0.0052 16.7 10.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Phlebovirus_NSM PF07246.6 KND87930.1 - 0.0049 16.0 3.6 0.0074 15.4 2.5 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M bZIP_2 PF07716.10 KND87930.1 - 0.032 14.0 16.5 0.059 13.2 11.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF349 PF03993.7 KND87930.1 - 1.3 9.2 10.1 2 8.6 6.6 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DivIC PF04977.10 KND87930.1 - 3.2 7.2 10.2 0.48 9.9 3.9 1.8 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KND87930.1 - 3.5 6.5 9.6 5 6.0 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KND87930.1 - 4.1 6.9 5.0 6 6.4 3.5 1.1 1 0 0 1 1 1 0 IncA protein SGL PF08450.7 KND87931.1 - 5.3e-61 206.1 0.0 6.7e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KND87931.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Arylesterase DUF3112 PF11309.3 KND87932.1 - 0.043 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Aldedh PF00171.17 KND87933.1 - 3.4e-172 572.9 0.0 3.8e-172 572.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Endonuc_subdom PF09062.5 KND87933.1 - 0.17 12.6 0.0 0.36 11.5 0.0 1.5 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain Arf PF00025.16 KND87934.1 - 2.2e-66 222.4 0.0 2.5e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KND87934.1 - 1.7e-09 36.8 0.2 6.3e-06 25.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KND87934.1 - 2.9e-08 34.2 0.0 4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KND87934.1 - 8.4e-08 31.7 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KND87934.1 - 2.7e-07 29.9 0.0 3.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KND87934.1 - 2.9e-07 30.4 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KND87934.1 - 8.4e-06 25.0 0.0 9.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND87934.1 - 0.00099 18.5 0.1 0.045 13.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.3 KND87934.1 - 0.05 12.8 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 KND87934.1 - 0.088 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAM74 PF15026.1 KND87935.1 - 0.016 14.8 1.7 0.035 13.7 1.2 1.5 1 0 0 1 1 1 0 FAM74 protein AMP-binding PF00501.23 KND87936.1 - 2.7e-64 217.1 1.9 9.1e-25 86.8 0.0 4.8 4 1 0 4 4 4 4 AMP-binding enzyme RicinB_lectin_2 PF14200.1 KND87937.1 - 2.6e-08 34.1 1.2 1.1e-07 32.1 0.6 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.5 KND87937.1 - 3.9e-05 22.8 0.4 8.2e-05 21.8 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glyco_hydro_31 PF01055.21 KND87938.1 - 1.4e-82 277.9 3.0 1.7e-82 277.6 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.19 KND87939.1 - 1.1e-57 195.6 6.9 1.3e-54 185.5 5.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KND87939.1 - 2.3e-14 52.9 13.4 2.3e-14 52.9 9.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 KND87939.1 - 0.0029 16.4 2.9 0.0047 15.7 2.0 1.3 1 0 0 1 1 1 1 PUCC protein Gamma-thionin PF00304.15 KND87940.1 - 0.0059 16.5 5.0 0.009 16.0 3.4 1.3 1 0 0 1 1 1 1 Gamma-thionin family OMP_b-brl PF13505.1 KND87940.1 - 0.66 9.8 3.2 0.8 9.6 2.2 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Response_reg PF00072.19 KND87941.1 - 1.5e-21 76.4 0.0 1.4e-14 54.0 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.4 KND87942.1 - 6.6e-22 78.3 12.6 1e-12 48.3 4.3 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) DUF2052 PF09747.4 KND87943.1 - 6.6e-22 78.3 12.6 1e-12 48.3 4.3 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Y_phosphatase3 PF13350.1 KND87944.1 - 1.2e-39 136.1 0.0 1.9e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KND87944.1 - 5e-15 55.3 0.2 5e-15 55.3 0.1 2.6 4 0 0 4 4 4 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KND87944.1 - 9.9e-06 25.0 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KND87944.1 - 3.6e-05 23.1 0.0 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KND87944.1 - 0.0061 16.1 0.0 0.066 12.8 0.2 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Bot1p PF12298.3 KND87945.1 - 1.5e-52 178.0 2.8 1.5e-52 178.0 1.9 1.7 2 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HTH_28 PF13518.1 KND87945.1 - 0.013 15.4 0.5 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DNA_pol3_a_NII PF11490.3 KND87945.1 - 0.27 10.8 4.3 0.44 10.1 2.9 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II TRAP-gamma PF07074.7 KND87945.1 - 1.6 8.2 6.4 0.5 9.8 2.3 1.6 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) adh_short PF00106.20 KND87946.1 - 1.2e-23 83.9 2.2 2.4e-16 60.0 0.6 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KND87946.1 - 1.5e-18 67.4 0.1 6.1e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND87946.1 - 8.8e-11 41.7 0.9 3e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KND87946.1 - 0.00053 19.7 0.6 0.001 18.8 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 KND87946.1 - 0.0097 15.0 0.0 0.023 13.8 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 KND87946.1 - 0.022 14.2 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND87946.1 - 0.4 10.6 3.5 0.84 9.6 0.6 2.5 2 1 1 3 3 3 0 NADH(P)-binding Abhydrolase_6 PF12697.2 KND87947.1 - 3.9e-29 102.1 0.0 5.7e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND87947.1 - 6.1e-10 39.0 0.0 9.9e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KND87947.1 - 0.074 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.20 KND87948.1 - 4.2e-17 62.0 0.0 1.9e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) SRRM_C PF15230.1 KND87948.1 - 0.13 12.3 11.2 1.6 8.8 1.6 3.0 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Acetyltransf_1 PF00583.19 KND87949.1 - 1.2e-11 44.4 0.1 2.2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND87949.1 - 8.2e-10 38.7 0.2 1.2e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND87949.1 - 0.0041 16.9 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND87949.1 - 0.007 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND87949.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PI-PLC-X PF00388.14 KND87950.1 - 3.9e-60 201.4 0.0 5.7e-60 200.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KND87950.1 - 1e-37 128.7 0.0 1.9e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF2207 PF09972.4 KND87951.1 - 0.018 13.6 0.6 0.027 13.0 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MerE PF05052.7 KND87951.1 - 0.09 12.7 4.9 0.062 13.2 1.2 2.2 2 0 0 2 2 2 0 MerE protein DUF4293 PF14126.1 KND87951.1 - 0.28 11.0 2.4 0.38 10.6 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) VIT1 PF01988.14 KND87951.1 - 0.67 9.4 12.8 0.057 12.9 4.4 2.0 1 1 0 2 2 2 0 VIT family Fungal_trans_2 PF11951.3 KND87953.1 - 7e-08 31.4 0.0 8.9e-08 31.1 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KND87954.1 - 2.8e-25 89.4 0.0 3.3e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND87954.1 - 4.2e-24 85.3 1.0 5.2e-24 85.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND87954.1 - 4.9e-13 49.1 0.1 7.6e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND87954.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ETF PF01012.16 KND87954.1 - 0.13 12.0 1.6 0.34 10.6 0.9 1.8 1 1 1 2 2 2 0 Electron transfer flavoprotein domain Med10 PF09748.4 KND87955.1 - 2.5e-37 127.5 0.0 3.3e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex TPR_11 PF13414.1 KND87956.1 - 1.9e-52 174.7 10.8 1.1e-21 76.2 1.2 5.8 4 2 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 KND87956.1 - 4.7e-39 129.1 12.0 6.8e-06 25.6 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 KND87956.1 - 5.2e-39 130.3 11.6 8.2e-08 31.5 0.0 7.8 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 KND87956.1 - 8.5e-31 105.9 7.1 2.3e-10 40.8 0.6 6.2 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KND87956.1 - 2.5e-28 98.2 10.0 8.6e-09 35.6 0.0 6.0 3 2 2 5 5 5 5 Tetratricopeptide repeat DnaJ PF00226.26 KND87956.1 - 1.6e-26 91.7 2.9 1.6e-26 91.7 2.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 KND87956.1 - 9.4e-22 75.5 15.8 2.8e-05 24.3 0.3 8.8 5 3 5 10 10 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND87956.1 - 1.6e-20 72.8 6.9 8.6e-06 25.6 0.0 5.6 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 KND87956.1 - 3.9e-19 66.9 6.9 0.0041 16.7 0.2 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KND87956.1 - 5.3e-19 66.7 13.4 0.00021 21.2 0.0 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 KND87956.1 - 2.2e-16 59.7 0.9 8.7e-07 28.9 0.0 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KND87956.1 - 1.1e-15 57.2 1.8 5.7e-05 22.8 0.1 5.1 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KND87956.1 - 1.5e-12 46.2 0.4 0.38 10.6 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND87956.1 - 3.9e-10 39.4 12.4 0.51 10.9 0.2 8.0 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 KND87956.1 - 4.7e-09 35.7 5.2 0.0023 17.0 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.12 KND87956.1 - 1e-05 25.8 3.0 0.049 13.9 0.0 4.5 3 2 2 5 5 4 1 Bacterial transcriptional activator domain TPR_20 PF14561.1 KND87956.1 - 2.7e-05 24.2 3.5 3.4 7.8 0.0 5.7 3 2 3 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 KND87956.1 - 8.3e-05 22.6 1.2 2.4 8.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KND87956.1 - 0.00067 19.9 1.1 2.2 8.5 0.0 3.5 2 1 2 4 4 4 1 Alkyl sulfatase dimerisation ChAPs PF09295.5 KND87956.1 - 0.0011 17.8 0.0 0.79 8.4 0.0 2.7 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.9 KND87956.1 - 0.0013 18.0 0.1 0.76 8.9 0.0 2.9 3 0 0 3 3 3 1 Coatomer epsilon subunit NARP1 PF12569.3 KND87956.1 - 0.0018 17.1 5.8 0.049 12.4 0.0 3.8 3 1 2 5 5 4 1 NMDA receptor-regulated protein 1 DUF3808 PF10300.4 KND87956.1 - 0.0019 16.8 0.1 0.23 9.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) SNAP PF14938.1 KND87956.1 - 0.0027 16.9 2.9 0.53 9.3 0.0 2.7 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.1 KND87956.1 - 0.0075 16.1 3.5 21 5.0 0.0 4.4 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KND87956.1 - 0.01 15.7 1.0 5.6 6.9 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain YfiO PF13525.1 KND87956.1 - 0.066 12.6 1.9 0.14 11.5 0.1 2.4 2 1 1 3 3 3 0 Outer membrane lipoprotein DUF3366 PF11846.3 KND87956.1 - 0.62 9.9 4.4 4.8 7.0 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3366) TPR_10 PF13374.1 KND87956.1 - 0.74 9.8 13.1 24 5.0 0.1 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF966 PF06136.8 KND87956.1 - 8.8 5.6 18.5 15 4.8 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) EF-hand_6 PF13405.1 KND87957.1 - 5.9e-13 47.5 0.7 5.8e-06 25.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KND87957.1 - 7.6e-10 37.3 1.1 0.00092 18.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KND87957.1 - 2.7e-08 33.8 1.3 2.4e-06 27.5 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KND87957.1 - 6e-08 31.6 4.2 0.0012 18.0 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KND87957.1 - 1.1e-06 28.1 0.0 0.063 12.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Esterase PF00756.15 KND87958.1 - 3.2e-47 161.0 0.0 3.7e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KND87958.1 - 1.3e-06 28.2 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND87958.1 - 0.00052 19.9 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KND87958.1 - 0.0013 18.0 0.0 0.0025 17.0 0.0 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.2 KND87958.1 - 0.0098 14.8 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KND87958.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 KND87958.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ran_BP1 PF00638.13 KND87959.1 - 5.2e-23 81.3 0.1 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Arrestin_N PF00339.24 KND87959.1 - 1.3e-08 34.7 0.0 4.9e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain bZIP_1 PF00170.16 KND87961.1 - 4.7e-06 26.4 7.8 1e-05 25.4 5.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND87961.1 - 0.1 12.4 6.7 0.34 10.7 4.6 1.9 1 0 0 1 1 1 0 Basic region leucine zipper rRNA_processing PF08524.6 KND87961.1 - 0.13 12.0 5.1 0.23 11.2 3.5 1.3 1 0 0 1 1 1 0 rRNA processing GvpL_GvpF PF06386.6 KND87961.1 - 0.28 10.7 4.2 0.42 10.1 2.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V-SNARE_C PF12352.3 KND87962.1 - 0.027 14.5 0.2 0.085 12.9 0.1 1.8 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus RIX1 PF08167.7 KND87963.1 - 3.7e-40 137.3 0.0 6.2e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Glyco_hydro_16 PF00722.16 KND87964.1 - 2.3e-09 36.8 1.4 3.5e-09 36.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Xpo1 PF08389.7 KND87965.1 - 2e-33 115.3 1.0 1.1e-32 113.0 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KND87965.1 - 0.00037 20.3 0.1 1.5 9.1 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat TPR_2 PF07719.12 KND87966.1 - 1.9e-09 36.7 13.8 0.32 11.0 0.0 7.6 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KND87966.1 - 7.3e-09 35.4 22.5 0.1 13.2 0.0 9.2 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND87966.1 - 9.9e-08 31.2 2.3 1.2 8.8 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND87966.1 - 1e-06 28.2 8.6 0.75 9.4 0.2 5.8 5 1 0 6 6 6 2 TPR repeat TPR_12 PF13424.1 KND87966.1 - 5.5e-06 26.2 11.9 0.8 9.6 0.2 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND87966.1 - 8.4e-06 25.2 0.4 0.011 15.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND87966.1 - 0.00022 21.1 2.2 0.13 12.4 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND87966.1 - 0.00064 20.0 11.5 0.1 12.9 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KND87966.1 - 0.0065 16.1 8.6 2.3 8.2 0.3 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND87966.1 - 0.0069 17.0 23.6 0.39 11.4 0.2 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND87966.1 - 0.017 14.9 2.6 0.11 12.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND87966.1 - 2 9.0 0.0 2 9.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND87966.1 - 9 7.0 13.2 20 5.9 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 KND87967.1 - 5.9e-08 32.6 0.0 2.6e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND87967.1 - 8.1e-08 32.3 0.0 2.1e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND87967.1 - 7.9e-07 29.2 0.0 0.00082 19.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND87967.1 - 2.7e-06 27.2 0.0 8.6e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND87967.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KND87967.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_CG PF14542.1 KND87967.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 KND87967.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Whi5 PF08528.6 KND87969.1 - 7.3e-09 35.0 0.1 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Peptidase_M18 PF02127.10 KND87970.1 - 6.4e-168 558.7 0.0 9.9e-168 558.1 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KND87970.1 - 0.00033 19.5 0.0 0.0028 16.4 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase ketoacyl-synt PF00109.21 KND87973.1 - 3.3e-63 213.5 0.0 3.9e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KND87973.1 - 7.8e-07 28.3 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KND87973.1 - 0.16 11.6 0.4 0.75 9.4 0.3 1.9 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.21 KND87974.1 - 4.2e-11 42.4 0.0 7.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND87974.1 - 1.2e-06 28.2 0.5 2.5e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 KND87975.1 - 1.6e-84 283.7 0.0 2.5e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.5 KND87975.1 - 2e-54 183.9 0.1 1.8e-49 167.8 0.0 2.6 2 0 0 2 2 2 2 KR domain PS-DH PF14765.1 KND87975.1 - 1.2e-45 155.9 0.0 2.5e-45 154.9 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 KND87975.1 - 5e-45 153.6 0.0 7.5e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KND87975.1 - 1.1e-44 152.2 0.0 2.3e-39 134.9 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 KND87975.1 - 5.2e-33 114.0 0.0 1.9e-32 112.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 KND87975.1 - 5.1e-20 72.0 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 KND87975.1 - 1.1e-17 64.0 1.7 1.3e-08 35.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KND87975.1 - 5.7e-16 58.7 0.0 1.8e-15 57.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KND87975.1 - 8.4e-12 45.2 0.1 2.1e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 KND87975.1 - 2.4e-11 43.5 0.0 6.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KND87975.1 - 1e-10 41.4 0.0 4e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KND87975.1 - 3.6e-10 40.3 0.0 9.1e-09 35.8 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND87975.1 - 9.2e-09 35.6 0.0 2.7e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND87975.1 - 1.2e-06 28.1 0.0 3.9e-06 26.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 KND87975.1 - 0.00055 19.9 0.2 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_25 PF13649.1 KND87975.1 - 0.00091 19.5 0.0 0.0027 18.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND87975.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RmlD_sub_bind PF04321.12 KND87975.1 - 0.018 13.9 0.0 0.081 11.8 0.0 2.1 3 0 0 3 3 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 KND87975.1 - 0.025 14.8 0.1 0.086 13.1 0.0 2.0 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain Cu-oxidase_2 PF07731.9 KND87975.1 - 0.05 13.1 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Multicopper oxidase NodS PF05401.6 KND87975.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Saccharop_dh PF03435.13 KND87975.1 - 0.11 11.4 0.1 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_16 PF10294.4 KND87975.1 - 0.16 11.3 0.0 0.84 9.0 0.0 2.1 2 1 0 2 2 1 0 Putative methyltransferase 3Beta_HSD PF01073.14 KND87975.1 - 0.36 9.4 0.0 12 4.4 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RrnaAD PF00398.15 KND87975.1 - 0.38 9.7 0.0 1.1 8.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase NmrA PF05368.8 KND87975.1 - 0.42 9.8 0.1 1.1 8.4 0.1 1.7 1 0 0 1 1 1 0 NmrA-like family AATase PF07247.7 KND87975.1 - 9.3 4.6 0.8 16 3.9 0.0 1.7 2 0 0 2 2 2 0 Alcohol acetyltransferase Ketoacyl-synt_C PF02801.17 KND87976.1 - 4.7e-31 107.0 0.1 4.7e-31 107.0 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KND87976.1 - 3.8e-25 88.9 0.5 5.8e-25 88.2 0.4 1.2 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KND87976.1 - 6.3e-06 25.8 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.11 KND87978.1 - 9.5e-07 27.8 7.7 0.0023 16.6 2.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PDEase_II PF02112.10 KND87983.1 - 1.6e-52 178.5 0.0 1.3e-23 83.4 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.22 KND87983.1 - 9.2e-05 22.1 0.1 0.00028 20.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND87983.1 - 0.15 11.5 0.9 0.44 10.0 0.6 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Flavin_Reduct PF01613.13 KND87984.1 - 8e-16 58.2 0.0 1.2e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Lactamase_B_2 PF12706.2 KND87985.1 - 3.5e-31 108.2 0.0 9.7e-31 106.8 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KND87985.1 - 2.5e-18 65.3 0.1 7.5e-18 63.7 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KND87985.1 - 7.5e-07 28.9 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 KND87986.1 - 4.6e-58 196.3 0.0 7.3e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND87986.1 - 3.2e-18 65.7 0.0 1.9e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND87986.1 - 0.017 13.9 0.2 0.027 13.2 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mtc PF03820.12 KND87987.1 - 1.5e-92 309.5 0.0 8.6e-92 307.0 0.0 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier Acetyltransf_9 PF13527.1 KND87988.1 - 0.00098 18.9 0.0 0.011 15.5 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND87988.1 - 0.0046 16.9 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND87988.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND87988.1 - 0.097 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 KND87989.1 - 1.7e-66 222.7 0.4 1.9e-66 222.5 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KND87989.1 - 1.7e-12 46.7 1.1 4.2e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KND87989.1 - 4e-12 45.8 0.0 4.7e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KND87989.1 - 5.7e-09 35.4 0.0 6.6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KND87989.1 - 8.3e-09 35.4 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KND87989.1 - 9.3e-09 34.7 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KND87989.1 - 1.2e-08 35.4 0.0 1.6e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KND87989.1 - 9.6e-06 25.1 0.0 0.00084 18.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KND87989.1 - 0.004 17.9 0.2 0.0061 17.3 0.1 1.3 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KND87989.1 - 0.026 14.0 0.1 0.094 12.2 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KND87989.1 - 0.044 13.0 0.2 0.089 12.0 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KND87989.1 - 0.062 13.1 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family DUF4045 PF13254.1 KND87990.1 - 4.3e-82 276.6 51.2 2.9e-44 152.0 22.0 7.4 4 3 4 8 8 8 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KND87990.1 - 1.3e-05 24.7 0.0 0.55 9.9 0.0 3.6 3 0 0 3 3 3 2 Gelsolin repeat GEMIN8 PF15348.1 KND87990.1 - 1.1 9.3 14.2 3.4 7.6 9.8 1.8 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 NPR3 PF03666.8 KND87990.1 - 4.1 5.8 7.2 9.3 4.6 5.0 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Acyltransferase PF01553.16 KND87991.1 - 6.9e-34 116.1 0.0 1.1e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 KND87991.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2347 PF09804.4 KND87992.1 - 3.7e-106 354.5 0.0 4.7e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KND87992.1 - 1.6e-46 158.5 0.0 2.6e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KND87992.1 - 6.9e-05 22.5 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KND87992.1 - 0.035 12.5 0.0 0.16 10.4 0.0 2.0 2 0 0 2 2 2 0 Transport protein Avl9 zf-C2H2 PF00096.21 KND87993.1 - 6.3e-25 85.9 62.5 6.7e-05 22.9 2.5 10.5 10 1 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND87993.1 - 4.3e-24 83.0 52.7 0.0029 17.8 0.1 10.3 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND87993.1 - 5.2e-14 51.7 56.9 0.0031 17.7 0.3 11.0 11 1 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KND87993.1 - 0.00031 20.7 29.0 5 7.4 1.2 8.0 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KND87993.1 - 0.0046 17.1 0.6 0.0046 17.1 0.4 9.2 9 1 1 10 10 10 2 C2H2-type zinc-finger domain zf-met PF12874.2 KND87993.1 - 0.0099 16.0 22.9 1.3 9.2 0.0 7.4 8 0 0 8 8 7 2 Zinc-finger of C2H2 type DUF4187 PF13821.1 KND87993.1 - 0.019 14.5 0.6 0.019 14.5 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) TF_Zn_Ribbon PF08271.7 KND87993.1 - 0.074 12.3 6.7 0.48 9.7 0.2 3.6 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 KND87993.1 - 0.11 12.1 2.7 4.6 6.9 0.2 3.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KND87993.1 - 0.13 12.0 2.7 5.8 6.6 0.2 3.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KND87993.1 - 0.5 10.2 18.7 0.43 10.4 0.4 4.2 3 1 1 4 4 4 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.8 KND87993.1 - 0.58 9.7 13.2 0.43 10.1 1.3 3.6 3 0 0 3 3 3 0 InsA N-terminal domain zf-C2HC_2 PF13913.1 KND87993.1 - 1.7 8.4 11.8 16 5.2 0.0 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type CHORD PF04968.7 KND87993.1 - 2 8.7 28.1 2.2 8.6 0.3 6.1 4 2 3 7 7 7 0 CHORD RNA_pol_Rpb6 PF01192.17 KND87994.1 - 1.4e-24 85.5 0.4 1.4e-24 85.5 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 Ligase_CoA PF00549.14 KND87994.1 - 0.099 12.2 1.4 0.2 11.2 0.5 1.8 2 1 0 2 2 2 0 CoA-ligase Methyltransf_27 PF13708.1 KND87995.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Tmemb_170 PF10190.4 KND87996.1 - 8.1e-06 25.8 8.1 1.1e-05 25.4 5.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Herpes_UL73 PF03554.8 KND87996.1 - 6 6.7 8.0 14 5.5 0.3 2.3 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein NfeD PF01957.13 KND87996.1 - 6.2 6.9 9.4 3 7.9 2.8 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding ICMT PF04140.9 KND87997.1 - 1.2e-26 92.6 1.5 1.3e-26 92.6 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KND87997.1 - 1e-13 51.2 8.7 1.4e-13 50.8 0.9 2.5 2 1 0 2 2 2 2 Phospholipid methyltransferase DUF1295 PF06966.7 KND87997.1 - 0.00042 19.7 0.2 0.00061 19.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TcpE PF12648.2 KND87997.1 - 9.8 6.3 7.7 0.6 10.2 0.3 2.4 2 1 1 3 3 3 0 TcpE family MBOAT PF03062.14 KND87998.1 - 8.2e-19 67.8 15.3 8.2e-19 67.8 10.6 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KND87998.1 - 0.00029 20.8 3.6 0.0012 18.9 2.5 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 KND88000.1 - 4.7e-50 165.7 17.6 2.2e-09 36.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KND88000.1 - 0.00048 19.8 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KND88000.1 - 0.033 12.9 0.0 0.42 9.2 0.1 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Sporozoite_P67 PF05642.6 KND88000.1 - 0.63 7.8 2.6 0.89 7.3 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Endonuclease_NS PF01223.18 KND88001.1 - 1.4e-60 204.4 0.0 1.8e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.17 KND88002.1 - 3.5e-33 114.9 0.6 4.6e-22 78.4 0.1 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter MFS_1 PF07690.11 KND88005.1 - 6.1e-25 87.6 31.4 6.7e-13 48.0 4.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KND88005.1 - 1.1e-05 24.0 17.8 1.9e-05 23.2 3.0 3.6 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KND88005.1 - 0.0032 17.2 1.9 5.2 6.9 0.1 3.8 3 0 0 3 3 3 2 MFS_1 like family TraL PF07178.6 KND88005.1 - 0.032 14.2 0.7 5.9 6.9 0.0 3.1 2 0 0 2 2 2 0 TraL protein Sugar_tr PF00083.19 KND88005.1 - 0.91 8.0 20.6 0.26 9.8 0.1 3.6 4 0 0 4 4 4 0 Sugar (and other) transporter Actin PF00022.14 KND88006.1 - 1.9e-31 108.8 0.0 1.8e-20 72.7 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KND88006.1 - 0.018 13.6 0.0 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein PHD PF00628.24 KND88007.1 - 2.7e-08 33.3 5.8 4.4e-08 32.6 4.0 1.3 1 0 0 1 1 1 1 PHD-finger DUF4661 PF15576.1 KND88007.1 - 0.11 12.1 0.7 0.25 10.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PHD_2 PF13831.1 KND88007.1 - 0.46 9.8 2.9 0.86 8.9 2.0 1.4 1 0 0 1 1 1 0 PHD-finger Iso_dh PF00180.15 KND88008.1 - 2.2e-81 273.5 0.0 6.6e-62 209.4 0.0 2.4 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF4451 PF14616.1 KND88009.1 - 7.4e-34 116.1 0.4 1.3e-33 115.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) HABP4_PAI-RBP1 PF04774.10 KND88011.1 - 1.2e-06 28.9 5.8 1.2e-06 28.9 4.0 2.5 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.5 KND88011.1 - 0.0072 16.9 6.1 0.0072 16.9 4.3 3.9 5 0 0 5 5 5 1 Stm1 DUF3336 PF11815.3 KND88013.1 - 4.4e-52 175.4 6.2 7.2e-52 174.7 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Sec63 PF02889.11 KND88013.1 - 1e-40 139.9 0.0 3.4e-40 138.1 0.0 1.9 2 1 0 2 2 2 1 Sec63 Brl domain Patatin PF01734.17 KND88013.1 - 1e-19 71.2 1.6 2e-19 70.3 0.0 2.4 3 0 0 3 3 3 1 Patatin-like phospholipase DnaJ PF00226.26 KND88013.1 - 6.7e-16 57.7 1.1 1.5e-15 56.6 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-bind_2 PF08914.6 KND88014.1 - 0.041 13.6 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Rap1 Myb domain Pkinase PF00069.20 KND88015.1 - 5.3e-36 124.0 0.0 9.2e-36 123.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88015.1 - 1.2e-20 73.7 0.0 1.7e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KND88015.1 - 1.3e-08 34.7 0.1 3.1e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-MYND PF01753.13 KND88016.1 - 1.1 9.2 26.8 0.2 11.5 3.0 3.9 4 0 0 4 4 4 0 MYND finger SF3b10 PF07189.6 KND88017.1 - 2.7e-34 116.8 0.0 3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 KND88018.1 - 2.3e-39 134.7 0.0 3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 MAGE family SLS PF14611.1 KND88019.1 - 2.7e-42 144.5 2.3 4.6e-42 143.8 1.6 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MFS_1 PF07690.11 KND88022.1 - 5.6e-16 58.1 58.3 1.2e-09 37.3 26.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.3 KND88022.1 - 0.018 14.5 0.4 0.018 14.5 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Tubulin PF00091.20 KND88023.1 - 1.4e-71 240.8 0.0 2.4e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KND88023.1 - 1.8e-43 147.6 0.0 2.7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KND88023.1 - 1.9e-06 27.8 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KND88023.1 - 0.0023 17.4 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF676 PF05057.9 KND88024.1 - 8e-07 28.5 0.0 1.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KND88024.1 - 1.4e-06 28.3 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND88024.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF829 PF05705.9 KND88024.1 - 0.00031 20.5 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) LCAT PF02450.10 KND88024.1 - 0.0018 17.3 0.0 0.0039 16.2 0.0 1.5 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 KND88024.1 - 0.0037 17.0 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 KND88024.1 - 0.0081 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Ser_hydrolase PF06821.8 KND88024.1 - 0.1 12.1 0.8 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Pyr_redox_3 PF13738.1 KND88025.1 - 4e-22 79.2 0.0 3.3e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND88025.1 - 1.2e-12 48.1 0.0 4.6e-10 39.7 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND88025.1 - 5.4e-10 38.7 0.0 2e-06 26.9 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KND88025.1 - 6e-10 37.9 0.0 3.1e-09 35.5 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND88025.1 - 9.8e-08 31.9 0.0 7.4e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND88025.1 - 3.1e-07 29.6 0.6 0.0018 17.2 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KND88025.1 - 6e-07 28.8 0.1 0.00012 21.2 0.2 2.9 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KND88025.1 - 1.1e-05 24.1 0.1 0.00052 18.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KND88025.1 - 2.4e-05 23.3 0.6 0.00026 19.9 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KND88025.1 - 6e-05 22.2 0.0 0.00053 19.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KND88025.1 - 7.1e-05 23.1 0.1 0.18 12.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND88025.1 - 0.00012 21.8 0.1 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KND88025.1 - 0.00025 20.7 0.2 0.75 9.4 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KND88025.1 - 0.00086 18.3 0.3 0.0032 16.4 0.1 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein TrkA_N PF02254.13 KND88025.1 - 0.00092 19.2 0.1 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 KND88025.1 - 0.00094 19.2 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KND88025.1 - 0.0011 18.1 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 KND88025.1 - 0.0027 16.8 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase ThiF PF00899.16 KND88025.1 - 0.0032 17.3 0.4 0.034 13.9 0.1 2.3 2 0 0 2 2 2 1 ThiF family GIDA PF01134.17 KND88025.1 - 0.012 14.4 0.5 0.99 8.1 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.7 KND88025.1 - 0.015 14.6 0.2 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KND88025.1 - 0.019 15.1 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 KND88025.1 - 0.082 12.3 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KND88025.1 - 0.15 11.4 0.3 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FA_desaturase PF00487.19 KND88027.1 - 5.1e-21 75.2 15.3 2.9e-12 46.6 3.0 2.2 2 0 0 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.3 KND88027.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fungal_trans_2 PF11951.3 KND88028.1 - 6.5e-12 44.7 0.1 2.2e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 KND88029.1 - 5.1e-17 62.6 0.0 1.2e-16 61.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND88029.1 - 4.3e-11 42.3 0.0 5.1e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KND88029.1 - 1.4e-09 36.7 0.0 9.8e-09 33.9 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KND88029.1 - 3.3e-07 30.4 0.0 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND88029.1 - 4.4e-06 26.6 0.0 3.6e-05 23.7 0.0 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND88029.1 - 0.00069 18.7 0.0 0.0017 17.5 0.0 1.7 1 1 0 1 1 1 1 Thi4 family DAO PF01266.19 KND88029.1 - 0.0012 17.8 0.0 0.41 9.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND88029.1 - 0.037 13.7 0.1 0.54 10.0 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding DUF3870 PF12986.2 KND88029.1 - 0.044 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) ECH PF00378.15 KND88030.1 - 1.1e-06 27.9 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MHYT PF03707.11 KND88032.1 - 2.6e-05 24.2 13.4 0.0029 17.6 0.3 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF4131 PF13567.1 KND88032.1 - 8.2 5.8 12.5 5.9 6.2 1.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Formyl_trans_N PF00551.14 KND88033.1 - 0.00046 19.7 0.0 0.0097 15.4 0.0 2.6 1 1 0 1 1 1 1 Formyl transferase Pribosyltran PF00156.22 KND88035.1 - 4.9e-20 71.5 0.1 1.8e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 KND88035.1 - 6.6e-13 48.3 3.7 1.8e-12 46.8 2.5 1.7 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.9 KND88035.1 - 3.8e-08 33.0 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase UPRTase PF14681.1 KND88035.1 - 0.00012 21.3 0.1 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.7 KND88035.1 - 0.0023 17.7 0.0 0.0072 16.2 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like PRTase_2 PF15609.1 KND88035.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase p450 PF00067.17 KND88036.1 - 1.3e-57 195.3 0.0 1.7e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PTS_EIIA_1 PF00358.15 KND88038.1 - 0.093 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF982 PF06169.7 KND88039.1 - 0.036 13.8 0.1 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF982) Flavodoxin_NdrI PF07972.6 KND88040.1 - 0.038 13.9 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like MFS_1 PF07690.11 KND88041.1 - 1.1e-33 116.4 31.1 1.1e-33 116.4 21.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_4 PF13147.1 KND88042.1 - 1.5e-11 44.8 13.4 2.8e-11 43.9 2.2 3.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 KND88042.1 - 8.5e-11 41.5 2.3 9.6e-08 31.7 0.3 4.0 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 KND88042.1 - 2.8e-09 37.0 0.3 3.4e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 KND88042.1 - 1.3e-06 27.8 7.6 4.2e-05 22.9 0.4 3.0 3 0 0 3 3 3 2 Amidohydrolase family p450 PF00067.17 KND88043.1 - 4.6e-45 154.0 0.0 6.3e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KND88044.1 - 1.5e-70 237.3 0.0 7.1e-57 192.5 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KND88044.1 - 1.1e-20 73.7 0.0 2e-16 59.8 0.0 3.5 4 1 0 4 4 4 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND88044.1 - 0.17 10.6 0.2 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.19 KND88045.1 - 5.5e-75 252.6 24.2 6.4e-75 252.4 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND88045.1 - 4.4e-19 68.4 54.7 3.8e-16 58.7 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 KND88045.1 - 0.0013 17.6 6.7 0.0026 16.6 4.6 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein Aldedh PF00171.17 KND88046.1 - 4.1e-146 486.9 0.0 4.7e-146 486.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_14 PF13428.1 KND88046.1 - 0.021 15.4 1.5 0.45 11.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KND88047.1 - 1.4e-20 73.2 0.0 2.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.8 KND88048.1 - 9.9e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KND88048.1 - 0.043 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) adh_short_C2 PF13561.1 KND88049.1 - 9.8e-29 100.8 0.1 3.5e-28 99.0 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND88049.1 - 1e-24 87.3 0.2 1.3e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND88049.1 - 2.6e-07 30.4 0.0 6.1e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND88049.1 - 0.005 16.2 0.1 0.0081 15.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 KND88049.1 - 0.019 15.3 0.1 0.1 12.9 0.0 2.0 1 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.13 KND88049.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_16 PF10294.4 KND88049.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 KND88051.1 - 1.3e-39 135.9 34.5 2.8e-36 124.9 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND88051.1 - 6.4e-09 34.9 3.5 6.4e-09 34.9 2.4 2.3 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KND88051.1 - 0.00059 18.1 0.4 0.00088 17.5 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 KND88051.1 - 0.51 9.6 2.3 3.7 6.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) GTP_EFTU PF00009.22 KND88052.1 - 4.2e-44 150.2 0.0 7.2e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KND88052.1 - 1.1e-35 121.7 1.7 1.8e-35 121.0 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KND88052.1 - 2.1e-17 63.0 1.0 5.6e-17 61.6 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KND88052.1 - 0.00049 19.6 0.2 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MFS_1 PF07690.11 KND88053.1 - 1.1e-35 123.0 51.0 1e-31 109.9 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND88053.1 - 8.5e-07 27.9 15.6 8.5e-07 27.9 10.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF2198 PF09964.4 KND88053.1 - 0.51 10.1 5.1 2.4 7.9 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) Med12 PF09497.5 KND88054.1 - 2e-27 94.9 0.2 5.1e-27 93.6 0.2 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KND88054.1 - 4.9e-06 25.3 0.2 0.029 12.8 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain Serpin PF00079.15 KND88054.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) Pyrid_oxidase_2 PF13883.1 KND88055.1 - 1.2e-39 135.7 0.0 2.1e-39 135.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fic PF02661.13 KND88059.1 - 5.3e-08 33.4 0.1 1.5e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family IBR PF01485.16 KND88061.1 - 3e-10 39.8 38.1 3.4e-06 26.8 5.7 3.8 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KND88061.1 - 5e-06 26.2 5.8 5e-06 26.2 4.0 3.5 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KND88061.1 - 0.00019 21.0 6.0 0.00019 21.0 4.2 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND88061.1 - 0.00027 20.5 6.6 0.00027 20.5 4.6 3.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND88061.1 - 0.0013 18.7 5.8 0.0013 18.7 4.0 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FAM91_C PF14648.1 KND88061.1 - 6.7 5.4 8.1 1.6 7.4 3.2 1.6 2 0 0 2 2 2 0 FAM91 C-terminus RhoGAP PF00620.22 KND88063.1 - 2e-42 144.3 0.0 4.6e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KND88063.1 - 7.9e-13 48.4 1.9 8.2e-13 48.3 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_MLP1_2 PF07926.7 KND88063.1 - 0.65 9.7 11.2 0.96 9.1 3.5 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KND88063.1 - 0.95 9.0 6.1 1.7 8.1 4.2 1.5 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 KND88063.1 - 1.2 8.0 11.8 0.14 11.1 4.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FUSC PF04632.7 KND88063.1 - 9.3 4.5 5.1 13 4.0 3.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Adaptin_N PF01602.15 KND88065.1 - 9.3e-111 370.7 0.3 1.4e-110 370.1 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KND88065.1 - 1.2e-58 197.1 3.1 2.5e-58 196.1 2.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KND88065.1 - 4.8e-14 52.3 1.7 0.00016 21.8 0.1 5.7 2 1 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.11 KND88065.1 - 0.011 16.1 0.0 10 6.9 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Alpha_adaptin_C PF02296.11 KND88065.1 - 0.026 14.4 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT PF02985.17 KND88065.1 - 0.031 14.3 6.8 0.85 9.8 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KND88065.1 - 0.51 10.8 3.8 0.76 10.3 0.7 2.8 2 0 0 2 2 2 0 HEAT-like repeat ATP12 PF07542.6 KND88066.1 - 1.5e-29 102.3 0.0 2.6e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein RRM_1 PF00076.17 KND88068.1 - 2.4e-15 55.9 0.0 9.2e-13 47.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88068.1 - 1.6e-09 37.5 0.0 4.5e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 KND88069.1 - 1.4e-23 83.5 2.2 3.9e-23 82.1 1.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND88069.1 - 5.6e-11 42.4 1.5 1.7e-09 37.6 1.1 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND88069.1 - 2.7e-06 27.3 0.0 6.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ras PF00071.17 KND88070.1 - 1e-50 171.3 0.0 1.2e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND88070.1 - 2.9e-19 69.6 0.0 5.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND88070.1 - 3.3e-09 36.2 0.0 4.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND88070.1 - 6.5e-06 25.7 0.1 6e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND88070.1 - 0.0004 20.3 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KND88070.1 - 0.0068 16.5 0.1 0.18 11.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND88070.1 - 0.022 14.7 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Scytalone_dh PF02982.9 KND88070.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase NB-ARC PF00931.17 KND88070.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain POP1 PF06978.6 KND88072.1 - 8e-54 182.1 10.8 8e-54 182.1 7.5 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KND88072.1 - 1.8e-27 94.9 0.1 5.8e-27 93.3 0.1 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain EAF PF09816.4 KND88073.1 - 1.5e-11 44.2 0.0 4.8e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Ric8 PF10165.4 KND88074.1 - 1.5e-58 198.6 0.1 1.7e-47 162.3 0.0 2.8 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn CDC14 PF08045.6 KND88074.1 - 0.031 13.4 0.1 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Mg_trans_NIPA PF05653.9 KND88075.1 - 1.6e-92 309.7 19.4 2.1e-92 309.3 13.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KND88075.1 - 1e-06 28.9 5.2 1e-06 28.9 3.6 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KND88075.1 - 2.3e-06 27.6 27.6 1.9e-05 24.7 4.7 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 KND88075.1 - 2 7.2 14.7 0.0086 14.9 3.2 1.9 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) adh_short PF00106.20 KND88076.1 - 9.9e-15 54.8 1.8 1.1e-14 54.6 0.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND88076.1 - 2e-06 27.5 0.4 3.4e-06 26.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 KND88077.1 - 7.1e-39 133.5 0.0 1.3e-38 132.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88077.1 - 9.8e-12 44.4 0.0 2.3e-05 23.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND88077.1 - 0.1 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase KorB_C PF06613.6 KND88078.1 - 0.13 11.7 0.3 0.23 10.9 0.1 1.5 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Pkinase PF00069.20 KND88080.1 - 1.2e-20 73.7 0.0 2.7e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88080.1 - 1.9e-07 30.4 0.1 5.4e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.17 KND88081.1 - 5.8e-42 143.7 11.3 7.3e-42 143.4 7.9 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND88081.1 - 4.7e-05 23.8 0.7 0.00032 21.2 0.1 2.6 2 1 0 2 2 2 1 Peptidase inhibitor I9 Sugar_tr PF00083.19 KND88082.1 - 4.4e-80 269.4 28.7 5e-80 269.2 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND88082.1 - 5.7e-19 68.0 53.3 2.3e-17 62.7 20.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.20 KND88083.1 - 1.2e-24 86.8 0.0 9.2e-24 83.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88083.1 - 7.9e-07 28.3 0.0 4.3e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4215 PF13948.1 KND88084.1 - 0.0073 16.5 9.4 0.0073 16.5 6.5 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4215) Prominin PF05478.6 KND88085.1 - 1.7 6.1 0.1 2.5 5.5 0.1 1.1 1 0 0 1 1 1 0 Prominin BNR_2 PF13088.1 KND88089.1 - 6.2e-22 78.1 0.7 1.1e-11 44.5 0.4 2.8 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KND88089.1 - 1.4e-06 27.2 30.0 0.22 11.5 0.2 7.1 6 0 0 6 6 6 4 BNR/Asp-box repeat DUF4185 PF13810.1 KND88089.1 - 0.002 17.1 4.8 3.1 6.6 0.0 3.9 2 2 1 4 4 4 2 Domain of unknown function (DUF4185) Mo-co_dimer PF03404.11 KND88089.1 - 0.005 16.4 2.5 0.56 9.8 0.0 3.4 5 0 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain BNR_3 PF13859.1 KND88089.1 - 0.0075 15.3 0.6 2.1 7.3 0.0 3.0 1 1 1 2 2 2 1 BNR repeat-like domain PSII_BNR PF14870.1 KND88089.1 - 0.016 14.2 3.5 4.8 6.0 0.2 4.1 4 1 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 Glyco_hydro_71 PF03659.9 KND88090.1 - 8.2e-72 241.8 3.2 1.1e-71 241.3 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 BetaGal_dom4_5 PF13364.1 KND88090.1 - 0.007 16.6 0.2 0.019 15.2 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Kdo PF06293.9 KND88093.1 - 3.9e-05 22.7 0.0 6.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND88093.1 - 5.2e-05 22.5 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF329 PF03884.9 KND88093.1 - 0.043 13.3 0.2 0.089 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) APH PF01636.18 KND88093.1 - 0.09 12.4 0.1 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M20 PF01546.23 KND88095.1 - 2.6e-26 92.2 0.1 3.7e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND88095.1 - 2.5e-09 36.8 0.1 7.2e-09 35.3 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain ABC_tran PF00005.22 KND88096.1 - 8.3e-44 149.2 0.0 2.7e-25 89.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND88096.1 - 6.9e-27 94.5 17.4 1.5e-14 54.1 3.0 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KND88096.1 - 8.5e-13 48.0 0.5 0.0027 16.9 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND88096.1 - 5.5e-10 39.6 0.0 0.048 13.6 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 KND88096.1 - 2.3e-09 36.9 0.2 0.0026 17.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 KND88096.1 - 1.6e-07 30.5 0.0 0.0008 18.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KND88096.1 - 1.6e-07 30.7 0.3 0.025 14.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KND88096.1 - 5.7e-07 29.2 1.0 0.052 12.9 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 KND88096.1 - 7e-07 29.7 0.0 0.00021 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KND88096.1 - 7.2e-07 29.4 0.2 0.032 14.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KND88096.1 - 2.7e-05 23.7 0.0 0.027 13.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KND88096.1 - 4.3e-05 23.5 2.8 0.16 11.9 0.3 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 KND88096.1 - 9.3e-05 23.2 2.3 0.17 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KND88096.1 - 0.00013 21.7 2.6 0.11 12.1 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KND88096.1 - 0.00015 21.4 2.5 0.025 14.3 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KND88096.1 - 0.00015 22.0 0.3 0.68 10.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KND88096.1 - 0.00023 20.8 0.5 0.55 9.8 0.1 2.7 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 KND88096.1 - 0.00026 20.2 0.1 0.23 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF2075 PF09848.4 KND88096.1 - 0.00054 19.0 0.4 0.34 9.8 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KND88096.1 - 0.0007 19.8 0.7 1.9 8.6 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KND88096.1 - 0.00078 19.3 0.2 0.13 12.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DEAD PF00270.24 KND88096.1 - 0.0012 18.3 0.7 5.9 6.3 0.2 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase Dynamin_N PF00350.18 KND88096.1 - 0.0014 18.4 1.4 1.2 8.8 0.2 2.3 2 0 0 2 2 2 2 Dynamin family Viral_helicase1 PF01443.13 KND88096.1 - 0.0014 18.1 0.1 0.27 10.7 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KND88096.1 - 0.0016 17.9 3.8 0.043 13.2 0.8 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 KND88096.1 - 0.0016 18.2 4.1 0.012 15.4 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KND88096.1 - 0.0018 18.7 0.1 2.9 8.4 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 KND88096.1 - 0.002 18.0 0.3 1.1 9.2 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.7 KND88096.1 - 0.002 17.4 0.3 1.3 8.2 0.1 2.2 2 0 0 2 2 2 1 Poxvirus A32 protein IstB_IS21 PF01695.12 KND88096.1 - 0.0022 17.4 0.0 2.8 7.3 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.1 KND88096.1 - 0.0023 17.8 9.6 0.11 12.3 0.9 3.9 4 1 0 4 4 2 2 AAA domain TrwB_AAD_bind PF10412.4 KND88096.1 - 0.0054 15.4 0.8 2.2 6.7 0.1 2.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 KND88096.1 - 0.0084 15.2 0.6 2.3 7.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KND88096.1 - 0.014 15.2 0.1 0.58 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KND88096.1 - 0.014 15.0 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 KND88096.1 - 0.018 13.9 0.7 0.78 8.5 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 KND88096.1 - 0.021 14.5 2.9 3 7.5 0.4 2.6 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 KND88096.1 - 0.026 13.7 0.2 3.4 6.8 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 KND88096.1 - 0.035 14.2 0.2 16 5.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase CbiA PF01656.18 KND88096.1 - 0.038 13.3 0.8 3.1 7.1 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 KND88096.1 - 0.039 13.5 1.7 2.2 7.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KND88096.1 - 0.043 13.3 6.8 3.2 7.2 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KND88096.1 - 0.054 13.4 2.0 2.5 8.0 0.2 3.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KND88096.1 - 0.079 12.6 1.6 3.1 7.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 KND88096.1 - 0.08 11.5 0.0 1 7.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein ResIII PF04851.10 KND88096.1 - 0.086 12.6 0.0 11 5.7 0.0 2.5 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KND88096.1 - 0.13 11.3 0.2 14 4.7 0.0 2.5 2 0 0 2 2 2 0 KaiC Zot PF05707.7 KND88096.1 - 0.13 11.7 0.1 18 4.7 0.0 2.6 3 0 0 3 3 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KND88096.1 - 0.21 11.1 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KND88096.1 - 0.21 10.9 0.2 8.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 KND88096.1 - 0.28 9.7 1.2 6.3 5.2 0.1 2.6 3 0 0 3 3 2 0 Predicted ATPase of the ABC class AIG1 PF04548.11 KND88096.1 - 0.34 9.9 0.5 2.3 7.2 0.1 2.2 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.12 KND88096.1 - 0.35 10.3 2.6 9.3 5.7 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_32 PF13654.1 KND88096.1 - 0.38 9.3 0.0 7.7 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KND88096.1 - 0.45 9.3 2.4 5.4 5.8 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.13 KND88096.1 - 0.61 9.0 0.1 31 3.4 0.0 2.2 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KND88096.1 - 0.79 9.2 2.0 30 4.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Acatn PF13000.2 KND88097.1 - 1.3e-153 512.5 21.8 3.5e-79 266.7 6.2 3.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DFP PF04127.10 KND88098.1 - 1e-12 48.0 0.0 2.8e-05 23.8 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein CENP-O PF09496.5 KND88100.1 - 3.2e-21 75.3 0.0 5.3e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Pkinase PF00069.20 KND88101.1 - 4.2e-58 196.5 0.0 2.7e-57 193.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88101.1 - 2.1e-28 99.1 0.3 5.2e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KND88101.1 - 6.1e-06 26.6 2.0 8.8e-06 26.1 0.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KND88101.1 - 0.0006 18.8 0.4 0.0034 16.3 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KND88101.1 - 0.0047 16.6 0.2 0.092 12.4 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KND88101.1 - 0.24 10.2 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Na_H_Exchanger PF00999.16 KND88102.1 - 4.2e-29 101.2 35.1 7.7e-27 93.8 19.8 2.9 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Wbp11 PF09429.5 KND88102.1 - 1.9e-22 79.0 9.5 3.7e-22 78.0 6.6 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 Iso_dh PF00180.15 KND88103.1 - 6.8e-107 357.4 0.0 7.9e-107 357.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Yae1_N PF09811.4 KND88104.1 - 3.6e-13 48.7 0.7 5.4e-13 48.2 0.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal APG12 PF04110.8 KND88105.1 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NUT_N PF12881.2 KND88105.1 - 0.32 10.0 5.3 0.49 9.4 3.7 1.2 1 0 0 1 1 1 0 NUT protein N terminus Lyase_aromatic PF00221.14 KND88106.1 - 1.6e-136 455.5 4.0 5.5e-85 285.6 0.7 2.1 1 1 1 2 2 2 2 Aromatic amino acid lyase DUF572 PF04502.8 KND88107.1 - 8.2e-46 156.7 0.0 1.1e-45 156.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pantoate_transf PF02548.10 KND88109.1 - 1.3e-99 332.5 0.1 1.5e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KND88109.1 - 4.1e-10 39.2 0.3 7e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NmrA PF05368.8 KND88110.1 - 1.6e-26 92.9 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND88110.1 - 2.1e-16 60.4 0.2 2.8e-16 60.0 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND88110.1 - 0.00012 21.6 0.1 0.00023 20.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KND88110.1 - 0.00016 20.8 0.3 0.00022 20.3 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KND88110.1 - 0.00033 20.6 0.8 0.0006 19.7 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KND88110.1 - 0.00043 20.1 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KND88110.1 - 0.00044 19.0 0.0 0.00076 18.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND88110.1 - 0.0072 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KND88110.1 - 0.0085 16.3 0.1 0.024 14.9 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KND88110.1 - 0.053 13.1 0.3 0.12 12.0 0.2 1.7 1 1 0 1 1 1 0 KR domain Fungal_trans PF04082.13 KND88111.1 - 4.1e-11 42.2 4.1 6.5e-11 41.5 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88111.1 - 3.8e-07 29.9 8.4 8.9e-07 28.7 5.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KND88111.1 - 3.7e-06 26.9 16.8 0.00081 19.5 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND88111.1 - 0.00018 21.6 19.1 0.003 17.7 2.4 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger Neurochondrin PF05536.6 KND88111.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Neurochondrin zf-H2C2_2 PF13465.1 KND88111.1 - 0.16 12.3 0.3 0.16 12.3 0.2 3.6 3 1 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.11 KND88112.1 - 1.1e-30 106.5 25.4 1.2e-15 57.1 7.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KND88112.1 - 0.00033 20.3 2.2 0.0045 16.7 0.4 2.6 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.1 KND88112.1 - 0.0029 16.0 29.1 0.55 8.5 2.3 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 KND88112.1 - 0.022 13.3 23.7 0.034 12.7 7.0 3.4 2 2 1 3 3 3 0 Sugar (and other) transporter MFS_3 PF05977.8 KND88112.1 - 0.16 10.0 18.7 0.068 11.2 4.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Synaptobrevin PF00957.16 KND88113.1 - 0.055 13.0 0.2 0.13 11.8 0.1 1.7 1 1 1 2 2 2 0 Synaptobrevin SNARE PF05739.14 KND88113.1 - 0.063 12.9 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 SNARE domain ArfGap PF01412.13 KND88114.1 - 3.9e-41 139.5 1.1 5.8e-41 138.9 0.7 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Thiolase_N PF00108.18 KND88116.1 - 2.7e-77 259.3 4.7 3.8e-77 258.8 3.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND88116.1 - 9e-41 138.1 0.3 3.6e-40 136.1 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KND88116.1 - 0.03 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal OCD_Mu_crystall PF02423.10 KND88117.1 - 1.2e-16 60.3 0.2 2.1e-14 53.0 0.1 2.4 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Cg6151-P PF10233.4 KND88118.1 - 3.5e-34 117.1 13.5 4.2e-34 116.9 9.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TRP PF06011.7 KND88118.1 - 0.13 10.7 8.7 0.16 10.5 6.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF2518 PF10726.4 KND88118.1 - 0.29 10.6 6.4 0.53 9.8 0.3 2.1 2 0 0 2 2 2 0 Protein of function (DUF2518) Cytochrom_B558a PF05038.8 KND88118.1 - 3.5 7.1 7.5 8.5 5.9 5.2 1.7 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF1430 PF07242.6 KND88118.1 - 3.6 7.6 10.4 1.1 9.3 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF3210 PF11489.3 KND88119.1 - 1.3e-180 602.5 81.9 1.3e-180 602.5 56.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3210) Glyco_hydro_16 PF00722.16 KND88120.1 - 8e-43 145.8 2.6 8e-43 145.8 1.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_M4_C PF02868.10 KND88121.1 - 5.9e-47 159.4 0.0 9.5e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 KND88121.1 - 5.5e-21 75.2 0.1 8.6e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 KND88121.1 - 0.039 13.1 0.2 0.11 11.6 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M13 Glyco_hydro_18 PF00704.23 KND88122.1 - 3.6e-50 171.3 0.0 7.9e-50 170.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KND88122.1 - 6e-12 45.2 0.0 9.2e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 KND88122.1 - 0.008 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Prenyltrans PF00432.16 KND88124.1 - 4.7e-26 90.0 28.2 5.3e-07 29.1 0.3 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KND88124.1 - 8.3e-17 61.6 0.0 3.8e-10 40.1 0.0 4.1 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KND88124.1 - 0.00031 20.7 0.1 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 Prenyltransferase-like Zn_clus PF00172.13 KND88125.1 - 0.0031 17.3 7.7 0.0066 16.3 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92 PF07971.7 KND88126.1 - 3e-116 389.0 0.0 3.4e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 SIR2 PF02146.12 KND88127.1 - 2.2e-29 102.4 0.0 6.3e-29 100.9 0.0 1.7 1 1 0 1 1 1 1 Sir2 family BRAP2 PF07576.7 KND88128.1 - 3.3e-22 78.1 0.0 5.8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KND88128.1 - 9.2e-19 67.3 7.7 2.2e-18 66.0 5.4 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KND88128.1 - 1.7e-10 40.5 9.7 1.7e-10 40.5 6.7 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 KND88128.1 - 8.4e-06 25.4 7.5 8.4e-06 25.4 5.2 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND88128.1 - 1.8e-05 24.3 8.3 4.6e-05 22.9 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND88128.1 - 0.00013 21.6 6.7 0.00013 21.6 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND88128.1 - 0.0009 19.2 9.5 0.0009 19.2 6.6 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND88128.1 - 0.0021 17.7 2.7 0.0021 17.7 1.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KND88128.1 - 0.0098 15.9 5.5 0.0098 15.9 3.8 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KND88128.1 - 0.019 14.7 3.8 0.049 13.4 2.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HALZ PF02183.13 KND88128.1 - 0.03 14.0 1.4 0.075 12.7 1.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cor1 PF04803.7 KND88128.1 - 0.063 13.0 1.5 0.11 12.3 1.1 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region zf-Apc11 PF12861.2 KND88128.1 - 0.069 12.9 5.3 0.19 11.5 3.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CENP-F_leu_zip PF10473.4 KND88128.1 - 0.11 12.3 19.1 0.52 10.1 3.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 KND88128.1 - 0.26 11.2 7.4 0.26 11.2 2.9 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4164 PF13747.1 KND88128.1 - 2.3 8.3 13.9 0.076 13.1 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF4200 PF13863.1 KND88128.1 - 8.9 6.2 14.7 7.2 6.5 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 KND88128.1 - 9.8 6.2 14.3 9.8 6.2 2.8 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cpn60_TCP1 PF00118.19 KND88130.1 - 2.2e-145 485.0 3.0 2.7e-145 484.7 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RTA1 PF04479.8 KND88131.1 - 1.1e-10 41.4 0.1 1.2e-10 41.3 0.1 1.0 1 0 0 1 1 1 1 RTA1 like protein Rieske PF00355.21 KND88131.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.4 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain DUF2461 PF09365.5 KND88132.1 - 9.3e-66 221.2 0.1 1.2e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) HSP70 PF00012.15 KND88133.1 - 4.8e-268 890.0 15.7 5.5e-268 889.8 10.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND88133.1 - 3.4e-18 65.3 2.6 6e-17 61.2 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 KND88133.1 - 0.0017 17.2 0.4 0.075 11.8 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KND88133.1 - 0.0038 16.3 4.1 0.011 14.8 0.1 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KND88133.1 - 0.73 9.6 7.4 4.2 7.2 0.1 3.8 3 1 0 3 3 3 0 Cell division protein FtsA GTP_EFTU PF00009.22 KND88134.1 - 2.8e-49 167.1 0.0 5e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KND88134.1 - 1.2e-20 73.3 1.4 2.6e-20 72.3 1.0 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 KND88134.1 - 1.8e-08 34.3 0.1 6.1e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 KND88134.1 - 3.9e-08 33.3 0.0 1.5e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KND88134.1 - 4.6e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND88134.1 - 0.0062 17.0 1.1 0.053 14.0 0.0 2.9 3 1 0 3 3 3 1 Miro-like protein Arf PF00025.16 KND88134.1 - 0.045 12.9 0.0 8.8 5.5 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 KND88134.1 - 0.086 12.0 0.0 3.5 6.8 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KND88134.1 - 0.19 10.7 0.0 0.41 9.6 0.0 1.5 1 0 0 1 1 1 0 Septin Pyridox_oxidase PF01243.15 KND88136.1 - 0.0012 18.8 0.0 0.45 10.5 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 KND88136.1 - 0.0017 18.9 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KND88136.1 - 0.0021 18.1 0.0 0.2 11.8 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain CTP_transf_2 PF01467.21 KND88137.1 - 1.6e-28 99.7 0.0 2.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Exo_endo_phos PF03372.18 KND88139.1 - 8e-12 45.6 0.8 1.4e-11 44.8 0.2 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Fibritin_C PF07921.7 KND88139.1 - 0.052 13.4 0.1 18 5.3 0.0 2.9 2 0 0 2 2 2 0 Fibritin C-terminal region Exo_endo_phos_2 PF14529.1 KND88139.1 - 0.073 12.6 0.1 0.4 10.3 0.1 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF2422 PF10337.4 KND88140.1 - 3.8e-08 32.5 15.3 8.9e-06 24.7 0.9 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KND88140.1 - 4.1e-07 29.9 8.7 4.1e-07 29.9 6.0 3.6 2 2 2 4 4 4 2 Fusaric acid resistance protein-like ALMT PF11744.3 KND88140.1 - 0.17 10.4 3.1 0.092 11.3 0.2 1.9 2 1 0 2 2 2 0 Aluminium activated malate transporter ESSS PF10183.4 KND88141.1 - 3.6e-18 65.8 0.6 5e-18 65.4 0.4 1.4 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DASH_Duo1 PF08651.5 KND88142.1 - 2.1e-26 91.3 0.1 3.2e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF4355 PF14265.1 KND88142.1 - 0.19 11.6 6.0 0.32 10.9 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Radial_spoke_3 PF06098.6 KND88142.1 - 4.1 6.3 11.5 8 5.3 8.0 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 RNase_H2-Ydr279 PF09468.5 KND88143.1 - 1.9e-90 303.1 0.2 2.6e-90 302.7 0.1 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3340 PF11818.3 KND88143.1 - 0.042 13.7 4.9 0.092 12.6 3.4 1.5 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) TTL PF03133.10 KND88144.1 - 7.2e-53 179.4 0.0 1.1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KND88144.1 - 8.3e-45 152.5 0.0 1.6e-44 151.5 0.0 1.5 2 0 0 2 2 2 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KND88144.1 - 0.00089 18.1 0.0 0.0023 16.8 0.0 1.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KND88144.1 - 0.0023 17.6 0.1 0.43 10.2 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Hemopexin PF00045.14 KND88145.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Hemopexin SIR2 PF02146.12 KND88146.1 - 4.8e-59 199.0 0.0 7.4e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KND88146.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KND88146.1 - 0.037 13.7 0.2 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain E1-E2_ATPase PF00122.15 KND88147.1 - 1.8e-54 184.1 1.9 1.8e-54 184.1 1.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND88147.1 - 1.7e-39 135.2 4.8 1.7e-39 135.2 3.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND88147.1 - 5.9e-27 95.4 0.1 1.5e-25 90.8 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND88147.1 - 9e-19 67.2 0.0 1.9e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KND88147.1 - 1.7e-16 60.9 0.0 3.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND88147.1 - 1.6e-06 27.5 0.0 1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KND88147.1 - 1.4e-05 24.8 1.3 1.7e-05 24.5 0.3 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_4 PF01063.14 KND88148.1 - 5.9e-31 107.7 0.0 7.8e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 KND88149.1 - 1.4e-15 57.1 0.0 3.1e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88149.1 - 1.5e-07 30.7 0.0 6.2e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Med3 PF11593.3 KND88149.1 - 0.00067 19.0 1.6 0.0023 17.2 1.1 1.8 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal CN_hydrolase PF00795.17 KND88150.1 - 2.3e-26 92.2 0.1 3.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.17 KND88151.1 - 7.2e-31 107.2 0.0 1.4e-30 106.2 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 KND88152.1 - 7.7e-31 107.1 0.0 1.5e-30 106.1 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 HLH PF00010.21 KND88153.1 - 5.6e-16 57.9 0.0 1.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M24 PF00557.19 KND88154.1 - 2.3e-49 167.7 0.0 4e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KND88154.1 - 2.6e-34 117.4 0.1 4.5e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 KND88155.1 - 2e-41 140.6 0.0 4.9e-41 139.4 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KND88155.1 - 5.3e-24 83.6 0.8 9e-24 82.8 0.5 1.4 1 0 0 1 1 1 1 DBF zinc finger Aha1_N PF09229.6 KND88157.1 - 1.7e-39 134.7 0.1 2.5e-39 134.2 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KND88157.1 - 2.1e-18 66.6 1.3 5.7e-18 65.1 0.2 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 KND88157.1 - 0.0002 21.5 1.2 0.0067 16.6 0.1 2.2 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport SH3BGR PF04908.10 KND88157.1 - 0.0031 17.4 0.5 3 7.8 0.1 3.3 2 1 1 3 3 3 2 SH3-binding, glutamic acid-rich protein zf-DHHC PF01529.15 KND88158.1 - 6.7e-31 107.0 3.6 6.7e-31 107.0 2.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase PHO4 PF01384.15 KND88158.1 - 0.089 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family LRV_FeS PF05484.6 KND88158.1 - 0.25 10.9 3.6 0.5 9.9 2.5 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster Adeno_E1A PF02703.9 KND88158.1 - 3.7 6.8 7.1 5.8 6.2 4.9 1.2 1 0 0 1 1 1 0 Early E1A protein FtsX PF02687.16 KND88158.1 - 4.6 7.0 11.2 0.23 11.2 0.2 2.8 3 1 0 3 3 3 0 FtsX-like permease family Rap1_C PF11626.3 KND88159.1 - 2.4e-23 81.8 0.0 1.8e-22 78.9 0.0 2.5 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KND88159.1 - 1.2e-16 60.2 1.5 2.4e-16 59.3 0.2 2.2 3 0 0 3 3 3 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KND88159.1 - 3.2e-05 24.4 0.1 0.00027 21.4 0.0 2.6 3 0 0 3 3 3 1 Rap1, DNA-binding ARID PF01388.16 KND88159.1 - 0.00019 21.1 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Histone_HNS PF00816.16 KND88159.1 - 0.71 10.4 8.4 0.3 11.6 0.4 2.9 3 0 0 3 3 3 0 H-NS histone family Tubulin PF00091.20 KND88160.1 - 5.3e-70 235.5 0.0 9.5e-70 234.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KND88160.1 - 1.7e-48 163.8 0.1 2.6e-48 163.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Ribosomal_L6 PF00347.18 KND88160.1 - 5.2e-14 52.5 0.0 1.2e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein L6 Misat_Tub_SegII PF10644.4 KND88160.1 - 1.6e-05 24.8 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KND88160.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain FtsJ PF01728.14 KND88162.1 - 6.2e-60 202.2 0.0 8.4e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Sec7_N PF12783.2 KND88163.1 - 1.4e-38 131.9 2.9 1e-36 125.9 0.0 3.6 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KND88163.1 - 1.7e-06 27.4 0.1 4e-05 23.0 0.0 3.4 4 1 1 5 5 5 1 Domain of unknown function (DUF1981) DUF3384 PF11864.3 KND88163.1 - 0.00055 18.5 2.5 0.028 12.8 0.0 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3384) Pribosyltran_N PF13793.1 KND88164.1 - 2.2e-42 143.4 0.5 1.4e-41 140.8 0.1 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KND88164.1 - 1.2e-37 129.4 2.7 1.7e-28 99.5 0.7 3.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KND88164.1 - 1e-10 41.3 0.4 2.2e-10 40.3 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KND88164.1 - 0.001 18.2 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 KND88164.1 - 0.0089 15.7 0.4 0.019 14.6 0.3 1.5 1 0 0 1 1 1 1 Chlorosome envelope protein C Flavoprotein PF02441.14 KND88165.1 - 3.9e-15 55.6 0.0 7.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein UQ_con PF00179.21 KND88167.1 - 1.9e-16 59.7 0.0 2.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KND88167.1 - 0.036 13.9 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain Band_7 PF01145.20 KND88168.1 - 1.8e-30 106.1 0.7 3.6e-30 105.2 0.5 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KND88168.1 - 0.039 13.4 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Pox_A11 PF05061.8 KND88168.1 - 0.11 11.5 0.3 0.21 10.6 0.2 1.5 1 0 0 1 1 1 0 Poxvirus A11 Protein KH_1 PF00013.24 KND88169.1 - 1.7e-86 283.7 25.3 3e-13 49.1 0.1 13.4 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 KND88169.1 - 1.4e-58 193.6 24.1 1.2e-09 37.5 0.3 12.6 13 0 0 13 13 13 8 KH domain KH_2 PF07650.12 KND88169.1 - 2.6e-10 39.7 22.5 0.037 13.5 0.2 7.7 6 1 0 7 7 7 4 KH domain SLS PF14611.1 KND88169.1 - 1.1e-09 38.0 6.6 0.0016 17.9 0.0 6.1 5 2 3 8 8 8 3 Mitochondrial inner-membrane-bound regulator BON PF04972.12 KND88169.1 - 0.0025 17.5 3.4 1.2 8.9 0.1 3.8 3 0 0 3 3 3 2 BON domain KH_4 PF13083.1 KND88169.1 - 0.015 14.9 7.3 3.5 7.3 0.0 5.1 6 0 0 6 6 6 0 KH domain DUF1699 PF08004.6 KND88169.1 - 0.17 11.4 0.3 3.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Pkinase PF00069.20 KND88170.1 - 1.6e-70 237.2 0.0 2.3e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88170.1 - 2.5e-46 157.8 0.0 4.2e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KND88170.1 - 1.5e-17 63.7 1.6 7.3e-17 61.5 0.0 3.1 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 KND88170.1 - 1.2e-07 30.9 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND88170.1 - 0.024 14.3 0.7 0.099 12.3 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 KND88170.1 - 0.13 11.5 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain adh_short PF00106.20 KND88171.1 - 3.7e-32 111.5 2.4 5.3e-32 111.0 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND88171.1 - 6.3e-27 94.8 0.3 8.3e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND88171.1 - 2.6e-14 53.2 0.3 3.9e-14 52.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND88171.1 - 1.2e-06 28.2 0.3 2.3e-06 27.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 KND88171.1 - 0.00049 19.7 0.1 0.0013 18.3 0.1 1.7 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 KND88171.1 - 0.014 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Oxidored_nitro PF00148.14 KND88171.1 - 0.04 12.5 0.0 0.079 11.5 0.0 1.5 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Metallophos_2 PF12850.2 KND88172.1 - 9.8e-08 31.9 0.0 2.2e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND88172.1 - 2.3e-06 27.1 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Miro PF08477.8 KND88172.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein PRP21_like_P PF12230.3 KND88172.1 - 0.018 14.5 0.4 0.027 14.0 0.3 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein ARID PF01388.16 KND88173.1 - 8e-16 57.6 0.0 2.1e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Arm PF00514.18 KND88173.1 - 0.97 9.3 3.1 9.5 6.2 0.0 3.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF605 PF04652.11 KND88173.1 - 2.7 7.3 15.9 4.6 6.5 11.0 1.2 1 0 0 1 1 1 0 Vta1 like Dna2 PF08696.6 KND88175.1 - 2e-67 226.5 0.1 2e-67 226.5 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 KND88175.1 - 2.7e-52 177.0 0.0 4.7e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND88175.1 - 1.6e-38 132.6 0.4 2.8e-18 66.3 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KND88175.1 - 1.6e-14 53.9 0.0 4.3e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND88175.1 - 7.6e-12 44.8 1.4 1e-10 41.1 0.2 3.0 3 0 0 3 3 3 1 Part of AAA domain Cas_Cas4 PF01930.12 KND88175.1 - 4.8e-09 36.3 0.1 9.9e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 KND88175.1 - 1.9e-06 27.4 0.0 4.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KND88175.1 - 6.6e-06 25.8 0.8 0.22 10.9 0.1 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KND88175.1 - 2.8e-05 23.8 0.0 6.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Helicase MobB PF03205.9 KND88175.1 - 4.9e-05 23.0 0.2 0.00023 20.8 0.1 2.2 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KND88175.1 - 0.0012 18.3 0.1 0.0023 17.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.9 KND88175.1 - 0.0012 17.8 0.0 0.055 12.4 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase CbiA PF01656.18 KND88175.1 - 0.003 16.9 0.1 0.014 14.7 0.1 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.16 KND88175.1 - 0.0038 16.5 0.0 0.0083 15.4 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SE PF00437.15 KND88175.1 - 0.0085 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 KND88175.1 - 0.013 15.4 0.1 0.044 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain AAA_25 PF13481.1 KND88175.1 - 0.015 14.6 0.0 0.066 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND88175.1 - 0.027 14.6 0.0 0.3 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KND88175.1 - 0.034 13.9 0.2 0.097 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 KND88175.1 - 0.1 13.0 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein NTPase_1 PF03266.10 KND88175.1 - 0.1 12.2 0.2 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 KND88175.1 - 0.11 11.2 1.0 0.15 10.7 0.0 1.6 2 0 0 2 2 2 0 ArgK protein DUF2075 PF09848.4 KND88175.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4102 PF13356.1 KND88176.1 - 0.1 12.4 1.0 0.4 10.5 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4102) UCR_hinge PF02320.11 KND88177.1 - 2.4e-28 97.8 7.7 5e-28 96.8 5.4 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 KND88177.1 - 0.28 9.1 10.0 0.31 9.0 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 KND88177.1 - 4.8 5.1 8.6 5.1 5.0 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP70 PF00012.15 KND88177.1 - 6.1 4.6 11.0 7 4.4 7.7 1.0 1 0 0 1 1 1 0 Hsp70 protein SDA1 PF05285.7 KND88177.1 - 7.4 5.7 19.4 8 5.6 13.5 1.0 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 KND88177.1 - 7.5 4.1 9.4 7.7 4.0 6.5 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3c_N PF05470.7 KND88177.1 - 8.8 4.2 12.1 9.6 4.1 8.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1510 PF07423.6 KND88177.1 - 9.4 5.5 19.3 12 5.2 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MFS_1 PF07690.11 KND88178.1 - 6.7e-24 84.2 38.7 4.2e-22 78.3 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_psq PF05225.11 KND88178.1 - 0.16 11.5 0.4 0.35 10.4 0.3 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DND1_DSRM PF14709.1 KND88179.1 - 0.00016 21.8 0.0 0.0003 21.0 0.0 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KND88179.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Potassium_chann PF11404.3 KND88179.1 - 2.3 8.0 7.4 5 7.0 5.1 1.6 1 0 0 1 1 1 0 Potassium voltage-gated channel NTP_transferase PF00483.18 KND88180.1 - 4e-48 163.8 0.0 9.1e-48 162.7 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KND88180.1 - 1.2e-12 46.7 9.5 8.7e-10 37.6 1.0 3.8 2 2 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KND88180.1 - 2.9e-10 40.4 0.0 4.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KND88180.1 - 1.7e-08 33.8 6.1 4.2e-07 29.4 1.2 3.2 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 KND88180.1 - 0.0089 15.6 0.0 0.022 14.3 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase RNA_ligase PF09414.5 KND88181.1 - 8.5e-14 51.7 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 RNA ligase RTA1 PF04479.8 KND88182.1 - 3.4e-10 39.7 3.4 5e-10 39.2 2.4 1.3 1 0 0 1 1 1 1 RTA1 like protein DPM2 PF07297.7 KND88182.1 - 0.6 10.4 7.7 77 3.6 5.3 2.3 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-CHY PF05495.7 KND88184.1 - 3.2e-16 59.2 22.5 3.7e-15 55.8 8.5 3.3 3 0 0 3 3 3 2 CHY zinc finger RWD PF05773.17 KND88184.1 - 0.0021 17.9 0.1 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 RWD domain Mu-like_Com PF10122.4 KND88184.1 - 0.0024 16.9 0.3 0.0024 16.9 0.2 2.3 2 0 0 2 2 2 1 Mu-like prophage protein Com AMP-binding PF00501.23 KND88185.1 - 7e-75 251.9 0.0 9.4e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PAN_3 PF08277.7 KND88185.1 - 0.2 11.3 1.7 0.43 10.2 0.7 1.9 1 1 0 1 1 1 0 PAN-like domain DUF3295 PF11702.3 KND88186.1 - 3.5e-126 422.2 38.3 3.5e-126 422.2 26.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KND88186.1 - 2.2e-12 46.3 0.9 4.6e-12 45.2 0.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) VHS PF00790.14 KND88187.1 - 3.2e-41 140.2 2.2 2e-40 137.6 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KND88187.1 - 8.8e-16 57.5 3.1 1.6e-15 56.7 2.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-DHHC PF01529.15 KND88187.1 - 0.00014 21.3 0.1 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase NTPase_I-T PF01931.13 KND88187.1 - 0.0019 17.9 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF84 UIM PF02809.15 KND88187.1 - 0.0094 15.4 0.7 0.0094 15.4 0.5 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif Ribosomal_S30AE PF02482.14 KND88187.1 - 0.021 15.2 0.5 0.065 13.6 0.4 1.8 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein C1_1 PF00130.17 KND88187.1 - 0.062 13.0 4.7 0.11 12.2 3.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KND88187.1 - 0.077 12.8 2.1 0.17 11.7 1.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger UCH PF00443.24 KND88188.1 - 1.8e-44 151.8 0.0 2.7e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND88188.1 - 1.8e-18 67.0 0.0 2.7e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KND88188.1 - 3.5e-08 33.7 0.0 8.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Lactonase PF10282.4 KND88189.1 - 1.4e-13 50.7 0.0 3.3e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 KND88190.1 - 1.1e-47 161.7 0.0 1.4e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KND88190.1 - 1.6e-12 47.2 0.1 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Methyltransf_6 PF03737.10 KND88191.1 - 4.2e-18 65.6 0.1 5.8e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase WWbp PF10349.4 KND88192.1 - 5.5e-15 56.2 4.9 8.6e-15 55.6 3.4 1.3 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KND88192.1 - 0.00086 19.0 0.0 0.0079 15.9 0.0 2.1 1 1 1 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 KND88192.1 - 0.026 14.7 0.0 0.061 13.5 0.0 1.5 1 1 1 2 2 2 0 Bacterial PH domain GRAM PF02893.15 KND88192.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Glyoxalase PF00903.20 KND88194.1 - 1.8e-39 134.6 0.1 9.6e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KND88194.1 - 4.1e-33 114.2 0.0 5.4e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KND88194.1 - 1.9e-17 63.2 0.1 9.9e-07 28.7 0.0 4.1 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KND88194.1 - 1.4e-05 25.0 0.0 0.44 10.4 0.0 3.6 1 1 2 3 3 3 3 Glyoxalase-like domain 2-Hacid_dh_C PF02826.14 KND88195.1 - 6.3e-54 181.8 0.1 1.1e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND88195.1 - 1.8e-33 114.8 0.3 3.4e-33 113.9 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 KND88195.1 - 0.00043 19.7 0.4 0.015 14.7 0.0 2.8 2 0 0 2 2 2 1 ACT domain AlaDh_PNT_C PF01262.16 KND88195.1 - 0.0035 16.9 0.2 0.0078 15.7 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 KND88195.1 - 0.0053 17.0 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain DUF21 PF01595.15 KND88196.1 - 5.2e-33 113.8 0.3 7.4e-33 113.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KND88196.1 - 2.7e-07 30.2 0.6 0.006 16.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.20 KND88197.1 - 1.9e-09 37.0 0.0 3.9e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain EF-hand_9 PF14658.1 KND88197.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Sec63 PF02889.11 KND88199.1 - 4.4e-27 95.1 0.0 5e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.1 KND88199.1 - 0.0025 17.9 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Acetyltransf_1 PF00583.19 KND88201.1 - 1.1e-08 34.9 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND88201.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND88201.1 - 0.00014 21.5 0.0 0.00032 20.3 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KND88201.1 - 0.00042 20.1 0.1 0.00098 18.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND88201.1 - 0.048 13.7 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND88202.1 - 1.3e-06 28.2 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND88202.1 - 1.6e-06 28.1 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND88202.1 - 7.2e-06 26.1 0.1 3.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND88202.1 - 0.00021 21.1 0.0 0.00051 19.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND88202.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 KND88202.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Tyrosinase PF00264.15 KND88203.1 - 3.3e-34 118.9 1.4 1.5e-28 100.5 0.3 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase zf-primase PF09329.6 KND88204.1 - 2.4e-17 62.2 1.2 4.3e-17 61.4 0.8 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 KND88204.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Inositol_P PF00459.20 KND88207.1 - 2.5e-53 181.1 0.9 3.9e-53 180.5 0.6 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family DUF2946 PF11162.3 KND88207.1 - 0.69 10.1 3.4 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) ABC_tran PF00005.22 KND88208.1 - 4e-47 159.9 0.3 3.7e-22 79.1 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KND88208.1 - 2.4e-19 68.9 8.6 2.4e-19 68.9 5.9 3.3 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KND88208.1 - 3.8e-17 63.2 1.4 7.4e-05 22.8 0.0 4.6 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 KND88208.1 - 6.7e-10 38.5 3.8 0.006 15.8 0.0 4.7 5 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KND88208.1 - 5.9e-09 36.7 0.8 0.01 16.6 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_15 PF13175.1 KND88208.1 - 1.1e-06 28.0 2.9 0.18 10.8 0.0 3.9 4 1 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 KND88208.1 - 2.5e-06 27.9 0.0 0.015 15.7 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KND88208.1 - 3e-06 27.1 0.0 0.026 14.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KND88208.1 - 4.6e-06 26.0 0.2 0.087 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 KND88208.1 - 1.1e-05 25.7 2.1 0.19 12.0 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.1 KND88208.1 - 3.1e-05 24.0 2.0 0.025 14.5 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KND88208.1 - 3.1e-05 23.2 0.0 0.072 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND88208.1 - 3.2e-05 24.0 0.2 0.76 9.9 0.2 3.4 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 KND88208.1 - 4.4e-05 23.2 0.0 0.23 11.1 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KND88208.1 - 8.9e-05 22.4 0.3 0.36 10.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KND88208.1 - 0.00012 21.9 0.1 0.46 10.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 KND88208.1 - 0.00013 22.1 0.1 0.37 10.9 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KND88208.1 - 0.00015 22.1 14.8 0.0064 16.8 0.0 4.3 5 0 0 5 5 4 2 AAA domain ArgK PF03308.11 KND88208.1 - 0.00029 19.7 0.2 0.64 8.7 0.0 2.7 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 KND88208.1 - 0.00038 20.3 0.9 0.42 10.5 0.4 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KND88208.1 - 0.00052 19.7 0.1 1.6 8.3 0.0 2.9 2 0 0 2 2 2 2 NACHT domain NTPase_1 PF03266.10 KND88208.1 - 0.00098 18.8 0.2 0.17 11.5 0.1 2.8 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.18 KND88208.1 - 0.0012 18.6 2.7 1.4 8.7 0.0 3.7 4 0 0 4 4 4 1 Dynamin family ATP-synt_ab PF00006.20 KND88208.1 - 0.0018 17.8 0.0 0.57 9.6 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 KND88208.1 - 0.0022 17.8 0.0 1.4 8.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KND88208.1 - 0.0035 16.8 0.0 2 7.8 0.0 3.3 4 0 0 4 4 4 1 AAA-like domain T2SE PF00437.15 KND88208.1 - 0.0086 15.0 0.0 0.15 10.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 KND88208.1 - 0.013 14.9 1.2 1.3 8.3 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KND88208.1 - 0.013 15.6 0.1 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KND88208.1 - 0.014 14.2 0.0 4.3 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 KND88208.1 - 0.023 14.4 0.3 6 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KND88208.1 - 0.036 13.6 0.2 6.9 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KND88208.1 - 0.041 13.3 0.2 9.2 5.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KND88208.1 - 0.18 11.1 2.3 2.3 7.6 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Arf PF00025.16 KND88208.1 - 0.19 10.9 1.4 1.7 7.8 0.0 2.6 3 0 0 3 3 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND88208.1 - 1.4 8.2 4.0 6.8 6.0 0.0 3.2 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Spermine_synth PF01564.12 KND88209.1 - 3.9e-06 25.9 0.0 5.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KND88209.1 - 5.7e-06 26.3 0.2 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND88209.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 KND88210.1 - 4.2e-24 84.8 0.0 6.8e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88210.1 - 0.041 13.8 5.9 0.082 12.8 4.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transf_2 PF01909.18 KND88210.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase domain Pyridox_ox_2 PF12900.2 KND88212.1 - 4.3e-39 133.5 0.0 5.9e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans_2 PF11951.3 KND88214.1 - 4.7e-11 41.9 0.0 9.7e-11 40.8 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain HTH_31 PF13560.1 KND88215.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Evr1_Alr PF04777.8 KND88216.1 - 0.00048 19.9 0.2 0.00089 19.1 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family MFS_1 PF07690.11 KND88218.1 - 3e-22 78.8 28.1 3.1e-15 55.7 8.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4083 PF13314.1 KND88218.1 - 0.12 12.1 0.3 0.51 10.2 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ESSS PF10183.4 KND88218.1 - 2.4 8.5 7.1 3.7 7.9 1.5 3.0 1 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) F_bP_aldolase PF01116.15 KND88220.1 - 4.9e-88 294.9 0.0 5.4e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Toxin_51 PF15531.1 KND88220.1 - 0.054 13.2 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Putative toxin 51 Dabb PF07876.7 KND88221.1 - 5.9e-12 45.8 0.4 9.6e-12 45.1 0.2 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Ldh_2 PF02615.9 KND88222.1 - 5.7e-89 298.1 0.1 6.8e-89 297.8 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Methyltransf_6 PF03737.10 KND88223.1 - 1.4e-28 99.6 0.0 2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase AMP-binding PF00501.23 KND88227.1 - 2.3e-78 263.4 0.0 2.8e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND88227.1 - 1.5e-14 54.6 0.5 2.8e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-RAG1 PF10426.4 KND88227.1 - 1 9.3 2.8 0.74 9.8 0.3 2.0 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Pyr_redox_3 PF13738.1 KND88228.1 - 3e-20 73.1 0.0 1.7e-19 70.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.7 KND88228.1 - 3.2e-18 66.0 0.0 1.2e-17 64.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND88228.1 - 2.1e-12 47.0 0.0 4.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND88228.1 - 2.8e-10 39.9 0.0 8e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND88228.1 - 1.8e-09 37.9 0.0 4.9e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FMO-like PF00743.14 KND88228.1 - 1.3e-08 33.4 0.1 2.7e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Ubie_methyltran PF01209.13 KND88228.1 - 1.5e-07 30.7 0.0 3.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KND88228.1 - 2.1e-07 31.4 0.0 2.6e-06 27.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND88228.1 - 6.9e-07 29.5 0.0 2e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_8 PF13450.1 KND88228.1 - 1e-06 28.6 0.0 1.5e-05 24.8 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Methyltransf_16 PF10294.4 KND88228.1 - 3.3e-05 23.4 0.0 6.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Pyr_redox_2 PF07992.9 KND88228.1 - 0.00024 21.0 0.0 0.0029 17.5 0.0 2.9 3 2 1 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase PCMT PF01135.14 KND88228.1 - 0.0078 15.7 0.0 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KND88228.1 - 0.011 15.7 0.0 0.056 13.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain K_oxygenase PF13434.1 KND88228.1 - 0.02 13.7 0.0 0.049 12.5 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 KND88228.1 - 0.031 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DREV PF05219.7 KND88228.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 KND88228.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Thi4 PF01946.12 KND88228.1 - 0.17 10.9 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Zn_clus PF00172.13 KND88229.1 - 9e-08 31.9 6.8 1.9e-07 30.8 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND88229.1 - 1.7e-05 23.5 0.1 2.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AhpC-TSA PF00578.16 KND88230.1 - 2.3e-31 108.0 0.0 3.6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND88230.1 - 1.1e-11 44.4 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KND88230.1 - 7.2e-11 41.5 0.1 1.4e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DIOX_N PF14226.1 KND88231.1 - 8e-20 71.5 0.0 8.9e-17 61.6 0.0 2.4 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND88231.1 - 4e-17 62.3 0.0 7.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KND88232.1 - 7.8e-24 84.0 75.3 7.4e-22 77.5 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TrbE PF11100.3 KND88232.1 - 0.029 14.2 1.8 0.08 12.8 0.2 2.6 2 0 0 2 2 2 0 Conjugal transfer protein TrbE DUF2407_C PF13373.1 KND88232.1 - 3.8 7.4 8.7 0.31 10.9 0.7 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain Flocculin_t3 PF13928.1 KND88233.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.2 2 0 0 2 2 2 0 Flocculin type 3 repeat Amidase PF01425.16 KND88234.1 - 6.7e-98 328.4 0.0 8e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Amidase ADH_N PF08240.7 KND88235.1 - 3.9e-11 42.6 0.0 8.1e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND88235.1 - 6e-10 38.7 0.2 1.3e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_transf_90 PF05686.7 KND88236.1 - 9.6e-12 44.2 0.5 7.8e-10 37.9 0.2 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Fungal_trans PF04082.13 KND88237.1 - 1.6e-16 60.0 0.7 2.2e-16 59.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88238.1 - 3.2e-10 39.7 7.6 4.3e-10 39.3 5.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSSP PF03940.8 KND88238.1 - 0.86 9.0 5.7 1.4 8.3 3.9 1.4 1 0 0 1 1 1 0 Male specific sperm protein Dickkopf_N PF04706.7 KND88238.1 - 6.7 6.9 11.9 11 6.2 8.2 1.5 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ketoacyl-synt PF00109.21 KND88239.1 - 4.2e-69 232.8 0.2 9.1e-69 231.7 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KND88239.1 - 7.5e-30 103.2 0.0 1.7e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KND88239.1 - 1.9e-28 99.7 0.0 3.7e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 KND88239.1 - 3e-25 88.5 0.0 1.7e-24 86.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KND88239.1 - 7.2e-12 45.4 0.1 1.7e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KND88239.1 - 8e-12 45.4 0.0 2.7e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KND88239.1 - 3.5e-06 26.2 0.1 6.5e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 KND88239.1 - 3e-05 23.6 0.0 6.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND88239.1 - 0.00012 21.8 0.0 0.00038 20.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KND88239.1 - 0.00022 21.2 0.0 0.00061 19.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.7 KND88239.1 - 0.0017 18.8 0.0 0.0061 17.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KND88239.1 - 0.0034 16.8 0.0 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KND88239.1 - 0.0099 15.5 0.0 0.034 13.8 0.0 1.9 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND88239.1 - 0.041 12.7 0.0 0.41 9.4 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 KND88239.1 - 0.068 13.0 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KND88239.1 - 0.077 11.8 0.0 3.3 6.5 0.0 2.5 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1033 PF06279.6 KND88239.1 - 0.16 11.8 2.0 0.33 10.7 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) RrnaAD PF00398.15 KND88239.1 - 0.2 10.6 0.0 0.38 9.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_3 PF01494.14 KND88240.1 - 1.4e-17 63.8 9.3 1e-16 60.9 5.8 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND88240.1 - 0.0088 16.0 2.3 0.021 14.8 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND88240.1 - 0.017 15.5 2.4 0.017 15.5 1.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KND88240.1 - 0.029 13.1 0.0 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.19 KND88240.1 - 0.039 12.8 6.1 0.047 12.6 3.3 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.17 KND88241.1 - 7e-109 364.2 1.5 2.5e-77 260.1 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DHDPS PF00701.17 KND88242.1 - 5.6e-63 212.2 0.0 6.3e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CutC PF03932.9 KND88242.1 - 0.07 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 CutC family PorB PF11565.3 KND88242.1 - 0.15 12.3 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Alpha helical Porin B ATP-grasp_4 PF13535.1 KND88243.1 - 1.3e-13 51.0 0.0 4.7e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KND88243.1 - 1.6e-10 40.6 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KND88243.1 - 0.0077 16.1 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KND88243.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KND88243.1 - 0.025 13.3 0.0 0.17 10.5 0.0 2.2 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MFS_1 PF07690.11 KND88244.1 - 7.3e-08 31.5 3.2 1.1e-07 30.8 2.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.8 KND88244.1 - 8e-05 22.0 0.3 0.0001 21.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) TRI12 PF06609.8 KND88244.1 - 0.00038 18.7 0.7 0.00042 18.6 0.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4079 PF13301.1 KND88244.1 - 0.0018 18.3 1.8 0.25 11.3 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) AA_permease PF00324.16 KND88244.1 - 0.021 13.1 0.3 0.025 12.9 0.2 1.0 1 0 0 1 1 1 0 Amino acid permease COX15-CtaA PF02628.10 KND88244.1 - 0.051 12.4 0.2 0.062 12.1 0.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF2613 PF11021.3 KND88244.1 - 0.16 11.7 0.5 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF1206 PF06724.6 KND88244.1 - 1.1 9.0 3.9 3.4 7.4 2.2 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) MFS_1 PF07690.11 KND88245.1 - 0.073 11.7 6.4 0.45 9.1 3.8 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily ABC2_membrane_4 PF12730.2 KND88245.1 - 0.27 10.3 5.1 0.089 11.9 1.3 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein PMT_2 PF13231.1 KND88245.1 - 1.1 9.1 7.9 0.089 12.6 2.1 1.7 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Chromate_transp PF02417.10 KND88245.1 - 1.6 8.3 7.9 0.59 9.7 1.8 2.2 1 1 1 2 2 2 0 Chromate transporter MFS_1 PF07690.11 KND88246.1 - 1.2e-27 96.6 22.6 1.2e-27 96.6 15.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KND88246.1 - 0.019 13.0 3.9 0.72 7.8 0.5 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1049 PF06305.6 KND88246.1 - 0.48 9.9 12.7 1.4 8.4 0.3 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) DUF3959 PF13105.1 KND88246.1 - 0.59 9.4 3.0 0.44 9.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Methyltransf_2 PF00891.13 KND88247.1 - 4e-26 91.6 0.0 1.1e-24 86.9 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase GST_C PF00043.20 KND88248.1 - 7.1e-11 41.9 0.0 1.6e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND88248.1 - 2.4e-08 33.7 0.0 5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KND88248.1 - 2.1e-06 27.7 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KND88248.1 - 0.00055 20.3 0.0 0.002 18.5 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_23 PF13489.1 KND88249.1 - 0.00038 20.2 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1772 PF08592.6 KND88250.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) APH PF01636.18 KND88251.1 - 3.1e-17 63.1 0.1 5.3e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88251.1 - 0.0042 16.6 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PIG-S PF10510.4 KND88252.1 - 9.1e-134 446.9 0.0 1.2e-133 446.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Abhydrolase_5 PF12695.2 KND88252.1 - 8.7e-07 28.8 0.0 3.3e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KND88252.1 - 0.00097 18.6 0.2 0.0024 17.3 0.1 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KND88252.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KND88252.1 - 0.033 13.4 0.3 0.63 9.2 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family F-box PF00646.28 KND88253.1 - 0.02 14.5 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 F-box domain Kelch_3 PF13415.1 KND88254.1 - 4.5e-19 68.0 3.3 2.7e-10 40.1 0.0 6.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KND88254.1 - 5.5e-16 58.0 0.0 2e-06 27.4 0.0 5.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KND88254.1 - 3.4e-10 39.6 2.6 0.011 15.8 0.0 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KND88254.1 - 3.8e-10 39.4 3.8 0.0025 17.7 0.0 4.2 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 KND88254.1 - 5e-09 35.5 0.0 0.035 13.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 KND88254.1 - 5.2e-09 35.5 0.1 0.00028 20.5 0.0 4.4 5 0 0 5 5 5 2 Kelch motif BTB PF00651.26 KND88254.1 - 0.023 14.6 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.23 KND88255.1 - 1.2e-74 251.1 0.0 1.7e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND88255.1 - 2.8e-08 34.5 0.3 7.2e-08 33.2 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 KND88256.1 - 1.1e-10 41.8 0.3 2e-10 40.9 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND88256.1 - 1.1e-08 34.9 0.0 4.7e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND88256.1 - 0.00045 19.8 1.2 0.012 15.1 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND88256.1 - 0.0016 17.6 0.1 0.0054 15.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 KND88256.1 - 0.0031 16.9 0.0 0.015 14.7 0.0 2.1 2 1 0 2 2 2 1 Putative esterase DLH PF01738.13 KND88256.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 KND88256.1 - 0.13 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.23 KND88257.1 - 1.3e-77 260.9 0.0 3e-77 259.7 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KND88257.1 - 2.4e-70 236.9 0.0 4.3e-70 236.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KND88257.1 - 4.1e-53 179.7 0.2 4.6e-52 176.3 0.0 2.7 2 0 0 2 2 2 1 KR domain Condensation PF00668.15 KND88257.1 - 3.3e-49 167.3 0.7 5.8e-49 166.5 0.5 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KND88257.1 - 2.2e-48 164.9 0.0 4.3e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KND88257.1 - 3.9e-45 153.7 1.8 1.5e-42 145.3 0.0 3.7 4 0 0 4 4 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KND88257.1 - 5.5e-45 154.0 0.0 1.3e-44 152.8 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KND88257.1 - 1.6e-36 125.4 0.0 4.7e-36 123.9 0.0 1.9 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KND88257.1 - 4.4e-31 107.1 0.0 1.9e-30 105.1 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KND88257.1 - 3.9e-17 62.2 2.6 1.4e-10 41.2 0.1 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.16 KND88257.1 - 1.4e-13 50.8 0.0 1.9e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KND88257.1 - 2.3e-10 40.6 0.1 1.4e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 KND88257.1 - 2.2e-06 26.6 0.0 0.00029 19.6 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KND88257.1 - 3.8e-05 24.5 0.1 0.00022 22.1 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Methyltransf_18 PF12847.2 KND88257.1 - 0.00014 22.3 0.1 0.0015 19.0 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND88257.1 - 0.0014 19.0 0.0 0.0045 17.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KND88257.1 - 0.0026 16.7 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 KND88257.1 - 0.02 15.3 0.0 0.086 13.3 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KND88257.1 - 0.084 12.5 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 KND88257.1 - 0.16 10.8 0.0 8.6 5.1 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AATase PF07247.7 KND88257.1 - 2.1 6.7 0.1 4.1 5.8 0.1 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase PIF1 PF05970.9 KND88258.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase APH PF01636.18 KND88259.1 - 1.9e-14 53.9 0.0 3.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_5 PF12695.2 KND88259.1 - 5.6e-06 26.1 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND88259.1 - 3.4e-05 23.8 1.3 5.8e-05 23.0 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KND88259.1 - 0.0042 15.6 0.0 0.0067 14.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Choline_kinase PF01633.15 KND88259.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Abhydrolase_3 PF07859.8 KND88259.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold EcKinase PF02958.15 KND88259.1 - 0.22 10.6 0.0 0.4 9.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 KND88261.1 - 3.5e-12 46.5 0.0 2e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88261.1 - 0.0045 16.5 0.8 0.026 14.1 0.1 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase MFS_1 PF07690.11 KND88262.1 - 6.7e-38 130.3 66.0 2.7e-37 128.2 32.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KND88262.1 - 1.1e-17 63.5 14.7 2.3e-17 62.4 10.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KND88262.1 - 4.9e-09 35.2 15.5 4.9e-09 35.2 10.8 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3336 PF11815.3 KND88263.1 - 3.8e-42 143.2 0.8 7.2e-42 142.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KND88263.1 - 1.2e-23 84.1 0.0 2.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3509 PF12021.3 KND88263.1 - 0.062 13.0 0.3 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Chromo PF00385.19 KND88266.1 - 1.1e-09 37.7 3.2 7.2e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain MFS_1 PF07690.11 KND88267.1 - 8.1e-31 107.0 36.1 1.4e-30 106.2 25.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily APH PF01636.18 KND88267.1 - 3.7e-09 36.6 1.1 3.7e-09 36.6 0.7 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88267.1 - 0.0053 16.3 0.3 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ketoacyl-synt PF00109.21 KND88269.1 - 2.7e-76 256.4 0.0 5.8e-76 255.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND88269.1 - 3.6e-50 171.0 0.0 1.7e-48 165.5 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KND88269.1 - 1.5e-32 111.9 0.3 3.4e-32 110.7 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KND88269.1 - 3.8e-14 52.6 1.5 9.2e-14 51.4 1.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 KND88269.1 - 1.1e-13 51.0 0.0 3.3e-13 49.4 0.0 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KND88269.1 - 1.6e-05 24.0 0.0 3.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain EthD PF07110.6 KND88270.1 - 4.4e-19 69.2 2.2 5.4e-19 68.9 1.5 1.1 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 KND88271.1 - 8.7e-37 126.6 52.2 1.5e-34 119.2 32.5 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND88271.1 - 0.00038 19.1 43.4 0.00096 17.8 5.0 3.9 2 2 1 3 3 3 2 Sugar (and other) transporter Cu-oxidase_2 PF07731.9 KND88272.1 - 6.4e-11 41.9 0.2 7e-11 41.7 0.2 1.1 1 0 0 1 1 1 1 Multicopper oxidase Methyltransf_12 PF08242.7 KND88273.1 - 5.1e-14 52.5 0.0 8.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND88273.1 - 2.2e-10 40.5 0.0 7.2e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KND88273.1 - 2.8e-08 33.8 0.0 6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 KND88273.1 - 1.2e-05 25.5 0.0 2.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND88273.1 - 6.3e-05 23.3 0.0 0.00016 22.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND88273.1 - 0.00064 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND88273.1 - 0.0017 18.9 0.0 0.0038 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND88273.1 - 0.0034 17.3 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3494 PF11999.3 KND88274.1 - 4.7e-58 196.2 16.7 4.7e-58 196.2 11.6 4.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3494) Caps_synth PF05704.7 KND88275.1 - 1.3e-19 70.4 0.1 2.4e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KND88275.1 - 9.3e-07 29.1 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Aminotran_3 PF00202.16 KND88276.1 - 2e-85 286.6 0.0 2.4e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Nif11 PF07862.6 KND88276.1 - 0.025 14.5 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Epimerase PF01370.16 KND88277.1 - 6.7e-08 32.2 0.0 6.6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND88277.1 - 1.8e-05 24.1 0.0 7e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KND88277.1 - 0.00026 19.8 0.0 0.00038 19.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND88277.1 - 0.0014 18.6 0.1 0.0053 16.7 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND88277.1 - 0.003 16.5 0.0 0.0099 14.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Aldedh PF00171.17 KND88278.1 - 2.9e-179 596.2 0.1 3.3e-179 596.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aa_trans PF01490.13 KND88279.1 - 1.1e-27 96.6 23.2 4.6e-21 74.7 7.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein SIR2 PF02146.12 KND88281.1 - 2.6e-20 72.8 0.1 3.5e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Sir2 family Pro_racemase PF05544.6 KND88282.1 - 1e-113 379.5 0.0 1.1e-113 379.3 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 KND88282.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Fic PF02661.13 KND88283.1 - 2.7e-07 31.1 0.2 1.4e-06 28.9 0.1 1.9 2 0 0 2 2 2 1 Fic/DOC family HSP33 PF01430.14 KND88283.1 - 0.033 13.3 0.1 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Hsp33 protein GSIII_N PF12437.3 KND88283.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.3 1 1 0 1 1 1 0 Glutamine synthetase type III N terminal Zn_clus PF00172.13 KND88284.1 - 5.7e-09 35.7 10.5 9.1e-09 35.0 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND88284.1 - 0.004 16.0 0.1 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.12 KND88285.1 - 4.7e-107 357.3 0.3 6.7e-107 356.8 0.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KND88285.1 - 3e-41 140.9 2.6 4.6e-41 140.3 1.8 1.3 1 0 0 1 1 1 1 DAK2 domain PhyH PF05721.8 KND88286.1 - 2.8e-20 73.2 0.0 3.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KND88286.1 - 0.0083 14.6 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_34 PF05637.7 KND88288.1 - 1e-13 51.3 0.1 4.1e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KND88288.1 - 0.00023 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Ferric_reduct PF01794.14 KND88289.1 - 2.3e-18 66.4 11.3 5e-18 65.3 7.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KND88289.1 - 1.7e-05 24.8 0.2 0.14 12.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KND88289.1 - 1.7e-05 25.3 0.1 4.9e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 KND88289.1 - 2.7e-05 23.9 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain CFEM PF05730.6 KND88289.1 - 0.43 10.4 2.7 0.47 10.3 0.8 1.8 1 1 0 1 1 1 0 CFEM domain Dabb PF07876.7 KND88290.1 - 1.1e-24 86.7 0.0 1.2e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Sulfatase PF00884.18 KND88291.1 - 7.2e-19 68.1 0.2 1.3e-17 63.9 0.1 2.3 1 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KND88291.1 - 3.6e-05 23.2 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KND88291.1 - 0.0037 15.7 0.0 0.0051 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) p450 PF00067.17 KND88292.1 - 3e-66 223.8 0.0 3.5e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LigT_PEase PF02834.11 KND88292.1 - 0.093 12.7 0.5 0.4 10.6 0.1 2.2 2 1 0 2 2 2 0 LigT like Phosphoesterase PhyH PF05721.8 KND88293.1 - 4.9e-21 75.7 0.0 6.3e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.19 KND88294.1 - 5.3e-117 391.1 27.4 6.3e-117 390.9 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND88294.1 - 3.4e-18 65.4 34.3 3.4e-18 65.4 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UbiA PF01040.13 KND88295.1 - 1e-08 34.7 1.9 1.2e-08 34.4 1.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2530 PF10745.4 KND88295.1 - 0.054 13.4 0.7 0.1 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF4027 PF13219.1 KND88295.1 - 0.1 12.0 0.4 0.22 10.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DAO PF01266.19 KND88296.1 - 1.4e-25 89.9 0.6 1.8e-25 89.5 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND88296.1 - 1.4e-05 24.9 0.7 4.4e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND88296.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KND88296.1 - 0.0012 17.9 0.4 0.0012 17.9 0.3 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KND88296.1 - 0.0021 17.9 0.2 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND88296.1 - 0.0048 15.9 0.1 0.0078 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KND88296.1 - 0.02 15.3 0.3 0.05 14.0 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EthD PF07110.6 KND88297.1 - 1.9e-16 60.7 0.8 2.6e-16 60.2 0.5 1.2 1 0 0 1 1 1 1 EthD domain Methyltransf_23 PF13489.1 KND88298.1 - 9.6e-13 48.1 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND88298.1 - 0.0058 17.0 0.0 0.019 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND88298.1 - 0.0085 15.6 0.0 0.08 12.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 KND88299.1 - 4.4e-64 216.7 0.0 5.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KND88300.1 - 8.9e-18 64.9 1.3 1.5e-17 64.2 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND88300.1 - 6.8e-09 35.6 0.0 1.2e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND88300.1 - 1e-05 25.2 0.4 4.9e-05 22.9 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KND88300.1 - 3.6e-05 23.1 0.0 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KND88300.1 - 4.7e-05 23.1 0.0 9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KND88300.1 - 0.03 13.9 0.2 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 KND88300.1 - 0.18 11.1 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_M24 PF00557.19 KND88301.1 - 6.9e-41 140.1 0.0 9.6e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PAG PF15347.1 KND88301.1 - 0.48 9.4 5.1 0.84 8.6 3.5 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Peptidase_M24 PF00557.19 KND88302.1 - 3e-41 141.2 0.0 3.7e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KND88302.1 - 0.00015 21.5 4.2 0.00039 20.2 2.9 1.7 1 0 0 1 1 1 1 MYND finger GMC_oxred_C PF05199.8 KND88307.1 - 0.007 16.6 0.0 0.0091 16.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FMN_dh PF01070.13 KND88308.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NmrA PF05368.8 KND88309.1 - 3.6e-56 190.0 0.5 4.7e-56 189.6 0.4 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND88309.1 - 6.2e-16 58.9 0.6 8.7e-16 58.4 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND88309.1 - 4.3e-05 22.3 0.1 6.5e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Nitro_FeMo-Co PF02579.12 KND88309.1 - 0.11 12.5 0.6 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Peptidase_M1 PF01433.15 KND88310.1 - 6e-138 460.1 0.0 1e-137 459.3 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 KND88310.1 - 1.4e-92 310.3 0.0 2.7e-92 309.4 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KND88310.1 - 3.5e-20 72.3 0.4 6.6e-20 71.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily YppG PF14179.1 KND88311.1 - 5.7 7.5 10.9 14 6.3 7.6 1.6 1 0 0 1 1 1 0 YppG-like protein Fasciclin PF02469.17 KND88312.1 - 1e-46 158.1 0.0 5.5e-26 91.0 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF2580 PF10824.3 KND88312.1 - 0.0061 16.8 1.8 0.15 12.4 0.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2580) SNF PF00209.13 KND88313.1 - 0.00014 20.5 0.5 0.00015 20.4 0.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family AA_permease_2 PF13520.1 KND88314.1 - 9e-65 218.8 53.8 1.1e-64 218.5 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND88314.1 - 6e-33 113.9 49.9 8.1e-33 113.4 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KND88315.1 - 6.2e-34 117.2 4.1 4.1e-33 114.5 2.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88315.1 - 1.5e-07 31.1 12.3 2.4e-07 30.5 8.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase PF00117.23 KND88316.1 - 8.3e-14 51.4 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KND88316.1 - 6.5e-05 22.4 0.1 0.0016 17.9 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 KND88316.1 - 8.1e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 KND88317.1 - 3.2e-33 114.9 21.0 3.2e-33 114.9 14.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KND88318.1 - 2.2e-11 42.9 0.4 2.4e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88318.1 - 2.5e-06 27.2 6.2 6.1e-06 26.0 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2127 PF09900.4 KND88318.1 - 0.16 11.9 0.1 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) DUF1793 PF08760.6 KND88319.1 - 1e-63 214.2 0.4 1e-63 214.2 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) MFS_1 PF07690.11 KND88320.1 - 3.3e-30 104.9 36.0 3.3e-30 104.9 25.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 KND88320.1 - 0.0015 17.7 2.0 0.0032 16.6 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) UNC-93 PF05978.11 KND88320.1 - 0.012 15.0 3.7 0.032 13.7 2.6 1.7 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Sec1 PF00995.18 KND88321.1 - 5.4e-148 494.1 0.0 6.4e-148 493.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.19 KND88322.1 - 8.1e-05 22.1 2.9 0.00015 21.3 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KND88322.1 - 1 9.4 3.4 1.8 8.7 2.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Reo_sigmaC PF04582.7 KND88324.1 - 0.0011 18.2 10.7 0.15 11.2 1.3 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KND88324.1 - 0.0011 16.8 25.7 0.0011 16.8 17.8 3.2 3 1 1 4 4 4 2 Myosin tail Shugoshin_N PF07558.6 KND88324.1 - 0.0031 17.1 1.7 0.0031 17.1 1.2 5.4 6 0 0 6 6 6 1 Shugoshin N-terminal coiled-coil region Filament PF00038.16 KND88324.1 - 0.0033 16.9 19.0 0.0033 16.9 13.2 4.5 3 1 3 6 6 6 3 Intermediate filament protein TPR_MLP1_2 PF07926.7 KND88324.1 - 0.13 12.0 56.8 0.21 11.3 16.1 4.9 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KND88324.1 - 0.13 12.0 0.1 0.13 12.0 0.1 6.7 6 1 1 7 7 7 0 Homeobox associated leucine zipper DUF2450 PF10475.4 KND88324.1 - 2.3 7.0 17.2 0.096 11.5 5.0 2.9 2 1 1 3 3 3 0 Protein of unknown function N-terminal domain (DUF2450) ATG16 PF08614.6 KND88324.1 - 2.7 7.7 62.2 0.073 12.8 7.8 5.5 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KND88324.1 - 3.4 7.7 21.5 0.2 11.7 2.7 3.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Iso_dh PF00180.15 KND88325.1 - 1.3e-71 241.3 0.0 1.6e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.1 KND88326.1 - 5.9e-45 154.1 3.2 1.3e-34 120.2 0.4 2.0 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Geminin PF07412.7 KND88326.1 - 0.037 13.7 0.2 0.056 13.1 0.2 1.2 1 0 0 1 1 1 0 Geminin TMF_DNA_bd PF12329.3 KND88326.1 - 0.05 13.4 0.9 0.05 13.4 0.7 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tom5 PF10642.4 KND88326.1 - 0.26 10.9 0.9 0.43 10.2 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase AATase PF07247.7 KND88328.1 - 2.4e-16 59.3 0.0 8.8e-16 57.5 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KND88328.1 - 1.4e-08 33.9 1.2 2.1e-07 30.0 0.2 2.1 2 0 0 2 2 2 2 Condensation domain Plug_translocon PF10559.4 KND88329.1 - 0.17 11.4 0.1 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Plug domain of Sec61p AA_permease PF00324.16 KND88330.1 - 1.3e-54 185.3 24.0 1.6e-54 185.0 16.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND88330.1 - 2.4e-16 59.3 21.1 2.8e-16 59.0 14.6 1.0 1 0 0 1 1 1 1 Amino acid permease ABC2_membrane_5 PF13346.1 KND88330.1 - 5.4 6.2 16.2 8.5 5.6 10.2 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein ATG2_CAD PF13329.1 KND88331.1 - 1.4e-47 161.1 0.4 2.8e-47 160.2 0.3 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KND88331.1 - 4.6e-27 94.0 0.9 3.2e-26 91.3 0.0 3.0 4 0 0 4 4 4 1 ATG C terminal domain Amino_oxidase PF01593.19 KND88332.1 - 2.6e-48 165.2 0.1 1.1e-47 163.1 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND88332.1 - 3.6e-15 55.7 0.1 7.7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND88332.1 - 7.9e-07 28.2 0.2 2.7e-05 23.2 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND88332.1 - 6.3e-06 26.0 0.6 0.0054 16.5 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KND88332.1 - 3.2e-05 24.2 0.6 6.9e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND88332.1 - 8.2e-05 22.7 0.3 0.00018 21.6 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND88332.1 - 0.0018 17.1 1.2 0.012 14.4 0.3 2.2 2 1 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KND88332.1 - 0.0024 17.5 0.8 0.0037 16.9 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KND88332.1 - 0.0036 16.4 0.9 0.0056 15.7 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND88332.1 - 0.0047 15.4 0.1 0.04 12.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KND88332.1 - 0.0051 15.9 0.1 0.0082 15.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KND88332.1 - 0.016 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND88332.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rossmann-like PF10727.4 KND88332.1 - 0.17 11.6 0.0 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Rossmann-like domain Glyco_transf_8 PF01501.15 KND88334.1 - 1.3e-19 70.5 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 OPT PF03169.10 KND88336.1 - 1.2e-140 469.9 48.8 1.4e-140 469.7 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ClpS PF02617.12 KND88336.1 - 0.24 11.1 0.2 0.47 10.2 0.2 1.3 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Fungal_trans PF04082.13 KND88337.1 - 2.6e-05 23.2 0.3 0.00014 20.8 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain P4Ha_N PF08336.6 KND88337.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ADK PF00406.17 KND88339.1 - 3.4e-35 121.1 0.0 3.9e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KND88339.1 - 1.2e-13 50.4 0.0 2.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KND88339.1 - 7.2e-05 23.0 0.0 0.00046 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND88339.1 - 0.00023 21.9 0.0 0.00037 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND88339.1 - 0.0024 17.7 0.1 0.043 13.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KND88339.1 - 0.051 13.2 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KND88339.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ANTH PF07651.11 KND88340.1 - 2e-68 230.1 0.1 3e-68 229.5 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KND88340.1 - 1.9e-10 40.6 0.0 3.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Mito_carr PF00153.22 KND88342.1 - 9.2e-40 134.2 5.6 1e-15 57.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.17 KND88343.1 - 5.4e-57 193.0 0.5 7.3e-57 192.6 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KND88343.1 - 6.4e-28 96.3 1.7 9.8e-28 95.7 0.7 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain DUF2834 PF11196.3 KND88343.1 - 0.25 11.5 0.5 0.49 10.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) Plasmodium_Vir PF05795.6 KND88343.1 - 0.29 10.2 0.0 0.47 9.6 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BAR PF03114.13 KND88344.1 - 1.8e-06 27.6 0.1 3.4e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.5 KND88344.1 - 0.00031 20.0 0.7 0.00031 20.0 0.5 2.1 2 0 0 2 2 2 1 Vps5 C terminal like IncA PF04156.9 KND88344.1 - 0.66 9.5 9.5 0.098 12.2 1.7 2.2 2 0 0 2 2 2 0 IncA protein bZIP_2 PF07716.10 KND88344.1 - 5.8 6.8 9.9 4.3 7.2 0.9 3.2 3 0 0 3 3 3 0 Basic region leucine zipper 2OG-FeII_Oxy PF03171.15 KND88345.1 - 6.1e-23 80.9 0.0 1.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KND88345.1 - 2.1e-13 50.7 0.0 3.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HMG-CoA_red PF00368.13 KND88346.1 - 3.1e-154 513.1 2.5 4.4e-154 512.6 1.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KND88346.1 - 1.8e-46 157.5 0.2 3.4e-46 156.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KND88346.1 - 2.2e-14 53.1 7.7 5.4e-13 48.6 5.3 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KND88346.1 - 1.6e-09 36.3 4.1 2.5e-09 35.6 2.8 1.2 1 0 0 1 1 1 1 Patched family Isochorismatase PF00857.15 KND88347.1 - 4.4e-25 88.6 0.0 3.9e-24 85.5 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family FumaraseC_C PF10415.4 KND88348.1 - 3.5e-22 78.2 0.0 7.4e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus LETM1 PF07766.8 KND88349.1 - 1.4e-105 352.1 1.5 2.2e-105 351.5 1.0 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KND88349.1 - 0.00012 21.4 0.0 0.19 11.3 0.0 3.3 3 0 0 3 3 3 2 SAP domain SspK PF08176.7 KND88349.1 - 0.064 13.2 0.5 14 5.7 0.2 2.8 2 0 0 2 2 2 0 Small acid-soluble spore protein K family MFS_1 PF07690.11 KND88350.1 - 0.00054 18.7 0.4 0.00057 18.7 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND88350.1 - 0.00055 18.6 0.1 0.00059 18.5 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF456 PF04306.8 KND88350.1 - 0.0089 16.0 0.3 0.01 15.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Chitin_synth_1 PF01644.12 KND88351.1 - 3.1e-80 267.6 0.4 5.2e-80 266.9 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KND88351.1 - 5.2e-31 106.1 0.0 1.1e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KND88351.1 - 1.6e-23 82.8 0.3 1.4e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KND88351.1 - 2.3e-10 40.5 4.2 1.2e-09 38.1 2.9 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND88351.1 - 3.1e-07 30.4 0.0 3.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GbpC PF08363.5 KND88351.1 - 0.052 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucan-binding protein C FYVE PF01363.16 KND88352.1 - 0.0017 18.2 4.3 0.0017 18.2 3.0 2.9 3 0 0 3 3 3 1 FYVE zinc finger HCV_core PF01542.13 KND88354.1 - 0.33 11.3 4.6 0.099 13.0 1.1 1.6 2 0 0 2 2 2 0 Hepatitis C virus core protein Gly-zipper_OmpA PF13436.1 KND88354.1 - 6.3 6.4 7.4 12 5.6 5.1 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Glyco_transf_25 PF01755.12 KND88357.1 - 8e-10 38.6 0.0 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Mucin PF01456.12 KND88358.1 - 0.027 14.2 14.9 0.031 14.0 10.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3455 PF11937.3 KND88359.1 - 1.9e-25 89.8 0.0 3.2e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Hexapep PF00132.19 KND88360.1 - 3.8e-08 32.4 5.3 0.0011 18.3 1.3 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KND88360.1 - 3.6e-05 23.2 0.8 0.00056 19.4 0.3 2.8 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KND88360.1 - 0.035 12.6 0.1 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase UCH PF00443.24 KND88361.1 - 4.6e-48 163.6 0.0 1.7e-47 161.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND88361.1 - 1.3e-18 67.4 0.0 2.2e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.2 KND88361.1 - 1.6 8.7 8.5 0.42 10.6 0.6 2.9 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) UCR_14kD PF02271.11 KND88362.1 - 1.1e-40 137.6 0.9 1.4e-40 137.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Beta-lactamase PF00144.19 KND88362.1 - 0.027 13.4 0.1 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase Angiomotin_C PF12240.3 KND88362.1 - 0.038 13.5 0.3 0.052 13.0 0.2 1.1 1 0 0 1 1 1 0 Angiomotin C terminal Mito_carr PF00153.22 KND88364.1 - 1.7e-69 229.5 0.5 2.1e-23 81.8 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Dot_icm_IcmQ PF09475.5 KND88364.1 - 0.052 12.7 0.2 0.085 12.0 0.1 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) AhpC-TSA PF00578.16 KND88365.1 - 3e-26 91.5 0.0 5e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND88365.1 - 3.9e-15 55.6 0.0 5.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KND88365.1 - 0.00037 20.4 0.0 0.0032 17.3 0.0 2.3 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme CDC27 PF09507.5 KND88365.1 - 0.58 9.3 14.9 0.8 8.8 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.7 KND88365.1 - 8.6 6.1 8.0 13 5.6 5.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Yae1_N PF09811.4 KND88367.1 - 3.3e-09 36.1 4.8 4.7e-09 35.6 3.3 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.6 KND88368.1 - 1.5e-141 471.6 0.0 2.2e-141 471.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KND88368.1 - 7.5e-07 27.5 3.8 0.0014 16.7 0.0 3.7 3 2 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) FHIPEP PF00771.15 KND88368.1 - 0.21 9.8 0.5 0.27 9.5 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family Radial_spoke_3 PF06098.6 KND88368.1 - 0.34 9.8 6.1 0.58 9.1 4.3 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 BRF1 PF07741.8 KND88368.1 - 1.1 9.5 10.7 2.3 8.5 7.4 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Acetyltransf_1 PF00583.19 KND88369.1 - 2.7e-13 49.7 0.1 4.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KND88369.1 - 9.3e-06 25.3 0.1 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KND88369.1 - 0.0036 17.3 0.0 0.012 15.7 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND88369.1 - 0.01 15.9 0.1 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND88369.1 - 0.024 14.5 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.1 KND88370.1 - 4.5e-05 23.5 0.1 0.00015 21.7 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Spt20 PF12090.3 KND88370.1 - 0.11 11.8 4.3 0.19 11.0 3.0 1.3 1 0 0 1 1 1 0 Spt20 family AAA_23 PF13476.1 KND88370.1 - 0.47 10.7 7.3 1.1 9.5 0.8 2.3 2 0 0 2 2 2 0 AAA domain Suf PF05843.9 KND88370.1 - 0.7 9.5 12.3 0.017 14.8 2.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FCH PF00611.18 KND88371.1 - 2.9e-22 78.6 2.7 3.4e-22 78.4 0.0 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KND88371.1 - 2.2e-16 59.1 0.8 2.9e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 KND88371.1 - 3.1e-14 52.4 5.3 4.8e-14 51.8 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 KND88371.1 - 6.1e-12 44.7 0.0 7.8e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KND88371.1 - 0.0015 17.9 0.8 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 KND88371.1 - 0.0016 18.5 1.5 0.051 13.7 0.5 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Spc7 PF08317.6 KND88371.1 - 0.062 11.9 6.7 0.93 8.0 0.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Allexi_40kDa PF05549.6 KND88371.1 - 0.1 11.8 1.3 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein C1_2 PF03107.11 KND88371.1 - 0.55 10.3 7.8 0.98 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain Ax_dynein_light PF10211.4 KND88371.1 - 1.9 8.2 14.0 0.33 10.7 3.8 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain zf-C2H2 PF00096.21 KND88372.1 - 5.4e-05 23.2 15.1 0.15 12.4 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND88372.1 - 8.9e-05 22.5 14.1 0.24 11.8 1.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Cwf_Cwc_15 PF04889.7 KND88372.1 - 0.0063 16.2 5.3 0.01 15.5 3.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF812 PF05667.6 KND88372.1 - 0.03 12.8 4.2 0.041 12.4 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AIP3 PF03915.8 KND88372.1 - 0.033 13.1 2.7 0.046 12.6 1.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 FlxA PF14282.1 KND88372.1 - 0.035 14.0 4.5 0.064 13.2 3.1 1.3 1 0 0 1 1 1 0 FlxA-like protein Nic96 PF04097.9 KND88372.1 - 0.071 11.2 0.1 0.094 10.8 0.1 1.1 1 0 0 1 1 1 0 Nup93/Nic96 GET2 PF08690.5 KND88372.1 - 0.073 12.3 4.0 0.097 11.8 2.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Vfa1 PF08432.5 KND88372.1 - 0.084 12.8 6.1 0.14 12.2 4.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.14 KND88372.1 - 0.15 9.8 2.2 0.21 9.4 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-H2C2_2 PF13465.1 KND88372.1 - 0.23 11.8 16.9 2.7 8.4 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Sigma70_ner PF04546.8 KND88372.1 - 0.33 10.5 6.2 0.54 9.8 4.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DivIC PF04977.10 KND88372.1 - 0.35 10.3 2.7 0.66 9.4 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator AATF-Che1 PF13339.1 KND88372.1 - 0.77 9.9 7.5 2.9 8.0 1.2 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor APG6 PF04111.7 KND88372.1 - 1.2 8.0 6.4 1.8 7.5 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tho2 PF11262.3 KND88372.1 - 1.8 7.4 4.1 2.8 6.9 2.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Bap31 PF05529.7 KND88372.1 - 2 7.8 3.7 2.9 7.2 2.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2408 PF10303.4 KND88373.1 - 9.4e-47 158.4 6.1 1.2e-26 93.3 0.0 5.2 3 1 1 5 5 5 5 Protein of unknown function (DUF2408) DUF489 PF04356.7 KND88373.1 - 0.0063 16.1 1.5 0.062 12.8 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF489) HAP1_N PF04849.8 KND88373.1 - 0.012 14.5 2.7 0.018 14.0 1.9 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Abi_C PF14355.1 KND88373.1 - 0.013 15.4 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Abortive infection C-terminus DNA_photolyase PF00875.13 KND88373.1 - 0.065 12.9 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 DNA photolyase Snapin_Pallidin PF14712.1 KND88373.1 - 0.94 9.8 5.6 1.2 9.5 0.6 3.1 3 1 0 3 3 3 0 Snapin/Pallidin FUSC PF04632.7 KND88373.1 - 2.7 6.3 4.6 3.6 5.9 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ING PF12998.2 KND88373.1 - 4.1 7.7 6.7 1.5 9.1 0.5 2.8 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding YCII PF03795.9 KND88374.1 - 2.3e-06 27.7 0.0 3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UBX PF00789.15 KND88375.1 - 0.00068 19.6 1.1 0.0033 17.4 0.0 2.5 2 1 1 3 3 3 1 UBX domain UBA PF00627.26 KND88375.1 - 0.002 17.9 0.0 0.006 16.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain SOBP PF15279.1 KND88375.1 - 0.43 10.9 6.3 0.52 10.6 4.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TMPIT PF07851.8 KND88375.1 - 5.3 6.0 15.0 8.2 5.3 10.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_60s PF00428.14 KND88376.1 - 2.9e-19 69.2 14.2 1.6e-15 57.2 3.7 2.1 2 0 0 2 2 2 2 60s Acidic ribosomal protein FA_desaturase PF00487.19 KND88377.1 - 1.1e-30 106.9 20.7 1.1e-30 106.9 14.4 1.7 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.5 KND88377.1 - 6.1e-20 70.1 0.4 1.2e-19 69.2 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 KND88378.1 - 7.7e-23 80.2 0.0 5.2e-22 77.5 0.0 2.1 1 1 1 2 2 2 1 MSP (Major sperm protein) domain Tnp_DNA_bind PF14706.1 KND88378.1 - 0.014 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding ICE2 PF08426.5 KND88379.1 - 3.5e-138 460.6 10.8 4e-138 460.4 7.5 1.0 1 0 0 1 1 1 1 ICE2 DUF1440 PF07274.7 KND88379.1 - 8 6.4 7.2 3 7.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1440) Aa_trans PF01490.13 KND88380.1 - 5.8e-23 81.0 28.8 7.2e-23 80.7 20.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_2 PF12796.2 KND88381.1 - 3.4e-41 139.4 6.6 2.3e-12 47.0 0.4 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KND88381.1 - 6.2e-34 112.6 6.1 4.4e-05 23.3 0.1 9.9 8 2 2 10 10 10 7 Ankyrin repeat Ank PF00023.25 KND88381.1 - 1.9e-32 109.4 20.9 3.5e-06 26.5 0.2 9.2 9 1 1 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KND88381.1 - 2.6e-32 110.0 5.5 3.6e-08 33.4 0.3 6.9 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND88381.1 - 9e-29 99.3 3.8 1.2e-07 31.9 0.0 6.5 3 1 5 8 8 8 6 Ankyrin repeats (many copies) adh_short PF00106.20 KND88382.1 - 2.2e-12 47.1 0.0 3.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND88382.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND88382.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KND88382.1 - 0.0039 16.6 0.0 0.0073 15.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KND88382.1 - 0.0045 17.1 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1508 PF07411.7 KND88382.1 - 0.091 12.2 1.7 0.16 11.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) NAD_binding_10 PF13460.1 KND88382.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_18 PF00704.23 KND88383.1 - 5.1e-16 59.0 2.6 5.1e-16 59.0 1.8 2.3 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 CBM_1 PF00734.13 KND88383.1 - 2.5e-10 39.8 14.9 1.1e-09 37.8 10.3 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain COPIIcoated_ERV PF07970.7 KND88384.1 - 1.1e-33 116.7 0.0 1.6e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KND88384.1 - 5.4e-20 71.1 0.0 9.3e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_hydro_76 PF03663.9 KND88385.1 - 5.6e-136 453.7 12.6 7.7e-136 453.3 8.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KND88385.1 - 0.065 12.2 7.3 1.9 7.4 0.2 3.0 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 HET PF06985.6 KND88387.1 - 4.8e-20 72.1 0.0 9.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.21 KND88388.1 - 1.8e-10 40.4 0.0 3.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND88388.1 - 3.4e-08 33.2 0.1 2.4e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND88388.1 - 0.00068 20.5 0.0 0.0021 18.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AA_permease_2 PF13520.1 KND88389.1 - 5e-45 153.7 50.7 6.1e-45 153.5 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND88389.1 - 2.9e-24 85.2 44.1 4.9e-24 84.5 30.6 1.2 1 1 0 1 1 1 1 Amino acid permease Translin PF01997.11 KND88391.1 - 6.5e-45 153.2 0.0 7.5e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Translin family Gpi1 PF05024.10 KND88391.1 - 0.058 13.0 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) GMP_synt_C PF00958.17 KND88391.1 - 0.13 12.0 0.1 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 GMP synthase C terminal domain Pro-kuma_activ PF09286.6 KND88392.1 - 1.4e-24 86.7 0.0 3.8e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KND88392.1 - 2e-10 40.2 0.0 3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.11 KND88393.1 - 6.8e-22 77.6 25.9 6.8e-22 77.6 17.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KND88394.1 - 0.0002 20.1 0.3 0.00024 19.9 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MNSV_P7B PF06692.6 KND88394.1 - 0.0024 17.6 0.4 0.0047 16.6 0.3 1.4 1 0 0 1 1 1 1 Melon necrotic spot virus P7B protein Fungal_trans PF04082.13 KND88395.1 - 2.9e-20 72.2 0.0 6e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.16 KND88396.1 - 1.8e-44 151.7 0.1 2.5e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KND88396.1 - 1.6e-09 37.2 10.0 2.9e-05 23.6 0.3 2.4 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 KND88396.1 - 1.3e-05 24.6 4.6 6.7e-05 22.5 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND88396.1 - 0.00043 19.7 1.2 0.0011 18.5 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND88396.1 - 0.0015 18.4 1.6 0.0043 16.9 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat PMEI PF04043.10 KND88396.1 - 0.052 13.4 0.6 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor TPR_9 PF13371.1 KND88396.1 - 0.063 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND88396.1 - 0.19 12.4 0.8 0.57 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.14 KND88398.1 - 6e-41 140.2 0.0 1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KND88398.1 - 0.0028 17.4 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain DAO PF01266.19 KND88400.1 - 4.4e-43 147.5 0.0 5.2e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KND88400.1 - 1.3e-06 27.5 0.0 0.00026 19.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KND88400.1 - 1.4e-06 27.3 0.1 0.00073 18.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KND88400.1 - 2.1e-05 24.5 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND88400.1 - 3.4e-05 24.0 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND88400.1 - 0.00018 21.3 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KND88400.1 - 0.0013 18.6 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KND88400.1 - 0.0018 17.2 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 KND88400.1 - 0.025 13.0 0.0 3.2 6.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KND88400.1 - 0.052 13.9 0.0 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KND88400.1 - 0.095 12.6 0.0 0.26 11.3 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KND88400.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase MRP-L20 PF12824.2 KND88401.1 - 4.4e-50 169.8 1.3 5.1e-50 169.6 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KND88401.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Neugrin HypA PF01155.14 KND88402.1 - 0.074 12.7 2.3 0.12 12.0 1.6 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C3HC4 PF00097.20 KND88402.1 - 0.31 10.7 5.1 0.81 9.3 3.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Not3 PF04065.10 KND88403.1 - 1.2e-97 325.7 23.4 1.7e-97 325.2 16.2 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KND88403.1 - 5.6e-43 146.0 8.2 1.5e-42 144.6 5.7 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 KND88403.1 - 0.0052 16.7 6.2 0.037 13.9 0.3 2.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 KND88403.1 - 0.0058 16.1 3.6 0.013 15.0 2.5 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 KND88403.1 - 0.061 13.1 0.4 0.061 13.1 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Poty_PP PF08440.5 KND88403.1 - 0.07 12.1 1.3 0.14 11.1 0.9 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 KND88403.1 - 0.31 11.0 6.2 0.17 11.9 2.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Snapin_Pallidin PF14712.1 KND88403.1 - 0.42 10.9 8.5 2 8.7 0.2 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin PF00804.20 KND88403.1 - 1.5 9.0 15.6 0.08 13.1 3.8 2.6 1 1 1 2 2 2 0 Syntaxin ER_lumen_recept PF00810.13 KND88404.1 - 6.5e-35 120.7 8.5 1e-34 120.1 5.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KND88404.1 - 0.04 13.4 0.0 0.04 13.4 0.0 3.0 4 0 0 4 4 4 0 PQ loop repeat CS PF04969.11 KND88405.1 - 8e-15 55.1 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 CS domain LicD PF04991.8 KND88406.1 - 5.5e-29 101.7 3.1 3.4e-28 99.1 2.1 2.2 1 1 0 1 1 1 1 LicD family DUF2518 PF10726.4 KND88406.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of function (DUF2518) MAT1 PF06391.8 KND88407.1 - 1.7e-23 83.2 7.5 2.3e-23 82.8 5.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KND88407.1 - 3.4e-05 23.3 6.5 9.3e-05 22.0 4.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND88407.1 - 0.00039 20.3 7.7 0.001 19.0 5.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND88407.1 - 0.0042 16.7 9.0 0.01 15.4 6.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND88407.1 - 0.019 14.8 7.7 0.073 12.9 5.4 1.9 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 KND88407.1 - 0.026 14.2 11.2 0.2 11.3 7.9 2.1 1 1 1 2 2 2 0 zinc-RING finger domain MRP-S26 PF14943.1 KND88407.1 - 0.032 13.7 8.1 0.052 13.1 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-piccolo PF05715.8 KND88407.1 - 0.15 12.0 2.7 0.29 11.1 1.9 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_4 PF14570.1 KND88407.1 - 0.15 11.6 11.8 2.2 7.9 8.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KND88407.1 - 2.3 8.0 9.0 24 4.7 6.2 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger MR_MLE PF01188.16 KND88408.1 - 0.021 15.3 1.8 1.1 9.7 0.1 3.1 3 0 0 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain tRNA-synt_2 PF00152.15 KND88409.1 - 2.2e-76 256.7 0.0 1.4e-74 250.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) Pkinase PF00069.20 KND88410.1 - 2.8e-72 242.9 0.0 3.3e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88410.1 - 2.8e-31 108.5 0.0 4.1e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND88410.1 - 0.021 14.5 0.1 0.069 12.8 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KND88410.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.16 KND88411.1 - 1.3e-22 80.6 0.0 1.5e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Band_7 PF01145.20 KND88412.1 - 1.5e-24 86.8 6.4 2.2e-24 86.3 4.0 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KND88412.1 - 0.037 13.4 1.8 0.059 12.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) UcrQ PF02939.11 KND88413.1 - 1.2e-32 111.5 0.1 1.5e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 UcrQ family DUF676 PF05057.9 KND88414.1 - 7e-51 172.6 0.0 1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KND88414.1 - 2e-05 24.3 0.0 5.1e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND88414.1 - 0.00018 21.4 0.0 0.00049 20.0 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND88414.1 - 0.00091 18.8 0.0 0.002 17.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KND88414.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) RNase_T PF00929.19 KND88415.1 - 3.3e-07 30.7 0.0 3.7e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Exonuclease NIF PF03031.13 KND88416.1 - 1.2e-46 158.2 0.0 2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 KND88417.1 - 1.4e-50 171.9 0.2 4.5e-50 170.2 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 KND88417.1 - 0.0073 15.9 0.2 0.036 13.7 0.1 2.0 1 1 0 1 1 1 1 DeoR C terminal sensor domain Ribosomal_L7Ae PF01248.21 KND88418.1 - 1.1e-21 76.1 0.3 5e-21 74.0 0.2 2.1 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KND88418.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF1761 PF08570.5 KND88419.1 - 1.2e-23 83.5 1.8 1.4e-23 83.2 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) zf-CCHC PF00098.18 KND88420.1 - 8.6e-38 126.5 41.0 4.6e-09 35.7 2.4 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 KND88420.1 - 1.1e-10 40.9 29.2 0.0015 18.1 0.4 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.1 KND88420.1 - 2.9e-07 30.0 32.8 0.022 14.4 1.4 5.2 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 KND88420.1 - 3.2e-07 29.9 30.2 0.096 12.4 1.2 5.1 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 KND88420.1 - 0.052 13.0 0.8 0.052 13.0 0.6 4.5 3 1 2 5 5 5 0 Zinc knuckle Acyl-CoA_dh_1 PF00441.19 KND88421.1 - 1.2e-28 100.0 0.2 2.4e-28 99.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KND88421.1 - 1.6e-19 69.4 0.0 4e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KND88421.1 - 1.9e-18 65.6 1.1 4.4e-18 64.5 0.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KND88421.1 - 1.9e-08 34.8 0.1 4.3e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KND88421.1 - 0.0054 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.17 KND88422.1 - 3.3e-44 151.1 0.0 5.4e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KND88424.1 - 2.2e-18 66.0 0.1 2.9e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88424.1 - 6.8e-08 32.2 9.0 1.4e-07 31.2 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_ab_C PF00306.22 KND88424.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain FGGY_C PF02782.11 KND88425.1 - 5.5e-71 238.2 0.9 8.8e-71 237.6 0.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KND88425.1 - 8.2e-67 225.0 0.0 1.1e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 KND88426.1 - 2.8e-47 161.0 1.2 3.8e-47 160.6 0.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein APT PF03440.9 KND88426.1 - 0.039 13.6 0.3 0.28 10.8 0.3 2.1 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain DAO PF01266.19 KND88427.1 - 1.8e-47 161.9 3.0 2.9e-47 161.2 2.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND88427.1 - 3.9e-08 32.5 3.8 0.00073 18.4 0.8 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KND88427.1 - 6.6e-07 28.7 1.2 6e-06 25.5 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND88427.1 - 0.001 18.9 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND88427.1 - 0.004 17.1 0.6 0.014 15.3 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KND88427.1 - 0.0062 16.2 0.7 0.012 15.2 0.5 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KND88427.1 - 0.012 14.5 1.1 0.05 12.5 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KND88427.1 - 0.02 13.9 0.4 0.066 12.2 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KND88427.1 - 0.022 15.1 0.2 0.074 13.4 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND88427.1 - 0.023 13.8 0.1 0.052 12.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KND88427.1 - 0.036 12.5 0.4 0.055 11.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KND88427.1 - 0.061 12.1 0.2 0.18 10.6 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A tRNA-synt_1b PF00579.20 KND88428.1 - 9.8e-35 120.0 0.0 1.9e-22 79.7 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) SAE2 PF08573.5 KND88429.1 - 6.6e-26 90.8 0.8 2e-25 89.2 0.1 2.3 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Pkinase PF00069.20 KND88430.1 - 1.4e-70 237.4 0.0 2e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88430.1 - 2e-51 174.5 0.0 2.6e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND88430.1 - 0.00096 18.1 0.0 0.0053 15.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND88430.1 - 0.051 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LAT PF15234.1 KND88430.1 - 0.058 12.8 0.4 0.14 11.6 0.3 1.6 1 0 0 1 1 1 0 Linker for activation of T-cells Nipped-B_C PF12830.2 KND88431.1 - 0.038 13.6 1.1 6.8 6.2 0.1 3.3 4 1 0 4 4 4 0 Sister chromatid cohesion C-terminus Mur_ligase_M PF08245.7 KND88432.1 - 4.7e-06 26.7 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Mur ligase middle domain DUF2580 PF10824.3 KND88432.1 - 0.024 14.9 0.6 0.076 13.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) Mur_ligase_C PF02875.16 KND88432.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Ank PF00023.25 KND88435.1 - 5.2e-14 51.2 1.2 6.3e-07 28.9 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KND88435.1 - 2.2e-11 43.9 0.7 0.00032 20.9 0.4 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND88435.1 - 9.5e-11 41.5 1.8 3.4e-06 27.1 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND88435.1 - 6.9e-10 39.1 1.6 0.00079 19.8 0.4 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88435.1 - 6.2e-08 32.1 0.1 0.11 12.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KND88435.1 - 6.1e-07 29.0 0.1 4.7e-06 26.2 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Wzz PF02706.10 KND88436.1 - 0.98 9.2 7.4 1.8 8.3 5.1 1.4 1 0 0 1 1 1 0 Chain length determinant protein Ndr PF03096.9 KND88437.1 - 0.0012 17.4 0.0 0.0018 16.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family FlgN PF05130.7 KND88437.1 - 0.0077 16.4 0.9 0.015 15.5 0.6 1.4 1 0 0 1 1 1 1 FlgN protein zf-CCCH PF00642.19 KND88437.1 - 0.0078 15.8 3.7 0.038 13.6 2.6 2.3 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IncA PF04156.9 KND88437.1 - 0.37 10.3 2.6 0.58 9.7 1.8 1.2 1 0 0 1 1 1 0 IncA protein Pinin_SDK_memA PF04696.8 KND88437.1 - 0.46 10.0 2.7 0.89 9.1 1.9 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Actin PF00022.14 KND88438.1 - 1e-129 432.4 0.0 1.2e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Actin Clr5 PF14420.1 KND88439.1 - 1.4e-06 28.0 1.0 3.1e-06 26.9 0.3 2.0 2 0 0 2 2 2 1 Clr5 domain DUF892 PF05974.7 KND88439.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF3435 PF11917.3 KND88440.1 - 1.5e-05 23.9 0.0 2.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) APH PF01636.18 KND88441.1 - 1.2e-11 44.8 0.0 6.9e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88441.1 - 0.025 14.1 0.0 0.56 9.7 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase PNP_UDP_1 PF01048.15 KND88442.1 - 1.6e-06 27.3 0.6 2.3e-06 26.7 0.4 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 KND88443.1 - 7.6e-48 160.7 1.6 2.9e-14 53.1 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KND88443.1 - 3.5e-31 105.4 1.3 5.3e-07 29.1 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 KND88443.1 - 1.7e-26 89.5 0.1 0.0001 22.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KND88443.1 - 9.7e-26 89.6 1.2 5e-12 45.9 0.0 6.1 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND88443.1 - 4.8e-22 77.4 0.5 2.2e-07 30.8 0.0 4.7 3 1 3 6 6 6 4 Ankyrin repeats (many copies) NACHT PF05729.7 KND88443.1 - 0.00046 19.8 0.0 0.0018 17.9 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 KND88443.1 - 0.034 13.5 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND88443.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KND88443.1 - 0.074 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain EF-hand_1 PF00036.27 KND88445.1 - 2.1e-41 136.0 11.0 1.2e-09 36.8 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KND88445.1 - 2.1e-36 123.8 5.8 7.1e-20 70.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KND88445.1 - 6.2e-34 115.3 12.7 7.4e-16 57.5 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KND88445.1 - 6.3e-31 103.4 6.2 1.3e-09 37.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KND88445.1 - 8.5e-26 88.1 9.9 1.5e-06 27.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KND88445.1 - 2.9e-15 55.9 0.2 4.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KND88445.1 - 3.9e-09 36.1 1.9 0.00061 19.4 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KND88445.1 - 2e-08 34.2 0.1 0.0057 16.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KND88445.1 - 7.4e-08 31.8 0.1 0.024 14.2 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KND88445.1 - 7.1e-07 29.1 2.4 5e-06 26.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 KND88445.1 - 0.00031 20.3 0.1 0.086 12.3 0.0 2.6 2 2 1 3 3 3 1 Caleosin related protein TerB PF05099.8 KND88445.1 - 0.00083 19.1 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Tenui_NCP PF04876.7 KND88445.1 - 0.0011 18.5 0.1 0.052 13.0 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KND88445.1 - 0.0028 17.6 0.5 1.4 8.9 0.0 2.6 3 0 0 3 3 2 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KND88445.1 - 0.0066 16.7 1.1 1.9 8.8 0.0 2.5 1 1 0 2 2 2 1 Toprim-like DUF3349 PF11829.3 KND88445.1 - 0.061 13.7 0.3 9.8 6.6 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KND88445.1 - 0.14 11.8 2.1 0.95 9.1 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KND88445.1 - 0.41 10.2 3.2 0.94 9.0 0.1 2.2 1 1 1 2 2 2 0 RloB-like protein Adaptin_N PF01602.15 KND88446.1 - 4.9e-130 434.3 1.0 2.5e-65 220.8 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KND88446.1 - 4.1e-22 78.6 0.1 1.2e-21 77.1 0.1 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KND88446.1 - 1.3e-05 25.3 0.9 0.18 12.0 0.0 3.8 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KND88446.1 - 0.0043 16.9 2.4 0.5 10.1 1.1 3.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KND88446.1 - 0.014 15.8 2.0 11 6.6 0.1 4.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 KND88446.1 - 0.015 15.3 1.7 13 6.2 0.0 4.6 4 1 1 5 5 5 0 HEAT repeat PPR_3 PF13812.1 KND88447.1 - 0.0051 16.9 0.1 7.7 7.0 0.0 4.5 4 0 0 4 4 4 1 Pentatricopeptide repeat domain TPR_14 PF13428.1 KND88447.1 - 0.045 14.3 2.6 57 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SH PF01445.12 KND88447.1 - 0.11 12.1 0.2 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Viral small hydrophobic protein SNARE PF05739.14 KND88448.1 - 5e-20 70.9 2.7 5e-20 70.9 1.9 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KND88448.1 - 1.1e-12 48.0 7.7 2.9e-12 46.6 0.9 2.4 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KND88448.1 - 0.018 14.5 9.1 0.037 13.5 0.5 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRR19-TM PF15176.1 KND88448.1 - 0.026 14.1 0.1 0.093 12.4 0.0 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Cauli_DNA-bind PF03310.8 KND88448.1 - 0.036 13.9 3.7 0.038 13.8 0.6 2.1 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein ATG16 PF08614.6 KND88448.1 - 0.23 11.2 12.7 0.27 11.0 3.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fe-S_assembly PF04384.8 KND88448.1 - 0.33 11.3 1.6 1.6 9.1 0.2 2.4 2 0 0 2 2 2 0 Iron-sulphur cluster assembly IncA PF04156.9 KND88448.1 - 5.9 6.4 14.3 4.8 6.7 0.2 3.3 3 0 0 3 3 3 0 IncA protein Clathrin_lg_ch PF01086.12 KND88449.1 - 3.1e-68 230.0 2.7 3.5e-68 229.8 1.9 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 KND88449.1 - 0.14 11.7 0.3 0.35 10.4 0.2 1.6 1 0 0 1 1 1 0 Integrase core domain ATP-synt_B PF00430.13 KND88449.1 - 1.8 8.3 9.3 3.1 7.6 6.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) COX7a PF02238.10 KND88450.1 - 0.0069 16.0 1.4 0.07 12.8 0.3 2.7 2 1 1 3 3 3 1 Cytochrome c oxidase subunit VIIa ABC_membrane PF00664.18 KND88451.1 - 8.6e-44 149.9 11.3 1.2e-43 149.5 7.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KND88451.1 - 8.8e-34 116.7 0.0 2.4e-33 115.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KND88451.1 - 4.5e-05 22.7 0.0 0.0014 17.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KND88451.1 - 4.5e-05 23.5 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 KND88451.1 - 0.00027 21.0 0.4 0.66 9.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KND88451.1 - 0.0022 18.1 0.2 0.015 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND88451.1 - 0.004 17.9 0.0 0.0088 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KND88451.1 - 0.0078 15.7 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KND88451.1 - 0.012 14.2 0.1 0.024 13.2 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 KND88451.1 - 0.021 14.2 0.2 0.11 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KND88451.1 - 0.022 14.6 1.2 0.18 11.7 0.8 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KND88451.1 - 0.023 14.8 0.1 0.36 11.0 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND88451.1 - 0.037 13.7 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KND88451.1 - 0.079 12.3 0.1 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 KND88451.1 - 0.12 11.7 0.7 0.5 9.7 0.4 1.9 2 0 0 2 2 2 0 AAA-like domain CTD_bind PF04818.8 KND88452.1 - 7.6e-20 70.9 0.6 1.6e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 KND88452.1 - 0.05 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF3277 PF11681.3 KND88452.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) APH PF01636.18 KND88454.1 - 0.00057 19.6 0.1 0.0016 18.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KND88454.1 - 0.0023 17.1 0.0 0.0027 16.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.17 KND88455.1 - 7.3e-42 143.4 0.0 9.4e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GTPase_Cys_C PF12631.2 KND88456.1 - 0.21 11.9 0.9 3.9 7.9 0.0 2.6 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE PS_Dcarbxylase PF02666.10 KND88457.1 - 1.4e-82 275.9 0.0 3.1e-81 271.5 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Nitroreductase PF00881.19 KND88458.1 - 1e-13 51.4 0.1 1.2e-13 51.2 0.1 1.0 1 0 0 1 1 1 1 Nitroreductase family FAD_binding_1 PF00667.15 KND88459.1 - 2.5e-41 141.5 0.0 3.6e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KND88459.1 - 7.3e-10 39.3 0.0 1.8e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HNH_2 PF13391.1 KND88460.1 - 5.1e-11 42.1 0.4 1.7e-10 40.4 0.2 2.0 1 0 0 1 1 1 1 HNH endonuclease AAA PF00004.24 KND88461.1 - 9.2e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND88461.1 - 4.5e-06 26.4 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND88461.1 - 5.1e-06 26.6 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND88461.1 - 8.3e-05 21.7 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KND88461.1 - 0.00014 20.6 0.0 0.00026 19.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KND88461.1 - 0.00019 22.2 0.1 0.0006 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND88461.1 - 0.00019 21.0 0.9 0.001 18.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KND88461.1 - 0.00027 20.8 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND88461.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KND88461.1 - 0.0018 18.2 0.3 0.045 13.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KND88461.1 - 0.014 14.5 0.0 0.033 13.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KND88461.1 - 0.016 15.5 0.1 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND88461.1 - 0.022 14.4 0.2 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 KND88461.1 - 0.049 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 KND88461.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 KND88461.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KND88461.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein BRO1 PF03097.13 KND88462.1 - 2.7e-126 421.3 1.2 2.7e-126 421.3 0.9 2.3 2 0 0 2 2 2 1 BRO1-like domain FMN_dh PF01070.13 KND88462.1 - 1.2e-115 386.1 1.9 1.2e-115 386.1 1.3 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ALIX_LYPXL_bnd PF13949.1 KND88462.1 - 8.9e-93 310.4 16.2 8.9e-93 310.4 11.2 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Cyt-b5 PF00173.23 KND88462.1 - 4e-14 52.1 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KND88462.1 - 0.0024 16.8 0.0 0.0062 15.5 0.0 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KND88462.1 - 0.0054 15.6 0.2 0.013 14.4 0.2 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KND88462.1 - 0.035 13.2 0.4 0.089 11.9 0.2 1.6 1 0 0 1 1 1 0 Nitronate monooxygenase GLTP PF08718.6 KND88463.1 - 9.5e-44 149.0 0.0 1.6e-43 148.2 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Methyltransf_2 PF00891.13 KND88464.1 - 4.5e-28 98.0 0.4 1e-27 96.9 0.3 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KND88464.1 - 9.9e-05 22.1 0.0 0.00072 19.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_19 PF04672.7 KND88464.1 - 0.054 12.7 0.1 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase PLDc PF00614.17 KND88465.1 - 4.3e-14 51.7 1.3 1.1e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KND88465.1 - 4.1e-11 42.7 0.2 3.6e-05 23.5 0.0 3.9 4 0 0 4 4 4 3 PLD-like domain VPS11_C PF12451.3 KND88468.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal Methyltransf_23 PF13489.1 KND88469.1 - 4.3e-20 72.0 0.0 1.1e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND88469.1 - 2.3e-10 40.2 0.0 1.8e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND88469.1 - 6e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND88469.1 - 1.2e-07 32.2 0.0 2.2e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND88469.1 - 7.3e-07 29.5 0.0 4.8e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND88469.1 - 0.00013 21.1 0.0 0.00029 20.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KND88469.1 - 0.00022 20.3 0.0 0.003 16.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KND88469.1 - 0.00036 20.8 0.0 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND88469.1 - 0.00052 19.4 0.0 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KND88469.1 - 0.00099 19.1 0.0 0.0044 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND88469.1 - 0.013 14.6 0.0 0.17 10.9 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KND88469.1 - 0.023 14.1 0.0 0.052 13.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.13 KND88469.1 - 0.062 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase FtsJ PF01728.14 KND88469.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 KND88469.1 - 0.2 10.7 0.1 0.36 9.9 0.1 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Pkinase PF00069.20 KND88470.1 - 3.1e-30 105.1 0.0 4.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88470.1 - 6.6e-09 35.2 0.0 3.4e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND88470.1 - 0.26 10.0 0.1 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Septin PF00735.13 KND88471.1 - 1.9e-121 404.3 0.2 1.9e-121 404.3 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KND88471.1 - 4.1e-07 29.9 0.0 9.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND88471.1 - 3e-05 23.5 0.8 0.00074 18.9 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KND88471.1 - 4.6e-05 23.7 1.1 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KND88471.1 - 9.4e-05 21.6 0.5 0.00063 18.9 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KND88471.1 - 0.00035 20.1 0.6 0.002 17.5 0.1 2.1 2 1 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 KND88471.1 - 0.0015 17.6 2.0 0.0023 17.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KND88471.1 - 0.0027 17.7 0.0 0.014 15.3 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 KND88471.1 - 0.0028 18.1 0.0 0.012 16.0 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KND88471.1 - 0.0057 16.1 0.0 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 KND88471.1 - 0.0062 16.3 4.1 0.6 9.9 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_22 PF13401.1 KND88471.1 - 0.0071 16.4 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 KND88471.1 - 0.0079 15.5 1.0 0.038 13.3 0.0 2.4 3 0 0 3 3 2 1 Ras family AAA_29 PF13555.1 KND88471.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 KND88471.1 - 0.028 13.6 4.8 0.05 12.8 3.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.12 KND88471.1 - 0.051 13.1 0.1 8.1 5.9 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KND88471.1 - 0.083 12.2 0.1 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KND88471.1 - 0.092 12.4 1.8 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KND88471.1 - 0.11 12.7 0.5 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KND88471.1 - 0.11 12.0 0.8 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 KND88471.1 - 0.21 11.4 2.9 0.25 11.1 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 KND88471.1 - 0.32 9.6 11.5 0.5 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KND88471.1 - 0.71 9.6 4.7 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Phage_GPO PF05929.6 KND88471.1 - 0.85 8.8 5.9 1.4 8.1 4.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 KND88471.1 - 3.5 7.1 9.2 5.5 6.5 6.4 1.3 1 0 0 1 1 1 0 IncA protein Ferrochelatase PF00762.14 KND88472.1 - 1.3e-90 303.6 0.0 1.5e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.13 KND88472.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Ku PF02735.11 KND88473.1 - 3.7e-42 143.9 0.0 7.3e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KND88473.1 - 1.4e-35 122.7 0.0 2.1e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KND88473.1 - 3.4e-13 49.9 0.1 3.4e-13 49.9 0.1 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Zn_clus PF00172.13 KND88473.1 - 2.6e-07 30.4 11.4 2.9e-07 30.2 6.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toprim_3 PF13362.1 KND88473.1 - 0.041 14.1 0.0 2.6 8.3 0.0 3.0 3 0 0 3 3 3 0 Toprim domain MFS_1 PF07690.11 KND88474.1 - 1.8e-31 109.1 37.3 1.8e-31 109.1 25.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HlyE PF06109.8 KND88475.1 - 0.22 10.5 0.7 1.9 7.4 0.0 2.3 2 1 1 3 3 3 0 Haemolysin E (HlyE) Spc24 PF08286.6 KND88477.1 - 1.3e-39 134.5 0.0 6.6e-38 129.0 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 FUSC PF04632.7 KND88477.1 - 0.06 11.7 7.7 0.063 11.7 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PKI PF02827.11 KND88477.1 - 0.11 12.5 0.9 0.64 10.1 0.2 2.2 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF4164 PF13747.1 KND88477.1 - 0.31 11.1 9.0 0.41 10.8 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Viral_P18 PF04521.8 KND88477.1 - 0.55 9.6 3.5 0.63 9.4 0.7 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2580 PF10824.3 KND88477.1 - 0.59 10.5 8.7 0.98 9.8 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) DUF2937 PF11157.3 KND88477.1 - 0.8 9.0 6.2 0.34 10.2 1.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2937) Fis1_TPR_C PF14853.1 KND88478.1 - 1.7e-24 85.4 1.6 2.7e-24 84.7 1.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KND88478.1 - 4.2e-08 32.3 0.1 8.3e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KND88478.1 - 0.0062 16.3 1.0 0.01 15.6 0.7 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND88478.1 - 0.012 16.2 0.3 0.021 15.4 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2414 PF10309.4 KND88479.1 - 1.1e-17 63.4 0.0 2.3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KND88479.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain SRP72 PF08492.7 KND88480.1 - 1.2e-12 47.9 7.5 1.2e-12 47.9 5.2 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 KND88480.1 - 2.6e-06 27.4 7.2 0.0066 16.5 0.6 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KND88480.1 - 4.2e-06 27.2 40.0 0.042 14.5 2.1 7.3 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND88480.1 - 7.1e-05 22.4 23.0 0.15 12.0 0.0 7.4 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KND88480.1 - 0.00018 21.7 31.0 0.15 12.4 0.0 7.9 5 4 2 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND88480.1 - 0.0062 16.4 22.0 0.0083 16.0 1.7 6.5 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND88480.1 - 0.014 15.0 0.5 0.014 15.0 0.3 5.6 6 0 0 6 6 6 0 TPR repeat TPR_14 PF13428.1 KND88480.1 - 0.036 14.6 35.9 1.5 9.6 0.0 8.7 7 2 3 10 10 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND88480.1 - 0.053 13.1 12.6 6.3 6.5 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND88480.1 - 0.67 10.5 16.4 3.3 8.3 0.5 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND88480.1 - 0.78 10.3 18.2 5.9 7.6 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND88480.1 - 1.5 8.8 17.4 13 5.8 0.3 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND88480.1 - 2.5 8.0 8.4 5.3 7.0 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND88480.1 - 2.9 7.9 7.9 4 7.4 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat APH PF01636.18 KND88481.1 - 1.6e-14 54.2 0.0 3.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88481.1 - 0.0039 16.7 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Trypan_PARP PF05887.6 KND88481.1 - 0.032 14.0 2.6 0.052 13.3 1.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-BED PF02892.10 KND88482.1 - 0.00098 18.8 0.4 0.0025 17.5 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger zf-H2C2_5 PF13909.1 KND88482.1 - 0.59 10.4 3.1 2.2 8.7 2.1 2.0 1 1 0 1 1 1 0 C2H2-type zinc-finger domain Fungal_trans PF04082.13 KND88483.1 - 3.6e-26 91.6 0.4 5.2e-26 91.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridox_oxase_2 PF12766.2 KND88484.1 - 1.4e-20 73.4 0.0 2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YtxH PF12732.2 KND88486.1 - 2.2 8.6 5.1 4 7.8 3.5 1.4 1 0 0 1 1 1 0 YtxH-like protein LRR_9 PF14580.1 KND88487.1 - 5.1e-48 162.9 0.0 7.2e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KND88487.1 - 7e-09 35.1 0.1 0.00011 21.6 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND88487.1 - 3.9e-08 32.9 0.1 3.3e-07 29.9 0.0 2.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KND88487.1 - 0.00076 19.1 0.4 30 5.1 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KND88487.1 - 0.0025 17.7 1.5 12 6.6 0.0 4.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 KND88487.1 - 0.02 14.9 0.5 11 6.4 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat DUF4349 PF14257.1 KND88487.1 - 0.032 13.4 2.4 0.051 12.7 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CBFD_NFYB_HMF PF00808.18 KND88488.1 - 1.3e-11 44.3 1.6 2.1e-11 43.7 1.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND88488.1 - 0.00061 19.8 0.4 0.00089 19.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 KND88488.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2413 PF10310.4 KND88488.1 - 0.094 11.5 0.6 0.11 11.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1589 PF07628.6 KND88489.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) FANCI_S3 PF14677.1 KND88489.1 - 0.17 11.2 0.1 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 Pkinase PF00069.20 KND88490.1 - 1.6e-24 86.4 0.0 2.8e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KND88490.1 - 4.2e-11 42.2 19.3 1.1e-07 31.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 KND88490.1 - 9.9e-08 31.4 4.6 0.14 12.2 0.1 6.6 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KND88490.1 - 8.3e-05 22.7 0.6 0.04 14.1 0.0 3.7 1 1 3 4 4 4 1 HEAT repeats Pkinase_Tyr PF07714.12 KND88490.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND88490.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adaptin_N PF01602.15 KND88490.1 - 0.066 11.5 0.2 0.39 8.9 0.0 1.9 2 0 0 2 2 2 0 Adaptin N terminal region Kinase-like PF14531.1 KND88490.1 - 0.12 11.3 0.0 0.26 10.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like HEAT_EZ PF13513.1 KND88490.1 - 2.5 8.6 5.5 28 5.3 0.2 4.2 4 1 1 5 5 5 0 HEAT-like repeat Abhydrolase_6 PF12697.2 KND88491.1 - 1.3e-31 110.3 0.1 1.7e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND88491.1 - 1e-18 67.7 0.0 4.5e-18 65.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND88491.1 - 2.1e-15 56.7 0.0 3.3e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND88491.1 - 1.5e-06 27.9 0.0 3.2e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KND88491.1 - 0.00025 21.3 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KND88491.1 - 0.00033 20.1 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KND88491.1 - 0.00045 20.0 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 KND88491.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Acyl_transf_1 PF00698.16 KND88491.1 - 0.047 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain DLH PF01738.13 KND88491.1 - 0.06 12.6 0.0 0.87 8.8 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family LytR_C PF13399.1 KND88491.1 - 0.079 13.3 0.1 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Lipase_3 PF01764.20 KND88491.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 KND88491.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.11 KND88491.1 - 0.15 11.4 0.0 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ribosomal_S3Ae PF01015.13 KND88492.1 - 1.7e-82 275.5 4.0 2e-82 275.2 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Erythro-docking PF09277.6 KND88492.1 - 0.028 14.0 0.2 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking mRNA_cap_C PF03919.10 KND88492.1 - 0.035 14.4 0.0 0.088 13.1 0.0 1.8 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Syntaxin PF00804.20 KND88492.1 - 0.039 14.1 0.5 0.19 11.9 0.1 2.2 2 1 1 3 3 3 0 Syntaxin UPRTase PF14681.1 KND88493.1 - 4.3e-79 264.5 0.0 5.4e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KND88493.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KND88493.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 KND88494.1 - 3.2e-28 97.2 0.3 4.3e-28 96.8 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 KND88494.1 - 0.059 13.2 0.6 0.09 12.6 0.4 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG GTP_CH_N PF12471.3 KND88496.1 - 2.6e-67 226.2 0.0 1.2e-66 224.0 0.0 1.9 1 1 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KND88496.1 - 6.7e-15 54.7 0.1 3.2e-14 52.5 0.0 2.0 2 1 0 2 2 2 1 GTP cyclohydrolase II WD40 PF00400.27 KND88498.1 - 1.8e-35 119.5 7.1 5.1e-07 29.3 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KND88498.1 - 3.7e-08 33.3 0.1 0.00034 20.3 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1793 PF08760.6 KND88499.1 - 2e-54 184.0 0.0 4.1e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Acetyltransf_1 PF00583.19 KND88500.1 - 2e-17 63.0 0.0 2.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND88500.1 - 7.8e-08 32.3 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND88500.1 - 1.8e-07 31.2 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND88500.1 - 6.8e-07 28.9 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KND88500.1 - 5.4e-06 26.3 0.1 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND88500.1 - 0.0004 20.2 0.0 0.00076 19.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND88500.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_B_thumb PF14791.1 KND88501.1 - 6.1e-22 77.0 0.0 1.1e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KND88501.1 - 9.4e-22 76.3 2.3 1e-21 76.1 0.5 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 KND88501.1 - 3.3e-19 68.9 0.0 5.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KND88501.1 - 2.9e-09 36.9 0.0 6.6e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KND88501.1 - 0.0065 16.6 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KND88501.1 - 0.066 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF2838 PF10998.3 KND88503.1 - 3.3e-44 149.2 9.4 3.3e-44 149.2 6.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) CHD5 PF04420.9 KND88503.1 - 0.0018 17.9 0.1 0.0062 16.2 0.1 1.9 1 1 0 1 1 1 1 CHD5-like protein Apolipoprotein PF01442.13 KND88503.1 - 0.034 13.6 0.0 0.075 12.5 0.0 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 KND88503.1 - 0.087 12.4 0.5 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 IncA protein SMC_N PF02463.14 KND88504.1 - 5.7e-59 198.9 0.0 1.4e-58 197.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KND88504.1 - 1.9e-26 92.4 0.0 7.4e-26 90.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KND88504.1 - 1.4e-12 48.3 9.8 1.4e-12 48.3 6.8 6.2 3 2 2 5 5 5 1 AAA domain TFIIE_alpha PF02002.12 KND88504.1 - 4.7e-12 45.3 0.1 1.8e-11 43.5 0.1 2.0 1 0 0 1 1 1 1 TFIIE alpha subunit AAA_21 PF13304.1 KND88504.1 - 1e-10 42.0 1.2 0.00025 21.0 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND88504.1 - 2.5e-08 33.3 0.0 7.5e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KND88504.1 - 0.002 17.3 20.8 0.058 12.5 0.3 5.1 4 1 1 5 5 5 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 KND88504.1 - 0.0025 17.6 0.0 0.045 13.6 0.0 3.1 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit Peptidase_M14 PF00246.19 KND88505.1 - 4.7e-65 219.9 0.0 6.3e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 KND88506.1 - 7.8e-41 139.8 0.0 1.4e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KND88506.1 - 8.8e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KND88506.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 PH domain zf-C2H2 PF00096.21 KND88507.1 - 0.00017 21.7 18.9 1.5 9.3 0.3 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND88507.1 - 0.00019 21.5 15.2 0.14 12.5 0.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KND88507.1 - 0.002 17.9 1.0 0.074 12.9 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger DUF230 PF03003.11 KND88507.1 - 0.053 13.0 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Poxvirus proteins of unknown function DUF629 PF04780.7 KND88507.1 - 0.067 11.7 0.0 0.44 9.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Methyltransf_16 PF10294.4 KND88508.1 - 3.7e-08 32.9 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KND88508.1 - 0.0034 16.5 0.1 0.0048 16.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Gas_vesicle_C PF01304.12 KND88508.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Vps39_2 PF10367.4 KND88509.1 - 1.2e-05 25.4 0.0 3.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KND88509.1 - 0.0081 16.1 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 KND88510.1 - 9.5e-91 303.2 0.1 9.5e-91 303.2 0.1 3.4 2 1 1 3 3 3 1 CASP C terminal bZIP_2 PF07716.10 KND88510.1 - 0.0042 16.8 6.3 0.0042 16.8 4.4 8.2 9 1 0 9 9 9 2 Basic region leucine zipper CENP-F_leu_zip PF10473.4 KND88510.1 - 0.39 10.5 64.4 0.023 14.5 4.9 5.7 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KND88510.1 - 1.6 8.5 49.7 0.4 10.4 0.3 5.4 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 KND88510.1 - 2.7 7.5 44.8 0.068 12.6 1.2 6.6 7 1 0 7 7 7 0 Septum formation initiator DUF3584 PF12128.3 KND88510.1 - 8.7 3.5 47.7 1 6.6 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Hydrolase_4 PF12146.3 KND88511.1 - 1.1e-22 79.6 0.4 9.5e-21 73.4 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KND88511.1 - 9.5e-21 74.7 4.0 1.1e-20 74.4 2.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND88511.1 - 1.8e-18 66.6 0.4 2.5e-18 66.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND88511.1 - 0.00014 21.5 0.1 0.002 17.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND88511.1 - 0.0002 20.6 0.8 0.47 9.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KND88511.1 - 0.0014 17.5 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KND88511.1 - 0.0027 16.6 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KND88511.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KND88511.1 - 0.1 12.0 0.4 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 Putative esterase DLH PF01738.13 KND88511.1 - 0.19 10.9 0.8 4.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 KND88511.1 - 0.2 9.9 0.2 9.1 4.4 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Cation_efflux PF01545.16 KND88512.1 - 9.7e-29 100.3 4.4 1.2e-28 99.9 3.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF202 PF02656.10 KND88512.1 - 0.27 11.4 3.7 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Glyco_transf_8 PF01501.15 KND88513.1 - 7.6e-30 104.0 0.0 1.3e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KND88513.1 - 0.005 16.2 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative zf-rbx1 PF12678.2 KND88514.1 - 8.8e-12 44.9 1.4 1.6e-11 44.0 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KND88514.1 - 9.7e-11 41.3 4.5 1.8e-10 40.4 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND88514.1 - 2.7e-06 26.9 6.5 3.9e-05 23.2 5.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND88514.1 - 5.3e-06 26.0 1.5 1.1e-05 25.0 1.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KND88514.1 - 6.6e-05 22.6 0.6 0.00014 21.6 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KND88514.1 - 6.6e-05 22.4 3.5 0.00012 21.6 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND88514.1 - 0.0012 18.8 4.9 0.0048 16.9 3.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KND88514.1 - 0.03 13.8 0.3 0.064 12.7 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KND88514.1 - 0.08 12.6 3.9 0.18 11.5 2.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KND88514.1 - 0.84 9.6 3.1 3.6 7.6 2.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KND88514.1 - 1 8.9 2.8 0.88 9.2 0.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain F-box-like PF12937.2 KND88516.1 - 0.0069 16.0 0.0 0.021 14.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND88516.1 - 0.068 12.8 0.0 0.28 10.8 0.0 2.0 1 0 0 1 1 1 0 F-box domain UPF0147 PF03685.8 KND88518.1 - 0.0018 18.1 0.8 0.19 11.6 0.0 3.1 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0147) DUF2194 PF09960.4 KND88518.1 - 0.32 9.0 2.2 0.2 9.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF4071 PF13281.1 KND88518.1 - 1.4 7.7 11.4 0.093 11.5 3.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4071) Pkinase PF00069.20 KND88519.1 - 5.4e-11 42.1 0.0 3.6e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88519.1 - 2.3e-08 33.4 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND88519.1 - 0.00013 21.7 1.3 0.074 12.7 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88519.1 - 0.0012 18.4 0.0 0.14 11.6 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase Kinase-like PF14531.1 KND88519.1 - 0.017 14.0 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Xan_ur_permease PF00860.15 KND88521.1 - 8.3e-17 60.7 24.3 1e-09 37.4 6.2 2.8 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.15 KND88521.1 - 0.049 12.6 6.0 0.018 14.0 1.8 2.0 1 1 0 2 2 2 0 Sulfate transporter family Dicty_CAR PF05462.6 KND88522.1 - 9.5e-13 47.7 7.7 9.5e-13 47.7 5.4 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KND88522.1 - 5.3e-12 45.3 5.0 8.8e-12 44.6 3.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 KND88522.1 - 5.7e-08 32.2 2.4 7.4e-08 31.8 1.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KND88522.1 - 6e-05 22.3 4.3 9e-05 21.7 3.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KND88522.1 - 0.0062 16.1 14.5 0.018 14.6 10.1 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.12 KND88522.1 - 0.067 11.9 12.5 8.9 4.9 8.7 2.4 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Ank_2 PF12796.2 KND88523.1 - 2.7e-19 69.2 0.0 1.4e-11 44.5 0.0 2.4 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND88523.1 - 2.2e-09 36.6 0.1 0.0023 17.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KND88523.1 - 3.7e-08 33.6 0.1 2e-05 24.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88523.1 - 6.1e-07 29.0 0.0 0.15 12.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KND88523.1 - 4.1e-06 26.8 0.0 0.0062 16.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Peptidase_C12 PF01088.16 KND88524.1 - 6.9e-70 234.5 0.0 8.4e-70 234.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YodL PF14191.1 KND88524.1 - 0.082 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 YodL-like RCC1 PF00415.13 KND88525.1 - 3.7e-50 167.9 14.9 5.7e-09 36.0 0.0 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KND88525.1 - 1.2e-28 98.0 29.6 8e-07 28.5 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF2407 PF10302.4 KND88526.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KND88526.1 - 0.0003 20.1 0.0 0.00066 19.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Gastrin PF00918.12 KND88526.1 - 2.2 9.1 0.0 2.2 9.1 0.0 3.4 4 0 0 4 4 4 0 Gastrin/cholecystokinin family S4 PF01479.20 KND88527.1 - 9e-15 53.8 0.0 1.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KND88527.1 - 0.0056 16.2 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 S4 domain Fungal_trans PF04082.13 KND88528.1 - 7.1e-42 143.0 0.0 1.1e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88528.1 - 2.1e-08 33.9 5.9 4.6e-08 32.8 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dicty_REP PF05086.7 KND88528.1 - 0.072 10.8 2.9 0.097 10.4 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 KND88528.1 - 0.31 10.2 21.4 0.48 9.5 14.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4367 PF14285.1 KND88528.1 - 0.63 9.3 1.8 1.1 8.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Fungal_trans PF04082.13 KND88529.1 - 3.4e-28 98.2 0.0 6.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88529.1 - 1.2e-09 37.9 9.8 2.1e-09 37.1 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flu_B_NS1 PF02942.9 KND88530.1 - 0.14 11.0 0.8 0.22 10.3 0.6 1.2 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Mcm10 PF09332.6 KND88530.1 - 0.64 9.3 4.8 1.3 8.3 0.3 2.3 2 0 0 2 2 2 0 Mcm10 replication factor OmpH PF03938.9 KND88530.1 - 1.1 9.1 6.5 8.2 6.3 1.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2664 PF10867.3 KND88530.1 - 6.4 7.4 8.6 18 6.0 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Amidohydro_1 PF01979.15 KND88531.1 - 6.5e-39 134.5 0.0 9e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND88531.1 - 3.5e-06 26.7 0.0 9.1e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KND88531.1 - 7.9e-06 25.3 6.5 7.3e-05 22.1 0.4 3.1 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KND88531.1 - 0.00054 20.0 0.0 0.077 13.0 0.0 2.8 1 1 0 1 1 1 1 Amidohydrolase Acyl_transf_1 PF00698.16 KND88532.1 - 6.4e-78 262.2 0.0 6.9e-77 258.8 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KND88532.1 - 9.1e-38 128.4 0.0 1.9e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KND88532.1 - 2e-29 101.1 1.1 4.4e-29 100.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KND88532.1 - 3.8e-23 81.7 0.0 1.4e-22 79.8 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KND88532.1 - 0.00036 19.8 0.1 0.052 12.6 0.0 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase PCIF1_WW PF12237.3 KND88532.1 - 0.009 15.3 0.1 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain ketoacyl-synt PF00109.21 KND88533.1 - 1.3e-19 70.6 0.0 2.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KND88533.1 - 5.4e-19 68.1 0.0 1.3e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.1 KND88533.1 - 2e-16 60.4 0.0 7.9e-15 55.2 0.0 2.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KND88533.1 - 5.9e-12 45.4 0.1 3.1e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KND88533.1 - 2.1e-05 24.5 0.0 7.3e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND88533.1 - 0.00038 20.1 0.1 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 KR domain LSM PF01423.17 KND88534.1 - 5.6e-14 51.4 0.0 8.3e-14 50.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 KND88535.1 - 5.6e-10 38.7 0.0 3.2e-06 26.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND88535.1 - 9.3e-06 24.8 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KND88535.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KND88536.1 - 6.7e-07 28.7 0.0 9.9e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF4631 PF15450.1 KND88536.1 - 0.042 12.1 0.3 0.056 11.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) TFIIF_alpha PF05793.7 KND88536.1 - 0.22 9.8 6.0 0.27 9.5 4.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) APH PF01636.18 KND88537.1 - 4.7e-16 59.2 0.1 2.1e-15 57.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KND88538.1 - 5.5e-16 58.4 0.0 1.1e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND88538.1 - 2.4e-13 49.8 0.0 3.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND88538.1 - 0.037 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND88538.1 - 0.079 12.6 1.0 0.28 10.8 0.3 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KND88539.1 - 3.3e-49 167.3 0.0 4.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88539.1 - 7.4e-35 120.2 0.0 9.3e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND88539.1 - 6.2e-06 25.3 0.0 7e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND88539.1 - 0.00012 21.8 0.0 0.045 13.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KND88539.1 - 0.00064 18.8 0.0 0.00084 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PPR_3 PF13812.1 KND88547.1 - 3.5e-19 67.4 5.2 2.3e-06 27.4 0.0 7.2 6 1 1 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KND88547.1 - 1.3e-12 47.4 0.2 0.027 14.4 0.0 5.5 5 1 1 6 6 6 4 PPR repeat family PPR PF01535.15 KND88547.1 - 1.1e-09 37.6 2.2 0.01 15.7 0.0 4.9 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 KND88547.1 - 4.8e-06 25.9 0.1 0.027 13.9 0.0 4.1 4 0 0 4 4 4 2 PPR repeat LysM PF01476.15 KND88549.1 - 7e-12 45.0 0.8 0.0036 17.1 0.0 3.2 3 0 0 3 3 3 3 LysM domain HMGL-like PF00682.14 KND88550.1 - 1.1e-66 224.9 0.8 1.7e-66 224.2 0.5 1.3 1 0 0 1 1 1 1 HMGL-like PTR2 PF00854.16 KND88550.1 - 5.4e-41 140.6 8.9 1.2e-22 80.2 0.2 2.5 2 0 0 2 2 2 2 POT family AP_endonuc_2 PF01261.19 KND88550.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel 2OG-FeII_Oxy PF03171.15 KND88552.1 - 1.3e-21 76.7 0.0 2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KND88553.1 - 5.8e-118 394.3 0.0 1.2e-64 218.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF1108 PF06531.6 KND88553.1 - 0.32 11.1 0.1 0.72 10.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) Cyclase PF04199.8 KND88554.1 - 2.5e-17 63.1 0.0 3.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase FAD_binding_3 PF01494.14 KND88555.1 - 4e-09 35.9 1.1 0.00037 19.6 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KND88555.1 - 0.052 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SF3a60_bindingd PF12108.3 KND88556.1 - 0.14 11.6 0.2 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain tRNA-synt_1 PF00133.17 KND88557.1 - 1.5e-207 690.3 0.0 1.2e-206 687.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KND88557.1 - 3.1e-29 101.6 0.1 6.9e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KND88557.1 - 1.7e-14 53.2 0.2 0.0034 16.0 0.0 5.2 4 1 0 5 5 5 5 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KND88557.1 - 6.6e-11 41.8 0.1 1.4e-06 27.7 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KND88557.1 - 0.00065 19.7 1.1 0.00065 19.7 0.8 2.9 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm Sec39 PF08314.6 KND88558.1 - 1.1e-185 618.5 0.0 1.3e-185 618.3 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RRM_1 PF00076.17 KND88559.1 - 9.8e-21 73.1 0.0 1.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88559.1 - 2.4e-15 56.2 0.0 3.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88559.1 - 5.7e-12 45.3 0.0 8.1e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndufs5 PF10200.4 KND88560.1 - 0.00034 20.5 0.1 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KND88560.1 - 0.041 14.0 0.2 0.11 12.6 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) COX6B PF02297.12 KND88560.1 - 0.085 12.8 0.2 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Glyco_transf_41 PF13844.1 KND88564.1 - 2.1e-92 309.5 0.0 8.3e-47 159.2 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KND88564.1 - 1.4e-21 75.9 4.5 1.6e-06 27.6 0.1 5.6 3 2 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 KND88564.1 - 2.2e-21 74.4 0.3 0.0018 17.7 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KND88564.1 - 3.4e-18 64.0 1.1 0.091 12.7 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND88564.1 - 1.1e-14 54.1 3.0 3.4e-05 23.6 0.1 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 KND88564.1 - 7.1e-12 44.2 0.7 0.0031 17.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND88564.1 - 7.4e-10 39.2 2.4 0.014 16.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND88564.1 - 3.8e-09 36.0 0.1 0.0067 16.5 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND88564.1 - 7e-09 35.5 1.6 0.0069 16.9 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KND88564.1 - 3.5e-05 23.5 5.2 4.9 7.2 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KND88564.1 - 4e-05 23.0 0.6 0.93 9.4 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND88564.1 - 5.6e-05 23.4 0.4 0.5 10.7 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KND88564.1 - 0.00042 20.4 0.2 1.9 8.6 0.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KND88564.1 - 0.0046 16.7 1.3 0.11 12.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 KND88564.1 - 0.027 14.7 3.9 1.1 9.5 0.0 4.0 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 KND88564.1 - 0.05 14.0 0.5 39 5.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 KND88564.1 - 0.082 11.9 0.3 3.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 KND88565.1 - 3e-23 81.6 1.4 1.9e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND88565.1 - 7.9e-18 64.3 1.2 4.2e-12 45.9 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 KND88565.1 - 0.037 14.0 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) PAT1 PF09770.4 KND88565.1 - 0.051 11.8 27.7 0.057 11.6 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FYDLN_acid PF09538.5 KND88565.1 - 0.07 13.7 4.5 0.13 12.8 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zip PF02535.17 KND88565.1 - 0.5 9.3 1.6 0.55 9.1 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 KND88565.1 - 0.54 9.5 24.0 0.71 9.1 16.6 1.2 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 KND88565.1 - 0.95 9.1 13.9 1.5 8.5 9.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NARP1 PF12569.3 KND88565.1 - 2.8 6.6 16.6 3.4 6.3 11.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 KND88565.1 - 5.6 6.7 16.0 8.6 6.1 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec23_trunk PF04811.10 KND88566.1 - 1e-77 260.7 0.0 1.4e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KND88566.1 - 5.6e-34 115.6 0.6 3.5e-33 113.1 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KND88566.1 - 1.1e-29 102.7 0.2 2.5e-29 101.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KND88566.1 - 1.7e-16 59.4 6.4 3.2e-16 58.5 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KND88566.1 - 2.7e-13 49.4 0.0 6.1e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 KND88567.1 - 3.5e-18 64.8 0.2 6.6e-18 63.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KND88567.1 - 2.2e-11 43.6 0.2 3.7e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4386 PF14329.1 KND88568.1 - 0.049 13.1 8.9 0.065 12.7 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Hce2 PF14856.1 KND88569.1 - 4.3e-14 52.1 0.0 5.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor OrfB_Zn_ribbon PF07282.6 KND88570.1 - 9.4 5.9 6.8 28 4.4 4.6 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain LysM PF01476.15 KND88571.1 - 1.1e-09 38.0 0.0 4.1e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 LysM domain LysM PF01476.15 KND88572.1 - 1.1e-09 38.0 0.4 0.0043 16.9 0.1 4.3 4 0 0 4 4 4 3 LysM domain DUF2413 PF10310.4 KND88573.1 - 7.9 5.1 9.3 9.5 4.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SHR3_chaperone PF08229.6 KND88574.1 - 0.17 10.8 0.2 0.3 10.0 0.2 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 RPEL PF02755.10 KND88574.1 - 0.71 9.2 3.1 1.8 8.0 2.2 1.7 1 0 0 1 1 1 0 RPEL repeat APH PF01636.18 KND88575.1 - 0.00014 21.6 0.2 0.00019 21.2 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family IL13 PF03487.8 KND88575.1 - 0.034 13.8 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Interleukin-13 Abhydrolase_3 PF07859.8 KND88576.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KND88578.1 - 3.3e-43 147.7 0.0 4.7e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KND88578.1 - 1.8e-06 26.9 0.0 2.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family FIST_C PF10442.4 KND88578.1 - 0.087 12.7 0.0 1.3 8.9 0.0 2.7 2 1 1 3 3 3 0 FIST C domain Peptidase_S28 PF05577.7 KND88579.1 - 2.7e-44 151.4 0.1 3.1e-34 118.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 STN PF07660.9 KND88580.1 - 0.031 13.8 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Lyase_1 PF00206.15 KND88581.1 - 3.4e-17 62.5 0.0 4.8e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KND88581.1 - 3.9e-12 45.9 0.0 1.2e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus PPV_E1_C PF00519.12 KND88581.1 - 0.0027 16.4 0.0 0.0041 15.7 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase p450 PF00067.17 KND88582.1 - 2.9e-31 108.5 0.0 4.6e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PAN_4 PF14295.1 KND88584.1 - 0.00052 19.6 1.6 0.0012 18.5 1.1 1.6 1 0 0 1 1 1 1 PAN domain RskA PF10099.4 KND88584.1 - 0.0068 16.1 0.9 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Anti-sigma-K factor rskA SecE PF00584.15 KND88585.1 - 6.3e-11 41.6 0.0 8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Asparaginase_2 PF01112.13 KND88586.1 - 2.2e-83 279.6 0.5 3.2e-83 279.0 0.4 1.1 1 0 0 1 1 1 1 Asparaginase 2-Hacid_dh_C PF02826.14 KND88586.1 - 6.1e-35 119.9 0.0 1.5e-25 89.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PTPA PF03095.10 KND88588.1 - 5.7e-106 354.0 0.0 6.7e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PV-1 PF06637.6 KND88589.1 - 0.088 11.3 5.9 0.18 10.3 4.1 1.5 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1664 PF07889.7 KND88589.1 - 0.19 11.5 0.8 9 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 KND88590.1 - 6.4e-07 29.2 3.7 1.1e-06 28.4 2.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF479 PF04336.7 KND88590.1 - 0.17 12.0 0.3 0.42 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF479 bZIP_2 PF07716.10 KND88590.1 - 0.5 10.2 5.9 1.2 9.0 4.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Complex1_LYR_1 PF13232.1 KND88591.1 - 0.00015 21.9 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KND88591.1 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Velvet PF11754.3 KND88593.1 - 3.5e-47 160.6 0.3 8e-47 159.4 0.2 1.5 1 1 0 1 1 1 1 Velvet factor Acetyltransf_1 PF00583.19 KND88594.1 - 2e-09 37.3 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND88594.1 - 1.6e-07 31.3 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND88594.1 - 4.6e-06 26.7 0.0 2.2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND88594.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Filament PF00038.16 KND88595.1 - 4e-05 23.2 124.6 0.0093 15.4 24.6 5.5 1 1 4 5 5 5 4 Intermediate filament protein DUF4201 PF13870.1 KND88595.1 - 0.0062 15.9 0.4 0.0062 15.9 0.3 7.9 1 1 4 7 7 7 3 Domain of unknown function (DUF4201) Med9 PF07544.8 KND88595.1 - 0.024 14.3 0.7 0.024 14.3 0.5 8.6 8 2 1 9 9 9 0 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 KND88595.1 - 0.15 11.1 73.7 0.023 13.9 4.6 7.6 1 1 7 9 9 9 0 Reovirus sigma C capsid protein Matrilin_ccoil PF10393.4 KND88595.1 - 0.99 8.8 18.8 0.21 11.0 0.3 5.8 6 1 0 6 6 6 0 Trimeric coiled-coil oligomerisation domain of matrilin TRAP-gamma PF07074.7 KND88596.1 - 0.051 13.1 0.3 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) 7TMR-DISM_7TM PF07695.6 KND88596.1 - 3.7 7.1 12.7 0.69 9.5 0.7 3.0 2 1 1 3 3 3 0 7TM diverse intracellular signalling Ubie_methyltran PF01209.13 KND88597.1 - 3.6e-77 258.6 0.0 4.4e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KND88597.1 - 5e-15 55.4 0.0 6.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND88597.1 - 9.1e-13 48.5 0.0 4.9e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND88597.1 - 2.2e-10 40.8 0.0 3.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND88597.1 - 1.3e-09 38.2 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND88597.1 - 3.1e-09 36.7 0.0 4.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND88597.1 - 1.2e-07 32.2 0.0 2.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND88597.1 - 3.2e-06 27.1 0.0 8.9e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND88597.1 - 0.091 12.1 0.0 0.61 9.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 KND88597.1 - 0.094 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF2433 PF10360.4 KND88598.1 - 4.1e-54 182.4 0.0 6.5e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 KND88598.1 - 0.0019 18.4 5.4 0.038 14.2 3.7 2.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 KND88598.1 - 0.0032 17.3 0.0 0.01 15.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND88598.1 - 0.037 13.4 0.0 0.097 12.0 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF605 PF04652.11 KND88598.1 - 5.9 6.1 11.5 9.8 5.4 8.0 1.3 1 0 0 1 1 1 0 Vta1 like Zds_C PF08632.5 KND88599.1 - 6.1e-30 102.3 1.0 1.3e-29 101.3 0.7 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Complex1_30kDa PF00329.14 KND88600.1 - 3.1e-35 120.5 0.1 4.5e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Sec3_C PF09763.4 KND88601.1 - 8.7e-233 774.4 0.5 1.1e-232 774.0 0.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KND88601.1 - 2.1e-30 104.4 0.0 5.1e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KND88601.1 - 0.027 14.6 0.0 0.027 14.6 0.0 2.6 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Vps52 PF04129.7 KND88601.1 - 0.083 11.4 1.5 0.15 10.5 0.1 1.9 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF2018 PF09442.5 KND88601.1 - 0.096 13.2 0.1 0.35 11.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) HECT PF00632.20 KND88603.1 - 9.3e-78 261.5 0.0 1.7e-77 260.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KND88603.1 - 3.3e-05 23.5 2.1 0.32 11.2 0.0 4.7 4 1 1 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KND88603.1 - 0.012 16.1 0.3 2.5 8.6 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat DUF2013 PF09431.5 KND88603.1 - 0.032 13.9 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) CLASP_N PF12348.3 KND88603.1 - 0.045 13.1 0.2 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.18 KND88603.1 - 0.069 13.0 6.8 0.92 9.4 0.1 4.6 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.6 KND88603.1 - 0.35 8.9 9.7 0.035 12.2 3.3 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 E1_dh PF00676.15 KND88604.1 - 2.1e-83 279.5 0.0 2.6e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 KND88604.1 - 0.00026 19.9 0.0 0.00051 18.9 0.0 1.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 KND88604.1 - 0.00088 18.8 0.1 0.011 15.3 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KND88604.1 - 0.055 12.3 0.0 0.32 9.8 0.0 2.1 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase Fe-ADH PF00465.14 KND88605.1 - 5.2e-101 337.9 0.0 6.4e-101 337.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KND88605.1 - 2.3e-13 50.0 0.0 2.1e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KND88605.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein F-box PF00646.28 KND88606.1 - 0.0014 18.2 2.7 0.0023 17.5 0.3 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KND88606.1 - 0.02 14.6 2.8 0.045 13.4 1.9 1.6 1 0 0 1 1 1 0 F-box-like Gpi16 PF04113.9 KND88607.1 - 7.8e-231 766.9 0.0 8.8e-231 766.8 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Patatin PF01734.17 KND88608.1 - 0.00078 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Pkinase PF00069.20 KND88609.1 - 2.7e-14 52.9 0.0 3.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88609.1 - 6.5e-06 25.4 0.0 8.9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND88609.1 - 5e-05 22.4 0.0 7.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND88609.1 - 7.5e-05 22.5 0.3 0.00012 21.8 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND88609.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KND88609.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Gly_transf_sug PF04488.10 KND88610.1 - 4.7e-06 26.9 0.0 8.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KND88610.1 - 0.064 11.7 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.10 KND88611.1 - 6.5e-11 42.5 0.0 1.4e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RskA PF10099.4 KND88611.1 - 6.4 6.4 8.3 4.8 6.8 0.4 2.7 3 0 0 3 3 3 0 Anti-sigma-K factor rskA TFIIA PF03153.8 KND88612.1 - 0.0028 17.6 17.0 0.0034 17.3 11.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nuc_deoxyrib_tr PF05014.10 KND88613.1 - 0.038 13.8 0.0 0.055 13.3 0.0 1.3 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DUF3043 PF11241.3 KND88614.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TPR_12 PF13424.1 KND88615.1 - 6.6e-09 35.5 11.0 1.6e-05 24.7 2.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KND88615.1 - 1.9e-08 33.9 5.3 0.013 15.4 0.1 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND88615.1 - 5.4e-08 33.2 6.1 0.0069 17.0 0.2 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND88615.1 - 9.2e-08 31.3 6.3 0.28 11.0 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KND88615.1 - 4.7e-07 30.0 2.2 3.2 8.1 0.1 5.0 2 1 3 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KND88615.1 - 3.4e-06 27.1 2.9 0.0064 16.5 0.3 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KND88615.1 - 3.7e-05 23.2 3.7 0.078 12.6 0.3 4.6 2 1 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KND88615.1 - 0.00048 19.8 4.6 20 5.3 0.0 5.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND88615.1 - 0.00069 20.0 4.5 11 6.9 0.1 4.6 3 1 1 4 4 3 0 Tetratricopeptide repeat Syntaxin-18_N PF10496.4 KND88615.1 - 0.0025 17.6 4.0 0.62 9.9 0.0 3.7 1 1 3 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus DGCR6 PF07324.6 KND88615.1 - 0.0033 16.9 1.8 0.0062 16.0 1.2 1.5 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein TPR_8 PF13181.1 KND88615.1 - 0.0044 16.6 0.7 12 5.9 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3860 PF12976.2 KND88615.1 - 0.01 15.5 0.3 3.7 7.4 0.0 3.5 1 1 2 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) TPR_6 PF13174.1 KND88615.1 - 0.02 15.3 0.0 63 4.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KND88615.1 - 0.025 14.6 6.5 8.5 6.5 0.1 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat Bombinin PF05298.6 KND88615.1 - 0.035 13.5 2.1 5.3 6.5 0.1 2.6 1 1 0 2 2 2 0 Bombinin KNOX1 PF03790.8 KND88615.1 - 0.054 12.8 1.0 3.9 6.8 0.0 3.2 2 1 1 3 3 3 0 KNOX1 domain 2OG-FeII_Oxy_2 PF13532.1 KND88616.1 - 1.5e-31 109.7 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KND88616.1 - 0.0059 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.20 KND88617.1 - 2.9e-66 223.8 0.0 3.9e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 KND88618.1 - 7.3e-34 115.9 7.9 1.8e-28 98.6 1.0 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KND88618.1 - 9.4e-07 28.8 7.2 1.5e-06 28.1 1.9 4.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND88618.1 - 2.5e-06 27.4 5.9 2.9e-06 27.2 0.7 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF629 PF04780.7 KND88618.1 - 0.0027 16.3 0.0 0.0054 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF629) SnoaL_2 PF12680.2 KND88618.1 - 0.009 16.4 0.1 0.036 14.4 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain zf-C2H2_6 PF13912.1 KND88618.1 - 1.6 8.7 10.2 7.3 6.6 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger SKG6 PF08693.5 KND88619.1 - 0.00074 18.7 0.5 0.00074 18.7 0.4 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KND88619.1 - 0.0019 17.7 3.3 0.0028 17.2 2.3 1.3 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 KND88619.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KND88619.1 - 0.018 13.3 0.0 0.032 12.4 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3697 PF12478.3 KND88619.1 - 0.073 12.7 0.6 0.16 11.6 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 adh_short PF00106.20 KND88620.1 - 1.4e-24 86.8 0.5 2e-24 86.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND88620.1 - 3.3e-14 53.2 0.0 3.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND88620.1 - 1.1e-06 28.4 0.2 1.9e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KND88620.1 - 3.2e-05 23.4 1.5 5.3e-05 22.7 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3320 PF11784.3 KND88620.1 - 0.00092 18.6 0.6 0.0016 17.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3320) NAD_binding_10 PF13460.1 KND88620.1 - 0.0015 18.5 0.2 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KND88620.1 - 0.0055 16.7 0.2 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.16 KND88620.1 - 0.0088 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND88620.1 - 0.0094 15.2 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 KND88620.1 - 0.021 13.9 0.2 0.09 11.9 0.1 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KND88620.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UPF0051 PF01458.12 KND88620.1 - 0.092 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) RmlD_sub_bind PF04321.12 KND88620.1 - 0.092 11.6 0.1 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.13 KND88620.1 - 0.098 12.2 0.6 0.21 11.2 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PIR PF00399.14 KND88621.1 - 1.7e-25 87.3 52.6 4.6e-07 28.9 0.7 8.3 8 0 0 8 8 8 7 Yeast PIR protein repeat AA_permease PF00324.16 KND88622.1 - 1.1e-118 396.6 39.9 1.3e-118 396.4 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND88622.1 - 8.9e-34 116.7 42.1 1.2e-33 116.3 29.2 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 KND88623.1 - 3.6e-14 52.2 2.6 4.2e-14 52.0 0.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain ChaB PF06150.7 KND88623.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 ChaB zf-U1 PF06220.7 KND88624.1 - 6.7e-06 25.5 1.6 1.4e-05 24.5 1.1 1.6 1 0 0 1 1 1 1 U1 zinc finger GET2 PF08690.5 KND88624.1 - 0.062 12.5 1.5 0.083 12.1 1.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 TMEM51 PF15345.1 KND88624.1 - 4.3 6.9 8.7 0.37 10.4 2.7 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 Glyco_hydro_47 PF01532.15 KND88626.1 - 3.5e-126 421.4 0.0 4e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.9 KND88627.1 - 3.5e-30 103.5 0.0 5.6e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KND88627.1 - 0.11 12.6 0.5 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain Ndc80_HEC PF03801.8 KND88628.1 - 4.4e-59 198.4 0.1 9.1e-59 197.4 0.1 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Ribosomal_L7Ae PF01248.21 KND88628.1 - 1.3e-20 72.6 1.9 3.4e-20 71.3 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WASH_WAHD PF11945.3 KND88628.1 - 0.0071 15.6 1.9 0.016 14.5 1.3 1.5 1 0 0 1 1 1 1 WAHD domain of WASH complex FliJ PF02050.11 KND88628.1 - 0.015 15.3 22.1 0.016 15.2 2.1 3.5 2 1 1 3 3 3 0 Flagellar FliJ protein DUF1664 PF07889.7 KND88628.1 - 0.033 13.9 0.4 0.033 13.9 0.3 4.8 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 KND88628.1 - 0.059 13.1 30.2 1.4 8.6 1.0 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Filament PF00038.16 KND88628.1 - 0.51 9.7 43.2 0.098 12.1 13.9 2.7 3 0 0 3 3 3 0 Intermediate filament protein DUF4510 PF14971.1 KND88628.1 - 3.5 7.7 10.4 0.2 11.7 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) NPV_P10 PF05531.7 KND88628.1 - 4.6 7.5 9.3 8.8 6.6 0.2 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lactamase_B_2 PF12706.2 KND88629.1 - 8.1e-39 133.1 0.0 1.1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KND88629.1 - 1.9e-08 34.1 0.0 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KND88629.1 - 6.3e-05 22.7 0.5 0.00062 19.4 0.1 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Ribosomal_L35Ae PF01247.13 KND88630.1 - 1.2e-37 127.5 0.8 3.5e-29 100.4 0.1 2.0 2 0 0 2 2 2 2 Ribosomal protein L35Ae RimM PF01782.13 KND88630.1 - 0.0098 15.8 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 RimM N-terminal domain VMA21 PF09446.5 KND88631.1 - 1.2e-14 53.9 8.6 1.8e-14 53.3 5.9 1.3 1 0 0 1 1 1 1 VMA21-like domain OPT PF03169.10 KND88631.1 - 0.025 13.0 0.1 0.03 12.7 0.1 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF2406 PF10295.4 KND88632.1 - 6.1e-19 68.3 0.3 6.1e-19 68.3 0.2 2.9 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) SNF2_N PF00176.18 KND88633.1 - 9.9e-59 198.5 0.3 1.6e-58 197.9 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND88633.1 - 2.1e-13 49.9 0.0 1e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UBA PF00627.26 KND88633.1 - 0.00017 21.2 0.8 0.00092 18.9 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain DEAD PF00270.24 KND88633.1 - 0.0029 17.1 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3890 PF13029.1 KND88633.1 - 0.11 12.5 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) Ank_2 PF12796.2 KND88634.1 - 2.6e-29 101.4 0.0 3.5e-15 56.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND88634.1 - 3.5e-26 89.6 0.1 1.7e-06 27.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 KND88634.1 - 8.8e-20 68.8 0.5 3.4e-05 23.6 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KND88634.1 - 1e-19 70.4 0.5 0.0003 21.2 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND88634.1 - 1.9e-18 66.0 0.3 1.2e-07 31.6 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Myb_DNA-bind_6 PF13921.1 KND88635.1 - 0.0011 19.0 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.1 KND88635.1 - 6.8 7.0 8.4 1.1 9.5 3.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GDPD PF03009.12 KND88636.1 - 1e-42 146.3 0.0 7.9e-41 140.2 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KND88636.1 - 6.9e-27 93.6 0.8 2.2e-09 37.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND88636.1 - 6e-21 73.1 7.7 4.4e-07 29.3 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KND88636.1 - 2.5e-20 72.4 2.3 9.4e-06 26.0 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND88636.1 - 9.9e-18 63.7 3.5 0.0022 18.1 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88636.1 - 3.5e-17 60.7 2.8 0.00021 21.2 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.14 KND88636.1 - 3.7e-11 43.3 0.2 1.2e-09 38.3 0.0 2.4 1 1 2 3 3 3 1 SPX domain FAD_binding_3 PF01494.14 KND88638.1 - 2.3e-22 79.5 0.5 7.2e-22 77.9 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain PhageMin_Tail PF10145.4 KND88638.1 - 0.14 11.7 0.7 0.21 11.2 0.5 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein DIT1_PvcA PF05141.7 KND88639.1 - 2.8e-85 286.0 0.0 3.8e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 KND88639.1 - 4.1e-25 88.9 0.1 8e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_4 PF01565.18 KND88640.1 - 4.2e-30 104.0 3.1 7.3e-30 103.2 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND88640.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KND88641.1 - 5.3e-13 49.2 1.5 4.8e-12 46.1 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND88641.1 - 7.1e-06 25.8 0.2 9.8e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND88641.1 - 0.0032 16.9 0.1 0.02 14.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND88641.1 - 0.67 9.9 3.5 3.5 7.5 2.4 2.1 1 1 0 1 1 1 0 NADH(P)-binding DEAD PF00270.24 KND88642.1 - 1.5e-40 138.4 0.0 4.7e-40 136.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND88642.1 - 2.5e-23 81.7 0.1 7.6e-23 80.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KND88642.1 - 0.025 13.3 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain TPR_MLP1_2 PF07926.7 KND88643.1 - 7.5e-30 103.3 23.4 7.5e-30 103.3 16.2 17.6 8 5 9 18 18 18 9 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KND88643.1 - 3.1e-06 27.1 21.5 3.1e-06 27.1 14.9 18.8 8 5 11 19 19 19 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KND88643.1 - 5.6e-05 21.8 54.8 5.6e-05 21.8 38.0 8.7 4 3 0 6 6 6 3 Weak chloroplast movement under blue light DUF904 PF06005.7 KND88643.1 - 0.00019 21.6 7.4 0.00019 21.6 5.1 25.5 12 10 5 18 18 18 4 Protein of unknown function (DUF904) Lactamase_B_2 PF12706.2 KND88644.1 - 4.8e-11 42.5 0.0 9.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 KND88644.1 - 2e-06 27.8 0.0 5.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 KND88644.1 - 3.2e-05 23.6 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KND88644.1 - 0.011 15.4 0.1 0.031 14.0 0.0 1.7 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase p450 PF00067.17 KND88645.1 - 3e-25 88.6 0.0 3.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KND88646.1 - 1.7e-31 109.3 0.0 2.3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3435 PF11917.3 KND88648.1 - 1.1e-09 37.5 0.0 1.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sel1 PF08238.7 KND88650.1 - 7.3e-35 118.6 29.2 4.9e-05 23.8 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.10 KND88652.1 - 1.4e-290 964.2 0.1 2e-290 963.6 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KND88652.1 - 1.5e-17 63.9 4.7 7.2e-17 61.7 3.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND88652.1 - 3.5e-13 49.9 0.0 6.6e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KND88652.1 - 1e-12 47.6 0.1 5.1e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KND88652.1 - 3.6e-06 26.3 0.0 0.00024 20.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KND88652.1 - 0.0032 17.1 0.0 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2207 PF09972.4 KND88652.1 - 1.6 7.2 5.7 11 4.4 2.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 KND88653.1 - 3.2e-66 223.1 0.0 4.5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88653.1 - 2.1e-39 135.1 0.0 2.9e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND88653.1 - 2.7e-08 33.1 0.0 6.6e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 KND88653.1 - 4.5e-08 32.9 0.0 4.2e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 KND88653.1 - 0.00084 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 KND88654.1 - 3.2e-28 98.1 0.3 6.6e-28 97.1 0.2 1.5 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) IncA PF04156.9 KND88654.1 - 0.42 10.1 1.4 0.9 9.0 1.0 1.5 1 0 0 1 1 1 0 IncA protein SBDS PF01172.13 KND88656.1 - 1e-24 86.1 0.1 1.2e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ion_trans_2 PF07885.11 KND88657.1 - 3.8e-34 116.2 25.6 4e-18 64.8 3.3 3.5 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KND88657.1 - 1 8.6 19.0 0.037 13.2 2.9 3.1 2 1 0 3 3 3 0 Ion transport protein Zip PF02535.17 KND88657.1 - 2.1 7.2 11.1 4.9 6.0 7.7 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.9 KND88657.1 - 6.5 6.2 11.3 13 5.2 7.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Glyco_hydro_2_C PF02836.12 KND88660.1 - 5.5e-94 314.4 0.8 8.5e-94 313.7 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KND88660.1 - 6.7e-50 168.9 0.8 1.1e-49 168.1 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 KND88660.1 - 4e-39 134.2 0.0 7.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Peptidase_M20 PF01546.23 KND88660.1 - 6.1e-20 71.5 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KND88660.1 - 1.9e-13 49.7 4.4 0.0047 16.7 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Glyco_hydro_2 PF00703.16 KND88660.1 - 7.8e-11 42.4 0.0 1.8e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 M20_dimer PF07687.9 KND88660.1 - 0.00099 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Invas_SpaK PF03519.9 KND88660.1 - 0.021 14.6 0.1 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Invasion protein B family Peptidase_M28 PF04389.12 KND88660.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M42 PF05343.9 KND88660.1 - 0.065 11.9 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Barstar PF01337.13 KND88660.1 - 0.097 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) 4HBT_3 PF13622.1 KND88662.1 - 5.1e-45 154.2 4.2 5.9e-45 153.9 2.9 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_2 PF00891.13 KND88663.1 - 5e-27 94.6 0.0 6.4e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KND88663.1 - 0.14 12.7 0.0 0.49 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 KND88665.1 - 4.8e-52 172.0 17.3 1.1e-08 34.6 1.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KND88665.1 - 3.8e-09 36.1 0.7 7.5e-09 35.1 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND88665.1 - 1.2e-08 34.3 0.1 2.8e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KND88665.1 - 0.0027 17.2 0.7 5 6.5 0.1 3.3 1 1 3 4 4 4 3 PQQ-like domain Nup160 PF11715.3 KND88665.1 - 0.0074 14.4 9.7 3.1 5.8 0.1 5.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Pkinase PF00069.20 KND88666.1 - 3.2e-25 88.7 0.0 5.5e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88666.1 - 1.6e-14 53.6 0.0 2.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 KND88666.1 - 8.8e-12 45.2 0.0 0.00026 21.2 0.0 3.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND88666.1 - 5.4e-10 38.5 0.2 0.095 12.5 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KND88666.1 - 5.9e-07 29.8 0.1 3 8.4 0.0 5.5 4 1 2 6 6 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88666.1 - 7.3e-07 28.8 0.2 5 7.6 0.0 5.8 7 0 0 7 7 5 1 Ankyrin repeat Kdo PF06293.9 KND88666.1 - 0.00072 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.1 KND88666.1 - 0.0012 19.0 0.4 0.13 12.5 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) APH PF01636.18 KND88666.1 - 0.0098 15.6 1.7 0.019 14.7 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND88666.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KND88666.1 - 0.31 9.7 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Abhydrolase_6 PF12697.2 KND88667.1 - 0.00054 19.9 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KND88667.1 - 0.00083 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KND88667.1 - 0.0053 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Kdo PF06293.9 KND88667.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2305 PF10230.4 KND88667.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Pkinase PF00069.20 KND88667.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF3089 PF11288.3 KND88667.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) CdhD PF03599.11 KND88667.1 - 0.15 10.5 0.0 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit PGAP1 PF07819.8 KND88667.1 - 0.18 11.4 0.0 0.45 10.0 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein DUF726 PF05277.7 KND88667.1 - 0.27 10.0 0.0 0.41 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Ank_2 PF12796.2 KND88668.1 - 7.3e-54 180.0 0.0 2.7e-21 75.6 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KND88668.1 - 7.1e-50 164.4 8.1 8e-12 44.3 0.0 7.5 6 1 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KND88668.1 - 2.2e-38 129.9 1.2 1.6e-13 50.7 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88668.1 - 2.2e-35 117.1 0.3 5e-07 29.3 0.0 8.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KND88668.1 - 3.5e-35 119.2 5.9 2.4e-10 40.3 0.0 5.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.7 KND88668.1 - 6.3e-10 38.9 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND88668.1 - 1.2e-07 31.8 0.7 4.2e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND88668.1 - 3.1e-06 27.3 0.0 9.2e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KND88668.1 - 0.0032 16.5 0.2 0.098 11.6 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.17 KND88668.1 - 0.044 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KND88668.1 - 0.091 12.9 0.0 0.39 10.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KND88668.1 - 0.15 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 KND88668.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Glyco_hydro_18 PF00704.23 KND88670.1 - 5.2e-76 256.3 2.5 7.2e-76 255.8 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KND88670.1 - 1.4e-09 37.7 16.5 1.4e-09 37.7 11.5 4.5 4 1 1 5 5 5 2 Chitin recognition protein Patched PF02460.13 KND88672.1 - 5.2e-70 236.3 11.9 3.3e-44 151.0 0.1 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KND88672.1 - 6.9e-49 165.2 4.1 6.9e-49 165.2 2.8 3.0 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KND88672.1 - 6.1e-07 28.4 37.4 0.00024 19.9 9.8 2.8 2 1 0 2 2 2 2 MMPL family Mannosyl_trans2 PF04188.8 KND88673.1 - 2e-62 211.5 3.5 4.1e-62 210.5 2.4 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) MR_MLE_C PF13378.1 KND88674.1 - 8.5e-20 70.7 0.1 1.1e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KND88674.1 - 2.9e-13 50.1 0.2 1.2e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 KND88674.1 - 0.0078 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.11 KND88674.1 - 0.0088 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Hexapep PF00132.19 KND88675.1 - 1.1e-10 40.5 10.7 5.7e-07 28.7 1.0 3.7 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KND88675.1 - 0.0013 18.2 12.4 0.18 11.3 3.1 3.7 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.12 KND88676.1 - 2.9e-46 156.9 0.0 4.3e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KND88676.1 - 3.4e-18 64.5 1.1 3.4e-18 64.5 0.8 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KND88676.1 - 4.1e-09 36.2 0.0 1.2e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.9 KND88677.1 - 1.3e-18 67.0 0.0 3.2e-18 65.8 0.0 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Smr PF01713.16 KND88678.1 - 9.8e-09 35.2 0.9 3.7e-08 33.4 0.4 2.2 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 KND88678.1 - 0.0027 17.1 0.1 0.0062 16.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 KND88678.1 - 0.016 15.0 0.0 0.062 13.1 0.0 2.0 1 0 0 1 1 1 0 UBA/TS-N domain Pkinase PF00069.20 KND88679.1 - 5.2e-21 74.9 0.0 2e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND88679.1 - 0.00034 19.7 0.0 0.31 10.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase SET PF00856.23 KND88680.1 - 3.1e-10 40.5 0.0 1.9e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 KND88680.1 - 2.5e-08 33.4 3.9 2.8e-07 30.0 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 KND88680.1 - 5.7e-05 23.6 12.1 0.0014 19.2 0.4 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND88680.1 - 0.0017 18.6 1.0 0.85 10.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND88680.1 - 0.015 15.6 4.8 3.7 7.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND88680.1 - 0.035 14.0 7.8 4.9 7.3 0.1 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_18 PF13512.1 KND88680.1 - 0.035 14.1 0.6 18 5.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KND88680.1 - 0.047 13.8 0.6 0.36 10.9 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KND88680.1 - 0.073 13.7 4.7 57 4.7 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat YfiO PF13525.1 KND88680.1 - 0.17 11.2 2.3 3.7 6.9 0.0 2.8 3 0 0 3 3 3 0 Outer membrane lipoprotein Amidohydro_3 PF07969.6 KND88682.1 - 6.5e-25 88.1 0.2 9.5e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family D-aminoacyl_C PF07908.7 KND88682.1 - 3.3e-15 55.1 0.0 8.3e-15 53.8 0.0 1.8 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_5 PF13594.1 KND88682.1 - 1.9e-12 46.8 0.2 4.7e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KND88682.1 - 7.9e-09 35.9 1.9 4.4e-05 23.6 0.3 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KND88682.1 - 0.00081 19.1 0.1 0.56 9.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family APH PF01636.18 KND88684.1 - 7.3e-07 29.1 0.1 1.9e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1985 PF09331.6 KND88684.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) HEAT_EZ PF13513.1 KND88685.1 - 6e-22 77.4 8.1 4.6e-07 30.1 0.2 9.3 11 2 1 12 12 12 4 HEAT-like repeat HEAT PF02985.17 KND88685.1 - 3.5e-20 70.2 2.4 0.0025 17.7 0.0 8.2 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 KND88685.1 - 2e-18 66.4 5.8 0.0033 17.6 0.0 6.7 5 1 2 7 7 7 5 HEAT repeats Adaptin_N PF01602.15 KND88685.1 - 3.6e-06 25.6 0.0 0.36 9.0 0.0 4.5 3 2 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KND88685.1 - 6.8e-06 26.3 0.0 0.12 12.8 0.0 4.8 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KND88685.1 - 3.1e-05 23.8 0.0 0.00023 21.0 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KND88685.1 - 0.0016 18.2 0.3 1.4 8.8 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KND88685.1 - 0.0017 18.2 0.1 5.8 6.7 0.0 4.8 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KND88685.1 - 0.036 14.0 1.1 26 4.8 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion DUF747 PF05346.6 KND88686.1 - 3.4e-127 424.0 7.2 4.3e-127 423.7 5.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DLH PF01738.13 KND88686.1 - 3.9e-26 91.6 0.2 5.6e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND88686.1 - 1.3e-05 24.9 0.1 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 KND88688.1 - 5.5e-32 110.9 0.0 5.7e-31 107.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88688.1 - 3.9e-21 75.2 0.0 7.6e-21 74.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KND88688.1 - 0.0041 16.2 0.1 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myosin_tail_1 PF01576.14 KND88688.1 - 0.017 12.8 5.2 0.025 12.3 3.6 1.1 1 0 0 1 1 1 0 Myosin tail ADIP PF11559.3 KND88688.1 - 0.084 12.7 3.1 0.43 10.4 2.9 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMEM192 PF14802.1 KND88688.1 - 0.13 11.0 0.1 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 TMEM192 family FlxA PF14282.1 KND88688.1 - 0.13 12.1 0.2 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.3 KND88688.1 - 0.34 10.7 5.8 1.2 9.0 2.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MMR_HSR1 PF01926.18 KND88689.1 - 3.4e-17 62.4 0.0 6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KND88689.1 - 2.6e-07 30.5 0.0 0.0011 18.8 0.3 2.4 1 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KND88689.1 - 0.00036 20.0 0.0 0.0024 17.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KND88689.1 - 0.0014 18.5 0.5 0.13 12.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KND88689.1 - 0.0032 16.6 0.1 0.0095 15.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KND88689.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 KND88689.1 - 0.033 13.4 0.1 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 KND88689.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 KND88689.1 - 0.05 12.7 0.0 0.12 11.4 0.0 1.7 1 1 0 1 1 1 0 AIG1 family Septin PF00735.13 KND88689.1 - 0.061 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin IIGP PF05049.8 KND88689.1 - 0.21 10.3 0.0 0.43 9.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) zf-C3HC PF07967.8 KND88690.1 - 2.3e-35 121.2 0.1 2.1e-31 108.4 0.1 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KND88690.1 - 3.8e-25 87.5 0.4 1.2e-24 85.9 0.1 2.0 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 KND88690.1 - 0.031 14.6 0.0 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain SRP40_C PF05022.7 KND88691.1 - 1.1e-21 77.1 4.5 3.4e-21 75.5 1.9 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain TFIIA PF03153.8 KND88691.1 - 0.47 10.2 37.6 0.64 9.8 26.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit A_deaminase_N PF08451.6 KND88692.1 - 0.0031 17.5 0.1 0.018 15.0 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal A_deaminase PF00962.17 KND88692.1 - 0.068 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Pkinase PF00069.20 KND88694.1 - 3e-37 128.1 0.1 5.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88694.1 - 1.2e-22 80.2 0.1 1.7e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KND88694.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CDK2AP PF09806.4 KND88695.1 - 4.2 7.5 7.2 5.1 7.2 5.0 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3437 PF11919.3 KND88696.1 - 2.3e-32 110.5 0.2 1.2e-31 108.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KND88696.1 - 0.0027 17.6 0.1 24 5.3 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Tim17 PF02466.14 KND88697.1 - 6e-33 113.6 5.5 7.5e-33 113.2 3.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SE PF08491.5 KND88698.1 - 2.8e-87 292.0 0.0 3.8e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KND88698.1 - 4.4e-09 35.7 0.6 2.9e-08 33.0 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KND88698.1 - 5.6e-09 35.5 1.6 2.7e-05 23.3 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KND88698.1 - 9.6e-06 25.5 0.3 2.2e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND88698.1 - 4.4e-05 22.6 0.0 7.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KND88698.1 - 9.2e-05 21.4 0.4 0.00054 18.9 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KND88698.1 - 0.00018 20.5 0.4 0.038 12.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KND88698.1 - 0.00027 19.9 0.3 0.00043 19.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KND88698.1 - 0.00046 20.5 0.1 0.0012 19.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND88698.1 - 0.00048 19.3 0.4 0.00085 18.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KND88698.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KND88698.1 - 0.0026 17.4 0.1 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KND88698.1 - 0.0027 17.6 0.4 0.0091 15.8 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KND88698.1 - 0.0036 16.7 0.1 0.0066 15.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KND88698.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KND88698.1 - 0.024 14.4 0.8 0.072 12.9 0.4 1.9 2 0 0 2 2 2 0 ThiF family HI0933_like PF03486.9 KND88698.1 - 0.048 12.1 0.1 0.068 11.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KND88698.1 - 0.17 11.9 0.0 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.22 KND88700.1 - 8.3e-60 198.5 0.0 8.3e-21 73.5 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF221 PF02714.10 KND88702.1 - 5.8e-96 321.1 22.7 5.8e-96 321.1 15.7 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND88702.1 - 5.1e-41 139.8 0.1 5.1e-41 139.8 0.1 3.7 3 1 2 5 5 5 2 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KND88702.1 - 1.2e-18 66.7 0.0 2.9e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KND88702.1 - 2.9e-10 40.5 7.2 5.3e-05 23.6 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) APH PF01636.18 KND88703.1 - 4.5e-14 52.7 0.0 1.5e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88703.1 - 0.00059 19.4 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KND88703.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 KND88704.1 - 1.4e-15 57.7 0.0 1.8e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND88704.1 - 4e-06 26.5 0.0 1e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND88704.1 - 0.014 14.7 0.1 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KND88704.1 - 0.014 14.5 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain EcKinase PF02958.15 KND88704.1 - 0.034 13.2 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase PEMT PF04191.8 KND88705.1 - 9.6e-56 186.4 9.7 5.7e-34 116.4 1.3 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase eIF3g PF12353.3 KND88706.1 - 4.6e-46 155.8 2.2 8.3e-46 155.0 1.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KND88706.1 - 1.3e-15 56.7 0.0 2.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88706.1 - 3.4e-12 46.1 0.1 7.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88706.1 - 4e-07 29.7 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIDO PF06119.9 KND88706.1 - 0.15 12.8 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 Nidogen-like IBR PF01485.16 KND88707.1 - 2e-14 53.2 36.9 2e-08 33.9 5.5 3.4 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KND88707.1 - 6.5e-05 22.6 6.8 6.5e-05 22.6 4.7 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND88707.1 - 0.00018 21.4 8.3 0.00018 21.4 5.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND88707.1 - 0.025 14.2 6.6 0.09 12.5 4.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF1460 PF07313.7 KND88707.1 - 0.03 13.5 0.6 0.051 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) zf-C3HC4_4 PF15227.1 KND88707.1 - 0.12 12.2 13.9 0.029 14.2 1.7 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF676 PF05057.9 KND88708.1 - 1.9e-43 148.2 0.0 3.2e-28 98.5 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND88708.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KND88708.1 - 0.028 14.0 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Mlo PF03094.10 KND88708.1 - 0.26 9.3 0.0 0.43 8.6 0.0 1.2 1 0 0 1 1 1 0 Mlo family Zn_clus PF00172.13 KND88709.1 - 2.1e-09 37.1 8.0 2.1e-09 37.1 5.5 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND88709.1 - 5.7e-06 25.4 0.1 8.1e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.4 KND88710.1 - 3.6e-72 243.3 0.0 6.9e-72 242.3 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 KND88710.1 - 0.093 13.0 3.2 2.8 8.3 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain AAA_25 PF13481.1 KND88711.1 - 2e-08 33.8 0.2 1.3e-07 31.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KND88711.1 - 2.6e-07 29.9 0.0 4.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 KND88711.1 - 1.2e-05 24.7 0.0 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad51 PF08423.6 KND88711.1 - 3.8e-05 22.7 0.0 0.00029 19.8 0.0 2.4 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 KND88711.1 - 3.9e-05 22.8 0.3 0.00011 21.4 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA PF00004.24 KND88711.1 - 9.7e-05 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KND88711.1 - 0.00015 21.4 0.5 0.0051 16.5 0.0 2.8 3 0 0 3 3 3 1 Part of AAA domain PhoH PF02562.11 KND88711.1 - 0.00018 20.7 0.1 0.0047 16.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Arch_ATPase PF01637.13 KND88711.1 - 0.00031 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase DnaB_C PF03796.10 KND88711.1 - 0.0011 17.9 0.0 0.083 11.7 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain IPT PF01745.11 KND88711.1 - 0.0029 16.8 0.2 0.0052 15.9 0.1 1.4 1 0 0 1 1 1 1 Isopentenyl transferase AAA_24 PF13479.1 KND88711.1 - 0.0048 16.4 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 KND88711.1 - 0.0083 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 KND88711.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KND88711.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND88711.1 - 0.026 14.6 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KND88711.1 - 0.029 14.3 0.0 0.075 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Zot PF05707.7 KND88711.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NB-ARC PF00931.17 KND88711.1 - 0.062 12.1 0.1 0.097 11.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KND88711.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KND88711.1 - 0.099 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KND88711.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain zf-H2C2_2 PF13465.1 KND88712.1 - 1.3e-07 31.5 11.0 3.4e-06 27.0 2.4 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KND88712.1 - 2.8e-05 24.1 13.6 0.001 19.2 2.9 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND88712.1 - 0.0015 18.7 12.3 0.0052 17.0 0.9 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger DUF2225 PF09986.4 KND88712.1 - 0.35 10.2 0.7 0.87 8.9 0.4 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TIM21 PF08294.6 KND88713.1 - 8.4e-45 151.9 0.0 1e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KND88713.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Glycos_transf_2 PF00535.21 KND88716.1 - 9.9e-23 80.6 0.0 1.9e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KND88716.1 - 4.3e-09 36.5 0.1 2.6e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase like family 2 CPSase_L_D2 PF02786.12 KND88717.1 - 6.8e-112 371.8 0.8 2.4e-84 281.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KND88717.1 - 1.4e-45 155.0 0.0 3.2e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KND88717.1 - 1.6e-45 153.8 0.0 4.3e-45 152.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 KND88717.1 - 1.3e-43 148.0 0.1 9.2e-43 145.3 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KND88717.1 - 7.9e-42 141.8 0.0 9.2e-21 74.0 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KND88717.1 - 1.5e-41 141.0 0.1 4.1e-41 139.6 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 KND88717.1 - 1.7e-35 122.2 0.0 4.7e-35 120.7 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 KND88717.1 - 4.3e-34 117.8 0.5 3.5e-20 72.5 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KND88717.1 - 2.3e-23 81.9 0.1 3.7e-22 78.0 0.0 3.0 3 0 0 3 3 3 1 MGS-like domain ATPgrasp_Ter PF15632.1 KND88717.1 - 1.5e-21 76.5 0.0 3.6e-10 39.1 0.0 4.4 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KND88717.1 - 2.4e-15 56.2 0.5 2e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KND88717.1 - 5.4e-15 55.3 1.7 1.3e-06 28.0 0.2 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 KND88717.1 - 3.8e-07 29.7 0.6 1.7e-05 24.4 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.9 KND88717.1 - 6.2e-05 22.9 1.0 0.27 11.0 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 KND88717.1 - 0.0041 16.5 0.1 0.011 15.1 0.1 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 KND88717.1 - 0.015 14.8 0.7 1.3 8.5 0.0 3.0 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SMK-1 PF04802.10 KND88718.1 - 8e-79 263.6 0.1 1.6e-78 262.6 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Shadoo PF14999.1 KND88718.1 - 0.033 14.0 10.3 0.093 12.5 7.1 1.7 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Hex_IIIa PF02455.11 KND88718.1 - 0.98 8.0 5.8 2.1 6.9 4.0 1.5 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Chorion_2 PF03964.10 KND88718.1 - 8.4 7.0 10.3 2.1 8.9 4.1 2.2 2 0 0 2 2 2 0 Chorion family 2 Kelch_5 PF13854.1 KND88719.1 - 4.4e-12 45.6 2.4 1.4e-11 44.1 0.5 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 KND88719.1 - 3.2e-08 33.4 2.9 9.4e-07 28.8 0.2 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 KND88719.1 - 4.4e-07 29.5 4.1 0.063 13.0 0.1 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KND88719.1 - 0.0004 19.8 6.4 0.12 11.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif DUF4448 PF14610.1 KND88719.1 - 0.0007 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DAG1 PF05454.6 KND88719.1 - 0.0042 16.3 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Kelch_6 PF13964.1 KND88719.1 - 0.17 12.0 10.3 0.22 11.7 0.6 4.6 3 3 1 4 4 4 0 Kelch motif CDC73 PF05179.9 KND88721.1 - 1.5e-46 158.9 0.0 2.9e-46 158.0 0.0 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 KND88722.1 - 3.2e-35 120.7 1.7 4.7e-35 120.2 0.2 2.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 KND88722.1 - 3.5e-25 87.5 0.2 6.6e-21 73.8 0.0 3.3 3 1 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3742 PF12553.3 KND88723.1 - 0.11 12.9 1.7 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) AAA_16 PF13191.1 KND88725.1 - 1.1e-16 61.3 0.1 2.4e-15 57.0 0.0 2.6 2 1 0 2 2 1 1 AAA ATPase domain PHD PF00628.24 KND88725.1 - 8.2e-11 41.4 7.1 1.5e-10 40.6 4.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KND88725.1 - 1.9e-09 36.6 1.9 1.9e-09 36.6 1.3 1.6 2 0 0 2 2 1 1 PHD-finger AAA PF00004.24 KND88725.1 - 2.6e-09 37.3 0.0 5.6e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND88725.1 - 8.9e-09 35.5 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KND88725.1 - 4.7e-06 26.3 0.0 2.4e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KND88725.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 KND88725.1 - 0.00034 19.7 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 KND88725.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KND88725.1 - 0.0042 16.0 0.0 0.0083 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 KND88725.1 - 0.0045 16.4 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain FYVE_2 PF02318.11 KND88725.1 - 0.0061 16.4 0.9 0.015 15.2 0.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_30 PF13604.1 KND88725.1 - 0.0091 15.5 0.0 0.057 12.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KND88725.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain C1_1 PF00130.17 KND88725.1 - 0.011 15.4 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_19 PF13245.1 KND88725.1 - 0.012 15.3 0.2 0.043 13.5 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_25 PF13481.1 KND88725.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KND88725.1 - 0.027 14.1 0.1 0.096 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KND88725.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KND88725.1 - 0.029 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 KND88725.1 - 0.03 13.8 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 KND88725.1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KND88725.1 - 0.036 13.3 0.0 0.083 12.1 0.0 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ArgK PF03308.11 KND88725.1 - 0.039 12.7 0.0 0.098 11.4 0.0 1.6 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 KND88725.1 - 0.04 14.1 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 KND88725.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KND88725.1 - 0.059 12.5 0.0 0.059 12.5 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.7 KND88725.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 KND88725.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KND88725.1 - 0.12 13.2 0.0 0.26 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KND88725.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KND88725.1 - 0.12 12.1 0.0 0.71 9.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.21 KND88725.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 KND88725.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein G-alpha PF00503.15 KND88725.1 - 0.22 10.1 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ResIII PF04851.10 KND88725.1 - 0.24 11.2 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LtrA PF06772.6 KND88726.1 - 2.8e-05 23.2 26.8 8.5e-05 21.6 18.6 1.8 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Bystin PF05291.6 KND88727.1 - 2.8e-125 417.2 0.0 3.9e-125 416.7 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 KND88728.1 - 6.7e-67 224.7 0.0 1.7e-66 223.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KND88728.1 - 1.6e-23 82.0 1.3 3.3e-23 81.0 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 KND88728.1 - 0.011 13.9 0.0 0.053 11.7 0.0 2.0 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 KND88728.1 - 0.025 14.8 0.0 0.49 10.6 0.0 2.9 2 2 0 2 2 2 0 HEAT repeats VacJ PF04333.8 KND88728.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 VacJ like lipoprotein Arm_2 PF04826.8 KND88728.1 - 0.069 12.2 0.3 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Armadillo-like HEAT PF02985.17 KND88728.1 - 0.12 12.4 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat WD40 PF00400.27 KND88729.1 - 7.1e-21 73.2 3.6 1.2e-06 28.1 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Pro_isomerase PF00160.16 KND88729.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldo_ket_red PF00248.16 KND88730.1 - 2.1e-59 200.6 0.0 6.9e-59 198.9 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family Peptidase_S26 PF10502.4 KND88731.1 - 0.0031 17.0 0.0 0.067 12.7 0.0 2.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KND88731.1 - 0.038 13.6 0.7 0.17 11.5 0.5 2.0 1 1 0 1 1 1 0 Peptidase S24-like EIF_2_alpha PF07541.7 KND88732.1 - 1.7e-35 121.2 0.0 3.4e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KND88732.1 - 4.3e-13 49.1 0.7 9.8e-13 48.0 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain ArfGap PF01412.13 KND88734.1 - 1.4e-36 124.8 0.2 3e-36 123.7 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 KND88734.1 - 0.015 14.9 2.5 0.017 14.7 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) ADH_zinc_N PF00107.21 KND88735.1 - 7.9e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND88735.1 - 0.00013 21.6 0.0 0.00065 19.4 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SDP_N PF12278.3 KND88735.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal Nol1_Nop2_Fmu PF01189.12 KND88736.1 - 4.8e-30 104.9 0.0 4.3e-19 68.9 0.0 3.7 4 0 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KND88736.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GTP1_OBG PF01018.17 KND88737.1 - 4.6e-40 136.8 1.2 4.9e-29 101.0 2.1 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KND88737.1 - 1.5e-20 73.2 0.0 2.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND88737.1 - 2.4e-06 26.9 0.0 5.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KND88737.1 - 0.0031 16.3 0.0 0.21 10.3 0.0 2.2 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 KND88737.1 - 0.015 14.7 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KND88737.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 KND88737.1 - 0.11 11.7 0.0 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Mitofilin PF09731.4 KND88739.1 - 0.14 10.7 50.0 0.69 8.4 29.5 2.4 2 1 0 2 2 2 0 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.7 KND88739.1 - 1.3 8.8 5.2 3 7.6 0.2 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 KND88739.1 - 2.3 7.1 9.5 0.43 9.5 3.9 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Occludin_ELL PF07303.8 KND88739.1 - 8 7.2 37.7 0.28 11.9 2.4 4.9 2 1 3 5 5 5 0 Occludin homology domain RNA_pol_Rpb5_C PF01191.14 KND88740.1 - 2.4e-34 116.7 0.3 1.7e-33 114.0 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KND88740.1 - 9.7e-28 96.4 0.0 1.7e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KND88740.1 - 0.081 12.7 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease TFCD_C PF12612.3 KND88742.1 - 3e-32 111.6 0.7 1e-31 109.8 0.2 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KND88742.1 - 0.25 11.5 10.6 4.9 7.4 0.0 6.0 7 0 0 7 7 7 0 HEAT repeat Glyco_hydro_76 PF03663.9 KND88743.1 - 5.5e-46 157.6 12.3 2.8e-45 155.3 8.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Exonuc_VIII PF06630.6 KND88743.1 - 0.023 14.0 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII DUF4445 PF14574.1 KND88743.1 - 0.056 11.6 0.0 0.096 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) SH3_9 PF14604.1 KND88744.1 - 5.1e-12 45.1 0.4 2.6e-10 39.7 0.1 2.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KND88744.1 - 0.86 9.0 3.4 1.4 8.3 1.7 1.8 2 0 0 2 2 2 0 SH3 domain DUF3608 PF12257.3 KND88745.1 - 5.9e-20 71.3 0.2 7.3e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DUF3608 PF12257.3 KND88746.1 - 1.8e-39 135.3 0.0 3e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KND88746.1 - 1.1e-23 82.7 0.0 2.3e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.11 KND88747.1 - 4.5e-29 101.2 27.3 4.5e-29 101.2 19.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cation_efflux PF01545.16 KND88748.1 - 2.6e-73 246.5 3.2 3.1e-73 246.3 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KND88748.1 - 7.3e-10 38.3 0.9 1.2e-09 37.6 0.7 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Iso_dh PF00180.15 KND88750.1 - 2.8e-79 266.6 0.0 1.1e-50 172.5 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase AAA_17 PF13207.1 KND88751.1 - 4.5e-06 27.4 0.1 0.00011 23.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND88751.1 - 0.00019 21.3 0.0 0.00051 19.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND88751.1 - 0.00059 20.1 0.0 0.0071 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KND88751.1 - 0.0012 17.9 0.1 0.0044 16.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 KND88751.1 - 0.013 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 KND88751.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 KND88751.1 - 0.019 14.9 0.1 0.075 13.0 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KND88751.1 - 0.045 14.0 0.0 0.097 12.9 0.0 1.6 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KND88751.1 - 0.058 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KND88751.1 - 0.064 13.1 0.0 0.21 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 KND88751.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 KND88751.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KND88751.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KND88751.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 KND88751.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain FNIP_N PF14636.1 KND88752.1 - 9.9e-33 113.4 0.3 9.9e-33 113.4 0.2 3.4 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus DEAD PF00270.24 KND88753.1 - 1.3e-44 151.6 0.0 1.1e-43 148.7 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND88753.1 - 6e-23 80.4 0.8 1.8e-21 75.8 0.0 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KND88753.1 - 7.4e-20 70.5 3.0 1.9e-19 69.2 2.1 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 KND88753.1 - 0.00036 20.4 0.0 0.0011 18.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CTDII PF01556.13 KND88754.1 - 1.3e-27 95.4 0.3 3.9e-21 74.7 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KND88754.1 - 1e-23 82.8 2.3 2.3e-23 81.6 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KND88754.1 - 2e-10 40.5 19.1 4.3e-10 39.5 13.3 1.6 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 KND88755.1 - 1.1e-14 53.8 1.4 1.1e-14 53.8 1.0 2.2 2 0 0 2 2 2 1 DnaJ domain Xpo1 PF08389.7 KND88756.1 - 1.4e-23 83.4 0.1 6.6e-22 78.0 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein Adaptin_N PF01602.15 KND88756.1 - 0.0024 16.2 0.2 0.16 10.2 0.0 2.6 2 0 0 2 2 2 2 Adaptin N terminal region RRM_1 PF00076.17 KND88757.1 - 4.9e-22 77.3 0.0 6.4e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88757.1 - 3.8e-16 58.8 0.0 1.7e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88757.1 - 9.6e-05 22.1 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 KND88758.1 - 6e-47 159.8 0.0 8.5e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KND88758.1 - 2.3e-21 76.4 0.1 3.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MOR2-PAG1_N PF14222.1 KND88759.1 - 2.9e-218 726.0 0.0 5.8e-218 725.0 0.0 1.5 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KND88759.1 - 3.7e-90 302.2 0.0 7.9e-90 301.1 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KND88759.1 - 5.7e-34 116.9 4.7 1.1e-18 66.3 0.1 3.7 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.1 KND88759.1 - 0.00076 19.7 0.1 1.8 8.9 0.0 5.8 7 1 0 7 7 7 1 HEAT repeats HEAT PF02985.17 KND88759.1 - 0.011 15.7 3.7 2.9 8.2 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KND88759.1 - 0.21 12.1 1.4 2 9.0 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat PC_rep PF01851.17 KND88761.1 - 1.8e-21 75.0 15.8 2.2e-06 27.5 0.1 9.1 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KND88761.1 - 2.3e-10 40.5 0.2 0.0021 18.3 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KND88761.1 - 0.039 14.0 0.0 22 5.4 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat RIO1 PF01163.17 KND88762.1 - 2e-40 138.1 0.2 1.8e-39 135.0 0.1 2.1 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KND88762.1 - 4.9e-32 109.8 0.1 8.5e-32 109.0 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.9 KND88762.1 - 8.5e-07 28.2 0.0 0.045 12.8 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND88762.1 - 3.9e-06 26.7 0.3 0.016 14.9 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family TFIIA PF03153.8 KND88762.1 - 0.0047 16.8 6.9 0.0061 16.5 4.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 KND88762.1 - 0.044 12.5 18.8 0.06 12.0 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BSP_II PF05432.6 KND88762.1 - 0.045 13.0 13.7 0.071 12.3 9.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.6 KND88762.1 - 0.081 12.7 5.7 0.15 11.8 4.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.7 KND88762.1 - 0.096 11.8 15.1 0.15 11.1 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_60s PF00428.14 KND88762.1 - 0.12 12.7 13.8 0.21 11.9 9.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Prothymosin PF03247.9 KND88762.1 - 0.12 12.5 21.6 0.21 11.7 15.0 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family BUD22 PF09073.5 KND88762.1 - 0.45 9.5 14.5 0.64 9.0 10.0 1.1 1 0 0 1 1 1 0 BUD22 Striatin PF08232.7 KND88762.1 - 0.51 10.6 3.3 0.92 9.8 2.3 1.3 1 0 0 1 1 1 0 Striatin family Nop14 PF04147.7 KND88762.1 - 0.63 7.8 15.9 0.84 7.4 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KND88762.1 - 0.74 8.2 14.1 0.96 7.8 9.8 1.1 1 0 0 1 1 1 0 Daxx Family Nop25 PF09805.4 KND88762.1 - 0.76 9.8 10.7 1.4 8.9 7.4 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nucleoplasmin PF03066.10 KND88762.1 - 1 8.8 14.8 2 7.9 10.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 KND88762.1 - 2.3 8.1 19.0 3.8 7.3 13.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.8 KND88762.1 - 2.7 7.5 13.9 5.1 6.6 9.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KND88762.1 - 3.2 6.9 13.0 4.8 6.3 9.0 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 KND88762.1 - 6.7 5.7 8.8 14 4.7 6.1 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.7 KND88762.1 - 6.9 6.3 12.9 10 5.7 8.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CLASP_N PF12348.3 KND88763.1 - 6.3e-132 437.9 0.0 2.3e-88 295.3 0.0 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 KND88763.1 - 8.5e-05 22.3 0.0 0.63 10.2 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KND88763.1 - 0.0073 16.5 3.6 1.5 9.1 1.7 4.3 3 1 0 3 3 3 1 HEAT repeats RhoGAP PF00620.22 KND88764.1 - 6.8e-45 152.3 0.0 6.8e-45 152.3 0.0 2.4 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.17 KND88764.1 - 1.9e-13 50.2 16.7 6.3e-09 35.7 1.1 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.7 KND88764.1 - 0.036 13.4 8.0 5.1 6.5 0.5 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain SlyX PF04102.7 KND88764.1 - 1.1 9.6 11.4 0.054 13.8 1.1 2.8 2 0 0 2 2 2 0 SlyX Zn-ribbon_8 PF09723.5 KND88764.1 - 1.5 8.8 17.9 0.53 10.2 0.8 4.0 4 0 0 4 4 4 0 Zinc ribbon domain Cytochrom_CIII PF02085.11 KND88764.1 - 6.2 6.9 8.6 17 5.5 6.0 1.7 1 0 0 1 1 1 0 Class III cytochrome C family DUF4210 PF13915.1 KND88765.1 - 1.7e-26 92.2 0.0 3.7e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KND88765.1 - 4.3e-23 80.9 0.3 9.3e-23 79.8 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.1 KND88766.1 - 1.7e-14 53.5 1.8 0.22 11.4 0.0 7.2 4 2 3 7 7 7 6 PPR repeat family PPR_3 PF13812.1 KND88766.1 - 4.7e-14 51.4 8.2 0.071 13.4 0.0 9.2 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 KND88766.1 - 1e-10 40.8 7.4 0.06 13.3 0.0 7.9 8 0 0 8 8 8 2 PPR repeat TPR_14 PF13428.1 KND88766.1 - 6.3e-08 32.5 8.7 9.4 7.1 0.0 9.6 9 1 1 10 10 10 1 Tetratricopeptide repeat PPR_1 PF12854.2 KND88766.1 - 1.8e-05 24.0 0.1 2.5 7.6 0.1 4.4 4 0 0 4 4 4 2 PPR repeat TPR_19 PF14559.1 KND88766.1 - 0.00037 20.7 4.3 7.8 6.9 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 KND88766.1 - 0.0098 15.6 0.2 0.83 9.3 0.0 2.3 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) ATP13 PF12921.2 KND88766.1 - 0.05 12.9 0.2 57 3.0 0.0 4.2 5 0 0 5 5 5 0 Mitochondrial ATPase expression rRNA_processing PF08524.6 KND88767.1 - 0.0021 17.8 34.8 0.045 13.5 7.4 2.2 1 1 1 2 2 2 2 rRNA processing Vfa1 PF08432.5 KND88767.1 - 5.9 6.8 21.1 4 7.4 5.9 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.20 KND88768.1 - 0.00012 21.3 0.3 0.044 12.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND88768.1 - 0.054 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3435 PF11917.3 KND88769.1 - 4.4e-40 137.6 0.0 5.3e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) RRF PF01765.14 KND88769.1 - 0.039 13.4 0.6 0.065 12.7 0.4 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Toxin_43 PF15604.1 KND88769.1 - 1.3 9.0 5.6 2.2 8.3 3.9 1.2 1 0 0 1 1 1 0 Putative toxin 43 TPR_10 PF13374.1 KND88770.1 - 2.3e-15 55.9 6.8 3e-07 30.1 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND88770.1 - 1.7e-11 43.9 0.3 0.00024 20.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND88770.1 - 1.5e-09 37.3 0.5 8.7e-07 28.5 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KND88770.1 - 7.2e-09 34.8 3.0 0.0013 18.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND88770.1 - 1e-06 28.0 4.3 0.0016 18.1 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND88770.1 - 1e-05 25.7 0.6 0.015 15.8 0.0 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND88770.1 - 3.5e-05 23.3 8.1 0.032 14.1 0.1 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND88770.1 - 3.7e-05 23.1 2.1 0.091 12.5 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND88770.1 - 0.0041 17.7 4.5 0.39 11.4 1.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 KND88770.1 - 0.02 15.3 0.9 2.6 8.7 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND88770.1 - 0.067 13.6 2.2 13 6.5 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3435 PF11917.3 KND88772.1 - 0.045 12.4 0.0 0.045 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) G-7-MTase PF12803.2 KND88772.1 - 0.089 11.9 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Mito_carr PF00153.22 KND88773.1 - 2e-62 206.9 0.0 6.3e-22 77.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.9 KND88774.1 - 3.8e-30 104.7 0.0 5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 KND88774.1 - 0.0034 17.4 0.9 0.0088 16.0 0.3 1.8 1 1 1 2 2 2 1 Methyltransferase domain Ribosomal_L23 PF00276.15 KND88775.1 - 5e-13 48.8 0.0 1.2e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 Spo7 PF03907.8 KND88778.1 - 3.4e-67 226.1 0.0 4.4e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF1880 PF08976.6 KND88778.1 - 0.24 11.5 2.8 0.43 10.7 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) Abhydrolase_6 PF12697.2 KND88779.1 - 2.6e-28 99.4 1.0 7.9e-28 97.8 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND88779.1 - 4.5e-15 55.8 0.0 4.6e-13 49.2 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND88779.1 - 4.1e-12 46.0 0.0 1.5e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KND88779.1 - 8.4e-06 25.0 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KND88779.1 - 0.00026 20.4 0.0 0.00072 19.0 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KND88779.1 - 0.00038 20.0 0.9 0.0076 15.8 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KND88779.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KND88779.1 - 0.043 13.3 0.0 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.3 KND88779.1 - 0.044 13.6 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Ser_hydrolase PF06821.8 KND88779.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF2305 PF10230.4 KND88779.1 - 0.22 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2360 PF10152.4 KND88779.1 - 4.8 7.4 8.5 15 5.8 3.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) NDT80_PhoG PF05224.7 KND88780.1 - 1.4e-41 142.5 0.0 2.6e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ABC_tran PF00005.22 KND88782.1 - 5.1e-45 153.1 1.9 5.5e-22 78.5 0.0 3.5 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KND88782.1 - 2.1e-14 54.1 0.9 1.4e-07 31.8 0.1 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KND88782.1 - 2.9e-09 36.4 6.3 0.042 13.0 0.0 4.8 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND88782.1 - 1.7e-08 33.8 0.5 0.00035 20.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KND88782.1 - 2.2e-08 34.9 0.2 0.0035 18.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_tran_2 PF12848.2 KND88782.1 - 1.8e-07 30.8 6.9 1.9e-07 30.8 3.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 KND88782.1 - 3.6e-07 30.2 0.6 0.00037 20.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KND88782.1 - 5.3e-07 29.8 0.3 0.079 13.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KND88782.1 - 6.3e-07 29.3 0.1 0.055 13.4 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase MobB PF03205.9 KND88782.1 - 1.2e-06 28.3 0.0 0.0075 15.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KND88782.1 - 3.8e-06 26.8 2.5 0.064 13.1 0.1 3.5 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 KND88782.1 - 8.6e-06 26.2 0.1 0.063 13.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KND88782.1 - 2.8e-05 23.3 0.2 0.084 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 KND88782.1 - 4e-05 22.5 1.9 0.043 12.5 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA_18 PF13238.1 KND88782.1 - 9.3e-05 22.7 4.3 0.12 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 KND88782.1 - 9.4e-05 22.6 0.1 0.021 15.0 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KND88782.1 - 0.0001 22.0 0.0 0.045 13.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KND88782.1 - 0.00029 20.8 10.7 0.013 15.5 1.7 3.5 2 2 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KND88782.1 - 0.0004 20.1 0.1 3.5 7.2 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.1 KND88782.1 - 0.00042 19.9 0.1 0.13 11.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KND88782.1 - 0.0014 18.1 3.3 0.26 10.6 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain Arch_ATPase PF01637.13 KND88782.1 - 0.0018 18.0 0.2 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KND88782.1 - 0.0024 17.3 0.6 0.23 10.9 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KND88782.1 - 0.0025 17.3 0.1 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 KND88782.1 - 0.0025 17.2 0.7 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KND88782.1 - 0.0028 17.5 0.0 3.4 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KND88782.1 - 0.0039 16.6 1.3 0.11 11.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND88782.1 - 0.0045 16.7 0.3 0.41 10.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KND88782.1 - 0.0077 16.0 5.0 0.49 10.1 0.0 2.9 3 1 0 3 3 2 1 Dynamin family AAA_23 PF13476.1 KND88782.1 - 0.008 16.5 20.9 0.17 12.1 2.9 3.9 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.12 KND88782.1 - 0.01 15.6 12.3 0.12 12.1 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function DUF87 DUF815 PF05673.8 KND88782.1 - 0.012 14.5 1.9 0.67 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KND88782.1 - 0.012 15.3 1.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KND88782.1 - 0.013 15.6 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 KND88782.1 - 0.014 14.8 0.1 1.9 7.9 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Arf PF00025.16 KND88782.1 - 0.027 13.6 0.3 1 8.6 0.1 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family MukB PF04310.7 KND88782.1 - 0.038 13.3 0.0 6.9 5.9 0.0 2.7 2 0 0 2 2 2 0 MukB N-terminal AAA_15 PF13175.1 KND88782.1 - 0.079 11.9 6.2 0.48 9.4 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain ABC_ATPase PF09818.4 KND88782.1 - 0.12 10.9 0.0 0.12 10.9 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Thymidylate_kin PF02223.12 KND88782.1 - 0.25 10.6 4.9 1.7 7.9 0.0 2.9 3 0 0 3 3 2 0 Thymidylate kinase AAA_13 PF13166.1 KND88782.1 - 0.64 8.4 16.2 0.4 9.0 0.0 4.0 3 1 1 4 4 4 0 AAA domain NB-ARC PF00931.17 KND88782.1 - 3.8 6.2 9.2 1.6 7.5 0.0 3.0 4 0 0 4 4 3 0 NB-ARC domain DUF1770 PF08589.5 KND88782.1 - 5.9 7.5 5.9 2.5 8.7 0.9 2.7 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1770) TRM PF02005.11 KND88783.1 - 3.9e-100 335.4 0.0 2.8e-89 299.6 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DAGK_cat PF00781.19 KND88783.1 - 3.1e-06 26.6 0.0 6.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Methyltransf_26 PF13659.1 KND88783.1 - 0.046 13.7 0.1 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KND88783.1 - 0.21 10.9 0.0 0.63 9.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain NMO PF03060.10 KND88784.1 - 6.3e-70 235.9 1.5 7.7e-70 235.6 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KND88784.1 - 2.4e-08 33.2 1.4 5.7e-08 32.0 1.0 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KND88784.1 - 0.00042 19.2 4.1 0.00069 18.5 2.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KND88784.1 - 0.002 17.1 0.5 0.0032 16.4 0.3 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Pterin_bind PF00809.17 KND88785.1 - 9.8e-66 221.1 0.0 1.8e-65 220.2 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KND88785.1 - 2.2e-40 137.3 0.0 4.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) BIR PF00653.16 KND88786.1 - 1e-41 141.1 3.3 1.5e-20 73.3 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Snf7 PF03357.16 KND88786.1 - 0.031 13.6 2.3 1.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Snf7 DIOX_N PF14226.1 KND88788.1 - 4.2e-22 78.8 0.0 7.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND88788.1 - 5.6e-21 74.6 0.0 1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Svf1 PF08622.5 KND88789.1 - 1.2e-126 422.1 0.0 1.6e-126 421.6 0.0 1.2 1 0 0 1 1 1 1 Svf1-like Mit_KHE1 PF10173.4 KND88790.1 - 3e-61 206.5 0.1 4.2e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Med2 PF11214.3 KND88790.1 - 0.15 12.1 0.5 0.28 11.2 0.1 1.6 2 0 0 2 2 2 0 Mediator complex subunit 2 Utp21 PF04192.7 KND88791.1 - 1.2e-77 260.2 2.1 2e-77 259.4 0.4 2.1 2 1 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KND88791.1 - 2.7e-25 87.2 22.0 6.2e-08 32.2 0.2 8.6 8 1 0 8 8 8 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KND88791.1 - 2e-08 32.9 0.0 4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KND88791.1 - 7.2e-07 27.7 0.3 0.051 11.7 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KND88791.1 - 0.013 14.2 0.0 1.1 7.9 0.0 2.7 1 1 0 1 1 1 0 Nup133 N terminal like His_Phos_2 PF00328.17 KND88792.1 - 2.3e-125 418.5 0.1 3.1e-125 418.1 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KND88792.1 - 7.6e-06 25.5 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FmdA_AmdA PF03069.10 KND88793.1 - 2.8e-47 161.1 0.0 2.9e-25 88.7 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family Acetyltransf_7 PF13508.1 KND88795.1 - 0.0042 17.2 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND88795.1 - 0.019 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KND88795.1 - 0.092 12.6 0.1 0.66 9.8 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain GATA PF00320.22 KND88796.1 - 4.9e-14 51.3 2.7 9.1e-14 50.5 1.9 1.5 1 0 0 1 1 1 1 GATA zinc finger Myosin_tail_1 PF01576.14 KND88796.1 - 0.00041 18.2 15.2 0.00041 18.2 10.6 1.7 2 0 0 2 2 2 1 Myosin tail ArfGap PF01412.13 KND88796.1 - 0.053 13.3 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Fmp27_WPPW PF10359.4 KND88796.1 - 0.1 11.0 11.9 0.024 13.0 4.5 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 KND88796.1 - 0.17 11.0 1.5 0.67 9.0 0.5 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Macoilin PF09726.4 KND88796.1 - 2.1 6.5 14.2 3 6.0 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein NinG PF05766.7 KND88796.1 - 2.7 7.6 12.5 0.22 11.2 1.3 2.9 2 1 1 3 3 3 0 Bacteriophage Lambda NinG protein DUF342 PF03961.8 KND88796.1 - 3.2 6.0 10.3 0.13 10.6 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Striatin PF08232.7 KND88796.1 - 4.3 7.6 21.4 1.8 8.8 2.2 3.2 2 1 1 3 3 3 0 Striatin family CENP-F_leu_zip PF10473.4 KND88796.1 - 4.3 7.1 23.5 0.033 14.0 2.1 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD40_alt PF14077.1 KND88796.1 - 5.7 6.6 6.0 20 4.9 0.0 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif ADIP PF11559.3 KND88796.1 - 6.3 6.6 26.1 0.62 9.9 10.8 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HEAT_2 PF13646.1 KND88797.1 - 4.3e-30 103.8 4.9 2.2e-15 56.7 0.1 4.0 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KND88797.1 - 4.5e-20 70.0 5.1 0.0026 18.0 0.0 7.0 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KND88797.1 - 1.5e-07 31.7 9.6 0.0071 16.8 0.7 4.9 2 2 1 3 3 3 3 HEAT-like repeat HEAT PF02985.17 KND88797.1 - 4.1e-07 29.5 5.2 0.65 10.2 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat MFS_1 PF07690.11 KND88798.1 - 1.8e-15 56.5 46.4 2.3e-07 29.8 11.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 KND88798.1 - 8e-05 21.0 12.0 0.00013 20.2 8.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KND88799.1 - 3.4e-59 199.8 0.7 5.1e-59 199.2 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KND88799.1 - 1.4e-10 40.8 5.6 0.00012 22.2 0.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND88799.1 - 2.3e-09 36.9 5.9 0.00057 20.0 0.5 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND88799.1 - 6.4 7.2 17.5 0.27 11.5 1.7 3.9 4 0 0 4 4 4 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.1 KND88800.1 - 1.6e-12 47.0 1.0 4.6e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Cut8_N PF14482.1 KND88800.1 - 0.12 12.3 1.0 0.85 9.6 0.7 2.1 1 1 0 1 1 1 0 Cut8 proteasome-binding domain GMC_oxred_N PF00732.14 KND88801.1 - 5.4e-31 107.8 0.0 3.8e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND88801.1 - 1.4e-30 106.5 0.0 4.4e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND88801.1 - 0.00072 18.5 0.0 0.0029 16.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KND88801.1 - 0.0032 17.5 0.1 1.9 8.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND88801.1 - 0.0065 16.3 0.2 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Med25_VWA PF11265.3 KND88801.1 - 0.0092 15.0 0.0 0.61 9.0 0.0 2.2 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A DAO PF01266.19 KND88801.1 - 0.014 14.3 0.2 0.055 12.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND88801.1 - 0.034 14.1 0.2 0.092 12.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KND88801.1 - 0.069 11.6 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KND88801.1 - 0.079 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KND88801.1 - 0.17 10.9 0.1 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pex2_Pex12 PF04757.9 KND88802.1 - 1.4e-55 188.2 6.0 1.9e-55 187.8 4.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region WSC PF01822.14 KND88803.1 - 3e-12 46.2 8.7 3e-12 46.2 6.0 1.9 2 0 0 2 2 2 1 WSC domain 4HBT PF03061.17 KND88805.1 - 8.7e-14 51.4 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KND88805.1 - 0.0094 15.7 0.3 0.02 14.6 0.0 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF4442 PF14539.1 KND88805.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Metallophos PF00149.23 KND88806.1 - 1.3e-08 34.5 8.9 1.5e-07 31.0 6.2 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND88806.1 - 5.3e-06 26.3 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.7 KND88807.1 - 2.2e-117 392.4 10.9 2.8e-117 392.1 7.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SLEI_Leptospira PF07620.6 KND88807.1 - 0.092 12.5 2.3 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 SLEI ParA PF10609.4 KND88808.1 - 1.1e-33 114.9 0.0 2e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KND88808.1 - 1.4e-13 50.6 0.0 2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KND88808.1 - 3.7e-05 23.7 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KND88808.1 - 0.00024 20.2 0.1 0.0016 17.5 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KND88808.1 - 0.0034 16.5 0.0 0.0096 15.0 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 KND88808.1 - 0.0036 16.5 0.0 0.81 8.8 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 KND88808.1 - 0.0038 16.4 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 KND88808.1 - 0.0055 16.3 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND88808.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain TF_Zn_Ribbon PF08271.7 KND88808.1 - 0.028 13.7 0.1 0.067 12.5 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Rad17 PF03215.10 KND88808.1 - 0.037 12.7 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KND88808.1 - 0.043 13.5 0.1 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 KND88808.1 - 0.046 12.6 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KND88808.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KND88808.1 - 0.16 11.5 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 KND88808.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E TFIIS_C PF01096.13 KND88809.1 - 9.3e-13 47.5 0.7 9.3e-13 47.5 0.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KND88809.1 - 2.6e-05 23.7 3.5 2.6e-05 23.7 2.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 KND88809.1 - 0.012 15.3 2.2 0.012 15.3 1.6 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 KND88809.1 - 0.049 13.0 13.8 2.1 7.9 0.0 4.1 3 1 0 3 3 3 0 A2L zinc ribbon domain NodZ PF05830.6 KND88809.1 - 0.084 11.4 0.1 0.093 11.2 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) zf-CSL PF05207.8 KND88809.1 - 0.1 12.0 0.1 0.1 12.0 0.1 3.2 2 2 1 3 3 3 0 CSL zinc finger ArfGap PF01412.13 KND88809.1 - 0.51 10.1 3.4 3.4 7.4 0.6 2.1 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf DAN PF03045.10 KND88809.1 - 0.56 9.6 4.5 0.18 11.2 0.4 1.9 2 0 0 2 2 2 0 DAN domain Lar_restr_allev PF14354.1 KND88809.1 - 0.75 10.1 10.0 2.9 8.2 0.2 3.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 KND88809.1 - 1.4 8.5 0.1 1.4 8.5 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KND88809.1 - 4 7.1 10.1 0.24 11.0 0.6 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-CHY PF05495.7 KND88809.1 - 4.1 7.6 9.4 3.2 7.9 0.7 2.3 2 1 0 2 2 2 0 CHY zinc finger GFA PF04828.9 KND88809.1 - 7.4 6.6 9.3 41 4.2 1.1 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nipped-B_C PF12830.2 KND88810.1 - 1.9e-45 154.8 0.0 2.7e-44 151.0 0.1 2.6 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KND88810.1 - 2.9e-10 39.8 4.1 5.4e-10 39.0 0.8 2.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KND88810.1 - 7.3e-05 22.5 1.5 0.23 11.6 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KND88810.1 - 0.004 17.0 0.0 0.085 12.6 0.0 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KND88810.1 - 0.0056 16.9 0.8 0.38 11.0 0.0 4.0 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KND88810.1 - 0.49 10.9 4.6 7.8 7.1 0.0 4.9 4 1 1 5 5 5 0 HEAT-like repeat Ras PF00071.17 KND88812.1 - 1.1e-55 187.4 0.1 1.7e-55 186.8 0.1 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KND88812.1 - 2.5e-17 63.4 0.0 3.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KND88812.1 - 7.1e-07 28.8 0.1 3.7e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KND88812.1 - 2.1e-06 27.0 0.0 9.7e-06 24.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 KND88812.1 - 0.022 14.3 0.7 0.94 8.9 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KND88812.1 - 0.054 12.6 0.1 0.082 12.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KND88812.1 - 0.056 12.8 0.1 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 KND88812.1 - 0.059 13.3 0.0 0.099 12.6 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase VGCC_beta4Aa_N PF12052.3 KND88812.1 - 0.097 12.5 0.5 0.35 10.7 0.3 2.0 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Gtr1_RagA PF04670.7 KND88812.1 - 0.13 11.4 0.1 0.2 10.7 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KND88812.1 - 0.16 11.2 0.1 0.69 9.1 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B MoCF_biosynth PF00994.19 KND88813.1 - 1e-35 122.2 0.0 1.7e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 KND88814.1 - 1.5e-09 37.8 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Na_Ca_ex PF01699.19 KND88816.1 - 6.9e-44 148.8 28.7 5.4e-23 81.1 7.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2034 PF10356.4 KND88818.1 - 2.1e-31 108.5 0.0 4.3e-17 61.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KND88818.1 - 3.6e-08 33.1 0.0 5.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Lon_C PF05362.8 KND88819.1 - 2.6e-64 216.2 0.0 4.5e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KND88819.1 - 9.9e-37 126.6 0.0 1.8e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KND88819.1 - 1.5e-21 76.9 0.0 3.6e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND88819.1 - 1.4e-06 28.0 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KND88819.1 - 1.6e-06 27.6 0.0 4.3e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 KND88819.1 - 3e-06 27.2 0.0 8.9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KND88819.1 - 2.1e-05 24.6 0.0 0.00038 20.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND88819.1 - 2.8e-05 24.1 0.2 0.0035 17.3 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_PrkA PF08298.6 KND88819.1 - 7.4e-05 21.5 0.0 0.00014 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KND88819.1 - 7.8e-05 23.4 0.0 0.00033 21.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND88819.1 - 0.00033 19.7 0.0 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KND88819.1 - 0.0095 16.2 0.6 0.032 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KND88819.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KND88819.1 - 0.016 14.5 0.2 0.095 12.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 KND88819.1 - 0.026 14.2 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 KND88819.1 - 0.028 13.1 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus DUF258 PF03193.11 KND88819.1 - 0.035 13.3 0.0 0.1 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KND88819.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 KND88819.1 - 0.059 12.8 0.2 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KND88819.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND88819.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND88819.1 - 0.42 10.9 3.4 0.73 10.1 0.0 2.7 3 0 0 3 3 2 0 ABC transporter tRNA-synt_1c PF00749.16 KND88820.1 - 0.29 9.7 6.7 0.034 12.8 1.7 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PBP_sp32 PF07222.7 KND88820.1 - 2.3 7.3 6.1 0.42 9.7 1.1 1.9 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF605 PF04652.11 KND88820.1 - 5.1 6.4 19.9 6.2 6.0 13.8 1.1 1 0 0 1 1 1 0 Vta1 like RTA1 PF04479.8 KND88821.1 - 2.8e-06 27.0 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Pkinase PF00069.20 KND88822.1 - 3.1e-10 39.6 0.3 3.1e-09 36.3 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88822.1 - 4.7e-10 38.9 0.0 5.6e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1490 PF07371.7 KND88823.1 - 0.078 12.9 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) RTA1 PF04479.8 KND88824.1 - 4.6e-17 62.2 7.0 6e-17 61.8 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3446 PF11928.3 KND88824.1 - 2.3 8.4 5.0 3.8 7.7 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) BSP PF04450.7 KND88825.1 - 1.5e-72 243.3 0.0 1.7e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KND88825.1 - 2.7e-07 30.6 0.2 3.1e-05 23.9 0.0 2.2 1 1 1 2 2 2 2 Peptidase MA superfamily 5-FTHF_cyc-lig PF01812.15 KND88828.1 - 4.3e-29 101.6 0.0 5.4e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.10 KND88829.1 - 7.2e-206 685.3 40.7 8.5e-206 685.1 28.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Toprim_4 PF13662.1 KND88830.1 - 0.097 12.6 0.0 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 Toprim domain Pkinase PF00069.20 KND88831.1 - 6.1e-63 212.3 0.0 5.5e-62 209.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88831.1 - 2.4e-26 92.3 0.0 2e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND88831.1 - 6.9e-06 25.2 0.0 1.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like UBA_2 PF08587.6 KND88831.1 - 0.0024 18.0 0.1 0.0063 16.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 KND88831.1 - 0.04 13.2 0.3 0.1 11.9 0.1 1.6 1 1 1 2 2 2 0 RIO1 family YukC PF10140.4 KND88831.1 - 0.042 12.4 0.0 0.064 11.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Orbi_VP6 PF01516.11 KND88832.1 - 1.3 8.0 7.2 1.8 7.5 5.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Yippee-Mis18 PF03226.9 KND88833.1 - 1.9e-19 69.4 0.0 2.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KND88833.1 - 0.0044 16.8 0.4 0.069 13.0 0.1 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I Rsm1 PF08600.5 KND88833.1 - 0.069 13.0 0.2 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Rsm1-like CHAT PF12770.2 KND88835.1 - 1.2e-10 40.9 0.4 2.2e-10 40.1 0.3 1.3 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.7 KND88835.1 - 0.00036 20.2 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KND88835.1 - 0.014 15.5 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Abhydrolase_2 PF02230.11 KND88836.1 - 6.9e-58 195.6 0.0 9e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KND88836.1 - 5.2e-12 45.7 0.2 2.2e-11 43.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND88836.1 - 4.7e-10 39.7 0.6 4.7e-07 29.9 0.4 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KND88836.1 - 5e-06 26.2 0.2 0.045 13.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 KND88836.1 - 4e-05 23.1 0.0 7.3e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KND88836.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KND88836.1 - 0.00024 20.3 0.5 0.017 14.3 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KND88836.1 - 0.00079 19.0 0.0 1.2 8.6 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.3 KND88836.1 - 0.012 14.6 0.0 0.54 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.5 KND88836.1 - 0.041 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF2974 PF11187.3 KND88836.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 KND88836.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_M20 PF01546.23 KND88837.1 - 2.4e-32 112.0 0.0 3.7e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND88837.1 - 2.5e-13 49.7 0.0 4.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF159 PF02586.9 KND88838.1 - 1e-50 172.1 0.0 2.5e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 DUF159 PF02586.9 KND88839.1 - 6.2e-55 185.9 0.0 9.9e-55 185.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 PA14_2 PF10528.4 KND88842.1 - 3.5e-11 43.0 0.5 5.7e-11 42.3 0.4 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KND88842.1 - 8.8e-06 25.4 0.1 2.4e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 PA14 domain Trehalase PF01204.13 KND88843.1 - 1.9e-188 627.2 0.0 2.3e-188 627.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KND88843.1 - 1.4e-17 62.7 0.3 2.3e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 KND88844.1 - 1.2e-276 917.9 0.4 1.4e-276 917.7 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KND88844.1 - 3.4e-11 42.8 0.0 3.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DNA_pol_E_B PF04042.11 KND88845.1 - 7.5e-60 201.7 0.0 1.1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFS_1 PF07690.11 KND88846.1 - 2.6e-25 88.8 30.2 1.1e-14 53.9 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND88846.1 - 1.3e-05 23.8 23.5 0.0013 17.1 7.2 2.6 1 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KND88846.1 - 0.0012 17.4 11.3 0.0012 17.4 7.9 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KND88846.1 - 0.0021 16.3 3.5 0.0021 16.3 2.4 2.3 2 1 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 KND88846.1 - 0.0029 16.1 15.5 0.021 13.2 4.9 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KND88846.1 - 0.1 12.4 3.7 1.4 8.7 0.1 3.1 3 0 0 3 3 3 0 MFS_1 like family RNA_pol_Rpb1_5 PF04998.12 KND88847.1 - 3.5e-85 285.6 0.0 7.1e-85 284.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KND88847.1 - 3.3e-82 276.4 0.0 4.7e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KND88847.1 - 9.1e-66 220.8 0.0 1.8e-65 219.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KND88847.1 - 1.8e-37 128.5 0.0 4e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KND88847.1 - 1.2e-30 105.3 0.1 2.9e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DDHD PF02862.12 KND88848.1 - 3.5e-71 239.6 0.0 3.5e-71 239.6 0.0 3.7 2 2 0 2 2 2 1 DDHD domain DUF3530 PF12048.3 KND88848.1 - 0.0027 16.7 1.2 0.0027 16.7 0.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3530) Abhydrolase_5 PF12695.2 KND88848.1 - 0.01 15.5 0.0 0.082 12.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 KND88848.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) OmpH PF03938.9 KND88848.1 - 0.25 11.2 17.5 0.3 11.0 4.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.2 KND88849.1 - 0.00045 20.4 0.0 0.0013 19.0 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) LexA_DNA_bind PF01726.11 KND88849.1 - 0.046 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain zf-RING_2 PF13639.1 KND88849.1 - 0.055 13.3 7.6 0.14 12.0 5.3 1.8 1 1 0 1 1 1 0 Ring finger domain Ank_3 PF13606.1 KND88849.1 - 0.15 12.3 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.25 KND88849.1 - 0.25 11.2 1.8 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat zf-C3HC4_2 PF13923.1 KND88849.1 - 1.7 8.7 5.8 0.32 11.0 1.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CH PF00307.26 KND88850.1 - 2.4e-61 204.4 0.0 7.9e-17 61.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KND88850.1 - 4.8e-05 23.4 0.3 0.00097 19.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KND88850.1 - 0.037 13.3 0.7 6 6.4 0.1 3.3 3 0 0 3 3 3 0 EF hand Rbsn PF11464.3 KND88851.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain DUF1192 PF06698.6 KND88851.1 - 0.092 12.5 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) RRM_1 PF00076.17 KND88853.1 - 1.4e-11 43.8 0.0 2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88853.1 - 3.5e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88853.1 - 5.2e-07 29.4 0.0 7.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND88853.1 - 0.00036 20.2 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_60s PF00428.14 KND88855.1 - 7.6 7.0 20.0 4.6e+02 1.2 13.9 2.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 KND88856.1 - 1.3e-12 47.1 1.3 2.2e-12 46.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KND88856.1 - 0.0042 17.3 0.5 0.019 15.2 0.4 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KND88856.1 - 0.0058 16.8 0.6 0.0058 16.8 0.4 3.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type RRM_1 PF00076.17 KND88857.1 - 1.4e-38 130.3 0.5 3.6e-18 64.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88857.1 - 7.5e-30 102.7 3.6 1.3e-15 57.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88857.1 - 9.6e-13 47.7 0.1 1.3e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND88857.1 - 0.00038 20.1 0.1 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KND88857.1 - 0.058 13.2 0.4 16 5.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif RabGAP-TBC PF00566.13 KND88858.1 - 1.1e-47 162.3 0.0 1.9e-47 161.4 0.0 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_90 PF05686.7 KND88859.1 - 2.6e-15 56.0 3.4 3.9e-13 48.8 0.0 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 90 RRM_1 PF00076.17 KND88861.1 - 4.5e-17 61.4 0.0 7e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88861.1 - 2.9e-15 56.0 0.0 4.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88861.1 - 2.5e-05 24.0 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 KND88861.1 - 0.0049 16.4 0.5 0.006 16.2 0.3 1.1 1 0 0 1 1 1 1 IncA protein NPV_P10 PF05531.7 KND88861.1 - 0.014 15.6 0.3 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CASP_C PF08172.7 KND88861.1 - 0.015 14.3 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal Packaging_FI PF14000.1 KND88861.1 - 0.018 15.2 0.6 0.025 14.7 0.4 1.4 1 0 0 1 1 1 0 DNA packaging protein FI V_ATPase_I PF01496.14 KND88861.1 - 0.026 12.4 0.1 0.029 12.2 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 KND88861.1 - 0.09 12.4 0.3 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 KND88861.1 - 0.094 12.2 5.2 0.15 11.6 3.6 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 KND88861.1 - 0.22 11.8 3.9 0.35 11.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) WD40_alt PF14077.1 KND88861.1 - 0.45 10.1 3.2 0.9 9.2 1.2 2.0 1 1 1 2 2 2 0 Alternative WD40 repeat motif GRP PF07172.6 KND88861.1 - 3 8.3 13.2 0.091 13.2 4.8 1.7 2 0 0 2 2 2 0 Glycine rich protein family cNMP_binding PF00027.24 KND88862.1 - 2.3e-42 142.7 0.0 1e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.6 KND88863.1 - 4.2e-42 144.1 0.2 5.9e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KND88863.1 - 0.012 15.3 3.8 0.022 14.4 2.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Peroxin-3 PF04882.7 KND88863.1 - 0.013 14.2 0.1 0.016 13.9 0.1 1.1 1 0 0 1 1 1 0 Peroxin-3 HABP4_PAI-RBP1 PF04774.10 KND88864.1 - 0.00068 20.1 0.8 0.001 19.5 0.6 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family SoxE PF06525.6 KND88865.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Mito_fiss_reg PF05308.6 KND88867.1 - 0.17 11.2 3.0 0.19 11.0 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Med15 PF09606.5 KND88867.1 - 3.9 5.5 6.8 4 5.5 4.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spc97_Spc98 PF04130.8 KND88868.1 - 5e-122 407.9 0.0 6.3e-122 407.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family SAGA-Tad1 PF12767.2 KND88869.1 - 1.9e-51 175.1 0.0 2.6e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SH2_2 PF14633.1 KND88870.1 - 2.5e-76 255.6 0.7 1.1e-75 253.5 0.0 2.2 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KND88870.1 - 8e-35 119.4 2.8 8e-35 119.4 1.9 4.6 5 0 0 5 5 5 1 Death-like domain of SPT6 YqgF PF14639.1 KND88870.1 - 9.4e-33 112.8 0.0 9.6e-32 109.6 0.0 2.6 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KND88870.1 - 2.1e-31 108.1 0.0 4.6e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 KND88870.1 - 1.5e-24 85.9 28.2 1.5e-24 85.9 19.6 6.6 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KND88870.1 - 9.5e-20 70.7 1.6 4.8e-19 68.5 1.1 2.2 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 KND88870.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 KND88870.1 - 3.5e-05 23.5 0.0 8.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KND88870.1 - 0.00052 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.14 KND88870.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain NUDIX PF00293.23 KND88871.1 - 2.6e-13 49.7 0.3 4.6e-13 48.9 0.2 1.3 1 1 0 1 1 1 1 NUDIX domain DUF92 PF01940.11 KND88872.1 - 2.5e-65 219.7 4.2 3.4e-65 219.3 2.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 ADIP PF11559.3 KND88873.1 - 2.4e-35 121.6 6.2 2.4e-35 121.6 4.3 2.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding RRP7 PF12923.2 KND88873.1 - 6.8e-30 103.7 10.1 6.8e-30 103.7 7.0 3.0 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) BAR PF03114.13 KND88875.1 - 2.1e-64 217.2 6.2 2.6e-64 216.8 4.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KND88875.1 - 6.9e-16 57.3 0.7 1.1e-15 56.7 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KND88875.1 - 6.8e-13 47.9 0.1 1.3e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND88875.1 - 5.2e-12 45.0 0.4 1.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 KND88875.1 - 0.45 9.7 8.6 3.1 6.9 0.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 KND88875.1 - 1 8.3 3.4 0.87 8.5 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein GTP_EFTU PF00009.22 KND88876.1 - 1.8e-47 161.2 0.0 2.9e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KND88876.1 - 1.6e-40 137.3 3.5 2.7e-40 136.5 2.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KND88876.1 - 6.5e-16 57.9 0.0 1.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND88876.1 - 8.1e-06 25.8 0.5 3.7e-05 23.7 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND88876.1 - 5.5e-05 23.0 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 KND88876.1 - 0.00014 21.3 0.0 0.0044 16.4 0.0 2.4 3 0 0 3 3 3 1 Ras family EFG_II PF14492.1 KND88876.1 - 0.00035 20.3 0.0 0.0011 18.7 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 KND88876.1 - 0.027 14.9 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein SRPRB PF09439.5 KND88876.1 - 0.074 12.2 0.0 0.2 10.8 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MIT PF04212.13 KND88877.1 - 3.9e-09 36.2 0.2 7.6e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DHquinase_I PF01487.10 KND88878.1 - 3.3e-30 105.3 0.0 5e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHquinase_I PF01487.10 KND88879.1 - 2.5e-12 46.9 0.0 3.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Glyoxalase_2 PF12681.2 KND88880.1 - 9.8e-09 35.7 0.0 1.7e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KND88880.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Mpp10 PF04006.7 KND88882.1 - 4.7e-88 296.0 61.4 4.3e-86 289.6 42.6 2.1 1 1 0 1 1 1 1 Mpp10 protein SHNi-TPR PF10516.4 KND88883.1 - 1e-11 43.8 0.1 2.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 KND88883.1 - 3.3e-07 30.1 2.8 0.0044 16.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND88883.1 - 6.8e-05 23.4 1.2 0.00092 19.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND88883.1 - 9.3e-05 21.9 0.8 0.0051 16.4 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KND88883.1 - 0.00096 18.8 2.7 0.43 10.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TrbI PF03743.9 KND88885.1 - 1.1 8.7 6.1 0.091 12.2 0.2 2.2 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein TrbI PF03743.9 KND88886.1 - 0.7 9.3 7.3 0.15 11.5 0.2 2.4 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein zf-RING_2 PF13639.1 KND88887.1 - 5.5e-09 35.7 3.5 9.3e-09 34.9 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND88887.1 - 7.6e-09 35.4 5.9 1.3e-08 34.6 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND88887.1 - 3.3e-08 33.0 3.6 5.7e-08 32.3 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND88887.1 - 6.7e-08 32.0 4.4 1.3e-07 31.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND88887.1 - 4e-07 29.6 3.7 7.1e-07 28.8 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND88887.1 - 1.5e-06 27.9 5.5 1.3e-05 24.9 3.9 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND88887.1 - 0.00018 21.1 3.2 0.0002 21.0 1.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KND88887.1 - 0.029 13.8 4.0 0.079 12.4 2.8 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 KND88887.1 - 0.26 11.4 1.6 0.67 10.1 1.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 KND88887.1 - 0.39 10.6 3.3 1.5 8.7 2.3 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Fungal_trans PF04082.13 KND88888.1 - 4e-25 88.1 0.2 6.8e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88888.1 - 0.027 14.3 11.7 0.053 13.4 8.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KND88888.1 - 1.5 8.1 7.1 2.6 7.3 4.9 1.3 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_114 PF03537.8 KND88889.1 - 9.2e-24 83.0 0.0 1.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Epiglycanin_C PF14654.1 KND88889.1 - 0.043 13.8 0.1 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region RskA PF10099.4 KND88889.1 - 0.054 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3693 PF12472.3 KND88889.1 - 0.14 11.7 0.2 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Phage related protein Spore_YtfJ PF09579.5 KND88889.1 - 4 7.3 6.7 8.7 6.2 4.7 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) LIP PF03583.9 KND88891.1 - 1.1e-80 270.9 0.1 1.6e-80 270.4 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KND88891.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND88891.1 - 0.029 13.6 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.11 KND88892.1 - 4.2e-36 124.3 17.4 6.3e-36 123.8 11.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.1 KND88892.1 - 0.7 10.0 10.3 0.4 10.8 0.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) RTA1 PF04479.8 KND88894.1 - 4e-12 46.1 3.6 6.1e-12 45.5 2.5 1.2 1 0 0 1 1 1 1 RTA1 like protein T5orf172 PF10544.4 KND88895.1 - 1.6e-15 57.3 1.0 3.8e-15 56.0 0.7 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KND88895.1 - 3.6e-11 43.3 2.4 9e-11 42.0 1.7 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF651 PF04895.7 KND88895.1 - 0.057 13.0 0.1 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) Arrestin_N PF00339.24 KND88896.1 - 4.8e-11 42.6 0.0 2.5e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain PGAP1 PF07819.8 KND88898.1 - 2.6e-06 27.1 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KND88898.1 - 5.3e-05 22.6 0.1 9.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KND88898.1 - 0.00015 21.6 5.3 0.00019 21.3 2.5 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 KND88898.1 - 0.0056 15.6 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 KND88898.1 - 0.067 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sulfate_transp PF00916.15 KND88899.1 - 0.00036 19.6 2.3 0.00036 19.6 1.6 2.8 2 1 0 2 2 2 1 Sulfate transporter family Ribosomal_L18p PF00861.17 KND88900.1 - 3.7e-42 143.3 0.2 3.7e-42 143.3 0.1 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KND88900.1 - 9.2e-34 115.8 8.2 9.2e-34 115.8 5.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Myb_DNA-bind_3 PF12776.2 KND88900.1 - 6.6 7.4 7.4 8.4 7.1 0.6 3.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain SAM_2 PF07647.12 KND88901.1 - 1.1e-10 41.2 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 KND88901.1 - 3e-10 39.5 0.1 7e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND88901.1 - 1.6e-08 33.8 0.0 3.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KND88901.1 - 6.1e-08 32.8 0.0 1.8e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KND88901.1 - 1.6e-05 25.1 0.2 3.9e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KND88901.1 - 0.00056 19.3 0.1 0.0015 17.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain adh_short PF00106.20 KND88903.1 - 2e-24 86.3 6.8 8.3e-23 81.1 4.7 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND88903.1 - 1.2e-16 61.2 0.0 2.2e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND88903.1 - 7.4e-08 32.2 4.1 1.7e-07 31.0 2.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND88903.1 - 0.036 13.5 0.2 0.069 12.5 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KND88903.1 - 0.037 13.1 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MR_MLE_C PF13378.1 KND88904.1 - 6.4e-21 74.4 0.0 1.9e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KND88904.1 - 6.4e-13 49.0 0.0 1.6e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KND88904.1 - 1.6e-10 41.0 0.0 3.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 KND88904.1 - 0.13 11.3 0.0 0.55 9.2 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase CFEM PF05730.6 KND88905.1 - 8e-07 28.7 8.1 1.1e-06 28.3 5.2 1.7 1 1 0 1 1 1 1 CFEM domain SKG6 PF08693.5 KND88905.1 - 0.0023 17.1 1.1 0.0023 17.1 0.8 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain ATG22 PF11700.3 KND88905.1 - 0.015 13.8 1.0 0.018 13.5 0.7 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like TFIIA PF03153.8 KND88905.1 - 0.3 10.9 5.0 0.35 10.7 3.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF566 PF04484.7 KND88905.1 - 3 7.2 15.2 4.1 6.8 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Tmemb_cc2 PF10267.4 KND88905.1 - 8.6 4.8 6.4 12 4.4 4.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ribosomal_L22 PF00237.14 KND88906.1 - 3.7e-14 52.5 0.0 6e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e HA2 PF04408.18 KND88907.1 - 5.6e-19 68.0 0.1 2.7e-18 65.8 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND88907.1 - 4.8e-11 42.3 0.1 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND88907.1 - 7.8e-11 41.7 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND88907.1 - 8e-09 35.7 0.3 2.9e-08 33.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.11 KND88907.1 - 2.2e-06 27.4 0.0 6e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold NB-ARC PF00931.17 KND88907.1 - 0.0064 15.3 0.4 0.016 14.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KND88907.1 - 0.017 15.4 0.0 0.051 13.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KND88907.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 KND88907.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 KND88907.1 - 0.15 11.2 0.0 0.46 9.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RRM_1 PF00076.17 KND88908.1 - 3.5e-46 154.6 0.1 4.3e-18 64.6 0.3 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND88908.1 - 3.1e-40 135.9 0.0 4.9e-14 52.0 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND88908.1 - 1.2e-18 66.6 0.0 1.6e-08 34.3 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND88908.1 - 1.2e-13 50.5 0.0 0.0061 16.3 0.0 3.7 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KND88908.1 - 1.9e-08 34.1 0.1 0.00018 21.3 0.1 3.7 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM PF05172.8 KND88908.1 - 0.00096 18.8 0.0 0.76 9.5 0.0 3.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 KND88908.1 - 0.019 14.4 0.0 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 Lsm interaction motif Hydrolase_6 PF13344.1 KND88909.1 - 2.1e-20 72.4 0.0 4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND88909.1 - 3.9e-12 45.6 0.0 4.3e-11 42.3 0.0 2.7 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 KND88909.1 - 0.015 15.4 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mitochondr_Som1 PF11093.3 KND88912.1 - 2.9e-08 33.4 0.1 3.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Pkinase PF00069.20 KND88913.1 - 5.3e-08 32.3 0.0 7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND88913.1 - 3.6e-06 26.2 0.0 1.3e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND88913.1 - 2.8e-05 23.9 0.2 0.08 12.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KND88913.1 - 6.8e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 KND88913.1 - 0.00097 18.2 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.16 KND88914.1 - 2.9e-08 32.8 0.0 4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 KND88915.1 - 2.6e-51 173.0 1.2 3.1e-51 172.8 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 KND88917.1 - 1.4e-06 27.2 7.9 1.7e-06 26.9 5.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CsbD PF05532.7 KND88918.1 - 1.1e-17 63.4 25.4 4.5e-12 45.4 1.5 4.2 2 1 1 3 3 3 2 CsbD-like Rick_17kDa_Anti PF05433.10 KND88918.1 - 5.8 6.6 11.4 5.1 6.8 2.5 3.2 3 0 0 3 3 3 0 Glycine zipper 2TM domain Aminotran_5 PF00266.14 KND88919.1 - 4.3e-93 311.9 0.0 5.2e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KND88919.1 - 1.1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KND88919.1 - 4.3e-06 26.0 0.0 1.1e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KND88919.1 - 0.0036 15.7 0.0 0.0054 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 KND88919.1 - 0.005 15.1 0.0 0.0073 14.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Lactamase_B_2 PF12706.2 KND88919.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CMD PF02627.15 KND88921.1 - 1.1e-10 41.2 0.1 2.8e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Oxidored_q6 PF01058.17 KND88922.1 - 3.7e-22 78.3 0.0 5.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.20 KND88923.1 - 4.4e-92 308.6 0.0 6e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KND88923.1 - 1e-33 114.8 21.4 1.5e-11 43.9 4.6 3.7 3 0 0 3 3 3 3 WW domain Mito_carr PF00153.22 KND88924.1 - 5.1e-75 247.2 3.3 1.9e-25 88.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 KND88925.1 - 2.9e-23 82.6 0.1 2.9e-23 82.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 MOSC PF03473.12 KND88926.1 - 5.5e-22 77.6 0.0 1.1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 KND88926.1 - 6.3e-12 45.0 0.3 1.2e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 KND88926.1 - 1.1e-09 38.7 0.0 3.3e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.9 KND88926.1 - 5e-05 22.9 0.1 9.1e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.7 KND88926.1 - 0.056 13.3 0.6 0.98 9.3 0.2 2.2 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Gln-synt_C PF00120.19 KND88927.1 - 4.3e-59 199.7 0.0 5.9e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KND88927.1 - 3.7e-16 58.4 0.0 2.1e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 Glutamine synthetase, beta-Grasp domain Acetyltransf_3 PF13302.1 KND88928.1 - 9.5e-21 74.4 0.0 1.2e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND88928.1 - 0.002 18.0 0.8 0.0093 15.8 0.5 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND88928.1 - 0.019 14.9 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND88928.1 - 0.023 14.7 0.0 0.082 12.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PEP-utilizers_C PF02896.13 KND88928.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain ArsA_ATPase PF02374.10 KND88930.1 - 3.3e-101 338.3 0.0 4.2e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KND88930.1 - 3.8e-15 55.8 0.1 1.1e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Acetyltransf_3 PF13302.1 KND88930.1 - 7.4e-11 42.3 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_31 PF13614.1 KND88930.1 - 2.9e-08 33.7 0.0 1.4e-07 31.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KND88930.1 - 7.7e-06 25.2 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Acetyltransf_1 PF00583.19 KND88930.1 - 9.1e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SRP54 PF00448.17 KND88930.1 - 0.00063 19.2 0.0 0.0041 16.5 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KND88930.1 - 0.0072 15.7 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND88930.1 - 0.0078 15.9 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KND88930.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 KND88930.1 - 0.033 13.5 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 YhjQ protein MipZ PF09140.6 KND88930.1 - 0.053 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 KND88930.1 - 0.053 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DWNN PF08783.6 KND88931.1 - 5.1e-29 100.0 0.1 9.1e-29 99.2 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KND88931.1 - 0.00024 20.5 4.0 0.00088 18.7 2.8 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.1 KND88931.1 - 0.0057 16.4 2.0 0.011 15.5 1.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 KND88931.1 - 0.0094 15.8 0.1 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.1 KND88931.1 - 0.015 14.9 8.7 0.015 14.9 6.0 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-CCHC PF00098.18 KND88931.1 - 0.027 14.4 1.9 0.054 13.4 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle FYVE_2 PF02318.11 KND88931.1 - 0.12 12.2 5.2 0.063 13.1 2.0 1.7 2 0 0 2 2 1 0 FYVE-type zinc finger zf-RING_4 PF14570.1 KND88931.1 - 0.21 11.2 6.5 0.46 10.1 4.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KND88931.1 - 0.56 9.9 11.0 1.1 9.0 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND88931.1 - 1 9.2 12.4 0.027 14.3 4.2 1.6 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KND88931.1 - 1.6 8.8 15.6 0.1 12.6 6.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND88931.1 - 2.6 7.9 10.0 8.7 6.3 6.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KND88931.1 - 3.5 7.2 9.3 2 7.9 4.9 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF4588 PF15251.1 KND88932.1 - 2.3e-05 24.5 2.8 4.7e-05 23.4 1.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Ion_trans PF00520.26 KND88933.1 - 1.1e-05 24.8 2.6 1.1e-05 24.8 1.8 1.5 2 0 0 2 2 2 1 Ion transport protein Herpes_BLRF2 PF05812.7 KND88933.1 - 0.0097 15.7 0.2 0.042 13.6 0.1 1.8 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 KND88933.1 - 0.041 13.8 0.8 0.076 12.9 0.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor SNF2_N PF00176.18 KND88936.1 - 1e-81 274.0 0.1 1.8e-81 273.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KND88936.1 - 2.2e-44 149.9 4.4 5.5e-44 148.6 3.0 1.8 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KND88936.1 - 5.9e-33 113.6 2.7 5.9e-33 113.6 1.9 3.7 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KND88936.1 - 3.9e-15 55.4 0.0 1.5e-14 53.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND88936.1 - 1.8e-07 31.2 0.0 3.1e-06 27.1 0.0 3.2 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KND88936.1 - 3.1e-07 29.5 0.0 7.9e-07 28.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 KND88936.1 - 8.1e-05 22.1 0.0 0.00022 20.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KND88936.1 - 0.02 14.3 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 CSD PF00313.17 KND88937.1 - 5e-29 99.8 0.6 5.4e-29 99.7 0.4 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KND88937.1 - 0.00068 19.0 0.6 0.00099 18.5 0.4 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.3 KND88937.1 - 0.0077 16.0 0.1 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF WD40 PF00400.27 KND88938.1 - 1.9e-25 87.7 3.4 1.4e-09 37.4 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KND88938.1 - 0.023 13.5 0.0 0.078 11.7 0.0 1.8 1 1 1 2 2 2 0 Coatomer WD associated region Nup160 PF11715.3 KND88938.1 - 0.15 10.1 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 p450 PF00067.17 KND88939.1 - 3.5e-50 170.8 0.0 6.9e-37 127.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 YARHG PF13308.1 KND88939.1 - 0.0061 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 YARHG domain Rho_N PF07498.7 KND88939.1 - 0.0097 15.6 1.0 0.022 14.4 0.7 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain FTHFS PF01268.14 KND88940.1 - 1.8e-253 841.5 0.2 2.4e-253 841.1 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KND88940.1 - 7.5e-68 226.6 0.5 7.5e-68 226.6 0.4 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KND88940.1 - 7.3e-26 90.4 0.5 4.9e-18 65.2 0.0 3.3 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain MFS_1 PF07690.11 KND88941.1 - 1.8e-43 148.5 33.3 3.1e-43 147.8 22.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND88941.1 - 1.5e-06 27.1 14.5 1.5e-06 27.1 10.1 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3405 PF11885.3 KND88942.1 - 1.3e-179 597.6 0.0 1.3e-179 597.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) Tcp11 PF05794.8 KND88942.1 - 0.017 13.8 3.6 0.026 13.2 2.5 1.1 1 0 0 1 1 1 0 T-complex protein 11 FTA4 PF13093.1 KND88942.1 - 0.049 13.0 8.2 0.083 12.3 5.7 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF445 PF04286.7 KND88942.1 - 1.4 8.4 12.3 2.9 7.3 8.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) WASH-7_mid PF14744.1 KND88942.1 - 2.1 7.0 5.3 3.1 6.5 3.7 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 Ycf1 PF05758.7 KND88942.1 - 4.2 4.9 8.1 5.4 4.6 5.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF676 PF05057.9 KND88943.1 - 3.9e-05 23.0 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KND88943.1 - 0.0034 17.1 0.0 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND88943.1 - 0.016 15.1 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KND88943.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein FUSC_2 PF13515.1 KND88945.1 - 5.7e-25 87.7 6.4 5.7e-25 87.7 4.4 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KND88945.1 - 2e-09 36.4 1.4 2e-09 36.4 1.0 2.9 4 0 0 4 4 4 2 Fusaric acid resistance protein family DUF2422 PF10337.4 KND88945.1 - 2.1e-06 26.8 2.4 2.6e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) ALMT PF11744.3 KND88945.1 - 8.3e-05 21.4 9.9 0.055 12.1 4.3 3.8 3 1 0 3 3 3 2 Aluminium activated malate transporter DUF2421 PF10334.4 KND88945.1 - 0.024 14.2 0.1 0.25 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) SPAM PF02090.10 KND88945.1 - 0.12 12.4 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein HAD_2 PF13419.1 KND88946.1 - 7.8e-13 49.0 0.0 9.1e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND88946.1 - 1.1e-07 31.4 0.1 1.8e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KND88946.1 - 1.7e-07 31.8 0.0 0.00056 20.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND88946.1 - 0.0032 17.6 0.0 0.0074 16.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KND88946.1 - 0.011 15.1 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pkinase PF00069.20 KND88947.1 - 2.1e-61 207.3 0.0 2.9e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND88947.1 - 8.6e-39 133.1 0.0 1.1e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND88947.1 - 1.7e-05 23.9 0.0 4e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KND88947.1 - 0.077 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KND88947.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.2 KND88949.1 - 2.2e-79 261.8 9.5 9.7e-26 89.9 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KND88949.1 - 5.3e-72 234.2 0.5 1.9e-08 33.7 0.0 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 KND88949.1 - 1e-66 219.4 7.5 1.6e-10 40.8 0.0 7.6 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88949.1 - 1.3e-60 195.2 1.5 2.7e-06 27.0 0.0 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KND88949.1 - 8.6e-60 198.1 5.2 3.5e-08 33.7 0.1 10.1 2 2 8 10 10 10 10 Ankyrin repeats (many copies) DUF4350 PF14258.1 KND88949.1 - 0.0081 16.3 0.4 20 5.4 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4350) Alpha-amyl_C2 PF07821.7 KND88949.1 - 0.11 12.3 0.3 52 3.8 0.0 3.4 3 0 0 3 3 3 0 Alpha-amylase C-terminal beta-sheet domain DUF2401 PF10287.4 KND88949.1 - 0.15 11.5 0.1 25 4.2 0.0 3.7 4 2 1 6 6 6 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Ank_2 PF12796.2 KND88950.1 - 1.6e-44 150.1 0.0 6.7e-19 68.0 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND88950.1 - 6.5e-42 139.3 0.5 5.7e-07 29.0 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KND88950.1 - 2.7e-36 122.7 5.9 1.2e-07 31.7 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND88950.1 - 5.9e-31 103.4 0.0 0.00047 20.1 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KND88950.1 - 8.2e-31 105.8 0.5 1.6e-08 34.8 0.0 4.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) DUF2675 PF11247.3 KND88950.1 - 0.049 13.6 0.1 3.1 7.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2675) Shigella_OspC PF06128.6 KND88950.1 - 0.15 11.5 0.0 11 5.3 0.0 2.4 3 0 0 3 3 3 0 Shigella flexneri OspC protein FUSC_2 PF13515.1 KND88952.1 - 6.3e-23 81.1 4.5 6.3e-23 81.1 3.1 3.4 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 KND88952.1 - 0.0017 16.8 2.5 0.0017 16.8 1.7 4.3 3 2 1 4 4 4 3 Fusaric acid resistance protein family ALMT PF11744.3 KND88952.1 - 0.0052 15.4 2.4 0.0052 15.4 1.6 3.5 3 0 0 3 3 3 2 Aluminium activated malate transporter NAD_binding_6 PF08030.7 KND88953.1 - 4.9e-21 75.2 0.0 7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KND88953.1 - 1.6e-13 50.8 11.1 2.7e-13 50.1 7.7 1.3 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KND88953.1 - 7.4e-08 32.2 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KND88953.1 - 0.026 15.0 0.0 0.53 10.8 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF515 PF04415.7 KND88953.1 - 0.078 11.1 0.9 0.12 10.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AA_permease_2 PF13520.1 KND88954.1 - 2.5e-53 181.1 46.5 3.2e-53 180.8 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND88954.1 - 1e-21 76.8 34.7 1.4e-21 76.3 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S8 PF00082.17 KND88955.1 - 7.9e-07 28.4 5.1 0.0005 19.3 0.0 2.5 2 1 1 3 3 3 2 Subtilase family DHO_dh PF01180.16 KND88956.1 - 4.6e-21 75.0 0.0 6.1e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 KND88956.1 - 0.4 9.7 3.9 0.61 9.1 2.7 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase MFS_1 PF07690.11 KND88957.1 - 9.7e-08 31.0 32.5 9.7e-08 31.0 22.5 4.2 2 2 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KND88959.1 - 3.6e-22 78.4 0.0 7.8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88959.1 - 4.6e-07 29.6 15.3 7.7e-07 28.9 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 KND88959.1 - 0.081 13.2 0.5 0.21 11.8 0.2 1.7 2 0 0 2 2 2 0 Striatin family Acetyltransf_1 PF00583.19 KND88961.1 - 1.1e-07 31.7 0.1 2.3e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND88961.1 - 2.3e-07 30.8 0.0 2e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND88961.1 - 0.00019 21.2 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND88961.1 - 0.00072 19.6 0.0 0.0029 17.7 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2235 PF09994.4 KND88962.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HpaP PF09483.5 KND88962.1 - 0.96 9.3 12.9 1.1 9.1 8.9 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DEC-1_N PF04625.8 KND88962.1 - 1.4 7.5 13.0 1.7 7.2 9.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2360 PF10152.4 KND88962.1 - 1.7 8.9 7.0 1.9 8.7 4.8 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SR-25 PF10500.4 KND88963.1 - 0.011 15.1 24.6 0.044 13.2 5.7 2.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HAD_2 PF13419.1 KND88964.1 - 8.8e-12 45.5 0.0 6.8e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KND88964.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Fork_head PF00250.13 KND88965.1 - 8.4e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KND88965.1 - 0.00051 20.0 0.1 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain CDK5_activator PF03261.10 KND88965.1 - 1.6 7.9 3.9 5.3 6.2 2.7 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CTP_transf_2 PF01467.21 KND88966.1 - 2.3e-20 73.2 0.0 4.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase PS_Dcarbxylase PF02666.10 KND88967.1 - 1e-48 165.3 0.0 1.5e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KND88967.1 - 8.1e-33 112.1 0.1 1.2e-15 57.0 0.0 2.9 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KND88967.1 - 0.0036 17.4 0.2 0.013 15.6 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KND88967.1 - 0.0037 16.4 0.0 0.0099 15.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KND88967.1 - 0.01 15.6 0.5 0.035 13.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain CEP76-C2 PF15627.1 KND88967.1 - 0.1 12.0 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 CEP76 C2 domain Ribosomal_L19e PF01280.15 KND88968.1 - 1.2e-57 193.8 8.9 2.4e-57 192.8 6.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_2 PF13646.1 KND88968.1 - 1.3e-39 134.3 46.5 9.2e-11 41.8 0.0 13.7 9 3 5 14 14 12 10 HEAT repeats HEAT_EZ PF13513.1 KND88968.1 - 1.1e-36 124.3 55.8 1.2e-06 28.8 0.0 21.9 15 4 9 24 24 23 11 HEAT-like repeat HEAT PF02985.17 KND88968.1 - 5e-36 119.5 31.8 0.0045 16.9 0.0 20.8 23 0 0 23 23 22 9 HEAT repeat Vac14_Fab1_bd PF12755.2 KND88968.1 - 1.5e-15 57.3 0.0 0.13 12.6 0.0 9.4 8 2 2 10 10 10 3 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KND88968.1 - 1.1e-11 45.0 0.4 0.00017 21.5 0.0 5.8 4 1 1 5 5 5 2 Parkin co-regulated protein Cnd1 PF12717.2 KND88968.1 - 1.5e-11 44.4 0.0 0.53 10.1 0.0 8.2 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KND88968.1 - 2.6e-10 40.0 0.0 0.15 11.4 0.0 5.5 4 1 0 5 5 5 3 CLASP N terminal UME PF08064.8 KND88968.1 - 3.6e-09 36.5 0.1 6.2 6.8 0.0 8.1 7 2 4 11 11 11 1 UME (NUC010) domain Ipi1_N PF12333.3 KND88968.1 - 2.4e-06 27.4 0.1 0.0062 16.4 0.1 6.1 6 1 1 7 7 6 1 Rix1 complex component involved in 60S ribosome maturation HEAT_PBS PF03130.11 KND88968.1 - 0.036 14.5 18.5 17 6.2 0.2 9.3 9 0 0 9 9 8 0 PBS lyase HEAT-like repeat Calponin PF00402.13 KND88968.1 - 0.18 11.1 0.1 0.36 10.2 0.1 1.5 1 0 0 1 1 1 0 Calponin family repeat SHMT PF00464.14 KND88969.1 - 5.9e-196 650.5 0.0 6.9e-196 650.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KND88969.1 - 0.019 14.1 0.0 0.052 12.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase FtsJ PF01728.14 KND88971.1 - 5.6e-31 107.9 0.0 7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase B2 PF11473.3 KND88972.1 - 0.0048 16.4 0.3 0.26 10.9 0.0 2.7 2 0 0 2 2 2 1 RNA binding protein B2 CENP-F_leu_zip PF10473.4 KND88972.1 - 0.056 13.2 48.7 0.87 9.4 7.2 3.7 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KND88972.1 - 0.092 11.1 52.0 0.0028 16.1 31.2 1.9 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Filament PF00038.16 KND88972.1 - 0.24 10.8 39.1 2.1 7.7 10.9 3.4 1 1 2 3 3 3 0 Intermediate filament protein ADIP PF11559.3 KND88972.1 - 2.1 8.2 45.2 1.1 9.1 8.5 3.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KND88972.1 - 2.3 7.3 8.8 7 5.7 1.9 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 KND88972.1 - 2.7 7.5 45.0 38 3.8 15.3 2.8 1 1 1 2 2 2 0 IncA protein CFEM PF05730.6 KND88973.1 - 1.7e-07 30.9 11.3 3.5e-07 29.9 7.9 1.5 1 0 0 1 1 1 1 CFEM domain Mid2 PF04478.7 KND88973.1 - 0.0013 18.1 0.1 0.0013 18.1 0.1 1.7 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Rax2 PF12768.2 KND88973.1 - 0.042 13.0 0.3 0.062 12.5 0.2 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Lamp PF01299.12 KND88973.1 - 0.32 10.1 0.0 0.32 10.1 0.0 3.1 2 1 1 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) WD40 PF00400.27 KND88974.1 - 1.5e-60 199.0 24.2 4.5e-11 42.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KND88974.1 - 3.3e-06 25.5 7.3 0.061 11.4 0.2 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 OST3_OST6 PF04756.8 KND88975.1 - 2.3e-19 69.5 0.8 3.2e-19 69.0 0.5 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Abi PF02517.11 KND88975.1 - 2.2 8.4 6.3 10 6.3 4.4 2.0 1 1 0 1 1 1 0 CAAX protease self-immunity 2OG-FeII_Oxy_2 PF13532.1 KND88976.1 - 6.4e-25 88.1 0.0 9.6e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 KND88976.1 - 7.7e-24 84.5 0.0 2.7e-23 82.7 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.1 KND88976.1 - 8.5e-06 25.5 1.2 2.9e-05 23.8 0.9 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND88976.1 - 3.8e-05 24.0 0.0 9.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAF8_C PF10406.4 KND88977.1 - 6e-12 45.4 0.2 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KND88977.1 - 6.8e-11 41.7 0.1 3.5e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated FAD_binding_4 PF01565.18 KND88978.1 - 1.2e-12 47.4 1.6 3.2e-12 46.0 1.1 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND88978.1 - 4.3e-09 36.1 0.0 8.8e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like SPT16 PF08644.6 KND88979.1 - 2.3e-51 173.6 0.2 2.3e-51 173.6 0.1 3.2 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KND88979.1 - 1.6e-49 167.5 0.1 5.8e-49 165.7 0.1 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KND88979.1 - 2.1e-22 79.7 0.0 4.3e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KND88979.1 - 5e-22 77.6 0.1 1.3e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CDC50 PF03381.10 KND88980.1 - 8.2e-102 340.0 0.1 1e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Transthyretin PF00576.16 KND88982.1 - 1.5e-26 92.4 1.4 1.5e-15 57.0 0.2 2.1 1 1 1 2 2 2 2 HIUase/Transthyretin family Methyltransf_21 PF05050.7 KND88982.1 - 0.085 12.7 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase FkbM domain CarboxypepD_reg PF13620.1 KND88982.1 - 0.089 12.8 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.13 KND88984.1 - 1.7e-05 24.6 8.4 3e-05 23.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_1 PF00013.24 KND88985.1 - 2e-08 33.7 0.1 4.1e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KND88985.1 - 1.8e-05 24.2 0.1 3.8e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 KH domain Peptidase_M28 PF04389.12 KND88986.1 - 1.2e-33 116.3 0.1 2.7e-33 115.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KND88986.1 - 0.0057 16.1 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KND88986.1 - 0.23 10.2 0.0 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF2305 PF10230.4 KND88987.1 - 2.7e-43 148.3 0.0 3.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KND88987.1 - 0.0017 18.3 3.0 0.0022 17.9 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND88987.1 - 0.01 15.5 0.1 0.015 15.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 KND88988.1 - 8.7e-07 28.0 0.5 3.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND88988.1 - 1e-06 28.5 11.4 2.1e-06 27.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fmp27 PF10344.4 KND88989.1 - 2.1e-223 743.7 0.0 4.3e-223 742.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KND88989.1 - 5e-163 543.1 0.0 5e-163 543.1 0.0 2.3 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KND88989.1 - 3.6e-151 503.8 1.8 7.1e-151 502.8 0.0 2.3 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KND88989.1 - 8.1e-52 175.1 0.3 2.1e-51 173.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KND88989.1 - 3.1e-51 173.3 0.0 7.3e-51 172.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KND88989.1 - 8.2e-35 119.3 0.0 4.3e-34 117.0 0.0 2.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.8 KND88989.1 - 0.0071 16.0 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Ribosomal_S19e PF01090.14 KND88990.1 - 1e-54 183.7 0.1 1.2e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF4449 PF14613.1 KND88991.1 - 1.5e-61 207.1 0.8 1.5e-61 207.1 0.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Med23 PF11573.3 KND88991.1 - 0.16 9.2 0.2 0.23 8.7 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 DUF3818 PF12825.2 KND88992.1 - 1.6e-32 112.5 0.0 2.4e-27 95.5 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KND88992.1 - 2.1e-28 98.6 0.0 6.2e-28 97.1 0.0 1.7 1 1 0 1 1 1 1 PX-associated TrkA_N PF02254.13 KND88992.1 - 0.037 14.0 3.3 0.44 10.5 0.2 2.4 2 0 0 2 2 2 0 TrkA-N domain CorA PF01544.13 KND88993.1 - 0.15 11.0 4.5 0.33 9.9 3.1 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Amidase PF01425.16 KND88994.1 - 7.5e-53 179.9 0.1 1.4e-51 175.8 0.1 2.1 1 1 1 2 2 2 2 Amidase MFS_1 PF07690.11 KND88995.1 - 1.2e-19 70.2 31.6 1.2e-19 70.2 21.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily CENP-B_N PF04218.8 KND88995.1 - 0.019 14.3 0.2 0.04 13.3 0.1 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain UL73_N PF12522.3 KND88996.1 - 0.87 9.1 9.9 2.1 7.9 6.8 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Zn_clus PF00172.13 KND88997.1 - 1.7e-06 27.7 7.3 3.4e-06 26.8 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ham1p_like PF01725.11 KND88998.1 - 9.5e-41 139.2 0.0 2.7e-38 131.2 0.0 2.0 1 1 1 2 2 2 2 Ham1 family Peptidase_M16_C PF05193.16 KND89000.1 - 9.5e-51 172.0 0.0 4.8e-50 169.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND89000.1 - 4.3e-41 140.1 0.0 1.6e-38 131.7 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) S1 PF00575.18 KND89002.1 - 4.7e-80 263.6 41.2 4.3e-14 52.3 0.3 13.2 13 1 0 13 13 13 11 S1 RNA binding domain TPR_14 PF13428.1 KND89002.1 - 0.00011 22.4 0.3 0.33 11.7 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 KND89002.1 - 0.00056 19.7 9.5 0.011 15.5 0.0 3.2 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) PilZ PF07238.9 KND89002.1 - 0.0028 17.6 0.2 0.23 11.4 0.0 3.9 3 0 0 3 3 3 1 PilZ domain TPR_19 PF14559.1 KND89002.1 - 0.0085 16.4 0.5 6.6 7.1 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Fungal_trans PF04082.13 KND89003.1 - 2.7e-17 62.5 0.0 7.5e-17 61.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89003.1 - 1e-14 54.1 27.5 1.3e-07 31.3 7.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.21 KND89004.1 - 7.7e-19 67.4 0.1 1.1e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase PF01425.16 KND89005.1 - 1e-30 106.9 0.3 2.2e-30 105.8 0.2 1.5 2 0 0 2 2 2 1 Amidase AMP-binding PF00501.23 KND89006.1 - 6.2e-70 235.6 0.0 7.3e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND89006.1 - 2.1e-10 41.3 0.9 7.8e-10 39.5 0.4 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Med18 PF09637.5 KND89012.1 - 4.5e-25 88.6 0.0 5.4e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Hyd_WA PF06462.7 KND89013.1 - 0.47 10.1 2.5 7.2 6.3 1.6 2.6 2 1 0 2 2 2 0 Propeller adh_short PF00106.20 KND89015.1 - 6e-14 52.3 0.0 7.9e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KND89015.1 - 3.8e-06 26.8 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND89015.1 - 0.0034 17.0 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KND89015.1 - 0.027 13.9 0.0 0.32 10.3 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Epimerase PF01370.16 KND89016.1 - 1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND89016.1 - 1.6e-09 37.0 0.0 3.2e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KND89016.1 - 0.00044 20.2 0.2 0.0016 18.4 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Gly_transf_sug PF04488.10 KND89017.1 - 2.4e-08 34.2 0.0 5.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KND89017.1 - 0.0021 16.6 0.4 0.0041 15.6 0.1 1.4 1 1 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain LDB19 PF13002.2 KND89018.1 - 1.9e-37 128.6 0.5 4.5e-37 127.4 0.1 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 KND89018.1 - 9.3e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Corona_nucleoca PF00937.13 KND89018.1 - 5.6 5.8 6.4 9.1 5.1 4.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DIOX_N PF14226.1 KND89019.1 - 5.5e-18 65.6 0.0 1.1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND89019.1 - 1.4e-10 41.3 0.0 2.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KND89020.1 - 1.6e-27 96.3 0.0 3.1e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND89020.1 - 1.1e-15 57.6 0.0 2.9e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 KND89021.1 - 1.3e-10 41.5 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89021.1 - 7.7e-09 35.4 0.0 7.4e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KND89021.1 - 4.9e-07 29.2 0.0 1.7e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KND89021.1 - 0.00031 20.0 0.0 0.0091 15.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KND89021.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KND89021.1 - 0.0021 16.6 0.1 0.0083 14.6 0.0 1.8 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) APH PF01636.18 KND89022.1 - 8.9e-11 41.9 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND89022.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase NAAA-beta PF15508.1 KND89022.1 - 0.031 14.6 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4470 PF14737.1 KND89023.1 - 2e-13 49.9 0.1 3.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KND89023.1 - 1.3e-07 31.3 6.4 2.8e-07 30.3 4.5 1.5 1 0 0 1 1 1 1 MYND finger Rhodanese PF00581.15 KND89024.1 - 1.9e-06 28.2 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain FMN_red PF03358.10 KND89025.1 - 2.5e-24 85.5 0.0 3.6e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KND89025.1 - 0.0099 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold DNA_ligase_A_M PF01068.16 KND89026.1 - 7.4e-43 146.2 0.0 1.4e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KND89026.1 - 1.4e-36 126.0 0.0 3e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KND89026.1 - 1.6e-15 57.2 0.0 1.1e-14 54.5 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KND89026.1 - 3.4e-09 36.7 0.0 7.9e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KND89026.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.2 KND89026.1 - 0.012 15.4 0.2 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain mRNA_cap_enzyme PF01331.14 KND89026.1 - 0.024 14.3 0.1 0.77 9.4 0.0 2.5 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Adenylsucc_synt PF00709.16 KND89027.1 - 2e-156 520.8 0.0 2.3e-156 520.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CRCB PF02537.10 KND89028.1 - 4.5e-31 107.1 22.6 1.8e-19 69.7 6.8 3.4 3 0 0 3 3 3 3 CrcB-like protein UPRTase PF14681.1 KND89029.1 - 1.1e-71 240.3 0.0 1.2e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KND89029.1 - 5e-08 32.7 0.1 1.2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 KND89029.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain TMP-TENI PF02581.12 KND89029.1 - 0.16 11.1 0.4 0.8 8.7 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Amidoligase_2 PF12224.3 KND89030.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative amidoligase enzyme DJ-1_PfpI PF01965.19 KND89031.1 - 4.4e-09 35.9 0.0 8.5e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KND89031.1 - 9.2e-05 21.7 0.0 0.00016 21.0 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase SNO PF01174.14 KND89031.1 - 0.054 13.1 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Fungal_trans_2 PF11951.3 KND89032.1 - 5.8e-20 71.2 0.0 3.8e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89032.1 - 3.4e-08 33.2 5.3 7.5e-08 32.1 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.10 KND89033.1 - 4.9e-05 21.9 0.1 5.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.2 KND89033.1 - 0.056 13.1 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 F-box-like OPT PF03169.10 KND89034.1 - 3.8e-10 38.8 0.0 5.1e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 KND89035.1 - 0.0038 15.7 0.1 0.0039 15.6 0.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_transf_20 PF00982.16 KND89036.1 - 1.1e-150 502.2 0.0 1.6e-150 501.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KND89036.1 - 1e-75 253.6 0.0 2.1e-75 252.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Sugar_tr PF00083.19 KND89037.1 - 6.2e-126 420.6 29.9 7.1e-126 420.3 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND89037.1 - 1.5e-20 73.2 44.8 8e-14 51.1 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 KND89039.1 - 5.8e-157 522.6 0.0 7.8e-157 522.2 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KND89039.1 - 2.1e-20 72.6 0.1 3.5e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KND89039.1 - 1.6e-08 34.4 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Herpes_alk_exo PF01771.12 KND89040.1 - 0.035 12.5 0.1 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease CFEM PF05730.6 KND89041.1 - 2e-13 49.9 12.9 3.1e-13 49.3 8.9 1.3 1 0 0 1 1 1 1 CFEM domain TctB PF07331.6 KND89041.1 - 0.32 10.6 7.0 12 5.5 4.9 2.3 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Pyr_redox_2 PF07992.9 KND89042.1 - 1e-30 107.1 0.2 1.3e-30 106.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND89042.1 - 9.1e-20 70.8 0.7 2.4e-17 63.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KND89042.1 - 2e-19 69.6 0.0 8e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 KND89042.1 - 0.00012 22.2 0.1 0.00055 20.0 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KND89042.1 - 0.0059 15.5 4.2 0.013 14.3 1.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KND89042.1 - 0.0063 16.1 1.0 1.4 8.5 0.0 2.5 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 KND89042.1 - 0.0066 15.4 0.1 0.064 12.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KND89042.1 - 0.0097 15.4 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KND89042.1 - 0.012 15.0 0.5 0.32 10.3 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 KND89042.1 - 0.95 9.5 4.8 12 5.9 0.5 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TMEM154 PF15102.1 KND89043.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Acyl_transf_1 PF00698.16 KND89044.1 - 2.7e-15 56.5 0.3 4.5e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KND89044.1 - 6.4e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KND89044.1 - 0.0062 16.4 3.1 0.017 14.9 2.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KND89044.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1049 PF06305.6 KND89045.1 - 0.023 14.1 1.2 0.023 14.1 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) FBPase_glpX PF03320.8 KND89045.1 - 0.057 12.0 0.1 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded NifZ PF04319.8 KND89047.1 - 0.084 12.2 0.2 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 NifZ domain PLAC8 PF04749.12 KND89049.1 - 9.7e-25 87.1 10.8 9.7e-25 87.1 7.5 1.4 2 0 0 2 2 2 1 PLAC8 family ACT_3 PF10000.4 KND89050.1 - 9e-12 44.5 0.1 3.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 ACT domain HTH_28 PF13518.1 KND89050.1 - 4.2e-08 33.0 0.3 8.3e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 KND89050.1 - 2.1e-07 31.0 0.3 5e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KND89050.1 - 4.6e-07 29.2 0.2 1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain ACT_7 PF13840.1 KND89050.1 - 0.00077 18.9 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain MarR_2 PF12802.2 KND89050.1 - 0.00086 18.9 0.3 0.0025 17.4 0.1 1.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 KND89050.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.14 KND89050.1 - 0.02 14.8 0.0 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_32 PF13565.1 KND89050.1 - 0.032 15.0 1.3 0.083 13.6 0.3 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 KND89050.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_Tnp_ISL3 PF13542.1 KND89050.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 LZ_Tnp_IS481 PF13011.1 KND89050.1 - 0.25 11.7 1.5 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_1 PF00126.22 KND89050.1 - 2.4 7.9 6.2 2.4 7.9 0.1 2.8 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family JAB PF01398.16 KND89052.1 - 4.3e-30 103.7 0.1 1.3e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KND89052.1 - 6.7e-08 32.0 0.0 1.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3722 PF12519.3 KND89053.1 - 1.5e-81 273.4 0.0 1.9e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KND89053.1 - 0.00075 18.8 0.1 0.069 12.4 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic porin Zip PF02535.17 KND89054.1 - 6.9e-56 189.5 1.3 1.1e-55 188.8 0.9 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter PsbL PF02419.12 KND89054.1 - 0.042 13.2 0.0 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 PsbL protein STOP PF05217.7 KND89055.1 - 0.016 14.9 0.5 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 STOP protein YbfN PF13982.1 KND89056.1 - 0.06 13.5 1.8 0.083 13.0 0.0 2.0 1 1 1 2 2 2 0 YbfN-like lipoprotein HTH_27 PF13463.1 KND89058.1 - 0.034 14.4 0.0 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain Vps16_N PF04841.8 KND89060.1 - 3.6e-86 289.2 0.0 6.9e-86 288.3 0.0 1.4 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 KND89060.1 - 4.1e-67 226.3 0.0 6.1e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ATG16 PF08614.6 KND89061.1 - 3.1e-41 141.3 17.4 4.7e-41 140.7 12.0 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) SCP-1 PF05483.7 KND89061.1 - 0.00018 19.4 2.2 0.00025 19.0 1.5 1.2 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) APG6 PF04111.7 KND89061.1 - 0.027 13.5 13.2 0.11 11.5 8.4 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 YlqD PF11068.3 KND89061.1 - 0.11 12.5 8.7 0.38 10.7 3.6 2.3 1 1 0 2 2 2 0 YlqD protein SlyX PF04102.7 KND89061.1 - 0.16 12.3 9.2 2.4 8.6 1.8 3.3 2 1 1 3 3 3 0 SlyX TBPIP PF07106.8 KND89061.1 - 0.2 11.1 10.3 0.55 9.7 4.1 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) KLRAQ PF10205.4 KND89061.1 - 0.23 11.5 12.3 0.3 11.1 6.4 2.5 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.4 KND89061.1 - 0.41 9.5 8.9 1.1 8.1 6.2 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 KND89061.1 - 0.62 9.1 3.0 3.1 6.8 1.9 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 KND89061.1 - 1.2 8.6 14.3 5.3 6.5 4.1 2.9 1 1 2 3 3 3 0 IncA protein Cep57_CLD_2 PF14197.1 KND89061.1 - 3.8 7.5 17.1 30 4.6 4.7 3.6 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 Cluap1 PF10234.4 KND89061.1 - 6.2 5.9 11.6 11 5.1 4.9 2.3 2 1 0 2 2 2 0 Clusterin-associated protein-1 CENP-H PF05837.7 KND89061.1 - 8.3 6.6 12.3 1.1 9.4 0.7 3.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Oxidored_q6 PF01058.17 KND89062.1 - 6.6e-23 80.7 0.1 9.3e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit FA_desaturase PF00487.19 KND89066.1 - 6.6e-39 133.8 20.3 1e-38 133.3 14.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Fungal_trans PF04082.13 KND89067.1 - 4.2e-12 45.4 0.2 7e-12 44.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89067.1 - 1.9e-05 24.5 7.0 1.9e-05 24.5 4.8 3.1 3 1 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KND89067.1 - 5.6e-05 23.2 13.7 0.00098 19.3 0.9 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type PyrI_C PF02748.10 KND89067.1 - 0.068 12.6 3.3 0.21 11.0 2.0 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_2 PF13465.1 KND89067.1 - 0.075 13.3 8.6 0.068 13.4 2.0 3.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KND89067.1 - 0.77 9.9 8.7 3.6 7.8 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KND89067.1 - 2.4 8.6 27.9 0.054 13.8 1.0 4.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-BED PF02892.10 KND89067.1 - 9.9 6.0 14.4 3.6 7.4 1.3 2.9 2 1 1 3 3 3 0 BED zinc finger PNK3P PF08645.6 KND89068.1 - 3.9e-53 179.1 0.0 5.8e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KND89068.1 - 4.3e-32 110.9 0.0 1.9e-31 108.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND89068.1 - 0.00014 21.0 0.0 0.0005 19.2 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KND89068.1 - 0.0079 17.0 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND89068.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 KND89068.1 - 0.022 14.9 0.0 5.1 7.2 0.0 3.1 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase AAA_29 PF13555.1 KND89068.1 - 0.028 13.9 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 KND89068.1 - 0.069 12.8 0.0 2 8.0 0.0 2.4 1 1 1 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.10 KND89068.1 - 0.075 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KTI12 PF08433.5 KND89068.1 - 0.084 12.0 0.3 8.7 5.4 0.1 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Sugar_tr PF00083.19 KND89069.1 - 5.8e-75 252.5 20.8 7.4e-75 252.2 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND89069.1 - 3.5e-13 48.9 63.7 2.6e-11 42.8 25.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KND89070.1 - 3.3e-59 200.6 0.0 4.9e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KND89071.1 - 2.5e-20 72.8 0.0 3.9e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89071.1 - 2.1e-08 34.5 0.0 9.7e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89071.1 - 2.7e-08 34.3 0.0 2.6e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND89071.1 - 4.5e-08 33.4 0.0 1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89071.1 - 9.9e-06 25.8 0.0 2.6e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89071.1 - 2.5e-05 23.9 0.0 0.00022 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND89071.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KND89071.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KND89071.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KND89071.1 - 0.021 14.8 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KND89071.1 - 0.033 13.3 0.0 0.18 10.9 0.0 2.1 2 1 0 2 2 2 0 O-methyltransferase CMAS PF02353.15 KND89071.1 - 0.041 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KND89071.1 - 0.055 12.9 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KND89071.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KND89071.1 - 0.065 12.3 0.0 2.3 7.2 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Fungal_trans PF04082.13 KND89072.1 - 3.8e-15 55.4 0.1 5.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEP PF00610.16 KND89072.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.11 KND89073.1 - 5.1e-20 71.4 21.3 7.4e-12 44.6 9.5 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Zn_clus PF00172.13 KND89074.1 - 1.5e-08 34.3 10.1 2.4e-08 33.7 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND89074.1 - 4.2e-05 22.5 0.1 7.3e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRP14 PF15459.1 KND89074.1 - 0.056 13.5 0.2 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 zf-C2H2_4 PF13894.1 KND89075.1 - 5.6e-06 26.3 12.6 0.00093 19.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND89075.1 - 6.3e-06 26.2 4.0 6.3e-06 26.2 2.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KND89075.1 - 2.7e-05 24.2 11.5 0.0096 16.2 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KND89075.1 - 0.1 12.5 0.8 0.35 10.8 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2434 PF10361.4 KND89076.1 - 6.2e-111 370.2 9.9 7.9e-111 369.8 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.4 KND89077.1 - 3.2e-37 127.4 0.5 3.2e-37 127.4 0.4 2.7 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Gelsolin PF00626.17 KND89077.1 - 1.7e-29 101.2 0.0 2.7e-10 39.7 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat Rabaptin PF03528.10 KND89077.1 - 0.059 13.2 0.6 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 Rabaptin RRM_1 PF00076.17 KND89079.1 - 3.4e-13 49.0 0.0 5.8e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND89079.1 - 3.9e-11 42.7 0.0 6.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND89079.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAGA_bind PF06217.7 KND89079.1 - 5.7 6.8 11.7 15 5.4 8.1 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 KND89079.1 - 8.1 5.7 20.8 14 5.0 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ABA_GPCR PF12430.3 KND89080.1 - 8.9e-43 145.7 0.0 1.7e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KND89080.1 - 2.6e-18 65.8 0.1 2e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) SpoV PF08183.6 KND89080.1 - 0.045 13.4 0.8 0.11 12.2 0.6 1.7 1 0 0 1 1 1 0 Stage V sporulation protein family Usp PF00582.21 KND89081.1 - 2e-12 47.4 5.1 1e-11 45.2 0.0 3.6 3 0 0 3 3 3 1 Universal stress protein family Paf67 PF10255.4 KND89082.1 - 3.5e-153 510.2 1.0 4.2e-153 510.0 0.7 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KND89082.1 - 0.039 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 KND89084.1 - 1.7e-54 184.1 0.0 3.5e-54 183.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KND89084.1 - 7.3e-16 57.8 0.0 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND89084.1 - 6.9e-08 32.4 0.0 2.1e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KND89084.1 - 9.5e-08 31.7 0.0 2.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KND89084.1 - 0.00068 19.1 0.0 0.027 14.0 0.0 2.7 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KND89084.1 - 0.0039 17.1 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Amidohydro_3 PF07969.6 KND89085.1 - 7.9e-54 183.4 0.7 9.9e-54 183.0 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND89085.1 - 2.1e-10 40.2 0.1 6.5e-10 38.6 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KND89085.1 - 3.5e-05 23.6 0.2 0.00045 19.9 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KND89085.1 - 0.0062 16.6 0.1 0.0062 16.6 0.0 3.0 2 1 0 2 2 2 1 Amidohydrolase FMN_bind_2 PF04299.7 KND89086.1 - 1.3e-45 154.9 0.0 1.6e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.3 KND89087.1 - 1.1e-41 142.7 0.0 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89087.1 - 2.2e-07 30.6 7.3 2.2e-07 30.6 5.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KND89089.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acyl-CoA_dh_2 PF08028.6 KND89090.1 - 5e-19 68.8 0.5 7.5e-19 68.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KND89090.1 - 0.00026 21.1 0.1 0.00069 19.7 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND89090.1 - 0.00078 20.0 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2190 PF09956.4 KND89090.1 - 0.016 14.9 0.3 0.063 13.0 0.2 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) OPT PF03169.10 KND89091.1 - 2.3e-143 478.9 47.8 2.6e-143 478.7 33.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CTF_NFI PF00859.13 KND89092.1 - 0.00018 21.3 3.4 0.00027 20.7 2.4 1.2 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region SSP160 PF06933.6 KND89092.1 - 0.98 7.3 6.5 1.4 6.8 4.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Amidohydro_5 PF13594.1 KND89093.1 - 1.1e-07 31.4 0.1 3.2e-06 26.8 0.0 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KND89093.1 - 9.5e-07 29.1 4.2 9.4e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KND89093.1 - 4.3e-05 23.3 0.5 0.00033 20.4 0.0 2.7 3 1 0 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.6 KND89093.1 - 0.0031 16.7 0.8 0.01 15.0 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase family LigB PF02900.13 KND89094.1 - 9.7e-33 113.3 0.0 1.2e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GST_C_3 PF14497.1 KND89095.1 - 4e-10 40.0 0.0 5.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KND89095.1 - 4e-06 26.9 0.0 1.1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KND89095.1 - 6.2e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KND89095.1 - 7.5e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAD_binding_2 PF03446.10 KND89096.1 - 5.9e-24 84.7 0.0 1.2e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KND89096.1 - 1.4e-06 28.5 0.2 5.4e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KND89096.1 - 2e-05 23.7 0.0 4.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KND89096.1 - 6.6e-05 22.3 0.1 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 KND89096.1 - 7.6e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 KND89096.1 - 0.00015 21.7 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Saccharop_dh PF03435.13 KND89096.1 - 0.028 13.4 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 KND89096.1 - 0.028 14.9 0.1 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.9 KND89096.1 - 0.041 13.2 1.0 4.2 6.7 0.7 2.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KND89096.1 - 0.12 12.1 0.3 0.47 10.1 0.2 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SBF PF01758.11 KND89097.1 - 5.6e-50 169.3 10.7 5.6e-50 169.3 7.4 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Methyltransf_31 PF13847.1 KND89098.1 - 3.4e-27 94.9 0.0 4.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND89098.1 - 5.9e-16 58.2 0.1 8.7e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KND89098.1 - 9e-16 58.1 0.1 1.9e-15 57.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89098.1 - 6.3e-12 45.7 0.2 1.4e-11 44.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89098.1 - 1.1e-10 42.0 0.1 1.8e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND89098.1 - 7.7e-10 38.7 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89098.1 - 1.5e-09 38.1 0.0 2.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND89098.1 - 4.7e-07 29.8 0.0 9.7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND89098.1 - 2.4e-05 23.9 0.0 4.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KND89098.1 - 6e-05 22.2 0.1 9e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KND89098.1 - 0.00025 20.7 0.0 0.00037 20.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND89098.1 - 0.00055 19.3 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KND89098.1 - 0.0044 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.12 KND89098.1 - 0.0064 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin FtsJ PF01728.14 KND89098.1 - 0.0079 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N PF00107.21 KND89098.1 - 0.019 14.5 0.1 0.22 11.0 0.1 2.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DOT1 PF08123.8 KND89098.1 - 0.085 12.1 0.2 0.18 11.1 0.1 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 KND89098.1 - 0.14 11.2 0.0 0.31 10.0 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_19 PF04672.7 KND89098.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.6 1 1 0 1 1 1 0 S-adenosyl methyltransferase Abhydrolase_4 PF08386.5 KND89100.1 - 1.7e-19 69.5 0.0 5e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KND89100.1 - 5.8e-15 55.4 0.1 5.6e-06 26.0 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND89100.1 - 2.2e-08 34.2 12.8 3.1e-05 23.9 8.9 3.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89100.1 - 0.00016 21.4 0.3 0.004 16.8 0.2 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ricin_B_lectin PF00652.17 KND89101.1 - 1.6e-08 34.6 0.0 3.7e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain GFA PF04828.9 KND89103.1 - 2.8e-13 49.6 0.5 4.8e-13 48.8 0.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme EI24 PF07264.6 KND89104.1 - 0.00017 21.0 3.2 0.00017 21.0 2.2 2.1 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) ketoacyl-synt PF00109.21 KND89106.1 - 1.6e-84 283.3 0.0 2.8e-84 282.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND89106.1 - 1.8e-45 155.6 0.0 9.9e-45 153.2 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KND89106.1 - 1.5e-34 118.3 0.2 5e-34 116.6 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KND89106.1 - 1.4e-20 73.6 0.0 2.6e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 KND89106.1 - 4.1e-20 72.9 0.0 8.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KND89106.1 - 1.5e-12 47.5 0.7 8.7e-05 22.7 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KND89106.1 - 2.2e-08 34.2 0.0 5.2e-07 29.7 0.0 3.1 4 0 0 4 4 4 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KND89106.1 - 3.9e-05 22.7 0.0 0.00047 19.2 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KND89106.1 - 0.0015 18.2 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family AMP-binding PF00501.23 KND89107.1 - 3.2e-34 118.0 0.1 1.6e-33 115.6 0.0 2.1 2 1 1 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KND89107.1 - 1.2e-20 73.5 0.0 1.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KND89107.1 - 1.8e-05 24.2 0.0 0.00014 21.3 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KND89107.1 - 3.8e-05 23.8 0.0 0.00019 21.6 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 KND89107.1 - 0.00062 19.7 0.8 0.013 15.4 0.1 3.1 3 1 1 4 4 4 1 short chain dehydrogenase KR PF08659.5 KND89107.1 - 0.014 15.0 0.0 0.038 13.6 0.0 1.8 1 0 0 1 1 1 0 KR domain Abhydrolase_3 PF07859.8 KND89108.1 - 1.6e-18 67.0 0.0 4.1e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND89108.1 - 6.6e-05 22.8 0.0 9.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89108.1 - 0.0018 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND89108.1 - 0.0097 15.4 0.0 0.0097 15.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 KND89109.1 - 1.6e-29 103.0 0.0 6.2e-29 101.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KND89109.1 - 7.7e-09 35.1 0.0 0.0003 19.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND89109.1 - 2.3e-07 30.7 0.1 2.7e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND89109.1 - 9e-07 28.1 1.2 2.4e-05 23.4 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND89109.1 - 4.4e-05 22.5 1.6 4.6e-05 22.4 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KND89109.1 - 8.1e-05 22.9 0.4 0.034 14.5 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KND89109.1 - 0.00077 19.0 0.1 0.0017 17.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KND89109.1 - 0.0011 18.0 0.1 0.0028 16.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KND89109.1 - 0.0023 17.7 0.6 1.3 8.7 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND89109.1 - 0.0025 17.9 0.1 0.0048 16.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND89109.1 - 0.0026 17.6 0.3 0.0053 16.6 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND89109.1 - 0.006 15.2 0.1 0.013 14.2 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 KND89109.1 - 0.0075 16.2 0.4 0.042 13.8 0.0 2.4 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 KND89109.1 - 0.011 14.6 0.2 2.6 6.8 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KND89109.1 - 0.02 14.9 0.4 0.039 14.0 0.3 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KND89109.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Myb_DNA-binding PF00249.26 KND89110.1 - 8.9e-30 102.4 5.5 1.8e-11 43.9 0.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND89110.1 - 6.6e-24 83.7 10.4 1.3e-13 50.8 0.1 3.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KND89110.1 - 1.9 8.7 4.3 13 6.0 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.11 KND89111.1 - 1.9e-29 102.5 58.3 1.1e-28 99.9 37.7 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KND89112.1 - 9.1e-54 182.8 0.0 2e-53 181.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KND89112.1 - 6.9e-05 22.5 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KND89112.1 - 0.00014 22.1 0.0 0.0012 19.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND89112.1 - 0.00074 18.6 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KND89112.1 - 0.0012 17.7 0.2 0.084 11.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KND89112.1 - 0.0044 15.9 0.3 0.0079 15.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KND89112.1 - 0.0052 16.7 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND89112.1 - 0.018 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND89112.1 - 0.039 12.4 0.1 0.059 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KND89112.1 - 0.054 12.3 0.1 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KND89112.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 KND89112.1 - 0.096 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KND89112.1 - 0.24 10.2 0.2 0.36 9.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_2 PF00891.13 KND89113.1 - 1.3e-25 89.9 0.0 1.2e-21 77.0 0.0 3.0 3 0 0 3 3 3 2 O-methyltransferase Methyltransf_18 PF12847.2 KND89113.1 - 0.12 12.9 0.1 3.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain AA_permease_2 PF13520.1 KND89114.1 - 4.3e-79 266.0 38.6 4.3e-79 266.0 26.8 1.5 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 KND89114.1 - 7.1e-13 47.7 41.8 2e-12 46.2 29.0 1.6 1 1 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.15 KND89115.1 - 8.1e-44 149.3 1.8 9.8e-43 145.8 1.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KND89115.1 - 3.3e-20 73.4 0.0 2.1e-19 70.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND89115.1 - 2.5e-16 60.3 0.3 7.3e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND89115.1 - 3.7e-12 45.5 0.0 9e-12 44.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KND89115.1 - 3.1e-07 30.2 0.0 6.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 KND89115.1 - 6.8e-06 25.7 2.4 4.4e-05 23.0 0.2 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus HAD_2 PF13419.1 KND89115.1 - 0.047 13.9 0.0 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Gln-synt_C PF00120.19 KND89116.1 - 1.2e-53 181.8 0.0 1.6e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain PSD2 PF07624.6 KND89116.1 - 0.053 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Fumerase PF05681.9 KND89116.1 - 0.071 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Methyltransf_23 PF13489.1 KND89117.1 - 1.3e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C65 PF10275.4 KND89118.1 - 1.2e-61 208.1 0.0 1.5e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain MFS_1 PF07690.11 KND89119.1 - 1.1e-20 73.6 35.1 1.1e-20 73.6 24.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily PCI PF01399.22 KND89119.1 - 7.3e-15 55.1 0.0 1.7e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KND89119.1 - 1.5e-06 27.9 0.3 8.3e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 MFS_2 PF13347.1 KND89119.1 - 4.7e-05 21.9 23.7 5.6e-05 21.7 5.6 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1180 PF06679.7 KND89120.1 - 0.22 11.4 0.8 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) NUDIX PF00293.23 KND89121.1 - 5.7e-07 29.2 0.0 9.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ICAT PF06384.6 KND89122.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Fra10Ac1 PF09725.4 KND89122.1 - 0.86 9.7 3.5 4.8 7.2 0.9 2.3 1 1 1 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 RRM_1 PF00076.17 KND89123.1 - 4.4e-07 29.4 0.0 1.7e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND89123.1 - 0.00041 20.2 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND89123.1 - 0.023 14.5 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMO PF03060.10 KND89127.1 - 5.8e-36 124.2 6.4 6.3e-28 97.8 2.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KND89127.1 - 2.6e-08 33.1 0.8 3.9e-05 22.6 0.9 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KND89127.1 - 3.7e-05 22.7 4.9 6e-05 22.0 3.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KND89127.1 - 0.0007 18.6 0.2 0.0012 17.7 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NmrA PF05368.8 KND89128.1 - 8.4e-38 129.9 0.0 1.1e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND89128.1 - 5.6e-10 39.5 0.0 7.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND89128.1 - 1.3e-06 27.3 0.0 1.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KND89128.1 - 0.0001 22.2 0.1 0.00024 21.1 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KND89128.1 - 0.00027 20.6 0.2 0.00043 19.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND89128.1 - 0.00042 19.8 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KND89128.1 - 0.00092 19.1 0.2 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.16 KND89128.1 - 0.082 12.4 0.3 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 KND89128.1 - 0.087 13.2 0.4 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2235 PF09994.4 KND89129.1 - 2e-64 217.6 0.0 2.8e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DoxX_2 PF13564.1 KND89129.1 - 0.17 11.8 0.3 0.56 10.2 0.0 1.8 2 0 0 2 2 2 0 DoxX-like family An_peroxidase PF03098.10 KND89130.1 - 4.1e-08 32.0 0.0 5.9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase ADH_N PF08240.7 KND89130.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DPBB_1 PF03330.13 KND89132.1 - 4.3e-09 36.2 0.3 8.9e-09 35.2 0.2 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KND89132.1 - 0.016 14.8 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Barwin family Inhibitor_I68 PF10468.4 KND89132.1 - 0.033 14.3 0.2 0.047 13.8 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 DUF3883 PF13020.1 KND89133.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) Ribosomal_S14 PF00253.16 KND89134.1 - 3.9e-17 61.3 0.8 4e-16 58.1 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Peptidase_C14 PF00656.17 KND89139.1 - 1e-67 228.4 0.0 1.3e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Caspase domain APH PF01636.18 KND89140.1 - 6e-17 62.1 2.3 1.5e-16 60.9 1.4 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND89140.1 - 0.035 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase WW PF00397.21 KND89141.1 - 7.3e-08 32.1 4.0 7.3e-08 32.1 2.8 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 KND89141.1 - 0.03 14.3 15.5 0.11 12.5 10.8 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_OmpA PF13436.1 KND89141.1 - 3.5 7.3 8.2 0.8 9.3 2.8 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Ank_2 PF12796.2 KND89143.1 - 9.1e-61 202.2 11.2 4.1e-17 62.2 0.3 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KND89143.1 - 2.3e-48 159.6 17.7 4.4e-07 29.3 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KND89143.1 - 7.6e-39 131.4 3.9 4.1e-08 33.5 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89143.1 - 1.4e-32 108.4 3.2 0.0014 18.6 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KND89143.1 - 3e-24 84.4 10.0 2.2e-05 24.5 0.0 6.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) HEAT_2 PF13646.1 KND89143.1 - 2.5e-06 27.6 11.2 6.1e-06 26.4 0.8 4.0 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KND89143.1 - 0.00023 20.9 0.7 0.082 13.0 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 KND89143.1 - 0.12 12.9 11.0 2.3 8.8 1.8 4.5 3 1 1 4 4 4 0 HEAT-like repeat DUF1843 PF08898.5 KND89143.1 - 1.4 9.0 7.7 5.1 7.2 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) WD40 PF00400.27 KND89146.1 - 5.4e-14 51.4 3.7 8.5e-05 22.2 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KND89146.1 - 0.06 13.6 0.1 13 6.1 0.0 3.6 3 1 1 4 4 4 0 PQQ-like domain PQQ_2 PF13360.1 KND89146.1 - 0.11 11.8 0.0 0.55 9.6 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Complex1_LYR_1 PF13232.1 KND89149.1 - 6e-19 68.0 2.8 6e-19 68.0 1.9 2.1 2 1 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 KND89149.1 - 2.6e-18 65.5 2.7 2.6e-18 65.5 1.9 1.9 2 1 0 2 2 2 1 Complex 1 protein (LYR family) DUF1823 PF08853.6 KND89149.1 - 0.055 13.2 0.3 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Bys1 PF04681.7 KND89150.1 - 2.1e-18 66.5 0.4 2.3e-18 66.3 0.3 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Flagellar_rod PF05149.7 KND89152.1 - 0.0028 16.8 1.3 0.0038 16.4 0.9 1.1 1 0 0 1 1 1 1 Paraflagellar rod protein DUF3287 PF11690.3 KND89152.1 - 0.0036 17.3 0.8 0.02 14.9 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3287) Cluap1 PF10234.4 KND89152.1 - 0.013 14.7 0.8 0.017 14.3 0.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3584 PF12128.3 KND89152.1 - 0.039 11.3 0.3 0.043 11.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Consortin_C PF15281.1 KND89152.1 - 0.039 13.4 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 Consortin C-terminus Pyr_redox_3 PF13738.1 KND89154.1 - 3.5e-19 69.6 0.0 7.5e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KND89154.1 - 2.5e-14 52.4 0.2 2.9e-13 48.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND89154.1 - 9.7e-09 35.1 0.0 5.9e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KND89154.1 - 3.8e-05 22.7 0.1 0.00026 20.0 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KND89154.1 - 0.00085 19.2 0.0 0.0039 17.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND89154.1 - 0.0015 18.2 0.4 0.76 9.5 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KND89154.1 - 0.0022 16.9 0.1 1.2 8.0 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KND89154.1 - 0.073 11.5 0.3 0.69 8.3 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KND89154.1 - 0.31 11.4 1.4 21 5.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bac_luciferase PF00296.15 KND89155.1 - 3.5e-47 161.0 0.7 4.7e-47 160.5 0.5 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 KND89156.1 - 1.2e-12 47.2 31.5 1.2e-12 47.2 21.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KND89156.1 - 7.5e-05 22.2 3.1 7.5e-05 22.2 2.2 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 ATPase_gene1 PF09527.5 KND89156.1 - 0.11 12.3 0.3 0.11 12.3 0.2 4.8 5 0 0 5 5 5 0 Putative F0F1-ATPase subunit (ATPase_gene1) adh_short PF00106.20 KND89157.1 - 5.8e-27 94.6 0.2 7.6e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND89157.1 - 6.9e-17 62.0 0.0 9.3e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND89157.1 - 2.3e-14 53.4 0.3 7.2e-14 51.8 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND89157.1 - 0.00093 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND89157.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KND89158.1 - 0.17 11.9 0.2 0.79 9.7 0.0 1.9 1 1 1 2 2 2 0 TrkA-N domain Fungal_trans PF04082.13 KND89159.1 - 3.6e-16 58.8 0.1 6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89159.1 - 0.00017 21.4 2.4 0.00036 20.3 1.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 KND89160.1 - 2.5e-67 227.8 0.0 2.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KND89160.1 - 0.0011 18.6 0.2 0.0065 16.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND89160.1 - 0.008 15.4 0.3 0.017 14.3 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_3 PF01596.12 KND89161.1 - 8.8e-25 86.9 0.0 1.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KND89161.1 - 5.7e-17 62.4 0.0 9.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89161.1 - 4.2e-13 49.8 0.0 6.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89161.1 - 5.4e-12 45.5 0.0 6.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND89161.1 - 1.4e-05 24.7 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 KND89161.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KND89161.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89161.1 - 0.00058 20.1 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND89161.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89161.1 - 0.0033 17.8 0.0 0.0079 16.6 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND89161.1 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND89161.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.13 KND89161.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.4 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 CmcI PF04989.7 KND89161.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase MFS_1 PF07690.11 KND89162.1 - 4.8e-25 88.0 68.3 2.1e-21 76.0 35.7 3.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND89162.1 - 3.4e-09 35.8 10.0 3.4e-09 35.8 7.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter p450 PF00067.17 KND89163.1 - 2.7e-51 174.5 0.0 1.4e-40 139.1 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 Myco_arth_vir_N PF09610.5 KND89163.1 - 0.66 9.9 5.8 1.5 8.8 4.0 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF3418 PF11898.3 KND89164.1 - 0.13 10.5 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Amidohydro_2 PF04909.9 KND89168.1 - 1.1e-24 87.5 0.1 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KND89168.1 - 0.078 12.1 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 TatD related DNase AA_permease_2 PF13520.1 KND89169.1 - 3.8e-79 266.2 26.6 4.8e-79 265.8 18.4 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KND89171.1 - 2.3e-50 171.2 88.9 1.3e-42 145.8 39.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 KND89171.1 - 0.8 9.5 3.9 2.3 8.0 1.5 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TPT PF03151.11 KND89172.1 - 1.4e-22 79.9 14.4 1.4e-22 79.9 9.9 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KND89172.1 - 0.00053 19.0 17.8 0.0081 15.1 12.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KND89172.1 - 0.0009 19.2 9.9 0.0009 19.2 6.8 3.3 3 1 0 3 3 3 2 EamA-like transporter family DUF2868 PF11067.3 KND89174.1 - 1.4 7.9 16.3 0.082 12.0 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) zf-Di19 PF05605.7 KND89175.1 - 0.025 14.7 7.6 0.38 10.9 0.4 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KND89175.1 - 0.051 13.2 2.3 0.99 9.1 0.0 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KND89175.1 - 0.25 11.7 12.3 3.6 8.1 0.9 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KND89175.1 - 3.1 8.3 15.1 3.1 8.3 0.4 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Abhydrolase_1 PF00561.15 KND89176.1 - 7e-17 61.7 0.0 2.1e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND89176.1 - 3.1e-10 40.3 7.3 4.9e-09 36.4 5.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KND89176.1 - 0.00061 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-C3Hc3H PF13891.1 KND89177.1 - 0.092 12.8 2.2 0.14 12.2 1.5 1.2 1 0 0 1 1 1 0 Potential DNA-binding domain Glyco_hydro_12 PF01670.11 KND89178.1 - 1e-18 67.6 0.2 2.1e-18 66.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 F-box-like PF12937.2 KND89180.1 - 0.015 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 KND89180.1 - 0.016 14.8 0.0 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain F-box PF00646.28 KND89180.1 - 0.06 13.0 1.4 0.68 9.6 0.0 2.9 3 0 0 3 3 3 0 F-box domain Bac_rhamnosid PF05592.6 KND89181.1 - 5.7e-39 133.6 0.1 1.9e-32 112.1 0.9 3.1 2 2 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KND89181.1 - 0.00041 19.1 0.8 0.00077 18.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KND89181.1 - 0.0063 15.2 0.0 0.0091 14.7 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase ICL PF00463.16 KND89182.1 - 4.5e-190 632.3 0.0 5.2e-190 632.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Citrate_synt PF00285.16 KND89183.1 - 6e-98 327.8 0.0 7.2e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_16 PF00722.16 KND89184.1 - 1.1e-38 132.4 2.2 1.1e-38 132.4 1.5 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 KND89186.1 - 2.1e-27 95.9 0.0 5.4e-27 94.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89186.1 - 3.5e-08 32.8 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ras PF00071.17 KND89187.1 - 3.7e-50 169.4 0.0 4.6e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND89187.1 - 8.7e-16 58.5 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND89187.1 - 1.6e-06 27.4 0.0 3.3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND89187.1 - 0.0094 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND89187.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KND89187.1 - 0.052 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CWC25 PF12542.3 KND89188.1 - 4.6e-27 94.3 1.3 4.6e-27 94.3 0.9 3.9 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KND89188.1 - 7.7e-13 48.2 2.7 7.7e-13 48.2 1.9 3.9 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PAP_assoc PF03828.14 KND89190.1 - 5.1e-17 61.5 0.2 1.2e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KND89190.1 - 0.16 12.2 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain AhpC-TSA_2 PF13911.1 KND89191.1 - 1.4e-10 41.0 0.3 3.1e-10 39.9 0.2 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 KND89191.1 - 0.00026 20.5 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin SR-25 PF10500.4 KND89191.1 - 1.4 8.3 5.8 2.1 7.7 4.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2288 PF10052.4 KND89192.1 - 0.34 10.6 0.2 0.69 9.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Peptidase_S8 PF00082.17 KND89193.1 - 1.7e-53 181.5 7.3 2.5e-53 181.0 5.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND89193.1 - 2.7e-20 72.6 0.2 6.1e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 NADHdh_A3 PF14987.1 KND89194.1 - 0.058 13.3 0.2 0.071 13.0 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DDOST_48kD PF03345.9 KND89195.1 - 1.7e-139 465.0 0.0 2.5e-139 464.4 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.13 KND89195.1 - 9.9e-109 362.9 0.0 1.6e-108 362.2 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KND89195.1 - 1e-10 41.4 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KND89195.1 - 2.1e-10 41.0 0.0 4.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KND89195.1 - 4.3e-09 35.9 5.2 0.0065 16.3 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Zip PF02535.17 KND89196.1 - 0.22 10.5 10.5 0.31 9.9 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 KND89196.1 - 0.72 9.1 17.6 1.2 8.4 12.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 KND89196.1 - 1.2 7.8 29.2 1.9 7.2 20.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HAUS6_N PF14661.1 KND89196.1 - 1.9 7.7 13.8 2.8 7.2 9.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Hid1 PF12722.2 KND89196.1 - 5.8 4.4 10.5 7.9 4.0 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SE PF08491.5 KND89197.1 - 1.9e-15 56.4 0.0 2.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KND89197.1 - 0.047 12.5 0.0 0.33 9.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase EcKinase PF02958.15 KND89198.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PAF-AH_p_II PF03403.8 KND89199.1 - 2.3e-29 101.8 0.0 3.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KND89199.1 - 1.3e-11 44.4 0.3 2.4e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND89199.1 - 8.7e-07 29.0 6.1 2.1e-06 27.8 4.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KND89199.1 - 0.00081 18.3 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KND89199.1 - 0.0064 16.0 0.0 0.67 9.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KND89199.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_2 PF00703.16 KND89200.1 - 1.8e-08 34.8 0.0 4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KND89200.1 - 0.068 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain TPR_10 PF13374.1 KND89201.1 - 9.1e-16 57.2 0.1 1.2e-06 28.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND89201.1 - 6.1e-10 38.9 0.0 1.7e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.17 KND89201.1 - 5.1e-05 22.2 0.0 9.7e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 KND89201.1 - 0.0011 18.2 0.1 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KND89201.1 - 0.0031 17.4 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KND89201.1 - 0.0091 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-3CxxC PF13695.1 KND89202.1 - 5.7e-27 93.8 0.7 6.8e-27 93.5 0.5 1.1 1 0 0 1 1 1 1 Zinc-binding domain zf-tcix PF14952.1 KND89202.1 - 0.059 12.7 2.6 3.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding 2OG-FeII_Oxy PF03171.15 KND89203.1 - 0.00027 21.1 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KND89203.1 - 0.0013 19.1 0.1 0.0026 18.2 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chromo PF00385.19 KND89204.1 - 1.2e-12 47.3 1.5 3.8e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Asparaginase_II PF06089.7 KND89207.1 - 5.3e-51 173.2 0.5 5.9e-51 173.0 0.4 1.0 1 0 0 1 1 1 1 L-asparaginase II Asparaginase_II PF06089.7 KND89208.1 - 8.7e-41 139.6 0.1 9.4e-41 139.5 0.1 1.0 1 0 0 1 1 1 1 L-asparaginase II DUF1620 PF07774.8 KND89211.1 - 9.2e-59 198.3 0.0 1.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KND89211.1 - 1.8e-14 53.7 13.4 2e-09 37.2 2.0 3.5 2 2 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 KND89211.1 - 0.00047 19.5 9.2 0.19 11.3 0.0 5.0 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.1 KND89211.1 - 0.67 10.3 6.3 49 4.3 0.2 4.9 4 0 0 4 4 4 0 PQQ-like domain HATPase_c_3 PF13589.1 KND89214.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF914 PF06027.7 KND89216.1 - 4.1e-103 344.7 12.3 5.5e-103 344.3 8.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KND89216.1 - 2.2e-06 27.7 22.9 7.9e-06 25.9 2.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF1427 PF07235.6 KND89216.1 - 0.19 11.7 0.5 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Ninjurin PF04923.7 KND89216.1 - 0.34 10.6 0.0 0.34 10.6 0.0 2.2 3 0 0 3 3 3 0 Ninjurin TPT PF03151.11 KND89216.1 - 1.3 8.6 19.2 3.2 7.3 2.4 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family Metallophos PF00149.23 KND89218.1 - 7.4e-06 25.4 2.3 2e-05 24.1 1.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 KND89220.1 - 9.8e-30 103.6 10.4 1.5e-29 103.0 7.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND89220.1 - 2.4e-12 46.8 6.8 3.5e-12 46.3 4.7 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND89220.1 - 3.3e-11 43.4 0.0 4.3e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KND89220.1 - 8e-05 22.1 0.5 0.00013 21.4 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KND89220.1 - 0.0029 16.5 0.5 0.0047 15.8 0.4 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Methyltransf_26 PF13659.1 KND89220.1 - 0.0039 17.2 3.4 0.0064 16.5 2.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KND89220.1 - 0.0041 15.8 0.1 0.0054 15.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND89220.1 - 0.0086 15.0 1.0 0.051 12.4 0.3 2.3 1 1 1 2 2 2 1 Male sterility protein Methyltransf_18 PF12847.2 KND89220.1 - 0.023 15.2 0.2 0.042 14.4 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain Transketolase_C PF02780.15 KND89220.1 - 0.068 13.1 0.4 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Transketolase, C-terminal domain Eno-Rase_NADH_b PF12242.3 KND89220.1 - 0.089 12.5 2.3 0.27 11.0 1.6 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KND89220.1 - 0.098 12.3 0.9 0.16 11.5 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3494 PF11999.3 KND89221.1 - 3e-35 121.7 19.1 3.8e-35 121.3 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) DUF799 PF05643.6 KND89221.1 - 0.35 10.1 6.5 0.26 10.5 2.6 1.9 1 1 1 2 2 2 0 Putative bacterial lipoprotein (DUF799) zf-BED PF02892.10 KND89222.1 - 0.035 13.8 4.5 0.065 13.0 3.1 1.3 1 0 0 1 1 1 0 BED zinc finger ABC_tran PF00005.22 KND89223.1 - 3e-08 34.0 0.0 4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KND89223.1 - 0.0015 17.7 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KND89223.1 - 0.21 11.5 1.8 1.8 8.5 1.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ACT_3 PF10000.4 KND89225.1 - 5.1e-10 38.9 0.0 1.5e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 ACT domain HTH_29 PF13551.1 KND89225.1 - 3.3e-05 23.9 0.1 3.3e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 KND89225.1 - 0.00015 21.6 0.2 0.00026 20.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 KND89225.1 - 0.00023 20.6 0.1 0.00046 19.7 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.2 KND89225.1 - 0.04 13.5 0.1 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 MarR family ACT_7 PF13840.1 KND89225.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.7 1 1 1 2 2 2 0 ACT domain HTH_32 PF13565.1 KND89225.1 - 0.22 12.3 0.1 0.22 12.3 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF1689 PF07954.6 KND89226.1 - 0.0089 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) BTB PF00651.26 KND89229.1 - 1.7e-18 66.5 0.4 2.9e-18 65.8 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-HIT PF04438.11 KND89229.1 - 0.0025 17.4 5.2 0.095 12.3 0.5 2.5 2 0 0 2 2 2 2 HIT zinc finger DUF4206 PF13901.1 KND89229.1 - 0.022 14.3 2.6 0.044 13.3 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) TF_Zn_Ribbon PF08271.7 KND89229.1 - 0.023 14.0 1.1 0.051 12.8 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 KND89229.1 - 0.061 13.1 5.6 0.17 11.6 3.9 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 KND89229.1 - 0.068 12.6 2.5 0.073 12.5 0.8 1.8 2 0 0 2 2 2 0 Transposase zinc-binding domain Ribosomal_L37ae PF01780.14 KND89229.1 - 0.076 12.8 1.4 0.31 10.9 1.2 1.8 2 0 0 2 2 2 0 Ribosomal L37ae protein family Zn-ribbon_8 PF09723.5 KND89229.1 - 0.2 11.6 5.5 0.71 9.8 0.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 KND89229.1 - 0.28 11.0 4.1 0.3 10.9 1.2 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 KND89229.1 - 2.7 7.7 5.1 8.2 6.2 0.2 2.9 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) OrfB_Zn_ribbon PF07282.6 KND89229.1 - 3.2 7.4 6.8 4.8 6.9 3.4 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 KND89229.1 - 5.9 6.4 6.9 33 4.0 2.9 2.9 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Globin PF00042.17 KND89230.1 - 8.1e-12 45.4 0.1 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 KND89230.1 - 3.2e-07 30.8 0.0 6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KND89230.1 - 2e-05 24.6 0.0 5.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 KND89230.1 - 7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 KND89230.1 - 0.024 14.5 0.0 0.13 12.1 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DCD PF06559.6 KND89230.1 - 0.09 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MFS_1 PF07690.11 KND89231.1 - 7.1e-29 100.6 21.6 7.1e-29 100.6 15.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND89231.1 - 1.4e-06 27.2 7.6 1.4e-06 27.2 5.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KND89231.1 - 3.7e-06 25.5 0.0 0.021 13.2 1.0 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.13 KND89231.1 - 0.059 11.8 0.1 0.1 11.0 0.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier Acetyltransf_3 PF13302.1 KND89232.1 - 7.6e-14 52.0 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND89232.1 - 0.0003 20.7 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND89232.1 - 0.00045 20.1 0.1 0.00075 19.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KND89232.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 KND89233.1 - 1.4e-10 40.3 0.8 2.1e-10 39.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TerB-N PF13208.1 KND89233.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 TerB-N p450 PF00067.17 KND89234.1 - 8.7e-63 212.4 0.0 1e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.1 KND89235.1 - 4.9e-35 121.3 0.0 7.4e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KND89235.1 - 3e-20 72.7 0.1 3e-20 72.7 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 KND89235.1 - 3.7e-13 48.7 0.7 1.5e-09 36.7 0.0 3.1 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.1 KND89235.1 - 5.3e-12 45.3 0.0 9.3e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KND89235.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 KND89235.1 - 6e-05 21.6 0.1 0.0075 14.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_2 PF10111.4 KND89235.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.20 KND89237.1 - 1.6e-29 102.8 0.0 3.7e-28 98.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89237.1 - 2.9e-09 36.3 0.0 0.00058 19.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KND89237.1 - 0.00017 21.4 0.5 0.00064 19.5 0.1 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KND89237.1 - 0.053 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND89237.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PhyH PF05721.8 KND89238.1 - 2.4e-10 40.8 0.1 4.9e-10 39.7 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.16 KND89239.1 - 1.7e-119 399.3 32.1 1.9e-119 399.1 22.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND89239.1 - 1.4e-32 112.7 36.9 1.7e-32 112.4 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 KND89240.1 - 2.3e-10 40.6 0.4 3.7e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KND89240.1 - 1.3e-05 24.9 3.8 2.8e-05 23.8 2.6 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Coatomer_WDAD PF04053.9 KND89240.1 - 0.18 10.5 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Ank_2 PF12796.2 KND89241.1 - 1.4e-99 326.5 21.3 9.2e-23 80.4 0.0 5.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KND89241.1 - 1.1e-61 201.7 23.6 7.2e-10 38.1 0.0 11.0 10 1 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KND89241.1 - 2.6e-45 152.0 4.1 1.3e-14 54.1 0.0 8.6 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND89241.1 - 2.5e-44 148.2 11.3 5e-08 32.9 0.0 7.4 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89241.1 - 1.3e-41 136.4 1.6 5e-06 26.2 0.0 10.4 11 0 0 11 11 11 6 Ankyrin repeat RVP PF00077.15 KND89241.1 - 0.013 15.3 4.0 2.1 8.3 0.0 4.2 3 1 2 5 5 5 0 Retroviral aspartyl protease TAF1D PF15333.1 KND89242.1 - 0.024 14.4 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Fungal_trans PF04082.13 KND89243.1 - 9.1e-13 47.6 0.3 1.4e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89243.1 - 1.3e-09 37.7 7.9 2.6e-09 36.8 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF5 PF04855.7 KND89244.1 - 0.0019 17.7 0.2 1.6 8.1 0.0 2.1 1 1 0 2 2 2 2 SNF5 / SMARCB1 / INI1 PsaN PF05479.6 KND89244.1 - 0.034 14.1 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF2862 PF11061.3 KND89244.1 - 0.11 12.1 3.3 4.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) MFS_1 PF07690.11 KND89245.1 - 3.9e-56 190.2 85.1 8.8e-46 156.2 37.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 KND89246.1 - 3.4e-12 46.0 0.2 1.9e-11 43.5 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND89246.1 - 4.3e-07 30.8 0.0 1e-06 29.6 0.0 1.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND89246.1 - 1.3e-06 28.1 0.0 9e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KND89246.1 - 4.1e-06 26.9 0.1 6.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND89246.1 - 0.0079 15.6 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND89246.1 - 0.05 12.8 0.1 0.073 12.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KND89246.1 - 0.063 13.1 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KND89246.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_binding_6 PF00970.19 KND89247.1 - 2.6e-09 37.1 0.0 6e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KND89247.1 - 3.9e-06 27.3 0.0 2.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 KND89247.1 - 1e-05 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Globin Protoglobin PF11563.3 KND89247.1 - 0.00027 20.6 0.0 0.00066 19.3 0.0 1.7 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 KND89247.1 - 0.0036 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_MLP1_2 PF07926.7 KND89248.1 - 0.0036 17.0 2.0 0.017 14.8 1.4 2.2 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein RPW8 PF05659.6 KND89248.1 - 0.017 14.6 1.0 0.061 12.8 0.1 2.3 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SYCE1 PF15233.1 KND89248.1 - 0.046 13.6 1.3 0.092 12.6 0.9 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 LOH1CR12 PF10158.4 KND89248.1 - 0.054 13.2 0.7 0.22 11.3 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein ADIP PF11559.3 KND89248.1 - 0.06 13.2 0.9 0.13 12.1 0.6 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Snapin_Pallidin PF14712.1 KND89248.1 - 0.38 11.0 3.6 11 6.4 1.7 2.9 2 1 0 2 2 2 0 Snapin/Pallidin COG2 PF06148.6 KND89248.1 - 2 8.2 6.2 3.2 7.6 0.1 3.7 3 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.4 KND89248.1 - 2.2 8.4 8.5 4.4 7.5 0.6 3.5 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 KND89248.1 - 3.3 7.8 5.8 20 5.3 2.4 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 KND89249.1 - 1.1e-60 199.4 26.9 5.8e-13 48.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KND89249.1 - 2.7e-10 38.9 12.6 0.035 12.2 0.1 5.1 2 2 3 5 5 5 5 Nucleoporin Nup120/160 Reovirus_L2 PF06016.6 KND89249.1 - 0.049 10.6 0.1 0.062 10.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) NAGLU PF05089.7 KND89250.1 - 1.3e-123 412.0 9.2 2e-123 411.4 6.4 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 KND89250.1 - 2.3e-68 230.4 6.1 3.8e-68 229.7 4.2 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 KND89250.1 - 5.6e-17 61.1 0.1 2.5e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Tropomyosin_1 PF12718.2 KND89251.1 - 2.4e-06 27.4 28.7 0.00022 21.0 10.6 2.6 1 1 1 2 2 2 2 Tropomyosin like Reo_sigmaC PF04582.7 KND89251.1 - 0.0087 15.2 10.6 0.012 14.8 4.5 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein ATG16 PF08614.6 KND89251.1 - 0.01 15.7 3.2 0.01 15.7 2.2 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Det1 PF09737.4 KND89251.1 - 0.051 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 SLT_beta PF02258.11 KND89251.1 - 0.066 13.0 0.1 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Shiga-like toxin beta subunit Myosin_tail_1 PF01576.14 KND89251.1 - 0.44 8.2 33.7 2.3 5.8 23.3 1.8 1 1 0 1 1 1 0 Myosin tail Atg14 PF10186.4 KND89251.1 - 0.45 9.4 22.0 0.057 12.3 7.0 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KND89251.1 - 0.68 8.5 29.2 2.1 6.9 11.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KND89251.1 - 3.9 7.6 22.3 3.1 7.9 1.5 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ERM PF00769.14 KND89251.1 - 5.2 6.5 24.7 6.1 6.3 2.1 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family APH PF01636.18 KND89253.1 - 0.0016 18.2 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KND89253.1 - 0.0041 15.8 0.0 0.0047 15.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 KND89253.1 - 0.0078 15.2 0.0 0.0093 14.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase IlvC PF01450.14 KND89253.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ATPgrasp_Ter PF15632.1 KND89253.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Abhydrolase_2 PF02230.11 KND89255.1 - 9.1e-25 87.3 0.0 2.1e-16 60.0 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KND89255.1 - 3.9e-09 36.0 0.0 1.1e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KND89255.1 - 1.6e-07 31.4 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89255.1 - 9.9e-07 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KND89255.1 - 0.00015 21.4 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KND89255.1 - 0.0075 15.5 0.0 0.027 13.7 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family LIP PF03583.9 KND89255.1 - 0.066 12.3 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Isy1 PF06246.7 KND89257.1 - 5.8e-88 294.5 0.5 7.8e-88 294.1 0.3 1.2 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 KND89257.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein IncA PF04156.9 KND89258.1 - 0.0015 18.1 5.3 0.12 12.0 0.1 2.2 2 0 0 2 2 2 2 IncA protein Striatin PF08232.7 KND89258.1 - 0.0042 17.4 0.9 0.0042 17.4 0.6 2.1 2 0 0 2 2 2 1 Striatin family Sigma70_ner PF04546.8 KND89258.1 - 0.0097 15.5 2.4 0.017 14.7 0.3 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region bZIP_1 PF00170.16 KND89258.1 - 0.029 14.3 0.4 0.075 13.0 0.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor Syntaxin PF00804.20 KND89258.1 - 0.039 14.1 1.5 1 9.5 0.1 2.4 2 0 0 2 2 2 0 Syntaxin Tropomyosin_1 PF12718.2 KND89258.1 - 0.049 13.4 0.6 0.049 13.4 0.4 2.1 2 0 0 2 2 2 0 Tropomyosin like Uso1_p115_C PF04871.8 KND89258.1 - 0.057 13.3 0.3 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TBPIP PF07106.8 KND89258.1 - 0.059 12.9 1.1 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 KND89258.1 - 0.17 11.7 0.1 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 KND89258.1 - 0.18 10.2 0.1 0.3 9.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 KND89258.1 - 0.26 11.6 2.8 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) GrpE PF01025.14 KND89258.1 - 0.28 10.7 5.9 0.62 9.5 0.9 2.2 2 0 0 2 2 2 0 GrpE DivIC PF04977.10 KND89258.1 - 0.29 10.6 6.8 0.12 11.8 1.5 2.5 2 1 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 KND89258.1 - 0.3 10.9 2.7 0.21 11.3 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 KND89258.1 - 0.35 11.3 3.0 1 9.8 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PLA2_B PF01735.13 KND89261.1 - 3.7e-173 576.2 0.1 4.3e-173 575.9 0.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Borrelia_P83 PF05262.6 KND89262.1 - 0.25 9.5 2.8 0.38 8.9 2.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TEBP_beta PF07404.6 KND89262.1 - 0.28 10.2 2.0 0.41 9.7 1.4 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) GFO_IDH_MocA PF01408.17 KND89263.1 - 6.6e-27 94.4 0.1 1e-26 93.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KND89263.1 - 3.5e-12 46.1 0.1 7.7e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KND89263.1 - 6.9e-06 26.4 0.3 1.9e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KND89263.1 - 1e-05 25.8 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KND89263.1 - 0.029 14.2 0.1 0.096 12.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KND89263.1 - 0.036 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 KND89263.1 - 0.045 14.1 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 KND89263.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain AlaDh_PNT_N PF05222.10 KND89264.1 - 6.9e-18 64.9 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KND89264.1 - 3.3e-12 46.2 0.0 5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Zeta_toxin PF06414.7 KND89264.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MFS_1 PF07690.11 KND89265.1 - 8.5e-34 116.7 31.3 8.7e-34 116.7 21.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC12 PF06645.8 KND89265.1 - 0.0038 16.9 0.6 1.6 8.6 0.0 3.4 2 1 1 3 3 3 2 Microsomal signal peptidase 12 kDa subunit (SPC12) PepSY_TM_2 PF13703.1 KND89265.1 - 0.13 12.4 5.0 0.12 12.5 0.5 3.3 4 1 0 4 4 4 0 PepSY-associated TM helix GTP_cyclohydroI PF01227.17 KND89266.1 - 5.3e-73 244.1 0.3 6.8e-73 243.7 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KND89266.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein NAD_kinase PF01513.16 KND89267.1 - 1.6e-42 145.2 0.0 4.1e-42 143.9 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 KND89268.1 - 5.4e-26 90.6 0.0 7.6e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2305 PF10230.4 KND89269.1 - 3.9e-49 167.4 0.0 4.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KND89269.1 - 0.00039 20.3 2.8 0.00053 19.9 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89269.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family CFEM PF05730.6 KND89270.1 - 5.1e-13 48.6 11.9 8.2e-13 47.9 8.3 1.3 1 0 0 1 1 1 1 CFEM domain DUF2845 PF11006.3 KND89270.1 - 0.071 12.9 0.5 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) Peptidase_C34 PF05413.6 KND89270.1 - 0.13 12.3 0.6 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase DEC-1_N PF04625.8 KND89270.1 - 0.76 8.3 12.2 1.1 7.8 8.5 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2076 PF09849.4 KND89270.1 - 1.6 8.7 7.7 2.1 8.3 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF605 PF04652.11 KND89270.1 - 3.7 6.8 11.9 4.5 6.5 8.3 1.1 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 KND89272.1 - 1.6e-11 43.6 0.1 3.6e-08 32.9 0.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KND89272.1 - 8.9e-10 37.7 2.6 0.00059 19.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND89272.1 - 2e-06 27.1 0.1 0.096 12.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND89272.1 - 4e-05 23.4 0.1 0.0024 17.7 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND89272.1 - 0.00047 20.4 0.1 0.0044 17.3 0.0 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND89272.1 - 0.0014 19.0 7.3 0.026 15.1 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND89272.1 - 0.0022 18.6 8.0 0.0037 17.8 0.3 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KND89272.1 - 0.0027 17.5 3.0 0.79 9.6 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND89272.1 - 0.0066 16.1 0.0 0.36 10.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KND89272.1 - 0.087 13.3 1.7 5.5 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND89272.1 - 0.2 12.1 1.4 4.2 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.13 KND89273.1 - 2.1e-27 95.7 0.0 3.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 BAG PF02179.11 KND89273.1 - 1.1e-17 63.9 0.0 2.9e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KND89273.1 - 0.0003 20.1 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DSBA PF01323.15 KND89273.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Chalcone PF02431.10 KND89274.1 - 3.8e-59 199.4 0.0 5.2e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Aldedh PF00171.17 KND89275.1 - 1.9e-143 478.1 0.0 2.2e-143 477.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2108 PF09881.4 KND89275.1 - 0.16 11.8 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) Melibiase PF02065.13 KND89276.1 - 2.6e-153 510.3 0.0 3.5e-153 509.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase F-box-like PF12937.2 KND89276.1 - 1.1e-12 47.3 0.5 3.4e-12 45.8 0.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KND89276.1 - 1.1e-06 28.1 18.7 3.7 7.9 0.0 9.7 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.2 KND89276.1 - 2.2e-05 23.9 7.3 0.42 10.2 0.0 6.0 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) F-box PF00646.28 KND89276.1 - 4.8e-05 22.8 0.2 0.00016 21.2 0.2 1.9 1 0 0 1 1 1 1 F-box domain DUF187 PF02638.10 KND89276.1 - 0.00019 20.4 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 LRR_8 PF13855.1 KND89276.1 - 0.0005 19.7 15.3 0.4 10.4 0.6 5.1 3 1 3 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 KND89276.1 - 2.1 8.6 23.0 21 5.6 0.1 8.6 7 3 1 8 8 8 0 Leucine Rich Repeat Ammonium_transp PF00909.16 KND89277.1 - 1.9e-118 395.4 23.2 2.2e-118 395.2 16.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pept_tRNA_hydro PF01195.14 KND89278.1 - 2.7e-31 108.4 0.0 3.3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DCP1 PF06058.8 KND89279.1 - 1.4e-17 63.8 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family BAR PF03114.13 KND89280.1 - 8.5e-63 211.9 4.2 1e-62 211.6 2.9 1.1 1 0 0 1 1 1 1 BAR domain tRNA-synt_2 PF00152.15 KND89281.1 - 4.8e-73 245.8 0.0 1.4e-72 244.2 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND89281.1 - 6.1e-07 29.2 0.2 1.2e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KND89281.1 - 0.11 11.6 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ADP_ribosyl_GH PF03747.9 KND89282.1 - 1.5e-58 198.8 7.2 1.8e-58 198.6 5.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sec23_trunk PF04811.10 KND89283.1 - 4.5e-49 166.9 0.0 1e-48 165.8 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KND89283.1 - 7.5e-24 83.1 0.1 1.3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KND89283.1 - 3.2e-18 66.0 0.0 5.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KND89283.1 - 2.6e-16 58.9 4.7 5.3e-16 57.9 3.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KND89283.1 - 3.1e-07 29.9 0.0 7.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.4 KND89284.1 - 1.3e-11 44.6 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Linker_histone PF00538.14 KND89286.1 - 7e-23 80.5 0.2 1.7e-22 79.2 0.2 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family Rifin_STEVOR PF02009.11 KND89286.1 - 0.11 12.0 7.3 0.14 11.8 5.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Dicty_REP PF05086.7 KND89286.1 - 8.7 3.9 10.4 12 3.4 7.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LrgB PF04172.11 KND89288.1 - 9.9e-24 83.6 9.9 9.9e-24 83.6 6.9 2.6 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.9 KND89288.1 - 0.0088 15.7 6.9 0.0088 15.7 4.8 2.9 3 0 0 3 3 3 1 LrgA family Asp PF00026.18 KND89290.1 - 2.5e-108 362.0 0.0 3e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND89290.1 - 2.9e-10 40.3 0.0 1.6e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND89290.1 - 6e-06 26.6 0.1 0.078 13.4 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KND89290.1 - 2.3e-05 24.0 0.0 0.00024 20.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KND89290.1 - 0.017 14.8 0.1 7.3 6.4 0.0 2.7 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Alpha-amylase_C PF02806.13 KND89290.1 - 0.057 13.5 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain AAA PF00004.24 KND89291.1 - 4.3e-45 153.1 0.4 1.4e-44 151.4 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND89291.1 - 5e-09 36.0 0.3 1.8e-08 34.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND89291.1 - 6.7e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KND89291.1 - 5.6e-07 29.7 0.0 1.7e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND89291.1 - 1.1e-06 28.7 0.6 0.00032 20.8 0.4 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KND89291.1 - 4e-06 25.9 0.0 8.5e-06 24.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KND89291.1 - 0.00029 20.7 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KND89291.1 - 0.00054 19.6 0.6 0.063 12.9 0.0 3.3 4 0 0 4 4 4 1 NACHT domain AAA_28 PF13521.1 KND89291.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND89291.1 - 0.00066 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KND89291.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 KND89291.1 - 0.0014 19.3 0.0 0.0062 17.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KND89291.1 - 0.0015 18.1 0.2 0.0042 16.8 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KND89291.1 - 0.0016 17.2 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_23 PF13476.1 KND89291.1 - 0.0036 17.6 0.1 0.98 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KND89291.1 - 0.0038 16.9 0.9 0.0087 15.7 0.0 2.1 3 0 0 3 3 1 1 NTPase Zeta_toxin PF06414.7 KND89291.1 - 0.0051 15.9 0.1 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 KND89291.1 - 0.0053 16.3 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KND89291.1 - 0.0054 16.3 0.6 0.018 14.5 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KND89291.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KND89291.1 - 0.0065 16.1 0.4 0.058 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 KND89291.1 - 0.0073 15.9 0.0 0.052 13.1 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KND89291.1 - 0.0081 15.3 0.1 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND89291.1 - 0.0083 15.5 0.8 0.09 12.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KND89291.1 - 0.012 15.0 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KND89291.1 - 0.013 15.0 0.2 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.9 KND89291.1 - 0.014 13.7 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_30 PF13604.1 KND89291.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 KND89291.1 - 0.021 13.6 0.0 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.13 KND89291.1 - 0.038 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 KND89291.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KND89291.1 - 0.05 12.7 1.4 0.55 9.3 0.0 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 KND89291.1 - 0.068 12.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KND89291.1 - 0.087 12.8 0.0 0.51 10.3 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Cast PF10174.4 KND89291.1 - 0.099 10.6 2.0 0.12 10.3 0.7 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Folliculin PF11704.3 KND89292.1 - 4.4e-27 94.7 0.0 8.3e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Acyl-CoA_dh_1 PF00441.19 KND89293.1 - 2e-41 141.5 0.2 2.8e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND89293.1 - 4.4e-21 75.5 0.0 8.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KND89293.1 - 1.1e-20 72.8 0.2 2.1e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KND89293.1 - 3.4e-19 68.4 0.3 6.2e-19 67.5 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KND89293.1 - 1.4e-07 31.8 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.24 KND89294.1 - 9.4e-43 145.6 0.0 1.4e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND89294.1 - 2.9e-24 84.7 0.1 5.4e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WSC PF01822.14 KND89295.1 - 1.3e-11 44.2 8.2 1.3e-11 44.2 5.7 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 KND89295.1 - 6.4e-07 28.5 0.5 1.3e-06 27.5 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KND89295.1 - 0.0008 19.0 0.1 0.0018 17.8 0.1 1.5 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.13 KND89295.1 - 0.00091 18.9 0.2 0.0019 17.9 0.2 1.5 1 0 0 1 1 1 1 Glycophorin A DUF566 PF04484.7 KND89295.1 - 0.1 12.0 0.2 0.1 12.0 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF566) DUF2076 PF09849.4 KND89295.1 - 0.26 11.3 3.6 0.082 12.9 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.8 KND89295.1 - 0.3 11.1 5.7 0.21 11.6 1.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.6 KND89295.1 - 1.6 8.5 11.6 0.05 13.4 3.6 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) XPG_I PF00867.13 KND89296.1 - 3.4e-30 103.9 0.0 9.5e-30 102.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KND89296.1 - 3.3e-27 94.7 0.0 9.8e-27 93.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KND89296.1 - 1.7e-06 28.2 0.4 9.7e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Mis14 PF08641.7 KND89297.1 - 0.00025 21.1 0.2 0.0005 20.1 0.1 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like IGF2_C PF08365.6 KND89297.1 - 2.3 8.0 6.0 5.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide DUF155 PF02582.9 KND89299.1 - 1.4e-40 139.0 0.0 2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CRAL_TRIO PF00650.15 KND89300.1 - 2.1e-35 121.5 0.0 3.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND89300.1 - 6e-09 35.8 0.1 2.1e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KND89300.1 - 0.00016 21.5 0.0 0.00036 20.4 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Serum_albumin PF00273.15 KND89300.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Serum albumin family Aldo_ket_red PF00248.16 KND89302.1 - 1.1e-51 175.3 0.0 1.4e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Death PF00531.17 KND89302.1 - 0.018 14.7 0.0 12 5.7 0.0 3.3 3 0 0 3 3 3 0 Death domain Pyridoxal_deC PF00282.14 KND89303.1 - 3.6e-68 229.7 0.0 5.2e-66 222.6 0.0 2.3 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KND89303.1 - 1.7e-05 23.7 0.0 3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KND89303.1 - 9.3e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.17 KND89304.1 - 1.5e-39 134.9 0.0 2e-25 89.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KND89304.1 - 1.7e-12 47.8 0.0 3.7e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KND89304.1 - 0.00062 19.0 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND89304.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND89304.1 - 0.024 14.0 0.0 0.82 9.0 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 KND89304.1 - 0.051 13.1 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T_hemolysin PF12261.3 KND89304.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin AMMECR1 PF01871.12 KND89305.1 - 4e-44 149.7 0.0 1.1e-43 148.2 0.0 1.6 2 0 0 2 2 2 1 AMMECR1 Crystall PF00030.14 KND89305.1 - 0.1 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF4006 PF13179.1 KND89306.1 - 0.032 13.7 0.1 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) JAB PF01398.16 KND89307.1 - 2.5e-13 49.7 0.0 4.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KND89307.1 - 3.4e-07 30.2 0.0 6.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KND89307.1 - 1.6e-06 27.6 0.0 4.8e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4398 PF14346.1 KND89307.1 - 0.73 9.9 7.3 9.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) An_peroxidase PF03098.10 KND89308.1 - 5.8e-96 321.9 0.0 9.9e-94 314.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KND89308.1 - 0.21 10.0 0.0 0.44 8.9 0.0 1.5 2 0 0 2 2 2 0 Cytochrome P450 NACHT PF05729.7 KND89309.1 - 2.2e-13 50.2 0.6 6.4e-13 48.6 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KND89309.1 - 0.00035 20.7 0.2 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KND89309.1 - 0.014 15.5 0.1 0.07 13.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KND89309.1 - 0.042 13.8 2.4 0.23 11.4 0.0 3.4 4 1 0 4 4 4 0 AAA ATPase domain AAA_19 PF13245.1 KND89309.1 - 0.052 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 KND89309.1 - 0.074 12.0 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KND89309.1 - 0.17 11.7 1.2 5 7.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain PUF PF00806.14 KND89310.1 - 3.5e-14 51.3 0.1 0.074 12.5 0.0 7.0 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat DnaJ PF00226.26 KND89312.1 - 1.6e-07 30.9 0.3 3.7e-07 29.7 0.2 1.7 1 1 0 1 1 1 1 DnaJ domain Auxin_repressed PF05564.7 KND89312.1 - 3.3 8.3 9.3 2.2 8.8 4.9 1.9 1 1 0 1 1 1 0 Dormancy/auxin associated protein UCH PF00443.24 KND89313.1 - 1.7e-40 138.8 0.0 3.4e-40 137.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND89313.1 - 3.3e-15 56.3 0.0 2.1e-07 30.6 0.0 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KND89313.1 - 2e-07 30.3 1.1 0.0031 16.8 0.0 3.0 3 0 0 3 3 3 2 A repeated domain in UCH-protein ECH PF00378.15 KND89314.1 - 2e-47 161.3 0.1 6.8e-44 149.8 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DUF917 PF06032.7 KND89315.1 - 4.3e-106 354.4 0.3 8.2e-106 353.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KND89315.1 - 2.1e-49 168.1 2.0 1e-47 162.6 0.4 3.1 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KND89315.1 - 2.5e-28 98.7 0.1 2.4e-25 89.0 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 KND89315.1 - 9.1e-06 25.1 0.7 0.00093 18.5 0.1 3.0 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 KND89315.1 - 0.00033 19.0 0.2 0.0095 14.2 0.0 2.2 2 0 0 2 2 2 1 MutL protein StbA PF06406.6 KND89315.1 - 0.0035 16.3 0.0 0.42 9.4 0.0 2.3 2 0 0 2 2 2 2 StbA protein Ank_2 PF12796.2 KND89317.1 - 9.8e-33 112.3 0.0 5.6e-09 36.2 0.0 5.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND89317.1 - 1.1e-23 82.7 4.2 1.7e-05 24.8 0.0 8.2 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 KND89317.1 - 1.1e-23 81.7 15.0 0.00014 21.5 0.0 9.6 10 3 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 KND89317.1 - 4.2e-22 78.0 2.2 3.8e-05 24.0 0.0 7.9 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89317.1 - 4.1e-20 69.8 1.3 0.0023 18.0 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Cwf_Cwc_15 PF04889.7 KND89317.1 - 0.63 9.7 7.4 0.95 9.1 5.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_2 PF12796.2 KND89318.1 - 3.7e-21 75.2 0.0 8.1e-08 32.5 0.1 4.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND89318.1 - 6.1e-20 69.9 8.2 5.7e-05 22.7 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KND89318.1 - 7.1e-17 61.4 2.6 0.0022 18.4 0.0 6.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89318.1 - 3.1e-12 45.4 1.1 0.035 14.3 0.0 7.5 7 1 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 KND89318.1 - 8.3e-08 32.2 0.8 0.82 10.0 0.0 6.7 7 1 0 7 7 7 2 Ankyrin repeats (many copies) F-box-like PF12937.2 KND89318.1 - 8.2e-05 22.2 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND89318.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 KND89318.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 PRANC domain Grp1_Fun34_YaaH PF01184.14 KND89319.1 - 2.1e-53 180.7 17.8 2.8e-53 180.3 12.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2254 PF10011.4 KND89319.1 - 0.0013 17.3 5.3 0.0013 17.3 3.7 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2254) Podoplanin PF05808.6 KND89320.1 - 0.0035 16.9 3.0 0.0098 15.4 2.1 1.7 1 1 0 1 1 1 1 Podoplanin P12 PF12669.2 KND89320.1 - 0.18 12.0 0.7 0.27 11.4 0.5 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family HET PF06985.6 KND89321.1 - 1.7e-26 93.0 0.9 2.7e-25 89.1 0.6 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldose_epim PF01263.15 KND89322.1 - 5.4e-63 212.8 0.0 7.1e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Frag1 PF10277.4 KND89323.1 - 1.1e-41 142.6 7.9 1.1e-41 142.6 5.4 2.8 3 0 0 3 3 3 2 Frag1/DRAM/Sfk1 family p450 PF00067.17 KND89324.1 - 3.8e-58 197.1 0.0 5.1e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.19 KND89325.1 - 1.2e-06 28.0 3.0 2.7e-06 26.9 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 KND89325.1 - 0.0099 16.1 43.2 0.0099 16.1 29.9 5.5 3 1 3 6 6 6 3 Nucleoporin FG repeat region zf-CCCH_2 PF14608.1 KND89325.1 - 3.4 7.7 6.1 3.7 7.7 2.7 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type CUE PF02845.11 KND89327.1 - 1.7e-10 40.1 0.1 3.4e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF1744 PF08490.7 KND89329.1 - 5.6e-132 440.0 0.1 4.7e-130 433.7 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KND89329.1 - 7.6e-63 212.3 0.6 1.4e-62 211.5 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KND89329.1 - 7.2e-23 81.1 0.2 4.1e-21 75.3 0.3 2.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KND89329.1 - 8.7e-09 35.2 0.2 2.1e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KND89329.1 - 1.9e-05 24.5 0.1 6.2e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 KND89330.1 - 8.5e-36 122.1 0.1 1.2e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3529 PF12046.3 KND89330.1 - 0.00021 20.3 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3529) DUF2244 PF10003.4 KND89330.1 - 0.08 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2368 PF10166.4 KND89330.1 - 1 8.9 4.1 13 5.4 3.5 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2368) Coq4 PF05019.8 KND89331.1 - 9.7e-09 34.4 0.1 0.0028 16.5 0.1 2.1 1 1 1 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TPR_12 PF13424.1 KND89334.1 - 0.01 15.7 2.6 16 5.5 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND89334.1 - 0.041 13.8 0.3 35 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HD_5 PF13487.1 KND89334.1 - 0.11 12.4 0.4 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 HD domain Myosin_tail_1 PF01576.14 KND89337.1 - 0.0034 15.1 5.2 0.0047 14.7 3.6 1.1 1 0 0 1 1 1 1 Myosin tail DUF4254 PF14063.1 KND89337.1 - 0.014 15.0 0.5 0.025 14.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DUF3450 PF11932.3 KND89337.1 - 0.19 10.9 5.4 0.25 10.5 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.1 KND89337.1 - 0.57 10.3 5.8 0.34 11.0 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) APH PF01636.18 KND89338.1 - 4.4e-05 23.3 0.3 4.4e-05 23.3 0.2 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF413 PF04219.7 KND89338.1 - 0.13 12.0 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF Fungal_trans PF04082.13 KND89339.1 - 5.7e-20 71.2 0.0 8.6e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 KND89339.1 - 0.038 13.9 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4643 PF15485.1 KND89340.1 - 0.15 11.5 5.8 0.17 11.3 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) FAD_binding_3 PF01494.14 KND89341.1 - 3.2e-77 259.9 0.0 7.5e-77 258.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KND89341.1 - 2.8e-39 134.4 0.0 8.1e-39 132.9 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KND89341.1 - 1.4e-05 24.3 0.0 0.0051 15.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KND89341.1 - 0.0039 16.1 0.0 0.04 12.7 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 KND89341.1 - 0.0047 15.8 0.0 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND89341.1 - 0.0062 15.0 0.0 0.0091 14.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KND89341.1 - 0.0097 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KND89341.1 - 0.0097 15.8 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND89341.1 - 0.011 14.6 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KND89341.1 - 0.014 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND89341.1 - 0.016 15.2 0.0 0.053 13.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KND89341.1 - 0.04 12.9 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MobB PF03205.9 KND89342.1 - 0.0037 16.9 0.1 0.045 13.4 0.0 2.6 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KND89342.1 - 0.0057 16.1 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Clp1 PF06807.9 KND89342.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 AAA_17 PF13207.1 KND89342.1 - 0.039 14.7 0.0 0.09 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND89342.1 - 0.041 13.8 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KND89342.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Fungal_trans PF04082.13 KND89343.1 - 2.5e-18 65.8 1.8 4.3e-18 65.1 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_binding_1 PF01035.15 KND89343.1 - 0.011 15.4 0.5 0.068 12.9 0.1 2.4 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Zn_clus PF00172.13 KND89343.1 - 0.014 15.2 16.8 0.027 14.3 11.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.16 KND89344.1 - 3e-11 43.1 7.5 3e-11 43.1 5.2 2.4 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KND89344.1 - 9.9e-07 28.4 7.8 2.6e-06 27.0 5.4 1.7 1 1 0 1 1 1 1 PAP2 superfamily RNA_polI_A34 PF08208.6 KND89345.1 - 1.4e-25 90.1 13.8 1.4e-25 90.1 9.6 5.6 3 2 1 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 PIP5K PF01504.13 KND89346.1 - 4.3e-86 288.1 0.1 7e-86 287.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.20 KND89347.1 - 4.3e-68 229.2 0.0 5.5e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89347.1 - 2.1e-28 99.1 0.0 2.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND89347.1 - 1.4e-06 27.4 0.0 2.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND89347.1 - 0.00032 20.5 0.1 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND89347.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KND89347.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3665 PF12427.3 KND89347.1 - 0.1 11.9 0.5 0.22 10.9 0.4 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Hydantoinase_B PF02538.9 KND89348.1 - 6.3e-181 602.1 0.0 8.5e-181 601.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KND89348.1 - 3.3e-93 311.9 0.1 9.7e-93 310.4 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KND89348.1 - 2.3e-55 186.8 0.1 8.7e-54 181.6 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region 5_nucleotid_C PF02872.13 KND89349.1 - 4.6e-33 114.3 0.2 1e-32 113.3 0.1 1.6 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KND89349.1 - 1e-08 34.8 0.1 1.7e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.1 KND89349.1 - 0.03 13.3 0.6 0.067 12.2 0.4 1.6 1 1 0 1 1 1 0 YmdB-like protein Adap_comp_sub PF00928.16 KND89350.1 - 7.9e-82 274.2 0.0 1e-81 273.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KND89350.1 - 2.8e-05 23.8 0.3 5.3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Zn_clus PF00172.13 KND89351.1 - 0.2 11.5 8.4 0.41 10.5 5.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 KND89352.1 - 5.1e-15 56.0 0.6 8.6e-15 55.3 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M28 PF04389.12 KND89353.1 - 1.3e-33 116.1 0.1 2.8e-33 115.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KND89353.1 - 0.0059 16.1 0.1 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KND89353.1 - 0.23 10.1 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase KH_1 PF00013.24 KND89354.1 - 5.7e-07 29.0 0.1 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KND89354.1 - 0.00019 20.9 0.1 0.00044 19.8 0.0 1.6 1 0 0 1 1 1 1 KH domain MFS_1 PF07690.11 KND89355.1 - 2.5e-31 108.6 26.7 2.5e-31 108.6 18.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily A_deaminase PF00962.17 KND89356.1 - 6.7e-39 133.7 0.0 1.1e-38 133.0 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase Lipase_3 PF01764.20 KND89357.1 - 7.5e-17 61.2 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Fungal_trans PF04082.13 KND89358.1 - 4.7e-14 51.8 2.9 9.7e-14 50.8 2.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89358.1 - 2e-10 40.4 10.6 3.1e-10 39.7 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KND89358.1 - 1.4 8.2 7.3 2.2 7.6 5.1 1.2 1 0 0 1 1 1 0 Vta1 like TauD PF02668.11 KND89360.1 - 9.2e-28 97.6 0.1 1.2e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KND89360.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 KND89360.1 - 0.1 13.1 0.4 0.36 11.3 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Amidohydro_1 PF01979.15 KND89364.1 - 2.5e-27 96.4 0.3 3.5e-27 95.9 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KND89364.1 - 1.1e-11 45.2 3.8 2.8e-09 37.4 2.6 3.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KND89364.1 - 2.9e-05 23.8 0.8 0.00037 20.2 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 KND89364.1 - 3.5e-05 23.2 0.4 0.0042 16.3 0.2 2.5 2 1 0 2 2 2 2 Amidohydrolase family MIP PF00230.15 KND89365.1 - 1.4e-47 162.0 16.6 1.7e-47 161.8 11.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DSBA PF01323.15 KND89366.1 - 1.1e-33 116.4 0.0 1.2e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 KND89366.1 - 0.0017 18.5 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Gti1_Pac2 PF09729.4 KND89367.1 - 1.7e-49 167.8 2.0 4.1e-47 160.1 1.4 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family PLDc_2 PF13091.1 KND89369.1 - 2.1e-17 63.0 0.0 2.3e-10 40.3 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KND89369.1 - 0.00016 21.3 0.1 0.53 10.1 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Prefoldin_2 PF01920.15 KND89370.1 - 2.7e-20 72.0 11.7 3.2e-20 71.8 8.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.1 KND89370.1 - 0.012 15.0 5.3 0.052 12.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) COG5 PF10392.4 KND89370.1 - 0.02 14.8 2.6 1 9.3 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Spc24 PF08286.6 KND89370.1 - 0.026 14.2 5.1 0.97 9.1 0.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Ndr PF03096.9 KND89370.1 - 0.03 12.8 0.1 0.03 12.8 0.1 1.2 1 1 0 1 1 1 0 Ndr family Spc7 PF08317.6 KND89370.1 - 0.034 12.8 7.0 0.04 12.5 4.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TcdA_TcdB PF12919.2 KND89370.1 - 0.039 12.4 0.8 0.049 12.1 0.5 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Prefoldin_3 PF13758.1 KND89370.1 - 0.045 13.5 5.6 0.062 13.0 3.8 1.2 1 0 0 1 1 1 0 Prefoldin subunit Prefoldin PF02996.12 KND89370.1 - 0.1 12.2 6.4 0.22 11.1 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit ADIP PF11559.3 KND89370.1 - 0.18 11.7 8.7 0.83 9.5 0.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YgaB PF14182.1 KND89370.1 - 0.24 11.6 12.5 0.17 12.1 3.2 2.3 2 0 0 2 2 2 0 YgaB-like protein DUF848 PF05852.6 KND89370.1 - 0.36 10.6 6.4 2.1 8.1 0.5 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2507 PF10702.4 KND89370.1 - 0.37 10.4 2.5 0.28 10.8 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2507) IncA PF04156.9 KND89370.1 - 0.43 10.1 14.2 9.8 5.7 9.8 2.0 1 1 0 1 1 1 0 IncA protein CENP-K PF11802.3 KND89370.1 - 0.67 9.1 5.0 1.1 8.4 3.4 1.3 1 1 0 1 1 1 0 Centromere-associated protein K Tropomyosin_1 PF12718.2 KND89370.1 - 0.8 9.5 9.0 3.1 7.6 0.9 2.1 2 0 0 2 2 2 0 Tropomyosin like CDC37_N PF03234.9 KND89370.1 - 0.89 9.8 5.7 1.1 9.5 4.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding COG2 PF06148.6 KND89370.1 - 1.2 8.9 6.2 4.6 7.1 0.5 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 KND89370.1 - 1.3 8.7 12.4 8.1 6.2 8.2 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 KND89370.1 - 1.3 8.5 16.4 3 7.3 2.6 3.1 2 2 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 KND89370.1 - 2.1 7.1 10.2 4.1 6.2 7.1 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KND89370.1 - 2.2 7.8 11.2 6 6.4 2.1 2.0 1 1 1 2 2 2 0 Mnd1 family Macoilin PF09726.4 KND89370.1 - 2.6 6.2 8.7 4.3 5.5 6.0 1.3 1 1 0 1 1 1 0 Transmembrane protein Rho_Binding PF08912.6 KND89370.1 - 3.1 8.1 8.0 7.7 6.9 0.9 2.3 2 0 0 2 2 2 0 Rho Binding DUF4200 PF13863.1 KND89370.1 - 6.5 6.7 11.4 6.1 6.8 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 KND89370.1 - 6.6 7.1 8.1 1.3e+02 2.9 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) AAA PF00004.24 KND89371.1 - 1.4e-41 141.7 0.0 3.6e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KND89371.1 - 8.5e-24 83.2 0.0 6e-23 80.4 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KND89371.1 - 3.2e-18 65.3 4.7 8.2e-18 64.0 2.9 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KND89371.1 - 5.9e-07 28.7 0.0 9.4e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KND89371.1 - 4.4e-06 27.5 0.1 2.6e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KND89371.1 - 2.1e-05 23.4 0.0 4.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KND89371.1 - 2.8e-05 23.6 0.0 6.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KND89371.1 - 2.8e-05 24.2 0.2 0.0032 17.5 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KND89371.1 - 3.3e-05 23.7 0.0 0.0001 22.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND89371.1 - 9.4e-05 22.4 0.0 0.0063 16.5 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KND89371.1 - 9.7e-05 22.4 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 KND89371.1 - 9.9e-05 22.0 0.0 0.00057 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KND89371.1 - 0.00015 20.7 0.1 0.00094 18.1 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF815) PrkA PF06798.7 KND89371.1 - 0.00065 19.0 1.0 0.0015 17.8 0.7 1.5 1 1 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_33 PF13671.1 KND89371.1 - 0.001 18.9 0.0 0.0034 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KND89371.1 - 0.0026 17.1 0.1 0.31 10.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 KND89371.1 - 0.0057 16.2 0.4 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KND89371.1 - 0.011 15.5 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KND89371.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KND89371.1 - 0.021 14.7 0.3 3.1 7.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KND89371.1 - 0.029 13.4 0.0 0.1 11.6 0.0 1.8 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KND89371.1 - 0.03 14.0 0.0 0.099 12.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 KND89371.1 - 0.031 13.4 0.0 0.083 12.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KND89371.1 - 0.051 12.8 0.4 0.11 11.6 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein NACHT PF05729.7 KND89371.1 - 0.07 12.7 0.0 0.83 9.2 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KND89371.1 - 0.12 12.4 0.1 0.5 10.4 0.0 2.1 2 0 0 2 2 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KND89371.1 - 0.13 11.8 0.3 1.2 8.7 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 KND89371.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA PF00004.24 KND89373.1 - 5.2e-30 104.3 0.0 7.5e-13 48.8 0.0 3.9 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND89373.1 - 5e-15 55.8 0.3 0.058 13.5 0.0 6.2 4 2 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KND89373.1 - 8.9e-13 49.1 0.1 0.00027 21.7 0.0 4.0 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KND89373.1 - 6.4e-10 39.3 1.4 0.026 14.5 0.0 5.9 5 1 1 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 KND89373.1 - 2.8e-09 36.8 0.2 0.074 12.7 0.0 4.3 4 1 0 4 4 3 3 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KND89373.1 - 5.3e-09 35.4 0.0 0.18 10.8 0.0 4.2 4 2 0 4 4 4 3 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KND89373.1 - 1.2e-08 35.2 0.7 0.023 15.0 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 KND89373.1 - 1.9e-08 33.9 0.7 0.043 13.5 0.0 3.9 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 KND89373.1 - 5.1e-07 29.0 0.0 0.12 11.5 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KND89373.1 - 1.3e-06 28.5 0.0 0.3 11.1 0.0 3.8 3 1 0 3 3 3 2 Sigma-54 interaction domain RNA_helicase PF00910.17 KND89373.1 - 1.5e-06 28.3 0.1 0.18 11.9 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 KND89373.1 - 2.7e-06 27.3 4.6 0.15 11.9 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 KND89373.1 - 6.8e-06 25.7 1.0 0.6 9.6 0.1 4.4 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KND89373.1 - 1.8e-05 24.7 3.3 0.39 10.6 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.1 KND89373.1 - 3.5e-05 23.4 2.7 0.72 9.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.22 KND89373.1 - 3.5e-05 24.1 0.1 0.15 12.3 0.0 3.2 3 0 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.21 KND89373.1 - 0.00026 20.5 1.6 1.2 8.5 0.0 5.3 5 1 0 5 5 5 1 Sigma-54 interaction domain Torsin PF06309.6 KND89373.1 - 0.00044 20.1 0.0 3.8 7.4 0.0 3.6 3 0 0 3 3 3 0 Torsin IstB_IS21 PF01695.12 KND89373.1 - 0.00061 19.2 0.3 5 6.5 0.0 3.7 4 0 0 4 4 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KND89373.1 - 0.00092 18.3 0.0 6.4 5.8 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin SKI PF01202.17 KND89373.1 - 0.0014 18.4 1.6 2.7 7.8 0.0 3.6 3 0 0 3 3 3 1 Shikimate kinase KTI12 PF08433.5 KND89373.1 - 0.0023 17.1 0.0 4 6.5 0.0 3.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 KND89373.1 - 0.0025 17.2 0.1 0.58 9.5 0.0 3.2 3 0 0 3 3 3 1 Thymidylate kinase MobB PF03205.9 KND89373.1 - 0.003 17.2 1.2 6.7 6.4 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 KND89373.1 - 0.0047 16.4 0.0 0.021 14.3 0.0 2.1 3 0 0 3 3 2 1 Virulence-associated protein E Viral_helicase1 PF01443.13 KND89373.1 - 0.0053 16.3 0.0 2.4 7.6 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KND89373.1 - 0.0064 16.0 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KND89373.1 - 0.009 15.4 0.5 2 7.7 0.0 4.0 3 1 1 4 4 4 1 AAA-like domain AAA_29 PF13555.1 KND89373.1 - 0.019 14.4 0.2 11 5.5 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KND89373.1 - 0.031 13.6 0.6 4.3 6.6 0.1 3.8 3 1 0 3 3 3 0 AAA domain PRK PF00485.13 KND89373.1 - 0.031 13.8 0.1 8.8 5.8 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF258 PF03193.11 KND89373.1 - 0.036 13.2 0.1 8.5 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 KND89373.1 - 0.037 12.9 1.5 11 4.8 0.0 4.2 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 KND89373.1 - 0.041 13.3 4.2 4 6.8 0.0 4.0 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 KND89373.1 - 0.043 13.4 0.1 16 5.1 0.0 3.5 3 0 0 3 3 3 0 Adenylylsulphate kinase UPF0079 PF02367.12 KND89373.1 - 0.065 12.8 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_32 PF13654.1 KND89373.1 - 0.074 11.6 0.7 0.21 10.2 0.0 2.0 3 0 0 3 3 2 0 AAA domain DEAD_2 PF06733.10 KND89373.1 - 0.11 11.8 0.0 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 DEAD_2 DUF4325 PF14213.1 KND89373.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) NACHT PF05729.7 KND89373.1 - 0.32 10.6 2.2 56 3.3 0.0 4.3 4 1 1 5 5 5 0 NACHT domain Myosin_head PF00063.16 KND89373.1 - 0.39 8.7 0.0 0.68 7.9 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) ResIII PF04851.10 KND89373.1 - 1.9 8.2 4.9 70 3.1 0.0 4.1 3 3 2 5 5 4 0 Type III restriction enzyme, res subunit Drc1-Sld2 PF11719.3 KND89374.1 - 5.1e-98 328.9 15.3 5.8e-98 328.7 10.6 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DNA_methylase PF00145.12 KND89375.1 - 3.1e-14 52.8 0.0 7.1e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 KND89375.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.8 1 1 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain DASH_Spc34 PF08657.5 KND89376.1 - 1.6e-43 149.3 0.0 1.2e-42 146.3 0.0 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 zf-RING_2 PF13639.1 KND89377.1 - 6.6e-09 35.4 14.7 1e-08 34.8 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND89377.1 - 1.1e-08 34.6 9.7 1.5e-08 34.1 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND89377.1 - 3.9e-07 29.9 14.8 6.1e-07 29.3 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND89377.1 - 2.3e-05 23.9 15.0 3.4e-05 23.4 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND89377.1 - 4.3e-05 23.5 8.8 8.2e-05 22.6 6.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KND89377.1 - 0.13 12.0 4.6 0.21 11.4 3.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KND89377.1 - 0.26 11.0 12.3 0.41 10.4 8.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KND89377.1 - 0.44 10.4 4.4 1.1 9.1 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 KND89377.1 - 3.5 7.3 6.9 5.5 6.7 4.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RrnaAD PF00398.15 KND89378.1 - 3.2e-08 32.9 0.0 5.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RrnaAD PF00398.15 KND89379.1 - 3.2e-08 32.9 0.0 5.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Glyco_transf_90 PF05686.7 KND89380.1 - 3.8e-17 62.0 0.8 5.4e-12 45.0 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 90 AHS2 PF02626.10 KND89381.1 - 1.2e-70 237.9 0.0 1.9e-70 237.2 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KND89381.1 - 4.9e-54 182.8 0.0 9.3e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KND89381.1 - 1.4e-32 112.8 0.0 2.8e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 KND89381.1 - 4.1e-32 110.3 0.0 2e-31 108.1 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KND89381.1 - 1.4e-27 95.9 0.0 3.5e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 KND89381.1 - 7.6e-11 41.5 3.5 2.3e-10 39.9 2.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KND89381.1 - 7.9e-11 42.0 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KND89381.1 - 1.5e-06 27.2 0.0 0.00026 19.8 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KND89381.1 - 3.2e-06 26.7 1.8 0.074 12.7 0.7 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KND89381.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KND89381.1 - 0.0041 16.4 0.0 0.0098 15.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 KND89381.1 - 0.0051 16.0 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Fungal_trans_2 PF11951.3 KND89382.1 - 5.2e-38 130.6 1.5 5.2e-38 130.6 1.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89382.1 - 4.3e-09 36.1 9.8 4.3e-09 36.1 6.8 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH PF01844.18 KND89382.1 - 0.0062 16.3 2.6 0.017 14.9 1.8 1.8 1 0 0 1 1 1 1 HNH endonuclease HAD_2 PF13419.1 KND89383.1 - 1.1e-08 35.5 0.0 1.2e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DMAP1 PF05499.7 KND89383.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF676 PF05057.9 KND89384.1 - 1.2e-05 24.7 0.2 2.5e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND89384.1 - 0.0013 18.4 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KND89384.1 - 0.0022 17.8 0.1 0.0054 16.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89384.1 - 0.0044 16.7 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KND89384.1 - 0.066 12.8 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Sec7 PF01369.15 KND89385.1 - 8.1e-40 136.5 0.0 1.6e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KND89385.1 - 9.8e-19 67.6 0.0 1.6e-17 63.7 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UNC-93 PF05978.11 KND89386.1 - 4.3e-08 32.8 5.2 4.3e-08 32.8 3.6 2.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KND89386.1 - 9.6e-08 31.1 38.2 9.6e-08 31.1 26.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Na_Ca_ex PF01699.19 KND89386.1 - 0.0058 16.2 4.6 0.1 12.1 0.4 3.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein LamB_YcsF PF03746.11 KND89387.1 - 6.3e-62 208.8 0.1 2.9e-45 154.2 0.0 2.0 1 1 0 2 2 2 2 LamB/YcsF family DUF3798 PF12683.2 KND89387.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Amidase PF01425.16 KND89388.1 - 2.2e-100 336.5 0.0 2.5e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF1524 PF07510.6 KND89389.1 - 5.8e-13 48.9 0.0 6.9e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Glyco_hydro_16 PF00722.16 KND89390.1 - 1.1e-28 99.7 2.0 1.7e-28 99.1 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 eIF3_N PF09440.5 KND89391.1 - 2.7e-42 144.0 2.1 4.7e-42 143.2 1.5 1.4 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KND89391.1 - 4.7e-11 42.9 0.0 1.3e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 KND89391.1 - 0.013 16.0 1.1 16 6.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc1 PF12859.2 KND89392.1 - 9.2e-28 96.5 0.1 2.6e-27 95.0 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KND89392.1 - 2.2e-06 27.5 0.3 0.055 13.7 0.1 4.9 4 0 0 4 4 4 2 Proteasome/cyclosome repeat ARID PF01388.16 KND89393.1 - 7.1e-20 70.6 0.0 7.1e-20 70.6 0.0 3.2 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain Zip PF02535.17 KND89393.1 - 2.2 7.2 3.7 3.5 6.5 2.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.6 KND89393.1 - 4.6 6.6 9.0 0.5 9.8 2.8 1.8 2 0 0 2 2 2 0 PPP4R2 Img2 PF05046.9 KND89394.1 - 2.9e-10 40.2 0.0 8.1e-10 38.7 0.0 1.7 1 1 1 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) GatB_N PF02934.10 KND89396.1 - 4e-102 340.9 0.0 5.1e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KND89396.1 - 3.7e-09 36.4 0.0 1.1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 GatB domain Y2_Tnp PF04986.8 KND89396.1 - 0.067 12.9 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative transposase HNOB PF07700.10 KND89396.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Heme NO binding Clathrin PF00637.15 KND89397.1 - 5.2e-21 74.7 1.2 7.3e-20 71.0 0.5 2.7 2 1 1 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 KND89397.1 - 0.00013 21.6 3.9 0.79 9.7 1.4 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 KND89397.1 - 0.00038 20.2 0.1 0.00086 19.0 0.1 1.7 1 0 0 1 1 1 1 Ring finger domain Daxx PF03344.10 KND89397.1 - 0.00061 18.4 4.4 0.0015 17.1 3.0 1.6 1 0 0 1 1 1 1 Daxx Family RXT2_N PF08595.6 KND89397.1 - 0.0014 18.4 7.0 0.0046 16.7 4.9 1.9 1 0 0 1 1 1 1 RXT2-like, N-terminal NBP1 PF08537.5 KND89397.1 - 0.025 13.7 0.2 0.052 12.7 0.2 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DNA_pol_phi PF04931.8 KND89397.1 - 0.034 11.9 12.7 0.052 11.3 8.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Vps39_1 PF10366.4 KND89397.1 - 0.05 13.6 1.7 0.48 10.4 0.3 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 KND89397.1 - 0.071 12.8 1.4 0.21 11.3 1.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 KND89397.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 CENP-B_dimeris PF09026.5 KND89397.1 - 0.64 10.2 23.0 0.11 12.7 11.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.7 KND89397.1 - 3.6 5.3 21.2 6.2 4.5 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 KND89397.1 - 8 6.1 6.1 28 4.3 4.2 1.9 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.7 KND89397.1 - 8.1 6.0 18.2 1.2 8.7 9.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF824 PF05688.6 KND89398.1 - 1.8 8.2 4.1 0.76 9.4 0.8 1.9 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) U3_assoc_6 PF08640.6 KND89399.1 - 2e-24 85.1 0.7 3.2e-23 81.2 0.1 2.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 KND89399.1 - 0.00013 20.9 1.6 0.00014 20.8 0.3 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KND89399.1 - 0.0047 17.4 0.2 2.7 8.8 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Glyco_hydro_47 PF01532.15 KND89399.1 - 0.09 11.4 0.0 0.24 10.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 47 Pkinase PF00069.20 KND89401.1 - 1.4e-29 103.0 0.0 2.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89401.1 - 1.6e-05 24.1 0.0 0.0015 17.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KND89401.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3435 PF11917.3 KND89402.1 - 5.6e-17 61.5 0.0 1.8e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) zf-met PF12874.2 KND89402.1 - 0.11 12.7 2.4 0.78 10.0 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.20 KND89403.1 - 1.7e-13 50.3 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89403.1 - 1.8e-06 27.2 0.0 4.3e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND89403.1 - 3.7e-05 23.5 0.0 9.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND89403.1 - 0.00031 20.1 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KND89403.1 - 0.00042 19.4 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND89403.1 - 0.0048 15.8 0.0 0.07 12.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 KND89403.1 - 0.0058 16.2 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 KND89403.1 - 0.13 11.0 0.1 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_12 PF13424.1 KND89404.1 - 8.7e-12 44.8 0.3 7.9e-05 22.5 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KND89404.1 - 1.2e-08 34.5 2.6 0.00059 19.6 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND89404.1 - 0.059 13.1 0.0 2.9 7.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FRQ PF09421.5 KND89405.1 - 0 1305.4 38.0 0 1304.8 26.3 1.1 1 0 0 1 1 1 1 Frequency clock protein Prenylcys_lyase PF07156.9 KND89405.1 - 5.9e-24 84.6 0.0 1.8e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KND89405.1 - 1.1e-09 38.2 0.0 3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KND89405.1 - 7.3e-08 31.8 0.3 5.2e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 KND89405.1 - 0.092 11.6 0.0 0.61 8.9 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Metalloenzyme PF01676.13 KND89406.1 - 1.3e-70 237.6 0.0 1.5e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KND89406.1 - 2.3e-69 233.1 0.0 3e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.18 KND89406.1 - 2.7e-07 30.0 0.0 5e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KND89406.1 - 6.3e-06 25.7 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AP_endonuc_2 PF01261.19 KND89406.1 - 0.004 16.4 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Med9 PF07544.8 KND89407.1 - 6.2e-22 77.1 0.7 5.9e-21 73.9 0.3 1.9 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 KND89407.1 - 0.036 13.5 0.1 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Med21 PF11221.3 KND89407.1 - 0.086 12.8 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex TBCC PF07986.7 KND89408.1 - 1.5e-32 111.4 0.1 2.4e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C NPV_P10 PF05531.7 KND89408.1 - 0.26 11.5 2.6 1.1 9.5 1.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Gpi1 PF05024.10 KND89409.1 - 7e-64 214.9 6.7 1.1e-63 214.2 4.6 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 KND89409.1 - 3.3e-26 90.9 2.3 6e-26 90.0 1.6 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KND89409.1 - 0.041 13.6 4.2 0.3 10.8 0.2 2.4 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like INTS5_N PF14837.1 KND89409.1 - 0.11 11.8 0.1 2.3 7.5 0.0 2.5 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus COX17 PF05051.8 KND89409.1 - 0.22 11.5 1.1 0.5 10.4 0.8 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_5 PF12695.2 KND89412.1 - 9.9e-15 54.5 0.1 1.4e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KND89412.1 - 2.6e-14 52.3 0.1 2.4e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KND89412.1 - 9.4e-07 28.9 0.2 9.4e-07 28.9 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KND89412.1 - 0.00044 19.2 0.0 0.08 11.8 0.0 2.4 2 1 0 2 2 2 2 Chlorophyllase enzyme Lipase_3 PF01764.20 KND89412.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Glycos_transf_2 PF00535.21 KND89413.1 - 2.9e-32 111.6 0.0 3.5e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KND89413.1 - 2.3e-13 50.4 0.0 4.2e-13 49.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KND89413.1 - 3.1e-07 29.7 0.0 4.1e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KND89413.1 - 1e-05 24.9 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KND89413.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 adh_short PF00106.20 KND89414.1 - 1.2e-34 119.5 1.7 1.9e-34 119.0 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND89414.1 - 3.5e-23 82.6 0.1 5.7e-22 78.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND89414.1 - 4.4e-17 62.3 0.4 6.2e-17 61.8 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KND89414.1 - 0.0085 15.7 1.5 0.021 14.5 1.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KND89414.1 - 0.037 13.8 0.4 0.068 13.0 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KND89414.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nop52 PF05997.7 KND89415.1 - 1.2e-41 142.5 0.0 1.4e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 NifW PF03206.9 KND89415.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW DUF2156 PF09924.4 KND89416.1 - 0.025 13.3 0.4 0.042 12.6 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) AATase PF07247.7 KND89417.1 - 1.1e-23 83.5 0.0 2.7e-23 82.2 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KND89417.1 - 3.6e-09 35.8 0.1 1.5e-07 30.5 0.1 2.1 2 0 0 2 2 2 2 Condensation domain DUF221 PF02714.10 KND89418.1 - 7.5e-94 314.2 14.6 1.2e-93 313.5 10.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 KND89418.1 - 1.4e-16 60.8 0.3 2.8e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 KND89418.1 - 1.1e-14 54.2 2.5 3.1e-14 52.8 1.7 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport TFIIB PF00382.14 KND89419.1 - 2.1e-30 104.3 1.0 2.5e-19 68.8 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KND89419.1 - 2.4e-21 75.7 0.7 2.4e-21 75.7 0.5 3.3 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KND89419.1 - 1.5e-05 24.5 0.5 0.0048 16.4 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Noc2 PF03715.8 KND89419.1 - 0.048 12.5 0.1 0.072 11.9 0.1 1.2 1 0 0 1 1 1 0 Noc2p family adh_short PF00106.20 KND89420.1 - 1.9e-20 73.4 0.2 2.5e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND89420.1 - 2.1e-05 24.2 2.3 0.00015 21.4 1.6 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND89420.1 - 6.9e-05 22.7 0.0 9.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KND89420.1 - 0.028 14.4 0.3 0.094 12.7 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding DUF2367 PF10164.4 KND89420.1 - 0.051 13.4 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) TcdA_TcdB_pore PF12920.2 KND89420.1 - 0.054 11.4 0.2 0.072 10.9 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Eno-Rase_NADH_b PF12242.3 KND89420.1 - 0.073 12.8 0.1 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 KND89421.1 - 9.3e-36 123.2 27.4 9.3e-36 123.2 19.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND89421.1 - 3.6e-08 32.4 16.5 5.2e-08 31.9 11.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.13 KND89422.1 - 1.5e-10 40.7 8.8 3.3e-10 39.7 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND89422.1 - 0.006 15.2 0.1 0.0091 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adeno_E1A PF02703.9 KND89422.1 - 0.32 10.3 4.3 1 8.7 1.4 2.0 2 0 0 2 2 2 0 Early E1A protein PP2C PF00481.16 KND89423.1 - 2.4e-30 105.7 0.0 4.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Abhydrolase_6 PF12697.2 KND89424.1 - 0.038 13.8 0.0 0.042 13.7 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.14 KND89425.1 - 2.9e-55 186.1 0.0 4e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND89425.1 - 1.1e-19 70.2 0.0 1.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KND89425.1 - 5.2e-08 32.8 0.0 1.4e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 KND89425.1 - 0.0019 18.1 1.5 0.65 9.8 0.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase AlaDh_PNT_C PF01262.16 KND89425.1 - 0.026 14.0 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 KND89425.1 - 0.099 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1338 PF07063.8 KND89426.1 - 2.8e-71 240.0 0.0 3.3e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) AA_permease PF00324.16 KND89427.1 - 1e-128 429.6 36.2 1.3e-128 429.3 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND89427.1 - 4.5e-31 107.8 37.3 6.7e-31 107.2 25.8 1.3 1 1 0 1 1 1 1 Amino acid permease Autophagy_act_C PF03987.10 KND89429.1 - 4.4e-13 49.2 0.3 1e-12 48.0 0.2 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.15 KND89430.1 - 2.2e-165 550.7 0.0 2.6e-165 550.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.16 KND89431.1 - 1e-139 465.9 38.4 1.3e-139 465.6 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND89431.1 - 1.5e-38 132.4 37.9 2e-38 132.0 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease SnoaL PF07366.7 KND89432.1 - 0.089 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PrpF PF04303.8 KND89433.1 - 4.7e-93 311.8 7.3 4.9e-87 292.0 2.1 2.0 2 0 0 2 2 2 2 PrpF protein Fungal_trans PF04082.13 KND89434.1 - 1.2e-27 96.4 0.8 1.8e-27 95.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89434.1 - 5.5e-08 32.6 7.8 1e-07 31.7 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 KND89435.1 - 0.00018 21.0 0.1 0.00038 20.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KND89435.1 - 0.0007 19.2 0.3 0.0007 19.2 0.2 2.2 2 0 0 2 2 2 1 F-box-like Mito_carr PF00153.22 KND89436.1 - 7.9e-58 192.1 8.0 7.6e-22 76.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 KND89437.1 - 1.9e-29 102.5 25.1 1.9e-29 102.5 17.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 KND89437.1 - 0.029 13.8 0.0 0.15 11.5 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Ribonuc_L-PSP PF01042.16 KND89438.1 - 3.3e-41 139.8 0.0 4.4e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Tryp_alpha_amyl PF00234.17 KND89438.1 - 0.075 13.2 0.7 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family WD40 PF00400.27 KND89439.1 - 5e-25 86.4 9.5 8e-08 31.8 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Rax2 PF12768.2 KND89439.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Gmad1 PF10647.4 KND89439.1 - 0.077 12.3 0.2 4.3 6.6 0.0 2.5 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain RRM_5 PF13893.1 KND89440.1 - 1.1e-11 44.3 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND89440.1 - 2.8e-08 33.2 0.0 8e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND89440.1 - 5.7e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KND89441.1 - 1.3e-52 178.5 0.1 1.8e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89441.1 - 2.1e-26 92.5 0.1 3.2e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND89441.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KND89442.1 - 2.7e-59 200.4 0.0 3.6e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89442.1 - 6.8e-31 107.2 0.0 8.8e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND89442.1 - 0.00017 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND89442.1 - 0.00024 20.1 0.0 0.0011 17.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND89442.1 - 0.0017 18.1 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND89442.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UL11 PF11094.3 KND89442.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_ser-thr_kin PF05445.6 KND89442.1 - 0.027 13.2 0.0 0.057 12.2 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 KND89442.1 - 0.17 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Auxin_inducible PF02519.9 KND89443.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Auxin responsive protein ADP_ribosyl_GH PF03747.9 KND89444.1 - 3e-64 217.5 0.2 4.1e-64 217.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.10 KND89444.1 - 1.4 8.6 4.8 1.4 8.6 0.3 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ferric_reduct PF01794.14 KND89445.1 - 8.6e-21 74.3 17.1 2.1e-20 73.0 11.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KND89445.1 - 1.2e-08 34.7 0.2 2.3e-06 27.4 0.2 2.7 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KND89445.1 - 1.8e-06 27.9 0.1 0.026 14.4 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KND89445.1 - 6.7e-06 26.6 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1352 PF07086.7 KND89445.1 - 5.2 6.6 10.5 0.37 10.3 3.4 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) CDC45 PF02724.9 KND89446.1 - 2.9 5.7 7.8 4.2 5.2 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 KND89446.1 - 3.6 6.5 7.5 4.9 6.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 KND89446.1 - 4.1 5.1 8.9 5.7 4.7 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 KND89446.1 - 9.2 5.4 12.2 14 4.8 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein HlyIII PF03006.15 KND89447.1 - 3.1e-60 203.3 15.8 3.7e-60 203.0 11.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 KND89447.1 - 0.19 11.6 4.5 0.061 13.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) PRA1 PF03208.14 KND89447.1 - 5.2 6.4 6.4 1.4 8.2 0.4 2.7 3 1 0 3 3 3 0 PRA1 family protein TMA7 PF09072.5 KND89448.1 - 1.4e-16 60.6 16.6 1.7e-08 34.8 3.4 2.2 2 0 0 2 2 2 2 Translation machinery associated TMA7 Apc3 PF12895.2 KND89449.1 - 0.0072 16.4 0.2 0.017 15.2 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.8 KND89449.1 - 0.054 13.0 0.1 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 HemY protein N-terminus TPR_4 PF07721.9 KND89449.1 - 0.21 12.0 0.3 0.21 12.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat 2-oxoacid_dh PF00198.18 KND89452.1 - 3.1e-74 249.1 0.0 5.2e-74 248.4 0.0 1.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KND89452.1 - 4.4e-17 61.4 0.1 8.2e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KND89452.1 - 8.6e-12 44.4 0.2 2.6e-11 42.9 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain BEX PF04538.7 KND89452.1 - 0.036 14.2 0.2 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Brain expressed X-linked like family AAA_17 PF13207.1 KND89453.1 - 2e-12 47.9 0.1 3.9e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KND89453.1 - 4.4e-12 46.1 0.0 5.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KND89453.1 - 6.2e-10 39.1 0.0 8.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND89453.1 - 7.9e-09 35.9 0.0 2.4e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KND89453.1 - 1.9e-05 24.8 0.0 5.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KND89453.1 - 8e-05 21.5 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KND89453.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KND89453.1 - 0.00011 21.8 0.0 0.00055 19.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Cytidylate_kin2 PF13189.1 KND89453.1 - 0.00018 21.4 0.0 0.006 16.5 0.0 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.1 KND89453.1 - 0.00054 19.9 0.0 0.00073 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND89453.1 - 0.00087 19.3 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain CoaE PF01121.15 KND89453.1 - 0.002 17.5 0.0 0.0091 15.4 0.0 1.9 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_5 PF07728.9 KND89453.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KND89453.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PRK PF00485.13 KND89453.1 - 0.0025 17.3 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 KND89453.1 - 0.0032 17.6 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 KND89453.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 KND89453.1 - 0.0087 15.4 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Mg_chelatase PF01078.16 KND89453.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KND89453.1 - 0.014 14.9 0.1 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND89453.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 KND89453.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KND89453.1 - 0.033 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 KND89453.1 - 0.033 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RuvB_N PF05496.7 KND89453.1 - 0.038 13.0 0.1 0.098 11.6 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KND89453.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KND89453.1 - 0.043 13.4 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 KND89453.1 - 0.055 13.7 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 KND89453.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-H2C2_2 PF13465.1 KND89454.1 - 4.5e-25 86.6 29.7 2e-07 30.9 0.5 7.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 KND89454.1 - 3.6e-19 67.8 46.4 0.00013 22.1 2.4 8.2 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND89454.1 - 1.8e-11 43.5 44.6 0.013 15.8 1.2 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND89454.1 - 6.1e-06 26.2 23.3 0.076 13.1 0.5 6.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND89454.1 - 0.00012 21.8 7.8 0.0019 18.0 0.3 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-BED PF02892.10 KND89454.1 - 0.25 11.1 21.6 3 7.6 0.3 4.7 1 1 3 4 4 4 0 BED zinc finger zf-met PF12874.2 KND89454.1 - 4.1 7.7 29.0 1.1 9.5 0.9 6.4 7 0 0 7 7 7 0 Zinc-finger of C2H2 type V-SNARE_C PF12352.3 KND89455.1 - 1.8e-13 50.3 0.5 1.8e-13 50.3 0.4 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FTCD_C PF04961.7 KND89455.1 - 0.098 12.0 1.3 0.44 9.9 0.3 2.0 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF2450 PF10475.4 KND89455.1 - 0.39 9.5 2.2 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF4164 PF13747.1 KND89455.1 - 6.6 6.9 12.9 3.6 7.7 2.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Ribosomal_L29 PF00831.18 KND89457.1 - 4.9e-18 64.5 1.7 4.9e-18 64.5 1.2 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein DUF1192 PF06698.6 KND89457.1 - 0.055 13.2 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ribosomal_S9 PF00380.14 KND89457.1 - 0.17 12.1 2.5 0.21 11.8 1.7 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 HCNGP PF07818.8 KND89458.1 - 1.4e-24 85.9 0.5 2.1e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 HCNGP-like protein Menin PF05053.8 KND89458.1 - 0.59 8.2 5.6 2.3 6.2 4.0 1.7 2 0 0 2 2 2 0 Menin DUF605 PF04652.11 KND89458.1 - 2.7 7.2 19.7 3.6 6.8 13.7 1.1 1 0 0 1 1 1 0 Vta1 like TEX19 PF15553.1 KND89458.1 - 3.3 7.5 5.5 6.1 6.6 3.8 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DEAD PF00270.24 KND89459.1 - 4.7e-44 149.8 0.0 8.7e-44 148.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND89459.1 - 3.8e-24 84.3 0.0 1.1e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_M49 PF03571.10 KND89460.1 - 1.4e-228 759.4 0.0 1.7e-228 759.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Ribosomal_L6e PF01159.14 KND89461.1 - 1.1e-36 125.4 0.3 1.1e-36 125.4 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.24 KND89461.1 - 0.34 10.6 1.4 0.64 9.8 0.1 2.2 2 1 0 2 2 2 0 KOW motif BTB PF00651.26 KND89462.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain EBV-NA3 PF05009.7 KND89463.1 - 0.021 14.0 1.0 0.04 13.1 0.7 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) zf-C2H2_jaz PF12171.3 KND89463.1 - 0.23 11.6 1.9 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ppx-GppA PF02541.11 KND89464.1 - 8.3e-25 87.5 0.0 1.8e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Ppx/GppA phosphatase family F-box-like PF12937.2 KND89465.1 - 0.00067 19.3 1.0 0.0024 17.5 0.7 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KND89465.1 - 0.055 13.1 0.4 0.055 13.1 0.3 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.28 KND89465.1 - 0.064 12.9 5.2 0.041 13.5 0.9 2.7 2 1 0 2 2 2 0 F-box domain LRR_6 PF13516.1 KND89465.1 - 0.23 11.6 5.2 5.9 7.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat IU_nuc_hydro PF01156.14 KND89466.1 - 4.1e-83 279.1 0.1 4.7e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 KND89467.1 - 1.5e-08 34.1 9.8 3e-08 33.1 6.8 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region DUF2924 PF11149.3 KND89467.1 - 0.019 15.0 0.4 0.019 15.0 0.3 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2924) MFS_2 PF13347.1 KND89468.1 - 3.7e-09 35.4 9.8 3.7e-09 35.4 6.8 2.5 3 1 0 3 3 3 1 MFS/sugar transport protein Pkr1 PF08636.5 KND89469.1 - 9e-34 115.3 5.7 1.2e-33 115.0 3.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 KND89469.1 - 0.061 11.6 0.0 0.072 11.4 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family FAM176 PF14851.1 KND89469.1 - 0.076 12.6 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 FAM176 family PRA1 PF03208.14 KND89469.1 - 0.095 12.0 0.1 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 PRA1 family protein RhoGEF PF00621.15 KND89470.1 - 1.8e-32 112.6 0.2 3.3e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KND89470.1 - 1.3e-10 41.2 0.1 3.2e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 BAR domain DUF4219 PF13961.1 KND89470.1 - 0.48 9.9 0.2 0.85 9.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) MBOAT_2 PF13813.1 KND89471.1 - 3.9e-14 52.4 6.3 1.1e-13 51.0 4.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Zn_clus PF00172.13 KND89472.1 - 7.8e-06 25.7 7.7 2.7e-05 23.9 5.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 KND89474.1 - 1.9e-62 207.0 1.4 4.4e-21 74.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KND89475.1 - 5.3e-60 199.1 0.1 6e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AICARFT_IMPCHas PF01808.13 KND89476.1 - 1.5e-112 375.7 0.0 2e-112 375.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KND89476.1 - 8.5e-24 83.3 0.0 1.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF4243 PF14027.1 KND89477.1 - 1.5e-74 251.4 0.8 2.6e-74 250.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Rad17 PF03215.10 KND89477.1 - 2.9e-54 184.6 0.0 4.3e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KND89477.1 - 0.0085 16.3 0.0 0.032 14.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KND89477.1 - 0.0087 15.6 0.0 0.03 13.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KND89477.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 KND89477.1 - 0.018 15.8 0.1 0.085 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KND89477.1 - 0.019 15.1 0.1 0.06 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KND89477.1 - 0.02 14.6 0.1 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KND89477.1 - 0.042 12.9 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SCRG1 PF15224.1 KND89477.1 - 0.31 10.8 0.7 0.78 9.5 0.0 1.9 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Herpes_Helicase PF02689.9 KND89477.1 - 0.43 8.2 0.0 0.65 7.6 0.0 1.1 1 0 0 1 1 1 0 Helicase TAFII55_N PF04658.8 KND89479.1 - 1.1e-48 164.7 0.5 3.3e-48 163.2 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF3074 PF11274.3 KND89480.1 - 1.5e-39 135.4 0.7 4.7e-39 133.9 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) DUF842 PF05811.8 KND89480.1 - 0.041 13.3 0.1 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) p450 PF00067.17 KND89481.1 - 5.8e-72 242.6 0.0 7.4e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YjgP_YjgQ PF03739.9 KND89481.1 - 0.29 9.8 1.2 0.44 9.2 0.8 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Stk19 PF10494.4 KND89482.1 - 7.7e-49 166.3 0.0 1.1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Herpes_IE68 PF02479.11 KND89483.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus immediate early protein Adeno_terminal PF02459.10 KND89483.1 - 0.088 10.9 0.6 0.11 10.6 0.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SAE2 PF08573.5 KND89483.1 - 0.24 12.1 2.5 0.41 11.3 1.7 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Kinesin PF00225.18 KND89485.1 - 7.4e-95 317.4 0.0 1.4e-94 316.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain RRM_1 PF00076.17 KND89487.1 - 2e-37 126.6 0.9 1.6e-18 66.1 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND89487.1 - 9.1e-25 86.4 0.0 4.8e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND89487.1 - 8.2e-12 44.7 0.0 8.8e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 KND89487.1 - 0.15 11.3 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated MIP-T3 PF10243.4 KND89487.1 - 0.28 9.6 47.1 0.33 9.3 32.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Telomerase_RBD PF12009.3 KND89489.1 - 1.6e-42 144.6 0.0 3e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KND89489.1 - 2.1e-18 66.4 0.1 1.2e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_Gp111 PF07410.6 KND89489.1 - 0.24 11.5 0.0 0.62 10.2 0.0 1.6 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein PNP_UDP_1 PF01048.15 KND89490.1 - 6.1e-12 45.0 0.0 5.4e-11 41.9 0.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily OrfB_Zn_ribbon PF07282.6 KND89490.1 - 0.00066 19.2 0.2 0.0017 17.9 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Annexin PF00191.15 KND89492.1 - 4.8e-58 192.9 3.8 1.6e-15 56.7 0.0 4.9 4 2 0 4 4 4 4 Annexin Lipase_GDSL_2 PF13472.1 KND89493.1 - 1.1e-17 64.7 0.0 1.4e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KND89493.1 - 4.9e-09 36.3 0.0 1.1e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HTH_AsnC-type PF13404.1 KND89493.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain AfsA PF03756.8 KND89494.1 - 0.067 12.9 0.1 0.08 12.6 0.1 1.1 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain PCI PF01399.22 KND89495.1 - 4.3e-12 46.2 0.0 2.2e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 KND89495.1 - 0.0011 18.3 0.4 0.0011 18.3 0.3 2.0 2 1 1 3 3 3 1 26S proteasome subunit RPN7 zf-C2H2 PF00096.21 KND89496.1 - 0.0011 19.1 4.0 0.23 11.8 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND89496.1 - 0.0014 18.8 4.9 0.24 11.8 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND89496.1 - 0.013 15.7 0.6 0.032 14.5 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 KND89496.1 - 0.03 13.5 0.3 0.05 12.8 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 KND89496.1 - 0.041 13.8 2.5 4.7 7.2 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Cullin PF00888.17 KND89497.1 - 1.1e-49 169.5 0.0 2.2e-49 168.5 0.0 1.4 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 KND89497.1 - 9.6e-20 70.6 0.0 1.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DivIC PF04977.10 KND89498.1 - 1.7 8.2 9.1 1 8.8 0.5 3.5 2 1 1 3 3 3 0 Septum formation initiator Reo_sigmaC PF04582.7 KND89498.1 - 2.1 7.4 3.0 4.5 6.3 2.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PHB_acc PF05233.8 KND89499.1 - 0.032 13.9 0.5 0.089 12.5 0.4 1.8 1 0 0 1 1 1 0 PHB accumulation regulatory domain FAINT PF04385.10 KND89501.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Fungal_trans_2 PF11951.3 KND89502.1 - 5.1e-14 51.6 0.3 7.4e-14 51.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89502.1 - 3.3e-06 26.8 15.8 6.3e-06 26.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KND89503.1 - 6.6e-19 68.4 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND89503.1 - 6.4e-05 23.7 0.0 0.00025 21.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND89503.1 - 7e-05 22.5 0.0 0.00063 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND89503.1 - 0.00014 21.9 0.1 0.0013 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KND89503.1 - 0.00065 19.3 0.2 0.0015 18.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KND89503.1 - 0.00071 19.6 0.1 0.002 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 KND89503.1 - 0.00086 18.8 0.0 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_18 PF13238.1 KND89503.1 - 0.0011 19.2 0.0 0.0046 17.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 KND89503.1 - 0.0016 17.5 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KND89503.1 - 0.0061 16.4 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KND89503.1 - 0.019 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 KND89503.1 - 0.031 13.1 0.0 0.73 8.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 KND89503.1 - 0.035 14.0 0.1 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KND89503.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KND89503.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KND89503.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KND89503.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND89503.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 KND89503.1 - 0.087 12.2 4.1 0.18 11.2 2.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aconitase_B_N PF11791.3 KND89503.1 - 0.089 12.6 0.2 0.22 11.3 0.0 1.7 2 0 0 2 2 1 0 Aconitate B N-terminal domain AAA_11 PF13086.1 KND89503.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain BTB PF00651.26 KND89504.1 - 2.6e-14 53.1 0.1 5.6e-14 52.0 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain Beta-lactamase PF00144.19 KND89505.1 - 6.8e-30 104.2 2.5 1.2e-29 103.4 1.8 1.3 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 KND89506.1 - 2.2e-07 29.8 0.0 2.4e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89506.1 - 1.1e-06 28.4 8.0 2.8e-06 27.1 5.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KND89507.1 - 1.3e-94 310.6 21.2 4.8e-17 62.0 0.0 5.9 1 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KND89507.1 - 8.4e-66 214.6 33.9 1e-05 25.1 0.1 13.4 12 1 1 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KND89507.1 - 4.8e-49 163.9 10.3 3.5e-08 33.7 0.1 11.9 4 3 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89507.1 - 1.2e-41 136.5 16.0 0.0091 16.1 0.1 13.0 12 1 1 13 13 13 9 Ankyrin repeat Ank_5 PF13857.1 KND89507.1 - 2.3e-29 100.7 24.3 0.0002 21.5 0.2 8.2 3 2 4 8 8 8 8 Ankyrin repeats (many copies) NACHT PF05729.7 KND89507.1 - 3e-15 56.2 0.1 5.2e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KND89507.1 - 3e-06 27.1 0.1 0.0002 21.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND89507.1 - 3.8e-06 27.0 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KND89507.1 - 1e-05 25.7 0.0 3.4e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND89507.1 - 1.4e-05 25.2 0.0 3.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KND89507.1 - 2.9e-05 23.8 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 KND89507.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RVP PF00077.15 KND89507.1 - 0.0021 17.9 6.8 27 4.7 0.0 7.7 5 3 2 9 9 9 0 Retroviral aspartyl protease RNA_helicase PF00910.17 KND89507.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF4235 PF14019.1 KND89507.1 - 0.045 13.6 4.6 1.2e+02 2.6 0.1 6.4 7 1 1 8 8 8 0 Protein of unknown function (DUF4235) Nitro_FeMo-Co PF02579.12 KND89507.1 - 1.1 9.3 14.8 60 3.8 0.0 7.1 3 2 5 8 8 8 0 Dinitrogenase iron-molybdenum cofactor Ank PF00023.25 KND89508.1 - 0.0022 17.7 0.1 0.0064 16.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KND89508.1 - 0.015 15.8 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND89508.1 - 0.057 13.7 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RabGAP-TBC PF00566.13 KND89509.1 - 2.2e-34 118.7 0.0 1.8e-17 63.5 0.0 3.1 3 0 0 3 3 3 3 Rab-GTPase-TBC domain PAS_7 PF12860.2 KND89509.1 - 0.18 11.7 0.4 0.45 10.5 0.2 1.6 1 0 0 1 1 1 0 PAS fold UQ_con PF00179.21 KND89510.1 - 2.6e-34 117.6 0.1 2.9e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND89510.1 - 2.9e-07 30.3 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND89510.1 - 0.15 11.9 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RWD domain Filament PF00038.16 KND89512.1 - 0.23 10.9 82.1 0.013 15.0 7.3 6.9 5 2 1 6 6 6 0 Intermediate filament protein MtrB PF05440.7 KND89512.1 - 1 9.4 3.4 9.3 6.3 0.1 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Reo_sigmaC PF04582.7 KND89512.1 - 4 6.5 32.7 0.2 10.8 2.4 4.8 5 0 0 5 5 5 0 Reovirus sigma C capsid protein Med16 PF11635.3 KND89513.1 - 9.6e-110 367.7 0.0 1.2e-109 367.3 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ku_C PF03730.9 KND89513.1 - 0.15 12.6 0.1 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm FAD-oxidase_C PF02913.14 KND89514.1 - 1.7e-57 194.5 0.1 2.5e-57 194.0 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KND89514.1 - 3.8e-37 126.8 0.0 7.8e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ANF_receptor PF01094.23 KND89514.1 - 0.0021 16.9 0.2 0.0033 16.2 0.2 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DNA_pol_B_palm PF14792.1 KND89515.1 - 1.1e-32 112.3 0.0 2.2e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KND89515.1 - 2.7e-21 75.0 0.1 1.3e-20 72.8 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KND89515.1 - 5.7e-21 73.8 0.2 1.6e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KND89515.1 - 1.1e-15 57.6 2.5 1.9e-15 56.8 0.1 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KND89515.1 - 0.009 16.3 0.1 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 KND89515.1 - 0.016 15.3 0.1 0.3 11.3 0.0 2.5 1 1 2 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.2 KND89515.1 - 0.071 13.0 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Brix PF04427.13 KND89516.1 - 2.9e-57 193.4 0.0 3.9e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF2500 PF10694.4 KND89516.1 - 0.16 11.9 2.6 0.35 10.8 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) ABC_tran PF00005.22 KND89517.1 - 2.3e-51 173.7 0.0 2.9e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND89517.1 - 2.2e-27 96.2 11.7 2.2e-27 96.2 8.1 3.4 4 0 0 4 4 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 KND89517.1 - 1.8e-11 44.5 0.1 0.056 13.4 0.1 5.0 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 KND89517.1 - 1.2e-09 37.7 2.1 0.18 11.0 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND89517.1 - 2.2e-09 36.7 0.5 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KND89517.1 - 3.4e-08 32.8 0.1 0.0025 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND89517.1 - 4.5e-08 33.3 0.0 0.0013 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KND89517.1 - 1.3e-06 28.5 0.5 0.25 11.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KND89517.1 - 1.4e-06 29.1 0.1 0.036 14.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND89517.1 - 2.6e-06 26.9 0.0 0.015 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KND89517.1 - 3.2e-06 27.3 0.7 2.2 8.4 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KND89517.1 - 4.6e-06 26.5 0.1 0.027 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 KND89517.1 - 4.9e-06 27.0 0.2 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KND89517.1 - 6.3e-06 26.6 0.1 0.0062 17.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 KND89517.1 - 1.8e-05 24.5 0.0 0.14 11.8 0.0 2.8 3 0 0 3 3 2 2 Archaeal ATPase AAA_18 PF13238.1 KND89517.1 - 3.7e-05 24.0 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KND89517.1 - 4.6e-05 22.4 0.0 0.28 10.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 KND89517.1 - 6.4e-05 22.8 0.3 0.19 11.5 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_10 PF12846.2 KND89517.1 - 0.00011 21.7 1.9 0.031 13.7 0.3 2.7 3 0 0 3 3 2 1 AAA-like domain AAA_33 PF13671.1 KND89517.1 - 0.00014 21.8 0.0 0.3 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KND89517.1 - 0.00015 21.4 0.3 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KND89517.1 - 0.00025 20.5 0.0 0.098 12.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 KND89517.1 - 0.00053 19.6 0.1 0.85 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KND89517.1 - 0.001 18.9 4.8 0.061 13.1 0.0 2.6 3 0 0 3 3 2 1 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 KND89517.1 - 0.0012 18.4 0.5 2.6 7.5 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 KND89517.1 - 0.0021 17.1 0.2 0.91 8.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KND89517.1 - 0.0033 17.5 0.1 4 7.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATP-synt_ab PF00006.20 KND89517.1 - 0.0039 16.7 0.0 0.99 8.8 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KND89517.1 - 0.0047 16.6 0.4 0.67 9.6 0.0 2.8 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.17 KND89517.1 - 0.0075 15.1 0.0 0.45 9.3 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Adeno_IVa2 PF02456.10 KND89517.1 - 0.0093 14.6 0.0 0.89 8.1 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF815 PF05673.8 KND89517.1 - 0.011 14.7 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 KND89517.1 - 0.012 15.0 1.3 0.81 9.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KND89517.1 - 0.013 14.9 0.0 0.76 9.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein UPF0079 PF02367.12 KND89517.1 - 0.017 14.7 0.2 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 KND89517.1 - 0.026 14.4 2.0 7.6 6.5 0.0 3.2 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.4 KND89517.1 - 0.028 13.0 0.2 6.2 5.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 KND89517.1 - 0.049 13.1 0.2 5.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 KND89517.1 - 0.097 12.3 0.1 23 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KND89517.1 - 0.13 12.1 0.1 16 5.3 0.1 3.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KND89517.1 - 0.15 10.8 0.1 9 4.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Septin PF00735.13 KND89517.1 - 0.19 10.6 0.2 10 5.0 0.1 2.2 2 0 0 2 2 2 0 Septin Guanylate_kin PF00625.16 KND89517.1 - 0.2 11.1 0.2 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase PduV-EutP PF10662.4 KND89517.1 - 0.23 10.9 0.9 6 6.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KND89517.1 - 0.23 10.8 0.0 18 4.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DEAD PF00270.24 KND89517.1 - 0.31 10.5 0.8 3.2 7.2 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KND89518.1 - 2.7e-12 46.9 0.0 6.9e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND89518.1 - 8.6e-10 38.8 0.0 2.8e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KND89518.1 - 3.5e-08 33.7 0.0 1.4e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 KND89518.1 - 0.00019 21.1 0.0 0.00086 18.9 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal AAA_19 PF13245.1 KND89518.1 - 0.011 15.5 0.0 0.044 13.5 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 KND89518.1 - 0.012 14.5 0.0 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KND89518.1 - 0.057 12.9 1.0 0.66 9.4 0.0 2.7 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KND89518.1 - 0.073 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND89518.1 - 0.11 12.7 0.2 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KND89518.1 - 0.12 12.0 0.0 0.72 9.4 0.0 2.3 3 0 0 3 3 3 0 Archaeal ATPase TspO_MBR PF03073.10 KND89519.1 - 7e-42 142.4 4.8 8.2e-42 142.2 3.3 1.1 1 0 0 1 1 1 1 TspO/MBR family Yip1 PF04893.12 KND89519.1 - 1.1 8.7 6.4 0.52 9.7 2.6 1.8 1 1 0 1 1 1 0 Yip1 domain HSCB_C PF07743.8 KND89520.1 - 5.9e-14 52.2 0.7 1.1e-13 51.4 0.5 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KND89520.1 - 1e-09 37.9 0.4 2.8e-09 36.5 0.3 1.7 2 0 0 2 2 2 1 DnaJ domain Arrestin_N PF00339.24 KND89521.1 - 1.5e-17 63.7 0.0 1.2e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain WSC PF01822.14 KND89522.1 - 5.4e-18 64.6 8.1 7.5e-18 64.2 5.6 1.2 1 0 0 1 1 1 1 WSC domain IMS PF00817.15 KND89523.1 - 1.5e-39 135.1 0.0 2.8e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KND89523.1 - 6.7e-17 61.6 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KND89523.1 - 5.1e-14 52.0 3.2 2.5e-06 27.3 0.2 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KND89523.1 - 6.1e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 KND89523.1 - 8.7e-05 22.3 0.0 0.00061 19.6 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.1 KND89523.1 - 0.001 19.1 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF1805 PF08827.6 KND89523.1 - 0.094 12.5 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) PTCB-BRCT PF12738.2 KND89523.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain SHR3_chaperone PF08229.6 KND89524.1 - 1.5e-70 236.1 0.0 1.7e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF3712 PF12505.3 KND89525.1 - 1.3e-19 70.4 2.5 1.3e-19 70.4 1.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Prominin PF05478.6 KND89525.1 - 0.013 13.0 0.1 0.021 12.4 0.1 1.2 1 0 0 1 1 1 0 Prominin Baculo_11_kDa PF06143.6 KND89525.1 - 0.03 13.6 0.1 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family FMN_dh PF01070.13 KND89526.1 - 1.5e-92 310.2 0.0 1.8e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KND89526.1 - 9.8e-21 73.3 0.0 2.4e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KND89526.1 - 6.2e-07 28.6 0.0 0.00085 18.3 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KND89526.1 - 5.5e-06 25.5 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 KND89526.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein WH2 PF02205.15 KND89527.1 - 5.1e-09 35.4 0.2 5.1e-09 35.4 0.1 2.4 3 0 0 3 3 3 1 WH2 motif DUF3989 PF13150.1 KND89528.1 - 0.47 9.9 4.4 0.2 11.1 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Ribosomal_L37 PF08561.5 KND89529.1 - 2.4e-29 100.7 8.1 1.6e-27 94.8 5.6 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 adh_short PF00106.20 KND89531.1 - 8e-11 42.1 0.7 3.5e-10 40.0 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND89531.1 - 0.00038 20.1 0.2 0.00059 19.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND89531.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND89531.1 - 0.11 11.3 0.0 0.46 9.3 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.1 KND89531.1 - 0.18 11.7 0.9 0.71 9.8 0.6 2.0 1 1 0 1 1 1 0 NADH(P)-binding Abhydrolase_6 PF12697.2 KND89533.1 - 6.4e-31 107.9 0.1 9.8e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND89533.1 - 1.6e-15 57.3 0.1 3.9e-15 56.0 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND89533.1 - 1.5e-14 53.9 0.3 4.7e-14 52.3 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND89533.1 - 0.0002 21.1 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KND89533.1 - 0.00029 19.4 0.0 0.00055 18.5 0.0 1.4 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.2 KND89533.1 - 0.00089 18.2 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KND89533.1 - 0.0015 17.7 0.5 1.1 8.4 0.2 2.9 2 1 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.8 KND89533.1 - 0.0042 16.7 0.3 0.007 15.9 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KND89533.1 - 0.067 12.2 0.4 0.33 9.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.6 KND89533.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF2048 PF09752.4 KND89533.1 - 0.14 10.9 0.3 0.35 9.6 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) BNR PF02012.15 KND89535.1 - 2e-12 44.9 39.4 0.76 9.8 0.0 12.1 11 0 0 11 11 11 7 BNR/Asp-box repeat PSII_BNR PF14870.1 KND89535.1 - 2.9e-05 23.2 0.4 0.3 10.0 0.0 5.6 5 1 1 6 6 6 1 Photosynthesis system II assembly factor YCF48 DctQ PF04290.7 KND89535.1 - 0.029 14.1 0.8 0.068 12.9 0.5 1.5 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component p450 PF00067.17 KND89536.1 - 3.5e-51 174.1 0.0 1e-35 123.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Vezatin PF12632.2 KND89537.1 - 1.7e-55 187.8 0.2 3.3e-55 186.9 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes CD99L2 PF12301.3 KND89537.1 - 0.038 13.6 0.2 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF4231 PF14015.1 KND89537.1 - 0.05 13.5 2.1 0.13 12.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4131 PF13567.1 KND89537.1 - 0.078 12.3 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PCNA_N PF00705.13 KND89538.1 - 5.4e-56 187.5 5.1 1.2e-55 186.3 3.1 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KND89538.1 - 3.9e-50 169.0 0.1 1.2e-49 167.5 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KND89538.1 - 2.4e-11 43.2 0.1 2.8e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KND89538.1 - 1.4e-06 27.5 0.3 0.00022 20.2 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein DNA_pol3_beta_3 PF02768.10 KND89538.1 - 0.0095 15.4 0.4 0.11 12.0 0.1 2.6 2 2 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain Phos_pyr_kin PF08543.7 KND89539.1 - 1e-12 47.7 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KND89539.1 - 4.8e-12 45.6 0.2 2.6e-08 33.3 0.0 2.6 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Tim17 PF02466.14 KND89541.1 - 6.5e-21 74.6 0.0 1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HECT_2 PF09814.4 KND89544.1 - 5e-53 180.0 0.0 7.8e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.18 KND89544.1 - 2.2e-31 108.7 0.0 2.5e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 KND89544.1 - 3.6e-05 23.3 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND89544.1 - 0.0043 16.8 0.1 0.0092 15.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-ISL3 PF14690.1 KND89544.1 - 0.038 14.0 0.2 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Pox_MCEL PF03291.11 KND89544.1 - 0.73 8.6 2.1 31 3.2 0.1 2.8 3 0 0 3 3 3 0 mRNA capping enzyme Sulfate_transp PF00916.15 KND89545.1 - 1.6e-32 112.6 0.5 2.8e-32 111.8 0.1 1.6 1 1 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KND89545.1 - 2.7e-17 62.3 0.0 5.9e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KND89545.1 - 2e-09 36.8 0.0 4.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 KND89546.1 - 7.3e-13 48.7 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3405 PF11885.3 KND89547.1 - 4.7e-204 678.2 2.1 6.8e-204 677.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.19 KND89548.1 - 2.5e-43 147.9 0.0 2.9e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.16 KND89549.1 - 8e-80 266.1 0.2 9.1e-80 265.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND89549.1 - 3.4e-14 52.4 0.0 4.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KND89549.1 - 2.1e-13 49.9 0.0 2.3e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KND89549.1 - 1.7e-12 46.7 1.4 2.3e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KND89549.1 - 1.7e-10 40.4 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KND89549.1 - 1.8e-08 34.8 0.0 2.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KND89549.1 - 1.2e-05 25.1 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KND89549.1 - 0.0073 15.3 0.2 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 KND89549.1 - 0.049 13.4 0.2 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KND89550.1 - 5e-45 153.4 0.1 8.1e-44 149.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KND89550.1 - 2e-23 82.0 0.1 6.9e-23 80.3 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KND89550.1 - 2.1e-19 70.0 0.1 2.7e-10 40.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND89550.1 - 1.7e-13 50.4 0.1 6.4e-09 35.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KND89550.1 - 2.3e-11 44.0 7.5 0.0005 20.0 0.0 5.0 3 2 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 KND89550.1 - 7.4e-09 35.8 0.2 0.0035 17.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KND89550.1 - 1.6e-07 30.9 0.2 0.00043 19.8 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KND89550.1 - 1.8e-05 24.5 8.4 0.49 10.0 0.0 4.7 3 2 1 4 4 4 2 Archaeal ATPase NACHT PF05729.7 KND89550.1 - 4.7e-05 23.0 0.2 0.36 10.4 0.1 2.9 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KND89550.1 - 0.0001 22.6 5.3 0.13 12.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KND89550.1 - 0.00012 22.4 6.3 0.11 12.7 2.5 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KND89550.1 - 0.00037 21.2 10.3 0.019 15.7 0.1 4.0 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KND89550.1 - 0.00039 19.8 0.0 0.56 9.6 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KND89550.1 - 0.0011 18.6 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 KND89550.1 - 0.0012 19.1 1.5 0.22 11.7 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 KND89550.1 - 0.002 18.1 0.2 5.9 6.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 KND89550.1 - 0.0026 17.4 0.1 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 KND89550.1 - 0.0051 16.0 0.1 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.17 KND89550.1 - 0.0058 16.7 0.0 0.83 9.8 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KND89550.1 - 0.006 15.7 0.1 2 7.5 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND89550.1 - 0.0085 15.5 0.6 3.8 6.8 0.0 3.1 2 2 1 3 3 3 0 AAA domain AAA_33 PF13671.1 KND89550.1 - 0.0087 15.9 0.0 5 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 KND89550.1 - 0.0098 15.5 6.1 0.0098 15.5 4.2 1.7 2 0 0 2 2 1 1 IncA protein APG6 PF04111.7 KND89550.1 - 0.012 14.6 4.3 0.02 13.9 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF258 PF03193.11 KND89550.1 - 0.012 14.7 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 KND89550.1 - 0.014 14.8 0.0 0.42 10.0 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Atg14 PF10186.4 KND89550.1 - 0.025 13.5 6.0 0.054 12.4 4.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PduV-EutP PF10662.4 KND89550.1 - 0.026 13.9 0.0 0.99 8.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KND89550.1 - 0.028 13.8 0.2 0.62 9.4 0.0 3.1 2 2 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 KND89550.1 - 0.034 12.7 0.1 2.7 6.5 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.8 KND89550.1 - 0.039 12.8 0.5 1 8.2 0.2 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF815) UvrD-helicase PF00580.16 KND89550.1 - 0.039 13.2 1.9 0.41 9.8 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CENP-F_leu_zip PF10473.4 KND89550.1 - 0.072 12.9 13.2 0.29 11.0 9.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Miro PF08477.8 KND89550.1 - 0.074 13.5 1.4 4.2 7.8 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein AAA_24 PF13479.1 KND89550.1 - 0.081 12.4 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KND89550.1 - 0.1 12.3 4.0 6.8 6.4 0.1 3.6 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_15 PF13175.1 KND89550.1 - 0.11 11.5 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KND89550.1 - 0.12 11.9 0.1 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mnd1 PF03962.10 KND89550.1 - 0.21 11.2 11.1 0.4 10.3 7.7 1.4 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 KND89550.1 - 0.56 8.0 2.7 0.78 7.5 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CR6_interact PF10147.4 KND89550.1 - 0.93 8.7 10.1 1.6 8.0 7.0 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Seryl_tRNA_N PF02403.17 KND89550.1 - 2.2 8.3 14.4 5.5 7.0 8.4 2.8 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 KND89550.1 - 3.1 7.3 12.0 4.5 6.7 6.7 2.4 2 0 0 2 2 2 0 GrpE FlxA PF14282.1 KND89550.1 - 6.9 6.6 7.4 64 3.5 5.1 2.2 1 1 0 1 1 1 0 FlxA-like protein Proteasom_Rpn13 PF04683.8 KND89551.1 - 2e-26 91.9 0.0 3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 KND89551.1 - 0.015 14.7 0.1 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 L27_2 RRM_1 PF00076.17 KND89552.1 - 5.2e-10 38.8 0.0 0.00035 20.1 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND89552.1 - 9.5e-10 38.3 0.0 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND89552.1 - 3e-05 23.7 0.0 0.00038 20.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4267 PF14087.1 KND89553.1 - 4.2e-25 87.5 2.6 5e-25 87.2 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DoxX_3 PF13781.1 KND89553.1 - 0.079 13.3 0.4 0.17 12.2 0.1 1.6 1 1 0 1 1 1 0 DoxX-like family DEAD PF00270.24 KND89554.1 - 5.2e-45 152.9 0.0 8.3e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND89554.1 - 4.7e-28 96.8 0.0 9.1e-28 95.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND89554.1 - 0.0028 17.5 0.0 0.027 14.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Aldo_ket_red PF00248.16 KND89555.1 - 3.8e-50 170.2 0.0 4.6e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.4 KND89555.1 - 0.067 13.0 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Cupin_2 PF07883.6 KND89556.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KND89556.1 - 0.0067 16.0 0.2 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KND89556.1 - 0.023 14.0 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) HIT PF01230.18 KND89557.1 - 1.3e-18 67.3 0.1 2.8e-18 66.2 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KND89557.1 - 3.2e-08 33.8 0.0 7.6e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KND89557.1 - 0.00036 20.1 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Strep_his_triad PF04270.8 KND89557.1 - 0.027 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Streptococcal histidine triad protein DNA_RNApol_7kD PF03604.8 KND89558.1 - 5.7e-11 41.6 0.9 7.4e-11 41.3 0.6 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-RING_3 PF14369.1 KND89558.1 - 0.0027 17.6 0.3 0.0045 16.9 0.2 1.4 1 0 0 1 1 1 1 zinc-finger Zn-ribbon_8 PF09723.5 KND89558.1 - 0.0033 17.3 0.9 0.0086 16.0 0.6 1.7 1 1 0 1 1 1 1 Zinc ribbon domain A2L_zn_ribbon PF08792.5 KND89558.1 - 0.0045 16.4 0.6 0.0071 15.7 0.4 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain Prok-RING_1 PF14446.1 KND89558.1 - 0.0074 15.9 0.6 0.01 15.5 0.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 HypA PF01155.14 KND89558.1 - 0.01 15.5 0.2 0.011 15.3 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DnaJ_CXXCXGXG PF00684.14 KND89558.1 - 0.013 15.4 0.8 0.026 14.5 0.4 1.4 1 1 1 2 2 2 0 DnaJ central domain zf-UDP PF14569.1 KND89558.1 - 0.023 14.4 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger PhnA_Zn_Ribbon PF08274.7 KND89558.1 - 0.032 14.0 0.7 0.053 13.3 0.4 1.4 1 1 0 1 1 1 0 PhnA Zinc-Ribbon DZR PF12773.2 KND89558.1 - 0.038 13.8 0.2 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.1 KND89558.1 - 0.077 13.3 1.9 2.9 8.2 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 KND89558.1 - 0.08 12.7 2.2 0.44 10.3 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C2HC5 PF06221.8 KND89558.1 - 0.086 12.6 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type GFA PF04828.9 KND89558.1 - 0.091 12.7 0.5 4.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 KND89558.1 - 0.095 12.4 0.3 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF329 PF03884.9 KND89558.1 - 0.11 12.0 0.4 2.6 7.6 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF329) TF_Zn_Ribbon PF08271.7 KND89558.1 - 0.11 11.7 0.7 2.5 7.5 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding NinF PF05810.7 KND89558.1 - 0.13 12.0 0.2 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 NinF protein DUF1272 PF06906.6 KND89558.1 - 0.41 10.5 2.0 15 5.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) CIAPIN1 PF05093.8 KND89559.1 - 1.8e-32 111.3 4.4 2.7e-32 110.7 3.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3664 PF12406.3 KND89559.1 - 0.076 13.6 0.5 0.14 12.7 0.3 1.3 1 0 0 1 1 1 0 Surface protein TPR_11 PF13414.1 KND89560.1 - 2.9e-05 23.6 10.2 0.5 10.0 0.7 6.3 5 1 0 5 5 5 2 TPR repeat TPR_17 PF13431.1 KND89560.1 - 0.00045 20.1 0.1 6 7.3 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND89560.1 - 0.016 15.4 0.8 2.3 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND89560.1 - 0.27 12.0 5.7 24 5.9 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 KND89561.1 - 1.7e-156 520.9 0.0 2.5e-156 520.4 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ATP_bind_1 PF03029.12 KND89561.1 - 9.5e-74 247.9 0.0 1.9e-73 246.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TPR_14 PF13428.1 KND89561.1 - 1.6e-05 25.0 1.4 0.74 10.6 0.4 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND89561.1 - 4.1e-05 23.1 0.1 0.082 12.5 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KND89561.1 - 8.8e-05 22.0 0.2 0.78 9.6 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND89561.1 - 0.00013 21.5 0.7 0.21 11.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_10 PF12846.2 KND89561.1 - 0.00022 20.7 1.5 0.0045 16.4 0.2 2.6 2 1 0 2 2 2 1 AAA-like domain TPR_1 PF00515.23 KND89561.1 - 0.00029 20.2 1.0 0.44 10.2 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND89561.1 - 0.00048 19.8 5.0 0.023 14.6 0.9 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 KND89561.1 - 0.00055 20.0 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_9 PF13371.1 KND89561.1 - 0.00071 19.3 0.8 0.095 12.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_33 PF13671.1 KND89561.1 - 0.0026 17.6 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KND89561.1 - 0.0043 16.5 0.0 0.14 11.5 0.0 3.2 3 1 1 4 4 4 1 SRP54-type protein, GTPase domain ArgK PF03308.11 KND89561.1 - 0.0056 15.4 0.0 0.86 8.3 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 KND89561.1 - 0.0071 17.1 0.1 0.053 14.3 0.0 2.5 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KND89561.1 - 0.0098 15.5 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND89561.1 - 0.011 15.7 0.0 0.052 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KND89561.1 - 0.015 14.7 0.0 2.5 7.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KND89561.1 - 0.021 13.6 0.2 0.066 12.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KND89561.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KND89561.1 - 0.029 14.8 0.0 9.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 KND89561.1 - 0.094 11.9 0.0 0.94 8.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.9 KND89561.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KND89561.1 - 0.1 12.0 0.0 0.7 9.3 0.0 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TPR_16 PF13432.1 KND89561.1 - 0.12 13.0 0.8 14 6.5 0.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FTCD PF02971.9 KND89561.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase domain AAA_18 PF13238.1 KND89561.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain NDUFB10 PF10249.4 KND89562.1 - 0.0013 18.9 0.0 0.0016 18.5 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Glyoxalase_2 PF12681.2 KND89564.1 - 3.6e-12 46.8 0.0 4.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KND89564.1 - 3e-09 36.9 0.0 5.1e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KND89564.1 - 2.6e-05 24.1 0.1 0.00032 20.6 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KND89564.1 - 0.001 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tyrosinase PF00264.15 KND89565.1 - 8.6e-51 173.2 2.6 1.3e-50 172.6 1.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase AMP-binding PF00501.23 KND89566.1 - 2.1e-191 635.7 3.8 1.6e-79 267.2 0.0 3.8 3 1 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KND89566.1 - 5.6e-111 370.1 0.0 3.5e-37 127.8 0.0 4.9 5 1 0 5 5 5 3 Condensation domain PP-binding PF00550.20 KND89566.1 - 3e-28 97.8 0.3 1.1e-11 44.8 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.8 KND89566.1 - 0.00095 17.8 0.6 0.16 10.4 0.1 2.5 2 0 0 2 2 2 2 GH3 auxin-responsive promoter BTB PF00651.26 KND89567.1 - 0.0033 17.3 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Coatomer_E PF04733.9 KND89568.1 - 2.2e-60 204.3 3.5 2.6e-60 204.1 2.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KND89568.1 - 6.5e-06 26.3 16.3 0.0047 17.2 0.5 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND89568.1 - 3.3e-05 24.4 11.1 0.022 15.4 0.1 5.0 3 2 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KND89568.1 - 3.6e-05 23.8 0.5 0.083 13.0 0.1 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Type_III_YscG PF09477.5 KND89568.1 - 5.1e-05 23.3 4.2 0.28 11.2 0.0 3.8 1 1 2 3 3 3 2 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_15 PF13429.1 KND89568.1 - 0.00018 20.6 1.0 0.0091 15.0 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND89568.1 - 0.00068 19.3 6.3 0.015 15.1 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND89568.1 - 0.001 18.5 0.6 0.32 10.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND89568.1 - 0.0022 18.4 13.5 0.14 12.8 0.2 5.8 2 2 5 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND89568.1 - 0.0024 17.5 0.0 0.15 11.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 KND89568.1 - 0.0065 16.5 2.6 2.2 8.3 0.0 2.9 2 1 1 3 3 3 1 Tetratrico peptide repeat TPR_11 PF13414.1 KND89568.1 - 0.0079 15.8 4.4 0.59 9.8 0.1 4.0 3 2 3 6 6 5 2 TPR repeat TPR_6 PF13174.1 KND89568.1 - 0.033 14.6 2.1 8 7.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KND89568.1 - 0.036 14.0 6.3 1.2 9.1 0.3 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF1874 PF08960.5 KND89568.1 - 0.071 12.8 0.2 0.29 10.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1874) TPR_4 PF07721.9 KND89568.1 - 3.6 8.2 21.4 1.2 9.7 0.2 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat FYVE PF01363.16 KND89569.1 - 8.5e-23 80.0 20.3 2.2e-16 59.5 5.9 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KND89569.1 - 0.00062 19.8 5.9 0.036 14.2 0.1 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KND89569.1 - 0.00082 19.2 2.6 0.00082 19.2 1.8 3.9 4 1 0 4 4 4 1 AN1-like Zinc finger Rbsn PF11464.3 KND89569.1 - 0.00088 18.7 0.2 0.003 17.0 0.2 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain TMF_TATA_bd PF12325.3 KND89569.1 - 0.0019 17.9 2.3 0.0019 17.9 1.6 2.8 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF3719 PF12516.3 KND89569.1 - 0.054 13.0 0.6 0.2 11.2 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) DUF2225 PF09986.4 KND89569.1 - 0.058 12.8 2.9 0.14 11.5 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-NADH-PPase PF09297.6 KND89569.1 - 0.18 11.3 8.8 0.72 9.4 0.1 3.9 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain AAA_13 PF13166.1 KND89569.1 - 0.22 9.9 0.5 16 3.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain C6_DPF PF10170.4 KND89569.1 - 0.75 9.8 4.5 0.19 11.7 0.2 2.3 2 1 0 2 2 2 0 Cysteine-rich domain UPF0547 PF10571.4 KND89569.1 - 0.81 9.4 9.7 1.8 8.3 0.0 4.5 4 1 0 4 4 4 0 Uncharacterised protein family UPF0547 HypA PF01155.14 KND89569.1 - 1.7 8.3 11.7 0.66 9.6 0.9 3.5 3 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KND89569.1 - 4.6 7.3 9.1 3.7 7.6 0.1 3.9 4 0 0 4 4 4 0 zinc-finger MAD PF05557.8 KND89569.1 - 5.5 4.9 11.0 2.3 6.2 2.9 2.7 2 1 1 3 3 3 0 Mitotic checkpoint protein zf-C2H2_2 PF12756.2 KND89569.1 - 7.3 6.7 9.7 0.84 9.7 0.0 3.2 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) NAD_binding_7 PF13241.1 KND89570.1 - 1.5e-31 108.7 0.1 2.3e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KND89570.1 - 2.3e-28 97.2 0.0 3.5e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KND89570.1 - 9.4e-14 50.1 0.1 1.5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 KND89570.1 - 0.0078 16.2 0.0 0.12 12.4 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KND89570.1 - 0.014 15.3 0.2 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF3386 PF11866.3 KND89570.1 - 0.058 12.5 0.0 0.63 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3386) ThiF PF00899.16 KND89570.1 - 0.2 11.4 0.6 0.43 10.4 0.1 1.7 1 1 1 2 2 2 0 ThiF family CENP-L PF13092.1 KND89571.1 - 6e-49 165.9 0.0 5.1e-46 156.4 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 5_nucleotid_C PF02872.13 KND89572.1 - 2.9e-34 118.2 0.0 5.2e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain PGA_cap PF09587.5 KND89572.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap MBF1 PF08523.5 KND89573.1 - 3.1e-22 78.3 0.8 6.2e-22 77.4 0.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KND89573.1 - 3.9e-10 39.4 0.0 6.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KND89573.1 - 8.2e-05 22.5 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KND89573.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.4 KND89573.1 - 0.036 13.6 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF1365 PF07103.6 KND89574.1 - 4.3e-31 107.8 0.0 7.4e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.9 KND89575.1 - 3e-23 81.5 0.0 4.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KND89575.1 - 0.073 12.3 0.2 0.32 10.2 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KND89575.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 KND89575.1 - 0.13 11.7 0.9 0.28 10.7 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KND89575.1 - 0.54 10.1 3.0 1.7 8.5 1.1 2.3 2 1 1 3 3 3 0 Double zinc ribbon OTT_1508_deam PF14441.1 KND89576.1 - 4.6e-16 58.9 0.7 4.6e-16 58.9 0.5 2.4 3 0 0 3 3 3 1 OTT_1508-like deaminase adh_short PF00106.20 KND89579.1 - 1e-24 87.3 6.1 1.4e-24 86.8 4.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND89579.1 - 2.3e-23 83.2 0.0 2.8e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND89579.1 - 6.5e-15 55.2 4.5 1.3e-14 54.3 3.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND89579.1 - 9.8e-08 31.7 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND89579.1 - 2.4e-06 26.4 0.1 3.2e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KND89579.1 - 0.00076 18.4 0.1 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.1 KND89579.1 - 0.015 15.3 0.4 0.037 14.0 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 KND89579.1 - 0.025 14.5 3.8 0.023 14.6 1.1 2.0 2 1 0 2 2 2 0 NADH(P)-binding TrkA_N PF02254.13 KND89579.1 - 0.039 13.9 0.2 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KND89579.1 - 0.11 11.3 0.2 0.11 11.3 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase AAA_10 PF12846.2 KND89580.1 - 3.1e-09 36.7 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain 3-alpha PF03475.9 KND89580.1 - 0.0046 16.6 0.1 0.026 14.2 0.0 2.3 3 0 0 3 3 3 1 3-alpha domain AAA_22 PF13401.1 KND89580.1 - 0.0065 16.6 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KND89580.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KND89580.1 - 0.035 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.7 KND89580.1 - 0.047 13.1 0.1 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF3153 PF11353.3 KND89580.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) GST_N_3 PF13417.1 KND89581.1 - 9.2e-25 86.6 0.0 3.9e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND89581.1 - 2.8e-17 62.4 0.5 1.5e-16 60.1 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KND89581.1 - 9e-09 35.3 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KND89581.1 - 2.7e-07 30.3 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KND89581.1 - 0.0031 17.4 0.0 0.0096 15.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND89581.1 - 0.006 17.0 0.2 0.023 15.1 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain RrnaAD PF00398.15 KND89582.1 - 1.2e-56 191.6 0.0 1.7e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KND89582.1 - 4.5e-10 39.5 0.0 7.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89582.1 - 3.5e-06 27.5 0.0 6.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND89582.1 - 0.00033 20.0 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KND89582.1 - 0.00041 19.5 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KND89582.1 - 0.00077 19.8 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89582.1 - 0.00089 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND89582.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KND89582.1 - 0.0018 17.4 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 KND89582.1 - 0.0044 16.5 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KND89582.1 - 0.031 14.6 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Sigma70_ner PF04546.8 KND89582.1 - 0.1 12.1 2.8 0.16 11.5 1.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PRP1_N PF06424.7 KND89583.1 - 5.5e-49 165.9 6.8 1.1e-48 164.8 4.7 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KND89583.1 - 5.7e-29 97.9 30.8 0.05 14.2 0.0 13.8 5 3 9 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 KND89583.1 - 8.7e-20 70.8 15.7 0.0026 18.0 0.0 9.4 6 3 4 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 KND89583.1 - 2.3e-19 69.5 17.4 0.0025 18.4 0.0 8.9 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KND89583.1 - 1.5e-16 59.8 4.0 0.0084 15.7 0.0 8.2 8 2 2 10 10 10 4 TPR repeat TPR_2 PF07719.12 KND89583.1 - 3.9e-09 35.7 8.7 0.057 13.3 0.0 9.0 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND89583.1 - 1e-08 34.7 1.6 8.8 6.8 0.0 9.1 11 1 0 11 11 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND89583.1 - 1.3e-05 24.5 0.1 0.38 10.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND89583.1 - 4.6e-05 22.8 0.4 0.43 10.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 KND89583.1 - 0.0004 19.2 5.8 0.8 8.3 0.0 5.2 3 1 3 6 6 6 3 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 KND89583.1 - 0.012 15.5 2.7 4.9 7.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KND89583.1 - 0.035 14.0 9.3 1.6 8.6 0.2 4.5 3 2 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND89583.1 - 0.12 12.2 0.0 0.12 12.2 0.0 5.0 5 2 1 6 6 6 0 Tetratricopeptide repeat Hep_59 PF07052.6 KND89583.1 - 2.1 8.7 8.5 6.8 7.1 2.1 3.2 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Vac7 PF12751.2 KND89585.1 - 3.7e-124 414.4 8.7 3.7e-124 414.4 6.1 1.9 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 zf-PHD-like PF15446.1 KND89587.1 - 2.9e-70 235.0 11.3 5.7e-70 234.1 7.8 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KND89587.1 - 1.3e-52 178.5 0.0 1.9e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND89587.1 - 4.1e-14 52.1 0.0 1.6e-13 50.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KND89587.1 - 3.5e-08 32.6 3.4 7.9e-08 31.4 2.4 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KND89587.1 - 9.3e-07 28.4 0.1 0.00021 20.8 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KND89587.1 - 8.9e-06 25.3 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 KND89587.1 - 0.00021 20.8 7.9 0.00021 20.8 5.4 3.3 2 2 1 3 3 3 1 PHD-finger PHD_2 PF13831.1 KND89587.1 - 0.0013 17.9 3.3 0.0013 17.9 2.3 3.1 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KND89587.1 - 0.33 10.7 11.4 0.055 13.2 3.3 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Complex1_LYR PF05347.10 KND89589.1 - 8.8e-09 35.0 1.7 3.6e-08 33.0 0.9 2.1 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND89589.1 - 5.8e-08 32.8 2.5 1.6e-07 31.4 1.8 1.9 1 1 0 1 1 1 1 Complex1_LYR-like SpoU_methylase PF00588.14 KND89591.1 - 2.3e-21 76.1 0.0 4.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KND89591.1 - 7.7e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Ank_4 PF13637.1 KND89592.1 - 9.2e-17 61.0 2.5 9.4e-10 38.7 0.1 4.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND89592.1 - 3.6e-15 56.0 0.2 5.1e-05 23.5 0.0 3.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND89592.1 - 3.4e-12 46.1 0.3 0.00024 21.2 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KND89592.1 - 1.4e-11 43.6 3.7 9.2e-06 25.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KND89592.1 - 2.4e-11 42.6 0.7 0.00034 20.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KND89592.1 - 7.9e-05 22.2 0.7 0.00037 20.1 0.2 2.2 2 1 0 2 2 2 1 KilA-N domain FliJ PF02050.11 KND89592.1 - 0.19 11.7 7.4 0.26 11.3 4.1 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein OmpH PF03938.9 KND89592.1 - 1.3 8.9 6.4 3.1 7.7 4.4 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AA_permease_2 PF13520.1 KND89593.1 - 1.5e-89 300.5 34.4 2e-89 300.0 23.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND89593.1 - 7.9e-17 60.7 28.8 1.1e-16 60.2 19.9 1.2 1 0 0 1 1 1 1 Amino acid permease TcdA_TcdB_pore PF12920.2 KND89593.1 - 0.19 9.6 0.4 0.27 9.0 0.3 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PsbN PF02468.10 KND89593.1 - 3.6 7.2 6.2 0.76 9.4 1.0 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) MFS_1 PF07690.11 KND89595.1 - 2e-33 115.6 27.3 2e-33 115.6 18.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 KND89595.1 - 0.14 10.5 1.0 0.21 9.9 0.7 1.2 1 0 0 1 1 1 0 Chitin synthase Cyt-b5 PF00173.23 KND89597.1 - 2.1e-13 49.8 0.0 3.2e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2_4 PF13894.1 KND89602.1 - 0.032 14.5 13.3 0.18 12.1 0.4 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KND89604.1 - 0.0013 18.9 11.7 0.003 17.7 3.1 8.4 8 1 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND89604.1 - 0.0032 17.6 70.6 0.017 15.4 1.8 8.4 8 1 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND89604.1 - 0.019 15.1 28.5 0.26 11.4 0.7 6.9 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding AAA PF00004.24 KND89605.1 - 3.5e-16 59.6 0.0 5.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND89605.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 KND89606.1 - 1e-09 38.2 0.0 0.054 13.4 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KND89606.1 - 2.4e-08 33.4 1.9 0.003 17.1 0.0 3.8 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 KND89606.1 - 0.00031 20.2 4.8 1.3 8.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND89606.1 - 0.00033 20.3 2.9 0.45 10.5 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND89606.1 - 0.00058 20.2 0.5 23 6.0 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND89606.1 - 0.021 14.6 0.2 1.4 8.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FANCI_S1 PF14675.1 KND89606.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 Apolipoprotein PF01442.13 KND89607.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KND89607.1 - 1.1 9.7 5.0 0.46 10.9 1.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) JAB PF01398.16 KND89608.1 - 5.2e-17 61.6 0.0 9.3e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KND89608.1 - 8.9e-13 48.3 0.1 1.5e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function SUZ PF12752.2 KND89609.1 - 1.8e-11 44.3 2.2 1.8e-11 44.3 1.5 2.7 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 KND89609.1 - 2.9e-07 30.0 0.0 7.2e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.14 KND89610.1 - 1.6e-28 99.0 0.7 5.3e-28 97.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 MRFAP1 PF15155.1 KND89610.1 - 3.8 7.8 7.5 6.5 7.1 0.1 2.4 2 1 0 2 2 2 0 MORF4 family-associated protein1 DUF1253 PF06862.7 KND89611.1 - 4e-163 542.9 0.0 5.2e-163 542.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 KND89611.1 - 0.0022 17.4 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase APH_6_hur PF04655.9 KND89611.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase ALAD PF00490.16 KND89612.1 - 1.1e-119 399.1 0.0 1.3e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Tox-MPTase2 PF15638.1 KND89613.1 - 0.14 11.6 0.0 0.43 10.0 0.0 1.8 1 1 0 1 1 1 0 Metallopeptidase toxin 2 Flagellin_N PF00669.15 KND89613.1 - 0.19 11.5 2.0 0.32 10.8 0.5 2.0 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF883 PF05957.8 KND89613.1 - 1.4 9.3 16.8 2.4 8.6 3.6 3.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Amidohydro_3 PF07969.6 KND89614.1 - 1.5e-63 215.4 5.0 2.1e-63 214.9 3.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND89614.1 - 0.00064 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Botulinum_HA-17 PF05588.6 KND89615.1 - 0.0067 16.3 0.1 0.0091 15.8 0.0 1.1 1 0 0 1 1 1 1 Clostridium botulinum HA-17 protein DUF3527 PF12043.3 KND89615.1 - 0.011 15.2 0.3 0.012 15.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) SAGA-Tad1 PF12767.2 KND89615.1 - 0.25 10.9 3.3 0.32 10.6 2.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Y_phosphatase3 PF13350.1 KND89616.1 - 4.5e-31 108.3 0.0 6.2e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KND89616.1 - 1.6e-11 44.1 0.0 2.6e-10 40.2 0.0 2.9 3 0 0 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KND89616.1 - 0.00077 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KND89616.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SCP2 PF02036.12 KND89617.1 - 6e-25 87.5 0.5 6.8e-25 87.3 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KND89617.1 - 1.6e-05 24.9 0.2 2.3e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 KND89617.1 - 0.039 13.3 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain LETM1 PF07766.8 KND89618.1 - 2e-10 40.1 0.7 4.8e-09 35.6 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein Zn_clus PF00172.13 KND89619.1 - 6.9e-09 35.4 13.5 1.1e-08 34.8 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ca_chan_IQ PF08763.6 KND89619.1 - 2.3 7.5 5.6 4.3 6.6 3.9 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain WD40 PF00400.27 KND89621.1 - 8.6e-33 111.0 6.5 1e-07 31.5 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KND89621.1 - 2e-05 23.5 0.0 0.026 13.2 0.0 3.4 2 1 0 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 KND89621.1 - 0.0013 18.2 1.1 2.8 7.3 0.0 3.2 2 1 0 3 3 3 2 PQQ-like domain eIF2A PF08662.6 KND89621.1 - 0.0014 18.3 0.0 0.25 11.0 0.0 3.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KND89621.1 - 0.0025 16.0 0.7 0.056 11.5 0.0 2.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 TSNR_N PF04705.7 KND89621.1 - 0.17 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus PQQ_3 PF13570.1 KND89621.1 - 6.2 7.2 8.1 8.3 6.8 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain APG5 PF04106.7 KND89622.1 - 3.6e-42 144.1 0.0 6.2e-42 143.3 0.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg5 PLAC PF08686.6 KND89623.1 - 0.04 14.1 0.2 0.054 13.7 0.1 1.2 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain GAF_2 PF13185.1 KND89624.1 - 0.0031 18.0 0.0 0.0073 16.8 0.0 1.6 1 1 0 1 1 1 1 GAF domain C2 PF00168.25 KND89625.1 - 2.9e-13 49.4 0.0 4.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain UTP15_C PF09384.5 KND89626.1 - 3e-41 140.5 0.0 4.6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KND89626.1 - 1.2e-28 97.9 4.2 3.3e-10 39.4 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-U1 PF06220.7 KND89628.1 - 1.4e-15 56.5 1.5 2.1e-15 55.9 1.0 1.3 1 0 0 1 1 1 1 U1 zinc finger Sdh5 PF03937.11 KND89629.1 - 4.7e-23 80.6 0.0 1e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase MIS13 PF08202.6 KND89630.1 - 9.9e-61 205.4 0.5 2.3e-60 204.2 0.3 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family eIF-3_zeta PF05091.7 KND89630.1 - 0.78 8.2 9.8 0.44 9.1 5.5 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EMP24_GP25L PF01105.19 KND89631.1 - 5e-41 140.4 0.0 6.1e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 KND89631.1 - 0.15 10.1 0.4 0.2 9.7 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MARVEL PF01284.18 KND89632.1 - 3.1e-06 27.0 15.0 4.2e-06 26.6 10.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain PrgI PF12666.2 KND89632.1 - 0.21 11.7 4.6 0.4 10.8 3.2 1.5 1 0 0 1 1 1 0 PrgI family protein Peptidase_S10 PF00450.17 KND89633.1 - 3e-113 379.1 0.0 3.9e-113 378.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KND89633.1 - 1.3e-06 28.4 0.0 5.7e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Act-Frag_cataly PF09192.5 KND89633.1 - 0.012 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic RNA_Me_trans PF04252.8 KND89634.1 - 2.2e-46 157.7 0.0 2.5e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Aft1_HRA PF11786.3 KND89635.1 - 5.8e-30 103.3 10.2 5.8e-30 103.3 7.1 3.8 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.3 KND89635.1 - 4.4e-22 78.9 8.3 4.4e-22 78.9 5.7 4.5 3 2 2 5 5 5 1 Aft1 HRR domain Aft1_OSA PF11785.3 KND89635.1 - 5.9e-19 68.3 10.5 5.9e-19 68.3 7.3 4.4 6 0 0 6 6 6 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 KND89635.1 - 1.9e-13 50.1 5.7 3.1e-13 49.4 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND89635.1 - 1.1e-06 28.3 5.9 2.1e-06 27.4 4.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KND89635.1 - 0.0022 18.2 3.0 0.0022 18.2 2.1 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor zf-CCHC PF00098.18 KND89636.1 - 0.069 13.1 14.7 0.11 12.4 1.0 4.2 4 0 0 4 4 4 0 Zinc knuckle Ribosomal_L40e PF01020.12 KND89636.1 - 0.096 12.2 3.3 0.24 11.0 2.3 1.6 1 0 0 1 1 1 0 Ribosomal L40e family Dynamin_N PF00350.18 KND89637.1 - 7.9e-32 110.3 0.0 2e-31 109.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND89637.1 - 1.5e-20 73.2 0.0 3.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 KND89637.1 - 0.00033 20.5 1.1 0.0023 17.7 0.1 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KND89637.1 - 0.0025 17.7 0.1 0.022 14.7 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND89637.1 - 0.0047 17.4 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KND89637.1 - 0.084 12.1 0.0 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B HEAT PF02985.17 KND89638.1 - 2.2e-12 45.9 3.5 0.076 13.1 0.0 5.6 5 1 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 KND89638.1 - 4.9e-06 26.8 0.1 0.062 13.8 0.1 3.2 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 KND89638.1 - 1.4e-05 25.3 0.4 0.0014 18.8 0.1 2.9 1 1 2 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 KND89638.1 - 0.0047 15.3 0.2 0.0066 14.8 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KND89638.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 KND89638.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NAD_binding_9 PF13454.1 KND89638.1 - 0.15 11.8 0.0 0.98 9.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyridoxal_deC PF00282.14 KND89639.1 - 1.9e-25 89.1 0.0 2.3e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KND89639.1 - 0.0095 14.9 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KND89639.1 - 0.011 14.9 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2462 PF09495.5 KND89640.1 - 6.2e-11 42.8 8.6 8.3e-11 42.4 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Peptidase_M48 PF01435.13 KND89641.1 - 1.3e-38 132.8 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cyt-b5 PF00173.23 KND89642.1 - 9.8e-19 66.9 0.2 1.1e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1699 PF08004.6 KND89642.1 - 0.036 13.5 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Methyltransf_23 PF13489.1 KND89643.1 - 1e-12 48.0 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89643.1 - 1.2e-06 29.0 0.0 1.3e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89643.1 - 2.6e-05 23.8 0.0 0.00016 21.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89643.1 - 0.0022 18.4 0.0 0.0082 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89643.1 - 0.025 14.9 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KND89643.1 - 0.049 12.7 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cupin_5 PF06172.6 KND89644.1 - 3.1e-25 88.6 0.0 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Aconitase PF00330.15 KND89646.1 - 1.7e-147 491.7 0.0 4.1e-147 490.4 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KND89646.1 - 2.8e-37 127.7 0.0 5.2e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Nucleopor_Nup85 PF07575.8 KND89646.1 - 1.6e-11 43.1 0.0 8.1e-10 37.5 0.0 2.7 1 1 0 1 1 1 1 Nup85 Nucleoporin DUF521 PF04412.8 KND89646.1 - 0.26 9.7 0.0 0.44 9.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Pox_Ag35 PF03286.9 KND89646.1 - 0.34 10.3 4.0 0.64 9.5 2.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 KND89646.1 - 4.3 5.1 19.8 7 4.4 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.6 KND89646.1 - 4.9 7.0 20.9 11 5.8 14.5 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.7 KND89646.1 - 8.4 5.5 14.8 14 4.8 10.2 1.3 1 0 0 1 1 1 0 SDA1 WD40 PF00400.27 KND89647.1 - 6.5e-51 168.4 20.5 6.8e-10 38.4 0.1 11.1 11 0 0 11 11 11 9 WD domain, G-beta repeat IlvN PF07991.7 KND89647.1 - 4e-45 153.1 0.0 1e-44 151.8 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KND89647.1 - 7.6e-42 142.6 0.0 1.2e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain eIF2A PF08662.6 KND89647.1 - 0.00019 21.1 1.5 0.049 13.3 0.1 3.4 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KND89647.1 - 0.042 12.6 0.3 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region F420_oxidored PF03807.12 KND89647.1 - 0.084 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.11 KND89648.1 - 5.2e-18 65.2 0.0 4.4e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KND89648.1 - 0.0063 15.7 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 MRP-S28 PF10213.4 KND89649.1 - 1.4e-43 147.9 0.2 2.8e-43 147.0 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein EXOSC1 PF10447.4 KND89650.1 - 0.00025 20.9 0.1 0.0014 18.5 0.1 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KND89650.1 - 0.00061 19.0 0.0 0.096 11.9 0.0 2.7 2 0 0 2 2 2 2 Exosome complex exonuclease RRP4 N-terminal region Adap_comp_sub PF00928.16 KND89653.1 - 1.7e-61 207.6 0.0 7.4e-61 205.5 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KND89653.1 - 0.005 16.5 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.16 KND89654.1 - 6.9e-22 78.1 0.1 7.4e-17 61.6 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain Laminin_II PF06009.7 KND89654.1 - 0.17 11.6 0.3 0.35 10.6 0.2 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF1658 PF07871.6 KND89657.1 - 0.12 11.9 0.6 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) BTB PF00651.26 KND89658.1 - 7.1e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Trypan_PARP PF05887.6 KND89658.1 - 0.034 13.9 19.4 0.059 13.1 13.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pheromone PF08015.6 KND89658.1 - 0.7 10.7 4.6 0.21 12.4 0.6 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone NAD_binding_10 PF13460.1 KND89659.1 - 1e-07 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND89659.1 - 0.00046 19.1 0.0 0.0032 16.4 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 KND89659.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 KND89659.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CTP_transf_1 PF01148.15 KND89660.1 - 2e-78 263.6 29.5 2.5e-78 263.3 20.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Methyltransf_23 PF13489.1 KND89660.1 - 3.3e-20 72.4 0.0 9.1e-20 70.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89660.1 - 4.3e-09 36.9 0.0 4.2e-08 33.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND89660.1 - 1e-06 29.1 0.0 4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89660.1 - 3.4e-06 26.7 0.0 2.3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89660.1 - 3.4e-06 27.4 0.0 1.8e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND89660.1 - 0.0076 16.2 0.0 0.04 13.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KND89660.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF3636 PF12331.3 KND89661.1 - 1.1e-29 102.9 1.1 4.3e-29 101.0 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) Med15 PF09606.5 KND89661.1 - 0.0026 16.0 44.4 0.0034 15.6 30.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 KND89661.1 - 0.37 10.3 26.1 0.18 11.4 1.7 2.4 2 0 0 2 2 2 0 IncA protein Mitofilin PF09731.4 KND89661.1 - 5.5 5.5 24.5 1.9e+02 0.4 17.0 2.1 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.2 KND89661.1 - 5.8 4.4 7.3 9.9 3.6 5.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glycos_transf_1 PF00534.15 KND89662.1 - 8.8e-36 122.9 0.0 1.3e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KND89662.1 - 8.1e-18 64.8 0.0 1.9e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KND89662.1 - 3.7e-13 49.9 0.0 7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KND89662.1 - 2.9e-10 40.2 0.0 7.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KND89662.1 - 2.3e-05 24.1 0.0 7.2e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF485 PF04341.7 KND89662.1 - 0.05 13.3 0.4 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Dehydratase_LU PF02286.10 KND89664.1 - 0.068 11.4 0.1 0.074 11.2 0.1 1.1 1 0 0 1 1 1 0 Dehydratase large subunit UDPG_MGDP_dh_N PF03721.9 KND89665.1 - 3.4e-49 166.7 0.0 2.5e-31 108.5 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KND89665.1 - 4.2e-29 100.6 0.1 8.1e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KND89665.1 - 1.6e-22 79.6 0.0 4.2e-17 62.2 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 KND89665.1 - 5.2e-05 23.0 0.0 0.67 9.6 0.0 3.5 3 0 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KND89665.1 - 0.0067 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KND89665.1 - 0.015 15.1 0.0 1.1 9.1 0.0 2.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KND89665.1 - 0.036 13.7 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KND89666.1 - 1.2e-08 35.1 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KND89666.1 - 0.00074 19.4 0.1 0.0027 17.6 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KND89666.1 - 0.013 14.4 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 KND89666.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 KND89666.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF4038 PF13204.1 KND89666.1 - 0.058 12.7 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Semialdhyde_dh PF01118.19 KND89666.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KND89666.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND89666.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 KND89667.1 - 2e-21 76.1 34.8 2e-21 76.1 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B561 PF03188.11 KND89668.1 - 2.3e-06 27.4 12.4 2.3e-06 27.4 8.6 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KND89668.1 - 1.4e-05 24.6 4.8 1.9e-05 24.1 2.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.15 KND89668.1 - 0.014 14.8 9.1 0.39 10.0 6.3 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1461 PF07314.6 KND89668.1 - 0.3 10.8 0.0 0.3 10.8 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1461) DUF2306 PF10067.4 KND89668.1 - 0.63 10.1 12.6 0.34 11.0 2.0 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Caps_synth_CapC PF14102.1 KND89668.1 - 0.69 10.0 7.6 4.6 7.3 1.6 2.3 2 0 0 2 2 2 0 Capsule biosynthesis CapC Cytochrom_B_N PF00033.14 KND89668.1 - 2.2 7.5 16.3 12 5.2 11.3 2.3 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB RseC_MucC PF04246.7 KND89668.1 - 7.7 6.0 9.9 1.5 8.4 0.6 2.7 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DnaJ PF00226.26 KND89670.1 - 1.8e-11 43.6 0.5 2.7e-11 43.0 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L44 PF00935.14 KND89671.1 - 1.1e-34 118.2 12.2 1.6e-34 117.7 8.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ureidogly_hydro PF04115.7 KND89674.1 - 3.5e-44 150.0 0.0 4.5e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase MFS_1 PF07690.11 KND89675.1 - 2.3e-33 115.3 58.3 6.7e-29 100.7 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND89675.1 - 1.1e-19 70.4 22.7 3.1e-14 52.4 5.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PC4 PF02229.11 KND89676.1 - 6.3e-21 73.3 0.2 1.2e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.1 KND89676.1 - 0.011 15.8 0.3 0.011 15.8 0.2 1.7 1 1 1 2 2 2 0 YqfQ-like protein DTHCT PF08070.6 KND89676.1 - 0.22 12.2 7.9 0.2 12.3 1.0 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region Pex24p PF06398.6 KND89677.1 - 0.00011 21.1 4.6 0.00022 20.1 3.2 1.5 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.1 KND89677.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) K_trans PF02705.11 KND89681.1 - 4.7e-182 606.0 17.4 5.5e-182 605.8 12.1 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF3433 PF11915.3 KND89682.1 - 7.5e-44 147.8 10.5 1.3e-26 92.6 1.2 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) TRP PF06011.7 KND89683.1 - 2e-149 497.9 31.7 2.5e-149 497.6 22.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND89683.1 - 2.2e-39 134.7 0.2 3.5e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 ML-like domain TPR_16 PF13432.1 KND89684.1 - 0.00078 20.0 0.0 1.7 9.4 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND89684.1 - 0.018 14.9 0.0 0.18 11.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF483 PF04467.7 KND89684.1 - 0.079 13.0 0.1 6.9 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF483) TPR_6 PF13174.1 KND89684.1 - 0.11 13.0 0.0 0.51 10.9 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND89684.1 - 0.12 12.1 0.0 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidohydro_4 PF13147.1 KND89687.1 - 3.6e-06 27.2 0.0 6.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KND89687.1 - 3.9e-06 26.6 0.0 8.1e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Rad52_Rad22 PF04098.10 KND89688.1 - 5.1e-61 204.9 0.0 7e-61 204.4 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 KND89688.1 - 2.9 6.0 15.6 3.8 5.6 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cut8_C PF08559.5 KND89689.1 - 1.2e-43 148.4 0.0 1.5e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KND89689.1 - 1.2e-13 50.5 0.0 2.5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KND89689.1 - 2.2e-09 37.1 1.1 3.9e-09 36.3 0.7 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain RRM_6 PF14259.1 KND89690.1 - 4e-20 71.5 0.0 1.1e-09 38.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND89690.1 - 1e-19 69.8 0.3 2.4e-12 46.2 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KND89690.1 - 4.9e-05 23.1 0.4 0.0025 17.6 0.1 2.7 1 1 1 2 2 2 1 RNA binding motif RRM_5 PF13893.1 KND89690.1 - 0.0051 16.6 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIE-A_C-term PF11521.3 KND89690.1 - 0.051 13.5 0.7 0.16 11.9 0.0 2.2 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-CCHC_4 PF14392.1 KND89694.1 - 2.5 7.8 19.2 6.1 6.5 0.1 4.6 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC PF00098.18 KND89694.1 - 5.3 7.1 39.3 1 9.4 0.9 6.0 7 0 0 7 7 7 0 Zinc knuckle Methyltransf_3 PF01596.12 KND89696.1 - 1.9e-36 125.0 0.0 2.7e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KND89696.1 - 2.1e-11 44.5 0.0 5.7e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND89696.1 - 4.1e-11 42.8 0.0 5.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KND89696.1 - 1.1e-10 42.0 0.0 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89696.1 - 5.6e-09 35.7 0.0 6.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND89696.1 - 7.5e-07 29.1 0.1 1.6e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND89696.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89696.1 - 0.0019 18.5 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89696.1 - 0.0023 18.3 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND89696.1 - 0.0088 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF2783 PF10932.3 KND89696.1 - 0.016 14.7 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) Methyltransf_23 PF13489.1 KND89696.1 - 0.046 13.4 0.0 0.082 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KND89696.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SUR7 PF06687.7 KND89697.1 - 8.5e-08 32.0 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Acetyltransf_7 PF13508.1 KND89699.1 - 1.8e-07 31.2 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND89699.1 - 8.2e-07 29.1 0.0 2.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND89699.1 - 1.2e-06 28.3 0.3 2.5e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KND89699.1 - 2e-05 24.4 0.1 4.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND89699.1 - 0.0034 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KND89699.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.20 KND89700.1 - 2.9e-35 121.6 0.0 3.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89700.1 - 5.6e-15 55.1 0.0 7.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND89700.1 - 0.014 15.1 0.0 0.12 12.0 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 KND89701.1 - 4.3e-52 176.4 0.0 5.1e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NMO PF03060.10 KND89702.1 - 5.2e-24 84.9 6.5 1.2e-16 60.7 1.8 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase Aldo_ket_red PF00248.16 KND89703.1 - 7.6e-71 238.2 0.0 9e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PRD_Mga PF08270.6 KND89703.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain FliG_M PF14841.1 KND89703.1 - 0.096 12.7 0.1 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 FliG middle domain Fungal_trans PF04082.13 KND89704.1 - 2.2e-17 62.8 0.0 4.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89704.1 - 9.4e-08 31.8 9.2 1.9e-07 30.8 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.14 KND89704.1 - 0.4 10.3 2.5 0.88 9.2 1.8 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PPR_2 PF13041.1 KND89705.1 - 2.1e-15 56.4 0.0 7.7e-07 28.9 0.0 5.4 5 1 1 6 6 6 3 PPR repeat family PPR_1 PF12854.2 KND89705.1 - 2.4e-09 36.4 0.0 0.0035 16.7 0.0 3.9 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 KND89705.1 - 2.7e-08 33.4 0.2 0.016 15.4 0.0 3.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.15 KND89705.1 - 6.8e-07 28.8 0.0 0.042 13.8 0.0 4.5 4 0 0 4 4 4 3 PPR repeat Hexapep PF00132.19 KND89707.1 - 6.3e-13 47.6 19.4 1.4e-07 30.6 2.0 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KND89707.1 - 1.2e-11 43.9 18.2 1.9e-06 27.3 1.4 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KND89707.1 - 2.4e-10 40.2 0.0 6.6e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase Acetyltransf_11 PF13720.1 KND89707.1 - 0.061 13.5 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 cwf18 PF08315.7 KND89708.1 - 3.7e-43 147.0 5.2 3.7e-43 147.0 3.6 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.1 KND89709.1 - 1e-13 50.7 5.6 1.7e-10 40.4 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle CAML PF14963.1 KND89709.1 - 9.8 5.4 7.9 2 7.7 3.0 1.6 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand A_deaminase PF00962.17 KND89711.1 - 5.5e-41 140.5 0.0 2.7e-40 138.3 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase NmrA PF05368.8 KND89712.1 - 6.9e-08 32.0 0.0 1.3e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND89712.1 - 4.7e-07 29.9 0.1 1.1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KND89712.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KND89712.1 - 0.017 15.1 0.2 0.037 14.0 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 KND89712.1 - 0.03 13.0 0.1 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KND89712.1 - 0.035 13.0 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 KND89712.1 - 0.054 12.9 0.1 0.081 12.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Hydantoinase_B PF02538.9 KND89713.1 - 6.5e-200 664.8 0.0 2.9e-193 642.8 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KND89713.1 - 1.7e-69 234.1 0.9 2.5e-69 233.5 0.2 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Peptidase_C58 PF03543.9 KND89713.1 - 1.9 7.9 5.1 0.88 9.0 0.1 2.4 3 0 0 3 3 3 0 Yersinia/Haemophilus virulence surface antigen ADH_N PF08240.7 KND89714.1 - 1.5e-28 98.7 2.4 3.4e-28 97.5 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND89714.1 - 2.5e-19 69.1 0.5 4.9e-19 68.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND89714.1 - 0.0048 16.2 0.3 0.0084 15.5 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.14 KND89714.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase HhH-GPD PF00730.20 KND89715.1 - 4.4e-16 59.1 0.0 1.2e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KND89715.1 - 7.3e-08 31.6 0.0 1.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif RseC_MucC PF04246.7 KND89715.1 - 0.065 12.8 1.9 0.12 11.9 1.3 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Acyl-CoA_dh_1 PF00441.19 KND89718.1 - 4.4e-13 49.5 0.0 2.2e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KND89718.1 - 2.5e-08 33.3 0.0 5.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain YpzI PF14140.1 KND89720.1 - 0.31 10.5 2.4 12 5.5 0.0 3.2 3 0 0 3 3 3 0 YpzI-like protein WSS_VP PF12175.3 KND89722.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP SPX PF03105.14 KND89723.1 - 1.6e-12 47.7 0.2 5.4e-05 23.1 0.0 2.5 2 1 0 2 2 2 2 SPX domain PSI_PsaF PF02507.10 KND89723.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DUF1469 PF07332.6 KND89723.1 - 3.2 7.4 5.9 0.44 10.2 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Ceramidase_alk PF04734.8 KND89725.1 - 4.7e-262 870.7 0.0 5.4e-262 870.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase SIS PF01380.17 KND89726.1 - 3.6e-12 46.0 0.0 7.7e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KND89726.1 - 0.00059 19.5 0.0 0.0017 18.0 0.0 1.7 1 1 1 2 2 2 1 SIS domain Tctex-1 PF03645.8 KND89727.1 - 2.1e-33 114.1 0.0 2.4e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 KND89729.1 - 1.4e-13 50.7 5.1 1.4e-13 50.7 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1430 PF07242.6 KND89729.1 - 0.024 14.6 2.3 1.5 8.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) O-antigen_lig PF13425.1 KND89729.1 - 0.068 13.1 4.0 0.098 12.6 2.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SIT PF15330.1 KND89729.1 - 0.081 13.0 0.1 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Dpy19 PF10034.4 KND89729.1 - 0.1 10.7 0.9 0.13 10.4 0.7 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF2615 PF11027.3 KND89729.1 - 0.71 9.8 2.4 10 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Alba PF01918.16 KND89730.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Alba DUF3616 PF12275.3 KND89730.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) DUF1279 PF06916.8 KND89732.1 - 7.2e-30 103.1 0.4 1.2e-29 102.4 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Myb_DNA-binding PF00249.26 KND89733.1 - 1.2e-21 76.4 1.3 2.8e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND89733.1 - 4.7e-18 65.0 2.0 1.4e-12 47.4 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.1 KND89733.1 - 0.04 13.5 0.2 0.083 12.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 KND89733.1 - 0.053 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2774 PF11242.3 KND89733.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) APC_CDC26 PF10471.4 KND89734.1 - 0.51 11.1 5.6 1.1 10.0 3.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 KND89734.1 - 2.3 6.3 13.1 2.3 6.3 9.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PNGaseA PF12222.3 KND89735.1 - 7.8e-108 361.0 0.0 1.1e-107 360.6 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF2950 PF11453.3 KND89735.1 - 0.028 13.4 0.8 0.045 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) MARVEL PF01284.18 KND89737.1 - 1.8e-26 92.6 18.9 2.1e-26 92.4 13.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain HlyIII PF03006.15 KND89737.1 - 2.9 7.2 10.8 1.3 8.4 4.6 1.9 2 0 0 2 2 2 0 Haemolysin-III related eIF-5_eIF-2B PF01873.12 KND89738.1 - 4.8e-45 152.2 0.6 7.7e-45 151.5 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Fez1 PF06818.10 KND89738.1 - 0.011 15.8 0.5 0.019 14.9 0.4 1.3 1 0 0 1 1 1 0 Fez1 Lar_restr_allev PF14354.1 KND89738.1 - 0.048 13.9 0.2 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-HYPF PF07503.7 KND89738.1 - 0.67 9.4 3.8 3 7.3 2.8 2.0 1 1 1 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.5 KND89738.1 - 1.1 9.4 7.7 1 9.5 0.2 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain HSP90 PF00183.13 KND89738.1 - 3.5 5.9 10.4 6.7 4.9 7.2 1.4 1 0 0 1 1 1 0 Hsp90 protein Nucleoporin_N PF08801.6 KND89739.1 - 5.2e-77 259.3 0.0 7.6e-77 258.8 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KND89739.1 - 3.2e-73 247.2 3.1 4.4e-73 246.7 2.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Sedlin_N PF04628.8 KND89740.1 - 9.8e-18 64.2 0.0 1.2e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peptidase_M1 PF01433.15 KND89741.1 - 2.7e-70 237.4 0.0 3.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KND89741.1 - 4.3e-42 143.0 0.0 7.8e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KND89741.1 - 7.4e-19 68.0 0.3 1.3e-18 67.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF4522 PF15022.1 KND89741.1 - 0.0055 16.3 0.0 0.056 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4522) Peptidase_M61 PF05299.7 KND89741.1 - 0.29 11.1 2.0 1.3 9.0 1.4 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ten1 PF12658.2 KND89743.1 - 2.7e-30 104.6 0.0 3.1e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 KND89743.1 - 8.3e-07 28.5 0.0 8.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 KND89743.1 - 0.0074 16.1 0.1 0.019 14.8 0.1 1.6 1 1 0 1 1 1 1 Replication factor A protein 3 DUF952 PF06108.7 KND89744.1 - 5.4e-22 77.4 0.0 7.3e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Uds1 PF15456.1 KND89745.1 - 3.5e-35 120.6 3.6 3.5e-35 120.6 2.5 2.0 2 0 0 2 2 2 1 Up-regulated During Septation PXA PF02194.10 KND89746.1 - 2.4e-35 121.8 0.0 5e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KND89746.1 - 2.4e-19 69.5 0.0 7e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KND89746.1 - 4.8e-06 26.3 0.0 1.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PX domain Kinesin PF00225.18 KND89749.1 - 4.5e-111 370.7 0.0 4.5e-111 370.7 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 KND89749.1 - 1.6e-42 144.4 0.6 5.2e-42 142.8 0.0 2.2 2 0 0 2 2 2 1 Kinesin protein KIF1B PF12423.3 KND89749.1 - 2.2e-05 24.3 0.4 6.3e-05 22.9 0.3 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KND89749.1 - 0.00014 21.8 0.1 0.002 18.1 0.0 3.0 3 0 0 3 3 3 1 FHA domain PH PF00169.24 KND89749.1 - 0.00076 19.6 0.0 0.0031 17.6 0.0 2.1 1 0 0 1 1 1 1 PH domain OmpH PF03938.9 KND89749.1 - 6.8 6.6 22.8 2.3 8.1 11.9 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Med1 PF10744.4 KND89751.1 - 1.5e-37 129.2 0.0 6.5e-37 127.2 0.0 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Formyl_trans_N PF00551.14 KND89753.1 - 9.6e-22 77.3 0.0 1.7e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KND89753.1 - 4e-05 23.6 0.2 8.9e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain LIM PF00412.17 KND89755.1 - 2.3e-21 75.6 16.3 3.7e-11 42.9 2.7 2.9 3 0 0 3 3 3 2 LIM domain WRC PF08879.5 KND89755.1 - 0.11 12.1 1.0 0.92 9.2 0.1 2.4 2 0 0 2 2 2 0 WRC zinc_ribbon_2 PF13240.1 KND89755.1 - 9.2 5.9 10.7 26 4.4 2.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain DUF3405 PF11885.3 KND89756.1 - 2.6e-176 586.6 12.2 4e-176 586.1 8.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Pribosyltran PF00156.22 KND89757.1 - 6e-06 25.9 0.1 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_5 PF07994.7 KND89758.1 - 3.1e-113 378.1 0.5 3.8e-113 377.8 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KND89758.1 - 4.5e-32 110.2 2.3 2.9e-23 81.8 0.5 3.0 2 1 1 3 3 3 2 Myo-inositol-1-phosphate synthase MRC1 PF09444.5 KND89759.1 - 1.4e-38 132.4 15.7 1.4e-38 132.4 10.9 6.6 5 1 1 7 7 7 1 MRC1-like domain Nse4_C PF08743.5 KND89761.1 - 1.6e-32 111.3 0.0 3.4e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KND89761.1 - 2.4e-19 68.9 0.0 1.2e-18 66.7 0.0 2.2 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE BHD_2 PF10404.4 KND89762.1 - 0.041 14.2 1.9 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 MGC-24 PF05283.6 KND89762.1 - 3.5 7.3 6.7 5.1 6.8 4.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) PI3Ka PF00613.15 KND89763.1 - 5.2e-58 195.2 0.5 8.3e-58 194.6 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KND89763.1 - 8.3e-43 146.5 0.1 1.5e-41 142.4 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KND89763.1 - 1.1e-30 106.2 0.0 1.8e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 KND89763.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins DUF4336 PF14234.1 KND89764.1 - 3.7e-11 42.7 0.0 1.7e-07 30.7 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) ADH_zinc_N PF00107.21 KND89766.1 - 1.9e-11 43.6 0.1 4.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND89766.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MMR_HSR1 PF01926.18 KND89767.1 - 1.7e-13 50.5 0.0 3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KND89767.1 - 3.5e-05 23.0 0.1 5.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND89767.1 - 0.002 18.1 0.8 0.0036 17.2 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 KND89767.1 - 0.0025 17.1 0.2 0.0063 15.7 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KND89767.1 - 0.011 15.5 0.1 0.57 9.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.1 KND89767.1 - 0.017 15.2 0.7 5.2 7.2 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 KND89767.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KND89767.1 - 0.025 14.1 0.3 0.048 13.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KND89767.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin AIG1 PF04548.11 KND89767.1 - 0.039 13.0 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.22 KND89767.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Miro PF08477.8 KND89767.1 - 0.12 12.9 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 KND89767.1 - 0.17 12.6 2.0 0.37 11.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.16 KND89768.1 - 1.2e-44 152.9 15.6 1.4e-24 86.6 3.0 2.9 1 1 1 2 2 2 2 HCO3- transporter family ATP-synt_C PF00137.16 KND89769.1 - 1.6e-26 91.9 28.1 2.6e-15 56.0 5.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1282 PF06930.7 KND89769.1 - 3.4 7.2 7.9 1.4 8.5 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) CNH PF00780.17 KND89770.1 - 2.3e-82 276.5 0.0 8e-82 274.7 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KND89770.1 - 7.3e-43 145.7 0.0 2.1e-42 144.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KND89770.1 - 5.7e-33 114.2 0.0 1.1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KND89770.1 - 7.5e-15 54.4 0.0 1.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GPI2 PF06432.6 KND89771.1 - 6.9e-114 379.9 0.1 8.7e-114 379.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase 2-Hacid_dh_C PF02826.14 KND89773.1 - 1.2e-38 132.0 0.0 9.1e-29 99.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KND89773.1 - 0.001 19.0 0.0 0.0028 17.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding XdhC_C PF13478.1 KND89773.1 - 0.018 15.3 0.0 0.051 13.8 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.10 KND89773.1 - 0.046 13.5 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KND89773.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KND89773.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.1 KND89773.1 - 7.5 6.6 11.7 0.42 10.7 2.4 2.3 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain WD40 PF00400.27 KND89774.1 - 7.4e-12 44.6 14.2 7.4e-07 28.8 0.4 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat RWD PF05773.17 KND89774.1 - 0.00027 20.8 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KND89774.1 - 0.017 14.9 6.7 0.039 13.7 4.6 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.21 KND89775.1 - 2.5e-47 159.8 0.0 2.8e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND89775.1 - 7.6e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KND89775.1 - 0.0044 16.6 0.1 0.0081 15.8 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KND89775.1 - 0.046 13.6 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Mt_ATP-synt_D PF05873.7 KND89776.1 - 9.4e-17 61.1 2.7 1.3e-16 60.6 1.9 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Phage_GP20 PF06810.6 KND89776.1 - 0.45 9.9 5.8 0.22 10.9 0.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spectrin PF00435.16 KND89776.1 - 1.1 9.5 7.3 0.55 10.5 0.3 2.2 1 1 1 2 2 2 0 Spectrin repeat Ribosomal_L14e PF01929.12 KND89777.1 - 5.7e-27 93.8 4.0 7.6e-27 93.4 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Rhomboid_SP PF12595.3 KND89779.1 - 0.028 14.0 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Rhomboid serine protease NAC PF01849.13 KND89780.1 - 1.2e-26 91.9 0.3 1.5e-25 88.4 0.0 2.4 3 0 0 3 3 3 1 NAC domain UBA PF00627.26 KND89780.1 - 0.0021 17.8 0.2 0.0021 17.8 0.1 2.6 3 0 0 3 3 3 1 UBA/TS-N domain CENP-B_dimeris PF09026.5 KND89780.1 - 0.41 10.9 8.6 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.7 KND89780.1 - 4.6 6.4 13.4 1.1 8.4 2.2 2.5 2 1 1 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) BTV_NS2 PF04514.7 KND89780.1 - 4.7 6.0 7.3 1.7 7.4 1.4 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 KND89780.1 - 6 7.2 9.4 6.6 7.1 1.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 KND89780.1 - 9.7 5.8 16.2 3.7 7.2 1.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rad21_Rec8_N PF04825.8 KND89781.1 - 1.6e-26 92.4 0.0 2.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KND89781.1 - 0.00025 20.1 0.0 0.00093 18.3 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KND89781.1 - 0.0059 16.2 1.2 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein DUF2283 PF10049.4 KND89781.1 - 0.015 15.1 0.6 0.044 13.6 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Asp PF00026.18 KND89782.1 - 2e-55 188.2 2.5 2.9e-55 187.7 1.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND89782.1 - 5.6e-07 29.6 0.0 1.4e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND89782.1 - 0.001 19.5 0.7 1.2 9.6 0.0 3.7 3 1 0 3 3 3 1 Aspartyl protease RVP PF00077.15 KND89782.1 - 0.012 15.4 0.0 3.5 7.6 0.0 2.9 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KND89782.1 - 0.021 14.6 0.2 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KND89782.1 - 0.03 13.8 0.1 0.12 11.9 0.0 2.1 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal G-patch PF01585.18 KND89783.1 - 4.4e-10 39.1 2.9 9.9e-10 38.0 2.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KND89783.1 - 1.6e-06 27.8 1.6 5e-06 26.2 1.1 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KND89783.1 - 1.6e-05 23.9 3.3 3.4e-05 22.8 2.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RED_N PF07808.8 KND89783.1 - 0.014 14.6 5.3 0.023 13.9 3.7 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 KND89783.1 - 0.022 14.8 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 KND89783.1 - 0.11 12.1 0.3 21 4.8 0.0 3.6 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KND89783.1 - 0.27 10.3 4.7 0.54 9.4 3.2 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Oxysterol_BP PF01237.13 KND89784.1 - 3.1e-128 427.2 0.0 1.7e-127 424.8 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 KND89784.1 - 7e-19 67.9 0.0 9.5e-13 48.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND89784.1 - 4.1e-17 61.0 0.1 1.7e-06 27.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KND89784.1 - 1.1e-16 60.5 0.2 1.2e-09 38.0 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND89784.1 - 4.3e-15 55.7 0.0 3.5e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89784.1 - 4.2e-14 51.2 0.0 0.00013 21.8 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 KND89784.1 - 7.9e-11 42.0 0.6 1.6e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KND89784.1 - 5.5e-08 32.7 1.1 1.4e-07 31.4 0.8 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain HisKA PF00512.20 KND89784.1 - 0.054 13.4 0.4 0.42 10.6 0.1 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain 4HBT_3 PF13622.1 KND89785.1 - 3.6e-49 167.8 1.2 4.6e-49 167.4 0.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KND89785.1 - 4.7e-22 78.0 0.0 1.3e-11 44.2 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Ferric_reduct PF01794.14 KND89786.1 - 1e-17 64.4 4.5 1e-17 64.4 3.1 2.5 4 0 0 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KND89786.1 - 5.1e-14 52.4 0.0 9.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KND89786.1 - 1.5e-13 50.5 0.1 5.4e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KND89786.1 - 2.5e-05 24.8 0.0 0.072 13.6 0.0 2.8 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.16 KND89787.1 - 9.1e-19 68.0 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KND89787.1 - 0.0026 17.6 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MoaE PF02391.12 KND89788.1 - 4e-29 100.8 0.0 5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein RRM_1 PF00076.17 KND89790.1 - 3.6e-14 52.1 0.0 5.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND89790.1 - 2.1e-09 37.2 0.0 3.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND89790.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND89790.1 - 0.06 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Fasciclin PF02469.17 KND89791.1 - 1.4e-38 131.7 0.0 2.3e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_76 PF03663.9 KND89792.1 - 2.3e-153 510.9 20.1 3e-153 510.5 14.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cytochrom_B_N PF00033.14 KND89792.1 - 0.043 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KND89792.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Synaptobrevin PF00957.16 KND89793.1 - 1.1e-32 111.4 1.4 1.3e-32 111.2 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF619 PF04768.8 KND89794.1 - 1.3e-43 148.3 0.0 2.3e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 KND89794.1 - 2.9e-28 99.0 0.0 5.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.19 KND89794.1 - 5.7e-27 94.4 0.0 1.4e-26 93.1 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 KND89795.1 - 1.1e-23 83.5 0.0 1.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med17 PF10156.4 KND89796.1 - 1.9e-75 253.9 0.0 2.5e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex SNF2_N PF00176.18 KND89797.1 - 2e-61 207.4 0.0 3.1e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND89797.1 - 5.9e-12 45.2 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KND89797.1 - 2e-09 36.9 2.2 3.8e-09 36.0 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND89797.1 - 2.4e-08 33.5 3.7 5.1e-08 32.4 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND89797.1 - 5.7e-08 32.6 4.1 1.2e-07 31.6 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND89797.1 - 7.3e-07 28.8 4.0 1.6e-06 27.6 2.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KND89797.1 - 8.6e-07 28.6 4.2 1.6e-06 27.8 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KND89797.1 - 9.1e-06 25.3 1.6 2.2e-05 24.0 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KND89797.1 - 7.1e-05 22.6 4.6 0.00022 20.9 3.2 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KND89797.1 - 0.0044 16.5 2.5 0.018 14.5 1.9 2.0 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KND89797.1 - 0.027 13.9 3.3 0.074 12.5 2.3 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger SPT6_acidic PF14632.1 KND89797.1 - 0.043 13.9 6.9 0.12 12.5 4.8 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Baculo_RING PF05883.6 KND89797.1 - 0.046 13.5 1.6 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Baculo_IE-1 PF05290.6 KND89797.1 - 0.13 11.9 3.9 0.11 12.2 1.3 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Phosphodiest PF01663.17 KND89798.1 - 2.3e-89 300.2 0.5 3.3e-89 299.7 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KND89798.1 - 0.00042 19.5 0.0 0.043 12.9 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PGA2 PF07543.7 KND89798.1 - 0.53 10.0 5.0 1.3 8.8 3.5 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 PBP1_TM PF14812.1 KND89798.1 - 2.8 8.2 12.0 0.51 10.6 0.4 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myosin_head PF00063.16 KND89801.1 - 2.2e-247 822.5 0.0 2.2e-247 822.5 0.0 2.4 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KND89801.1 - 3.9e-20 71.2 280.7 3.6e-17 61.4 59.6 7.6 3 2 4 7 7 7 6 Myosin tail Myosin_N PF02736.14 KND89801.1 - 9.7e-06 25.1 0.2 2.2e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KND89801.1 - 0.00032 20.2 18.6 0.00032 20.2 12.9 11.9 1 1 6 8 8 8 2 Intermediate filament protein AAA_19 PF13245.1 KND89801.1 - 0.05 13.3 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain CNH PF00780.17 KND89802.1 - 3.1e-63 213.7 0.0 5.5e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KND89802.1 - 5e-33 114.4 0.2 7.7e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KND89802.1 - 1.8e-12 47.3 0.0 7.6e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KND89802.1 - 0.00016 21.8 0.0 0.00097 19.3 0.0 2.4 2 0 0 2 2 2 1 PH domain HgmA PF04209.8 KND89803.1 - 2.2e-129 431.5 0.1 2.5e-129 431.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ribosomal_L25p PF01386.14 KND89804.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L25p family MPC PF03650.8 KND89805.1 - 1.5e-30 105.5 2.6 9.5e-19 67.4 0.1 3.1 2 1 0 3 3 3 3 Uncharacterised protein family (UPF0041) FA_desaturase PF00487.19 KND89806.1 - 5.1e-17 62.1 21.4 5.1e-17 62.1 14.8 2.0 1 1 1 2 2 2 1 Fatty acid desaturase RseC_MucC PF04246.7 KND89806.1 - 0.05 13.1 0.3 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC 60KD_IMP PF02096.15 KND89806.1 - 0.069 12.8 0.4 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein DUF106 PF01956.11 KND89806.1 - 0.095 12.2 0.3 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1687 PF07955.6 KND89807.1 - 8.3e-16 58.1 0.8 5.9e-15 55.4 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) zf-C3H1 PF10650.4 KND89808.1 - 0.53 9.8 2.4 0.9 9.0 1.6 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain RTA1 PF04479.8 KND89809.1 - 3.2e-47 160.8 1.2 3.2e-47 160.8 0.8 1.4 1 1 1 2 2 2 1 RTA1 like protein SUR7 PF06687.7 KND89810.1 - 4.9e-30 104.6 7.2 6.1e-30 104.3 5.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KND89810.1 - 2.2e-06 27.4 6.0 2.2e-06 27.4 4.1 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.9 KND89810.1 - 1.2 8.9 7.4 0.81 9.5 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Fig1 PF12351.3 KND89810.1 - 2.1 8.1 9.2 0.76 9.6 3.9 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 BPL_LplA_LipB PF03099.14 KND89811.1 - 1.7e-06 28.0 0.0 6.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family PI3_PI4_kinase PF00454.22 KND89812.1 - 9.2e-48 162.7 0.0 1.7e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KND89812.1 - 1.6e-34 119.4 1.9 3.1e-34 118.5 1.3 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KND89812.1 - 5.6e-27 93.7 0.0 2.2e-26 91.8 0.0 2.2 1 0 0 1 1 1 1 UME (NUC010) domain zf-PARP PF00645.13 KND89812.1 - 3.7e-17 62.3 0.7 9.9e-17 60.9 0.5 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FATC PF02260.15 KND89812.1 - 1.3e-13 50.0 0.0 3.9e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 FATC domain HSP70 PF00012.15 KND89812.1 - 1.1e-11 43.3 0.0 1.1e-11 43.3 0.0 2.5 3 0 0 3 3 3 1 Hsp70 protein TPR_19 PF14559.1 KND89812.1 - 0.0016 18.7 2.4 0.0095 16.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND89812.1 - 0.91 10.3 7.2 14 6.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Atg14 PF10186.4 KND89813.1 - 0.38 9.6 8.9 0.77 8.6 6.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KND89813.1 - 3 5.5 7.3 4.2 5.1 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KND89813.1 - 5 6.6 15.0 8.6 5.9 10.4 1.3 1 0 0 1 1 1 0 IncA protein AIG2 PF06094.7 KND89814.1 - 6.9e-10 39.3 0.1 1.4e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KND89814.1 - 3e-06 27.2 0.1 0.0024 17.9 0.0 2.6 2 0 0 2 2 2 2 AIG2-like family Amidoligase_2 PF12224.3 KND89815.1 - 1.2e-19 70.9 0.0 1.8e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme CPSase_L_D2 PF02786.12 KND89816.1 - 4.3e-74 248.3 0.0 6.9e-74 247.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KND89816.1 - 1.5e-34 118.2 0.0 3.5e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KND89816.1 - 1.2e-31 109.0 0.0 2.2e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KND89816.1 - 1.5e-17 63.9 0.1 5.4e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KND89816.1 - 3.7e-16 58.5 2.6 1.6e-15 56.4 1.8 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KND89816.1 - 4.2e-16 58.6 0.0 7.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KND89816.1 - 1.3e-09 37.5 0.1 0.001 18.6 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KND89816.1 - 8.2e-08 31.8 0.0 1.8e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KND89816.1 - 5.5e-07 29.0 0.0 1.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KND89816.1 - 1.7e-05 24.2 0.2 0.12 11.6 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 KND89816.1 - 7.8e-05 22.9 0.0 0.16 12.3 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KND89816.1 - 0.0026 17.6 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Nairovirus_M PF07948.6 KND89816.1 - 0.017 13.2 0.0 0.026 12.6 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like HlyD_2 PF12700.2 KND89816.1 - 0.15 11.1 0.2 4.1 6.4 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 KND89816.1 - 0.16 11.6 0.6 0.41 10.3 0.2 1.9 2 0 0 2 2 2 0 Glycine cleavage H-protein Pyridox_oxidase PF01243.15 KND89817.1 - 2e-12 46.9 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 KND89817.1 - 0.0063 14.5 0.0 0.0071 14.4 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Pyridox_ox_2 PF12900.2 KND89817.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.13 KND89818.1 - 8.2e-45 152.7 0.0 1.2e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 KND89819.1 - 1.6e-50 171.6 0.0 2.6e-47 161.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND89819.1 - 1.7e-30 105.9 0.0 4.6e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KND89819.1 - 0.00046 19.2 0.0 0.00071 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KND89819.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Glyco_hydro_35 PF01301.14 KND89821.1 - 3.1e-82 276.4 0.0 4.8e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KND89821.1 - 1.3e-57 194.1 0.1 2e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KND89821.1 - 3.1e-49 165.8 1.3 7.3e-28 97.0 0.4 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KND89821.1 - 1.3e-23 82.2 0.0 2.4e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Dabb PF07876.7 KND89823.1 - 9.4e-12 45.2 0.1 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain YIF1 PF03878.10 KND89824.1 - 1.8e-69 233.5 2.9 2.1e-66 223.5 0.7 2.0 1 1 1 2 2 2 2 YIF1 Yip1 PF04893.12 KND89824.1 - 0.14 11.6 6.1 0.44 10.0 4.2 1.8 1 1 0 1 1 1 0 Yip1 domain PPTA PF01239.17 KND89825.1 - 0.18 11.1 1.8 0.44 9.9 1.3 1.7 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat PAM2 PF07145.10 KND89826.1 - 0.0021 17.4 7.3 0.1 12.1 0.9 3.7 3 0 0 3 3 3 2 Ataxin-2 C-terminal region T2SF PF00482.18 KND89826.1 - 1.2 9.1 3.0 8.5 6.3 2.1 2.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F VHL PF01847.11 KND89827.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein SRP-alpha_N PF04086.8 KND89828.1 - 2.5e-72 243.5 0.0 3.7e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KND89828.1 - 3.7e-53 179.8 0.3 6.2e-53 179.1 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 KND89828.1 - 1.8e-05 23.6 0.0 3.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KND89828.1 - 2.1e-05 24.0 0.3 5.2e-05 22.7 0.2 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 KND89828.1 - 0.00039 20.4 0.1 0.002 18.2 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.7 KND89828.1 - 0.005 15.9 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 KND89828.1 - 0.007 16.0 0.3 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KND89828.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KND89828.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND89828.1 - 0.035 14.2 0.1 0.61 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KND89828.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KND89828.1 - 0.083 13.2 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Amidohydro_5 PF13594.1 KND89830.1 - 4.7e-09 35.9 0.1 6.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KND89830.1 - 0.0022 17.2 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KND89830.1 - 0.006 16.6 0.0 0.0077 16.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KND89830.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family Mid2 PF04478.7 KND89831.1 - 1.3e-06 27.9 4.6 1.3e-06 27.9 3.2 2.6 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor DUF533 PF04391.7 KND89831.1 - 0.13 11.6 0.1 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) CRA PF06589.6 KND89831.1 - 0.38 10.0 0.1 0.38 10.0 0.0 2.5 3 1 0 3 3 3 0 Circumsporozoite-related antigen (CRA) AA_permease PF00324.16 KND89832.1 - 1.1e-120 403.2 47.6 1.3e-120 402.9 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND89832.1 - 7.2e-30 103.8 52.1 9.3e-30 103.5 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 KND89832.1 - 0.045 13.3 0.5 0.1 12.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Acetyltransf_1 PF00583.19 KND89833.1 - 0.00029 20.8 0.0 0.0049 16.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND89833.1 - 0.002 18.2 0.1 0.005 16.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND89833.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Thioredoxin PF00085.15 KND89834.1 - 5.2e-27 93.5 0.0 7.3e-27 93.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KND89834.1 - 4.3e-06 26.7 0.0 8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KND89834.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KND89834.1 - 0.00023 21.3 0.1 0.0013 18.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KND89834.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 KND89834.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KND89834.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Methyltrn_RNA_3 PF02598.12 KND89835.1 - 6.6e-84 281.6 0.0 7.7e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase MFS_1 PF07690.11 KND89836.1 - 1e-48 165.9 36.5 1e-48 165.9 25.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND89836.1 - 7.1e-13 47.9 35.3 1.2e-12 47.2 11.6 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KND89836.1 - 0.00067 17.8 13.0 0.0063 14.6 0.1 3.1 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KND89836.1 - 0.0038 15.3 13.4 0.0088 14.2 9.3 1.7 1 1 0 1 1 1 1 Transmembrane secretion effector Pyr_redox PF00070.22 KND89837.1 - 9.1e-14 51.6 0.0 1.3e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND89837.1 - 2e-12 47.4 0.0 1.3e-11 44.7 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND89837.1 - 5.1e-09 35.5 0.0 1.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KND89837.1 - 2.7e-08 34.1 0.1 9.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND89837.1 - 0.017 14.0 0.0 0.42 9.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 KND89837.1 - 0.036 12.9 0.1 0.55 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND89837.1 - 0.073 13.1 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TP_methylase PF00590.15 KND89838.1 - 1.7e-44 152.0 0.7 3.1e-44 151.1 0.5 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KND89838.1 - 3e-14 53.1 0.0 5.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KND89838.1 - 7.4e-09 34.7 0.0 6.7e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KND89838.1 - 0.00016 20.5 0.0 0.00035 19.4 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rsm22 PF09243.5 KND89839.1 - 3.4e-30 105.0 0.0 4.4e-29 101.3 0.0 2.8 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Fungal_trans PF04082.13 KND89839.1 - 1.5e-09 37.1 0.0 2.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89839.1 - 6.5e-08 32.3 7.9 1.2e-07 31.4 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_18 PF12847.2 KND89839.1 - 0.035 14.6 0.0 0.15 12.6 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KND89839.1 - 0.068 13.6 0.0 0.23 11.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain RAB3GAP2_N PF14655.1 KND89839.1 - 0.59 9.0 1.6 1.1 8.2 1.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus adh_short PF00106.20 KND89840.1 - 2e-07 31.0 0.8 5.4e-07 29.6 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase ACP_syn_III_C PF08541.5 KND89840.1 - 0.1 12.6 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Lyase_1 PF00206.15 KND89841.1 - 5.4e-105 351.0 0.0 6.4e-105 350.7 0.0 1.1 1 0 0 1 1 1 1 Lyase Pal1 PF08316.6 KND89842.1 - 1.1e-47 161.9 0.9 1.1e-47 161.9 0.6 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein Pex14_N PF04695.8 KND89843.1 - 0.2 11.7 5.8 1.5 8.8 0.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 KND89844.1 - 2.7e-38 131.6 0.0 3.4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89844.1 - 1.5e-13 50.4 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND89844.1 - 2.9e-05 23.9 0.0 0.0023 17.6 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KND89844.1 - 0.075 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Exo_endo_phos PF03372.18 KND89845.1 - 5.8e-14 52.6 9.3 1.5e-13 51.2 6.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RabGAP-TBC PF00566.13 KND89846.1 - 1.6e-45 155.1 0.0 2.6e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KND89846.1 - 0.00091 18.9 0.1 0.2 11.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KND89846.1 - 0.0012 18.8 0.1 0.016 15.3 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KND89846.1 - 0.043 13.1 0.0 1.7 8.1 0.1 3.2 2 0 0 2 2 2 0 EF hand NUDIX PF00293.23 KND89847.1 - 1.1e-09 38.0 0.3 2.6e-09 36.8 0.2 1.6 1 1 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.1 KND89850.1 - 1.9e-25 90.0 0.2 2.9e-25 89.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND89850.1 - 2.7e-22 79.4 0.1 2.4e-21 76.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND89850.1 - 1.4e-12 47.6 0.1 1.3e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 KR domain Acyl-CoA_dh_1 PF00441.19 KND89851.1 - 8.2e-40 136.3 1.2 8.2e-40 136.3 0.9 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND89851.1 - 2.9e-32 111.5 0.1 6.7e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KND89851.1 - 1.3e-18 66.2 0.1 2.9e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KND89851.1 - 9.9e-12 45.2 0.2 9.9e-12 45.2 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KND89851.1 - 0.0022 17.4 0.1 0.0089 15.4 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NST1 PF13945.1 KND89852.1 - 1.6 8.7 17.2 1.4 8.9 1.1 3.1 2 1 0 2 2 2 0 Salt tolerance down-regulator DUF1752 PF08550.5 KND89853.1 - 0.00073 19.0 1.5 0.0015 18.0 1.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF718 PF05336.8 KND89854.1 - 3.2e-34 116.9 0.3 3.8e-34 116.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) QCR10 PF09796.4 KND89855.1 - 1.3 8.6 3.5 13 5.4 0.1 2.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Carboxyl_trans PF01039.17 KND89856.1 - 7.9e-143 476.3 0.3 1e-142 475.9 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KND89856.1 - 0.012 14.7 0.3 0.24 10.5 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) hEGF PF12661.2 KND89857.1 - 0.012 15.6 2.4 0.033 14.2 1.6 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF PHD PF00628.24 KND89858.1 - 2.2e-09 36.8 1.6 2.2e-09 36.8 1.1 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KND89858.1 - 0.024 13.9 2.8 0.039 13.2 1.9 1.4 1 0 0 1 1 1 0 PHD-finger TIMELESS_C PF05029.8 KND89859.1 - 2 7.2 6.5 1.7 7.5 3.6 1.4 2 0 0 2 2 2 0 Timeless protein C terminal region TFIIS_C PF01096.13 KND89860.1 - 1.4e-20 72.6 2.0 1.4e-20 72.6 1.4 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zf-Nse PF11789.3 KND89860.1 - 0.092 12.2 0.0 0.71 9.4 0.0 2.2 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Baculo_LEF5_C PF11792.3 KND89860.1 - 0.15 11.4 1.2 0.21 11.0 0.0 1.8 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain RNA_POL_M_15KD PF02150.11 KND89860.1 - 0.49 10.1 3.6 0.69 9.6 0.0 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit C1_3 PF07649.7 KND89860.1 - 0.52 10.4 0.2 0.52 10.4 0.2 2.1 2 0 0 2 2 2 0 C1-like domain DUF4379 PF14311.1 KND89860.1 - 0.87 9.4 4.7 0.66 9.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) zinc_ribbon_4 PF13717.1 KND89860.1 - 6.1 6.6 7.5 6.5 6.5 0.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KND89860.1 - 6.2 6.5 7.1 5.1 6.7 0.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Ank PF00023.25 KND89862.1 - 1.4e-07 30.9 0.0 0.011 15.5 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KND89862.1 - 1.6e-06 28.3 0.0 3.8e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND89862.1 - 4.8e-06 26.9 0.0 1.7 9.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND89862.1 - 0.00011 22.3 0.0 0.41 10.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND89862.1 - 0.00053 19.9 1.1 1.1 9.7 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Thaumatin PF00314.12 KND89863.1 - 1.4e-69 233.7 7.6 1.8e-69 233.4 5.3 1.1 1 0 0 1 1 1 1 Thaumatin family HSP70 PF00012.15 KND89864.1 - 4e-11 41.5 0.2 1.2e-09 36.6 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KND89864.1 - 0.0039 16.8 0.1 0.009 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KND89864.1 - 0.018 13.6 0.1 0.095 11.2 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein DUF791 PF05631.9 KND89865.1 - 1.8e-61 207.8 7.2 2.5e-61 207.3 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KND89865.1 - 3.9e-14 52.1 24.8 1.7e-13 50.0 17.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.16 KND89865.1 - 0.16 11.8 2.4 2.4 8.0 0.0 3.6 3 0 0 3 3 3 0 Gram positive anchor DUF4131 PF13567.1 KND89865.1 - 6.7 6.0 10.6 5.7 6.3 2.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Acetyltransf_1 PF00583.19 KND89866.1 - 3.6e-07 30.1 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND89866.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexokinase_2 PF03727.11 KND89867.1 - 9.9e-64 214.8 0.0 1.9e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KND89867.1 - 6.5e-61 205.2 0.0 1.2e-60 204.3 0.0 1.5 1 0 0 1 1 1 1 Hexokinase adh_short PF00106.20 KND89867.1 - 0.021 14.7 0.7 0.054 13.3 0.5 1.7 1 0 0 1 1 1 0 short chain dehydrogenase CFEM PF05730.6 KND89868.1 - 5.1e-10 39.0 12.6 1e-09 38.0 8.7 1.5 1 0 0 1 1 1 1 CFEM domain DUF4156 PF13698.1 KND89868.1 - 0.047 13.5 1.9 0.077 12.8 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) Metallophos_2 PF12850.2 KND89869.1 - 7.5e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND89869.1 - 3.4e-10 39.6 0.3 4.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Aldolase_II PF00596.16 KND89869.1 - 0.059 12.9 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Sgf11 PF08209.6 KND89870.1 - 0.026 13.8 2.6 0.026 13.8 1.8 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ORC6 PF05460.8 KND89870.1 - 0.53 9.3 11.4 1.1 8.2 7.9 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DLH PF01738.13 KND89872.1 - 4.4e-12 45.7 0.1 5.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND89872.1 - 0.043 13.5 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PFK PF00365.15 KND89873.1 - 3.2e-163 541.4 0.9 3.9e-117 390.2 1.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 KND89873.1 - 0.014 14.9 2.1 0.033 13.7 1.5 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif TgMIC1 PF11476.3 KND89873.1 - 0.13 11.7 1.4 3.9 7.0 0.1 3.0 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Glyco_hydro_16 PF00722.16 KND89874.1 - 1.9e-41 141.4 1.5 2.5e-41 140.9 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 YHYH PF14240.1 KND89874.1 - 0.02 14.5 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 YHYH protein SAICAR_synt PF01259.13 KND89875.1 - 1.4e-79 266.7 0.0 1.7e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Aminotran_1_2 PF00155.16 KND89876.1 - 5.9e-47 160.3 0.0 6.9e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KND89876.1 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 KND89876.1 - 0.063 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF865 PF05906.6 KND89876.1 - 0.092 12.3 0.6 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Fungal_trans PF04082.13 KND89877.1 - 4.5e-14 51.9 0.1 6.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89877.1 - 0.016 15.0 7.8 0.032 14.1 5.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KND89877.1 - 3.2 5.8 20.6 4.8 5.2 14.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HMGL-like PF00682.14 KND89879.1 - 1.4e-62 211.4 0.0 1.9e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KND89879.1 - 3.2e-24 85.2 0.0 6.9e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain HEAT PF02985.17 KND89880.1 - 1.2e-12 46.7 18.4 0.022 14.8 0.0 10.3 12 1 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 KND89880.1 - 4.7e-12 46.0 13.2 7.3e-07 29.4 0.0 8.6 7 2 3 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 KND89880.1 - 2.2e-11 43.8 22.3 4.1e-05 23.7 0.0 7.6 3 2 4 7 7 7 4 HEAT repeats CLASP_N PF12348.3 KND89880.1 - 4.1e-07 29.6 4.2 0.0064 15.8 0.0 5.1 4 2 1 6 6 6 2 CLASP N terminal IBN_N PF03810.14 KND89880.1 - 8.7e-06 25.5 1.6 8.7e-06 25.5 1.1 5.1 4 1 1 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KND89880.1 - 9.7e-06 25.5 9.4 0.17 11.8 0.1 6.6 5 2 2 7 7 7 2 Exportin 1-like protein HEAT_PBS PF03130.11 KND89880.1 - 0.019 15.3 0.1 76 4.2 0.1 4.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Glyco_hydro_75 PF07335.6 KND89881.1 - 8.7e-46 155.6 0.1 1e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 zf-DHHC PF01529.15 KND89883.1 - 3.1e-39 134.1 0.7 6.6e-39 133.0 0.5 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase ABC_tran PF00005.22 KND89884.1 - 7.5e-49 165.5 0.3 2.3e-26 92.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND89884.1 - 5.3e-17 62.7 0.3 2.3e-07 31.1 0.2 3.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KND89884.1 - 2e-14 53.3 0.0 4.3e-06 26.1 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND89884.1 - 3.3e-08 34.0 0.1 0.00038 20.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND89884.1 - 1.7e-07 30.6 0.3 0.0082 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KND89884.1 - 2e-07 30.4 0.0 0.031 13.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 KND89884.1 - 2e-07 30.9 0.0 0.0071 16.2 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KND89884.1 - 2.3e-07 31.6 0.0 0.0075 17.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 KND89884.1 - 3.8e-07 29.6 0.2 2.1e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 KND89884.1 - 2.4e-06 26.8 0.0 0.0083 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KND89884.1 - 7.5e-06 26.4 0.1 0.011 16.1 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KND89884.1 - 7.7e-06 26.0 0.3 0.25 11.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KND89884.1 - 1.4e-05 25.1 0.0 0.00077 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KND89884.1 - 1.4e-05 24.8 0.0 0.32 10.9 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KND89884.1 - 3.8e-05 23.2 4.0 0.37 10.1 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 KND89884.1 - 8.5e-05 22.4 0.0 0.75 9.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KND89884.1 - 0.00029 20.5 0.1 0.39 10.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KND89884.1 - 0.00049 20.4 0.1 0.053 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KND89884.1 - 0.0011 18.8 1.3 0.37 10.5 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 KND89884.1 - 0.0015 18.6 0.1 3 8.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 KND89884.1 - 0.0016 18.2 0.0 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family NACHT PF05729.7 KND89884.1 - 0.002 17.8 0.4 1 8.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KND89884.1 - 0.003 16.3 0.1 0.72 8.5 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_13 PF13166.1 KND89884.1 - 0.0034 15.9 0.1 1.6 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND89884.1 - 0.0052 16.1 0.0 4.9 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KND89884.1 - 0.0073 16.5 0.0 4.9 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KND89884.1 - 0.0085 15.5 0.0 0.92 8.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 KND89884.1 - 0.011 16.0 3.7 2.1 8.6 0.0 3.9 2 1 2 4 4 3 0 HEAT repeats AAA_30 PF13604.1 KND89884.1 - 0.014 14.9 0.9 6.9 6.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KND89884.1 - 0.019 14.9 1.1 2.4 8.1 0.1 3.4 3 0 0 3 3 3 0 AAA ATPase domain CLASP_N PF12348.3 KND89884.1 - 0.022 14.1 0.0 0.46 9.7 0.0 2.6 3 0 0 3 3 3 0 CLASP N terminal AAA_14 PF13173.1 KND89884.1 - 0.024 14.5 0.0 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KND89884.1 - 0.035 11.4 1.4 2.9 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Arch_ATPase PF01637.13 KND89884.1 - 0.054 13.1 0.0 8.1 6.0 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase DUF815 PF05673.8 KND89884.1 - 0.066 12.1 0.1 3.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 KND89884.1 - 0.094 12.1 0.2 16 4.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 KND89884.1 - 0.11 11.9 0.2 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 MutS domain V HEAT PF02985.17 KND89884.1 - 0.13 12.3 2.0 1.4e+02 2.9 0.0 5.5 6 0 0 6 6 4 0 HEAT repeat Glyco_hydro_16 PF00722.16 KND89885.1 - 3.4e-18 65.5 3.6 5.8e-18 64.8 2.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TYW3 PF02676.9 KND89886.1 - 3.4e-63 212.4 0.0 4.1e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PAPS_reduct PF01507.14 KND89887.1 - 2e-41 141.7 0.0 2.6e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 KND89888.1 - 5.2e-19 69.1 0.1 7.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND89888.1 - 2.3e-12 47.7 2.8 3.2e-11 44.0 0.2 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND89888.1 - 1.5e-09 37.8 1.2 1.7e-07 31.0 0.1 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND89888.1 - 8.2e-06 26.1 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KND89888.1 - 0.0012 17.9 0.2 0.0017 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acid_PPase PF12689.2 KND89888.1 - 0.08 12.5 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Acid Phosphatase KOW PF00467.24 KND89888.1 - 0.13 11.9 0.5 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 KOW motif Gram_pos_anchor PF00746.16 KND89889.1 - 0.072 12.9 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Gram positive anchor Ferric_reduct PF01794.14 KND89890.1 - 2e-21 76.3 8.2 2e-21 76.3 5.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KND89890.1 - 1.1e-17 64.4 0.0 2.9e-11 43.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KND89890.1 - 3.4e-09 36.5 0.0 2e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain DUF1690 PF07956.6 KND89891.1 - 1.5e-30 106.0 1.3 1.8e-30 105.7 0.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lzipper-MIP1 PF14389.1 KND89891.1 - 0.00039 20.4 1.9 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 TTKRSYEDQ PF10212.4 KND89891.1 - 0.0071 15.3 0.1 0.0076 15.2 0.1 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Matrilin_ccoil PF10393.4 KND89891.1 - 0.24 10.7 2.3 4.4 6.7 0.3 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin SNase PF00565.12 KND89892.1 - 7.9e-66 219.1 0.5 2.2e-16 60.0 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KND89892.1 - 1.7e-21 76.3 0.0 3.8e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KND89892.1 - 0.044 12.8 0.0 0.044 12.8 0.0 1.9 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) Wbp11 PF09429.5 KND89892.1 - 0.047 13.6 0.4 0.047 13.6 0.3 2.7 3 0 0 3 3 3 0 WW domain binding protein 11 Transaldolase PF00923.14 KND89893.1 - 4e-92 308.4 1.1 4.9e-92 308.1 0.8 1.0 1 0 0 1 1 1 1 Transaldolase p450 PF00067.17 KND89894.1 - 3.2e-61 207.2 0.0 3.9e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sod_Cu PF00080.15 KND89895.1 - 1.8e-46 157.8 3.5 2.1e-46 157.5 2.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pet191_N PF10203.4 KND89896.1 - 4.5e-28 97.0 5.0 5.9e-28 96.7 3.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 KND89896.1 - 0.078 12.6 0.4 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain Cmc1 PF08583.5 KND89896.1 - 1.2 8.9 4.5 4.2 7.2 1.4 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydro_lipase PF04083.11 KND89897.1 - 1e-20 72.8 0.0 2.1e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KND89897.1 - 3.3e-18 66.1 0.1 3.6e-17 62.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND89897.1 - 9.1e-09 35.5 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND89897.1 - 2.4e-05 24.1 0.0 7.9e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KND89897.1 - 0.00061 19.2 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Metallophos PF00149.23 KND89898.1 - 1e-10 41.3 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND89898.1 - 2.9e-09 36.9 0.0 5.4e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VARLMGL PF14383.1 KND89898.1 - 0.006 15.7 0.3 0.026 13.6 0.2 2.2 1 0 0 1 1 1 1 DUF761-associated sequence motif Peptidase_C12 PF01088.16 KND89900.1 - 2.8e-57 193.3 0.0 3.4e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MIP PF00230.15 KND89902.1 - 6.8e-25 87.8 8.3 8.8e-25 87.4 5.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_18 PF00704.23 KND89903.1 - 6.5e-15 55.4 1.8 8.2e-14 51.8 1.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Hormone_4 PF00220.12 KND89903.1 - 0.016 14.7 1.6 11 5.9 0.1 3.7 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Rifin_STEVOR PF02009.11 KND89903.1 - 0.12 11.9 2.6 0.21 11.2 1.8 1.3 1 0 0 1 1 1 0 Rifin/stevor family Macoilin PF09726.4 KND89903.1 - 4.3 5.4 13.1 5.6 5.1 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Plasmodium_Vir PF05795.6 KND89903.1 - 4.5 6.3 7.2 8.9 5.4 5.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2413 PF10310.4 KND89903.1 - 10 4.8 14.5 14 4.3 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) ETS_PEA3_N PF04621.8 KND89904.1 - 0.022 13.9 0.4 0.022 13.9 0.3 3.1 1 1 2 3 3 3 0 PEA3 subfamily ETS-domain transcription factor N terminal domain DUF3433 PF11915.3 KND89905.1 - 3.3e-29 100.8 22.9 4.9e-27 93.9 1.8 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pirin PF02678.11 KND89906.1 - 4.1e-26 90.9 2.0 1.3e-25 89.3 1.4 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KND89906.1 - 0.0004 19.8 3.0 0.032 13.7 0.4 3.1 2 1 0 2 2 2 2 Cupin domain Cupin_7 PF12973.2 KND89906.1 - 0.095 12.5 0.1 14 5.5 0.0 2.4 2 0 0 2 2 2 0 ChrR Cupin-like domain ALO PF04030.9 KND89907.1 - 4.2e-90 301.8 1.1 5.9e-90 301.3 0.7 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KND89907.1 - 4.1e-30 104.0 0.1 5.6e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain CN_hydrolase PF00795.17 KND89908.1 - 1.6e-32 112.3 0.0 2.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SSF PF00474.12 KND89909.1 - 3.8e-24 85.0 27.4 5.7e-24 84.5 19.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Pro_isomerase PF00160.16 KND89910.1 - 5.3e-48 163.1 0.0 6.4e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PI-PLC-X PF00388.14 KND89913.1 - 8.9e-56 187.3 0.0 1.5e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KND89913.1 - 5.4e-34 116.6 0.1 9.5e-34 115.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KND89913.1 - 0.003 17.5 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like ACPS PF01648.15 KND89914.1 - 3.4e-10 39.7 0.0 7.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.8 KND89915.1 - 2.8e-47 161.6 5.8 1.3e-46 159.3 4.0 2.0 1 1 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.12 KND89915.1 - 0.025 13.4 0.4 0.11 11.2 0.2 2.1 2 0 0 2 2 2 0 Presenilin Glyco_hydro_16 PF00722.16 KND89916.1 - 5.1e-11 42.1 0.0 8.3e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KND89916.1 - 0.099 10.7 0.0 0.23 9.5 0.0 1.5 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) ketoacyl-synt PF00109.21 KND89917.1 - 4.1e-72 242.7 0.0 9.2e-72 241.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KND89917.1 - 9.1e-52 175.3 0.1 9.1e-52 175.3 0.1 2.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KND89917.1 - 4.8e-51 173.9 1.8 8.6e-51 173.1 0.3 1.9 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KND89917.1 - 6.5e-47 160.1 0.0 1.3e-46 159.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KND89917.1 - 1.1e-38 132.8 1.1 2.4e-38 131.7 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND89917.1 - 3.7e-35 120.3 0.3 1.6e-34 118.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KND89917.1 - 3.8e-07 29.7 0.1 1.7e-06 27.6 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND89917.1 - 5.3e-06 26.1 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KND89917.1 - 0.0016 18.6 0.1 0.005 17.0 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KND89917.1 - 0.0081 15.1 0.1 0.022 13.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 KND89918.1 - 4.9e-27 94.5 44.3 2.4e-21 75.8 11.7 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily Annexin PF00191.15 KND89919.1 - 4.5e-20 71.3 0.4 4.1e-06 26.5 0.0 4.6 4 0 0 4 4 4 4 Annexin zf-FCS PF06467.9 KND89919.1 - 0.15 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif GidB PF02527.10 KND89920.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.1 KND89921.1 - 1.8e-20 73.2 0.0 3.3e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND89921.1 - 8e-11 42.2 0.0 2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89921.1 - 7.6e-09 35.3 0.0 4e-07 29.7 0.0 2.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89921.1 - 1.6e-08 35.1 0.0 1.4e-07 32.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89921.1 - 2.2e-08 34.4 0.0 2.1e-07 31.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89921.1 - 1.4e-06 28.5 0.0 2.6e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND89921.1 - 0.00021 21.3 0.1 0.023 14.7 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND89921.1 - 0.0004 19.5 0.0 0.00079 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KND89921.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KND89921.1 - 0.039 13.0 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KND89921.1 - 0.078 12.3 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.15 KND89921.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KND89922.1 - 2.2e-33 115.4 0.0 2.9e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KND89922.1 - 7.3e-05 23.3 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND89922.1 - 0.00035 20.3 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND89922.1 - 0.12 12.9 0.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_C1_2 PF03051.10 KND89924.1 - 2.6e-148 494.1 0.0 3e-148 493.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KND89924.1 - 7.8e-07 29.1 0.0 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease eIF-5a PF01287.15 KND89925.1 - 0.00054 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF3441 PF11923.3 KND89926.1 - 2.1e-36 123.9 0.0 2.1e-36 123.9 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KND89926.1 - 8.7e-29 100.3 18.2 8.7e-29 100.3 12.6 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KND89926.1 - 1.3e-22 79.4 0.0 3.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Tektin PF03148.9 KND89927.1 - 0.035 12.6 6.0 0.35 9.3 0.2 2.1 1 1 1 2 2 2 0 Tektin family DUF3294 PF07957.6 KND89927.1 - 0.062 12.8 4.8 0.093 12.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DUF2205 PF10224.4 KND89927.1 - 0.067 12.7 0.4 0.067 12.7 0.3 2.1 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) FMO-like PF00743.14 KND89928.1 - 3e-12 45.5 0.0 2.4e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND89928.1 - 1.2e-10 41.8 0.0 2.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND89928.1 - 1.9e-08 34.2 0.1 3.7e-07 30.0 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KND89928.1 - 5e-07 29.6 0.0 3.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KND89928.1 - 7e-07 28.4 0.0 2.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KND89928.1 - 0.00059 19.7 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND89928.1 - 0.081 12.0 0.5 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Thi4 family hDGE_amylase PF14701.1 KND89929.1 - 1.8e-173 577.3 0.0 2.4e-173 576.9 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KND89929.1 - 3.7e-115 384.6 0.3 8.9e-115 383.3 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KND89929.1 - 1.1e-85 286.9 0.0 1.9e-85 286.1 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KND89929.1 - 2.4e-27 94.6 0.0 5.8e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KND89929.1 - 6.1e-05 22.5 0.1 0.38 10.1 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF221 PF02714.10 KND89932.1 - 5.3e-86 288.4 21.1 8.8e-86 287.7 14.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND89932.1 - 3.1e-41 140.5 0.1 3.1e-41 140.5 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KND89932.1 - 5.5e-24 84.4 0.9 1e-23 83.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF258 PF03193.11 KND89933.1 - 0.18 10.9 1.1 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MFS_1 PF07690.11 KND89935.1 - 3e-42 144.6 34.3 3e-42 144.6 23.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND89935.1 - 4.7e-10 38.2 3.8 7.6e-10 37.6 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 2-Hacid_dh_C PF02826.14 KND89936.1 - 6.6e-56 188.2 0.0 9.5e-56 187.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND89936.1 - 4.9e-32 110.2 0.0 5.7e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KND89936.1 - 1.2e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KND89936.1 - 0.00021 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KND89936.1 - 0.00088 18.6 0.0 0.0038 16.6 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 KND89936.1 - 0.0046 16.5 1.4 0.37 10.3 0.2 2.3 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.14 KND89936.1 - 0.0064 15.1 0.0 0.0093 14.6 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase XdhC_C PF13478.1 KND89936.1 - 0.026 14.8 0.0 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain ThiF PF00899.16 KND89936.1 - 0.043 13.6 4.4 11 5.8 0.0 3.4 3 1 1 4 4 4 0 ThiF family 3HCDH_N PF02737.13 KND89936.1 - 0.051 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KND89936.1 - 0.07 13.5 0.0 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CoA_binding_2 PF13380.1 KND89936.1 - 0.073 13.2 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain GFO_IDH_MocA PF01408.17 KND89936.1 - 0.1 13.1 1.4 14 6.2 0.0 2.8 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 KND89936.1 - 0.23 11.5 3.4 1.7 8.7 0.8 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IBN_N PF03810.14 KND89937.1 - 4.9e-09 35.9 0.2 7.8e-08 32.1 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KND89937.1 - 0.025 14.5 0.0 0.59 10.0 0.0 3.0 2 0 0 2 2 2 0 Exportin 1-like protein Transp_cyt_pur PF02133.10 KND89938.1 - 3e-152 507.2 38.0 3.5e-152 506.9 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MTP18 PF10558.4 KND89939.1 - 1.6e-68 229.3 0.2 1.9e-68 229.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Photo_RC PF00124.14 KND89939.1 - 0.075 12.0 0.2 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein zf-AN1 PF01428.11 KND89940.1 - 4.6e-24 84.0 22.7 2.4e-12 46.5 4.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Remorin_C PF03763.8 KND89940.1 - 0.011 15.3 7.9 0.023 14.2 5.5 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region Transp_Tc5_C PF04236.10 KND89940.1 - 0.037 14.2 16.3 0.074 13.2 2.6 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.16 KND89940.1 - 0.55 10.1 21.3 0.18 11.7 3.4 2.8 2 1 0 2 2 2 0 IBR domain Rad4 PF03835.10 KND89941.1 - 3.1e-28 97.9 1.9 2.3e-27 95.1 1.3 2.4 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KND89941.1 - 4.9e-25 87.0 0.2 1.1e-24 85.8 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KND89941.1 - 6.2e-17 60.8 0.2 1.5e-16 59.5 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KND89941.1 - 2.3e-11 43.8 2.0 1e-10 41.7 0.0 3.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KND89941.1 - 0.00027 21.1 0.0 0.0019 18.3 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF913 PF06025.7 KND89941.1 - 0.17 10.5 1.4 0.35 9.5 1.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) IBR PF01485.16 KND89942.1 - 0.009 15.8 9.8 0.009 15.8 6.8 3.6 2 1 1 3 3 3 2 IBR domain DUF2036 PF09724.4 KND89944.1 - 2.1e-06 27.1 0.0 2.4e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) HORMA PF02301.13 KND89945.1 - 3.4e-16 59.3 0.0 4.3e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.3 KND89946.1 - 1.1e-25 90.0 0.0 1.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KND89946.1 - 9.7e-17 61.3 17.1 9.7e-17 61.3 11.8 2.4 2 1 0 2 2 2 1 PI31 proteasome regulator SLX9 PF15341.1 KND89947.1 - 2.4e-33 115.1 7.6 5.4e-27 94.6 2.1 2.2 2 0 0 2 2 2 2 Ribosome biogenesis protein SLX9 Peptidase_C48 PF02902.14 KND89948.1 - 1.1e-17 64.3 0.0 3.8e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pam17 PF08566.5 KND89949.1 - 2.3e-64 216.2 0.0 2.9e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ThiF PF00899.16 KND89950.1 - 4.4e-40 136.6 0.0 8.3e-40 135.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KND89950.1 - 1.2e-22 79.2 0.0 3.2e-22 77.8 0.0 1.8 2 0 0 2 2 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KND89950.1 - 5e-13 49.3 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KND89950.1 - 0.0022 18.1 0.2 0.013 15.6 0.1 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KND89950.1 - 0.0055 16.9 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KND89950.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CTNNB1_binding PF08347.6 KND89950.1 - 0.023 14.9 0.0 0.061 13.5 0.0 1.7 2 0 0 2 2 2 0 N-terminal CTNNB1 binding 3HCDH_N PF02737.13 KND89950.1 - 0.059 13.0 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KND89950.1 - 0.061 12.7 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KND89950.1 - 0.094 13.1 1.1 0.19 12.1 0.8 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND89950.1 - 0.14 11.1 1.3 0.24 10.4 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KND89950.1 - 0.15 11.1 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TMF_DNA_bd PF12329.3 KND89950.1 - 0.16 11.7 1.5 0.28 11.0 1.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Alginate_lyase2 PF08787.6 KND89951.1 - 6.8e-11 42.2 0.0 1.5e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 Alginate lyase HNH_2 PF13391.1 KND89952.1 - 1.9e-06 27.5 0.1 5.1e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 HNH endonuclease TRAM_LAG1_CLN8 PF03798.11 KND89953.1 - 4.2e-42 143.9 18.9 4.2e-42 143.9 13.1 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KND89953.1 - 4.7e-13 48.4 0.0 1.1e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein zf-DHHC PF01529.15 KND89953.1 - 9.3 5.6 6.8 35 3.7 2.8 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase GFA PF04828.9 KND89954.1 - 2.4e-10 40.2 1.4 2.4e-10 40.2 1.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KND89954.1 - 0.048 13.9 4.5 21 5.5 3.1 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar Caps_synth PF05704.7 KND89955.1 - 1.1e-06 28.0 0.0 2.4e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KND89955.1 - 0.0038 17.5 0.0 0.0066 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif C2 PF00168.25 KND89956.1 - 9e-10 38.2 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain PAD PF03068.10 KND89957.1 - 1.4e-51 175.1 0.0 7.1e-35 120.1 0.0 2.1 2 0 0 2 2 2 2 Protein-arginine deiminase (PAD) CoA_transf_3 PF02515.12 KND89958.1 - 3.2e-65 218.9 0.3 4.1e-65 218.6 0.2 1.1 1 0 0 1 1 1 1 CoA-transferase family III NACHT PF05729.7 KND89959.1 - 8.8e-14 51.5 0.0 2.2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain HEAT_2 PF13646.1 KND89959.1 - 7.4e-08 32.5 3.3 1.2e-06 28.6 0.0 3.4 3 1 2 5 5 4 1 HEAT repeats AAA_17 PF13207.1 KND89959.1 - 0.0003 21.5 0.3 0.007 17.1 0.2 3.3 4 1 0 4 4 3 1 AAA domain HEAT_EZ PF13513.1 KND89959.1 - 0.00035 20.9 0.6 0.0024 18.3 0.1 2.8 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.17 KND89959.1 - 0.00061 19.6 0.0 0.31 11.2 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat NB-ARC PF00931.17 KND89959.1 - 0.0011 17.9 0.2 0.0041 16.0 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 KND89959.1 - 0.0016 18.5 0.1 0.006 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KND89959.1 - 0.0043 15.7 0.1 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.1 KND89959.1 - 0.011 16.0 0.1 0.058 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KND89959.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND89959.1 - 0.062 13.2 4.7 1.6 8.7 0.0 3.5 2 2 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 KND89959.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sugar_tr PF00083.19 KND89960.1 - 1.1e-111 373.6 21.1 3.2e-111 372.1 14.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND89960.1 - 3.4e-17 62.1 42.0 1.8e-10 40.0 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_60s PF00428.14 KND89961.1 - 1.9 8.9 13.8 0.079 13.3 3.4 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1918 PF08940.6 KND89962.1 - 0.011 15.0 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4013 PF13197.1 KND89962.1 - 1.8 7.8 7.0 0.08 12.2 0.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Lipase_3 PF01764.20 KND89963.1 - 3e-15 56.0 0.0 4.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KND89963.1 - 0.0083 15.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND89963.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 KND89963.1 - 0.16 10.8 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1399 PF07173.7 KND89965.1 - 4.7e-21 75.4 0.0 3.2e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) ABC_tran PF00005.22 KND89966.1 - 4.5e-33 114.4 0.0 1e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KND89966.1 - 3.2e-06 26.7 0.1 4.6e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KND89966.1 - 1.2e-05 24.7 0.1 0.0029 16.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KND89966.1 - 3.6e-05 23.7 0.0 7.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_16 PF13191.1 KND89966.1 - 0.0044 17.0 0.9 0.014 15.3 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 KND89966.1 - 0.0045 16.9 0.0 0.55 10.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KND89966.1 - 0.0057 15.5 0.0 0.0097 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KND89966.1 - 0.013 15.6 0.3 0.081 13.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KND89966.1 - 0.031 13.7 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KND89966.1 - 0.045 12.8 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KND89966.1 - 0.07 13.9 0.1 0.17 12.6 0.0 1.8 2 1 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 KND89966.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 KND89966.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.11 KND89967.1 - 4.4e-40 137.4 34.0 4.4e-40 137.4 23.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND89967.1 - 9.9e-20 70.5 24.7 1.8e-19 69.7 17.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KND89967.1 - 2.6e-06 25.9 7.2 5.5e-06 24.8 5.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAP2 PF01569.16 KND89967.1 - 0.0024 17.5 4.1 0.0024 17.5 2.8 3.1 3 1 0 3 3 3 1 PAP2 superfamily DUF4112 PF13430.1 KND89967.1 - 0.79 9.6 4.5 1.5 8.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4112) Kdo PF06293.9 KND89968.1 - 0.16 11.0 0.0 0.31 10.0 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease_2 PF13520.1 KND89970.1 - 3.2e-50 170.9 50.1 3.9e-50 170.6 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND89970.1 - 2.1e-25 89.0 46.7 2.7e-25 88.6 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 KND89970.1 - 2.7 7.8 0.0 2.7 7.8 0.0 3.5 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 Iso_dh PF00180.15 KND89971.1 - 1.7e-78 264.0 0.0 2.4e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 KND89971.1 - 1.6e-67 227.3 0.0 2.4e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89971.1 - 1.5e-49 168.3 0.0 2.9e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND89971.1 - 0.006 15.5 0.0 0.02 13.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like AAA_3 PF07726.6 KND89971.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ecm29 PF13001.2 KND89972.1 - 5.3e-107 358.3 0.1 6.5e-105 351.4 0.1 2.3 2 0 0 2 2 2 2 Proteasome stabiliser UBA_4 PF14555.1 KND89972.1 - 6.7e-13 47.9 0.0 1.1e-11 44.0 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain Thioredoxin_7 PF13899.1 KND89972.1 - 1.5e-12 47.3 0.1 3.7e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 KND89972.1 - 5.5e-08 32.7 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain HEAT_EZ PF13513.1 KND89972.1 - 0.0044 17.4 14.4 0.85 10.2 0.0 7.8 6 1 2 8 8 8 2 HEAT-like repeat Thioredox_DsbH PF03190.10 KND89972.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KND89972.1 - 0.25 11.5 0.0 0.99 9.6 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like domain HEAT PF02985.17 KND89972.1 - 0.45 10.7 14.1 75 3.8 0.0 8.0 10 0 0 10 10 10 0 HEAT repeat DAO PF01266.19 KND89974.1 - 1.1e-15 57.4 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NatB_MDM20 PF09797.4 KND89975.1 - 3.5e-42 144.4 0.0 4.9e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_M35 PF02102.10 KND89976.1 - 6.3e-70 235.6 12.9 8.2e-70 235.2 8.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KND89976.1 - 2.3e-11 44.3 4.2 2.3e-11 44.3 2.9 1.9 2 1 1 3 3 3 1 Lysine-specific metallo-endopeptidase Acetyltransf_1 PF00583.19 KND89977.1 - 1.4e-09 37.8 0.0 2.6e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND89977.1 - 1.2e-05 25.3 0.0 3.7e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND89977.1 - 0.00037 20.5 0.0 0.0076 16.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND89977.1 - 0.00074 19.3 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND89977.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein DUF3445 PF11927.3 KND89978.1 - 3.6e-67 226.3 0.0 5.5e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SWIB PF02201.13 KND89978.1 - 3.1e-25 87.6 0.2 5.4e-25 86.8 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribonuc_2-5A PF06479.7 KND89979.1 - 1.5e-43 147.6 0.0 3e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KND89979.1 - 4e-42 144.1 0.0 5.8e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND89979.1 - 3e-21 75.6 0.0 1.2e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KND89979.1 - 2.7e-07 30.3 2.2 0.00015 21.2 0.1 2.8 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 KND89979.1 - 2.5e-05 23.5 0.5 0.014 14.9 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 KND89979.1 - 0.0017 17.4 0.0 0.0046 16.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KND89979.1 - 0.038 13.3 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KND89979.1 - 0.049 13.3 0.1 0.049 13.3 0.1 3.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family eIF2A PF08662.6 KND89980.1 - 3e-41 141.2 3.0 5e-39 134.0 0.1 4.1 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 KND89980.1 - 3.6e-05 23.5 0.0 7.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KND89980.1 - 0.00079 19.2 0.1 1.8 8.5 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_6 PF14259.1 KND89980.1 - 0.0013 18.6 0.0 0.0039 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.7 KND89980.1 - 0.0017 16.2 0.0 0.0041 15.0 0.0 1.5 1 0 0 1 1 1 1 IKI3 family RRM_1 PF00076.17 KND89980.1 - 0.0036 16.9 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2 PF00152.15 KND89981.1 - 8.9e-88 294.2 0.2 1.4e-87 293.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND89981.1 - 2.6e-10 40.0 0.0 5.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KND89981.1 - 2.1e-08 33.6 0.4 7.1e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3069 PF11269.3 KND89981.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3069) WBS_methylT PF12589.3 KND89982.1 - 1e-16 61.1 2.4 1.6e-16 60.5 1.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KND89982.1 - 2.5e-11 43.8 0.0 6.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND89982.1 - 4.8e-07 30.0 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND89982.1 - 7.6e-06 25.5 0.0 1.3e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND89982.1 - 7.5e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KND89982.1 - 0.00012 22.5 0.0 0.00032 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND89982.1 - 0.00013 22.0 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND89982.1 - 0.00014 22.4 0.0 0.00038 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND89982.1 - 0.00022 20.9 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND89982.1 - 0.015 14.3 0.0 0.27 10.2 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KND89982.1 - 0.065 12.3 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Erv26 PF04148.8 KND89983.1 - 2.1e-83 278.8 2.7 2.7e-83 278.4 1.9 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 QueT PF06177.6 KND89983.1 - 0.02 14.8 1.6 0.02 14.8 1.1 1.8 2 0 0 2 2 2 0 QueT transporter DUF3377 PF11857.3 KND89983.1 - 0.022 14.3 0.1 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cytochrom_C_asm PF01578.15 KND89983.1 - 0.25 10.8 7.0 0.11 11.9 1.5 2.1 2 0 0 2 2 2 0 Cytochrome C assembly protein Claudin_2 PF13903.1 KND89983.1 - 1.1 8.8 9.6 0.1 12.2 1.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Period_C PF12114.3 KND89984.1 - 0.086 12.4 0.6 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Fungal_trans_2 PF11951.3 KND89985.1 - 3e-20 72.1 0.0 4e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND89985.1 - 0.009 15.9 11.7 0.018 14.9 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 KND89986.1 - 1.4e-47 161.6 1.1 1.4e-47 161.6 0.8 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND89986.1 - 7.8e-42 142.8 8.4 7.8e-42 142.8 5.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND89986.1 - 6e-31 108.5 0.0 2.5e-30 106.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND89986.1 - 4.7e-19 68.1 0.0 1.6e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KND89986.1 - 2.2e-13 50.7 2.8 7.9e-13 48.9 1.9 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND89986.1 - 4.5e-12 45.2 0.0 1.3e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KND89986.1 - 0.00057 19.5 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nucleos_tra2_N PF01773.15 KND89986.1 - 2.3 8.5 9.0 9.5 6.6 0.0 3.6 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus DUF2207 PF09972.4 KND89986.1 - 9.8 4.6 11.3 1.8 7.0 0.0 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 KND89987.1 - 2.3e-25 89.5 18.2 3.4e-25 88.9 12.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KND89987.1 - 3.7e-07 30.2 0.0 7.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DDE_3 PF13358.1 KND89988.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-ribbon_3 PF13248.1 KND89988.1 - 0.11 11.7 0.1 0.11 11.7 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain RabGAP-TBC PF00566.13 KND89989.1 - 2.2e-30 105.7 0.0 3.3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cpn60_TCP1 PF00118.19 KND89990.1 - 5.1e-126 421.1 10.1 6.2e-126 420.8 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAPPC10 PF12584.3 KND89991.1 - 5.7e-22 77.8 0.0 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KND89991.1 - 0.002 17.6 0.1 0.0033 16.9 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_12 PF13424.1 KND89991.1 - 0.044 13.7 0.2 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat NPIP PF06409.6 KND89992.1 - 0.95 8.1 3.5 1.4 7.6 2.4 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) ADH_N PF08240.7 KND89993.1 - 0.00091 18.9 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 KND89994.1 - 8.5e-12 44.7 0.1 2.8e-06 26.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain HsbA PF12296.3 KND89995.1 - 2.7e-25 88.6 3.6 3.8e-25 88.1 2.5 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A GSCFA PF08885.6 KND89995.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 GSCFA family Glyco_transf_20 PF00982.16 KND89997.1 - 5.5e-163 542.8 0.0 7.7e-163 542.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KND89997.1 - 1.6e-40 138.4 0.0 3.5e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase Aminotran_4 PF01063.14 KND89998.1 - 8.5e-21 74.4 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV MutS_V PF00488.16 KND89999.1 - 3.4e-72 242.6 0.0 5.6e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND89999.1 - 6.7e-35 120.7 3.1 3.4e-34 118.4 2.1 2.0 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KND89999.1 - 2.9e-09 36.9 0.0 8e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KND89999.1 - 8.5e-06 25.8 1.1 4.6e-05 23.5 0.0 2.7 3 1 0 3 3 3 1 MutS domain II Sec34 PF04136.10 KND89999.1 - 0.11 12.1 3.4 0.21 11.2 0.2 2.5 2 1 1 3 3 3 0 Sec34-like family WD40 PF00400.27 KND90000.1 - 5.3e-79 257.5 23.2 1.2e-14 53.5 0.3 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat FAR1 PF03101.10 KND90000.1 - 4.4e-07 30.3 0.6 1.4e-06 28.7 0.4 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain Nup160 PF11715.3 KND90000.1 - 1.7e-05 23.2 6.9 0.063 11.4 0.1 4.4 2 2 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KND90000.1 - 3.8e-05 23.4 2.0 0.0014 18.3 0.1 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KND90000.1 - 0.00024 20.6 0.2 0.00024 20.6 0.1 2.4 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain FAD_binding_9 PF08021.6 KND90000.1 - 0.015 15.2 0.1 0.43 10.5 0.0 2.8 2 1 1 3 3 3 0 Siderophore-interacting FAD-binding domain Peptidase_M20 PF01546.23 KND90001.1 - 6.6e-21 74.6 3.9 1.1e-20 73.8 2.7 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND90001.1 - 1.1e-18 66.9 0.0 2.8e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KND90001.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 AP_endonuc_2 PF01261.19 KND90002.1 - 2.4e-29 102.1 0.0 3.2e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DCR PF14047.1 KND90002.1 - 0.082 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region NmrA PF05368.8 KND90003.1 - 7.8e-22 77.6 0.1 1.6e-21 76.6 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND90003.1 - 6.1e-11 42.6 0.6 6.1e-11 42.6 0.4 1.7 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KND90003.1 - 0.0022 17.0 0.1 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF3394 PF11874.3 KND90003.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) adh_short PF00106.20 KND90003.1 - 0.041 13.8 0.4 0.069 13.0 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KND90003.1 - 0.087 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 KR domain IF-2B PF01008.12 KND90004.1 - 1.2e-76 257.3 0.1 1.4e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family RhoGEF PF00621.15 KND90005.1 - 9.5e-28 97.2 0.0 1.8e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Exo5 PF09810.4 KND90006.1 - 3.2e-107 358.4 0.0 3.9e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease ThiF PF00899.16 KND90007.1 - 1.2e-54 183.8 0.1 6.4e-32 110.2 0.0 2.7 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 KND90007.1 - 1.3e-38 131.9 0.0 2.9e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KND90007.1 - 2e-38 129.7 2.5 1.2e-27 95.1 0.1 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KND90007.1 - 4.4e-25 86.7 4.1 6.1e-20 70.3 0.6 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Omega-toxin PF06357.6 KND90009.1 - 0.024 14.2 0.3 0.046 13.2 0.2 1.4 1 0 0 1 1 1 0 Omega-atracotoxin GST_N_2 PF13409.1 KND90011.1 - 1.9e-20 72.6 0.0 5e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KND90011.1 - 5.1e-15 55.1 0.0 9.3e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KND90011.1 - 1.1e-05 25.5 0.1 0.0008 19.5 0.1 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KND90011.1 - 4.6e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND90011.1 - 0.00025 21.4 0.0 0.00057 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sec1 PF00995.18 KND90013.1 - 8.3e-134 447.2 0.0 9.9e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 KND90013.1 - 0.0047 16.2 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein CIII (Apo-CIII) G-patch PF01585.18 KND90014.1 - 5.9e-07 29.1 0.4 1.4e-06 27.9 0.3 1.7 1 0 0 1 1 1 1 G-patch domain NAD_binding_10 PF13460.1 KND90015.1 - 5.4e-17 62.3 0.1 1e-16 61.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND90015.1 - 4.1e-05 23.1 0.0 7.3e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND90015.1 - 0.026 13.4 0.0 0.16 10.8 0.0 2.1 2 1 1 3 3 3 0 Male sterility protein adh_short PF00106.20 KND90015.1 - 0.027 14.3 0.1 0.062 13.2 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase HTH_Tnp_Tc5 PF03221.11 KND90017.1 - 8.9e-18 63.8 1.2 5.2e-17 61.4 0.1 2.7 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain MitMem_reg PF13012.1 KND90017.1 - 0.02 14.9 0.2 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function EAP30 PF04157.11 KND90018.1 - 3.5e-55 186.5 0.0 4.5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KND90018.1 - 1e-25 89.3 0.0 1.7e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KND90018.1 - 0.0042 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 KND90018.1 - 0.7 9.4 9.1 0.1 12.1 0.4 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 KND90018.1 - 2 7.6 19.4 0.97 8.5 5.0 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others SAC3_GANP PF03399.11 KND90019.1 - 3e-64 216.3 0.1 4.2e-64 215.8 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WD40 PF00400.27 KND90020.1 - 6.6e-59 193.8 39.3 7.2e-13 47.8 0.1 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat NACHT PF05729.7 KND90020.1 - 1.8e-15 56.9 0.1 5.7e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KND90020.1 - 2.9e-07 29.1 0.7 0.0066 14.7 0.2 3.7 3 1 1 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 KND90020.1 - 8.6e-05 20.8 18.4 0.27 9.3 0.7 6.6 3 2 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KND90020.1 - 0.004 15.9 0.1 0.3 9.7 0.0 2.6 3 0 0 3 3 3 1 Nup133 N terminal like PD40 PF07676.7 KND90020.1 - 0.04 13.6 0.7 27 4.5 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat AAA_19 PF13245.1 KND90020.1 - 0.041 13.6 0.0 0.19 11.5 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KND90020.1 - 0.051 13.7 0.0 0.86 9.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase CDtoxinA PF03498.9 KND90020.1 - 0.082 12.2 0.1 8.6 5.7 0.0 3.2 2 1 0 3 3 3 0 Cytolethal distending toxin A/C family SH3_1 PF00018.23 KND90021.1 - 1.3e-13 50.0 0.0 1.2e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.19 KND90021.1 - 2e-13 50.1 0.1 2e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.1 KND90021.1 - 6.6e-06 25.6 0.9 0.00085 18.8 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KND90021.1 - 1e-05 24.9 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.19 KND90021.1 - 1.8e-05 24.3 0.1 3.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Peptidase_S9 PF00326.16 KND90023.1 - 1e-41 142.5 0.0 1.6e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND90023.1 - 3.6e-08 33.2 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND90023.1 - 4.3e-06 26.7 1.5 1.9e-05 24.6 1.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 KND90023.1 - 0.0028 16.7 0.0 0.073 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 KND90023.1 - 0.032 13.7 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 KND90023.1 - 0.089 11.2 0.0 1.2 7.5 0.0 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Serglycin PF04360.7 KND90024.1 - 0.0046 16.6 0.9 0.0071 16.0 0.6 1.3 1 0 0 1 1 1 1 Serglycin F-box-like PF12937.2 KND90026.1 - 5.9e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND90026.1 - 0.0019 17.8 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain 7tm_2 PF00002.19 KND90027.1 - 3.4e-13 49.2 2.0 5.4e-13 48.5 1.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KND90027.1 - 0.017 14.0 9.6 0.52 9.1 1.2 2.4 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor Git3 PF11710.3 KND90027.1 - 0.025 14.1 9.7 0.059 12.9 6.7 1.6 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 4HBT PF03061.17 KND90028.1 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily NAD_Gly3P_dh_N PF01210.18 KND90029.1 - 1e-44 151.9 0.0 1.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KND90029.1 - 5.3e-41 139.7 0.4 8.9e-41 139.0 0.2 1.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KND90029.1 - 0.095 13.1 0.0 25 5.4 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AIG2_2 PF13772.1 KND90030.1 - 2.5e-06 27.5 0.1 0.00096 19.2 0.0 2.4 2 0 0 2 2 2 2 AIG2-like family Abhydrolase_5 PF12695.2 KND90033.1 - 3.1e-07 30.2 0.0 4.6e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KND90033.1 - 4.4e-05 22.8 0.0 0.00016 21.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KND90033.1 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KND90034.1 - 8.4e-24 84.7 0.0 9.3e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND90034.1 - 9.4e-24 84.2 0.0 1e-23 84.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND90034.1 - 1.4e-14 54.0 0.1 5e-13 49.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KND90034.1 - 7.6e-05 22.2 0.0 0.0002 20.9 0.0 1.7 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KND90034.1 - 0.00014 21.1 0.0 0.004 16.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KND90034.1 - 0.00041 19.7 0.0 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF915 PF06028.6 KND90034.1 - 0.00046 19.3 0.0 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.8 KND90034.1 - 0.012 15.0 0.2 0.037 13.4 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) NAD_binding_10 PF13460.1 KND90035.1 - 1.6e-09 38.0 0.4 2.4e-09 37.4 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KND90035.1 - 3.3e-08 33.0 0.0 6.8e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KND90035.1 - 0.011 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_5 PF07994.7 KND90035.1 - 0.053 12.9 0.2 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DapB_N PF01113.15 KND90035.1 - 0.12 12.2 0.1 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Toxin_39 PF15500.1 KND90035.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin Semialdhyde_dh PF01118.19 KND90035.1 - 0.15 12.3 0.1 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 KND90036.1 - 5.5e-50 170.0 43.5 5.5e-50 170.0 30.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND90036.1 - 9.4e-11 40.6 14.6 1.1e-10 40.3 10.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3188 PF11384.3 KND90036.1 - 0.095 12.2 5.0 0.074 12.6 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Chromo PF00385.19 KND90037.1 - 3e-06 26.8 0.7 3e-06 26.8 0.5 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PIN_3 PF13470.1 KND90037.1 - 0.088 13.4 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 PIN domain RRM_1 PF00076.17 KND90038.1 - 0.00089 18.8 0.0 0.0027 17.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND90038.1 - 0.098 12.5 0.0 8 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 KND90039.1 - 1.6e-30 106.1 0.0 3e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KND90039.1 - 1.1e-17 64.3 4.2 2.9e-17 62.9 2.9 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 KND90039.1 - 2.3e-05 24.4 0.1 5.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 KND90039.1 - 0.00022 20.5 0.0 0.0014 17.9 0.0 1.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 KND90039.1 - 0.0066 16.0 0.4 0.035 13.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KND90039.1 - 0.013 15.4 0.0 0.51 10.2 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KND90039.1 - 0.028 14.5 0.3 0.17 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 KND90039.1 - 0.033 14.0 0.2 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KND90039.1 - 0.035 13.1 0.0 0.089 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 KND90039.1 - 0.081 12.4 0.2 0.27 10.7 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 KND90039.1 - 0.29 11.0 1.6 1.5 8.7 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Peptidase_M20 PF01546.23 KND90040.1 - 2.4e-23 82.6 0.0 3.2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND90040.1 - 3.7e-11 42.7 0.0 6.5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Acetyltransf_1 PF00583.19 KND90041.1 - 2.8e-13 49.7 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND90041.1 - 3.7e-07 30.2 0.0 5.3e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND90041.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND90041.1 - 0.002 18.0 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND90041.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KND90041.1 - 0.083 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GYF PF02213.11 KND90042.1 - 0.062 12.8 0.5 0.73 9.4 0.1 2.2 1 1 1 2 2 2 0 GYF domain HPP PF04982.8 KND90043.1 - 4e-37 126.6 5.1 4e-37 126.6 3.5 1.4 2 0 0 2 2 2 1 HPP family DUF2828 PF11443.3 KND90044.1 - 5.5e-170 566.0 0.0 7.8e-170 565.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Prefoldin PF02996.12 KND90044.1 - 0.08 12.5 3.0 2.8 7.6 0.1 3.4 3 1 1 4 4 4 0 Prefoldin subunit DUF1212 PF06738.7 KND90045.1 - 1.5e-56 190.9 1.4 4.6e-52 176.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KND90045.1 - 2.4e-20 72.8 26.3 5.1e-14 52.3 0.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) DUF2301 PF10063.4 KND90045.1 - 4.1 7.6 7.9 1.7 8.8 2.7 2.1 1 1 1 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Asp PF00026.18 KND90046.1 - 2.2e-76 257.1 10.6 2.6e-76 256.8 7.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND90046.1 - 1.6e-08 34.6 0.9 7e-07 29.3 0.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND90046.1 - 0.00012 22.4 2.6 0.14 12.6 0.3 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KND90046.1 - 0.00059 19.4 0.0 0.0081 15.7 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal PBP PF01161.15 KND90047.1 - 7.1e-07 29.1 0.1 7.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GFO_IDH_MocA PF01408.17 KND90048.1 - 0.0022 18.4 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold G6PD_N PF00479.17 KND90048.1 - 0.036 14.3 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.12 KND90049.1 - 0.00017 20.7 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND90049.1 - 0.00065 18.9 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KND90049.1 - 0.00075 19.2 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND90049.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KND90049.1 - 0.18 10.6 0.0 0.39 9.5 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Peptidase_C48 PF02902.14 KND90050.1 - 0.024 14.2 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain APH PF01636.18 KND90051.1 - 6.7e-07 29.2 1.6 6.1e-06 26.1 1.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND90051.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fungal_trans_2 PF11951.3 KND90052.1 - 9.6e-16 57.3 5.2 1.6e-15 56.6 3.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KND90052.1 - 5.2e-09 35.2 21.5 0.00092 18.0 1.8 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Zn_clus PF00172.13 KND90052.1 - 1.2e-06 28.3 10.1 2.5e-06 27.3 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNO PF01174.14 KND90053.1 - 2.2e-54 183.9 0.0 9.2e-53 178.6 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KND90053.1 - 8.1e-08 32.0 0.1 1.6e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 KND90053.1 - 0.00026 20.4 0.1 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KND90053.1 - 0.001 18.3 0.7 0.0016 17.7 0.5 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 KND90053.1 - 0.004 16.6 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 KND90053.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 SOR_SNZ PF01680.12 KND90054.1 - 3.5e-104 346.9 6.8 5.5e-104 346.2 4.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KND90054.1 - 2e-09 36.8 4.2 2.3e-07 30.1 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KND90054.1 - 0.00087 18.6 0.2 0.059 12.6 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 KND90054.1 - 0.00093 18.3 0.9 0.0025 16.9 0.0 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 KND90054.1 - 0.0018 17.2 0.2 0.56 8.9 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 KND90054.1 - 0.014 14.3 1.6 0.14 11.1 0.0 2.7 2 2 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 KND90054.1 - 0.018 14.4 0.5 0.024 14.0 0.3 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF4398 PF14346.1 KND90054.1 - 0.027 14.5 0.3 0.027 14.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TMP-TENI PF02581.12 KND90054.1 - 0.083 11.9 1.6 0.88 8.6 0.0 2.6 2 2 0 2 2 2 0 Thiamine monophosphate synthase/TENI AAT PF03417.11 KND90055.1 - 2.3e-19 69.7 0.0 1.2e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KND90055.1 - 3.2e-05 24.2 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans_2 PF11951.3 KND90056.1 - 1.6e-09 36.8 0.4 2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90056.1 - 0.00077 19.3 10.9 0.0018 18.1 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.8 KND90057.1 - 5.9e-15 55.3 0.0 8.5e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase RRM_1 PF00076.17 KND90058.1 - 2e-46 155.4 0.0 1.6e-16 59.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND90058.1 - 1.4e-25 89.0 0.0 6.2e-10 38.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND90058.1 - 1.3e-21 76.1 0.0 1.3e-08 34.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND90058.1 - 4.8e-07 29.4 0.0 0.0034 17.1 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KND90058.1 - 1.7e-05 24.6 0.0 0.00015 21.5 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Pyr_redox_3 PF13738.1 KND90060.1 - 8.4e-23 81.4 0.0 2.9e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KND90060.1 - 1.5e-06 26.7 0.0 1.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND90060.1 - 1.9e-05 24.6 0.2 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND90060.1 - 0.00035 20.3 0.0 0.027 14.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KND90060.1 - 0.0026 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KND90060.1 - 0.0038 17.3 0.0 0.046 13.8 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KND90060.1 - 0.0062 16.4 0.0 1.2 8.9 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND90060.1 - 0.038 14.3 0.2 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PI-PLC-X PF00388.14 KND90061.1 - 2.3e-43 147.1 0.0 3.4e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KND90061.1 - 4.7e-32 110.4 0.0 9.5e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Phytase PF02333.10 KND90062.1 - 0.00025 19.9 0.0 0.2 10.2 0.0 3.0 3 0 0 3 3 3 3 Phytase Glyco_hydro_20 PF00728.17 KND90064.1 - 4e-95 318.9 0.2 5.1e-95 318.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KND90064.1 - 7.8e-22 78.2 0.0 1.4e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KND90064.1 - 7.9e-06 26.4 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ABC_tran PF00005.22 KND90065.1 - 4.3e-45 153.3 0.0 5.1e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND90065.1 - 2.2e-34 119.1 31.2 4.8e-27 95.0 8.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KND90065.1 - 1.3e-12 48.2 0.1 0.0012 18.8 0.0 4.3 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 KND90065.1 - 7.5e-09 35.1 0.9 0.085 12.0 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KND90065.1 - 1.7e-06 28.1 1.3 0.004 17.1 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KND90065.1 - 3.8e-06 26.3 1.4 0.053 13.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KND90065.1 - 1.8e-05 24.6 1.5 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 KND90065.1 - 6.6e-05 22.1 1.9 0.063 12.4 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KND90065.1 - 0.00012 22.0 0.1 0.47 10.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KND90065.1 - 0.00014 22.3 0.6 0.055 13.9 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KND90065.1 - 0.00016 21.2 0.9 0.066 12.6 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 KND90065.1 - 0.00029 20.9 0.0 0.51 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND90065.1 - 0.00038 19.9 0.6 0.27 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KND90065.1 - 0.00041 19.3 1.5 0.53 9.1 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 KND90065.1 - 0.00087 19.1 0.3 0.29 11.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KND90065.1 - 0.0016 17.9 1.0 1 8.8 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 KND90065.1 - 0.0022 17.6 2.4 0.21 11.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 KND90065.1 - 0.0044 16.4 0.2 0.73 9.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 KND90065.1 - 0.0053 15.4 1.2 0.3 9.6 0.1 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KND90065.1 - 0.0092 15.8 0.0 4.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KND90065.1 - 0.011 15.5 3.7 0.022 14.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KND90065.1 - 0.015 15.6 0.8 4.4 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KND90065.1 - 0.025 15.4 2.6 2.8 8.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KND90065.1 - 0.051 13.2 0.1 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase ArgK PF03308.11 KND90065.1 - 0.11 11.2 2.5 0.44 9.2 0.2 2.2 2 0 0 2 2 2 0 ArgK protein NB-ARC PF00931.17 KND90065.1 - 0.14 11.0 0.0 3.6 6.3 0.0 2.5 2 1 1 3 3 3 0 NB-ARC domain AAA_14 PF13173.1 KND90065.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KND90065.1 - 0.17 12.1 1.1 13 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KND90065.1 - 0.19 11.1 2.3 3.8 6.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KND90065.1 - 0.27 10.7 1.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KND90065.1 - 0.31 10.0 0.6 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.7 KND90065.1 - 0.37 9.8 1.8 2.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.10 KND90065.1 - 0.58 8.7 0.5 7.5 5.0 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.7 KND90066.1 - 1.9e-09 37.3 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND90066.1 - 7.7e-05 22.7 0.4 0.00043 20.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KND90066.1 - 0.00078 18.3 0.0 0.0015 17.4 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 KND90066.1 - 0.026 13.5 0.1 0.06 12.3 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.15 KND90066.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KND90066.1 - 0.048 13.9 0.1 0.2 11.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KND90066.1 - 0.065 13.4 0.0 0.23 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND90066.1 - 0.087 13.6 0.5 0.88 10.4 0.4 2.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KND90066.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND90066.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KND90068.1 - 2.6e-06 27.0 2.9 0.038 13.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 KND90068.1 - 0.00092 17.4 0.0 0.0016 16.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 KND90069.1 - 1.9e-11 43.3 6.8 4.1e-05 23.2 0.2 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 KND90069.1 - 0.019 13.1 0.0 0.024 12.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Pkinase PF00069.20 KND90070.1 - 4.9e-11 42.2 0.0 8.3e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KND90070.1 - 0.0013 18.5 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KND90070.1 - 0.0055 15.8 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.18 KND90071.1 - 1.9e-28 99.3 0.0 5.1e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND90071.1 - 6.3e-09 35.0 0.0 1.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KND90071.1 - 8.6e-06 25.6 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND90071.1 - 0.0088 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KND90071.1 - 0.026 14.8 0.0 0.088 13.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF2077 PF09850.4 KND90071.1 - 0.15 11.4 3.7 0.38 10.1 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) AAA_21 PF13304.1 KND90071.1 - 0.29 11.0 0.0 0.55 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cyanate_lyase PF02560.9 KND90072.1 - 1.6e-27 94.8 0.0 2.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Crystall PF00030.14 KND90072.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Beta/Gamma crystallin HTH_31 PF13560.1 KND90072.1 - 0.0048 17.0 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 KND90072.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Pkinase PF00069.20 KND90073.1 - 3.1e-25 88.8 0.0 2.7e-13 49.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND90073.1 - 0.00027 20.0 0.0 0.063 12.3 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KND90073.1 - 0.22 10.4 0.0 19 4.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Hydrophobin PF01185.13 KND90076.1 - 0.028 14.8 6.8 0.27 11.6 0.2 2.2 1 1 1 2 2 2 0 Fungal hydrophobin Hormone_5 PF00184.12 KND90076.1 - 0.38 11.3 10.7 3.4 8.2 0.6 2.2 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Zn_clus PF00172.13 KND90077.1 - 4.7e-07 29.6 7.6 8.9e-07 28.7 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 KND90078.1 - 2.7e-10 41.2 0.0 5e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND90078.1 - 5.5e-07 29.3 0.0 1.5e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND90078.1 - 2.6e-06 26.9 0.0 4.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KND90078.1 - 0.12 11.4 0.4 3.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFA PF04828.9 KND90079.1 - 2.1e-21 75.6 0.6 2.9e-21 75.2 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aminotran_1_2 PF00155.16 KND90080.1 - 8e-43 146.7 0.0 9.6e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 KND90080.1 - 0.086 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Pribosyltran PF00156.22 KND90081.1 - 5.7e-15 55.1 0.7 8.1e-15 54.6 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KND90081.1 - 0.064 12.4 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Zn_clus PF00172.13 KND90083.1 - 1.1e-06 28.4 7.3 2e-06 27.5 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND90083.1 - 0.00014 20.8 0.1 0.00022 20.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 KND90086.1 - 4.7e-59 199.6 0.0 8.3e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90086.1 - 9.4e-35 119.9 0.0 1.5e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND90086.1 - 7.3e-11 41.5 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND90086.1 - 0.036 13.1 1.1 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND90086.1 - 0.17 11.5 5.6 0.16 11.6 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family NDUF_B8 PF05821.6 KND90087.1 - 3.8e-06 26.6 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 KND90088.1 - 1.7e-75 253.5 0.3 2.8e-75 252.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND90088.1 - 1.2e-14 53.8 0.0 4.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND90088.1 - 1.2e-08 35.0 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND90088.1 - 4.4e-05 23.0 0.0 8.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KND90088.1 - 0.00012 21.0 0.1 0.17 10.6 0.0 2.4 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.8 KND90088.1 - 0.002 17.8 7.9 0.002 17.8 5.5 2.2 2 0 0 2 2 2 1 HSA DEAD_2 PF06733.10 KND90088.1 - 0.19 11.0 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Ilm1 PF10311.4 KND90089.1 - 1.9e-55 186.8 0.2 2.2e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 KND90090.1 - 4.7e-36 122.0 8.5 2.6e-07 30.0 0.1 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KND90090.1 - 2.9e-19 69.5 0.1 8.4e-14 51.9 0.0 4.2 2 2 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KND90090.1 - 1.4e-06 28.3 0.3 0.00024 21.0 0.0 3.5 2 1 1 3 3 3 2 Prenyltransferase-like DUF1903 PF08991.5 KND90090.1 - 0.003 17.6 3.4 0.0065 16.5 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KND90090.1 - 0.007 16.2 4.9 0.015 15.2 3.4 1.6 1 0 0 1 1 1 1 CHCH domain Sulfotransfer_3 PF13469.1 KND90091.1 - 6.4e-07 30.4 0.8 9.9e-07 29.8 0.5 1.4 1 1 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.11 KND90093.1 - 2.2e-10 39.7 56.7 1e-09 37.6 21.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HemY_N PF07219.8 KND90093.1 - 0.79 9.3 4.9 0.21 11.1 0.7 2.2 2 0 0 2 2 2 0 HemY protein N-terminus Aa_trans PF01490.13 KND90094.1 - 1.4e-43 148.9 29.7 1.6e-43 148.7 20.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MOSC_N PF03476.11 KND90095.1 - 2e-21 75.9 0.0 4.7e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KND90095.1 - 4.5e-19 68.2 0.0 8.8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 KND90095.1 - 1.9e-17 63.0 0.0 3.6e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_18 PF00704.23 KND90096.1 - 2.7e-83 280.2 6.1 3.7e-83 279.8 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HAD PF12710.2 KND90097.1 - 1.4e-12 48.1 0.0 1.9e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND90097.1 - 0.00023 21.6 0.0 0.00054 20.4 0.0 1.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KND90097.1 - 0.0035 16.5 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase TFIIF_beta PF02270.10 KND90098.1 - 2.4e-60 204.7 0.1 2.9e-60 204.3 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Glyco_hydro_15 PF00723.16 KND90099.1 - 1.3e-51 175.5 0.0 5.1e-50 170.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 RRM_1 PF00076.17 KND90101.1 - 2.1e-16 59.2 0.0 3.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND90101.1 - 2.5e-12 46.5 0.0 4.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND90101.1 - 0.00018 21.3 0.1 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KND90101.1 - 0.15 11.6 0.2 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain TPT PF03151.11 KND90102.1 - 1.3e-33 115.8 20.0 1.5e-33 115.6 7.1 2.5 2 1 1 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KND90102.1 - 1.6e-07 30.5 17.5 5.7e-07 28.7 10.9 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 KND90102.1 - 0.0012 18.8 34.8 0.049 13.6 9.4 3.1 2 2 1 3 3 3 2 EamA-like transporter family NPCC PF08058.6 KND90102.1 - 0.037 13.8 0.2 0.089 12.6 0.2 1.6 1 0 0 1 1 1 0 Nuclear pore complex component CD99L2 PF12301.3 KND90102.1 - 4.2 7.0 9.3 0.14 11.8 2.0 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 GPI-anchored PF10342.4 KND90103.1 - 0.00074 19.9 0.1 0.0035 17.8 0.0 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CDC27 PF09507.5 KND90103.1 - 1 8.4 15.4 1.6 7.9 10.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Menin PF05053.8 KND90103.1 - 5.4 5.0 9.5 7.1 4.6 6.6 1.3 1 0 0 1 1 1 0 Menin DUF2514 PF10721.4 KND90103.1 - 6.4 6.4 11.5 4.3 7.0 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) SWI-SNF_Ssr4 PF08549.5 KND90104.1 - 1.7e-180 601.6 10.5 1.7e-180 601.6 7.3 1.4 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.14 KND90104.1 - 3.6e-133 443.2 0.0 5e-133 442.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KND90104.1 - 7.2e-52 175.5 0.0 1.8e-51 174.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KND90104.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GRASP55_65 PF04495.9 KND90105.1 - 3.6e-06 27.0 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KND90105.1 - 0.00031 20.5 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KND90105.1 - 0.0035 17.4 0.0 0.015 15.4 0.0 1.9 1 1 1 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PWI PF01480.12 KND90106.1 - 3.8e-28 97.4 0.0 5.4e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 PWI domain G-patch PF01585.18 KND90107.1 - 7.1e-06 25.7 0.0 3.3e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 G-patch domain Hydrolase_6 PF13344.1 KND90107.1 - 0.028 14.3 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MIP-T3 PF10243.4 KND90107.1 - 1.6 7.0 52.7 2.2 6.6 36.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3546 PF12066.3 KND90108.1 - 5.3e-26 90.7 1.9 5.3e-26 90.7 1.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KND90108.1 - 2e-23 81.7 0.1 6.2e-23 80.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KND90108.1 - 3e-05 24.3 3.4 3e-05 24.3 2.3 2.6 2 0 0 2 2 2 1 Arsenite-resistance protein 2 tRNA-synt_2d PF01409.15 KND90109.1 - 1e-82 277.0 0.0 1.4e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KND90109.1 - 6.7e-06 25.0 0.1 0.00017 20.4 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KND90109.1 - 0.0046 16.5 0.0 0.078 12.5 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ESR1_C PF12743.2 KND90110.1 - 0.37 10.3 2.5 0.73 9.4 1.8 1.5 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal RTC PF01137.16 KND90111.1 - 1.8e-30 105.4 0.1 2.5e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KND90111.1 - 2.2e-30 104.7 0.0 4.2e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.5 KND90112.1 - 1.2e-32 112.2 2.1 1.7e-32 111.7 1.4 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF1509 PF07420.6 KND90112.1 - 0.024 13.9 1.1 0.038 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 KND90112.1 - 0.043 12.7 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PPR_2 PF13041.1 KND90113.1 - 5.9e-14 51.7 0.0 6.2e-08 32.4 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 KND90113.1 - 4.7e-08 32.7 2.7 3 8.3 0.0 6.0 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 KND90113.1 - 4.7e-07 29.3 0.9 0.29 11.1 0.0 4.1 3 0 0 3 3 3 3 PPR repeat TPR_14 PF13428.1 KND90113.1 - 1.2e-05 25.4 0.2 0.088 13.4 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.2 KND90113.1 - 0.00058 19.2 0.4 4.7 6.7 0.1 4.2 4 0 0 4 4 4 1 PPR repeat TPR_16 PF13432.1 KND90113.1 - 0.00059 20.4 1.2 2 9.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND90113.1 - 0.012 15.9 0.1 0.54 10.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND90113.1 - 0.018 15.4 2.1 2.2 8.9 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND90113.1 - 0.018 14.7 0.1 18 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S9 PF00326.16 KND90114.1 - 1.1e-48 165.3 0.6 9.6e-47 158.9 0.4 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family NuA4 PF09340.5 KND90114.1 - 4e-21 74.4 0.1 1.1e-20 73.0 0.1 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Bromo_TP PF07524.8 KND90114.1 - 6.1e-11 41.8 0.0 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Abhydrolase_5 PF12695.2 KND90114.1 - 6.4e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family HTH_Tnp_Tc5 PF03221.11 KND90114.1 - 6.1e-09 35.5 0.2 2.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PD40 PF07676.7 KND90114.1 - 0.00016 21.2 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat TFIID-31kDa PF02291.10 KND90114.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CytochromB561_N PF09786.4 KND90114.1 - 4.6 5.5 9.9 6.8 5.0 6.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Clr5 PF14420.1 KND90115.1 - 1.9e-19 69.3 2.1 4.3e-19 68.1 1.5 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KND90115.1 - 2.3e-07 30.6 7.7 2.1e-05 24.3 1.4 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND90115.1 - 9.2e-05 21.9 0.7 0.031 14.0 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2852 PF11014.3 KND90115.1 - 0.0072 16.2 0.7 0.017 15.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) TPR_8 PF13181.1 KND90115.1 - 0.088 12.6 0.4 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND90115.1 - 0.31 11.7 16.5 2 9.2 0.1 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND90115.1 - 4.6 7.3 13.0 9.9 6.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DnaJ PF00226.26 KND90116.1 - 1.4e-07 31.1 0.1 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.4 KND90116.1 - 0.012 15.6 1.3 0.021 14.9 0.9 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.8 KND90116.1 - 0.032 14.2 0.5 0.047 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 KND90116.1 - 1.3 8.6 3.8 2.1 8.0 2.4 1.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain LSM PF01423.17 KND90117.1 - 1.8e-16 59.4 0.0 2.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 KND90118.1 - 1.5e-22 79.1 0.0 2.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KND90118.1 - 1.5e-21 75.9 0.1 4.4e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 CorA PF01544.13 KND90120.1 - 2.5e-12 46.4 2.0 4.7e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein APG6 PF04111.7 KND90120.1 - 0.028 13.4 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1206 PF06724.6 KND90120.1 - 0.2 11.4 0.7 0.62 9.8 0.5 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) PITH PF06201.8 KND90122.1 - 1.2e-36 125.7 0.0 1.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KND90122.1 - 5.4e-28 96.7 0.0 8.6e-28 96.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KND90122.1 - 1.4e-09 37.9 0.1 1.8e-07 31.1 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KND90122.1 - 4.1e-07 30.1 0.0 1.8e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KND90122.1 - 0.00017 21.2 0.0 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KND90122.1 - 0.00022 20.7 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KND90122.1 - 0.00044 19.8 0.1 0.0012 18.4 0.0 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 KND90122.1 - 0.0085 16.0 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Zn_clus PF00172.13 KND90123.1 - 0.00054 19.8 11.2 0.0012 18.7 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 KND90124.1 - 9.7e-43 145.3 0.4 4.1e-42 143.3 0.2 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KND90124.1 - 4.2e-09 36.5 0.0 9.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF3450 PF11932.3 KND90124.1 - 0.008 15.4 0.7 0.018 14.3 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PX PF00787.19 KND90124.1 - 0.081 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 PX domain DUF4229 PF14012.1 KND90125.1 - 2.3 8.1 13.3 38 4.2 5.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) CENP-K PF11802.3 KND90126.1 - 6.5e-11 41.9 1.8 0.00013 21.3 3.2 2.6 3 0 0 3 3 3 2 Centromere-associated protein K LUC7 PF03194.10 KND90126.1 - 0.16 11.4 5.7 0.15 11.5 1.0 2.1 2 0 0 2 2 2 0 LUC7 N_terminus CALCOCO1 PF07888.6 KND90126.1 - 0.25 9.5 10.4 0.053 11.8 4.3 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1690 PF07956.6 KND90126.1 - 0.91 9.4 11.2 0.47 10.4 4.4 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Ax_dynein_light PF10211.4 KND90126.1 - 6.4 6.5 15.4 14 5.4 0.4 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain DUF1349 PF07081.6 KND90127.1 - 2.8e-16 59.3 0.0 3.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ASCH PF04266.9 KND90127.1 - 0.0045 17.3 0.0 0.007 16.7 0.0 1.4 1 0 0 1 1 1 1 ASCH domain NYAP_C PF15452.1 KND90127.1 - 0.026 13.5 0.3 0.051 12.5 0.2 1.5 1 1 1 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Peptidase_S9 PF00326.16 KND90128.1 - 1.6e-24 86.3 0.0 7.4e-24 84.1 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND90128.1 - 0.0035 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABM PF03992.11 KND90129.1 - 2e-06 27.7 0.1 0.00014 21.8 0.1 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 KND90129.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Exo_endo_phos PF03372.18 KND90130.1 - 3.7e-20 72.9 0.3 6e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spo7 PF03907.8 KND90130.1 - 0.0024 17.5 0.2 0.004 16.7 0.2 1.3 1 0 0 1 1 1 1 Spo7-like protein KH_1 PF00013.24 KND90132.1 - 6.9e-38 128.1 1.7 2.3e-15 55.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KND90132.1 - 4.5e-30 102.7 9.3 1.4e-11 43.7 1.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KND90132.1 - 1.8e-12 46.6 5.2 0.0028 17.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KND90132.1 - 2.5e-06 27.0 0.2 0.5 10.0 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KND90132.1 - 0.00023 20.9 4.9 0.39 10.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain BTB PF00651.26 KND90134.1 - 1.4e-07 31.4 0.0 4.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Proteasome PF00227.21 KND90135.1 - 2.1e-31 108.6 0.0 2.9e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit HMG_box_2 PF09011.5 KND90136.1 - 5.3e-06 26.7 0.2 5.3e-06 26.7 0.1 2.9 3 0 0 3 3 3 1 HMG-box domain HMG_box PF00505.14 KND90136.1 - 1.1e-05 25.5 0.1 1.1e-05 25.5 0.1 2.9 3 2 1 4 4 4 1 HMG (high mobility group) box Med3 PF11593.3 KND90136.1 - 0.021 14.0 9.0 0.03 13.5 6.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YdjC PF04794.7 KND90136.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 YdjC-like protein RIB43A PF05914.7 KND90136.1 - 2.1 6.8 10.1 0.098 11.2 0.3 2.4 2 1 0 2 2 2 0 RIB43A AAA PF00004.24 KND90137.1 - 1.4e-42 144.9 0.0 2.5e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND90137.1 - 1.1e-07 32.0 0.0 6.4e-06 26.2 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KND90137.1 - 1.8e-06 27.7 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND90137.1 - 2.5e-06 27.5 0.0 7.7e-06 25.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KND90137.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KND90137.1 - 7.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KND90137.1 - 0.0002 20.3 0.0 0.00058 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KND90137.1 - 0.00032 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KND90137.1 - 0.00059 20.6 0.8 0.002 18.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KND90137.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KND90137.1 - 0.0018 17.0 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KND90137.1 - 0.0019 18.5 0.2 0.0083 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF4200 PF13863.1 KND90137.1 - 0.0019 18.1 2.6 0.0043 16.9 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) IstB_IS21 PF01695.12 KND90137.1 - 0.0022 17.4 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KND90137.1 - 0.0023 17.8 0.0 0.0063 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KND90137.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KND90137.1 - 0.0044 16.6 0.4 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KND90137.1 - 0.0047 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 KND90137.1 - 0.005 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 KND90137.1 - 0.0075 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 KND90137.1 - 0.0088 15.4 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KND90137.1 - 0.0095 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KND90137.1 - 0.018 15.0 0.0 0.059 13.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KND90137.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KND90137.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KND90137.1 - 0.026 14.2 0.1 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase ResIII PF04851.10 KND90137.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KND90137.1 - 0.03 13.4 0.6 0.11 11.5 0.0 2.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 KND90137.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein eIF-1a PF01176.14 KND90137.1 - 0.036 13.4 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 NACHT PF05729.7 KND90137.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 KND90137.1 - 0.045 13.3 0.2 0.099 12.2 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KND90137.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KND90137.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KND90137.1 - 0.43 10.8 6.7 2.7 8.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain DivIC PF04977.10 KND90137.1 - 0.52 9.8 3.1 3.7 7.1 1.0 2.7 2 0 0 2 2 2 0 Septum formation initiator SIS PF01380.17 KND90138.1 - 1.1e-54 183.5 0.0 3.1e-29 101.2 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KND90138.1 - 1.5e-26 93.0 0.0 6.2e-18 64.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KND90138.1 - 3.1e-19 69.2 0.0 7.1e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KND90138.1 - 7.1e-11 41.9 0.0 1.9e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KND90138.1 - 3.5e-08 32.4 0.0 5.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UCR_UQCRX_QCR9 PF05365.7 KND90139.1 - 3.6e-23 80.9 2.0 3.9e-23 80.8 1.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 KND90140.1 - 3.4e-14 52.0 2.9 6.5e-14 51.1 2.0 1.5 1 0 0 1 1 1 1 Mago binding CRC_subunit PF08624.5 KND90142.1 - 1.3e-57 193.6 0.0 2.7e-57 192.5 0.0 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.9 KND90142.1 - 1.5 6.7 4.7 2 6.3 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-UBR PF02207.15 KND90143.1 - 6.8e-17 60.9 16.3 6.8e-17 60.9 11.3 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KND90143.1 - 5.4e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CAP_N PF01213.14 KND90143.1 - 0.76 8.9 2.6 1.4 8.1 1.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TFIIA PF03153.8 KND90143.1 - 3.3 7.5 15.9 0.32 10.8 6.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nefa_Nip30_N PF10187.4 KND90144.1 - 6.1e-22 77.7 16.0 6.1e-22 77.7 11.1 2.3 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 YcbB PF08664.5 KND90144.1 - 0.11 12.2 1.7 0.21 11.3 1.2 1.4 1 0 0 1 1 1 0 YcbB domain Nucleo_P87 PF07267.6 KND90144.1 - 4.6 5.8 7.0 7.5 5.1 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MIF4G_like_2 PF09090.6 KND90144.1 - 7.3 5.7 7.7 2.3 7.3 3.6 1.4 2 0 0 2 2 2 0 MIF4G like Flagellar_rod PF05149.7 KND90144.1 - 9 5.3 16.3 13 4.8 11.3 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Cyclin PF08613.6 KND90145.1 - 5.8e-12 46.2 0.0 1.4e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin CHD5 PF04420.9 KND90145.1 - 0.56 9.8 3.8 0.43 10.2 0.3 2.1 1 1 1 2 2 2 0 CHD5-like protein ADH_zinc_N PF00107.21 KND90146.1 - 2.8e-10 39.8 0.0 6.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND90146.1 - 2.3e-05 24.0 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 KND90147.1 - 6.8e-09 35.4 11.6 1.2e-08 34.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TALPID3 PF15324.1 KND90147.1 - 2.5 5.3 3.6 3.4 4.9 2.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Cys_Met_Meta_PP PF01053.15 KND90148.1 - 1.5e-138 461.2 0.1 1.7e-138 461.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KND90148.1 - 7.9e-08 31.4 1.4 5.1e-07 28.7 0.2 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KND90148.1 - 5.8e-07 28.7 0.1 9.6e-07 28.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KND90148.1 - 0.00012 21.2 0.3 0.00022 20.3 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 KND90148.1 - 0.0024 16.6 0.1 0.0024 16.6 0.1 1.4 2 0 0 2 2 2 1 Glycine cleavage system P-protein 2-Hacid_dh PF00389.25 KND90148.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F-box PF00646.28 KND90149.1 - 0.014 15.0 0.5 0.076 12.6 0.2 2.5 2 0 0 2 2 2 0 F-box domain DUF2217 PF10265.4 KND90151.1 - 0.0082 14.9 0.3 0.011 14.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) SKG6 PF08693.5 KND90151.1 - 0.019 14.3 0.6 0.04 13.2 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Chromate_transp PF02417.10 KND90151.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.1 1 0 0 1 1 1 0 Chromate transporter TMEM154 PF15102.1 KND90151.1 - 0.17 11.6 0.2 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family HLH PF00010.21 KND90152.1 - 9.6e-13 47.6 1.4 1.7e-12 46.8 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TPR_11 PF13414.1 KND90153.1 - 4.1e-24 84.0 6.2 2.8e-10 39.6 0.3 4.6 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 KND90153.1 - 4.9e-22 76.0 4.0 2.5e-06 26.9 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KND90153.1 - 3.7e-21 73.7 2.5 1.8e-06 27.3 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KND90153.1 - 8e-18 63.3 6.6 5.4e-05 23.4 0.0 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KND90153.1 - 5.5e-15 54.2 4.9 0.019 15.1 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KND90153.1 - 9e-15 54.8 6.8 4.5e-05 24.0 0.0 5.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND90153.1 - 5.5e-13 48.6 2.2 9.9e-07 28.6 0.0 4.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KND90153.1 - 3.5e-12 46.4 12.6 0.00067 19.9 0.1 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KND90153.1 - 1.9e-10 39.6 0.7 0.0013 18.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND90153.1 - 7.8e-10 37.8 0.6 0.012 15.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND90153.1 - 1.8e-07 31.1 1.4 8.8 7.0 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND90153.1 - 2.1e-07 30.6 1.5 0.046 13.5 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KND90153.1 - 7e-07 29.2 8.3 0.0046 17.0 0.1 5.0 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.1 KND90153.1 - 0.0001 21.4 6.3 0.12 11.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 KND90153.1 - 0.016 14.9 0.0 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1641 PF07849.6 KND90153.1 - 0.14 11.7 0.2 0.37 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_10 PF13374.1 KND90153.1 - 0.31 11.0 6.4 0.88 9.5 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Brix PF04427.13 KND90154.1 - 2.3e-37 128.5 0.0 3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Fungal_trans_2 PF11951.3 KND90155.1 - 2.9e-06 26.1 0.7 4.3e-06 25.5 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90155.1 - 0.97 9.3 14.6 0.31 10.9 1.6 2.6 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC3_N PF07034.6 KND90156.1 - 6.4e-14 51.6 1.2 6.3e-13 48.3 0.1 2.8 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus PWWP PF00855.12 KND90157.1 - 2.6e-14 53.1 0.0 1.3e-13 50.9 0.0 2.3 1 0 0 1 1 1 1 PWWP domain CPSase_L_D2 PF02786.12 KND90158.1 - 3.7e-109 362.9 0.0 2.1e-84 282.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KND90158.1 - 2.3e-41 140.3 0.2 4.5e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KND90158.1 - 3.4e-37 127.9 0.1 1.7e-19 70.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KND90158.1 - 1.1e-35 122.0 0.0 1.4e-16 60.5 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KND90158.1 - 2.6e-24 85.5 0.0 3.5e-08 32.5 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KND90158.1 - 4.6e-20 71.6 0.2 2.9e-09 36.5 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KND90158.1 - 1.6e-16 60.3 0.3 4.9e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KND90158.1 - 1.6e-09 37.5 0.0 0.00011 21.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KND90158.1 - 1e-06 28.7 0.5 0.0056 16.5 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 KND90158.1 - 3.6e-05 23.4 0.4 0.16 11.4 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KND90158.1 - 0.00025 20.3 0.0 0.058 12.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain EAP30 PF04157.11 KND90158.1 - 0.094 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family Pox_I6 PF04595.8 KND90158.1 - 0.21 10.2 0.0 0.36 9.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus I6-like family NPL4 PF05021.10 KND90159.1 - 9e-126 419.1 0.0 1.1e-125 418.8 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KND90159.1 - 2e-65 218.9 0.0 2.9e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KND90159.1 - 0.0025 18.0 0.0 0.009 16.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 KND90160.1 - 3.5e-76 254.8 0.0 4.2e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 HpcH_HpaI PF03328.9 KND90162.1 - 3e-34 117.8 0.0 3.9e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.4 KND90162.1 - 0.00084 18.2 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) SHS2_Rpb7-N PF03876.12 KND90163.1 - 4.5e-15 55.5 0.0 8.2e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KND90163.1 - 2.9e-13 49.6 0.0 4.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 KND90164.1 - 3.9e-29 100.3 0.7 8e-29 99.3 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) PufQ PF05398.6 KND90164.1 - 0.09 12.8 0.6 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 PufQ cytochrome subunit TMEM169 PF15052.1 KND90164.1 - 0.29 11.0 4.2 0.46 10.3 2.9 1.4 1 1 0 1 1 1 0 TMEM169 protein family DUF3852 PF12963.2 KND90164.1 - 1.4 9.0 6.2 0.86 9.6 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) Formyl_trans_N PF00551.14 KND90165.1 - 2.6e-28 98.8 0.0 3.7e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Glycophorin_A PF01102.13 KND90166.1 - 0.056 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A Ribosomal_L6 PF00347.18 KND90167.1 - 5.3e-27 94.1 6.8 4.7e-13 49.4 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HSP20 PF00011.16 KND90168.1 - 5.7e-16 58.2 0.1 5.6e-12 45.4 0.1 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family YTH PF04146.10 KND90168.1 - 3.2e-12 46.2 0.0 5.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KND90168.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 KND90169.1 - 4.3e-19 68.5 0.1 8.9e-19 67.5 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit Vps26 PF03643.10 KND90170.1 - 6.7e-130 431.7 0.7 7.6e-130 431.6 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KND90170.1 - 4.8e-05 23.2 0.0 0.029 14.1 0.0 3.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rad51 PF08423.6 KND90171.1 - 2.4e-137 455.9 0.0 3.2e-137 455.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KND90171.1 - 6.6e-13 48.5 0.0 9.5e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KND90171.1 - 6.5e-07 28.7 0.0 9.6e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KND90171.1 - 6.6e-07 29.4 0.5 2.1e-06 27.7 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 KND90171.1 - 5.8e-05 22.3 0.0 9.7e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 KND90171.1 - 0.016 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2146 PF10220.4 KND90172.1 - 0.46 8.4 4.5 0.75 7.7 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PRP1_N PF06424.7 KND90172.1 - 9.9 6.4 15.9 16 5.7 8.1 2.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PI3_PI4_kinase PF00454.22 KND90174.1 - 1.2e-39 136.1 0.0 4.1e-39 134.4 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KND90174.1 - 6.6e-23 80.8 0.0 1.6e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.16 KND90175.1 - 5.7e-30 104.3 11.6 7e-30 104.0 8.1 1.1 1 0 0 1 1 1 1 Cation efflux family Lum_binding PF00677.12 KND90176.1 - 2.6e-39 132.9 0.1 2.1e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.10 KND90177.1 - 1.3e-31 109.2 0.2 2.3e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KND90177.1 - 1.8e-05 24.7 0.0 6.4e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KND90177.1 - 0.042 14.0 0.0 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain T2SK PF03934.8 KND90177.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K PGM_PMM_I PF02878.11 KND90178.1 - 1e-17 63.8 0.3 5.5e-08 32.3 0.0 3.2 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KND90178.1 - 5.4e-10 39.5 0.3 3.4e-09 36.9 0.2 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KND90178.1 - 9e-10 38.4 0.2 3.3e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KND90178.1 - 0.0069 16.4 0.1 0.032 14.2 0.1 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Ribosomal_S8e PF01201.17 KND90181.1 - 5.8e-34 117.0 7.3 2.6e-33 114.9 5.1 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.16 KND90182.1 - 0.0041 17.2 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 KND90183.1 - 1.8e-45 155.1 0.0 2.8e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90183.1 - 4.4e-20 71.8 0.0 6.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND90183.1 - 0.00017 20.6 0.0 0.00082 18.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like HLH PF00010.21 KND90184.1 - 3.3e-13 49.0 0.3 6.2e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_12 PF13424.1 KND90185.1 - 4.5e-15 55.3 0.2 4.7e-07 29.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND90185.1 - 3e-11 43.5 2.6 0.001 19.3 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND90185.1 - 5e-11 42.9 2.5 0.0018 18.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND90185.1 - 5.9e-11 41.4 4.5 1.5e-05 24.5 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND90185.1 - 1.7e-10 40.4 0.0 5.7e-05 22.6 0.0 3.4 3 1 2 5 5 5 3 TPR repeat TPR_7 PF13176.1 KND90185.1 - 2.9e-09 36.0 0.4 4.4e-05 22.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND90185.1 - 1.5e-08 34.5 8.7 0.47 11.2 0.1 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND90185.1 - 5.5e-08 32.0 0.0 0.00016 21.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KND90185.1 - 3.8e-06 26.6 5.2 0.019 14.9 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KND90185.1 - 4.8e-05 23.4 0.0 1.8 8.7 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KND90185.1 - 0.0001 21.7 0.0 0.0017 17.9 0.0 3.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND90185.1 - 0.0002 21.3 0.0 35 4.9 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND90185.1 - 0.0018 18.5 0.4 0.24 11.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KND90185.1 - 0.0024 17.7 0.5 1.6 8.6 0.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KND90185.1 - 0.0028 17.4 2.3 5.6 6.9 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KND90185.1 - 0.0034 17.7 4.1 2.9 8.5 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat RWD PF05773.17 KND90186.1 - 4.6e-24 84.4 0.1 7.4e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 RWD domain KfrA_N PF11740.3 KND90186.1 - 0.26 11.7 9.0 1.3 9.4 3.1 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term PP2C PF00481.16 KND90187.1 - 3.3e-56 190.5 0.0 5.4e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KND90187.1 - 1.1e-50 168.4 49.5 2.4e-07 30.2 0.3 12.4 5 4 9 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND90187.1 - 1.1e-40 137.1 48.4 7.8e-10 38.3 0.1 9.7 4 3 8 12 12 12 11 Leucine rich repeat Guanylate_cyc PF00211.15 KND90187.1 - 7e-33 113.5 0.0 1.6e-32 112.3 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KND90187.1 - 1.6e-28 94.3 42.7 0.16 12.1 0.0 19.7 19 1 1 20 20 20 9 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 KND90187.1 - 1.4e-22 78.7 1.5 5.3e-22 76.8 1.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 KND90187.1 - 1.8e-16 57.3 39.7 0.55 10.6 0.1 17.4 19 0 0 19 19 19 3 Leucine rich repeat RA PF00788.18 KND90187.1 - 2.8e-07 30.9 0.1 1.9e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 KND90187.1 - 4.5e-07 29.2 38.9 5.5 7.3 0.1 15.1 16 2 1 17 17 17 1 Leucine Rich repeat LRR_9 PF14580.1 KND90187.1 - 0.095 12.2 9.0 5.7 6.4 0.2 4.0 3 1 1 4 4 4 0 Leucine-rich repeat Glyco_transf_22 PF03901.12 KND90188.1 - 7.4e-41 140.5 13.5 9.7e-41 140.1 9.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Alpha-amylase PF00128.19 KND90189.1 - 3.8e-99 332.0 0.1 6.9e-99 331.2 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KND90189.1 - 0.0015 18.5 0.0 0.0063 16.6 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain DUF3459 PF11941.3 KND90189.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 KND90189.1 - 0.045 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme RTC4 PF14474.1 KND90190.1 - 2.1e-28 98.7 0.0 4.3e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain ThiS PF02597.15 KND90191.1 - 3.9e-09 36.8 0.0 4.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family Dynamitin PF04912.9 KND90192.1 - 6.7e-37 127.2 10.0 7.3e-36 123.7 7.0 2.3 1 1 0 1 1 1 1 Dynamitin Flagellin_N PF00669.15 KND90192.1 - 0.019 14.7 0.5 0.019 14.7 0.3 3.2 3 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region BAAT_C PF08840.6 KND90192.1 - 0.026 14.2 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3450 PF11932.3 KND90192.1 - 0.12 11.6 10.1 0.88 8.7 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) FH2 PF02181.18 KND90192.1 - 0.21 10.4 4.7 5.7 5.7 0.1 3.1 3 0 0 3 3 3 0 Formin Homology 2 Domain Prefoldin_2 PF01920.15 KND90192.1 - 0.42 10.3 8.7 4.6 7.0 0.3 3.6 3 0 0 3 3 3 0 Prefoldin subunit COG2 PF06148.6 KND90192.1 - 0.48 10.3 5.2 7.4 6.4 0.1 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 KND90192.1 - 0.51 10.1 4.8 12 5.7 0.5 3.0 3 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KND90192.1 - 0.6 10.2 7.4 11 6.0 0.5 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.5 KND90192.1 - 0.61 9.8 3.5 0.94 9.2 0.1 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GrpE PF01025.14 KND90192.1 - 1.2 8.6 8.7 6.7 6.2 0.4 3.6 2 1 1 3 3 3 0 GrpE Cluap1 PF10234.4 KND90192.1 - 2.2 7.3 7.4 1 8.4 0.1 2.9 3 0 0 3 3 3 0 Clusterin-associated protein-1 DUF1192 PF06698.6 KND90192.1 - 2.4 8.0 14.2 0.86 9.4 2.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) HWE_HK PF07536.9 KND90192.1 - 2.9 8.3 7.8 0.5 10.8 0.4 3.5 4 1 0 4 4 4 0 HWE histidine kinase IFT57 PF10498.4 KND90192.1 - 3.4 6.3 10.3 0.26 10.0 0.1 2.9 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Phage_GP20 PF06810.6 KND90192.1 - 5.6 6.3 11.6 0.4 10.1 0.4 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 FliD_N PF02465.13 KND90192.1 - 7.3 7.0 9.7 3 8.2 1.4 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Spc24 PF08286.6 KND90192.1 - 8.2 6.1 11.6 6.3 6.5 0.1 3.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 GFA PF04828.9 KND90194.1 - 1.3e-21 76.2 0.3 5.9e-10 38.9 0.0 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 KND90194.1 - 3.6 7.5 9.5 0.37 10.7 2.5 2.4 3 0 0 3 3 3 0 Cysteine-rich CWC Dus PF01207.12 KND90195.1 - 1.6e-26 92.8 0.4 2.5e-23 82.4 0.0 3.0 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) IBR PF01485.16 KND90195.1 - 3.2e-05 23.7 24.5 6.1e-05 22.8 9.0 2.9 3 0 0 3 3 3 2 IBR domain FAA_hydrolase PF01557.13 KND90196.1 - 8.6e-62 208.4 0.0 1e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 14-3-3 PF00244.15 KND90197.1 - 7.1e-114 378.7 2.9 9.4e-114 378.3 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 KND90197.1 - 0.02 14.4 0.7 9.2 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF4085 PF13315.1 KND90197.1 - 0.028 13.7 0.2 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) TPR_12 PF13424.1 KND90197.1 - 0.047 13.6 0.3 6.5 6.7 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat MCM_N PF14551.1 KND90197.1 - 0.25 11.8 1.2 5 7.6 0.8 2.3 1 1 0 1 1 1 0 MCM N-terminal domain Syja_N PF02383.13 KND90199.1 - 3.3e-82 275.8 0.0 4.7e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KND90199.1 - 1.4e-25 90.6 0.1 2.6e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_16 PF13432.1 KND90200.1 - 1.1e-08 35.4 0.2 0.036 14.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND90200.1 - 3.7e-07 30.1 3.0 1.8 9.4 0.0 6.9 4 3 3 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 KND90200.1 - 6e-05 22.9 0.8 0.0022 17.7 0.1 2.9 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_17 PF13431.1 KND90200.1 - 0.0011 18.9 0.0 2.3 8.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KND90200.1 - 0.0024 16.8 0.8 2.7 6.7 0.0 3.5 2 1 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 KND90200.1 - 0.0076 16.5 0.0 0.12 12.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat peroxidase PF00141.18 KND90201.1 - 3.7e-47 160.7 0.0 6e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Oxidored_FMN PF00724.15 KND90202.1 - 1.6e-69 234.5 0.0 2e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AIRC PF00731.15 KND90203.1 - 1.1e-59 200.0 1.9 2.3e-59 198.9 1.3 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KND90203.1 - 3.8e-48 163.0 0.0 1.7e-47 160.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KND90203.1 - 4.5e-11 42.8 0.1 9.7e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KND90203.1 - 2.3e-06 27.1 0.0 6.2e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KND90203.1 - 0.0018 17.1 0.0 0.005 15.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 KND90203.1 - 0.065 12.6 0.2 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Propionate catabolism activator CoA_binding_2 PF13380.1 KND90203.1 - 0.091 12.9 4.3 3.9 7.6 0.0 4.1 3 2 2 5 5 5 0 CoA binding domain Thioredoxin PF00085.15 KND90204.1 - 1.6e-65 217.2 9.4 1.5e-32 111.3 0.1 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 KND90204.1 - 1.4e-54 184.7 4.0 3.5e-41 141.0 1.1 3.6 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND90204.1 - 1.3e-11 44.4 0.8 0.00079 19.4 0.0 4.5 3 1 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KND90204.1 - 2.6e-11 43.3 0.0 2.8e-05 24.0 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KND90204.1 - 2.6e-10 40.4 5.7 0.00014 21.9 0.1 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KND90204.1 - 1.2e-07 31.4 1.5 0.0039 16.8 0.1 3.2 3 1 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 KND90204.1 - 1.3e-07 30.7 1.0 1.3e-07 30.7 0.7 2.1 2 0 0 2 2 2 1 Calsequestrin ERp29_N PF07912.8 KND90204.1 - 7.9e-07 29.0 1.1 3.5 7.5 0.0 4.4 4 0 0 4 4 4 3 ERp29, N-terminal domain Redoxin PF08534.5 KND90204.1 - 2.8e-06 26.9 3.2 0.0062 16.0 0.1 3.5 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 KND90204.1 - 0.0055 16.4 0.7 0.036 13.8 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin domain DSBA PF01323.15 KND90204.1 - 0.046 13.2 0.1 11 5.5 0.0 3.1 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Toprim_3 PF13362.1 KND90204.1 - 0.13 12.4 1.0 0.56 10.4 0.0 2.5 3 0 0 3 3 2 0 Toprim domain Thioredoxin_4 PF13462.1 KND90204.1 - 0.2 11.6 13.8 8.5 6.3 0.1 4.4 3 2 0 3 3 3 0 Thioredoxin DUF3186 PF11382.3 KND90204.1 - 3 6.9 6.3 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) Band_7 PF01145.20 KND90205.1 - 2.1e-23 83.1 2.7 3.3e-23 82.5 1.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Elongin_A PF06881.6 KND90206.1 - 6.4e-17 61.9 2.1 1.3e-16 60.9 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RNA_pol_Rpb4 PF03874.11 KND90207.1 - 3.5e-29 101.1 4.8 4.1e-29 100.9 3.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.1 KND90207.1 - 0.01 15.8 1.5 0.013 15.4 0.3 1.8 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Sybindin PF04099.7 KND90208.1 - 3.8e-50 169.3 0.0 4.6e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KND90208.1 - 8.7e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region CPL PF08144.6 KND90209.1 - 1.1e-16 61.0 0.6 3.1e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 CPL (NUC119) domain TraH_2 PF06871.6 KND90209.1 - 4.7 6.5 8.1 0.11 11.9 0.3 2.0 2 0 0 2 2 2 0 TraH_2 SUI1 PF01253.17 KND90211.1 - 4.2e-19 68.1 0.8 2.2e-18 65.8 0.6 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 HrpA_pilin PF09589.5 KND90211.1 - 0.025 14.9 1.0 0.043 14.2 0.7 1.4 1 0 0 1 1 1 0 HrpA pilus formation protein Glyco_transf_49 PF13896.1 KND90211.1 - 0.04 13.0 1.0 0.053 12.6 0.1 1.7 2 0 0 2 2 2 0 Glycosyl-transferase for dystroglycan Methyltransf_11 PF08241.7 KND90212.1 - 1.1e-11 45.0 0.0 2.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND90212.1 - 0.00027 20.6 0.0 0.00064 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND90212.1 - 0.0077 16.6 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90212.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain VGCC_beta4Aa_N PF12052.3 KND90212.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal VWA_2 PF13519.1 KND90213.1 - 8.5e-16 58.5 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KND90213.1 - 3e-08 33.4 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KND90213.1 - 3.2e-08 33.4 0.4 4.6e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KND90213.1 - 0.0018 17.6 2.0 0.0018 17.6 1.4 2.7 3 0 0 3 3 3 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 KND90214.1 - 1.2e-24 85.3 3.4 2e-24 84.7 2.3 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal ATP-synt_ab PF00006.20 KND90215.1 - 5.4e-69 231.9 0.0 8.2e-69 231.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KND90215.1 - 2.9e-26 92.1 0.7 6.3e-26 91.0 0.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KND90215.1 - 3.2e-15 56.0 2.4 6.9e-15 55.0 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KND90215.1 - 0.0035 17.2 1.0 0.0081 16.0 0.5 1.8 2 0 0 2 2 2 1 HAS barrel domain DNA_gyraseA_C PF03989.8 KND90216.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.6 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller NAD_kinase PF01513.16 KND90217.1 - 1.5e-70 237.2 0.0 2.1e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 KND90218.1 - 2.2e-11 44.1 0.0 3.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KND90218.1 - 0.0095 15.8 0.1 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UPF0731 PF14982.1 KND90218.1 - 0.081 12.8 0.2 6.6 6.7 0.0 2.6 3 0 0 3 3 3 0 UPF0731 family Ras PF00071.17 KND90219.1 - 3.2e-49 166.4 0.0 3.9e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND90219.1 - 3.6e-15 56.5 0.0 6.9e-15 55.6 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KND90219.1 - 1.4e-10 40.6 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KND90219.1 - 0.00047 20.3 0.1 0.003 17.7 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KND90219.1 - 0.0019 17.4 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KND90219.1 - 0.019 14.2 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 KND90219.1 - 0.034 12.8 2.0 0.42 9.2 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 KND90219.1 - 0.079 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KND90219.1 - 0.082 12.1 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KND90219.1 - 0.092 12.8 0.3 0.42 10.7 0.1 1.9 1 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KND90219.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KND90219.1 - 0.16 11.0 0.2 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 KaiC Homeobox PF00046.24 KND90220.1 - 2.1e-13 49.6 2.4 5.2e-13 48.4 1.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KND90220.1 - 0.045 13.4 0.2 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Carb_kinase PF01256.12 KND90222.1 - 1.8e-51 174.7 0.0 2.2e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KND90222.1 - 0.019 14.2 0.0 0.046 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase FKBP_C PF00254.23 KND90225.1 - 1.2e-30 105.3 0.0 3.6e-30 103.8 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.20 KND90226.1 - 2.9e-41 141.3 0.0 1.4e-32 112.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND90226.1 - 2.9e-19 69.1 0.0 1.5e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KND90226.1 - 0.0027 17.4 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND90226.1 - 0.057 12.3 0.0 0.53 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 KND90226.1 - 0.11 11.2 0.1 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RabGAP-TBC PF00566.13 KND90227.1 - 7.6e-32 110.5 0.0 7.1e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FimP PF09766.4 KND90228.1 - 2.7e-26 92.4 11.2 3.7e-26 92.0 7.8 1.2 1 0 0 1 1 1 1 Fms-interacting protein Methyltransf_21 PF05050.7 KND90228.1 - 0.049 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain K-box PF01486.12 KND90228.1 - 0.25 11.1 13.9 0.21 11.4 6.7 2.9 1 1 1 2 2 2 0 K-box region CENP-F_leu_zip PF10473.4 KND90228.1 - 0.31 10.8 13.4 0.62 9.9 3.7 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF406 PF04175.7 KND90228.1 - 0.71 10.3 0.1 0.71 10.3 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF406) Pinin_SDK_memA PF04696.8 KND90228.1 - 1.9 8.0 13.1 0.98 9.0 3.9 2.5 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF4200 PF13863.1 KND90228.1 - 2.7 7.9 16.1 9 6.2 2.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-H PF05837.7 KND90228.1 - 2.7 8.1 12.1 6.7 6.9 0.1 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Flagellin_N PF00669.15 KND90228.1 - 3.3 7.5 7.6 1.6 8.4 1.1 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF972 PF06156.8 KND90228.1 - 5.3 7.4 8.3 7.8 6.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Glyco_trans_2_3 PF13632.1 KND90229.1 - 6.6e-18 65.1 0.6 6.6e-18 65.1 0.4 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 DUF4066 PF13278.1 KND90230.1 - 6.1e-15 54.8 0.0 7.4e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KND90230.1 - 0.00027 20.3 0.0 0.00059 19.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DUF605 PF04652.11 KND90231.1 - 4 6.7 8.1 4.4 6.6 5.6 1.1 1 0 0 1 1 1 0 Vta1 like WLM PF08325.5 KND90232.1 - 2.6e-41 141.5 0.8 2.6e-41 141.5 0.6 1.8 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KND90232.1 - 3.9e-07 30.0 0.8 3.9e-07 30.0 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 DUF2890 PF11081.3 KND90232.1 - 0.31 11.0 7.5 0.051 13.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Sulfate_transp PF00916.15 KND90233.1 - 5.3e-75 252.0 6.6 8.6e-75 251.3 4.6 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KND90233.1 - 2e-31 107.4 4.3 2e-31 107.4 3.0 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KND90233.1 - 5e-08 32.3 0.0 9.7e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain HlyIII PF03006.15 KND90234.1 - 2.5e-55 187.3 20.2 3.1e-55 187.0 14.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3681 PF12442.3 KND90234.1 - 0.081 13.1 3.4 4.6 7.4 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) PNP_UDP_1 PF01048.15 KND90235.1 - 0.002 17.1 0.5 0.0026 16.7 0.4 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily Shisa PF13908.1 KND90236.1 - 0.00041 20.5 7.7 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator DUF1294 PF06961.8 KND90236.1 - 0.39 10.6 3.9 0.51 10.3 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1294) Pex14_N PF04695.8 KND90236.1 - 9.5 6.2 19.3 27 4.8 5.7 3.6 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CsbD PF05532.7 KND90238.1 - 1.3e-09 37.5 9.2 7.6e-05 22.3 0.9 2.1 1 1 1 2 2 2 2 CsbD-like Peptidase_S24 PF00717.18 KND90239.1 - 5.3e-07 29.1 0.0 7.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like AAA PF00004.24 KND90240.1 - 1.2e-16 61.1 0.0 4.6e-16 59.2 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KND90240.1 - 9.9e-13 48.0 0.0 5.4e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KND90240.1 - 4.7e-12 45.7 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KND90240.1 - 2.2e-11 43.1 0.0 1.3e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KND90240.1 - 3.3e-07 30.5 0.1 8.4e-05 22.7 0.0 3.3 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KND90240.1 - 1.5e-05 24.2 0.0 3.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KND90240.1 - 2e-05 24.2 0.0 5.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KND90240.1 - 4.4e-05 23.1 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KND90240.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KND90240.1 - 0.00012 22.1 0.0 0.002 18.1 0.0 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KND90240.1 - 0.0003 20.6 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KND90240.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KND90240.1 - 0.0014 17.8 0.0 0.051 12.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KND90240.1 - 0.0043 16.5 0.0 0.043 13.2 0.0 2.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_24 PF13479.1 KND90240.1 - 0.005 16.4 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND90240.1 - 0.0061 17.3 0.0 0.013 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND90240.1 - 0.0093 15.3 0.1 0.032 13.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KND90240.1 - 0.01 15.4 0.0 0.053 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KND90240.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KND90240.1 - 0.017 14.8 0.1 0.16 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KND90240.1 - 0.022 13.4 0.0 0.56 8.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 KND90240.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KND90240.1 - 0.029 14.6 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND90240.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KND90240.1 - 0.057 13.0 0.0 0.47 10.0 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KND90240.1 - 0.096 12.8 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KND90240.1 - 0.11 11.9 0.0 0.63 9.4 0.0 2.2 1 1 0 1 1 1 0 AAA-like domain Parvo_NS1 PF01057.12 KND90240.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SNF2_N PF00176.18 KND90240.1 - 0.13 11.0 0.0 2 7.1 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain Sec63 PF02889.11 KND90242.1 - 8.5e-195 646.0 0.0 5.1e-110 367.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KND90242.1 - 6.8e-41 139.5 0.1 3.2e-25 88.5 0.1 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KND90242.1 - 7.2e-12 45.5 0.2 6.2e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KND90242.1 - 5.7e-10 38.9 0.0 4.9e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KND90242.1 - 0.00045 20.3 0.1 0.035 14.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KND90242.1 - 0.0026 17.2 0.0 4.2 6.7 0.0 4.0 2 2 0 3 3 3 2 AAA-like domain TFIIE_alpha PF02002.12 KND90242.1 - 0.0041 16.6 0.2 3.3 7.2 0.0 3.1 2 0 0 2 2 2 2 TFIIE alpha subunit DUF2417 PF10329.4 KND90244.1 - 4.8e-81 271.5 2.3 6.5e-81 271.1 1.6 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KND90244.1 - 0.00019 21.3 0.9 0.00038 20.3 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3357 PF11837.3 KND90244.1 - 4.1 7.3 10.6 1.5 8.6 0.0 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF3357) RhoGAP PF00620.22 KND90245.1 - 2.4e-35 121.4 0.0 5.1e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KND90245.1 - 1.3e-28 98.8 43.2 6e-12 45.4 4.6 4.9 5 0 0 5 5 5 4 LIM domain UQ_con PF00179.21 KND90246.1 - 4.1e-44 149.4 0.0 3.8e-29 100.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND90246.1 - 0.003 17.3 0.0 0.034 13.9 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KND90246.1 - 0.0039 17.0 0.0 0.68 9.8 0.0 2.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KND90246.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain 3Beta_HSD PF01073.14 KND90248.1 - 3.6e-65 219.4 0.0 4.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KND90248.1 - 3.3e-31 108.5 0.3 4.8e-31 107.9 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KND90248.1 - 1.3e-17 63.6 0.8 1.8e-17 63.1 0.5 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KND90248.1 - 1.5e-15 57.6 0.8 2e-15 57.2 0.6 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND90248.1 - 2.1e-14 53.0 0.1 3.4e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KND90248.1 - 9.1e-07 28.0 0.7 3.3e-06 26.2 0.5 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KND90248.1 - 2e-06 27.8 3.7 7.4e-06 25.9 2.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND90248.1 - 0.0014 18.3 3.4 0.0093 15.6 2.3 2.2 1 1 0 1 1 1 1 KR domain GN3L_Grn1 PF08701.6 KND90250.1 - 9.1e-25 86.3 14.3 1.6e-24 85.5 9.9 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KND90250.1 - 1.9e-21 76.1 0.1 4.1e-15 55.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND90250.1 - 8.1e-08 31.9 0.0 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KND90250.1 - 1.8e-07 31.1 3.9 0.027 14.3 0.1 3.6 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 KND90250.1 - 3.7e-05 22.9 0.3 6.5e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KND90250.1 - 0.00056 19.2 0.3 0.023 13.9 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KND90250.1 - 0.0013 19.1 0.9 0.75 10.3 0.1 2.8 2 1 1 3 3 3 2 Miro-like protein ArgK PF03308.11 KND90250.1 - 0.047 12.4 0.1 0.047 12.4 0.1 1.7 2 0 0 2 2 2 0 ArgK protein AIG1 PF04548.11 KND90250.1 - 0.047 12.7 0.2 0.25 10.4 0.1 2.1 2 0 0 2 2 2 0 AIG1 family ORC3_N PF07034.6 KND90250.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_16 PF13191.1 KND90250.1 - 0.32 10.9 2.5 0.67 9.9 0.2 2.5 2 1 0 2 2 2 0 AAA ATPase domain PGA2 PF07543.7 KND90250.1 - 2.4 7.9 16.8 0.029 14.1 5.9 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 CRT10 PF08728.5 KND90250.1 - 3.3 5.5 4.1 4.5 5.1 2.8 1.1 1 0 0 1 1 1 0 CRT10 RNB PF00773.14 KND90251.1 - 2.9e-96 322.5 0.1 4.8e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KND90251.1 - 4.1e-07 30.1 0.2 2.1e-06 27.8 0.0 2.4 2 1 0 2 2 2 1 PIN domain DUF1075 PF06388.6 KND90252.1 - 0.043 13.4 0.9 0.17 11.5 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Tim54 PF11711.3 KND90253.1 - 8.5e-119 396.5 1.6 1e-118 396.3 1.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 zf-met PF12874.2 KND90255.1 - 7.6e-06 25.9 1.0 1.4e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KND90255.1 - 0.00054 19.5 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 KND90255.1 - 0.057 12.6 0.9 0.094 12.0 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Aminotran_3 PF00202.16 KND90256.1 - 1.4e-46 158.9 0.1 2.1e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 KND90256.1 - 0.0058 15.7 0.1 0.0096 14.9 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KND90256.1 - 0.019 14.1 0.1 0.036 13.2 0.1 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 KND90256.1 - 0.081 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V zf-C2H2_jaz PF12171.3 KND90257.1 - 5.8e-08 32.6 9.3 0.00015 21.8 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND90257.1 - 6.7e-07 29.3 7.2 3.5e-05 23.8 1.9 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KND90257.1 - 4.2e-05 23.6 23.5 0.00056 20.1 1.3 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND90257.1 - 0.0013 18.8 0.2 0.0013 18.8 0.2 4.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KND90257.1 - 0.012 15.4 9.5 0.17 11.7 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KND90257.1 - 0.062 13.4 22.4 0.063 13.4 0.3 3.8 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KND90257.1 - 1.5 9.2 14.7 2.7 8.4 0.4 4.0 4 0 0 4 4 4 0 Zinc-finger double domain CBFD_NFYB_HMF PF00808.18 KND90258.1 - 4e-10 39.6 0.0 7.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND90258.1 - 2.8e-05 24.1 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DNA_mis_repair PF01119.14 KND90259.1 - 8.5e-12 44.5 0.0 1.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KND90260.1 - 3.1e-16 59.2 0.1 4.1e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KND90260.1 - 3.8e-12 45.9 0.1 4.9e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pox_RNA_Pol_19 PF05320.7 KND90260.1 - 0.057 13.1 0.1 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TRP PF06011.7 KND90261.1 - 2.1e-88 296.8 23.8 6.9e-88 295.1 16.5 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND90261.1 - 5.3e-23 81.6 0.1 8.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 ML-like domain MscS_porin PF12795.2 KND90263.1 - 5.9e-06 25.7 11.5 6.3e-06 25.6 5.8 2.2 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Yippee-Mis18 PF03226.9 KND90263.1 - 6.2e-05 22.9 4.5 0.00014 21.8 3.1 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly EzrA PF06160.7 KND90263.1 - 6.4e-05 21.3 1.1 6.4e-05 21.3 0.8 2.3 1 1 0 2 2 2 1 Septation ring formation regulator, EzrA WEMBL PF05701.6 KND90263.1 - 0.00057 18.4 4.0 0.00057 18.4 2.8 2.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Filament PF00038.16 KND90263.1 - 0.00079 18.9 11.9 0.00088 18.8 1.9 2.6 1 1 1 2 2 2 1 Intermediate filament protein Spc7 PF08317.6 KND90263.1 - 0.0026 16.4 9.0 0.14 10.7 5.2 2.5 1 1 0 2 2 2 1 Spc7 kinetochore protein Fib_alpha PF08702.5 KND90263.1 - 0.003 17.6 6.0 0.59 10.2 0.6 3.5 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family Fez1 PF06818.10 KND90263.1 - 0.0033 17.4 13.5 0.0058 16.6 6.9 2.5 2 1 1 3 3 2 1 Fez1 SlyX PF04102.7 KND90263.1 - 0.0046 17.2 15.8 0.12 12.7 2.6 4.3 4 0 0 4 4 4 1 SlyX FliJ PF02050.11 KND90263.1 - 0.0064 16.5 14.7 0.0065 16.5 4.0 3.6 1 1 3 4 4 4 1 Flagellar FliJ protein Myosin_tail_1 PF01576.14 KND90263.1 - 0.011 13.4 10.6 0.019 12.7 7.0 1.5 1 1 0 1 1 1 0 Myosin tail IncA PF04156.9 KND90263.1 - 0.012 15.2 16.3 0.86 9.1 7.5 3.0 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 KND90263.1 - 0.025 13.7 6.3 1.6 7.7 0.8 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KND90263.1 - 0.036 13.8 2.0 3.7 7.3 0.0 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.1 KND90263.1 - 0.042 13.2 7.7 0.044 13.2 3.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF3584 PF12128.3 KND90263.1 - 0.044 11.1 13.8 0.04 11.2 8.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.6 KND90263.1 - 0.048 13.5 4.3 3.7 7.5 0.0 4.5 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 KND90263.1 - 0.051 13.3 5.2 4.3 7.1 0.1 3.8 3 1 2 5 5 5 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 KND90263.1 - 0.053 13.2 9.9 0.12 12.1 1.9 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 KND90263.1 - 0.053 13.2 14.0 1.5 8.5 1.4 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KND90263.1 - 0.057 13.3 11.9 0.62 9.9 4.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 KND90263.1 - 0.064 12.7 6.0 0.7 9.4 1.3 3.1 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) M_domain PF12938.2 KND90263.1 - 0.075 12.8 3.3 0.057 13.2 0.5 2.2 2 1 0 2 2 1 0 M domain of GW182 DUF3573 PF12097.3 KND90263.1 - 0.095 11.3 5.3 0.13 10.8 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) DUF972 PF06156.8 KND90263.1 - 0.1 12.9 9.5 1.1 9.6 1.1 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 KND90263.1 - 0.16 12.2 5.5 0.43 10.9 0.8 3.1 2 1 1 3 3 2 0 Snapin/Pallidin Spectrin PF00435.16 KND90263.1 - 0.2 11.9 6.8 1 9.6 0.0 3.5 2 1 1 3 3 3 0 Spectrin repeat AAA_13 PF13166.1 KND90263.1 - 0.21 10.0 6.1 1.3 7.4 3.0 2.0 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.7 KND90263.1 - 0.22 11.3 9.7 5.2 6.8 2.6 3.1 2 1 1 3 3 3 0 Laminin Domain II CENP-F_leu_zip PF10473.4 KND90263.1 - 0.25 11.1 11.7 1.1 9.0 0.5 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KND90263.1 - 0.29 10.1 9.4 0.49 9.3 5.7 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF948 PF06103.6 KND90263.1 - 0.31 10.9 1.2 12 5.8 0.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rab5-bind PF09311.6 KND90263.1 - 0.33 10.8 16.0 1.2 8.9 3.3 2.8 2 1 1 3 3 2 0 Rabaptin-like protein GAS PF13851.1 KND90263.1 - 0.34 10.0 8.6 0.69 9.0 4.0 2.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.1 KND90263.1 - 0.36 10.9 3.9 5.7 7.1 0.1 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Ribosomal_L29 PF00831.18 KND90263.1 - 0.38 10.4 9.5 2.1 8.1 0.2 3.0 3 0 0 3 3 2 0 Ribosomal L29 protein DUF1664 PF07889.7 KND90263.1 - 0.73 9.6 5.1 19 5.0 0.6 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 KND90263.1 - 1.2 8.7 10.9 2.1 7.9 2.8 2.8 1 1 2 3 3 3 0 Mnd1 family NPV_P10 PF05531.7 KND90263.1 - 1.3 9.3 4.9 7.6 6.8 0.2 3.4 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 KND90263.1 - 1.3 8.8 8.5 3.7 7.4 0.4 3.2 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.6 KND90263.1 - 1.6 8.0 5.3 6 6.1 0.2 2.9 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CCDC155 PF14662.1 KND90263.1 - 1.7 8.2 11.2 2.9 7.4 7.0 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Prefoldin PF02996.12 KND90263.1 - 1.8 8.1 7.0 19 4.8 0.0 3.7 4 0 0 4 4 4 0 Prefoldin subunit DUF2730 PF10805.3 KND90263.1 - 1.9 8.2 5.6 40 3.9 0.1 3.9 2 2 1 4 4 4 0 Protein of unknown function (DUF2730) PspA_IM30 PF04012.7 KND90263.1 - 2.2 7.5 18.5 2.3 7.5 4.0 3.2 1 1 1 2 2 2 0 PspA/IM30 family DUF1319 PF07028.6 KND90263.1 - 2.3 8.3 9.0 5.6 7.1 0.3 3.7 2 1 2 4 4 3 0 Protein of unknown function (DUF1319) YlqD PF11068.3 KND90263.1 - 2.4 8.2 14.2 3.5 7.6 1.1 3.3 1 1 1 3 3 3 0 YlqD protein Syntaxin PF00804.20 KND90263.1 - 2.6 8.2 10.9 2.8e+02 1.7 0.0 3.5 1 1 1 2 2 2 0 Syntaxin FUSC PF04632.7 KND90263.1 - 3.9 5.7 9.0 5.3 5.3 6.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.13 KND90263.1 - 4.1 6.3 5.4 1.4 7.8 0.8 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 KND90263.1 - 7.6 6.0 14.1 5.3 6.5 1.2 4.4 3 1 2 5 5 5 0 Septum formation initiator RNase_T PF00929.19 KND90264.1 - 2e-25 89.9 0.0 3.1e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Nt_Gln_amidase PF09764.4 KND90265.1 - 0.044 13.0 0.0 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 N-terminal glutamine amidase SET PF00856.23 KND90266.1 - 2.5e-09 37.6 0.0 1.1e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 KND90266.1 - 2.4e-07 30.5 13.4 2.4e-07 30.5 9.3 2.4 3 0 0 3 3 3 1 MYND finger Herpes_gE PF02480.11 KND90267.1 - 0.058 11.6 0.6 0.076 11.2 0.4 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3446 PF11928.3 KND90267.1 - 9 6.5 10.7 9.9 6.4 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Glutaredoxin PF00462.19 KND90268.1 - 8e-13 48.1 0.0 2.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 KND90268.1 - 0.0021 18.2 0.0 0.0081 16.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LIP PF03583.9 KND90268.1 - 0.052 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Epimerase PF01370.16 KND90269.1 - 2.2e-18 66.5 0.0 3.1e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KND90269.1 - 4.7e-09 35.5 0.0 7.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KND90269.1 - 2.6e-07 30.6 0.0 5.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KND90269.1 - 0.0014 18.6 0.2 0.01 15.8 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND90269.1 - 0.0077 14.9 0.0 0.046 12.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND90269.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein KR PF08659.5 KND90269.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 KND90269.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 KND90269.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CBS PF00571.23 KND90270.1 - 0.029 14.1 0.1 2.3 8.1 0.0 2.9 1 1 1 2 2 2 0 CBS domain AphA_like PF14557.1 KND90270.1 - 0.045 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Mito_carr PF00153.22 KND90271.1 - 1.8e-51 171.7 7.8 2.5e-19 68.7 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Yos1 PF08571.5 KND90272.1 - 9.7e-27 92.8 0.3 1.2e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 Yos1-like DUF3602 PF12223.3 KND90273.1 - 9.2e-16 58.0 12.6 2.1e-12 47.2 4.8 2.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) ATG22 PF11700.3 KND90274.1 - 3.5e-193 642.4 11.6 2.2e-192 639.7 8.1 1.8 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KND90274.1 - 0.00012 20.9 19.4 0.00012 20.9 13.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily BAH PF01426.13 KND90275.1 - 1.9e-05 24.4 0.1 3.3e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 BAH domain zf-RING-like PF08746.6 KND90275.1 - 0.0011 18.9 0.4 0.0027 17.6 0.3 1.7 1 0 0 1 1 1 1 RING-like domain PHD PF00628.24 KND90275.1 - 0.0022 17.6 2.5 0.0047 16.5 1.7 1.5 1 0 0 1 1 1 1 PHD-finger F_actin_cap_B PF01115.12 KND90276.1 - 4.8e-108 359.9 0.0 5.5e-108 359.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF836 PF05768.9 KND90277.1 - 3.4e-12 46.4 0.0 4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KND90277.1 - 0.0041 17.0 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KND90277.1 - 0.0098 16.0 0.1 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain SURNod19 PF07712.7 KND90277.1 - 0.034 12.5 0.0 0.047 12.1 0.0 1.3 1 0 0 1 1 1 0 Stress up-regulated Nod 19 NADH_4Fe-4S PF10589.4 KND90277.1 - 0.062 12.4 0.7 0.14 11.3 0.5 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region CHORD PF04968.7 KND90278.1 - 3.4e-50 168.1 18.2 2.8e-25 88.3 3.4 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KND90278.1 - 5.3e-15 55.7 0.0 8.5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 CS domain V-ATPase_H_N PF03224.9 KND90279.1 - 1.2e-67 228.2 0.0 1.7e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KND90279.1 - 1.3e-38 131.5 1.5 1.7e-38 131.2 0.0 1.9 3 0 0 3 3 3 1 V-ATPase subunit H DUF3730 PF12530.3 KND90279.1 - 0.0015 18.5 0.1 0.5 10.2 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3730) HEAT_2 PF13646.1 KND90279.1 - 0.0059 16.8 0.2 0.18 12.1 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KND90279.1 - 0.12 12.5 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat GCV_T PF01571.16 KND90280.1 - 1.5e-58 197.6 0.0 2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KND90280.1 - 9e-23 80.1 2.0 2.4e-22 78.7 1.4 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Metallophos PF00149.23 KND90282.1 - 1.6e-09 37.4 0.8 4.8e-09 35.9 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PBP1_TM PF14812.1 KND90282.1 - 0.1 12.9 29.2 0.47 10.7 2.1 3.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.13 KND90283.1 - 3.8e-10 39.4 6.5 7.1e-10 38.6 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4169 PF13770.1 KND90283.1 - 3.9 7.4 7.5 1.6 8.7 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) GFA PF04828.9 KND90284.1 - 2.5e-12 46.5 0.5 2.3e-05 24.2 0.4 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF1765 PF08578.5 KND90285.1 - 3.2e-42 143.5 6.6 5.4e-42 142.8 4.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) PhoD PF09423.5 KND90286.1 - 1.3e-10 40.4 0.1 1.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Aldedh PF00171.17 KND90287.1 - 4.1e-105 351.7 0.1 5.4e-105 351.3 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Per1 PF04080.8 KND90288.1 - 2.8e-105 351.5 11.2 4e-105 351.0 7.8 1.2 1 0 0 1 1 1 1 Per1-like DUF4516 PF14990.1 KND90288.1 - 2.5 7.7 4.8 0.93 9.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Sec10 PF07393.6 KND90289.1 - 3.1e-219 729.7 4.5 3.6e-219 729.5 3.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Prenyltransf PF01255.14 KND90290.1 - 1.7e-10 40.4 0.0 8.8e-10 38.0 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase RNB PF00773.14 KND90291.1 - 9.2e-51 173.0 0.0 1.3e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 RNB domain PHP_C PF13263.1 KND90292.1 - 0.087 12.3 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 PHP-associated DUF2360 PF10152.4 KND90292.1 - 0.55 10.5 13.6 0.041 14.1 2.7 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Met_10 PF02475.11 KND90293.1 - 6.7e-69 231.5 0.0 8.4e-69 231.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.5 KND90294.1 - 6.4e-11 41.6 3.6 1.3e-10 40.6 2.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zf-HIT PF04438.11 KND90295.1 - 8.6e-10 38.0 5.2 1.4e-09 37.3 3.6 1.4 1 0 0 1 1 1 1 HIT zinc finger Ebola_NP PF05505.7 KND90295.1 - 0.067 11.2 1.6 0.086 10.8 1.1 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein LPP PF04728.8 KND90296.1 - 0.01 15.6 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper WD40 PF00400.27 KND90297.1 - 7.3e-08 31.9 0.1 7.5e-07 28.7 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2415 PF10313.4 KND90297.1 - 0.017 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) tRNA-synt_2b PF00587.20 KND90298.1 - 2.3e-41 141.2 0.2 4e-41 140.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND90298.1 - 8.6e-18 64.0 0.0 1.9e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KND90298.1 - 2e-11 43.5 0.0 4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KND90298.1 - 4.6e-10 39.1 0.0 1.3e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 TGS domain HSP70 PF00012.15 KND90299.1 - 0.0042 15.0 0.1 0.0046 14.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.15 KND90300.1 - 1.7e-147 491.9 1.8 1.7e-147 491.9 1.2 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KND90300.1 - 4.5e-11 41.9 1.5 5.1e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KND90300.1 - 0.012 15.4 0.1 0.11 12.3 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA Trans_reg_C PF00486.23 KND90300.1 - 0.091 12.6 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal V_ATPase_I PF01496.14 KND90300.1 - 7 4.3 10.4 10 3.8 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GTP_EFTU PF00009.22 KND90301.1 - 1.7e-31 109.0 0.1 1.7e-31 109.0 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KND90301.1 - 2.5e-17 62.7 0.0 6.2e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KND90301.1 - 3.2e-11 43.1 3.2 2.6e-08 33.8 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND90301.1 - 5.4e-06 26.3 0.1 2.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND90301.1 - 0.00058 19.4 0.2 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KND90301.1 - 0.0012 19.3 0.0 0.0055 17.1 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KND90301.1 - 0.022 14.9 0.1 0.27 11.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.13 KND90302.1 - 3.7e-23 82.1 0.0 4.9e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps52 PF04129.7 KND90303.1 - 1.2e-116 390.2 0.1 1.5e-116 389.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KND90303.1 - 1.4e-05 23.5 2.3 2e-05 22.9 1.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 KND90303.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Mer2 DUF1664 PF07889.7 KND90303.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) eIF-5a PF01287.15 KND90304.1 - 1.3e-25 89.0 1.2 1.9e-25 88.5 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KND90304.1 - 0.00079 19.0 0.5 0.00079 19.0 0.4 1.7 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 KND90304.1 - 0.034 14.0 0.3 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.19 KND90304.1 - 0.086 12.8 0.1 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Response regulator receiver domain RRN7 PF11781.3 KND90305.1 - 5.6e-09 35.3 0.8 9.5e-09 34.6 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 DUF35_N PF12172.3 KND90305.1 - 0.12 12.3 1.5 0.31 10.9 1.0 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MIF4G PF02854.14 KND90306.1 - 3.2e-60 203.1 0.0 1.9e-29 102.5 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KND90306.1 - 9e-53 178.5 16.1 9e-53 178.5 11.2 1.9 2 0 0 2 2 2 1 Up-frameshift suppressor 2 OB_NTP_bind PF07717.11 KND90308.1 - 1.2e-16 60.5 0.0 2.5e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KND90308.1 - 6.1e-16 58.2 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND90308.1 - 1.3e-12 47.3 0.0 3.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND90308.1 - 1.7e-06 27.6 0.0 3.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND90308.1 - 2.6e-05 24.3 0.0 7.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND90308.1 - 0.00096 19.1 0.2 0.036 14.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KND90308.1 - 0.0089 15.5 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KND90308.1 - 0.026 14.7 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KND90308.1 - 0.23 11.7 0.1 0.8 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Methyltransf_16 PF10294.4 KND90309.1 - 0.15 11.4 0.0 0.51 9.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase ING PF12998.2 KND90310.1 - 6.1e-22 77.8 3.6 8.9e-22 77.3 2.5 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KND90310.1 - 1.6e-08 34.0 9.7 3.1e-08 33.1 6.7 1.5 1 0 0 1 1 1 1 PHD-finger Axin_b-cat_bind PF08833.5 KND90310.1 - 0.068 12.8 0.8 15 5.3 0.0 3.7 3 0 0 3 3 3 0 Axin beta-catenin binding domain DUF2552 PF10827.3 KND90310.1 - 0.073 13.0 0.4 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) GTP_EFTU PF00009.22 KND90311.1 - 4.9e-09 35.8 0.0 7.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KND90311.1 - 5.6 6.5 5.9 0.83 9.2 0.9 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain URO-D PF01208.12 KND90312.1 - 8.2e-120 399.8 0.0 9.4e-120 399.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Glyco_trans_1_4 PF13692.1 KND90312.1 - 0.1 12.7 0.1 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferases group 1 SNARE PF05739.14 KND90313.1 - 2.8e-06 26.8 5.1 2.8e-06 26.8 3.6 2.1 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 KND90313.1 - 0.59 10.2 6.7 0.21 11.7 2.1 2.1 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Velvet PF11754.3 KND90315.1 - 4.7e-71 238.5 0.3 1.9e-70 236.5 0.0 1.9 2 0 0 2 2 2 1 Velvet factor HisG PF01634.13 KND90316.1 - 3e-46 156.9 0.0 5.8e-46 156.0 0.0 1.5 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KND90316.1 - 3.5e-27 94.1 0.1 6.4e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain HisG PF01634.13 KND90317.1 - 2.9e-46 157.0 0.0 5.7e-46 156.0 0.0 1.5 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KND90317.1 - 3.4e-27 94.1 0.1 6.3e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Ceramidase PF05875.7 KND90318.1 - 3.1e-93 311.7 12.4 3.8e-93 311.4 8.6 1.1 1 0 0 1 1 1 1 Ceramidase DUF3479 PF11965.3 KND90318.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) F-box-like PF12937.2 KND90319.1 - 8.9e-05 22.1 0.1 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND90319.1 - 0.019 14.6 0.2 0.058 13.0 0.1 1.8 1 1 0 1 1 1 0 F-box domain DNA_pol_B PF00136.16 KND90320.1 - 2.4e-92 310.1 0.0 4.4e-92 309.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KND90320.1 - 4.2e-22 78.4 0.1 2e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KND90320.1 - 1.1e-18 67.0 2.5 3.5e-18 65.3 1.7 2.0 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Slx4 PF09494.5 KND90320.1 - 0.068 12.9 0.1 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 Slx4 endonuclease Slu7 PF11708.3 KND90321.1 - 3.6e-72 242.9 12.9 3.6e-72 242.9 9.0 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KND90321.1 - 0.006 16.2 0.7 0.012 15.2 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KND90321.1 - 0.048 13.6 1.0 0.092 12.7 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Dor1 PF04124.7 KND90322.1 - 1.1e-47 162.1 0.1 1.5e-39 135.4 0.0 2.5 1 1 2 3 3 3 3 Dor1-like family WVELL PF14043.1 KND90322.1 - 0.17 11.5 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 WVELL protein Mito_carr PF00153.22 KND90323.1 - 3e-53 177.5 0.5 9.2e-18 63.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S4 PF00163.14 KND90326.1 - 2.2e-28 98.4 0.7 4.6e-28 97.4 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KND90326.1 - 4.3e-13 48.4 1.2 4.3e-13 48.4 0.8 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 KND90327.1 - 9.4e-38 128.0 5.2 1.6e-37 127.2 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF3865 PF12981.2 KND90327.1 - 0.0088 15.8 0.1 0.0099 15.6 0.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3865) BatD PF13584.1 KND90327.1 - 0.01 14.4 0.1 0.011 14.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Fungal_trans PF04082.13 KND90328.1 - 1.3e-17 63.5 1.8 3.3e-17 62.2 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.2 KND90328.1 - 0.0033 17.1 0.0 0.0086 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND90328.1 - 0.018 14.7 1.3 0.051 13.2 0.0 2.5 2 0 0 2 2 2 0 F-box domain HSBP1 PF06825.7 KND90328.1 - 0.18 11.4 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF4350 PF14258.1 KND90329.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) MULE PF10551.4 KND90330.1 - 1.3e-09 38.0 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 KND90330.1 - 5.6e-06 25.1 0.0 1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Herpes_gE PF02480.11 KND90330.1 - 0.16 10.2 0.2 0.26 9.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F-box PF00646.28 KND90332.1 - 2.6e-08 33.2 0.3 6.4e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KND90332.1 - 2.5e-06 27.1 2.8 4.6e-06 26.2 0.1 2.5 2 0 0 2 2 2 1 F-box-like Mod_r PF07200.8 KND90334.1 - 2.3e-08 34.1 1.0 5.6e-08 32.8 0.7 1.6 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rad60-SLD PF11976.3 KND90335.1 - 1.6e-20 72.5 0.1 1.9e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KND90335.1 - 3.7e-07 29.4 0.0 4.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 KND90335.1 - 0.029 13.9 0.0 0.031 13.8 0.0 1.0 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain SRP9-21 PF05486.7 KND90335.1 - 0.11 12.2 0.1 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 KND90336.1 - 2.5e-63 213.8 0.0 3.6e-39 134.0 0.0 2.6 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF4356 PF14266.1 KND90336.1 - 0.13 10.5 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) Ric8 PF10165.4 KND90337.1 - 1.2e-22 80.3 0.7 6e-18 64.8 0.1 2.5 2 1 0 2 2 2 2 Guanine nucleotide exchange factor synembryn LIM PF00412.17 KND90338.1 - 6.6e-25 86.9 23.1 2.9e-08 33.6 4.7 3.7 3 0 0 3 3 3 3 LIM domain CHCH PF06747.8 KND90338.1 - 0.001 18.8 1.0 0.0022 17.8 0.7 1.6 1 0 0 1 1 1 1 CHCH domain DUF2321 PF10083.4 KND90338.1 - 1.3 8.4 6.1 0.19 11.2 0.4 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF1903 PF08991.5 KND90340.1 - 3.8e-18 65.3 3.3 3.8e-18 65.3 2.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) NDUFB10 PF10249.4 KND90340.1 - 0.024 14.7 0.3 0.028 14.5 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 CHCH PF06747.8 KND90340.1 - 0.04 13.8 2.6 0.04 13.8 1.8 1.6 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 KND90340.1 - 0.044 13.5 2.5 0.07 12.9 1.7 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_1 PF00170.16 KND90341.1 - 0.00021 21.1 6.0 0.00045 20.1 4.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 KND90341.1 - 0.022 14.4 3.3 12 5.4 0.0 2.3 2 1 0 2 2 2 0 Transcription factor PAP1 DUF904 PF06005.7 KND90341.1 - 0.53 10.6 5.7 0.1 12.8 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KND90341.1 - 6.6 6.6 10.0 43 4.0 6.5 2.1 1 1 0 1 1 1 0 Basic region leucine zipper API5 PF05918.6 KND90342.1 - 1.5 7.2 4.5 1.9 6.8 3.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Prefoldin PF02996.12 KND90343.1 - 3.3e-23 81.5 0.3 4.5e-23 81.1 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.6 KND90343.1 - 0.00078 19.2 7.4 0.2 11.5 0.1 2.3 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.15 KND90343.1 - 0.0032 17.1 4.1 0.075 12.7 0.5 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 KND90343.1 - 0.013 15.4 1.5 0.048 13.6 0.2 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.6 KND90343.1 - 0.041 12.5 1.7 0.079 11.6 1.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 KND90343.1 - 0.14 11.3 3.3 4.5 6.4 0.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HSCB_C PF07743.8 KND90343.1 - 0.62 10.5 3.8 0.78 10.2 0.1 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain AAA PF00004.24 KND90345.1 - 5.3e-16 59.0 0.0 1.6e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND90345.1 - 2.7e-11 43.8 0.0 7.6e-10 39.0 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 KND90345.1 - 1.4e-09 37.7 0.0 3.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 KND90345.1 - 2e-07 31.1 0.0 5.9e-07 29.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KND90345.1 - 0.0002 21.0 0.1 0.00063 19.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KND90345.1 - 0.00073 19.3 0.0 0.014 15.1 0.0 2.3 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KND90345.1 - 0.0038 16.9 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KND90345.1 - 0.0049 17.6 0.0 0.026 15.3 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_11 PF13086.1 KND90345.1 - 0.0056 16.2 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KND90345.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KND90345.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KND90345.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 KND90345.1 - 0.021 13.7 0.0 0.28 10.1 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 KND90345.1 - 0.03 13.7 0.0 1.5 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KND90345.1 - 0.038 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_32 PF13654.1 KND90345.1 - 0.053 12.1 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KND90345.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND90345.1 - 0.12 12.0 0.1 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 KND90345.1 - 0.22 10.4 0.0 0.45 9.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.27 KND90346.1 - 2.5e-45 150.7 15.2 5.6e-09 35.5 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KND90346.1 - 0.00053 18.2 3.6 3 5.8 0.1 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Ank_2 PF12796.2 KND90347.1 - 3.2e-26 91.4 0.0 3.7e-17 62.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND90347.1 - 1.1e-25 88.1 0.1 7.2e-07 28.7 0.0 4.5 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KND90347.1 - 4.5e-25 87.0 0.2 5.4e-10 39.1 0.2 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND90347.1 - 1.2e-20 71.5 0.0 0.00019 21.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KND90347.1 - 1.3e-18 67.0 0.5 5.3e-07 29.9 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) TMF_TATA_bd PF12325.3 KND90348.1 - 3e-38 130.2 9.2 3e-38 130.2 6.3 6.0 3 2 2 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KND90348.1 - 3.8e-20 71.4 13.2 3.8e-20 71.4 9.1 8.7 5 3 4 9 9 9 1 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 KND90348.1 - 5.8 6.8 21.9 2.7 7.9 1.7 5.7 4 2 3 7 7 7 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KND90348.1 - 8.9 5.3 21.1 1.1 8.3 1.6 4.3 2 1 3 5 5 5 0 Reovirus sigma C capsid protein MMS1_N PF10433.4 KND90349.1 - 1.2e-88 297.4 0.0 1.6e-87 293.7 0.0 2.0 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KND90349.1 - 0.015 14.4 0.0 0.045 12.8 0.0 1.7 2 1 0 2 2 2 0 CPSF A subunit region ESPR PF13018.1 KND90349.1 - 0.088 12.4 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system SSP160 PF06933.6 KND90350.1 - 0.15 9.9 1.1 0.24 9.3 0.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GST_C_2 PF13410.1 KND90352.1 - 8.3e-05 22.3 1.0 0.00014 21.7 0.7 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND90352.1 - 0.091 13.2 0.1 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C2H2_4 PF13894.1 KND90353.1 - 2.5e-06 27.4 7.3 0.00031 20.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KND90353.1 - 5.2e-05 23.3 9.2 0.0034 17.6 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND90353.1 - 0.0028 17.8 1.5 0.0028 17.8 1.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 KND90353.1 - 0.021 15.0 5.6 0.41 10.9 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KND90353.1 - 0.43 11.0 4.1 0.78 10.1 0.3 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger Prp31_C PF09785.4 KND90354.1 - 3.2e-42 143.8 0.7 7e-42 142.7 0.5 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KND90354.1 - 8.7e-39 132.2 0.1 1.6e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KND90354.1 - 1.7e-19 69.3 0.0 3.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain TPR_14 PF13428.1 KND90355.1 - 5e-22 76.3 16.2 0.014 16.0 0.0 10.5 7 3 6 13 13 12 6 Tetratricopeptide repeat HAT PF02184.11 KND90355.1 - 1e-21 76.3 56.5 5.8e-13 48.3 0.7 11.4 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 KND90355.1 - 1.2e-17 64.0 0.0 9.2e-05 22.7 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND90355.1 - 9e-16 58.0 16.5 0.00052 20.6 0.0 7.5 7 1 1 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND90355.1 - 1.3e-05 25.0 18.8 0.024 14.5 0.0 7.8 8 2 2 10 10 9 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KND90355.1 - 2.1e-05 24.1 22.0 0.41 10.4 0.7 6.9 4 2 1 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_15 PF13429.1 KND90355.1 - 2.4e-05 23.5 18.6 0.25 10.3 0.2 5.1 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 KND90355.1 - 0.00013 21.4 4.6 3.9 7.1 0.0 6.3 5 2 1 7 7 7 1 TPR repeat TPR_2 PF07719.12 KND90355.1 - 0.0014 18.3 16.8 2.2 8.3 0.0 7.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND90355.1 - 0.0048 16.9 0.4 6.3 7.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KND90355.1 - 0.0075 16.6 15.4 62 4.3 0.3 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND90355.1 - 0.0081 15.9 4.3 9.4 6.1 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND90355.1 - 0.21 11.2 4.3 53 3.6 0.4 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KND90355.1 - 0.33 9.8 28.8 1.1 8.1 1.2 7.0 3 2 3 6 6 6 0 NRDE-2, necessary for RNA interference Fis1_TPR_C PF14853.1 KND90355.1 - 0.59 10.0 10.2 7 6.6 0.2 5.9 9 0 0 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat Fungal_trans PF04082.13 KND90356.1 - 2.6e-20 72.3 0.1 5.9e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90356.1 - 9.9e-09 34.9 9.9 9.9e-09 34.9 6.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetate_kinase PF00871.12 KND90359.1 - 4.8e-88 295.3 0.0 6.7e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.19 KND90359.1 - 2.2e-31 108.9 28.9 1e-19 70.4 5.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KND90359.1 - 1e-21 77.0 22.9 3.5e-15 55.5 8.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.5 KND90359.1 - 0.13 11.9 7.2 0.87 9.2 2.4 2.8 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Glutaredoxin PF00462.19 KND90360.1 - 3.3e-17 62.2 0.0 1.7e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KND90360.1 - 8e-13 47.9 0.0 1.8e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KND90360.1 - 0.0023 18.0 0.0 1.3 9.1 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like ArsC PF03960.10 KND90360.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 ArsC family Npa1 PF11707.3 KND90361.1 - 1.7e-63 214.6 0.0 3.5e-63 213.6 0.0 1.6 1 1 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Chitin_synth_2 PF03142.10 KND90362.1 - 2.2e-255 848.0 1.1 3e-255 847.6 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KND90362.1 - 7.8e-170 566.2 0.0 9.9e-170 565.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KND90362.1 - 7e-16 57.7 0.2 9.8e-15 54.0 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KND90362.1 - 2.8e-15 55.8 0.1 5.8e-10 38.8 0.0 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KND90362.1 - 4.3e-15 55.9 4.9 4.3e-15 55.9 3.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND90362.1 - 6.9e-15 55.4 0.1 1.7e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KND90362.1 - 5.6e-05 22.8 0.0 0.0077 15.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 MMR_HSR1 PF01926.18 KND90362.1 - 0.00031 20.6 0.1 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KND90362.1 - 0.00067 19.6 0.2 0.0026 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KND90362.1 - 0.0069 15.8 0.1 0.023 14.1 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4164 PF13747.1 KND90362.1 - 0.0087 16.1 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) AAA_22 PF13401.1 KND90362.1 - 0.01 15.9 0.1 0.046 13.8 0.1 2.1 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KND90362.1 - 0.013 14.6 0.1 0.037 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Glyco_transf_21 PF13506.1 KND90362.1 - 0.028 13.7 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 RNA_helicase PF00910.17 KND90362.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KND90362.1 - 0.054 13.7 0.5 0.16 12.2 0.1 1.9 2 0 0 2 2 1 0 ABC transporter Dynamin_N PF00350.18 KND90362.1 - 0.1 12.4 1.6 3.9 7.2 0.2 2.7 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.1 KND90362.1 - 0.19 11.9 0.1 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2592 PF10766.4 KND90362.1 - 0.59 9.5 3.6 1.6 8.1 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) His_Phos_2 PF00328.17 KND90363.1 - 2.8e-56 191.3 0.0 3.2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Inhibitor_I9 PF05922.11 KND90365.1 - 1.1e-12 48.3 0.0 1.1e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 SelP_N PF04592.9 KND90365.1 - 0.51 9.6 10.0 0.76 9.1 6.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region p450 PF00067.17 KND90366.1 - 2.4e-50 171.3 0.0 6.9e-50 169.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Atrophin-1 PF03154.10 KND90366.1 - 0.19 9.8 0.5 0.25 9.4 0.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Chitin_synth_2 PF03142.10 KND90367.1 - 2.1e-229 762.3 0.1 2.8e-229 761.9 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KND90367.1 - 2.9e-54 184.3 0.0 1.2e-43 149.1 0.0 2.8 2 1 0 2 2 2 2 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 KND90367.1 - 1.5e-17 63.9 1.8 1.5e-17 63.9 1.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND90367.1 - 3.6e-15 56.4 0.0 2.1e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KND90367.1 - 5.9e-14 51.6 1.4 2.3e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 KND90367.1 - 6.9e-14 51.3 2.8 3.5e-13 49.1 2.3 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 KND90367.1 - 5.5e-06 25.7 0.2 3.1e-05 23.3 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KND90367.1 - 0.0011 18.7 0.0 0.064 12.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.4 KND90368.1 - 1.2e-41 141.9 0.0 1.5e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KND90368.1 - 5.7e-16 58.2 0.0 6.1e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KND90368.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pkinase PF00069.20 KND90369.1 - 1.9e-65 220.5 0.0 2.5e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90369.1 - 5.5e-41 140.3 0.0 7.4e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND90369.1 - 1.8e-07 30.4 0.0 4.3e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND90369.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND90369.1 - 0.0094 15.3 0.0 0.031 13.6 0.0 1.8 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 KND90369.1 - 0.043 13.1 0.2 0.082 12.2 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KND90369.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KND90369.1 - 0.09 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Yip1 PF04893.12 KND90370.1 - 7.2e-12 45.1 17.4 1.2e-11 44.4 12.1 1.4 1 1 0 1 1 1 1 Yip1 domain Nuc_sug_transp PF04142.10 KND90370.1 - 0.26 10.3 4.8 2.1 7.4 3.3 2.1 1 1 0 1 1 1 0 Nucleotide-sugar transporter MENTAL PF10457.4 KND90370.1 - 5.7 6.5 7.7 0.37 10.3 1.9 1.5 2 0 0 2 2 2 0 Cholesterol-capturing domain G6PD_C PF02781.11 KND90371.1 - 4.3e-134 445.9 0.0 5.7e-134 445.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KND90371.1 - 1.5e-63 214.3 0.0 2.5e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IDO PF01231.13 KND90371.1 - 0.17 10.3 0.1 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Pkinase PF00069.20 KND90372.1 - 1.8e-09 37.1 0.0 4.5e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90372.1 - 5.7e-07 28.8 0.0 9.6e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND90372.1 - 9.8e-07 28.7 0.3 0.00014 21.6 0.3 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KND90372.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like La PF05383.12 KND90373.1 - 4.2e-11 42.4 0.0 6.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KND90373.1 - 1.2e-07 31.2 0.2 2.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND90373.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND90373.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCSD PF05177.7 KND90373.1 - 1.9 9.0 19.7 0.094 13.2 8.8 2.3 2 0 0 2 2 2 0 RCSD region MFS_1 PF07690.11 KND90374.1 - 2e-38 132.0 26.7 2e-38 132.0 18.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND90374.1 - 7.5e-10 37.9 0.3 7.5e-10 37.9 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KND90374.1 - 0.00048 18.4 1.8 0.00072 17.8 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) tRNA-synt_2 PF00152.15 KND90375.1 - 6.6e-74 248.6 0.0 1e-73 248.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KND90375.1 - 1.6e-13 50.1 0.1 2.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KND90375.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.8 KND90376.1 - 1.2e-41 142.6 0.0 1.8e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KND90376.1 - 3.4e-06 26.0 1.6 1.5e-05 23.8 1.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KND90376.1 - 0.00012 21.4 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KND90376.1 - 0.00031 20.6 0.5 0.00063 19.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KND90376.1 - 0.00088 18.7 0.0 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KND90376.1 - 0.0014 18.3 0.0 0.0044 16.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 KND90377.1 - 0.00061 18.9 0.6 0.18 10.7 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Inositol_P PF00459.20 KND90378.1 - 4.9e-60 203.1 0.0 6.1e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family COX6A PF02046.10 KND90379.1 - 1.1e-39 134.9 1.8 1.3e-39 134.7 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 KND90380.1 - 3.9e-20 71.6 0.0 1.2e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KND90380.1 - 1.6e-15 57.7 0.0 2.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CIA30 PF08547.7 KND90381.1 - 2.3e-41 141.2 0.0 2.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Apc5 PF12862.2 KND90382.1 - 1.4e-32 111.3 5.6 2.4e-32 110.6 1.9 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.1 KND90382.1 - 0.84 9.5 5.9 2.3 8.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND90382.1 - 5 8.0 24.2 1.6 9.5 0.5 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat MAT_Alpha1 PF04769.7 KND90383.1 - 3.2e-50 170.2 0.0 4.4e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 ANTH PF07651.11 KND90384.1 - 2.1e-79 266.1 0.0 2.1e-79 266.1 0.0 2.2 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 KND90384.1 - 1.7e-62 209.8 8.9 1.7e-62 209.8 6.1 4.9 5 1 1 6 6 6 1 I/LWEQ domain ENTH PF01417.15 KND90384.1 - 2e-05 24.4 0.0 8.9e-05 22.3 0.0 2.2 1 0 0 1 1 1 1 ENTH domain NFRKB_winged PF14465.1 KND90384.1 - 0.057 13.2 0.9 1.9 8.4 0.1 3.1 2 0 0 2 2 2 0 NFRKB Winged Helix-like Surfac_D-trimer PF09006.6 KND90384.1 - 7.8 6.3 8.9 0.8 9.4 0.2 3.7 3 1 1 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation HMG_box PF00505.14 KND90385.1 - 7.8e-19 67.7 2.4 1.2e-18 67.1 1.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND90385.1 - 1.2e-06 28.7 1.0 1.8e-06 28.2 0.3 1.5 2 0 0 2 2 2 1 HMG-box domain RRM_1 PF00076.17 KND90387.1 - 8.1e-19 67.0 0.0 7.5e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND90387.1 - 8.5e-14 51.2 0.0 5.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tim44 PF04280.10 KND90388.1 - 1.2e-05 25.2 0.0 3.1e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Tim44-like domain DUF2380 PF09533.5 KND90388.1 - 0.54 9.6 5.4 1.3 8.4 0.3 2.2 1 1 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) Mo-co_dimer PF03404.11 KND90389.1 - 6.8e-55 184.2 0.1 1.6e-54 183.0 0.1 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KND90389.1 - 7.2e-50 168.7 0.0 1.1e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KND90389.1 - 5.4e-30 103.4 0.0 1.1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KND90389.1 - 2.6e-24 85.8 0.0 5.5e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KND90389.1 - 1e-21 76.4 0.0 2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KND90389.1 - 0.011 15.6 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DEAD PF00270.24 KND90390.1 - 4.3e-25 88.1 0.0 8.2e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 KND90390.1 - 1.2e-14 54.6 0.4 4.6e-14 52.7 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 KND90390.1 - 6.3e-09 35.5 0.0 2e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND90390.1 - 2.6e-05 24.1 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.6 KND90390.1 - 0.0068 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like Terminase_GpA PF05876.7 KND90390.1 - 0.02 13.2 0.0 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Ran_BP1 PF00638.13 KND90391.1 - 1.6e-15 57.2 0.5 2.9e-07 30.5 0.1 2.2 2 0 0 2 2 2 2 RanBP1 domain DUF4611 PF15387.1 KND90391.1 - 0.045 13.8 0.4 0.045 13.8 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) eIF3_subunit PF08597.5 KND90392.1 - 1.4e-68 231.0 21.3 1.6e-68 230.9 14.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit KfrA_N PF11740.3 KND90392.1 - 0.73 10.2 27.0 0.18 12.2 15.0 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Spore_coat_CotO PF14153.1 KND90392.1 - 1.1 8.7 15.6 0.044 13.2 5.5 2.0 2 0 0 2 2 2 0 Spore coat protein CotO DUF2413 PF10310.4 KND90392.1 - 3.7 6.2 24.4 0.48 9.1 10.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) YL1 PF05764.8 KND90392.1 - 9.4 5.7 30.5 0.5 9.9 14.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein AOX PF01786.12 KND90393.1 - 2.4e-84 281.8 0.2 3.2e-84 281.4 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Enolase_C PF00113.17 KND90394.1 - 2.1e-153 509.5 0.1 2.7e-153 509.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KND90394.1 - 8.9e-57 190.6 0.5 1.5e-56 189.9 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KND90394.1 - 0.0017 17.3 0.6 0.13 11.1 0.1 2.7 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 KND90394.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like MR_MLE PF01188.16 KND90394.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain KH_1 PF00013.24 KND90395.1 - 0.0001 21.8 1.4 0.00016 21.2 0.4 1.7 2 0 0 2 2 2 1 KH domain AP_endonuc_2 PF01261.19 KND90396.1 - 1.9e-25 89.4 0.3 3.7e-25 88.4 0.2 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 KND90397.1 - 6.6e-42 142.2 0.3 1.1e-41 141.4 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KND90397.1 - 4.2e-13 49.0 0.0 6.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90397.1 - 4.1e-05 22.7 0.1 0.00018 20.6 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PI3K_1B_p101 PF10486.4 KND90397.1 - 0.73 7.3 5.9 1.2 6.5 4.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-H2C2_2 PF13465.1 KND90398.1 - 5.4e-14 51.6 18.4 9e-07 28.8 1.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KND90398.1 - 1.2e-11 44.2 23.0 0.0018 18.4 5.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND90398.1 - 2.6e-08 33.6 20.1 0.0028 17.8 4.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KND90398.1 - 0.00026 20.7 8.3 0.61 10.0 0.0 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND90398.1 - 0.00083 19.4 9.5 0.19 11.9 2.6 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KND90398.1 - 0.035 14.2 12.1 0.2 11.8 4.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding bZIP_1 PF00170.16 KND90398.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor zinc_ribbon_4 PF13717.1 KND90398.1 - 0.23 11.1 5.3 2.3 7.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain FYDLN_acid PF09538.5 KND90398.1 - 0.24 12.0 2.9 6.5 7.3 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_5 PF13719.1 KND90398.1 - 0.25 10.9 5.3 2.2 7.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KND90398.1 - 0.26 11.1 7.9 0.79 9.5 2.4 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.1 KND90398.1 - 0.26 11.0 5.7 0.11 12.1 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C3HC4_3 PF13920.1 KND90398.1 - 0.26 10.9 3.9 8.6 6.1 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KND90398.1 - 0.28 11.0 5.3 1.7 8.5 3.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KND90398.1 - 0.35 10.8 10.0 5.8 6.9 3.0 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-CHCC PF10276.4 KND90398.1 - 0.48 10.3 7.2 2.2 8.1 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain DUF2225 PF09986.4 KND90398.1 - 0.59 9.5 2.0 1.9 7.9 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_3 PF14369.1 KND90398.1 - 0.92 9.5 6.5 17 5.5 0.1 3.1 2 1 1 3 3 3 0 zinc-finger zf-CHY PF05495.7 KND90398.1 - 0.96 9.6 8.5 2.1 8.5 5.9 1.5 1 1 0 1 1 1 0 CHY zinc finger zf-BED PF02892.10 KND90398.1 - 1 9.1 9.1 0.49 10.2 2.4 2.5 2 0 0 2 2 2 0 BED zinc finger zinc-ribbons_6 PF07191.7 KND90398.1 - 1.4 8.7 4.9 3.5 7.4 1.7 2.2 2 0 0 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 KND90398.1 - 3.3 7.0 4.6 7.6 5.9 0.9 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding GAGA PF09237.6 KND90398.1 - 3.6 7.2 6.7 2.3 7.8 0.7 3.0 1 1 2 3 3 3 0 GAGA factor zf-met PF12874.2 KND90398.1 - 7.1 6.9 10.5 11 6.3 1.7 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DAGAT PF03982.8 KND90399.1 - 3.5e-96 321.4 0.0 4.4e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Hist_deacetyl PF00850.14 KND90400.1 - 5.6e-78 262.3 0.0 1.2e-77 261.3 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain SUN PF03856.8 KND90401.1 - 2.9e-86 288.8 10.8 4.2e-86 288.3 7.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 KND90401.1 - 3.6 6.8 12.5 4.5 6.5 8.6 1.1 1 0 0 1 1 1 0 Vta1 like CBF PF03914.12 KND90402.1 - 1.8e-45 154.3 0.2 6.7e-45 152.4 0.1 2.1 1 0 0 1 1 1 1 CBF/Mak21 family HGTP_anticodon PF03129.15 KND90403.1 - 1e-11 44.5 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TRAM_LAG1_CLN8 PF03798.11 KND90404.1 - 4.7e-46 156.8 16.3 4.7e-46 156.8 11.3 1.5 2 0 0 2 2 2 1 TLC domain A_deaminase PF00962.17 KND90405.1 - 1.7e-110 369.0 0.2 2.4e-110 368.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 KND90405.1 - 1.2e-66 224.7 6.6 3.8e-40 137.6 1.4 2.1 1 1 1 2 2 2 2 UAA transporter family SHD1 PF03983.7 KND90405.1 - 8.1e-37 124.7 0.1 1.5e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 KND90405.1 - 3.3e-31 106.4 10.3 1.6e-12 46.6 0.4 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KND90405.1 - 1.4e-26 91.8 10.7 3.3e-13 48.9 0.2 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KND90405.1 - 5.7e-22 76.9 0.2 2.3e-09 36.5 0.0 4.4 4 0 0 4 4 4 2 Variant SH3 domain DUF1720 PF08226.6 KND90405.1 - 0.0011 19.0 20.6 0.0011 19.0 14.3 5.4 2 1 2 5 5 5 1 Domain of unknown function (DUF1720) SH3_3 PF08239.6 KND90405.1 - 0.0074 16.4 3.1 4.9 7.4 0.1 3.7 3 0 0 3 3 3 1 Bacterial SH3 domain HMG_box PF00505.14 KND90406.1 - 1.1e-10 41.5 0.4 2.7e-10 40.3 0.2 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND90406.1 - 0.0026 18.0 0.2 0.0061 16.8 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain PHD PF00628.24 KND90407.1 - 3.8e-08 32.8 7.6 7.6e-08 31.9 5.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KND90407.1 - 0.0069 15.6 5.7 0.015 14.5 4.0 1.5 1 0 0 1 1 1 1 PHD-finger Ion_trans PF00520.26 KND90408.1 - 8.6e-101 335.2 78.6 5.4e-32 110.6 3.6 5.2 5 1 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 KND90408.1 - 0.002 16.5 0.2 0.002 16.5 0.2 7.4 7 1 1 8 8 8 5 Polycystin cation channel WD40 PF00400.27 KND90410.1 - 3.2e-12 45.8 2.4 0.94 9.4 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat MutS_V PF00488.16 KND90412.1 - 2.9e-55 187.2 0.0 4.3e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND90412.1 - 5.1e-20 72.1 0.1 1.1e-19 71.1 0.0 1.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KND90412.1 - 0.0058 16.7 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV YfcL PF08891.6 KND90412.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 YfcL protein AAA_14 PF13173.1 KND90412.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMgT PF10270.4 KND90413.1 - 5.6e-31 107.1 0.0 6.7e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter RIC1 PF07064.8 KND90414.1 - 7.2e-82 274.7 0.1 1e-81 274.2 0.1 1.2 1 0 0 1 1 1 1 RIC1 CK_II_beta PF01214.13 KND90414.1 - 8.6e-71 237.2 0.2 1.4e-70 236.6 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit WD40 PF00400.27 KND90414.1 - 0.014 15.3 0.1 35 4.4 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_L2_C PF03947.13 KND90415.1 - 3.7e-45 152.9 5.4 2.1e-44 150.4 3.8 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KND90415.1 - 4.3e-24 84.2 0.3 8.2e-24 83.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain F-box-like PF12937.2 KND90416.1 - 0.023 14.4 0.0 0.088 12.5 0.0 2.1 1 0 0 1 1 1 0 F-box-like Dynamin_M PF01031.15 KND90417.1 - 2.8e-112 374.3 0.0 5.1e-112 373.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KND90417.1 - 2.7e-55 186.7 0.0 5.1e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KND90417.1 - 7.3e-31 105.9 1.4 1.6e-30 104.8 1.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KND90417.1 - 0.00062 19.7 0.0 0.0019 18.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND90417.1 - 0.025 15.0 0.0 0.065 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 KND90417.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PLA2_B PF01735.13 KND90418.1 - 1.4e-30 105.9 0.0 2.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain APS_kinase PF01583.15 KND90421.1 - 9.9e-72 239.7 0.0 1.4e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KND90421.1 - 1.6e-07 31.2 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND90421.1 - 6.5e-06 26.9 0.0 8.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND90421.1 - 3.1e-05 24.2 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND90421.1 - 5.6e-05 22.4 0.0 6.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KND90421.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KND90421.1 - 0.014 15.3 0.4 0.026 14.5 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KND90421.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 KND90421.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family V-ATPase_C PF03223.10 KND90422.1 - 2.6e-109 365.5 0.0 3.1e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 KND90422.1 - 0.00037 20.7 0.6 0.0028 17.9 0.1 2.2 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain ScpA_ScpB PF02616.9 KND90422.1 - 0.053 13.1 0.1 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 ScpA/B protein AT_hook PF02178.14 KND90423.1 - 0.94 9.3 26.4 0.85 9.5 0.4 4.7 3 0 0 3 3 3 0 AT hook motif MFS_1 PF07690.11 KND90424.1 - 2.6e-28 98.7 28.2 6.5e-28 97.4 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KND90425.1 - 2.2e-66 224.3 0.0 2.5e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KND90426.1 - 4.3e-81 272.4 0.0 6.6e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 KND90426.1 - 4.1e-16 58.6 1.0 6.4e-16 57.9 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding_C PF13193.1 KND90426.1 - 1.1e-07 32.6 0.2 3.3e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KND90427.1 - 5.1e-82 275.4 0.0 6.9e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND90427.1 - 5.4e-10 40.0 0.1 1.6e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NPR3 PF03666.8 KND90428.1 - 2.1e-127 425.3 0.0 2.7e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 KND90428.1 - 0.046 12.4 0.1 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Pkinase PF00069.20 KND90429.1 - 2e-60 204.1 0.0 1.2e-37 129.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND90429.1 - 1.1e-27 96.7 0.0 2.5e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KND90429.1 - 4.6e-14 52.3 0.1 1.2e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.1 KND90429.1 - 8.8e-07 28.1 0.0 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KND90429.1 - 2e-05 24.4 0.0 0.018 14.7 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KND90429.1 - 0.024 13.4 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KND90429.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 KND90429.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain Aminotran_1_2 PF00155.16 KND90430.1 - 6.5e-18 64.8 0.0 8.7e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KND90430.1 - 3.4e-07 29.1 0.0 5.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KND90430.1 - 0.1 11.6 0.0 0.42 9.5 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PAP2 PF01569.16 KND90431.1 - 2.4e-18 66.0 0.8 2.4e-18 66.0 0.5 2.2 2 2 0 2 2 2 1 PAP2 superfamily Mn_catalase PF05067.7 KND90431.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Manganese containing catalase TPPK_C PF12555.3 KND90431.1 - 7.8 6.3 7.8 0.63 9.8 0.8 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Amino_oxidase PF01593.19 KND90432.1 - 2.1e-18 66.6 0.0 2.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND90432.1 - 2.2e-11 43.6 0.0 1.4e-10 41.0 0.0 2.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND90432.1 - 7e-09 35.0 2.8 2.2e-06 26.8 0.2 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND90432.1 - 0.00011 22.5 0.0 0.04 14.3 0.0 3.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND90432.1 - 0.0011 18.7 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND90432.1 - 0.0037 17.3 0.4 0.13 12.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND90432.1 - 0.0096 15.0 0.1 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KND90432.1 - 0.016 13.8 0.1 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KND90432.1 - 0.082 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Med14 PF08638.6 KND90433.1 - 1.2e-68 230.2 0.0 1.9e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 p450 PF00067.17 KND90434.1 - 5.5e-61 206.5 0.0 8.4e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DpnII PF04556.7 KND90434.1 - 0.019 14.0 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 DpnII restriction endonuclease zf-CCCH_2 PF14608.1 KND90435.1 - 3.4e-10 39.5 56.2 1.9e-06 27.6 7.1 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KND90435.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) HLH PF00010.21 KND90436.1 - 6.6e-13 48.1 0.0 1.8e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 KND90437.1 - 4.8e-31 107.3 17.1 6e-31 106.9 11.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KND90437.1 - 0.025 13.5 0.1 0.049 12.5 0.1 1.6 1 1 0 1 1 1 0 Peptidase family M50 La PF05383.12 KND90438.1 - 5.9e-18 64.4 0.1 9.7e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 La domain Sugar_tr PF00083.19 KND90439.1 - 7.7e-21 74.1 28.7 6.4e-20 71.1 19.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3611 PF12263.3 KND90439.1 - 0.0051 16.2 1.2 0.014 14.7 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3611) zf-C2H2_4 PF13894.1 KND90440.1 - 0.29 11.5 0.0 0.29 11.5 0.0 7.5 8 0 0 8 8 8 0 C2H2-type zinc finger Med9 PF07544.8 KND90441.1 - 0.027 14.1 0.1 0.074 12.8 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Choline_kinase PF01633.15 KND90442.1 - 8.5e-49 165.9 0.0 1.8e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KND90442.1 - 1.8e-11 44.2 0.1 3.2e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KND90442.1 - 0.0044 16.2 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KND90442.1 - 0.0052 15.4 0.0 0.007 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) eIF-3_zeta PF05091.7 KND90444.1 - 1.3e-187 624.5 0.0 1.6e-187 624.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SH3_9 PF14604.1 KND90445.1 - 7.4e-27 92.6 3.4 3.1e-13 49.0 0.3 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 KND90445.1 - 1e-19 69.6 8.9 9.5e-11 40.9 0.6 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KND90445.1 - 1.2e-11 43.9 0.1 6.9e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KND90445.1 - 1.2e-11 44.5 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Chitin_synth_2 PF03142.10 KND90446.1 - 1.1e-23 83.3 3.6 6.3e-22 77.6 1.8 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KND90446.1 - 2.7e-16 59.8 6.6 2.7e-16 59.8 4.6 2.5 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND90446.1 - 2.2e-15 57.1 0.0 5.1e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KND90446.1 - 0.00065 19.4 0.1 0.64 9.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 zf-H2C2_2 PF13465.1 KND90448.1 - 2e-14 53.0 8.7 5.1e-08 32.8 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KND90448.1 - 7.7e-13 47.9 12.2 7.8e-06 25.9 1.6 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND90448.1 - 3.4e-06 26.9 28.4 3.7e-05 23.7 1.8 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 KND90448.1 - 4e-05 23.6 2.3 0.013 15.6 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND90448.1 - 0.0015 18.5 18.5 0.029 14.5 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 KND90448.1 - 0.16 11.6 0.7 0.33 10.6 0.5 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.1 KND90448.1 - 0.2 11.9 0.4 0.46 10.7 0.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.17 KND90448.1 - 0.79 9.8 3.7 6.5 6.8 2.7 2.2 1 1 1 2 2 2 0 LIM domain BAF1_ABF1 PF04684.8 KND90448.1 - 2.4 6.9 10.8 4 6.1 7.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 KND90450.1 - 7.5e-36 123.5 28.6 1.2e-35 122.9 19.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KND90450.1 - 7.3e-05 22.7 0.2 7.3e-05 22.7 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) Fungal_trans_2 PF11951.3 KND90452.1 - 3.5e-09 35.7 2.3 2.3e-08 33.0 1.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90452.1 - 9.2e-05 22.2 5.5 0.00019 21.2 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KND90455.1 - 1.3e-10 41.4 0.0 2.9e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND90455.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase A_deaminase PF00962.17 KND90456.1 - 4.5e-61 206.6 0.0 5.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KND90456.1 - 0.017 15.1 0.2 0.039 14.0 0.1 1.6 1 1 0 1 1 1 0 Amidohydrolase APH PF01636.18 KND90457.1 - 1.1e-05 25.2 0.3 3.7e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KND90457.1 - 0.025 14.4 6.5 0.061 13.2 4.5 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger WD40 PF00400.27 KND90459.1 - 1.1e-28 98.0 6.7 4.2e-10 39.1 0.1 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KND90459.1 - 0.0001 20.5 0.1 0.0057 14.8 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KND90459.1 - 0.013 15.2 0.0 0.48 10.1 0.0 3.0 1 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KND90459.1 - 0.1 12.0 0.0 0.98 8.9 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.17 KND90459.1 - 0.15 11.3 0.0 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 Ras family Cyclin_N PF00134.18 KND90460.1 - 9.4e-44 148.0 0.1 1.9e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KND90460.1 - 1.3e-32 112.2 0.0 2.3e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain p450 PF00067.17 KND90461.1 - 3.8e-68 230.1 0.0 1.1e-67 228.6 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KND90461.1 - 6.5e-26 91.0 0.0 5.2e-25 88.1 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 KND90461.1 - 1.4e-25 89.9 0.1 2.4e-21 76.2 0.0 2.8 2 1 1 3 3 3 2 FAD binding domain NAD_binding_1 PF00175.16 KND90461.1 - 2.1e-14 53.9 0.0 6.1e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1493 PF07377.7 KND90461.1 - 0.08 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Flavodoxin_5 PF12724.2 KND90461.1 - 0.085 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain zf-RING_2 PF13639.1 KND90462.1 - 4.8e-14 51.9 16.8 5.6e-14 51.6 4.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND90462.1 - 1.3e-11 43.9 11.1 2.7e-09 36.5 3.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND90462.1 - 3.4e-08 32.9 16.1 2.6e-06 26.9 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND90462.1 - 2.7e-07 30.5 4.2 2.7e-07 30.5 2.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND90462.1 - 3.3e-07 30.2 16.7 7e-07 29.1 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND90462.1 - 1.6e-05 24.5 12.4 2e-05 24.2 3.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KND90462.1 - 0.00012 21.4 2.7 0.00027 20.4 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KND90462.1 - 0.0013 18.5 2.0 0.0013 18.5 1.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 KND90462.1 - 0.0025 17.4 0.1 0.0025 17.4 0.1 2.1 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KND90462.1 - 0.0043 17.0 7.5 0.0077 16.2 2.7 2.5 2 0 0 2 2 2 1 zinc-finger DNA_ligase_ZBD PF03119.11 KND90462.1 - 0.014 15.1 3.2 2.5 7.8 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Baculo_RING PF05883.6 KND90462.1 - 0.08 12.7 5.0 0.12 12.2 1.5 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 KND90462.1 - 0.11 12.2 2.8 0.16 11.6 0.4 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.1 KND90462.1 - 0.38 10.5 14.0 2.5 7.8 0.6 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 KND90462.1 - 0.44 10.4 12.9 0.47 10.3 0.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KND90462.1 - 0.47 10.0 2.9 1 8.9 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KND90462.1 - 0.86 9.2 13.4 0.17 11.4 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KND90462.1 - 2.9 7.7 7.1 2 8.2 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 KND90462.1 - 3.8 7.3 8.8 2.1 8.1 0.3 2.8 2 1 0 3 3 3 0 zinc-ribbons zf-P11 PF03854.9 KND90462.1 - 5.2 6.6 10.4 0.061 12.8 1.7 1.9 2 0 0 2 2 2 0 P-11 zinc finger PHD PF00628.24 KND90462.1 - 6.1 6.6 16.2 1.2 8.8 4.2 2.6 2 1 1 3 3 3 0 PHD-finger zf-RING_2 PF13639.1 KND90463.1 - 4.8e-14 51.9 16.8 5.6e-14 51.6 4.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND90463.1 - 1.3e-11 43.9 11.1 2.7e-09 36.5 3.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND90463.1 - 3.4e-08 32.9 16.1 2.6e-06 26.9 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND90463.1 - 2.7e-07 30.5 4.2 2.7e-07 30.5 2.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND90463.1 - 3.3e-07 30.2 16.7 7e-07 29.1 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND90463.1 - 1.6e-05 24.5 12.4 2e-05 24.2 3.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KND90463.1 - 0.00012 21.4 2.7 0.00027 20.4 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KND90463.1 - 0.0013 18.5 2.0 0.0013 18.5 1.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 KND90463.1 - 0.0025 17.4 0.1 0.0025 17.4 0.1 2.1 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KND90463.1 - 0.0043 17.0 7.5 0.0077 16.2 2.7 2.5 2 0 0 2 2 2 1 zinc-finger DNA_ligase_ZBD PF03119.11 KND90463.1 - 0.014 15.1 3.2 2.5 7.8 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Baculo_RING PF05883.6 KND90463.1 - 0.08 12.7 5.0 0.12 12.2 1.5 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 KND90463.1 - 0.11 12.2 2.8 0.16 11.6 0.4 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.1 KND90463.1 - 0.38 10.5 14.0 2.5 7.8 0.6 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 KND90463.1 - 0.44 10.4 12.9 0.47 10.3 0.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KND90463.1 - 0.47 10.0 2.9 1 8.9 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KND90463.1 - 0.86 9.2 13.4 0.17 11.4 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KND90463.1 - 2.9 7.7 7.1 2 8.2 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 KND90463.1 - 3.8 7.3 8.8 2.1 8.1 0.3 2.8 2 1 0 3 3 3 0 zinc-ribbons zf-P11 PF03854.9 KND90463.1 - 5.2 6.6 10.4 0.061 12.8 1.7 1.9 2 0 0 2 2 2 0 P-11 zinc finger PHD PF00628.24 KND90463.1 - 6.1 6.6 16.2 1.2 8.8 4.2 2.6 2 1 1 3 3 3 0 PHD-finger APH PF01636.18 KND90464.1 - 0.001 18.8 7.7 0.0043 16.8 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 KND90464.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SURF6 PF04935.7 KND90464.1 - 0.0015 17.8 0.5 0.0032 16.7 0.4 1.5 1 0 0 1 1 1 1 Surfeit locus protein 6 Choline_kinase PF01633.15 KND90464.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase TAF4 PF05236.9 KND90464.1 - 0.29 10.3 7.2 0.48 9.6 5.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Methyltransf_18 PF12847.2 KND90466.1 - 7.8e-14 52.2 0.0 1.5e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90466.1 - 1.5e-09 37.6 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND90466.1 - 1.4e-08 34.6 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND90466.1 - 9.3e-08 31.4 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KND90466.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90466.1 - 4.3e-07 30.2 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND90466.1 - 2e-05 24.0 0.0 5.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KND90466.1 - 9.1e-05 22.8 0.0 0.00022 21.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.7 KND90466.1 - 0.00027 20.3 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.12 KND90466.1 - 0.00049 19.2 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 KND90466.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_26 PF13659.1 KND90466.1 - 0.039 13.9 0.1 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 KND90466.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ank_2 PF12796.2 KND90467.1 - 4.3e-69 228.8 0.8 7.3e-21 74.3 0.1 5.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KND90467.1 - 1.1e-68 223.7 0.2 4.6e-07 29.3 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 KND90467.1 - 1.4e-51 167.3 0.2 2.4e-05 24.1 0.0 10.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 KND90467.1 - 5.4e-42 140.8 5.2 2e-08 34.2 0.0 8.6 2 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND90467.1 - 1.1e-41 140.4 7.1 4.2e-10 39.8 0.0 7.2 3 1 4 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.7 KND90467.1 - 2.8e-06 27.0 0.0 7.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KND90467.1 - 9e-05 22.6 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND90467.1 - 0.00014 21.8 0.0 0.00052 20.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PNP_UDP_1 PF01048.15 KND90467.1 - 0.00022 20.2 0.1 0.00036 19.5 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily MMR_HSR1 PF01926.18 KND90467.1 - 0.029 14.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KND90467.1 - 0.036 13.4 0.2 0.096 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 KND90467.1 - 0.048 12.6 1.5 0.94 8.3 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 KND90467.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KND90467.1 - 0.057 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF3962 PF13111.1 KND90467.1 - 0.096 12.0 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) AAA_29 PF13555.1 KND90467.1 - 0.13 11.7 0.0 0.38 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KND90467.1 - 0.15 12.2 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Ribonucleas_3_3 PF14622.1 KND90469.1 - 9.5e-11 41.7 0.0 0.0003 20.7 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KND90469.1 - 4.3e-07 30.3 0.0 9.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 KND90469.1 - 0.0052 17.3 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif APH PF01636.18 KND90470.1 - 2.5e-12 47.0 0.2 3.1e-11 43.4 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND90470.1 - 4e-08 33.0 0.0 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Chromate_transp PF02417.10 KND90472.1 - 6e-43 146.3 37.2 3.7e-27 94.9 10.9 2.5 3 0 0 3 3 3 2 Chromate transporter Methyltransf_23 PF13489.1 KND90473.1 - 5.5e-18 65.1 0.0 7.8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND90473.1 - 2.2e-09 37.8 0.0 3.4e-08 34.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND90473.1 - 4.9e-08 33.3 0.0 3.7e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90473.1 - 5e-08 32.6 0.0 6.9e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND90473.1 - 4.9e-07 30.1 0.0 9.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND90473.1 - 0.00061 19.2 0.0 0.063 12.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KND90473.1 - 0.00081 19.4 0.0 0.059 13.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90473.1 - 0.0015 18.8 0.0 0.0045 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KND90473.1 - 0.0027 17.1 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KND90473.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KND90473.1 - 0.053 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 KND90473.1 - 0.065 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-CCCH PF00642.19 KND90475.1 - 1.9e-08 33.7 2.5 1.9e-08 33.7 1.8 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KND90475.1 - 5.3e-08 32.4 5.8 9.1e-08 31.6 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND90475.1 - 1.4e-07 31.3 10.1 2.6e-07 30.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND90475.1 - 1.3e-06 27.9 9.6 2.4e-06 27.1 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND90475.1 - 4.6e-05 23.1 7.5 7.7e-05 22.4 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KND90475.1 - 5e-05 22.9 8.2 9.2e-05 22.0 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KND90475.1 - 0.0013 18.3 1.4 0.0033 17.1 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KND90475.1 - 0.17 11.7 7.5 0.41 10.5 5.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Harakiri PF15196.1 KND90475.1 - 0.86 9.8 4.3 0.49 10.6 0.9 2.1 2 0 0 2 2 2 0 Activator of apoptosis harakiri Autophagy_N PF03986.8 KND90476.1 - 1.7e-44 151.1 0.1 3.4e-44 150.1 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KND90476.1 - 2.7e-22 78.7 0.7 6.1e-22 77.5 0.2 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KND90476.1 - 1.5e-14 52.8 0.4 2.6e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF2404 PF10296.4 KND90477.1 - 7.7e-30 102.8 0.0 1.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 KND90477.1 - 0.073 13.2 0.0 0.39 10.9 0.0 2.2 2 1 1 3 3 3 0 PH domain Mcp5_PH PF12814.2 KND90478.1 - 5.9e-44 148.9 0.1 1.4e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Peptidase_S8 PF00082.17 KND90479.1 - 1.1e-28 100.1 0.1 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Gp5_C PF06715.7 KND90480.1 - 0.014 15.2 0.4 3.3 7.8 0.3 2.7 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) Aldedh PF00171.17 KND90481.1 - 4.1e-115 384.7 0.7 2.1e-66 224.1 0.0 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family ADH_zinc_N PF00107.21 KND90482.1 - 1.1e-18 66.9 0.2 1.7e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND90482.1 - 2.4e-13 49.7 0.3 6.3e-13 48.4 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 4HBT PF03061.17 KND90484.1 - 2.6e-11 43.4 0.0 5.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Patatin PF01734.17 KND90485.1 - 9e-29 100.8 0.1 1.4e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Trypsin_2 PF13365.1 KND90486.1 - 1.4e-07 31.4 0.0 3.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KND90486.1 - 0.0003 20.4 0.1 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin Antimicrobial20 PF08256.6 KND90486.1 - 2.3 8.7 7.9 1.3 9.5 0.2 4.0 3 0 0 3 3 3 0 Aurein-like antibiotic peptide Pex14_N PF04695.8 KND90487.1 - 0.018 15.0 1.8 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M35 PF02102.10 KND90488.1 - 2.4e-21 75.7 1.9 2.5e-21 75.7 1.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KND90488.1 - 2.6e-05 24.7 0.1 2.9e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF2293 PF10056.4 KND90490.1 - 1.3e-26 92.4 0.2 1.3e-26 92.4 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) LRR_4 PF12799.2 KND90491.1 - 2.1e-38 129.3 36.9 5.3e-08 32.2 0.6 10.4 8 2 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND90491.1 - 6.9e-31 105.7 37.1 2.3e-07 30.4 1.4 8.4 3 2 5 10 10 10 9 Leucine rich repeat LRR_1 PF00560.28 KND90491.1 - 2.9e-17 60.0 37.2 0.21 11.7 0.0 15.3 17 1 0 17 17 17 7 Leucine Rich Repeat LRR_6 PF13516.1 KND90491.1 - 9.8e-07 28.2 23.9 0.74 10.0 0.6 10.6 10 0 0 10 10 10 2 Leucine Rich repeat LRR_7 PF13504.1 KND90491.1 - 1.2e-06 27.7 40.0 6 7.5 0.1 13.8 16 0 0 16 16 16 3 Leucine rich repeat LRR_9 PF14580.1 KND90491.1 - 0.0028 17.2 8.6 0.8 9.2 0.1 4.1 2 2 2 4 4 4 3 Leucine-rich repeat DUF4328 PF14219.1 KND90492.1 - 1.2 8.4 6.6 1.8 7.8 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4328) Cep57_CLD_2 PF14197.1 KND90493.1 - 0.0083 16.0 3.0 0.0083 16.0 2.1 3.0 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 DUF972 PF06156.8 KND90493.1 - 2 8.7 14.5 9.3 6.6 1.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pkinase PF00069.20 KND90494.1 - 0.0098 15.0 0.1 0.078 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DAO PF01266.19 KND90495.1 - 1.8e-45 155.4 1.0 2.4e-45 155.0 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND90495.1 - 3.5e-05 23.6 0.1 0.097 12.4 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KND90495.1 - 0.00025 20.9 0.0 0.0008 19.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KND90495.1 - 0.0041 16.0 0.0 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KND90495.1 - 0.077 11.9 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TBP PF00352.16 KND90496.1 - 3e-69 228.3 0.2 4.3e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KND90496.1 - 0.00016 21.6 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KND90496.1 - 0.00048 20.4 0.6 0.00068 19.9 0.4 1.3 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) DUF4295 PF14128.1 KND90496.1 - 0.096 12.3 0.3 0.3 10.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) UCH_1 PF13423.1 KND90498.1 - 2.1e-57 194.8 0.0 3.1e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KND90498.1 - 1.2e-26 93.9 0.0 2.8e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KND90498.1 - 2.7e-07 29.9 0.0 1.8e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_25 PF13649.1 KND90499.1 - 4.8e-09 36.4 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND90499.1 - 6.8e-06 26.4 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90499.1 - 0.00013 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND90499.1 - 0.0005 20.5 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND90499.1 - 0.0023 18.4 0.0 0.0038 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND90499.1 - 0.003 17.2 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND90499.1 - 0.14 12.2 0.1 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain HpaP PF09483.5 KND90501.1 - 3.2 7.6 9.8 4 7.3 6.8 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) OPT PF03169.10 KND90502.1 - 8.1e-164 546.4 47.7 9.4e-164 546.2 33.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zn_clus PF00172.13 KND90503.1 - 0.0023 17.8 0.6 0.0023 17.8 0.4 2.9 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 KND90504.1 - 1.8e-41 142.2 0.0 4.9e-41 140.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.13 KND90505.1 - 3.8e-09 36.2 11.7 5.8e-09 35.7 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND90505.1 - 2.3e-06 26.6 0.0 7.3e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Copper-fist PF00649.13 KND90506.1 - 4.6e-22 76.9 1.3 4.6e-22 76.9 0.9 4.2 2 2 2 4 4 4 3 Copper fist DNA binding domain Pyr_redox_3 PF13738.1 KND90508.1 - 3.1e-20 73.1 0.0 4.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KND90508.1 - 3.7e-12 45.2 3.6 2e-09 36.1 0.1 2.7 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND90508.1 - 5.7e-09 35.8 0.0 2.2e-07 30.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KND90508.1 - 3e-05 23.1 0.2 0.21 10.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KND90508.1 - 5.5e-05 23.1 1.1 0.0019 18.0 0.8 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND90508.1 - 0.00088 19.6 0.2 1.1 9.6 0.0 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND90508.1 - 0.0011 17.9 0.1 1.4 7.7 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND90508.1 - 0.0018 18.0 6.2 2.6 7.8 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KND90508.1 - 0.031 13.1 1.4 0.4 9.5 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 KND90508.1 - 0.34 9.3 1.3 0.8 8.0 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein PHY PF00360.15 KND90509.1 - 3.4e-24 84.9 0.0 7.4e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KND90509.1 - 9.7e-16 57.4 0.1 1.8e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 KND90509.1 - 2.4e-14 53.7 0.0 7.2e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 KND90509.1 - 1e-12 48.0 0.1 4.7e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KND90509.1 - 2.5e-12 46.6 0.7 2.5e-12 46.6 0.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KND90509.1 - 4e-09 36.8 0.0 1.4e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold DUF3425 PF11905.3 KND90510.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3425) Transket_pyr PF02779.19 KND90511.1 - 1.5e-39 135.2 0.0 2.7e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KND90511.1 - 3.1e-29 101.4 0.0 7.5e-29 100.1 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Glyco_hydro_18 PF00704.23 KND90512.1 - 7.1e-10 38.8 0.5 9.9e-10 38.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KND90513.1 - 1.8e-21 76.9 0.1 1.6e-16 60.6 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.15 KND90513.1 - 7.9e-10 38.4 0.1 0.0002 21.1 0.1 2.4 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KND90513.1 - 6.1e-06 26.1 3.8 6.1e-06 26.1 2.6 3.5 5 0 0 5 5 5 1 Chitin recognition protein Exo_endo_phos_2 PF14529.1 KND90515.1 - 4.6e-06 26.2 0.0 7.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cupin_8 PF13621.1 KND90516.1 - 2.8e-22 79.4 0.0 7.1e-22 78.1 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KND90516.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 KND90516.1 - 0.025 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.17 KND90516.1 - 0.13 12.5 0.0 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Ran-binding PF05508.6 KND90518.1 - 3.2e-101 338.2 0.0 4.2e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein CLASP_N PF12348.3 KND90518.1 - 0.076 12.3 0.2 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 CLASP N terminal DUF4131 PF13567.1 KND90519.1 - 0.16 11.3 0.4 0.24 10.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PEPCK_ATP PF01293.15 KND90520.1 - 1.4e-215 716.2 0.0 1.6e-215 715.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KND90520.1 - 0.045 14.0 0.1 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KND90520.1 - 0.075 12.5 0.1 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KND90520.1 - 0.076 12.8 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KND90520.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 KND90521.1 - 3.5e-44 150.4 0.0 5.8e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KND90521.1 - 4.8e-21 74.7 0.1 1.2e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KND90521.1 - 2.5e-08 33.9 0.1 7.4e-08 32.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND90521.1 - 0.00058 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KND90521.1 - 0.52 8.9 2.6 0.99 8.0 1.8 1.4 1 0 0 1 1 1 0 G-protein alpha subunit FCH PF00611.18 KND90522.1 - 3.3e-21 75.2 1.6 7.6e-21 74.1 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KND90522.1 - 2e-12 46.3 0.0 3.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KND90522.1 - 1.7e-11 43.3 0.0 1.3e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KND90522.1 - 3.4e-10 39.3 0.1 8.9e-10 38.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF4407 PF14362.1 KND90522.1 - 7.7 5.3 11.6 16 4.3 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PhzC-PhzF PF02567.11 KND90523.1 - 1.1e-41 142.8 0.1 2e-41 142.0 0.1 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Methyltransf_23 PF13489.1 KND90525.1 - 9.4e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND90525.1 - 5.3e-05 23.7 0.0 0.00023 21.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND90525.1 - 0.00013 22.3 0.0 0.0009 19.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90525.1 - 0.00033 20.2 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KND90525.1 - 0.00062 20.2 0.0 0.016 15.6 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90525.1 - 0.0025 18.1 0.0 0.0073 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND90525.1 - 0.0031 16.6 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family UPF0029 PF01205.14 KND90526.1 - 7.3e-24 83.5 0.0 2.4e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Pkinase PF00069.20 KND90527.1 - 8.1e-73 244.7 0.0 9.9e-73 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90527.1 - 3.7e-32 111.4 0.0 4.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND90527.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND90527.1 - 0.0044 16.7 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KND90527.1 - 0.0052 15.6 0.1 0.0077 15.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KND90527.1 - 0.04 12.9 0.1 0.091 11.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KND90527.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.13 KND90528.1 - 8.3e-13 47.8 0.0 1.9e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90528.1 - 7.8e-05 22.4 7.6 0.00015 21.6 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ProSAAS PF07259.7 KND90528.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 ProSAAS precursor DUF939_C PF11728.3 KND90528.1 - 0.091 12.5 0.9 0.23 11.2 0.6 1.6 1 0 0 1 1 1 0 DUF939 C-terminal domain TRAUB PF08164.7 KND90529.1 - 6.7e-32 109.4 0.2 1.9e-31 107.9 0.1 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KND90529.1 - 9.1e-28 97.0 0.6 9.1e-28 97.0 0.4 2.9 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.4 KND90530.1 - 6.4e-29 99.6 0.3 1.6e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KND90530.1 - 8.7e-13 48.1 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KND90530.1 - 3.5e-08 33.5 0.0 3.5e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KND90530.1 - 0.00029 20.0 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 KND90530.1 - 0.00074 18.7 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 KND90530.1 - 0.0017 17.4 0.3 0.016 14.2 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 KND90530.1 - 0.003 17.2 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND90530.1 - 0.015 14.7 0.1 0.078 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 KND90530.1 - 0.037 13.3 0.1 0.055 12.8 0.1 1.3 1 1 0 1 1 1 0 YhjQ protein AAA_19 PF13245.1 KND90530.1 - 0.22 11.2 1.1 6.3 6.6 0.1 2.6 2 1 0 2 2 2 0 Part of AAA domain DUF4537 PF15057.1 KND90531.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) RRM_1 PF00076.17 KND90532.1 - 3.3e-07 29.8 0.1 6.6e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND90532.1 - 3.5e-05 23.6 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND90532.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3862 PF12978.2 KND90532.1 - 0.072 12.7 0.4 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3862) Aminotran_3 PF00202.16 KND90534.1 - 4.9e-87 291.9 0.0 5.8e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 KND90535.1 - 4.2e-19 68.4 0.6 1.2e-18 66.9 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90535.1 - 2.4e-05 24.1 9.8 5.2e-05 23.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2046 PF09755.4 KND90536.1 - 0.066 12.0 3.5 0.57 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF1590 PF07629.6 KND90537.1 - 0.13 11.9 0.8 0.96 9.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) MFS_1 PF07690.11 KND90538.1 - 5.8e-38 130.5 34.9 5.8e-38 130.5 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND90538.1 - 4.5e-08 32.0 21.9 8.6e-08 31.1 15.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KND90538.1 - 1e-05 23.9 2.0 1e-05 23.9 1.4 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KND90538.1 - 4.2e-05 21.8 1.4 6.4e-05 21.2 1.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Cellulase PF00150.13 KND90539.1 - 4.8e-12 45.6 0.5 4.8e-12 45.6 0.4 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 KND90539.1 - 0.047 14.0 0.0 0.047 14.0 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MIP-T3 PF10243.4 KND90539.1 - 0.13 10.7 16.4 0.17 10.3 11.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AA_permease_2 PF13520.1 KND90539.1 - 0.16 10.4 0.1 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Amino acid permease DUF1510 PF07423.6 KND90539.1 - 0.22 10.8 0.1 0.22 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 KND90539.1 - 0.77 9.2 2.8 19 4.6 1.4 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Protocadherin PF08374.6 KND90539.1 - 1 8.9 0.0 1 8.9 0.0 2.4 2 1 0 2 2 2 0 Protocadherin Flavokinase PF01687.12 KND90540.1 - 2e-37 127.8 0.0 2.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 KND90541.1 - 0.0021 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold zf-RING_2 PF13639.1 KND90542.1 - 4.5e-10 39.1 6.0 7e-10 38.5 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KND90542.1 - 8e-09 35.4 1.5 1.3e-08 34.7 1.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KND90542.1 - 1.2e-05 25.0 3.0 3.8e-05 23.4 2.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KND90542.1 - 0.0037 16.9 4.1 0.0072 15.9 2.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KND90542.1 - 0.025 14.3 0.8 0.056 13.1 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 KND90542.1 - 0.036 13.6 1.7 0.11 12.0 0.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KND90542.1 - 0.048 13.3 4.0 0.078 12.6 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND90542.1 - 0.098 12.6 6.7 0.17 11.9 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND90542.1 - 0.17 11.6 2.3 0.31 10.7 1.6 1.5 1 1 0 1 1 1 0 zinc-RING finger domain NAD_binding_10 PF13460.1 KND90543.1 - 1.6e-12 47.8 0.6 3.2e-12 46.8 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND90543.1 - 5.3e-07 29.3 0.0 8.5e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND90543.1 - 1.4e-05 24.5 0.1 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.5 KND90543.1 - 0.00047 18.7 0.0 0.0023 16.4 0.0 1.8 1 1 1 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 KND90543.1 - 0.00075 18.4 0.0 1.5 7.6 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KND90543.1 - 0.0033 16.1 0.0 0.0061 15.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KND90543.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KND90544.1 - 2.2e-26 92.7 2.9 3.3e-26 92.1 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND90544.1 - 3e-17 63.1 0.9 1.5e-15 57.6 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND90544.1 - 9.7e-12 44.9 1.5 1.8e-11 44.0 1.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KND90544.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3632 PF12311.3 KND90545.1 - 2e-41 141.8 5.5 2.5e-41 141.4 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans_2 PF11951.3 KND90546.1 - 2.4e-22 79.0 0.1 2e-19 69.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain PIN_4 PF13638.1 KND90546.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 PIN domain zf-C2H2_4 PF13894.1 KND90547.1 - 0.00093 19.3 2.5 0.31 11.4 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KND90547.1 - 7 7.2 12.1 2.5 8.5 0.1 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type Methyltransf_33 PF10017.4 KND90549.1 - 2.9e-21 75.6 0.0 4.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Shikimate_dh_N PF08501.6 KND90549.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain zf-DBF PF07535.7 KND90550.1 - 0.11 12.1 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 DBF zinc finger SDF PF00375.13 KND90551.1 - 8.6e-07 28.0 2.7 9.6e-07 27.8 1.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DAO PF01266.19 KND90552.1 - 6.1e-42 143.7 0.0 8.2e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND90552.1 - 2.6e-08 34.0 0.5 9.4e-06 25.6 0.6 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND90552.1 - 1.1e-06 28.5 0.0 4.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND90552.1 - 5.8e-06 26.6 0.0 1.8e-05 25.0 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KND90552.1 - 5.9e-06 25.3 0.2 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KND90552.1 - 0.00084 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KND90552.1 - 0.00084 18.0 0.1 0.095 11.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KND90552.1 - 0.00095 18.9 0.1 2 8.2 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KND90552.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 KND90552.1 - 0.0019 18.3 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND90552.1 - 0.0034 15.9 0.8 0.04 12.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 KND90552.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.13 KND90552.1 - 0.0052 16.4 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KND90552.1 - 0.0083 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KND90552.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KND90552.1 - 0.016 14.0 4.5 0.24 10.1 3.1 2.2 1 1 0 1 1 1 0 FAD binding domain adh_short PF00106.20 KND90552.1 - 0.034 14.0 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND90552.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 KND90552.1 - 0.09 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_1 PF00667.15 KND90553.1 - 2.5e-63 213.4 0.0 8.6e-63 211.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KND90553.1 - 6e-12 46.0 0.0 1.1e-10 42.0 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 KND90553.1 - 2.9e-07 30.5 0.0 7.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KND90553.1 - 7e-05 22.7 0.3 0.00019 21.3 0.2 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Atx10homo_assoc PF09759.4 KND90554.1 - 4.6e-11 42.3 0.0 1.7e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.15 KND90555.1 - 1.2e-38 132.4 0.3 1.4e-38 132.2 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SNF2_N PF00176.18 KND90557.1 - 9.9e-76 254.3 0.2 2.3e-75 253.2 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND90557.1 - 2.1e-12 46.7 0.0 5.3e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 KND90557.1 - 0.053 12.2 0.1 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 NinG PF05766.7 KND90557.1 - 0.085 12.5 6.8 0.18 11.5 4.7 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Cytochrom_c3_2 PF14537.1 KND90557.1 - 0.4 11.0 7.2 1.2 9.5 5.0 1.8 1 0 0 1 1 1 0 Cytochrome c3 VHS PF00790.14 KND90558.1 - 3.5e-37 127.1 0.1 8.5e-37 125.9 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KND90558.1 - 1.4e-16 59.8 1.5 1.5e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KND90558.1 - 2.8e-16 58.6 0.5 6.3e-16 57.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KND90558.1 - 1.1e-13 50.3 0.0 2.2e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KND90558.1 - 0.014 15.3 0.9 0.053 13.4 0.7 1.9 1 0 0 1 1 1 0 GAT domain UIM PF02809.15 KND90558.1 - 0.13 11.9 3.6 0.33 10.6 2.5 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.15 KND90558.1 - 0.13 11.6 0.2 0.32 10.4 0.1 1.6 1 0 0 1 1 1 0 TIR domain Mito_carr PF00153.22 KND90559.1 - 1.4e-63 210.6 4.3 8.2e-26 89.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KND90559.1 - 0.35 10.9 2.7 0.4 10.7 0.1 2.5 3 1 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family RCC1 PF00415.13 KND90560.1 - 7.4e-20 70.9 1.0 1.2e-05 25.4 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KND90560.1 - 5.4e-14 52.1 0.0 2.5e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KND90560.1 - 1.1e-10 41.7 0.1 1.3e-08 35.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KND90560.1 - 2.9e-06 26.7 6.0 9.3e-05 21.9 0.7 3.6 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KND90560.1 - 1.7e-05 24.5 0.0 0.21 11.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KND90560.1 - 0.0049 17.1 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND90560.1 - 0.075 13.3 0.1 1.6 9.1 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.27 KND90561.1 - 1.2e-15 55.5 6.8 1.9e-05 23.6 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KND90561.1 - 1e-14 54.3 3.9 1.6e-09 37.7 2.7 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KND90561.1 - 6e-14 51.3 10.9 6.5e-11 41.6 2.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KND90561.1 - 1.7e-11 42.9 3.8 0.00062 19.4 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KND90561.1 - 6.5e-09 34.7 1.0 0.00012 21.2 0.1 3.4 3 0 0 3 3 3 2 EF hand Spc7_N PF15402.1 KND90561.1 - 0.079 10.9 1.5 0.11 10.4 1.0 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 EF-hand_like PF09279.6 KND90561.1 - 0.16 12.0 1.5 0.18 11.8 0.4 1.5 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Nup96 PF12110.3 KND90562.1 - 3.9e-80 269.0 0.1 6e-80 268.4 0.1 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KND90562.1 - 2.8e-45 153.5 0.0 4.9e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KND90562.1 - 8.7e-19 67.8 244.9 2.1e-08 34.3 27.7 11.5 4 2 7 12 12 12 7 Nucleoporin FG repeat region zf-C2H2 PF00096.21 KND90563.1 - 7.5e-21 73.1 28.1 1.4e-05 25.1 0.1 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND90563.1 - 5.5e-20 70.5 33.9 4.4e-07 29.8 1.2 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND90563.1 - 2e-13 49.6 27.1 0.0014 18.8 0.1 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND90563.1 - 1.1e-08 34.9 5.5 0.047 13.8 0.3 4.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND90563.1 - 0.0015 18.3 16.2 0.77 9.7 0.6 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KND90563.1 - 0.0027 17.8 12.2 1.6 9.0 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type C1_4 PF07975.7 KND90563.1 - 0.019 14.9 0.4 6 6.9 0.0 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain Yippee-Mis18 PF03226.9 KND90563.1 - 0.47 10.5 2.2 0.93 9.5 0.6 2.1 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-ribbon_8 PF09723.5 KND90563.1 - 0.59 10.1 10.6 14 5.7 0.2 3.9 3 1 0 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 KND90563.1 - 0.77 9.5 8.3 0.24 11.1 2.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.1 KND90563.1 - 1.4 8.6 6.4 1.1 9.0 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Lin-8 PF03353.10 KND90563.1 - 3.7 6.7 5.2 1.6 7.9 0.0 2.1 1 1 0 2 2 2 0 Ras-mediated vulval-induction antagonist XPA_N PF01286.13 KND90563.1 - 8.2 6.1 10.4 1.6 8.4 0.2 3.5 4 0 0 4 4 4 0 XPA protein N-terminal DSBA PF01323.15 KND90564.1 - 3e-19 69.3 0.0 3.5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 KND90564.1 - 0.038 14.1 0.0 7.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KND90564.1 - 0.049 13.6 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin PEMT PF04191.8 KND90565.1 - 6.9e-33 112.9 2.8 1.1e-32 112.2 1.9 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase Nramp PF01566.13 KND90566.1 - 4.2e-86 288.9 17.7 4.2e-86 288.9 12.3 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein VHS PF00790.14 KND90566.1 - 8.6e-25 87.0 0.0 3.4e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KND90566.1 - 6.7e-10 38.8 1.3 1.3e-09 37.8 0.9 1.4 1 0 0 1 1 1 1 GAT domain F-actin_cap_A PF01267.12 KND90567.1 - 4.9e-89 297.9 0.0 3.6e-88 295.1 0.0 1.8 1 1 0 1 1 1 1 F-actin capping protein alpha subunit DUF3993 PF13158.1 KND90567.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) TFIIE_beta PF02186.10 KND90568.1 - 9.4e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain Cyt-b5 PF00173.23 KND90569.1 - 1.1e-25 89.2 0.2 1.4e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ETF_QO PF05187.8 KND90570.1 - 9.2e-42 141.5 0.0 1.5e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KND90570.1 - 1.8e-09 36.9 0.0 0.00011 21.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND90570.1 - 3.8e-08 33.2 0.0 9.1e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND90570.1 - 2.2e-05 23.4 0.5 0.0027 16.5 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KND90570.1 - 2.4e-05 24.2 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND90570.1 - 0.00027 19.5 0.4 0.00043 18.8 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KND90570.1 - 0.00037 19.6 0.0 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KND90570.1 - 0.00037 19.6 0.1 0.00085 18.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KND90570.1 - 0.00066 19.4 0.1 0.0062 16.3 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND90570.1 - 0.00096 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND90570.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND90570.1 - 0.0019 18.5 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND90570.1 - 0.0025 16.5 0.1 0.21 10.1 0.1 2.2 1 1 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 KND90570.1 - 0.023 13.6 0.3 0.034 13.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KND90570.1 - 0.061 12.1 0.3 0.093 11.5 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UvrD_C PF13361.1 KND90572.1 - 5.8e-76 256.2 0.0 7.9e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KND90572.1 - 6.3e-63 212.9 1.6 1.4e-61 208.5 0.1 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KND90572.1 - 6.5e-14 51.9 0.0 1.8e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KND90572.1 - 2.7e-11 43.0 0.2 2.7e-11 43.0 0.1 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KND90572.1 - 8.5e-06 25.4 0.3 0.0017 17.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KND90572.1 - 3.5e-05 23.4 0.2 0.35 10.3 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 KND90572.1 - 0.0024 17.2 0.1 0.039 13.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KND90572.1 - 0.099 12.1 0.9 0.36 10.3 0.2 2.3 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 KND90573.1 - 2.5e-81 267.2 6.1 3.3e-21 74.7 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND90573.1 - 1e-52 175.9 0.8 8.3e-14 51.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND90573.1 - 3.5e-39 132.4 0.1 1.3e-09 37.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KND90573.1 - 1.7e-28 98.1 1.0 6.6e-28 96.1 0.6 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KND90573.1 - 0.00012 21.7 0.0 9.8 6.0 0.0 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KND90573.1 - 0.0098 16.1 5.3 2.8 8.2 0.0 4.2 4 0 0 4 4 3 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 KND90573.1 - 0.012 15.0 0.9 5.8 6.4 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 KND90573.1 - 0.019 14.7 4.0 5.4 6.8 0.1 3.5 3 0 0 3 3 3 0 Limkain b1 TC1 PF15063.1 KND90573.1 - 0.089 12.3 0.9 15 5.2 0.0 3.1 3 0 0 3 3 3 0 Thyroid cancer protein 1 RNA_polI_A34 PF08208.6 KND90573.1 - 0.39 10.3 19.9 0.9 9.1 13.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2457 PF10446.4 KND90573.1 - 8.3 5.0 24.5 2.5 6.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ribosomal_S7 PF00177.16 KND90575.1 - 5e-24 84.5 0.0 8.4e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CcmD PF04995.9 KND90576.1 - 0.07 12.8 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2014 PF09427.5 KND90577.1 - 3.7e-97 324.5 6.6 5.5e-97 323.9 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KND90577.1 - 5.9e-18 64.3 0.6 1.3e-17 63.2 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC155 PF14662.1 KND90577.1 - 0.083 12.4 2.0 0.28 10.7 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Ceramidase_alk PF04734.8 KND90579.1 - 2.6e-273 908.0 0.0 2.9e-273 907.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Usp PF00582.21 KND90580.1 - 1.4e-22 80.3 1.5 6.6e-20 71.7 1.1 2.8 1 1 0 1 1 1 1 Universal stress protein family NMO PF03060.10 KND90581.1 - 4.2e-53 180.6 1.0 5.8e-53 180.1 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KND90581.1 - 3.1e-05 23.0 0.1 0.0015 17.5 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DUF1902 PF08972.6 KND90581.1 - 0.018 14.6 0.0 0.067 12.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1902) Glu_synthase PF01645.12 KND90581.1 - 0.15 10.9 0.6 0.49 9.2 0.4 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase F-box-like PF12937.2 KND90582.1 - 0.0077 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.16 KND90584.1 - 2.1e-38 132.2 0.0 2.9e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND90584.1 - 0.079 11.2 0.2 0.45 8.7 0.1 1.9 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.4 KND90585.1 - 1.3e-55 187.5 1.2 2.2e-55 186.7 0.2 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KND90585.1 - 2.1e-15 56.9 0.0 6.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 KND90585.1 - 0.77 9.7 5.2 1.1 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND90585.1 - 5.1 7.7 7.2 5.3 7.7 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 KND90586.1 - 8.6e-66 222.0 0.0 2e-47 161.6 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KND90586.1 - 3.8e-10 40.1 0.0 0.00073 19.9 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KND90586.1 - 1.8e-08 34.2 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND90586.1 - 9e-08 32.6 0.0 2.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND90586.1 - 1.3e-07 32.0 0.0 1.4e-06 28.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90586.1 - 1.1e-06 28.2 0.0 7.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90586.1 - 2.5e-06 27.7 0.0 6.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KND90586.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.1 KND90586.1 - 0.0043 15.6 2.4 0.0047 15.5 0.1 1.8 2 0 0 2 2 2 1 Raftlin Spore_coat_CotO PF14153.1 KND90586.1 - 1.3 8.4 8.9 0.4 10.1 0.7 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Med13_C PF06333.7 KND90587.1 - 3.6e-100 335.4 1.2 3.7e-100 335.4 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KND90587.1 - 3.9e-24 85.0 0.0 6.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 KND90588.1 - 1.5e-13 50.0 1.3 3.4e-13 48.9 0.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KND90588.1 - 2.4e-06 27.2 0.1 0.0016 18.2 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Toxin-JAB1 PF15659.1 KND90588.1 - 0.003 17.4 0.2 0.0095 15.8 0.2 1.8 1 0 0 1 1 1 1 JAB-like toxin 1 SchA_CurD PF04486.7 KND90589.1 - 0.049 13.4 0.2 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 SchA/CurD like domain Neur_chan_memb PF02932.11 KND90589.1 - 0.058 13.2 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.11 KND90591.1 - 2.8e-23 82.1 39.2 2.8e-23 82.1 27.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyoxalase_2 PF12681.2 KND90591.1 - 1.1e-09 38.7 0.0 2.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Sugar_tr PF00083.19 KND90591.1 - 9.4e-09 34.3 8.2 2.6e-08 32.9 5.7 1.7 1 0 0 1 1 1 1 Sugar (and other) transporter Glyoxalase PF00903.20 KND90591.1 - 0.03 14.3 0.0 0.071 13.0 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Myosin_tail_1 PF01576.14 KND90592.1 - 1.1e-05 23.3 8.3 1.1e-05 23.3 5.8 2.1 1 1 1 2 2 2 1 Myosin tail Bcr-Abl_Oligo PF09036.5 KND90592.1 - 0.0044 16.9 3.7 1 9.3 0.1 3.4 2 1 1 3 3 3 1 Bcr-Abl oncoprotein oligomerisation domain HALZ PF02183.13 KND90592.1 - 0.0052 16.4 0.9 0.11 12.2 0.0 3.2 2 1 0 2 2 2 1 Homeobox associated leucine zipper IncA PF04156.9 KND90592.1 - 0.0092 15.5 20.1 0.04 13.4 2.7 2.3 1 1 1 2 2 2 1 IncA protein Tropomyosin PF00261.15 KND90592.1 - 0.021 13.8 22.9 0.071 12.1 15.8 1.8 1 1 0 1 1 1 0 Tropomyosin Reo_sigmaC PF04582.7 KND90592.1 - 0.025 13.7 0.4 1.1 8.3 0.0 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PRCC PF10253.4 KND90592.1 - 0.06 14.0 2.8 0.14 12.8 1.9 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting KIP1 PF07765.7 KND90592.1 - 0.099 12.4 0.8 0.37 10.6 0.6 2.1 1 0 0 1 1 1 0 KIP1-like protein CENP-F_leu_zip PF10473.4 KND90592.1 - 0.26 11.1 18.9 1.2 8.9 7.9 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 KND90592.1 - 0.27 9.4 16.2 0.41 8.8 11.2 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.1 KND90592.1 - 0.82 8.0 6.7 0.31 9.4 2.0 1.7 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.3 KND90592.1 - 0.86 6.8 19.9 1.2 6.3 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.8 KND90592.1 - 1.1 8.2 2.5 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein PilJ PF13675.1 KND90592.1 - 1.2 9.5 13.3 2 8.7 3.8 3.2 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term HlyD_2 PF12700.2 KND90592.1 - 1.2 8.1 3.4 1.9 7.5 2.3 1.2 1 0 0 1 1 1 0 HlyD family secretion protein LXG PF04740.7 KND90592.1 - 2.1 8.0 8.7 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily Kinesin-relat_1 PF12711.2 KND90592.1 - 3.5 8.0 14.1 0.56 10.6 3.2 2.6 1 1 1 2 2 2 0 Kinesin motor APH PF01636.18 KND90594.1 - 6.1e-15 55.6 0.2 1.5e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND90594.1 - 0.046 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DDE_Tnp_IS66 PF03050.9 KND90594.1 - 0.074 12.2 0.5 0.12 11.5 0.3 1.3 1 0 0 1 1 1 0 Transposase IS66 family DUF2451 PF10474.4 KND90594.1 - 0.12 12.1 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Chromo_shadow PF01393.14 KND90596.1 - 1.7e-13 50.2 1.9 4.8e-12 45.5 0.0 2.9 4 0 0 4 4 4 1 Chromo shadow domain Chromo PF00385.19 KND90596.1 - 1.2e-08 34.4 0.1 1.2e-08 34.4 0.0 2.8 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Herpes_pp85 PF04637.7 KND90596.1 - 0.11 10.7 1.0 0.18 10.0 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DNA_pol_phi PF04931.8 KND90596.1 - 6.1 4.4 7.7 6.4 4.4 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.7 KND90596.1 - 6.3 5.9 8.4 9.9 5.3 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein zf-Di19 PF05605.7 KND90597.1 - 0.011 15.8 0.1 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 KND90597.1 - 0.045 13.5 0.5 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-ribbon_3 PF13248.1 KND90597.1 - 0.1 11.8 0.4 0.2 10.9 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 KND90597.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KND90597.1 - 0.14 12.5 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF972 PF06156.8 KND90597.1 - 0.39 11.0 2.4 0.89 9.9 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF239 PF03080.10 KND90598.1 - 1.5e-37 128.8 5.2 1.9e-37 128.5 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF239) BSD PF03909.12 KND90600.1 - 3.7e-17 61.8 0.3 7.8e-17 60.7 0.2 1.6 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.9 KND90600.1 - 0.026 14.1 0.3 0.085 12.4 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 region 2 HisKA_3 PF07730.8 KND90600.1 - 0.074 13.4 1.0 5.1 7.5 0.0 2.8 2 1 0 2 2 2 0 Histidine kinase TelA PF05816.6 KND90600.1 - 0.082 11.6 3.2 0.073 11.7 1.2 1.6 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Syntaxin-6_N PF09177.6 KND90600.1 - 4.1 7.8 8.3 16 5.9 0.1 3.5 3 1 2 5 5 5 0 Syntaxin 6, N-terminal WGG PF10273.4 KND90601.1 - 2.4e-31 107.6 0.7 4.5e-31 106.7 0.1 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KND90601.1 - 0.39 10.7 0.0 0.39 10.7 0.0 2.2 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) SDA1 PF05285.7 KND90601.1 - 1.3 8.1 11.2 1.1 8.4 7.1 1.3 1 1 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.5 KND90601.1 - 2.8 8.2 8.6 8 6.7 6.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_3 PF07859.8 KND90602.1 - 1.5e-41 142.3 0.1 9.2e-32 110.3 0.0 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KND90602.1 - 2.1e-12 46.4 0.0 7.8e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KND90602.1 - 3.2e-05 22.8 0.0 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KND90602.1 - 0.00017 21.3 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND90602.1 - 0.00056 19.8 0.3 0.0017 18.2 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family MRP-L27 PF09809.4 KND90603.1 - 1.4e-12 47.2 0.6 6.8e-12 44.9 0.2 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 Gryzun PF07919.7 KND90604.1 - 6e-97 325.2 0.0 7.3e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KND90604.1 - 5.8e-75 251.9 1.0 1.4e-69 234.3 1.7 2.4 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KND90604.1 - 0.00092 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1622 PF07784.6 KND90604.1 - 0.025 14.2 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) MFS_1 PF07690.11 KND90605.1 - 1.6e-37 129.0 61.3 4.8e-37 127.4 42.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KND90605.1 - 5.1e-12 44.7 19.8 6.6e-12 44.4 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mito_fiss_reg PF05308.6 KND90606.1 - 0.33 10.3 14.1 0.086 12.2 6.4 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator NeA_P2 PF12312.3 KND90606.1 - 0.66 9.1 7.7 7.1 5.7 2.2 2.2 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Abhydrolase_6 PF12697.2 KND90607.1 - 1.8e-29 103.2 8.0 1.8e-29 103.2 5.6 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND90607.1 - 1.6e-06 27.9 0.2 3.1e-06 27.0 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND90607.1 - 6.7e-06 25.8 0.0 1.6e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 KND90607.1 - 0.00032 19.2 0.0 0.00053 18.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 KND90607.1 - 0.0046 16.4 0.4 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 KND90607.1 - 0.0052 16.0 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 KND90607.1 - 0.013 15.0 0.4 0.029 13.9 0.0 1.8 2 1 0 2 2 2 0 Serine hydrolase Piwi PF02171.12 KND90608.1 - 1.3e-68 231.2 0.0 2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KND90608.1 - 9.7e-12 44.3 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KND90608.1 - 5.5e-07 28.8 0.1 1.8e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Strabismus PF06638.6 KND90608.1 - 0.039 12.2 0.1 0.073 11.3 0.1 1.3 1 0 0 1 1 1 0 Strabismus protein Suc_Fer-like PF06999.7 KND90609.1 - 1.9e-29 103.2 0.0 3.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.16 KND90609.1 - 1.7e-10 40.4 0.0 3.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF913 PF06025.7 KND90609.1 - 0.43 9.2 1.5 14 4.3 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Peptidase_S10 PF00450.17 KND90610.1 - 4.2e-37 128.3 2.3 5.5e-37 127.9 1.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UQ_con PF00179.21 KND90612.1 - 2.3e-26 91.9 0.2 3.1e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Flavi_M PF01004.14 KND90612.1 - 0.15 11.4 1.8 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Bac_surface_Ag PF01103.18 KND90613.1 - 7e-37 127.5 0.0 8.8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ABC2_membrane PF01061.19 KND90614.1 - 4.5e-91 303.6 61.4 5.7e-48 162.8 12.3 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KND90614.1 - 3e-38 129.6 8.5 1.9e-33 114.2 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KND90614.1 - 1.5e-35 122.4 0.0 2.4e-16 60.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KND90614.1 - 6.2e-25 87.0 0.0 2.2e-24 85.3 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KND90614.1 - 1.1e-07 31.5 0.1 0.00036 19.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND90614.1 - 1.4e-07 31.7 0.1 3.9e-05 23.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KND90614.1 - 2.7e-05 23.4 0.0 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KND90614.1 - 3.1e-05 23.8 0.0 0.081 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND90614.1 - 9.1e-05 21.9 0.4 0.025 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KND90614.1 - 0.0003 20.2 0.5 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KND90614.1 - 0.00042 20.4 0.1 0.31 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND90614.1 - 0.0014 19.4 0.0 2.1 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND90614.1 - 0.0028 17.3 0.0 2 8.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KND90614.1 - 0.0036 16.9 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 KND90614.1 - 0.0051 16.2 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_21 PF13304.1 KND90614.1 - 0.0056 16.6 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KND90614.1 - 0.02 15.2 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KND90614.1 - 0.043 14.0 0.0 6.3 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KND90614.1 - 0.046 12.9 0.0 7.8 5.6 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KND90614.1 - 0.059 13.0 0.5 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KND90614.1 - 0.073 13.0 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KND90614.1 - 0.15 12.3 0.1 0.51 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KND90614.1 - 0.18 11.2 1.0 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KND90614.1 - 0.26 11.8 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Viral_helicase1 PF01443.13 KND90614.1 - 0.28 10.6 0.0 7.1 6.0 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KND90614.1 - 0.35 10.5 0.0 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 KND90614.1 - 1.3 7.9 0.0 2.1 7.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Acetyltransf_1 PF00583.19 KND90616.1 - 3.4e-07 30.1 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND90616.1 - 0.002 18.2 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND90616.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Vint PF14623.1 KND90618.1 - 7.6e-53 178.3 0.0 1.7e-52 177.1 0.0 1.6 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KND90618.1 - 1.3e-31 108.4 0.0 2.5e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 KND90618.1 - 1.7e-18 67.3 0.0 3.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KND90618.1 - 3.3e-17 62.7 0.0 6.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KND90618.1 - 3.8e-15 55.9 0.1 1.2e-13 51.0 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain Hint_2 PF13403.1 KND90618.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Hint domain Hint PF01079.15 KND90618.1 - 0.018 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Hint module vWA-TerF-like PF10138.4 KND90618.1 - 0.091 12.5 0.0 0.68 9.7 0.0 2.0 1 1 0 1 1 1 0 vWA found in TerF C terminus Thiolase_N PF00108.18 KND90619.1 - 1.4e-71 240.6 1.2 1.8e-71 240.2 0.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND90619.1 - 1.1e-40 137.8 2.8 1.2e-40 137.7 0.1 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KND90619.1 - 0.0033 16.9 4.3 0.0062 16.0 2.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KND90619.1 - 0.12 12.0 3.2 1.5 8.5 0.4 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Rad4 PF03835.10 KND90620.1 - 4.3e-29 100.7 0.2 9.9e-29 99.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KND90620.1 - 3.1e-26 90.8 0.1 5.8e-26 90.0 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KND90620.1 - 3.7e-22 77.6 0.0 7.7e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KND90620.1 - 5e-11 42.7 0.7 5e-11 42.7 0.5 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KND90620.1 - 0.0049 17.0 0.7 0.047 13.9 0.5 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily ABC_tran PF00005.22 KND90621.1 - 6.7e-49 165.7 0.2 3.2e-27 95.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KND90621.1 - 2.8e-29 102.2 42.0 2.1e-20 73.0 11.7 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 KND90621.1 - 1.7e-23 84.0 0.2 1.5e-09 38.2 0.1 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KND90621.1 - 1.9e-11 43.2 0.6 3.4e-05 23.3 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 KND90621.1 - 9.6e-09 34.7 2.6 0.044 13.0 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND90621.1 - 1.8e-05 25.1 15.3 0.0013 19.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KND90621.1 - 6.3e-05 22.2 0.3 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND90621.1 - 0.0007 19.6 6.7 0.16 11.9 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain ArgK PF03308.11 KND90621.1 - 0.0021 16.8 1.0 0.034 12.9 0.1 2.4 2 0 0 2 2 2 1 ArgK protein ABC2_membrane PF01061.19 KND90621.1 - 0.0024 17.0 17.5 0.0024 17.0 12.1 4.6 5 0 0 5 5 5 2 ABC-2 type transporter AAA_25 PF13481.1 KND90621.1 - 0.0024 17.3 0.1 1.7 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KND90621.1 - 0.0025 16.9 0.0 0.09 11.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KND90621.1 - 0.024 14.4 0.2 8 6.3 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KND90621.1 - 0.031 14.4 0.4 5.7 7.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 KND90621.1 - 0.038 13.4 0.6 6.1 6.2 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MutS_V PF00488.16 KND90621.1 - 0.064 12.6 0.1 5 6.4 0.0 2.5 2 0 0 2 2 2 0 MutS domain V AAA_10 PF12846.2 KND90621.1 - 0.066 12.6 1.3 7.2 5.9 0.3 2.4 2 0 0 2 2 2 0 AAA-like domain Spore_coat_CotO PF14153.1 KND90621.1 - 0.068 12.6 1.5 0.14 11.5 1.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO AAA_17 PF13207.1 KND90621.1 - 0.17 12.6 0.1 23 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KND90621.1 - 0.24 11.2 1.2 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 KND90621.1 - 0.48 10.3 7.2 2.2 8.2 0.2 3.3 3 0 0 3 3 3 0 AAA domain DDHD PF02862.12 KND90621.1 - 1 9.1 3.7 1.9 8.2 2.6 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 KND90621.1 - 1.2 7.1 16.7 1.8 6.5 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NB-ARC PF00931.17 KND90621.1 - 1.2 7.8 1.9 5.9 5.6 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.7 KND90621.1 - 1.3 8.1 8.2 2.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin Apt1 PF10351.4 KND90621.1 - 1.4 7.7 5.4 2.1 7.0 3.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1510 PF07423.6 KND90621.1 - 1.4 8.2 10.7 2.6 7.3 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spt5_N PF11942.3 KND90621.1 - 1.4 9.5 18.9 0.36 11.4 10.3 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal adh_short PF00106.20 KND90622.1 - 4.5e-23 81.9 1.5 3.5e-22 79.0 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND90622.1 - 3.5e-14 53.1 1.7 1.2e-13 51.4 1.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND90622.1 - 2.3e-11 43.6 0.5 1e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KND90622.1 - 0.00037 20.6 0.1 0.00068 19.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KND90622.1 - 0.00066 18.7 0.1 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KND90622.1 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND90622.1 - 0.002 18.1 0.5 0.0065 16.4 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 KND90622.1 - 0.0029 17.9 0.4 0.0073 16.7 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KND90622.1 - 0.03 13.0 0.0 0.05 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KND90622.1 - 0.042 12.7 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AA_kinase PF00696.23 KND90622.1 - 0.045 13.3 0.6 1.3 8.5 0.6 2.0 1 1 1 2 2 2 0 Amino acid kinase family DFP PF04127.10 KND90622.1 - 0.059 12.9 0.2 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Bacteriocin_IId PF09221.5 KND90622.1 - 0.076 12.9 0.8 0.32 10.9 0.5 2.1 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like Mito_carr PF00153.22 KND90623.1 - 3.7e-55 183.6 5.3 3.3e-20 71.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein BUD22 PF09073.5 KND90625.1 - 1.8e-71 241.5 22.1 2.1e-71 241.3 15.3 1.0 1 0 0 1 1 1 1 BUD22 Cyto_heme_lyase PF01265.12 KND90626.1 - 4.1e-74 249.4 0.0 4.7e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DbpA PF03880.10 KND90627.1 - 0.0063 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 KND90627.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND90627.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TCO89 PF10452.4 KND90628.1 - 0.17 10.7 0.1 0.17 10.7 0.0 3.8 3 1 1 4 4 4 0 TORC1 subunit TCO89 ABC1 PF03109.11 KND90629.1 - 1.1e-24 86.7 0.0 1.7e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KND90629.1 - 0.0036 17.0 0.1 0.01 15.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND90629.1 - 0.12 11.7 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family MOZ_SAS PF01853.13 KND90630.1 - 7.5e-79 263.3 0.1 1.1e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KND90630.1 - 3.9e-05 23.2 1.6 3.9e-05 23.2 1.1 2.2 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.15 KND90630.1 - 0.011 15.1 0.8 0.025 14.0 0.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PHD_2 PF13831.1 KND90630.1 - 0.074 12.3 0.8 0.18 11.1 0.6 1.7 1 0 0 1 1 1 0 PHD-finger SET PF00856.23 KND90631.1 - 0.0014 18.9 0.0 0.87 9.8 0.0 3.0 2 1 1 3 3 3 2 SET domain MFS_1 PF07690.11 KND90632.1 - 3.3e-35 121.4 28.5 2.7e-34 118.4 20.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KND90632.1 - 0.0051 17.1 0.9 0.021 15.2 0.3 2.3 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Doppel PF11466.3 KND90633.1 - 0.84 9.2 3.7 2.1 7.9 0.6 3.0 2 0 0 2 2 2 0 Prion-like protein Doppel ATP_bind_3 PF01171.15 KND90636.1 - 1.1e-19 70.6 0.0 1.6e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 KND90636.1 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KND90636.1 - 0.0037 15.8 0.0 0.0074 14.8 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 KND90636.1 - 0.0086 15.4 0.7 0.0086 15.4 0.5 3.1 4 0 0 4 4 4 1 RecR protein zf-UBR PF02207.15 KND90636.1 - 1.7 8.3 7.8 4.4 7.0 0.3 2.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) FAD_binding_3 PF01494.14 KND90638.1 - 2.3e-17 63.1 2.6 2.3e-06 26.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KND90638.1 - 1.2e-05 25.2 0.1 2.8e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND90638.1 - 0.00012 21.1 1.0 0.00034 19.6 0.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KND90638.1 - 0.061 12.4 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 KND90638.1 - 0.16 12.3 0.0 0.54 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L7Ae PF01248.21 KND90639.1 - 2.7e-21 74.8 0.8 4.4e-21 74.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NTF2 PF02136.15 KND90640.1 - 1e-28 100.1 0.2 1.3e-28 99.7 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain ATG13 PF10033.4 KND90641.1 - 2e-67 227.0 0.0 3.2e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 ENTH PF01417.15 KND90642.1 - 7.5e-47 158.2 0.0 1.2e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 KND90642.1 - 0.0037 16.7 0.5 0.0037 16.7 0.4 3.0 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF4264 PF14084.1 KND90642.1 - 0.048 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) VHS PF00790.14 KND90642.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 VHS domain ANTH PF07651.11 KND90642.1 - 0.097 11.3 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 ANTH domain CK_II_beta PF01214.13 KND90644.1 - 2e-74 249.1 0.2 6e-74 247.5 0.1 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KND90644.1 - 0.0073 16.9 6.6 0.012 16.2 4.5 1.4 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.6 KND90644.1 - 0.17 9.7 1.2 0.2 9.4 0.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.9 KND90644.1 - 0.24 10.8 1.6 0.34 10.3 1.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 KND90644.1 - 0.35 10.3 5.9 0.48 9.9 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_L23eN PF03939.8 KND90645.1 - 0.014 15.4 1.0 0.026 14.5 0.7 1.5 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain Peptidase_M24 PF00557.19 KND90647.1 - 1.6e-25 89.9 0.1 1.9e-14 53.7 0.0 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 Herpes_US9 PF06072.6 KND90647.1 - 0.13 12.1 1.2 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 HgmA PF04209.8 KND90650.1 - 1.7e-171 570.3 0.0 1.9e-171 570.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PH PF00169.24 KND90651.1 - 0.00028 21.0 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 KND90651.1 - 0.0019 17.7 0.6 0.0031 17.0 0.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain eRF1_3 PF03465.10 KND90651.1 - 0.085 13.1 0.0 0.34 11.2 0.0 2.0 1 1 1 2 2 2 0 eRF1 domain 3 Fib_alpha PF08702.5 KND90651.1 - 0.27 11.3 0.9 0.53 10.4 0.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Arrestin_N PF00339.24 KND90652.1 - 1.8e-18 66.8 0.0 3.9e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KND90652.1 - 1.3e-16 60.9 0.0 4.3e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KND90652.1 - 0.0022 17.5 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like PAS_9 PF13426.1 KND90653.1 - 7.8e-13 48.7 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KND90653.1 - 0.0022 17.7 0.0 0.005 16.6 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 KND90653.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 KND90653.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold Fapy_DNA_glyco PF01149.19 KND90654.1 - 2.5e-27 95.5 0.0 4.2e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KND90654.1 - 5.7e-20 70.8 0.0 1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KND90654.1 - 0.0099 14.4 0.0 0.019 13.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Peptidase_S10 PF00450.17 KND90655.1 - 3.4e-77 260.3 0.6 5.6e-77 259.6 0.4 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase zf-Nse PF11789.3 KND90656.1 - 3.9e-23 80.7 0.3 7.2e-23 79.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KND90656.1 - 0.00021 20.7 0.9 0.00032 20.1 0.6 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 KND90656.1 - 0.0012 18.4 0.6 0.0025 17.5 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KND90656.1 - 0.016 15.0 0.8 0.03 14.1 0.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 KND90656.1 - 0.048 13.4 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Mss51 PF13824.1 KND90656.1 - 0.1 12.4 0.2 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-rbx1 PF12678.2 KND90656.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger Herpes_UL25 PF01499.11 KND90656.1 - 0.53 8.5 9.8 0.76 8.0 6.4 1.5 2 0 0 2 2 2 0 Herpesvirus UL25 family CorA PF01544.13 KND90656.1 - 5.6 5.9 5.8 0.45 9.4 0.6 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DHBP_synthase PF00926.14 KND90657.1 - 1e-69 233.6 0.0 4.7e-69 231.5 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 KND90658.1 - 9.7e-22 77.3 0.0 1.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND90658.1 - 9.2e-17 61.3 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90658.1 - 1.4e-16 60.4 0.0 1.7e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND90658.1 - 3.7e-15 56.4 0.0 5.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND90658.1 - 3.2e-13 49.9 0.0 5.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND90658.1 - 2.1e-08 34.1 0.0 1.3e-07 31.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90658.1 - 3.5e-07 30.5 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND90658.1 - 1.9e-05 23.9 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KND90658.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KND90658.1 - 0.0023 17.3 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 KND90658.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KND90658.1 - 0.0037 16.3 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 KND90658.1 - 0.031 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) WD40 PF00400.27 KND90659.1 - 5.6e-21 73.5 13.0 3.6e-06 26.6 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KND90659.1 - 0.0027 17.4 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KND90659.1 - 0.0072 14.2 0.0 0.011 13.5 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 KND90659.1 - 0.042 12.1 0.0 0.069 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain EF_assoc_2 PF08356.7 KND90660.1 - 6.8e-34 115.4 0.0 1.4e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 KND90660.1 - 1.5e-33 115.8 0.0 1.9e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KND90660.1 - 8.8e-29 98.6 0.0 2.6e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 KND90660.1 - 1.7e-22 79.5 0.0 2.9e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KND90660.1 - 6.8e-09 35.7 0.0 0.00076 19.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 KND90660.1 - 1e-07 31.9 4.6 0.00091 19.3 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KND90660.1 - 3.2e-07 29.1 9.1 0.003 16.7 0.2 3.2 3 0 0 3 3 3 2 EF hand Dynamin_N PF00350.18 KND90660.1 - 4e-07 29.9 0.1 0.0017 18.1 0.1 3.1 2 1 1 3 3 3 2 Dynamin family EF-hand_6 PF13405.1 KND90660.1 - 1.4e-05 24.5 7.0 0.033 14.0 0.5 3.0 3 0 0 3 3 2 2 EF-hand domain AAA_16 PF13191.1 KND90660.1 - 1.7e-05 24.9 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND90660.1 - 2e-05 24.7 0.0 0.02 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND90660.1 - 5.6e-05 22.5 0.0 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KND90660.1 - 0.00044 20.2 0.0 0.67 9.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain GTP_EFTU PF00009.22 KND90660.1 - 0.00083 18.8 0.0 2.3 7.6 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.1 KND90660.1 - 0.0058 15.9 11.8 0.049 12.9 1.6 3.2 3 0 0 3 3 3 2 EF hand ABC_tran PF00005.22 KND90660.1 - 0.0093 16.2 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 KND90660.1 - 0.012 15.5 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KND90660.1 - 0.016 14.9 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KND90660.1 - 0.024 13.8 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF815 PF05673.8 KND90660.1 - 0.055 12.3 0.0 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KND90660.1 - 0.058 13.5 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase EF-hand_10 PF14788.1 KND90660.1 - 0.061 12.9 1.1 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 EF hand AAA_25 PF13481.1 KND90660.1 - 0.088 12.1 0.0 5.3 6.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 KND90660.1 - 0.12 11.9 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 KND90660.1 - 0.33 10.6 5.6 8.4 6.1 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair Cyclin_N PF00134.18 KND90661.1 - 9.4e-14 51.0 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KND90661.1 - 8.4e-11 42.4 0.0 1.9e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin DUF3984 PF13136.1 KND90661.1 - 0.055 12.6 4.9 0.088 12.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Mating_C PF12737.2 KND90661.1 - 2.6 6.8 17.7 2.7 6.7 6.8 2.3 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 E1-E2_ATPase PF00122.15 KND90662.1 - 2e-50 170.9 0.2 5.7e-50 169.4 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND90662.1 - 1.2e-35 123.9 0.7 5.4e-35 121.7 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KND90662.1 - 2e-17 63.0 0.1 8.1e-10 38.7 0.0 3.8 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 KND90662.1 - 1.3e-15 58.0 0.0 3.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND90662.1 - 2.6e-07 30.4 0.0 7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PAP1 PF08601.5 KND90663.1 - 5.1e-47 161.2 15.5 5.1e-47 161.2 10.8 2.4 1 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KND90663.1 - 2.2e-08 33.9 12.9 5e-08 32.7 8.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor Tropomyosin PF00261.15 KND90663.1 - 0.00094 18.3 8.5 0.0017 17.4 5.9 1.3 1 0 0 1 1 1 1 Tropomyosin bZIP_2 PF07716.10 KND90663.1 - 0.0015 18.3 13.2 0.0053 16.5 9.1 1.9 1 1 0 1 1 1 1 Basic region leucine zipper ERM PF00769.14 KND90663.1 - 0.0031 17.1 4.1 0.0031 17.1 2.9 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family bZIP_Maf PF03131.12 KND90663.1 - 0.0083 16.4 11.2 0.019 15.2 7.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor SlyX PF04102.7 KND90663.1 - 0.012 15.9 3.1 0.031 14.6 2.1 1.7 1 0 0 1 1 1 0 SlyX FlaC_arch PF05377.6 KND90663.1 - 0.034 14.0 0.8 0.066 13.1 0.6 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KND90663.1 - 0.051 13.1 2.6 0.093 12.3 1.8 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KND90663.1 - 0.098 13.0 2.5 0.27 11.6 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF812 PF05667.6 KND90663.1 - 0.12 10.8 8.4 0.0083 14.6 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) APG6 PF04111.7 KND90663.1 - 0.13 11.2 3.6 0.26 10.3 2.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Adeno_PIX PF03955.9 KND90663.1 - 0.14 12.6 4.6 0.087 13.3 1.0 2.3 2 0 0 2 2 1 0 Adenovirus hexon-associated protein (IX) DOG1 PF14144.1 KND90663.1 - 0.19 11.8 0.9 0.4 10.7 0.6 1.6 1 0 0 1 1 1 0 Seed dormancy control DUF904 PF06005.7 KND90663.1 - 0.26 11.5 5.5 0.62 10.4 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Herpes_UL6 PF01763.11 KND90663.1 - 0.36 8.9 3.8 0.57 8.2 2.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 KND90663.1 - 1.1 7.0 2.1 1.6 6.5 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 KND90663.1 - 1.4 7.6 11.3 1.3 7.7 4.1 2.7 2 2 0 2 2 2 0 Intra-flagellar transport protein 57 Pkinase PF00069.20 KND90664.1 - 6.9e-43 146.6 0.0 2.2e-42 145.0 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND90664.1 - 5.2e-21 74.8 0.0 7.2e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND90664.1 - 0.00096 18.9 2.0 0.0015 18.3 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND90664.1 - 0.0033 16.4 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND90664.1 - 0.01 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAP_N PF01213.14 KND90664.1 - 3.4 6.8 6.9 5.4 6.2 4.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KND90664.1 - 4.5 6.5 8.7 1.8 7.8 4.3 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Surp PF01805.15 KND90665.1 - 5.2e-13 48.4 0.0 1.2e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Surp module Fungal_trans PF04082.13 KND90666.1 - 1.2e-06 27.6 5.8 1.5e-06 27.3 1.3 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KND90666.1 - 4.9e-05 23.4 11.7 0.0019 18.4 0.1 4.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND90666.1 - 6.4e-05 23.0 1.8 6.4e-05 23.0 1.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND90666.1 - 0.075 13.4 0.1 0.075 13.4 0.1 4.7 3 1 0 3 3 3 0 C2H2-type zinc finger Methyltransf_16 PF10294.4 KND90667.1 - 2.3e-09 36.9 0.0 5.2e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase PhyH PF05721.8 KND90667.1 - 1.1e-08 35.3 0.0 5e-08 33.2 0.0 2.0 2 2 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Copper-fist PF00649.13 KND90668.1 - 6.3e-19 66.8 0.7 1.4e-18 65.7 0.5 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain DUF1237 PF06824.6 KND90669.1 - 9.4e-160 531.8 0.1 2.1e-158 527.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1237) HECT PF00632.20 KND90670.1 - 8.8e-79 264.9 0.0 1.8e-78 263.9 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KND90670.1 - 1.2e-05 24.4 0.9 4.1e-05 22.8 0.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Acetyltransf_2 PF00797.12 KND90670.1 - 0.019 14.5 0.2 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 N-acetyltransferase RXT2_N PF08595.6 KND90671.1 - 2.3e-37 128.0 0.0 8e-37 126.3 0.0 2.0 2 0 0 2 2 2 1 RXT2-like, N-terminal Glyco_hydro_3 PF00933.16 KND90672.1 - 4.6e-54 183.4 0.0 6.5e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KND90672.1 - 0.0019 18.1 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Fe_hyd_SSU PF02256.12 KND90672.1 - 0.041 13.8 0.1 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Iron hydrogenase small subunit PNP_UDP_1 PF01048.15 KND90672.1 - 0.085 11.8 0.0 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Phosphorylase superfamily Hexokinase_2 PF03727.11 KND90673.1 - 4e-35 121.1 0.0 1.6e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KND90673.1 - 1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ESCRT-II PF05871.7 KND90674.1 - 1.5e-48 164.2 0.0 1.9e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PTCB-BRCT PF12738.2 KND90675.1 - 5.5e-27 93.4 0.0 1.7e-19 69.4 0.1 4.0 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 KND90675.1 - 2.1e-23 82.2 0.0 1.6e-08 34.5 0.0 6.3 6 1 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain NIR_SIR PF01077.17 KND90676.1 - 7.7e-31 106.5 0.0 1.3e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KND90676.1 - 1.6e-23 83.6 0.0 3.1e-23 82.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND90676.1 - 1.1e-15 57.7 5.2 2.8e-15 56.4 0.7 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KND90676.1 - 2.6e-13 49.5 0.0 5.5e-12 45.3 0.0 2.7 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 KND90676.1 - 3.3e-13 49.4 5.8 5.3e-11 42.4 3.7 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 KND90676.1 - 3.6e-11 42.5 0.0 7.8e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 KND90676.1 - 7.3e-11 41.5 0.1 2.3e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KND90676.1 - 1.9e-06 28.0 0.0 1.5e-05 25.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND90676.1 - 0.003 16.5 4.8 0.48 9.2 0.0 4.4 4 1 1 5 5 5 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND90676.1 - 0.0068 16.1 1.0 8.9 6.0 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KND90676.1 - 0.037 14.2 0.2 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KND90676.1 - 0.074 11.8 1.2 4.6 5.9 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain Amino_oxidase PF01593.19 KND90676.1 - 0.11 11.5 0.3 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 KND90676.1 - 0.18 10.6 0.0 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amidohydro_4 PF13147.1 KND90677.1 - 5.9e-15 56.0 0.7 1.3e-06 28.6 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KND90677.1 - 3.5e-07 29.7 0.0 5.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KND90677.1 - 8.9e-06 25.5 0.2 7.5e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND90677.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase NDT80_PhoG PF05224.7 KND90678.1 - 3e-36 125.1 0.0 4.8e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2685 PF10886.3 KND90679.1 - 0.11 12.5 0.2 2 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2685) SRR1 PF07985.7 KND90679.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 SRR1 Glucosamine_iso PF01182.15 KND90680.1 - 8.3e-26 90.9 0.0 1.3e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Seipin PF06775.9 KND90681.1 - 3.2e-48 163.8 0.3 4e-48 163.5 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.10 KND90682.1 - 6e-114 380.8 0.0 1.1e-113 379.9 0.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KND90682.1 - 3.7e-46 156.4 1.5 1.1e-45 154.8 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Na_Ca_ex PF01699.19 KND90683.1 - 1.3e-46 157.6 38.2 1.5e-25 89.4 8.8 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_81 PF03639.8 KND90684.1 - 1.4e-199 664.5 3.9 1.8e-199 664.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Stn1 PF10451.4 KND90685.1 - 1.2e-15 57.0 0.0 1.5e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KND90685.1 - 7.1e-06 25.7 0.3 1.3e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Atg14 PF10186.4 KND90685.1 - 0.58 9.0 2.5 0.74 8.6 1.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DnaJ PF00226.26 KND90686.1 - 1.8e-23 82.0 1.6 4.6e-23 80.7 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain SIMPL PF04402.9 KND90686.1 - 0.0068 16.2 0.9 0.018 14.9 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF541) dCMP_cyt_deam_1 PF00383.17 KND90687.1 - 3.3e-11 42.7 0.0 4.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FeThRed_B PF02943.10 KND90690.1 - 9.1 6.0 8.4 0.27 10.9 0.5 2.0 1 1 1 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain COX15-CtaA PF02628.10 KND90691.1 - 4.6e-96 321.2 9.8 5.7e-96 320.9 6.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.8 KND90692.1 - 1.6e-164 548.9 77.4 1.6e-164 548.9 53.7 3.7 1 1 1 2 2 2 1 Utp14 protein DUF4604 PF15377.1 KND90693.1 - 1.1e-29 103.6 18.4 1.3e-29 103.4 12.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2239 PF09998.4 KND90693.1 - 0.019 14.5 1.2 0.031 13.8 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) IER PF05760.7 KND90693.1 - 0.071 13.0 9.7 0.083 12.8 6.7 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) MTBP_C PF14920.1 KND90693.1 - 3.2 7.1 7.8 0.57 9.6 2.6 1.7 1 1 1 2 2 2 0 MDM2-binding DUF2427 PF10348.4 KND90694.1 - 1.9e-06 27.3 2.8 1.9e-06 27.3 2.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KND90694.1 - 0.0044 16.8 9.3 0.0044 16.8 6.4 1.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 ISK_Channel PF02060.10 KND90694.1 - 0.057 13.0 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Tetraspannin PF00335.15 KND90694.1 - 0.42 9.8 7.8 0.054 12.7 2.1 1.8 1 1 1 2 2 2 0 Tetraspanin family E1-E2_ATPase PF00122.15 KND90695.1 - 2.3e-51 174.0 0.4 4.2e-51 173.1 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND90695.1 - 4.5e-35 120.8 5.6 4.5e-35 120.8 3.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND90695.1 - 4.8e-30 105.5 0.0 6.1e-29 101.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND90695.1 - 9.3e-18 63.9 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KND90695.1 - 2.5e-15 57.1 0.3 2.1e-14 54.1 0.1 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND90695.1 - 1.1e-13 50.3 0.0 7.7e-13 47.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KND90695.1 - 0.0039 16.8 0.2 0.0072 15.9 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 KND90695.1 - 0.27 11.6 6.2 0.067 13.5 0.5 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF2207 PF09972.4 KND90695.1 - 1.4 7.4 5.0 1.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1469 PF07332.6 KND90695.1 - 3.1 7.5 15.6 3 7.5 0.8 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) GFO_IDH_MocA PF01408.17 KND90696.1 - 1.9e-25 89.7 0.6 3.8e-25 88.7 0.4 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KND90696.1 - 9.4e-07 28.6 0.0 2.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 KND90696.1 - 0.0055 16.5 0.1 0.021 14.6 0.1 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DSRB PF10781.4 KND90696.1 - 0.14 11.6 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Dextransucrase DSRB Fungal_trans_2 PF11951.3 KND90697.1 - 1.6e-10 40.1 2.7 2.8e-10 39.3 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KND90699.1 - 2.2e-11 43.0 1.8 2.5e-11 42.8 1.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND90699.1 - 0.0061 15.3 7.4 0.017 13.8 5.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF373 PF04123.8 KND90699.1 - 0.026 13.5 0.1 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF308 PF03729.8 KND90699.1 - 2.1 8.3 5.0 3.2 7.8 3.0 1.6 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) SLAC1 PF03595.12 KND90700.1 - 8.6e-47 159.3 24.6 9.5e-47 159.2 17.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Mem_trans PF03547.13 KND90700.1 - 1.4 7.1 9.6 0.76 8.0 5.1 1.6 1 1 1 2 2 2 0 Membrane transport protein DUF3165 PF11364.3 KND90700.1 - 7.5 6.7 9.4 1.1 9.4 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3165) APH PF01636.18 KND90701.1 - 2.9e-13 50.1 0.1 3.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND90701.1 - 0.00042 19.9 0.0 0.00046 19.8 0.0 1.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND90701.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KND90701.1 - 0.056 12.5 0.0 0.07 12.2 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase Cupin_1 PF00190.17 KND90702.1 - 1.9e-28 98.7 0.0 5.3e-15 55.1 0.0 2.4 2 1 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KND90702.1 - 1.4e-23 82.1 2.7 3.5e-11 42.4 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.7 KND90702.1 - 3e-07 29.7 0.1 0.011 15.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KND90702.1 - 7.5e-05 22.4 0.3 0.15 11.7 0.2 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KND90702.1 - 0.00029 20.4 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 2 Cupin Amidinotransf PF02274.12 KND90703.1 - 1.2e-09 37.6 0.0 8.1e-05 21.8 0.0 3.0 2 1 0 2 2 2 2 Amidinotransferase DUF1996 PF09362.5 KND90704.1 - 1.7e-67 227.5 0.1 2e-67 227.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Clc-like PF07062.7 KND90706.1 - 0.3 10.2 0.1 0.3 10.2 0.0 2.6 3 0 0 3 3 3 0 Clc-like DUF2042 PF09743.4 KND90707.1 - 0.049 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Methyltransf_2 PF00891.13 KND90708.1 - 9.4e-22 77.3 0.0 1.3e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Aldo_ket_red PF00248.16 KND90709.1 - 7.1e-44 149.7 0.0 9.2e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 KND90710.1 - 3.9e-75 253.1 17.8 1.8e-74 250.9 12.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter PRKCSH-like PF12999.2 KND90710.1 - 2.1e-42 144.6 2.7 1.3e-24 86.7 0.3 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KND90710.1 - 6.7e-25 87.3 0.0 1.5e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MFS_1 PF07690.11 KND90710.1 - 3.1e-21 75.5 64.3 4.4e-19 68.4 29.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PRKCSH PF07915.8 KND90710.1 - 2.3e-05 25.1 0.1 4.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein FadA PF09403.5 KND90710.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.8 3 0 0 3 3 3 0 Adhesion protein FadA V_ATPase_I PF01496.14 KND90710.1 - 0.4 8.4 4.0 0.74 7.5 2.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apt1 PF10351.4 KND90710.1 - 2.1 7.0 3.4 3.5 6.3 2.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAT PF02259.18 KND90711.1 - 5.7e-129 430.1 7.6 1.4e-128 428.8 5.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KND90711.1 - 2.2e-62 210.6 0.2 3.8e-62 209.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KND90711.1 - 7.2e-61 204.7 1.5 1.3e-59 200.6 0.3 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KND90711.1 - 1.7e-43 146.7 0.3 1.7e-43 146.7 0.2 3.4 4 0 0 4 4 4 1 Rapamycin binding domain FATC PF02260.15 KND90711.1 - 4.9e-14 51.4 0.1 1.2e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 KND90711.1 - 1.7e-13 50.6 6.8 0.0074 16.5 0.1 8.2 5 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KND90711.1 - 7.9e-12 44.2 10.1 0.015 15.2 0.0 9.2 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 KND90711.1 - 1.4e-08 34.9 11.3 0.00013 22.3 0.0 9.2 10 2 2 12 12 12 2 HEAT-like repeat Baculo_PEP_C PF04513.7 KND90711.1 - 0.038 13.8 2.3 0.093 12.5 0.3 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_2 PF07719.12 KND90711.1 - 8.8 6.5 8.9 99 3.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NMT1 PF09084.6 KND90712.1 - 8.2e-76 254.3 0.0 1e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KND90712.1 - 3.4e-10 39.7 0.2 0.0078 15.6 0.0 3.5 2 1 2 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.2 KND90712.1 - 0.047 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Glycoamylase PF10091.4 KND90713.1 - 0.039 13.0 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative glucoamylase Fungal_trans PF04082.13 KND90714.1 - 6e-15 54.8 0.0 4.9e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90714.1 - 1.1e-05 25.2 9.6 1.9e-05 24.4 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND90715.1 - 5.6e-31 107.3 0.0 3.6e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF969 PF06149.7 KND90715.1 - 0.062 12.5 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Acyl-CoA_dh_1 PF00441.19 KND90716.1 - 6.9e-32 110.6 4.8 6.9e-32 110.6 3.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND90716.1 - 1.9e-19 70.3 1.0 5.9e-19 68.7 0.7 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KND90716.1 - 9.5e-16 57.0 0.4 2.5e-15 55.7 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KND90716.1 - 1.5e-12 47.9 6.2 1.5e-12 47.9 4.3 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DHDPS PF00701.17 KND90717.1 - 2.3e-39 134.7 0.0 2.9e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 KND90718.1 - 4.5e-32 111.1 27.8 4.5e-32 111.1 19.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 KND90719.1 - 2e-63 213.7 0.2 2.9e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND90719.1 - 6.1e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KND90719.1 - 7.1e-06 25.0 0.2 2.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KND90719.1 - 0.0001 22.1 0.2 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family D-ser_dehydrat PF14031.1 KND90720.1 - 1.6e-20 73.1 0.0 3.5e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KND90720.1 - 4e-15 55.9 2.2 5.3e-15 55.5 1.5 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Glyco_hydro_1 PF00232.13 KND90722.1 - 7.2e-151 502.4 0.0 8.4e-151 502.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KND90722.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Sugar_tr PF00083.19 KND90723.1 - 5.6e-72 242.7 24.8 6.9e-72 242.4 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND90723.1 - 1.9e-23 82.7 28.0 1.3e-20 73.4 10.4 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily DEAD PF00270.24 KND90724.1 - 9.9e-41 139.0 0.1 2.4e-40 137.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND90724.1 - 4e-22 77.8 0.0 9e-12 44.6 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KND90724.1 - 5.1e-05 23.1 0.5 0.00023 21.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 KND90724.1 - 0.0017 16.5 1.1 0.002 16.2 0.8 1.1 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.7 KND90724.1 - 0.0081 15.3 10.6 0.016 14.3 7.4 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Glyco_hydro_16 PF00722.16 KND90726.1 - 6.6e-43 146.1 1.9 1.4e-42 145.1 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SWI-SNF_Ssr4 PF08549.5 KND90726.1 - 0.16 10.2 0.0 0.16 10.2 0.0 1.8 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Sod_Cu PF00080.15 KND90727.1 - 5.6e-13 49.2 0.0 9.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KND90727.1 - 3.3e-10 39.9 0.0 6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_11 PF13414.1 KND90728.1 - 2.1e-16 59.3 4.8 2e-11 43.3 0.1 3.3 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 KND90728.1 - 3.9e-16 57.8 4.7 1.3e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND90728.1 - 2.9e-15 54.8 3.7 1.7e-06 27.4 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KND90728.1 - 5.3e-11 41.4 0.7 3.1e-05 23.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND90728.1 - 5.7e-09 35.7 0.8 3.4e-05 23.6 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND90728.1 - 6.6e-09 34.9 0.3 4.8e-07 29.1 0.0 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KND90728.1 - 3.5e-08 33.3 0.1 0.13 12.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND90728.1 - 8.7e-07 28.6 0.5 0.0045 17.0 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND90728.1 - 3.1e-05 24.5 0.6 0.0013 19.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KND90728.1 - 6.3e-05 22.7 0.5 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND90728.1 - 0.00077 19.8 2.0 0.021 15.4 0.0 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.19 KND90728.1 - 0.0034 17.0 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Apc3 PF12895.2 KND90728.1 - 0.048 13.8 1.1 0.09 12.9 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KND90728.1 - 0.069 13.6 0.2 35 5.2 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND90728.1 - 0.11 12.4 0.0 5.4 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.16 KND90729.1 - 6.5e-88 294.4 0.0 9.9e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 KND90730.1 - 2.1e-23 81.8 5.8 3.7e-23 81.0 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KND90730.1 - 6.3e-19 67.6 0.3 4.8e-17 61.6 0.0 3.0 3 1 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KND90730.1 - 9e-14 51.2 18.9 9e-14 51.2 13.1 1.7 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 KND90730.1 - 0.00016 21.2 2.1 0.16 11.7 0.7 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Malate_DH PF12434.3 KND90730.1 - 0.019 14.6 1.3 0.042 13.5 0.9 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme NMDAR2_C PF10565.4 KND90730.1 - 0.024 13.3 1.8 0.032 12.9 1.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus zf-CHY PF05495.7 KND90730.1 - 0.27 11.4 6.1 2.5 8.3 0.4 2.4 2 0 0 2 2 2 0 CHY zinc finger EAP30 PF04157.11 KND90731.1 - 5.4e-63 212.1 0.0 9.2e-63 211.3 0.0 1.3 1 1 0 1 1 1 1 EAP30/Vps36 family Serglycin PF04360.7 KND90731.1 - 0.019 14.6 0.1 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Serglycin Uricase PF01014.13 KND90735.1 - 5e-82 272.8 2.2 2.5e-45 153.9 0.6 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 KND90736.1 - 2.2e-39 134.4 0.0 3.1e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Arrestin_C PF02752.17 KND90738.1 - 3.8e-17 62.6 2.6 1e-16 61.2 0.0 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KND90738.1 - 1e-07 31.8 0.0 0.00056 19.7 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Snf7 PF03357.16 KND90739.1 - 3.8e-35 120.7 18.7 3.8e-35 120.7 13.0 1.3 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KND90739.1 - 0.0081 14.0 2.7 0.0099 13.7 1.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CaMBD PF02888.11 KND90739.1 - 0.014 15.1 2.7 0.014 15.1 1.9 2.2 1 1 1 2 2 2 0 Calmodulin binding domain Ist1 PF03398.9 KND90739.1 - 0.069 12.5 6.0 0.11 11.8 4.1 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.7 KND90739.1 - 0.82 8.9 15.4 1.8 7.8 3.5 2.2 1 1 1 2 2 2 0 PspA/IM30 family DSBA PF01323.15 KND90739.1 - 1.5 8.3 6.1 2.7 7.4 4.2 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain PP2C PF00481.16 KND90740.1 - 1.2e-60 205.0 0.1 2e-49 168.3 0.1 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C A_deaminase PF00962.17 KND90741.1 - 2.4e-28 99.0 0.0 2.8e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_N PF00350.18 KND90742.1 - 4.4e-19 68.9 0.2 9.5e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KND90742.1 - 2.3e-10 40.4 0.1 1.1e-09 38.2 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND90742.1 - 3.5e-08 33.1 1.1 2.1e-07 30.5 0.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PMEI PF04043.10 KND90742.1 - 0.0074 16.2 0.1 0.075 12.9 0.0 2.5 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor AAA_29 PF13555.1 KND90742.1 - 0.032 13.7 0.0 0.098 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KND90742.1 - 0.069 13.6 0.1 0.8 10.2 0.1 2.7 1 1 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 KND90742.1 - 0.084 13.1 0.1 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KND90742.1 - 0.098 12.1 0.0 0.28 10.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zn_clus PF00172.13 KND90744.1 - 2.9e-07 30.2 11.9 5.6e-07 29.3 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KND90745.1 - 2.2e-109 366.0 22.6 2.2e-109 366.0 15.7 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KND90745.1 - 2.6e-28 98.7 49.3 1.6e-23 83.0 19.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KND90745.1 - 0.03 12.4 4.7 0.067 11.3 1.0 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector ALMT PF11744.3 KND90745.1 - 0.15 10.6 0.6 0.28 9.7 0.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-3CxxC PF13695.1 KND90746.1 - 3.7e-09 36.6 0.1 5.6e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding domain Sporozoite_P67 PF05642.6 KND90747.1 - 0.049 11.4 7.8 0.048 11.5 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cu_bind_like PF02298.12 KND90747.1 - 0.078 12.7 0.1 0.33 10.7 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain RAP1 PF07218.6 KND90747.1 - 6.3 4.7 6.9 8.4 4.3 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NB-ARC PF00931.17 KND90749.1 - 1.9e-08 33.5 0.0 2.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KND90749.1 - 9.7e-07 28.9 0.0 4.5e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KND90749.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KND90749.1 - 4.6e-06 26.8 0.0 8.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KND90749.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TPR_12 PF13424.1 KND90749.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 KND90749.1 - 0.0031 17.3 0.0 1.2 9.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat SRP54 PF00448.17 KND90749.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 KND90749.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Sda PF08970.5 KND90750.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation inhibitor A ATP13 PF12921.2 KND90751.1 - 4.6e-17 61.5 0.0 1.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression Myb_DNA-binding PF00249.26 KND90753.1 - 2.4e-14 53.0 3.0 1.1e-07 31.7 0.7 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND90753.1 - 1.7e-12 47.2 0.6 7.5e-06 25.9 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 KND90753.1 - 0.069 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_2 PF08914.6 KND90753.1 - 0.085 12.6 0.3 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 Rap1 Myb domain MADF_DNA_bdg PF10545.4 KND90753.1 - 0.19 11.9 1.3 21 5.3 0.1 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PAT1 PF09770.4 KND90753.1 - 0.81 7.8 21.1 0.8 7.8 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myb_DNA-binding PF00249.26 KND90754.1 - 0.043 13.8 0.8 0.57 10.2 0.4 2.6 2 1 0 2 2 2 0 Myb-like DNA-binding domain YEATS PF03366.11 KND90755.1 - 2.8e-23 81.4 0.3 5.4e-23 80.5 0.2 1.5 1 0 0 1 1 1 1 YEATS family SNARE_assoc PF09335.6 KND90755.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein Ran_BP1 PF00638.13 KND90756.1 - 6.6e-48 161.7 3.4 1.3e-47 160.8 2.4 1.5 1 0 0 1 1 1 1 RanBP1 domain TMEM247 PF15444.1 KND90756.1 - 1.2 8.9 6.8 1.8 8.3 4.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Phosducin PF02114.11 KND90758.1 - 1.2e-13 50.3 0.0 9.6e-12 44.1 0.0 2.2 1 1 0 1 1 1 1 Phosducin OHCU_decarbox PF09349.5 KND90759.1 - 4.1e-39 134.4 0.0 6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.6 KND90761.1 - 1.4e-31 108.0 1.6 2.9e-31 107.0 1.1 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KND90761.1 - 3.7e-15 55.1 0.1 8.9e-05 22.2 0.0 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat zf-Nse PF11789.3 KND90761.1 - 0.095 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 KND90761.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain VID27 PF08553.5 KND90761.1 - 0.16 10.1 0.0 0.24 9.5 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-RING_5 PF14634.1 KND90762.1 - 0.00044 19.9 1.5 0.0048 16.5 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND90762.1 - 0.019 14.9 1.0 0.019 14.9 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND90762.1 - 0.051 13.2 2.1 0.18 11.4 1.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND90762.1 - 0.21 11.4 2.3 0.49 10.3 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING adh_short PF00106.20 KND90764.1 - 1.3e-29 103.2 4.2 2e-29 102.6 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND90764.1 - 1.9e-25 90.0 0.4 2.3e-25 89.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND90764.1 - 3.9e-15 55.9 3.0 9.8e-15 54.6 2.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND90764.1 - 1.1e-07 31.5 1.9 5.4e-07 29.2 1.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KND90764.1 - 7.1e-06 25.1 0.3 1.6e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 KND90764.1 - 0.0047 16.7 0.2 0.011 15.5 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KND90764.1 - 0.062 11.9 0.2 0.089 11.4 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_3 PF13738.1 KND90765.1 - 3.6e-23 82.6 0.0 5.5e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KND90765.1 - 3.3e-14 51.9 0.1 4.6e-13 48.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND90765.1 - 1.6e-11 44.0 0.0 2.1e-08 34.0 0.0 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KND90765.1 - 2.7e-10 39.6 0.0 1.1e-07 31.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KND90765.1 - 1.3e-05 25.0 0.3 0.0026 17.5 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KND90765.1 - 0.00013 20.9 0.0 0.003 16.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KND90765.1 - 0.00071 19.6 0.0 0.019 15.0 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KND90765.1 - 0.002 17.2 0.0 0.089 11.8 0.0 2.9 3 0 0 3 3 3 1 Thi4 family Semialdhyde_dh PF01118.19 KND90765.1 - 0.0055 17.0 0.0 0.035 14.4 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KND90765.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KND90765.1 - 0.11 11.4 0.0 6.1 5.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KND90765.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.16 KND90766.1 - 2e-108 362.7 48.4 2.5e-108 362.4 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND90766.1 - 6.8e-27 94.0 53.3 8.2e-27 93.8 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 KND90766.1 - 0.25 9.7 0.0 0.35 9.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Fungal_trans_2 PF11951.3 KND90767.1 - 6.9e-53 179.6 0.4 8.7e-53 179.2 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLDc_2 PF13091.1 KND90767.1 - 0.01 15.5 0.1 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain adh_short PF00106.20 KND90768.1 - 4.1e-24 85.3 3.4 5.4e-24 84.9 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND90768.1 - 6.2e-22 78.5 0.4 7e-22 78.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND90768.1 - 1.9e-09 37.4 1.0 2.6e-09 36.9 0.7 1.2 1 0 0 1 1 1 1 KR domain GCIP PF13324.1 KND90769.1 - 0.0011 18.2 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting LNP1 PF15419.1 KND90770.1 - 0.089 12.8 11.7 0.57 10.2 0.7 2.5 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Sugar_tr PF00083.19 KND90771.1 - 2.3e-114 382.4 27.1 2.8e-114 382.2 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND90771.1 - 3.3e-26 91.8 51.5 1e-22 80.3 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND90771.1 - 5.7e-09 34.8 27.2 0.00012 20.6 8.2 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein DUF791 PF05631.9 KND90771.1 - 0.002 16.8 1.8 0.0043 15.8 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Glucan_synthase PF02364.10 KND90773.1 - 0 1452.8 0.0 0 1451.9 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KND90773.1 - 1.2e-39 134.8 0.4 3.2e-39 133.4 0.3 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 KND90774.1 - 1.4e-33 116.3 0.0 2.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2_jaz PF12171.3 KND90775.1 - 5.9e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND90775.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DASH_Dam1 PF08653.5 KND90776.1 - 8e-28 95.9 1.3 1.1e-27 95.5 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Rhomboid PF01694.17 KND90777.1 - 7.6e-15 55.2 11.1 7.6e-15 55.2 7.7 1.8 2 0 0 2 2 2 1 Rhomboid family Aconitase PF00330.15 KND90778.1 - 8.9e-174 578.3 0.0 3.4e-173 576.4 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KND90778.1 - 5.8e-45 152.6 0.0 9.6e-45 151.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Mog1 PF04603.7 KND90779.1 - 4.1e-10 39.7 0.0 6.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.4 KND90781.1 - 3.1e-53 179.6 4.7 5.2e-53 178.9 3.3 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 KND90781.1 - 0.0016 18.6 0.1 0.0075 16.5 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box Peptidase_MA_2 PF13485.1 KND90781.1 - 0.062 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Zn-ribbon_8 PF09723.5 KND90781.1 - 0.09 12.7 1.7 0.23 11.4 1.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain CRAL_TRIO PF00650.15 KND90782.1 - 3.8e-44 149.9 0.0 6.6e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND90782.1 - 2e-15 56.6 0.0 6e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KND90782.1 - 5.4e-10 39.3 0.0 9.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 KND90783.1 - 1.5e-07 31.8 0.0 0.011 16.2 0.1 2.5 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.3 KND90783.1 - 0.00011 22.3 0.0 0.00031 20.9 0.0 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RICTOR_N PF14664.1 KND90784.1 - 7.7e-137 455.8 1.5 1.4e-135 451.6 0.6 2.7 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KND90784.1 - 1.3e-87 292.5 0.6 9.8e-87 289.6 0.1 2.5 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KND90784.1 - 1.7e-41 140.7 0.1 1.1e-39 134.8 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KND90784.1 - 1e-28 99.0 0.2 5.9e-27 93.4 0.1 3.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KND90784.1 - 1e-13 50.8 6.4 1e-13 50.8 4.4 2.2 2 0 0 2 2 2 1 Hr1 repeat Uds1 PF15456.1 KND90784.1 - 0.014 15.3 8.0 0.047 13.6 5.6 1.9 1 0 0 1 1 1 0 Up-regulated During Septation IncA PF04156.9 KND90784.1 - 0.017 14.7 2.9 0.017 14.7 1.0 1.7 2 0 0 2 2 2 0 IncA protein Cas_Csx9 PF09658.5 KND90784.1 - 0.039 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) DEAD PF00270.24 KND90785.1 - 1.3e-44 151.6 0.0 2.1e-43 147.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND90785.1 - 3.6e-28 97.2 0.0 7.4e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_redox_2 PF07992.9 KND90785.1 - 1.4e-23 83.8 0.0 3.5e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND90785.1 - 1.3e-13 51.0 0.2 1.1e-11 44.9 0.0 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND90785.1 - 0.00016 21.8 1.4 2.7 8.0 0.0 3.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ResIII PF04851.10 KND90785.1 - 0.00019 21.3 0.0 0.00073 19.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KND90785.1 - 0.0069 14.8 0.0 0.15 10.3 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KND90785.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain AAR2 PF05282.6 KND90787.1 - 1.4e-39 136.1 0.0 9.1e-39 133.3 0.0 1.9 1 1 0 1 1 1 1 AAR2 protein DUF390 PF04094.9 KND90788.1 - 0.029 12.4 4.0 0.044 11.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF1682 PF07946.9 KND90788.1 - 1 8.1 5.1 1.3 7.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_L32e PF01655.13 KND90789.1 - 8.7e-50 167.3 1.3 8.7e-50 167.3 0.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L32 DUF716 PF04819.7 KND90790.1 - 0.034 13.5 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF716) Ribosomal_S9 PF00380.14 KND90791.1 - 2.6e-39 134.1 0.1 3e-39 134.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KND90791.1 - 0.07 10.5 0.0 0.079 10.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein OTU PF02338.14 KND90792.1 - 6.1e-10 39.7 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-A20 PF01754.11 KND90792.1 - 0.002 17.6 0.5 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 A20-like zinc finger Bromodomain PF00439.20 KND90793.1 - 6.1e-39 131.8 0.6 2e-20 72.4 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KND90793.1 - 1.1e-16 60.6 0.2 2.5e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 BAH domain Daxx PF03344.10 KND90793.1 - 1.1 7.7 24.7 0.05 12.0 8.5 2.2 2 0 0 2 2 2 0 Daxx Family RTA1 PF04479.8 KND90794.1 - 6.3e-15 55.2 1.9 1.3e-14 54.2 1.3 1.5 1 1 0 1 1 1 1 RTA1 like protein LHC PF00556.15 KND90794.1 - 0.61 9.9 4.6 1.2 9.0 2.3 2.2 1 1 0 1 1 1 0 Antenna complex alpha/beta subunit Inp1 PF12634.2 KND90795.1 - 4.2e-35 120.5 0.0 9.8e-35 119.3 0.0 1.6 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 KND90797.1 - 1.1e-05 25.0 14.6 0.00076 18.9 10.1 2.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PAT1 PF09770.4 KND90798.1 - 7.9 4.5 15.2 9.3 4.3 10.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 KND90799.1 - 1.2e-21 76.7 0.6 1.9e-21 76.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90799.1 - 0.00034 20.4 6.3 0.00067 19.5 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 KND90800.1 - 3.3e-39 134.6 0.0 4.5e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KND90800.1 - 0.0054 15.5 0.5 0.011 14.5 0.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family Rtf2 PF04641.7 KND90801.1 - 4.4e-50 170.2 0.3 6.5e-50 169.7 0.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KND90801.1 - 0.00014 21.5 0.2 0.00035 20.2 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KND90801.1 - 0.00066 19.4 0.2 0.0016 18.2 0.2 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND90801.1 - 0.0016 18.0 0.1 0.0026 17.3 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND90801.1 - 0.0018 17.9 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND90801.1 - 0.01 15.8 0.4 0.03 14.3 0.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KND90801.1 - 0.011 15.2 0.2 0.038 13.5 0.1 1.8 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 KND90801.1 - 0.02 14.4 0.5 0.05 13.1 0.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 WLM PF08325.5 KND90801.1 - 0.024 14.5 5.2 0.035 13.9 3.6 1.2 1 0 0 1 1 1 0 WLM domain zf-C2H2 PF00096.21 KND90802.1 - 0.015 15.6 0.9 0.015 15.6 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ring_hydroxyl_B PF00866.13 KND90802.1 - 0.031 13.9 0.3 0.073 12.7 0.1 1.6 1 1 0 1 1 1 0 Ring hydroxylating beta subunit zf-C2H2_4 PF13894.1 KND90802.1 - 0.051 13.9 8.4 0.056 13.8 0.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KND90802.1 - 0.07 13.0 2.7 0.11 12.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_EFTU PF00009.22 KND90803.1 - 6.1e-22 77.9 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KND90803.1 - 3.9e-15 55.8 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KND90803.1 - 3.1e-10 40.0 0.7 5.8e-09 35.9 0.3 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 KND90803.1 - 0.0025 18.3 0.1 0.03 14.8 0.1 2.7 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KND90803.1 - 0.006 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KND90803.1 - 0.015 14.7 0.3 1.7 8.1 0.1 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KND90803.1 - 0.046 12.8 0.2 0.085 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KND90803.1 - 0.1 12.4 1.3 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Dynamin family GTP_EFTU_D4 PF14578.1 KND90803.1 - 0.15 11.6 2.3 0.28 10.8 0.2 2.5 2 1 0 2 2 2 0 Elongation factor Tu domain 4 LSM PF01423.17 KND90804.1 - 1.4e-17 63.0 0.3 1.8e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain AKAP2_C PF15304.1 KND90805.1 - 3 7.3 13.0 5.5 6.5 9.0 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus CAP PF00188.21 KND90806.1 - 2.8e-15 56.8 4.0 4.2e-15 56.3 2.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Aldo_ket_red PF00248.16 KND90807.1 - 5.9e-52 176.2 0.0 8.3e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.18 KND90808.1 - 1.6e-22 80.4 0.2 4.1e-22 79.1 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND90808.1 - 1.1e-05 24.8 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KND90808.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KND90808.1 - 0.0013 17.4 0.0 0.011 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.9 KND90808.1 - 0.0038 16.3 0.0 0.13 11.3 0.0 2.6 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.14 KND90809.1 - 5.7e-98 327.9 0.0 6.7e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KND90809.1 - 0.044 12.3 0.0 0.7 8.4 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Beta-lactamase PF00144.19 KND90810.1 - 8.7e-21 74.2 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase UFD1 PF03152.9 KND90811.1 - 5.7e-25 87.4 0.0 3.9e-20 71.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 FtsJ PF01728.14 KND90813.1 - 8.5e-12 45.4 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.20 KND90814.1 - 1.8e-08 33.8 0.0 2.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KND90814.1 - 2.6e-05 23.6 0.0 9.4e-05 21.8 0.0 1.8 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 KND90814.1 - 7.1e-05 21.9 0.1 0.00013 21.0 0.0 1.5 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND90814.1 - 0.00015 21.5 0.3 0.0086 15.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KND90814.1 - 0.0018 17.4 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KND90814.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KND90814.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase eRF1_1 PF03463.10 KND90815.1 - 4e-36 123.5 0.0 7.6e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KND90815.1 - 1.4e-20 74.0 0.0 2.8e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KND90815.1 - 2.7e-16 59.8 0.0 4.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Filo_VP35 PF02097.10 KND90815.1 - 0.088 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Filoviridae VP35 Aldo_ket_red PF00248.16 KND90816.1 - 5.7e-39 133.6 0.0 7.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.15 KND90817.1 - 1.7e-21 75.8 0.0 2.1e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 KND90817.1 - 1.2e-06 28.0 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KND90817.1 - 9e-06 25.8 0.0 0.00013 22.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND90817.1 - 0.002 18.1 0.0 0.015 15.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KND90817.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like NdhO PF11910.3 KND90817.1 - 0.14 11.8 0.0 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O WD40 PF00400.27 KND90818.1 - 3.8e-31 105.8 8.0 3e-10 39.5 0.0 8.5 10 0 0 10 10 10 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KND90818.1 - 0.095 12.4 0.9 67 3.3 0.0 4.2 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Zn-ribbon_8 PF09723.5 KND90818.1 - 0.82 9.6 2.8 1.7 8.6 1.9 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AA_permease_2 PF13520.1 KND90819.1 - 1.6e-58 198.2 50.2 1.9e-58 197.9 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND90819.1 - 2.2e-32 112.0 47.7 3e-32 111.5 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.27 KND90820.1 - 9.7e-32 107.6 5.2 7.8e-11 41.4 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KND90820.1 - 1.9e-16 59.7 0.2 5.8e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex HpcH_HpaI PF03328.9 KND90821.1 - 4e-28 97.7 0.0 4.9e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RCC1 PF00415.13 KND90823.1 - 3.2e-61 203.3 1.3 5.2e-12 45.7 0.1 8.1 6 2 1 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KND90823.1 - 2.2e-34 116.3 28.5 5e-10 38.7 0.7 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat YadA_stalk PF05662.9 KND90823.1 - 2.2 8.2 5.8 24 4.8 1.2 3.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin MFS_1 PF07690.11 KND90825.1 - 1.5e-36 125.9 28.5 2.8e-36 124.9 19.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KND90825.1 - 0.41 10.7 4.2 1.1 9.3 0.0 3.3 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding DAO PF01266.19 KND90826.1 - 2.5e-19 69.4 0.9 4.7e-19 68.4 0.6 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND90826.1 - 0.018 15.0 0.2 0.051 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND90826.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fcf2 PF08698.6 KND90826.1 - 0.12 12.3 0.0 2.8 7.9 0.0 2.6 3 0 0 3 3 3 0 Fcf2 pre-rRNA processing NmrA PF05368.8 KND90827.1 - 7.9e-33 113.6 0.0 2.3e-32 112.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND90827.1 - 5.7e-12 46.0 0.1 8e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KND90827.1 - 0.00055 19.9 0.7 0.0011 18.8 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KND90827.1 - 0.0012 17.6 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KND90827.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KND90827.1 - 0.0058 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KND90827.1 - 0.0092 15.9 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 KND90827.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_23 PF13489.1 KND90828.1 - 6.9e-16 58.3 0.0 1.4e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND90828.1 - 4.4e-07 29.6 0.0 3e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND90828.1 - 7.3e-07 29.7 0.0 2.9e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND90828.1 - 3.9e-05 24.0 0.0 7.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND90828.1 - 0.00081 19.8 0.0 0.0032 17.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND90828.1 - 0.012 15.9 0.0 0.059 13.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KND90828.1 - 0.023 13.7 0.0 0.093 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 KND90828.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KND90828.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KND90828.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KND90828.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Yip1 PF04893.12 KND90830.1 - 4.7e-07 29.4 10.7 0.00013 21.4 4.7 2.6 2 1 0 2 2 2 2 Yip1 domain Sugar_tr PF00083.19 KND90831.1 - 4e-91 305.8 17.6 2.1e-90 303.4 12.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND90831.1 - 8.9e-21 73.9 24.2 1.5e-20 73.2 16.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 KND90831.1 - 0.00038 18.7 5.2 0.00081 17.6 3.6 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF441 PF04284.8 KND90831.1 - 0.00069 19.5 2.6 0.00084 19.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF441) PAP_assoc PF03828.14 KND90832.1 - 8.5e-14 51.2 0.1 1.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KND90832.1 - 7.6e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA PF00004.24 KND90833.1 - 2.3e-08 34.2 0.2 8.2e-08 32.5 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND90833.1 - 3.5e-05 24.6 0.0 0.00016 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 KND90833.1 - 0.00014 20.7 0.1 0.0044 15.7 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KND90833.1 - 0.0005 20.2 0.1 0.0018 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND90833.1 - 0.017 15.0 0.1 0.091 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 KND90833.1 - 0.02 14.5 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 KND90833.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KND90833.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KND90833.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Methyltransf_3 PF01596.12 KND90835.1 - 5.6e-08 32.0 0.2 2.2e-07 30.1 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase Fungal_trans_2 PF11951.3 KND90836.1 - 2e-25 89.2 2.3 6.9e-19 67.6 0.9 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90836.1 - 2.3e-06 27.4 2.4 5.1e-06 26.2 1.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_psq PF05225.11 KND90837.1 - 2.7e-12 46.0 0.2 3.6e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 KND90837.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 KND90837.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF3445 PF11927.3 KND90838.1 - 1.4e-64 217.8 0.0 7.6e-64 215.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) EutQ PF06249.7 KND90839.1 - 2.9e-11 43.1 0.0 3.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KND90839.1 - 1.8e-10 40.0 0.1 4.1e-10 38.9 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KND90839.1 - 0.00019 20.8 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KND90839.1 - 0.0055 16.3 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin KduI PF04962.7 KND90839.1 - 0.023 13.7 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Lactamase_B_3 PF13483.1 KND90839.1 - 0.081 12.6 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PAN_4 PF14295.1 KND90840.1 - 0.0022 17.6 41.9 0.022 14.4 0.8 5.6 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.7 KND90840.1 - 0.093 12.3 21.6 1.5 8.5 0.4 4.8 5 0 0 5 5 5 0 PAN-like domain Sugar_tr PF00083.19 KND90841.1 - 9.6e-77 258.4 19.3 1.2e-76 258.1 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND90841.1 - 3.9e-24 85.0 23.8 3.9e-24 85.0 16.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND90841.1 - 4.1e-07 28.5 0.8 6.7e-07 27.8 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.1 KND90842.1 - 6.5e-43 146.8 50.5 8.3e-43 146.4 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND90842.1 - 2e-19 69.3 45.3 2.7e-19 68.8 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease GspL_C PF12693.2 KND90842.1 - 0.21 11.3 0.3 0.47 10.2 0.2 1.6 1 0 0 1 1 1 0 GspL periplasmic domain DUF3948 PF13134.1 KND90842.1 - 2.8 7.4 5.7 1.8 8.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) DUF3445 PF11927.3 KND90844.1 - 9e-73 244.7 0.0 1.3e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF498 PF04430.9 KND90845.1 - 1.6e-25 88.7 0.0 2.1e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Med30 PF11315.3 KND90847.1 - 0.056 13.5 0.1 0.081 13.0 0.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 30 TPR_18 PF13512.1 KND90847.1 - 0.066 13.2 0.2 1.8 8.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FAR1 PF03101.10 KND90848.1 - 5.7e-05 23.5 0.0 8.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KND90848.1 - 0.0048 17.0 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT XhlA PF10779.4 KND90848.1 - 0.005 16.7 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Haemolysin XhlA Snapin_Pallidin PF14712.1 KND90848.1 - 0.0099 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Sugarporin_N PF11471.3 KND90848.1 - 0.021 14.4 1.3 0.031 13.9 0.0 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Hemagglutinin PF00509.13 KND90848.1 - 0.034 12.2 0.0 0.048 11.8 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF2360 PF10152.4 KND90848.1 - 0.045 14.0 0.2 0.098 12.9 0.0 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4631 PF15450.1 KND90848.1 - 0.073 11.3 0.0 0.09 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) YPEB PF14620.1 KND90848.1 - 0.078 11.9 0.0 0.15 11.0 0.0 1.4 2 0 0 2 2 2 0 YpeB sporulation DUF1664 PF07889.7 KND90848.1 - 0.088 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 KND90848.1 - 0.1 11.9 2.2 0.17 11.2 0.2 2.3 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin GOLGA2L5 PF15070.1 KND90848.1 - 0.11 11.0 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 MtrG PF04210.8 KND90848.1 - 0.12 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Dynamitin PF04912.9 KND90848.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Dynamitin Zn_clus PF00172.13 KND90849.1 - 4.7e-08 32.8 16.2 7.8e-08 32.0 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 KND90850.1 - 2.5e-60 204.7 0.0 1e-58 199.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KND90850.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Rad9 PF04139.8 KND90851.1 - 2.9e-64 216.6 0.4 3.5e-64 216.3 0.3 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.13 KND90852.1 - 9.9e-27 92.9 13.9 1.3e-12 47.7 0.0 6.4 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KND90852.1 - 3.2e-23 80.7 14.1 2.9e-08 33.0 0.4 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat NAD_binding_2 PF03446.10 KND90853.1 - 1.1e-05 25.2 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KND90853.1 - 1.2e-05 24.5 0.0 1.2e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KND90853.1 - 0.0002 21.7 0.0 0.00022 21.6 0.0 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KND90853.1 - 0.0031 16.9 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KND90853.1 - 0.0035 17.0 0.0 0.0041 16.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KND90853.1 - 0.0067 16.4 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain PDH PF02153.12 KND90854.1 - 2.7e-13 49.4 0.0 3.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase Asp PF00026.18 KND90855.1 - 1.9e-57 194.9 1.1 2.5e-57 194.5 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND90855.1 - 5.9e-10 39.3 0.1 4.6e-08 33.1 0.0 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KND90855.1 - 0.00015 21.3 0.1 0.011 15.2 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KND90855.1 - 0.0047 17.3 1.8 0.11 13.0 0.1 3.1 3 1 0 3 3 3 1 Aspartyl protease NAD_binding_10 PF13460.1 KND90856.1 - 9.6e-13 48.5 0.0 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KND90856.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Aldo_ket_red PF00248.16 KND90857.1 - 3.3e-37 127.8 0.0 1e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family SQS_PSY PF00494.14 KND90858.1 - 1.4e-54 185.1 0.0 1.8e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3782 PF12644.2 KND90858.1 - 0.095 12.5 0.1 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) LEA_6 PF10714.4 KND90858.1 - 0.12 12.1 0.4 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 SNF2_N PF00176.18 KND90859.1 - 2.7e-70 236.5 0.0 3.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KND90859.1 - 2.9e-24 85.0 0.0 5.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KND90859.1 - 4.1e-13 48.9 0.0 9e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KND90859.1 - 2.9e-07 30.4 6.9 5.8e-07 29.4 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND90859.1 - 9.2e-05 22.0 5.6 0.00017 21.1 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KND90859.1 - 0.00013 21.8 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KND90859.1 - 0.00016 21.2 6.6 0.00032 20.2 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND90859.1 - 0.00065 19.4 6.7 0.0013 18.5 4.6 1.6 1 0 0 1 1 1 1 Ring finger domain AAA_22 PF13401.1 KND90859.1 - 0.008 16.3 0.0 0.072 13.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain zf-RING_5 PF14634.1 KND90859.1 - 0.011 15.4 7.2 0.032 13.9 5.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain UBA_4 PF14555.1 KND90859.1 - 0.029 13.9 0.0 0.098 12.2 0.0 1.9 1 0 0 1 1 1 0 UBA-like domain DEAD_2 PF06733.10 KND90859.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 zf-RING_4 PF14570.1 KND90859.1 - 2 8.0 6.5 5 6.7 4.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Tom22 PF04281.8 KND90860.1 - 3e-43 146.6 0.0 3.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 ELFV_dehydrog PF00208.16 KND90861.1 - 1.3e-55 188.6 0.0 2.2e-55 187.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KND90861.1 - 2.4e-19 68.3 0.0 1.5e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase SH3_1 PF00018.23 KND90861.1 - 5e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain ELFV_dehydrog_N PF02812.13 KND90861.1 - 0.0028 17.2 0.0 0.0075 15.8 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SH3_9 PF14604.1 KND90861.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Nha1_C PF08619.5 KND90863.1 - 1.3e-72 245.4 42.3 3e-70 237.7 29.4 2.0 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KND90863.1 - 1.5e-65 221.2 19.4 1.8e-65 220.9 13.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KND90863.1 - 0.56 10.1 3.1 0.49 10.3 0.2 2.3 2 0 0 2 2 2 0 YrhC-like protein NYD-SP28 PF14772.1 KND90864.1 - 0.24 11.4 3.1 0.11 12.6 0.5 1.7 2 0 0 2 2 2 0 Sperm tail SAM_2 PF07647.12 KND90865.1 - 1.1e-15 57.1 0.0 2.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KND90865.1 - 2.7e-14 53.4 0.0 5.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 KND90865.1 - 4e-14 52.5 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.16 KND90866.1 - 4.1e-59 200.3 0.0 5.9e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KND90866.1 - 0.051 12.3 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 KND90866.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.23 KND90867.1 - 3.5e-52 177.2 0.0 4.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND90867.1 - 1.2e-05 26.1 0.0 3.7e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 KND90868.1 - 3.3e-46 153.5 20.0 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KND90868.1 - 0.00026 20.7 0.0 0.089 12.4 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 KND90868.1 - 0.12 11.5 0.7 0.18 11.0 0.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF2870 PF11069.3 KND90869.1 - 0.0085 16.1 0.3 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PIG-L PF02585.12 KND90870.1 - 6e-27 94.6 0.0 9.5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RR_TM4-6 PF06459.7 KND90871.1 - 0.48 10.2 6.4 0.8 9.5 4.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypsin_2 PF13365.1 KND90872.1 - 1.6e-14 53.9 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KND90872.1 - 1.1e-05 25.0 0.1 3.6e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.14 KND90872.1 - 0.0012 17.8 0.0 0.0051 15.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C4 Peptidase_S32 PF05579.8 KND90872.1 - 0.013 14.4 0.1 0.032 13.2 0.0 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 KND90872.1 - 0.019 13.4 0.0 0.045 12.1 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 Metallophos PF00149.23 KND90873.1 - 6.9e-18 64.7 0.0 3.3e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KND90873.1 - 1.7e-10 40.8 0.0 4.1e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KND90873.1 - 1.9e-06 26.7 0.0 9.3e-06 24.4 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 KND90873.1 - 4e-05 23.4 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 KND90873.1 - 0.035 14.2 0.3 0.073 13.2 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Ribosomal_S6 PF01250.12 KND90874.1 - 6.9e-08 32.2 0.0 8.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3716 PF12511.3 KND90875.1 - 1.8e-10 40.2 7.1 3.3e-10 39.3 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chs3p PF12271.3 KND90876.1 - 1.7e-137 457.2 12.5 1.9e-137 457.0 8.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KND90876.1 - 0.0016 18.2 1.0 0.0016 18.2 0.7 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3382) CTC1_2 PF15491.1 KND90876.1 - 0.16 10.9 0.3 0.27 10.2 0.0 1.4 2 0 0 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 Cullin_binding PF03556.10 KND90877.1 - 2.2e-31 108.4 2.8 4.6e-31 107.3 2.0 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KND90877.1 - 1.3e-08 34.1 0.0 2.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain PTCB-BRCT PF12738.2 KND90878.1 - 6.4e-40 134.8 0.1 2.7e-16 59.1 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 KND90878.1 - 1.1e-35 121.5 0.0 2.7e-11 43.4 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Cyclin PF08613.6 KND90879.1 - 1.8e-12 47.8 0.0 3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KND90879.1 - 1.4e-05 24.6 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain 4HBT_3 PF13622.1 KND90881.1 - 4.5e-43 147.8 0.2 1e-42 146.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily COX5B PF01215.14 KND90883.1 - 9.4e-37 125.7 0.0 1.4e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 KND90883.1 - 0.0057 16.1 0.2 1.7 8.2 0.0 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Glyco_transf_15 PF01793.11 KND90884.1 - 3.3e-128 427.3 3.1 4.3e-128 426.9 2.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L18e PF00828.14 KND90885.1 - 1.2e-20 74.1 0.9 2.1e-20 73.3 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Patatin PF01734.17 KND90885.1 - 0.12 12.2 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Patatin-like phospholipase PX PF00787.19 KND90886.1 - 2.7e-19 69.0 0.1 4.9e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 PX domain ILVD_EDD PF00920.16 KND90887.1 - 4.6e-192 639.0 1.5 5.5e-192 638.8 1.0 1.0 1 0 0 1 1 1 1 Dehydratase family DUF4449 PF14613.1 KND90888.1 - 2.2e-05 24.4 0.0 4e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 KND90888.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Utp21 PF04192.7 KND90889.1 - 0.0054 15.8 0.2 0.032 13.3 0.0 2.3 2 1 1 3 3 3 1 Utp21 specific WD40 associated putative domain DUF445 PF04286.7 KND90889.1 - 0.02 14.4 0.7 0.06 12.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Abhydrolase_6 PF12697.2 KND90890.1 - 1.1e-24 87.5 2.2 2.7e-24 86.3 1.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND90890.1 - 4.9e-17 62.0 0.1 5.8e-16 58.5 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KND90890.1 - 1.1e-09 37.9 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KND90890.1 - 6.1e-09 35.7 0.0 6.5e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KND90890.1 - 1.3e-07 32.1 0.0 2.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KND90890.1 - 8.9e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 KND90890.1 - 9.4e-05 22.5 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF2305 PF10230.4 KND90890.1 - 0.00059 19.3 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 KND90890.1 - 0.00067 19.3 0.0 0.0016 18.0 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Y_phosphatase PF00102.22 KND90890.1 - 0.0012 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.20 KND90890.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.13 KND90890.1 - 0.014 14.7 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.10 KND90890.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.3 KND90890.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) FSH1 PF03959.8 KND90890.1 - 0.052 12.9 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) VirJ PF06057.6 KND90890.1 - 0.056 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF900 PF05990.7 KND90890.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Alk_phosphatase PF00245.15 KND90891.1 - 1.2e-106 356.9 0.0 1.5e-106 356.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase MFS_1 PF07690.11 KND90891.1 - 9.5e-29 100.2 42.9 2.8e-27 95.3 14.1 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily Metalloenzyme PF01676.13 KND90891.1 - 0.0024 17.3 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 KND90891.1 - 2.2 7.9 5.7 0.48 10.1 0.4 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA CBS PF00571.23 KND90892.1 - 5.6e-16 58.0 5.6 6.5e-07 29.0 0.1 5.2 5 0 0 5 5 5 4 CBS domain Glyco_hydro_17 PF00332.13 KND90893.1 - 8.7e-08 31.5 0.7 1.4e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 KND90893.1 - 0.076 11.7 0.1 0.41 9.3 0.1 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 53 PAS_9 PF13426.1 KND90894.1 - 2e-31 108.4 0.0 3e-18 66.1 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KND90894.1 - 1.9e-18 66.3 0.0 5e-11 42.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 KND90894.1 - 1.5e-16 60.1 3.2 1.4e-06 28.0 0.0 4.8 4 1 0 4 4 4 3 PAS fold GATA PF00320.22 KND90894.1 - 6.8e-15 54.1 9.1 1.4e-14 53.1 6.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 KND90894.1 - 2.5e-11 43.5 3.7 5e-05 23.2 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KND90894.1 - 2e-07 31.0 0.0 0.065 13.2 0.0 3.5 3 0 0 3 3 3 2 PAS fold HEAT PF02985.17 KND90895.1 - 7.6e-19 66.0 11.3 0.029 14.4 0.0 10.2 11 0 0 11 11 9 5 HEAT repeat HEAT_2 PF13646.1 KND90895.1 - 4.4e-18 65.3 16.9 5e-09 36.3 0.1 8.2 5 3 5 10 10 10 7 HEAT repeats HEAT_EZ PF13513.1 KND90895.1 - 1.1e-15 57.6 17.6 1.4e-05 25.4 0.1 10.0 7 2 3 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KND90895.1 - 1.1e-10 41.8 1.3 0.016 15.5 0.0 7.6 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KND90895.1 - 4.9e-08 32.6 2.0 0.0015 17.9 0.1 5.3 5 1 1 6 6 6 1 CLASP N terminal MMS19_C PF12460.3 KND90895.1 - 7.4e-08 31.5 8.2 6.9e-07 28.3 0.2 4.0 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 KND90895.1 - 5.6e-06 26.1 0.0 0.013 15.1 0.1 4.7 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 KND90895.1 - 1.8e-05 24.6 4.3 0.038 13.8 0.5 4.5 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 KND90895.1 - 0.00022 20.7 0.5 3.1 7.2 0.0 5.3 6 1 0 6 6 6 1 Domain of unknown function (DUF4042) CAS_CSE1 PF03378.10 KND90895.1 - 0.00086 17.7 3.3 1.5 7.0 0.1 4.6 4 2 1 5 5 5 2 CAS/CSE protein, C-terminus V-ATPase_H_N PF03224.9 KND90895.1 - 0.0063 15.6 6.8 0.2 10.7 0.1 3.6 2 1 1 3 3 3 1 V-ATPase subunit H DUF3554 PF12074.3 KND90895.1 - 0.0084 15.5 1.4 3.7 6.8 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF3554) FAA_hydrolase_N PF09298.6 KND90895.1 - 0.036 14.0 0.2 0.6 10.1 0.1 3.0 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal IBN_N PF03810.14 KND90895.1 - 0.04 13.8 0.0 0.3 11.0 0.0 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain DRIM PF07539.7 KND90895.1 - 0.067 12.6 0.5 0.27 10.6 0.4 2.0 1 0 0 1 1 1 0 Down-regulated in metastasis DUF1664 PF07889.7 KND90895.1 - 0.18 11.6 1.7 21 4.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Coatomer_WDAD PF04053.9 KND90896.1 - 2.8e-150 501.0 0.0 4.9e-150 500.1 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KND90896.1 - 2.1e-84 283.4 0.0 3e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KND90896.1 - 5.2e-50 165.6 11.9 2.4e-09 36.7 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KND90896.1 - 0.034 12.2 6.2 0.32 9.0 0.0 3.5 2 1 2 4 4 4 0 Nucleoporin Nup120/160 UDP-g_GGTase PF06427.6 KND90898.1 - 1.3e-59 201.0 0.0 5.3e-59 199.0 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KND90898.1 - 0.0001 21.7 0.4 0.00024 20.5 0.3 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Sel1 PF08238.7 KND90899.1 - 1.3e-13 51.0 27.3 4.7e-05 23.8 0.0 7.0 7 0 0 7 7 7 5 Sel1 repeat TPR_11 PF13414.1 KND90899.1 - 0.0091 15.6 1.9 0.12 11.9 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KND90899.1 - 0.04 13.5 0.1 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND90899.1 - 6.8 6.7 6.3 0.59 10.0 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 KND90900.1 - 1.4e-26 93.3 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KND90900.1 - 1e-21 77.2 0.0 1.6e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Phos_pyr_kin PF08543.7 KND90901.1 - 1.5e-72 243.7 0.6 1.9e-38 132.0 0.0 2.3 1 1 1 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KND90901.1 - 3e-47 161.0 0.0 4.5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KND90901.1 - 3.5e-07 29.6 0.0 7.9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Rsa3 PF14615.1 KND90903.1 - 9.6e-18 63.2 0.1 1.2e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 THUMP PF02926.12 KND90903.1 - 0.061 13.2 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 THUMP domain Ytp1 PF10355.4 KND90904.1 - 4.9e-106 353.8 8.2 7.7e-106 353.2 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KND90904.1 - 1.1e-31 108.4 6.4 1.1e-31 108.4 4.5 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Lactamase_B PF00753.22 KND90905.1 - 6.1e-24 84.7 2.2 9.5e-24 84.1 1.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND90905.1 - 4e-05 23.2 0.2 5.6e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KND90905.1 - 0.0039 16.9 0.1 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mito_carr PF00153.22 KND90906.1 - 4e-43 145.0 1.2 2.4e-16 59.1 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_10 PF13460.1 KND90907.1 - 8.4e-16 58.4 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND90907.1 - 4.9e-14 52.3 0.0 8.7e-14 51.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND90907.1 - 1e-12 47.8 0.0 1.5e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.14 KND90907.1 - 1.4e-09 37.1 0.1 2.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KND90907.1 - 5.4e-08 32.0 0.0 1.1e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KND90907.1 - 0.00033 19.6 0.5 0.02 13.8 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KND90907.1 - 0.00079 19.1 0.1 0.58 9.7 0.0 3.1 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KND90907.1 - 0.001 19.0 0.1 0.0037 17.2 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 KND90907.1 - 0.028 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UCH PF00443.24 KND90908.1 - 1.3e-53 181.8 5.2 1.9e-53 181.2 3.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND90908.1 - 2.2e-30 106.1 3.9 3e-30 105.6 2.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SNF2_N PF00176.18 KND90909.1 - 7.7e-68 228.4 0.0 1e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KND90909.1 - 1.3e-59 201.2 2.4 1e-58 198.3 2.0 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KND90909.1 - 4.3e-13 48.9 0.0 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KND90909.1 - 3.8e-07 29.2 0.0 1.8e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KND90909.1 - 5.6e-07 29.5 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND90909.1 - 0.045 13.9 0.0 0.52 10.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain Gaa1 PF04114.9 KND90910.1 - 6.3e-96 322.0 15.3 7.3e-94 315.2 10.6 2.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 KND90911.1 - 3.7e-09 36.8 0.0 9.1e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain YhhN PF07947.9 KND90912.1 - 1.2e-35 122.6 19.7 1.5e-35 122.2 13.7 1.1 1 0 0 1 1 1 1 YhhN-like protein DUF3814 PF12769.2 KND90912.1 - 0.23 11.6 5.1 0.62 10.2 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) adh_short_C2 PF13561.1 KND90913.1 - 4.4e-31 108.4 0.1 5e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND90913.1 - 3.6e-28 98.5 0.4 4.7e-28 98.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND90913.1 - 4.3e-14 52.5 0.2 6e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KND90913.1 - 0.13 11.8 2.9 0.38 10.2 0.2 2.9 2 2 1 3 3 3 0 Zinc-binding dehydrogenase Noc2 PF03715.8 KND90917.1 - 2.8e-118 394.1 0.0 7.3e-118 392.7 0.0 1.7 2 0 0 2 2 2 1 Noc2p family CobN-Mg_chel PF02514.11 KND90917.1 - 0.03 11.7 3.5 0.052 10.9 2.4 1.4 1 0 0 1 1 1 0 CobN/Magnesium Chelatase adh_short PF00106.20 KND90917.1 - 0.042 13.7 2.6 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 short chain dehydrogenase Cep57_MT_bd PF06657.8 KND90918.1 - 1.2e-27 95.6 0.1 1.2e-27 95.6 0.1 4.4 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KND90918.1 - 2.2e-24 85.1 19.8 1.5e-13 50.4 5.6 6.1 4 1 2 6 6 6 3 Centrosome localisation domain of PPC89 CCDC155 PF14662.1 KND90918.1 - 0.00036 20.2 50.0 0.0016 18.1 9.6 4.7 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 HALZ PF02183.13 KND90918.1 - 0.0083 15.8 1.8 0.0083 15.8 1.2 9.1 5 1 3 9 9 9 3 Homeobox associated leucine zipper DUF904 PF06005.7 KND90918.1 - 0.08 13.2 68.8 0.31 11.3 4.4 7.9 5 2 3 8 8 7 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 KND90918.1 - 0.099 12.5 55.8 0.11 12.3 10.7 4.4 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KND90918.1 - 0.26 10.8 56.6 0.12 11.9 8.9 5.3 2 1 1 4 4 4 0 IncA protein bZIP_1 PF00170.16 KND90918.1 - 0.33 10.9 43.8 0.18 11.7 2.3 7.7 7 1 1 8 8 8 0 bZIP transcription factor DUF2353 PF09789.4 KND90918.1 - 5 6.2 55.8 0.0073 15.5 18.5 3.2 3 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) APG6 PF04111.7 KND90918.1 - 5.3 5.9 56.0 0.025 13.6 10.3 4.0 2 1 2 4 4 4 0 Autophagy protein Apg6 Sbi-IV PF11621.3 KND90918.1 - 6 7.0 15.7 4.4 7.5 0.3 4.3 4 0 0 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI Kinetocho_Slk19 PF12709.2 KND90918.1 - 9.5 6.3 31.9 0.66 10.0 0.1 6.5 3 1 2 7 7 7 0 Central kinetochore-associated HeLo PF14479.1 KND90919.1 - 4.6e-24 85.3 0.0 4.8e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation EVE PF01878.13 KND90920.1 - 4.9e-45 153.0 0.0 8e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 EVE domain Mitofilin PF09731.4 KND90920.1 - 2.1 6.8 11.1 2.8 6.4 7.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.8 KND90920.1 - 7.1 5.9 10.4 11 5.2 7.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3591 PF12157.3 KND90921.1 - 3.2e-168 559.8 0.2 5.3e-168 559.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KND90921.1 - 0.014 15.0 1.2 0.014 15.0 0.8 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 KND90921.1 - 0.025 14.4 0.9 0.025 14.4 0.6 2.0 2 0 0 2 2 2 0 Zinc knuckle 2OG-FeII_Oxy PF03171.15 KND90923.1 - 0.0047 17.1 0.0 0.01 16.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 KND90924.1 - 6e-52 175.8 0.0 1e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KND90924.1 - 0.00083 19.4 0.0 0.012 15.7 0.0 2.1 1 1 0 2 2 2 1 Fascin domain bZIP_Maf PF03131.12 KND90924.1 - 0.064 13.5 2.2 0.064 13.5 1.5 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40 PF00400.27 KND90925.1 - 1.5e-12 46.8 0.5 0.014 15.2 0.0 4.7 4 1 0 4 4 4 4 WD domain, G-beta repeat Mito_carr PF00153.22 KND90926.1 - 3.8e-65 215.6 2.8 3.2e-22 78.0 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Ribosomal_L24e PF01246.15 KND90927.1 - 9.7e-29 99.0 2.5 1.7e-28 98.2 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e SRP_SPB PF02978.14 KND90927.1 - 0.069 13.4 0.4 0.16 12.2 0.3 1.8 1 1 0 1 1 1 0 Signal peptide binding domain TPR_11 PF13414.1 KND90928.1 - 0.017 14.7 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 KND90928.1 - 0.032 14.1 0.4 0.15 12.0 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat FUSC PF04632.7 KND90928.1 - 8.6 4.6 6.9 11 4.2 4.7 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family GMC_oxred_C PF05199.8 KND90930.1 - 7.2e-39 133.3 0.1 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KND90930.1 - 5.3e-35 121.0 0.1 1.4e-34 119.6 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND90931.1 - 7.7e-39 133.2 0.1 1.2e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KND90931.1 - 5.8e-35 120.8 0.0 1.6e-34 119.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase DsbB PF02600.11 KND90932.1 - 0.16 11.7 11.2 0.41 10.4 7.8 1.6 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB ADH_N PF08240.7 KND90933.1 - 8.8e-09 35.0 2.9 1e-08 34.8 0.3 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND90933.1 - 0.00042 21.2 0.0 0.0021 18.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.1 KND90934.1 - 2.8e-09 36.6 9.9 2.8e-09 36.6 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 KND90934.1 - 2.2e-06 27.3 3.3 2.2e-06 27.3 2.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KND90934.1 - 3.7e-05 23.7 4.4 3.7e-05 23.7 3.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 KND90934.1 - 0.00013 21.8 13.8 0.0017 18.3 6.4 2.8 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.1 KND90934.1 - 0.0032 17.1 9.3 0.0032 17.1 6.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KND90934.1 - 0.01 15.4 6.4 0.01 15.4 4.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KND90934.1 - 0.011 15.7 3.0 0.041 13.8 2.1 2.0 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 KND90934.1 - 0.015 15.2 10.1 0.015 15.2 7.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KND90934.1 - 0.29 10.9 4.0 0.72 9.6 2.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger RINGv PF12906.2 KND90934.1 - 2.5 8.2 16.6 0.13 12.3 7.5 2.0 2 0 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.1 KND90934.1 - 4.9 6.8 15.7 0.13 11.8 6.1 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KND90934.1 - 6.7 6.4 19.3 0.097 12.3 6.7 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NAPRTase PF04095.11 KND90935.1 - 6.1e-55 186.1 0.1 2e-54 184.4 0.1 1.7 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WSC PF01822.14 KND90936.1 - 1.4e-18 66.6 6.8 3.8e-18 65.1 4.7 1.8 1 0 0 1 1 1 1 WSC domain ENTH PF01417.15 KND90936.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 ENTH domain Macoilin PF09726.4 KND90936.1 - 7.3 4.7 5.3 8.3 4.5 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CactinC_cactus PF09732.4 KND90937.1 - 3.4e-54 181.7 4.2 5.4e-54 181.1 2.9 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 KND90937.1 - 2.4e-53 180.2 0.9 3.2e-53 179.8 0.6 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin dNK PF01712.14 KND90937.1 - 0.059 13.2 0.5 0.8 9.6 0.2 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Fungal_trans PF04082.13 KND90938.1 - 1e-21 77.0 0.0 1.7e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90938.1 - 9.5e-09 35.0 9.9 1.7e-08 34.2 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND90940.1 - 1.1e-13 50.6 0.0 2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND90940.1 - 1.1e-06 28.3 9.6 1.1e-06 28.3 6.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KND90942.1 - 8.7e-11 41.0 0.0 5.8e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Thioredoxin_4 PF13462.1 KND90943.1 - 0.00025 21.1 0.0 0.00053 20.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KND90943.1 - 0.0024 17.4 3.1 0.11 12.0 0.2 2.5 1 1 1 2 2 2 2 DSBA-like thioredoxin domain ScdA_N PF04405.9 KND90943.1 - 0.12 11.7 1.5 0.98 8.8 0.0 2.5 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) Abhydrolase_3 PF07859.8 KND90944.1 - 1.8e-37 128.9 0.0 2.2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KND90944.1 - 2.5e-10 39.5 0.0 3.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KND90944.1 - 3.7e-07 30.0 0.0 4.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KND90944.1 - 9.4e-05 22.7 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF3089 PF11288.3 KND90944.1 - 0.0015 17.7 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Peptidase_S9 PF00326.16 KND90944.1 - 0.0089 15.2 0.0 0.031 13.4 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family NACHT PF05729.7 KND90946.1 - 1.4e-12 47.6 1.9 9.2e-05 22.1 0.0 4.4 4 1 0 4 4 4 2 NACHT domain AAA_16 PF13191.1 KND90946.1 - 0.00013 22.0 0.0 0.00065 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND90946.1 - 0.00019 21.5 0.0 0.0036 17.4 0.0 3.1 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KND90946.1 - 0.00052 20.1 0.0 0.0067 16.5 0.0 2.7 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 KND90946.1 - 0.0057 16.1 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 KND90946.1 - 0.0073 15.1 0.0 0.024 13.4 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KND90946.1 - 0.029 14.6 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 KND90946.1 - 0.046 13.5 0.1 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 UPF0128 PF03673.8 KND90946.1 - 0.049 12.9 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) AAA PF00004.24 KND90946.1 - 0.053 13.7 0.0 8 6.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KND90946.1 - 0.066 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KND90946.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KND90946.1 - 0.087 12.6 0.1 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PNP_UDP_1 PF01048.15 KND90947.1 - 3.8e-15 55.5 1.2 2.5e-14 52.8 0.8 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily MgtE PF01769.11 KND90948.1 - 0.016 15.4 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 Divalent cation transporter FecCD PF01032.13 KND90948.1 - 0.033 13.0 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 FecCD transport family UPF0197 PF05251.7 KND90948.1 - 0.097 12.9 0.2 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF4418 PF14387.1 KND90948.1 - 0.11 12.2 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) PNP_UDP_1 PF01048.15 KND90949.1 - 3.2e-08 32.8 0.0 3.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Slx4 PF09494.5 KND90951.1 - 9e-23 79.8 0.0 1.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Ribosomal_S21e PF01249.13 KND90952.1 - 1e-40 137.5 0.1 1.2e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.9 KND90953.1 - 3.4e-104 347.9 0.0 7.1e-104 346.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KND90953.1 - 1.7e-39 135.2 0.1 3.3e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 KND90953.1 - 0.015 15.5 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family XLF PF09302.6 KND90954.1 - 4.3e-19 68.9 0.0 1.2e-17 64.1 0.0 2.2 1 1 0 1 1 1 1 XLF (XRCC4-like factor) Lamp PF01299.12 KND90954.1 - 8.3 5.4 5.7 14 4.7 4.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Fork_head PF00250.13 KND90955.1 - 7.3e-15 54.7 0.1 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Fork head domain WD40 PF00400.27 KND90956.1 - 1.2e-06 28.1 18.7 0.34 10.8 0.0 8.1 10 1 0 10 10 10 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KND90956.1 - 2.1e-05 24.0 1.8 0.0001 21.8 0.1 2.6 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 KND90956.1 - 0.072 11.8 0.3 0.38 9.4 0.0 2.2 3 1 0 3 3 3 0 Nup133 N terminal like DUF3312 PF11768.3 KND90956.1 - 0.11 10.7 0.3 0.31 9.1 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) CDP-OH_P_transf PF01066.16 KND90957.1 - 1.5e-17 63.7 5.5 1.5e-17 63.7 3.8 2.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase PLDc_2 PF13091.1 KND90958.1 - 1.6e-17 63.3 0.0 8.1e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KND90958.1 - 0.00014 21.5 0.1 0.0076 16.0 0.0 2.6 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KND90958.1 - 0.012 14.5 0.0 0.044 12.7 0.0 1.8 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB PFL PF02901.10 KND90958.1 - 0.035 12.5 0.0 0.049 12.0 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase F-box PF00646.28 KND90959.1 - 0.00066 19.2 1.1 0.0014 18.2 0.7 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KND90959.1 - 0.51 10.1 4.1 0.11 12.1 0.5 1.8 2 0 0 2 2 2 0 F-box-like Peptidase_M28 PF04389.12 KND90960.1 - 1.9e-33 115.6 0.0 2.6e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Epimerase PF01370.16 KND90962.1 - 3.5e-18 65.9 0.1 8.6e-18 64.6 0.1 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND90962.1 - 3.9e-14 53.0 0.6 1.5e-13 51.1 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND90962.1 - 9.8e-12 44.1 0.0 1.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND90962.1 - 5.1e-07 28.8 0.0 7.3e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KND90962.1 - 3.4e-06 27.0 2.1 4.4e-06 26.7 0.5 1.9 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KND90962.1 - 3.1e-05 23.3 0.1 5.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KND90962.1 - 0.00096 18.8 2.1 0.0011 18.6 0.4 1.9 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 KND90962.1 - 0.0043 15.9 0.0 3.6 6.3 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KND90962.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UAA PF08449.6 KND90963.1 - 7.9e-12 44.6 16.6 1e-11 44.3 11.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KND90963.1 - 2.4e-10 40.2 5.9 2.4e-10 40.2 4.1 2.8 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KND90963.1 - 0.012 15.6 25.5 0.025 14.6 5.8 2.4 2 0 0 2 2 2 0 EamA-like transporter family IF4E PF01652.13 KND90964.1 - 4.5e-60 201.9 0.1 5.5e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Translin PF01997.11 KND90965.1 - 2.2e-50 171.0 0.0 2.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.18 KND90965.1 - 0.0081 16.3 1.1 0.039 14.1 0.8 2.1 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Mannosyl_trans PF05007.8 KND90966.1 - 3.1e-80 269.5 10.3 4e-80 269.1 7.2 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KND90966.1 - 3.7e-10 39.2 15.6 1.3e-09 37.3 10.8 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KND90966.1 - 2.2e-06 27.3 27.9 2.2e-06 27.3 19.3 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2029) SQS_PSY PF00494.14 KND90967.1 - 8.1e-40 136.7 0.0 2e-39 135.4 0.0 1.6 2 0 0 2 2 2 1 Squalene/phytoene synthase RmlD_sub_bind PF04321.12 KND90968.1 - 6.9e-11 41.5 0.0 1.8e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KND90968.1 - 4.8e-10 39.2 0.0 7.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KND90968.1 - 0.00022 20.2 0.0 0.00047 19.1 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein F-box-like PF12937.2 KND90969.1 - 0.00044 19.9 0.2 0.0019 17.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like Peptidase_S8 PF00082.17 KND90970.1 - 2.7e-47 161.2 16.5 4e-47 160.6 11.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND90970.1 - 0.0019 18.7 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M19 PF01244.16 KND90970.1 - 0.0066 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ELH PF02323.10 KND90970.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor PBP_sp32 PF07222.7 KND90971.1 - 1.9 7.6 4.6 0.46 9.6 0.3 2.0 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Tnp_P_element PF12017.3 KND90971.1 - 2 7.6 3.4 2.6 7.2 0.1 2.1 2 0 0 2 2 2 0 Transposase protein ATAD4 PF15321.1 KND90971.1 - 6.4 7.8 8.3 1.7 9.6 0.6 3.2 3 0 0 3 3 3 0 ATPase family AAA domain containing 4 Cyt-b5 PF00173.23 KND90972.1 - 1.6e-15 56.6 0.0 2.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ-X PF14308.1 KND90973.1 - 2.5e-71 239.1 1.5 2.5e-71 239.1 1.0 2.7 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KND90973.1 - 9.4e-26 89.3 1.0 2.5e-25 88.0 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain PIRT PF15099.1 KND90974.1 - 0.03 13.5 0.2 0.037 13.2 0.1 1.3 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Rad1 PF02144.11 KND90975.1 - 2.3e-81 272.5 0.0 2.6e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 APC_CDC26 PF10471.4 KND90977.1 - 4.9e-14 52.8 0.8 5.5e-14 52.6 0.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 PQ-loop PF04193.9 KND90979.1 - 1.9e-24 84.9 2.8 1.3e-14 53.4 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat ADH_N PF08240.7 KND90980.1 - 1.2e-28 99.0 4.5 1.2e-28 99.0 3.1 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND90980.1 - 1.8e-19 69.5 0.1 3.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND90980.1 - 0.0026 18.6 0.0 0.0057 17.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KND90980.1 - 0.056 13.0 0.4 0.086 12.4 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyco_trans_4_2 PF13477.1 KND90980.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like TrkA_N PF02254.13 KND90980.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AMP-binding PF00501.23 KND90981.1 - 1e-70 238.2 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND90981.1 - 2.2e-12 47.7 2.0 4.7e-12 46.6 0.1 2.6 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain FYVE_2 PF02318.11 KND90982.1 - 0.0071 16.2 1.5 0.0071 16.2 1.1 1.8 3 0 0 3 3 3 1 FYVE-type zinc finger IBR PF01485.16 KND90982.1 - 0.12 12.2 3.3 0.33 10.8 2.3 1.7 1 1 0 1 1 1 0 IBR domain DZR PF12773.2 KND90982.1 - 0.16 11.8 5.4 3.5 7.5 3.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon C6_DPF PF10170.4 KND90982.1 - 0.55 10.3 2.8 1.3 9.1 1.9 1.6 1 0 0 1 1 1 0 Cysteine-rich domain zf-C3HC4_2 PF13923.1 KND90982.1 - 2.6 8.1 9.9 0.19 11.7 3.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Thiolase_N PF00108.18 KND90983.1 - 2.8e-92 308.4 0.2 3.9e-92 307.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND90983.1 - 1.3e-44 150.5 0.8 3.8e-44 149.0 0.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KND90983.1 - 0.00015 21.3 2.6 0.00015 21.3 1.8 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KND90984.1 - 3.5e-35 121.9 0.0 4.2e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND90984.1 - 9.5e-29 100.4 0.0 1.5e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND90984.1 - 1.6e-11 44.1 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND90984.1 - 4.4e-05 23.0 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND90984.1 - 0.073 13.0 0.3 0.3 11.0 0.2 2.0 2 1 0 2 2 2 0 NADH(P)-binding DUF1776 PF08643.5 KND90984.1 - 0.16 11.0 0.0 1.5 7.8 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 KND90985.1 - 3.5e-25 88.8 0.7 5.1e-25 88.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND90985.1 - 6.5e-12 45.7 0.0 8.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND90985.1 - 5e-09 36.0 0.0 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND90985.1 - 9.2e-07 29.0 0.8 5.2e-06 26.5 0.1 2.4 2 1 0 3 3 3 1 NADH(P)-binding DUF1776 PF08643.5 KND90985.1 - 5.2e-06 25.8 0.0 1.1e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 KND90985.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.8 KND90985.1 - 0.1 11.8 0.1 0.21 10.7 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 KND90985.1 - 0.11 12.0 0.5 0.25 10.8 0.4 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 KND90986.1 - 1e-29 103.3 55.2 2.4e-25 88.9 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND90986.1 - 2.4e-05 23.1 45.6 0.0035 15.9 12.4 2.7 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KND90986.1 - 0.0098 15.6 0.7 0.0098 15.6 0.5 3.2 3 0 0 3 3 3 1 MFS_1 like family MFS_1 PF07690.11 KND90988.1 - 1.4e-16 60.2 50.1 1.4e-16 60.2 34.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PIP5K PF01504.13 KND90989.1 - 1.1e-51 175.3 0.0 3.2e-51 173.8 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KND90989.1 - 3.2e-22 78.8 0.0 5.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KND90989.1 - 1.4e-14 53.6 10.1 3.5e-14 52.4 7.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF2404 PF10296.4 KND90990.1 - 0.0038 17.3 0.0 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Glycos_transf_1 PF00534.15 KND90991.1 - 8.8e-16 57.7 0.0 2.1e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KND90991.1 - 9.2e-07 28.6 0.0 6e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KND90991.1 - 0.0003 20.9 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_11 PF13414.1 KND90993.1 - 9.7e-52 172.5 28.4 2.5e-16 59.0 0.5 6.4 4 2 2 6 6 6 6 TPR repeat Zip PF02535.17 KND90993.1 - 6.6e-49 166.6 1.5 6.6e-49 166.6 1.0 2.0 2 1 0 2 2 2 1 ZIP Zinc transporter TPR_1 PF00515.23 KND90993.1 - 1.4e-35 119.4 28.7 6.2e-07 28.7 0.6 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KND90993.1 - 6e-30 100.7 25.9 1.9e-05 24.2 0.2 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KND90993.1 - 5.2e-16 58.8 9.4 0.00017 22.1 0.0 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KND90993.1 - 1.5e-15 56.2 4.0 0.12 13.0 0.0 8.4 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND90993.1 - 2.9e-15 55.9 14.1 1.2e-10 41.1 1.2 5.6 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KND90993.1 - 2.4e-12 46.0 6.3 0.28 11.4 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KND90993.1 - 2.4e-11 42.5 18.4 0.0041 16.7 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND90993.1 - 1.4e-09 37.0 2.2 0.11 12.3 0.2 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND90993.1 - 7.4e-08 32.6 7.9 0.0058 16.9 0.1 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND90993.1 - 1.2e-07 31.4 0.2 0.011 15.5 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND90993.1 - 0.0012 19.1 10.0 4.7 7.8 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KND90993.1 - 0.0029 17.7 10.4 0.0096 16.0 1.4 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KND90993.1 - 0.059 13.3 0.0 0.36 10.8 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.13 KND90993.1 - 0.26 11.1 13.1 2.6 7.9 0.1 4.8 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KND90993.1 - 2 8.2 11.8 2.2 8.1 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 KND90994.1 - 1.4e-29 103.6 0.0 1.7e-28 100.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KND90994.1 - 4e-14 51.7 0.0 2.4e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KND90994.1 - 3.1e-10 39.9 0.0 1.4e-08 34.6 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KND90994.1 - 9.2e-08 31.3 0.1 4.1e-06 25.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KND90994.1 - 7.7e-07 29.4 0.2 0.014 15.7 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND90994.1 - 2.8e-06 26.5 0.0 0.003 16.6 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KND90994.1 - 1.4e-05 24.1 0.1 0.019 13.9 0.0 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND90994.1 - 0.00086 19.1 4.1 2.3 7.9 0.2 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND90994.1 - 0.0009 19.1 0.0 0.1 12.4 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND90994.1 - 0.0015 17.4 0.1 0.0097 14.8 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 KND90994.1 - 0.0028 17.7 0.0 0.36 10.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KND90994.1 - 0.0063 15.4 0.0 0.16 10.7 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 KND90994.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Mqo PF06039.10 KND90994.1 - 0.03 12.5 0.1 0.62 8.1 0.0 2.5 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.19 KND90994.1 - 0.063 12.3 0.0 0.19 10.7 0.0 1.8 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KND90994.1 - 0.076 11.8 0.1 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KND90994.1 - 0.16 10.4 0.1 5 5.4 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein Rhodanese PF00581.15 KND90996.1 - 2.2e-07 31.2 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain LSM PF01423.17 KND90997.1 - 2.8e-19 68.4 0.1 3.3e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3844 PF12955.2 KND90998.1 - 3.3e-28 97.7 0.4 5.3e-28 97.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Zn_clus PF00172.13 KND90999.1 - 0.25 11.2 4.5 0.62 10.0 3.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Bromodomain PF00439.20 KND91000.1 - 2.7e-31 107.3 0.2 6.7e-15 54.7 0.0 2.4 2 0 0 2 2 2 2 Bromodomain KAR9 PF08580.5 KND91000.1 - 0.0041 15.4 0.5 0.0041 15.4 0.3 1.7 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Nop14 PF04147.7 KND91000.1 - 0.067 11.1 5.9 0.091 10.6 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KND91000.1 - 0.22 9.5 5.0 0.32 8.9 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 KND91000.1 - 3.1 7.8 8.3 0.28 11.2 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) p450 PF00067.17 KND91002.1 - 2.6e-69 233.9 0.0 3.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 KND91003.1 - 7.3e-20 71.7 0.6 9.6e-20 71.3 0.4 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 KND91004.1 - 6.3e-41 140.2 53.7 9.6e-41 139.6 35.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 KND91005.1 - 2.9e-47 161.5 0.0 3.7e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 KND91006.1 - 1.3e-71 241.4 22.3 1.5e-71 241.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91006.1 - 3.4e-13 49.0 35.6 3.4e-13 49.0 24.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KND91006.1 - 2e-05 23.1 19.5 0.0064 14.9 5.0 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein Herpes_US9 PF06072.6 KND91006.1 - 0.039 13.7 0.5 1.3 8.9 0.0 3.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Sugar_tr PF00083.19 KND91007.1 - 3e-79 266.7 28.0 3.5e-79 266.5 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91007.1 - 2.8e-12 46.0 29.8 2.8e-12 46.0 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfate_transp PF00916.15 KND91008.1 - 6.4e-52 176.2 3.3 9.9e-52 175.6 2.3 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KND91008.1 - 8.1e-30 102.3 0.8 8.1e-30 102.3 0.6 2.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KND91008.1 - 1.9e-11 43.4 0.0 3.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain Cupin_1 PF00190.17 KND91009.1 - 6.5e-31 106.6 0.0 2e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KND91009.1 - 2.8e-26 90.8 1.0 2.4e-12 46.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KND91009.1 - 7.1e-10 38.1 0.1 0.00039 19.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KND91009.1 - 2.3e-07 30.5 0.1 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KND91009.1 - 0.00083 18.9 0.0 0.094 12.3 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 KND91009.1 - 0.026 14.4 0.9 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 KND91009.1 - 0.041 13.3 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase DUF1275 PF06912.6 KND91010.1 - 1.7e-33 115.6 13.3 2.2e-33 115.2 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 KND91010.1 - 0.11 11.1 17.5 0.097 11.3 2.7 2.9 2 1 1 3 3 3 0 Major Facilitator Superfamily MFS_1 PF07690.11 KND91011.1 - 8.4e-07 28.0 1.0 1e-06 27.7 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nuc_sug_transp PF04142.10 KND91011.1 - 0.042 12.9 0.4 0.056 12.5 0.3 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter UNC-50 PF05216.8 KND91011.1 - 0.087 12.0 0.1 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 UNC-50 family DcuA_DcuB PF03605.9 KND91011.1 - 0.089 11.6 0.1 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter NADH-u_ox-rdase PF10785.4 KND91011.1 - 0.13 12.5 0.7 0.19 12.0 0.5 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Fungal_trans PF04082.13 KND91012.1 - 7.1e-24 84.0 1.9 1.4e-23 83.0 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91012.1 - 4.7e-11 42.4 9.9 1.1e-10 41.1 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KND91013.1 - 1.9e-29 102.6 0.0 4.6e-29 101.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91013.1 - 3.7e-11 42.5 0.0 0.00024 20.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KND91013.1 - 0.036 13.7 0.2 0.12 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Thioredoxin PF00085.15 KND91014.1 - 1.6e-25 88.7 0.0 1.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KND91014.1 - 2.7e-07 30.7 0.1 3.2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND91014.1 - 5.5e-07 29.6 0.0 7.5e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KND91014.1 - 0.00088 18.8 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 KND91014.1 - 0.0009 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.1 KND91014.1 - 0.0043 17.0 0.1 0.007 16.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KND91014.1 - 0.0086 15.6 0.3 0.2 11.1 0.1 2.0 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.19 KND91014.1 - 0.041 13.8 0.0 0.092 12.7 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.16 KND91014.1 - 0.091 12.4 0.1 3.3 7.3 0.0 2.1 1 1 0 2 2 2 0 AhpC/TSA family TraF PF13728.1 KND91014.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein MFS_1 PF07690.11 KND91015.1 - 3.8e-31 108.0 56.6 1.9e-29 102.5 39.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KND91015.1 - 1.3e-05 23.9 3.2 1.3e-05 23.9 2.2 3.5 1 1 2 3 3 3 3 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KND91016.1 - 1.8e-39 135.5 43.0 1.8e-39 135.5 29.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND91016.1 - 4.3 5.8 37.3 13 4.1 25.8 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter GMC_oxred_N PF00732.14 KND91018.1 - 2.6e-25 89.1 1.1 9.5e-23 80.7 0.7 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND91018.1 - 5.2e-22 78.6 0.0 9.2e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DUF1399 PF07173.7 KND91019.1 - 2.8e-18 66.5 5.1 4.7e-16 59.3 0.3 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) FAD_binding_2 PF00890.19 KND91020.1 - 0.00024 20.0 0.0 0.00027 19.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND91020.1 - 0.00071 19.5 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND91020.1 - 0.0012 17.8 0.1 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND91020.1 - 0.002 18.0 0.1 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND91020.1 - 0.0023 16.9 0.1 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KND91020.1 - 0.0034 16.5 0.1 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND91020.1 - 0.0069 14.9 0.0 0.0082 14.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KND91020.1 - 0.013 14.6 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KND91020.1 - 0.066 12.0 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KND91020.1 - 0.15 11.1 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Bac_luciferase PF00296.15 KND91022.1 - 8.4e-56 189.3 1.2 1.4e-55 188.5 0.9 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.7 KND91022.1 - 0.0018 17.9 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Asp PF00026.18 KND91023.1 - 1.5e-68 231.4 9.0 1.8e-68 231.1 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND91023.1 - 9e-09 35.4 0.7 3.1e-08 33.7 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND91023.1 - 5.7e-06 26.7 1.9 0.0044 17.4 0.4 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KND91023.1 - 0.018 14.5 0.1 0.059 12.9 0.0 1.9 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Hist_deacetyl PF00850.14 KND91024.1 - 1.8e-79 267.2 0.0 3.6e-79 266.2 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.7 KND91025.1 - 6.8e-96 321.2 0.0 8.4e-96 320.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KND91025.1 - 0.0014 18.9 0.4 0.021 15.2 0.0 2.8 4 0 0 4 4 4 1 Replication protein A C terminal B-block_TFIIIC PF04182.7 KND91025.1 - 0.0024 17.6 0.1 0.0063 16.3 0.0 1.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_36 PF13730.1 KND91025.1 - 0.0042 17.1 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MARVEL PF01284.18 KND91026.1 - 0.11 12.2 16.6 1.7 8.4 0.9 2.9 2 1 0 2 2 2 0 Membrane-associating domain DUF3188 PF11384.3 KND91026.1 - 0.17 11.4 1.4 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Flavi_NS4A PF01350.12 KND91026.1 - 0.3 10.6 3.4 0.6 9.6 2.3 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Pkinase PF00069.20 KND91027.1 - 1.2e-69 234.4 0.0 1.7e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91027.1 - 5.9e-33 114.0 0.0 4.1e-31 107.9 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND91027.1 - 0.007 15.3 1.8 0.6 9.0 0.0 2.6 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 KND91027.1 - 0.0074 15.6 0.5 0.015 14.6 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Pro_isomerase PF00160.16 KND91028.1 - 1.2e-38 132.7 0.2 3.7e-38 131.1 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 KND91029.1 - 7.2e-46 155.1 0.1 1e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KND91029.1 - 0.00084 18.1 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Metallophos PF00149.23 KND91030.1 - 1.3e-06 27.9 3.1 4.2e-06 26.3 2.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF221 PF02714.10 KND91032.1 - 6.2e-91 304.6 18.6 1.2e-90 303.6 12.9 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND91032.1 - 2.1e-43 147.6 0.5 2.1e-43 147.6 0.3 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KND91032.1 - 8.4e-22 76.8 0.1 2e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KND91032.1 - 3.9e-12 46.5 4.4 9.5e-07 29.2 1.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KND91032.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupredoxin_1 PF13473.1 KND91033.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 KND91033.1 - 0.0012 18.9 0.0 0.0034 17.5 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 KND91033.1 - 0.083 12.6 0.7 0.93 9.3 0.5 2.3 1 1 0 1 1 1 0 Plastocyanin-like domain DUF1517 PF07466.6 KND91033.1 - 3 6.7 8.4 2.1 7.2 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) NUDIX PF00293.23 KND91035.1 - 5.5e-13 48.7 0.0 7.4e-12 45.0 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain Pro_dh PF01619.13 KND91036.1 - 1.1e-38 133.0 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.14 KND91037.1 - 0.017 15.1 6.5 0.031 14.3 4.5 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family NACHT PF05729.7 KND91038.1 - 1.3e-22 80.2 0.1 1.6e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KND91038.1 - 4.6e-05 23.5 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain HET-s_218-289 PF11558.3 KND91038.1 - 0.0024 17.8 0.5 0.0053 16.7 0.3 1.6 1 0 0 1 1 1 1 Het-s 218-289 AAA_19 PF13245.1 KND91038.1 - 0.0028 17.3 0.0 0.007 16.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KND91038.1 - 0.0096 15.9 0.1 0.022 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AFG1_ATPase PF03969.11 KND91038.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase AAA_11 PF13086.1 KND91038.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND91038.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KND91038.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KND91038.1 - 0.038 13.8 0.0 0.081 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Neil1-DNA_bind PF09292.5 KND91038.1 - 0.042 13.6 0.4 0.092 12.5 0.3 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind UPF0079 PF02367.12 KND91038.1 - 0.043 13.4 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KND91038.1 - 0.07 13.3 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KND91038.1 - 0.08 12.6 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 KND91038.1 - 0.089 11.7 0.1 9.2 5.1 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain REV PF00424.13 KND91039.1 - 0.14 12.0 0.2 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) IDO PF01231.13 KND91040.1 - 1e-141 472.2 0.0 1.2e-141 471.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KND91040.1 - 0.00059 18.4 0.0 0.042 12.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) CbtB PF09489.5 KND91040.1 - 0.046 13.6 0.2 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) RAMP PF04901.8 KND91040.1 - 0.13 12.0 0.2 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Receptor activity modifying family Aminotran_5 PF00266.14 KND91041.1 - 7.4e-09 34.8 0.0 1.6e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KND91041.1 - 0.024 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 KND91042.1 - 8.1e-11 41.2 0.0 1.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91042.1 - 1.6e-05 24.7 12.0 2.7e-05 23.9 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 KND91043.1 - 2.2e-113 378.3 0.2 3.5e-113 377.7 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 KND91043.1 - 0.0082 15.9 1.4 0.021 14.6 1.0 1.6 1 0 0 1 1 1 1 Herpesvirus UL14-like protein Fungal_trans PF04082.13 KND91044.1 - 4e-12 45.5 0.0 8e-12 44.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91044.1 - 2.9e-08 33.4 7.0 5e-08 32.7 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAD PF05557.8 KND91044.1 - 0.43 8.6 0.2 0.8 7.7 0.0 1.4 2 0 0 2 2 2 0 Mitotic checkpoint protein CGI-121 PF08617.5 KND91045.1 - 6.3e-50 168.9 0.0 7.3e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MlrC_C PF07171.7 KND91045.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 MlrC C-terminus ADH_zinc_N PF00107.21 KND91046.1 - 1e-07 31.5 0.5 2.4e-07 30.3 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND91046.1 - 0.00011 21.9 0.0 0.00066 19.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND91046.1 - 0.00039 21.3 0.0 0.00089 20.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SRF-TF PF00319.13 KND91047.1 - 6.3e-23 79.7 0.1 1e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) His_Phos_2 PF00328.17 KND91048.1 - 3.4e-30 105.5 0.0 4.4e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.19 KND91049.1 - 1.7e-121 405.9 22.7 2e-121 405.7 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91049.1 - 8.8e-21 73.9 35.2 8.8e-15 54.2 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fasciclin PF02469.17 KND91051.1 - 0.003 17.5 0.0 0.0058 16.6 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain FAD_binding_2 PF00890.19 KND91052.1 - 8.1e-83 278.5 0.9 1e-82 278.2 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KND91052.1 - 1.9e-20 72.4 1.9 2.2e-19 68.9 0.0 3.4 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KND91052.1 - 2.6e-13 49.6 1.6 1e-12 47.6 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KND91052.1 - 1.7e-09 37.2 0.3 5.5e-09 35.6 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND91052.1 - 7.6e-09 35.7 0.0 6.4e-07 29.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND91052.1 - 2.6e-08 33.7 0.7 2.9e-07 30.3 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND91052.1 - 4.6e-05 22.6 0.6 0.012 14.6 0.2 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KND91052.1 - 0.0015 17.4 3.3 0.13 11.0 0.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KND91052.1 - 0.0026 16.2 7.4 0.01 14.3 0.3 3.2 3 1 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 KND91052.1 - 0.0037 16.3 0.2 0.94 8.4 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KND91052.1 - 0.0072 15.4 4.9 0.07 12.1 3.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KND91052.1 - 0.0093 16.3 3.2 0.5 10.8 0.4 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND91052.1 - 0.022 14.7 1.3 0.11 12.5 0.9 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MBOAT PF03062.14 KND91053.1 - 2.1e-44 151.9 18.1 4.8e-44 150.7 12.5 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3419 PF11899.3 KND91055.1 - 2.3e-153 510.4 0.1 3.1e-153 509.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KND91055.1 - 2.7e-09 36.9 0.0 2.7e-07 30.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND91055.1 - 8.7e-09 35.7 0.0 4.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91055.1 - 8.7e-08 32.7 0.0 4.5e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND91055.1 - 5.4e-07 29.3 0.0 6.6e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND91055.1 - 9.5e-07 28.8 0.0 8.7e-05 22.5 0.0 3.2 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91055.1 - 2.3e-06 27.9 0.0 0.013 15.9 0.0 3.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND91055.1 - 2.4e-05 23.5 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KND91055.1 - 0.00016 21.9 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND91055.1 - 0.00049 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_16 PF13191.1 KND91055.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Myc_N PF01056.13 KND91057.1 - 0.043 12.9 2.6 0.074 12.2 1.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF1656 PF07869.7 KND91057.1 - 0.16 11.7 1.7 0.3 10.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Sigma70_ner PF04546.8 KND91057.1 - 0.3 10.6 5.7 0.42 10.2 4.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 KND91057.1 - 0.52 9.9 4.5 0.81 9.3 3.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 KND91057.1 - 0.59 9.6 5.0 0.88 9.0 3.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KND91057.1 - 8.3 6.8 10.0 0.58 10.5 3.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bromodomain PF00439.20 KND91058.1 - 6.5e-26 90.0 0.4 1.4e-25 88.9 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KND91058.1 - 3.1e-09 36.8 0.1 6.8e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND91058.1 - 7.4e-09 35.5 0.0 1.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KND91058.1 - 0.017 15.2 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_2 PF00703.16 KND91059.1 - 2.6e-12 47.1 0.0 5.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KND91059.1 - 1.8e-08 34.1 0.0 9.7e-08 31.7 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KND91059.1 - 3.3e-06 26.2 0.1 5.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_S8 PF00082.17 KND91060.1 - 1.5e-39 135.8 18.0 2.1e-39 135.3 12.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND91060.1 - 3.3e-16 59.5 0.0 8e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 GMC_oxred_N PF00732.14 KND91062.1 - 1.7e-32 112.7 0.0 8.1e-29 100.6 0.0 2.6 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KND91062.1 - 1.3e-30 106.5 0.2 2.1e-30 105.9 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KND91062.1 - 0.0058 16.5 0.0 0.096 12.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND91062.1 - 0.0092 14.8 0.2 0.018 13.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND91062.1 - 0.012 15.6 0.1 0.034 14.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND91062.1 - 0.024 13.5 0.1 0.29 9.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KND91062.1 - 0.048 13.0 0.2 0.091 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KND91062.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KND91062.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF59 PF01883.14 KND91063.1 - 1.3e-05 25.0 0.1 5.5e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function DUF59 DHDPS PF00701.17 KND91064.1 - 2.8e-48 164.0 0.0 3.5e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KND91064.1 - 0.00012 21.3 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_M1 PF01433.15 KND91065.1 - 5.1e-10 39.0 0.2 0.0087 15.1 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 KND91065.1 - 0.023 14.9 0.4 3.5 7.9 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats NMT_C PF02799.10 KND91066.1 - 5.1e-78 260.8 0.1 7.4e-78 260.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KND91066.1 - 5e-73 244.0 0.2 1.2e-72 242.8 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KND91066.1 - 0.0001 22.1 0.1 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PAH PF02671.16 KND91067.1 - 1.9e-44 149.0 1.3 2.7e-18 65.3 0.5 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KND91067.1 - 7.1e-40 134.8 0.4 2.7e-39 132.9 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor LIM_bind PF01803.11 KND91068.1 - 1 8.4 3.4 2 7.4 2.4 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Abhydrolase_5 PF12695.2 KND91069.1 - 1.8e-16 60.2 0.3 3.1e-16 59.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND91069.1 - 2.3e-14 53.8 3.5 4.3e-14 52.9 2.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND91069.1 - 1.3e-07 31.4 0.1 3.7e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KND91069.1 - 1e-05 25.2 0.1 5.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 KND91069.1 - 4.8e-05 23.0 1.4 8e-05 22.3 0.9 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KND91069.1 - 0.0067 15.8 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Cutinase PF01083.17 KND91069.1 - 0.017 14.8 0.1 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_2 PF02230.11 KND91069.1 - 0.21 10.9 0.4 0.75 9.1 0.1 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TLD PF07534.11 KND91070.1 - 3.1e-30 104.9 0.0 6.3e-30 103.9 0.0 1.5 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 KND91070.1 - 9.4e-11 41.7 0.2 3.1e-10 40.1 0.1 2.0 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal VIT1 PF01988.14 KND91071.1 - 7.5e-58 195.5 4.3 9e-58 195.2 3.0 1.1 1 0 0 1 1 1 1 VIT family Mid2 PF04478.7 KND91071.1 - 0.0038 16.6 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor ATP_synt_I PF03899.10 KND91071.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.9 2 1 0 3 3 3 0 ATP synthase I chain ZZ PF00569.12 KND91072.1 - 6.7e-11 41.5 7.9 1.2e-10 40.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KND91072.1 - 3.4e-07 29.0 2.9 5e-05 22.3 0.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 KND91072.1 - 9.1e-07 28.9 10.8 6.1e-06 26.2 2.3 4.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 KND91072.1 - 0.0002 20.8 5.7 0.086 12.4 0.1 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KND91072.1 - 0.00064 19.3 0.2 0.00064 19.3 0.1 4.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_4 PF12763.2 KND91072.1 - 0.016 14.9 0.1 0.063 13.0 0.0 2.1 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand C1_3 PF07649.7 KND91072.1 - 0.022 14.8 9.1 0.039 13.9 6.3 1.4 1 0 0 1 1 1 0 C1-like domain Abhydrolase_6 PF12697.2 KND91073.1 - 2.5e-17 63.5 6.4 4.4e-17 62.7 4.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND91073.1 - 5.7e-06 26.1 2.2 1.7e-05 24.5 0.4 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ada_Zn_binding PF02805.11 KND91074.1 - 1.5e-29 101.3 7.4 1.5e-29 101.3 5.2 1.5 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_AraC PF00165.18 KND91074.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KND91074.1 - 4.7e-06 26.6 0.1 9.2e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 KND91074.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain GTP_EFTU PF00009.22 KND91075.1 - 1.8e-42 144.9 0.0 2.8e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KND91075.1 - 2.9e-25 88.1 0.0 6.7e-17 61.1 0.0 2.9 2 0 0 2 2 2 2 Elongation factor G, domain IV EFG_C PF00679.19 KND91075.1 - 8.3e-18 64.0 0.0 2.1e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND91075.1 - 2.4e-08 33.9 0.3 7.1e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KND91075.1 - 1.1e-07 31.5 0.1 5.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KND91075.1 - 0.0001 22.2 0.1 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND91075.1 - 0.0021 18.5 0.1 0.0049 17.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PX PF00787.19 KND91076.1 - 3.3e-21 75.1 0.0 5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 PX domain IQ PF00612.22 KND91077.1 - 8.7e-05 21.8 0.3 8.7e-05 21.8 0.2 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF3329 PF11808.3 KND91078.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) SKG6 PF08693.5 KND91078.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Grp1_Fun34_YaaH PF01184.14 KND91079.1 - 2.2e-82 275.4 14.2 2.6e-82 275.1 9.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.11 KND91080.1 - 1.5e-28 99.5 52.7 2.2e-17 62.8 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KND91081.1 - 1.7e-19 69.6 1.8 3.8e-19 68.5 1.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91081.1 - 1.3e-06 28.1 9.9 1.3e-06 28.1 6.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBN_N PF03810.14 KND91083.1 - 7.6e-13 48.1 0.0 6.3e-12 45.2 0.0 2.8 1 1 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KND91083.1 - 4.4e-05 23.4 2.3 0.001 18.9 0.1 3.7 3 1 1 4 4 4 1 Exportin 1-like protein Cse1 PF08506.5 KND91083.1 - 0.00012 20.8 0.1 0.015 13.8 0.0 2.3 2 0 0 2 2 2 2 Cse1 Fungal_trans PF04082.13 KND91084.1 - 1.9e-09 36.7 0.0 3.7e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91084.1 - 1.4e-08 34.4 5.8 2.6e-08 33.6 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spherulin4 PF12138.3 KND91085.1 - 3.5e-66 223.2 0.0 4e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Epimerase PF01370.16 KND91086.1 - 6.1e-35 120.7 0.0 1.5e-33 116.2 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KND91086.1 - 1.4e-15 56.9 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KND91086.1 - 6.2e-06 25.1 0.5 0.015 14.0 0.0 2.6 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KND91086.1 - 4.3e-05 22.5 0.1 0.00021 20.2 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KND91086.1 - 4.6e-05 22.4 0.0 9.8e-05 21.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KND91086.1 - 0.0022 18.0 0.3 0.43 10.5 0.0 2.8 3 0 0 3 3 3 1 NADH(P)-binding adh_short PF00106.20 KND91086.1 - 0.0033 17.3 0.5 0.099 12.5 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase DAO PF01266.19 KND91086.1 - 0.02 13.8 0.1 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KND91086.1 - 0.032 13.6 0.2 0.066 12.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 KND91086.1 - 0.038 13.6 0.5 0.67 9.6 0.4 2.4 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 KND91086.1 - 0.11 11.3 0.1 0.48 9.2 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.13 KND91086.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Na_H_Exchanger PF00999.16 KND91087.1 - 5.8e-66 222.5 43.2 8.5e-66 222.0 29.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UPF0228 PF05727.6 KND91088.1 - 0.12 12.0 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0228) NIF PF03031.13 KND91091.1 - 2.9e-27 95.3 0.2 1.3e-23 83.4 0.1 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2077 PF09850.4 KND91091.1 - 0.048 13.0 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF605 PF04652.11 KND91092.1 - 3e-77 260.5 14.3 2e-72 244.7 7.2 2.0 2 0 0 2 2 2 2 Vta1 like Thioredoxin PF00085.15 KND91094.1 - 6.6e-31 106.0 0.0 8.6e-25 86.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KND91094.1 - 1.1e-08 35.2 2.3 0.0021 18.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND91094.1 - 2.7e-06 27.4 0.0 0.019 15.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like TraF PF13728.1 KND91094.1 - 0.0076 15.7 3.5 2.7 7.4 0.0 3.2 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 KND91094.1 - 0.0082 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KND91094.1 - 0.018 14.8 0.2 0.8 9.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.1 KND91094.1 - 0.058 12.9 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin BK_channel_a PF03493.13 KND91094.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit RNase_PH PF01138.16 KND91095.1 - 3.6e-36 124.4 0.2 5.7e-36 123.7 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SDH_alpha PF03313.10 KND91095.1 - 0.017 14.1 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain RNase_PH_C PF03725.10 KND91095.1 - 0.052 13.4 0.1 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 SAS4 PF15460.1 KND91096.1 - 5.9e-36 122.3 0.2 1.9e-35 120.7 0.1 1.9 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 CamS PF07537.6 KND91096.1 - 0.033 13.2 0.3 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 CamS sex pheromone cAM373 precursor CDC45 PF02724.9 KND91096.1 - 0.63 8.0 10.7 0.93 7.4 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Adaptin_binding PF10199.4 KND91096.1 - 1.3 9.3 14.5 0.16 12.2 6.6 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SAPS PF04499.10 KND91096.1 - 4.8 5.6 6.6 11 4.4 4.1 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Arginosuc_synth PF00764.14 KND91097.1 - 1e-142 475.7 0.0 1.2e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 KND91097.1 - 0.0046 16.4 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KND91097.1 - 0.054 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ubiquitin PF00240.18 KND91098.1 - 4.1e-19 67.7 0.1 7.1e-19 66.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KND91098.1 - 3.5e-08 33.0 0.0 3.5e-08 33.0 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 KND91098.1 - 7.6e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KND91098.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KND91098.1 - 0.066 13.4 0.4 0.37 11.0 0.3 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 KND91098.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad4 PF03835.10 KND91099.1 - 5.2e-15 55.1 5.3 9.8e-15 54.2 3.7 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KND91099.1 - 1.1e-11 44.9 4.2 4.9e-11 42.8 2.1 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily FKBP_C PF00254.23 KND91100.1 - 2.2e-20 72.4 0.2 4.2e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Polysacc_deac_1 PF01522.16 KND91101.1 - 0.033 13.8 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Glyco_hydro_114 PF03537.8 KND91102.1 - 8.4e-23 79.9 0.1 1.4e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 OppC_N PF12911.2 KND91102.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2839 PF10999.3 KND91102.1 - 0.098 12.7 0.1 0.48 10.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DJ-1_PfpI_N PF13587.1 KND91102.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family PMSR PF01625.16 KND91103.1 - 6.4e-58 195.0 0.1 7.9e-58 194.7 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Rb_C PF08934.5 KND91103.1 - 0.32 10.6 1.0 0.5 9.9 0.7 1.2 1 0 0 1 1 1 0 Rb C-terminal domain cNMP_binding PF00027.24 KND91104.1 - 3e-35 119.9 0.0 9.1e-19 67.0 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Bax1-I PF01027.15 KND91104.1 - 1.6e-29 103.0 8.0 2.3e-29 102.4 5.5 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 LRR_6 PF13516.1 KND91104.1 - 4.9e-12 44.6 5.8 0.092 12.8 0.0 7.5 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.2 KND91104.1 - 2.7e-06 26.9 1.0 6.7e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KND91104.1 - 4.3e-06 26.3 0.6 0.026 14.2 0.1 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KND91104.1 - 1.3e-05 24.6 0.0 0.21 11.2 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KND91104.1 - 1.4e-05 24.5 0.4 1.4e-05 24.5 0.3 3.1 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 KND91104.1 - 0.0075 16.2 5.9 12 6.6 0.0 5.4 4 1 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 KND91104.1 - 0.045 13.7 9.2 7 7.1 0.1 5.8 5 3 0 5 5 5 0 Leucine Rich Repeat Zn_clus PF00172.13 KND91105.1 - 5.7e-09 35.7 8.8 1e-08 34.9 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND91105.1 - 0.0028 16.5 0.0 0.0079 15.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 KND91106.1 - 1.2e-23 84.1 0.6 2.2e-23 83.3 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribophorin_II PF05817.9 KND91106.1 - 3.4e-15 55.3 0.1 5.1e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Abhydrolase_1 PF00561.15 KND91106.1 - 4.7e-15 55.7 0.0 1.1e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND91106.1 - 7.6e-10 38.7 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TgMIC1 PF11476.3 KND91106.1 - 0.017 14.6 0.6 0.1 12.1 0.1 2.4 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF1100 PF06500.6 KND91106.1 - 0.025 13.1 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_4 PF08386.5 KND91106.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.15 KND91106.1 - 0.028 14.6 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase_phd PF10503.4 KND91106.1 - 0.053 12.7 0.1 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase UPF0227 PF05728.7 KND91106.1 - 0.054 13.2 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.13 KND91106.1 - 0.09 12.0 0.0 8.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family HIG_1_N PF04588.8 KND91107.1 - 9.5e-21 73.2 0.2 2.1e-20 72.2 0.2 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Fibrinogen_BP PF08017.6 KND91107.1 - 0.022 13.0 1.6 0.031 12.4 1.1 1.3 1 0 0 1 1 1 0 Fibrinogen binding protein OPA3 PF07047.7 KND91107.1 - 0.022 14.5 0.3 0.034 13.9 0.2 1.6 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) MAS20 PF02064.10 KND91107.1 - 0.13 12.2 0.8 0.26 11.2 0.5 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Gag_p12 PF01141.13 KND91107.1 - 0.75 9.9 3.3 18 5.5 0.2 2.8 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 ANTAR PF03861.9 KND91108.1 - 0.12 11.9 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 ANTAR domain DUF3129 PF11327.3 KND91109.1 - 1.3e-56 191.3 12.0 2.1e-56 190.6 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Collagen PF01391.13 KND91109.1 - 1.4e-06 27.7 67.7 3.5e-05 23.2 21.3 3.1 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Pkinase PF00069.20 KND91111.1 - 3e-38 131.4 0.0 4.4e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91111.1 - 4.6e-20 71.7 0.0 1.5e-19 70.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND91111.1 - 6.3e-06 25.3 0.0 1.7e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND91111.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.11 KND91111.1 - 0.03 14.3 0.1 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Ctr PF04145.10 KND91112.1 - 1.9e-42 144.7 0.5 2.3e-42 144.4 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Abhydrolase_4 PF08386.5 KND91113.1 - 9.4e-14 51.1 0.0 2.6e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KND91113.1 - 2.7e-08 33.6 0.0 9.7e-07 28.5 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND91113.1 - 4.9e-05 23.3 4.4 4.9e-05 23.3 3.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND91113.1 - 0.0014 18.4 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Amino_oxidase PF01593.19 KND91114.1 - 1.5e-28 100.0 0.6 1.2e-20 74.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND91114.1 - 7.6e-09 35.4 0.9 1.9e-08 34.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND91114.1 - 1.8e-07 31.4 0.2 1.4e-06 28.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND91114.1 - 4.1e-07 29.2 0.6 1.7e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KND91114.1 - 1.8e-06 27.2 0.0 3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KND91114.1 - 2.7e-06 26.5 0.2 4.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND91114.1 - 2.7e-06 26.1 1.0 3.4e-05 22.5 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KND91114.1 - 5e-05 22.5 0.1 7.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KND91114.1 - 0.00017 20.5 0.3 0.00096 18.1 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KND91114.1 - 0.00026 20.0 0.6 0.057 12.3 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 KND91114.1 - 0.00027 20.1 1.3 0.00037 19.6 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND91114.1 - 0.00037 20.4 0.1 0.0013 18.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND91114.1 - 0.0031 17.8 0.3 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND91114.1 - 0.011 15.5 0.3 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KND91114.1 - 0.027 14.0 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KND91114.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 KND91114.1 - 0.19 10.6 0.0 7.6 5.3 0.0 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Sugar_tr PF00083.19 KND91115.1 - 3.5e-44 151.1 19.0 4.5e-44 150.7 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91115.1 - 6.1e-18 64.6 24.3 1e-17 63.9 16.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Hemerythrin PF01814.18 KND91116.1 - 8.9e-11 42.0 2.2 1.2e-10 41.6 1.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PALP PF00291.20 KND91117.1 - 1.3e-72 244.6 0.7 1.7e-72 244.2 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KND91117.1 - 7.5e-41 137.6 0.0 1.2e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF2465 PF10239.4 KND91117.1 - 0.031 13.4 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) Glyco_hydro_76 PF03663.9 KND91118.1 - 2.6e-25 89.6 4.1 2.1e-23 83.3 0.4 3.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 NPR2 PF06218.6 KND91119.1 - 3.7e-113 378.4 0.0 8e-97 324.6 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DUF3650 PF12368.3 KND91119.1 - 0.048 13.1 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) tRNA-synt_1b PF00579.20 KND91120.1 - 2.8e-55 187.5 0.0 1.4e-53 181.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Maf PF02545.9 KND91121.1 - 4e-23 81.5 0.1 2e-15 56.4 0.0 2.1 1 1 1 2 2 2 2 Maf-like protein tRNA-synt_2b PF00587.20 KND91122.1 - 2.1e-49 167.4 0.0 2.9e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND91122.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain CybS PF05328.7 KND91123.1 - 1e-49 167.5 0.0 1.3e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KND91123.1 - 0.084 12.7 0.4 1.3 8.8 0.3 2.1 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FHA PF00498.21 KND91124.1 - 1.7e-08 34.4 0.0 4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KND91124.1 - 0.18 12.0 0.3 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DIOX_N PF14226.1 KND91125.1 - 1.4e-21 77.1 0.1 2.5e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND91125.1 - 6.5e-16 58.4 0.0 2.2e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Scytalone_dh PF02982.9 KND91126.1 - 2.1e-43 147.6 0.7 2.3e-43 147.5 0.5 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KND91126.1 - 0.019 14.8 0.9 0.024 14.5 0.6 1.1 1 0 0 1 1 1 0 SnoaL-like domain adh_short_C2 PF13561.1 KND91127.1 - 1.7e-29 103.2 0.0 2.1e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND91127.1 - 2.5e-24 86.0 1.2 3.9e-24 85.4 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND91127.1 - 4e-07 29.8 0.8 5.7e-07 29.3 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND91127.1 - 0.0095 15.9 1.2 0.014 15.3 0.8 1.6 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KND91127.1 - 0.022 13.8 0.1 0.032 13.3 0.1 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2059 PF09832.4 KND91127.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) Eno-Rase_NADH_b PF12242.3 KND91127.1 - 0.11 12.3 1.3 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF971 PF06155.7 KND91127.1 - 0.11 12.8 0.1 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Epimerase PF01370.16 KND91127.1 - 0.12 11.8 0.0 0.68 9.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cys_rich_CWC PF14375.1 KND91127.1 - 0.41 10.6 3.6 0.24 11.3 1.1 1.7 2 0 0 2 2 2 0 Cysteine-rich CWC ketoacyl-synt PF00109.21 KND91128.1 - 2.5e-70 236.8 0.0 4.5e-70 236.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND91128.1 - 7.2e-46 156.9 0.7 3.4e-45 154.7 0.0 2.3 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KND91128.1 - 2e-32 111.5 0.7 1.1e-31 109.0 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KND91128.1 - 1.4e-09 38.0 0.2 3.6e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KND91128.1 - 5.6e-05 22.2 0.1 0.00015 20.8 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain TSC22 PF01166.13 KND91128.1 - 0.063 13.2 0.0 6 6.9 0.0 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Pkinase PF00069.20 KND91129.1 - 3.3e-08 32.9 0.0 0.00086 18.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND91129.1 - 0.01 14.9 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase adh_short PF00106.20 KND91130.1 - 2.6e-30 105.5 1.1 3.3e-30 105.1 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND91130.1 - 9.9e-30 104.0 0.2 1.2e-29 103.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND91130.1 - 8e-13 48.4 0.6 1.1e-12 47.9 0.4 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND91130.1 - 0.0012 17.7 0.6 0.0017 17.3 0.4 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KND91130.1 - 0.002 17.6 0.2 0.0068 15.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KND91130.1 - 0.043 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CABS1 PF15367.1 KND91130.1 - 0.061 12.1 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 3HCDH_N PF02737.13 KND91130.1 - 0.088 12.4 2.2 0.12 12.0 0.5 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B PF00753.22 KND91131.1 - 8.9e-20 71.1 1.1 1.5e-19 70.4 0.7 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND91131.1 - 0.0062 16.0 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_10 PF13460.1 KND91133.1 - 4e-16 59.5 0.0 5.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KND91133.1 - 8.9e-08 31.6 0.1 1.8e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 KND91133.1 - 4.9e-05 22.8 0.1 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND91133.1 - 0.0041 15.8 0.0 0.0072 15.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KND91133.1 - 0.005 15.7 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KND91133.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KND91133.1 - 0.021 15.2 0.0 0.044 14.2 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KND91133.1 - 0.059 13.1 0.1 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus KR PF08659.5 KND91133.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 KND91133.1 - 0.1 11.5 0.1 0.27 10.1 0.1 1.7 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.20 KND91133.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase MitMem_reg PF13012.1 KND91134.1 - 5e-26 91.0 1.6 1.2e-25 89.8 1.1 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KND91134.1 - 1.1e-15 57.3 0.0 2.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Asp PF00026.18 KND91135.1 - 6e-31 107.8 0.0 7.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease adh_short PF00106.20 KND91136.1 - 3.4e-19 69.3 2.8 4.8e-19 68.8 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND91136.1 - 3e-09 36.7 2.3 7.1e-09 35.5 1.6 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KND91136.1 - 0.0014 17.4 0.1 0.0044 15.7 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND91136.1 - 0.0033 17.4 0.6 0.032 14.2 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KND91136.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank PF00023.25 KND91136.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ras PF00071.17 KND91137.1 - 1.1e-42 145.1 0.0 2.2e-42 144.2 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KND91137.1 - 1.6e-14 54.3 0.0 2.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND91137.1 - 6.9e-11 41.7 0.0 3.9e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.4 KND91137.1 - 0.00023 20.6 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KND91137.1 - 0.00098 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND91137.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KND91137.1 - 0.0022 17.8 0.0 0.0074 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KND91137.1 - 0.0037 17.5 0.3 0.054 13.7 0.2 2.2 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 KND91137.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KND91137.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND91137.1 - 0.032 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KND91137.1 - 0.04 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KND91137.1 - 0.046 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KND91137.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 KND91137.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Malic_M PF03949.10 KND91138.1 - 9.6e-75 251.4 0.0 1.3e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KND91138.1 - 2.1e-63 213.1 0.0 3.5e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2413 PF10310.4 KND91139.1 - 1.2e-136 456.1 0.0 1.5e-136 455.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ribosomal_L14 PF00238.14 KND91141.1 - 2.8e-26 91.6 0.0 5.2e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L14p/L23e Ssu72 PF04722.8 KND91142.1 - 6e-87 290.0 0.0 7e-87 289.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein NYN_YacP PF05991.6 KND91142.1 - 0.039 13.7 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 YacP-like NYN domain GIT_SHD PF08518.6 KND91143.1 - 2.9e-20 71.3 5.0 6.1e-14 51.0 0.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT CENP-K PF11802.3 KND91143.1 - 0.02 14.1 13.7 0.051 12.7 9.5 1.7 1 0 0 1 1 1 0 Centromere-associated protein K FUSC PF04632.7 KND91143.1 - 0.31 9.4 9.2 0.56 8.5 6.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Filament PF00038.16 KND91143.1 - 1.5 8.2 34.4 2 7.7 8.7 2.4 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 KND91143.1 - 2.4 6.4 22.5 1.5 7.2 13.0 2.3 2 1 0 2 2 2 0 AAA domain APG6 PF04111.7 KND91143.1 - 4.9 6.0 33.1 0.062 12.3 14.5 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 CHD5 PF04420.9 KND91143.1 - 5.4 6.6 4.7 19 4.9 3.2 1.9 1 0 0 1 1 1 0 CHD5-like protein JmjC PF02373.17 KND91144.1 - 4.9e-19 68.6 0.0 9.2e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF4448 PF14610.1 KND91145.1 - 2e-19 69.8 0.0 2.6e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Peptidase_M28 PF04389.12 KND91146.1 - 5.8e-16 58.7 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KND91146.1 - 1.6e-13 50.2 0.0 4.1e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KND91146.1 - 6.8e-07 28.9 0.1 3.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 KND91146.1 - 0.0043 16.3 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 Nicastrin NAD_binding_1 PF00175.16 KND91149.1 - 2.3e-31 108.5 0.0 6.1e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KND91149.1 - 1.7e-19 69.7 0.0 2.9e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KND91149.1 - 1.4e-09 37.9 0.0 8.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain SH3_1 PF00018.23 KND91150.1 - 7.8e-09 34.7 0.0 1.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND91150.1 - 1.1e-08 34.5 0.1 2.6e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND91150.1 - 2e-06 27.1 0.1 5.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain DUF3716 PF12511.3 KND91152.1 - 9.6e-09 34.7 2.1 1.9e-08 33.8 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Sugar_tr PF00083.19 KND91153.1 - 9e-109 364.0 17.2 1.1e-108 363.7 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91153.1 - 3.1e-23 82.0 28.4 9.8e-14 50.8 1.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Rif1_N PF12231.3 KND91154.1 - 4e-133 443.9 2.6 4e-133 443.9 1.8 2.0 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal LRR_4 PF12799.2 KND91155.1 - 2e-39 132.5 23.8 3e-11 42.6 1.7 6.1 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND91155.1 - 2.2e-28 97.7 65.5 6.1e-08 32.2 2.4 5.3 2 1 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 KND91155.1 - 1.8e-11 42.3 22.3 0.39 10.9 0.1 10.3 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_9 PF14580.1 KND91155.1 - 5.1e-11 42.4 9.3 2.6e-06 27.1 1.1 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KND91155.1 - 1.2e-07 30.7 19.0 1 9.8 0.1 9.0 9 0 0 9 9 9 2 Leucine rich repeat LRR_6 PF13516.1 KND91155.1 - 2.2e-07 30.2 27.1 0.039 14.0 0.4 9.5 6 3 3 9 9 9 2 Leucine Rich repeat BTB PF00651.26 KND91156.1 - 5.4e-08 32.8 0.0 2.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Abhydrolase_5 PF12695.2 KND91157.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND91157.1 - 1.4e-07 31.6 1.9 2e-07 31.1 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KND91157.1 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 KND91157.1 - 0.0098 15.1 0.0 0.91 8.6 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 KND91157.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L18ae PF01775.12 KND91158.1 - 1e-56 190.1 0.6 1.4e-56 189.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 KND91159.1 - 1.1e-09 38.4 0.0 4e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.1 KND91159.1 - 0.023 14.3 0.2 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 TPR repeat Ric8 PF10165.4 KND91160.1 - 2.5e-120 402.3 0.1 2.9e-120 402.1 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Acetyltransf_3 PF13302.1 KND91161.1 - 6.3e-33 113.9 0.1 7.9e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND91161.1 - 0.0028 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND91161.1 - 0.0055 16.7 0.3 0.25 11.4 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND91161.1 - 0.046 13.8 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND91161.1 - 0.093 12.6 0.1 0.26 11.1 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4380 PF14315.1 KND91162.1 - 0.0077 15.4 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4380) HMG_box PF00505.14 KND91163.1 - 9.5e-08 32.2 0.4 2.6e-07 30.7 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND91163.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 2.5 3 0 0 3 3 3 1 HMG-box domain Het-C PF07217.6 KND91164.1 - 4.6e-259 860.7 0.0 6.5e-259 860.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Gluconate_2-dh3 PF13618.1 KND91164.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Ada3 PF10198.4 KND91165.1 - 4.8e-43 146.0 0.0 1.3e-42 144.6 0.0 1.8 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.15 KND91166.1 - 4.1e-62 210.7 2.2 5.2e-62 210.4 1.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KND91166.1 - 1e-52 177.3 1.9 1.8e-52 176.5 1.3 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 KND91166.1 - 1.5e-12 47.3 0.0 3.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KND91166.1 - 1.4e-06 28.0 3.8 3.6e-06 26.6 2.7 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KND91166.1 - 8.5e-06 25.2 0.4 8.5e-06 25.2 0.3 2.0 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 KND91166.1 - 0.032 13.7 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase VWA_3 PF13768.1 KND91167.1 - 1e-24 87.0 0.0 1.8e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KND91167.1 - 6.7e-12 45.8 0.0 2e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KND91167.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KND91167.1 - 0.00045 20.0 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 KND91167.1 - 0.0041 16.3 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 KND91167.1 - 0.089 12.8 0.1 0.34 10.9 0.0 2.1 2 1 0 2 2 2 0 VWA-like domain (DUF2201) VIT PF08487.5 KND91168.1 - 3.9e-19 68.4 0.0 6.7e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Transglut_prok PF09017.5 KND91169.1 - 6.2 5.8 5.7 12 4.8 0.8 2.1 2 0 0 2 2 2 0 Microbial transglutaminase zf-RING_2 PF13639.1 KND91170.1 - 3.8e-11 42.6 7.1 1e-10 41.2 4.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KND91170.1 - 3.4e-06 26.6 7.3 6.9e-06 25.6 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND91170.1 - 7e-06 26.0 4.4 2.5e-05 24.2 3.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND91170.1 - 0.00011 22.1 7.8 0.00024 21.0 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND91170.1 - 0.00034 20.2 7.4 0.00067 19.3 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KND91170.1 - 0.0067 16.2 3.7 0.021 14.6 2.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KND91170.1 - 0.064 12.9 9.3 0.15 11.7 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3609 PF12259.3 KND91170.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Rtf2 PF04641.7 KND91170.1 - 0.56 9.3 2.1 0.67 9.0 0.7 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 KND91170.1 - 0.79 9.6 9.5 1.7 8.5 6.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KND91170.1 - 4.9 6.9 7.9 12 5.7 5.5 1.7 1 0 0 1 1 1 0 PHD-finger Glycoprotein_B PF00606.13 KND91171.1 - 1.7 6.5 2.3 1.5 6.7 0.6 1.5 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B IMS PF00817.15 KND91172.1 - 1.1e-43 148.6 0.6 2.1e-43 147.6 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KND91172.1 - 3.4e-16 59.3 0.0 8.5e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KND91172.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif FKBP_C PF00254.23 KND91173.1 - 3.5e-34 116.7 0.0 5.1e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box PF00646.28 KND91175.1 - 1.7e-06 27.5 0.2 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KND91175.1 - 8.5e-05 22.2 0.2 0.00063 19.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like FAM117 PF15388.1 KND91175.1 - 0.0047 16.2 3.0 0.0066 15.7 2.1 1.1 1 0 0 1 1 1 1 Protein Family FAM117 APC_CDC26 PF10471.4 KND91175.1 - 0.12 13.0 7.2 0.3 11.8 5.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PRANC PF09372.5 KND91175.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 PRANC domain Methyltransf_24 PF13578.1 KND91176.1 - 1.8e-08 35.1 0.0 4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91176.1 - 0.00011 22.7 0.0 0.00023 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KND91176.1 - 0.005 16.1 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_12 PF08242.7 KND91176.1 - 0.11 13.0 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF3176 PF11374.3 KND91177.1 - 1.2e-08 34.7 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4611 PF15387.1 KND91177.1 - 0.26 11.4 2.1 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 KND91177.1 - 0.68 10.2 5.8 0.4 11.0 1.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_18 PF00704.23 KND91178.1 - 2.2e-47 162.1 0.1 3.9e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 KND91178.1 - 3.5e-29 100.5 1.1 1.5e-28 98.4 0.7 2.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 KND91178.1 - 3.9e-08 33.0 0.1 0.0043 16.8 0.0 3.1 3 0 0 3 3 3 2 LysM domain SporV_AA PF12164.3 KND91178.1 - 0.15 12.0 0.1 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AA DUF1776 PF08643.5 KND91179.1 - 1.2e-103 346.4 0.0 1.4e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF3328 PF11807.3 KND91180.1 - 6.3e-49 166.5 2.4 8e-49 166.2 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zf-RING_2 PF13639.1 KND91181.1 - 5.2e-13 48.5 6.8 8.4e-13 47.9 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KND91181.1 - 5.9e-08 32.2 3.8 1e-07 31.4 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND91181.1 - 3.2e-07 30.3 4.2 7e-07 29.2 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KND91181.1 - 1.1e-05 25.0 3.9 1.7e-05 24.4 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND91181.1 - 2.7e-05 24.0 5.6 4.5e-05 23.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND91181.1 - 8.2e-05 22.1 2.6 0.00012 21.6 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND91181.1 - 0.0042 16.8 5.2 0.014 15.2 3.6 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KND91181.1 - 0.0093 15.5 6.3 0.016 14.7 4.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Neur_chan_memb PF02932.11 KND91181.1 - 0.011 15.6 0.3 0.08 12.8 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PHD PF00628.24 KND91181.1 - 0.16 11.6 5.8 0.29 10.8 4.0 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 KND91181.1 - 0.23 11.4 2.8 0.66 9.9 1.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4010 PF13194.1 KND91181.1 - 0.33 10.2 1.0 9.6 5.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) zf-C3HC4_4 PF15227.1 KND91181.1 - 0.51 10.2 4.7 1.1 9.2 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING OAD_gamma PF04277.8 KND91181.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.5 3 2 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain RINGv PF12906.2 KND91181.1 - 1.9 8.5 5.5 3.8 7.6 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 KND91181.1 - 4.7 7.0 9.0 4.6 7.0 4.2 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TpcC PF12642.2 KND91182.1 - 0.00078 19.0 1.4 0.0014 18.1 1.0 1.4 1 0 0 1 1 1 1 Conjugative transposon protein TcpC DUF3328 PF11807.3 KND91184.1 - 1.1e-39 136.3 1.6 1.4e-39 136.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.22 KND91185.1 - 1.6e-44 151.5 0.0 5.4e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND91185.1 - 1e-29 103.8 25.6 1.7e-21 76.8 8.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KND91185.1 - 1.6e-09 38.1 1.1 0.17 11.7 0.0 4.3 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KND91185.1 - 2.3e-09 37.5 0.0 0.0001 22.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KND91185.1 - 3.2e-08 33.0 1.2 0.0067 15.6 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KND91185.1 - 2.7e-06 27.5 0.0 0.15 12.2 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KND91185.1 - 3.1e-06 28.0 0.1 0.053 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND91185.1 - 5.4e-06 25.9 0.9 0.091 12.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND91185.1 - 7.1e-06 25.4 0.1 0.17 11.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 KND91185.1 - 5.6e-05 23.0 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KND91185.1 - 9.2e-05 22.6 0.3 1.1 9.4 0.1 3.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KND91185.1 - 0.00013 21.6 0.8 0.21 11.2 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KND91185.1 - 0.00019 21.7 0.1 0.12 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KND91185.1 - 0.00043 19.8 0.8 0.3 10.4 0.2 2.3 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 KND91185.1 - 0.00049 20.5 0.5 0.052 14.0 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 KND91185.1 - 0.00072 19.8 0.9 0.4 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KND91185.1 - 0.00083 18.5 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 KND91185.1 - 0.0049 15.8 0.1 0.12 11.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KND91185.1 - 0.0054 16.6 0.6 1.9 8.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND91185.1 - 0.0086 15.6 0.4 1.1 8.7 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KND91185.1 - 0.01 14.9 0.1 3.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KND91185.1 - 0.02 14.3 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 KND91185.1 - 0.03 12.9 0.0 0.27 9.7 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 KND91185.1 - 0.04 13.4 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KND91185.1 - 0.04 13.5 0.0 0.99 9.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 KND91185.1 - 0.046 13.5 1.6 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.1 KND91185.1 - 0.11 12.4 0.0 7.8 6.4 0.0 3.0 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 KND91185.1 - 0.11 12.1 0.1 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Polyoma_lg_T_C PF06431.6 KND91185.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus GTP_EFTU PF00009.22 KND91185.1 - 0.12 11.7 0.0 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KND91185.1 - 0.13 12.1 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KND91185.1 - 0.15 12.2 0.1 15 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase RecA PF00154.16 KND91185.1 - 0.2 10.6 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PRK PF00485.13 KND91185.1 - 0.21 11.1 0.2 0.43 10.1 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TrwB_AAD_bind PF10412.4 KND91185.1 - 0.27 9.7 1.0 23 3.4 0.0 3.3 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.13 KND91185.1 - 0.33 9.9 0.1 5.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.7 KND91185.1 - 0.45 9.7 0.1 1.4 8.1 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2201_N PF13203.1 KND91186.1 - 3 6.9 11.9 3.6 6.6 8.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Apt1 PF10351.4 KND91186.1 - 9.6 4.9 10.4 11 4.7 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1708 PF08101.6 KND91187.1 - 1.1e-148 495.5 0.0 1.5e-148 495.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RNA_pol_Rpb1_1 PF04997.7 KND91188.1 - 1.8e-110 369.3 0.0 2.9e-110 368.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KND91188.1 - 1.2e-100 336.3 0.0 3.1e-100 334.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KND91188.1 - 2.8e-70 235.5 0.0 6.3e-70 234.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KND91188.1 - 2.6e-54 183.8 0.0 4.7e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KND91188.1 - 4.2e-44 150.0 0.0 9e-44 148.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KND91188.1 - 7.5e-43 145.4 8.4 4.7e-42 142.9 6.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KND91188.1 - 5.5e-37 125.8 0.2 1.3e-36 124.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-CCCH PF00642.19 KND91191.1 - 2.4e-15 55.7 34.3 1.1e-07 31.2 0.4 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_23 PF13489.1 KND91191.1 - 1e-07 31.7 0.0 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain zf-CCCH_2 PF14608.1 KND91191.1 - 0.014 15.4 18.7 0.088 12.8 0.0 4.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Methyltransf_12 PF08242.7 KND91191.1 - 0.081 13.4 0.1 0.44 11.0 0.0 2.3 3 1 0 3 3 3 0 Methyltransferase domain bZIP_Maf PF03131.12 KND91192.1 - 0.044 14.0 1.4 0.18 12.0 1.0 2.1 1 0 0 1 1 1 0 bZIP Maf transcription factor Memo PF01875.12 KND91193.1 - 4.4e-70 235.7 0.0 5.1e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein SET PF00856.23 KND91194.1 - 6.1e-09 36.3 0.0 1.9e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 SET domain Tom37_C PF11801.3 KND91195.1 - 1e-21 77.5 0.0 1.9e-21 76.6 0.0 1.4 1 1 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KND91195.1 - 9e-21 73.9 4.3 1e-20 73.7 0.1 2.8 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein DUF3652 PF12372.3 KND91195.1 - 0.013 15.0 0.1 0.033 13.7 0.1 1.7 1 0 0 1 1 1 0 Huntingtin protein region DUF434 PF04256.7 KND91196.1 - 0.047 13.0 0.2 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF434) tRNA-synt_1 PF00133.17 KND91197.1 - 9.2e-153 509.4 0.0 1.3e-152 508.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KND91197.1 - 3.2e-22 78.7 0.0 1.4e-12 46.9 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KND91197.1 - 1.7e-15 57.0 0.0 3.1e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KND91197.1 - 3.9e-05 23.1 4.0 8.7e-05 22.0 2.8 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 KND91197.1 - 0.0082 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 DUF945 PF06097.6 KND91197.1 - 0.053 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) tRNA-synt_1b PF00579.20 KND91197.1 - 0.19 10.8 0.1 0.53 9.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Pescadillo_N PF06732.6 KND91198.1 - 7e-113 376.5 0.3 1.5e-112 375.4 0.2 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 KND91198.1 - 8.2e-11 41.8 0.0 2.9e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CENP-T PF15511.1 KND91198.1 - 0.21 10.8 20.1 0.39 9.9 13.9 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 KND91198.1 - 5.6 5.3 22.0 9.6 4.5 15.2 1.3 1 0 0 1 1 1 0 Daxx Family PIG-U PF06728.8 KND91199.1 - 2e-122 408.7 24.0 2.3e-122 408.5 16.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U zf-C2H2 PF00096.21 KND91200.1 - 0.0021 18.2 0.5 0.0041 17.3 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND91200.1 - 0.019 15.2 0.4 0.038 14.3 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger RRN9 PF10680.4 KND91201.1 - 4.8e-14 51.8 0.2 1.2e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor MFS_1 PF07690.11 KND91202.1 - 2.3e-49 168.0 61.3 2.2e-47 161.4 42.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND91202.1 - 4.7e-24 84.5 20.6 6.2e-24 84.1 13.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KND91202.1 - 1.9e-15 56.3 6.6 1.9e-15 56.3 4.6 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter Kinesin PF00225.18 KND91203.1 - 4e-110 367.6 2.2 4e-110 367.6 1.6 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KND91203.1 - 8.1e-09 35.7 1.9 8.1e-09 35.7 1.3 4.2 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding DUF2570 PF10828.3 KND91203.1 - 9.3 5.8 24.7 2.1 7.9 0.3 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2570) GrpB PF04229.9 KND91205.1 - 2.3e-31 108.7 0.0 2.8e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Sulfatase PF00884.18 KND91206.1 - 2.9e-58 197.4 0.0 3.7e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KND91206.1 - 1e-20 73.3 0.3 1e-20 73.3 0.2 2.2 2 1 1 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KND91206.1 - 5.5e-11 42.3 0.4 2.6e-09 36.8 0.2 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KND91206.1 - 3.4e-05 22.4 0.0 4.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KND91206.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 KND91206.1 - 0.088 12.1 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Metalloenzyme superfamily TPT PF03151.11 KND91207.1 - 2.4e-23 82.4 7.9 2.4e-23 82.4 5.4 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KND91207.1 - 1.4e-06 27.4 19.9 4e-06 25.9 13.8 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KND91207.1 - 0.042 13.8 33.1 0.46 10.5 6.1 3.2 2 2 0 2 2 2 0 EamA-like transporter family Mito_fiss_reg PF05308.6 KND91208.1 - 5.8 6.2 15.8 13 5.0 10.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator PCI PF01399.22 KND91209.1 - 4e-09 36.7 0.0 9.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 KND91210.1 - 3e-10 40.2 0.0 6.4e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Ribosomal_L31e PF01198.14 KND91211.1 - 2.1e-37 126.6 0.9 2.6e-37 126.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 KND91212.1 - 1.5e-48 163.8 0.0 1.9e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KND91212.1 - 0.0019 18.0 0.0 0.0027 17.5 0.0 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KND91212.1 - 0.0087 15.7 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain Aldo_ket_red PF00248.16 KND91213.1 - 1.4e-38 132.3 0.1 2e-36 125.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Na_Ca_ex PF01699.19 KND91214.1 - 1.5e-35 121.8 36.9 6.1e-21 74.4 11.2 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pkinase PF00069.20 KND91215.1 - 2.1e-61 207.3 0.0 3.9e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91215.1 - 5.4e-34 117.4 0.0 8.3e-29 100.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KND91215.1 - 2e-05 23.7 0.1 0.02 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KND91215.1 - 0.00034 20.4 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND91215.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND91215.1 - 0.21 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CLTH PF10607.4 KND91216.1 - 2.5e-14 53.1 0.1 6.5e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Ded_cyto PF06920.8 KND91216.1 - 0.038 13.3 0.6 0.066 12.5 0.1 1.6 2 0 0 2 2 2 0 Dedicator of cytokinesis DUF848 PF05852.6 KND91216.1 - 0.12 12.1 5.1 0.065 13.0 1.3 2.0 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin PF00804.20 KND91216.1 - 0.18 11.9 4.2 4 7.6 1.0 2.3 2 0 0 2 2 2 0 Syntaxin zf-RING_UBOX PF13445.1 KND91217.1 - 1.7e-19 69.2 2.0 3e-19 68.4 1.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 KND91217.1 - 8.5e-10 38.4 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 KND91217.1 - 9.8e-07 28.5 2.4 1.5e-06 27.8 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND91217.1 - 1.9e-06 27.7 3.0 3.2e-06 27.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND91217.1 - 2.3e-06 27.1 1.8 3.8e-06 26.4 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KND91217.1 - 3.9e-06 26.2 0.1 4.5e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 KND91217.1 - 5.5e-06 25.9 2.1 9e-06 25.3 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND91217.1 - 2.6e-05 23.7 3.1 4.9e-05 22.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 KND91217.1 - 0.00073 18.9 2.1 0.0016 17.8 1.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 KND91217.1 - 0.0015 18.0 2.2 0.0025 17.3 1.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KND91217.1 - 0.0029 17.4 2.3 0.0057 16.4 1.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KND91217.1 - 0.012 15.1 3.7 0.027 14.0 2.6 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Pellino PF04710.9 KND91217.1 - 0.021 13.4 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 Pellino LmjF365940-deam PF14421.1 KND91217.1 - 0.026 13.8 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Amidase PF01425.16 KND91218.1 - 2.8e-56 191.2 0.1 3.9e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Amidase GATA PF00320.22 KND91220.1 - 5.5e-16 57.6 4.9 9.6e-16 56.8 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 KND91220.1 - 7e-12 45.2 0.0 2.6e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KND91220.1 - 7e-09 35.9 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KND91220.1 - 1.4e-06 28.0 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 KND91220.1 - 8.6e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 KND91220.1 - 1.1e-05 25.3 0.1 3.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold TF_Zn_Ribbon PF08271.7 KND91220.1 - 0.13 11.6 0.8 0.76 9.1 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding RRN7 PF11781.3 KND91220.1 - 0.88 9.1 2.9 15 5.2 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF4428 PF14471.1 KND91220.1 - 2.5 7.9 5.7 0.44 10.3 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) AAA_23 PF13476.1 KND91221.1 - 1.3e-27 97.4 0.1 1.3e-27 97.4 0.1 7.2 1 1 2 4 4 1 1 AAA domain AAA_13 PF13166.1 KND91221.1 - 4.1e-12 45.3 98.4 1.8e-05 23.4 10.7 5.9 3 3 1 5 5 5 4 AAA domain SbcCD_C PF13558.1 KND91221.1 - 8.6e-11 41.6 2.3 1.2e-10 41.1 0.0 2.6 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KND91221.1 - 7.4e-10 39.2 5.8 4.3e-05 23.6 1.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KND91221.1 - 5.8e-06 25.6 0.0 5.8e-06 25.6 0.0 5.1 3 1 0 4 4 3 2 AAA ATPase domain DUF3584 PF12128.3 KND91221.1 - 0.00026 18.5 22.3 0.00026 18.5 15.4 5.5 3 1 2 5 5 5 1 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.3 KND91221.1 - 0.00039 20.1 7.0 0.00039 20.1 4.8 9.3 6 3 2 8 8 7 2 TATA element modulatory factor 1 TATA binding Cluap1 PF10234.4 KND91221.1 - 0.0026 17.0 14.3 0.0026 17.0 9.9 6.6 2 2 1 5 5 3 1 Clusterin-associated protein-1 AAA_29 PF13555.1 KND91221.1 - 0.0029 17.1 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF948 PF06103.6 KND91221.1 - 0.008 16.0 31.3 0.015 15.1 0.3 7.6 6 2 3 9 9 9 3 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 KND91221.1 - 0.016 15.0 1.1 0.016 15.0 0.8 8.3 5 4 3 8 8 8 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.22 KND91221.1 - 0.061 13.6 0.0 0.061 13.6 0.0 6.8 5 1 0 5 5 4 0 ABC transporter AAA_19 PF13245.1 KND91221.1 - 0.085 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KND91221.1 - 0.16 11.9 0.0 0.16 11.9 0.0 4.7 2 2 1 5 5 5 0 AAA ATPase domain SMC_N PF02463.14 KND91221.1 - 1.8 7.7 63.8 40 3.3 44.2 3.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NPV_P10 PF05531.7 KND91221.1 - 2 8.7 35.5 0.067 13.4 0.3 7.8 6 3 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KND91221.1 - 3.3 6.8 31.9 0.57 9.3 0.4 5.6 4 2 1 6 6 6 0 Reovirus sigma C capsid protein PPP4R2 PF09184.6 KND91222.1 - 3.7e-10 39.8 14.7 4e-10 39.7 0.0 2.5 3 0 0 3 3 3 1 PPP4R2 Herpes_UL46 PF03387.9 KND91222.1 - 0.19 9.9 0.0 0.31 9.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL46 protein Ribosomal_L36 PF00444.13 KND91224.1 - 1.4e-21 76.1 11.6 2.1e-21 75.6 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Complex1_LYR_1 PF13232.1 KND91225.1 - 4.1e-16 58.9 0.3 6.5e-16 58.2 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KND91225.1 - 1.4e-15 56.7 0.4 2.4e-15 56.0 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KND91225.1 - 0.057 13.8 0.1 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like MMS22L_C PF14911.1 KND91225.1 - 0.14 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal ABC_tran PF00005.22 KND91227.1 - 1.1e-50 171.4 0.0 1.1e-29 103.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND91227.1 - 7.8e-31 107.4 20.4 5.4e-20 71.9 7.9 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KND91227.1 - 4e-09 36.0 0.2 0.00015 21.0 0.0 4.0 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KND91227.1 - 2.7e-05 23.6 0.1 0.0069 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND91227.1 - 4.3e-05 23.5 0.1 0.43 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KND91227.1 - 0.00042 19.7 0.8 0.89 9.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KND91227.1 - 0.00047 20.2 0.6 2.8 7.8 0.0 3.7 3 1 0 3 3 2 1 AAA domain T2SE PF00437.15 KND91227.1 - 0.00088 18.2 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 KND91227.1 - 0.00094 18.3 0.2 0.48 9.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KND91227.1 - 0.0019 18.1 0.5 0.34 10.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KND91227.1 - 0.0034 17.5 0.1 7 6.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KND91227.1 - 0.0059 17.0 0.7 5.1 7.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein IstB_IS21 PF01695.12 KND91227.1 - 0.025 13.9 0.1 17 4.7 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein ArgK PF03308.11 KND91227.1 - 0.045 12.5 0.1 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_23 PF13476.1 KND91227.1 - 0.049 13.9 5.1 0.1 12.8 0.2 2.6 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 KND91227.1 - 0.05 13.4 4.3 0.58 9.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 KND91227.1 - 0.053 12.4 0.4 0.51 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.1 KND91227.1 - 0.056 13.3 0.0 7.6 6.5 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KND91227.1 - 0.08 12.3 0.6 6.4 6.1 0.1 2.7 2 1 0 3 3 3 0 AAA-like domain WD40 PF00400.27 KND91228.1 - 2.7e-25 87.2 15.6 1.6e-07 30.9 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KND91228.1 - 0.00019 21.1 0.1 0.073 12.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A LigD_N PF13298.1 KND91229.1 - 2.3e-24 85.4 0.0 5.4e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Peroxin-13_N PF04088.8 KND91230.1 - 3e-55 186.5 0.0 4.6e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KND91230.1 - 1.2e-09 37.4 0.0 2.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND91230.1 - 1.8e-06 27.2 0.0 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND91230.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Atg14 PF10186.4 KND91231.1 - 3.3e-74 249.5 0.0 3.9e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 XRCC4 PF06632.7 KND91231.1 - 0.14 10.9 1.6 0.23 10.2 1.1 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 FUSC PF04632.7 KND91231.1 - 4.5 5.5 12.8 6.3 5.1 8.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.20 KND91232.1 - 5e-55 186.4 0.0 6.2e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91232.1 - 2.3e-15 56.3 0.0 4.1e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND91232.1 - 2.3e-06 27.5 0.1 0.00022 21.0 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KND91232.1 - 0.021 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ING PF12998.2 KND91233.1 - 0.15 12.3 1.7 0.27 11.5 1.2 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RR_TM4-6 PF06459.7 KND91233.1 - 0.3 10.9 3.7 0.46 10.3 2.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Scm3 PF10384.4 KND91234.1 - 1.7e-18 65.8 0.0 3.6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.7 KND91235.1 - 2.2e-125 417.8 0.0 2.8e-125 417.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 AAA_13 PF13166.1 KND91235.1 - 0.00062 18.3 5.5 0.00083 17.9 3.8 1.1 1 0 0 1 1 1 1 AAA domain TMF_TATA_bd PF12325.3 KND91235.1 - 0.00095 18.8 10.2 0.0011 18.7 5.5 2.0 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 KND91235.1 - 0.0055 16.9 5.1 0.0055 16.9 3.6 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF904) DUF972 PF06156.8 KND91235.1 - 0.029 14.7 4.3 0.03 14.6 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CCDC155 PF14662.1 KND91235.1 - 0.043 13.4 9.5 0.069 12.7 6.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 V_ATPase_I PF01496.14 KND91235.1 - 0.059 11.2 5.7 0.08 10.7 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KND91235.1 - 0.076 11.4 3.3 0.11 10.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Suppressor_APC PF11414.3 KND91235.1 - 0.25 11.1 8.9 9.5 6.0 3.7 2.6 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF3450 PF11932.3 KND91235.1 - 0.66 9.2 10.0 1.2 8.3 6.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 KND91235.1 - 0.69 9.4 11.6 1.2 8.6 8.1 1.3 1 0 0 1 1 1 0 IncA protein zf-C4H2 PF10146.4 KND91235.1 - 1.4 8.9 11.8 0.039 13.9 3.6 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein Seryl_tRNA_N PF02403.17 KND91235.1 - 1.6 8.7 11.6 3.2 7.8 8.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KND91235.1 - 1.9 8.9 9.3 2.8 8.4 5.3 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 KND91235.1 - 2.8 7.8 19.8 4.3 7.2 10.5 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Dus PF01207.12 KND91236.1 - 3.4e-37 127.9 0.0 1.1e-27 96.7 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KND91236.1 - 0.0055 16.3 7.8 0.3 10.8 0.5 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HIG_1_N PF04588.8 KND91237.1 - 7.3e-08 32.0 1.5 1.6e-07 30.9 1.0 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Bud13 PF09736.4 KND91237.1 - 0.025 14.8 0.1 0.025 14.8 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.7 KND91238.1 - 0.071 11.4 50.9 0.88 7.8 35.2 3.0 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAPPC-Trs85 PF12739.2 KND91239.1 - 4.1e-113 378.1 1.3 1.1e-112 376.7 0.7 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit adh_short_C2 PF13561.1 KND91240.1 - 9.5e-28 97.5 0.0 1.1e-27 97.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND91240.1 - 1.6e-27 96.4 0.7 2.1e-27 96.0 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND91240.1 - 1.1e-13 51.2 0.4 1.8e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND91240.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND91240.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aa_trans PF01490.13 KND91243.1 - 6.7e-78 261.9 23.8 7.9e-78 261.7 16.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trigger_C PF05698.9 KND91244.1 - 0.0046 16.8 0.6 0.017 14.9 0.1 2.0 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus Cullin_Nedd8 PF10557.4 KND91244.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Cullin protein neddylation domain Caudal_act PF04731.7 KND91244.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.0 2 1 0 2 2 2 0 Caudal like protein activation region ABC2_membrane PF01061.19 KND91245.1 - 2.4e-35 121.5 20.8 2.4e-35 121.5 14.4 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KND91245.1 - 5.7e-25 88.2 0.0 1.1e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND91245.1 - 1.1e-09 38.6 0.0 1.7e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND91245.1 - 3.8e-05 23.1 0.0 0.0072 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 KND91245.1 - 0.00018 21.3 21.8 0.016 15.2 2.4 4.5 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_15 PF13175.1 KND91245.1 - 0.0018 17.4 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KND91245.1 - 0.0029 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KND91245.1 - 0.0035 16.4 25.9 0.0035 16.4 18.0 2.4 2 1 1 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 KND91245.1 - 0.0037 16.4 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KND91245.1 - 0.039 13.1 0.0 0.54 9.4 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KND91245.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KND91245.1 - 0.048 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3827 PF12877.2 KND91245.1 - 0.058 11.4 0.1 0.085 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NACHT PF05729.7 KND91245.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 KND91245.1 - 0.091 13.5 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KND91245.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KND91245.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KND91245.1 - 0.14 12.4 0.2 0.25 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KND91245.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KND91245.1 - 0.22 11.1 0.1 0.45 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 But2 PF09792.4 KND91246.1 - 2.6e-52 176.4 0.6 3e-52 176.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain EF-hand_5 PF13202.1 KND91246.1 - 0.14 11.5 0.2 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 EF hand NGP1NT PF08153.7 KND91247.1 - 9.2e-48 161.4 0.3 1.4e-47 160.9 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KND91247.1 - 6.7e-16 58.2 0.1 1.6e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KND91247.1 - 0.00016 21.5 0.5 0.15 11.8 0.1 3.3 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 KND91247.1 - 0.0036 16.5 0.0 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KND91247.1 - 0.0045 16.4 0.1 0.32 10.3 0.0 2.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KND91247.1 - 0.034 13.3 0.1 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 KND91247.1 - 0.035 13.3 0.0 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KND91247.1 - 0.055 13.9 0.2 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Arginase PF00491.16 KND91248.1 - 1.3e-77 260.8 0.2 1.3e-77 260.8 0.2 1.4 2 0 0 2 2 2 1 Arginase family WD40 PF00400.27 KND91249.1 - 4.9e-38 127.6 5.8 3.2e-08 33.1 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KND91249.1 - 0.063 12.9 1.2 1.4 8.5 0.1 2.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Raffinose_syn PF05691.7 KND91250.1 - 5.4e-56 189.5 4.3 1.7e-53 181.2 3.0 2.2 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KND91250.1 - 6.7e-05 21.7 1.6 0.00012 20.9 1.1 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 KND91250.1 - 0.0003 19.7 0.8 0.00047 19.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ocr PF08684.5 KND91250.1 - 0.0062 16.5 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 DNA mimic ocr IMPDH PF00478.20 KND91251.1 - 1.5e-130 435.2 1.0 1.9e-130 434.8 0.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KND91251.1 - 3.5e-14 52.2 0.0 2.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KND91251.1 - 6.5e-07 28.8 3.2 0.027 13.6 2.5 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KND91251.1 - 1.4e-06 27.4 2.0 1.5e-05 24.0 0.4 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.9 KND91251.1 - 0.0011 18.1 0.6 0.13 11.2 0.2 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KND91251.1 - 0.0014 17.9 1.0 0.012 14.9 0.7 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein Acetyltransf_1 PF00583.19 KND91252.1 - 5.8e-13 48.6 0.0 9.4e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND91252.1 - 1.4e-07 31.6 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND91252.1 - 1.9e-07 31.2 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND91252.1 - 1.6e-06 27.7 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KND91252.1 - 1.8e-05 24.6 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND91252.1 - 0.00066 19.8 0.0 0.00095 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2156 PF09924.4 KND91252.1 - 0.031 13.1 0.0 0.051 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) Acetyltransf_CG PF14542.1 KND91252.1 - 0.056 13.3 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Histidinol_dh PF00815.15 KND91253.1 - 2.9e-180 599.3 6.2 3.9e-180 598.8 4.3 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KND91253.1 - 1.6e-25 88.5 0.1 3.2e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KND91253.1 - 1.2e-10 41.4 0.1 3.6e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 KND91254.1 - 3.9e-28 97.8 0.0 3.3e-27 94.8 0.0 2.0 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_M16 PF00675.15 KND91255.1 - 1.7e-58 196.5 0.3 3.8e-58 195.4 0.2 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KND91255.1 - 2.8e-38 131.4 0.0 5.7e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Pyr_redox_2 PF07992.9 KND91256.1 - 3.8e-28 98.7 0.3 5.6e-28 98.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND91256.1 - 6.2e-17 61.7 0.6 7.2e-15 55.1 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND91256.1 - 9e-12 45.4 0.1 1.4e-06 28.5 0.0 3.1 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND91256.1 - 4.2e-07 29.1 3.5 0.044 12.6 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KND91256.1 - 1.5e-05 25.1 0.1 0.0023 18.1 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 KND91256.1 - 0.00027 20.1 0.1 0.066 12.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KND91256.1 - 0.00028 19.9 0.3 0.71 8.7 0.0 3.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KND91256.1 - 0.00031 20.7 1.9 0.047 13.7 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND91256.1 - 0.00056 19.0 0.3 0.0022 17.1 0.0 2.1 2 1 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 KND91256.1 - 0.0014 18.7 0.2 1.6 8.8 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KND91256.1 - 0.0023 16.8 1.6 1.1 8.0 0.0 3.9 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KND91256.1 - 0.043 12.6 4.2 0.57 8.9 0.1 3.0 1 1 1 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KND91256.1 - 0.056 12.4 1.4 20 4.0 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain Vps53_N PF04100.7 KND91257.1 - 5.1e-104 348.0 1.7 8.4e-104 347.3 1.2 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KND91257.1 - 1.5e-07 30.6 8.4 2.7e-07 29.8 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KND91257.1 - 0.0011 17.1 6.9 0.0011 17.1 4.8 1.8 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Spc7 PF08317.6 KND91257.1 - 0.003 16.2 6.7 0.003 16.2 4.6 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 KND91257.1 - 0.013 15.4 4.8 0.014 15.4 0.5 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 KND91257.1 - 9.7 6.0 8.3 39 4.1 3.2 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CR6_interact PF10147.4 KND91258.1 - 0.001 18.4 0.3 0.002 17.5 0.2 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1183 PF06682.7 KND91258.1 - 0.002 17.7 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 KND91258.1 - 0.012 15.3 2.3 0.028 14.0 1.6 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SURF2 PF05477.6 KND91258.1 - 0.019 14.1 0.2 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) TMEM154 PF15102.1 KND91258.1 - 0.039 13.6 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.11 KND91258.1 - 0.062 11.5 0.0 0.091 11.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KND91258.1 - 0.07 13.5 0.1 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KND91258.1 - 0.22 11.0 0.3 0.38 10.3 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RCR PF12273.3 KND91258.1 - 5.5 7.5 6.8 2.7 8.5 1.7 2.5 2 1 1 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF2217 PF10265.4 KND91258.1 - 5.5 5.6 10.1 4.8 5.8 5.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2217) FMN_red PF03358.10 KND91260.1 - 2.8e-06 26.9 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KND91260.1 - 5.7e-06 25.9 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 KND91260.1 - 7.8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin Tyrosinase PF00264.15 KND91261.1 - 3.6e-34 118.8 1.2 4.9e-34 118.4 0.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Saccharop_dh PF03435.13 KND91262.1 - 3.8e-97 325.6 0.0 4.9e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pro_isomerase PF00160.16 KND91262.1 - 1.5e-41 142.2 0.1 2.3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Shikimate_DH PF01488.15 KND91262.1 - 0.0001 22.4 0.1 0.00038 20.5 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TEA PF01285.13 KND91263.1 - 2.1e-15 56.8 4.1 1.1e-12 47.8 0.0 2.6 3 0 0 3 3 3 2 TEA/ATTS domain family RRM_1 PF00076.17 KND91264.1 - 2.1e-75 248.3 0.6 2.8e-20 71.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND91264.1 - 4.4e-60 199.5 0.2 1.5e-15 56.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND91264.1 - 2.2e-31 107.4 0.0 2.5e-08 33.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KND91264.1 - 3.4e-06 26.8 0.1 0.42 10.4 0.0 4.8 5 0 0 5 5 5 2 RNA binding motif Limkain-b1 PF11608.3 KND91264.1 - 3.4e-06 26.7 0.1 4.5 7.1 0.0 5.7 6 1 0 6 6 6 2 Limkain b1 Nup35_RRM_2 PF14605.1 KND91264.1 - 0.032 14.0 0.0 18 5.2 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Thg1C PF14413.1 KND91265.1 - 6.2e-54 180.8 0.3 8.2e-54 180.4 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KND91265.1 - 4.3e-46 155.8 0.0 6.3e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 KND91266.1 - 5e-10 38.8 5.6 0.0025 17.6 0.3 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 KND91266.1 - 8.3e-06 25.6 0.2 0.071 12.8 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KND91266.1 - 0.092 12.1 0.2 0.25 10.7 0.2 1.9 1 1 0 1 1 1 0 PQQ-like domain ADH_zinc_N_2 PF13602.1 KND91267.1 - 1.4e-18 68.0 0.1 2.7e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KND91267.1 - 3.1e-16 59.1 0.7 4.9e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND91267.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF726 PF05277.7 KND91268.1 - 4.1e-102 341.6 0.2 5.3e-102 341.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KND91268.1 - 2.6e-06 27.4 0.7 7e-06 26.0 0.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KND91268.1 - 0.00014 22.1 2.2 0.00014 22.1 0.0 2.1 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_5 PF12695.2 KND91268.1 - 0.0009 19.0 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KND91268.1 - 0.0038 16.9 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KND91268.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Sel1 PF08238.7 KND91269.1 - 5.2e-42 141.3 31.6 2.9e-05 24.5 0.0 13.1 14 0 0 14 14 14 10 Sel1 repeat TPR_17 PF13431.1 KND91269.1 - 2.6e-06 27.1 4.6 7.6 7.0 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KND91269.1 - 7.4e-06 26.0 8.0 0.12 12.8 0.4 6.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND91269.1 - 0.00081 18.9 15.0 0.011 15.3 0.0 5.7 5 1 0 5 5 5 1 TPR repeat TPR_7 PF13176.1 KND91269.1 - 0.001 18.7 8.3 4.4 7.3 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND91269.1 - 0.69 10.7 6.6 34 5.4 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND91269.1 - 5.4 7.4 13.2 1.7 9.0 0.5 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat UDG PF03167.14 KND91270.1 - 4.5e-26 91.1 0.5 8.5e-26 90.2 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily PLAC8 PF04749.12 KND91271.1 - 8.5e-23 80.9 9.7 1.2e-22 80.5 6.7 1.2 1 0 0 1 1 1 1 PLAC8 family fn3 PF00041.16 KND91272.1 - 6.7e-10 38.9 0.1 2.2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain F-box-like PF12937.2 KND91274.1 - 3e-12 46.0 1.7 6.4e-12 45.0 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND91274.1 - 8e-11 41.3 2.2 2.2e-10 39.9 1.5 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KND91274.1 - 0.055 13.8 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Rhodanese PF00581.15 KND91275.1 - 4.4e-20 72.1 0.0 1.1e-10 41.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF605 PF04652.11 KND91276.1 - 5.2 6.3 15.1 6.4 6.0 10.5 1.2 1 0 0 1 1 1 0 Vta1 like RCR PF12273.3 KND91278.1 - 0.014 15.9 13.6 0.035 14.6 9.4 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pil1 PF13805.1 KND91279.1 - 4.8e-152 504.7 0.1 5.9e-152 504.4 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KND91279.1 - 0.012 14.9 1.4 0.025 13.9 0.9 1.6 1 1 0 1 1 1 0 FAM92 protein BSP_II PF05432.6 KND91279.1 - 0.073 12.3 8.0 0.11 11.7 5.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 KND91279.1 - 0.42 11.0 4.2 1.3 9.5 2.9 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.7 KND91279.1 - 1.4 8.1 3.6 2.1 7.5 2.5 1.2 1 0 0 1 1 1 0 NOA36 protein SET PF00856.23 KND91280.1 - 1.5e-20 74.1 0.2 1.5e-20 74.1 0.2 3.2 3 1 0 3 3 3 1 SET domain Glyoxalase_2 PF12681.2 KND91282.1 - 2.2e-06 28.1 0.1 8.5e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KND91282.1 - 0.0062 16.5 0.1 0.048 13.6 0.0 2.2 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Suf PF05843.9 KND91283.1 - 1.4e-13 51.1 5.9 0.0079 15.9 0.0 6.2 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_12 PF13424.1 KND91283.1 - 1.5e-10 40.8 1.9 0.92 9.4 0.0 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND91283.1 - 3.8e-07 30.1 20.7 5.1 8.0 0.0 10.4 10 2 1 11 11 11 1 Tetratricopeptide repeat TPR_15 PF13429.1 KND91283.1 - 5.6e-07 28.9 4.7 0.00028 20.0 0.4 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND91283.1 - 3.3e-05 23.4 3.8 0.3 10.7 0.0 6.2 7 0 0 7 7 7 1 TPR repeat Mad3_BUB1_I PF08311.7 KND91283.1 - 0.00021 21.0 8.9 5.4 6.8 0.1 7.1 7 1 1 8 8 8 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.1 KND91283.1 - 0.00045 20.7 13.1 0.29 11.8 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KND91283.1 - 0.0016 17.3 7.0 0.074 11.9 0.0 4.6 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 KND91283.1 - 0.019 14.7 4.5 16 5.5 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND91283.1 - 0.046 13.5 8.6 0.071 12.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat HAT PF02184.11 KND91283.1 - 1.1 9.0 15.4 0.53 10.0 1.0 6.3 6 1 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.12 KND91283.1 - 4.7 7.3 19.4 24 5.1 0.1 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat RRM_1 PF00076.17 KND91285.1 - 2e-23 81.7 0.3 1.4e-10 40.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND91285.1 - 1.3e-16 60.3 0.1 3.1e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND91285.1 - 1.9e-16 59.6 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUI1 PF01253.17 KND91285.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor SUI1 ATP-synt_D PF01813.12 KND91286.1 - 2e-63 213.4 0.9 2e-63 213.4 0.6 1.3 2 0 0 2 2 2 1 ATP synthase subunit D ARGLU PF15346.1 KND91286.1 - 5.8 6.6 9.3 4.8 6.9 0.1 2.5 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 HSP70 PF00012.15 KND91289.1 - 1.1e-229 763.4 6.2 1.2e-229 763.2 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND91289.1 - 1e-15 57.1 0.4 8.3e-15 54.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KND91289.1 - 0.0023 17.6 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KND91289.1 - 0.021 14.6 2.4 4 7.2 0.7 3.6 2 1 0 2 2 2 0 Cell division protein FtsA MFS_1 PF07690.11 KND91291.1 - 1.4e-33 116.0 36.2 1.9e-26 92.6 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KND91291.1 - 8.2e-07 27.6 0.2 1.6e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RPEL PF02755.10 KND91292.1 - 7.3e-18 63.3 2.6 2e-08 33.2 0.2 2.3 2 0 0 2 2 2 2 RPEL repeat AT_hook PF02178.14 KND91293.1 - 0.09 12.4 1.4 0.19 11.5 1.0 1.6 1 0 0 1 1 1 0 AT hook motif BRCT PF00533.21 KND91294.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Aldose_epim PF01263.15 KND91296.1 - 1.3e-41 142.7 0.0 1.4e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.11 KND91297.1 - 1.7e-189 629.7 0.0 2e-189 629.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Myosin_head PF00063.16 KND91298.1 - 1.1e-232 774.0 2.1 1.7e-232 773.3 1.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KND91298.1 - 6.7e-40 136.5 0.0 2.1e-39 134.9 0.0 1.9 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KND91298.1 - 8.5e-12 44.2 0.1 1.6e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND91298.1 - 9.4e-11 41.1 0.1 2.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND91298.1 - 5.1e-08 32.2 0.0 1.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KND91298.1 - 0.0026 17.2 10.0 0.039 13.5 1.6 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 KND91298.1 - 0.007 15.6 0.6 2.2 7.5 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 KND91298.1 - 0.0071 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND91298.1 - 0.022 13.8 0.0 0.069 12.2 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin DUF552 PF04472.7 KND91298.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) NACHT PF05729.7 KND91298.1 - 0.055 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KND91298.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KND91298.1 - 0.093 13.5 0.0 0.28 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Peptidase_C14 PF00656.17 KND91299.1 - 0.0051 16.5 0.6 1.5 8.4 0.0 2.7 2 1 1 3 3 3 2 Caspase domain SelP_N PF04592.9 KND91299.1 - 1.3 8.3 4.1 2.8 7.2 2.9 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_transf_90 PF05686.7 KND91300.1 - 0.00038 19.2 0.3 0.011 14.4 0.2 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 90 Amidase PF01425.16 KND91301.1 - 1.4e-88 297.6 0.0 2.3e-88 296.9 0.0 1.3 1 0 0 1 1 1 1 Amidase WLM PF08325.5 KND91302.1 - 5.6e-34 117.6 0.4 9.6e-34 116.8 0.3 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KND91302.1 - 3.1e-05 22.9 2.7 5.4e-05 22.2 1.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KND91302.1 - 0.0015 18.3 3.2 0.0015 18.3 2.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 DUF3069 PF11269.3 KND91302.1 - 0.12 12.4 0.1 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) SprT-like PF10263.4 KND91302.1 - 0.59 9.7 3.3 0.23 11.0 0.4 1.7 2 0 0 2 2 2 0 SprT-like family DUF955 PF06114.8 KND91302.1 - 3.9 7.2 5.6 0.96 9.1 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF955) WLM PF08325.5 KND91303.1 - 3.6e-50 170.4 0.0 5.9e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KND91303.1 - 3.5e-05 22.8 2.7 6.3e-05 21.9 1.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KND91303.1 - 0.0017 18.1 3.2 0.0017 18.1 2.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 KND91303.1 - 0.17 11.5 0.1 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 SprT-like family DUF1713 PF08213.6 KND91304.1 - 2e-10 40.0 21.5 2e-10 40.0 14.9 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KND91304.1 - 0.0021 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial protein Pet20 GNAT_acetyltr_2 PF13718.1 KND91305.1 - 1.7e-79 265.6 0.0 3e-79 264.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KND91305.1 - 2.6e-65 219.3 0.1 1.5e-64 216.8 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KND91305.1 - 5.6e-39 131.7 0.1 1.4e-38 130.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KND91305.1 - 1e-35 121.8 0.5 3.2e-35 120.2 0.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KND91305.1 - 0.0072 16.4 0.0 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Dak2 PF02734.12 KND91306.1 - 9.1e-31 106.8 0.1 1e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 DAK2 domain DHDPS PF00701.17 KND91307.1 - 3.2e-43 147.3 0.0 3.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HATPase_c PF02518.21 KND91308.1 - 1.2e-29 102.2 0.2 2.5e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KND91308.1 - 3.6e-23 81.3 0.1 1.4e-22 79.4 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KND91308.1 - 3.6e-22 78.6 0.0 1.6e-13 50.9 0.0 4.1 4 0 0 4 4 4 3 PAS domain Response_reg PF00072.19 KND91308.1 - 1.9e-18 66.4 0.0 5.1e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KND91308.1 - 6.2e-15 55.0 0.2 1.1e-13 51.0 0.2 2.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KND91308.1 - 3.7e-10 39.5 0.1 0.00096 18.9 0.0 4.3 5 0 0 5 5 5 2 PAS fold PAS_4 PF08448.5 KND91308.1 - 6.5e-10 39.0 2.8 3.4e-05 23.8 0.0 5.0 4 2 0 4 4 4 2 PAS fold PAS_8 PF13188.1 KND91308.1 - 2.6e-06 27.0 0.0 0.045 13.6 0.0 4.4 4 0 0 4 4 4 2 PAS domain HATPase_c_3 PF13589.1 KND91308.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_8 PF08022.7 KND91309.1 - 1.5e-22 79.4 0.0 3.3e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KND91309.1 - 4.7e-22 78.5 0.0 7.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KND91309.1 - 1.6e-18 67.0 9.5 1.6e-18 67.0 6.6 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KND91309.1 - 9.7e-05 22.4 0.0 0.00027 21.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF1405 PF07187.6 KND91310.1 - 0.065 12.9 3.2 0.11 12.1 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) Mpv17_PMP22 PF04117.7 KND91311.1 - 3.4e-28 97.0 5.9 5.7e-28 96.3 4.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1582 PF07621.6 KND91311.1 - 0.17 11.9 0.3 11 6.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) Iso_dh PF00180.15 KND91312.1 - 1.4e-96 323.5 0.0 2.4e-96 322.7 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_1_2 PF00155.16 KND91313.1 - 3.6e-29 101.8 0.0 4.6e-26 91.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KND91313.1 - 0.011 14.4 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Allinase Aminotran_5 PF00266.14 KND91313.1 - 0.071 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KND91313.1 - 0.095 10.9 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KND91313.1 - 0.11 11.4 0.0 0.28 10.1 0.0 1.7 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SNARE PF05739.14 KND91315.1 - 4.5e-11 42.2 7.0 4.5e-11 42.2 4.9 3.1 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KND91315.1 - 1.4e-05 25.1 5.1 1.4e-05 25.1 3.5 2.7 2 1 0 2 2 2 1 Syntaxin DUF912 PF06024.7 KND91315.1 - 0.0027 17.7 1.8 0.0027 17.7 0.1 1.9 2 0 0 2 2 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 KND91315.1 - 0.016 14.6 0.7 0.038 13.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Baculo_11_kDa PF06143.6 KND91315.1 - 0.017 14.4 0.5 0.06 12.7 0.3 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Allexi_40kDa PF05549.6 KND91315.1 - 0.02 14.1 2.9 0.044 13.0 0.1 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Mid2 PF04478.7 KND91315.1 - 0.076 12.4 3.1 0.16 11.3 2.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MCPsignal PF00015.16 KND91315.1 - 0.077 12.5 11.1 0.13 11.7 4.0 2.6 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2839 PF10999.3 KND91315.1 - 0.11 12.5 0.6 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Chordopox_A33R PF05966.7 KND91315.1 - 0.12 11.1 1.3 0.16 10.6 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A33R protein ODV-E18 PF10717.4 KND91315.1 - 0.13 11.7 0.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Vac_Fusion PF02346.11 KND91315.1 - 0.16 11.4 2.2 8.2 5.9 0.0 3.3 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Herpes_U30 PF04523.8 KND91315.1 - 0.17 9.3 3.6 0.22 8.9 2.5 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 FUSC PF04632.7 KND91315.1 - 0.22 9.9 8.8 0.39 9.0 6.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin_2 PF14523.1 KND91315.1 - 0.59 10.1 8.8 0.24 11.4 2.9 2.2 2 0 0 2 2 2 0 Syntaxin-like protein EphA2_TM PF14575.1 KND91315.1 - 0.63 10.4 2.4 0.44 10.9 0.2 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3753 PF12575.3 KND91315.1 - 1.4 8.7 4.2 2.8 7.8 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Rifin_STEVOR PF02009.11 KND91315.1 - 1.5 8.4 9.9 3.1 7.3 6.6 1.6 1 1 0 1 1 1 0 Rifin/stevor family V-SNARE PF05008.10 KND91315.1 - 5.5 7.2 12.4 1.8 8.7 0.5 3.7 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Shisa PF13908.1 KND91315.1 - 8.6 6.4 5.9 4.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Glyco_hydro_18 PF00704.23 KND91316.1 - 3.1e-72 243.8 0.0 3.6e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Epimerase PF01370.16 KND91318.1 - 6.7e-13 48.6 0.0 4.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KND91318.1 - 0.00017 21.9 0.0 0.00054 20.2 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KND91318.1 - 0.00022 20.2 0.0 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 KND91318.1 - 0.00025 20.3 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KND91318.1 - 0.00026 20.1 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KND91318.1 - 0.0014 18.6 0.0 0.0036 17.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND91318.1 - 0.0064 15.2 0.0 0.22 10.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PG_binding_1 PF01471.13 KND91321.1 - 0.00019 21.3 0.0 0.25 11.3 0.0 2.7 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Sigma70_ner PF04546.8 KND91321.1 - 0.0055 16.3 0.9 0.011 15.4 0.6 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region Tropomyosin_1 PF12718.2 KND91321.1 - 0.0088 15.8 1.6 0.0088 15.8 1.1 2.1 1 1 1 2 2 2 1 Tropomyosin like MAP65_ASE1 PF03999.7 KND91321.1 - 0.011 14.4 1.7 0.016 13.8 1.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) K-box PF01486.12 KND91321.1 - 0.017 14.8 0.5 0.041 13.6 0.4 1.6 1 0 0 1 1 1 0 K-box region AAA_13 PF13166.1 KND91321.1 - 0.02 13.3 2.0 0.029 12.8 1.4 1.1 1 0 0 1 1 1 0 AAA domain PspA_IM30 PF04012.7 KND91321.1 - 0.025 13.9 5.1 0.046 13.0 3.6 1.3 1 0 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.6 KND91321.1 - 0.06 12.0 2.1 0.13 10.8 1.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 KND91321.1 - 0.064 10.9 8.0 0.1 10.3 5.6 1.2 1 0 0 1 1 1 0 Myosin tail Laminin_II PF06009.7 KND91321.1 - 0.073 12.8 3.0 0.18 11.5 1.4 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF2937 PF11157.3 KND91321.1 - 0.12 11.6 0.2 5.2 6.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) SlyX PF04102.7 KND91321.1 - 0.2 12.0 6.3 1.4 9.3 0.9 2.6 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 KND91321.1 - 0.27 11.0 1.7 0.51 10.1 0.4 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 KND91321.1 - 0.38 10.5 3.3 1 9.1 2.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF812 PF05667.6 KND91321.1 - 0.41 9.0 3.4 0.69 8.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 KND91321.1 - 0.43 9.5 4.1 0.72 8.8 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 KND91321.1 - 1.3 9.1 5.8 6.7 6.9 0.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pribosyltran PF00156.22 KND91322.1 - 8.3e-17 61.0 0.0 1.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KND91322.1 - 0.0061 15.7 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 KND91322.1 - 0.074 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like MFS_1_like PF12832.2 KND91323.1 - 1.5e-15 56.7 0.5 8e-15 54.4 0.0 2.6 2 0 0 2 2 2 1 MFS_1 like family Glyco_hydro_47 PF01532.15 KND91325.1 - 1.6e-129 432.4 0.0 2e-129 432.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans PF04082.13 KND91327.1 - 1.5e-07 30.5 0.1 2.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91327.1 - 3.1e-06 26.9 10.2 3.1e-06 26.9 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Tim10_DDP PF02953.10 KND91328.1 - 2.4e-22 77.9 3.5 2.9e-22 77.7 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KND91328.1 - 0.041 13.3 2.8 0.046 13.1 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) bZIP_1 PF00170.16 KND91328.1 - 0.073 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor RL11D PF11088.3 KND91328.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Aldedh PF00171.17 KND91329.1 - 1.6e-139 465.1 0.3 2e-139 464.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KND91329.1 - 0.00045 19.5 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.9 KND91329.1 - 0.0027 16.4 0.0 0.014 14.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ribosomal_S5 PF00333.15 KND91330.1 - 2.7e-27 94.3 2.5 2.7e-27 94.3 1.7 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KND91330.1 - 4.1e-21 74.0 0.1 1.1e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Cyclin_N PF00134.18 KND91332.1 - 3.8e-34 116.9 0.2 6.2e-34 116.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KND91332.1 - 1.2e-10 41.3 0.1 3.9e-10 39.6 0.1 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.20 KND91334.1 - 7.7e-60 202.2 0.0 9.9e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91334.1 - 1.4e-26 93.1 0.0 2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND91334.1 - 1.4e-06 27.4 0.0 1.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND91334.1 - 0.0032 16.5 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND91334.1 - 0.0047 16.6 0.0 0.25 11.0 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Cation_efflux PF01545.16 KND91335.1 - 9.7e-79 264.3 5.6 3.4e-78 262.6 3.9 1.7 1 1 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 KND91335.1 - 0.0057 15.6 0.6 0.0057 15.6 0.4 2.3 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component HHH PF00633.18 KND91336.1 - 0.00069 19.1 0.1 0.0023 17.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Bap31 PF05529.7 KND91337.1 - 2.2e-54 183.8 16.8 8e-54 182.0 11.6 1.7 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF192 PF02643.10 KND91337.1 - 0.0074 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Tmemb_55A PF09788.4 KND91337.1 - 0.08 12.0 0.4 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A DUF4446 PF14584.1 KND91337.1 - 0.12 12.1 1.6 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Viral_P18 PF04521.8 KND91337.1 - 0.21 11.0 2.6 0.35 10.3 1.8 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 KND91337.1 - 2.3 7.7 5.8 1.3 8.5 0.8 2.6 2 1 1 3 3 3 0 Septum formation initiator Methyltransf_16 PF10294.4 KND91339.1 - 2.3e-18 66.2 0.0 3.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KND91339.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND91339.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KND91339.1 - 0.1 13.1 0.2 0.2 12.2 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KND91339.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RNA_pol_N PF01194.12 KND91341.1 - 8.7e-29 99.3 1.0 1.2e-28 98.9 0.7 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KND91341.1 - 0.035 14.2 0.2 0.054 13.5 0.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mqo PF06039.10 KND91341.1 - 0.11 10.6 0.0 0.13 10.3 0.0 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) DIOX_N PF14226.1 KND91342.1 - 2.1e-21 76.6 0.0 1.8e-20 73.6 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND91342.1 - 9.2e-13 48.3 0.0 2.7e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 KND91342.1 - 7.1e-10 38.3 4.8 4.7e-06 26.2 0.3 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-met2 PF12907.2 KND91343.1 - 1.9e-18 66.1 1.8 1.9e-18 66.1 1.3 1.5 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.9 KND91343.1 - 7.6e-07 29.7 12.3 1.5e-06 28.7 8.6 1.5 1 0 0 1 1 1 1 4F5 protein family HypA PF01155.14 KND91343.1 - 0.012 15.3 1.0 0.014 15.0 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family BIR PF00653.16 KND91343.1 - 0.015 15.6 1.2 0.02 15.3 0.8 1.1 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Rpr2 PF04032.11 KND91343.1 - 0.029 14.2 1.0 0.036 13.9 0.7 1.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RRN7 PF11781.3 KND91343.1 - 0.043 13.3 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 KND91343.1 - 0.1 12.2 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain CLAG PF03805.8 KND91343.1 - 0.14 9.4 2.9 0.16 9.3 2.0 1.0 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein zf-Di19 PF05605.7 KND91343.1 - 0.59 10.3 2.6 4.1 7.5 1.8 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding NACHT PF05729.7 KND91344.1 - 9.2e-09 35.1 0.0 2.7e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KND91344.1 - 4.6e-05 23.4 0.6 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KND91344.1 - 0.01 15.9 0.1 0.08 13.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 KND91344.1 - 0.025 14.8 0.0 0.08 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND91344.1 - 0.028 14.5 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KND91344.1 - 0.055 13.6 0.2 0.23 11.6 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 KND91344.1 - 0.11 11.8 0.1 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KND91344.1 - 0.19 11.2 0.1 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KND91344.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 KND91344.1 - 0.61 9.0 5.3 0.44 9.4 0.9 2.1 1 1 0 2 2 2 0 KAP family P-loop domain ABC_membrane_2 PF06472.10 KND91345.1 - 2.8e-96 321.9 4.6 6.3e-96 320.8 0.2 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KND91345.1 - 1.6e-16 60.8 0.0 3.9e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND91345.1 - 0.0021 18.0 0.2 0.0067 16.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KND91345.1 - 0.0033 16.6 0.1 0.0056 15.8 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 KND91345.1 - 0.0043 17.4 4.8 0.049 13.9 3.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND91345.1 - 0.023 15.5 0.1 0.21 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KND91345.1 - 0.035 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KND91345.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 KND91345.1 - 0.071 12.5 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KND91345.1 - 0.12 12.5 0.0 0.38 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Herpes_US9 PF06072.6 KND91346.1 - 0.17 11.7 0.5 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RNase_P_p30 PF01876.11 KND91349.1 - 1e-44 151.3 0.0 1.7e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 FAD_binding_3 PF01494.14 KND91350.1 - 2.5e-16 59.6 0.0 2.9e-15 56.1 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND91350.1 - 8.4e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND91350.1 - 5e-05 22.3 0.0 8.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND91350.1 - 0.00033 20.9 0.0 0.00095 19.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND91350.1 - 0.0031 16.0 0.0 0.0043 15.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KND91350.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KND91350.1 - 0.0086 14.9 0.1 0.017 14.0 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KND91350.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND91350.1 - 0.012 14.7 0.1 0.05 12.6 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase SE PF08491.5 KND91350.1 - 0.044 12.6 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 KND91350.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S8 PF00410.14 KND91351.1 - 2.4e-23 82.3 0.0 3.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Cornichon PF03311.9 KND91353.1 - 1.6e-37 128.4 18.1 1.3e-34 119.0 4.9 2.0 1 1 1 2 2 2 2 Cornichon protein Peptidase_M24 PF00557.19 KND91354.1 - 7.1e-37 126.9 0.1 1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KND91354.1 - 0.00065 19.5 4.2 0.00065 19.5 2.9 3.6 4 0 0 4 4 4 1 MYND finger Prefoldin_3 PF13758.1 KND91355.1 - 4e-29 100.3 0.9 4e-29 100.3 0.6 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KND91355.1 - 1.5e-19 70.7 2.3 2.8e-18 66.6 0.4 5.5 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.15 KND91355.1 - 0.78 9.5 9.5 0.3 10.8 0.1 3.5 4 0 0 4 4 4 0 Prefoldin subunit Mnd1 PF03962.10 KND91355.1 - 1 8.9 6.0 5.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Mnd1 family Prefoldin PF02996.12 KND91355.1 - 2.5 7.7 5.4 0.71 9.5 0.1 2.5 3 0 0 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.8 KND91355.1 - 6 7.6 6.8 1e+02 3.7 0.1 3.6 4 0 0 4 4 4 0 Occludin homology domain Mur_ligase_M PF08245.7 KND91356.1 - 0.012 15.6 0.0 0.15 12.0 0.0 2.3 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.16 KND91356.1 - 0.035 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Ribosomal_S17 PF00366.15 KND91357.1 - 7.9e-30 102.7 0.5 1.2e-29 102.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Mt_ATP-synt_D PF05873.7 KND91358.1 - 0.011 15.3 0.5 0.029 14.0 0.3 1.7 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1719 PF08224.6 KND91358.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Bcr-Abl_Oligo PF09036.5 KND91358.1 - 0.16 11.9 2.0 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Syja_N PF02383.13 KND91359.1 - 3.2e-89 298.8 0.1 4e-89 298.5 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Mitofilin PF09731.4 KND91361.1 - 8.1e-143 477.1 14.1 1.8e-142 475.9 9.8 1.5 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Mur_ligase_C PF02875.16 KND91361.1 - 0.0015 18.5 0.0 0.0072 16.3 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain PilJ PF13675.1 KND91361.1 - 0.15 12.3 5.9 0.5 10.7 0.7 3.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term 4HB_MCP_1 PF12729.2 KND91361.1 - 0.66 9.2 12.1 0.43 9.8 6.9 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Ras PF00071.17 KND91362.1 - 5.6e-55 185.1 0.1 7.1e-55 184.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND91362.1 - 7e-18 65.2 0.1 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND91362.1 - 4.2e-12 45.6 0.0 5.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND91362.1 - 3.4e-07 29.8 0.0 4.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KND91362.1 - 2.6e-05 23.4 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND91362.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Spc7_N PF15402.1 KND91364.1 - 9.7e-244 811.5 77.0 1.9e-243 810.5 53.4 1.5 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KND91364.1 - 2.5e-118 394.5 4.6 2.5e-118 394.5 3.2 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KND91364.1 - 1.2e-18 66.5 0.1 2.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Spc7_C2 Baculo_PEP_C PF04513.7 KND91364.1 - 0.0028 17.4 0.2 0.0076 16.0 0.1 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KND91364.1 - 3.7 7.0 17.1 0.059 12.9 5.8 2.5 2 0 0 2 2 2 0 IncA protein GFA PF04828.9 KND91365.1 - 3.8e-16 58.8 2.5 6.6e-16 58.0 1.8 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_transf_28 PF03033.15 KND91367.1 - 8.9e-21 74.1 0.2 1.8e-19 69.8 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KND91367.1 - 5.5e-05 21.9 0.0 9.2e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KND91367.1 - 0.00037 20.1 0.0 0.00089 18.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 KND91367.1 - 0.00047 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain TH1 PF04858.8 KND91367.1 - 0.14 10.3 0.1 0.23 9.5 0.1 1.2 1 0 0 1 1 1 0 TH1 protein Sec61_beta PF03911.11 KND91368.1 - 3.6e-20 71.4 1.6 5.1e-20 70.9 1.1 1.2 1 0 0 1 1 1 1 Sec61beta family KdpC PF02669.10 KND91368.1 - 0.23 11.1 2.0 0.46 10.1 1.4 1.5 1 1 0 1 1 1 0 K+-transporting ATPase, c chain NIF PF03031.13 KND91369.1 - 1.1e-51 174.6 0.2 1.6e-51 174.1 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KND91369.1 - 0.18 11.9 0.2 1.8 8.7 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-DHHC PF01529.15 KND91370.1 - 3.4e-28 98.2 4.4 3.4e-28 98.2 3.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KND91370.1 - 0.016 15.0 0.4 0.048 13.4 0.2 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily FYVE PF01363.16 KND91370.1 - 0.11 12.3 7.5 0.23 11.4 5.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 KND91370.1 - 0.85 9.4 10.9 1.5 8.6 7.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon F-box-like PF12937.2 KND91372.1 - 0.00024 20.7 0.4 0.00024 20.7 0.3 2.3 2 0 0 2 2 2 1 F-box-like PRANC PF09372.5 KND91372.1 - 0.038 13.9 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 PRANC domain zf-P11 PF03854.9 KND91372.1 - 0.52 9.8 4.7 0.26 10.7 0.5 2.4 2 0 0 2 2 2 0 P-11 zinc finger UPF0183 PF03676.9 KND91373.1 - 2.6e-45 154.6 0.0 2.8e-30 105.1 0.0 4.2 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Rad60-SLD_2 PF13881.1 KND91373.1 - 0.055 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FAD-oxidase_C PF02913.14 KND91374.1 - 6.7e-59 199.1 1.0 7.6e-59 199.0 0.1 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KND91374.1 - 1.7e-35 121.4 0.0 3.4e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 KND91375.1 - 8.3e-25 86.4 1.3 2.5e-24 84.9 0.5 2.2 2 0 0 2 2 2 1 Clr5 domain ECH PF00378.15 KND91376.1 - 6.5e-41 140.0 0.0 8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Glyco_tranf_2_3 PF13641.1 KND91378.1 - 1.8e-19 70.4 0.1 2.5e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KND91378.1 - 2.8e-07 29.9 0.1 8.1e-07 28.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KND91378.1 - 9e-07 28.7 0.0 2.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF420 PF04238.7 KND91378.1 - 0.0033 17.3 1.7 0.0076 16.2 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF420) GWT1 PF06423.7 KND91380.1 - 2.3e-43 147.5 2.6 2.3e-43 147.5 1.8 2.0 2 0 0 2 2 2 1 GWT1 tRNA-synt_2c PF01411.14 KND91382.1 - 5.1e-212 705.0 0.1 8.6e-212 704.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KND91382.1 - 2.1e-17 62.7 0.3 6.8e-17 61.0 0.2 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KND91382.1 - 0.0017 18.0 0.0 0.0065 16.1 0.0 2.1 1 0 0 1 1 1 1 DHHA1 domain Fer4_12 PF13353.1 KND91382.1 - 0.11 12.6 0.2 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Methyltransf_28 PF02636.12 KND91383.1 - 1.1e-37 129.7 0.0 2.2e-37 128.8 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KND91383.1 - 0.028 13.3 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PALP PF00291.20 KND91384.1 - 1.1e-55 189.0 3.4 1.3e-55 188.7 2.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIS_M PF07500.9 KND91385.1 - 4.1e-25 88.0 0.2 9.1e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain XPG_I PF00867.13 KND91385.1 - 2.2e-20 72.5 0.1 7.6e-20 70.7 0.1 2.0 1 0 0 1 1 1 1 XPG I-region TFIIS_C PF01096.13 KND91385.1 - 3.7e-18 64.8 7.2 7.4e-18 63.8 5.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KND91385.1 - 3e-12 45.8 0.2 6.7e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain 5_3_exonuc PF01367.15 KND91385.1 - 0.042 14.0 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold XPG_N PF00752.12 KND91386.1 - 1.5e-33 115.0 0.0 3.5e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain UIM PF02809.15 KND91386.1 - 0.1 12.1 0.1 0.1 12.1 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin interaction motif LSM PF01423.17 KND91387.1 - 5.7e-09 35.3 0.0 7.1e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND91387.1 - 0.05 13.5 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF775 PF05603.7 KND91388.1 - 6e-49 166.3 0.0 7.2e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 KND91389.1 - 5.8e-11 42.1 0.0 9.7e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ThiF PF00899.16 KND91390.1 - 3e-10 40.0 0.0 1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 ThiF family ThiF PF00899.16 KND91391.1 - 3e-10 40.0 0.0 1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 ThiF family GDA1_CD39 PF01150.12 KND91392.1 - 2.2e-96 323.0 0.0 3e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TT_ORF1 PF02956.9 KND91392.1 - 0.29 9.5 0.5 0.44 8.9 0.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 Asr PF06392.6 KND91392.1 - 7.6 7.0 9.8 0.082 13.2 1.2 1.9 2 0 0 2 2 2 0 Acid shock protein repeat adh_short PF00106.20 KND91393.1 - 5.3e-34 117.5 0.0 7.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND91393.1 - 1.1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND91393.1 - 1.7e-13 50.9 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KND91393.1 - 0.00064 19.4 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 KND91393.1 - 0.057 12.3 0.0 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase MFS_1 PF07690.11 KND91394.1 - 2.5e-34 118.5 44.6 9.7e-34 116.6 30.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND91394.1 - 1.3e-10 40.5 13.5 1.3e-10 40.5 9.3 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter XPG_I_2 PF12813.2 KND91395.1 - 5.4e-49 166.8 0.0 1e-48 166.0 0.0 1.4 2 0 0 2 2 2 1 XPG domain containing XPG_I PF00867.13 KND91395.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 XPG I-region Pribosyltran_N PF13793.1 KND91396.1 - 2.5e-38 130.3 0.0 5.1e-36 122.9 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KND91396.1 - 1.7e-33 115.8 0.0 4.3e-28 98.3 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KND91396.1 - 1.3e-05 24.8 0.9 0.0046 16.6 0.0 3.0 4 0 0 4 4 4 2 Phosphoribosyl transferase domain Bud13 PF09736.4 KND91397.1 - 5.1e-43 146.7 8.0 5.1e-43 146.7 5.5 2.3 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF2229 PF09989.4 KND91397.1 - 1.5 8.2 3.9 2.6 7.4 2.7 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PAP_assoc PF03828.14 KND91398.1 - 6.9e-15 54.7 0.0 7.7e-14 51.3 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase SAPS PF04499.10 KND91398.1 - 0.0093 14.6 0.1 0.013 14.1 0.1 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein NTP_transf_2 PF01909.18 KND91398.1 - 0.025 14.8 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Nop14 PF04147.7 KND91398.1 - 4.2 5.1 14.7 6.3 4.5 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Borrelia_P83 PF05262.6 KND91398.1 - 5.2 5.2 11.7 7.9 4.6 8.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 KND91398.1 - 8 4.3 9.0 14 3.5 6.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SUR7 PF06687.7 KND91399.1 - 6.6e-34 117.3 15.1 8e-34 117.0 10.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family RCR PF12273.3 KND91399.1 - 0.00016 22.2 0.1 0.00037 21.0 0.0 1.7 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1049 PF06305.6 KND91399.1 - 0.076 12.4 0.0 0.076 12.4 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) WD40 PF00400.27 KND91400.1 - 7.6e-17 60.4 11.2 1.5e-09 37.3 0.0 9.6 10 0 0 10 10 10 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KND91400.1 - 0.0035 16.1 0.5 1.2 7.7 0.0 4.1 4 2 0 4 4 4 2 Nup133 N terminal like TFIIA PF03153.8 KND91402.1 - 7.5e-77 259.7 4.7 8.6e-77 259.5 3.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 KND91402.1 - 0.13 10.9 4.3 0.21 10.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kelch_4 PF13418.1 KND91403.1 - 6.5e-26 89.8 5.7 1.3e-08 34.4 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KND91403.1 - 1.3e-24 85.6 1.0 2.6e-07 30.4 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KND91403.1 - 9.9e-24 82.4 1.5 4.3e-05 23.4 0.0 5.1 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KND91403.1 - 3.1e-21 74.6 0.0 2.3e-05 23.8 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 KND91403.1 - 1.2e-20 73.0 5.8 9.7e-08 31.9 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KND91403.1 - 2.2e-19 68.3 2.5 0.00043 19.9 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KND91403.1 - 3.6e-09 36.5 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 KND91403.1 - 0.21 10.7 0.0 0.9 8.6 0.0 2.0 1 1 1 2 2 2 0 Cortical protein marker for cell polarity zf-H2C2_2 PF13465.1 KND91404.1 - 2.7e-05 24.2 7.3 0.015 15.5 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND91404.1 - 0.00036 20.6 10.0 0.44 11.0 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KND91404.1 - 0.0018 18.5 13.1 0.4 11.1 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KND91404.1 - 0.01 15.9 7.7 0.027 14.5 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Kelch_3 PF13415.1 KND91405.1 - 6.6e-44 147.1 17.1 1.8e-08 34.3 0.0 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KND91405.1 - 1.9e-42 142.7 21.0 2.4e-10 40.0 0.2 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KND91405.1 - 4.9e-40 134.8 17.9 5e-09 35.5 0.6 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KND91405.1 - 1.4e-38 130.2 16.0 1.9e-07 30.8 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KND91405.1 - 3.7e-34 115.5 17.1 8.8e-07 28.8 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KND91405.1 - 3.8e-31 105.6 16.0 4e-07 29.5 0.2 6.5 6 0 0 6 6 6 6 Kelch motif ADH_N PF08240.7 KND91407.1 - 7.9e-18 64.2 1.3 1.2e-17 63.6 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND91407.1 - 1.3e-15 57.0 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND91407.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_G PF04718.10 KND91408.1 - 3e-29 101.6 1.3 4.1e-29 101.2 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Methyltransf_23 PF13489.1 KND91409.1 - 0.00031 20.5 0.0 0.00051 19.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain LEA_3 PF03242.8 KND91409.1 - 0.077 13.2 0.1 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein RasGAP PF00616.14 KND91410.1 - 2.9e-40 138.0 0.0 1.6e-39 135.6 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KND91410.1 - 1e-18 67.4 0.4 3.3e-18 65.7 0.3 2.0 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.22 KND91410.1 - 5.2e-12 44.2 42.6 0.12 12.0 1.4 12.3 15 0 0 15 15 15 7 IQ calmodulin-binding motif CH PF00307.26 KND91410.1 - 1e-09 38.3 0.0 3.3e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.10 KND91410.1 - 0.41 10.1 6.5 0.11 12.0 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF155 PF02582.9 KND91411.1 - 8.3e-60 201.6 0.1 1.2e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.12 KND91411.1 - 0.16 11.1 0.1 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain E1-E2_ATPase PF00122.15 KND91412.1 - 1.3e-52 178.1 0.0 2.6e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND91412.1 - 4.1e-45 154.8 1.7 8.7e-45 153.7 1.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KND91412.1 - 9e-44 147.4 0.1 3.4e-11 43.1 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KND91412.1 - 4.4e-14 53.0 0.0 2.8e-13 50.4 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND91412.1 - 9.5e-07 28.6 1.4 2.8e-05 23.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aa_trans PF01490.13 KND91414.1 - 1.6e-15 56.4 26.4 1.1e-08 34.0 6.9 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein UDG PF03167.14 KND91415.1 - 2.9e-21 75.5 0.0 4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.13 KND91416.1 - 2.3e-55 187.8 0.0 3.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KND91416.1 - 0.03 14.4 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain DEAD PF00270.24 KND91417.1 - 9e-25 87.1 1.4 2.8e-23 82.2 0.0 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND91417.1 - 2.6e-21 75.2 0.0 6.9e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND91417.1 - 9e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Vps8 PF12816.2 KND91418.1 - 5.7e-72 241.0 0.0 1.1e-71 240.2 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.7 KND91418.1 - 2.4e-40 137.0 0.0 5.2e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.15 KND91418.1 - 0.00085 18.9 0.2 0.55 9.8 0.0 3.7 5 0 0 5 5 5 2 Region in Clathrin and VPS DUF2401 PF10287.4 KND91419.1 - 4.5e-82 275.0 1.0 6.8e-82 274.4 0.7 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 KND91419.1 - 2.9e-16 59.3 0.0 8.3e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Peptidase_M23 PF01551.17 KND91419.1 - 0.095 12.7 0.5 7.1 6.7 0.1 2.7 1 1 2 3 3 3 0 Peptidase family M23 DUF3955 PF13127.1 KND91419.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) RCC1_2 PF13540.1 KND91419.1 - 0.47 10.1 3.7 22 4.8 0.2 3.7 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat HATPase_c PF02518.21 KND91421.1 - 2.9e-21 75.2 0.1 5.3e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KND91421.1 - 7.5e-21 74.2 0.1 1.7e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KND91421.1 - 1.6e-09 38.0 0.0 1.7e-08 34.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KND91421.1 - 2.3e-09 37.2 0.0 0.00015 21.7 0.0 3.0 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KND91421.1 - 2.2e-08 33.9 0.2 7.7e-08 32.2 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 KND91421.1 - 9.6e-05 22.9 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 2 GAF domain PAS PF00989.19 KND91421.1 - 0.00017 21.3 0.0 0.0028 17.4 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 KND91421.1 - 0.0015 18.3 0.1 0.0088 15.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PH_6 PF15406.1 KND91422.1 - 1.2e-33 115.5 0.5 1.2e-33 115.5 0.3 3.3 3 1 0 3 3 3 1 Pleckstrin homology domain Capsid-VNN PF11729.3 KND91422.1 - 0.13 11.2 1.5 0.26 10.1 1.1 1.5 1 0 0 1 1 1 0 nodavirus capsid protein Metallophos PF00149.23 KND91424.1 - 3.8e-38 130.9 0.3 3.8e-38 130.9 0.2 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Aldedh PF00171.17 KND91426.1 - 2.9e-166 553.4 0.6 3.3e-166 553.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XK-related PF09815.4 KND91428.1 - 0.088 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 XK-related protein META PF03724.11 KND91429.1 - 0.14 12.0 0.0 1.3 8.9 0.0 2.3 1 1 0 2 2 2 0 META domain DUF3752 PF12572.3 KND91430.1 - 6.7e-37 126.9 5.2 1.1e-36 126.2 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) DUF3682 PF12446.3 KND91430.1 - 1.1 9.5 17.4 2.4 8.4 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3682) tRNA-synt_2 PF00152.15 KND91431.1 - 3.2e-70 236.5 0.0 2.7e-69 233.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND91431.1 - 5.5e-09 35.7 0.2 9.4e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KND91431.1 - 1.6e-06 27.5 0.0 0.00094 18.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KND91431.1 - 0.0049 16.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Actin PF00022.14 KND91432.1 - 2e-143 477.5 0.0 2.3e-143 477.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KND91432.1 - 7.6e-06 24.7 0.0 0.012 14.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF2454 PF10521.4 KND91433.1 - 1e-46 159.2 0.0 3.3e-46 157.5 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2454) HEAT PF02985.17 KND91433.1 - 0.0023 17.8 0.5 0.19 11.8 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat PolyA_pol PF01743.15 KND91434.1 - 3.6e-24 85.3 0.1 1.1e-23 83.8 0.1 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KND91434.1 - 6.5e-11 41.6 0.1 1.5e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Sec7 PF01369.15 KND91435.1 - 4.1e-58 196.2 0.0 8.4e-58 195.1 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KND91435.1 - 7.7e-17 61.2 0.0 6.5e-10 38.6 0.0 2.7 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Syja_N PF02383.13 KND91436.1 - 1.2e-88 296.9 0.0 2.8e-88 295.7 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain WYL PF13280.1 KND91436.1 - 0.035 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 WYL domain Staphostatin_B PF09023.5 KND91436.1 - 0.2 11.4 2.1 18 5.2 0.0 3.3 2 1 1 3 3 3 0 Staphostatin B Anp1 PF03452.9 KND91438.1 - 1e-123 411.7 2.3 1.8e-122 407.6 0.0 2.1 2 0 0 2 2 2 1 Anp1 Rad54_N PF08658.5 KND91438.1 - 0.077 12.7 2.3 0.15 11.8 1.6 1.4 1 0 0 1 1 1 0 Rad54 N terminal zf-C3HC4_3 PF13920.1 KND91439.1 - 5.7e-07 29.1 13.5 9.4e-07 28.4 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 KND91439.1 - 2.5 8.3 8.4 6.3 7.0 5.9 1.6 1 0 0 1 1 1 0 FAM24 family RNase_PH PF01138.16 KND91440.1 - 1.1e-25 90.5 0.0 2.5e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNA_pol_Rpb8 PF03870.10 KND91441.1 - 4.3e-36 124.1 0.0 4.9e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 tRNA_int_endo PF01974.12 KND91442.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PAXNEB PF05625.6 KND91443.1 - 2e-95 319.7 0.0 2.2e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Asp PF00026.18 KND91444.1 - 6.9e-63 212.7 0.0 1.1e-62 212.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease GTP_EFTU PF00009.22 KND91444.1 - 1.1e-55 188.0 0.1 1.8e-55 187.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KND91444.1 - 1.2e-30 105.1 0.0 2.3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KND91444.1 - 2.5e-29 101.2 0.0 6e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KND91444.1 - 1.8e-22 79.0 0.0 4e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND91444.1 - 5.5e-13 48.8 0.1 1.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TAXi_N PF14543.1 KND91444.1 - 6.5e-09 35.9 0.0 5.8e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KND91444.1 - 0.0035 16.9 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Ribosomal_L23eN PF03939.8 KND91445.1 - 1e-19 70.2 8.7 1e-19 70.2 6.0 3.0 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KND91445.1 - 3.2e-17 62.2 1.6 6.5e-17 61.2 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 P2 PF07194.6 KND91445.1 - 0.076 12.8 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain DUF3321 PF11968.3 KND91447.1 - 6.9e-83 277.6 0.0 9.7e-83 277.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KND91447.1 - 0.0027 17.4 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CorA PF01544.13 KND91448.1 - 9.4e-43 146.3 0.0 1.3e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 KND91449.1 - 8.6e-21 73.0 3.4 1.1e-20 72.7 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Toxin_1 PF00087.16 KND91449.1 - 0.036 14.4 0.7 0.053 13.9 0.5 1.2 1 0 0 1 1 1 0 Snake toxin SPC12 PF06645.8 KND91450.1 - 9.5e-27 92.6 0.0 1.1e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) NAD_binding_8 PF13450.1 KND91452.1 - 2.6e-11 43.3 2.4 3.7e-11 42.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND91452.1 - 4.7e-08 32.3 3.7 2.1e-06 26.9 0.3 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND91452.1 - 5.8e-08 33.0 0.2 0.00049 20.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND91452.1 - 4.4e-07 29.9 0.0 7.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND91452.1 - 1.1e-06 28.0 0.4 1.9e-05 23.9 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND91452.1 - 3.7e-06 26.0 1.3 6e-06 25.3 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND91452.1 - 9.3e-06 24.3 0.3 0.00022 19.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KND91452.1 - 2.2e-05 23.6 0.1 6.3e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KND91452.1 - 0.00039 20.5 0.5 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KND91452.1 - 0.00046 19.3 0.2 0.002 17.2 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KND91452.1 - 0.00052 18.7 0.3 0.0013 17.3 0.2 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 KND91452.1 - 0.0014 17.5 0.2 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KND91452.1 - 0.0038 17.0 0.1 0.02 14.7 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KND91452.1 - 0.024 13.7 1.4 0.3 10.0 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KND91452.1 - 0.043 12.6 0.6 0.093 11.5 0.4 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KND91452.1 - 0.049 12.5 0.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-rbx1 PF12678.2 KND91453.1 - 6.1e-35 119.1 13.5 7.7e-35 118.8 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KND91453.1 - 3.1e-17 62.1 9.8 4e-17 61.8 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KND91453.1 - 7.7e-07 28.8 11.7 5.1e-06 26.2 8.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KND91453.1 - 0.0018 17.9 11.5 0.031 13.9 8.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND91453.1 - 0.0035 16.9 9.1 0.51 10.0 6.6 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND91453.1 - 0.056 13.4 12.6 0.057 13.4 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KND91453.1 - 0.81 9.7 9.2 4.6 7.2 6.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 KND91453.1 - 0.95 9.2 11.6 9.4 6.0 8.0 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 KND91453.1 - 1.3 9.2 10.9 1e+02 3.1 7.6 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 KND91453.1 - 1.4 8.6 6.9 34 4.2 4.8 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 KND91453.1 - 1.4 8.9 10.3 4.7 7.2 7.1 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain Tyr-DNA_phospho PF06087.7 KND91454.1 - 2.9e-70 237.1 0.0 3.4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KND91454.1 - 0.00025 20.8 0.0 0.001 18.7 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 KND91454.1 - 0.0019 17.5 1.2 0.0019 17.5 0.8 2.4 3 0 0 3 3 3 1 Ubiquitin interaction motif PNRC PF15365.1 KND91455.1 - 2.8e-06 27.2 4.2 2.8e-06 27.2 2.9 4.7 5 1 0 5 5 5 2 Proline-rich nuclear receptor coactivator Methyltransf_18 PF12847.2 KND91456.1 - 4.2e-14 53.0 0.1 7.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND91456.1 - 1.7e-12 47.3 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND91456.1 - 5.9e-10 38.6 0.0 8.5e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KND91456.1 - 9.9e-10 38.7 0.1 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91456.1 - 1.2e-08 35.2 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND91456.1 - 3.5e-08 33.7 0.2 5.7e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND91456.1 - 2.2e-06 27.3 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND91456.1 - 5e-06 26.0 0.0 9.4e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KND91456.1 - 1.1e-05 25.3 0.2 2.2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KND91456.1 - 2e-05 24.0 0.0 3.1e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.12 KND91456.1 - 0.0011 18.0 0.0 0.0042 16.1 0.0 1.9 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_15 PF09445.5 KND91456.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.9 KND91456.1 - 0.032 13.4 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 KND91456.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KND91456.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 KND91456.1 - 0.09 11.6 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Pkinase_Tyr PF07714.12 KND91457.1 - 6.1e-14 51.7 0.0 1.9e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KND91457.1 - 1.8e-13 50.2 0.0 1.6e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.9 KND91457.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND91457.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 RIO1 family APH PF01636.18 KND91457.1 - 0.18 11.5 1.2 2.1 7.9 0.7 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 KND91459.1 - 1.4e-43 145.2 11.2 1.4e-08 34.2 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 KND91459.1 - 1.5e-43 147.5 0.3 3.2e-43 146.4 0.2 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 KND91459.1 - 4.6e-34 117.4 0.0 7.5e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 KND91460.1 - 6.1e-36 121.0 8.7 8.3e-13 47.6 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat VWA_3 PF13768.1 KND91461.1 - 1.8e-27 95.9 0.0 3.7e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KND91461.1 - 8e-18 64.2 0.0 1.8e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KND91461.1 - 5.5e-12 46.1 0.0 4.1e-11 43.2 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 KND91461.1 - 2.5e-07 30.0 0.0 6.8e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KND91461.1 - 3.5e-07 30.0 0.0 6.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KND91461.1 - 0.0027 16.8 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Coleoptericin PF06286.6 KND91464.1 - 0.33 10.8 3.2 0.18 11.6 1.1 1.4 1 1 0 1 1 1 0 Coleoptericin APH PF01636.18 KND91465.1 - 2.2e-11 43.9 0.1 4.1e-10 39.8 0.1 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND91465.1 - 0.0083 15.7 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase F1F0-ATPsyn_F PF10791.4 KND91466.1 - 1.3e-38 131.0 0.1 1.6e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF2771 PF10969.3 KND91466.1 - 0.0071 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2771) MOZ_SAS PF01853.13 KND91468.1 - 2e-85 284.7 0.3 2.9e-85 284.2 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KND91468.1 - 1.6e-17 62.9 0.0 8.6e-17 60.5 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF2314 PF10077.4 KND91468.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Acetyltransf_7 PF13508.1 KND91468.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND91468.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1237 PF06824.6 KND91469.1 - 1.9e-178 593.4 0.0 2.2e-178 593.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Aminotran_1_2 PF00155.16 KND91470.1 - 1.1e-25 90.4 0.0 1.4e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CDC27 PF09507.5 KND91471.1 - 1.9e-82 277.8 24.1 2.8e-82 277.2 16.7 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 CDC45 PF02724.9 KND91471.1 - 3.5 5.5 9.7 5.1 4.9 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein MCM PF00493.18 KND91472.1 - 1.8e-136 454.3 0.9 1.8e-136 454.3 0.6 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KND91472.1 - 4.6e-21 75.5 0.4 1.5e-20 73.9 0.0 2.1 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND91472.1 - 3.4e-07 29.6 0.0 9.4e-07 28.2 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2360 PF10152.4 KND91472.1 - 0.00043 20.5 0.0 0.027 14.7 0.0 3.2 3 1 0 3 3 3 1 Predicted coiled-coil domain-containing protein (DUF2360) Sigma54_activat PF00158.21 KND91472.1 - 0.0014 18.0 0.0 0.0036 16.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KND91472.1 - 0.0021 17.6 0.4 0.0051 16.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND91472.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNase_T PF00929.19 KND91474.1 - 1.6e-19 70.8 0.0 2.8e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease CMAS PF02353.15 KND91475.1 - 2.6e-70 236.6 0.0 4.5e-70 235.8 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KND91475.1 - 9.6e-12 44.9 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91475.1 - 7.4e-10 39.1 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91475.1 - 3.2e-09 37.3 0.0 5.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND91475.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND91475.1 - 8.9e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND91475.1 - 0.00012 22.4 0.0 0.00023 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND91475.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 KND91475.1 - 0.018 14.5 0.0 0.14 11.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_3 PF01596.12 KND91475.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 KND91475.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GARS_A PF01071.14 KND91476.1 - 9.5e-83 276.5 0.0 1.5e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KND91476.1 - 9.2e-38 128.7 0.2 1.3e-36 125.0 0.0 2.8 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KND91476.1 - 7.1e-32 110.5 0.0 1.5e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KND91476.1 - 1.1e-21 76.8 0.1 4.3e-21 74.8 0.0 2.2 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KND91476.1 - 3.9e-17 62.2 1.6 1.2e-16 60.6 0.3 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KND91476.1 - 2e-09 37.4 0.0 4.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KND91476.1 - 3.9e-08 32.4 0.0 4.6e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 KND91476.1 - 0.00013 21.3 0.1 0.00025 20.4 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 KND91476.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KND91476.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KND91476.1 - 0.0035 17.2 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KND91476.1 - 0.025 14.0 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain TRAPP PF04051.11 KND91477.1 - 4.1e-38 130.2 0.0 5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Nucleoporin_FG PF13634.1 KND91478.1 - 2.2e-32 111.6 170.4 7.6e-14 51.9 38.2 4.1 2 1 3 5 5 5 4 Nucleoporin FG repeat region DUF3584 PF12128.3 KND91478.1 - 0.0038 14.6 1.2 0.022 12.1 0.2 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) DUF4455 PF14643.1 KND91478.1 - 0.011 14.3 0.5 0.91 8.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Fzo_mitofusin PF04799.8 KND91478.1 - 0.061 12.6 0.1 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 fzo-like conserved region HrpB7 PF09486.5 KND91478.1 - 0.086 12.7 2.2 0.19 11.6 1.5 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Hemerythrin PF01814.18 KND91478.1 - 0.19 11.9 0.3 0.66 10.1 0.1 1.9 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Med15 PF09606.5 KND91478.1 - 8.9 4.3 42.5 11 4.0 29.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Fip1 PF05182.8 KND91479.1 - 1.9e-20 71.8 1.1 3.5e-20 70.9 0.7 1.4 1 0 0 1 1 1 1 Fip1 motif F-box-like PF12937.2 KND91480.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like Glyco_hydro_18 PF00704.23 KND91481.1 - 1.4e-12 47.7 3.8 3.1e-12 46.6 2.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 2-oxoacid_dh PF00198.18 KND91482.1 - 1e-76 257.2 0.3 1.3e-76 256.9 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KND91482.1 - 9.8e-20 69.9 1.1 2.5e-19 68.6 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KND91482.1 - 1.4e-14 53.4 0.5 3.3e-14 52.2 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain S4_2 PF13275.1 KND91482.1 - 0.019 14.5 0.2 1.5 8.4 0.0 2.8 2 0 0 2 2 2 0 S4 domain DUF3614 PF12267.3 KND91482.1 - 0.025 14.8 3.1 0.032 14.4 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.1 KND91482.1 - 0.059 13.0 1.0 0.58 9.8 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like Sec7 PF01369.15 KND91483.1 - 1e-61 207.9 3.5 2.3e-61 206.7 0.2 2.9 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 KND91483.1 - 4.2e-37 127.1 8.7 2.3e-19 69.4 0.1 4.2 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KND91483.1 - 1.7e-32 110.7 0.5 6.3e-31 105.7 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) M20_dimer PF07687.9 KND91484.1 - 0.086 12.5 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Peptidase dimerisation domain HEAT_EZ PF13513.1 KND91484.1 - 7.7 7.1 9.2 9.2 6.8 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat RNA_pol_3_Rpc31 PF11705.3 KND91485.1 - 1.6e-34 119.8 0.6 1.9e-34 119.6 0.4 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PBD PF00786.23 KND91486.1 - 0.002 18.5 0.0 0.011 16.1 0.0 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Mg_trans_NIPA PF05653.9 KND91487.1 - 2.8e-60 203.8 10.9 1.4e-57 194.9 4.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KND91487.1 - 0.0002 21.5 0.5 0.0002 21.5 0.4 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter LRR19-TM PF15176.1 KND91487.1 - 0.081 12.6 0.0 0.34 10.6 0.0 2.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain YfhO PF09586.5 KND91487.1 - 0.084 10.8 5.2 0.13 10.2 3.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO EamA PF00892.15 KND91487.1 - 0.28 11.2 30.3 0.025 14.6 1.9 4.2 3 1 1 4 4 4 0 EamA-like transporter family DUF4131 PF13567.1 KND91487.1 - 0.58 9.5 10.9 0.62 9.4 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF1772 PF08592.6 KND91487.1 - 0.64 9.7 11.3 1 9.1 0.7 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF2101 PF09874.4 KND91487.1 - 1.7 8.1 5.8 2 7.8 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Cnd3 PF12719.2 KND91488.1 - 4.9e-87 291.6 1.1 2.9e-86 289.1 0.1 2.6 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KND91488.1 - 1e-07 32.1 11.7 0.00041 20.5 0.2 5.5 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KND91488.1 - 0.0011 18.9 12.5 0.15 12.2 0.0 6.6 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 KND91488.1 - 4.1 8.0 15.3 3.3 8.2 0.0 6.7 4 1 3 7 7 7 0 HEAT-like repeat Phosphodiest PF01663.17 KND91489.1 - 1.5e-10 41.0 0.3 4.9e-09 35.9 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KND91489.1 - 0.03 13.6 0.0 0.058 12.7 0.0 1.4 1 1 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.18 KND91489.1 - 0.048 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Sulfatase DUF896 PF05979.7 KND91490.1 - 0.036 13.6 0.4 0.071 12.7 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DJ-1_PfpI_N PF13587.1 KND91490.1 - 0.11 12.0 0.6 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of DJ-1_PfpI family HTH_CodY PF08222.6 KND91490.1 - 0.13 11.6 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 CodY helix-turn-helix domain RRM_1 PF00076.17 KND91491.1 - 5.2e-57 189.3 0.2 8.7e-16 57.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND91491.1 - 2.9e-46 155.3 0.1 5.2e-15 55.1 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND91491.1 - 7.1e-21 73.8 0.3 1.8e-06 27.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 KND91493.1 - 0.00045 19.9 0.0 0.0007 19.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND91493.1 - 0.0076 16.5 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91493.1 - 0.008 16.7 0.1 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91493.1 - 0.08 13.4 0.1 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF2917 PF11142.3 KND91493.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) DUF2423 PF10338.4 KND91494.1 - 1.1e-14 54.1 6.7 1.1e-14 54.1 4.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Phage_int_SAM_5 PF13102.1 KND91494.1 - 0.03 14.2 0.7 0.038 13.9 0.5 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain PINIT PF14324.1 KND91495.1 - 2e-33 115.4 0.1 4.5e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KND91495.1 - 1.3e-21 75.8 5.5 2.5e-21 74.9 3.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KND91495.1 - 1.3e-05 24.6 1.1 2.7e-05 23.5 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KND91495.1 - 0.0001 21.6 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.10 KND91495.1 - 0.015 14.8 1.6 0.029 13.9 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PBP1_TM PF14812.1 KND91495.1 - 0.047 13.9 1.0 8 6.8 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC4_4 PF15227.1 KND91495.1 - 0.12 12.2 5.2 0.27 11.1 3.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KND91495.1 - 0.36 10.6 2.9 0.69 9.6 2.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3246 PF11596.3 KND91495.1 - 6.6 5.9 16.1 2.5 7.3 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3246) NDUF_B4 PF07225.7 KND91496.1 - 0.0041 16.9 0.1 0.0046 16.7 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Prp18 PF02840.10 KND91497.1 - 7.4e-50 168.5 0.0 7.4e-50 168.5 0.0 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KND91497.1 - 4.2e-10 38.7 0.1 4.2e-10 38.7 0.1 2.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Borrelia_P83 PF05262.6 KND91497.1 - 0.43 8.7 8.6 0.49 8.5 6.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Hemerythrin PF01814.18 KND91498.1 - 0.00028 21.0 0.6 0.00028 21.0 0.4 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain COPI_C PF06957.6 KND91498.1 - 0.22 10.0 0.5 0.28 9.6 0.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus RPN7 PF10602.4 KND91499.1 - 3.8e-49 166.4 0.0 6.1e-49 165.7 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KND91499.1 - 4.1e-12 46.3 0.0 1.2e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KND91499.1 - 0.059 13.3 0.2 29 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KND91500.1 - 1.3e-27 96.3 0.0 1.9e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91500.1 - 8.1e-11 41.6 13.6 1.5e-10 40.7 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.19 KND91501.1 - 6.1e-59 199.0 0.2 8.5e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KND91501.1 - 1.4e-22 79.5 0.0 3.5e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Lectin_leg-like PF03388.8 KND91502.1 - 1.1e-27 96.6 0.0 1.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family FUSC PF04632.7 KND91502.1 - 0.00022 19.8 2.4 0.00031 19.3 1.7 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family AATF-Che1 PF13339.1 KND91502.1 - 0.0039 17.3 2.3 0.0071 16.4 1.6 1.4 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor Taxilin PF09728.4 KND91502.1 - 0.018 14.1 2.4 0.028 13.5 1.7 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF2408 PF10303.4 KND91502.1 - 0.024 14.7 1.3 0.038 14.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Mnd1 PF03962.10 KND91502.1 - 0.046 13.3 2.3 0.073 12.7 1.6 1.2 1 0 0 1 1 1 0 Mnd1 family Baculo_PEP_C PF04513.7 KND91502.1 - 0.064 13.0 2.7 0.21 11.4 0.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 KND91502.1 - 0.071 12.5 3.9 0.12 11.7 2.7 1.4 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 KND91502.1 - 0.079 11.6 4.3 0.14 10.7 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 KND91502.1 - 0.088 13.2 3.4 0.29 11.5 2.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 KND91502.1 - 0.092 12.8 3.1 0.18 11.8 2.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0184 PF03670.8 KND91502.1 - 0.099 12.8 1.4 0.2 11.8 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Occludin_ELL PF07303.8 KND91502.1 - 0.11 13.1 4.7 0.74 10.5 3.0 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF1631 PF07793.6 KND91502.1 - 0.14 10.2 7.2 0.19 9.8 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Laminin_II PF06009.7 KND91502.1 - 0.17 11.6 2.0 0.28 10.9 1.4 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF342 PF03961.8 KND91502.1 - 0.2 10.0 0.8 0.29 9.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 KND91502.1 - 0.23 11.3 2.8 0.4 10.5 1.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 KND91502.1 - 0.23 10.5 3.5 0.36 9.8 2.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein EzrA PF06160.7 KND91502.1 - 0.24 9.5 4.2 0.35 9.0 2.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.6 KND91502.1 - 0.26 11.1 1.3 0.72 9.7 0.9 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 KND91502.1 - 0.3 10.8 5.6 9 6.1 0.3 2.8 1 1 1 2 2 2 0 Prefoldin subunit Rabaptin PF03528.10 KND91502.1 - 0.39 10.6 4.4 0.66 9.9 3.1 1.3 1 0 0 1 1 1 0 Rabaptin Syntaxin_2 PF14523.1 KND91502.1 - 1.1 9.3 6.8 1.1 9.2 1.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Striatin PF08232.7 KND91502.1 - 1.1 9.5 6.1 0.59 10.4 0.9 2.1 1 1 1 2 2 2 0 Striatin family DUF1515 PF07439.6 KND91502.1 - 1.2 8.9 3.0 2.9 7.7 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) FlxA PF14282.1 KND91502.1 - 1.7 8.6 13.3 0.043 13.7 4.8 1.6 2 0 0 2 2 1 0 FlxA-like protein Alg6_Alg8 PF03155.10 KND91503.1 - 7.8e-140 466.8 31.1 1e-139 466.4 21.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DDT PF02791.12 KND91504.1 - 3.8e-17 61.7 0.9 6.2e-17 61.1 0.7 1.3 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KND91504.1 - 6.5e-14 51.2 0.3 1.3e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WAC_Acf1_DNA_bd PF10537.4 KND91504.1 - 1e-12 48.1 2.8 1.8e-12 47.3 0.0 2.8 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM1 PF15612.1 KND91504.1 - 1.1e-05 25.0 0.1 4.4e-05 23.2 0.1 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KND91504.1 - 0.0011 18.6 0.5 0.0037 17.0 0.3 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 PROCN PF08083.6 KND91505.1 - 5.6e-222 736.5 6.3 9e-222 735.8 4.4 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KND91505.1 - 8.8e-125 414.5 1.3 1.7e-124 413.6 0.9 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KND91505.1 - 9.5e-94 311.0 1.5 2.1e-93 309.9 1.0 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KND91505.1 - 1.9e-75 251.6 4.6 3.8e-75 250.6 2.2 2.3 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KND91505.1 - 7.4e-66 219.8 0.1 1.5e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KND91505.1 - 2.5e-42 143.5 0.7 5e-42 142.5 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 KND91505.1 - 6.7e-42 141.2 0.0 1.7e-41 139.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 OCD_Mu_crystall PF02423.10 KND91505.1 - 0.096 11.4 0.9 0.18 10.5 0.6 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SAP18 PF06487.7 KND91506.1 - 2.2e-31 108.1 0.0 2.8e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1469 PF07332.6 KND91507.1 - 0.001 18.8 3.7 0.001 18.8 2.6 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1469) DUF4131 PF13567.1 KND91507.1 - 0.89 8.9 12.6 3.1 7.1 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) TMEM154 PF15102.1 KND91508.1 - 0.089 12.4 0.0 0.38 10.4 0.0 2.0 1 0 0 1 1 1 0 TMEM154 protein family Ctr PF04145.10 KND91508.1 - 0.72 9.8 0.0 0.72 9.8 0.0 2.6 2 1 0 2 2 2 0 Ctr copper transporter family Pkinase PF00069.20 KND91509.1 - 1.9e-55 187.8 0.0 3.1e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91509.1 - 1.1e-19 70.5 0.5 1.7e-19 69.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND91509.1 - 0.044 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND91509.1 - 0.27 10.7 0.3 0.52 9.8 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HhH-GPD PF00730.20 KND91511.1 - 6.1e-17 61.8 0.0 3.4e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Recep_L_domain PF01030.19 KND91512.1 - 0.054 13.4 12.7 0.079 12.9 0.5 4.2 1 1 3 4 4 4 0 Receptor L domain DUF1118 PF06549.7 KND91512.1 - 0.21 11.7 2.3 2.1 8.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Snf7 PF03357.16 KND91513.1 - 8.5e-31 106.6 21.0 8.5e-31 106.6 14.6 2.0 1 1 1 2 2 2 1 Snf7 DUF2937 PF11157.3 KND91513.1 - 0.069 12.4 5.7 0.12 11.6 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Bcr-Abl_Oligo PF09036.5 KND91513.1 - 0.088 12.7 0.4 0.27 11.2 0.2 1.9 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain FMN_bind PF04205.9 KND91513.1 - 0.099 12.8 2.7 0.19 11.9 1.1 2.0 1 1 0 1 1 1 0 FMN-binding domain DUF885 PF05960.6 KND91513.1 - 0.3 10.1 10.6 0.36 9.9 7.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF1216 PF06746.6 KND91513.1 - 0.7 9.6 7.3 0.31 10.8 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Allexi_40kDa PF05549.6 KND91513.1 - 1.3 8.2 7.8 1.8 7.8 5.0 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein MutS_III PF05192.13 KND91513.1 - 2.6 7.7 10.1 7.1 6.3 7.0 1.7 1 1 0 1 1 1 0 MutS domain III Anp1 PF03452.9 KND91514.1 - 3.9e-108 360.6 0.1 4.9e-108 360.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 G-patch PF01585.18 KND91515.1 - 1.9e-12 46.7 0.0 1.9e-12 46.7 0.0 2.5 3 0 0 3 3 3 1 G-patch domain RRM_5 PF13893.1 KND91515.1 - 2e-06 27.5 0.6 5.1e-06 26.2 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND91515.1 - 0.00058 19.4 0.1 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND91515.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 KND91516.1 - 2.2e-32 111.8 0.0 6.3e-32 110.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND91516.1 - 1.3e-22 79.4 0.1 2.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KND91516.1 - 3.4e-05 23.4 0.7 0.0055 16.4 0.0 3.0 2 1 1 3 3 3 1 Part of AAA domain Helicase_C_2 PF13307.1 KND91516.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 KND91516.1 - 0.017 14.9 0.0 0.074 12.8 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND91516.1 - 0.11 12.6 0.2 1.1 9.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KND91517.1 - 6.2e-05 22.8 11.3 0.00011 22.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRR1 PF07985.7 KND91517.1 - 0.0098 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 SRR1 Mem_trans PF03547.13 KND91517.1 - 0.27 9.4 0.1 0.25 9.6 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein SMN PF06003.7 KND91517.1 - 0.3 10.1 8.3 0.55 9.3 5.8 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ycf1 PF05758.7 KND91517.1 - 0.61 7.7 12.7 0.79 7.3 8.8 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 KND91517.1 - 0.64 7.6 16.9 0.85 7.2 11.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.5 KND91517.1 - 1 7.4 60.4 1.5 6.9 41.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 KND91517.1 - 1 8.4 6.8 1.4 8.0 4.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NARP1 PF12569.3 KND91517.1 - 1.1 7.9 17.6 1.5 7.4 12.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_11 PF13086.1 KND91517.1 - 1.4 8.4 18.5 2.2 7.8 12.8 1.2 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 KND91517.1 - 2.5 6.8 15.7 3.5 6.3 10.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PIH1 PF08190.7 KND91517.1 - 2.7 7.3 26.1 4.1 6.7 18.1 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 AUX_IAA PF02309.11 KND91517.1 - 3.4 7.3 16.4 5.7 6.6 11.4 1.3 1 0 0 1 1 1 0 AUX/IAA family BORG_CEP PF14957.1 KND91517.1 - 3.6 8.5 12.3 10 7.0 8.5 1.8 1 0 0 1 1 1 0 Cdc42 effector CDK5_activator PF03261.10 KND91517.1 - 3.7 6.7 18.1 5.4 6.2 12.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Tim54 PF11711.3 KND91517.1 - 4.6 5.7 13.9 6.6 5.2 9.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.8 KND91517.1 - 5 5.7 19.6 9.3 4.8 13.6 1.4 1 0 0 1 1 1 0 Paf1 DUF4407 PF14362.1 KND91517.1 - 5.3 5.9 18.4 8.5 5.2 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AvrE PF11725.3 KND91517.1 - 5.6 3.8 19.8 7.3 3.4 13.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor eIF-3_zeta PF05091.7 KND91517.1 - 5.7 5.4 23.9 8.1 4.9 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FimP PF09766.4 KND91517.1 - 6 5.8 28.9 10 5.0 20.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein Baculo_PP31 PF05311.6 KND91517.1 - 6.5 5.9 18.0 10 5.2 12.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Zip PF02535.17 KND91517.1 - 6.9 5.5 11.6 9.5 5.1 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.8 KND91517.1 - 8.7 6.1 35.5 0.77 9.5 21.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.1 KND91517.1 - 8.9 6.4 17.1 16 5.6 11.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.9 KND91517.1 - 9 4.1 15.8 12 3.8 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 KND91517.1 - 9.6 5.6 17.9 16 4.8 12.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CLN3 PF02487.12 KND91519.1 - 3.7e-107 358.6 9.6 2.4e-104 349.3 6.7 2.2 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 KND91519.1 - 1.8e-05 23.6 23.6 3.1e-05 22.8 5.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KND91520.1 - 9.1e-14 50.9 18.2 1.1e-13 50.6 12.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND91520.1 - 5.7e-06 25.1 5.8 8.8e-06 24.5 4.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_transf_34 PF05637.7 KND91521.1 - 2.9e-07 30.2 1.3 3.1e-06 26.8 0.9 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KND91521.1 - 1.1e-05 25.3 0.1 3.2e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.9 KND91521.1 - 0.093 12.0 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF273 TMEM171 PF15471.1 KND91521.1 - 0.22 10.2 0.2 0.35 9.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Col_cuticle_N PF01484.12 KND91521.1 - 1.6 8.4 5.3 16 5.2 0.2 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Rxt3 PF08642.5 KND91522.1 - 1e-25 90.1 0.0 2.9e-25 88.7 0.0 1.8 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KND91522.1 - 0.00011 22.0 0.0 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 1 LCCL domain FPN1 PF06963.7 KND91523.1 - 1.3e-116 389.5 12.0 1.7e-116 389.1 8.3 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CTP_transf_2 PF01467.21 KND91524.1 - 1.8e-07 31.3 0.0 4.1e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 KND91524.1 - 0.0044 16.6 0.0 0.0065 16.1 0.0 1.1 1 0 0 1 1 1 1 FAD synthetase DUF1674 PF07896.7 KND91525.1 - 5.8e-17 61.6 2.3 7.5e-17 61.2 1.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Chitin_synth_1 PF01644.12 KND91526.1 - 1.2e-69 233.2 0.0 1.9e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KND91526.1 - 1e-26 93.4 0.1 5.9e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KND91526.1 - 1.3e-26 92.0 0.1 2.6e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KND91526.1 - 2.3e-09 37.2 8.4 3.5e-08 33.3 5.8 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND91526.1 - 9.6e-08 32.1 0.0 2.9e-07 30.5 0.0 1.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Opy2 PF09463.5 KND91527.1 - 2e-05 24.5 17.6 3.4e-05 23.8 12.2 1.4 1 0 0 1 1 1 1 Opy2 protein DUF1517 PF07466.6 KND91527.1 - 1.5 7.7 4.5 0.45 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Ras PF00071.17 KND91528.1 - 2.4e-51 173.3 0.0 4.6e-51 172.4 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KND91528.1 - 8.7e-17 61.7 0.0 4.5e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KND91528.1 - 0.0011 18.2 0.0 0.0029 16.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND91528.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Abhydrolase_4 PF08386.5 KND91528.1 - 0.027 14.3 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein FeoB_N PF02421.13 KND91528.1 - 0.03 13.6 0.1 0.24 10.6 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 KND91528.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 KND91529.1 - 2.4e-26 93.0 0.2 1.2e-25 90.7 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND91529.1 - 6.2e-09 36.5 0.0 1.4e-08 35.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND91529.1 - 1.8e-06 27.5 0.0 4.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like CbiJ PF02571.9 KND91529.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Rep_fac-A_C PF08646.5 KND91530.1 - 1.8e-09 37.4 0.1 1.9e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain Aldedh PF00171.17 KND91531.1 - 5.8e-10 38.0 1.3 4.7e-05 21.9 0.3 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Tbf5 PF06331.7 KND91531.1 - 0.021 14.5 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 PALP PF00291.20 KND91532.1 - 6.6e-65 219.3 4.2 8.9e-65 218.9 2.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UQ_con PF00179.21 KND91533.1 - 1.4e-35 121.7 0.0 2e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_MLP1_2 PF07926.7 KND91534.1 - 0.0056 16.4 17.4 0.037 13.7 8.6 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KND91534.1 - 0.031 12.0 16.4 0.02 12.6 9.8 1.6 1 1 0 1 1 1 0 Myosin tail DivIC PF04977.10 KND91534.1 - 0.048 13.1 0.4 0.048 13.1 0.3 2.2 1 1 2 3 3 3 0 Septum formation initiator IncA PF04156.9 KND91534.1 - 0.081 12.5 18.8 0.78 9.2 6.6 2.2 1 1 1 2 2 2 0 IncA protein Transposase_22 PF02994.9 KND91534.1 - 0.086 11.3 5.5 0.13 10.6 3.8 1.2 1 0 0 1 1 1 0 L1 transposable element Seryl_tRNA_N PF02403.17 KND91534.1 - 0.59 10.1 6.2 0.87 9.6 3.8 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KND91534.1 - 1.1 7.8 9.3 1.8 7.1 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup54 PF13874.1 KND91534.1 - 2.9 7.5 8.5 5.8 6.5 5.9 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 AAA_13 PF13166.1 KND91534.1 - 3.8 5.8 9.3 7.9 4.7 6.5 1.3 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 KND91534.1 - 4.1 7.3 18.9 5.9 6.7 5.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 KND91534.1 - 9.8 5.6 8.4 32 4.0 5.8 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPMT PF05724.6 KND91535.1 - 9.1e-28 97.1 0.0 5.2e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KND91535.1 - 6.6e-07 29.8 0.1 1.7e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND91535.1 - 1.3e-06 28.1 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND91535.1 - 2.2e-05 24.7 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND91535.1 - 5.8e-05 23.1 1.0 0.00012 22.1 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND91535.1 - 9.7e-05 21.9 0.0 0.00075 19.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KND91535.1 - 0.0058 15.8 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ank_2 PF12796.2 KND91537.1 - 1.2e-16 60.7 0.0 4.6e-13 49.3 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND91537.1 - 6.8e-16 57.2 0.8 1.4e-07 30.9 0.1 5.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KND91537.1 - 2.4e-13 50.2 0.3 2.5e-08 34.1 0.0 4.5 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND91537.1 - 1.3e-12 46.6 0.0 0.00015 21.6 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KND91537.1 - 2.7e-08 33.7 0.4 0.00011 22.3 0.1 4.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Lsm_interact PF05391.6 KND91538.1 - 0.99 8.9 7.7 0.14 11.6 1.4 2.4 2 0 0 2 2 2 0 Lsm interaction motif Sugar_tr PF00083.19 KND91540.1 - 1.4e-72 244.7 30.9 1.6e-72 244.5 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91540.1 - 3.4e-12 45.7 53.1 4.3e-11 42.1 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND91540.1 - 0.0001 20.8 30.5 0.001 17.5 2.6 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein DUF384 PF04064.8 KND91541.1 - 0.06 12.9 0.1 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Inositol_P PF00459.20 KND91543.1 - 5e-40 137.5 0.0 1e-39 136.5 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Mob1_phocein PF03637.12 KND91544.1 - 6.8e-33 113.7 0.6 1.8e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family ABC_tran PF00005.22 KND91546.1 - 1.2e-47 161.6 0.1 6.2e-24 84.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND91546.1 - 2.2e-17 63.9 0.0 0.00073 19.5 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KND91546.1 - 2.6e-15 56.2 0.1 3.9e-05 23.0 0.1 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND91546.1 - 4.3e-10 38.9 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KND91546.1 - 4.5e-08 32.4 0.0 0.00039 19.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KND91546.1 - 5.8e-08 33.5 0.0 0.0066 17.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KND91546.1 - 9.5e-08 32.2 0.0 0.0032 17.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 KND91546.1 - 3.8e-07 30.0 0.0 0.005 16.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 KND91546.1 - 4e-07 30.1 0.1 0.018 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KND91546.1 - 9.2e-07 29.3 1.1 0.00031 21.1 0.3 3.2 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.1 KND91546.1 - 2.4e-06 27.4 0.3 0.14 11.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain Dynamin_N PF00350.18 KND91546.1 - 5.2e-06 26.3 0.0 0.0013 18.6 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 KND91546.1 - 5.2e-06 26.1 0.0 0.21 10.9 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 KND91546.1 - 7.6e-06 26.4 0.0 0.033 14.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 KND91546.1 - 7.9e-06 25.7 0.0 0.039 13.8 0.0 3.4 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KND91546.1 - 1.1e-05 25.5 0.7 0.83 9.6 0.0 4.6 5 0 0 5 5 5 1 AAA ATPase domain ArgK PF03308.11 KND91546.1 - 1.1e-05 24.3 0.1 0.11 11.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_18 PF13238.1 KND91546.1 - 1.4e-05 25.3 2.5 0.14 12.4 0.1 4.1 4 0 0 4 4 2 2 AAA domain AAA PF00004.24 KND91546.1 - 1.9e-05 24.8 0.0 0.41 10.8 0.0 4.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KND91546.1 - 2.1e-05 24.2 0.0 0.31 10.7 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KND91546.1 - 3e-05 23.2 9.9 0.11 11.4 0.0 5.4 5 1 1 6 6 6 1 AAA ATPase domain PduV-EutP PF10662.4 KND91546.1 - 3.5e-05 23.3 0.1 0.11 11.9 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KND91546.1 - 5.8e-05 23.2 0.0 0.77 9.9 0.0 3.2 2 0 0 2 2 2 2 RNA helicase AAA_13 PF13166.1 KND91546.1 - 6.5e-05 21.5 0.5 1.4 7.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain NACHT PF05729.7 KND91546.1 - 0.00011 21.9 0.0 0.056 13.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KND91546.1 - 0.00026 20.7 0.0 1.3 8.6 0.0 3.1 2 0 0 2 2 2 2 Archaeal ATPase HEAT PF02985.17 KND91546.1 - 0.00031 20.5 0.4 1.2 9.4 0.1 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KND91546.1 - 0.00038 20.6 3.5 1.1 9.5 2.6 3.0 1 1 0 2 2 2 1 HEAT repeats AAA_14 PF13173.1 KND91546.1 - 0.00039 20.3 0.0 1.8 8.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 KND91546.1 - 0.0008 18.8 0.6 1.6 8.1 0.0 3.6 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KND91546.1 - 0.00091 18.3 0.5 0.78 8.7 0.0 3.3 3 0 0 3 3 3 1 Septin DUF87 PF01935.12 KND91546.1 - 0.0035 17.1 2.2 0.95 9.2 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_30 PF13604.1 KND91546.1 - 0.0036 16.9 0.0 6 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KND91546.1 - 0.0036 16.8 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 KND91546.1 - 0.0049 16.4 0.0 6.5 6.2 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KND91546.1 - 0.007 15.7 0.0 6.7 6.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain MutS_V PF00488.16 KND91546.1 - 0.0072 15.7 0.1 0.75 9.1 0.0 2.5 2 0 0 2 2 2 1 MutS domain V G-alpha PF00503.15 KND91546.1 - 0.02 13.6 0.1 1.5 7.4 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit Cnd1 PF12717.2 KND91546.1 - 0.021 14.6 0.0 0.24 11.2 0.0 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 T2SE PF00437.15 KND91546.1 - 0.022 13.6 0.2 2.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ParcG PF10274.4 KND91546.1 - 0.028 14.3 0.3 0.55 10.0 0.0 2.7 1 1 2 3 3 3 0 Parkin co-regulated protein FtsK_SpoIIIE PF01580.13 KND91546.1 - 0.035 13.5 0.1 5.5 6.4 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 KND91546.1 - 0.042 13.4 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 KND91546.1 - 0.061 12.4 0.0 3.8 6.6 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Plasmid_Txe PF06769.8 KND91546.1 - 0.099 12.4 0.9 0.72 9.7 0.2 2.3 2 0 0 2 2 2 0 Plasmid encoded toxin Txe RNase_H2_suC PF08615.6 KND91547.1 - 2e-23 82.7 0.0 2.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TPR_11 PF13414.1 KND91548.1 - 1.7e-17 62.7 8.2 8.4e-12 44.5 0.1 5.3 5 0 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 KND91548.1 - 1.3e-11 43.5 13.1 0.00013 21.5 0.0 5.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND91548.1 - 1.7e-11 43.1 6.2 0.0023 17.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND91548.1 - 6.8e-09 36.1 11.2 4.4e-08 33.5 0.0 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND91548.1 - 1.2e-07 31.6 0.5 8.2e-05 22.4 0.3 5.2 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KND91548.1 - 1.5e-06 27.5 10.7 0.019 14.7 0.0 4.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KND91548.1 - 6.6e-06 26.3 2.3 0.042 14.1 0.0 4.2 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND91548.1 - 7.4e-05 23.0 21.0 0.016 15.8 0.0 6.4 6 1 1 7 7 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KND91548.1 - 0.00014 21.8 0.4 0.023 14.7 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KND91548.1 - 0.0014 18.4 2.0 0.0082 15.9 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KND91548.1 - 0.0017 18.0 7.4 0.22 11.4 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.1 KND91548.1 - 0.0032 16.6 2.6 0.086 11.9 0.2 2.5 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.4 KND91548.1 - 0.058 12.7 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Coatomer_WDAD PF04053.9 KND91548.1 - 0.063 12.0 0.1 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region TPR_6 PF13174.1 KND91548.1 - 0.074 13.5 5.7 29 5.4 0.2 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KND91548.1 - 0.082 12.1 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 SHNi-TPR AA_permease PF00324.16 KND91549.1 - 1.9e-90 303.5 32.3 2.4e-90 303.2 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND91549.1 - 7e-28 97.3 35.6 8.8e-28 96.9 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease GYF PF02213.11 KND91550.1 - 3.9e-19 67.9 0.1 1.2e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 GYF domain Acyltransferase PF01553.16 KND91552.1 - 5.1e-18 64.7 0.0 1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 KND91553.1 - 1.1e-23 82.7 0.0 1.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Aldedh PF00171.17 KND91554.1 - 1e-178 594.4 6.8 2.9e-178 592.9 4.7 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF4298 PF14131.1 KND91554.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Pantoate_ligase PF02569.10 KND91555.1 - 3.7e-63 212.9 0.0 3.2e-31 108.1 0.0 2.4 1 1 1 2 2 2 2 Pantoate-beta-alanine ligase MFS_1 PF07690.11 KND91555.1 - 4.3e-35 121.0 52.5 4.3e-35 121.0 36.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3377 PF11857.3 KND91555.1 - 0.11 12.1 0.0 0.39 10.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RhodobacterPufX PF11511.3 KND91555.1 - 0.4 10.1 3.2 3 7.2 0.2 3.4 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Alpha_kinase PF02816.13 KND91556.1 - 1.2e-45 155.5 0.0 1.8e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 KND91556.1 - 2.8e-06 27.5 0.0 6.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KND91556.1 - 0.00035 20.3 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain p450 PF00067.17 KND91557.1 - 2.2e-72 244.0 0.0 2.8e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 KND91558.1 - 4.3e-39 134.2 0.0 3.6e-21 75.3 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KND91558.1 - 5.9e-29 101.1 0.0 1.1e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3505 PF12013.3 KND91559.1 - 3.2e-13 49.8 0.9 1.5e-12 47.6 0.3 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3505) BIR PF00653.16 KND91559.1 - 0.0034 17.7 0.3 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-BED PF02892.10 KND91559.1 - 0.0049 16.5 4.7 0.99 9.2 0.0 2.5 2 0 0 2 2 2 2 BED zinc finger zf-H2C2_5 PF13909.1 KND91559.1 - 0.0074 16.4 1.6 0.0074 16.4 1.1 2.2 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KND91559.1 - 0.017 15.4 9.3 0.24 11.8 1.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.7 KND91559.1 - 0.038 13.7 0.1 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KND91559.1 - 0.04 14.0 2.0 1.8 8.6 1.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KND91559.1 - 2.3 8.7 6.7 2.2 8.7 1.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ank_2 PF12796.2 KND91560.1 - 7.3e-24 83.9 29.3 0.0061 16.8 0.1 11.9 4 4 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KND91560.1 - 1.4e-09 37.2 19.1 1.2 9.5 0.0 14.6 17 0 0 17 17 17 2 Ankyrin repeat Ank PF00023.25 KND91560.1 - 1.8e-07 30.6 29.7 22 5.1 0.0 14.8 18 0 0 18 18 18 3 Ankyrin repeat Ank_5 PF13857.1 KND91560.1 - 4.7e-05 23.4 5.8 5.6 7.3 0.0 8.1 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND91560.1 - 0.0026 18.2 20.3 3.4 8.3 0.0 10.2 11 3 1 12 12 12 2 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.16 KND91563.1 - 1.3e-26 93.4 0.0 3e-26 92.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND91563.1 - 0.018 13.3 0.0 0.12 10.6 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.8 KND91564.1 - 3.7e-28 97.1 0.0 7.9e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KND91564.1 - 3e-14 53.5 0.1 4.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily F-box PF00646.28 KND91566.1 - 0.012 15.2 0.0 0.083 12.5 0.1 2.3 2 0 0 2 2 2 0 F-box domain TFIIIC_sub6 PF10419.4 KND91567.1 - 1.4e-12 46.8 0.0 2.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit Daxx PF03344.10 KND91567.1 - 1.5 7.2 16.7 0.71 8.2 0.5 2.4 3 0 0 3 3 3 0 Daxx Family DUF946 PF06101.6 KND91568.1 - 1.6e-12 46.1 0.3 3.2e-12 45.2 0.2 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Ribosomal_L16 PF00252.13 KND91571.1 - 4.4e-31 107.4 0.0 6e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 KND91572.1 - 4.1e-25 87.1 0.0 4.7e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HET PF06985.6 KND91573.1 - 0.098 12.8 1.5 0.24 11.5 1.0 1.7 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF3450 PF11932.3 KND91573.1 - 0.16 11.1 16.1 1.7 7.8 7.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HeLo PF14479.1 KND91573.1 - 2.1 8.0 16.2 11 5.7 7.4 2.8 1 1 1 2 2 2 0 Prion-inhibition and propagation ERM PF00769.14 KND91573.1 - 4.9 6.6 35.3 1.4 8.4 15.5 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4200 PF13863.1 KND91573.1 - 6 6.8 43.1 0.2 11.6 0.1 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4200) IncA PF04156.9 KND91573.1 - 9.4 5.7 34.1 0.017 14.7 10.8 3.2 3 0 0 3 3 3 0 IncA protein LMBR1 PF04791.11 KND91573.1 - 9.7 4.6 7.0 13 4.2 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4139 PF13598.1 KND91574.1 - 3.6e-60 203.9 10.5 1.1e-43 149.7 0.3 3.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KND91574.1 - 8.8e-17 61.4 0.4 8.8e-17 61.4 0.3 3.8 4 1 0 4 4 4 1 N-terminal domain of unknown function (DUF4140) DUF1635 PF07795.6 KND91574.1 - 0.092 12.1 0.6 0.18 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Methyltransf_10 PF05971.7 KND91575.1 - 5.1e-62 209.7 0.0 7.2e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KND91575.1 - 4e-06 26.8 0.0 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91575.1 - 5.8e-05 23.6 0.0 0.00024 21.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND91575.1 - 0.00037 19.9 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KND91575.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KND91575.1 - 0.026 15.0 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KND91575.1 - 0.042 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Dehydrin PF00257.14 KND91575.1 - 0.048 13.9 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 Dehydrin DUF633 PF04816.7 KND91575.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) DUF218 PF02698.12 KND91576.1 - 6.7e-31 106.8 0.1 3.9e-30 104.4 0.0 2.2 2 0 0 2 2 2 1 DUF218 domain Arf PF00025.16 KND91576.1 - 1.6e-26 92.6 0.0 2.8e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KND91576.1 - 0.00085 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KND91576.1 - 0.0032 16.7 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KND91576.1 - 0.0053 17.2 0.0 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 KND91576.1 - 0.12 12.2 0.1 8.6 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Iso_dh PF00180.15 KND91578.1 - 1e-115 386.4 0.0 1.2e-115 386.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.8 KND91578.1 - 0.042 13.3 1.1 0.042 13.3 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Cation_ATPase_C PF00689.16 KND91580.1 - 5.6e-16 58.5 0.2 5.6e-16 58.5 0.2 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF1295 PF06966.7 KND91580.1 - 0.033 13.4 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) APH PF01636.18 KND91581.1 - 8.9e-15 55.0 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND91581.1 - 4.4e-07 29.6 0.0 6.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Beta-lactamase PF00144.19 KND91584.1 - 0.0084 15.1 1.9 0.66 8.9 0.3 3.0 2 1 0 2 2 2 2 Beta-lactamase APH PF01636.18 KND91585.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family GATase_5 PF13507.1 KND91586.1 - 1.4e-93 312.5 0.0 2.1e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KND91586.1 - 1e-33 116.5 1.7 4.6e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KND91586.1 - 1.5e-21 76.3 0.2 1.1e-20 73.6 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain HD PF01966.17 KND91587.1 - 1.6e-05 24.8 0.1 3.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 HD domain F-box-like PF12937.2 KND91588.1 - 0.00023 20.8 0.0 0.00069 19.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND91588.1 - 0.00034 20.1 0.1 0.00065 19.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Kp4 PF09044.5 KND91589.1 - 0.039 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Kp4 Esterase_phd PF10503.4 KND91590.1 - 5.4e-07 29.0 0.0 1e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 KND91590.1 - 3.6e-06 26.6 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KND91590.1 - 9.9e-06 25.3 0.0 1.5e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KND91590.1 - 0.0027 17.1 0.0 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KND91590.1 - 0.0059 15.8 0.1 0.025 13.8 0.1 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 KND91590.1 - 0.15 10.5 0.0 2 6.8 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) EF-hand_4 PF12763.2 KND91592.1 - 2.2e-05 24.1 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Myb_DNA-bind_6 PF13921.1 KND91593.1 - 1.1e-14 54.1 0.5 6e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KND91593.1 - 3.4e-11 43.0 0.5 6.1e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.1 KND91593.1 - 0.42 11.4 2.7 0.61 10.9 0.0 2.6 2 1 1 3 3 3 0 Homeodomain-like domain ApbA_C PF08546.6 KND91594.1 - 2.8e-11 43.5 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MFS_1 PF07690.11 KND91596.1 - 1.1e-45 155.8 28.2 1.4e-41 142.4 8.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND91596.1 - 1.2e-10 40.5 10.5 1.2e-10 40.5 7.3 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KND91596.1 - 4.9e-05 21.7 7.7 7.7e-05 21.0 5.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MAP65_ASE1 PF03999.7 KND91597.1 - 5.4e-68 230.1 13.9 1e-67 229.1 9.7 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Sipho_Gp157 PF05565.6 KND91597.1 - 0.069 12.7 3.9 0.23 11.0 0.2 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 LemA PF04011.7 KND91597.1 - 0.1 11.6 0.0 0.25 10.4 0.0 1.6 1 0 0 1 1 1 0 LemA family PNP_UDP_1 PF01048.15 KND91598.1 - 7.2e-05 21.8 0.1 7.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF843 PF05814.6 KND91598.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) p450 PF00067.17 KND91599.1 - 2e-49 168.3 0.0 9.3e-38 129.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pex16 PF08610.5 KND91600.1 - 2.7e-104 348.7 0.0 3.5e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Brr6_like_C_C PF10104.4 KND91601.1 - 3.8e-31 107.4 2.1 7.5e-31 106.4 1.5 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.13 KND91601.1 - 4.8e-22 78.0 0.2 4.8e-22 78.0 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91601.1 - 4.8e-08 32.7 10.8 4.8e-08 32.7 7.5 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 KND91601.1 - 4.1 5.5 6.6 7 4.8 4.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Piwi PF02171.12 KND91602.1 - 3.2e-67 226.6 0.0 4.9e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KND91602.1 - 1.7e-12 46.5 0.1 3.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KND91602.1 - 2.6e-12 46.1 0.0 7.1e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 PAZ domain Methyltransf_29 PF03141.11 KND91602.1 - 0.25 9.6 0.0 1.2 7.3 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-met PF12874.2 KND91603.1 - 0.018 15.2 3.7 0.84 9.9 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KND91603.1 - 0.057 13.7 1.1 0.057 13.7 0.7 3.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND91603.1 - 0.37 11.2 21.0 0.22 11.9 1.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.20 KND91605.1 - 7.9e-41 139.9 0.3 6.2e-25 87.8 0.2 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND91605.1 - 4.3e-14 52.2 0.2 2.5e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.6 KND91606.1 - 2e-12 46.4 0.0 3.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cyto_heme_lyase PF01265.12 KND91608.1 - 1.1e-83 280.8 0.3 1.2e-83 280.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribosomal_L28e PF01778.12 KND91609.1 - 8.3e-41 139.0 2.6 1e-40 138.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Tombus_movement PF05318.7 KND91609.1 - 0.096 13.3 0.7 0.24 12.0 0.5 1.7 1 0 0 1 1 1 0 Tombusvirus movement protein DUF2015 PF09435.5 KND91610.1 - 5.6e-46 155.4 0.0 6.2e-46 155.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ldh_1_N PF00056.18 KND91611.1 - 2.2e-41 140.9 0.2 3e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KND91611.1 - 6.5e-41 139.9 0.0 1e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KND91611.1 - 0.00018 20.3 0.0 0.00025 19.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KND91611.1 - 0.028 14.7 0.0 0.066 13.5 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KND91611.1 - 0.097 11.7 0.2 1.2 8.1 0.1 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_72 PF03198.9 KND91612.1 - 7.1e-123 409.5 3.2 9.5e-123 409.1 2.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KND91612.1 - 7e-07 28.7 0.5 4.4e-06 26.1 0.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aa_trans PF01490.13 KND91614.1 - 8.9e-62 208.8 26.6 1.2e-61 208.4 18.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_UL56 PF04534.7 KND91614.1 - 0.026 14.2 3.5 0.054 13.2 2.4 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein FA_hydroxylase PF04116.8 KND91615.1 - 3.5e-15 56.4 26.9 3.6e-14 53.1 14.4 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.27 KND91616.1 - 3e-70 229.7 15.0 3.8e-10 39.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KND91616.1 - 9.8e-24 83.3 8.5 1.6e-23 82.6 5.9 1.3 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 KND91616.1 - 0.0012 17.6 0.1 0.32 9.7 0.1 3.3 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 KND91616.1 - 0.0057 14.8 0.3 0.31 9.1 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KND91616.1 - 0.011 14.8 0.1 8.2 5.4 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LXG PF04740.7 KND91616.1 - 0.012 15.4 1.9 0.018 14.8 1.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 KND91616.1 - 0.035 11.8 1.8 0.049 11.3 1.3 1.0 1 0 0 1 1 1 0 Myosin tail Cytochrom_D1 PF02239.11 KND91616.1 - 0.048 11.9 0.3 1.1 7.4 0.1 2.6 1 1 1 2 2 2 0 Cytochrome D1 heme domain Tektin PF03148.9 KND91616.1 - 0.059 11.9 2.8 0.082 11.4 2.0 1.1 1 0 0 1 1 1 0 Tektin family Pkinase PF00069.20 KND91617.1 - 6.2e-57 192.7 0.0 9.6e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91617.1 - 1.2e-33 116.3 0.0 1.6e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND91617.1 - 3.9e-14 52.2 0.0 7.5e-13 48.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND91617.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abi PF02517.11 KND91618.1 - 1.7e-13 50.4 8.6 1.7e-13 50.4 6.0 2.3 2 1 1 3 3 3 1 CAAX protease self-immunity DUF1635 PF07795.6 KND91618.1 - 0.051 12.9 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF543 PF04418.7 KND91618.1 - 0.094 12.6 4.9 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Serglycin PF04360.7 KND91618.1 - 1.7 8.3 10.0 2.7 7.7 6.5 1.4 1 1 0 1 1 1 0 Serglycin Synaptobrevin PF00957.16 KND91619.1 - 0.068 12.7 1.0 0.12 11.9 0.7 1.3 1 0 0 1 1 1 0 Synaptobrevin MBOAT PF03062.14 KND91620.1 - 1e-44 153.0 0.1 1e-44 153.0 0.1 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.16 KND91620.1 - 5.8 6.6 12.8 0.2 11.3 3.7 2.2 2 0 0 2 2 2 0 PAP2 superfamily TPT PF03151.11 KND91621.1 - 1.3e-10 41.1 6.2 1.3e-10 41.1 4.3 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KND91621.1 - 4.1e-09 35.7 18.2 5.2e-09 35.4 12.6 1.1 1 0 0 1 1 1 1 UAA transporter family Gti1_Pac2 PF09729.4 KND91622.1 - 1.3e-59 200.8 0.0 1.6e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.16 KND91623.1 - 7.2e-17 61.5 4.7 1.3e-16 60.7 3.3 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 KND91624.1 - 2.1e-154 514.1 0.0 2.9e-154 513.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.18 KND91624.1 - 1.2e-147 492.9 0.0 1.5e-147 492.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family GIDA_assoc_3 PF13932.1 KND91624.1 - 3.5e-14 52.5 0.0 1e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KND91624.1 - 6.9e-07 29.3 0.1 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND91624.1 - 2.7e-06 26.7 0.3 4.3e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND91624.1 - 0.0011 17.8 2.9 0.0011 17.8 2.0 1.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 KND91624.1 - 0.004 16.7 0.2 0.004 16.7 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KND91624.1 - 0.0041 17.2 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND91624.1 - 0.017 14.0 1.8 0.16 10.7 0.5 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND91624.1 - 0.029 14.7 0.1 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KND91624.1 - 0.11 12.8 0.5 0.49 10.6 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.9 KND91624.1 - 0.12 10.7 6.0 0.15 10.5 1.0 2.7 3 0 0 3 3 3 0 HI0933-like protein DUF2404 PF10296.4 KND91625.1 - 4.6e-08 33.0 0.0 7.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1628 PF07790.6 KND91625.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Snf7 PF03357.16 KND91626.1 - 1.3e-19 70.2 13.8 1.9e-19 69.7 9.6 1.3 1 0 0 1 1 1 1 Snf7 DUF4559 PF15112.1 KND91626.1 - 0.13 11.4 5.2 0.45 9.6 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Uds1 PF15456.1 KND91626.1 - 0.16 11.9 12.4 0.022 14.7 4.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation PVL_ORF50 PF07768.6 KND91626.1 - 3.3 7.7 5.8 0.89 9.5 1.0 2.1 2 1 1 3 3 3 0 PVL ORF-50-like family zf-C3HC4 PF00097.20 KND91627.1 - 6.6e-09 35.2 9.2 6.6e-09 35.2 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND91627.1 - 6.6e-08 32.1 11.8 1.1e-07 31.3 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND91627.1 - 1.1e-07 31.5 9.0 1.1e-07 31.5 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND91627.1 - 1.5e-07 31.3 9.8 1.5e-07 31.3 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND91627.1 - 1.7e-07 30.9 14.2 2.8e-07 30.2 6.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 KND91627.1 - 3.9e-06 26.5 2.4 3.9e-06 26.5 1.6 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KND91627.1 - 2.7e-05 23.9 9.2 2.7e-05 23.9 6.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND91627.1 - 0.00047 19.8 8.1 0.00047 19.8 5.6 2.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KND91627.1 - 0.00086 19.3 3.1 0.00086 19.3 2.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger SAP PF02037.22 KND91627.1 - 0.0015 18.0 0.9 0.0032 16.9 0.2 2.0 2 0 0 2 2 2 1 SAP domain zf-RING_4 PF14570.1 KND91627.1 - 0.0019 17.7 2.5 0.0019 17.7 1.7 2.7 2 1 0 3 3 3 1 RING/Ubox like zinc-binding domain Sgf11 PF08209.6 KND91627.1 - 0.0026 17.0 0.1 0.0086 15.3 0.1 1.9 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KND91627.1 - 0.0031 17.1 0.5 0.0031 17.1 0.3 2.9 3 0 0 3 3 3 1 zinc-finger of a C2HC-type Mob_synth_C PF06463.8 KND91627.1 - 0.0033 17.1 1.8 0.0033 17.1 1.2 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C U-box PF04564.10 KND91627.1 - 0.06 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain Rad50_zn_hook PF04423.9 KND91627.1 - 0.29 10.6 6.5 4.9 6.6 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 KND91627.1 - 0.45 10.3 4.9 0.078 12.8 0.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 KND91627.1 - 1.2 8.6 11.2 0.041 13.3 3.5 1.7 2 0 0 2 2 1 0 P-11 zinc finger Abhydrolase_1 PF00561.15 KND91628.1 - 0.00074 19.1 0.0 0.00075 19.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND91628.1 - 0.0034 17.2 0.1 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyoxalase_2 PF12681.2 KND91629.1 - 7.4e-07 29.7 0.1 8.5e-07 29.5 0.1 1.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KND91629.1 - 0.011 15.6 0.1 0.049 13.6 0.0 1.8 1 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_24 PF13578.1 KND91630.1 - 9.2e-09 36.0 0.0 2.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KND91630.1 - 0.047 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase FAD_binding_4 PF01565.18 KND91631.1 - 2.6e-21 75.5 0.9 5.2e-21 74.5 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND91631.1 - 3.9e-12 45.8 0.0 7.4e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Zot PF05707.7 KND91632.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Peptidase_S10 PF00450.17 KND91633.1 - 5.4e-128 427.6 0.9 6.6e-128 427.4 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase K_oxygenase PF13434.1 KND91634.1 - 1.6e-12 47.0 0.0 4.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KND91634.1 - 3.1e-10 40.4 0.0 7.8e-05 22.8 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND91634.1 - 1.7e-06 28.1 0.0 0.0047 16.8 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND91634.1 - 4.1e-05 23.3 0.1 0.038 13.7 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KND91634.1 - 4.5e-05 22.6 0.2 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KND91634.1 - 0.00063 18.3 0.0 0.16 10.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KND91634.1 - 0.004 17.1 0.1 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND91634.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KND91634.1 - 0.02 13.8 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 KND91634.1 - 0.031 13.2 0.5 0.55 9.0 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND91634.1 - 0.046 12.5 0.0 0.24 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KND91634.1 - 0.14 12.6 0.0 31 5.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M20 PF01546.23 KND91635.1 - 1.6e-16 60.3 0.1 3.9e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND91635.1 - 0.00011 21.8 0.1 0.00034 20.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Syndecan PF01034.15 KND91635.1 - 0.027 14.1 0.2 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 KND91635.1 - 0.043 14.2 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KND91635.1 - 0.081 12.2 1.0 0.18 11.1 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF908 PF06012.7 KND91635.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Alpha_GJ PF03229.8 KND91635.1 - 4.8 7.5 19.0 0.16 12.3 8.0 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF3638 PF12340.3 KND91636.1 - 4.6e-90 300.5 0.1 5.7e-90 300.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF815 PF05673.8 KND91636.1 - 0.039 12.8 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Chitin_synth_1 PF01644.12 KND91637.1 - 7.8e-84 279.4 0.1 1.4e-83 278.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KND91637.1 - 1.6e-32 111.0 0.2 3.7e-32 109.8 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KND91637.1 - 3.1e-24 85.2 0.7 3.1e-21 75.3 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KND91637.1 - 1.4e-08 34.6 5.2 7.2e-08 32.3 3.6 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND91637.1 - 2.1e-06 27.7 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Sugar_tr PF00083.19 KND91638.1 - 2.5e-91 306.5 27.8 3.1e-91 306.2 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91638.1 - 4.4e-21 74.9 19.5 4.4e-21 74.9 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HupE_UreJ_2 PF13795.1 KND91638.1 - 0.067 12.6 0.8 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Kei1 PF08552.6 KND91639.1 - 2.4e-45 154.5 9.2 7.4e-45 152.9 6.4 1.7 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 7TMR-DISM_7TM PF07695.6 KND91639.1 - 1.4 8.5 12.7 0.051 13.2 4.6 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2975 PF11188.3 KND91639.1 - 2.4 7.8 6.7 0.34 10.6 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) SPC12 PF06645.8 KND91639.1 - 8.3 6.2 6.2 0.79 9.5 0.9 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NIR_SIR PF01077.17 KND91640.1 - 5.6e-50 168.7 0.1 3.9e-45 153.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KND91640.1 - 7.2e-31 105.6 0.0 2.4e-15 55.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KND91640.1 - 3.5e-27 95.1 0.0 8.4e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KND91640.1 - 5.2e-06 26.1 0.4 1.9e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Nop53 PF07767.6 KND91641.1 - 2.5e-101 339.5 30.7 2.9e-101 339.2 21.3 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.17 KND91642.1 - 5.8e-60 201.3 0.4 7.6e-60 200.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND91642.1 - 1.3e-21 77.2 0.1 2.4e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND91642.1 - 1.8e-18 66.4 0.3 2.2e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND91642.1 - 7.1e-08 32.1 0.1 3.3e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KND91642.1 - 2.8e-06 26.6 0.5 3.6e-06 26.2 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND91642.1 - 7.7e-06 25.8 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KND91642.1 - 8.5e-06 25.0 0.1 1.3e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KND91642.1 - 0.0057 16.2 0.2 0.017 14.6 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Glyco_tran_WbsX PF14307.1 KND91642.1 - 0.025 13.7 0.1 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX Dynamin_N PF00350.18 KND91642.1 - 0.03 14.1 0.2 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 KND91642.1 - 0.073 13.0 0.0 7.9 6.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain MobB PF03205.9 KND91642.1 - 0.08 12.6 0.2 4 7.1 0.0 2.5 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KND91642.1 - 0.083 12.7 0.3 0.18 11.7 0.2 1.6 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KND91642.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase PRK PF00485.13 KND91643.1 - 8.1e-57 191.9 0.0 1.2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KND91643.1 - 3.8e-40 137.3 0.0 5.9e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KND91643.1 - 4.3e-11 43.6 0.0 1.4e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND91643.1 - 1.6e-06 28.4 0.0 4.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND91643.1 - 2.2e-06 27.5 0.1 2.4e-05 24.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KND91643.1 - 7.5e-06 25.6 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 KND91643.1 - 0.0022 17.1 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 KND91643.1 - 0.0055 17.0 0.0 0.017 15.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KND91643.1 - 0.0069 15.8 0.2 0.024 14.1 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 KND91643.1 - 0.0078 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.9 KND91643.1 - 0.0083 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KND91643.1 - 0.019 14.9 0.0 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KND91643.1 - 0.031 13.1 0.1 0.076 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 KND91643.1 - 0.035 14.2 0.2 0.37 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain Pribosyltran PF00156.22 KND91643.1 - 0.037 13.7 0.0 0.76 9.5 0.0 2.5 3 0 0 3 3 3 0 Phosphoribosyl transferase domain DUF87 PF01935.12 KND91643.1 - 0.041 13.7 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF258 PF03193.11 KND91643.1 - 0.091 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KND91643.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 KND91643.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 KND91643.1 - 0.16 12.1 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Pyr_redox_2 PF07992.9 KND91644.1 - 2.2e-22 79.9 0.0 3.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND91644.1 - 2.7e-15 56.5 0.0 3.4e-11 43.3 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KND91644.1 - 8.7e-07 27.8 0.3 1.8e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KND91644.1 - 1.3e-05 25.2 0.2 4.1e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KND91644.1 - 2.7e-05 23.6 0.5 9.1e-05 22.0 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KND91644.1 - 9.4e-05 21.5 1.5 0.00021 20.5 1.1 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 KND91644.1 - 0.0012 18.9 0.1 1.2 9.1 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 KND91644.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ETC_C1_NDUFA4 PF04800.7 KND91645.1 - 5.4e-36 122.5 0.7 8.3e-36 121.8 0.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.4 KND91646.1 - 8.8e-33 113.0 0.2 1.1e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KND91646.1 - 0.057 13.2 0.2 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 LisH TPR_14 PF13428.1 KND91646.1 - 0.34 11.6 2.2 10 7.1 0.0 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat Macro PF01661.16 KND91647.1 - 2.2e-39 134.0 0.0 3e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Macro domain PKD_channel PF08016.7 KND91648.1 - 0.00027 19.4 17.8 0.0061 15.0 11.8 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KND91648.1 - 0.0021 17.3 25.8 0.025 13.8 17.9 2.3 1 1 0 1 1 1 1 Ion transport protein tRNA-synt_1c PF00749.16 KND91649.1 - 2.3e-98 328.7 0.1 3.8e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KND91649.1 - 3.4e-30 104.9 0.0 2.4e-29 102.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Rib_5-P_isom_A PF06026.9 KND91650.1 - 3.8e-38 130.5 0.0 8.4e-36 122.8 0.0 2.2 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) C6 PF01681.12 KND91651.1 - 0.043 13.8 4.8 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 C6 domain DUF1308 PF07000.6 KND91652.1 - 2.3e-42 144.9 0.0 5.2e-42 143.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF2285 PF10074.4 KND91652.1 - 0.014 15.7 0.2 5.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2285) End_beta_barrel PF12195.3 KND91653.1 - 0.11 12.1 1.0 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase AAA PF00004.24 KND91654.1 - 1.8e-15 57.3 0.0 4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KND91654.1 - 6.5e-05 22.6 0.1 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KND91654.1 - 0.0051 16.9 1.6 0.06 13.4 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KND91654.1 - 0.0065 17.2 0.0 0.023 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND91654.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KND91654.1 - 0.024 14.6 0.2 0.077 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.1 KND91654.1 - 0.057 12.9 0.0 0.057 12.9 0.0 2.4 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KND91654.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KND91654.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Prefoldin_2 PF01920.15 KND91654.1 - 7.6 6.3 8.7 6.8 6.5 0.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit Fungal_trans PF04082.13 KND91656.1 - 4.2e-12 45.4 0.0 6.1e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91656.1 - 5.7e-09 35.7 9.6 1.2e-08 34.7 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSrecog PF03531.9 KND91657.1 - 4.2e-68 228.9 2.6 4.1e-34 117.8 0.1 3.2 2 1 0 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KND91657.1 - 4.9e-25 87.3 0.0 2.4e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 KND91657.1 - 0.048 12.8 0.0 0.048 12.8 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Lipase_3 PF01764.20 KND91658.1 - 9.2e-07 28.5 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 KND91658.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KND91658.1 - 0.16 11.5 0.5 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein YL1 PF05764.8 KND91659.1 - 8e-59 199.1 22.9 8e-59 199.1 15.9 3.7 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.6 KND91659.1 - 7.4e-12 44.6 0.4 1.3e-11 43.8 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain APH PF01636.18 KND91659.1 - 0.87 9.2 6.9 2.1 8.0 4.8 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FA_hydroxylase PF04116.8 KND91661.1 - 2.5e-19 69.7 10.3 2.5e-19 69.7 7.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 KND91662.1 - 4.2e-61 205.7 0.7 4.7e-61 205.5 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PRMT5 PF05185.11 KND91662.1 - 0.13 11.1 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Mis12 PF05859.7 KND91664.1 - 1.1e-32 112.8 0.0 1.9e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein PPR_2 PF13041.1 KND91665.1 - 2.1e-18 66.0 0.0 0.0047 16.8 0.0 7.2 7 1 1 8 8 8 3 PPR repeat family PPR_3 PF13812.1 KND91665.1 - 4e-15 54.7 9.9 0.0016 18.5 0.0 9.3 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 KND91665.1 - 2.2e-08 33.5 0.0 0.18 11.8 0.3 5.9 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 KND91665.1 - 6.7e-05 22.2 0.0 0.44 10.0 0.0 4.0 4 0 0 4 4 4 2 PPR repeat RPM2 PF08579.6 KND91665.1 - 0.055 13.6 0.0 0.64 10.1 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TcpQ PF10671.4 KND91665.1 - 0.071 12.9 0.0 9.7 6.1 0.0 2.7 1 1 1 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q TPR_14 PF13428.1 KND91665.1 - 0.1 13.2 0.4 0.1 13.2 0.3 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Glyoxalase PF00903.20 KND91665.1 - 0.1 12.5 0.1 4.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GST_C_2 PF13410.1 KND91666.1 - 1.1e-06 28.3 0.1 2.1e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KND91666.1 - 6.4e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KND91666.1 - 1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KND91666.1 - 2.2e-05 24.5 0.0 6.9e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND91666.1 - 3.7e-05 23.6 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KND91666.1 - 0.0015 18.4 0.0 0.0043 17.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 KND91668.1 - 6.7e-27 94.2 0.0 1.8e-26 92.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91668.1 - 8.2e-05 21.7 0.4 0.0029 16.7 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND91668.1 - 0.032 13.9 0.3 0.067 12.9 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Varsurf_PPLC PF03490.8 KND91669.1 - 0.056 13.1 0.2 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Sod_Fe_C PF02777.13 KND91670.1 - 1.7e-38 130.7 0.1 2.9e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KND91670.1 - 4.2e-30 103.8 0.8 7.3e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Phage_capsid PF05065.8 KND91670.1 - 0.019 14.1 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Phage capsid family Sld5 PF05916.6 KND91671.1 - 6e-10 39.3 0.0 8.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein APH PF01636.18 KND91673.1 - 1.1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Microtub_assoc PF07989.6 KND91674.1 - 0.0021 17.8 2.1 0.0048 16.6 1.4 1.7 1 0 0 1 1 1 1 Microtubule associated Glyco_transf_54 PF04666.8 KND91675.1 - 1.2e-11 43.8 0.0 1.4e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region PgaD PF13994.1 KND91675.1 - 0.023 14.1 1.1 0.023 14.1 0.8 2.0 2 0 0 2 2 2 0 PgaD-like protein YbhQ PF11076.3 KND91675.1 - 0.091 12.3 0.3 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DUF2269 PF10027.4 KND91675.1 - 0.89 9.3 4.9 0.18 11.5 0.6 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF2910 PF11139.3 KND91675.1 - 1.1 8.3 6.2 0.27 10.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) zf-BED PF02892.10 KND91676.1 - 2.5 7.9 4.8 3.7 7.3 0.3 2.6 2 0 0 2 2 2 0 BED zinc finger PRKCSH PF07915.8 KND91677.1 - 1.9e-16 60.6 0.0 5.7e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Tom37 PF10568.4 KND91678.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF2731 PF10806.3 KND91678.1 - 0.017 15.3 0.0 0.069 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2731) GST_C_3 PF14497.1 KND91678.1 - 0.038 14.4 0.1 0.087 13.3 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND91678.1 - 0.081 12.8 3.0 0.3 11.0 2.1 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain OTU PF02338.14 KND91679.1 - 1.8e-18 67.2 0.1 1e-17 64.8 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KND91679.1 - 0.005 16.2 0.0 0.69 9.2 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain Ebola_NP PF05505.7 KND91679.1 - 0.8 7.7 12.9 1.1 7.2 8.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein BNIP3 PF06553.7 KND91679.1 - 1.7 7.9 12.2 0.4 10.0 6.1 1.5 1 1 1 2 2 2 0 BNIP3 Spore_coat_CotO PF14153.1 KND91679.1 - 6.9 6.0 22.2 4.9 6.5 8.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO INO80_Ies4 PF08193.6 KND91680.1 - 2.1e-64 217.5 20.1 2.7e-64 217.1 13.9 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 KND91681.1 - 1.8e-31 108.7 0.2 3.7e-31 107.7 0.0 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KND91681.1 - 2.9e-23 82.2 0.1 4.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KND91681.1 - 0.00016 21.3 0.1 0.0005 19.7 0.0 1.9 2 0 0 2 2 2 1 LisH DUF387 PF04079.11 KND91681.1 - 0.0041 16.4 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) IDO PF01231.13 KND91682.1 - 1.2e-40 139.2 0.0 1.6e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CDC14 PF08045.6 KND91683.1 - 1.7e-90 302.6 0.0 2e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Pex24p PF06398.6 KND91685.1 - 4.7e-92 308.5 0.0 5.4e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 KND91685.1 - 0.005 14.7 0.7 0.0086 14.0 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) DUF639 PF04842.7 KND91685.1 - 0.038 12.1 0.6 0.068 11.3 0.2 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) polyprenyl_synt PF00348.12 KND91686.1 - 1.6e-55 187.7 0.0 1.9e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Cortexin PF11057.3 KND91686.1 - 0.05 13.1 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Cortexin of kidney GRIP PF01465.15 KND91687.1 - 5.5e-16 57.8 0.0 1.2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 GRIP domain TPR_MLP1_2 PF07926.7 KND91687.1 - 0.00035 20.3 139.1 0.034 13.8 15.4 8.7 3 2 5 8 8 8 6 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 KND91687.1 - 0.00048 19.5 7.8 0.00048 19.5 5.4 11.5 4 2 7 12 12 12 4 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 KND91687.1 - 0.001 18.9 148.2 0.2 11.5 11.5 8.5 3 2 4 8 8 8 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KND91687.1 - 0.0019 17.4 47.5 0.066 12.3 2.2 7.6 3 2 5 8 8 8 4 Reovirus sigma C capsid protein GAS PF13851.1 KND91687.1 - 0.011 14.9 138.4 0.039 13.1 12.6 8.8 3 3 5 8 8 8 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KND91687.1 - 0.29 10.6 144.8 0.71 9.4 15.0 8.3 3 2 4 8 8 8 0 IncA protein Myosin_tail_1 PF01576.14 KND91687.1 - 0.31 8.7 154.7 0.11 10.1 12.9 6.2 3 1 1 5 5 5 0 Myosin tail AAA_13 PF13166.1 KND91687.1 - 0.87 7.9 112.4 0.13 10.6 16.8 5.5 2 2 3 5 5 5 0 AAA domain DUF2296 PF10058.4 KND91688.1 - 1.1e-18 66.7 0.1 1.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF605 PF04652.11 KND91688.1 - 0.053 12.9 11.3 0.083 12.2 7.8 1.2 1 0 0 1 1 1 0 Vta1 like ABC_membrane_3 PF13748.1 KND91688.1 - 0.057 12.4 0.2 0.098 11.6 0.1 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region ALIX_LYPXL_bnd PF13949.1 KND91688.1 - 0.099 11.5 0.2 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV RNase_H PF00075.19 KND91689.1 - 3e-16 59.9 0.0 4.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KND91689.1 - 0.029 14.1 0.0 6 6.7 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like NACHT PF05729.7 KND91690.1 - 2.6e-23 82.4 0.0 4.3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND91690.1 - 2.1e-05 24.5 0.4 0.00028 20.9 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KND91690.1 - 0.00038 20.1 0.0 0.011 15.4 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KND91690.1 - 0.0064 16.6 0.0 0.029 14.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain DAO PF01266.19 KND91692.1 - 5.9e-35 120.8 1.3 9.3e-35 120.1 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND91692.1 - 0.00043 20.3 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND91692.1 - 0.00057 18.8 0.4 0.0011 17.9 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND91692.1 - 0.0029 17.5 0.1 0.0077 16.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND91692.1 - 0.014 15.1 0.7 0.05 13.3 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND91692.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND91692.1 - 0.13 11.2 0.1 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Transaldolase PF00923.14 KND91694.1 - 2.9e-46 157.8 0.0 3.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Peptidase_M48 PF01435.13 KND91695.1 - 0.087 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 DUF4360 PF14273.1 KND91696.1 - 2.7e-39 134.7 0.2 3.1e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Rep_fac-A_C PF08646.5 KND91697.1 - 3.5e-38 130.5 3.0 1.4e-36 125.3 0.9 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KND91697.1 - 4.4e-20 71.3 0.0 8e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KND91697.1 - 1.1e-13 50.7 1.3 4.1e-10 39.3 0.0 3.3 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain ADH_zinc_N PF00107.21 KND91698.1 - 5.8e-24 84.0 0.1 9.6e-24 83.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND91698.1 - 1.5e-17 64.6 0.1 3.8e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND91698.1 - 1.6e-11 43.9 0.0 6.7e-11 41.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PSII_BNR PF14870.1 KND91698.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Kinetocho_Slk19 PF12709.2 KND91699.1 - 1.5e-22 79.4 0.8 1.5e-22 79.4 0.6 5.9 5 2 2 7 7 7 2 Central kinetochore-associated FlaC_arch PF05377.6 KND91699.1 - 0.053 13.4 0.3 0.053 13.4 0.2 5.1 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Amidohydro_2 PF04909.9 KND91700.1 - 2.4e-22 79.8 0.2 3.1e-22 79.4 0.1 1.2 1 1 0 1 1 1 1 Amidohydrolase DNA_pol_viral_N PF00242.12 KND91701.1 - 0.0054 15.8 17.9 0.0054 15.8 12.4 1.8 2 0 0 2 2 2 1 DNA polymerase (viral) N-terminal domain CDC45 PF02724.9 KND91701.1 - 0.54 8.2 7.1 0.68 7.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.8 KND91701.1 - 0.97 8.5 9.7 1.2 8.2 6.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sec3_C PF09763.4 KND91701.1 - 1.5 6.8 9.2 1.8 6.5 6.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Zip PF02535.17 KND91701.1 - 4.3 6.2 7.7 5.9 5.7 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 KND91701.1 - 9.5 6.2 14.4 26 4.8 7.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 KND91701.1 - 9.7 5.9 27.4 0.74 9.5 12.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) LSM PF01423.17 KND91702.1 - 3.1e-19 68.2 0.0 4e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND91702.1 - 0.035 14.0 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 KND91702.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DLH PF01738.13 KND91703.1 - 6.8e-21 74.5 0.1 1.6e-19 70.0 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND91703.1 - 4e-09 36.3 0.2 6.1e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND91703.1 - 9.3e-05 22.4 2.0 0.13 12.1 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND91703.1 - 0.00048 19.7 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KND91703.1 - 0.0054 16.3 0.4 0.12 11.8 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold AMP-binding PF00501.23 KND91705.1 - 1.3e-76 257.6 0.1 1.6e-76 257.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND91705.1 - 1.6e-16 61.0 1.5 1.9e-16 60.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KilA-N PF04383.8 KND91706.1 - 0.00024 20.6 0.0 0.0036 16.9 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain DUF2300 PF10062.4 KND91707.1 - 0.4 10.4 3.6 0.34 10.6 0.3 2.3 2 1 0 2 2 2 0 Predicted secreted protein (DUF2300) TPR_12 PF13424.1 KND91708.1 - 3e-55 184.0 11.9 9.8e-22 76.6 0.1 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KND91708.1 - 5.2e-39 131.0 13.6 3.6e-12 45.7 0.0 5.8 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 KND91708.1 - 4.5e-15 54.1 3.2 0.0016 18.1 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KND91708.1 - 9e-14 50.8 0.5 7.7e-06 25.4 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KND91708.1 - 5.1e-12 44.8 1.4 0.011 15.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND91708.1 - 6e-09 36.1 1.7 0.06 13.6 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND91708.1 - 8.4e-09 34.6 3.0 0.19 11.7 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF676 PF05057.9 KND91708.1 - 4.3e-08 32.7 0.0 1e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) TPR_17 PF13431.1 KND91708.1 - 6.1e-08 32.2 2.1 0.089 13.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND91708.1 - 2.7e-07 31.0 0.5 0.012 16.2 0.0 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KND91708.1 - 6.5e-07 29.4 0.1 1.5e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Apc3 PF12895.2 KND91708.1 - 2.1e-05 24.5 1.4 0.17 12.0 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Abhydrolase_5 PF12695.2 KND91708.1 - 0.00012 21.8 0.0 0.00037 20.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_4 PF07721.9 KND91708.1 - 0.00015 21.8 0.0 9.2 7.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND91708.1 - 0.0013 18.3 7.1 4.9 7.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat PGAP1 PF07819.8 KND91708.1 - 0.0022 17.6 0.0 0.0074 15.9 0.0 1.9 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 KND91708.1 - 0.0024 16.8 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase TPR_3 PF07720.7 KND91708.1 - 0.0048 16.6 3.1 24 4.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3366 PF11846.3 KND91708.1 - 0.012 15.4 2.8 12 5.6 0.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3366) DUF726 PF05277.7 KND91708.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TPR_14 PF13428.1 KND91708.1 - 0.025 15.1 4.7 28 5.7 0.1 4.9 2 2 2 4 4 4 0 Tetratricopeptide repeat Lipase_3 PF01764.20 KND91708.1 - 0.078 12.5 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) TPR_6 PF13174.1 KND91708.1 - 0.11 12.9 6.2 13 6.5 0.2 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1925 PF09094.6 KND91708.1 - 0.22 11.5 4.8 31 4.6 0.0 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF1925) Pkinase PF00069.20 KND91709.1 - 4.3e-45 153.8 0.0 6.3e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91709.1 - 7.1e-24 84.2 0.0 9.5e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KND91709.1 - 3.4e-06 27.0 0.1 7.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KND91709.1 - 7.4e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND91709.1 - 0.022 14.5 0.0 0.069 12.8 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.18 KND91712.1 - 0.00065 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1e PF01406.14 KND91713.1 - 6.3e-109 363.7 0.0 1e-108 363.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KND91713.1 - 0.014 14.0 0.2 0.72 8.4 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (M) APH PF01636.18 KND91714.1 - 5.3e-24 85.2 0.1 6.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND91714.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND91714.1 - 0.015 14.6 0.0 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 KND91714.1 - 0.036 13.0 0.0 0.29 10.0 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 KND91714.1 - 0.063 12.4 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase DUF1237 PF06824.6 KND91715.1 - 1.9e-111 372.6 0.0 4.1e-90 302.3 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1237) WD40 PF00400.27 KND91718.1 - 1.3e-16 59.7 4.6 0.015 15.2 0.0 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat HAD_2 PF13419.1 KND91719.1 - 1e-13 51.9 0.0 1.8e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND91719.1 - 6.1e-05 23.5 0.0 0.0056 17.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND91719.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.3 KND91721.1 - 4.9e-09 35.2 0.6 9.7e-09 34.2 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_11 PF13414.1 KND91722.1 - 9.1e-10 38.0 0.8 9.1e-10 38.0 0.6 1.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KND91722.1 - 8.8e-07 28.7 0.7 2.6e-06 27.2 0.3 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND91722.1 - 0.00062 19.4 5.3 0.29 11.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND91722.1 - 0.0013 18.2 2.6 0.028 14.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND91722.1 - 0.0018 18.5 0.5 0.0052 17.0 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND91722.1 - 0.0043 17.6 2.0 0.0043 17.6 1.4 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KND91722.1 - 0.0053 16.8 0.9 0.012 15.6 0.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KND91722.1 - 0.0058 16.3 4.5 0.15 11.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND91722.1 - 0.047 14.3 6.0 2.6 8.9 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND91722.1 - 4.9 7.8 8.0 30 5.3 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KND91724.1 - 2e-46 158.5 22.3 1.9e-45 155.3 15.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91724.1 - 5.9e-18 64.7 32.8 4.1e-09 35.6 10.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 KND91724.1 - 0.0013 18.8 14.1 0.02 14.9 2.1 3.6 3 0 0 3 3 3 2 Protein of unknown function, DUF606 Fungal_trans PF04082.13 KND91725.1 - 1.3e-11 43.8 0.0 2.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91725.1 - 6.8e-06 25.8 7.2 1.4e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KND91726.1 - 1.4e-28 99.6 27.1 5.4e-28 97.7 18.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91726.1 - 5.7e-28 97.6 37.6 3.2e-21 75.4 14.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF647 PF04884.9 KND91727.1 - 1.3e-88 296.3 2.9 3.1e-88 295.1 2.0 1.6 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis GHMP_kinases_N PF00288.21 KND91727.1 - 6.7e-08 32.4 1.3 6.7e-08 32.4 0.9 2.8 4 0 0 4 4 4 1 GHMP kinases N terminal domain DUF4405 PF14358.1 KND91727.1 - 0.99 9.5 3.6 0.98 9.6 0.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) APH PF01636.18 KND91728.1 - 2.5e-14 53.6 0.2 6.7e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KND91728.1 - 3.8e-05 23.4 5.9 7.8e-05 22.4 4.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Prok-RING_2 PF14445.1 KND91728.1 - 0.08 12.9 2.7 0.18 11.7 1.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 HMGL-like PF00682.14 KND91730.1 - 1.8e-68 230.7 0.2 2.7e-68 230.1 0.2 1.3 1 0 0 1 1 1 1 HMGL-like NPP PF08384.5 KND91730.1 - 0.2 11.3 0.5 0.69 9.5 0.1 2.0 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region WSC PF01822.14 KND91732.1 - 3.5e-58 193.4 79.7 5.2e-18 64.7 8.5 5.7 5 1 0 5 5 5 4 WSC domain PQQ_3 PF13570.1 KND91732.1 - 0.00018 21.6 12.9 0.11 12.7 0.0 4.9 4 0 0 4 4 4 2 PQQ-like domain Mitofilin PF09731.4 KND91732.1 - 8 4.9 8.0 11 4.4 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tn916-Xis PF09035.5 KND91733.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Excisionase from transposon Tn916 DUF427 PF04248.7 KND91734.1 - 7.6e-32 108.8 0.0 9.9e-27 92.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Acetyltransf_8 PF13523.1 KND91735.1 - 6.1e-32 110.6 0.2 8.9e-32 110.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF607 PF04678.8 KND91736.1 - 3.8e-37 127.9 0.3 2.7e-36 125.1 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Glyco_trans_4_4 PF13579.1 KND91736.1 - 0.0086 16.2 0.3 0.02 15.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ArfGap PF01412.13 KND91737.1 - 2.2e-39 133.8 0.5 4.3e-39 132.9 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Haem_bd PF14376.1 KND91737.1 - 0.051 13.2 0.6 0.12 12.0 0.4 1.7 1 0 0 1 1 1 0 Haem-binding domain UBA PF00627.26 KND91737.1 - 0.15 11.9 0.1 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Oxysterol_BP PF01237.13 KND91738.1 - 6.3e-108 360.4 0.0 2.2e-107 358.6 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KND91738.1 - 9.9e-38 128.1 0.5 2.9e-37 126.6 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KND91738.1 - 6.9e-05 23.0 0.0 0.00028 21.0 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KND91738.1 - 0.0064 16.7 1.9 0.38 11.0 0.9 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain Tbf5 PF06331.7 KND91739.1 - 6.7e-26 89.8 1.5 9e-26 89.4 1.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF177 PF02620.12 KND91739.1 - 0.067 13.2 0.2 0.088 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 Mito_carr PF00153.22 KND91740.1 - 5.7e-49 163.7 3.7 4.1e-18 64.8 0.1 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.12 KND91741.1 - 3.3e-46 155.8 1.5 5.6e-46 155.1 1.0 1.3 1 0 0 1 1 1 1 Ribosomal L22e protein family His_biosynth PF00977.16 KND91744.1 - 1e-46 159.0 0.1 4.5e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KND91744.1 - 9e-26 90.5 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KND91744.1 - 1.3e-07 31.4 0.0 1.6e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KND91744.1 - 1.2e-06 28.1 0.1 2.9e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 KND91744.1 - 0.0028 16.5 0.0 0.0063 15.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 KND91744.1 - 0.099 12.0 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 ODC_AZ PF02100.12 KND91745.1 - 2.2e-26 91.4 0.1 3.4e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ank_2 PF12796.2 KND91746.1 - 1.2e-56 189.0 5.5 1.1e-14 54.4 0.1 6.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KND91746.1 - 9.2e-52 170.3 12.1 2.1e-07 30.3 0.0 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 KND91746.1 - 7.5e-42 140.9 12.3 2e-09 37.6 0.0 9.4 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND91746.1 - 2.4e-33 110.8 9.0 0.00014 21.7 0.0 12.2 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 KND91746.1 - 1.6e-30 104.4 14.5 4.2e-08 33.1 0.0 8.1 4 2 3 8 8 8 6 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KND91746.1 - 2.7e-05 23.2 0.0 4.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KND91746.1 - 0.021 14.4 0.2 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain MFS_1 PF07690.11 KND91749.1 - 4e-35 121.1 48.0 4e-35 121.1 33.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND91749.1 - 5.5e-10 38.4 15.7 5.5e-10 38.4 10.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KND91749.1 - 1.9e-07 29.8 10.1 1.9e-07 29.8 7.0 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein APH PF01636.18 KND91751.1 - 3.6e-12 46.5 0.0 8.2e-12 45.3 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 KND91752.1 - 1.6e-17 63.2 0.1 2.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.9 KND91753.1 - 7.5e-57 192.5 0.0 1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Amidohydro_2 PF04909.9 KND91754.1 - 3.7e-20 72.6 0.5 4.4e-20 72.3 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 KND91755.1 - 1.8e-08 33.5 27.2 1.8e-05 23.6 3.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SRR1 PF07985.7 KND91756.1 - 3.4e-05 23.6 0.0 5.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 SRR1 APH PF01636.18 KND91757.1 - 3.8e-13 49.7 0.1 2.5e-12 47.0 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_17 PF00332.13 KND91759.1 - 0.00019 20.6 2.2 0.06 12.3 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3112 PF11309.3 KND91759.1 - 0.38 10.5 0.6 0.61 9.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Zn_clus PF00172.13 KND91761.1 - 4.3e-07 29.7 2.1 7.8e-07 28.9 1.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KND91762.1 - 6.7e-17 60.6 9.4 0.015 15.2 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Nop14 PF04147.7 KND91762.1 - 0.057 11.3 16.9 0.086 10.7 11.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KND91762.1 - 0.29 9.1 10.3 0.47 8.4 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 KND91762.1 - 6.7 6.4 8.7 19 4.9 6.0 1.8 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit AAA_12 PF13087.1 KND91763.1 - 5.2e-32 110.8 0.0 1.6e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KND91763.1 - 1e-21 77.5 0.0 2.2e-21 76.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND91763.1 - 2.3e-07 30.4 0.1 1.2e-06 28.1 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KND91763.1 - 1.3e-06 28.1 0.1 0.00067 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KND91763.1 - 0.034 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KND91763.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 KND91763.1 - 0.16 10.8 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ank_2 PF12796.2 KND91764.1 - 2.5e-07 30.9 0.0 9.5e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KND91764.1 - 2.6e-07 30.0 0.2 1.7e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KND91764.1 - 0.00035 20.7 0.1 0.0016 18.5 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND91764.1 - 0.0013 18.7 0.0 0.018 15.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KND91764.1 - 0.0094 16.4 0.1 0.084 13.4 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) NACHT PF05729.7 KND91764.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Methyltransf_23 PF13489.1 KND91765.1 - 1.4e-10 41.0 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91765.1 - 1.7e-05 25.1 0.0 3.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND91765.1 - 0.0003 21.1 0.0 0.0016 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND91765.1 - 0.0046 16.1 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SGL PF08450.7 KND91766.1 - 0.0035 16.7 0.0 0.007 15.7 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 KND91766.1 - 0.0052 17.0 1.6 7.2 7.0 0.0 3.0 2 1 0 2 2 2 2 PQQ-like domain GCD14 PF08704.5 KND91767.1 - 0.019 14.4 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DNA_primase_lrg PF04104.9 KND91768.1 - 2.6e-80 269.4 0.0 4.7e-80 268.6 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Phage_tail_L PF05100.7 KND91768.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein L Mut7-C PF01927.11 KND91769.1 - 0.017 15.1 0.2 0.018 15.0 0.2 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-FPG_IleRS PF06827.9 KND91769.1 - 0.023 14.3 1.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF164 PF02591.10 KND91769.1 - 0.029 14.2 0.8 0.04 13.7 0.6 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF3268 PF11672.3 KND91769.1 - 0.041 13.9 1.0 0.053 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) DUF1660 PF07874.6 KND91769.1 - 0.29 11.4 3.7 4.6 7.5 0.1 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) GP40 PF11025.3 KND91769.1 - 0.75 9.3 5.2 0.88 9.1 3.6 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Carla_C4 PF01623.12 KND91769.1 - 1.2 8.9 6.2 2 8.2 0.8 2.2 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein Clr5 PF14420.1 KND91770.1 - 4.5e-20 71.2 0.7 9.1e-20 70.3 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain Pkinase PF00069.20 KND91771.1 - 5.1e-48 163.4 0.0 2.1e-47 161.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND91771.1 - 3.2e-28 98.5 0.0 5.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cupin_2 PF07883.6 KND91772.1 - 1e-14 53.7 1.0 1.4e-14 53.3 0.7 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KND91772.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 KND91772.1 - 0.038 13.6 0.5 0.052 13.2 0.3 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Lipase_3 PF01764.20 KND91773.1 - 8.4e-32 109.7 0.0 1.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KND91773.1 - 8.3e-06 25.6 0.1 1.4e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND91773.1 - 2.6e-05 24.2 1.3 4e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KND91773.1 - 0.013 15.0 1.1 0.019 14.4 0.4 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase Cutinase PF01083.17 KND91773.1 - 0.014 15.1 0.1 0.037 13.7 0.1 1.7 1 1 0 1 1 1 0 Cutinase Thioesterase PF00975.15 KND91773.1 - 0.058 13.6 0.7 0.098 12.8 0.5 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 KND91773.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KND91773.1 - 0.11 11.7 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2048 PF09752.4 KND91773.1 - 0.15 10.9 0.4 0.23 10.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LRR_6 PF13516.1 KND91774.1 - 0.00012 21.8 2.7 0.82 9.9 0.0 6.2 7 0 0 7 7 7 1 Leucine Rich repeat NinF PF05810.7 KND91774.1 - 0.28 11.0 1.9 8.8 6.2 0.0 3.1 3 0 0 3 3 3 0 NinF protein SNF2_N PF00176.18 KND91775.1 - 2.8e-61 206.9 0.1 4.9e-61 206.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND91775.1 - 6.6e-12 45.1 0.0 1.5e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KND91775.1 - 1.2e-06 28.0 11.2 1.2e-06 28.0 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND91775.1 - 0.0011 18.7 12.5 0.0011 18.7 8.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND91775.1 - 0.0046 16.9 11.7 0.0046 16.9 8.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND91775.1 - 0.0062 16.1 11.0 0.0062 16.1 7.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 KND91775.1 - 0.053 12.2 0.0 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 zf-RING_6 PF14835.1 KND91775.1 - 0.43 10.3 5.5 1 9.1 3.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KND91775.1 - 1.3 8.5 10.0 0.27 10.7 3.9 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit EF1_GNE PF00736.14 KND91776.1 - 1.6e-27 94.9 2.8 3.4e-27 93.9 1.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KND91776.1 - 1.1e-12 47.8 7.8 1.1e-12 47.8 5.4 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KND91776.1 - 0.012 16.0 0.1 0.032 14.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KND91776.1 - 0.019 14.9 0.0 0.059 13.3 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Orn_Arg_deC_N PF02784.11 KND91777.1 - 3.1e-79 265.7 0.0 4.2e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KND91777.1 - 1.9e-29 101.7 0.0 4.4e-29 100.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain M16C_assoc PF08367.6 KND91778.1 - 1.8e-57 194.0 0.0 3.5e-57 193.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KND91778.1 - 1.9e-30 105.9 0.0 3.3e-17 62.7 0.0 3.6 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND91778.1 - 1.5e-07 31.3 0.0 5.6e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) THDPS_N_2 PF14805.1 KND91778.1 - 0.035 13.9 0.4 0.085 12.7 0.3 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Taxilin PF09728.4 KND91779.1 - 2e-82 276.7 54.4 3.1e-82 276.1 37.7 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.3 KND91779.1 - 0.0043 16.7 7.2 0.0043 16.7 5.0 5.1 3 2 2 5 5 5 2 TATA element modulatory factor 1 TATA binding Sec20 PF03908.8 KND91779.1 - 3 7.6 13.2 0.38 10.4 0.7 3.9 3 1 1 4 4 4 0 Sec20 ArdA PF07275.6 KND91779.1 - 5.1 7.3 10.2 0.51 10.5 3.1 2.3 2 0 0 2 2 2 0 Antirestriction protein (ArdA) Peptidase_M48 PF01435.13 KND91780.1 - 5.3e-48 163.5 0.1 7.6e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KND91780.1 - 3.2e-06 26.3 0.0 5.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M16_C PF05193.16 KND91781.1 - 4.9e-17 62.2 0.0 3.4e-12 46.4 0.0 3.5 4 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND91781.1 - 1.9e-08 34.2 0.0 3.7e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) CDC45 PF02724.9 KND91781.1 - 2.1 6.3 3.5 2.8 5.8 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KND91781.1 - 2.5 5.9 6.4 3.2 5.5 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family Methyltransf_24 PF13578.1 KND91782.1 - 9e-11 42.5 0.0 1.6e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KND91782.1 - 9.9e-09 34.5 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase ADH_zinc_N PF00107.21 KND91782.1 - 0.002 17.6 1.0 0.0054 16.2 0.1 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KND91782.1 - 0.0048 17.4 0.0 0.0081 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_60s PF00428.14 KND91782.1 - 0.094 13.1 1.3 0.17 12.3 0.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_S8 PF00082.17 KND91783.1 - 4.3e-43 147.4 12.7 4.3e-43 147.4 8.8 1.7 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KND91783.1 - 1.3e-15 57.7 0.1 2.5e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_2 PF00891.13 KND91784.1 - 1.6e-32 112.6 0.0 2.5e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KND91784.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 KND91784.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Glyco_hydro_2 PF00703.16 KND91787.1 - 3.1e-10 40.4 0.1 6.8e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KND91787.1 - 8e-07 28.7 0.1 1.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_31 PF01055.21 KND91788.1 - 3e-91 306.4 0.0 3.8e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KND91788.1 - 2.2e-14 53.0 0.5 6.8e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.11 KND91789.1 - 4.2e-29 101.3 31.3 4.2e-29 101.3 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CcmH PF03918.9 KND91789.1 - 0.11 11.4 0.1 0.73 8.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein EVC2_like PF12297.3 KND91789.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein NfeD PF01957.13 KND91789.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.3 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding NACHT PF05729.7 KND91791.1 - 0.021 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain zf-C2H2_4 PF13894.1 KND91791.1 - 0.022 15.0 18.6 0.071 13.4 0.1 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger KAP_NTPase PF07693.9 KND91791.1 - 0.051 12.5 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Metallophos PF00149.23 KND91792.1 - 5.7e-15 55.2 0.1 1.2e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SAP PF02037.22 KND91793.1 - 6.1e-14 51.1 0.3 1.2e-13 50.2 0.2 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KND91793.1 - 0.014 14.9 0.8 0.039 13.4 0.6 1.8 1 1 0 1 1 1 0 HeH/LEM domain CCER1 PF15482.1 KND91793.1 - 0.81 9.2 5.2 1.4 8.5 3.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 PTS_EIIC_2 PF13303.1 KND91794.1 - 1.2 7.8 3.3 1.7 7.3 2.3 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC MBOAT PF03062.14 KND91795.1 - 2.9e-36 125.2 12.4 2.9e-36 125.2 8.6 2.1 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferritin_2 PF13668.1 KND91796.1 - 5e-07 29.7 2.5 7.9e-07 29.0 1.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain Profilin PF00235.14 KND91796.1 - 0.12 12.4 0.3 0.32 11.1 0.1 1.6 2 0 0 2 2 2 0 Profilin DnaJ PF00226.26 KND91797.1 - 4.3e-22 77.6 2.2 1.7e-21 75.7 1.5 2.1 1 0 0 1 1 1 1 DnaJ domain SAPS PF04499.10 KND91797.1 - 1.2 7.7 3.8 2.2 6.7 2.6 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Metallophos PF00149.23 KND91798.1 - 2.8e-11 43.1 0.4 1e-10 41.3 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND91798.1 - 6.7e-07 29.2 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BiPBP_C PF06832.7 KND91798.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family PSDC PF12588.3 KND91799.1 - 6.8e-48 161.8 0.0 1.1e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase MFS_1 PF07690.11 KND91799.1 - 4.8e-41 140.6 52.2 5.1e-40 137.2 36.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PS_Dcarbxylase PF02666.10 KND91799.1 - 6.5e-17 61.5 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sugar_tr PF00083.19 KND91799.1 - 3e-14 52.4 28.6 2.1e-12 46.3 11.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Hemerythrin PF01814.18 KND91799.1 - 0.012 15.7 0.8 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF1488 PF07369.6 KND91800.1 - 0.085 12.7 0.7 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) Abhydrolase_6 PF12697.2 KND91801.1 - 4.8e-36 124.7 0.2 5.9e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND91801.1 - 6.5e-20 71.6 0.1 3.7e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND91801.1 - 9.5e-14 51.3 0.0 1.2e-12 47.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND91801.1 - 2.7e-09 36.7 0.0 9.4e-09 35.0 0.0 1.9 1 1 1 2 2 2 1 Putative lysophospholipase DUF1057 PF06342.7 KND91801.1 - 0.00061 18.6 0.0 0.0023 16.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 KND91801.1 - 0.00086 18.6 0.1 1.2 8.3 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase PF07224.6 KND91801.1 - 0.00089 18.1 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KND91801.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme EHN PF06441.7 KND91801.1 - 0.0067 16.3 0.1 0.044 13.7 0.0 2.3 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Peptidase_S9 PF00326.16 KND91801.1 - 0.029 13.6 0.1 0.35 10.0 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydro_lipase PF04083.11 KND91801.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NUDIX PF00293.23 KND91803.1 - 2.2e-13 50.0 0.3 3.9e-13 49.2 0.2 1.3 1 1 0 1 1 1 1 NUDIX domain p450 PF00067.17 KND91804.1 - 2e-51 175.0 0.0 3e-37 128.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 BTB PF00651.26 KND91805.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain Antifungal_pept PF11410.3 KND91806.1 - 5 7.3 9.5 7.3 6.7 1.1 2.3 2 0 0 2 2 2 0 Antifungal peptide Peptidase_C97 PF05903.9 KND91807.1 - 3.5e-06 26.8 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KND91807.1 - 0.02 14.8 0.3 0.1 12.5 0.2 2.0 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF4105 PF13387.1 KND91807.1 - 0.025 13.7 0.1 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) MFS_1 PF07690.11 KND91808.1 - 0.013 14.2 0.0 0.013 14.2 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DEAD PF00270.24 KND91810.1 - 1.2e-41 142.0 0.0 2.1e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KND91810.1 - 1.5e-22 78.9 0.4 2.7e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KND91810.1 - 2.9e-20 71.9 0.0 6.3e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pox_Ag35 PF03286.9 KND91810.1 - 0.71 9.3 5.1 1.2 8.6 3.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 KND91810.1 - 3.4 5.4 12.0 4.8 4.9 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KND91810.1 - 3.4 6.0 11.8 5 5.4 8.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 KND91810.1 - 4 7.4 10.6 6.5 6.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NMO PF03060.10 KND91813.1 - 4.5e-69 233.1 1.6 5.5e-69 232.8 1.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KND91813.1 - 7.4e-08 31.6 0.0 9.4e-05 21.4 0.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KND91813.1 - 3.2e-06 26.2 3.4 3.2e-06 26.2 2.3 1.7 1 1 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KND91813.1 - 0.092 11.6 0.2 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Sdh_cyt PF01127.17 KND91814.1 - 4.3e-17 62.0 3.0 6.4e-17 61.5 2.1 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.13 KND91815.1 - 2.1e-21 75.9 0.3 3.7e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91815.1 - 3.9e-09 36.2 8.1 6.8e-09 35.4 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 KND91816.1 - 5.6e-76 256.3 0.0 7.4e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ADH_zinc_N PF00107.21 KND91816.1 - 0.00022 20.7 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.8 KND91816.1 - 0.004 16.7 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DJ-1_PfpI PF01965.19 KND91817.1 - 2.5e-26 91.9 0.0 3.8e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KND91817.1 - 8.4e-13 47.6 0.0 1.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KND91817.1 - 0.0016 17.7 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KND91817.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KND91817.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 Opi1 PF08618.5 KND91818.1 - 1.5e-83 281.1 0.0 1e-68 232.2 0.0 3.1 1 1 1 2 2 2 2 Transcription factor Opi1 LVIVD PF08309.6 KND91819.1 - 0.00015 20.6 0.0 2.7 7.0 0.0 4.8 5 0 0 5 5 5 3 LVIVD repeat Beta_propel PF09826.4 KND91819.1 - 0.044 12.1 0.1 0.13 10.6 0.0 1.8 1 1 0 1 1 1 0 Beta propeller domain DUF1546 PF07571.8 KND91821.1 - 5.6e-27 93.7 0.0 1.2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KND91821.1 - 2.2e-21 75.5 0.4 3.7e-21 74.8 0.3 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KND91821.1 - 0.00028 20.9 0.5 0.00057 19.9 0.4 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KND91821.1 - 0.02 14.6 0.1 0.053 13.2 0.1 1.7 1 0 0 1 1 1 0 Bromodomain associated c-SKI_SMAD_bind PF08782.5 KND91823.1 - 0.11 12.6 0.6 7.4 6.7 0.1 2.5 2 0 0 2 2 2 0 c-SKI Smad4 binding domain MR_MLE_C PF13378.1 KND91824.1 - 5.3e-10 39.2 0.0 8.1e-09 35.4 0.0 2.2 1 1 1 2 2 2 1 Enolase C-terminal domain-like Sulfatase PF00884.18 KND91825.1 - 5.4e-22 78.3 0.3 1.2e-21 77.2 0.1 1.7 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KND91825.1 - 7.5e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KND91825.1 - 0.0067 14.8 0.0 0.0097 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Ribosomal_L34 PF00468.12 KND91826.1 - 4.2e-10 39.1 10.3 6.3e-10 38.5 7.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Glyco_hydro_3 PF00933.16 KND91827.1 - 1e-92 310.3 0.0 1.5e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND91827.1 - 1.3e-53 181.8 0.2 3e-52 177.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND91827.1 - 5.1e-21 74.4 0.5 9.4e-21 73.5 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4232 PF14016.1 KND91827.1 - 0.018 14.6 0.2 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) CARDB PF07705.6 KND91827.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 CARDB MFS_1 PF07690.11 KND91828.1 - 1.7e-31 109.2 29.2 2.4e-31 108.7 19.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KND91828.1 - 0.25 11.4 0.0 0.25 11.4 0.0 3.3 2 2 0 2 2 2 0 NfeD-like C-terminal, partner-binding NTF2 PF02136.15 KND91829.1 - 0.011 16.1 1.5 0.054 13.8 1.1 1.9 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KND91829.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.6 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.6 KND91830.1 - 9.5e-57 192.4 0.5 1.7e-56 191.5 0.4 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) GrpB PF04229.9 KND91830.1 - 1.5e-45 154.8 0.0 3e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 GrpB protein Acetyltransf_3 PF13302.1 KND91830.1 - 9.5e-23 80.9 0.0 6e-22 78.3 0.0 2.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.17 KND91830.1 - 3.4e-09 35.2 0.1 4.7e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Acetyltransf_1 PF00583.19 KND91830.1 - 2.8e-06 27.2 0.1 7.2e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KND91830.1 - 6.8e-05 22.7 0.3 0.032 14.1 0.1 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 KND91830.1 - 9.6e-05 21.6 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FR47 PF08445.5 KND91830.1 - 0.0006 19.5 0.2 0.27 11.0 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Anticodon_1 PF08264.8 KND91830.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA GOLD_2 PF13897.1 KND91830.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking AAA_18 PF13238.1 KND91831.1 - 1.1e-11 45.0 0.0 1.7e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND91831.1 - 3.6e-05 24.5 0.0 0.00016 22.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.15 KND91831.1 - 0.065 12.8 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Acetyltransf_1 PF00583.19 KND91832.1 - 0.046 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ParA PF10609.4 KND91835.1 - 3.8e-36 122.8 0.0 7.7e-36 121.8 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KND91835.1 - 7e-14 51.6 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KND91835.1 - 1.5e-06 27.4 0.1 0.0001 21.5 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 KND91835.1 - 3.9e-05 22.8 0.4 0.00027 20.0 0.2 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 KND91835.1 - 8e-05 22.6 0.1 0.00028 20.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 KND91835.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 KND91835.1 - 0.0018 17.7 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KND91835.1 - 0.0024 16.6 0.6 0.0039 16.0 0.4 1.2 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.1 KND91835.1 - 0.0078 15.8 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KND91835.1 - 0.051 12.7 0.9 0.11 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 KND91835.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KND91835.1 - 0.2 10.7 0.1 0.54 9.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF4131 PF13567.1 KND91836.1 - 0.085 12.2 6.3 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NOB1_Zn_bind PF08772.6 KND91837.1 - 8.4e-32 108.8 2.0 1.5e-31 107.9 1.4 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KND91837.1 - 0.0007 19.4 8.0 0.0024 17.7 5.6 2.0 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator RRP7 PF12923.2 KND91837.1 - 0.022 14.7 0.6 0.022 14.7 0.4 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) UPF0278 PF08745.6 KND91837.1 - 0.12 11.6 0.1 11 5.2 0.0 2.4 2 1 0 2 2 2 0 UPF0278 family zf-NADH-PPase PF09297.6 KND91837.1 - 0.33 10.4 5.8 0.09 12.3 0.7 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RR_TM4-6 PF06459.7 KND91837.1 - 0.82 9.5 6.7 1.2 8.9 4.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAM_decarbox PF01536.11 KND91838.1 - 1.6e-84 283.4 0.0 1.9e-82 276.5 0.0 2.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Aa_trans PF01490.13 KND91839.1 - 2.6e-56 190.8 33.2 3e-56 190.6 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Zn_clus PF00172.13 KND91841.1 - 2.1e-17 62.7 27.2 9.1e-09 35.0 6.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND91841.1 - 2e-10 39.9 0.5 3.3e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain cobW PF02492.14 KND91842.1 - 2.4e-42 144.3 2.4 3.6e-42 143.8 1.6 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KND91842.1 - 8.7e-18 63.8 0.1 3.2e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 KND91842.1 - 0.0022 17.7 0.1 0.0043 16.7 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KND91842.1 - 0.0065 16.0 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Gasdermin PF04598.7 KND91842.1 - 0.0082 14.9 0.4 0.013 14.2 0.3 1.3 1 0 0 1 1 1 1 Gasdermin family CbiA PF01656.18 KND91842.1 - 0.009 15.4 0.8 0.017 14.5 0.5 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 KND91842.1 - 0.028 14.5 0.1 0.075 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND91842.1 - 0.032 14.1 0.0 0.081 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KND91842.1 - 0.034 13.7 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KND91842.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 KND91842.1 - 0.041 12.6 0.5 3.1 6.4 0.1 2.3 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 KND91842.1 - 0.05 13.5 1.9 0.16 11.9 0.8 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KND91842.1 - 0.063 12.7 0.2 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 KND91842.1 - 0.072 12.6 0.1 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KND91842.1 - 0.1 12.2 0.1 0.33 10.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Hexapep PF00132.19 KND91843.1 - 6.5e-16 57.0 10.1 1.2e-10 40.3 1.2 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KND91843.1 - 2.5e-11 42.9 13.0 1.4e-09 37.3 0.9 3.9 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KND91843.1 - 0.00031 20.7 0.0 0.00075 19.4 0.0 1.7 1 1 0 1 1 1 1 Maltose acetyltransferase SOR PF07682.6 KND91843.1 - 0.14 10.6 0.0 0.35 9.4 0.0 1.6 2 0 0 2 2 2 0 Sulphur oxygenase reductase Fungal_trans_2 PF11951.3 KND91844.1 - 6.5e-19 67.7 0.5 1e-18 67.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.7 KND91844.1 - 0.071 13.6 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain QCR10 PF09796.4 KND91846.1 - 2.5e-19 68.6 0.1 3.6e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 KND91846.1 - 0.0051 16.5 0.1 0.013 15.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DIE2_ALG10 PF04922.7 KND91847.1 - 8e-77 258.8 22.4 5.2e-58 196.8 4.5 3.2 3 0 0 3 3 3 3 DIE2/ALG10 family Sas10_Utp3 PF04000.10 KND91849.1 - 1.4e-16 60.4 1.6 3.6e-16 59.1 1.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family WEMBL PF05701.6 KND91851.1 - 0.001 17.6 12.5 0.0018 16.8 8.7 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF4201 PF13870.1 KND91851.1 - 0.016 14.6 20.7 0.019 14.4 12.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DHQ_synthase PF01761.15 KND91851.1 - 0.096 11.5 0.4 0.16 10.9 0.3 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase V_ATPase_I PF01496.14 KND91851.1 - 0.71 7.6 7.0 1.1 7.0 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 KND91851.1 - 1 8.8 16.8 0.099 12.1 7.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF745) IPP-2 PF04979.9 KND91852.1 - 4.8e-11 43.0 8.6 9.1e-06 25.9 0.7 2.2 1 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Zn_clus PF00172.13 KND91853.1 - 2.9e-14 52.6 24.5 3.2e-07 30.1 5.3 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND91853.1 - 5.2e-13 48.4 0.0 9.2e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 KND91855.1 - 5.7e-05 22.9 0.2 6.4e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND91855.1 - 0.0017 17.4 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3018 PF11455.3 KND91855.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) APH PF01636.18 KND91856.1 - 1.7e-15 57.4 0.0 3.5e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KND91856.1 - 0.0012 17.5 0.0 0.25 9.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 KND91856.1 - 0.0053 16.3 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 KND91856.1 - 0.032 13.2 0.0 3.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_4 PF01565.18 KND91860.1 - 7.7e-18 64.3 1.2 1.7e-17 63.2 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND91860.1 - 7e-06 25.8 0.1 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FACT-Spt16_Nlob PF14826.1 KND91861.1 - 1.7e-15 56.9 0.1 1.7e-12 47.1 0.0 3.2 2 1 0 2 2 2 2 FACT complex subunit SPT16 N-terminal lobe domain DPPIV_N PF00930.16 KND91862.1 - 7.7e-98 327.3 0.1 1.1e-97 326.8 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KND91862.1 - 1.2e-37 129.1 1.1 2.2e-37 128.3 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND91862.1 - 9.7e-05 22.1 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 KND91863.1 - 4.9e-09 35.9 6.1 7.9e-09 35.2 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 KND91864.1 - 2.8e-70 237.4 7.9 4.2e-70 236.8 5.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family tRNA_SAD PF07973.9 KND91865.1 - 7.6e-07 28.9 1.1 1.3e-06 28.1 0.8 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 KND91865.1 - 2.4e-06 26.1 0.2 3e-06 25.8 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Peptidase_S10 PF00450.17 KND91866.1 - 6.6e-80 269.3 0.1 8.5e-80 268.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Tr-sialidase_C PF11052.3 KND91866.1 - 0.0082 15.9 4.4 0.04 13.8 2.2 2.6 2 0 0 2 2 2 1 Trans-sialidase of Trypanosoma hydrophobic C-terminal Phospholip_A2_3 PF09056.6 KND91867.1 - 4e-44 149.3 0.8 7.2e-44 148.5 0.6 1.4 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Phage_T7_Capsid PF05396.6 KND91867.1 - 0.09 12.9 0.7 0.16 12.0 0.5 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein CN_hydrolase PF00795.17 KND91868.1 - 1.3e-23 83.3 0.0 5.1e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DUF899 PF05988.7 KND91869.1 - 1.2e-74 250.3 0.0 1.3e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 KND91869.1 - 0.005 16.5 0.0 0.0087 15.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family zf-C2H2 PF00096.21 KND91870.1 - 8.5e-09 35.2 17.4 0.077 13.3 0.9 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND91870.1 - 1e-07 31.7 17.1 0.094 13.0 0.6 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 KND91870.1 - 3.3e-07 30.2 9.5 0.0055 16.8 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND91870.1 - 3.8e-07 30.0 6.1 0.006 16.6 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND91870.1 - 1.3e-05 24.9 4.0 0.025 14.4 0.0 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KND91870.1 - 0.00032 20.7 10.7 0.021 14.9 0.9 3.1 2 2 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KND91870.1 - 0.00044 20.3 22.3 0.0024 18.1 0.2 5.2 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_2 PF12756.2 KND91870.1 - 0.00096 19.2 8.8 0.013 15.6 0.4 4.0 2 2 2 4 4 4 1 C2H2 type zinc-finger (2 copies) Ribosomal_L34e PF01199.13 KND91870.1 - 0.0017 18.5 0.9 5.2 7.3 0.0 3.6 2 1 0 3 3 3 1 Ribosomal protein L34e DZR PF12773.2 KND91870.1 - 0.0036 17.0 5.1 0.11 12.3 0.3 3.3 3 0 0 3 3 3 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 KND91870.1 - 0.022 14.7 5.9 7 6.6 0.1 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zf-BED PF02892.10 KND91870.1 - 0.062 13.0 0.4 0.062 13.0 0.3 3.1 3 1 0 3 3 2 0 BED zinc finger zf-RING_3 PF14369.1 KND91870.1 - 0.29 11.1 6.7 5.7 7.0 0.1 3.9 4 0 0 4 4 4 0 zinc-finger Elf1 PF05129.8 KND91870.1 - 0.3 10.8 7.7 3.7 7.3 0.4 3.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DUF164 PF02591.10 KND91870.1 - 0.34 10.7 2.3 23 4.8 0.0 3.4 3 0 0 3 3 3 0 Putative zinc ribbon domain IBR PF01485.16 KND91870.1 - 0.84 9.5 8.7 1.3 8.9 0.2 3.6 2 1 0 3 3 3 0 IBR domain zf-RING_5 PF14634.1 KND91870.1 - 0.9 9.3 13.0 1.7 8.4 3.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Rep_fac-A_C PF08646.5 KND91870.1 - 2 8.1 4.2 11 5.7 0.1 2.6 3 0 0 3 3 3 0 Replication factor-A C terminal domain CpXC PF14353.1 KND91870.1 - 8 6.4 6.0 56 3.7 0.1 2.9 2 1 0 2 2 2 0 CpXC protein Peptidase_S8 PF00082.17 KND91871.1 - 1.2e-21 77.1 0.0 1.7e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family B56 PF01603.15 KND91872.1 - 1.5e-170 567.2 1.8 1.9e-170 566.9 1.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 KND91872.1 - 0.01 15.2 0.7 1.5 8.2 0.1 2.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TRAPP PF04051.11 KND91874.1 - 2.1e-37 128.0 0.0 2.6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component REV PF00424.13 KND91874.1 - 0.47 10.3 3.4 1.9 8.4 0.1 2.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) BCS1_N PF08740.6 KND91875.1 - 4.6e-42 143.7 1.0 4.6e-42 143.7 0.7 2.0 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 KND91875.1 - 7.4e-18 65.0 0.0 3.7e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND91875.1 - 0.00014 22.6 0.4 0.00054 20.7 0.2 2.2 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KND91875.1 - 0.00016 21.3 0.3 0.00032 20.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND91875.1 - 0.00045 19.3 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KND91875.1 - 0.0027 17.1 0.1 0.014 14.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KND91875.1 - 0.022 14.6 0.1 0.073 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain TFIIF_alpha PF05793.7 KND91875.1 - 0.044 12.1 29.3 0.069 11.5 20.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) KaiC PF06745.8 KND91875.1 - 0.058 12.4 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 KaiC SPX PF03105.14 KND91875.1 - 0.065 13.0 14.7 0.11 12.2 10.2 1.3 1 0 0 1 1 1 0 SPX domain SAPS PF04499.10 KND91875.1 - 0.14 10.7 7.9 0.19 10.3 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.6 KND91875.1 - 0.17 11.6 10.2 0.29 10.9 7.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2201_N PF13203.1 KND91875.1 - 0.39 9.8 16.8 0.022 13.9 8.0 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain Ycf1 PF05758.7 KND91875.1 - 0.39 8.3 6.2 0.56 7.8 4.3 1.2 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 KND91875.1 - 0.53 9.2 1.7 0.79 8.6 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_16 PF13191.1 KND91875.1 - 0.54 10.2 4.1 1.2 9.1 0.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain Nop14 PF04147.7 KND91875.1 - 0.67 7.8 24.0 0.95 7.3 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.7 KND91875.1 - 1.2 6.8 6.9 1.7 6.3 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sigma70_ner PF04546.8 KND91875.1 - 4.4 6.8 18.2 9.1 5.8 12.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CSF-1 PF05337.6 KND91877.1 - 0.045 13.0 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Glyco_transf_17 PF04724.8 KND91878.1 - 2.1e-48 165.1 0.1 3.2e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 ACT_3 PF10000.4 KND91879.1 - 0.079 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 ACT domain ABC_membrane PF00664.18 KND91880.1 - 2.9e-15 56.4 7.5 2.9e-15 56.4 5.2 3.5 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND91880.1 - 1.6e-12 47.9 0.1 4.2e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KND91880.1 - 0.0016 17.7 0.1 0.17 11.0 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KND91880.1 - 0.065 12.6 1.0 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KND91880.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.1 KND91880.1 - 0.28 11.1 0.0 2.3 8.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KND91881.1 - 7.9e-08 32.0 9.6 1.3e-07 31.4 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND91881.1 - 2e-06 26.8 0.0 3.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.1 KND91882.1 - 1.8e-17 64.4 0.0 4.6e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KND91882.1 - 4.9e-13 48.7 0.0 7.5e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KND91882.1 - 0.00018 21.5 0.4 0.00037 20.5 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 KND91882.1 - 0.00019 21.1 0.0 0.00095 18.9 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 KND91882.1 - 0.0073 16.6 0.1 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KND91882.1 - 0.051 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cupin_2 PF07883.6 KND91883.1 - 8.3e-10 38.0 0.1 1.4e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain TPR_11 PF13414.1 KND91884.1 - 7.9e-20 70.2 4.7 8.7e-15 54.1 0.0 2.7 2 1 1 3 3 2 2 TPR repeat U-box PF04564.10 KND91884.1 - 6.3e-18 64.5 0.0 1.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.12 KND91884.1 - 1.1e-09 37.4 3.2 0.063 13.2 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND91884.1 - 1.3e-08 34.1 2.6 0.0018 17.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND91884.1 - 5.9e-08 32.3 5.3 0.00015 21.7 1.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND91884.1 - 9.6e-07 29.0 3.0 0.0013 19.0 0.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND91884.1 - 7.7e-06 26.0 3.0 0.14 12.9 0.7 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND91884.1 - 1.7e-05 25.3 4.6 0.004 17.7 0.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND91884.1 - 0.00057 19.7 3.6 0.012 15.5 1.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KND91884.1 - 0.0034 17.4 0.4 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KND91884.1 - 0.0038 17.3 0.4 0.0089 16.1 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KND91884.1 - 0.0093 15.8 1.2 0.054 13.3 0.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KND91884.1 - 0.042 13.7 0.8 1.3 8.9 0.2 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KND91884.1 - 0.099 12.4 0.6 11 6.0 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND91884.1 - 0.12 12.9 3.0 0.35 11.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND91884.1 - 0.93 10.1 4.3 2.2 8.9 1.3 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.7 KND91885.1 - 0.76 8.3 4.2 0.88 8.0 2.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pol_alpha_B_N PF08418.5 KND91885.1 - 6.3 6.2 8.9 7.7 5.9 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SET PF00856.23 KND91886.1 - 3.3e-18 66.5 0.9 3.3e-18 66.5 0.6 3.2 3 1 0 3 3 3 1 SET domain AMP-binding PF00501.23 KND91887.1 - 1.4e-272 903.2 0.0 2.5e-86 289.7 0.1 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KND91887.1 - 3.4e-162 538.3 0.0 2.8e-42 144.6 0.0 6.6 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KND91887.1 - 6.1e-45 151.3 8.3 2.3e-11 43.7 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KND91887.1 - 6.2e-22 78.3 2.8 6.9e-06 26.9 0.1 5.6 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KND91887.1 - 0.0068 14.9 0.0 0.51 8.7 0.0 3.2 4 0 0 4 4 4 1 GH3 auxin-responsive promoter MRP-L51 PF10244.4 KND91887.1 - 0.17 11.8 0.0 37 4.4 0.0 3.5 4 0 0 4 4 4 0 Mitochondrial ribosomal subunit PARP_regulatory PF01358.13 KND91887.1 - 8.3 4.9 0.0 15 4.1 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit His_Phos_1 PF00300.17 KND91888.1 - 2.2e-28 99.3 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF566 PF04484.7 KND91889.1 - 0.53 9.7 6.3 0.64 9.4 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Zn_clus PF00172.13 KND91890.1 - 2.5e-08 33.7 8.3 3.7e-08 33.1 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KND91891.1 - 6.3e-15 55.2 0.0 8.2e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91891.1 - 9.5e-13 48.7 0.0 1.5e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91891.1 - 8.7e-11 42.1 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND91891.1 - 9.4e-11 41.5 0.0 2.3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND91891.1 - 1.9e-10 41.1 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND91891.1 - 2.4e-09 36.6 0.0 3.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KND91891.1 - 1e-08 35.4 0.1 3e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND91891.1 - 1.5e-06 28.2 0.3 3.7e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND91891.1 - 0.0029 16.9 0.0 0.0056 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KND91891.1 - 0.0033 17.0 0.1 0.0063 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND91891.1 - 0.077 12.0 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.6 KND91891.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RRM_6 PF14259.1 KND91892.1 - 2.6e-08 33.7 0.1 5.6e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND91892.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRAL_TRIO PF00650.15 KND91893.1 - 1.9e-14 53.4 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND91893.1 - 0.009 16.1 0.0 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.1 KND91893.1 - 0.068 12.8 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic Ubiquitin UCH PF00443.24 KND91894.1 - 6.9e-54 182.7 0.0 8.5e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND91894.1 - 2.7e-19 69.7 0.4 1.6e-18 67.1 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KND91894.1 - 2.5e-10 39.5 0.1 4.8e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KND91894.1 - 0.028 14.0 0.1 0.067 12.8 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3568 PF12092.3 KND91894.1 - 0.14 11.8 1.5 0.57 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3568) ARPC4 PF05856.7 KND91895.1 - 1.2e-75 252.5 3.2 1.3e-75 252.4 2.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ALG3 PF05208.8 KND91896.1 - 9.2e-143 475.9 17.3 1.1e-142 475.7 12.0 1.0 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.19 KND91897.1 - 8.3e-29 100.5 0.2 1.3e-28 99.9 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND91897.1 - 0.015 15.3 0.4 0.039 13.9 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND91897.1 - 0.037 12.8 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KND91897.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND91897.1 - 0.44 9.5 1.9 0.46 9.5 0.1 2.0 3 0 0 3 3 3 0 Thi4 family MFS_1 PF07690.11 KND91898.1 - 1.8e-19 69.7 83.1 1.3e-14 53.6 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TAT_signal PF10518.4 KND91898.1 - 0.019 14.9 2.2 0.019 14.9 1.5 3.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence HAD PF12710.2 KND91899.1 - 1.1e-14 55.0 0.1 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND91899.1 - 4.6e-05 23.6 0.0 0.00023 21.4 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KND91899.1 - 0.00029 20.2 0.0 0.00073 18.9 0.0 1.6 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 KND91899.1 - 0.0047 16.1 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 KND91899.1 - 0.0064 16.9 0.9 0.069 13.5 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase CHAT PF12770.2 KND91901.1 - 7.7e-09 35.0 0.1 3e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 CHAT domain She9_MDM33 PF05546.6 KND91902.1 - 9.5e-81 270.3 4.4 1.3e-80 269.8 3.0 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family BCAS2 PF05700.6 KND91902.1 - 0.034 13.5 0.8 0.06 12.7 0.5 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF4398 PF14346.1 KND91902.1 - 1.7 8.7 9.0 0.1 12.6 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) Acyl-CoA_dh_1 PF00441.19 KND91903.1 - 2.5e-41 141.2 4.0 4.4e-41 140.4 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND91903.1 - 7.1e-29 100.6 1.0 4.3e-28 98.1 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KND91903.1 - 4.9e-17 62.4 2.0 1e-16 61.4 1.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KND91903.1 - 2.1e-14 52.7 0.1 4.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HR1 PF02185.11 KND91904.1 - 1.1e-24 85.9 12.7 1e-16 60.4 2.5 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KND91904.1 - 7.7e-19 67.1 32.3 2.5e-11 43.0 7.8 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KND91904.1 - 2.5 8.0 15.0 2.9 7.8 2.7 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4206 PF13901.1 KND91904.1 - 6.2 6.3 19.9 1.3 8.5 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Fungal_trans PF04082.13 KND91905.1 - 0.0042 15.9 0.3 0.0069 15.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91906.1 - 0.00038 20.3 6.9 0.00086 19.1 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND91906.1 - 0.0057 15.5 0.3 0.0093 14.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KND91907.1 - 1.6e-23 83.4 0.3 3e-23 82.5 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KND91907.1 - 1e-08 34.9 0.1 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KND91907.1 - 0.0044 15.4 0.0 0.0066 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 KND91907.1 - 0.028 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Zn_clus PF00172.13 KND91908.1 - 1.9e-08 34.0 11.8 2.8e-08 33.5 8.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND91908.1 - 0.00061 18.5 0.4 0.0012 17.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polyketide_cyc2 PF10604.4 KND91909.1 - 2.5e-07 30.9 0.0 2.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.11 KND91910.1 - 1.4e-27 96.3 22.8 1.4e-27 96.3 15.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_trans PF01144.18 KND91911.1 - 1.3e-92 308.8 0.3 1.3e-53 181.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KND91911.1 - 0.0013 18.4 0.1 0.0066 16.1 0.1 1.9 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain N2227 PF07942.7 KND91912.1 - 3.8e-96 321.2 0.0 5.1e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KND91912.1 - 5.6e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND91912.1 - 0.002 18.5 0.0 0.0081 16.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91912.1 - 0.037 14.6 0.0 0.33 11.5 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KND91912.1 - 0.063 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KND91913.1 - 9.8e-26 90.6 3.8 1.4e-25 90.1 2.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND91913.1 - 4.6e-23 82.2 0.0 6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND91913.1 - 6e-13 48.8 1.1 1.1e-12 48.0 0.8 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KND91913.1 - 0.37 10.6 3.1 0.49 10.2 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HEAT_EZ PF13513.1 KND91915.1 - 1.1e-30 105.2 9.0 1.7e-14 53.8 0.0 11.0 8 2 5 13 13 13 5 HEAT-like repeat HEAT PF02985.17 KND91915.1 - 2.7e-24 82.9 8.2 0.00047 20.0 0.0 10.4 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.1 KND91915.1 - 1.2e-20 73.6 0.4 8.6e-07 29.1 0.0 7.9 5 3 5 10 10 10 6 HEAT repeats MMS19_C PF12460.3 KND91915.1 - 9.3e-10 37.7 0.5 0.036 12.8 0.0 4.9 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 KND91915.1 - 5.6e-09 36.0 0.8 0.54 10.0 0.0 6.0 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KND91915.1 - 9.5e-08 32.3 0.0 0.025 14.9 0.0 5.8 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KND91915.1 - 1.1e-07 31.6 0.7 2e-06 27.6 0.1 3.5 2 1 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KND91915.1 - 6e-05 22.5 0.0 16 4.7 0.0 5.7 3 2 2 5 5 5 0 CLASP N terminal Arm PF00514.18 KND91915.1 - 0.00062 19.5 3.4 0.99 9.3 0.0 6.3 9 0 0 9 9 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KND91915.1 - 0.02 14.5 0.5 14 5.3 0.0 4.4 3 1 2 5 5 5 0 rRNA processing/ribosome biogenesis DUF3437 PF11919.3 KND91915.1 - 0.076 12.7 0.1 6.1 6.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) HEAT_PBS PF03130.11 KND91915.1 - 0.18 12.3 5.8 5.5 7.7 0.0 5.0 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat OPT PF03169.10 KND91917.1 - 9.3e-176 585.9 61.5 1.1e-175 585.7 42.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 KND91917.1 - 0.093 11.8 3.7 0.38 9.8 2.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3129 PF11327.3 KND91918.1 - 3.9e-68 228.8 13.3 5.5e-68 228.4 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Fungal_trans_2 PF11951.3 KND91919.1 - 8e-23 80.6 0.0 3.8e-22 78.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KND91920.1 - 1.6e-35 122.5 52.6 1.8e-35 122.3 35.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MAP7 PF05672.6 KND91921.1 - 0.00016 21.1 35.9 0.00025 20.4 24.9 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family ARGLU PF15346.1 KND91921.1 - 0.023 14.4 34.6 0.036 13.8 24.0 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 eIF-3_zeta PF05091.7 KND91921.1 - 0.024 13.2 5.3 0.033 12.8 3.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Caldesmon PF02029.10 KND91921.1 - 0.95 7.8 29.2 1.4 7.2 20.2 1.1 1 0 0 1 1 1 0 Caldesmon NARP1 PF12569.3 KND91921.1 - 2 7.0 13.1 3 6.4 9.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1682 PF07946.9 KND91921.1 - 2.1 7.1 19.4 3.3 6.4 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GAGA_bind PF06217.7 KND91921.1 - 3 7.7 7.9 5 7.0 5.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 KND91921.1 - 3.7 6.8 13.5 6.5 6.0 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KND91921.1 - 5.1 6.8 9.3 8.1 6.1 6.4 1.2 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 KND91921.1 - 5.5 6.3 34.7 9.8 5.4 24.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal KilA-N PF04383.8 KND91922.1 - 0.017 14.7 1.5 0.095 12.3 0.0 2.7 2 1 0 2 2 2 0 KilA-N domain DUF2201_N PF13203.1 KND91922.1 - 0.038 13.1 6.5 0.039 13.1 2.2 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF2146 PF10220.4 KND91922.1 - 0.4 8.6 9.4 0.61 8.0 6.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) HSP70 PF00012.15 KND91922.1 - 0.82 7.4 14.5 1.1 7.0 10.0 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4604 PF15377.1 KND91922.1 - 6.2 7.0 30.6 0.13 12.4 13.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Rho_GDI PF02115.12 KND91923.1 - 1.4e-56 191.0 0.3 1.5e-56 190.9 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Syndecan PF01034.15 KND91923.1 - 0.79 9.4 2.7 5.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain Metallophos PF00149.23 KND91924.1 - 3.5e-42 144.0 0.7 4.3e-42 143.7 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 KND91925.1 - 5.2e-05 22.9 1.5 0.00014 21.6 1.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 KND91925.1 - 0.035 13.7 0.5 0.14 11.8 0.3 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KND91925.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Hex_IIIa PF02455.11 KND91926.1 - 1.8 7.1 7.9 3.3 6.2 5.5 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CcoS PF03597.10 KND91927.1 - 1.3 8.5 4.6 2.5 7.6 3.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Exo_endo_phos PF03372.18 KND91929.1 - 4.7e-09 36.5 0.0 5.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KND91929.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TPR_12 PF13424.1 KND91932.1 - 9.2e-22 76.7 15.7 1.7e-12 47.1 0.4 5.8 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 KND91932.1 - 8.5e-13 47.7 12.4 8.5e-05 22.3 0.0 6.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KND91932.1 - 7.1e-07 28.7 6.8 0.0027 17.2 0.0 4.1 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 KND91932.1 - 2.1e-06 27.1 10.6 0.092 12.5 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND91932.1 - 2.3e-06 26.9 2.3 0.022 14.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND91932.1 - 5e-05 23.8 14.7 0.11 13.2 0.1 5.3 4 2 2 6 6 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 KND91932.1 - 0.00011 22.3 0.1 0.007 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 KND91932.1 - 0.00047 19.8 15.2 0.18 11.7 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KND91932.1 - 0.0012 18.7 0.6 0.0036 17.2 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KND91932.1 - 0.0017 18.3 1.5 0.0079 16.1 0.0 2.9 4 0 0 4 4 4 1 AAA ATPase domain Apc3 PF12895.2 KND91932.1 - 0.0025 17.9 0.3 1.7 8.8 0.0 3.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4477 PF14780.1 KND91932.1 - 0.012 15.0 0.0 10 5.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4477) TPR_8 PF13181.1 KND91932.1 - 0.018 14.7 0.1 16 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 KND91932.1 - 0.023 14.4 0.0 0.06 13.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KND91932.1 - 0.14 11.3 0.0 0.42 9.8 0.0 1.7 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPR_14 PF13428.1 KND91932.1 - 0.74 10.6 13.0 9 7.2 0.0 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat PaaX_C PF08223.6 KND91933.1 - 0.18 11.4 3.8 7.8 6.1 0.1 2.3 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain SPRY PF00622.23 KND91934.1 - 8e-19 67.9 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain AMP-binding PF00501.23 KND91935.1 - 2.1e-30 105.4 0.0 2.6e-29 101.8 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KND91935.1 - 2.5e-28 98.6 0.0 3.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KND91935.1 - 1.1e-12 47.8 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KND91935.1 - 1.9e-09 37.6 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KND91935.1 - 0.0069 16.3 1.9 0.011 15.6 0.3 2.2 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KND91935.1 - 0.012 14.5 0.0 0.33 9.8 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KND91935.1 - 0.15 10.9 0.0 0.65 8.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_23 PF13489.1 KND91937.1 - 1.4e-21 76.9 0.0 2.8e-21 75.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND91937.1 - 8.6e-13 48.8 0.1 1.3e-11 45.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND91937.1 - 1e-12 47.8 0.0 8.8e-12 44.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND91937.1 - 2.2e-12 47.2 0.0 3.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND91937.1 - 1.5e-10 41.4 0.0 1.1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND91937.1 - 2.7e-06 26.5 0.0 3.1e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KND91937.1 - 3.6e-06 27.2 0.0 1e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND91937.1 - 4.5e-05 22.7 0.0 6.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KND91937.1 - 0.00015 21.7 0.0 0.0018 18.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KND91937.1 - 0.00032 20.7 0.0 0.0007 19.6 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 KND91937.1 - 0.00044 19.6 0.0 0.0024 17.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KND91937.1 - 0.00091 18.3 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KND91937.1 - 0.0011 18.1 0.0 0.0023 17.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KND91937.1 - 0.026 14.0 0.0 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase HD PF01966.17 KND91940.1 - 2.4e-05 24.3 0.0 4.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 HD domain Mito_fiss_reg PF05308.6 KND91941.1 - 5.6 6.2 16.4 0.8 9.0 5.7 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_hydro_30 PF02055.11 KND91942.1 - 5.6e-48 163.3 0.1 7.3e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KND91942.1 - 0.00033 19.7 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF3050 PF11251.3 KND91942.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Abhydrolase_6 PF12697.2 KND91943.1 - 3.1e-24 86.1 10.1 3.7e-24 85.8 7.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND91943.1 - 5.9e-12 45.5 4.1 1e-11 44.7 2.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND91943.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cellulase PF00150.13 KND91943.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Abhydrolase_1 PF00561.15 KND91943.1 - 0.12 11.9 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND91943.1 - 0.41 9.8 3.1 0.83 8.8 0.2 2.5 3 1 1 4 4 4 0 Prolyl oligopeptidase family BAR PF03114.13 KND91944.1 - 4.7e-45 153.8 4.7 5.6e-45 153.6 3.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KND91944.1 - 3.3e-06 26.2 1.8 4.4e-06 25.8 1.2 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Cyclin_N PF00134.18 KND91945.1 - 0.056 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Fungal_trans PF04082.13 KND91946.1 - 9.7e-06 24.6 0.1 1.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain eIF-1a PF01176.14 KND91947.1 - 2.8e-13 49.0 0.0 3.8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sugar_tr PF00083.19 KND91948.1 - 8.9e-36 123.4 10.0 1.1e-35 123.1 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND91948.1 - 4e-09 35.6 16.3 6e-09 35.0 11.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Romo1 PF10247.4 KND91948.1 - 0.032 14.4 0.9 0.092 12.9 0.7 1.8 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Na_Ca_ex PF01699.19 KND91949.1 - 4.8e-09 35.9 3.5 9.3e-09 35.0 2.4 1.4 1 0 0 1 1 1 1 Sodium/calcium exchanger protein NUMOD3 PF07460.6 KND91950.1 - 0.0071 16.2 0.1 0.0071 16.2 0.1 2.0 2 0 0 2 2 2 1 NUMOD3 motif (2 copies) PTS_IIA PF02255.11 KND91950.1 - 4.9 7.1 8.2 1.9 8.4 0.7 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit HSP90 PF00183.13 KND91952.1 - 8.3e-229 760.3 35.6 2.4e-215 715.9 19.1 3.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.21 KND91952.1 - 5.8e-12 45.3 0.1 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KND91952.1 - 1.1e-10 41.3 0.3 1.1e-10 41.3 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KND91952.1 - 0.0086 16.3 5.5 0.013 15.7 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1676) PVL_ORF50 PF07768.6 KND91952.1 - 0.33 10.9 16.7 0.09 12.7 5.3 2.8 2 0 0 2 2 2 0 PVL ORF-50-like family LOH1CR12 PF10158.4 KND91952.1 - 0.33 10.7 5.0 0.066 12.9 0.3 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Glyco_hydro_77 PF02446.12 KND91952.1 - 0.47 8.9 8.7 2.4 6.6 0.1 2.4 2 0 0 2 2 2 0 4-alpha-glucanotransferase GAGA_bind PF06217.7 KND91952.1 - 7.9 6.3 9.2 0.33 10.8 1.6 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Flavin_Reduct PF01613.13 KND91954.1 - 3e-35 121.3 0.0 3.4e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Vps5 PF09325.5 KND91955.1 - 3.7e-87 291.5 4.8 5.5e-87 290.9 3.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KND91955.1 - 2.3e-23 82.1 0.0 5.3e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 KND91955.1 - 0.0061 15.5 2.0 0.011 14.7 1.4 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking His_Phos_2 PF00328.17 KND91955.1 - 0.05 12.9 1.6 0.083 12.2 1.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BAR PF03114.13 KND91955.1 - 0.28 10.6 7.9 0.49 9.8 5.5 1.4 1 1 0 1 1 1 0 BAR domain WD40 PF00400.27 KND91956.1 - 7.6e-45 149.2 16.4 6.4e-07 29.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KND91956.1 - 1.8e-22 79.9 0.1 2.7e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 WD40 associated region in TFIID subunit eIF2A PF08662.6 KND91956.1 - 0.00048 19.9 0.0 0.0076 15.9 0.0 2.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KND91956.1 - 0.00077 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 KND91956.1 - 0.026 13.2 0.0 6.5 5.3 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 KND91956.1 - 0.11 10.5 0.3 4.6 5.2 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Med11 PF10280.4 KND91957.1 - 3.6e-30 104.4 0.0 4.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Ytp1 PF10355.4 KND91958.1 - 9.7e-83 277.4 16.2 2e-82 276.4 11.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KND91958.1 - 5.5e-30 103.0 0.3 5.5e-30 103.0 0.2 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) DUF897 PF05982.7 KND91958.1 - 3.4 6.3 8.8 0.59 8.8 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF897) CBM_2 PF00553.14 KND91959.1 - 0.064 13.3 1.6 0.11 12.6 1.1 1.3 1 0 0 1 1 1 0 Cellulose binding domain PhyH PF05721.8 KND91960.1 - 5.8e-20 72.2 0.0 9.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-DHHC PF01529.15 KND91962.1 - 6e-44 149.5 1.0 1.1e-43 148.6 0.7 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 KND91962.1 - 0.097 12.5 6.6 0.18 11.6 4.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon SH PF01445.12 KND91962.1 - 0.98 9.1 3.7 0.35 10.5 0.4 1.9 2 0 0 2 2 2 0 Viral small hydrophobic protein PI-PLC-X PF00388.14 KND91963.1 - 5.1e-60 201.1 0.0 8.6e-60 200.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KND91963.1 - 8.6e-37 125.7 0.0 2.3e-36 124.3 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KND91963.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 KND91963.1 - 0.00047 20.1 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 KND91963.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family YSIRK_signal PF04650.12 KND91964.1 - 0.53 9.8 0.0 0.53 9.8 0.0 2.3 3 0 0 3 3 3 0 YSIRK type signal peptide Zw10 PF06248.8 KND91965.1 - 5.9e-12 44.5 1.0 9.1e-05 20.8 1.6 2.4 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 MutS_III PF05192.13 KND91965.1 - 0.026 14.2 0.8 0.1 12.3 0.4 2.2 1 1 0 1 1 1 0 MutS domain III Mss4 PF04421.8 KND91965.1 - 0.041 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Mss4 protein SRA1 PF07304.6 KND91965.1 - 0.042 13.5 3.5 0.054 13.2 0.7 2.3 2 1 1 3 3 3 0 Steroid receptor RNA activator (SRA1) CorA PF01544.13 KND91965.1 - 0.32 9.9 4.2 0.52 9.2 2.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.6 KND91965.1 - 1.8 8.4 6.6 1.6 8.6 1.4 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TauD PF02668.11 KND91966.1 - 1.6e-42 145.9 0.0 1.9e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.6 KND91966.1 - 0.082 12.6 0.3 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Transp_cyt_pur PF02133.10 KND91967.1 - 3.7e-25 88.3 30.3 5.3e-25 87.8 21.0 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.20 KND91968.1 - 2.3e-05 23.6 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SGL PF08450.7 KND91970.1 - 2.4e-05 23.8 0.0 0.0022 17.3 0.0 2.8 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region DUF2953 PF11167.3 KND91971.1 - 0.45 10.4 1.8 7.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) ADH_zinc_N PF00107.21 KND91972.1 - 1.6e-13 50.3 0.1 3e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 KND91972.1 - 0.014 15.2 0.4 0.024 14.5 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase PALP PF00291.20 KND91972.1 - 0.028 13.6 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_N PF08240.7 KND91972.1 - 0.034 13.9 0.0 0.14 11.9 0.0 2.0 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain APH PF01636.18 KND91973.1 - 4.3e-10 39.7 0.0 6.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND91973.1 - 0.0009 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ABM PF03992.11 KND91975.1 - 0.097 12.7 0.0 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase GHMP_kinases_C PF08544.8 KND91976.1 - 1.2e-08 35.0 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal TerB PF05099.8 KND91976.1 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB GHMP_kinases_N PF00288.21 KND91976.1 - 0.094 12.7 0.1 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain Ish1 PF10281.4 KND91977.1 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF1470 PF07336.6 KND91977.1 - 0.099 12.9 0.4 0.099 12.9 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) Ribosomal_L38e PF01781.13 KND91978.1 - 2.3e-33 113.7 5.3 2.6e-33 113.6 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family LAGLIDADG_2 PF03161.8 KND91978.1 - 0.083 12.7 0.2 0.093 12.6 0.2 1.1 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family pRN1_helical PF13010.1 KND91978.1 - 0.49 10.0 3.8 0.69 9.5 2.6 1.3 1 1 0 1 1 1 0 Primase helical domain HAD_2 PF13419.1 KND91979.1 - 1.4e-23 84.0 0.0 4.3e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND91979.1 - 0.00035 20.2 0.0 0.00084 19.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Prenyltrans_2 PF13249.1 KND91979.1 - 0.026 14.9 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Prenyltransferase-like LktC PF06261.6 KND91979.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Cupin_1 PF00190.17 KND91980.1 - 1.2e-24 86.3 0.0 8.4e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KND91980.1 - 4e-22 77.5 0.0 1.6e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KND91980.1 - 9.6e-08 31.3 0.0 0.00012 21.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 KND91980.1 - 1.8e-05 24.4 0.0 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.7 KND91980.1 - 0.00024 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.14 KND91980.1 - 0.00052 19.7 0.0 0.0055 16.3 0.0 2.4 3 0 0 3 3 3 1 AraC-like ligand binding domain DUF1971 PF09313.6 KND91980.1 - 0.035 13.8 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) Glyco_hydro_18 PF00704.23 KND91981.1 - 8e-18 64.9 9.7 1.6e-17 64.0 6.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.20 KND91982.1 - 6.6e-11 42.4 0.3 1e-10 41.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND91982.1 - 9e-05 22.2 0.2 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Protoglobin PF11563.3 KND91983.1 - 1.3e-56 190.6 0.1 1.5e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin PPTA PF01239.17 KND91984.1 - 4.3e-40 133.4 3.8 2.5e-07 29.7 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 KND91984.1 - 0.0021 17.7 0.5 0.029 14.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND91984.1 - 0.025 14.5 0.2 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND91984.1 - 0.043 13.7 0.6 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND91984.1 - 0.053 13.3 0.4 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TIP120 PF08623.5 KND91985.1 - 5.5e-57 192.0 12.1 2.5e-38 131.3 0.0 6.4 5 1 2 7 7 7 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KND91985.1 - 2.5e-18 66.1 23.2 0.01 16.1 0.1 9.9 4 3 8 12 12 12 7 HEAT repeats Adaptin_N PF01602.15 KND91985.1 - 1.1e-14 53.6 16.7 0.00018 19.9 3.0 6.7 6 2 1 7 7 7 6 Adaptin N terminal region HEAT PF02985.17 KND91985.1 - 2.5e-11 42.6 24.2 0.32 11.1 0.0 10.9 13 0 0 13 13 12 5 HEAT repeat Cnd1 PF12717.2 KND91985.1 - 1.4e-09 38.0 9.2 0.59 9.9 0.0 6.7 4 3 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 KND91985.1 - 2.7e-05 23.9 11.8 0.043 13.7 0.1 6.3 7 0 0 7 7 7 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KND91985.1 - 8.1e-05 22.9 26.1 4.1 8.0 0.0 11.5 12 3 3 15 15 15 1 HEAT-like repeat VHS PF00790.14 KND91985.1 - 0.0024 17.5 0.1 3.7 7.1 0.0 3.3 3 0 0 3 3 3 2 VHS domain Arm PF00514.18 KND91985.1 - 0.18 11.6 12.9 3.1 7.7 0.1 7.5 9 1 1 10 10 10 0 Armadillo/beta-catenin-like repeat DUF3361 PF11841.3 KND91985.1 - 0.43 10.2 9.3 46 3.7 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) MMS19_N PF14500.1 KND91985.1 - 3.5 6.8 11.7 14 4.8 0.1 5.3 6 2 2 8 8 8 0 Dos2-interacting transcription regulator of RNA-Pol-II IPPT PF01715.12 KND91986.1 - 5.6e-55 186.0 0.0 9.3e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 KND91986.1 - 4.4e-06 26.0 0.1 0.0018 17.5 0.0 2.4 2 0 0 2 2 2 2 Isopentenyl transferase AAA_33 PF13671.1 KND91986.1 - 0.00044 20.1 0.3 0.15 11.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.3 KND91986.1 - 0.001 19.1 0.4 0.0024 17.9 0.0 1.9 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding AAA_19 PF13245.1 KND91986.1 - 0.0047 16.6 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain zf-met PF12874.2 KND91986.1 - 0.005 16.9 0.1 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_17 PF13207.1 KND91986.1 - 0.0087 16.8 0.5 0.056 14.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND91986.1 - 0.028 14.7 0.1 0.62 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KND91986.1 - 0.057 12.5 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 KND91986.1 - 0.069 13.1 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 KND91986.1 - 0.081 12.1 0.1 0.33 10.1 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein AAA_22 PF13401.1 KND91986.1 - 0.097 12.8 0.0 0.61 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.2 KND91986.1 - 0.13 12.4 0.4 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF87 PF01935.12 KND91986.1 - 0.14 11.9 0.7 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 zf-U1 PF06220.7 KND91986.1 - 0.23 11.0 1.2 2.1 7.9 0.1 2.5 2 0 0 2 2 2 0 U1 zinc finger ABC_tran PF00005.22 KND91987.1 - 6.8e-52 175.3 0.0 2.3e-31 108.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND91987.1 - 1e-44 153.0 21.3 2e-25 89.7 3.2 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KND91987.1 - 3.4e-09 36.2 0.5 0.0025 17.0 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND91987.1 - 3.9e-07 30.5 2.8 0.0014 19.0 0.0 2.9 4 0 0 4 4 2 2 AAA domain AAA_21 PF13304.1 KND91987.1 - 2.5e-06 27.6 0.8 0.57 10.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain T2SE PF00437.15 KND91987.1 - 4e-05 22.6 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 KND91987.1 - 6.1e-05 22.5 0.0 0.34 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND91987.1 - 0.00015 21.2 0.4 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KND91987.1 - 0.00064 18.8 2.2 0.56 9.2 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KND91987.1 - 0.0009 19.2 0.3 0.17 11.8 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KND91987.1 - 0.0023 17.4 0.5 0.62 9.4 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain IstB_IS21 PF01695.12 KND91987.1 - 0.0034 16.8 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 KND91987.1 - 0.0053 16.8 0.0 19 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KND91987.1 - 0.0085 15.8 1.1 8.5 6.0 0.1 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KND91987.1 - 0.009 16.8 0.0 3.7 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KND91987.1 - 0.0092 15.1 0.2 3.8 6.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 KND91987.1 - 0.012 15.4 0.0 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 KND91987.1 - 0.015 15.2 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 KND91987.1 - 0.028 14.2 0.3 0.028 14.2 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 Miro PF08477.8 KND91987.1 - 0.029 14.8 0.3 3.9 7.9 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KND91987.1 - 0.038 13.4 0.4 4 6.8 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.24 KND91987.1 - 0.048 13.8 0.5 52 4.0 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KND91987.1 - 0.054 13.8 0.0 19 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KND91987.1 - 0.1 12.1 3.2 4.3 6.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 KND91987.1 - 0.11 11.0 3.1 1.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 KND91987.1 - 0.17 11.3 0.2 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 KND91987.1 - 0.18 11.4 0.9 3.1 7.4 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KND91987.1 - 0.35 10.5 1.9 14 5.3 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Homeobox PF00046.24 KND91988.1 - 1.9e-19 69.0 3.2 3.9e-19 68.0 2.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KND91988.1 - 0.0026 17.4 0.5 0.0026 17.4 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain Adaptin_binding PF10199.4 KND91989.1 - 3e-16 59.9 8.4 5e-16 59.2 5.8 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 ADH_zinc_N_2 PF13602.1 KND91990.1 - 1.8e-15 57.9 0.7 1.4e-14 55.0 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KND91990.1 - 1.4e-08 34.3 0.3 3.1e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UvdE PF03851.9 KND91991.1 - 2.9e-110 367.6 0.0 4.2e-110 367.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE MutS_IV PF05190.13 KND91991.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV Fungal_trans_2 PF11951.3 KND91992.1 - 0.00023 19.9 0.0 0.00024 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KND91993.1 - 0.053 12.3 0.3 0.065 12.0 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 KND91994.1 - 0.0059 16.4 3.2 0.0094 15.8 2.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 KND91995.1 - 2.1e-26 92.8 0.3 2.9e-26 92.3 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KND91995.1 - 0.012 14.9 0.2 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3632 PF12311.3 KND91997.1 - 7e-19 68.3 1.5 1.7e-18 67.1 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) DAO PF01266.19 KND91998.1 - 1.2e-34 119.8 0.0 2.1e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND91998.1 - 2.3e-05 24.3 0.1 7.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND91998.1 - 0.00034 20.5 0.4 0.028 14.2 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KND91998.1 - 0.00062 19.8 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KND91998.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Thi4 PF01946.12 KND91998.1 - 0.0041 16.2 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KND91998.1 - 0.012 14.5 0.1 3 6.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KND91998.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KND91998.1 - 0.057 13.1 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KND91998.1 - 0.059 13.7 0.1 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND91998.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND91998.1 - 0.094 11.3 0.4 1.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.19 KND91999.1 - 1.1e-29 103.3 1.9 1.3e-29 103.1 1.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Apc13p PF05839.6 KND92000.1 - 6e-35 119.1 0.1 7.7e-35 118.7 0.1 1.1 1 0 0 1 1 1 1 Apc13p protein Zn_clus PF00172.13 KND92001.1 - 1.2e-05 25.0 11.1 2.1e-05 24.3 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.15 KND92002.1 - 4.5e-07 28.7 0.0 6.5e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Defensin_1 PF00323.14 KND92002.1 - 0.099 13.0 1.2 0.22 11.9 0.9 1.5 1 0 0 1 1 1 0 Mammalian defensin SecY PF00344.15 KND92003.1 - 9.2e-95 317.4 9.9 1.2e-94 317.0 6.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KND92003.1 - 2e-17 62.3 0.1 1.1e-16 60.0 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p E1-E2_ATPase PF00122.15 KND92004.1 - 2.3e-16 59.5 0.0 5.6e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND92004.1 - 9.4e-15 55.5 0.0 1e-13 52.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND92004.1 - 9.8e-14 51.9 0.6 1.7e-12 47.8 0.4 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND92004.1 - 7.5e-11 41.8 0.0 2.1e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND92004.1 - 0.00062 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SnoaL PF07366.7 KND92005.1 - 4.9e-07 29.3 0.0 7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KND92005.1 - 0.0084 16.5 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2530 PF10745.4 KND92006.1 - 0.17 11.8 0.2 0.17 11.8 0.1 4.1 4 2 1 5 5 5 0 Protein of unknown function (DUF2530) TMEM192 PF14802.1 KND92006.1 - 0.82 8.4 3.8 2.9 6.6 0.1 2.7 2 1 1 3 3 3 0 TMEM192 family Cupin_3 PF05899.7 KND92007.1 - 0.00068 18.9 0.1 0.0025 17.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) CENP-C_C PF11699.3 KND92007.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_2 PF07883.6 KND92007.1 - 0.039 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF676 PF05057.9 KND92008.1 - 1.4e-05 24.4 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND92008.1 - 0.0035 16.9 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KND92008.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KND92008.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase IncA PF04156.9 KND92008.1 - 2 7.9 4.7 4.4 6.8 3.2 1.5 1 0 0 1 1 1 0 IncA protein BTB PF00651.26 KND92009.1 - 0.00016 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-ribbon_3 PF13248.1 KND92009.1 - 0.0026 16.8 2.1 0.0072 15.4 1.5 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zf-C2HC5 PF06221.8 KND92009.1 - 0.034 13.9 1.8 0.034 13.9 1.3 1.9 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Spt4 PF06093.8 KND92009.1 - 0.076 12.9 2.0 0.16 11.8 1.4 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DUF2076 PF09849.4 KND92012.1 - 0.015 15.4 0.4 0.018 15.0 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.14 KND92013.1 - 1.8e-24 85.3 0.1 3.3e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein FAD_binding_3 PF01494.14 KND92014.1 - 1.1e-25 90.4 0.0 3.4e-25 88.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND92014.1 - 1.6e-10 40.4 0.5 0.00031 19.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND92014.1 - 3.7e-07 30.0 0.3 9e-06 25.6 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND92014.1 - 8.9e-06 26.0 0.1 0.0056 17.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KND92014.1 - 3.7e-05 22.6 0.0 0.0076 15.1 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.19 KND92014.1 - 6.5e-05 22.1 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KND92014.1 - 9.8e-05 21.4 0.4 0.017 14.0 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 KND92014.1 - 0.00018 20.1 0.0 0.07 11.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KND92014.1 - 0.00033 20.7 0.0 0.00074 19.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND92014.1 - 0.00071 18.5 1.4 0.00088 18.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KND92014.1 - 0.00082 19.2 0.1 0.002 18.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND92014.1 - 0.0031 16.2 0.2 1.6 7.2 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KND92014.1 - 0.0036 17.0 1.1 0.063 13.0 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KND92014.1 - 0.0087 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KND92014.1 - 0.022 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KND92014.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 KND92014.1 - 0.13 11.1 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Adap_comp_sub PF00928.16 KND92015.1 - 1.2e-90 303.1 0.0 1.6e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KND92015.1 - 8.6e-08 31.9 0.2 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KND92015.1 - 0.14 11.3 0.0 0.51 9.4 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain SET PF00856.23 KND92016.1 - 2.1e-13 50.8 0.0 8.1e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KND92016.1 - 6.9e-05 22.7 0.3 0.00014 21.8 0.2 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding zf-RING_2 PF13639.1 KND92017.1 - 1.9e-07 30.7 0.1 6.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 KND92017.1 - 0.0004 19.9 0.1 0.0071 15.9 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND92017.1 - 0.00043 19.9 0.2 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KND92017.1 - 0.00045 20.2 0.1 0.0071 16.4 0.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND92017.1 - 0.00048 20.0 0.4 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KND92017.1 - 0.0019 18.0 1.4 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.1 KND92017.1 - 0.0029 17.3 0.2 0.43 10.3 0.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KND92017.1 - 0.0085 15.9 0.1 0.35 10.7 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rubredoxin PF00301.15 KND92017.1 - 0.016 15.0 0.1 0.053 13.3 0.1 1.9 1 0 0 1 1 1 0 Rubredoxin zf-C3HC4_3 PF13920.1 KND92017.1 - 0.039 13.6 0.2 5.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND92017.1 - 0.049 13.5 0.5 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING E1-E2_ATPase PF00122.15 KND92018.1 - 3.2e-63 212.8 3.6 5.7e-63 212.0 2.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND92018.1 - 1.8e-34 118.8 7.7 1.8e-34 118.8 5.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND92018.1 - 2.6e-31 109.7 0.1 3.3e-26 93.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND92018.1 - 7e-16 57.9 0.0 1.6e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KND92018.1 - 7.9e-14 50.8 0.6 2.2e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KND92018.1 - 1.2e-13 51.6 0.0 3.4e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND92018.1 - 5.6e-05 22.8 0.1 0.00042 19.9 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3435 PF11917.3 KND92019.1 - 2.3e-45 155.1 0.0 1.4e-40 139.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) Phage_int_SAM_4 PF13495.1 KND92019.1 - 0.0019 18.4 0.3 0.0083 16.4 0.2 2.1 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain CDC45 PF02724.9 KND92019.1 - 2.3 6.1 8.2 3.6 5.5 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CwfJ_C_1 PF04677.10 KND92021.1 - 2.4e-29 101.4 0.0 3.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KND92021.1 - 5.1e-21 74.9 0.0 1.7e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Trypsin PF00089.21 KND92022.1 - 8.2e-09 35.3 0.2 1.5e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KND92022.1 - 0.00064 19.6 1.0 0.0016 18.4 0.7 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Mpv17_PMP22 PF04117.7 KND92023.1 - 9.1e-23 79.6 0.3 9.1e-23 79.6 0.2 2.4 2 1 1 3 3 3 1 Mpv17 / PMP22 family PGK PF00162.14 KND92024.1 - 2.5e-153 510.1 0.5 2.9e-153 510.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peripla_BP_4 PF13407.1 KND92024.1 - 0.016 14.5 0.5 0.038 13.3 0.4 1.6 1 0 0 1 1 1 0 Periplasmic binding protein domain ADH_zinc_N PF00107.21 KND92024.1 - 0.028 13.9 0.1 0.33 10.4 0.0 2.6 3 0 0 3 3 3 0 Zinc-binding dehydrogenase PrpR_N PF06506.6 KND92024.1 - 0.11 11.9 0.5 11 5.4 0.1 2.8 3 0 0 3 3 3 0 Propionate catabolism activator FIVAR PF07554.8 KND92024.1 - 0.18 12.0 3.2 6 7.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain FA_hydroxylase PF04116.8 KND92026.1 - 0.00018 21.8 10.7 0.00031 21.1 7.4 1.5 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily Abhydrolase_6 PF12697.2 KND92027.1 - 1.2e-20 74.4 0.2 7.8e-20 71.7 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92027.1 - 2.2e-09 37.2 0.0 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND92027.1 - 5e-07 29.4 0.0 1.3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KND92027.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DSS1_SEM1 PF05160.8 KND92028.1 - 5.8e-24 83.6 12.8 7.5e-24 83.2 8.8 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.4 KND92029.1 - 1.1e-119 400.0 0.0 1.7e-119 399.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 KND92029.1 - 0.0016 18.6 12.6 0.021 15.1 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KND92029.1 - 0.003 17.4 2.7 0.031 14.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND92029.1 - 0.06 13.2 1.4 2.8 7.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sulfatase PF00884.18 KND92030.1 - 2.8e-14 53.0 0.0 3.3e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Peptidase_M7 PF02031.11 KND92030.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family MFS_1 PF07690.11 KND92032.1 - 1.6e-39 135.6 56.5 1.6e-39 135.6 39.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KND92033.1 - 0.0065 16.3 4.0 0.013 15.3 2.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 KND92034.1 - 3.1e-21 75.8 1.0 1.3e-20 73.8 0.7 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KND92034.1 - 8.9e-09 35.1 1.5 9.4e-09 35.0 0.2 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KND92034.1 - 0.00094 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KND92034.1 - 0.012 14.0 0.0 0.029 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.19 KND92036.1 - 1.9e-07 30.0 0.4 2.2e-07 29.8 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TetR_C_2 PF08361.6 KND92036.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Phosphoesterase PF04185.9 KND92037.1 - 2.6e-76 257.2 7.9 3.4e-76 256.8 5.5 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 KND92040.1 - 3.6e-35 120.2 2.3 3.9e-34 116.9 0.1 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND92040.1 - 5.7e-33 113.3 5.1 1.6e-29 102.1 0.5 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KND92040.1 - 1.3e-13 51.1 0.0 3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase MULE PF10551.4 KND92041.1 - 6.1e-15 55.1 0.0 1.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 KND92041.1 - 0.00016 20.3 0.1 0.00041 19.0 0.0 1.6 2 0 0 2 2 2 1 Transposase, Mutator family Tau95 PF09734.4 KND92042.1 - 2.7e-61 207.5 0.0 3.7e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF750 PF04721.12 KND92042.1 - 0.093 12.7 0.5 0.74 9.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF750) CRAL_TRIO PF00650.15 KND92043.1 - 3.3e-37 127.4 0.0 8e-37 126.1 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain Exo_endo_phos PF03372.18 KND92043.1 - 7.2e-27 94.9 0.4 1.2e-26 94.1 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CRAL_TRIO_N PF03765.10 KND92043.1 - 5.5e-09 36.0 1.0 1.5e-08 34.6 0.7 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KND92043.1 - 0.052 13.4 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CTD_bind PF04818.8 KND92044.1 - 0.00083 19.5 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Ribosom_S12_S23 PF00164.20 KND92045.1 - 3.3e-41 139.5 1.1 4.2e-41 139.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 KND92046.1 - 4e-143 476.3 1.7 5e-143 476.0 1.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 KND92046.1 - 0.0068 16.1 0.6 0.019 14.7 0.4 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor PAT1 PF09770.4 KND92047.1 - 6.1e-235 782.2 12.3 6.9e-235 782.0 8.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sin_N PF04801.8 KND92048.1 - 1.7e-16 60.1 3.0 3.3e-09 36.1 0.3 2.2 1 1 0 2 2 2 2 Sin-like protein conserved region EMP70 PF02990.11 KND92049.1 - 1.6e-193 643.9 2.4 1.9e-193 643.7 1.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KND92049.1 - 0.047 13.8 0.0 0.047 13.8 0.0 4.2 3 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding PIRT PF15099.1 KND92049.1 - 0.14 11.3 1.0 0.34 10.1 0.7 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Med4 PF10018.4 KND92050.1 - 1.9e-41 141.5 17.1 4e-41 140.4 11.8 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 UDPG_MGDP_dh_C PF03720.10 KND92050.1 - 0.097 12.8 0.3 0.23 11.6 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Atg14 PF10186.4 KND92050.1 - 0.81 8.5 9.6 0.39 9.6 2.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KND92050.1 - 6.5 5.0 12.2 0.6 8.5 0.5 2.1 2 0 0 2 2 2 0 AAA domain DUF2422 PF10337.4 KND92050.1 - 10 4.8 6.5 1.3 7.7 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Methyltransf_31 PF13847.1 KND92051.1 - 1.1e-26 93.2 0.0 1.5e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND92051.1 - 1.3e-24 86.5 0.1 2.4e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND92051.1 - 6e-18 64.8 0.0 1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KND92051.1 - 2.7e-16 59.8 0.1 4.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND92051.1 - 2.9e-16 59.6 0.0 4.6e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND92051.1 - 2e-15 57.3 0.0 3.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND92051.1 - 7.9e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KND92051.1 - 3.1e-11 43.0 0.0 4.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KND92051.1 - 8.9e-10 38.6 0.1 2.1e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND92051.1 - 9.3e-09 35.1 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KND92051.1 - 3.5e-08 32.9 0.0 5.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KND92051.1 - 4.4e-08 32.4 0.0 9.1e-08 31.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 KND92051.1 - 7.6e-06 24.8 0.0 2.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KND92051.1 - 3.6e-05 22.9 0.0 4.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KND92051.1 - 5.4e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) GidB PF02527.10 KND92051.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G RrnaAD PF00398.15 KND92051.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 KND92051.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase UPF0020 PF01170.13 KND92051.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.9 KND92051.1 - 0.0068 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 KND92051.1 - 0.014 15.0 0.1 0.064 12.8 0.1 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.13 KND92051.1 - 0.11 11.7 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NAD_binding_2 PF03446.10 KND92052.1 - 7.5e-39 133.1 1.1 1.1e-38 132.6 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KND92052.1 - 7.7e-30 103.4 0.1 7.7e-30 103.4 0.1 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KND92052.1 - 5.6e-07 29.8 0.0 1.3e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KND92052.1 - 3.1e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.10 KND92052.1 - 3.6e-05 22.6 0.0 6.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 KND92052.1 - 0.00023 21.6 0.1 0.00093 19.7 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ldh_1_N PF00056.18 KND92052.1 - 0.00026 20.8 0.2 0.00054 19.7 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MTS PF05175.9 KND92052.1 - 0.028 13.8 0.1 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain 3HCDH_N PF02737.13 KND92052.1 - 0.033 13.8 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 KND92052.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KND92052.1 - 0.05 13.7 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Actin PF00022.14 KND92054.1 - 7e-156 518.5 0.0 8.1e-156 518.3 0.0 1.0 1 0 0 1 1 1 1 Actin Nuf2 PF03800.9 KND92055.1 - 3e-45 153.7 0.1 3e-45 153.7 0.1 2.3 2 0 0 2 2 2 1 Nuf2 family Synaptobrevin PF00957.16 KND92055.1 - 0.72 9.4 6.8 3 7.5 0.1 3.3 2 1 0 2 2 2 0 Synaptobrevin Reo_sigmaC PF04582.7 KND92055.1 - 0.77 8.8 4.2 0.62 9.1 1.2 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Caldesmon PF02029.10 KND92055.1 - 8.8 4.6 40.3 0.6 8.4 15.2 2.2 2 0 0 2 2 2 0 Caldesmon RTA1 PF04479.8 KND92057.1 - 1.8e-11 43.9 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RTA1 like protein MnhB PF04039.8 KND92057.1 - 0.041 13.9 4.4 0.066 13.2 3.1 1.3 1 1 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF2754 PF10953.3 KND92057.1 - 0.2 11.7 3.1 0.43 10.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) DUF4131 PF13567.1 KND92057.1 - 6.8 6.0 6.8 1.4 8.3 2.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Adaptin_N PF01602.15 KND92058.1 - 6.4e-100 334.9 0.0 7.3e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KND92058.1 - 8.4e-13 48.4 1.6 4e-05 23.8 0.0 4.5 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KND92058.1 - 2.3e-09 36.5 0.8 0.026 14.5 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KND92058.1 - 1.5e-05 25.3 7.2 0.005 17.3 0.0 5.2 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KND92058.1 - 0.00013 21.7 0.3 0.14 12.1 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KND92058.1 - 0.0015 18.4 0.0 0.17 11.6 0.0 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KND92058.1 - 0.0039 16.5 0.3 6.7 6.0 0.0 3.2 2 1 1 3 3 3 2 CLASP N terminal Thioredoxin PF00085.15 KND92059.1 - 2.4e-27 94.6 0.3 3.2e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KND92059.1 - 2.8e-07 30.7 0.7 3.2e-06 27.2 0.5 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KND92059.1 - 5.3e-06 26.3 0.2 8.9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KND92059.1 - 7.9e-05 22.2 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KND92059.1 - 0.00015 21.3 0.5 0.0004 19.9 0.3 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 KND92059.1 - 0.00017 21.6 0.1 0.0027 17.7 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.19 KND92059.1 - 0.011 15.7 0.2 0.038 13.9 0.1 2.0 1 1 1 2 2 2 0 Glutaredoxin AhpC-TSA PF00578.16 KND92059.1 - 0.037 13.7 0.2 0.34 10.6 0.1 1.9 1 1 1 2 2 2 0 AhpC/TSA family Sulfatase PF00884.18 KND92061.1 - 2.3e-55 187.9 0.1 3.6e-55 187.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase F-box-like PF12937.2 KND92062.1 - 0.00015 21.3 0.1 0.00015 21.3 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KND92062.1 - 0.00016 21.2 0.3 0.00064 19.3 0.2 2.1 1 0 0 1 1 1 1 F-box domain GAT PF03127.9 KND92063.1 - 5.6e-16 58.3 0.3 1.3e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 KND92063.1 - 2e-05 24.2 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain Fungal_trans PF04082.13 KND92065.1 - 7e-16 57.8 1.0 1.2e-15 57.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND92065.1 - 1.1e-08 34.7 15.0 2.2e-08 33.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.19 KND92065.1 - 0.15 11.3 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HypA PF01155.14 KND92065.1 - 3.6 7.3 6.2 6.1 6.5 4.3 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Mito_carr PF00153.22 KND92066.1 - 7.9e-61 201.7 0.3 9.1e-24 82.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 KND92066.1 - 0.0095 15.8 10.6 0.02 14.8 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3995 PF13160.1 KND92067.1 - 0.16 12.0 2.8 0.58 10.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF754 PF05449.6 KND92067.1 - 0.58 10.2 3.2 1.3 9.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF754) Acetyltransf_1 PF00583.19 KND92069.1 - 1.7e-15 56.7 0.1 2.6e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND92069.1 - 4.7e-12 45.9 0.0 6.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND92069.1 - 2.9e-10 40.2 0.1 3.8e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND92069.1 - 7.8e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND92069.1 - 1.7e-07 30.8 0.0 3.2e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KND92069.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND92069.1 - 0.00023 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KND92069.1 - 0.031 14.1 0.0 0.071 12.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UBA_4 PF14555.1 KND92070.1 - 3.9e-10 39.1 0.0 8.3e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KND92070.1 - 9.9e-08 31.9 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain SUFU_C PF12470.3 KND92070.1 - 0.0062 16.1 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain Pkinase PF00069.20 KND92071.1 - 0.00018 20.7 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND92071.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.19 KND92071.1 - 0.031 13.9 0.5 0.064 12.9 0.4 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CorA PF01544.13 KND92072.1 - 6e-14 51.7 0.1 1.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DivIVA PF05103.8 KND92072.1 - 0.063 13.3 0.4 7.2 6.6 0.1 2.4 2 0 0 2 2 2 0 DivIVA protein RasGAP PF00616.14 KND92073.1 - 8.8e-55 185.4 0.1 6.4e-54 182.6 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KND92073.1 - 5.4e-30 103.9 5.8 5.4e-30 103.9 4.0 2.2 2 0 0 2 2 2 1 RasGAP C-terminus CENP-F_leu_zip PF10473.4 KND92073.1 - 2 8.2 12.5 0.45 10.3 2.5 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HET PF06985.6 KND92074.1 - 9.1e-22 77.7 0.5 1.8e-21 76.7 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KND92075.1 - 2.1e-32 112.2 19.4 2.1e-32 112.2 13.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Lgl_C PF08596.5 KND92076.1 - 6.5e-123 410.0 0.0 1.1e-122 409.3 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KND92076.1 - 4.3e-05 23.2 5.7 0.0034 17.1 0.2 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 KND92076.1 - 0.028 12.5 0.0 8.4 4.3 0.0 3.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Piwi PF02171.12 KND92077.1 - 2.8e-78 262.9 0.0 4.3e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KND92077.1 - 6e-12 45.0 0.1 1.4e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KND92077.1 - 3.6e-09 35.8 0.0 1.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Suf PF05843.9 KND92078.1 - 4.8e-76 256.1 2.7 7.1e-76 255.6 0.0 2.8 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KND92078.1 - 0.0016 18.9 1.9 0.027 15.1 0.1 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND92078.1 - 0.01 16.5 0.2 0.07 13.8 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat HAT PF02184.11 KND92078.1 - 0.02 14.5 0.0 0.28 10.9 0.1 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat HrpJ PF07201.6 KND92078.1 - 0.034 14.1 3.3 1.4 8.8 0.0 3.6 4 0 0 4 4 4 0 HrpJ-like domain PP2C_C PF07830.8 KND92078.1 - 0.13 12.4 0.1 0.98 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain ASF1_hist_chap PF04729.8 KND92079.1 - 3.4e-64 215.1 0.0 4.5e-64 214.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone APH PF01636.18 KND92081.1 - 8.6e-06 25.6 0.0 9.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KND92081.1 - 0.0023 17.1 0.0 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92081.1 - 0.031 13.3 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.9 KND92081.1 - 0.078 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase FAD_binding_2 PF00890.19 KND92082.1 - 2e-21 76.3 0.2 2.4e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND92082.1 - 7.1e-06 25.1 0.4 8.6e-06 24.8 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KND92082.1 - 1.2e-05 24.6 1.0 1.4e-05 24.3 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND92082.1 - 0.0021 17.9 0.9 0.0029 17.5 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND92082.1 - 0.0024 17.8 1.2 0.004 17.1 0.9 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KND92082.1 - 0.0079 14.7 0.6 0.01 14.3 0.4 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KND92082.1 - 0.03 13.4 0.2 0.042 12.9 0.2 1.1 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KND92082.1 - 0.036 13.1 1.1 0.048 12.7 0.8 1.2 1 0 0 1 1 1 0 FAD binding domain RrnaAD PF00398.15 KND92082.1 - 0.065 12.2 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GIDA PF01134.17 KND92082.1 - 0.48 9.2 2.3 0.6 8.9 1.6 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KND92083.1 - 6.1e-05 22.0 0.0 7.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Git3 PF11710.3 KND92084.1 - 6.4e-20 71.5 0.3 6.4e-20 71.5 0.2 2.6 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KND92084.1 - 5.8e-11 42.0 7.2 6.6e-11 41.8 4.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KND92084.1 - 8.4e-06 24.8 2.1 1.5e-05 24.0 1.4 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 KND92084.1 - 0.00027 20.6 0.3 0.0013 18.4 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term PBP1_TM PF14812.1 KND92084.1 - 0.051 13.8 2.8 0.14 12.4 2.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KND92084.1 - 1.2 8.3 3.8 1.8 7.7 2.6 1.2 1 0 0 1 1 1 0 NOA36 protein SelP_N PF04592.9 KND92084.1 - 1.5 8.1 6.7 2.3 7.5 4.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-DHHC PF01529.15 KND92085.1 - 5.6e-29 100.7 1.9 5.6e-29 100.7 1.3 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF373 PF04123.8 KND92085.1 - 0.1 11.6 0.1 0.1 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4131 PF13567.1 KND92085.1 - 0.59 9.5 7.1 0.96 8.8 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MARVEL PF01284.18 KND92085.1 - 1.2 8.9 15.3 1.1 9.1 6.0 2.5 2 1 1 3 3 3 0 Membrane-associating domain DUF4117 PF13491.1 KND92085.1 - 1.5 8.2 8.3 4.2 6.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) DUF1129 PF06570.6 KND92085.1 - 1.6 7.9 5.2 1.9 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) YjgP_YjgQ PF03739.9 KND92085.1 - 2.5 6.7 11.6 0.56 8.8 2.8 2.1 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family tRNA-synt_1 PF00133.17 KND92086.1 - 5e-193 642.3 0.0 7.6e-193 641.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KND92086.1 - 1.4e-24 86.5 0.0 2.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KND92086.1 - 4.3e-18 65.1 2.9 4.8e-07 28.7 0.4 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KND92086.1 - 1.3e-05 24.4 0.0 0.0002 20.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain FAD_binding_2 PF00890.19 KND92088.1 - 4.5e-06 25.7 0.0 5.2e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.2 KND92089.1 - 6.8e-06 25.7 0.5 2.1e-05 24.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND92089.1 - 0.026 14.1 1.6 0.08 12.6 1.1 1.9 1 0 0 1 1 1 0 F-box domain RAP1 PF07218.6 KND92090.1 - 0.55 8.2 11.6 1.1 7.3 8.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAD_binding_3 PF01494.14 KND92092.1 - 1.5e-13 50.5 0.6 5.6e-09 35.5 0.1 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KND92092.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND92092.1 - 0.042 12.7 0.1 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4520 PF15016.1 KND92092.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) FMN_red PF03358.10 KND92093.1 - 5.1e-17 61.7 0.0 1.5e-15 57.0 0.0 2.1 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KND92093.1 - 0.019 14.4 0.4 0.13 11.7 0.3 2.2 1 1 0 1 1 1 0 Flavodoxin-like fold SYS1 PF09801.4 KND92094.1 - 6.9e-47 159.0 5.9 8e-47 158.8 4.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TrbE PF11100.3 KND92094.1 - 0.29 11.0 3.2 0.47 10.3 1.3 2.0 1 1 1 2 2 2 0 Conjugal transfer protein TrbE Virul_fac_BrkB PF03631.10 KND92094.1 - 3.6 6.8 15.1 13 5.0 10.5 1.7 1 1 0 1 1 1 0 Virulence factor BrkB CPSF100_C PF13299.1 KND92095.1 - 4e-40 137.6 0.1 1.3e-39 135.9 0.0 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KND92095.1 - 5.1e-27 94.3 0.0 1.3e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KND92095.1 - 8.5e-06 25.4 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Sec2p PF06428.6 KND92096.1 - 1.4e-24 85.8 15.6 1.4e-24 85.8 10.8 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Filament PF00038.16 KND92096.1 - 3.2 7.1 27.6 7 6.0 14.2 2.1 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.2 KND92096.1 - 3.3 7.5 28.0 1.8 8.4 17.3 2.0 1 1 0 1 1 1 0 Tropomyosin like HlyD PF00529.15 KND92096.1 - 5.8 6.1 24.4 1.7 7.8 14.7 1.7 1 1 0 1 1 1 0 HlyD family secretion protein DUF3584 PF12128.3 KND92096.1 - 8.1 3.6 28.3 18 2.4 19.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) COX6B PF02297.12 KND92097.1 - 8.9e-20 70.4 1.2 1.2e-19 70.0 0.8 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb PRP21_like_P PF12230.3 KND92098.1 - 1.8e-53 181.3 18.3 3.8e-53 180.3 11.5 2.1 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KND92098.1 - 2.6e-30 103.8 0.8 2.5e-14 52.6 0.0 2.4 2 0 0 2 2 2 2 Surp module PMT PF02366.13 KND92099.1 - 7.4e-74 248.1 16.7 1.9e-73 246.8 11.6 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KND92099.1 - 5e-53 179.4 0.0 9.2e-53 178.6 0.0 1.5 1 0 0 1 1 1 1 MIR domain MFS_1 PF07690.11 KND92100.1 - 1.7e-13 50.0 49.5 1.7e-13 50.0 34.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PX PF00787.19 KND92101.1 - 2.2e-23 82.1 0.0 3.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 PX domain Kri1_C PF12936.2 KND92103.1 - 4e-27 93.9 0.1 4e-27 93.9 0.0 4.0 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 KND92103.1 - 1.1e-22 80.1 29.2 1.1e-22 80.1 20.3 5.2 6 2 1 7 7 7 1 KRI1-like family Fungal_trans PF04082.13 KND92104.1 - 8.5e-27 93.6 0.0 1.7e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND92104.1 - 1.4e-09 37.6 10.9 2.7e-09 36.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C50 PF03568.12 KND92105.1 - 7.5e-115 383.6 0.0 1.7e-114 382.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KND92105.1 - 2.1e-17 62.7 10.2 4.3e-05 23.3 0.0 7.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KND92105.1 - 2e-06 28.0 4.1 0.0097 16.2 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND92105.1 - 2.1e-06 27.8 1.4 45 5.0 0.0 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND92105.1 - 1.3e-05 24.7 8.1 2 8.5 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND92105.1 - 4.8e-05 22.9 4.6 1.1 8.9 0.0 5.7 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 KND92105.1 - 0.00068 20.2 2.0 7.6 7.3 0.0 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND92105.1 - 0.004 16.8 5.8 1.9 8.4 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.4 KND92105.1 - 0.082 12.2 9.0 0.27 10.5 0.2 5.3 5 2 2 7 7 7 0 26S proteasome subunit RPN7 DUF87 PF01935.12 KND92105.1 - 0.16 11.7 0.6 0.65 9.7 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 TPR_10 PF13374.1 KND92105.1 - 0.47 10.4 5.3 12 5.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KND92105.1 - 0.83 10.2 7.8 1.1e+02 3.7 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND92105.1 - 2.5 7.8 9.2 15 5.3 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SIR2 PF02146.12 KND92106.1 - 7.3e-30 104.0 0.0 1.1e-29 103.4 0.0 1.3 1 1 0 1 1 1 1 Sir2 family TniQ PF06527.6 KND92106.1 - 0.042 14.0 0.3 0.087 13.0 0.2 1.5 1 0 0 1 1 1 0 TniQ CBFD_NFYB_HMF PF00808.18 KND92107.1 - 2.9e-12 46.4 0.6 4.3e-12 45.9 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND92107.1 - 0.0008 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PI3_PI4_kinase PF00454.22 KND92108.1 - 6.2e-31 107.6 0.0 1.1e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KND92108.1 - 1.1e-19 69.8 0.0 2.6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Ras PF00071.17 KND92110.1 - 1e-57 194.0 0.0 1.2e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND92110.1 - 3.4e-20 72.7 0.0 5.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND92110.1 - 3.2e-14 52.5 0.0 5.3e-14 51.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND92110.1 - 1.1e-06 28.1 0.0 2.7e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KND92110.1 - 4.7e-06 25.9 0.0 5.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND92110.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KND92110.1 - 0.0078 16.2 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND92110.1 - 0.052 13.6 0.0 0.22 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF788 PF05620.6 KND92111.1 - 4.4e-42 143.8 0.0 4.8e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF3099 PF11298.3 KND92111.1 - 0.25 11.1 1.7 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DUF962 PF06127.6 KND92111.1 - 3.1 7.7 5.1 49 3.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF2424 PF10340.4 KND92112.1 - 3.2e-22 78.6 0.0 1.9e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KND92112.1 - 1.6e-18 67.0 0.0 2.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KND92112.1 - 0.066 11.9 0.9 6.5 5.3 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family MFS_1 PF07690.11 KND92113.1 - 1.9e-31 109.0 60.6 1.5e-17 63.3 21.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KND92113.1 - 2.3e-12 46.0 34.7 1.9e-11 43.0 13.2 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KND92113.1 - 0.0015 17.1 3.6 0.0015 17.1 2.5 3.0 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 KND92113.1 - 0.0026 17.5 5.7 0.023 14.4 0.3 2.8 2 0 0 2 2 2 2 MFS_1 like family FA_desaturase PF00487.19 KND92114.1 - 1.5e-26 93.3 21.7 3e-26 92.4 15.0 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KND92114.1 - 1.1e-06 28.6 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Acid_PPase PF12689.2 KND92115.1 - 8.2e-62 207.7 0.0 9.9e-62 207.5 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KND92115.1 - 0.098 12.8 0.4 1 9.5 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.15 KND92116.1 - 2.6e-24 85.5 0.0 4.9e-24 84.6 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND92116.1 - 1.4e-10 41.1 0.1 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DDE_Tnp_1_2 PF13586.1 KND92116.1 - 0.026 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HET PF06985.6 KND92117.1 - 4.7e-18 65.6 0.0 9.2e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3405 PF11885.3 KND92118.1 - 2.2e-132 441.8 2.6 2.7e-132 441.5 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Cyclin_N PF00134.18 KND92119.1 - 1.5e-10 40.7 0.0 3.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn_clus PF00172.13 KND92120.1 - 1.7e-09 37.4 11.2 4.2e-09 36.1 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND92120.1 - 0.013 14.3 0.9 0.022 13.6 0.6 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ribosomal_S17e PF00833.13 KND92121.1 - 3.7e-58 194.6 0.3 4.4e-58 194.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KND92121.1 - 0.044 14.4 0.0 0.06 14.0 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 KND92122.1 - 4.9e-66 223.0 0.0 6e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit SH3_9 PF14604.1 KND92123.1 - 1.9e-11 43.3 0.3 5.1e-11 41.9 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND92123.1 - 8.6e-10 37.8 0.3 8.6e-10 37.8 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KND92123.1 - 1.8e-09 36.9 0.0 4.8e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Spc97_Spc98 PF04130.8 KND92124.1 - 3.9e-67 226.7 0.0 1.4e-66 225.0 0.0 1.8 1 1 1 2 2 2 1 Spc97 / Spc98 family DUF4023 PF13215.1 KND92124.1 - 0.0098 15.6 0.6 0.023 14.4 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4023) Senescence PF06911.7 KND92125.1 - 1.2e-46 158.6 4.0 1.8e-46 158.0 2.8 1.3 1 0 0 1 1 1 1 Senescence-associated protein DEC-1_N PF04625.8 KND92125.1 - 0.58 8.7 4.0 0.92 8.1 2.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PIF1 PF05970.9 KND92126.1 - 6.5e-60 202.9 0.1 5e-45 154.0 0.0 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KND92126.1 - 6.5e-16 58.4 0.0 1.5e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND92126.1 - 1.4e-07 31.6 0.0 5.3e-07 29.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KND92126.1 - 5.7e-07 29.1 0.1 1.4e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KND92126.1 - 3.7e-05 23.8 0.1 0.0004 20.4 0.0 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.24 KND92126.1 - 6e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KND92126.1 - 0.0002 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_Helicase PF02689.9 KND92126.1 - 0.00022 19.1 0.1 0.0009 17.1 0.0 1.8 2 0 0 2 2 2 1 Helicase PhoH PF02562.11 KND92126.1 - 0.00069 18.9 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 KND92126.1 - 0.00088 19.3 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KND92126.1 - 0.0016 17.9 0.1 0.36 10.2 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KND92126.1 - 0.0026 17.3 2.0 0.0086 15.6 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KND92126.1 - 0.0035 17.2 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KND92126.1 - 0.0038 17.3 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 KND92126.1 - 0.0045 17.2 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 KND92126.1 - 0.0086 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 KND92126.1 - 0.0089 15.0 0.0 0.034 13.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 KND92126.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 KND92126.1 - 0.014 15.2 1.3 3.9 7.2 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF87 Sigma54_activ_2 PF14532.1 KND92126.1 - 0.019 14.9 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KND92126.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_7 PF12775.2 KND92126.1 - 0.028 13.5 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DUF258 PF03193.11 KND92126.1 - 0.034 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 KND92126.1 - 0.044 13.2 0.5 0.079 12.4 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KND92126.1 - 0.046 12.8 0.1 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KND92126.1 - 0.058 12.1 0.1 0.72 8.5 0.0 2.2 2 0 0 2 2 2 0 ArgK protein IstB_IS21 PF01695.12 KND92126.1 - 0.061 12.7 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 KND92126.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 KND92126.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 KND92126.1 - 0.094 12.4 0.1 0.69 9.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KND92126.1 - 0.1 12.3 0.1 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 KND92126.1 - 0.17 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PalH PF08733.5 KND92128.1 - 3.3e-98 328.7 0.0 4.3e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 Tox-WTIP PF15654.1 KND92128.1 - 0.44 10.1 5.7 0.7 9.5 0.4 2.8 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif YjeF_N PF03853.10 KND92129.1 - 1.9e-36 125.1 0.1 3.8e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KND92129.1 - 6.1e-10 39.5 1.4 6.1e-10 39.5 1.0 2.5 1 1 1 2 2 2 1 FDF domain G-patch_2 PF12656.2 KND92130.1 - 1.1e-20 73.2 1.0 1.1e-20 73.2 0.7 3.5 3 2 1 4 4 4 1 DExH-box splicing factor binding site G-patch PF01585.18 KND92130.1 - 0.046 13.5 1.7 0.26 11.0 1.2 2.4 1 1 0 1 1 1 0 G-patch domain Glyco_transf_28 PF03033.15 KND92131.1 - 2.8e-16 59.5 0.0 6.9e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KND92131.1 - 1e-05 24.2 0.0 3.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KND92131.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Na_H_Exchanger PF00999.16 KND92132.1 - 3e-69 233.3 42.1 3.7e-69 233.0 29.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSA PF07529.8 KND92133.1 - 1.3e-19 69.6 1.2 1.3e-19 69.6 0.8 3.8 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 KND92133.1 - 8.5e-15 54.6 0.4 2.7e-14 52.9 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KND92133.1 - 0.0045 17.0 0.2 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_3 PF13920.1 KND92134.1 - 4.1e-10 39.1 8.9 6e-10 38.6 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND92134.1 - 1e-08 34.8 11.7 1.6e-08 34.2 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND92134.1 - 1.8e-08 34.2 10.1 2.8e-08 33.6 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND92134.1 - 4.1e-06 26.4 10.0 6.5e-06 25.7 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND92134.1 - 7.6e-06 25.4 10.1 1.2e-05 24.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND92134.1 - 0.00014 21.6 5.3 0.00024 20.8 3.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RNHCP PF12647.2 KND92134.1 - 0.002 17.9 2.5 0.0034 17.1 1.7 1.3 1 0 0 1 1 1 1 RNHCP domain zf-C3HC4_4 PF15227.1 KND92134.1 - 0.0025 17.6 8.4 0.0041 16.9 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KND92134.1 - 0.0052 16.3 5.6 0.0091 15.5 3.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KND92134.1 - 0.014 15.0 6.9 0.017 14.8 4.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 KND92134.1 - 0.023 14.7 5.1 0.043 13.9 3.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PolC_DP2 PF03833.8 KND92134.1 - 0.17 9.5 1.4 0.23 9.0 1.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.1 KND92134.1 - 0.18 11.3 8.6 1.2 8.7 6.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KND92134.1 - 2.8 7.9 8.4 2.3e+02 1.8 5.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-MIZ PF02891.15 KND92134.1 - 3.4 7.2 8.3 6.7 6.3 5.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3414 PF11894.3 KND92135.1 - 0 1310.2 0.0 0 1309.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) E2F_TDP PF02319.15 KND92135.1 - 0.17 11.4 0.0 0.66 9.5 0.0 2.0 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Kinetochor_Ybp2 PF08568.5 KND92136.1 - 2.1e-97 326.9 0.0 2.5e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Voltage_CLC PF00654.15 KND92137.1 - 3.5e-91 305.8 22.6 3.5e-91 305.8 15.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 KND92137.1 - 0.013 15.4 3.4 0.013 15.4 2.4 2.5 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Sas10 PF09368.5 KND92138.1 - 8.4e-29 99.5 5.8 8.4e-29 99.5 4.0 2.7 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KND92138.1 - 1.7e-11 44.1 0.0 6.7e-11 42.2 0.0 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Med3 PF11593.3 KND92138.1 - 0.12 11.6 4.5 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Aminotran_3 PF00202.16 KND92140.1 - 1.8e-96 322.9 0.0 2.2e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KND92140.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_22 PF03901.12 KND92141.1 - 5.4e-76 256.2 15.7 7e-76 255.8 10.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 KND92141.1 - 0.052 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) DUF2645 PF10840.3 KND92141.1 - 0.12 12.6 0.3 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) Aminotran_3 PF00202.16 KND92142.1 - 2.2e-106 355.5 0.0 2.7e-106 355.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KND92142.1 - 4.5e-06 26.0 0.0 8.1e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KND92142.1 - 0.0057 15.6 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RhoGAP PF00620.22 KND92144.1 - 1.5e-33 115.5 0.0 3.4e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain BRO1 PF03097.13 KND92145.1 - 4.6e-08 32.2 0.0 6.3e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Brucella_OMP2 PF05244.6 KND92145.1 - 0.09 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Brucella outer membrane protein 2 Tho2 PF11262.3 KND92146.1 - 9.2e-69 231.7 0.0 1.4e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KND92146.1 - 1.3e-26 92.2 0.1 3.7e-26 90.7 0.1 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit ATG16 PF08614.6 KND92147.1 - 0.024 14.4 0.2 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) UvsW PF11637.3 KND92147.1 - 0.076 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW SAS4 PF15460.1 KND92147.1 - 0.077 12.8 1.6 8.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF904 PF06005.7 KND92147.1 - 0.081 13.2 1.5 0.14 12.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF1681 PF07933.9 KND92149.1 - 1.6e-55 187.0 0.0 2.3e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PI-PLC-X PF00388.14 KND92151.1 - 2.6e-12 46.3 0.0 3.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Herpes_LMP1 PF05297.6 KND92152.1 - 2.4 6.9 5.3 4.1 6.2 3.6 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF221 PF02714.10 KND92153.1 - 9.2e-99 330.3 36.4 2e-98 329.2 20.1 2.6 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND92153.1 - 1.6e-39 135.0 2.6 1.6e-39 135.0 1.8 2.8 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KND92153.1 - 1.4e-30 105.0 0.4 3e-30 103.9 0.3 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KND92153.1 - 4.4e-21 75.1 0.0 7.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4381 PF14316.1 KND92154.1 - 0.026 14.6 0.2 0.31 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SIT PF15330.1 KND92154.1 - 0.22 11.6 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Kelch_4 PF13418.1 KND92154.1 - 0.24 11.2 9.1 5.4 6.8 0.2 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain YajC PF02699.10 KND92154.1 - 0.41 10.3 0.0 3.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Trp_oprn_chp PF09534.5 KND92158.1 - 0.19 11.3 1.6 0.31 10.6 1.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SPX PF03105.14 KND92159.1 - 0.043 13.5 6.1 0.095 12.4 4.2 1.5 1 0 0 1 1 1 0 SPX domain WD-3 PF09765.4 KND92159.1 - 0.093 12.0 0.7 0.14 11.3 0.5 1.2 1 0 0 1 1 1 0 WD-repeat region SOBP PF15279.1 KND92159.1 - 3.6 7.8 21.1 1.2 9.4 4.9 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Spc24 PF08286.6 KND92159.1 - 4.7 6.9 7.8 2.4 7.8 3.7 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NDUF_B12 PF08122.7 KND92160.1 - 0.0074 15.9 0.2 0.0074 15.9 0.2 1.8 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family SET PF00856.23 KND92161.1 - 3.1e-20 73.0 0.1 3.1e-20 73.0 0.1 3.4 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KND92161.1 - 7.8e-19 67.4 3.8 2e-18 66.1 2.6 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 KND92161.1 - 0.00012 21.4 0.1 0.00036 19.9 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain VIT1 PF01988.14 KND92161.1 - 0.62 9.5 0.5 1.7 8.0 0.0 1.9 2 0 0 2 2 2 0 VIT family DUF2431 PF10354.4 KND92162.1 - 8.6e-47 159.1 0.0 4.5e-33 114.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 KND92162.1 - 4.6e-05 23.4 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Herpes_LMP1 PF05297.6 KND92162.1 - 1.3 7.8 5.4 2.3 7.0 3.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YihI PF04220.7 KND92162.1 - 2.3 7.5 9.5 5.3 6.3 6.6 1.6 1 0 0 1 1 1 0 Der GTPase activator (YihI) Sds3 PF08598.6 KND92163.1 - 0.5 9.8 5.9 0.11 12.0 0.7 2.2 2 0 0 2 2 2 0 Sds3-like ThiF PF00899.16 KND92164.1 - 2.1e-12 47.0 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Cornichon PF03311.9 KND92164.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Cornichon protein Mhr1 PF12829.2 KND92165.1 - 1.1e-26 92.5 0.0 1.6e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Rhodanese PF00581.15 KND92166.1 - 2.2e-08 34.4 0.0 6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Homeobox PF00046.24 KND92166.1 - 4.8e-08 32.4 0.0 1.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Homeobox domain PIG-X PF08320.7 KND92167.1 - 3.5e-66 222.4 0.0 5.6e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Patatin PF01734.17 KND92169.1 - 8.8e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KND92169.1 - 0.00064 19.3 5.2 0.01 15.4 2.9 2.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND92169.1 - 0.0066 16.4 4.8 0.0066 16.4 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND92169.1 - 0.01 15.7 6.3 0.068 13.0 0.8 2.9 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KND92169.1 - 0.013 15.1 5.2 0.033 13.9 3.3 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KND92169.1 - 0.1 12.4 7.4 0.11 12.3 3.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 KND92169.1 - 0.12 12.1 5.2 0.28 10.8 3.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Use1 PF09753.4 KND92170.1 - 5.4e-07 29.3 0.1 1.3e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Mito_fiss_reg PF05308.6 KND92170.1 - 9.3 5.5 13.3 21 4.3 9.2 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator cwf21 PF08312.7 KND92171.1 - 2e-18 65.9 14.3 5.5e-18 64.5 9.9 1.8 1 0 0 1 1 1 1 cwf21 domain GvpG PF05120.7 KND92171.1 - 0.0023 17.6 6.5 0.036 13.8 1.1 2.3 2 0 0 2 2 2 2 Gas vesicle protein G Sugar_tr PF00083.19 KND92172.1 - 7.4e-12 44.5 0.6 1.2e-11 43.9 0.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_47 PF01532.15 KND92173.1 - 3.5e-164 546.7 0.0 4.1e-164 546.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LON PF02190.11 KND92174.1 - 8.6e-23 81.0 0.0 1.8e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KND92174.1 - 2.6e-10 40.1 22.4 4.8e-08 32.8 7.3 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND92174.1 - 2e-09 36.9 16.9 2.8e-07 30.0 6.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND92174.1 - 2.4e-09 36.7 18.4 9e-08 31.6 4.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND92174.1 - 6.4e-09 35.4 22.5 1.8e-07 30.8 7.8 2.7 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KND92174.1 - 8.1e-09 35.0 20.5 2.1e-06 27.3 6.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND92174.1 - 7.8e-07 28.8 17.9 3.9e-05 23.4 5.3 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND92174.1 - 8.6e-06 25.3 11.3 0.00034 20.2 3.0 3.4 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.1 KND92174.1 - 0.00075 19.0 3.6 0.00075 19.0 2.5 2.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KND92174.1 - 0.011 15.8 3.1 0.011 15.8 2.2 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger zf-P11 PF03854.9 KND92174.1 - 0.012 15.1 7.6 0.025 14.0 3.9 2.4 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.1 KND92174.1 - 0.25 11.1 12.3 0.064 13.0 1.8 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KND92174.1 - 0.62 9.6 12.6 5.4 6.6 4.2 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.27 KND92176.1 - 4.3e-14 51.7 0.1 0.00046 19.9 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat INSIG PF07281.7 KND92177.1 - 1.7e-52 177.5 0.6 2.3e-52 177.1 0.4 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) ABC2_membrane PF01061.19 KND92179.1 - 7.6e-27 93.8 28.9 1.1e-26 93.3 20.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KND92179.1 - 3.2e-24 85.8 0.0 4.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND92179.1 - 4.5e-06 26.8 0.0 0.063 13.2 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND92179.1 - 0.00023 20.6 0.0 0.0095 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KND92179.1 - 0.00028 20.0 0.1 0.00052 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND92179.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 KND92179.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KND92179.1 - 0.0065 16.6 0.0 0.045 13.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND92179.1 - 0.0071 16.4 0.1 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 KND92179.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KND92179.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KND92179.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KND92179.1 - 0.036 12.7 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KND92179.1 - 0.037 14.8 0.0 0.079 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KND92179.1 - 0.042 13.3 0.1 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KND92179.1 - 0.052 13.4 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KND92179.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KND92179.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KND92179.1 - 0.084 12.8 0.1 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 KND92179.1 - 0.094 11.9 0.0 0.35 10.0 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KND92179.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KND92179.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KND92179.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.7 KND92179.1 - 0.25 11.0 2.3 0.63 9.7 0.0 2.6 2 1 0 2 2 2 0 CDR ABC transporter Pkinase PF00069.20 KND92180.1 - 7.9e-39 133.3 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92180.1 - 1.1e-27 96.7 0.0 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND92180.1 - 0.00045 20.0 0.3 1.5 8.4 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KND92180.1 - 0.0022 16.9 0.0 0.0038 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND92180.1 - 0.0041 16.2 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.6 KND92180.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Tim17 PF02466.14 KND92181.1 - 1.7e-26 92.7 3.8 2.5e-26 92.2 2.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LRR_4 PF12799.2 KND92181.1 - 0.11 12.1 0.1 0.32 10.6 0.1 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) PQ-loop PF04193.9 KND92182.1 - 1.6e-34 117.1 17.2 1.5e-18 66.0 0.4 2.7 3 0 0 3 3 3 2 PQ loop repeat TRAM_LAG1_CLN8 PF03798.11 KND92182.1 - 0.075 12.5 1.8 0.069 12.6 0.2 1.8 2 1 0 2 2 2 0 TLC domain AAA PF00004.24 KND92184.1 - 7e-98 323.9 0.0 1.2e-47 161.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KND92184.1 - 1.9e-18 66.1 0.8 5.5e-18 64.7 0.3 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KND92184.1 - 1.5e-13 50.3 0.0 7.8e-06 25.1 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KND92184.1 - 1.7e-13 50.8 0.0 3.1e-07 30.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KND92184.1 - 1e-12 47.9 0.3 1.1e-06 28.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KND92184.1 - 1.5e-12 47.6 0.0 1.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KND92184.1 - 9.4e-12 45.2 0.4 0.0008 19.5 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND92184.1 - 1.6e-11 44.5 0.0 0.00045 20.2 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KND92184.1 - 5.3e-11 43.3 0.0 0.00025 21.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KND92184.1 - 4.2e-09 35.6 0.0 0.0011 17.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KND92184.1 - 2.4e-08 33.6 5.1 0.021 14.2 0.0 4.4 2 2 2 4 4 4 3 AAA domain AAA_14 PF13173.1 KND92184.1 - 4.1e-08 33.1 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KND92184.1 - 5e-08 32.5 0.0 0.006 16.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KND92184.1 - 5.5e-08 32.4 1.9 0.0094 15.6 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain Zeta_toxin PF06414.7 KND92184.1 - 1.9e-07 30.3 0.0 0.0094 15.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KND92184.1 - 2.2e-07 30.2 0.2 0.0064 15.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 KND92184.1 - 6.2e-07 28.9 0.0 1.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 KND92184.1 - 7.1e-07 29.3 0.0 0.03 14.4 0.0 2.8 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 KND92184.1 - 1.5e-06 27.5 0.7 0.26 10.3 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 KND92184.1 - 2.3e-06 27.9 0.0 0.087 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KND92184.1 - 2.7e-06 27.1 0.2 0.11 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 KND92184.1 - 4.5e-06 26.6 0.0 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KND92184.1 - 5.1e-06 26.5 0.0 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 KND92184.1 - 1e-05 24.5 0.1 0.049 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KND92184.1 - 1.5e-05 25.0 0.0 0.058 13.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 KND92184.1 - 1.6e-05 23.9 0.0 0.036 12.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 KND92184.1 - 2.1e-05 24.2 0.1 0.096 12.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 KND92184.1 - 2.5e-05 24.0 0.1 5 6.7 0.0 3.8 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activat PF00158.21 KND92184.1 - 2.6e-05 23.7 0.0 0.21 11.0 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KND92184.1 - 2.8e-05 24.4 0.0 0.25 11.6 0.0 3.6 3 1 0 3 3 2 1 ABC transporter Bac_DnaA PF00308.13 KND92184.1 - 0.00015 21.4 0.0 0.47 10.0 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein PhoH PF02562.11 KND92184.1 - 0.00018 20.8 0.2 0.57 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KND92184.1 - 0.00024 20.7 0.0 0.68 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KND92184.1 - 0.00025 20.6 0.0 0.56 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KND92184.1 - 0.0007 18.5 0.1 0.62 8.8 0.0 2.6 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.1 KND92184.1 - 0.0007 19.2 0.0 0.99 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KND92184.1 - 0.0015 18.2 0.2 0.73 9.5 0.0 3.6 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 KND92184.1 - 0.0021 17.0 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 KND92184.1 - 0.0082 16.0 0.1 0.038 13.8 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.13 KND92184.1 - 0.0094 15.4 0.0 0.32 10.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KND92184.1 - 0.012 14.6 0.4 1.7 7.5 0.0 3.4 2 2 2 4 4 4 0 KAP family P-loop domain IPT PF01745.11 KND92184.1 - 0.014 14.6 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KND92184.1 - 0.023 14.3 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KND92184.1 - 0.037 13.4 0.4 1.8 7.9 0.0 3.3 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 KND92184.1 - 0.063 12.1 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 KND92184.1 - 0.13 12.6 0.1 5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 KND92184.1 - 0.13 11.0 0.0 13 4.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 KND92184.1 - 0.14 12.0 0.1 9.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Zot PF05707.7 KND92184.1 - 0.15 11.5 0.5 18 4.6 0.1 3.5 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) MobB PF03205.9 KND92184.1 - 0.17 11.6 0.9 3.9 7.1 0.0 3.1 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 KND92184.1 - 0.19 10.9 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Rhodanese PF00581.15 KND92185.1 - 1.3e-13 51.2 0.0 5.2e-13 49.3 0.0 2.0 2 1 0 2 2 2 1 Rhodanese-like domain SWIRM PF04433.12 KND92185.1 - 6.4e-12 45.4 0.0 2.2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KND92185.1 - 1.1e-09 37.6 3.9 2.2e-09 36.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KND92185.1 - 9.6e-07 28.7 0.2 8e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 Myb-like DNA-binding domain ABC_tran PF00005.22 KND92186.1 - 4.7e-16 59.3 0.0 1.6e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 KND92186.1 - 0.0003 20.5 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase SMC_N PF02463.14 KND92186.1 - 0.00035 19.8 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND92186.1 - 0.0036 17.3 0.0 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND92186.1 - 0.0085 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KND92186.1 - 0.02 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KND92186.1 - 0.028 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KND92186.1 - 0.028 14.0 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 KND92186.1 - 0.033 13.6 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KND92186.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KND92186.1 - 0.076 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KND92186.1 - 0.089 12.9 0.1 0.27 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KND92186.1 - 0.095 13.5 0.0 0.23 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KND92186.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KND92186.1 - 0.16 12.4 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KND92186.1 - 0.2 11.4 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Dynamin family Rad17 PF03215.10 KND92186.1 - 0.44 9.1 0.1 1.3 7.6 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DPPIV_N PF00930.16 KND92189.1 - 1.8e-81 273.5 0.2 1e-41 142.7 0.0 2.2 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KND92189.1 - 5.4e-55 185.8 1.1 1.1e-54 184.9 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND92189.1 - 2e-09 37.3 2.4 6.7e-09 35.6 0.9 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND92189.1 - 1.6e-05 24.9 5.5 0.0002 21.3 3.8 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KND92189.1 - 0.0014 18.1 0.6 0.045 13.1 0.2 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Apc4_WD40 PF12894.2 KND92189.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1640 PF07798.6 KND92190.1 - 4.3e-62 209.2 7.1 4.3e-62 209.2 4.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) 2-Hacid_dh_C PF02826.14 KND92190.1 - 3.8e-53 179.2 0.0 8.4e-53 178.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND92190.1 - 3.8e-18 65.2 0.0 7.6e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KND92190.1 - 0.0058 16.4 0.3 0.057 13.2 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Lzipper-MIP1 PF14389.1 KND92190.1 - 0.063 13.3 3.4 9.9 6.3 1.1 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 cwf21 PF08312.7 KND92190.1 - 0.13 12.0 2.6 0.36 10.7 1.8 1.7 1 1 0 1 1 1 0 cwf21 domain Syntaxin PF00804.20 KND92190.1 - 0.3 11.2 6.0 1.5 9.0 4.1 2.1 1 1 0 1 1 1 0 Syntaxin MFS_1 PF07690.11 KND92191.1 - 1e-05 24.4 10.0 4.8e-05 22.2 7.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily JAB PF01398.16 KND92193.1 - 6e-08 32.4 0.7 2e-07 30.7 0.5 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 KND92193.1 - 0.032 13.4 1.4 3.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal AdoHcyase PF05221.12 KND92194.1 - 5.5e-135 448.5 0.2 6.4e-135 448.2 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KND92194.1 - 7.4e-84 279.5 2.0 1.1e-83 278.9 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KND92194.1 - 3.9e-06 26.1 0.2 8.4e-06 25.0 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KND92194.1 - 0.0046 16.5 0.1 0.0086 15.6 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 KND92194.1 - 0.014 14.7 0.4 0.025 13.9 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KND92194.1 - 0.054 13.4 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KND92194.1 - 0.076 12.6 0.5 0.14 11.7 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2196 PF09962.4 KND92195.1 - 2.3e-22 78.5 0.9 3.1e-22 78.1 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.7 KND92195.1 - 0.031 14.4 0.8 0.044 13.9 0.6 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KND92195.1 - 0.054 13.7 0.1 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 C2H2-type zinc-finger domain AMP-binding PF00501.23 KND92195.1 - 0.14 10.4 0.2 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 AMP-binding enzyme GAGA PF09237.6 KND92195.1 - 0.19 11.3 0.1 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 GAGA factor Peptidase_M43 PF05572.8 KND92196.1 - 8e-18 64.5 1.7 1.3e-17 63.8 0.6 1.8 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KND92196.1 - 3.7e-07 30.2 0.6 8e-07 29.1 0.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KND92196.1 - 7.7e-07 29.3 1.7 1e-06 28.8 1.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KND92196.1 - 6.9e-05 23.3 1.6 0.00019 21.9 1.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KND92196.1 - 0.00017 21.3 0.6 0.00037 20.2 0.4 1.6 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 KND92196.1 - 0.003 17.1 0.9 0.0043 16.6 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KND92196.1 - 0.014 15.1 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Matrixin ECH PF00378.15 KND92197.1 - 1.1e-11 44.3 0.0 1.2e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 KND92198.1 - 5.3e-27 94.4 0.4 8.7e-27 93.7 0.3 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family KTI12 PF08433.5 KND92199.1 - 4.2e-68 229.4 0.0 8.2e-68 228.5 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KND92199.1 - 0.0002 22.1 0.0 0.00037 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND92199.1 - 0.00031 20.6 0.3 0.001 18.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain CPT PF07931.7 KND92199.1 - 0.0033 17.0 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KND92199.1 - 0.0041 17.4 0.0 0.012 15.8 0.0 1.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KND92199.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KND92199.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND92199.1 - 0.048 13.6 0.1 0.35 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Glyco_hydro_12 PF01670.11 KND92199.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 Mitochondr_Som1 PF11093.3 KND92200.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial export protein Som1 AAA_2 PF07724.9 KND92201.1 - 5e-47 159.9 0.0 4.1e-45 153.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KND92201.1 - 1.3e-27 96.5 0.0 7.4e-15 55.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KND92201.1 - 6.2e-22 77.3 0.9 6.2e-22 77.3 0.6 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KND92201.1 - 1.6e-16 60.8 14.0 3.1e-06 27.2 0.0 6.5 3 2 1 6 6 5 2 AAA ATPase domain AAA_5 PF07728.9 KND92201.1 - 5.5e-16 58.5 0.0 2.1e-10 40.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND92201.1 - 2.4e-13 50.3 0.2 4.1e-05 23.7 0.0 4.0 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KND92201.1 - 4e-09 36.1 0.0 6.2e-06 25.7 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KND92201.1 - 1.2e-08 35.7 7.1 0.0086 16.8 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KND92201.1 - 1.8e-07 31.4 2.2 0.0089 16.3 0.0 4.2 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KND92201.1 - 1.9e-07 31.0 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KND92201.1 - 4.3e-07 29.5 1.4 0.044 13.5 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 KND92201.1 - 1.9e-06 27.4 0.0 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Clp_N PF02861.15 KND92201.1 - 1.6e-05 24.7 4.4 0.03 14.2 0.1 4.6 4 0 0 4 4 4 1 Clp amino terminal domain AAA_28 PF13521.1 KND92201.1 - 1.8e-05 24.7 0.0 0.26 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KND92201.1 - 2.6e-05 24.1 0.0 0.19 11.5 0.0 3.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KND92201.1 - 3.3e-05 23.1 0.2 0.19 10.8 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KND92201.1 - 3.8e-05 23.4 10.9 0.012 15.3 0.6 5.5 3 2 0 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 KND92201.1 - 6.8e-05 22.4 0.1 0.61 9.6 0.0 3.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KND92201.1 - 6.9e-05 22.9 0.0 0.47 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.1 KND92201.1 - 8.2e-05 23.0 3.0 1.9 8.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KND92201.1 - 0.00011 21.2 0.9 0.0067 15.3 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KND92201.1 - 0.00017 21.0 0.6 1.4 8.2 0.0 3.8 3 1 1 4 4 4 2 AAA domain MobB PF03205.9 KND92201.1 - 0.0002 21.0 0.0 0.87 9.2 0.0 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 KND92201.1 - 0.00024 21.0 0.0 0.1 12.4 0.0 3.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KND92201.1 - 0.00032 20.3 0.2 0.6 9.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 KND92201.1 - 0.00062 18.9 0.0 0.32 10.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KND92201.1 - 0.00074 19.8 0.5 1.1 9.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 KND92201.1 - 0.0013 18.2 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KND92201.1 - 0.0016 17.9 6.4 0.7 9.2 0.0 5.2 4 2 2 6 6 6 1 AAA-like domain NACHT PF05729.7 KND92201.1 - 0.0032 17.1 0.0 0.53 9.9 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Torsin PF06309.6 KND92201.1 - 0.0036 17.1 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Torsin NTPase_1 PF03266.10 KND92201.1 - 0.0072 16.0 0.3 0.62 9.7 0.0 3.6 4 0 0 4 4 4 1 NTPase KTI12 PF08433.5 KND92201.1 - 0.0075 15.5 0.9 9.1 5.4 0.0 3.5 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_21 PF13304.1 KND92201.1 - 0.012 15.5 0.3 2.6 7.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain UPF0079 PF02367.12 KND92201.1 - 0.028 14.0 0.0 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 V_ATPase_I PF01496.14 KND92201.1 - 0.029 12.2 1.8 0.045 11.6 1.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1640 PF07798.6 KND92201.1 - 0.046 13.7 5.8 0.11 12.5 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) MMR_HSR1 PF01926.18 KND92201.1 - 0.076 12.9 0.0 1.3 9.0 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND92201.1 - 0.083 12.4 0.0 9.7 5.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Noelin-1 PF12308.3 KND92201.1 - 0.12 12.2 3.6 0.49 10.2 2.1 2.4 1 1 0 1 1 1 0 Neurogenesis glycoprotein OEP PF02321.13 KND92201.1 - 0.31 10.5 10.9 0.73 9.3 7.6 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein IncA PF04156.9 KND92201.1 - 7.9 6.0 10.2 19 4.7 7.1 1.6 1 0 0 1 1 1 0 IncA protein CYSTM PF12734.2 KND92202.1 - 9.8 6.3 25.5 14 5.8 17.7 1.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Zn_clus PF00172.13 KND92203.1 - 1.9e-09 37.2 6.8 1.9e-09 37.2 4.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND92203.1 - 3.1e-07 29.5 0.0 1.2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain HeLo PF14479.1 KND92204.1 - 1.6e-45 155.5 3.0 2.5e-45 154.8 2.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KND92204.1 - 1.4e-05 24.2 0.1 4.9e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND92204.1 - 5.3e-05 22.4 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HCMV_UL139 PF12507.3 KND92204.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein APH PF01636.18 KND92205.1 - 3.1e-08 33.6 0.0 1e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND92205.1 - 1.5e-07 31.2 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase adh_short PF00106.20 KND92206.1 - 6.3e-13 48.9 3.5 1.1e-12 48.1 2.3 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND92206.1 - 2e-07 30.8 0.7 2e-07 30.8 0.5 2.3 2 1 1 3 3 3 1 KR domain NAD_binding_10 PF13460.1 KND92206.1 - 2.7e-06 27.5 1.4 4.2e-06 26.8 0.3 1.9 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KND92206.1 - 5.7e-06 25.7 3.9 1e-05 24.9 2.7 1.4 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 KND92206.1 - 2.2e-05 24.1 2.7 0.0017 18.1 0.2 2.4 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KND92206.1 - 0.00019 21.2 0.1 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KND92206.1 - 0.0029 17.0 1.0 0.0046 16.4 0.2 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KND92206.1 - 0.016 15.1 0.8 0.026 14.4 0.2 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KND92206.1 - 0.027 13.3 0.5 0.16 10.7 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KND92206.1 - 0.08 12.5 1.3 0.15 11.6 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydro_lipase PF04083.11 KND92207.1 - 1.1e-20 72.7 0.6 1.9e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KND92207.1 - 8.7e-06 25.7 0.5 1.3e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92207.1 - 0.0021 17.7 0.0 0.0057 16.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1049 PF06305.6 KND92207.1 - 0.17 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) AAA PF00004.24 KND92208.1 - 3e-51 173.0 0.0 1.4e-43 148.2 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND92208.1 - 1.1e-06 29.5 0.0 0.00049 20.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND92208.1 - 1.3e-05 24.6 0.1 0.00049 19.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KND92208.1 - 0.00031 19.8 0.0 0.0007 18.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND92208.1 - 0.00047 20.1 1.8 0.025 14.5 0.0 3.7 3 1 1 4 4 3 1 AAA ATPase domain Parvo_NS1 PF01057.12 KND92208.1 - 0.00068 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KND92208.1 - 0.00069 19.7 0.1 0.005 16.9 0.0 2.4 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KND92208.1 - 0.0011 18.3 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KND92208.1 - 0.0024 17.6 0.1 0.019 14.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 KND92208.1 - 0.0026 17.9 0.0 0.036 14.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 KND92208.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KND92208.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 KND92208.1 - 0.014 15.1 0.0 0.078 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KND92208.1 - 0.022 13.9 0.1 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KND92208.1 - 0.024 14.5 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KND92208.1 - 0.029 14.2 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KND92208.1 - 0.034 13.3 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KND92208.1 - 0.041 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KND92208.1 - 0.089 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KND92208.1 - 0.16 11.5 0.2 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KND92208.1 - 0.33 9.5 0.0 0.54 8.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase MMS19_N PF14500.1 KND92209.1 - 8.6e-46 156.3 0.1 2.4e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KND92209.1 - 4.6e-11 42.1 0.0 3.2e-10 39.3 0.0 2.4 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal AMP-binding PF00501.23 KND92210.1 - 2.3e-95 319.4 0.0 2.7e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND92210.1 - 2.2e-10 41.2 0.1 5.5e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.6 KND92211.1 - 4.3e-85 285.4 0.0 5e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Ribonuclease_T2 PF00445.13 KND92212.1 - 9.5e-47 159.0 2.2 1.3e-46 158.6 1.5 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SH3BGR PF04908.10 KND92213.1 - 5.5e-05 23.0 0.1 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein RNase_P_pop3 PF08228.6 KND92215.1 - 9.4e-07 28.7 0.0 0.00026 20.8 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 NOC3p PF07540.6 KND92216.1 - 1.3e-32 111.9 0.6 9.6e-31 105.9 0.2 3.1 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 KND92216.1 - 9.3e-27 93.4 0.8 2.5e-26 92.0 0.2 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Brix PF04427.13 KND92217.1 - 6e-40 136.9 0.3 8.6e-40 136.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain Sporozoite_P67 PF05642.6 KND92217.1 - 0.021 12.7 2.0 0.028 12.2 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KND92217.1 - 2.9 5.7 24.3 3.9 5.2 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family TPT PF03151.11 KND92218.1 - 5.3e-16 58.6 31.8 4.2e-15 55.6 9.1 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KND92218.1 - 6.1e-05 23.0 11.5 6.1e-05 23.0 8.0 3.3 2 2 2 4 4 4 1 EamA-like transporter family Tuberculin PF12198.3 KND92218.1 - 0.29 11.0 0.1 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 Theoretical tuberculin protein EmrE PF13536.1 KND92218.1 - 3.2 7.9 36.1 0.088 13.0 5.9 3.4 3 1 1 4 4 4 0 Multidrug resistance efflux transporter PRCC PF10253.4 KND92219.1 - 1.9e-38 132.9 5.2 1.9e-38 132.9 3.6 2.8 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF3123 PF11321.3 KND92219.1 - 7.7 6.8 12.7 0.066 13.5 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) UCH PF00443.24 KND92221.1 - 1.5e-43 148.8 0.1 2.8e-43 147.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KND92221.1 - 2.3e-18 65.8 0.0 5.2e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 KND92221.1 - 8.7e-16 58.2 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CTP_synth_N PF06418.9 KND92222.1 - 5.4e-117 389.7 2.0 6.6e-117 389.5 1.0 1.4 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.23 KND92222.1 - 5.7e-54 182.4 0.0 9.4e-54 181.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KND92222.1 - 1.9e-07 30.7 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KND92222.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Syntaxin PF00804.20 KND92223.1 - 0.0038 17.3 0.1 0.0063 16.6 0.1 1.3 1 0 0 1 1 1 1 Syntaxin DUF3437 PF11919.3 KND92223.1 - 0.056 13.1 0.6 0.58 9.9 0.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3437) UPF0118 PF01594.11 KND92223.1 - 0.19 10.7 1.5 2.4 7.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF20 ICAT PF06384.6 KND92223.1 - 0.5 10.1 2.2 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 Beta-catenin-interacting protein ICAT SIN1 PF05422.7 KND92224.1 - 1.7e-38 132.4 0.1 5.2e-18 64.8 0.0 3.3 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KND92224.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG GTP_cyclohydro2 PF00925.15 KND92224.1 - 0.022 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II RBD PF02196.10 KND92224.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain TGT PF01702.13 KND92225.1 - 8.1e-88 293.7 0.0 1e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase AAA_7 PF12775.2 KND92226.1 - 0.21 10.6 0.2 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Pyridoxal_deC PF00282.14 KND92227.1 - 2.2e-76 256.7 0.0 2.7e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KND92227.1 - 1.4e-06 27.6 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KND92227.1 - 0.0011 17.7 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Thioesterase PF00975.15 KND92228.1 - 8.2e-12 45.8 0.0 1.4e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KND92228.1 - 5.9e-06 26.3 0.1 6.9e-06 26.0 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92228.1 - 0.044 13.5 0.0 0.046 13.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND92228.1 - 0.07 12.6 0.3 0.087 12.3 0.2 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold bZIP_1 PF00170.16 KND92229.1 - 1.8e-05 24.5 4.6 3.8e-05 23.5 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND92229.1 - 0.019 14.7 4.2 0.039 13.7 2.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper ABC_tran PF00005.22 KND92231.1 - 4.3e-49 166.3 0.7 3.5e-26 92.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KND92231.1 - 1.3e-28 100.0 29.1 1.6e-17 63.6 10.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KND92231.1 - 2.1e-21 77.1 1.9 3.5e-05 23.9 0.0 4.3 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 KND92231.1 - 3e-10 39.4 0.1 0.0013 18.2 0.2 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 KND92231.1 - 7.4e-07 28.6 5.5 0.28 10.4 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KND92231.1 - 5.1e-05 22.5 0.2 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KND92231.1 - 6.7e-05 23.3 5.7 0.037 14.3 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KND92231.1 - 8.5e-05 21.7 0.0 0.42 9.6 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 KND92231.1 - 0.00097 18.5 0.1 2.2 7.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KND92231.1 - 0.0013 18.7 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 KND92231.1 - 0.01 15.7 0.2 1.4 8.9 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KND92231.1 - 0.026 14.6 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KND92231.1 - 0.038 13.9 0.3 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KND92231.1 - 0.043 13.5 3.8 16 5.2 0.1 3.9 3 0 0 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 KND92231.1 - 0.056 13.0 1.2 5.4 6.5 0.0 2.9 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KND92231.1 - 0.065 12.3 0.1 2.3 7.2 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.1 KND92231.1 - 0.098 12.5 0.5 38 4.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KND92231.1 - 0.11 12.2 1.0 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KND92231.1 - 0.21 10.9 0.7 17 4.7 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.17 KND92231.1 - 0.25 10.7 1.2 15 4.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 KND92231.1 - 0.44 8.9 0.1 6.2 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 KND92231.1 - 0.72 8.4 0.1 4.7 5.8 0.1 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Hist_deacetyl PF00850.14 KND92232.1 - 1.6e-62 211.6 0.0 2.3e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.14 KND92233.1 - 8.5e-09 35.4 0.0 1.8e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 PHP domain HAD_2 PF13419.1 KND92234.1 - 5.7e-31 108.0 0.0 7.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND92234.1 - 0.0033 17.8 0.0 0.011 16.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DFP PF04127.10 KND92234.1 - 0.0043 16.6 0.0 0.91 9.1 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DUF4047 PF13256.1 KND92234.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Solute_trans_a PF03619.11 KND92235.1 - 1.6e-76 257.2 21.2 1.9e-76 257.0 14.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha VirB8 PF04335.8 KND92235.1 - 0.15 11.6 0.5 0.29 10.6 0.1 1.6 2 0 0 2 2 2 0 VirB8 protein WSC PF01822.14 KND92236.1 - 4.1e-12 45.8 9.8 4.1e-12 45.8 6.8 2.0 2 0 0 2 2 2 1 WSC domain DUF4366 PF14283.1 KND92236.1 - 0.0071 15.8 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) TMEM154 PF15102.1 KND92236.1 - 0.014 15.0 1.3 0.073 12.7 0.9 2.1 1 1 0 1 1 1 0 TMEM154 protein family MgtE PF01769.11 KND92236.1 - 0.016 15.5 1.5 0.12 12.7 0.1 2.5 2 0 0 2 2 2 0 Divalent cation transporter Podoplanin PF05808.6 KND92236.1 - 0.025 14.1 8.2 0.043 13.3 5.7 1.3 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.5 KND92236.1 - 0.067 12.5 1.9 0.26 10.6 1.3 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain P12 PF12669.2 KND92236.1 - 0.27 11.4 1.7 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Gram_pos_anchor PF00746.16 KND92236.1 - 0.33 10.8 3.3 1.5 8.7 2.3 2.2 1 0 0 1 1 1 0 Gram positive anchor Afaf PF15339.1 KND92237.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor TRAM_LAG1_CLN8 PF03798.11 KND92238.1 - 7.6e-35 120.2 13.7 1.3e-34 119.5 9.5 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KND92238.1 - 6.6e-24 83.1 0.0 1.8e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein DUF605 PF04652.11 KND92240.1 - 6.4 6.0 18.0 12 5.1 12.5 1.4 1 0 0 1 1 1 0 Vta1 like Paired_CXXCH_1 PF09699.5 KND92241.1 - 0.79 9.2 4.1 0.35 10.4 1.1 1.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Sugar_tr PF00083.19 KND92242.1 - 3.2e-39 134.7 15.1 1.2e-38 132.8 10.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND92242.1 - 4.5e-16 58.4 25.0 1.2e-15 57.0 17.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 KND92243.1 - 4.4e-43 147.4 0.1 8.3e-23 81.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND92243.1 - 5.4e-11 42.8 1.0 3.5e-10 40.1 0.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sulfotransfer_3 PF13469.1 KND92244.1 - 0.00042 21.2 0.1 0.0011 19.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF1814 PF08843.6 KND92247.1 - 0.012 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) DEDD_Tnp_IS110 PF01548.12 KND92247.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Transposase Methyltransf_2 PF00891.13 KND92248.1 - 3e-29 101.9 0.0 4.1e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase NYN PF01936.13 KND92250.1 - 0.017 15.4 0.1 0.04 14.1 0.1 1.7 1 1 0 1 1 1 0 NYN domain DUF3435 PF11917.3 KND92251.1 - 0.0099 14.6 0.0 0.0099 14.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) 2OG-Fe_Oxy_2 PF10014.4 KND92252.1 - 2.6e-46 157.4 1.1 2.6e-46 157.4 0.8 1.4 2 0 0 2 2 2 1 2OG-Fe dioxygenase AMP-binding PF00501.23 KND92253.1 - 5.8e-66 222.6 0.0 7.5e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND92253.1 - 1.2e-14 54.9 0.1 3.1e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldolase_II PF00596.16 KND92254.1 - 1e-41 142.5 0.0 1.4e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LEA_1 PF03760.10 KND92255.1 - 7 6.8 6.3 62 3.8 0.1 3.2 2 1 1 3 3 3 0 Late embryogenesis abundant (LEA) group 1 PI-PLC-X PF00388.14 KND92256.1 - 5.1e-10 38.9 0.0 7.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_2_C PF02836.12 KND92256.1 - 0.0087 14.9 0.0 2.7 6.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain APH PF01636.18 KND92257.1 - 1.3e-08 34.8 0.1 3e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND92257.1 - 0.0027 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND92257.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KND92257.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase Hpt PF01627.18 KND92258.1 - 2.1e-12 46.8 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Catalase-rel PF06628.7 KND92258.1 - 0.055 13.3 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Catalase-related immune-responsive Sad1_UNC PF07738.8 KND92259.1 - 7.7e-06 25.7 0.0 0.0042 16.8 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF4217 PF13959.1 KND92260.1 - 6.8e-22 76.7 0.0 1.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 KND92261.1 - 4.2e-44 150.0 0.0 7.2e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND92261.1 - 1e-22 79.7 0.0 2.2e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND92261.1 - 6e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KND92261.1 - 0.077 12.0 7.2 0.63 9.0 0.0 2.8 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 KND92261.1 - 0.12 12.5 0.6 0.69 10.0 0.2 2.5 2 1 0 2 2 2 0 AAA domain RGS PF00615.14 KND92262.1 - 0.00059 19.9 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain ECH PF00378.15 KND92263.1 - 5.9e-35 120.5 0.1 6.6e-35 120.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Epimerase PF01370.16 KND92264.1 - 1.9e-15 56.9 0.6 4e-15 55.8 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND92264.1 - 8.8e-10 38.8 2.4 5.9e-09 36.1 1.7 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND92264.1 - 1.1e-05 24.3 0.4 1.3e-05 24.0 0.3 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND92264.1 - 0.0025 16.7 1.1 0.014 14.3 0.8 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KND92264.1 - 0.031 13.5 0.4 0.052 12.7 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KND92264.1 - 0.038 13.3 3.3 0.54 9.6 2.3 2.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NUC153 PF08159.7 KND92265.1 - 5.9e-14 51.3 0.6 5.9e-14 51.3 0.4 3.3 4 0 0 4 4 4 2 NUC153 domain AMP-binding PF00501.23 KND92266.1 - 5e-73 245.8 0.3 1e-72 244.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme DUF3902 PF13042.1 KND92266.1 - 0.085 12.1 0.5 0.17 11.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) SPC12 PF06645.8 KND92266.1 - 0.21 11.3 3.3 0.095 12.5 0.3 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Zn_clus PF00172.13 KND92267.1 - 0.0016 18.2 9.7 0.0045 16.8 6.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KND92268.1 - 4.2e-149 496.8 0.0 6.5e-149 496.1 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KND92268.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Metallophos PF00149.23 KND92269.1 - 3.9e-14 52.5 0.5 6e-14 51.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EBP PF05241.7 KND92270.1 - 1.8e-47 160.9 10.0 8.6e-47 158.6 6.9 1.8 1 1 0 1 1 1 1 Emopamil binding protein Nup88 PF10168.4 KND92271.1 - 3.6e-07 28.4 3.9 0.0096 13.8 1.8 2.9 3 0 0 3 3 3 2 Nuclear pore component WD40 PF00400.27 KND92271.1 - 0.0031 17.3 0.8 0.031 14.1 0.3 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF1090 PF06476.7 KND92271.1 - 0.55 9.9 7.7 0.11 12.1 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF4407 PF14362.1 KND92271.1 - 2.5 6.9 7.6 4.3 6.2 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.17 KND92272.1 - 3.6e-16 58.5 0.0 5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND92272.1 - 9.7e-13 47.9 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND92272.1 - 1.1e-08 34.7 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.4 KND92273.1 - 5.1e-46 154.9 1.4 5.7e-46 154.8 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone PF00125.19 KND92275.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KND92275.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KND92275.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KND92275.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KND92275.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KND92275.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Aminotran_1_2 PF00155.16 KND92276.1 - 7.7e-38 130.3 0.0 1.2e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND92276.1 - 1.1e-06 27.2 0.0 1.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KND92276.1 - 0.00034 19.8 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KND92276.1 - 0.00059 18.6 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Mannitol_dh_C PF08125.8 KND92277.1 - 1.7e-45 155.1 0.3 1.7e-45 155.1 0.2 1.5 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KND92277.1 - 4.4e-19 68.9 0.2 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KND92277.1 - 0.0069 15.7 0.1 0.017 14.4 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PGI PF00342.14 KND92278.1 - 5.9e-207 687.8 0.2 7.3e-207 687.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase_C PF00433.19 KND92278.1 - 0.068 13.7 0.3 0.26 11.8 0.2 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 KND92279.1 - 2.6e-08 33.9 0.1 3.3e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND92279.1 - 5.2e-05 22.4 0.1 5.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND92279.1 - 6.6e-05 22.1 0.0 7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1679 PF07914.6 KND92279.1 - 0.00074 18.2 0.0 0.00083 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.17 KND92279.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KND92279.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1353 PF07087.6 KND92279.1 - 0.068 12.6 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1353) Ribosomal_S21 PF01165.15 KND92280.1 - 7.4e-08 31.7 6.2 1.1e-07 31.1 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 HAUS6_N PF14661.1 KND92281.1 - 2.2e-61 207.3 0.2 4.9e-61 206.2 0.1 1.6 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF4419 PF14388.1 KND92282.1 - 1.2e-78 264.3 0.0 1.4e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Acetyltransf_6 PF13480.1 KND92282.1 - 0.035 14.0 0.6 0.081 12.8 0.4 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSDR_N_2 PF13588.1 KND92283.1 - 0.1 12.4 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Glyco_hydro_35 PF01301.14 KND92283.1 - 0.11 11.7 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 Coatomer_WDAD PF04053.9 KND92284.1 - 9.3e-168 558.5 0.0 2e-167 557.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KND92284.1 - 7.5e-48 158.7 11.4 2e-10 40.1 0.1 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 KND92284.1 - 4.4e-05 21.8 3.0 0.0049 15.0 0.0 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KND92284.1 - 0.0018 18.0 0.0 4.2 7.1 0.0 3.4 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Vps54 PF07928.7 KND92285.1 - 2.8e-42 144.0 0.0 6.7e-42 142.8 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 KND92285.1 - 0.00027 19.9 1.1 0.00027 19.9 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KND92285.1 - 0.004 15.8 2.3 0.55 8.8 0.0 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF2451 PF10474.4 KND92285.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) DSPc PF00782.15 KND92287.1 - 9.4e-09 34.9 0.0 2.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KND92287.1 - 0.0045 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 KND92287.1 - 0.036 12.9 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase DUF2375 PF09558.5 KND92287.1 - 0.091 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Ribonuclease_3 PF00636.21 KND92288.1 - 1.8e-44 150.8 0.1 5.3e-21 75.1 0.0 3.7 4 0 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KND92288.1 - 1.2e-28 99.6 0.0 4.8e-14 52.4 0.0 3.7 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.26 KND92288.1 - 2.4e-16 59.3 0.1 1.1e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KND92288.1 - 4.3e-16 58.4 0.1 1.8e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.24 KND92288.1 - 1.5e-14 53.8 0.0 7.3e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KND92288.1 - 2e-12 47.3 0.1 6.7e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mqo PF06039.10 KND92288.1 - 0.00048 18.4 0.0 0.024 12.8 0.0 2.3 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) SNF2_N PF00176.18 KND92288.1 - 0.00054 18.8 0.0 0.0015 17.3 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KND92288.1 - 0.063 13.4 0.1 0.54 10.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain dsrm PF00035.20 KND92288.1 - 0.083 13.4 0.2 0.57 10.8 0.0 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif Mmp37 PF09139.6 KND92289.1 - 9.6e-128 425.8 0.0 1.2e-127 425.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAD PF05557.8 KND92290.1 - 6.9e-54 183.1 59.3 1e-53 182.5 41.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Bcr-Abl_Oligo PF09036.5 KND92290.1 - 0.008 16.1 0.8 0.008 16.1 0.5 3.8 2 1 1 3 3 3 1 Bcr-Abl oncoprotein oligomerisation domain Hydantoinase_B PF02538.9 KND92290.1 - 1.4 7.0 4.5 2.8 6.0 2.1 2.1 1 1 1 2 2 2 0 Hydantoinase B/oxoprolinase Cation_efflux PF01545.16 KND92291.1 - 4.1e-26 91.7 1.9 6.3e-26 91.1 1.3 1.3 1 0 0 1 1 1 1 Cation efflux family DUF3275 PF11679.3 KND92291.1 - 2.6 7.6 5.8 4.2 6.9 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) NACHT PF05729.7 KND92293.1 - 1.2e-12 47.7 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KND92293.1 - 9.7e-06 25.7 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND92293.1 - 1.3e-05 25.3 0.0 3.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.6 KND92293.1 - 0.0077 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Torsin DUF2075 PF09848.4 KND92293.1 - 0.045 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TraC_F_IV PF11130.3 KND92293.1 - 0.072 12.5 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer KAP_NTPase PF07693.9 KND92293.1 - 0.092 11.7 0.2 5.2 5.9 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Cwf_Cwc_15 PF04889.7 KND92294.1 - 2.2e-71 240.4 26.2 4.8e-70 236.0 18.2 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 KND92294.1 - 0.16 11.9 14.0 0.32 11.0 9.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Myc_N PF01056.13 KND92294.1 - 1.4 8.0 8.3 2 7.4 5.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 KND92294.1 - 2.2 7.1 8.3 3.3 6.6 5.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tom37_C PF11801.3 KND92294.1 - 2.9 7.7 8.5 1.7 8.4 4.5 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Pox_RNA_Pol_19 PF05320.7 KND92294.1 - 5.6 6.6 11.3 9.9 5.8 7.2 1.8 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YqfQ PF14181.1 KND92294.1 - 6.7 6.7 6.7 18 5.3 4.7 1.7 1 0 0 1 1 1 0 YqfQ-like protein FGGY_C PF02782.11 KND92295.1 - 7.5e-21 74.6 0.0 1.4e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KND92295.1 - 3.6e-15 55.9 0.0 6.2e-06 25.6 0.0 3.6 2 2 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 KND92296.1 - 1.6e-24 86.4 0.0 1.8e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Cation efflux family Arf PF00025.16 KND92297.1 - 7.3e-40 136.0 0.0 1.2e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KND92297.1 - 6.8e-14 51.3 0.0 4.7e-09 35.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KND92297.1 - 4.4e-08 32.5 0.0 5.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KND92297.1 - 5.1e-08 32.4 0.0 1.1e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 KND92297.1 - 1.7e-07 30.6 0.0 3.6e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KND92297.1 - 0.00013 21.4 0.0 0.0004 19.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KND92297.1 - 0.00035 21.0 0.0 0.001 19.5 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KND92297.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.16 KND92298.1 - 3e-18 66.4 0.0 4.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KND92298.1 - 1.2e-08 34.7 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glyco_hydro_18 PF00704.23 KND92299.1 - 6.2e-47 160.7 5.2 7.5e-47 160.4 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 KND92300.1 - 3.3e-27 94.6 0.0 5.6e-14 52.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND92300.1 - 1e-21 75.5 0.0 1.2e-08 34.3 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KND92300.1 - 2e-21 75.9 0.3 9.2e-08 32.4 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND92300.1 - 1.7e-20 72.5 0.1 2.4e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND92300.1 - 6.7e-16 56.8 0.0 4.6e-05 23.2 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat DUF1771 PF08590.5 KND92301.1 - 2e-24 85.3 8.8 2e-24 85.3 6.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KND92301.1 - 1.7e-13 50.5 1.4 4.5e-13 49.2 0.3 2.3 2 0 0 2 2 2 1 Smr domain DUF4407 PF14362.1 KND92301.1 - 0.77 8.6 6.2 0.46 9.3 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) G-alpha PF00503.15 KND92302.1 - 2e-131 438.2 0.9 2.6e-131 437.8 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KND92302.1 - 9.8e-15 54.2 2.0 5.7e-10 38.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KND92302.1 - 0.00021 20.7 0.1 0.00046 19.6 0.1 1.5 1 0 0 1 1 1 1 CHC2 zinc finger Miro PF08477.8 KND92302.1 - 0.0042 17.5 0.1 3 8.3 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KND92302.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KND92302.1 - 0.019 14.1 2.3 1.2 8.2 0.0 2.5 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND92302.1 - 0.047 13.1 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 KND92302.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KND92302.1 - 0.14 12.1 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3716 PF12511.3 KND92303.1 - 1.1e-09 37.7 0.4 2e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DSPc PF00782.15 KND92304.1 - 1e-10 41.2 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain UPF0121 PF03661.8 KND92304.1 - 1e-09 37.9 0.1 1.5e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Y_phosphatase PF00102.22 KND92304.1 - 0.0095 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KND92304.1 - 0.039 14.1 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KND92304.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.27 KND92305.1 - 5.2e-78 254.3 14.8 9.3e-12 44.3 1.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KND92305.1 - 0.00064 17.9 4.7 0.055 11.5 0.2 3.8 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KND92305.1 - 0.0036 16.1 0.1 1.6 7.3 0.0 2.7 2 1 1 3 3 3 2 Nup133 N terminal like TAF8_C PF10406.4 KND92305.1 - 0.14 12.1 0.5 0.35 10.9 0.4 1.6 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term LisH PF08513.6 KND92306.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 LisH DUF3632 PF12311.3 KND92307.1 - 2.6e-31 108.8 0.0 3.5e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Peptidase_S10 PF00450.17 KND92309.1 - 4.4e-79 266.5 0.0 1.1e-78 265.2 0.0 1.7 2 1 0 2 2 2 1 Serine carboxypeptidase Peptidase_M28 PF04389.12 KND92311.1 - 9.8e-35 119.9 0.2 1.5e-33 116.0 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KND92311.1 - 0.033 13.6 0.0 0.098 12.1 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 DUF3328 PF11807.3 KND92312.1 - 6.9e-32 110.8 0.6 9.9e-32 110.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Herpes_gE PF02480.11 KND92312.1 - 0.055 11.7 0.0 0.08 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2830 PF11125.3 KND92312.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) Acetyltransf_1 PF00583.19 KND92313.1 - 0.00052 19.9 0.1 0.00091 19.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family D123 PF07065.9 KND92314.1 - 5.8e-85 284.9 0.0 1.1e-84 284.0 0.0 1.4 1 1 0 1 1 1 1 D123 AMP-binding PF00501.23 KND92315.1 - 0 2462.7 0.0 1e-86 291.0 0.0 10.5 10 0 0 10 10 10 10 AMP-binding enzyme Condensation PF00668.15 KND92315.1 - 0 1490.2 0.0 1.1e-51 175.5 0.0 12.3 11 1 1 12 12 12 12 Condensation domain PP-binding PF00550.20 KND92315.1 - 6.9e-110 359.3 18.9 4.5e-09 36.4 0.0 11.7 11 0 0 11 11 11 11 Phosphopantetheine attachment site Dak1_2 PF13684.1 KND92315.1 - 5.6 5.7 0.0 90 1.8 0.0 2.9 4 0 0 4 4 4 0 Dihydroxyacetone kinase family Evr1_Alr PF04777.8 KND92316.1 - 1.7e-27 95.1 0.0 3.1e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.21 KND92317.1 - 3.5e-45 153.6 0.1 3.9e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4139 PF13598.1 KND92318.1 - 3.3e-48 164.6 1.1 4e-32 111.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KND92318.1 - 5.2e-10 39.7 5.8 2.4e-09 37.5 0.6 3.8 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) RPAP2_Rtr1 PF04181.8 KND92319.1 - 2.2e-16 59.7 0.0 3.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF3364 PF11844.3 KND92319.1 - 0.01 15.8 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) DUF3543 PF12063.3 KND92323.1 - 6.5e-86 287.4 0.1 1.2e-85 286.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KND92323.1 - 4.4e-54 183.3 0.0 1.4e-52 178.3 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92323.1 - 2.8e-36 124.9 0.0 1.9e-35 122.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND92323.1 - 0.064 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3493 PF11998.3 KND92324.1 - 0.094 12.6 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) AT_hook PF02178.14 KND92325.1 - 0.018 14.6 1.5 0.13 12.0 1.0 2.5 1 0 0 1 1 1 0 AT hook motif Ribosomal_L41 PF05162.8 KND92326.1 - 1.1e-09 37.8 28.0 1.1e-09 37.7 19.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 KND92326.1 - 0.2 11.3 1.5 0.21 11.2 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) RNA_pol_I_A49 PF06870.7 KND92327.1 - 1.4e-75 254.3 0.1 1.6e-75 254.0 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Zeta_toxin PF06414.7 KND92328.1 - 5.2e-42 143.2 0.0 2.6e-41 140.9 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KND92328.1 - 1.6e-07 31.2 1.0 3.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zn_clus PF00172.13 KND92328.1 - 0.00094 19.0 5.1 0.0016 18.2 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 KND92329.1 - 4.7e-25 88.1 0.0 5.5e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Vps51 PF08700.6 KND92330.1 - 1.9e-13 50.0 0.0 6.6e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 MFS_1 PF07690.11 KND92331.1 - 7.8e-43 146.5 28.1 8.4e-40 136.5 13.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KND92331.1 - 0.036 12.1 1.3 1.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF973 PF06157.6 KND92331.1 - 0.31 9.9 7.5 0.014 14.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF2841 PF11001.3 KND92332.1 - 7.6e-39 132.4 3.8 1.2e-38 131.8 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF4109 PF13397.1 KND92332.1 - 0.51 10.7 0.1 0.51 10.7 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4109) HLH PF00010.21 KND92333.1 - 8.2e-13 47.8 0.2 1.7e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rootletin PF15035.1 KND92333.1 - 0.015 15.3 3.1 0.024 14.6 2.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_28 PF13521.1 KND92333.1 - 0.12 12.3 0.3 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 KND92333.1 - 0.22 10.1 3.1 0.4 9.2 2.1 1.3 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 KND92333.1 - 0.27 10.7 1.9 0.74 9.3 1.3 1.8 1 1 0 1 1 1 0 Septum formation initiator DUF2946 PF11162.3 KND92334.1 - 0.086 13.0 5.2 0.18 11.9 3.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) CLTH PF10607.4 KND92335.1 - 1.2e-26 93.1 0.0 3.2e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KND92335.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 LisH NUDIX PF00293.23 KND92336.1 - 6.4e-19 67.9 0.1 1.3e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KND92336.1 - 8.6e-13 48.4 0.0 3.1e-12 46.6 0.0 1.9 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KND92336.1 - 6.1e-09 35.2 0.8 1e-08 34.5 0.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HEAT_2 PF13646.1 KND92337.1 - 0.00096 19.3 6.2 0.43 10.9 0.0 5.3 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.17 KND92337.1 - 0.081 13.0 0.3 17 5.7 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KND92337.1 - 0.092 13.2 1.5 22 5.6 0.0 4.4 3 0 0 3 3 3 0 HEAT-like repeat DUF1749 PF08538.5 KND92338.1 - 2.2e-82 276.3 0.0 2.6e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KND92338.1 - 3e-15 56.7 0.0 3.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92338.1 - 3.8e-08 33.2 0.0 7.3e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND92338.1 - 7e-05 22.4 0.1 0.039 13.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KND92338.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 KND92338.1 - 0.07 12.7 0.0 0.16 11.5 0.0 1.6 1 1 1 2 2 2 0 PGAP1-like protein ABC_membrane PF00664.18 KND92339.1 - 3.6e-83 279.1 32.4 2.6e-45 155.0 6.6 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND92339.1 - 8.2e-48 162.1 0.0 1.7e-30 106.1 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND92339.1 - 1.2e-08 34.5 2.7 0.0004 19.6 0.1 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KND92339.1 - 6.4e-05 22.8 0.1 0.36 10.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KND92339.1 - 9.9e-05 22.4 1.0 0.03 14.3 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KND92339.1 - 0.00027 21.4 0.1 1.4 9.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 KND92339.1 - 0.00027 20.3 0.1 0.21 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND92339.1 - 0.00051 19.5 1.1 0.31 10.6 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 KND92339.1 - 0.00061 19.0 0.1 0.62 9.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 KND92339.1 - 0.0017 18.3 0.2 6.9 6.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 KND92339.1 - 0.0047 16.7 2.0 0.14 11.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 KND92339.1 - 0.011 15.2 0.1 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KND92339.1 - 0.02 15.2 0.1 7.9 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KND92339.1 - 0.033 13.7 2.6 6.5 6.2 0.0 3.4 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 KND92339.1 - 0.051 13.3 3.3 0.54 10.0 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 KND92339.1 - 0.09 12.9 0.0 4.7 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KND92339.1 - 0.12 12.0 1.0 0.63 9.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KND92339.1 - 0.16 11.0 0.1 7.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KND92339.1 - 0.2 11.8 1.3 33 4.6 0.1 3.4 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 KND92339.1 - 0.6 9.1 2.1 4 6.4 0.1 2.4 2 0 0 2 2 2 0 AIG1 family CAF1 PF04857.15 KND92340.1 - 1.8e-64 217.6 0.0 2.3e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 KND92340.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain APH PF01636.18 KND92342.1 - 0.0022 17.7 0.6 0.1 12.3 0.4 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Dsl1_N PF11988.3 KND92342.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal p450 PF00067.17 KND92343.1 - 3.2e-51 174.2 0.0 4.3e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_5 PF13873.1 KND92343.1 - 0.082 12.8 0.1 16 5.4 0.1 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Acetyltransf_7 PF13508.1 KND92344.1 - 1.3e-11 44.4 0.1 9.6e-11 41.6 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND92344.1 - 3.9e-10 39.6 0.0 1.2e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KND92344.1 - 5.9e-08 32.6 0.1 1.5e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND92344.1 - 1.1e-07 32.0 0.2 2.5e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND92344.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KND92344.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KND92344.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RRP7 PF12923.2 KND92344.1 - 0.051 13.6 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Acetyltransf_CG PF14542.1 KND92344.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Bunya_NS-S PF01104.12 KND92346.1 - 0.22 10.9 0.9 0.34 10.4 0.6 1.2 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Cullin PF00888.17 KND92347.1 - 2.8e-117 392.7 0.0 3.3e-116 389.1 0.0 2.7 3 1 0 4 4 4 1 Cullin family PI3_PI4_kinase PF00454.22 KND92347.1 - 6.8e-44 150.0 0.0 1.3e-43 149.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KND92347.1 - 5.5e-40 136.6 0.5 3.6e-38 130.7 0.0 3.3 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair Cullin_Nedd8 PF10557.4 KND92347.1 - 3.6e-18 65.1 2.8 2.7e-16 59.1 0.5 2.9 2 0 0 2 2 2 2 Cullin protein neddylation domain FATC PF02260.15 KND92347.1 - 7.8e-08 31.6 0.1 1.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain Fer2_3 PF13085.1 KND92348.1 - 3.9e-33 113.5 0.0 6e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KND92348.1 - 1.8e-09 37.8 6.5 1.8e-09 37.8 4.5 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KND92348.1 - 2e-09 37.3 4.6 2e-09 37.3 3.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KND92348.1 - 5e-05 23.0 4.3 5e-05 23.0 3.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KND92348.1 - 5.5e-05 23.5 1.9 5.5e-05 23.5 1.3 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KND92348.1 - 5.6e-05 23.3 4.8 0.024 14.8 0.6 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KND92348.1 - 0.0012 18.5 3.0 0.0024 17.5 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KND92348.1 - 0.0084 16.4 5.9 0.0084 16.4 4.1 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KND92348.1 - 0.042 14.2 1.2 0.44 10.9 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KND92348.1 - 8.3 7.0 7.7 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Nup188 PF10487.4 KND92350.1 - 3e-23 81.7 0.8 1.5e-21 76.1 0.2 2.3 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF2642 PF10842.3 KND92350.1 - 0.12 11.8 0.0 17 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) IGPS PF00218.16 KND92351.1 - 4.2e-92 307.7 0.0 6.3e-92 307.2 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KND92351.1 - 2.7e-52 177.0 0.0 3.9e-51 173.2 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 KND92351.1 - 9.2e-49 165.6 0.2 7.5e-45 152.9 0.0 2.9 2 1 0 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 KND92351.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.13 KND92351.1 - 0.032 13.0 0.0 0.078 11.8 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase QRPTase_C PF01729.14 KND92351.1 - 0.035 13.6 0.6 1.2 8.6 0.1 2.7 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain zf-C3HC4_3 PF13920.1 KND92352.1 - 0.0073 15.9 3.0 0.01 15.4 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND92352.1 - 0.024 14.6 4.9 0.042 13.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 KND92352.1 - 0.049 13.1 5.4 0.087 12.3 3.7 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-B_box PF00643.19 KND92352.1 - 0.066 13.1 2.6 0.095 12.6 1.8 1.3 1 0 0 1 1 1 0 B-box zinc finger BRCT PF00533.21 KND92353.1 - 0.036 14.2 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KND92353.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Methyltransf_2 PF00891.13 KND92354.1 - 9.5e-23 80.6 0.0 1e-21 77.2 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase SPOUT_MTase PF02590.12 KND92354.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase CMAS PF02353.15 KND92356.1 - 1e-62 211.7 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KND92356.1 - 2.2e-13 50.2 0.0 2.6e-12 46.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND92356.1 - 3.7e-09 36.9 0.0 7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND92356.1 - 8.6e-05 22.8 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND92356.1 - 0.00046 20.6 0.0 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND92356.1 - 0.0012 19.4 0.1 0.0042 17.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND92356.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND92356.1 - 0.0027 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND92356.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KND92356.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KND92356.1 - 0.089 12.4 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.17 KND92357.1 - 1.9e-13 50.5 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KND92357.1 - 6.5e-05 22.2 0.0 0.00028 20.1 0.0 1.8 2 1 0 3 3 3 1 Sulfatase Metalloenzyme PF01676.13 KND92357.1 - 0.0039 16.6 0.5 0.007 15.7 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MaoC_dehydratas PF01575.14 KND92358.1 - 9.1e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain Abhydrolase_6 PF12697.2 KND92361.1 - 4.7e-07 29.9 0.0 1.6e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KND92361.1 - 5.7e-07 29.6 0.1 2.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KND92361.1 - 1.6e-06 27.8 1.0 1e-05 25.2 0.3 2.7 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KND92361.1 - 2.7e-06 27.5 0.0 4.8e-05 23.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF676 PF05057.9 KND92361.1 - 7.2e-05 22.1 0.0 0.00022 20.6 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND92361.1 - 0.0021 17.7 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein KAP_NTPase PF07693.9 KND92361.1 - 0.0031 16.5 0.1 0.24 10.3 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain Abhydrolase_5 PF12695.2 KND92361.1 - 0.0096 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.24 KND92361.1 - 0.033 14.3 0.1 1.3 9.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KND92361.1 - 0.041 14.0 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 KND92361.1 - 0.048 12.5 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KND92361.1 - 0.057 12.8 0.1 0.22 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KND92361.1 - 0.092 13.5 0.5 0.69 10.7 0.0 2.7 2 1 0 3 3 2 0 AAA domain AAA_30 PF13604.1 KND92361.1 - 0.093 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KND92361.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 KND92361.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Synaptobrevin PF00957.16 KND92362.1 - 1.2e-30 104.9 0.3 1.6e-30 104.5 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KND92362.1 - 1.6e-23 82.0 0.0 2.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 KND92362.1 - 0.035 14.3 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 SpoIIAA-like SUV3_C PF12513.3 KND92363.1 - 5.7e-13 48.0 1.0 1.1e-12 47.1 0.7 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KND92363.1 - 1.9e-07 30.8 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ADC PF06314.6 KND92364.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Cyclin PF08613.6 KND92365.1 - 2.6e-38 131.7 6.3 1.9e-23 83.5 0.1 3.1 3 0 0 3 3 3 2 Cyclin gerPA PF10676.4 KND92365.1 - 0.15 11.9 1.1 0.81 9.5 0.1 2.6 2 1 1 3 3 3 0 Spore germination protein gerPA/gerPF BAF1_ABF1 PF04684.8 KND92365.1 - 2.7 6.7 27.9 0.39 9.5 10.7 3.1 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Beta_elim_lyase PF01212.16 KND92366.1 - 4e-64 216.5 0.0 5.6e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KND92366.1 - 4.2e-07 28.5 0.0 7.6e-07 27.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KND92366.1 - 9.8e-05 21.4 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KND92366.1 - 0.0011 17.7 0.1 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KND92366.1 - 0.0073 15.3 0.1 0.018 14.0 0.1 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Hint_2 PF13403.1 KND92366.1 - 0.092 12.6 0.0 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Hint domain Tyrosinase PF00264.15 KND92367.1 - 1.6e-55 188.7 2.1 1.6e-55 188.7 1.4 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Glyco_transf_17 PF04724.8 KND92371.1 - 2.5e-42 145.1 0.0 3.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 YbjQ_1 PF01906.12 KND92372.1 - 9.9e-24 83.7 0.1 1.2e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding RNA_pol_Rpb2_6 PF00562.23 KND92373.1 - 2.3e-111 372.2 0.1 3.1e-111 371.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KND92373.1 - 7.2e-29 100.1 0.0 1.2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KND92373.1 - 2.2e-25 89.1 0.0 3.8e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KND92373.1 - 1.4e-23 82.4 0.0 6.5e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KND92373.1 - 3.8e-23 81.1 0.1 1.2e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KND92373.1 - 4.4e-16 58.9 0.0 1.8e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KND92373.1 - 0.0051 16.7 0.1 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 KND92373.1 - 0.07 12.9 0.3 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Clathrin PF00637.15 KND92374.1 - 1e-203 667.1 36.4 3.2e-33 114.3 1.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KND92374.1 - 1.6e-30 104.8 1.7 3.1e-30 103.8 0.3 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 KND92374.1 - 2.7e-29 99.3 0.5 4.9e-05 23.3 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_12 PF13424.1 KND92374.1 - 6.1e-06 26.0 4.5 0.45 10.4 0.0 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KND92374.1 - 2.2e-05 23.8 9.3 1.9 8.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 KND92374.1 - 0.0002 20.2 7.4 0.1 11.3 0.1 4.7 5 0 0 5 5 5 2 Coatomer WD associated region TPR_14 PF13428.1 KND92374.1 - 0.00037 20.8 10.2 6.9 7.6 0.0 7.9 9 1 1 10 10 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND92374.1 - 0.0031 17.8 2.5 7.8 6.9 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND92374.1 - 0.021 14.4 5.5 1.6 8.4 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2191 PF09957.4 KND92374.1 - 0.054 13.3 0.3 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_16 PF13432.1 KND92374.1 - 0.071 13.8 2.0 10 6.9 0.0 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND92374.1 - 0.54 10.3 11.4 1.5 8.8 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KND92374.1 - 4.4 7.0 12.0 6.5 6.4 0.1 5.7 6 0 0 6 6 6 0 TPR repeat NifU_N PF01592.11 KND92375.1 - 9.4e-47 158.1 0.1 3.3e-40 136.9 0.0 2.0 1 1 1 2 2 2 2 NifU-like N terminal domain MR_MLE_N PF02746.11 KND92375.1 - 0.055 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DNA_pol_A PF00476.15 KND92376.1 - 4.1e-104 348.2 0.0 5.8e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A Voltage_CLC PF00654.15 KND92377.1 - 5.1e-90 302.0 27.6 5.1e-90 302.0 19.1 1.3 2 0 0 2 2 2 1 Voltage gated chloride channel Neurochondrin PF05536.6 KND92378.1 - 1.7e-102 343.4 0.8 2.4e-102 342.9 0.6 1.2 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 KND92378.1 - 2.2e-06 27.4 0.1 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Imm16 PF15565.1 KND92378.1 - 0.031 14.1 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 16 Sec7_N PF12783.2 KND92378.1 - 0.045 13.1 0.1 0.18 11.2 0.1 2.0 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_N PF03224.9 KND92378.1 - 0.053 12.6 2.4 4.5 6.3 0.1 2.9 3 1 0 3 3 3 0 V-ATPase subunit H ATP-synt_D PF01813.12 KND92379.1 - 0.00012 21.6 0.9 0.00017 21.1 0.1 1.6 2 0 0 2 2 2 1 ATP synthase subunit D DUF904 PF06005.7 KND92379.1 - 0.076 13.3 0.2 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF2880 PF11082.3 KND92379.1 - 0.11 12.4 1.5 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) DUF1943 PF09172.6 KND92380.1 - 1.2 7.9 5.4 2.5 6.8 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Zip PF02535.17 KND92381.1 - 1.4e-36 126.1 17.7 6.5e-28 97.6 6.7 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.27 KND92382.1 - 9.8e-49 161.5 19.6 2e-09 36.9 0.5 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KND92382.1 - 1.8e-12 46.7 0.6 3.9e-12 45.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KND92382.1 - 1.1e-06 27.0 10.5 0.73 7.8 0.0 5.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KND92382.1 - 4.2e-06 26.2 2.0 9.1e-06 25.2 1.4 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 KND92382.1 - 0.12 12.7 3.4 12 6.3 0.0 4.3 3 1 1 4 4 4 0 PQQ-like domain E1_dh PF00676.15 KND92383.1 - 5.1e-111 370.1 0.8 5.1e-111 370.1 0.5 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component DNA_ligase_A_M PF01068.16 KND92383.1 - 9.1e-58 194.9 3.4 6.7e-47 159.4 0.2 3.0 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KND92383.1 - 2.5e-51 173.9 0.0 4.7e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KND92383.1 - 4e-27 94.4 0.0 1.8e-26 92.3 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DXP_synthase_N PF13292.1 KND92383.1 - 0.0076 15.2 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase SPC25 PF06703.6 KND92384.1 - 2.6e-51 173.4 0.0 3.1e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Peripla_BP_4 PF13407.1 KND92384.1 - 0.02 14.2 0.1 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF106 PF01956.11 KND92385.1 - 2e-54 183.6 1.0 2.8e-54 183.1 0.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cytochrom_B_N PF00033.14 KND92385.1 - 0.049 12.9 0.5 0.89 8.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Alg6_Alg8 PF03155.10 KND92386.1 - 4.3e-127 424.8 26.7 5.3e-80 269.5 8.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF2975 PF11188.3 KND92386.1 - 1.8 8.2 14.7 0.93 9.2 4.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) SpoIIE PF07228.7 KND92387.1 - 2.2e-11 43.8 0.3 1.3e-10 41.3 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KND92387.1 - 1.3e-08 34.5 0.1 2.1e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KND92387.1 - 0.00015 21.2 0.0 0.06 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C RNA_pol_Rbc25 PF08292.7 KND92389.1 - 9.9e-35 119.3 0.0 1.4e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KND92389.1 - 3.3e-14 52.7 0.0 4.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.4 KND92390.1 - 7.6e-10 38.1 0.1 2e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) YPEB PF14620.1 KND92390.1 - 0.038 13.0 0.6 0.056 12.4 0.4 1.1 1 0 0 1 1 1 0 YpeB sporulation zf-CCCH PF00642.19 KND92390.1 - 0.11 12.1 6.0 0.27 10.9 4.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) eIF-3c_N PF05470.7 KND92390.1 - 0.32 9.0 5.9 0.43 8.6 4.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SPT2 PF08243.6 KND92391.1 - 3.3e-07 30.6 21.9 4.1e-05 23.8 7.3 2.4 1 1 1 2 2 2 2 SPT2 chromatin protein TFIIA PF03153.8 KND92391.1 - 0.5 10.1 7.9 0.77 9.5 5.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 KND92392.1 - 1.9e-27 95.4 11.1 2.2e-27 95.2 7.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein HTH_28 PF13518.1 KND92393.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain 4HBT_3 PF13622.1 KND92393.1 - 6.8 6.3 9.1 4.3 7.0 5.4 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily Methyltransf_23 PF13489.1 KND92394.1 - 2.1e-09 37.3 0.0 4.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND92394.1 - 2.4e-05 24.7 0.0 8.6e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND92394.1 - 0.00019 21.8 0.0 0.00046 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND92394.1 - 0.0075 16.8 0.0 0.025 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Herpes_capsid PF06112.6 KND92394.1 - 0.01 15.8 2.6 0.01 15.8 1.8 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Methyltransf_31 PF13847.1 KND92394.1 - 0.014 15.0 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_C PF00137.16 KND92395.1 - 2.3e-27 94.6 25.4 1.6e-16 59.9 7.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 KND92395.1 - 0.29 10.6 4.5 5 6.6 0.1 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF4064 PF13273.1 KND92395.1 - 6 7.0 14.8 0.48 10.5 2.8 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3816 PF12822.2 KND92395.1 - 6.1 6.6 13.7 1.6 8.6 6.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Pep3_Vps18 PF05131.9 KND92396.1 - 3.6e-42 143.2 0.0 1.2e-41 141.5 0.0 2.0 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KND92396.1 - 2.2e-11 43.5 7.9 1.6e-07 30.9 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.4 KND92396.1 - 5.9e-05 23.0 1.3 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.1 KND92396.1 - 0.00026 20.7 0.5 0.00026 20.7 0.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KND92396.1 - 0.0015 18.2 0.7 0.0015 18.2 0.5 1.7 2 0 0 2 2 2 1 zinc-RING finger domain DUF1086 PF06461.6 KND92396.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Vps39_2 PF10367.4 KND92396.1 - 0.048 13.8 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 KND92396.1 - 0.056 13.4 0.6 0.15 12.1 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND92396.1 - 0.11 12.1 0.4 0.33 10.6 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mit_ribos_Mrp51 PF11709.3 KND92396.1 - 0.15 11.2 0.3 0.29 10.3 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Abhydrolase_6 PF12697.2 KND92397.1 - 3.2e-08 33.7 0.1 4.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND92397.1 - 8.2e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KND92397.1 - 3.6e-05 23.5 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KND92397.1 - 0.00012 21.4 0.0 0.00055 19.2 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_9 PF10081.4 KND92397.1 - 0.049 12.3 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_8 PF06259.7 KND92397.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Asp PF00026.18 KND92398.1 - 1.4e-68 231.5 2.2 1.6e-68 231.2 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND92398.1 - 9.1e-10 38.7 1.4 1.6e-09 37.8 0.4 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KND92398.1 - 2.3e-05 24.0 0.0 7.6e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KND92398.1 - 0.00047 20.5 1.2 0.73 10.3 0.1 3.9 3 1 0 3 3 3 2 Aspartyl protease Homeobox_KN PF05920.6 KND92399.1 - 5.4e-20 70.8 0.4 1.6e-19 69.3 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KND92399.1 - 2.6e-08 33.3 1.3 6.1e-08 32.1 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain ABC_tran PF00005.22 KND92400.1 - 5.1e-05 23.6 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Epimerase PF01370.16 KND92401.1 - 1.1e-57 195.1 0.1 1.4e-57 194.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND92401.1 - 1.5e-22 79.6 0.0 2.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND92401.1 - 8e-22 77.3 0.0 2.9e-21 75.5 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KND92401.1 - 1.1e-21 76.9 0.0 1e-20 73.8 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KND92401.1 - 1.5e-21 76.6 0.0 2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KND92401.1 - 7e-09 35.9 0.0 1.5e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KND92401.1 - 0.0042 17.0 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KND92401.1 - 0.087 12.0 0.2 0.5 9.5 0.1 2.0 1 1 0 1 1 1 0 NmrA-like family Methyltransf_33 PF10017.4 KND92402.1 - 7.2e-28 97.0 0.0 1.2e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KND92402.1 - 9.8e-14 51.3 0.7 5.8e-13 48.8 0.5 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KND92402.1 - 4.7e-06 26.9 3.4 1.1e-05 25.8 0.2 2.7 3 0 0 3 3 3 1 DinB superfamily Methyltransf_25 PF13649.1 KND92402.1 - 0.029 14.7 0.1 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain IF-2B PF01008.12 KND92403.1 - 3.9e-46 157.2 0.0 4.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4224 PF13986.1 KND92403.1 - 0.074 12.6 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Peptidase_C2 PF00648.16 KND92404.1 - 0.001 18.1 0.2 0.001 18.1 0.1 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease DUF2102 PF09875.4 KND92404.1 - 0.45 10.0 4.2 0.89 9.1 2.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) GalP_UDP_transf PF01087.17 KND92405.1 - 3e-65 219.6 0.0 4.2e-63 212.6 0.0 2.1 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KND92405.1 - 8.3e-53 178.3 0.0 1.7e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KND92405.1 - 0.0097 16.4 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 HIT domain Erg28 PF03694.8 KND92406.1 - 1e-44 151.0 0.1 1.3e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF1625 PF07787.7 KND92406.1 - 0.84 8.8 4.6 1.2 8.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) adh_short PF00106.20 KND92407.1 - 1.4e-22 80.3 0.0 2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND92407.1 - 8.7e-13 48.5 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND92407.1 - 4.4e-06 26.4 0.0 8.1e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND92407.1 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KND92407.1 - 0.036 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KND92407.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA-synt_His PF13393.1 KND92408.1 - 2.5e-39 135.1 0.0 3.8e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KND92408.1 - 9.3e-17 61.1 0.0 1.8e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND92408.1 - 3.9e-08 33.1 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KND92408.1 - 9.9e-05 21.2 0.0 0.002 16.9 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KND92408.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Nucleoporin_C PF03177.9 KND92409.1 - 2.3e-122 409.4 2.4 3.3e-107 359.4 0.4 2.1 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KND92409.1 - 2.2e-83 280.3 0.1 3.4e-83 279.7 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like VWA_2 PF13519.1 KND92409.1 - 0.011 15.9 0.2 0.59 10.2 0.0 3.2 1 1 1 2 2 2 0 von Willebrand factor type A domain SRI PF08236.6 KND92409.1 - 0.31 11.0 0.3 7.2 6.6 0.0 2.4 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF2781 PF10914.3 KND92411.1 - 9.5e-21 74.1 6.0 1.1e-20 73.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) AMP-binding PF00501.23 KND92412.1 - 4.1e-82 275.7 0.0 5.1e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND92412.1 - 1.1e-12 48.6 0.8 4.8e-12 46.6 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KND92413.1 - 3.8e-35 121.2 33.6 3.8e-35 121.2 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND92413.1 - 6.2e-18 64.6 3.6 6.2e-18 64.6 2.5 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KND92413.1 - 6.6e-09 34.5 1.3 1.1e-08 33.8 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PrpF PF04303.8 KND92414.1 - 3.1e-84 282.8 0.2 3.5e-84 282.6 0.1 1.0 1 0 0 1 1 1 1 PrpF protein AIG2_2 PF13772.1 KND92416.1 - 1.9e-05 24.6 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KND92416.1 - 0.00012 22.5 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Pkinase PF00069.20 KND92417.1 - 3.6e-67 226.2 0.0 6.8e-67 225.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92417.1 - 7.6e-49 166.1 0.0 1.3e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KND92417.1 - 1.1e-28 99.1 0.0 1.9e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KND92417.1 - 6.3e-15 54.7 0.3 4.2e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KND92417.1 - 3.4e-14 52.7 0.1 6.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KND92417.1 - 8.5e-13 48.6 0.1 1.6e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KND92417.1 - 1.5e-06 27.3 0.0 0.00046 19.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KND92417.1 - 0.053 12.5 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_PNT PF02198.11 KND92417.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 KND92417.1 - 0.23 11.5 1.5 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Relaxase PF03432.9 KND92417.1 - 0.36 10.1 1.8 0.37 10.1 0.0 1.9 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain PDT PF00800.13 KND92418.1 - 7.2e-65 217.9 0.0 8.8e-65 217.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KND92418.1 - 9.6e-06 24.9 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 KND92418.1 - 0.011 16.0 0.0 8.4 6.8 0.0 2.4 2 0 0 2 2 2 0 ACT domain Dynamin_N PF00350.18 KND92419.1 - 1e-24 87.2 0.0 2.9e-24 85.7 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND92419.1 - 9.1e-06 24.6 0.0 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 KND92419.1 - 0.00023 20.9 0.0 0.00083 19.2 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain COG5 PF10392.4 KND92419.1 - 0.023 14.6 1.6 0.08 12.8 0.2 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FeoB_N PF02421.13 KND92419.1 - 0.04 13.2 0.0 0.34 10.1 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B 2OG-FeII_Oxy PF03171.15 KND92420.1 - 4.3e-16 59.0 0.0 7.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KND92420.1 - 5.5e-05 23.6 0.0 0.0001 22.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Condensation PF00668.15 KND92421.1 - 3.9e-17 62.0 0.0 7.4e-17 61.1 0.0 1.5 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KND92421.1 - 3.4e-12 46.4 0.0 8e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1515 PF07439.6 KND92422.1 - 0.044 13.6 0.9 0.056 13.2 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Polysacc_deac_1 PF01522.16 KND92423.1 - 1.8e-32 111.5 0.0 2.5e-31 107.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KND92423.1 - 0.0029 17.5 14.3 0.0051 16.7 9.9 1.3 1 0 0 1 1 1 1 Chitin recognition protein Macoilin PF09726.4 KND92424.1 - 2.1 6.5 7.6 2.3 6.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein TauD PF02668.11 KND92425.1 - 9.6e-56 189.3 0.4 1.1e-55 189.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KND92426.1 - 4.5e-10 38.7 55.7 1.1e-08 34.2 37.4 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily BTB PF00651.26 KND92427.1 - 4.2e-09 36.3 0.1 1.2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain OprB PF04966.7 KND92428.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family ig PF00047.20 KND92428.1 - 0.2 11.8 0.8 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Auxin_repressed PF05564.7 KND92429.1 - 0.024 15.2 0.5 0.033 14.7 0.4 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein ADH_zinc_N PF00107.21 KND92431.1 - 2.1e-29 101.7 0.3 9.6e-29 99.5 0.2 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND92431.1 - 1e-10 41.3 0.0 6.5e-10 38.7 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KND92432.1 - 5e-44 150.5 0.0 7.6e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KND92432.1 - 8.8e-24 83.2 0.1 1.7e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KND92432.1 - 3.9e-15 55.2 0.0 2e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KND92432.1 - 3.5e-14 52.3 0.0 2.7e-12 46.2 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KND92432.1 - 1.5e-12 47.0 0.0 2.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KND92432.1 - 1.7e-12 47.5 0.1 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND92432.1 - 1.1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND92432.1 - 1.2e-09 38.4 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND92432.1 - 1.8e-08 33.6 0.0 6.4e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KND92432.1 - 0.00091 18.5 0.1 0.0051 16.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 KND92432.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND92432.1 - 0.06 12.7 0.3 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3533 PF12051.3 KND92433.1 - 3.2e-94 315.8 13.1 3.8e-94 315.5 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ank_2 PF12796.2 KND92435.1 - 2.8e-24 85.2 1.0 4e-15 55.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND92435.1 - 1.1e-20 73.5 0.2 3.7e-07 30.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND92435.1 - 4.9e-20 71.1 2.0 3.9e-08 33.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KND92435.1 - 1.5e-19 68.6 3.9 3.3e-05 23.4 0.0 4.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 KND92435.1 - 7.7e-17 59.7 0.1 2.9e-05 23.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF3881 PF12997.2 KND92435.1 - 0.061 12.3 0.0 0.13 11.2 0.0 1.4 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF2235 PF09994.4 KND92438.1 - 2.5e-104 348.5 0.3 2.5e-104 348.5 0.2 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) adh_short PF00106.20 KND92438.1 - 1.8e-12 47.5 0.3 5e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND92438.1 - 7.2e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND92438.1 - 0.0015 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KND92438.1 - 0.0076 16.0 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.2 KND92439.1 - 0.00017 21.2 0.3 0.00083 19.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like APH PF01636.18 KND92440.1 - 1.6e-08 34.6 0.0 6.4e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family TRAM_LAG1_CLN8 PF03798.11 KND92441.1 - 2.8e-34 118.3 16.9 2.8e-34 118.3 11.7 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KND92441.1 - 1.2e-20 72.7 0.0 2.8e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Apt1 PF10351.4 KND92441.1 - 5.8 5.6 5.0 2.4 6.8 1.9 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3494 PF11999.3 KND92442.1 - 3.5e-54 183.5 18.5 4.8e-54 183.1 12.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) ABC_tran PF00005.22 KND92443.1 - 8.5e-33 113.5 0.0 2e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KND92443.1 - 8.4e-20 71.3 1.8 8.4e-20 71.3 1.3 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KND92443.1 - 4e-05 22.9 0.0 0.00018 20.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KND92443.1 - 0.0036 17.1 0.2 0.092 12.6 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KND92443.1 - 0.0058 15.8 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KND92443.1 - 0.024 14.1 0.1 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KND92443.1 - 0.024 14.7 0.1 0.094 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KND92443.1 - 0.025 14.5 0.0 2.7 7.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain muHD PF10291.4 KND92444.1 - 1.8e-64 217.3 0.0 2.9e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KND92444.1 - 2.8e-10 40.2 0.9 9.7e-10 38.5 0.0 2.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain GCOM2 PF15328.1 KND92444.1 - 0.051 13.3 11.2 0.17 11.5 7.8 1.7 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Vps5 PF09325.5 KND92444.1 - 0.06 12.5 7.7 0.14 11.4 5.3 1.6 1 1 0 1 1 1 0 Vps5 C terminal like V_ATPase_I PF01496.14 KND92444.1 - 2.8 5.6 6.0 4.1 5.1 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 KND92445.1 - 1.8e-30 105.9 0.0 2.3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KND92445.1 - 5.7e-06 26.2 0.3 5.9e-05 22.9 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KND92445.1 - 6.6e-05 22.1 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.1 KND92447.1 - 2.2e-09 36.9 7.8 6.7e-09 35.4 5.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KND92447.1 - 8.5e-08 32.1 1.4 2.2e-07 30.8 0.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KND92447.1 - 1.1e-05 25.2 8.4 3.4e-05 23.7 5.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 KND92447.1 - 0.00051 19.6 9.6 0.0011 18.5 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND92447.1 - 0.00096 18.9 2.6 0.00096 18.9 1.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KND92447.1 - 0.0012 18.7 7.9 0.0028 17.6 5.5 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 KND92447.1 - 0.0015 18.2 2.5 0.0015 18.2 1.7 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 KND92447.1 - 0.0027 17.3 5.3 0.0053 16.3 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND92447.1 - 0.0044 17.0 8.8 0.0044 17.0 6.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND92447.1 - 0.098 12.4 8.6 0.2 11.3 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_RING PF05883.6 KND92447.1 - 0.12 12.2 1.5 0.25 11.1 1.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 KND92447.1 - 0.13 12.3 7.6 0.25 11.3 5.3 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 KND92447.1 - 4.1 7.1 6.8 8.5 6.1 4.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KND92447.1 - 5.4 6.6 7.6 1.1e+02 2.5 5.3 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Plectin PF00681.15 KND92448.1 - 0.17 11.4 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 Plectin repeat Palm_thioest PF02089.10 KND92449.1 - 7.2e-53 179.3 0.0 8.9e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 KND92449.1 - 0.00012 21.4 0.0 0.00085 18.6 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.6 KND92449.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.16 KND92450.1 - 6.8e-62 208.6 0.2 6.8e-62 208.6 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family AMP-binding PF00501.23 KND92453.1 - 0 3994.0 0.0 1.8e-84 283.5 0.0 16.3 16 0 0 16 16 16 16 AMP-binding enzyme Condensation PF00668.15 KND92453.1 - 0 2139.0 0.0 5.5e-43 146.9 0.0 16.6 16 0 0 16 16 16 16 Condensation domain PP-binding PF00550.20 KND92453.1 - 2e-166 540.4 61.9 3.3e-11 43.2 0.1 16.9 16 0 0 16 16 16 16 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KND92453.1 - 2e-51 172.8 0.0 0.049 14.5 0.0 17.1 16 0 0 16 16 16 12 AMP-binding enzyme C-terminal domain AATase PF07247.7 KND92453.1 - 5.9e-05 21.8 0.8 4.5 5.6 0.0 6.4 8 0 0 8 8 8 1 Alcohol acetyltransferase Mig-14 PF07395.6 KND92453.1 - 0.0014 17.6 0.0 40 3.0 0.0 5.7 7 0 0 7 7 7 0 Mig-14 ATP12 PF07542.6 KND92453.1 - 0.0097 15.8 8.0 37 4.3 0.0 8.1 10 0 0 10 10 9 0 ATP12 chaperone protein DUF1707 PF08044.6 KND92453.1 - 0.16 11.7 18.8 10 5.9 0.1 6.4 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) Csm1 PF12539.3 KND92453.1 - 0.23 11.9 7.7 86 3.7 0.0 7.5 8 0 0 8 8 7 0 Chromosome segregation protein Csm1/Pcs1 Pescadillo_N PF06732.6 KND92453.1 - 0.79 8.9 0.3 1.9 7.6 0.2 1.5 1 0 0 1 1 1 0 Pescadillo N-terminus GH3 PF03321.8 KND92453.1 - 0.79 8.1 0.2 20 3.5 0.0 3.7 4 0 0 4 4 4 0 GH3 auxin-responsive promoter DUF1820 PF08850.6 KND92453.1 - 1.3 9.1 0.2 2.4e+02 1.9 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1820) HBS1_N PF08938.5 KND92453.1 - 4.6 7.4 1.2 5e+02 0.9 0.0 4.6 4 0 0 4 4 3 0 HBS1 N-terminus ArsC PF03960.10 KND92453.1 - 6 6.9 1.2 5.4e+02 0.7 0.0 4.1 5 0 0 5 5 4 0 ArsC family GSH-S_ATP PF02955.11 KND92453.1 - 6.1 5.9 0.0 19 4.3 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain NSP10 PF09401.5 KND92453.1 - 7.8 6.2 4.1 97 2.7 0.0 3.8 4 0 0 4 4 4 0 RNA synthesis protein NSP10 HbrB PF08539.6 KND92454.1 - 5.6e-54 182.2 0.0 8e-54 181.7 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Vps39_1 PF10366.4 KND92455.1 - 3.7e-35 120.1 0.1 5.2e-34 116.5 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KND92455.1 - 2.7e-27 95.0 0.0 1.1e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KND92455.1 - 8.4e-15 54.9 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 KND92455.1 - 0.00072 19.1 3.0 0.75 9.3 0.1 3.6 3 1 0 3 3 3 2 Region in Clathrin and VPS TPR_1 PF00515.23 KND92455.1 - 0.0058 16.1 1.2 6.9 6.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KND92455.1 - 0.0064 16.6 1.1 0.34 11.0 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KND92455.1 - 0.017 15.4 0.4 1 9.7 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat CLTH PF10607.4 KND92455.1 - 0.12 12.0 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain TPR_11 PF13414.1 KND92455.1 - 0.15 11.7 1.2 1.1e+02 2.4 0.0 4.0 3 1 1 4 4 4 0 TPR repeat TPR_16 PF13432.1 KND92455.1 - 0.17 12.6 0.0 6.2 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat KH_1 PF00013.24 KND92456.1 - 4.6e-42 141.4 9.9 3.2e-15 55.5 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KND92456.1 - 8.2e-31 105.1 16.2 1.1e-10 40.9 1.2 3.8 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KND92456.1 - 1.9e-12 46.5 3.0 0.01 15.3 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KND92456.1 - 5.4e-08 32.3 4.8 0.16 11.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KND92456.1 - 6.5e-05 22.6 4.3 0.041 13.6 0.0 3.6 3 1 1 4 4 4 2 NusA-like KH domain zf-3CxxC PF13695.1 KND92457.1 - 0.013 15.7 0.3 0.016 15.4 0.2 1.2 1 0 0 1 1 1 0 Zinc-binding domain Prothymosin PF03247.9 KND92457.1 - 0.022 14.9 2.2 0.025 14.7 1.6 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family GCC2_GCC3 PF07699.8 KND92457.1 - 0.7 9.5 3.7 3.6 7.2 0.1 2.3 1 1 0 2 2 2 0 GCC2 and GCC3 MLTD_N PF06474.7 KND92458.1 - 0.14 12.3 0.8 1.2 9.3 0.0 2.3 1 1 1 2 2 2 0 MltD lipid attachment motif 6PF2K PF01591.13 KND92460.1 - 1.4e-77 259.7 0.0 2e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KND92460.1 - 1e-31 110.1 0.0 2.2e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KND92460.1 - 1.4e-09 37.9 0.1 2.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND92460.1 - 0.00053 19.2 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 KND92460.1 - 0.0012 18.4 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 KND92460.1 - 0.0027 18.5 0.2 0.14 12.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain LIM_bind PF01803.11 KND92461.1 - 2.1e-73 246.3 0.0 2.1e-73 246.3 0.0 4.5 2 1 1 4 4 4 1 LIM-domain binding protein Asp PF00026.18 KND92463.1 - 3.1e-36 125.2 0.0 4.3e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KND92463.1 - 2.5e-05 23.8 0.0 0.0011 18.5 0.0 2.7 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KND92463.1 - 0.00035 21.0 0.1 1.7 9.1 0.0 2.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KND92463.1 - 0.0048 16.6 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease XPG_I PF00867.13 KND92466.1 - 1.1e-25 89.4 0.0 2.2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KND92466.1 - 1.7e-07 31.4 0.0 4.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain VHS PF00790.14 KND92467.1 - 1.7e-05 24.5 0.0 6.2e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.8 KND92467.1 - 0.0016 18.6 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.1 KND92467.1 - 0.1 12.9 4.3 13 6.3 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3906 PF13046.1 KND92467.1 - 0.18 11.4 0.2 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) zf-C2HC_2 PF13913.1 KND92467.1 - 0.19 11.4 4.7 3.5 7.4 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Actin PF00022.14 KND92468.1 - 1.5e-23 82.8 0.0 3.4e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 Actin zf-C2H2_4 PF13894.1 KND92469.1 - 0.11 12.9 2.5 6.6 7.3 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 KND92470.1 - 2.2e-16 60.2 4.1 3.3e-16 59.6 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND92470.1 - 1.4e-07 31.3 0.8 2.1e-07 30.7 0.6 1.3 1 0 0 1 1 1 1 KR domain Oxidored_FMN PF00724.15 KND92471.1 - 3.8e-53 180.6 0.0 5.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KND92471.1 - 0.00013 20.9 0.2 0.00013 20.9 0.1 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KND92471.1 - 0.022 14.0 0.1 0.067 12.4 0.0 1.8 2 1 0 2 2 2 0 Histidine biosynthesis protein CFEM PF05730.6 KND92472.1 - 0.026 14.3 3.5 0.047 13.5 2.4 1.4 1 0 0 1 1 1 0 CFEM domain UPF0261 PF06792.6 KND92473.1 - 9.3e-10 37.5 0.0 9.9e-10 37.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Epimerase PF01370.16 KND92473.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cellulase PF00150.13 KND92474.1 - 3.7e-42 144.4 0.0 5.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribul_P_3_epim PF00834.14 KND92474.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family F-box-like PF12937.2 KND92475.1 - 3.3e-07 29.9 0.2 6e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND92475.1 - 2.6e-06 26.9 0.1 4.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KND92475.1 - 0.17 11.7 2.0 14 5.7 0.3 3.9 2 2 1 3 3 3 0 WD domain, G-beta repeat PBP1_TM PF14812.1 KND92475.1 - 0.53 10.6 6.8 2.5 8.4 2.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 KND92475.1 - 6.3 7.0 9.3 0.63 10.2 3.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SWIRM PF04433.12 KND92476.1 - 1.7e-15 56.8 0.0 1.1e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain TIM-br_sig_trns PF09370.5 KND92477.1 - 4.1e-136 452.3 0.2 4.6e-136 452.1 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KND92477.1 - 0.00019 20.6 0.1 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase UPF0261 PF06792.6 KND92478.1 - 1.2e-120 402.7 4.1 1.3e-120 402.5 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Fungal_trans PF04082.13 KND92480.1 - 3.3e-19 68.7 0.3 2.9e-18 65.6 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND92480.1 - 0.0019 18.0 4.3 0.006 16.4 2.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnl2_NKP2 PF09447.5 KND92480.1 - 0.04 13.6 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Exonuc_VII_S PF02609.11 KND92480.1 - 0.96 9.2 3.7 4.4 7.1 0.2 3.7 4 0 0 4 4 4 0 Exonuclease VII small subunit zf-C2H2_jaz PF12171.3 KND92481.1 - 2.8e-05 24.0 0.2 5.6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND92481.1 - 0.0026 17.9 0.6 0.0046 17.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Roughex PF06020.6 KND92481.1 - 0.0037 16.0 0.2 0.0043 15.7 0.2 1.1 1 0 0 1 1 1 1 Drosophila roughex protein zf-C2H2_4 PF13894.1 KND92481.1 - 0.0049 17.1 0.2 0.011 16.0 0.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KND92481.1 - 0.05 13.7 0.2 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KND92481.1 - 0.078 13.3 1.1 0.16 12.3 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type NR_Repeat PF14046.1 KND92481.1 - 0.28 10.9 1.8 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Nuclear receptor repeat DUF1691 PF07950.6 KND92482.1 - 5.3e-38 129.3 6.0 1.1e-23 83.2 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Herpes_US9 PF06072.6 KND92482.1 - 0.032 14.0 1.0 0.095 12.5 0.7 1.8 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 PepSY_TM_2 PF13703.1 KND92482.1 - 2.9 8.1 10.2 30 4.8 1.3 3.3 3 0 0 3 3 3 0 PepSY-associated TM helix Glyco_transf_34 PF05637.7 KND92484.1 - 3.2e-69 233.0 0.0 3.9e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KND92484.1 - 0.00018 20.8 0.1 0.013 14.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.14 KND92485.1 - 6e-20 71.0 0.0 8.7e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KND92485.1 - 7.5e-05 21.6 0.0 0.00015 20.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Proteasome PF00227.21 KND92488.1 - 6.8e-55 185.3 0.1 1.7e-32 112.2 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KND92488.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.2 KND92489.1 - 3.6e-10 39.7 3.2 7.7e-09 35.4 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KND92489.1 - 0.00055 19.6 3.9 0.0021 17.8 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 KND92489.1 - 0.52 10.0 7.1 0.067 12.8 1.9 1.8 2 0 0 2 2 2 0 PHD-finger DUF202 PF02656.10 KND92489.1 - 2.9 8.1 5.5 36 4.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GRAB PF10375.4 KND92490.1 - 5.4e-07 28.9 0.2 1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Tup_N PF08581.5 KND92490.1 - 0.00041 20.4 2.3 0.00041 20.4 1.6 4.7 2 1 1 4 4 4 2 Tup N-terminal Reo_sigmaC PF04582.7 KND92490.1 - 0.0091 15.2 15.1 0.01 15.0 1.0 3.1 1 1 1 3 3 3 2 Reovirus sigma C capsid protein Filament PF00038.16 KND92490.1 - 0.032 13.6 54.3 0.036 13.5 20.0 2.6 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.7 KND92490.1 - 0.32 11.2 17.6 2.6 8.3 0.6 4.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 KND92490.1 - 0.42 9.9 25.2 1.1 8.6 1.6 4.0 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 KND92490.1 - 1.1 9.0 64.0 0.39 10.5 8.2 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 KND92490.1 - 3.4 7.6 55.5 1.1 9.2 14.1 3.8 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.7 KND92490.1 - 3.7 7.2 33.9 0.82 9.4 2.6 4.3 1 1 2 4 4 4 0 Laminin Domain II FAD_binding_3 PF01494.14 KND92491.1 - 5.4e-15 55.3 1.1 1.3e-13 50.7 0.8 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KND92491.1 - 0.0081 16.1 0.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND92491.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding RRM_1 PF00076.17 KND92492.1 - 2.1e-14 52.9 0.0 4.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND92492.1 - 1.2e-10 41.1 0.0 2.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND92492.1 - 4.8e-09 35.9 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND92492.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ArdA PF07275.6 KND92493.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein (ArdA) FUSC_2 PF13515.1 KND92493.1 - 0.23 11.3 2.5 0.29 11.0 0.3 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Cu_bind_like PF02298.12 KND92494.1 - 0.0018 18.0 0.1 0.0083 15.9 0.1 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain SMN PF06003.7 KND92495.1 - 7e-06 25.3 6.0 9.9e-05 21.5 0.2 2.4 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) APH PF01636.18 KND92496.1 - 7.5e-05 22.5 0.4 0.0001 22.1 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND92496.1 - 0.0034 17.0 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KND92496.1 - 0.009 15.0 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MYND PF01753.13 KND92497.1 - 4.1e-11 42.5 13.6 4.1e-11 42.5 9.4 1.8 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.1 KND92497.1 - 0.00094 18.9 9.2 0.065 13.1 5.8 2.7 3 0 0 3 3 3 2 Zinc-finger of mitochondrial splicing suppressor 51 Macro_2 PF14519.1 KND92498.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.4 1 1 0 1 1 1 1 Macro-like domain Glyco_hydro_16 PF00722.16 KND92500.1 - 3.1e-12 46.1 0.2 4.1e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KND92500.1 - 1.5e-06 26.7 0.1 0.0045 15.2 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) HsbA PF12296.3 KND92501.1 - 2e-16 59.9 6.0 3.8e-16 59.0 4.1 1.5 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FAD_binding_3 PF01494.14 KND92502.1 - 2.6e-18 66.1 0.0 3.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND92502.1 - 4.9e-08 32.2 0.0 0.00021 20.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND92502.1 - 9e-05 22.8 0.1 0.0018 18.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND92502.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND92502.1 - 0.012 15.4 0.1 0.034 14.0 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND92502.1 - 0.022 13.3 0.1 0.86 8.1 0.0 2.4 2 1 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KND92502.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HrpE PF06188.7 KND92502.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Pyr_redox_3 PF13738.1 KND92502.1 - 0.16 12.0 0.1 1.5 8.8 0.1 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_88 PF07470.8 KND92504.1 - 4e-24 85.2 0.0 5.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Transket_pyr PF02779.19 KND92505.1 - 1.8e-44 151.3 0.0 7.3e-44 149.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KND92505.1 - 5.8e-36 123.1 0.0 1.5e-35 121.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DSHCT PF08148.7 KND92506.1 - 9.2e-59 197.6 0.5 1.8e-58 196.7 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KND92506.1 - 6.6e-20 71.2 0.0 1.8e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND92506.1 - 5.6e-06 26.1 1.9 7e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KND92506.1 - 5.8e-06 25.6 0.7 2.7e-05 23.4 0.5 2.0 1 1 0 1 1 1 1 rRNA-processing arch domain Cut8_C PF08559.5 KND92506.1 - 0.0092 15.8 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Cut8 six-helix bundle ResIII PF04851.10 KND92506.1 - 0.014 15.2 0.0 0.38 10.5 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SPX PF03105.14 KND92509.1 - 6.1e-44 150.8 0.0 1.4e-43 149.7 0.0 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KND92509.1 - 6e-34 117.7 36.5 8.1e-34 117.3 25.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KND92509.1 - 7.3e-11 41.2 29.2 7.3e-11 41.2 20.2 3.0 1 1 2 3 3 3 2 Citrate transporter Nairovirus_M PF07948.6 KND92509.1 - 0.16 10.0 1.2 0.18 9.8 0.1 1.6 2 0 0 2 2 2 0 Nairovirus M polyprotein-like ABC_membrane PF00664.18 KND92510.1 - 4.1e-72 242.8 23.4 1.2e-41 142.9 3.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND92510.1 - 9.4e-63 210.5 0.0 2.9e-30 105.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND92510.1 - 8.6e-15 54.5 0.1 0.00011 21.5 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND92510.1 - 6.1e-10 39.5 0.0 0.3 11.0 0.0 4.1 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 KND92510.1 - 2.7e-08 33.1 1.8 0.0026 17.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KND92510.1 - 2.5e-07 31.5 0.0 0.03 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND92510.1 - 2.2e-05 23.9 0.1 0.83 9.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KND92510.1 - 2.4e-05 24.4 0.2 2.5 8.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 KND92510.1 - 3.3e-05 23.0 0.0 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.24 KND92510.1 - 6.6e-05 23.1 0.1 0.15 12.2 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KND92510.1 - 0.00011 21.4 0.1 0.16 11.1 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KND92510.1 - 0.00018 21.1 4.8 0.25 10.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 KND92510.1 - 0.00033 19.3 0.3 0.0025 16.4 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 KND92510.1 - 0.00033 20.5 0.5 0.21 11.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KND92510.1 - 0.00058 19.9 3.6 0.98 9.3 0.7 3.4 3 1 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.1 KND92510.1 - 0.0006 19.6 0.3 0.93 9.4 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 KND92510.1 - 0.001 18.7 0.2 0.14 11.7 0.1 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.1 KND92510.1 - 0.008 16.4 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND92510.1 - 0.014 15.0 0.2 7.1 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KND92510.1 - 0.039 13.3 4.8 4.2 6.7 0.2 3.5 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 KND92510.1 - 0.041 14.1 0.6 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KND92510.1 - 0.094 12.5 1.9 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_14 PF13173.1 KND92510.1 - 0.15 11.9 0.0 38 4.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 KND92510.1 - 0.25 9.9 0.0 8.8 4.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KND92510.1 - 0.38 10.7 1.5 14 5.6 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase AMP-binding PF00501.23 KND92513.1 - 7.4e-92 307.9 0.0 1.1e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND92513.1 - 3.4e-13 50.3 0.0 1.6e-12 48.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 KND92513.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pyr_redox PF00070.22 KND92514.1 - 4.8e-15 55.7 2.4 3.6e-13 49.7 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND92514.1 - 2.2e-09 37.6 0.3 0.00014 21.9 0.1 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND92514.1 - 6.5e-09 35.9 0.0 0.00029 20.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND92514.1 - 5.8e-07 28.7 0.1 1.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KND92514.1 - 0.00026 20.0 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KND92514.1 - 0.00047 19.3 1.9 0.016 14.3 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KND92514.1 - 0.0042 16.0 0.5 0.012 14.5 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND92514.1 - 0.018 13.5 1.8 0.23 9.8 0.2 2.2 1 1 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 KND92514.1 - 0.061 13.5 0.4 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 KND92514.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 KND92514.1 - 0.68 8.4 3.3 0.26 9.8 0.2 1.8 3 0 0 3 3 3 0 Tryptophan halogenase MFS_1 PF07690.11 KND92515.1 - 4.3e-22 78.3 50.0 1.4e-13 50.3 15.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KND92515.1 - 3e-06 25.7 24.0 4.6e-06 25.1 16.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KND92516.1 - 2.4e-84 283.5 25.0 2.9e-84 283.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND92516.1 - 8.7e-18 64.1 35.0 2.6e-17 62.5 15.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KND92518.1 - 0.0013 18.9 18.3 0.17 12.2 0.7 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KND92518.1 - 0.063 13.4 3.4 0.67 10.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KND92518.1 - 0.072 13.4 2.2 0.072 13.4 1.5 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KND92518.1 - 0.18 11.9 7.7 4.9 7.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND92518.1 - 0.26 11.2 3.3 16 5.5 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger APH PF01636.18 KND92519.1 - 4.1e-07 29.9 0.2 6.1e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Xan_ur_permease PF00860.15 KND92521.1 - 3.5e-25 88.3 37.4 4.3e-24 84.7 23.6 2.7 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.15 KND92521.1 - 1e-05 24.7 7.2 0.00057 18.9 3.7 2.6 1 1 1 2 2 2 2 Sulfate transporter family Alpha-amylase PF00128.19 KND92524.1 - 5.6e-94 315.0 0.0 7.3e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KND92524.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme VEFS-Box PF09733.4 KND92526.1 - 6.2e-05 22.6 0.1 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF382 PF04037.8 KND92527.1 - 1.1e-60 203.1 0.3 1.1e-60 203.1 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 KND92527.1 - 8.4e-19 66.6 4.8 1.9e-18 65.5 3.3 1.7 1 0 0 1 1 1 1 PSP BSP_II PF05432.6 KND92527.1 - 0.0084 15.4 13.8 0.0084 15.4 9.6 2.4 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) TPT PF03151.11 KND92528.1 - 6.6e-40 136.2 3.7 6.6e-40 136.2 2.6 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KND92528.1 - 1.4e-09 37.2 11.0 7.2e-09 34.9 7.6 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KND92528.1 - 6.8e-07 29.3 31.8 0.00043 20.3 8.0 3.2 3 1 0 3 3 3 2 EamA-like transporter family Multi_Drug_Res PF00893.14 KND92528.1 - 1.8 9.1 9.5 0.53 10.7 1.2 3.0 3 0 0 3 3 3 0 Small Multidrug Resistance protein Mus7 PF09462.5 KND92529.1 - 3e-132 442.5 0.9 6e-132 441.5 0.6 1.5 1 0 0 1 1 1 1 Mus7/MMS22 family ORC5_C PF14630.1 KND92529.1 - 1e-77 261.2 0.0 2e-77 260.3 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Zn_clus PF00172.13 KND92531.1 - 6.7e-07 29.1 6.2 1.5e-06 28.0 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_AsnC-type PF13404.1 KND92531.1 - 0.019 14.5 0.5 0.28 10.7 0.0 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.11 KND92532.1 - 3.4e-49 167.4 39.2 3.4e-49 167.4 27.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND92532.1 - 4.4e-18 65.0 7.5 4.4e-18 65.0 5.2 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter DUF1228 PF06779.9 KND92532.1 - 0.0021 18.0 0.6 0.0021 18.0 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Rhabdo_glycop PF00974.13 KND92532.1 - 0.39 8.8 0.8 0.66 8.1 0.0 1.7 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Hist_deacetyl PF00850.14 KND92533.1 - 6.5e-89 298.2 0.0 1.1e-88 297.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KND92533.1 - 1.8e-43 148.0 0.9 2.7e-43 147.4 0.7 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.14 KND92534.1 - 6.4e-89 298.3 0.0 1.1e-88 297.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KND92534.1 - 4e-44 150.1 1.1 6e-44 149.5 0.8 1.2 1 0 0 1 1 1 1 Arb2 domain Nuc_sug_transp PF04142.10 KND92536.1 - 7.6e-77 257.6 3.8 1.2e-76 256.9 2.6 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KND92536.1 - 1.8e-09 37.4 21.8 4.1e-07 29.7 1.0 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KND92536.1 - 1e-08 34.4 10.2 5.6e-08 32.0 6.7 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KND92536.1 - 3.4e-06 27.1 3.7 3.4e-06 27.1 2.6 2.9 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KND92536.1 - 0.0036 17.4 2.7 0.0036 17.4 1.9 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KND92536.1 - 2.1 8.1 10.7 5.5 6.8 2.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 Ank_2 PF12796.2 KND92537.1 - 1e-59 198.8 9.2 5.7e-20 71.4 0.1 3.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KND92537.1 - 7.2e-32 107.6 3.5 1.7e-06 27.5 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KND92537.1 - 2.3e-25 88.0 2.7 1.2e-07 31.7 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND92537.1 - 1.7e-22 79.3 0.1 2.9e-07 30.8 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND92537.1 - 3.7e-22 76.1 0.7 0.0042 17.1 0.0 6.3 6 1 0 6 6 6 4 Ankyrin repeat Lactamase_B PF00753.22 KND92538.1 - 0.019 14.6 0.5 0.053 13.1 0.4 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DAO PF01266.19 KND92541.1 - 6.1e-36 124.0 0.1 7.7e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND92541.1 - 0.0029 17.4 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KND92541.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND92541.1 - 0.037 14.1 0.0 5.9 6.8 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Isochorismatase PF00857.15 KND92542.1 - 1.2e-17 64.4 0.0 1.9e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 KND92542.1 - 0.024 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbH NLPC_P60 PF00877.14 KND92543.1 - 9.8e-18 63.9 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.8 KND92543.1 - 0.00074 19.1 0.2 0.0014 18.2 0.1 1.5 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DUF1175 PF06672.6 KND92543.1 - 0.0016 17.8 0.2 0.27 10.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1175) MFS_1 PF07690.11 KND92544.1 - 1.4e-30 106.2 21.4 1.4e-30 106.2 14.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily NCU-G1 PF15065.1 KND92546.1 - 0.0013 17.5 1.2 0.0013 17.5 0.8 1.7 2 0 0 2 2 2 1 Lysosomal transcription factor, NCU-G1 SKG6 PF08693.5 KND92546.1 - 0.0018 17.5 2.2 0.0018 17.5 1.6 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.7 KND92546.1 - 0.0099 15.2 0.5 0.029 13.7 0.4 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Toxin_50 PF15530.1 KND92546.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 50 Glyco_hydro_1 PF00232.13 KND92547.1 - 1.3e-75 254.3 0.6 1.9e-73 247.2 0.4 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 ketoacyl-synt PF00109.21 KND92549.1 - 2e-80 269.9 0.0 5.2e-80 268.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND92549.1 - 9e-59 199.3 0.2 2.4e-58 197.9 0.1 1.8 1 1 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KND92549.1 - 5.3e-55 185.8 6.5 6.2e-55 185.6 1.5 3.0 3 1 0 3 3 1 1 KR domain PS-DH PF14765.1 KND92549.1 - 1.1e-54 185.6 0.0 1.8e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KND92549.1 - 1.8e-46 158.1 2.9 5.2e-45 153.3 0.2 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND92549.1 - 5.5e-40 135.9 0.1 1.4e-39 134.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KND92549.1 - 1.4e-21 76.3 0.1 7.1e-21 74.1 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KND92549.1 - 5.5e-19 68.4 0.0 1.6e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND92549.1 - 2.8e-14 53.1 0.0 6.2e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND92549.1 - 7.3e-09 35.3 0.0 4.4e-08 32.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND92549.1 - 4.3e-08 33.7 0.0 2e-07 31.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND92549.1 - 5.1e-08 33.2 0.0 1.8e-07 31.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KND92549.1 - 2.2e-06 27.3 0.1 4.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KND92549.1 - 3.1e-06 26.4 0.0 7.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 KND92549.1 - 1.5e-05 24.5 0.1 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 KND92549.1 - 2.7e-05 24.4 0.0 0.0021 18.3 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KND92549.1 - 5.1e-05 23.4 0.1 0.00018 21.6 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KND92549.1 - 7.5e-05 21.8 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.1 KND92549.1 - 0.0016 19.3 0.3 0.024 15.5 0.1 3.2 2 1 0 2 2 1 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.14 KND92549.1 - 0.0045 15.7 0.0 0.011 14.4 0.0 1.7 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.16 KND92549.1 - 0.012 15.4 0.3 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 ThiF family NAD_binding_10 PF13460.1 KND92549.1 - 0.014 15.3 1.1 0.033 14.1 0.1 2.2 2 0 0 2 2 1 0 NADH(P)-binding ACP_syn_III_C PF08541.5 KND92549.1 - 0.086 12.8 0.4 0.8 9.7 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TFIIE-A_C-term PF11521.3 KND92551.1 - 0.033 14.1 0.7 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha MFS_1 PF07690.11 KND92552.1 - 7e-37 126.9 47.0 7.8e-37 126.7 31.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily RNA_pol_Rpb1_5 PF04998.12 KND92554.1 - 1.1e-20 74.0 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 DSBA PF01323.15 KND92555.1 - 2.8e-20 72.7 0.0 3.3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Histone PF00125.19 KND92556.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KND92556.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KND92556.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KND92556.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KND92557.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KND92557.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KND92557.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KND92557.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KND92557.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KND92557.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1227 PF06777.6 KND92558.1 - 2.8e-62 208.7 1.1 5.2e-62 207.8 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KND92558.1 - 4.9e-46 156.2 0.0 1.2e-45 155.0 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KND92558.1 - 4.1e-43 147.2 0.0 1e-42 145.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KND92558.1 - 0.00011 21.1 0.0 0.00077 18.3 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KND92558.1 - 0.0076 15.7 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KND92558.1 - 0.053 13.3 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KND92558.1 - 0.085 12.4 0.1 0.39 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain zf-C2H2 PF00096.21 KND92559.1 - 1.1e-12 47.4 20.0 2.6e-05 24.2 1.2 4.1 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND92559.1 - 1.5e-09 37.4 19.0 0.0013 18.9 0.3 4.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND92559.1 - 9.8e-06 25.6 24.0 0.00014 21.9 1.8 4.3 4 1 1 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 KND92559.1 - 0.031 14.4 10.3 0.4 10.9 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.2 KND92559.1 - 0.066 13.4 5.5 11 6.3 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND92559.1 - 0.069 13.3 12.6 2.1 8.5 0.1 3.8 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KND92559.1 - 0.49 10.1 4.3 0.3 10.8 0.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 KND92559.1 - 0.64 10.4 10.8 1.1 9.6 0.7 3.4 2 1 2 4 4 4 0 TRAF-type zinc finger zf-BED PF02892.10 KND92559.1 - 4.2 7.2 10.4 2.5 7.9 2.7 3.1 2 1 1 3 3 3 0 BED zinc finger PRP3 PF08572.5 KND92560.1 - 9.9e-52 175.5 10.7 3.6e-50 170.4 7.4 2.5 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KND92560.1 - 6.2e-38 129.3 0.4 1.8e-37 127.8 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 KND92561.1 - 1.7e-65 221.0 0.4 3.1e-65 220.1 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KND92561.1 - 2.6e-64 216.1 0.3 6e-64 214.9 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KND92561.1 - 2.9e-24 85.5 0.0 1.6e-23 83.2 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KND92561.1 - 2.6e-19 69.6 7.4 2.2e-11 43.6 0.1 4.8 2 1 2 4 4 4 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KND92561.1 - 2.5e-17 62.5 0.0 1.1e-16 60.4 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FTCD PF02971.9 KND92562.1 - 0.17 11.4 0.9 0.43 10.2 0.2 1.8 2 0 0 2 2 2 0 Formiminotransferase domain FF PF01846.14 KND92563.1 - 4.3e-12 45.7 8.8 9.3e-08 31.9 0.2 3.1 3 0 0 3 3 3 2 FF domain WW PF00397.21 KND92563.1 - 1.9e-09 37.1 3.1 5.7e-09 35.6 2.2 1.9 1 0 0 1 1 1 1 WW domain TTSSLRR PF12468.3 KND92563.1 - 0.029 13.9 2.3 0.13 11.7 1.6 2.2 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DDHD PF02862.12 KND92565.1 - 1.1e-37 130.0 0.0 4.5e-21 75.6 0.0 2.6 2 0 0 2 2 2 2 DDHD domain Abhydrolase_6 PF12697.2 KND92565.1 - 0.00039 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92565.1 - 0.035 13.8 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 KND92565.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Amidoligase_2 PF12224.3 KND92566.1 - 5e-18 65.6 0.0 3.6e-14 53.0 0.0 2.5 2 1 0 2 2 2 2 Putative amidoligase enzyme Hira PF07569.6 KND92567.1 - 5.1e-83 277.5 0.0 1.4e-82 276.1 0.0 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KND92567.1 - 5.2e-45 149.7 15.7 3.5e-07 29.8 0.1 8.9 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 KND92567.1 - 9.2e-09 34.6 0.6 2.2e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KND92567.1 - 0.0079 15.8 6.1 37 4.1 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KND92567.1 - 0.23 9.2 0.0 1.1 7.0 0.0 2.0 1 1 1 2 2 2 0 IKI3 family Sugar_tr PF00083.19 KND92568.1 - 7.8e-72 242.2 13.2 2.6e-53 181.2 1.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KND92568.1 - 1.9e-22 79.4 17.5 6.4e-20 71.1 12.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF336 PF03928.9 KND92569.1 - 2.3e-18 66.2 0.3 3.2e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Glyco_transf_15 PF01793.11 KND92572.1 - 2e-58 197.9 0.0 3.5e-58 197.1 0.0 1.2 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sas10_Utp3 PF04000.10 KND92573.1 - 8.8e-14 51.4 2.4 9.6e-14 51.3 0.2 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family HCaRG PF07258.9 KND92573.1 - 0.00096 18.7 2.0 0.0014 18.1 1.4 1.3 1 0 0 1 1 1 1 HCaRG protein UPF0172 PF03665.8 KND92573.1 - 0.043 13.3 1.5 0.054 12.9 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) RNA_polI_A14 PF08203.6 KND92573.1 - 0.48 10.6 3.0 2.3 8.5 0.0 3.0 3 1 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 NTP_transferase PF00483.18 KND92574.1 - 7.1e-29 100.8 0.0 1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KND92574.1 - 1.6e-08 33.6 10.8 2.7e-05 23.4 0.2 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KND92574.1 - 9.1e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2968 PF11180.3 KND92574.1 - 0.19 11.1 0.3 0.28 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Dynamin_N PF00350.18 KND92575.1 - 9.6e-19 67.8 0.0 5.3e-18 65.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND92575.1 - 3.9e-09 35.7 0.1 2.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KND92575.1 - 0.00012 21.8 1.3 0.00023 20.9 0.2 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.22 KND92575.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 KND92575.1 - 0.069 13.6 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KND92575.1 - 0.17 11.8 0.0 2 8.4 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.11 KND92576.1 - 1.6e-16 59.9 13.9 3.2e-10 39.2 0.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Reo_P9 PF06043.6 KND92576.1 - 0.028 13.4 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Reovirus P9-like family DUF1772 PF08592.6 KND92576.1 - 3 7.5 11.8 0.14 11.9 0.4 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) ABC2_membrane PF01061.19 KND92577.1 - 1.8e-85 285.3 64.1 1.3e-43 148.6 19.1 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KND92577.1 - 7e-37 126.7 0.0 1.7e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KND92577.1 - 2.7e-31 107.2 10.3 1.2e-27 95.5 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KND92577.1 - 2.7e-19 69.0 0.0 7.3e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KND92577.1 - 7.1e-11 41.8 0.1 9.8e-06 25.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND92577.1 - 2.4e-06 27.6 0.3 0.00073 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KND92577.1 - 1.1e-05 24.6 0.0 0.0038 16.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KND92577.1 - 2.3e-05 23.8 0.5 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KND92577.1 - 2.4e-05 23.8 2.4 0.001 18.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KND92577.1 - 4.9e-05 23.2 0.6 0.0079 16.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KND92577.1 - 5.1e-05 23.5 0.1 0.0052 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND92577.1 - 0.00015 22.6 0.0 0.04 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KND92577.1 - 0.00091 19.7 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein SMC_N PF02463.14 KND92577.1 - 0.0012 18.1 0.0 0.88 8.7 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KND92577.1 - 0.0018 18.3 0.1 0.29 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KND92577.1 - 0.0032 17.1 1.6 0.99 9.0 0.2 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 KND92577.1 - 0.013 15.4 0.0 8 6.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.1 KND92577.1 - 0.02 14.8 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KND92577.1 - 0.032 13.9 1.1 9.4 6.0 0.2 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 KND92577.1 - 0.04 13.8 0.4 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KND92577.1 - 0.04 14.2 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KND92577.1 - 0.048 13.8 0.1 11 6.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KND92577.1 - 0.087 13.0 0.1 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KND92577.1 - 0.25 10.9 2.4 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 KND92577.1 - 0.53 9.2 0.0 1.3 8.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KND92577.1 - 0.97 8.8 2.7 20 4.5 0.1 2.9 3 0 0 3 3 3 0 AAA-like domain FMN_red PF03358.10 KND92578.1 - 2.7e-05 23.7 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Glyoxalase PF00903.20 KND92579.1 - 1.1e-15 57.7 0.0 1.3e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KND92579.1 - 1.1e-13 51.7 0.2 1.3e-13 51.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KND92579.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KND92579.1 - 6.2e-05 22.9 0.4 0.017 15.0 0.2 2.4 1 1 0 1 1 1 1 Glyoxalase-like domain PTH2 PF01981.11 KND92580.1 - 3.1e-46 155.8 0.0 4e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribonuclease_3 PF00636.21 KND92581.1 - 5.5e-32 110.5 0.0 7.9e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain DEAD PF00270.24 KND92581.1 - 2.3e-18 66.2 0.1 4.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribonucleas_3_3 PF14622.1 KND92581.1 - 1.1e-14 54.4 0.0 0.00014 21.7 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 KND92581.1 - 5.3e-14 51.8 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KND92581.1 - 7.1e-13 48.1 0.2 3.5e-12 45.9 0.0 2.3 3 0 0 3 3 3 1 Dicer dimerisation domain ResIII PF04851.10 KND92581.1 - 9.1e-11 41.9 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 KND92581.1 - 0.00068 20.1 0.1 0.0018 18.8 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DEAD_2 PF06733.10 KND92581.1 - 0.0036 16.7 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 RCC1_2 PF13540.1 KND92582.1 - 7.7e-11 41.3 8.0 5.9e-08 32.1 0.2 4.7 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KND92582.1 - 7.1e-10 38.9 1.5 0.015 15.4 0.1 5.3 4 2 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat AMP-binding PF00501.23 KND92583.1 - 1.2e-69 234.7 0.0 1.7e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Asp PF00026.18 KND92583.1 - 1.7e-54 185.2 0.0 2.3e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AMP-binding_C PF13193.1 KND92583.1 - 1.9e-11 44.7 1.6 8e-11 42.7 1.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TAXi_N PF14543.1 KND92583.1 - 5.5e-08 32.9 0.0 5.5e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND92583.1 - 0.00032 21.1 0.1 10 6.7 0.0 3.6 3 0 0 3 3 3 2 Aspartyl protease CFEM PF05730.6 KND92584.1 - 0.00013 21.7 2.1 0.00013 21.7 1.5 3.3 3 0 0 3 3 3 1 CFEM domain Dynamin_N PF00350.18 KND92585.1 - 8.2e-34 116.8 0.2 1.6e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND92585.1 - 6.4e-17 61.2 0.0 9.2e-15 54.1 0.0 2.7 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KND92585.1 - 6.6e-06 26.0 0.0 3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND92585.1 - 0.0007 20.0 0.1 0.0034 17.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 KND92585.1 - 0.0056 16.5 0.3 0.096 12.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_21 PF13304.1 KND92585.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KND92585.1 - 0.035 14.4 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KND92585.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AHH PF14412.1 KND92585.1 - 0.15 12.1 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH FeoB_N PF02421.13 KND92585.1 - 0.16 11.2 0.1 14 4.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B APH PF01636.18 KND92586.1 - 0.003 17.3 0.1 0.003 17.3 0.0 3.7 3 2 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 KND92586.1 - 0.0056 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HSDR_N_2 PF13588.1 KND92586.1 - 0.018 14.8 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) ARGLU PF15346.1 KND92586.1 - 2.2 8.0 45.2 6.2 6.5 31.3 1.8 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Ank_5 PF13857.1 KND92587.1 - 5.6e-05 23.2 0.1 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3435 PF11917.3 KND92588.1 - 1.1e-58 198.9 0.1 2.7e-58 197.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Methyltransf_23 PF13489.1 KND92589.1 - 7.4e-21 74.5 0.2 1.3e-20 73.7 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND92589.1 - 7.6e-09 35.3 0.2 7.7e-08 32.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND92589.1 - 1.2e-06 29.0 0.3 2e-05 25.1 0.2 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND92589.1 - 2.2e-05 24.7 0.0 8.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND92589.1 - 0.0001 22.7 0.0 0.00085 19.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KND92589.1 - 0.017 15.0 0.0 0.021 14.8 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 KND92589.1 - 0.03 14.8 0.0 0.18 12.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KND92589.1 - 0.032 14.2 0.0 0.086 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF4231 PF14015.1 KND92589.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) APH PF01636.18 KND92590.1 - 7.1e-14 52.1 0.4 1.1e-13 51.5 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND92590.1 - 7e-05 22.4 0.0 9.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KND92590.1 - 0.013 14.1 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 KND92590.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KND92590.1 - 0.18 10.9 0.0 3 6.9 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.20 KND92591.1 - 1.2e-14 54.1 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KND92591.1 - 3.6e-08 32.7 0.0 5.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND92591.1 - 5.6e-08 32.8 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KND92591.1 - 6.6e-07 28.6 0.0 8.3e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KND92591.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KND92591.1 - 0.0011 18.0 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KND92591.1 - 0.012 14.4 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KND92591.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.6 KND92591.1 - 0.041 13.1 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) CysG_dimeriser PF10414.4 KND92591.1 - 0.18 11.3 0.3 0.37 10.2 0.0 1.6 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region zf-H2C2_2 PF13465.1 KND92592.1 - 1e-09 38.1 17.5 1.5e-05 25.0 1.0 4.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KND92592.1 - 2.2e-09 37.1 31.1 0.00016 21.8 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND92592.1 - 2e-05 24.6 25.1 0.0049 17.1 0.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger Mito_carr PF00153.22 KND92593.1 - 9.3e-61 201.5 1.4 4.6e-20 71.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein THEG PF14912.1 KND92594.1 - 0.075 13.5 0.0 12 6.5 0.0 2.7 2 0 0 2 2 2 0 Testicular haploid expressed repeat PH PF00169.24 KND92596.1 - 2.4e-28 98.3 4.5 9.1e-16 57.9 0.2 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KND92596.1 - 3.9e-13 49.6 6.6 7.4e-08 32.6 0.1 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KND92596.1 - 2.8e-10 40.3 3.9 2.8e-06 27.4 0.6 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KND92596.1 - 6.9e-05 22.8 0.1 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KND92596.1 - 0.0034 17.2 2.1 0.028 14.2 0.2 2.7 2 1 1 3 3 3 1 PH domain WD40 PF00400.27 KND92597.1 - 1.1e-18 66.3 4.3 3.6e-10 39.3 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KND92597.1 - 0.012 14.4 0.3 1.6 7.3 0.3 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 KND92597.1 - 0.062 11.4 0.0 0.34 8.9 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribonuc_red_sm PF00268.16 KND92598.1 - 1.2e-117 391.9 2.8 1.5e-117 391.6 1.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 KND92599.1 - 1.2e-22 79.3 0.6 2.9e-21 75.0 0.4 2.1 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF834 PF05754.9 KND92599.1 - 6.7 6.5 10.2 11 5.8 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF834) DCP2 PF05026.8 KND92600.1 - 1.1e-36 124.5 1.0 1.1e-36 124.5 0.7 2.1 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 KND92600.1 - 3e-15 56.0 0.0 7.5e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 KND92601.1 - 1.5e-33 114.8 0.2 1.9e-33 114.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2076 PF09849.4 KND92604.1 - 2.5e-08 34.2 14.3 3.1e-08 33.9 9.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KND92604.1 - 0.0019 18.0 6.6 0.0032 17.3 4.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KND92604.1 - 0.031 14.3 1.3 0.049 13.7 0.2 1.6 1 1 1 2 2 2 0 GCK domain DUF605 PF04652.11 KND92604.1 - 0.82 9.0 13.8 1 8.6 9.6 1.1 1 0 0 1 1 1 0 Vta1 like COX17 PF05051.8 KND92604.1 - 0.99 9.4 3.8 0.93 9.5 0.5 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) zinc-ribbons_6 PF07191.7 KND92604.1 - 6.5 6.6 8.7 14 5.5 6.0 1.5 1 1 0 1 1 1 0 zinc-ribbons UBX PF00789.15 KND92605.1 - 1.6e-12 47.3 0.0 2.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 KND92605.1 - 0.12 12.4 0.1 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Atg14 PF10186.4 KND92605.1 - 0.17 10.8 7.9 0.25 10.2 5.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 eIF-5_eIF-2B PF01873.12 KND92606.1 - 4.3e-38 129.7 0.0 1.7e-37 127.8 0.0 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 KND92606.1 - 6.6e-25 86.8 0.7 6.6e-25 86.8 0.5 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon efThoc1 PF11957.3 KND92607.1 - 1.8e-139 465.4 4.9 1.8e-139 465.4 3.4 2.9 2 1 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KND92607.1 - 4.1e-37 127.4 0.0 1.1e-36 126.0 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 KND92607.1 - 0.00035 20.6 0.4 0.0019 18.2 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND92607.1 - 0.001 19.2 0.0 0.0049 17.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND92607.1 - 0.0019 18.0 0.0 0.0067 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND92607.1 - 0.0023 18.7 2.1 0.021 15.6 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KND92607.1 - 0.0034 17.6 0.0 0.032 14.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KND92607.1 - 0.0039 17.1 0.9 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KND92607.1 - 0.0067 16.1 0.0 0.0067 16.1 0.0 2.9 5 0 0 5 5 5 1 Archaeal ATPase AAA_33 PF13671.1 KND92607.1 - 0.0084 15.9 0.3 0.076 12.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KND92607.1 - 0.013 15.2 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 1 0 NTPase AAA_5 PF07728.9 KND92607.1 - 0.019 14.7 0.0 0.064 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KND92607.1 - 0.021 14.0 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 KND92607.1 - 0.022 15.2 0.7 0.11 13.0 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein MobB PF03205.9 KND92607.1 - 0.04 13.6 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KND92607.1 - 0.1 12.5 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase HEAT PF02985.17 KND92608.1 - 1.4e-37 124.3 12.9 0.0067 16.4 0.0 12.7 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 KND92608.1 - 1.8e-23 82.5 6.0 3e-07 30.6 0.0 7.2 5 2 1 6 6 5 4 HEAT repeats Vac14_Fab1_bd PF12755.2 KND92608.1 - 1.6e-10 41.2 4.6 0.26 11.7 0.1 6.5 6 1 1 7 7 7 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KND92608.1 - 5.9e-10 39.3 8.7 0.022 15.2 0.0 7.6 9 1 1 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KND92608.1 - 0.00019 19.8 8.5 0.00059 18.2 0.1 3.6 4 1 0 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.3 KND92608.1 - 0.00034 20.0 0.8 3 7.1 0.0 4.4 3 2 2 5 5 5 1 CLASP N terminal DUF2435 PF10363.4 KND92608.1 - 0.0008 19.2 5.5 0.023 14.5 0.2 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 KND92608.1 - 0.012 15.4 0.6 1.9 8.4 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 KND92608.1 - 0.021 13.8 0.0 0.28 10.1 0.0 2.4 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.4 KND92608.1 - 0.21 9.7 2.7 0.72 8.0 0.1 2.7 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KND92608.1 - 1.2 8.9 6.6 10 5.9 0.1 4.7 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Myotub-related PF06602.9 KND92609.1 - 2.4e-128 427.8 0.1 3.1e-128 427.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KND92609.1 - 0.032 14.4 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KND92609.1 - 0.054 12.8 0.0 0.23 10.7 0.0 2.0 2 1 0 2 2 2 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 KND92610.1 - 1.2e-16 60.6 0.1 2.6e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KND92610.1 - 1e-10 41.0 0.0 1.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KND92610.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 KND92611.1 - 8.6e-101 336.8 12.2 4.7e-100 334.4 6.1 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KND92611.1 - 5.8e-09 36.1 1.5 5.8e-09 36.1 1.0 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KND92611.1 - 0.00014 21.8 7.4 0.00014 21.8 5.1 3.3 2 1 1 3 3 3 1 EamA-like transporter family p450 PF00067.17 KND92612.1 - 3.2e-43 147.9 0.0 1.4e-39 135.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 eIF-6 PF01912.13 KND92614.1 - 1.3e-83 278.9 1.0 1.8e-83 278.4 0.7 1.2 1 0 0 1 1 1 1 eIF-6 family Methyltransf_18 PF12847.2 KND92615.1 - 2.8e-19 69.7 0.1 4.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND92615.1 - 9.6e-15 54.4 0.0 1.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND92615.1 - 5.3e-09 36.4 0.0 1.1e-08 35.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND92615.1 - 3.1e-08 33.6 0.2 9.1e-08 32.1 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND92615.1 - 8.8e-06 26.1 0.1 2.6e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND92615.1 - 1.4e-05 24.9 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND92615.1 - 3.7e-05 24.0 0.0 6.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND92615.1 - 0.00017 20.9 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KND92615.1 - 0.00027 20.3 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 KND92615.1 - 0.00032 19.8 0.0 0.0067 15.5 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KND92615.1 - 0.00042 20.0 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND92615.1 - 0.01 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AdoMet_MTase PF07757.8 KND92615.1 - 0.013 15.5 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Acetyltransf_8 PF13523.1 KND92616.1 - 7e-42 142.8 0.8 1.1e-41 142.3 0.6 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND92616.1 - 0.023 14.8 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.14 KND92617.1 - 3.2e-54 184.1 0.0 4.3e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND92617.1 - 2.6e-38 131.5 0.0 4.1e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND92617.1 - 2.2e-05 23.4 0.0 0.14 11.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KND92617.1 - 0.00035 19.6 0.0 0.00054 18.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KND92617.1 - 0.00085 18.3 0.8 0.0038 16.1 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND92617.1 - 0.0026 17.7 0.1 0.008 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KND92617.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Aldedh PF00171.17 KND92618.1 - 2.7e-151 504.0 0.0 3.2e-151 503.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.23 KND92619.1 - 1.5e-246 817.5 0.0 7.7e-87 291.3 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KND92619.1 - 8.4e-181 599.4 0.5 3e-33 114.9 0.0 8.4 8 1 0 8 8 8 7 Condensation domain PP-binding PF00550.20 KND92619.1 - 2.1e-51 172.0 12.9 5.4e-10 39.3 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site WES_acyltransf PF03007.11 KND92619.1 - 2.9e-08 33.6 1.0 0.018 14.5 0.0 4.9 5 0 0 5 5 5 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.10 KND92619.1 - 0.051 12.0 0.0 19 3.5 0.0 3.5 3 0 0 3 3 3 0 Transferase family DUF1479 PF07350.7 KND92620.1 - 8.1e-93 311.1 0.0 9.6e-93 310.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Zn_clus PF00172.13 KND92621.1 - 1.5e-06 27.9 8.7 2.7e-06 27.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K_oxygenase PF13434.1 KND92622.1 - 3.6e-104 348.3 0.0 4.8e-104 347.9 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KND92622.1 - 4.8e-09 36.5 0.0 3.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND92622.1 - 1.5e-08 34.5 0.3 2.2e-06 27.5 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND92622.1 - 8e-07 29.1 0.0 0.00011 22.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND92622.1 - 0.037 12.9 0.1 4.6 6.0 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein IF-2B PF01008.12 KND92623.1 - 1.9e-23 82.8 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KND92623.1 - 8.2e-07 28.7 0.0 6.8e-05 22.5 0.0 3.0 2 1 1 3 3 3 1 NUDIX domain PALP PF00291.20 KND92623.1 - 0.0055 15.9 0.6 0.077 12.2 0.1 2.2 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme AAA_17 PF13207.1 KND92625.1 - 0.0024 18.6 0.0 0.0081 16.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 KND92625.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Xpo1 PF08389.7 KND92626.1 - 5.7e-06 26.3 0.4 5.7e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 Exportin 1-like protein DUF4045 PF13254.1 KND92626.1 - 0.028 13.7 0.2 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Sec15 PF04091.7 KND92627.1 - 1.3e-116 389.3 5.3 1.3e-116 389.3 3.7 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 KND92627.1 - 0.0045 16.4 2.9 0.0045 16.4 2.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) COG5 PF10392.4 KND92627.1 - 0.0093 15.9 5.8 0.1 12.5 0.5 3.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DIL PF01843.14 KND92627.1 - 0.035 13.9 0.0 0.21 11.5 0.0 2.3 1 0 0 1 1 1 0 DIL domain Fcf2 PF08698.6 KND92628.1 - 5.3e-25 87.3 0.0 1.3e-24 86.1 0.0 1.6 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing SAM_2 PF07647.12 KND92629.1 - 2e-10 40.3 0.1 3.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KND92629.1 - 1e-05 25.5 0.2 2.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KND92629.1 - 0.15 11.9 0.1 0.43 10.5 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif Sad1_UNC PF07738.8 KND92630.1 - 8.3e-35 119.5 0.0 1.4e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal TPR_11 PF13414.1 KND92631.1 - 6.9e-18 64.0 24.5 0.00074 19.1 0.0 7.2 6 1 1 7 7 7 5 TPR repeat TPR_16 PF13432.1 KND92631.1 - 4.1e-13 49.6 32.8 6e-07 29.9 0.1 7.1 8 1 1 9 9 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KND92631.1 - 6.4e-10 38.4 1.7 0.67 10.3 0.1 6.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND92631.1 - 1.3e-09 37.8 29.4 0.0047 17.4 0.1 9.8 8 3 2 10 10 10 3 Tetratricopeptide repeat TPR_20 PF14561.1 KND92631.1 - 8.8e-08 32.1 11.7 0.029 14.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KND92631.1 - 1.3e-07 31.8 22.5 0.0003 21.0 0.0 7.4 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND92631.1 - 3.9e-07 29.8 23.7 0.00027 20.8 0.1 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND92631.1 - 5.6e-06 25.8 28.9 0.39 10.7 0.0 10.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND92631.1 - 0.00036 20.0 0.4 1.3 8.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND92631.1 - 0.0023 17.4 13.9 22 4.8 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KND92631.1 - 0.081 13.1 1.1 3.8 7.7 0.0 3.2 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_7 PF13176.1 KND92631.1 - 0.13 12.0 16.4 3.3 7.7 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND92631.1 - 0.79 9.6 17.5 1.4 8.8 0.6 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND92631.1 - 9.5 6.3 18.7 0.78 9.7 2.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.18 KND92632.1 - 1.3e-19 69.9 0.6 2.1e-19 69.3 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND92632.1 - 4.4e-12 45.9 1.2 5.9e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KND92632.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Mito_carr PF00153.22 KND92633.1 - 3.5e-55 183.6 0.4 9.5e-19 66.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.12 KND92633.1 - 2.5e-20 72.0 7.0 4.4e-20 71.2 4.9 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.17 KND92634.1 - 3.5e-56 186.7 0.1 6.4e-21 73.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND92634.1 - 5.1e-39 132.0 0.5 1e-12 47.8 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND92634.1 - 4e-28 97.0 0.0 6.2e-10 38.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND92634.1 - 1.1e-05 25.1 0.0 0.13 12.0 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 KND92634.1 - 0.015 15.2 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2868 PF11067.3 KND92635.1 - 0.13 11.3 1.3 0.17 10.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MRI PF15325.1 KND92635.1 - 0.94 10.4 7.4 1.5 9.8 5.1 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection UL73_N PF12522.3 KND92635.1 - 6.5 6.3 8.2 11 5.7 3.5 2.3 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Tubulin_3 PF14881.1 KND92636.1 - 2.3e-76 255.3 0.1 3.7e-76 254.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KND92636.1 - 1.1e-39 135.0 0.1 1.8e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KND92636.1 - 3.4e-06 27.0 0.0 0.00094 19.0 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF1839 PF08893.5 KND92636.1 - 0.025 13.5 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) AhpC-TSA_2 PF13911.1 KND92637.1 - 9.2e-12 44.9 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KND92637.1 - 3.4e-05 23.5 0.0 5.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND92637.1 - 0.00073 19.0 0.0 0.02 14.4 0.0 2.2 1 1 0 1 1 1 1 Redoxin Septin PF00735.13 KND92638.1 - 7.7e-11 41.5 0.0 2.6e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Septin Pkinase PF00069.20 KND92639.1 - 8e-77 257.8 0.0 9.6e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92639.1 - 8.1e-38 129.9 0.0 1.1e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND92639.1 - 0.005 15.8 0.0 0.013 14.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KND92639.1 - 0.099 12.3 2.1 0.38 10.4 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Acyltransferase PF01553.16 KND92640.1 - 3.2e-10 39.5 0.0 4.3e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 KND92641.1 - 3e-09 36.7 13.4 5.1e-05 23.2 3.2 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND92641.1 - 5.6e-09 35.6 11.9 7.1e-06 25.7 3.2 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KND92641.1 - 3.9e-06 26.4 5.7 3.9e-06 26.4 3.9 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND92641.1 - 3.7e-05 23.2 14.3 0.0051 16.4 4.2 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND92641.1 - 0.00021 21.1 16.6 0.0056 16.5 5.5 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND92641.1 - 0.00031 20.3 8.3 0.00066 19.3 3.8 2.6 2 0 0 2 2 2 1 RING-type zinc-finger FYVE PF01363.16 KND92641.1 - 0.003 17.4 10.0 0.011 15.6 3.2 2.7 2 1 1 3 3 3 1 FYVE zinc finger Rtf2 PF04641.7 KND92641.1 - 0.012 14.8 1.6 0.012 14.8 1.1 2.4 2 1 1 3 3 3 0 Rtf2 RING-finger zf-rbx1 PF12678.2 KND92641.1 - 1.1 9.4 7.1 0.49 10.5 2.3 2.4 2 1 1 3 3 3 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KND92641.1 - 2.6 7.9 6.5 0.46 10.3 1.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CHY PF05495.7 KND92641.1 - 3.2 7.9 9.9 2.3 8.4 2.7 2.8 2 1 1 3 3 3 0 CHY zinc finger IBR PF01485.16 KND92641.1 - 4.3 7.2 14.4 0.83 9.5 1.9 3.4 2 1 1 3 3 3 0 IBR domain Mito_carr PF00153.22 KND92642.1 - 3.3e-32 110.0 0.5 3.1e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein SCA7 PF08313.7 KND92643.1 - 1.4e-34 117.4 0.3 4.2e-34 115.9 0.2 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Lipase_GDSL_2 PF13472.1 KND92643.1 - 3.3e-16 59.9 0.0 1.3e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF3505 PF12013.3 KND92643.1 - 0.13 12.5 2.5 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) CDC45 PF02724.9 KND92643.1 - 0.65 7.9 9.2 0.94 7.4 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Fork_head PF00250.13 KND92644.1 - 2.9e-31 107.3 0.5 5.2e-31 106.5 0.3 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KND92644.1 - 4.6e-09 36.2 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain PAP_central PF04928.12 KND92645.1 - 9.6e-101 335.8 0.0 1.3e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KND92645.1 - 1.3e-47 161.2 1.6 2.8e-47 160.1 0.2 2.0 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KND92645.1 - 2.4e-07 31.0 0.1 5.8e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain SPOC PF07744.8 KND92646.1 - 7.7e-21 74.7 0.0 1.6e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 KND92646.1 - 1e-16 60.9 0.1 1e-16 60.9 0.1 2.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KND92646.1 - 3e-08 33.2 9.5 5.5e-08 32.3 6.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KND92646.1 - 3.8 6.9 7.3 7.1 6.0 5.1 1.4 1 0 0 1 1 1 0 PHD-finger CMS1 PF14617.1 KND92647.1 - 4.5e-87 291.2 1.3 5e-87 291.1 0.9 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KND92647.1 - 4.2e-07 29.6 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Consortin_C PF15281.1 KND92647.1 - 0.067 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Consortin C-terminus CHD5 PF04420.9 KND92648.1 - 2e-54 183.6 0.1 2.6e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein MMS19_N PF14500.1 KND92648.1 - 0.02 14.1 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Phlebovirus_NSM PF07246.6 KND92648.1 - 0.076 12.1 0.1 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Abhydrolase_6 PF12697.2 KND92649.1 - 1e-24 87.6 9.0 1.3e-24 87.3 6.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92649.1 - 1.7e-14 53.8 2.4 4.8e-14 52.3 1.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KND92649.1 - 1.7e-07 30.8 0.1 0.0093 15.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KND92649.1 - 1.4e-05 24.7 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KND92649.1 - 2.9e-05 24.4 0.1 6.8e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KND92649.1 - 0.0013 18.2 0.1 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 KND92649.1 - 0.098 11.9 0.2 0.22 10.7 0.1 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family FAD_binding_3 PF01494.14 KND92650.1 - 2e-23 83.0 0.5 4.5e-11 42.4 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 KND92650.1 - 1.2e-05 24.3 0.0 8.8e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KND92650.1 - 5.6e-05 22.2 0.2 0.00076 18.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND92650.1 - 0.00021 21.2 0.1 0.00072 19.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND92650.1 - 0.00028 20.8 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND92650.1 - 0.00082 18.3 0.0 0.0027 16.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KND92650.1 - 0.0011 17.5 0.1 0.0016 16.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KND92650.1 - 0.0024 18.2 0.1 0.01 16.2 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND92650.1 - 0.01 14.7 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 KND92650.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KND92650.1 - 0.051 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KND92650.1 - 0.057 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KND92650.1 - 0.1 11.2 0.0 4.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase S_100 PF01023.14 KND92650.1 - 0.2 10.9 0.8 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Peptidase_C12 PF01088.16 KND92651.1 - 8.2e-54 182.0 0.0 1.1e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sugar_tr PF00083.19 KND92652.1 - 5.5e-112 374.6 20.2 6.4e-112 374.3 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND92652.1 - 2.1e-24 85.8 30.9 2.1e-24 85.8 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 KND92652.1 - 0.0045 15.6 0.4 0.0045 15.6 0.2 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF2420 PF10336.4 KND92653.1 - 0.3 10.6 1.7 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Apc4 PF12896.2 KND92654.1 - 4.4e-53 179.7 0.0 7.1e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Adap_comp_sub PF00928.16 KND92654.1 - 2.3e-15 56.4 0.0 4.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KND92654.1 - 8.1e-08 32.0 0.1 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_6 PF14259.1 KND92655.1 - 6.5e-38 128.5 0.0 1.3e-08 34.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND92655.1 - 1.7e-36 123.6 0.0 5.9e-12 45.0 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND92655.1 - 3.8e-20 71.4 0.1 0.00013 21.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KND92655.1 - 1.9e-11 43.3 4.3 1.9e-11 43.3 3.0 3.1 3 1 0 3 3 3 1 Putative RRM domain RNA_bind PF08675.6 KND92655.1 - 0.0053 16.7 0.0 0.034 14.1 0.0 2.4 3 0 0 3 3 3 1 RNA binding domain RRM_3 PF08777.6 KND92655.1 - 0.027 14.3 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 KND92655.1 - 0.04 13.6 0.0 13 5.6 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Abhydrolase_6 PF12697.2 KND92657.1 - 0.001 19.0 1.3 0.001 19.0 0.9 2.5 2 2 0 2 2 2 1 Alpha/beta hydrolase family SP2 PF03014.9 KND92657.1 - 0.0059 14.5 1.7 0.011 13.5 1.2 1.4 1 0 0 1 1 1 1 Structural protein 2 LCAT PF02450.10 KND92657.1 - 0.018 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 KND92657.1 - 0.14 11.7 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF676 PF05057.9 KND92657.1 - 0.36 10.1 0.0 0.58 9.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) His_Phos_2 PF00328.17 KND92658.1 - 1.4e-18 67.3 0.0 4.9e-17 62.2 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.7 KND92661.1 - 1.3e-70 237.1 0.1 1.6e-70 236.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KND92661.1 - 6.9e-05 23.3 0.0 0.0015 18.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KND92661.1 - 0.0039 16.4 0.0 0.0081 15.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Yippee-Mis18 PF03226.9 KND92663.1 - 6.7e-23 80.5 1.0 7.6e-23 80.3 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 KND92663.1 - 0.0077 16.2 2.5 0.021 14.8 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) HNH_5 PF14279.1 KND92663.1 - 0.0079 16.1 0.4 0.35 10.9 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Evr1_Alr PF04777.8 KND92663.1 - 0.031 14.1 3.4 0.19 11.6 0.5 2.2 1 1 1 2 2 2 0 Erv1 / Alr family zf-CHY PF05495.7 KND92663.1 - 0.032 14.3 2.0 4.7 7.4 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger RIG-I_C-RD PF11648.3 KND92663.1 - 0.072 12.9 2.3 0.17 11.7 1.6 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF3268 PF11672.3 KND92663.1 - 0.16 12.0 1.3 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) DUF4452 PF14618.1 KND92664.1 - 9.9e-75 249.9 10.7 1.2e-74 249.6 7.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Abhydrolase_6 PF12697.2 KND92665.1 - 3.5e-20 72.8 3.3 6.8e-20 71.9 2.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92665.1 - 1.6e-08 34.4 0.1 4.1e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND92665.1 - 8.8e-05 22.1 0.8 0.00025 20.6 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KND92665.1 - 0.00032 20.4 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KND92665.1 - 0.04 13.5 0.3 0.11 12.1 0.2 1.6 2 0 0 2 2 2 0 Lipase (class 3) ATP_bind_3 PF01171.15 KND92667.1 - 3.5e-38 130.9 0.0 4.9e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 KND92667.1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 KND92667.1 - 0.18 10.3 0.0 0.38 9.2 0.0 1.5 2 0 0 2 2 2 0 tRNA methyl transferase DUF4098 PF13345.1 KND92669.1 - 0.0083 16.0 14.4 0.26 11.2 0.1 6.0 6 1 0 6 6 6 2 Domain of unknown function (DUF4098) DUF2154 PF09922.4 KND92669.1 - 0.098 12.3 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Cell wall-active antibiotics response protein (DUF2154) Cyclin_N PF00134.18 KND92671.1 - 4.2e-10 39.2 0.1 9.1e-10 38.1 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Turandot PF07240.6 KND92671.1 - 0.1 12.1 0.2 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Mito_carr PF00153.22 KND92672.1 - 2.4e-68 225.8 5.5 2.5e-25 87.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KND92672.1 - 2.3e-25 88.5 6.7 8.9e-14 51.3 1.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KND92672.1 - 5.8e-20 69.0 12.1 1.5e-06 27.0 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.1 KND92672.1 - 1.4e-16 58.9 14.0 5.8e-05 22.2 0.2 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KND92672.1 - 1.7e-16 58.5 11.5 9.7e-06 25.0 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KND92672.1 - 7.4e-13 47.8 12.2 5.7e-07 29.0 0.6 3.6 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KND92672.1 - 2.5e-07 30.7 0.2 0.0015 18.5 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KND92672.1 - 0.023 14.5 0.4 6.9 6.6 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain EF-hand_10 PF14788.1 KND92672.1 - 0.099 12.3 0.9 27 4.5 0.0 3.2 4 0 0 4 4 4 0 EF hand Cullin_binding PF03556.10 KND92672.1 - 0.11 12.5 0.3 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Cullin binding HSP70 PF00012.15 KND92674.1 - 4.2e-08 31.5 0.1 3.5e-07 28.5 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein Pkinase PF00069.20 KND92675.1 - 8.4e-59 198.8 0.0 1.1e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92675.1 - 1.6e-31 109.3 0.0 6.4e-30 104.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND92675.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 KND92675.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1387) Stc1 PF12898.2 KND92676.1 - 1.3e-14 54.0 3.1 2.6e-14 53.0 2.2 1.5 1 0 0 1 1 1 1 Stc1 domain Utp12 PF04003.7 KND92677.1 - 3.6e-20 71.8 0.1 6.9e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 Dip2/Utp12 Family SDA1 PF05285.7 KND92677.1 - 0.7 9.1 28.7 2.7 7.1 0.6 2.1 2 0 0 2 2 2 0 SDA1 Bromodomain PF00439.20 KND92678.1 - 2e-25 88.5 0.0 4.5e-17 61.7 0.0 2.6 2 0 0 2 2 2 2 Bromodomain DUF2763 PF10961.3 KND92678.1 - 1.7 9.0 3.9 4 7.8 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) NUDIX PF00293.23 KND92679.1 - 4.1e-06 26.4 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Beta-lactamase PF00144.19 KND92680.1 - 5.1e-47 160.4 4.9 1.2e-46 159.2 3.4 1.5 1 1 0 1 1 1 1 Beta-lactamase BCDHK_Adom3 PF10436.4 KND92681.1 - 2e-61 206.3 0.0 3.6e-61 205.4 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KND92681.1 - 2.6e-14 52.8 0.0 1e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KND92681.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L22 PF00237.14 KND92681.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e HR1 PF02185.11 KND92682.1 - 0.025 14.2 4.5 0.027 14.2 0.8 2.4 2 0 0 2 2 2 0 Hr1 repeat Atg14 PF10186.4 KND92682.1 - 0.23 10.3 6.4 0.085 11.7 2.1 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KND92682.1 - 2.1 8.1 7.6 1.4 8.7 3.6 2.0 2 0 0 2 2 2 0 Tropomyosin like ATG16 PF08614.6 KND92682.1 - 3.8 7.2 16.1 0.021 14.6 2.9 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) MFS_1 PF07690.11 KND92683.1 - 2.8e-37 128.2 41.6 2.8e-37 128.2 28.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND92683.1 - 1.9e-11 43.2 15.1 1.9e-11 43.2 10.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter AAA_12 PF13087.1 KND92684.1 - 0.033 13.5 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain SBP PF03110.9 KND92685.1 - 0.072 13.3 0.3 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 SBP domain Gon7 PF08738.5 KND92687.1 - 2.2e-13 50.0 0.8 5.7e-12 45.5 0.6 2.0 1 1 0 1 1 1 1 Gon7 family MFS_1 PF07690.11 KND92688.1 - 2e-37 128.7 14.1 1.8e-35 122.3 10.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuclease PF00545.15 KND92689.1 - 1.1e-20 73.4 0.2 1.5e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 ribonuclease Beta-lactamase PF00144.19 KND92691.1 - 2.9e-50 171.1 0.1 4.2e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KND92691.1 - 3.8e-10 39.4 0.0 8.8e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ABC_membrane PF00664.18 KND92692.1 - 3.4e-74 249.7 31.2 3.7e-37 128.2 7.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND92692.1 - 2.5e-60 202.7 0.0 2.6e-30 105.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND92692.1 - 1e-10 41.2 2.0 0.011 15.0 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND92692.1 - 1.9e-10 41.1 0.0 0.2 11.5 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KND92692.1 - 1.4e-09 37.3 0.5 0.0012 18.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KND92692.1 - 9.9e-09 34.2 0.0 0.0015 17.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 KND92692.1 - 1.1e-07 32.0 0.0 0.003 17.6 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND92692.1 - 3.1e-07 30.5 4.4 0.00037 20.5 0.4 3.1 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KND92692.1 - 4.3e-07 29.2 0.0 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KND92692.1 - 1.6e-05 24.7 2.4 0.16 11.9 0.0 4.6 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KND92692.1 - 7.3e-05 23.5 0.0 0.31 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KND92692.1 - 0.00024 20.7 1.1 2.6 7.5 0.0 4.4 5 0 0 5 5 4 1 AAA domain AAA_25 PF13481.1 KND92692.1 - 0.00072 19.0 0.7 0.31 10.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 KND92692.1 - 0.00074 19.8 0.2 0.19 12.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND92692.1 - 0.0018 18.0 0.2 0.48 10.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KND92692.1 - 0.003 17.4 0.1 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND92692.1 - 0.0062 16.8 0.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KND92692.1 - 0.0064 16.3 0.0 1.7 8.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 KND92692.1 - 0.0066 16.4 0.1 0.98 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KND92692.1 - 0.023 14.6 0.1 5.4 7.0 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 KND92692.1 - 0.035 13.9 0.4 8 6.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 KND92692.1 - 0.045 13.4 0.3 7.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KND92692.1 - 0.12 11.0 0.0 7.9 5.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.7 KND92692.1 - 0.12 11.9 0.2 11 5.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain VirE PF05272.6 KND92692.1 - 0.16 11.4 0.0 19 4.6 0.0 2.2 2 0 0 2 2 2 0 Virulence-associated protein E RNA_helicase PF00910.17 KND92692.1 - 0.2 11.8 0.1 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KND92692.1 - 0.47 9.2 0.8 5.1 5.8 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KND92692.1 - 0.95 8.4 0.0 31 3.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AA_permease PF00324.16 KND92693.1 - 8.1e-99 331.1 41.7 9.2e-99 330.9 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND92693.1 - 2.8e-25 88.7 43.2 3.4e-25 88.4 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4050 PF13259.1 KND92694.1 - 1.5e-29 102.3 0.0 6.7e-29 100.2 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) AMP-binding PF00501.23 KND92695.1 - 3.5e-89 299.0 0.1 2.8e-84 282.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KND92695.1 - 2e-52 177.9 0.0 9.8e-34 116.5 0.0 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KND92695.1 - 9.5e-26 89.8 0.1 9.2e-12 45.0 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_29 PF03141.11 KND92695.1 - 0.39 8.9 0.4 0.75 8.0 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pex14_N PF04695.8 KND92697.1 - 9.8e-20 70.9 1.4 1.3e-19 70.6 0.0 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DltD_C PF04914.7 KND92697.1 - 0.04 13.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 DltD C-terminal region PAPA-1 PF04795.7 KND92698.1 - 1.7e-24 86.2 3.8 1.7e-24 86.2 2.7 3.0 2 0 0 2 2 2 1 PAPA-1-like conserved region Ras PF00071.17 KND92699.1 - 1.2e-61 206.8 0.1 1.5e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND92699.1 - 5e-20 72.1 0.0 7.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND92699.1 - 1.2e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND92699.1 - 2.1e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND92699.1 - 0.00019 20.9 0.0 0.00071 19.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KND92699.1 - 0.00027 21.0 0.0 0.00098 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND92699.1 - 0.0023 17.1 0.1 0.0043 16.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 KND92699.1 - 0.0025 16.9 0.0 0.0043 16.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KND92699.1 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KND92699.1 - 0.0042 16.2 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KND92699.1 - 0.0095 15.3 0.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain SpoIIID PF12116.3 KND92699.1 - 0.015 15.2 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_16 PF13191.1 KND92699.1 - 0.016 15.2 0.2 0.036 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KND92699.1 - 0.037 14.3 0.1 0.052 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KND92699.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Chromo PF00385.19 KND92700.1 - 8.7e-09 34.9 0.1 3e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.2 KND92701.1 - 0.003 17.2 0.0 0.011 15.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like PI31_Prot_C PF08577.6 KND92701.1 - 0.0058 17.2 0.3 0.018 15.6 0.0 2.0 2 0 0 2 2 2 1 PI31 proteasome regulator F-box PF00646.28 KND92701.1 - 0.0094 15.5 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain Brix PF04427.13 KND92702.1 - 3.4e-37 127.9 0.0 4.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain NACHT PF05729.7 KND92704.1 - 2.8e-12 46.6 1.9 5.6e-11 42.3 0.1 2.9 2 1 1 3 3 3 1 NACHT domain Ank_2 PF12796.2 KND92704.1 - 2.5e-09 37.3 0.0 5.3e-05 23.4 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) AAA_16 PF13191.1 KND92704.1 - 3.3e-08 33.7 0.1 3.3e-08 33.7 0.1 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KND92704.1 - 1.6e-07 31.5 0.1 2.9e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 KND92704.1 - 1.4e-05 25.4 0.2 0.075 13.5 0.1 5.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND92704.1 - 3.7e-05 23.8 0.2 2.8 8.3 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) KAP_NTPase PF07693.9 KND92704.1 - 0.0042 16.1 0.0 0.014 14.4 0.0 1.8 1 1 1 2 2 2 1 KAP family P-loop domain Ank_3 PF13606.1 KND92704.1 - 0.0051 16.9 0.0 15 6.2 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 KND92704.1 - 0.0055 16.4 2.1 3.5 7.6 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat DUF3293 PF11697.3 KND92704.1 - 0.062 13.4 0.3 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) DUF676 PF05057.9 KND92705.1 - 0.00015 21.0 0.0 0.00031 20.0 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND92705.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Mpv17_PMP22 PF04117.7 KND92707.1 - 2.9e-17 62.0 0.0 5.7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2537 PF10801.3 KND92707.1 - 0.075 13.1 1.0 0.23 11.6 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2537) PgaD PF13994.1 KND92707.1 - 0.12 11.8 0.5 0.61 9.5 0.0 2.2 2 1 0 2 2 2 0 PgaD-like protein SET PF00856.23 KND92708.1 - 6.5e-09 36.2 0.1 5.8e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 SET domain Complex1_LYR PF05347.10 KND92709.1 - 0.00018 21.2 0.2 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND92709.1 - 0.003 17.7 0.2 0.0047 17.1 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 KND92709.1 - 0.016 14.9 1.3 0.02 14.6 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Calc_CGRP_IAPP PF00214.14 KND92709.1 - 0.095 12.7 0.4 0.096 12.7 0.3 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family DnaJ PF00226.26 KND92710.1 - 2.9e-20 71.7 2.5 2.9e-20 71.7 1.7 2.6 2 1 0 2 2 2 1 DnaJ domain Sterol_MT_C PF08498.5 KND92711.1 - 1.1e-28 98.9 0.1 1.7e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KND92711.1 - 3.1e-21 75.6 0.0 5.7e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND92711.1 - 6e-18 64.8 0.0 8.4e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND92711.1 - 2.5e-14 53.4 0.0 4.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND92711.1 - 1.1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND92711.1 - 4.8e-13 48.8 0.0 6.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KND92711.1 - 2.5e-11 43.1 0.0 4.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KND92711.1 - 4.6e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND92711.1 - 3.3e-10 40.3 0.0 7.7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND92711.1 - 2.3e-09 37.3 0.0 6.1e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KND92711.1 - 3.5e-05 23.4 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KND92711.1 - 6.9e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KND92711.1 - 0.00012 21.7 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KND92711.1 - 0.00089 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KND92711.1 - 0.0036 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 KND92711.1 - 0.0069 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KND92711.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 KND92711.1 - 0.037 14.8 0.0 0.12 13.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 KND92711.1 - 0.06 11.6 0.0 0.08 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0020 PF01170.13 KND92711.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 KND92711.1 - 0.16 11.1 0.4 0.35 10.0 0.1 1.7 2 0 0 2 2 2 0 O-methyltransferase RRM_1 PF00076.17 KND92712.1 - 1.2e-09 37.6 0.0 2.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND92712.1 - 1.6e-09 37.5 0.0 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND92712.1 - 8.6e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND92712.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KND92712.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif MFS_1 PF07690.11 KND92713.1 - 1.4e-29 102.9 64.9 5.9e-22 77.8 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1517 PF07466.6 KND92713.1 - 0.062 12.2 0.3 0.16 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3154 PF11351.3 KND92713.1 - 2 8.1 5.1 2.6 7.8 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Transket_pyr PF02779.19 KND92714.1 - 4.9e-62 208.5 0.0 8e-62 207.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KND92714.1 - 3.2e-56 190.2 0.0 4.9e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component WD40 PF00400.27 KND92715.1 - 1e-44 148.8 16.3 3.4e-12 45.7 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KND92715.1 - 0.012 15.1 0.0 42 3.7 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain BSD PF03909.12 KND92716.1 - 3.7e-27 93.8 1.5 2.6e-14 52.6 0.0 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KND92716.1 - 1.1e-24 85.9 0.0 2.7e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Cas_APE2256 PF09651.5 KND92716.1 - 0.12 12.1 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) AAA PF00004.24 KND92717.1 - 3.7e-38 130.7 0.0 9e-38 129.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND92717.1 - 1.8e-06 28.0 0.8 0.0025 17.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND92717.1 - 2e-06 27.8 0.2 0.0049 16.8 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 KND92717.1 - 6.7e-06 25.3 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KND92717.1 - 0.00013 22.7 0.3 0.00091 20.0 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KND92717.1 - 0.00068 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND92717.1 - 0.00093 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND92717.1 - 0.0024 17.5 0.1 0.0057 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KND92717.1 - 0.0033 17.1 0.0 0.026 14.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KND92717.1 - 0.0047 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KND92717.1 - 0.0049 15.6 0.0 0.0083 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KND92717.1 - 0.0067 15.6 0.1 0.017 14.2 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND92717.1 - 0.0077 15.6 0.2 0.2 11.0 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 KND92717.1 - 0.018 14.4 0.3 7.4 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 KND92717.1 - 0.028 14.7 0.1 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KND92717.1 - 0.035 13.2 0.1 0.11 11.6 0.1 1.8 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 KND92717.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KND92717.1 - 0.047 13.2 0.3 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KND92717.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND92717.1 - 0.056 13.7 0.0 0.43 10.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 KND92717.1 - 0.061 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 KND92717.1 - 0.068 12.8 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 KND92717.1 - 0.1 12.4 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 KND92717.1 - 0.2 11.1 0.0 0.46 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KND92717.1 - 0.27 10.0 0.0 0.54 9.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zn_clus PF00172.13 KND92718.1 - 3.7e-07 29.9 10.8 6.6e-07 29.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND92718.1 - 0.00024 19.8 0.1 0.00038 19.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TEX15 PF15326.1 KND92718.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 ATP-synt_ab PF00006.20 KND92719.1 - 5.9e-62 208.9 0.0 9.2e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KND92719.1 - 1e-24 87.1 0.2 1.8e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KND92719.1 - 3.1e-23 81.7 0.4 8.3e-23 80.3 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Arch_ATPase PF01637.13 KND92719.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KND92719.1 - 0.012 14.9 0.4 0.037 13.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KND92719.1 - 0.014 15.0 0.1 1.1 9.0 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KND92719.1 - 0.016 14.3 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 KND92719.1 - 0.023 13.8 0.1 0.037 13.1 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 KND92719.1 - 0.027 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 KND92719.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KND92719.1 - 0.045 13.9 0.0 0.53 10.4 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KND92719.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KND92719.1 - 0.09 12.7 0.2 0.31 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 KND92719.1 - 0.14 11.0 0.3 0.62 8.8 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 KND92720.1 - 4.6e-24 84.3 0.0 1.6e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KND92720.1 - 2.8e-18 66.3 0.2 2.2e-15 56.8 0.2 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 KND92720.1 - 6e-18 64.6 0.0 1.7e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 KND92720.1 - 0.053 12.7 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) ADK_lid PF05191.9 KND92720.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_2 PF07724.9 KND92721.1 - 4.6e-32 111.2 0.0 1.2e-31 109.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KND92721.1 - 5e-12 46.1 0.1 1.1e-11 44.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KND92721.1 - 1.2e-10 41.1 0.0 3.7e-10 39.5 0.0 1.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KND92721.1 - 3e-06 27.0 0.0 7.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND92721.1 - 0.00025 21.1 0.3 0.0018 18.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND92721.1 - 0.00044 21.0 0.6 0.0011 19.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain MCM PF00493.18 KND92721.1 - 0.00051 18.9 0.1 0.0018 17.1 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family AAA_16 PF13191.1 KND92721.1 - 0.00072 19.5 0.0 0.0079 16.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KND92721.1 - 0.00087 19.2 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KND92721.1 - 0.0019 17.6 0.0 0.0051 16.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 KND92721.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 KND92721.1 - 0.085 13.1 0.2 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KND92721.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 KND92721.1 - 0.16 11.7 1.2 0.46 10.2 0.0 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KND92721.1 - 0.2 11.9 0.5 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter COX4 PF02936.9 KND92722.1 - 3.2e-51 172.7 0.0 3.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV OTT_1508_deam PF14441.1 KND92723.1 - 1.3e-23 83.3 0.0 2.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase NADH-u_ox-rdase PF10785.4 KND92724.1 - 6.5e-34 116.0 0.5 1.1e-33 115.3 0.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KND92724.1 - 3.3e-30 103.6 0.0 5e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 KND92725.1 - 4.1e-29 100.0 0.0 8.4e-29 99.0 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 PP1_inhibitor PF05361.7 KND92726.1 - 0.031 13.9 0.0 0.035 13.7 0.0 1.0 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor GMC_oxred_N PF00732.14 KND92727.1 - 7.1e-60 202.6 0.0 1.6e-59 201.5 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND92727.1 - 1.3e-35 122.8 0.0 2.2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KND92727.1 - 0.00027 19.9 0.9 0.00092 18.2 0.6 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KND92727.1 - 0.0076 15.1 5.6 0.51 9.1 2.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KND92727.1 - 0.018 15.0 2.0 0.036 14.1 0.9 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND92727.1 - 0.025 13.5 9.1 0.22 10.3 6.3 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KND92727.1 - 0.23 10.0 1.1 0.35 9.4 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KND92727.1 - 0.41 9.0 1.7 1.1 7.6 0.9 1.8 2 0 0 2 2 2 0 HI0933-like protein Transp_cyt_pur PF02133.10 KND92728.1 - 1.2e-23 83.3 41.7 2.2e-23 82.5 28.9 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF962 PF06127.6 KND92728.1 - 0.0006 19.6 0.0 1.3 8.9 0.0 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF962) DUF427 PF04248.7 KND92731.1 - 1.3e-27 95.2 0.2 1.9e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) NfrA_C PF13283.1 KND92731.1 - 0.12 11.7 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Snf7 PF03357.16 KND92732.1 - 4.9e-06 26.0 25.8 4.9e-06 26.0 17.9 1.6 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 KND92732.1 - 0.021 14.2 6.3 0.034 13.5 4.4 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF3962 PF13111.1 KND92732.1 - 0.12 11.6 0.7 0.17 11.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) ASL_C PF08328.6 KND92732.1 - 0.31 10.8 5.0 0.36 10.6 2.7 1.7 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminal SAGA-Tad1 PF12767.2 KND92732.1 - 0.42 10.2 11.1 0.16 11.5 6.1 1.5 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Dynactin_p62 PF05502.8 KND92732.1 - 1.8 7.2 14.0 2.7 6.6 9.7 1.2 1 0 0 1 1 1 0 Dynactin p62 family DUF1451 PF07295.6 KND92732.1 - 9 6.0 13.2 1.5 8.5 4.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) DUF4246 PF14033.1 KND92733.1 - 1.2e-153 512.3 0.0 1.5e-153 512.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KND92733.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 KND92733.1 - 0.063 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KND92734.1 - 5.1e-21 74.9 0.0 2.2e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND92734.1 - 0.00023 20.3 0.0 0.13 11.2 0.0 2.8 2 2 0 2 2 2 2 Protein tyrosine kinase WaaY PF06176.6 KND92734.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) eIF-3c_N PF05470.7 KND92735.1 - 8e-176 585.6 24.0 8e-176 585.6 16.7 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KND92735.1 - 6.6e-14 52.1 0.0 3.8e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain U1snRNP70_N PF12220.3 KND92735.1 - 8.8 6.7 11.6 3.1 8.1 0.6 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Tannase PF07519.6 KND92736.1 - 2.7e-99 333.0 0.0 3.2e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KND92736.1 - 4.7e-06 26.4 0.2 0.0024 17.6 0.2 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND92736.1 - 0.00011 22.1 1.0 0.00053 19.9 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND92736.1 - 0.0097 15.1 0.1 2 7.5 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KND92736.1 - 0.073 12.6 1.7 0.12 11.9 1.2 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fe-S_biosyn PF01521.15 KND92738.1 - 5.9e-12 45.5 0.0 1.2e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 KND92739.1 - 1.3e-20 73.1 17.1 2.4e-20 72.3 11.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KND92739.1 - 2.2e-18 65.5 2.4 2.3e-18 65.5 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF615 PF04751.9 KND92739.1 - 0.0018 17.9 1.7 0.0028 17.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF615) Endonuc_BglI PF14562.1 KND92739.1 - 0.071 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI Cro PF09048.5 KND92740.1 - 0.048 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Cro SNF2_N PF00176.18 KND92741.1 - 3.7e-71 239.3 0.0 6.8e-71 238.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND92741.1 - 2e-13 49.9 0.0 6e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND92741.1 - 4.1e-05 23.4 0.0 0.00017 21.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND92741.1 - 0.0084 15.6 0.0 0.036 13.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2935 PF11155.3 KND92741.1 - 0.042 13.9 1.4 0.1 12.6 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) APH PF01636.18 KND92743.1 - 0.01 15.5 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos_C PF14008.1 KND92745.1 - 2.5e-19 69.1 0.2 6.3e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 KND92745.1 - 3.2e-17 62.6 1.0 3.1e-16 59.3 0.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 KND92745.1 - 8.2e-07 27.9 0.0 1.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase p450 PF00067.17 KND92746.1 - 5.8e-55 186.6 0.0 7.2e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alkyl_sulf_C PF14864.1 KND92746.1 - 0.068 13.1 0.1 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal E1-E2_ATPase PF00122.15 KND92747.1 - 8.9e-51 172.1 6.2 8.9e-51 172.1 4.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KND92747.1 - 4e-29 102.5 8.8 4e-29 102.5 6.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KND92747.1 - 5.5e-12 45.6 0.0 2.2e-10 40.5 0.0 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.2 KND92747.1 - 2e-11 44.4 0.0 5.1e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YscJ_FliF PF01514.12 KND92747.1 - 0.018 14.2 0.0 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family HyaE PF07449.6 KND92747.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Hydrolase_3 PF08282.7 KND92747.1 - 0.79 9.2 1.7 4.2 6.8 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 KND92748.1 - 2.1e-09 37.1 7.0 1.8e-08 34.1 5.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND92748.1 - 0.019 13.8 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hyd_65N_2 PF14498.1 KND92750.1 - 4e-10 39.7 0.0 9.3e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain dCMP_cyt_deam_1 PF00383.17 KND92751.1 - 5.6e-20 70.9 0.0 1.8e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KND92751.1 - 0.025 14.4 0.1 0.025 14.4 0.0 3.4 3 1 1 4 4 4 0 Bd3614-like deaminase Zn_clus PF00172.13 KND92752.1 - 0.057 13.3 9.1 0.14 12.0 6.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_topoisoIV PF00521.15 KND92753.1 - 2.6e-119 398.8 0.0 6.1e-119 397.6 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KND92753.1 - 2.4e-32 111.5 0.4 5.2e-32 110.4 0.3 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KND92753.1 - 3.8e-13 49.2 0.0 1.2e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KND92753.1 - 8.9e-10 38.2 0.0 2.6e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.2 KND92754.1 - 2.5e-48 162.3 9.8 2.8e-17 62.8 0.0 3.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND92754.1 - 1.1e-30 105.4 3.5 1.2e-10 41.6 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KND92754.1 - 4.7e-25 86.1 0.6 4.3e-06 26.2 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KND92754.1 - 2.7e-22 78.2 2.7 2e-10 40.5 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND92754.1 - 5.6e-18 63.2 1.1 0.00085 19.3 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat F-box-like PF12937.2 KND92754.1 - 0.0009 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like LEA_6 PF10714.4 KND92755.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 dsDNA_bind PF01984.15 KND92756.1 - 2.2e-30 104.7 9.7 6.1e-30 103.3 6.7 1.7 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ApbA_C PF08546.6 KND92756.1 - 1e-13 51.3 0.0 2.7e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KND92756.1 - 1e-09 38.0 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Coq4 PF05019.8 KND92757.1 - 6.2e-92 306.5 0.0 4.9e-86 287.2 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 FAD_binding_3 PF01494.14 KND92758.1 - 3e-11 42.9 0.1 1.9e-09 37.0 0.0 2.9 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 KND92758.1 - 0.00027 19.9 0.7 0.0041 16.0 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND92758.1 - 0.0021 18.0 0.4 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KND92758.1 - 0.016 14.9 6.6 0.22 11.2 0.0 3.9 5 0 0 5 5 5 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KND92758.1 - 0.088 11.7 0.6 0.76 8.6 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein OmpH PF03938.9 KND92759.1 - 2.4 8.0 10.8 13 5.6 6.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rick_17kDa_Anti PF05433.10 KND92760.1 - 6.2 6.5 19.0 2.1 8.0 3.2 2.7 1 1 1 2 2 2 0 Glycine zipper 2TM domain Peptidase_C48 PF02902.14 KND92761.1 - 1.5e-19 70.4 0.0 2.8e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Borrelia_P83 PF05262.6 KND92761.1 - 0.11 10.7 5.3 0.16 10.1 3.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.8 KND92762.1 - 7.9 6.2 30.6 11 5.7 21.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD_binding_3 PF01494.14 KND92763.1 - 7.7e-70 235.7 0.0 1.1e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KND92763.1 - 9.2e-39 132.7 0.0 1.4e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KND92763.1 - 0.083 13.3 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND92763.1 - 0.093 12.7 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.27 KND92765.1 - 7.2e-06 25.6 6.9 0.00038 20.2 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Hira PF07569.6 KND92765.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split LCM PF04072.9 KND92766.1 - 2.3e-20 72.9 0.0 3.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DAO PF01266.19 KND92767.1 - 6.4e-52 176.6 0.0 1e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND92767.1 - 1.8e-08 33.6 2.2 9.3e-08 31.3 1.5 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KND92767.1 - 4.1e-07 29.4 5.4 8.7e-06 25.0 3.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KND92767.1 - 2.2e-05 23.6 1.2 0.038 13.0 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 KND92767.1 - 0.00055 19.0 1.7 0.17 10.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KND92767.1 - 0.00056 19.8 0.2 0.0018 18.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND92767.1 - 0.00062 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND92767.1 - 0.0022 18.3 1.1 0.02 15.2 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND92767.1 - 0.0039 15.7 0.3 0.0066 14.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KND92767.1 - 0.019 13.8 0.2 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KND92767.1 - 0.026 14.1 0.3 0.052 13.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KND92767.1 - 0.029 13.2 0.3 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KND92767.1 - 0.054 13.5 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.14 KND92768.1 - 3.1e-08 33.7 0.0 5.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain HNH_2 PF13391.1 KND92769.1 - 4.6e-10 39.1 0.0 1.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Sigma70_ner PF04546.8 KND92769.1 - 0.026 14.1 1.0 0.038 13.6 0.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Med7 PF05983.6 KND92770.1 - 2.3e-49 167.2 0.0 2.7e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 MED7 protein zf-C2H2_jaz PF12171.3 KND92772.1 - 0.04 14.0 0.4 0.063 13.4 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PAP2 PF01569.16 KND92773.1 - 2.1e-23 82.4 0.3 2.1e-23 82.4 0.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily VanZ PF04892.7 KND92773.1 - 2.6 8.0 9.1 5.6 6.9 1.0 3.6 2 2 1 3 3 3 0 VanZ like family Proteasome PF00227.21 KND92774.1 - 7.2e-45 152.6 0.0 8.3e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KND92775.1 - 1.3e-14 53.1 0.2 1.3e-14 53.1 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Proteasome PF00227.21 KND92775.1 - 1.6e-08 34.0 0.1 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit RPEL PF02755.10 KND92776.1 - 0.045 13.0 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 RPEL repeat ParBc PF02195.13 KND92776.1 - 0.093 12.8 0.4 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 ParB-like nuclease domain zf-AD PF07776.10 KND92777.1 - 2.6 8.0 5.3 4.2 7.4 0.3 2.6 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) GFA PF04828.9 KND92778.1 - 0.0016 18.3 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KND92778.1 - 0.011 14.9 0.2 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KND92778.1 - 0.018 14.4 0.2 0.033 13.6 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KND92778.1 - 0.019 14.4 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.1 KND92778.1 - 0.031 14.5 0.1 0.044 14.0 0.1 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain A2L_zn_ribbon PF08792.5 KND92778.1 - 0.047 13.1 0.3 0.073 12.5 0.2 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-ISL3 PF14690.1 KND92778.1 - 0.11 12.4 0.2 0.18 11.8 0.2 1.4 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MgsA_C PF12002.3 KND92780.1 - 4.7e-61 205.3 0.0 9.6e-61 204.3 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KND92780.1 - 4e-13 49.7 0.1 7.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND92780.1 - 1.8e-10 40.2 0.0 1.1e-09 37.7 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta2 PF13177.1 KND92780.1 - 3e-06 26.9 0.0 0.00072 19.2 0.0 3.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Sigma54_activat PF00158.21 KND92780.1 - 4.2e-05 23.0 0.0 0.0078 15.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KND92780.1 - 4.5e-05 22.6 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KND92780.1 - 0.00013 21.9 0.5 0.033 14.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KND92780.1 - 0.00029 20.5 0.1 0.0041 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KND92780.1 - 0.0011 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND92780.1 - 0.0013 18.9 0.6 0.051 13.7 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KND92780.1 - 0.0025 18.6 0.0 0.0047 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KND92780.1 - 0.0034 16.1 0.0 0.0097 14.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 KND92780.1 - 0.0054 15.6 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SKI PF01202.17 KND92780.1 - 0.0058 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase ResIII PF04851.10 KND92780.1 - 0.0092 15.8 0.1 3.2 7.5 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.6 KND92780.1 - 0.0093 15.5 0.0 0.051 13.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KND92780.1 - 0.038 13.7 0.5 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_2 PF07724.9 KND92780.1 - 0.046 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KND92780.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KND92780.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.6 KND92780.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) PEPCK_ATP PF01293.15 KND92780.1 - 0.24 9.8 0.0 0.38 9.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase tRNA-synt_2b PF00587.20 KND92781.1 - 1.1e-23 83.6 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KND92781.1 - 6.3e-10 39.0 0.6 1.2e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 KND92782.1 - 1e-69 234.5 0.0 2.7e-69 233.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92782.1 - 3.7e-30 104.8 0.0 7.2e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KND92782.1 - 4.3e-05 22.6 0.0 0.43 9.4 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KND92782.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND92782.1 - 0.039 13.6 0.0 1.4 8.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family C2 PF00168.25 KND92783.1 - 1.4e-19 69.7 0.0 1e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain Amidohydro_1 PF01979.15 KND92784.1 - 8.1e-09 35.5 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KND92784.1 - 0.0017 17.6 0.1 0.0036 16.5 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family AA_permease PF00324.16 KND92785.1 - 1.2e-29 103.0 30.4 1.3e-18 66.6 7.8 2.8 2 1 0 2 2 2 2 Amino acid permease DUF4066 PF13278.1 KND92786.1 - 0.0047 16.2 0.0 0.0052 16.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase APH PF01636.18 KND92787.1 - 9.3e-05 22.2 0.0 9.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PALP PF00291.20 KND92789.1 - 5.6e-56 190.0 1.4 9.7e-56 189.2 1.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Alpha-amylase PF00128.19 KND92790.1 - 7.2e-60 203.0 0.0 2.5e-59 201.2 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KND92790.1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.11 KND92790.1 - 0.073 10.8 0.4 3 5.5 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 RhgB_N PF09284.5 KND92791.1 - 0.034 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonase B, N-terminal DUF4646 PF15496.1 KND92793.1 - 0.00028 20.9 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF1814 PF08843.6 KND92794.1 - 0.00016 21.5 0.0 0.00041 20.2 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) CysG_dimeriser PF10414.4 KND92794.1 - 0.0028 17.1 1.2 0.52 9.8 0.0 2.4 2 0 0 2 2 2 2 Sirohaem synthase dimerisation region Lung_7-TM_R PF06814.8 KND92795.1 - 3.3e-72 242.9 16.0 4e-72 242.6 11.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KND92795.1 - 0.043 13.9 14.7 0.46 10.6 0.4 3.2 2 1 1 3 3 3 0 PrgI family protein Pro_isomerase PF00160.16 KND92796.1 - 2.2e-46 157.9 0.0 3.9e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KND92796.1 - 0.00056 19.8 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 U-box domain Pkinase PF00069.20 KND92797.1 - 2.2e-45 154.8 0.0 2.7e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92797.1 - 5e-17 61.8 0.0 7.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND92797.1 - 0.0024 16.8 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND92797.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_28 PF02636.12 KND92798.1 - 5.2e-78 261.9 0.0 6.4e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_16 PF00722.16 KND92800.1 - 4.4e-14 52.1 0.1 6e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 KND92801.1 - 9.8e-09 34.4 2.8 3.4e-06 26.1 1.4 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KND92801.1 - 0.00078 19.6 9.7 0.055 13.7 0.8 2.9 1 1 1 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KND92801.1 - 0.027 14.8 9.4 0.33 11.3 1.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND92801.1 - 0.084 13.2 8.8 1.4 9.4 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.14 KND92801.1 - 0.66 9.6 3.2 0.38 10.4 0.7 1.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Fungal_trans_2 PF11951.3 KND92802.1 - 4.7e-09 35.3 0.1 4.5e-07 28.8 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND92802.1 - 1.4e-07 31.3 11.9 2.5e-07 30.4 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 KND92804.1 - 1.2 7.0 9.7 1.7 6.5 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KND92804.1 - 1.8 6.4 16.3 2.3 6.0 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 KND92804.1 - 5.8 6.6 18.0 7.8 6.2 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RasGEF PF00617.14 KND92806.1 - 1.2e-61 207.7 0.1 2.2e-61 206.8 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KND92806.1 - 4.7e-27 94.1 0.3 1.1e-26 92.8 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KND92806.1 - 6.9e-16 57.3 0.1 1.4e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND92806.1 - 2.2e-14 52.7 0.2 4.5e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND92806.1 - 1.8e-13 49.7 0.1 4.7e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KND92806.1 - 0.034 14.0 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 WW domain PPR_2 PF13041.1 KND92809.1 - 1.4e-21 76.2 0.0 7e-14 51.5 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KND92809.1 - 5.9e-09 35.5 0.8 0.92 9.9 0.0 5.8 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 KND92809.1 - 6.8e-06 25.7 0.9 1.4 9.0 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 KND92809.1 - 0.00013 21.3 0.0 5 6.6 0.1 4.5 4 0 0 4 4 4 1 PPR repeat ATP13 PF12921.2 KND92809.1 - 0.0022 17.3 0.5 0.044 13.1 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ATPase expression HHH_2 PF12826.2 KND92809.1 - 0.13 12.1 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Btz PF09405.5 KND92810.1 - 0.0053 16.7 0.1 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.20 KND92811.1 - 1.8e-52 178.0 0.0 3.9e-52 176.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92811.1 - 3.1e-24 85.4 0.0 6.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND92811.1 - 0.00032 20.5 1.2 0.00053 19.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND92811.1 - 0.0035 16.7 0.1 0.011 15.0 0.1 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KND92811.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Choline_kinase PF01633.15 KND92811.1 - 0.47 9.9 2.6 0.51 9.8 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase AAA_12 PF13087.1 KND92812.1 - 2.4e-28 98.9 0.0 4.2e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND92812.1 - 6.9e-22 78.1 0.0 2.4e-21 76.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND92812.1 - 9.8e-09 34.8 0.1 6.9e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KND92812.1 - 1.8e-05 24.4 0.0 0.0044 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KND92812.1 - 0.00042 20.2 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KND92812.1 - 0.0021 17.5 0.0 0.0066 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KND92812.1 - 0.0045 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND92812.1 - 0.0072 16.4 0.0 0.028 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND92812.1 - 0.0083 16.1 0.1 0.038 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KND92812.1 - 0.01 14.9 0.1 0.034 13.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.24 KND92812.1 - 0.039 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 KND92812.1 - 0.044 13.2 0.1 4.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KND92812.1 - 0.058 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KND92812.1 - 0.061 12.2 0.0 8.1 5.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.17 KND92812.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KND92812.1 - 0.13 11.0 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.16 KND92812.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Parvo_NS1 PF01057.12 KND92812.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIF4G PF02854.14 KND92813.1 - 4.8e-51 173.1 0.0 8.2e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KND92813.1 - 1.9e-19 69.2 2.6 2.3e-19 69.0 0.3 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 HSP70 PF00012.15 KND92813.1 - 0.91 7.3 19.8 2 6.2 13.8 1.5 1 0 0 1 1 1 0 Hsp70 protein DNA_pol_B PF00136.16 KND92814.1 - 4.3e-111 371.9 0.2 6.4e-111 371.4 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KND92814.1 - 1.2e-62 210.5 0.0 2.6e-62 209.5 0.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KND92814.1 - 6.2e-38 130.4 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KND92814.1 - 4.5e-24 84.0 9.4 4.5e-24 84.0 6.5 2.8 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Med2 PF11214.3 KND92816.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Cellulase PF00150.13 KND92817.1 - 5.3e-14 52.0 0.0 9.8e-14 51.2 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S10 PF00338.17 KND92818.1 - 4.8e-23 80.8 0.0 7.2e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF3984 PF13136.1 KND92819.1 - 1.2e-72 244.9 13.2 2e-72 244.1 9.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Lipase_GDSL_2 PF13472.1 KND92820.1 - 6.1e-12 46.0 0.2 9.4e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KND92820.1 - 5.8e-10 39.3 0.1 1.3e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AIP3 PF03915.8 KND92821.1 - 1e-156 522.1 6.5 1.4e-156 521.6 4.5 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1664 PF07889.7 KND92821.1 - 0.0051 16.6 3.6 0.45 10.3 0.0 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) FliL PF03748.9 KND92821.1 - 0.02 14.8 0.1 0.11 12.4 0.1 2.3 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Lectin_N PF03954.9 KND92821.1 - 0.05 12.9 0.2 0.05 12.9 0.1 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 KND92821.1 - 0.073 13.3 6.2 1.2 9.4 0.1 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FH2 PF02181.18 KND92821.1 - 1.5 7.5 6.1 4.2 6.1 0.3 2.7 3 0 0 3 3 3 0 Formin Homology 2 Domain Syntaxin_2 PF14523.1 KND92821.1 - 1.9 8.5 0.0 1.9 8.5 0.0 4.3 5 1 1 6 6 6 0 Syntaxin-like protein IKI3 PF04762.7 KND92822.1 - 0 1023.1 0.0 0 1022.8 0.0 1.0 1 0 0 1 1 1 1 IKI3 family EPSP_synthase PF00275.15 KND92823.1 - 1.1e-129 432.5 0.0 2.4e-129 431.4 0.0 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KND92823.1 - 1.9e-100 335.1 0.0 3.2e-100 334.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KND92823.1 - 6.8e-62 209.0 0.0 2.1e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase RasGAP PF00616.14 KND92823.1 - 2.5e-44 151.3 0.1 6.7e-44 149.9 0.1 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase SKI PF01202.17 KND92823.1 - 9.1e-33 113.3 0.0 2.3e-31 108.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KND92823.1 - 3.8e-24 84.5 0.0 1.1e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KND92823.1 - 9.6e-13 48.3 0.0 3.3e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KND92823.1 - 5.9e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase CRAL_TRIO_2 PF13716.1 KND92823.1 - 6.9e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain AAA_17 PF13207.1 KND92823.1 - 0.00023 21.9 0.0 0.00073 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND92823.1 - 0.035 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.21 KND92824.1 - 1.3e-06 28.3 23.5 0.0072 16.6 1.2 4.2 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND92824.1 - 0.0004 20.5 27.1 0.003 17.7 1.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger ARD PF03079.9 KND92825.1 - 7.2e-44 149.4 0.0 9e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KND92825.1 - 8.6e-08 31.5 0.2 1.4e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KND92825.1 - 1.2e-05 25.0 0.1 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KND92825.1 - 0.035 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 KND92826.1 - 4.9e-19 68.8 0.0 7.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND92826.1 - 2.3e-11 43.7 0.0 4.4e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND92826.1 - 1.8e-06 27.6 0.0 3.1e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND92826.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND92826.1 - 0.0046 15.6 0.0 0.0068 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KND92826.1 - 0.0099 14.7 0.0 0.019 13.8 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 KND92826.1 - 0.097 11.9 0.1 0.22 10.7 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family DER1 PF04511.10 KND92827.1 - 3.8e-49 166.8 4.7 4.4e-49 166.6 3.3 1.0 1 0 0 1 1 1 1 Der1-like family PHO4 PF01384.15 KND92828.1 - 6.7e-98 327.3 20.2 8.5e-98 326.9 14.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family Syndecan PF01034.15 KND92828.1 - 0.65 9.6 5.9 1 9.0 0.0 3.4 3 0 0 3 3 3 0 Syndecan domain FUN14 PF04930.10 KND92829.1 - 0.0027 17.9 2.5 0.0027 17.9 1.7 2.1 2 0 0 2 2 2 1 FUN14 family tRNA-synt_1b PF00579.20 KND92831.1 - 4.4e-73 245.9 0.0 5.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_M24 PF00557.19 KND92832.1 - 7.1e-42 143.3 0.0 1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KND92832.1 - 1e-19 71.3 0.0 3.6e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain PAD_porph PF04371.10 KND92833.1 - 1.4e-82 277.3 0.0 1.6e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 KND92833.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.7 1 1 0 1 1 1 0 Amidinotransferase Fungal_trans PF04082.13 KND92834.1 - 8.1e-15 54.3 0.4 1.2e-14 53.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_2 PF02230.11 KND92835.1 - 1.3e-24 86.9 0.0 3.1e-17 62.7 0.0 2.3 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KND92835.1 - 0.00028 20.6 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND92835.1 - 0.0006 19.7 0.1 0.00096 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KND92835.1 - 0.003 16.8 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KND92835.1 - 0.0083 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Strep_67kDa_ant PF06100.6 KND92836.1 - 2.1e-236 785.0 0.0 2.5e-236 784.8 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KND92836.1 - 3.6e-07 30.0 0.1 9e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND92836.1 - 0.0012 19.1 0.1 0.56 10.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND92836.1 - 0.0045 15.9 0.1 0.094 11.6 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND92836.1 - 0.016 15.3 0.4 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND92836.1 - 0.036 12.9 0.3 0.14 10.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KND92836.1 - 0.087 11.8 0.0 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_7 PF03441.9 KND92837.1 - 1.9e-55 188.0 0.3 2.7e-55 187.5 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KND92837.1 - 9.7e-21 74.2 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Cupredoxin_1 PF13473.1 KND92838.1 - 0.003 17.4 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain Cu_bind_like PF02298.12 KND92838.1 - 0.0091 15.7 0.3 0.027 14.2 0.2 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 KND92838.1 - 0.015 15.4 0.5 0.11 12.7 0.3 2.2 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family MmgE_PrpD PF03972.9 KND92839.1 - 2.6e-142 474.1 0.0 2.9e-142 473.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF663 PF04950.7 KND92841.1 - 2.9e-102 341.6 0.0 4.5e-102 341.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KND92841.1 - 4e-18 64.7 0.0 9.2e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Asp PF00026.18 KND92842.1 - 2.6e-71 240.4 6.1 3.4e-71 240.0 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND92842.1 - 2.7e-10 40.4 1.2 2.7e-10 40.4 0.8 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND92842.1 - 2.4e-05 24.7 0.1 0.0017 18.7 0.0 3.0 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KND92842.1 - 0.011 15.3 0.0 0.05 13.1 0.0 2.1 2 1 1 3 3 3 0 Xylanase inhibitor C-terminal CLU PF13236.1 KND92843.1 - 2.2e-79 265.9 0.0 3.4e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KND92843.1 - 9.1e-54 181.9 0.0 5.2e-53 179.4 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KND92843.1 - 2.6e-23 81.9 0.0 4.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KND92843.1 - 3.3e-18 65.3 9.5 6.2e-08 32.4 0.6 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KND92843.1 - 4.5e-13 48.6 0.0 0.0014 18.4 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KND92843.1 - 1.5e-05 24.5 3.6 0.024 14.2 0.2 3.3 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KND92843.1 - 0.00061 19.5 1.8 0.055 13.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND92843.1 - 0.021 14.6 2.4 0.11 12.2 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KND92843.1 - 0.072 13.3 1.7 17 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat BRF1 PF07741.8 KND92843.1 - 0.22 11.7 4.7 0.32 11.2 0.1 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TctB PF07331.6 KND92844.1 - 0.025 14.2 0.4 0.094 12.3 0.1 1.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Nuc_sug_transp PF04142.10 KND92845.1 - 1.7e-08 33.8 0.2 1.7e-08 33.8 0.2 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KND92845.1 - 1.4e-07 31.5 22.9 4.2e-05 23.6 2.6 2.9 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KND92845.1 - 7e-07 28.4 7.7 1.1e-06 27.7 5.3 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KND92845.1 - 0.025 14.2 19.7 0.067 12.8 0.2 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF3353 PF11833.3 KND92845.1 - 0.071 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF2985 PF11204.3 KND92846.1 - 1.7e-39 133.4 1.4 1.7e-39 133.4 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF1469 PF07332.6 KND92846.1 - 0.26 10.9 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) ADH_N PF08240.7 KND92847.1 - 1.4e-30 105.2 2.9 1.4e-30 105.2 1.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND92847.1 - 1.7e-18 66.4 0.0 2.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND92847.1 - 0.006 17.4 0.0 0.01 16.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AP_endonuc_2 PF01261.19 KND92847.1 - 0.0076 15.5 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel ADH_N_assoc PF13823.1 KND92847.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 KND92847.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 KND92847.1 - 0.063 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sen15 PF09631.5 KND92848.1 - 1.4e-29 102.2 0.0 1.7e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Peptidase_C2 PF00648.16 KND92850.1 - 7.1e-17 61.3 0.0 1.8e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KND92850.1 - 3.5e-15 55.9 0.0 4.8e-13 48.9 0.0 2.8 2 2 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 KND92850.1 - 0.015 15.1 2.1 0.025 14.4 1.4 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-C2H2_4 PF13894.1 KND92852.1 - 0.0014 18.8 6.4 1.2 9.5 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KND92852.1 - 0.0037 17.5 6.9 2.2 8.7 0.1 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND92852.1 - 0.048 13.9 3.4 1.6 9.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF3275 PF11679.3 KND92852.1 - 1.7 8.2 3.4 3.9 7.0 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) GHMP_kinases_N PF00288.21 KND92853.1 - 8.6e-19 67.3 0.1 2.8e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND92853.1 - 4e-10 39.7 0.0 1.2e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KND92853.1 - 0.0098 15.1 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature IncA PF04156.9 KND92853.1 - 0.16 11.5 0.3 0.37 10.3 0.2 1.4 1 1 0 1 1 1 0 IncA protein 2OG-FeII_Oxy_3 PF13640.1 KND92854.1 - 1.2e-10 41.8 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KND92854.1 - 1.8e-05 24.2 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PNP_UDP_1 PF01048.15 KND92855.1 - 1.3e-10 40.6 0.0 1.4e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.6 KND92855.1 - 0.028 13.2 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) cobW PF02492.14 KND92856.1 - 2.3e-32 111.8 0.0 4.6e-32 110.8 0.0 1.5 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KND92856.1 - 4.7e-05 22.3 0.1 0.06 12.1 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 KND92856.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KND92856.1 - 0.054 12.8 0.5 0.086 12.2 0.4 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KND92856.1 - 0.071 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 KND92856.1 - 0.1 12.0 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.1 KND92856.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Nop25 PF09805.4 KND92857.1 - 6.2 6.9 16.7 2.3 8.2 4.2 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BING4CT PF08149.6 KND92858.1 - 1.1e-40 137.0 0.1 4.6e-38 128.5 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 KND92858.1 - 3.7e-09 36.1 0.0 0.00012 21.7 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KND92858.1 - 5.1e-06 25.5 0.1 0.0006 18.7 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 KND92858.1 - 0.071 11.3 0.0 8.1 4.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ras PF00071.17 KND92859.1 - 1.2e-55 187.2 0.0 1.4e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND92859.1 - 1.8e-15 57.4 0.0 2.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND92859.1 - 3e-07 29.8 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND92859.1 - 0.0021 17.2 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KND92859.1 - 0.023 13.8 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Aa_trans PF01490.13 KND92860.1 - 1.7e-67 227.6 30.6 2.1e-67 227.3 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PPTA PF01239.17 KND92861.1 - 0.00035 19.8 13.7 0.037 13.3 0.4 4.4 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat Spc7 PF08317.6 KND92862.1 - 0.006 15.2 4.8 0.0097 14.5 3.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF722 PF05263.6 KND92862.1 - 0.0066 16.5 1.7 0.0096 16.0 0.2 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF722) Atg14 PF10186.4 KND92862.1 - 0.01 14.7 4.2 0.017 14.0 2.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec2p PF06428.6 KND92862.1 - 0.042 13.6 2.9 0.062 13.1 0.1 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p IncA PF04156.9 KND92862.1 - 0.12 11.9 11.7 0.9 9.1 7.9 2.1 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 KND92862.1 - 0.13 12.0 4.6 1.6 8.5 0.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FTO_CTD PF12934.2 KND92862.1 - 0.45 10.0 5.1 1.3 8.6 3.6 1.7 1 0 0 1 1 1 0 FTO C-terminal domain GAS PF13851.1 KND92862.1 - 0.82 8.8 8.4 1.4 8.0 5.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RBD-FIP PF09457.5 KND92862.1 - 0.87 9.4 3.7 7.7 6.4 0.1 3.0 2 0 0 2 2 2 0 FIP domain V_ATPase_I PF01496.14 KND92862.1 - 1 7.0 3.5 3.2 5.4 2.4 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 KND92862.1 - 1.6 8.1 4.8 11 5.3 3.3 2.1 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like SR-25 PF10500.4 KND92862.1 - 3.8 6.9 23.9 1.9 7.9 3.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 KND92862.1 - 9.4 4.3 16.0 0.57 8.4 7.3 1.6 2 0 0 2 2 2 0 Transmembrane protein Vfa1 PF08432.5 KND92862.1 - 9.9 6.1 12.8 14 5.7 8.5 1.5 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AKAP7_NLS PF10469.4 KND92863.1 - 2.7e-28 99.1 0.0 3.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KND92863.1 - 0.035 13.8 0.0 0.16 11.6 0.0 1.9 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily Ras PF00071.17 KND92864.1 - 5.9e-52 175.3 0.0 7.1e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND92864.1 - 7.3e-16 58.7 0.0 1.2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND92864.1 - 6.8e-06 25.4 0.0 9.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 KND92865.1 - 4.2e-85 285.4 0.2 7.4e-84 281.3 0.0 2.6 3 0 0 3 3 3 1 Arginase family tRNA-synt_2 PF00152.15 KND92865.1 - 2.5e-63 213.9 0.0 3.6e-62 210.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND92865.1 - 4.9e-08 32.7 0.0 8.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 KND92865.1 - 0.04 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MFS_1 PF07690.11 KND92866.1 - 5e-47 160.3 32.6 1.7e-39 135.5 12.6 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 KND92866.1 - 1e-07 30.5 12.8 0.00011 20.4 4.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.19 KND92866.1 - 0.0001 21.0 20.9 0.0017 17.0 3.9 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KND92866.1 - 0.00061 18.2 27.6 0.0011 17.5 6.4 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein SURF1 PF02104.10 KND92867.1 - 1.2e-64 218.0 0.0 1.5e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 KND92868.1 - 3e-89 300.1 23.0 3e-89 300.1 15.9 2.4 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T DUF2378 PF09536.5 KND92868.1 - 0.042 13.3 0.0 0.33 10.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2378) DUF2392 PF10288.4 KND92870.1 - 4.7e-18 65.4 0.0 1.9e-16 60.3 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 KND92870.1 - 0.013 14.9 0.0 0.062 12.8 0.0 2.1 1 1 0 1 1 1 0 PP-loop family SchA_CurD PF04486.7 KND92870.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 SchA/CurD like domain Musclin PF11037.3 KND92870.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle DZR PF12773.2 KND92870.1 - 0.12 12.2 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon Ras PF00071.17 KND92871.1 - 2.4e-49 166.8 0.0 1.2e-33 115.8 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KND92871.1 - 6.3e-15 55.7 0.0 2.7e-10 40.7 0.0 2.2 1 1 1 2 2 2 2 Miro-like protein Arf PF00025.16 KND92871.1 - 7.2e-06 25.3 0.0 0.0009 18.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family RRM_1 PF00076.17 KND92872.1 - 3.8e-09 36.0 0.2 1e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND92872.1 - 5.3e-08 32.7 0.0 1.7e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND92872.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reticulon PF02453.12 KND92873.1 - 9.6e-34 116.4 4.1 1.6e-33 115.7 2.0 2.0 3 0 0 3 3 3 1 Reticulon TAP42 PF04177.7 KND92874.1 - 3.9e-87 292.3 0.0 4.4e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Pkinase PF00069.20 KND92875.1 - 1.1e-13 50.9 0.0 7.9e-13 48.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KND92875.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND92875.1 - 0.0055 15.8 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND92875.1 - 0.022 13.7 0.2 1.5 7.7 0.0 2.8 2 1 0 3 3 3 0 Kinase-like Pkinase_Tyr PF07714.12 KND92875.1 - 0.034 13.1 0.0 0.3 10.1 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Ion_trans PF00520.26 KND92876.1 - 4.1e-05 22.9 23.5 0.0011 18.2 16.3 2.4 1 1 0 1 1 1 1 Ion transport protein RabGAP-TBC PF00566.13 KND92877.1 - 5.8e-43 146.8 0.0 1.2e-42 145.8 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prominin PF05478.6 KND92877.1 - 0.15 9.5 1.7 0.27 8.7 1.2 1.4 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 KND92877.1 - 0.21 11.3 2.5 0.65 9.7 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KND92877.1 - 0.26 11.6 0.1 0.26 11.6 0.1 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF972) IncA PF04156.9 KND92877.1 - 0.31 10.5 21.0 0.27 10.7 5.5 3.4 3 0 0 3 3 3 0 IncA protein Fib_alpha PF08702.5 KND92877.1 - 0.51 10.4 13.1 0.026 14.6 3.2 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Utp12 PF04003.7 KND92877.1 - 3.6 7.5 8.4 0.92 9.4 0.7 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family DNA_topoisoIV PF00521.15 KND92878.1 - 9.8e-119 396.9 0.0 2.9e-118 395.4 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KND92878.1 - 1.4e-33 115.4 0.4 3.3e-33 114.3 0.3 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KND92878.1 - 6e-13 48.6 0.0 2.2e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KND92878.1 - 1.7e-09 37.3 0.1 5.5e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.24 KND92880.1 - 6.3e-41 139.6 0.3 9.3e-41 139.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND92880.1 - 1.6e-21 75.9 0.3 5e-21 74.3 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND92880.1 - 0.043 13.6 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF663 PF04950.7 KND92881.1 - 1.1e-89 300.3 0.0 1.1e-89 300.3 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KND92881.1 - 1.6e-26 91.6 0.0 4.9e-25 86.8 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KND92881.1 - 1.2e-05 24.8 0.0 0.0017 17.8 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KND92881.1 - 1.8e-05 24.7 0.0 7.8e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND92881.1 - 4.3e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KND92881.1 - 0.00019 21.3 0.0 0.00052 19.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KND92881.1 - 0.00022 21.5 0.2 0.0012 19.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 KND92881.1 - 0.00024 20.7 0.0 0.00059 19.5 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KND92881.1 - 0.00049 19.8 0.1 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Miro PF08477.8 KND92881.1 - 0.00055 20.4 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA PF00004.24 KND92881.1 - 0.00062 19.9 0.2 0.002 18.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KND92881.1 - 0.0011 18.4 0.1 0.0068 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KND92881.1 - 0.0015 18.0 0.0 0.0058 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND92881.1 - 0.0017 18.2 0.3 0.0052 16.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 KND92881.1 - 0.0024 17.6 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KND92881.1 - 0.0037 16.7 0.0 0.014 14.9 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KND92881.1 - 0.0043 17.8 0.0 0.0043 17.8 0.0 4.1 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 KND92881.1 - 0.0044 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KND92881.1 - 0.0059 16.3 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.17 KND92881.1 - 0.0068 16.5 0.1 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 KND92881.1 - 0.015 14.8 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KND92881.1 - 0.017 14.0 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 KND92881.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KND92881.1 - 0.026 13.7 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KND92881.1 - 0.034 14.1 0.0 0.034 14.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 KND92881.1 - 0.056 13.7 0.0 0.056 13.7 0.0 4.3 5 0 0 5 5 3 0 AAA domain AAA_21 PF13304.1 KND92881.1 - 0.26 11.2 1.5 0.87 9.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KND92881.1 - 0.45 10.8 0.0 0.45 10.8 0.0 4.0 3 1 0 3 3 2 0 AAA domain 2OG-FeII_Oxy_2 PF13532.1 KND92882.1 - 6.2e-32 111.0 0.0 8.4e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KND92882.1 - 7.7e-10 38.5 4.3 1.5e-09 37.5 3.0 1.5 1 0 0 1 1 1 1 GRF zinc finger PfkB PF00294.19 KND92883.1 - 2.5e-55 187.7 0.2 3e-55 187.4 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CHAT PF12770.2 KND92883.1 - 0.047 12.8 1.3 0.47 9.5 0.1 2.1 1 1 0 2 2 2 0 CHAT domain SUR7 PF06687.7 KND92884.1 - 1.5e-29 103.1 0.0 1.7e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KND92884.1 - 0.0002 21.3 2.1 0.0002 21.3 1.4 2.3 3 0 0 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 KND92884.1 - 0.4 10.3 7.4 0.82 9.3 1.6 2.8 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ras PF00071.17 KND92885.1 - 1.3e-40 138.4 0.0 7.6e-40 135.9 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KND92885.1 - 1.5e-17 64.2 0.0 2.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND92885.1 - 4.1e-10 39.1 0.0 6.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND92885.1 - 0.0053 16.6 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KND92885.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KND92885.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KND92885.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KND92885.1 - 0.058 13.1 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KND92885.1 - 0.093 12.6 0.2 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KND92885.1 - 0.11 12.1 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2411 PF10304.4 KND92885.1 - 0.12 11.9 0.2 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) PduV-EutP PF10662.4 KND92885.1 - 0.15 11.5 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0560 PF10577.4 KND92886.1 - 0.019 13.2 0.0 0.02 13.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 HA2 PF04408.18 KND92887.1 - 8.2e-27 93.2 0.4 8.2e-27 93.2 0.3 2.2 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KND92887.1 - 3.3e-25 88.1 0.0 9.9e-25 86.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KND92887.1 - 2.6e-12 46.4 0.0 6.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KND92887.1 - 6.2e-09 35.8 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KND92887.1 - 1.2e-05 24.8 0.2 5.4e-05 22.7 0.4 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND92887.1 - 3.9e-05 23.8 0.1 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KND92887.1 - 4.7e-05 22.4 0.1 0.00016 20.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 KND92887.1 - 0.00038 20.1 0.2 0.019 14.6 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KND92887.1 - 0.014 15.2 0.1 0.11 12.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KND92887.1 - 0.023 13.9 0.1 0.085 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 KND92887.1 - 0.076 13.3 0.3 0.34 11.1 0.2 2.1 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.4 KND92887.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Myosin_head PF00063.16 KND92887.1 - 0.09 10.7 0.0 0.14 10.1 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Sigma54_activ_2 PF14532.1 KND92887.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 KND92888.1 - 1.8e-51 173.7 0.1 2.2e-38 131.4 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND92888.1 - 1.7e-07 30.5 0.0 8.6e-05 21.6 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND92888.1 - 8.1e-06 25.9 0.0 0.31 11.0 0.0 3.6 2 2 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 KND92888.1 - 1.6e-05 24.3 0.2 0.9 8.9 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_5 PF07728.9 KND92888.1 - 3e-05 23.7 0.1 0.12 12.1 0.0 3.7 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND92888.1 - 6.8e-05 23.0 0.0 0.78 9.8 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 KND92888.1 - 0.00017 21.2 4.3 0.023 14.4 0.0 4.0 3 1 0 3 3 3 1 Part of AAA domain AAA_28 PF13521.1 KND92888.1 - 0.0016 18.4 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KND92888.1 - 0.005 16.0 1.3 1.4 8.0 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KND92888.1 - 0.0074 15.7 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 KND92888.1 - 0.014 15.5 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.9 KND92888.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KND92888.1 - 0.03 14.2 0.0 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.5 KND92888.1 - 0.07 13.0 0.1 4.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.13 KND92888.1 - 0.086 12.3 0.0 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KND92888.1 - 0.11 12.3 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KND92888.1 - 0.2 10.6 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 KND92888.1 - 0.21 10.2 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Glyco_hydro_61 PF03443.9 KND92889.1 - 4.8e-45 154.0 0.0 6.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 KND92890.1 - 2.8e-60 203.6 0.1 7.4e-60 202.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92890.1 - 2e-21 76.2 0.0 4.4e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND92890.1 - 0.0076 16.0 0.1 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND92890.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.5 KND92891.1 - 0.19 11.0 0.9 0.36 10.1 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4337 PF14235.1 KND92891.1 - 0.2 11.4 0.2 0.3 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pyr_redox_2 PF07992.9 KND92892.1 - 1.4e-16 60.9 0.1 2.2e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND92892.1 - 0.00022 21.5 0.9 0.00022 21.5 0.6 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND92892.1 - 0.00025 20.0 0.0 0.002 17.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KND92892.1 - 0.0046 15.9 0.3 0.032 13.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KND92892.1 - 0.005 16.9 0.3 0.091 12.8 0.1 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND92892.1 - 0.089 12.5 0.8 2.9 7.6 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thioesterase PF00975.15 KND92893.1 - 1.7e-09 38.2 0.1 1.6e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KND92893.1 - 0.0048 16.8 0.3 0.0069 16.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND92893.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KND92893.1 - 0.06 12.9 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KND92893.1 - 0.14 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TPR_12 PF13424.1 KND92895.1 - 3.7e-06 26.7 0.5 0.016 15.0 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KND92895.1 - 8.2e-06 25.7 1.7 0.014 15.7 0.6 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND92895.1 - 0.0003 21.1 0.5 0.54 11.0 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND92895.1 - 0.0019 18.0 0.0 2.9 8.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND92895.1 - 0.0033 17.7 0.5 0.16 12.3 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND92895.1 - 0.0082 16.7 0.5 0.4 11.4 0.2 3.2 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KND92895.1 - 0.0098 15.8 0.2 0.25 11.3 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Reo_sigmaC PF04582.7 KND92895.1 - 0.045 12.9 1.6 0.3 10.2 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Apc3 PF12895.2 KND92895.1 - 0.057 13.5 0.0 0.35 11.0 0.0 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Dimer_Tnp_Tn5 PF02281.11 KND92895.1 - 0.12 12.5 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain TPR_1 PF00515.23 KND92895.1 - 0.16 11.6 0.0 8.2 6.2 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Xan_ur_permease PF00860.15 KND92896.1 - 9.9e-05 20.9 0.5 0.00013 20.6 0.4 1.1 1 0 0 1 1 1 1 Permease family Glyco_tranf_2_3 PF13641.1 KND92898.1 - 1.3e-06 28.3 0.1 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HNH_2 PF13391.1 KND92899.1 - 4.5e-11 42.3 0.2 9.9e-11 41.2 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Acetyltransf_7 PF13508.1 KND92900.1 - 2.9e-09 36.9 0.0 5.6e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND92900.1 - 3.9e-07 29.9 0.0 8e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KND92900.1 - 3.2e-06 27.0 0.0 6.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND92900.1 - 3.8e-06 26.5 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KND92900.1 - 5.9e-06 26.3 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_tranf_2_3 PF13641.1 KND92901.1 - 0.0032 17.2 0.1 0.0042 16.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ank PF00023.25 KND92903.1 - 6.6e-51 167.6 1.5 9.1e-08 31.5 0.0 7.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 KND92903.1 - 8.6e-47 157.4 1.2 1.4e-15 57.4 0.0 4.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND92903.1 - 8e-35 118.6 3.7 3.2e-11 43.4 0.0 6.0 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND92903.1 - 4.5e-34 115.7 2.1 6.2e-11 42.1 0.1 5.9 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND92903.1 - 4.7e-30 100.6 0.8 0.00021 21.2 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat HET PF06985.6 KND92903.1 - 2.5e-09 37.4 4.6 1.1e-07 32.1 0.2 2.9 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.2 KND92904.1 - 2.1e-24 85.5 1.2 2.6e-23 82.0 0.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KND92904.1 - 0.0013 18.8 0.1 0.0038 17.3 0.1 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND92904.1 - 0.015 15.3 0.2 0.12 12.5 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.2 KND92905.1 - 6.3e-70 231.5 11.4 1.2e-14 54.4 1.0 8.0 1 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KND92905.1 - 3.4e-43 143.3 25.4 1.1e-05 24.9 0.0 13.4 12 2 1 13 13 13 7 Ankyrin repeat Ank_3 PF13606.1 KND92905.1 - 5e-40 131.5 17.3 0.00023 21.0 0.0 13.5 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.1 KND92905.1 - 3.7e-39 132.4 15.4 7.9e-07 29.4 0.0 10.2 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND92905.1 - 2.7e-34 116.4 17.0 2.7e-07 30.6 0.1 10.4 5 2 6 11 11 11 8 Ankyrin repeats (many copies) ADH_N PF08240.7 KND92906.1 - 2.4e-26 91.6 4.4 4.9e-26 90.6 3.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND92906.1 - 3.2e-16 59.0 0.1 1e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase WD40 PF00400.27 KND92906.1 - 7.9e-05 22.3 4.6 0.0019 18.0 0.0 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat 2-Hacid_dh_C PF02826.14 KND92906.1 - 0.00059 19.0 0.6 0.001 18.2 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KND92907.1 - 5.2e-43 143.4 22.4 1.3e-09 37.5 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KND92907.1 - 3.4e-10 39.4 0.3 9.3e-10 38.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KND92907.1 - 3.6e-06 25.4 4.0 0.058 11.5 0.0 4.0 1 1 3 5 5 5 2 Nucleoporin Nup120/160 F-box PF00646.28 KND92907.1 - 4.1e-06 26.3 0.0 8.4e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cytochrom_D1 PF02239.11 KND92907.1 - 0.0016 16.8 0.1 0.0039 15.5 0.0 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KND92907.1 - 0.0037 16.0 0.1 0.43 9.2 0.0 2.5 2 1 0 2 2 2 2 Nup133 N terminal like FlaG PF03646.10 KND92907.1 - 0.04 14.0 0.0 5.3 7.2 0.0 3.1 3 0 0 3 3 3 0 FlaG protein Metallophos_2 PF12850.2 KND92908.1 - 1e-07 31.9 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND92908.1 - 3.7e-05 23.2 3.5 0.00034 20.0 2.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_10 PF13374.1 KND92910.1 - 2.2e-23 81.4 0.1 1.6e-09 37.4 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND92910.1 - 5.2e-19 67.9 0.0 3.3e-13 49.3 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND92910.1 - 8.1e-08 31.5 0.2 0.12 12.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND92910.1 - 0.0021 17.8 0.0 13 6.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND92910.1 - 0.019 15.6 0.0 0.78 10.4 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 KND92910.1 - 0.029 14.3 0.1 0.27 11.2 0.0 2.0 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_4 PF07721.9 KND92910.1 - 0.042 14.2 0.0 11 6.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND92910.1 - 0.054 13.1 0.0 29 4.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KND92910.1 - 0.095 12.9 0.0 66 4.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KND92911.1 - 1.1e-09 37.7 0.0 2.2e-09 36.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND92911.1 - 3e-05 23.2 0.0 4.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND92911.1 - 0.00011 21.3 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND92911.1 - 0.0019 17.9 0.7 0.0043 16.8 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND92911.1 - 0.0027 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pectate_lyase_3 PF12708.2 KND92912.1 - 7.2e-82 274.8 28.6 9.4e-69 231.9 9.8 3.1 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KND92912.1 - 4.7e-05 22.7 2.6 0.11 12.0 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Thiolase_N PF00108.18 KND92914.1 - 3.3e-90 301.6 1.8 4.8e-90 301.1 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND92914.1 - 2e-38 130.5 1.3 2e-38 130.5 0.9 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KND92914.1 - 0.00024 20.6 1.3 0.00046 19.7 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KND92914.1 - 2.8 7.6 6.5 4.1 7.1 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 KND92915.1 - 1.7e-51 173.3 0.1 2.3e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND92915.1 - 3.1e-06 26.9 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND92915.1 - 0.0076 16.1 0.1 0.012 15.4 0.1 1.6 1 1 0 1 1 1 1 RWD domain SUN PF03856.8 KND92916.1 - 4.9e-72 242.2 15.1 7.8e-72 241.5 10.5 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) PCI PF01399.22 KND92917.1 - 0.0073 16.6 0.0 0.069 13.4 0.0 2.1 2 0 0 2 2 2 1 PCI domain LCM PF04072.9 KND92918.1 - 3.7e-22 78.7 0.0 5.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.11 KND92919.1 - 1.2e-28 98.7 2.4 3.5e-28 97.2 0.2 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Kinesin PF00225.18 KND92920.1 - 1.5e-113 378.9 0.4 1.5e-113 378.9 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain ERM PF00769.14 KND92920.1 - 1.1 8.6 61.2 0.062 12.8 14.7 3.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Mito_carr PF00153.22 KND92921.1 - 0.099 12.3 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial carrier protein DUF2422 PF10337.4 KND92922.1 - 1.3e-11 43.9 9.0 1.4e-07 30.7 0.0 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 KND92922.1 - 1.1e-08 34.1 10.1 2.3e-07 29.8 5.7 2.5 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 KND92922.1 - 6e-08 32.6 21.6 6e-08 32.6 15.0 3.2 2 1 1 3 3 3 2 Fusaric acid resistance protein-like Clat_adaptor_s PF01217.15 KND92923.1 - 2.9e-56 189.1 1.8 3.3e-56 188.9 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCI_Csn8 PF10075.4 KND92924.1 - 1.4e-35 122.1 0.0 2.1e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KND92924.1 - 3.4e-22 79.0 0.2 4.8e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3453 PF11935.3 KND92924.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3453) DNA_ligase_A_M PF01068.16 KND92925.1 - 9.1e-48 162.2 0.0 2.9e-45 154.1 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KND92925.1 - 4.8e-41 140.5 0.0 8.4e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KND92925.1 - 4.6e-18 65.4 0.0 3.1e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Sugar_tr PF00083.19 KND92926.1 - 2.8e-64 217.3 18.3 3.8e-64 216.9 12.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND92926.1 - 3.1e-10 39.2 62.4 1.6e-07 30.3 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4191 PF13829.1 KND92926.1 - 1.7 7.7 4.0 2.5 7.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Cellulase PF00150.13 KND92927.1 - 4.5e-12 45.7 1.4 1.1e-08 34.6 0.3 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KND92927.1 - 0.005 16.2 0.1 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KND92927.1 - 0.017 14.2 0.1 3.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase DUF1767 PF08585.7 KND92928.1 - 0.00024 21.3 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 KND92929.1 - 2.2e-45 152.1 35.4 2.9e-08 33.2 0.0 12.4 8 3 2 12 12 12 9 TPR repeat TPR_16 PF13432.1 KND92929.1 - 1.3e-35 121.2 44.6 3.5e-08 33.9 2.2 13.0 11 2 2 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 KND92929.1 - 2e-28 95.9 43.3 0.036 13.9 0.0 16.6 18 0 0 18 18 16 9 Tetratricopeptide repeat TPR_14 PF13428.1 KND92929.1 - 2.5e-27 92.8 34.5 0.042 14.4 0.2 16.0 13 4 4 17 17 16 9 Tetratricopeptide repeat TPR_1 PF00515.23 KND92929.1 - 3e-25 86.7 23.2 0.0015 18.0 0.0 13.7 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_17 PF13431.1 KND92929.1 - 3.1e-23 79.9 24.3 0.15 12.3 0.0 15.5 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND92929.1 - 3.4e-23 81.3 42.9 8e-05 22.5 0.0 13.2 9 5 4 14 14 13 8 Tetratricopeptide repeat TPR_19 PF14559.1 KND92929.1 - 1.5e-22 79.6 34.8 3.8e-05 23.9 0.1 10.6 10 1 0 11 11 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 KND92929.1 - 2e-18 64.6 15.2 0.058 13.2 0.0 13.4 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_7 PF13176.1 KND92929.1 - 2.2e-12 45.7 33.4 0.0034 17.0 0.0 13.8 15 1 1 16 16 14 3 Tetratricopeptide repeat TPR_6 PF13174.1 KND92929.1 - 4.2e-06 26.8 31.0 22 5.7 0.0 15.8 17 0 0 17 17 16 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND92929.1 - 0.00029 20.6 13.3 6.5 6.6 0.1 7.9 5 3 1 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KND92929.1 - 0.0046 17.2 19.3 4.2 8.0 0.2 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat HemY_N PF07219.8 KND92929.1 - 0.013 15.0 4.9 0.73 9.4 0.0 4.5 4 1 1 5 5 4 0 HemY protein N-terminus Coatomer_WDAD PF04053.9 KND92929.1 - 0.023 13.5 0.3 0.067 11.9 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region TPR_20 PF14561.1 KND92929.1 - 0.046 13.8 24.7 0.46 10.6 0.4 7.3 6 2 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND92929.1 - 0.15 12.0 28.5 3.7 7.6 0.0 9.7 11 0 0 11 11 11 0 Tetratricopeptide repeat NIF3 PF01784.13 KND92930.1 - 6.3e-34 117.6 0.0 8.9e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.6 KND92931.1 - 4.5e-27 93.7 0.0 7.1e-27 93.0 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KND92931.1 - 5.1e-05 21.8 0.0 6.2e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Adaptin_N PF01602.15 KND92932.1 - 1.2e-147 492.4 2.8 1.6e-147 491.9 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KND92932.1 - 8.9e-27 94.0 0.4 1.8e-25 89.8 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KND92932.1 - 3e-17 62.6 1.2 4.5e-07 30.0 0.1 5.1 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.17 KND92932.1 - 1.8e-11 43.0 3.7 0.007 16.3 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KND92932.1 - 3.8e-05 24.0 2.0 2 9.0 0.0 5.5 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 KND92932.1 - 0.0011 18.6 0.5 1.2 9.0 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KND92932.1 - 0.012 15.0 0.1 1.5 8.0 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal UNC45-central PF11701.3 KND92932.1 - 0.045 13.3 0.3 0.72 9.4 0.0 2.6 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central BolA PF01722.13 KND92933.1 - 4.2e-22 77.8 0.0 5.1e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein WD40 PF00400.27 KND92935.1 - 1e-16 60.0 1.7 9.6e-05 22.1 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Sulfate_transp PF00916.15 KND92936.1 - 1.3e-64 217.9 7.3 2.2e-64 217.1 5.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KND92936.1 - 9.3e-26 89.3 1.8 9.3e-26 89.3 1.3 4.1 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KND92936.1 - 1.3e-06 27.7 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain DUF3511 PF12023.3 KND92936.1 - 0.13 11.6 0.1 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) 7tm_2 PF00002.19 KND92938.1 - 3.9e-08 32.6 9.9 1.2e-07 31.0 4.8 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 KND92938.1 - 4.1e-08 32.6 0.2 7.6e-08 31.7 0.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KND92938.1 - 0.0031 17.0 9.2 0.006 16.1 6.4 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF3366 PF11846.3 KND92938.1 - 0.037 13.8 3.0 0.042 13.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) Sugar_tr PF00083.19 KND92939.1 - 3.7e-05 22.4 1.2 3.7e-05 22.4 0.8 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2892 PF11127.3 KND92939.1 - 0.25 11.1 1.5 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Peptidase_M3 PF01432.15 KND92940.1 - 3.1e-143 478.1 0.0 3.9e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 KND92940.1 - 0.19 11.7 0.7 0.52 10.3 0.5 1.7 1 1 0 1 1 1 0 Effector protein MFS_1 PF07690.11 KND92941.1 - 2.8e-35 121.6 21.6 4.1e-35 121.1 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_11 PF08241.7 KND92942.1 - 7e-21 74.5 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND92942.1 - 4.5e-13 49.7 0.0 8.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND92942.1 - 1.8e-12 47.0 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND92942.1 - 2e-10 40.9 0.0 3.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND92942.1 - 2.4e-10 40.3 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND92942.1 - 2.7e-10 40.5 0.0 4.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND92942.1 - 1.3e-07 30.9 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KND92942.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND92942.1 - 0.00028 20.2 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KND92942.1 - 0.0039 16.1 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 KND92942.1 - 0.0098 15.5 0.0 0.045 13.3 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 KND92942.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 KND92942.1 - 0.035 13.1 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KND92942.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.1 KND92943.1 - 1.1e-15 57.5 0.1 4.7e-10 39.4 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KND92943.1 - 2e-12 45.8 0.5 5.7e-05 22.6 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KND92943.1 - 9.3e-12 44.6 0.0 6.8e-06 25.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KND92943.1 - 7.9e-11 40.4 0.8 0.00041 19.4 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KND92943.1 - 1.4e-08 34.2 0.5 0.00077 19.0 0.1 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KND92943.1 - 0.048 13.0 2.0 2.2 7.7 0.7 2.9 2 0 0 2 2 2 0 EF hand DUF3216 PF11505.3 KND92943.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Adaptin_N PF01602.15 KND92945.1 - 2.7e-135 451.6 10.9 3.6e-135 451.2 7.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KND92945.1 - 2.1e-18 66.8 3.1 6.8e-18 65.1 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KND92945.1 - 9.3e-16 57.8 4.7 3.1e-09 36.9 0.1 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 KND92945.1 - 2.7e-12 45.6 1.8 0.00028 20.6 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KND92945.1 - 5.7e-05 23.4 7.9 0.2 12.1 0.0 6.0 4 2 2 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 KND92945.1 - 0.00016 21.3 0.0 0.19 11.4 0.0 4.2 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 KND92945.1 - 0.00023 20.8 1.2 0.77 9.6 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KND92945.1 - 0.00026 20.4 2.2 0.2 11.0 0.0 2.9 3 0 0 3 3 3 2 CLASP N terminal DUF2435 PF10363.4 KND92945.1 - 0.11 12.4 1.2 2.6 8.0 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) DUF1077 PF06417.7 KND92946.1 - 8.4e-52 173.7 5.1 1e-51 173.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MFS_1 PF07690.11 KND92947.1 - 2.2e-53 181.2 22.3 5.6e-52 176.5 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND92947.1 - 4.2e-07 28.9 9.1 4.2e-07 28.9 6.3 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 KND92947.1 - 0.00057 18.1 7.3 0.0013 16.9 1.0 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector TMEM213 PF15192.1 KND92947.1 - 0.11 12.5 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 TMEM213 family OATP PF03137.15 KND92947.1 - 0.21 9.5 3.2 0.06 11.4 0.2 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3353 PF11833.3 KND92947.1 - 0.63 9.4 6.3 0.61 9.5 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DEAD PF00270.24 KND92948.1 - 6e-41 139.7 0.0 9.8e-41 139.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND92948.1 - 1e-17 63.7 0.0 2.3e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KND92948.1 - 3.4e-16 58.5 0.0 7.2e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KND92948.1 - 0.033 14.0 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF202 PF02656.10 KND92949.1 - 1.5e-20 73.1 1.7 9e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Abhydrolase_9_N PF15420.1 KND92949.1 - 0.2 11.3 0.2 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3112 PF11309.3 KND92949.1 - 0.41 10.4 4.7 0.89 9.3 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF1049 PF06305.6 KND92949.1 - 0.8 9.2 4.1 4.7 6.7 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ABC_tran PF00005.22 KND92950.1 - 2.6e-21 76.3 0.0 7.7e-10 39.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND92950.1 - 1.1e-08 35.4 0.0 0.015 15.2 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KND92950.1 - 1.6e-07 32.2 0.0 0.0044 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KND92950.1 - 2.1e-07 30.7 0.1 0.0006 19.6 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KND92950.1 - 7.4e-05 22.8 0.0 0.86 9.7 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 KND92950.1 - 0.00043 20.1 0.1 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND92950.1 - 0.00047 20.1 0.1 0.56 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KND92950.1 - 0.001 18.5 0.1 0.24 10.9 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KND92950.1 - 0.001 18.5 0.1 2.5 7.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KND92950.1 - 0.0075 16.6 0.0 0.92 9.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KND92950.1 - 0.0099 15.3 0.0 0.57 9.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 KND92950.1 - 0.014 15.1 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KND92950.1 - 0.037 13.4 0.0 6 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 KND92950.1 - 0.04 13.4 0.2 3.6 7.0 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Miro PF08477.8 KND92950.1 - 0.043 14.3 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 KND92950.1 - 0.043 13.7 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KND92950.1 - 0.052 13.8 0.0 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KND92950.1 - 0.056 13.6 0.0 10 6.3 0.0 2.6 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.7 KND92950.1 - 0.058 13.0 0.0 13 5.4 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.1 KND92950.1 - 0.13 12.2 0.0 7.1 6.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 KND92950.1 - 0.18 11.3 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KND92950.1 - 0.46 8.8 0.1 0.68 8.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.6 KND92951.1 - 2.5e-25 88.9 0.0 3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 KND92952.1 - 3.3e-12 46.2 0.0 6.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KND92952.1 - 7.1e-05 22.1 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KND92952.1 - 0.00036 20.6 0.0 0.00077 19.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PPR_2 PF13041.1 KND92953.1 - 1.2e-45 153.2 4.2 2.2e-09 37.1 0.0 14.7 9 4 7 16 16 16 10 PPR repeat family PPR PF01535.15 KND92953.1 - 8.1e-28 94.4 23.2 0.00029 20.5 0.0 14.1 16 1 0 16 16 16 6 PPR repeat PPR_3 PF13812.1 KND92953.1 - 2.2e-26 89.8 18.7 8.9e-05 22.4 0.0 15.3 16 1 1 17 17 17 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 KND92953.1 - 9.9e-22 76.1 0.2 1.8e-08 33.6 0.0 9.3 10 0 0 10 10 10 3 PPR repeat RPM2 PF08579.6 KND92953.1 - 0.0089 16.1 0.0 0.19 11.8 0.0 3.0 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 KND92953.1 - 0.017 14.4 0.0 4.7 6.5 0.0 3.6 4 0 0 4 4 4 0 Mitochondrial ATPase expression GHMP_kinases_N PF00288.21 KND92954.1 - 1.9e-15 56.6 2.0 5.1e-15 55.3 1.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND92954.1 - 1e-07 32.0 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal SpoVIF PF14069.1 KND92954.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Stage VI sporulation protein F Phage-scaffold PF09306.5 KND92954.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Kinesin PF00225.18 KND92955.1 - 1.4e-81 273.7 0.0 1.8e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain RNA_pol_Rpo13 PF12136.3 KND92955.1 - 0.054 13.2 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain HHH_3 PF12836.2 KND92955.1 - 0.071 13.0 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif AIM24 PF01987.12 KND92956.1 - 6.1e-45 153.3 0.0 8.4e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 KND92956.1 - 0.13 12.6 1.0 0.43 11.0 0.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) MFS_1 PF07690.11 KND92957.1 - 3.9e-28 98.1 68.6 1.5e-19 69.9 25.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KND92957.1 - 0.00029 19.5 44.7 0.012 14.2 13.6 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KND92957.1 - 0.014 15.1 3.7 0.014 15.1 2.5 2.7 3 0 0 3 3 3 0 MFS_1 like family DUF3169 PF11368.3 KND92957.1 - 3.4 6.8 11.0 3.7 6.6 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Acetyltransf_1 PF00583.19 KND92958.1 - 9e-09 35.2 0.1 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND92958.1 - 6.8e-06 26.1 0.0 0.00093 19.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND92958.1 - 9.2e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND92958.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KND92958.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND92958.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Zip PF02535.17 KND92961.1 - 5.1e-22 78.2 42.9 7.4e-10 38.3 4.9 3.9 3 1 1 4 4 4 3 ZIP Zinc transporter Peptidase_S8 PF00082.17 KND92962.1 - 4.3e-42 144.2 1.8 5.9e-42 143.7 1.2 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KND92962.1 - 0.00031 21.1 0.0 0.00074 19.9 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Tim17 PF02466.14 KND92964.1 - 9.2e-07 28.9 4.1 1.7e-06 28.1 2.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MutS_V PF00488.16 KND92965.1 - 1.5e-96 322.3 0.0 2.2e-96 321.8 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND92965.1 - 2.8e-39 135.0 0.5 5.6e-39 134.0 0.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KND92965.1 - 2.1e-22 79.6 1.0 4.3e-20 72.1 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 KND92965.1 - 8.6e-18 64.4 0.0 5.2e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 KND92965.1 - 5.2e-12 45.7 2.4 2e-11 43.8 1.2 2.4 2 0 0 2 2 2 1 MutS family domain IV Peptidase_M16 PF00675.15 KND92965.1 - 0.053 13.2 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Cpn60_TCP1 PF00118.19 KND92966.1 - 5e-142 473.9 7.4 5.8e-142 473.7 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 KND92967.1 - 4.4e-21 75.2 0.0 7.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 KND92967.1 - 2.2e-19 69.0 0.0 4.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KND92967.1 - 9.9e-17 60.6 0.0 2.7e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Acetyltransf_7 PF13508.1 KND92968.1 - 0.035 14.2 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 KND92969.1 - 3.1e-05 23.8 5.8 5.7e-05 22.9 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND92969.1 - 0.055 12.0 0.3 0.14 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Sld5 PF05916.6 KND92970.1 - 9.8e-26 90.1 0.0 1.5e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF2605 PF10792.4 KND92970.1 - 0.021 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Peptidase_M28 PF04389.12 KND92971.1 - 3.7e-23 82.1 0.1 1.2e-22 80.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KND92971.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Gar1 PF04410.9 KND92972.1 - 4.3e-50 169.1 0.2 4.3e-50 169.1 0.2 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Zip PF02535.17 KND92972.1 - 0.19 10.7 0.0 0.19 10.7 0.0 2.0 2 1 0 2 2 2 0 ZIP Zinc transporter Glyco_transf_22 PF03901.12 KND92973.1 - 2.7e-88 296.7 22.1 3.2e-88 296.5 15.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.20 KND92974.1 - 0.0011 18.1 0.1 0.012 14.7 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Asp_protease PF09668.5 KND92975.1 - 9.4e-61 202.8 0.2 1.4e-60 202.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KND92975.1 - 2.6e-13 50.2 0.2 9.1e-13 48.5 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 KND92975.1 - 4.1e-10 38.9 0.0 8.8e-10 37.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 KND92975.1 - 3.3e-07 30.3 0.0 7.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 KND92975.1 - 6.6e-07 28.9 0.4 1.5e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 KND92975.1 - 7.6e-07 28.8 1.6 2.1e-06 27.4 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KND92975.1 - 1.9e-05 24.4 0.0 5.1e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KND92975.1 - 0.0055 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 KND92975.1 - 0.0099 16.1 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 YukD PF08817.5 KND92975.1 - 0.084 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Acyl-CoA_ox_N PF14749.1 KND92975.1 - 0.2 11.9 1.4 0.35 11.1 1.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Acetyltransf_1 PF00583.19 KND92976.1 - 3.2e-05 23.8 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GATase_2 PF00310.16 KND92977.1 - 1.4e-17 63.4 0.0 1.2e-13 50.5 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 KND92977.1 - 4.5e-12 45.7 0.1 9.8e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 KND92977.1 - 2.4e-11 43.7 0.0 6.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KND92977.1 - 1.6e-10 40.7 0.0 3.6e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KND92977.1 - 0.078 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Methyltransf_8 PF05148.10 KND92978.1 - 7.6e-59 198.9 0.0 3.8e-56 190.1 0.0 3.0 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KND92978.1 - 4.1e-05 23.9 0.0 0.00011 22.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Proteasome PF00227.21 KND92979.1 - 1.7e-55 187.2 0.1 2.3e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KND92979.1 - 1.1e-13 50.2 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KND92979.1 - 0.0037 16.9 0.1 0.099 12.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 KND92980.1 - 2.6e-12 46.0 0.1 5.6e-10 38.3 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND92980.1 - 1.3e-05 25.0 11.7 2.2e-05 24.2 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND92980.1 - 0.0048 15.8 1.6 0.025 13.4 1.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 KND92981.1 - 2.9e-68 229.8 0.0 4e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND92981.1 - 2.6e-08 33.5 0.0 6.8e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KND92981.1 - 2.2e-06 27.2 2.7 4.1e-06 26.4 1.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 KND92981.1 - 2.9e-06 26.8 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KND92981.1 - 0.0025 17.4 2.2 0.0087 15.7 1.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND92981.1 - 0.0036 17.1 2.3 0.0077 16.0 1.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND92981.1 - 0.0054 16.7 0.9 0.0054 16.7 0.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND92981.1 - 0.029 14.0 3.6 0.077 12.6 2.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND92981.1 - 0.29 11.0 2.3 0.98 9.3 1.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Spc97_Spc98 PF04130.8 KND92982.1 - 7.7e-123 410.6 0.8 1.1e-122 410.1 0.5 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family HSP70 PF00012.15 KND92983.1 - 8.6e-263 872.7 14.7 9.9e-263 872.5 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND92983.1 - 8.5e-13 47.5 4.4 8e-11 41.1 0.9 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KND92983.1 - 0.00011 21.8 0.1 0.00031 20.4 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KND92983.1 - 0.0012 18.6 6.3 1.4 8.7 0.2 4.4 1 1 1 2 2 2 2 Cell division protein FtsA HisKA_3 PF07730.8 KND92984.1 - 0.027 14.8 4.5 4.4 7.7 0.1 3.5 4 0 0 4 4 4 0 Histidine kinase YqjK PF13997.1 KND92984.1 - 0.028 14.5 0.4 21 5.3 0.0 3.5 2 1 1 3 3 3 0 YqjK-like protein Ribonuclease_T2 PF00445.13 KND92985.1 - 3.2e-23 82.3 0.1 6.3e-23 81.3 0.1 1.4 1 1 0 1 1 1 1 Ribonuclease T2 family Beta-lactamase PF00144.19 KND92986.1 - 2.9e-38 131.7 4.0 4.3e-38 131.1 2.8 1.1 1 0 0 1 1 1 1 Beta-lactamase ABC_membrane PF00664.18 KND92987.1 - 2.4e-36 125.5 11.9 3e-36 125.2 8.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KND92987.1 - 1.5e-33 116.0 0.0 7e-33 113.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 KND92987.1 - 8.8e-06 25.8 0.0 4.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KND92987.1 - 4.8e-05 23.4 0.1 0.017 15.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KND92987.1 - 0.00025 20.3 0.0 0.015 14.5 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KND92987.1 - 0.00035 21.3 0.0 0.00076 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND92987.1 - 0.00044 20.1 0.0 0.003 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KND92987.1 - 0.0011 19.1 0.0 0.0043 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND92987.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KND92987.1 - 0.0049 16.3 0.1 0.029 13.8 0.0 2.0 1 1 1 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KND92987.1 - 0.013 14.9 0.1 0.034 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KND92987.1 - 0.015 15.4 0.0 0.078 13.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KND92987.1 - 0.018 14.9 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KND92987.1 - 0.035 14.0 0.3 0.41 10.5 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KND92987.1 - 0.041 13.5 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KND92987.1 - 0.043 13.7 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KND92987.1 - 0.049 12.7 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KND92987.1 - 0.052 12.9 0.2 0.21 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KND92987.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 KND92987.1 - 0.053 13.8 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 KND92987.1 - 0.08 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF1016 PF06250.6 KND92987.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) Myb_DNA-bind_6 PF13921.1 KND92988.1 - 1.2e-14 54.1 10.1 7e-12 45.2 0.5 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KND92988.1 - 2.3e-13 49.9 1.8 5.1e-08 32.8 0.1 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain AAA_16 PF13191.1 KND92989.1 - 2.4e-07 30.9 1.8 1.6e-05 25.0 0.4 3.0 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KND92989.1 - 1.4e-05 24.8 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KND92989.1 - 0.0021 17.5 0.1 0.014 14.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 KND92989.1 - 0.02 15.4 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 KND92989.1 - 0.03 14.4 0.1 0.076 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KND92989.1 - 0.031 13.7 0.0 0.1 12.0 0.0 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 KND92989.1 - 0.035 13.0 0.1 0.09 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 KND92989.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FMO-like PF00743.14 KND92990.1 - 3.2e-38 131.2 0.0 5.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND92990.1 - 6.1e-18 65.6 0.0 1.4e-16 61.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND92990.1 - 7.9e-08 32.2 0.0 5.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND92990.1 - 1.4e-07 31.5 0.0 1.7e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND92990.1 - 4.7e-05 22.4 0.0 0.0058 15.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KND92990.1 - 8.9e-05 21.5 0.1 0.46 9.3 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KND92990.1 - 0.00026 20.8 1.5 0.0014 18.4 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 KND92990.1 - 0.0011 18.9 0.1 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KND92990.1 - 0.023 13.7 0.0 8.4 5.3 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase ELFV_dehydrog PF00208.16 KND92990.1 - 0.072 12.6 1.6 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 KND92990.1 - 0.12 12.4 1.0 34 4.5 0.1 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KND92990.1 - 0.16 11.9 1.7 12 5.9 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain 3HCDH_N PF02737.13 KND92990.1 - 0.49 10.0 2.9 0.82 9.2 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KND92990.1 - 1.2 8.3 2.5 19 4.3 0.2 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KND92990.1 - 1.8 8.4 6.4 2.6 7.8 0.3 2.4 2 0 0 2 2 2 0 ThiF family DUF208 PF02677.9 KND92992.1 - 0.058 13.1 0.4 0.058 13.1 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized BCR, COG1636 MFS_1 PF07690.11 KND92993.1 - 1.4e-31 109.4 43.0 1.9e-30 105.7 29.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 KND92993.1 - 0.039 13.9 0.8 0.084 12.9 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CCSMST1 PF15013.1 KND92993.1 - 0.053 13.4 0.1 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 CCSMST1 family Fringe PF02434.11 KND92994.1 - 1.8e-07 30.6 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KND92994.1 - 0.00018 21.1 1.9 0.00037 20.1 1.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KND92994.1 - 0.016 14.9 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 KND92994.1 - 0.045 13.3 0.2 0.099 12.2 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain Fungal_trans_2 PF11951.3 KND92995.1 - 1.6e-33 115.8 0.1 6.5e-24 84.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND92995.1 - 1.2e-08 34.6 12.2 2.3e-08 33.8 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KND92995.1 - 0.097 12.4 5.0 0.27 11.0 3.5 1.8 1 0 0 1 1 1 0 AT hook motif INCENP_ARK-bind PF03941.10 KND92997.1 - 9.2e-22 76.6 0.8 2.7e-21 75.1 0.5 1.9 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region RibD_C PF01872.12 KND92998.1 - 2e-35 122.2 0.0 3.2e-35 121.5 0.0 1.3 1 1 0 1 1 1 1 RibD C-terminal domain G-alpha PF00503.15 KND93000.1 - 4.3e-123 410.8 2.1 5.1e-123 410.6 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KND93000.1 - 1.2e-14 53.9 0.5 8.4e-09 34.9 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND93000.1 - 0.00017 20.8 0.2 0.12 11.4 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KND93000.1 - 0.0016 18.9 0.0 0.97 9.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KND93000.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.17 KND93001.1 - 2.8e-203 676.7 9.0 3.5e-203 676.3 6.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KND93001.1 - 1.2e-25 89.0 3.2 1.2e-25 89.0 2.2 3.0 4 0 0 4 4 4 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.4 KND93001.1 - 0.023 14.8 0.3 0.47 10.6 0.1 3.1 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal ABC_tran PF00005.22 KND93002.1 - 2.2e-51 173.7 0.0 5.5e-29 101.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND93002.1 - 2.8e-27 95.8 24.0 4.6e-15 55.7 1.6 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KND93002.1 - 3.9e-10 39.3 2.2 0.015 14.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND93002.1 - 6.1e-09 35.2 1.0 0.0014 18.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KND93002.1 - 2.2e-08 34.6 0.1 1.4e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KND93002.1 - 2.5e-08 34.2 0.0 0.078 12.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KND93002.1 - 3e-08 33.2 0.0 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KND93002.1 - 5.3e-06 25.7 0.1 0.01 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KND93002.1 - 1.3e-05 24.8 0.6 0.034 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KND93002.1 - 2.4e-05 23.8 0.0 0.044 13.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 KND93002.1 - 6.3e-05 23.1 0.2 0.59 10.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 KND93002.1 - 7.7e-05 23.1 0.1 0.42 11.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KND93002.1 - 0.00011 22.1 0.2 0.22 11.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KND93002.1 - 0.00011 22.0 2.1 0.086 12.6 0.1 2.6 2 0 0 2 2 2 2 Dynamin family DUF87 PF01935.12 KND93002.1 - 0.00017 21.4 2.9 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KND93002.1 - 0.00023 20.8 0.1 0.07 12.8 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KND93002.1 - 0.00033 21.4 0.8 1.2 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KND93002.1 - 0.00037 20.2 0.5 0.092 12.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KND93002.1 - 0.00048 20.1 3.7 0.64 9.9 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KND93002.1 - 0.00065 18.6 0.7 0.71 8.7 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein SbcCD_C PF13558.1 KND93002.1 - 0.00083 19.2 0.0 1.3 9.0 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KND93002.1 - 0.0017 18.0 0.2 2.2 7.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.17 KND93002.1 - 0.002 17.0 0.2 3.8 6.2 0.0 3.5 3 1 0 3 3 3 0 NB-ARC domain Viral_helicase1 PF01443.13 KND93002.1 - 0.003 17.1 0.0 2.3 7.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KND93002.1 - 0.0096 16.2 0.1 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KND93002.1 - 0.013 14.9 1.0 3.4 7.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KND93002.1 - 0.018 14.7 0.5 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 KND93002.1 - 0.024 14.5 0.0 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KND93002.1 - 0.059 12.2 1.2 4.1 6.2 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.7 KND93002.1 - 0.074 12.3 2.5 1.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.13 KND93002.1 - 0.096 11.6 0.3 5.5 5.9 0.0 2.4 3 0 0 3 3 2 0 Septin AAA_15 PF13175.1 KND93002.1 - 0.096 11.7 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KND93002.1 - 0.1 12.2 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase ABC_ATPase PF09818.4 KND93002.1 - 0.11 11.1 3.7 6.6 5.1 0.1 3.3 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DUF2075 PF09848.4 KND93002.1 - 0.13 11.1 0.2 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.11 KND93002.1 - 0.14 11.2 0.3 5.5 6.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_14 PF13173.1 KND93002.1 - 0.14 12.0 0.1 9.5 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 KND93002.1 - 0.17 11.3 1.0 5.5 6.4 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KND93002.1 - 0.19 10.7 0.2 3.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 KND93002.1 - 0.26 10.8 0.3 73 2.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain His_Phos_1 PF00300.17 KND93003.1 - 8e-08 32.5 0.0 0.00014 22.0 0.0 2.7 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CorA PF01544.13 KND93003.1 - 0.043 12.8 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 KND93005.1 - 1.5e-46 158.7 0.0 2.6e-46 157.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93005.1 - 5.4e-16 58.4 0.0 7e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND93005.1 - 0.00055 19.7 0.8 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KND93005.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPTA PF01239.17 KND93006.1 - 4.5e-35 117.5 4.1 2.6e-07 29.7 0.0 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.1 KND93006.1 - 0.15 11.5 0.2 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Gag_spuma PF03276.9 KND93007.1 - 6.9 4.8 18.4 0.024 12.9 6.2 1.6 2 0 0 2 2 2 0 Spumavirus gag protein Sec34 PF04136.10 KND93008.1 - 2.4e-27 95.5 0.1 7.2e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 Sec34-like family RCC1 PF00415.13 KND93009.1 - 4.8e-23 81.1 4.2 1.9e-06 27.9 0.0 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KND93009.1 - 9.5e-10 37.8 25.8 5.1e-07 29.1 0.0 7.1 7 2 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.22 KND93010.1 - 1e-48 165.7 0.0 1.7e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KND93010.1 - 1.8e-05 24.7 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KND93010.1 - 0.0075 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KND93010.1 - 0.016 15.4 0.1 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Prefoldin PF02996.12 KND93013.1 - 3.4e-34 117.0 0.1 3.4e-34 117.0 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 KND93013.1 - 0.0023 17.6 4.4 0.019 14.7 0.0 2.9 1 1 3 4 4 4 1 Prefoldin subunit HR1 PF02185.11 KND93013.1 - 0.01 15.5 0.1 0.068 12.9 0.0 2.2 2 0 0 2 2 2 0 Hr1 repeat DUF4201 PF13870.1 KND93013.1 - 0.014 14.8 3.8 0.34 10.3 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.6 KND93013.1 - 0.014 15.7 3.3 1.7 9.1 0.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Filament PF00038.16 KND93013.1 - 0.018 14.5 4.0 0.24 10.8 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein End3 PF12761.2 KND93013.1 - 0.038 13.6 1.7 0.28 10.7 0.3 2.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 VanZ PF04892.7 KND93014.1 - 3.3e-09 36.8 1.0 4.6e-09 36.3 0.7 1.2 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.20 KND93015.1 - 7.7e-21 73.8 0.4 2.5e-19 68.9 0.2 2.6 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 KND93015.1 - 9.4e-11 41.2 0.0 1.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.1 KND93015.1 - 0.68 10.2 15.7 0.69 10.2 1.0 4.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SHMT PF00464.14 KND93016.1 - 2e-203 675.1 0.0 2.3e-203 674.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KND93016.1 - 4.1e-05 22.4 0.0 6.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KND93016.1 - 5.7e-05 22.2 0.0 9.7e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KND93016.1 - 0.0089 15.2 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase NAD_binding_6 PF08030.7 KND93017.1 - 4.2e-13 49.4 0.0 8.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KND93017.1 - 2.6e-11 43.7 12.5 6.8e-11 42.3 8.7 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KND93017.1 - 3.2e-08 33.3 0.0 1.5e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain Serglycin PF04360.7 KND93017.1 - 1.2e-07 31.6 0.2 2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Serglycin NAD_binding_1 PF00175.16 KND93017.1 - 0.00095 19.7 0.1 0.62 10.6 0.1 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain ADH_zinc_N PF00107.21 KND93018.1 - 8.3e-18 64.1 0.5 1.3e-17 63.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND93018.1 - 2e-09 38.4 0.1 5.5e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND93018.1 - 1.6e-05 24.5 0.0 5.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain KH_1 PF00013.24 KND93019.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 KH domain KH_3 PF13014.1 KND93019.1 - 0.069 12.8 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 KH domain PI3_PI4_kinase PF00454.22 KND93020.1 - 6.3e-41 140.3 0.0 9.1e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_23 PF13489.1 KND93021.1 - 1.2e-14 54.3 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND93021.1 - 2.5e-11 43.9 0.0 3.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND93021.1 - 8.8e-10 39.1 0.1 6.8e-09 36.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND93021.1 - 1.1e-09 38.0 0.0 3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND93021.1 - 3.9e-09 36.8 0.0 7.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND93021.1 - 1.6e-06 28.4 0.0 3.8e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND93021.1 - 6.2e-05 22.1 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KND93021.1 - 0.00045 19.3 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KND93021.1 - 0.0024 17.0 0.0 0.0074 15.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KND93021.1 - 0.0071 16.3 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND93021.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KND93021.1 - 0.038 13.9 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase FmrO PF07091.6 KND93021.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_29 PF03141.11 KND93021.1 - 0.2 9.9 0.3 0.85 7.8 0.2 1.8 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acetyltransf_3 PF13302.1 KND93022.1 - 1.7e-12 47.7 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND93022.1 - 1.8e-09 37.5 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KND93022.1 - 8.7e-09 35.5 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND93022.1 - 0.00073 19.4 0.0 0.0031 17.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND93022.1 - 0.0034 17.1 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KND93022.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 KND93023.1 - 2.6e-18 65.8 0.1 6.6e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND93023.1 - 1.4e-09 37.7 0.2 2.6e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ribonuc_L-PSP PF01042.16 KND93024.1 - 4.3e-27 94.2 0.0 4.8e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulf_transp PF04143.9 KND93025.1 - 5.2e-15 55.1 23.0 4e-10 39.5 5.2 4.6 4 1 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 KND93025.1 - 0.0043 16.7 8.2 0.0043 16.7 5.7 5.1 5 2 0 5 5 5 1 Domain of unknown function (DUF4341) YqeY PF09424.5 KND93027.1 - 9.5e-23 80.6 6.3 1.1e-22 80.4 4.3 1.1 1 0 0 1 1 1 1 Yqey-like protein POTRA_2 PF08479.6 KND93027.1 - 0.08 12.6 0.1 0.9 9.2 0.1 2.3 1 1 0 1 1 1 0 POTRA domain, ShlB-type GatB_Yqey PF02637.13 KND93027.1 - 0.097 12.3 1.4 0.15 11.7 1.0 1.6 1 1 0 1 1 1 0 GatB domain Sec62 PF03839.11 KND93028.1 - 1.2e-49 168.7 1.8 1.2e-49 168.7 1.3 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 Macoilin PF09726.4 KND93028.1 - 0.0081 14.5 0.0 0.013 13.8 0.0 1.3 1 1 0 1 1 1 1 Transmembrane protein Zip PF02535.17 KND93028.1 - 0.009 15.0 5.2 2.2 7.2 5.1 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter DUF4199 PF13858.1 KND93028.1 - 1.4 8.8 8.1 0.16 11.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SelP_N PF04592.9 KND93028.1 - 2.2 7.6 9.9 4.5 6.5 6.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region U1snRNP70_N PF12220.3 KND93028.1 - 3.9 7.8 9.1 8.7 6.7 0.0 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Corona_M PF01635.13 KND93028.1 - 9.6 5.0 9.8 18 4.2 6.8 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Acetyltransf_1 PF00583.19 KND93029.1 - 2.7e-10 40.1 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KND93029.1 - 2.8e-08 33.3 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KND93029.1 - 1.8e-07 31.3 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND93029.1 - 4.7e-06 26.6 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND93029.1 - 0.0015 18.6 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND93029.1 - 0.058 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 KND93030.1 - 4.3e-13 49.3 3.3 1.7e-08 34.4 0.4 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KND93030.1 - 8.1e-10 39.2 0.4 4.5e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KND93030.1 - 0.00014 21.7 0.0 0.33 10.9 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Herpes_US9 PF06072.6 KND93030.1 - 0.098 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 p450 PF00067.17 KND93031.1 - 5.4e-67 226.3 0.0 1.6e-40 139.0 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 Aldedh PF00171.17 KND93032.1 - 3.4e-166 553.1 0.4 2.9e-153 510.5 0.1 2.0 1 1 0 2 2 2 2 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 KND93033.1 - 2.3e-84 283.5 0.0 2.9e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KND93033.1 - 0.00019 21.3 0.1 0.00036 20.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND93033.1 - 0.037 14.0 1.5 0.1 12.6 1.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND93033.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KND93033.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KND93034.1 - 2.3e-24 86.5 0.0 6.4e-24 85.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KND93034.1 - 5.9e-15 54.4 0.1 7.8e-14 50.7 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KND93034.1 - 4.1e-08 32.5 0.0 7.6e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KND93034.1 - 1.9e-07 31.0 0.0 4.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND93034.1 - 0.0002 21.3 0.0 0.0085 15.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KND93034.1 - 0.00036 19.5 0.1 0.69 8.7 0.1 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 KND93034.1 - 0.00083 18.3 1.2 0.037 12.9 0.3 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KND93034.1 - 0.0025 16.9 1.2 0.0049 15.9 0.1 1.9 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 KND93034.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KND93034.1 - 0.026 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain N2227 PF07942.7 KND93034.1 - 0.048 12.6 0.9 0.21 10.5 0.6 1.8 1 1 0 1 1 1 0 N2227-like protein Shikimate_DH PF01488.15 KND93034.1 - 0.21 11.6 0.3 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KND93035.1 - 1.4e-23 83.6 7.8 2.5e-22 79.5 5.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND93035.1 - 1.3e-19 70.9 0.5 2.9e-17 63.2 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND93035.1 - 5.3e-09 35.9 2.1 5.7e-07 29.3 0.4 2.2 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.13 KND93035.1 - 0.088 12.4 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain T2SI PF02501.12 KND93035.1 - 0.12 12.3 0.1 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I DUF2463 PF09591.5 KND93036.1 - 0.0041 16.7 0.9 0.63 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2463) VMA21 PF09446.5 KND93036.1 - 3.6 7.5 8.0 0.67 9.9 2.1 2.4 3 0 0 3 3 3 0 VMA21-like domain HSF_DNA-bind PF00447.12 KND93037.1 - 3.7e-33 113.7 0.1 6.6e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KND93037.1 - 2.5e-17 62.9 0.0 7.8e-17 61.2 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain NPV_P10 PF05531.7 KND93037.1 - 0.041 14.1 0.8 0.08 13.2 0.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 KND93037.1 - 0.11 12.9 1.2 0.24 11.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) W2 PF02020.13 KND93038.1 - 1.3e-18 66.7 0.9 3.6e-18 65.2 0.6 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KND93038.1 - 4.3e-11 41.8 8.0 1.4e-06 27.5 2.0 3.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KND93038.1 - 1.5e-06 27.6 6.2 0.0037 16.7 1.3 3.0 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KND93038.1 - 0.00058 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KND93038.1 - 0.0015 18.5 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 MobA-like NTP transferase domain UDPGT PF00201.13 KND93039.1 - 7.3e-11 41.2 0.0 2.2e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KND93039.1 - 8.8e-05 22.2 0.9 0.00015 21.5 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 KND93039.1 - 0.019 14.1 0.1 6.1 5.9 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 KND93039.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.1 KND93039.1 - 0.28 11.2 12.9 0.023 14.8 4.2 2.5 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain Ribosomal_S17 PF00366.15 KND93040.1 - 6.4e-09 35.7 0.4 1.1e-08 35.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 NARP1 PF12569.3 KND93040.1 - 0.7 8.5 4.9 0.89 8.2 3.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EMG1 PF03587.9 KND93041.1 - 1.1e-78 263.2 0.0 1.2e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TPR_11 PF13414.1 KND93042.1 - 2e-25 88.2 8.1 5.8e-09 35.4 0.1 5.6 5 1 1 6 6 5 4 TPR repeat DnaJ PF00226.26 KND93042.1 - 3.1e-24 84.4 2.8 3.1e-24 84.4 1.9 2.5 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.23 KND93042.1 - 8.4e-21 72.6 0.1 0.0031 17.0 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KND93042.1 - 1.2e-17 64.0 8.1 9.4e-05 22.9 0.1 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND93042.1 - 3.6e-17 60.8 10.3 0.0097 15.7 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 KND93042.1 - 1.3e-13 50.5 4.8 0.00092 19.0 0.1 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KND93042.1 - 1.1e-12 46.7 2.3 0.03 14.1 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND93042.1 - 6.7e-12 44.9 11.8 0.13 12.9 0.0 7.9 4 4 4 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KND93042.1 - 3e-11 42.5 2.4 0.0033 17.5 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND93042.1 - 6.8e-10 39.1 11.2 0.0001 22.5 0.1 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KND93042.1 - 3.4e-08 33.5 2.4 0.063 13.4 0.3 4.4 4 1 3 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KND93042.1 - 4.9e-07 29.5 9.6 0.14 12.0 0.1 5.9 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KND93042.1 - 3.1e-06 27.2 12.8 2.7 8.6 0.0 7.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND93042.1 - 0.00022 20.7 7.0 1.9 8.4 0.1 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KND93042.1 - 0.046 13.6 1.5 4 7.4 0.0 3.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 KND93042.1 - 0.13 12.3 2.3 3.2 7.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Enkurin PF13864.1 KND93042.1 - 0.16 12.2 9.8 3 8.1 0.3 4.0 4 0 0 4 4 4 0 Calmodulin-binding CENP-Q PF13094.1 KND93042.1 - 0.96 9.4 5.8 5.3 7.0 0.1 3.1 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit BTAD PF03704.12 KND93042.1 - 1.8 8.8 11.3 2.9 8.1 0.0 4.7 3 2 1 4 4 4 0 Bacterial transcriptional activator domain APG9 PF04109.11 KND93043.1 - 7.1e-156 518.7 3.4 1e-155 518.2 2.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.6 KND93044.1 - 5.1e-202 672.3 0.0 5.8e-202 672.1 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG5 PF10392.4 KND93044.1 - 0.0086 16.0 0.3 0.05 13.5 0.1 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 AAA PF00004.24 KND93045.1 - 1.6e-38 131.9 0.0 3e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND93045.1 - 7.5e-07 29.3 0.2 0.00012 22.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.5 KND93045.1 - 6.8e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KND93045.1 - 0.00013 21.1 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KND93045.1 - 0.0005 18.9 0.0 0.00077 18.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KND93045.1 - 0.00062 19.4 0.0 0.0025 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KND93045.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KND93045.1 - 0.0022 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 KND93045.1 - 0.0024 17.4 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KND93045.1 - 0.0031 16.7 0.1 0.0078 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KND93045.1 - 0.0047 16.9 0.1 0.0047 16.9 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KND93045.1 - 0.0051 16.5 0.2 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KND93045.1 - 0.0073 16.2 0.0 0.068 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND93045.1 - 0.0085 16.9 0.0 0.033 15.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KND93045.1 - 0.02 14.3 0.2 0.22 10.8 0.1 2.5 2 1 1 3 3 2 0 AAA domain AAA_33 PF13671.1 KND93045.1 - 0.021 14.6 1.1 0.03 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 KND93045.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 KND93045.1 - 0.051 13.2 0.1 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 KND93045.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KND93045.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 KND93045.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KND93045.1 - 0.21 11.5 0.1 0.21 11.5 0.0 2.2 3 0 0 3 3 1 0 AAA domain FA_desaturase PF00487.19 KND93046.1 - 2.9e-40 138.3 25.0 4.7e-40 137.6 17.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KND93046.1 - 1.2e-14 53.8 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.3 KND93047.1 - 1.4e-80 268.7 4.2 1.4e-80 268.7 2.9 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KND93047.1 - 2.7e-48 162.3 0.1 4.1e-42 142.5 0.0 5.2 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KND93047.1 - 2e-11 42.9 1.3 0.00013 21.7 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KND93047.1 - 7e-09 35.9 3.1 0.00042 20.7 0.1 5.5 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 KND93047.1 - 1.2e-07 31.8 0.9 0.0088 16.3 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats CLASP_N PF12348.3 KND93047.1 - 0.0003 20.2 0.1 8.4 5.6 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal Arm PF00514.18 KND93047.1 - 0.0016 18.1 0.0 0.55 10.1 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 KND93047.1 - 0.035 14.0 0.0 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Sigma70_ner PF04546.8 KND93047.1 - 0.96 9.0 6.4 1.9 8.0 4.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Mito_carr PF00153.22 KND93049.1 - 1.1e-53 178.9 7.5 2.6e-23 81.5 0.0 5.0 3 2 1 4 4 4 4 Mitochondrial carrier protein Methyltransf_PK PF05891.7 KND93053.1 - 5e-77 258.0 0.0 5.7e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KND93053.1 - 0.00018 21.2 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND93053.1 - 0.0056 17.1 0.0 0.0092 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND93053.1 - 0.038 14.5 0.0 0.084 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF913 PF06025.7 KND93055.1 - 0.13 10.9 3.7 0.19 10.4 2.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_DNAp_acc PF04929.7 KND93055.1 - 0.19 10.6 6.2 0.28 10.1 4.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FimP PF09766.4 KND93055.1 - 0.2 10.7 13.4 0.25 10.3 9.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein RCR PF12273.3 KND93055.1 - 0.22 12.1 8.8 0.32 11.5 6.1 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Zip PF02535.17 KND93055.1 - 0.41 9.6 1.7 0.57 9.1 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.3 KND93055.1 - 0.53 8.8 7.1 0.65 8.5 4.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FLO_LFY PF01698.11 KND93055.1 - 1.2 7.8 7.8 1.6 7.4 5.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 KND93055.1 - 3.4 6.9 18.1 5.2 6.3 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RP-C_C PF11800.3 KND93055.1 - 3.8 7.1 7.3 5.7 6.5 5.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Stomoxyn PF11585.3 KND93056.1 - 0.43 10.4 2.6 2.9 7.7 0.7 2.3 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn AFG1_ATPase PF03969.11 KND93058.1 - 2.7e-93 312.6 0.0 8e-89 297.9 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 KND93058.1 - 0.0012 18.5 0.1 1.5 8.4 0.0 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.1 KND93058.1 - 0.0049 16.8 0.1 0.98 9.3 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND93058.1 - 0.0059 16.7 0.0 0.024 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND93058.1 - 0.0084 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 KND93058.1 - 0.16 12.0 0.0 0.9 9.5 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain SH3_9 PF14604.1 KND93059.1 - 8.3e-11 41.3 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND93059.1 - 3e-06 26.5 0.0 4.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KND93059.1 - 8.7e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4229 PF14012.1 KND93059.1 - 0.21 11.4 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Herpes_gE PF02480.11 KND93059.1 - 0.3 9.3 0.0 2.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E CVNH PF08881.5 KND93060.1 - 4.8e-10 39.5 0.0 7.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 CVNH domain Metallophos PF00149.23 KND93062.1 - 1.3e-35 122.6 0.6 8.1e-29 100.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase RPAP1_C PF08620.5 KND93063.1 - 3.4e-29 100.5 0.5 6e-29 99.7 0.0 1.7 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KND93063.1 - 1.4e-14 53.3 3.3 2.6e-14 52.5 2.3 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF3503 PF12011.3 KND93063.1 - 0.033 13.9 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) GIDA_assoc_3 PF13932.1 KND93063.1 - 0.085 12.9 0.3 0.2 11.7 0.2 1.7 1 1 0 1 1 1 0 GidA associated domain 3 eIF2A PF08662.6 KND93064.1 - 3.7e-76 255.1 0.0 8.2e-76 254.0 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.1 KND93064.1 - 0.0091 16.0 0.5 0.0091 16.0 0.3 3.0 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 WD40 PF00400.27 KND93064.1 - 0.021 14.6 0.2 6.6 6.7 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat CP2 PF04516.10 KND93065.1 - 2.5e-81 272.2 0.0 4.1e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 KND93065.1 - 0.069 11.6 0.1 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Tektin family Phage_G PF02306.10 KND93065.1 - 0.095 12.3 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Major spike protein (G protein) NACHT PF05729.7 KND93066.1 - 5.9e-07 29.3 0.1 1.7e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 KND93066.1 - 0.011 14.6 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KND93066.1 - 0.022 15.0 0.1 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KND93066.1 - 0.038 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KND93066.1 - 0.04 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KND93066.1 - 0.063 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KND93066.1 - 0.071 12.5 0.8 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KND93066.1 - 0.12 12.6 0.1 5.8 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KND93066.1 - 0.68 9.7 2.4 2.8 7.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 MFS_1 PF07690.11 KND93067.1 - 1.9e-33 115.6 34.2 1.9e-33 115.6 23.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93067.1 - 1.1e-08 34.1 9.4 1.1e-08 34.1 6.5 2.6 4 1 0 4 4 4 1 Sugar (and other) transporter DUF724 PF05266.9 KND93067.1 - 0.054 13.1 3.7 0.085 12.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Zn_clus PF00172.13 KND93071.1 - 6.1e-06 26.0 12.8 1e-05 25.3 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND93071.1 - 0.027 13.3 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KND93072.1 - 3.2e-82 274.7 47.5 2.1e-42 144.6 15.1 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KND93072.1 - 1.5e-36 125.7 0.0 3e-17 63.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KND93072.1 - 4.8e-35 119.3 2.4 5.4e-31 106.3 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KND93072.1 - 9e-17 60.9 0.0 2.1e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KND93072.1 - 3.2e-08 33.2 0.9 2.6e-05 23.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KND93072.1 - 3.6e-08 32.8 35.0 5.3e-06 25.7 11.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 KND93072.1 - 2.2e-07 30.8 0.2 0.0014 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KND93072.1 - 1.9e-06 27.1 0.1 0.0003 20.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND93072.1 - 2.3e-06 27.7 0.5 0.0049 16.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KND93072.1 - 1.8e-05 24.1 1.4 0.0074 15.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KND93072.1 - 4.4e-05 23.8 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KND93072.1 - 0.00016 21.1 0.6 0.011 15.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KND93072.1 - 0.00024 21.0 0.2 0.074 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND93072.1 - 0.00033 21.4 0.0 0.12 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KND93072.1 - 0.0011 18.2 0.0 0.45 9.7 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KND93072.1 - 0.0021 18.1 0.5 1.3 9.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KND93072.1 - 0.004 16.8 0.8 1.3 8.6 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 KND93072.1 - 0.0054 16.7 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND93072.1 - 0.0068 16.1 2.1 3 7.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KND93072.1 - 0.041 14.0 0.1 8 6.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KND93072.1 - 0.043 13.3 0.2 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KND93072.1 - 0.13 11.7 1.4 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KND93072.1 - 0.16 12.4 0.0 26 5.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KND93072.1 - 0.19 12.0 0.0 0.66 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KND93072.1 - 0.24 10.9 0.9 16 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KND93072.1 - 0.26 11.2 0.0 24 4.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 KND93072.1 - 0.33 10.5 1.2 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ADK PF00406.17 KND93072.1 - 0.43 10.4 1.3 26 4.6 0.1 2.4 2 0 0 2 2 2 0 Adenylate kinase Evr1_Alr PF04777.8 KND93073.1 - 1.7e-30 104.7 0.1 1.3e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 Erv1 / Alr family TPP_enzyme_N PF02776.13 KND93074.1 - 1.9e-33 115.3 0.3 3.3e-33 114.5 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KND93074.1 - 6e-26 90.8 0.0 1.6e-25 89.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KND93074.1 - 1.9e-15 56.7 0.1 2.4e-14 53.1 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain THUMP PF02926.12 KND93074.1 - 4.8e-11 42.7 2.3 4.7e-10 39.5 1.1 2.7 2 1 0 2 2 2 1 THUMP domain Pkinase PF00069.20 KND93075.1 - 3.4e-54 183.7 0.0 4.7e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93075.1 - 3.1e-19 69.0 0.0 4.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93075.1 - 0.00094 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND93075.1 - 0.0057 15.7 0.1 0.0088 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND93075.1 - 0.0096 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gag_p6 PF08705.6 KND93075.1 - 0.011 15.7 0.2 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 Seadorna_VP7 PF07387.6 KND93075.1 - 0.056 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.14 KND93075.1 - 0.057 12.7 0.4 0.14 11.4 0.2 1.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain HEM4 PF02602.10 KND93076.1 - 5.8e-31 107.5 0.0 9.4e-31 106.8 0.0 1.3 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Sec23_trunk PF04811.10 KND93078.1 - 1.3e-70 237.4 0.0 3.8e-70 236.0 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KND93078.1 - 4.5e-23 80.6 0.0 8.6e-22 76.5 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KND93078.1 - 4.4e-18 65.5 0.0 9.2e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KND93078.1 - 9.2e-18 63.5 5.3 1.5e-17 62.8 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KND93078.1 - 1e-08 34.7 0.2 2.8e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat DUF917 PF06032.7 KND93079.1 - 1.1e-110 369.4 0.0 1.7e-110 368.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KND93079.1 - 5.9e-48 163.4 11.5 3.9e-47 160.7 3.7 2.7 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KND93079.1 - 3.4e-24 85.2 6.8 8.7e-24 83.9 0.1 3.3 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 KND93079.1 - 0.037 12.9 2.3 0.93 8.3 0.1 3.3 4 0 0 4 4 4 0 StbA protein Zn_clus PF00172.13 KND93080.1 - 4.4e-06 26.4 11.4 4.4e-06 26.4 7.9 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc42p PF11544.3 KND93080.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p SGT1 PF07093.6 KND93082.1 - 4.9e-133 444.6 32.2 7.7e-132 440.6 22.3 2.0 1 1 0 1 1 1 1 SGT1 protein RRN3 PF05327.6 KND93082.1 - 9 4.2 8.9 14 3.6 6.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SNF2_N PF00176.18 KND93083.1 - 1.4e-71 240.7 0.1 2e-71 240.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND93083.1 - 5.2e-12 45.4 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 KND93083.1 - 1.1e-09 38.1 0.0 4.9e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 KND93083.1 - 7.7e-09 35.2 10.5 7.7e-09 35.2 7.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND93083.1 - 7.8e-09 35.0 11.7 1e-07 31.5 6.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND93083.1 - 4.7e-08 32.9 12.8 4.7e-08 32.9 8.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND93083.1 - 1.3e-07 31.2 11.0 1.3e-07 31.2 7.7 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND93083.1 - 4.4e-07 29.4 13.7 4.4e-07 29.4 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KND93083.1 - 8.5e-05 22.1 0.0 0.00021 20.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 KND93083.1 - 0.0015 18.3 11.4 0.0015 18.3 7.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND93083.1 - 0.0019 17.8 8.0 0.0019 17.8 5.6 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 KND93083.1 - 0.0034 17.4 9.0 0.0093 16.0 6.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KND93083.1 - 0.0041 16.8 5.3 0.012 15.4 3.6 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KND93083.1 - 0.008 16.0 2.7 0.018 14.8 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 KND93083.1 - 0.93 9.0 6.7 5.5 6.5 4.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-Nse PF11789.3 KND93083.1 - 6.2 6.4 9.0 23 4.5 6.2 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit NCA2 PF08637.5 KND93084.1 - 7.9e-84 280.9 0.0 1.3e-83 280.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 KND93085.1 - 1.2e-14 54.6 13.0 1.2e-14 54.6 9.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CDO_I PF05995.7 KND93086.1 - 1.9e-39 134.6 0.0 2.3e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KND93086.1 - 0.005 16.2 0.2 0.0086 15.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) SLAC1 PF03595.12 KND93087.1 - 1.1e-77 260.9 44.9 4.3e-63 212.9 22.6 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel Aminotran_1_2 PF00155.16 KND93092.1 - 3.8e-61 207.0 0.0 4.7e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KND93092.1 - 0.051 12.2 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Allinase Glyco_hydro_76 PF03663.9 KND93093.1 - 2.9e-130 434.9 6.8 4e-130 434.4 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KND93093.1 - 0.00034 19.7 5.1 0.36 9.8 0.1 3.2 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KND93093.1 - 0.029 12.6 0.4 0.85 7.8 0.0 2.3 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Internalin_N PF12354.3 KND93095.1 - 0.28 10.8 0.7 0.6 9.7 0.5 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Nrap PF03813.9 KND93096.1 - 0 1016.3 0.0 0 1016.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein I-set PF07679.11 KND93097.1 - 6.1e-06 25.9 0.3 0.49 10.2 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.6 KND93097.1 - 0.00019 20.7 2.4 5.8 6.3 0.0 5.2 5 0 0 5 5 5 3 Domain of unknown function (DUF1918) SseB PF07179.7 KND93097.1 - 0.073 12.8 0.2 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 SseB protein N-terminal domain Peptidase_C12 PF01088.16 KND93098.1 - 2.1e-40 138.2 1.7 1.3e-39 135.5 0.0 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2877 PF11392.3 KND93098.1 - 0.094 12.9 0.9 6.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Transglut_core2 PF13369.1 KND93099.1 - 2e-17 63.0 0.0 3.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KND93099.1 - 1.5e-06 27.8 1.2 3.7e-06 26.5 0.8 1.7 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 KND93099.1 - 9.9e-06 25.4 0.0 3.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 KND93099.1 - 2.1e-05 24.0 1.0 4e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_C14 PF00656.17 KND93100.1 - 5.1e-74 249.0 0.0 6.8e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Microtub_assoc PF07989.6 KND93103.1 - 4.1e-28 97.0 3.0 4.1e-28 97.0 2.0 12.4 9 2 5 14 14 14 2 Microtubule associated AAA_13 PF13166.1 KND93103.1 - 9.7e-06 24.3 28.0 9.7e-06 24.3 19.4 5.6 1 1 3 5 5 5 3 AAA domain HALZ PF02183.13 KND93103.1 - 0.00029 20.5 5.6 0.00029 20.5 3.8 11.6 11 1 2 13 13 13 1 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 KND93103.1 - 0.0036 17.1 1.3 0.0036 17.1 0.9 12.8 5 3 8 13 13 13 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KND93103.1 - 0.0045 16.7 22.7 0.0045 16.7 15.7 11.7 2 2 7 10 10 10 5 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.4 KND93103.1 - 0.0083 15.9 3.1 0.0083 15.9 2.1 12.5 4 4 7 13 13 13 2 Axonemal dynein light chain Myosin_tail_1 PF01576.14 KND93103.1 - 0.022 12.5 203.7 0.0021 15.8 26.9 5.2 2 1 1 4 4 4 0 Myosin tail Reo_sigmaC PF04582.7 KND93103.1 - 0.97 8.5 62.9 0.17 11.0 3.4 8.0 3 3 3 8 8 8 0 Reovirus sigma C capsid protein Acetyltransf_1 PF00583.19 KND93104.1 - 4.2e-06 26.6 0.1 1.2e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND93104.1 - 5.4e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND93104.1 - 0.071 13.2 0.0 0.098 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND93104.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND93104.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FMO-like PF00743.14 KND93105.1 - 5.1e-47 160.2 0.0 1.4e-37 129.0 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND93105.1 - 1.5e-18 67.6 0.0 3e-15 56.8 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RNase_T PF00929.19 KND93105.1 - 8.7e-11 42.3 0.0 1.6e-08 35.0 0.0 2.3 1 1 0 1 1 1 1 Exonuclease NAD_binding_9 PF13454.1 KND93105.1 - 6.9e-08 32.4 0.1 0.00097 18.9 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND93105.1 - 7.2e-08 32.5 0.0 9.6e-06 25.6 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND93105.1 - 5.5e-07 28.8 0.0 1.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KND93105.1 - 4e-06 25.9 0.0 0.38 9.5 0.0 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND93105.1 - 0.015 15.2 0.0 0.047 13.7 0.0 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KND93105.1 - 0.17 12.1 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding APH PF01636.18 KND93106.1 - 0.0046 16.7 0.4 0.0056 16.4 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Profilin PF00235.14 KND93107.1 - 2.5e-36 124.4 0.6 3.1e-36 124.1 0.4 1.1 1 0 0 1 1 1 1 Profilin Longin PF13774.1 KND93109.1 - 2.4e-15 55.8 0.0 4.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KND93109.1 - 1.8e-14 53.0 0.8 2.7e-14 52.5 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Gb3_synth PF04572.7 KND93109.1 - 0.021 14.5 0.1 0.078 12.6 0.0 2.0 3 0 0 3 3 3 0 Alpha 1,4-glycosyltransferase conserved region Tbf5 PF06331.7 KND93109.1 - 0.073 12.8 0.6 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Imm43 PF15602.1 KND93109.1 - 0.086 12.7 0.3 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 Sec63 PF02889.11 KND93110.1 - 5.1e-147 489.1 0.0 1.8e-95 319.8 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KND93110.1 - 3.3e-53 179.6 0.1 1.2e-27 96.5 0.2 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KND93110.1 - 1.5e-16 60.0 0.0 7.5e-07 28.9 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KND93110.1 - 3.6e-16 59.5 0.0 1e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND93110.1 - 1.7e-08 34.6 0.2 0.001 19.1 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KND93110.1 - 3.4e-05 23.5 0.5 0.11 12.2 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA PF00004.24 KND93110.1 - 0.00034 20.8 0.1 1.5 9.0 0.0 4.3 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KND93110.1 - 0.0075 15.7 0.1 14 5.0 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_10 PF12846.2 KND93110.1 - 0.03 13.7 0.0 11 5.3 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain Actin PF00022.14 KND93111.1 - 2.6e-55 187.4 0.0 9.5e-32 109.8 0.0 2.2 2 0 0 2 2 2 2 Actin OmpH PF03938.9 KND93111.1 - 0.0071 16.2 3.2 0.0071 16.2 2.2 3.4 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) DASH_Dad4 PF08650.5 KND93112.1 - 2.1e-17 62.7 2.4 2.9e-17 62.3 1.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 YL1_C PF08265.6 KND93113.1 - 5.8e-16 57.7 0.0 9.4e-16 57.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pterin_4a PF01329.14 KND93114.1 - 3.2e-28 97.3 0.1 4.1e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.16 KND93115.1 - 1.4e-06 28.1 9.3 1.4e-06 28.1 6.5 2.4 2 1 0 2 2 2 1 bZIP transcription factor Leu_zip PF15294.1 KND93115.1 - 0.003 16.7 0.1 0.003 16.7 0.1 1.8 2 0 0 2 2 2 1 Leucine zipper DUF972 PF06156.8 KND93115.1 - 0.11 12.8 1.9 0.58 10.5 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Adeno_PIX PF03955.9 KND93115.1 - 0.13 12.7 0.3 0.13 12.7 0.2 2.7 3 1 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Ribosomal_L30_N PF08079.7 KND93115.1 - 0.96 9.5 10.0 2.2 8.3 6.9 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain bZIP_2 PF07716.10 KND93115.1 - 3.4 7.5 18.2 0.71 9.7 0.2 3.0 2 1 1 3 3 3 0 Basic region leucine zipper MFS_1 PF07690.11 KND93116.1 - 1e-23 83.6 40.1 1.4e-16 60.1 17.2 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily HIT PF01230.18 KND93116.1 - 2.8e-17 63.0 0.0 5.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 HIT domain PUCC PF03209.10 KND93116.1 - 0.00048 18.9 7.4 0.015 14.0 4.1 2.3 2 0 0 2 2 2 2 PUCC protein Tropomyosin_1 PF12718.2 KND93117.1 - 0.0051 16.6 1.4 0.0061 16.4 1.0 1.2 1 0 0 1 1 1 1 Tropomyosin like PspA_IM30 PF04012.7 KND93117.1 - 0.056 12.7 1.8 0.11 11.8 1.3 1.5 1 1 0 1 1 1 0 PspA/IM30 family DUF2959 PF11172.3 KND93117.1 - 0.065 12.9 0.3 0.088 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) HisKA_3 PF07730.8 KND93117.1 - 0.074 13.3 1.5 9.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase Seryl_tRNA_N PF02403.17 KND93117.1 - 0.085 12.8 0.7 0.14 12.2 0.5 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HalX PF08663.5 KND93117.1 - 0.12 12.3 3.8 2.9 7.9 2.1 2.6 2 1 0 2 2 2 0 HalX domain Zwint PF15556.1 KND93117.1 - 0.14 11.4 1.7 0.22 10.7 1.2 1.2 1 1 0 1 1 1 0 ZW10 interactor IncA PF04156.9 KND93117.1 - 0.2 11.2 0.9 0.25 10.9 0.6 1.2 1 0 0 1 1 1 0 IncA protein YscO PF07321.7 KND93117.1 - 0.3 10.9 4.0 10 5.9 0.1 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO Lebercilin PF15619.1 KND93117.1 - 0.57 9.5 4.0 4.9 6.5 0.3 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Myb_Cef PF11831.3 KND93118.1 - 5e-61 205.8 7.8 5e-61 205.8 5.4 3.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KND93118.1 - 8e-20 70.6 4.6 2.6e-09 36.9 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND93118.1 - 5.9e-19 67.9 10.6 5e-15 55.3 2.3 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain DcpS_C PF11969.3 KND93119.1 - 6.9e-32 110.1 0.0 1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KND93119.1 - 2.4e-23 82.6 0.0 3.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal MFS_1 PF07690.11 KND93120.1 - 1e-40 139.5 47.0 1e-40 139.5 32.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93120.1 - 1.5e-11 43.5 13.3 1.5e-11 43.5 9.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KND93120.1 - 3.9e-05 22.2 10.5 3.9e-05 22.2 7.3 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein SH3_9 PF14604.1 KND93121.1 - 7.9e-07 28.5 0.2 1.5e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.13 KND93121.1 - 9.1e-05 22.2 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A SH3_1 PF00018.23 KND93121.1 - 0.00029 20.1 0.4 0.00057 19.2 0.3 1.5 1 0 0 1 1 1 1 SH3 domain Mid2 PF04478.7 KND93121.1 - 0.00071 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor GILT PF03227.11 KND93122.1 - 1.3e-13 50.7 0.6 2.2e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Got1 PF04178.7 KND93123.1 - 1.3e-17 63.9 13.4 1.6e-17 63.7 9.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KND93123.1 - 0.63 9.7 12.5 0.065 12.8 3.0 2.4 2 0 0 2 2 2 0 YrhK-like protein End3 PF12761.2 KND93124.1 - 1.1e-71 240.5 2.4 1.5e-71 240.1 1.7 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KND93124.1 - 2.3e-46 155.8 0.0 7.1e-46 154.2 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KND93124.1 - 7.6e-06 24.8 0.1 1.7e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KND93124.1 - 3.8e-05 23.1 0.1 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KND93124.1 - 0.00011 22.2 0.0 0.00045 20.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KND93124.1 - 0.0049 16.6 0.2 0.037 13.8 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KND93124.1 - 0.0055 16.0 0.2 0.017 14.4 0.2 1.8 1 0 0 1 1 1 1 EF hand NPV_P10 PF05531.7 KND93124.1 - 0.099 12.9 0.4 13 6.1 0.2 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein NUDIX PF00293.23 KND93125.1 - 4e-28 97.7 0.0 6.3e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 KND93126.1 - 2.5e-09 37.1 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND93126.1 - 7e-08 32.3 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KND93126.1 - 3.9e-05 23.4 0.1 8.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND93126.1 - 0.00038 20.1 0.0 0.00078 19.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KND93126.1 - 0.0015 18.6 0.6 0.005 16.9 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND93126.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RPA_C PF08784.6 KND93127.1 - 1.8e-20 73.2 0.4 4e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KND93127.1 - 2e-09 37.1 0.1 4.8e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Zn_clus PF00172.13 KND93128.1 - 0.39 10.6 5.7 0.33 10.8 0.6 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.14 KND93129.1 - 7.5e-35 118.9 0.1 1.2e-34 118.3 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KND93129.1 - 1.3e-13 50.8 0.0 2.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KND93129.1 - 7.9e-10 38.4 0.0 2.1e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FHA PF00498.21 KND93130.1 - 2e-09 37.4 0.3 2.8e-09 36.9 0.2 1.3 1 1 0 1 1 1 1 FHA domain Pkinase PF00069.20 KND93131.1 - 2.2e-15 56.5 0.0 3.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93131.1 - 2.4e-05 23.5 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C2H2_jaz PF12171.3 KND93132.1 - 1.5e-10 40.9 26.5 7.4e-05 22.7 2.3 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND93132.1 - 1.6e-09 37.6 22.6 0.0058 16.7 1.6 6.1 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KND93132.1 - 1.3e-08 34.5 29.9 0.023 15.0 0.1 7.3 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KND93132.1 - 1.8e-08 34.2 37.3 0.0021 18.3 0.2 7.5 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KND93132.1 - 9.5e-08 32.0 22.4 0.087 12.9 0.6 6.3 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KND93132.1 - 3.8e-06 26.8 30.7 0.23 11.8 0.3 6.7 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 KND93132.1 - 0.00017 21.3 28.5 0.25 11.2 0.1 7.0 7 0 0 7 7 7 2 C2H2-type zinc finger Trm112p PF03966.11 KND93132.1 - 0.014 15.7 3.8 6 7.3 0.0 3.6 2 1 0 2 2 2 0 Trm112p-like protein zf-Di19 PF05605.7 KND93132.1 - 0.016 15.3 0.0 0.016 15.3 0.0 5.0 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.6 KND93132.1 - 0.071 12.8 5.5 0.46 10.2 0.3 2.8 3 1 1 4 4 4 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.9 KND93132.1 - 0.072 12.5 1.9 6.9 6.2 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.1 KND93132.1 - 0.1 12.2 12.5 1.2 8.9 0.5 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF164 PF02591.10 KND93132.1 - 0.92 9.3 4.6 4.2 7.2 0.0 3.8 4 0 0 4 4 4 0 Putative zinc ribbon domain DUF1033 PF06279.6 KND93132.1 - 1.1 9.1 4.5 1.2 8.9 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) HypA PF01155.14 KND93132.1 - 4.1 7.1 10.6 1 9.0 0.7 3.5 2 2 1 3 3 3 0 Hydrogenase expression/synthesis hypA family MIP-T3 PF10243.4 KND93134.1 - 0.043 12.3 66.4 0.061 11.7 46.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pkinase PF00069.20 KND93135.1 - 2.5e-18 66.1 0.0 5.1e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND93135.1 - 3.4e-06 26.3 0.0 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KND93135.1 - 0.041 12.8 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like EB1 PF03271.12 KND93136.1 - 1e-16 60.6 1.8 2.1e-16 59.6 1.3 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KND93136.1 - 3e-07 30.4 1.3 4.3e-07 29.9 0.6 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Syja_N PF02383.13 KND93136.1 - 0.032 13.0 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Suppressor_APC PF11414.3 KND93136.1 - 0.087 12.6 0.6 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Phi-29_GP3 PF05435.6 KND93136.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 PX PF00787.19 KND93137.1 - 5.6e-14 51.8 0.0 9.3e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KND93137.1 - 5.6e-12 45.1 8.9 6.3e-12 45.0 5.1 2.0 3 0 0 3 3 3 1 SNARE domain adh_short PF00106.20 KND93138.1 - 5e-30 104.6 1.3 6.5e-30 104.2 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND93138.1 - 7e-25 88.1 0.0 9.2e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND93138.1 - 5.5e-14 52.2 0.9 2e-13 50.3 0.7 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND93138.1 - 4.6e-07 29.5 0.2 2.6e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND93138.1 - 0.00024 21.1 0.3 0.00089 19.3 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KND93138.1 - 0.034 13.9 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KND93138.1 - 0.064 12.1 0.1 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain AdoHcyase_NAD PF00670.16 KND93138.1 - 0.089 12.6 0.8 0.22 11.3 0.6 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_trans_4_4 PF13579.1 KND93138.1 - 0.097 12.8 0.3 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DEAD PF00270.24 KND93139.1 - 1.4e-45 154.8 0.0 2.7e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.4 KND93139.1 - 1.2e-31 108.5 0.0 3.3e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.26 KND93139.1 - 2.2e-24 85.0 0.0 4.7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KND93139.1 - 0.0081 14.6 1.0 0.02 13.3 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Lon_C PF05362.8 KND93140.1 - 1.4e-66 223.7 0.6 2.7e-66 222.7 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KND93140.1 - 3.8e-24 85.4 0.0 7e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KND93140.1 - 1.1e-22 80.6 0.0 2.8e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND93140.1 - 1.7e-08 34.2 0.0 4.7e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KND93140.1 - 1e-06 28.2 0.1 5.3e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KND93140.1 - 2.3e-06 27.7 0.0 6.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KND93140.1 - 1e-05 25.5 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.6 KND93140.1 - 1.2e-05 24.8 0.0 4.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND93140.1 - 5.5e-05 23.9 0.0 0.00017 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KND93140.1 - 0.00018 21.0 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KND93140.1 - 0.00021 20.4 0.3 0.0012 17.9 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KND93140.1 - 0.00034 20.7 0.0 0.0047 17.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KND93140.1 - 0.0011 17.7 0.3 0.0076 15.0 0.1 2.2 2 1 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 KND93140.1 - 0.0015 18.2 0.1 0.0068 16.1 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 KND93140.1 - 0.0021 17.9 0.1 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KND93140.1 - 0.0071 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND93140.1 - 0.0074 15.7 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND93140.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KND93140.1 - 0.015 14.9 0.1 0.059 13.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KND93140.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KND93140.1 - 0.023 15.0 1.3 0.14 12.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KND93140.1 - 0.025 14.7 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KND93140.1 - 0.03 14.6 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KND93140.1 - 0.036 12.9 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 KND93140.1 - 0.052 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 KND93140.1 - 0.055 12.6 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 KND93140.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KND93140.1 - 0.1 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Daxx PF03344.10 KND93142.1 - 0.29 9.5 6.4 0.5 8.8 4.4 1.3 1 0 0 1 1 1 0 Daxx Family Arm PF00514.18 KND93142.1 - 1.5 8.7 8.2 3.2 7.7 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3112 PF11309.3 KND93144.1 - 3.3e-44 150.5 15.5 1.6e-41 141.7 2.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Metallophos PF00149.23 KND93145.1 - 2e-40 138.3 1.5 2.5e-40 138.0 1.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Radical_SAM PF04055.16 KND93146.1 - 2.6e-26 92.7 0.1 7.9e-26 91.1 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 KND93146.1 - 1.7e-23 82.4 0.1 3.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 KND93146.1 - 2.9e-08 33.8 0.2 2.1e-07 31.0 0.1 2.5 2 0 0 2 2 2 1 Flavodoxin Vps51 PF08700.6 KND93147.1 - 2.8e-12 46.3 0.2 2.8e-12 46.3 0.2 2.1 3 0 0 3 3 3 1 Vps51/Vps67 Laminin_B PF00052.13 KND93147.1 - 0.0054 16.3 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF2383 PF09537.5 KND93147.1 - 0.016 15.4 3.3 0.071 13.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Atg14 PF10186.4 KND93147.1 - 5.8 5.7 12.2 2.2 7.1 0.6 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MAS20 PF02064.10 KND93148.1 - 3.9e-09 36.4 3.9 4.4e-07 29.8 3.2 2.6 2 1 0 2 2 2 1 MAS20 protein import receptor Orbi_VP6 PF01516.11 KND93148.1 - 0.0029 16.7 0.3 0.0042 16.1 0.2 1.1 1 0 0 1 1 1 1 Orbivirus helicase VP6 Rhabdo_ncap PF00945.13 KND93148.1 - 0.067 11.7 0.6 0.089 11.3 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Glyco_hydro_47 PF01532.15 KND93149.1 - 7.3e-158 525.9 0.0 9.1e-158 525.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 KND93150.1 - 1.6e-60 204.4 0.0 2.6e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93150.1 - 4.4e-44 150.4 0.0 6.9e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93150.1 - 2.2e-08 33.4 0.0 2.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND93150.1 - 0.0034 16.4 0.0 0.008 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Siah-Interact_N PF09032.6 KND93150.1 - 0.16 12.0 0.9 0.38 10.8 0.6 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal Mito_carr PF00153.22 KND93151.1 - 2.4e-55 184.2 5.4 3.9e-19 68.1 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.8 KND93152.1 - 5.6e-85 285.7 0.0 1.1e-84 284.8 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF4164 PF13747.1 KND93152.1 - 0.034 14.2 9.0 0.099 12.7 3.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) LRV PF01816.12 KND93152.1 - 0.048 13.8 0.2 0.25 11.5 0.2 2.3 1 0 0 1 1 1 0 Leucine rich repeat variant RasGAP_C PF03836.10 KND93152.1 - 0.053 13.2 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 RasGAP C-terminus ADIP PF11559.3 KND93152.1 - 0.12 12.2 4.9 0.33 10.8 3.4 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin_2 PF14523.1 KND93152.1 - 0.43 10.6 4.2 0.69 9.9 2.1 1.9 2 0 0 2 2 2 0 Syntaxin-like protein Reo_sigmaC PF04582.7 KND93152.1 - 0.53 9.4 2.6 1.1 8.3 1.8 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KND93152.1 - 0.57 9.9 8.3 0.15 11.8 1.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 KND93152.1 - 2.5 7.8 7.2 2.6 7.8 2.5 2.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 KND93152.1 - 3.1 7.6 6.9 76 3.1 4.0 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 KND93152.1 - 7.9 6.3 8.7 2 8.2 1.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GFA PF04828.9 KND93153.1 - 4e-13 49.1 8.2 4.2e-08 33.0 0.0 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KND93153.1 - 0.018 14.5 4.1 0.03 13.8 0.1 3.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PGC7_Stella PF15549.1 KND93153.1 - 0.091 12.7 0.8 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Rsm1 PF08600.5 KND93153.1 - 0.22 11.3 1.6 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Rsm1-like Nudix_N_2 PF14803.1 KND93153.1 - 0.23 11.1 0.2 0.23 11.1 0.1 3.5 3 0 0 3 3 3 0 Nudix N-terminal Cytochrome_CBB3 PF13442.1 KND93153.1 - 0.82 9.8 3.1 1.6 8.9 0.3 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III WD40 PF00400.27 KND93154.1 - 0.00055 19.7 1.6 0.051 13.4 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat GFO_IDH_MocA PF01408.17 KND93156.1 - 6.1e-10 39.6 0.0 6.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fructosamin_kin PF03881.9 KND93158.1 - 6.2e-08 31.9 0.0 7e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase CoA_binding_2 PF13380.1 KND93159.1 - 5.4e-20 71.6 0.1 2.1e-18 66.5 0.1 2.0 1 1 0 1 1 1 1 CoA binding domain CIMR PF00878.13 KND93161.1 - 5.7e-07 29.3 0.1 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 KND93161.1 - 0.0084 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Myb_DNA-bind_4 PF13837.1 KND93162.1 - 0.00031 20.8 0.1 0.00057 19.9 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Scs3p PF10261.4 KND93163.1 - 7.2e-64 215.0 3.0 9.7e-64 214.6 2.1 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.4 KND93163.1 - 6.5e-16 57.8 0.0 1.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Ank PF00023.25 KND93164.1 - 2.5e-09 36.4 0.1 8.2e-05 22.2 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeat AAA_16 PF13191.1 KND93164.1 - 4.6e-07 29.9 0.1 2.4e-06 27.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Ank_2 PF12796.2 KND93164.1 - 1.1e-06 28.8 0.1 0.033 14.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) NACHT PF05729.7 KND93164.1 - 1.8e-05 24.4 0.0 5.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 KND93164.1 - 4.3e-05 23.9 0.1 0.11 13.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93164.1 - 8.8e-05 22.3 0.1 0.74 10.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat AAA_22 PF13401.1 KND93164.1 - 0.00015 21.9 0.1 0.00049 20.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KND93164.1 - 0.0059 16.7 0.1 0.05 13.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.1 KND93164.1 - 0.0068 16.6 0.0 1.4 9.3 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) AAA_10 PF12846.2 KND93164.1 - 0.084 12.3 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain Glyco_hydro_3 PF00933.16 KND93167.1 - 1.8e-89 299.6 0.0 2.7e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND93167.1 - 1.7e-49 168.3 0.2 3.5e-49 167.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND93167.1 - 3.8e-17 61.9 0.3 8.4e-17 60.8 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.12 KND93168.1 - 6.4e-163 542.2 0.6 7.3e-163 542.0 0.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ist1 PF03398.9 KND93169.1 - 7.3e-64 214.1 0.7 9.1e-64 213.8 0.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway eIF3g PF12353.3 KND93170.1 - 0.54 10.1 10.0 2 8.3 0.9 2.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 KND93170.1 - 5.5 6.7 9.1 13 5.5 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle PDZ_1 PF12812.2 KND93172.1 - 1e-58 195.1 0.1 2.4e-36 123.4 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 KND93172.1 - 9.7e-15 54.2 0.1 1.2e-06 28.2 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 KND93172.1 - 1.4e-13 50.9 0.3 6.1e-12 45.5 0.1 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 KND93172.1 - 1.4e-09 37.9 0.0 0.00022 21.3 0.0 4.0 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KND93172.1 - 0.0017 18.1 0.9 0.092 12.5 0.1 3.4 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.21 KND93172.1 - 0.0079 15.7 0.5 0.052 13.1 0.3 2.2 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.4 KND93172.1 - 0.091 11.1 0.2 0.85 7.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.16 KND93172.1 - 0.17 11.2 0.3 0.41 10.0 0.2 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease CUE PF02845.11 KND93173.1 - 1e-10 40.9 0.0 1.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 CUE domain GCR1_C PF12550.3 KND93173.1 - 0.045 13.6 0.8 0.074 12.9 0.1 1.7 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes DUF2768 PF10966.3 KND93173.1 - 0.57 10.3 2.9 0.67 10.1 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) DnaJ PF00226.26 KND93174.1 - 9.6e-21 73.2 0.6 1.9e-20 72.3 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.14 KND93175.1 - 1.8e-42 144.8 0.3 2.3e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KND93175.1 - 0.00024 21.4 0.1 0.00044 20.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KND93175.1 - 0.0036 16.1 1.6 1.1 7.9 0.0 2.8 3 0 0 3 3 3 2 ArgK protein GTP_EFTU PF00009.22 KND93175.1 - 0.0068 15.8 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain CobW_C PF07683.9 KND93175.1 - 0.0085 15.7 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_19 PF13245.1 KND93175.1 - 0.011 15.4 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 KND93175.1 - 0.013 15.9 0.2 0.53 10.7 0.1 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KND93175.1 - 0.016 14.7 0.2 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KND93175.1 - 0.034 13.6 0.5 0.097 12.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KND93175.1 - 0.035 13.6 0.8 2.7 7.4 0.2 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KND93175.1 - 0.041 13.0 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KND93175.1 - 0.048 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KND93175.1 - 0.054 13.6 0.3 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KND93175.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 KND93175.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND93175.1 - 0.097 12.6 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KND93175.1 - 0.1 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KND93175.1 - 0.1 12.8 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND93175.1 - 0.13 12.6 0.1 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 KND93175.1 - 0.16 11.9 2.9 0.13 12.2 0.5 2.2 2 1 0 2 2 1 0 50S ribosome-binding GTPase NOT2_3_5 PF04153.13 KND93176.1 - 1.8e-33 115.2 2.3 3e-33 114.5 1.6 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Fungal_trans_2 PF11951.3 KND93177.1 - 5.7e-11 41.6 0.1 1.7e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mob1_phocein PF03637.12 KND93178.1 - 9.3e-28 97.0 0.2 1.4e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Ank PF00023.25 KND93179.1 - 7.6e-17 60.1 0.1 1.4e-11 43.6 0.2 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KND93179.1 - 1.1e-16 60.7 0.3 3.2e-08 33.8 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND93179.1 - 1.2e-16 60.8 0.0 1.8e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND93179.1 - 2.1e-14 53.1 0.6 2.6e-11 43.3 0.1 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93179.1 - 5.9e-12 44.6 0.0 1.9e-08 33.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat XFP_N PF09364.5 KND93180.1 - 2.1e-173 576.1 0.0 2.8e-173 575.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KND93180.1 - 1.5e-81 272.2 0.0 3e-81 271.2 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KND93180.1 - 5e-80 267.7 0.0 7.1e-80 267.2 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain E1_dh PF00676.15 KND93180.1 - 0.2 10.3 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Ribosomal_S2 PF00318.15 KND93181.1 - 7.5e-48 162.5 0.0 1.8e-47 161.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 KND93181.1 - 2.3e-37 126.5 10.3 4.1e-10 39.3 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KND93181.1 - 4.6e-07 29.4 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 PB1 domain FAM176 PF14851.1 KND93181.1 - 0.17 11.5 1.4 0.67 9.6 0.9 2.0 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 KND93181.1 - 5 7.5 13.7 0.055 13.7 3.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-H2C2 PF09337.5 KND93182.1 - 1.4e-20 72.4 4.1 2.9e-20 71.3 2.9 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KND93182.1 - 0.00021 21.2 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KND93182.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND93182.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.19 KND93183.1 - 2e-141 471.9 4.9 2.3e-141 471.7 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 KND93185.1 - 3.4e-49 166.5 0.0 1.2e-48 164.8 0.0 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DUF1963 PF09234.5 KND93185.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1963) Cpn60_TCP1 PF00118.19 KND93186.1 - 7.4e-147 489.8 0.3 8.4e-147 489.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4470 PF14737.1 KND93187.1 - 1.1e-11 44.3 0.8 5.4e-09 35.6 0.6 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KND93187.1 - 1.3e-10 41.0 15.7 2.7e-10 39.9 10.8 1.6 1 0 0 1 1 1 1 MYND finger zf-C2H2 PF00096.21 KND93188.1 - 9e-10 38.3 19.5 0.00041 20.5 4.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND93188.1 - 2.4e-08 33.8 12.6 0.00023 21.2 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND93188.1 - 0.008 16.4 17.4 0.65 10.4 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-LYAR PF08790.6 KND93188.1 - 3.7 7.3 7.8 0.26 11.0 0.2 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.1 KND93188.1 - 6.9 6.7 10.7 0.88 9.5 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger MOSC_N PF03476.11 KND93189.1 - 9.3e-11 41.4 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KND93189.1 - 9.2e-09 34.8 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain SHR3_chaperone PF08229.6 KND93189.1 - 0.23 10.4 0.7 0.35 9.8 0.5 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 SMC_N PF02463.14 KND93190.1 - 1.6e-67 226.9 8.5 3.1e-36 124.6 0.4 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KND93190.1 - 5e-22 78.1 3.5 5.1e-22 78.0 0.3 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KND93190.1 - 5.6e-12 46.2 3.4 2.7e-05 24.3 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KND93190.1 - 2.4e-08 34.5 19.0 2.4e-08 34.5 13.2 6.4 2 2 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 KND93190.1 - 8.8e-05 21.8 31.9 0.0035 16.5 0.6 5.7 3 2 3 6 6 6 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 KND93190.1 - 0.00088 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain COG2 PF06148.6 KND93190.1 - 0.0024 17.7 2.4 0.0024 17.7 1.7 7.9 5 2 4 9 9 9 2 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.22 KND93190.1 - 8.1 6.7 27.4 1.3 9.2 0.0 5.7 3 2 0 3 3 3 0 ABC transporter WD40 PF00400.27 KND93191.1 - 2.8e-27 93.5 16.4 1.3e-08 34.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3639 PF12341.3 KND93191.1 - 0.1 12.6 0.0 0.36 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) DUF1014 PF06244.7 KND93192.1 - 1.2e-21 77.1 5.6 4.6e-21 75.2 3.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) UCR_TM PF02921.9 KND93193.1 - 3.6e-20 71.9 0.4 3.6e-20 71.9 0.3 1.7 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KND93193.1 - 2e-17 62.5 0.0 3.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain AA_permease PF00324.16 KND93193.1 - 0.11 10.8 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease MMS1_N PF10433.4 KND93194.1 - 9.5e-80 268.1 0.0 1.6e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KND93194.1 - 8.3e-61 205.8 0.0 2.6e-60 204.2 0.0 1.9 1 0 0 1 1 1 1 CPSF A subunit region Beta_propel PF09826.4 KND93194.1 - 0.057 11.7 0.0 0.098 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta propeller domain Peptidase_C1 PF00112.18 KND93195.1 - 0.00054 19.9 0.4 0.0015 18.4 0.1 1.7 2 0 0 2 2 2 1 Papain family cysteine protease PQ-loop PF04193.9 KND93196.1 - 2.8e-22 78.0 15.4 3e-13 49.0 0.4 3.0 3 1 0 3 3 3 2 PQ loop repeat DUF4131 PF13567.1 KND93196.1 - 0.04 13.3 0.5 0.04 13.3 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF3796 PF12676.2 KND93196.1 - 0.12 12.6 1.5 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) R3H-assoc PF13902.1 KND93198.1 - 3.3e-20 72.3 3.3 3.3e-20 72.3 2.3 1.6 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 KND93198.1 - 0.039 13.6 0.5 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 R3H domain DUF605 PF04652.11 KND93199.1 - 1.6 8.0 11.9 2.2 7.5 8.3 1.1 1 0 0 1 1 1 0 Vta1 like PRCC PF10253.4 KND93199.1 - 6.4 7.4 9.7 12 6.5 6.8 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.4 KND93199.1 - 7.3 5.1 17.1 9.5 4.7 11.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FA_desaturase PF00487.19 KND93200.1 - 2.6e-17 63.1 10.3 2.6e-17 63.1 7.2 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KND93200.1 - 6.1e-17 61.1 0.4 2.2e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 KND93201.1 - 0.0027 17.5 13.2 6.9 6.7 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Shadoo PF14999.1 KND93201.1 - 4 7.3 10.0 1.6 8.6 0.0 3.4 3 1 1 4 4 4 0 Shadow of prion protein, neuroprotective SKG6 PF08693.5 KND93202.1 - 0.026 13.8 0.1 0.058 12.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 KND93202.1 - 0.1 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GTP_EFTU PF00009.22 KND93203.1 - 3e-48 163.7 0.0 5.3e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KND93203.1 - 1.2e-19 69.9 0.0 2.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KND93203.1 - 4.2e-14 52.1 0.0 6.1e-13 48.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND93203.1 - 0.00022 21.2 0.0 0.00058 19.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 COPI_assoc PF08507.5 KND93204.1 - 2.6e-31 108.1 4.5 3.4e-31 107.7 3.1 1.1 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KND93204.1 - 0.64 10.0 8.2 1.8 8.5 5.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P UCR_Fe-S_N PF10399.4 KND93204.1 - 5.1 6.3 5.3 0.49 9.6 0.1 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3784 PF12650.2 KND93204.1 - 9.4 6.2 8.4 0.73 9.8 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) NMD3 PF04981.8 KND93205.1 - 1.6e-69 233.6 4.0 2.6e-69 232.9 2.8 1.3 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KND93205.1 - 0.039 13.8 0.7 0.67 9.9 0.1 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 KND93205.1 - 0.39 10.5 8.7 12 5.7 3.6 2.8 2 1 0 2 2 2 0 Double zinc ribbon AF1Q PF15017.1 KND93205.1 - 4.6 7.2 6.7 14 5.6 0.0 3.2 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator RRM_6 PF14259.1 KND93206.1 - 5.4e-06 26.3 0.0 2.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND93206.1 - 7.7e-06 25.4 0.0 0.0013 18.2 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND93206.1 - 0.031 14.1 0.0 0.49 10.2 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 KND93206.1 - 0.089 11.6 0.5 0.15 10.9 0.4 1.3 1 0 0 1 1 1 0 AAR2 protein Nop14 PF04147.7 KND93206.1 - 1 7.2 21.9 0.0057 14.6 6.4 2.0 2 0 0 2 2 2 0 Nop14-like family Aldedh PF00171.17 KND93207.1 - 1.3e-134 448.9 0.0 1.5e-134 448.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KND93207.1 - 2.1e-05 23.4 0.0 4e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) CN_hydrolase PF00795.17 KND93209.1 - 4.1e-18 65.3 0.0 6.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KND93209.1 - 3.5e-15 55.5 0.2 1.7e-14 53.3 0.1 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KND93209.1 - 0.02 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Syntaxin-18_N PF10496.4 KND93210.1 - 5e-13 48.6 0.0 1.8e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KND93210.1 - 0.34 10.6 4.1 0.3 10.8 0.3 2.9 3 1 1 4 4 4 0 SNARE domain Aminotran_1_2 PF00155.16 KND93211.1 - 6.5e-82 275.3 0.0 8.3e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2365 PF10157.4 KND93213.1 - 0.016 15.1 0.0 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) USP8_dimer PF08969.6 KND93213.1 - 0.045 13.7 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 USP8 dimerisation domain DUF2505 PF10698.4 KND93213.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Methyltransf_18 PF12847.2 KND93215.1 - 1.3e-10 41.8 0.0 3.3e-10 40.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND93215.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND93215.1 - 6.1e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND93215.1 - 0.00013 22.2 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KND93215.1 - 0.00021 20.9 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KND93215.1 - 0.00048 20.5 0.0 0.0021 18.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 KND93215.1 - 0.0021 17.6 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.7 KND93215.1 - 0.0073 15.6 0.0 0.067 12.5 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW CMAS PF02353.15 KND93215.1 - 0.01 14.9 0.0 0.026 13.6 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KND93215.1 - 0.015 15.3 0.6 0.044 13.8 0.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 KND93215.1 - 0.021 15.6 0.0 0.077 13.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KND93215.1 - 0.026 14.1 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KND93215.1 - 0.034 13.5 0.1 0.081 12.3 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase Amidase PF01425.16 KND93216.1 - 8.5e-89 298.4 0.2 1.5e-88 297.5 0.1 1.4 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 KND93216.1 - 1.7e-82 276.8 0.0 2.9e-82 276.0 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KND93216.1 - 1.1e-62 211.1 0.0 1.9e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KND93216.1 - 2.5e-36 125.0 0.0 5.1e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 KND93216.1 - 4.1e-34 116.9 0.1 8.8e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KND93216.1 - 1.2e-31 108.8 0.0 3.1e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KND93216.1 - 8e-15 55.0 0.0 2.6e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KND93216.1 - 4.2e-13 48.7 0.3 9.5e-13 47.6 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KND93216.1 - 5.5e-10 38.9 0.0 9.3e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KND93216.1 - 2.8e-09 36.4 0.0 0.00046 19.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 KND93216.1 - 4.4e-07 29.5 0.0 5.8e-05 22.5 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 KND93216.1 - 0.0002 20.9 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KND93216.1 - 0.00023 20.5 0.1 0.00076 18.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD_2 PF12700.2 KND93216.1 - 0.0021 17.3 0.0 0.66 9.0 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 KND93216.1 - 0.099 12.9 0.0 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein Fungal_trans PF04082.13 KND93217.1 - 2.6e-20 72.3 0.0 4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93217.1 - 3.9e-05 23.4 6.2 7.5e-05 22.5 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M3 PF01432.15 KND93220.1 - 9.7e-86 288.5 0.0 1.6e-85 287.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_S48 PF03574.10 KND93220.1 - 0.033 14.2 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S48 Pkinase_C PF00433.19 KND93221.1 - 0.0041 17.6 0.1 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Melibiase PF02065.13 KND93222.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Melibiase CAP59_mtransfer PF11735.3 KND93223.1 - 2.4e-64 216.8 0.0 3.2e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.17 KND93225.1 - 2e-49 168.3 0.0 3.6e-49 167.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 KND93226.1 - 5.5e-69 233.1 0.0 6.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy PF03171.15 KND93228.1 - 0.0027 17.9 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1235 PF06822.7 KND93228.1 - 0.0033 16.4 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1235) 2OG-FeII_Oxy_3 PF13640.1 KND93228.1 - 0.028 14.9 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ion_trans PF00520.26 KND93229.1 - 1.4e-06 27.7 16.5 1.4e-06 27.7 11.4 2.6 1 1 2 3 3 3 1 Ion transport protein PKD_channel PF08016.7 KND93229.1 - 0.00099 17.6 11.6 0.055 11.8 1.5 2.3 1 1 1 2 2 2 2 Polycystin cation channel DUF3814 PF12769.2 KND93229.1 - 0.03 14.4 0.4 0.084 13.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) SNARE PF05739.14 KND93229.1 - 0.037 13.7 0.7 0.071 12.8 0.5 1.4 1 0 0 1 1 1 0 SNARE domain SlyX PF04102.7 KND93229.1 - 0.066 13.5 0.3 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 SlyX p450 PF00067.17 KND93231.1 - 6.5e-33 113.9 0.0 1.1e-28 100.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF3494 PF11999.3 KND93232.1 - 2.2e-36 125.4 21.6 2.7e-36 125.1 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) APH PF01636.18 KND93233.1 - 4.1e-09 36.5 0.1 5.1e-08 32.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND93233.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase ACBP PF00887.14 KND93234.1 - 6.8e-20 70.5 0.6 1e-19 69.9 0.4 1.3 1 1 0 1 1 1 1 Acyl CoA binding protein PrkA PF06798.7 KND93234.1 - 0.086 12.1 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Bromodomain PF00439.20 KND93236.1 - 2.2e-18 65.9 0.0 7.3e-18 64.2 0.0 1.9 2 0 0 2 2 2 1 Bromodomain BTB PF00651.26 KND93236.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_L11 PF00298.14 KND93238.1 - 3.6e-25 87.8 0.6 2.2e-24 85.3 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KND93238.1 - 4.5e-25 86.8 0.1 7.6e-25 86.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain PLDc PF00614.17 KND93239.1 - 9.9e-14 50.6 1.2 1.4e-06 27.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KND93239.1 - 2e-12 46.9 0.1 6.2e-06 25.9 0.0 3.0 3 1 0 3 3 3 2 PLD-like domain RE_NgoFVII PF09565.5 KND93239.1 - 0.00067 18.7 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 NgoFVII restriction endonuclease Thioredoxin PF00085.15 KND93240.1 - 2.9e-44 148.9 3.0 1e-25 89.4 0.1 3.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KND93240.1 - 2.2e-12 47.1 0.0 6.1e-05 22.8 0.0 4.5 3 1 2 5 5 5 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND93240.1 - 3.7e-10 39.7 2.8 7.3e-05 22.8 0.0 5.0 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KND93240.1 - 1.6e-07 31.2 0.7 0.00077 19.4 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KND93240.1 - 3.8e-07 30.2 2.1 0.002 18.3 0.1 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain TraF PF13728.1 KND93240.1 - 0.0023 17.4 0.1 0.28 10.6 0.0 3.0 3 0 0 3 3 3 1 F plasmid transfer operon protein HyaE PF07449.6 KND93240.1 - 0.01 15.7 0.0 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KND93240.1 - 0.11 12.3 1.2 2.9 7.7 0.0 3.4 4 1 0 4 4 4 0 Thioredoxin domain Actin PF00022.14 KND93241.1 - 3.8e-15 55.1 0.0 3.9e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Actin DUF500 PF04366.7 KND93242.1 - 3.2e-25 87.9 0.0 7.5e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) Tyr-DNA_phospho PF06087.7 KND93243.1 - 4e-107 358.6 0.0 1.2e-106 356.9 0.0 1.6 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KND93243.1 - 0.02 14.6 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain MatE PF01554.13 KND93244.1 - 1.1e-48 164.9 24.1 7.3e-29 100.4 5.6 3.3 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.1 KND93244.1 - 0.00059 19.6 13.1 0.00059 19.6 9.1 3.8 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain NOGCT PF08155.6 KND93245.1 - 1.5e-29 101.4 2.0 3.4e-29 100.2 1.4 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KND93245.1 - 2.2e-26 91.5 0.6 6.5e-26 89.9 0.4 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KND93245.1 - 1.5e-15 57.2 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND93245.1 - 1e-08 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KND93245.1 - 0.00017 22.0 0.0 0.00062 20.2 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KND93245.1 - 0.022 14.5 0.9 7.5 6.3 0.0 2.9 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 KND93245.1 - 0.024 14.0 0.1 0.37 10.2 0.1 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF925 PF06042.6 KND93245.1 - 0.026 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) Pribosyltran PF00156.22 KND93246.1 - 0.0069 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.13 KND93247.1 - 1.8e-19 69.6 0.1 3e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KND93247.1 - 2.7e-07 30.5 7.8 1.3e-05 25.2 0.8 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND93247.1 - 3.5e-05 23.8 14.2 0.0015 18.7 4.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KND93247.1 - 0.0013 18.8 3.8 0.003 17.6 2.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KND93247.1 - 0.019 15.2 16.8 0.051 13.9 4.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KND93247.1 - 0.61 10.2 3.6 8 6.7 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KND93247.1 - 2.1 8.1 7.7 0.88 9.3 0.8 2.4 2 0 0 2 2 2 0 BED zinc finger GDI PF00996.13 KND93248.1 - 7.8e-176 584.6 0.0 1.3e-173 577.3 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KND93248.1 - 0.05 13.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 KND93249.1 - 2.8e-10 39.9 4.2 8.4e-10 38.4 2.9 1.8 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF3435 PF11917.3 KND93252.1 - 1.1e-57 195.6 0.0 1.4e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) NACHT PF05729.7 KND93256.1 - 1.1e-07 31.7 4.5 1.9e-05 24.3 0.1 3.0 4 0 0 4 4 4 2 NACHT domain AAA_22 PF13401.1 KND93256.1 - 2.1e-05 24.6 0.2 0.011 15.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 KND93256.1 - 0.015 14.3 0.6 0.11 11.4 0.0 2.4 3 0 0 3 3 3 0 KAP family P-loop domain AAA_16 PF13191.1 KND93256.1 - 0.026 14.5 4.9 0.052 13.5 0.1 3.1 1 1 1 2 2 2 0 AAA ATPase domain DUF2392 PF10288.4 KND93256.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Ank_5 PF13857.1 KND93256.1 - 0.12 12.7 0.0 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DNA_ligase_ZBD PF03119.11 KND93258.1 - 0.08 12.6 2.1 0.13 11.9 1.4 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Prok-RING_4 PF14447.1 KND93258.1 - 0.083 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ECM11 PF15463.1 KND93259.1 - 3.4e-39 134.3 2.7 3.4e-39 134.3 1.9 2.4 3 1 0 3 3 3 1 Extracellular mutant protein 11 Acyl-CoA_dh_1 PF00441.19 KND93261.1 - 1.2e-25 90.3 0.4 2.2e-25 89.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND93261.1 - 2.6e-22 79.5 0.9 3.8e-22 78.9 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KND93261.1 - 4.3e-15 54.9 0.0 9.9e-15 53.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KND93261.1 - 6.5e-09 36.1 0.1 1.3e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KND93261.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal RRM_1 PF00076.17 KND93262.1 - 3.5e-09 36.1 0.0 5.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND93262.1 - 1.2e-06 28.3 0.0 2.8e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND93262.1 - 0.00036 20.3 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.7 KND93264.1 - 4.5e-20 71.8 0.1 2.3e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Stress responsive A/B Barrel Domain MFS_1 PF07690.11 KND93266.1 - 2.7e-30 105.2 27.5 2.7e-30 105.2 19.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KND93266.1 - 0.0069 14.4 0.1 0.44 8.5 0.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PCP_red PF08369.5 KND93267.1 - 0.6 10.0 5.9 5.5 6.9 0.2 2.8 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit SKG6 PF08693.5 KND93268.1 - 0.02 14.1 0.1 0.11 11.8 0.1 2.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PCMT PF01135.14 KND93268.1 - 0.069 12.6 1.3 6.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DAP10 PF07213.6 KND93268.1 - 0.073 12.8 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 DAP10 membrane protein NAD_binding_6 PF08030.7 KND93269.1 - 3.3e-33 114.8 0.0 5.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KND93269.1 - 7.9e-20 70.7 0.0 2.6e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KND93269.1 - 9.9e-16 57.9 9.7 9.9e-16 57.9 6.7 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KND93269.1 - 0.0028 17.7 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KND93269.1 - 0.075 13.6 0.0 0.7 10.4 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain UQ_con PF00179.21 KND93271.1 - 6.9e-51 171.3 0.0 7.8e-51 171.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND93271.1 - 5.7e-05 22.8 0.0 6.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND93271.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KND93271.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain SGL PF08450.7 KND93275.1 - 0.00074 18.9 1.8 0.081 12.2 0.0 3.2 2 1 1 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 KND93275.1 - 0.032 13.8 2.5 0.26 11.0 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NHL PF01436.16 KND93275.1 - 0.034 14.0 0.1 3.7 7.6 0.0 3.6 3 0 0 3 3 3 0 NHL repeat RCC1_2 PF13540.1 KND93275.1 - 0.038 13.6 2.2 2.3 7.9 0.4 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat GSDH PF07995.6 KND93275.1 - 0.039 13.0 3.0 0.14 11.2 2.0 2.3 1 1 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Fungal_trans PF04082.13 KND93276.1 - 2.1e-23 82.5 0.0 3.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93276.1 - 5.4e-09 35.8 9.8 8.5e-09 35.1 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KND93277.1 - 4.8e-39 134.0 9.6 4.8e-39 134.0 6.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93277.1 - 3.2e-10 39.1 2.5 3.2e-10 39.1 1.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KND93277.1 - 0.00017 20.1 16.1 0.00076 17.9 2.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Mito_fiss_reg PF05308.6 KND93278.1 - 0.14 11.4 1.4 0.17 11.2 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2415 PF10313.4 KND93279.1 - 1.2e-10 40.9 0.0 2.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) DAO PF01266.19 KND93280.1 - 2.3e-50 171.4 7.4 2.7e-50 171.2 5.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND93280.1 - 0.00021 21.4 0.1 0.0016 18.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND93280.1 - 0.00079 19.3 0.2 0.002 18.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND93280.1 - 0.048 13.5 0.4 0.095 12.5 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND93280.1 - 0.064 12.3 1.8 0.34 9.9 1.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Mqo PF06039.10 KND93280.1 - 0.068 11.3 0.0 0.66 8.0 0.0 2.2 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Avl9 PF09794.4 KND93281.1 - 3.1e-145 483.4 0.0 3.9e-145 483.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 KND93281.1 - 3.3e-07 29.8 0.1 7.2e-06 25.4 0.1 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KND93281.1 - 4.1e-06 26.4 0.1 0.002 17.7 0.0 2.4 1 1 1 2 2 2 2 Stabilization of polarity axis Pyr_redox_2 PF07992.9 KND93282.1 - 4.6e-16 59.3 1.6 0.00044 20.1 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND93282.1 - 1.8e-08 34.6 2.8 2.4e-08 34.2 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND93282.1 - 2.9e-05 23.1 0.1 0.00023 20.1 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KND93282.1 - 0.00014 20.6 0.5 0.091 11.3 0.0 2.5 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KND93282.1 - 0.00026 21.0 0.6 0.16 11.9 0.3 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND93282.1 - 0.00045 19.2 2.3 0.13 11.1 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KND93282.1 - 0.00055 18.9 0.5 0.12 11.2 0.1 3.6 4 1 1 5 5 5 1 Lycopene cyclase protein TPP_enzyme_M PF00205.17 KND93282.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF4147 PF13660.1 KND93282.1 - 0.016 14.3 0.0 0.65 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) TrkA_N PF02254.13 KND93282.1 - 0.04 13.9 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 KND93282.1 - 0.097 11.4 2.6 1.8 7.3 2.1 2.3 2 1 0 2 2 2 0 FAD binding domain DUF1067 PF06362.6 KND93282.1 - 0.13 12.8 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) GIDA PF01134.17 KND93282.1 - 2 7.2 5.4 1.8 7.3 2.3 2.0 2 1 1 3 3 3 0 Glucose inhibited division protein A DAO PF01266.19 KND93284.1 - 1.8e-31 109.3 0.4 2.6e-31 108.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND93284.1 - 0.06 13.3 0.1 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AA_permease_2 PF13520.1 KND93285.1 - 1.5e-44 152.2 45.8 1.8e-44 151.9 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND93285.1 - 1.7e-23 82.7 37.4 2.4e-23 82.2 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KND93286.1 - 4e-36 124.5 0.0 5.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93286.1 - 1.8e-18 66.5 0.0 2.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND93286.1 - 0.0054 16.4 0.0 0.14 11.8 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND93286.1 - 0.085 11.8 0.0 0.41 9.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Aconitase PF00330.15 KND93287.1 - 7.8e-74 248.8 0.0 4.3e-47 160.6 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KND93287.1 - 8.7e-22 77.6 0.0 4.5e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF596 PF04591.7 KND93287.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Fungal_trans PF04082.13 KND93288.1 - 3.3e-21 75.3 0.7 5.5e-21 74.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 KND93289.1 - 8.6e-55 185.5 0.0 1.1e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PNPOx_C PF10590.4 KND93290.1 - 3.1e-20 71.3 4.6 3.1e-20 71.3 3.2 2.0 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KND93290.1 - 8.3e-17 60.9 0.0 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KND93290.1 - 0.039 14.2 0.0 0.077 13.3 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Cyclin_N PF00134.18 KND93291.1 - 9.2e-07 28.4 0.0 8.6e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain 2-oxoacid_dh PF00198.18 KND93292.1 - 5.2e-77 258.2 0.0 7.5e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KND93292.1 - 3.2e-16 58.7 3.2 6.5e-16 57.7 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KND93292.1 - 0.0096 15.1 9.5 0.011 14.8 4.0 2.4 1 1 2 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KND93292.1 - 0.071 12.7 0.4 0.46 10.1 0.1 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like DUF3614 PF12267.3 KND93292.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) CMV_1a PF12467.3 KND93292.1 - 7.4 6.9 10.2 20 5.5 5.9 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Complex1_LYR PF05347.10 KND93293.1 - 2.1e-06 27.4 1.7 4.9e-06 26.2 1.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND93293.1 - 2.7e-05 24.2 0.1 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Cys_Met_Meta_PP PF01053.15 KND93294.1 - 1.3e-38 132.3 0.0 1.7e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KND93294.1 - 0.0038 16.2 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II BSD PF03909.12 KND93294.1 - 0.16 11.7 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 BSD domain Gly-zipper_OmpA PF13436.1 KND93295.1 - 0.011 15.3 0.4 0.048 13.3 0.1 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DnaJ PF00226.26 KND93296.1 - 1.7e-24 85.3 1.1 1.7e-24 85.3 0.8 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_2 PF12756.2 KND93296.1 - 5.8e-10 39.1 2.7 5.6e-05 23.1 0.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KND93296.1 - 5.1e-09 36.0 1.0 5.1e-09 36.0 0.7 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND93296.1 - 6.2e-09 35.7 5.5 2e-08 34.1 1.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KND93296.1 - 1.7e-07 31.1 6.5 0.0026 18.0 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND93296.1 - 2.6e-06 27.3 5.5 0.018 15.3 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KND93296.1 - 2.8e-05 23.8 4.4 0.087 12.7 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND93296.1 - 0.029 14.6 1.2 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain DUF2256 PF10013.4 KND93296.1 - 0.082 12.6 1.0 7.6 6.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2387 PF09526.5 KND93296.1 - 0.76 9.7 3.5 1.3 9.0 0.8 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-met2 PF12907.2 KND93296.1 - 1 9.4 6.3 6.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding SPX PF03105.14 KND93297.1 - 5.6e-35 121.4 0.0 2.8e-34 119.1 0.0 2.1 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 KND93297.1 - 3.4e-08 32.9 9.7 3.4e-08 32.9 6.8 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND93297.1 - 4.1e-07 29.7 9.6 4.1e-07 29.7 6.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KND93297.1 - 6.3e-07 29.3 11.6 6.3e-07 29.3 8.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND93297.1 - 1.2e-06 28.0 9.3 1.2e-06 28.0 6.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND93297.1 - 3.8e-05 23.4 11.7 3.8e-05 23.4 8.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KND93297.1 - 0.0001 21.9 9.4 0.0001 21.9 6.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KND93297.1 - 0.003 17.2 7.1 0.0087 15.7 4.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KND93297.1 - 0.0059 16.6 3.8 0.017 15.2 2.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KND93297.1 - 0.81 9.5 6.2 2.4 7.9 3.8 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein ASFV_p27 PF06556.6 KND93297.1 - 0.92 9.4 3.0 0.63 9.9 0.3 1.9 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus DZR PF12773.2 KND93297.1 - 1.9 8.3 11.6 0.3 10.9 4.8 2.2 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 KND93297.1 - 4.7 6.8 15.8 0.42 10.2 6.8 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain G-patch PF01585.18 KND93298.1 - 4.3e-10 39.2 0.3 1.2e-09 37.8 0.2 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 KND93298.1 - 6.9e-10 38.4 0.0 1.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 KND93298.1 - 0.0037 17.0 0.5 0.013 15.2 0.3 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site BUD22 PF09073.5 KND93298.1 - 0.18 10.8 15.2 0.3 10.1 10.5 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_C54 PF03416.14 KND93299.1 - 8.8e-89 297.3 0.0 1.3e-88 296.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.19 KND93300.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KND93300.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND93301.1 - 2.2e-22 78.9 0.2 3.2e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KND93301.1 - 4.3e-05 23.4 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KND93301.1 - 0.00021 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KND93301.1 - 0.0092 14.6 2.1 0.011 14.3 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KND93301.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 KND93301.1 - 0.046 14.2 0.5 0.062 13.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) TP_methylase PF00590.15 KND93302.1 - 4.3e-20 72.3 0.0 7.6e-20 71.5 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 KND93303.1 - 1.3e-06 28.4 0.2 2.3e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 KND93303.1 - 1.8e-05 24.5 12.2 1.8e-05 24.5 8.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 KND93303.1 - 6.3e-05 23.0 0.3 0.00012 22.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KND93303.1 - 0.0082 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-U1 PF06220.7 KND93303.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.21 KND93303.1 - 0.2 12.0 0.4 0.38 11.1 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3340 PF11818.3 KND93303.1 - 0.62 10.0 18.3 0.2 11.5 7.7 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Caudo_TAP PF02413.12 KND93303.1 - 2.5 8.2 10.8 0.83 9.8 5.7 1.6 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF1764 PF08576.5 KND93303.1 - 6.8 7.5 9.0 14 6.5 4.2 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Caldesmon PF02029.10 KND93303.1 - 8.9 4.6 25.9 0.16 10.3 12.4 1.9 2 0 0 2 2 2 0 Caldesmon IPK PF03770.11 KND93303.1 - 9.1 5.8 8.1 38 3.8 5.6 2.0 1 1 0 1 1 1 0 Inositol polyphosphate kinase UQ_con PF00179.21 KND93304.1 - 1.7e-35 121.4 0.0 2e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND93304.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.1 KND93305.1 - 4.8e-24 85.0 0.0 1.3e-22 80.4 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KND93305.1 - 0.00024 21.3 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-TFIIIC PF12660.2 KND93306.1 - 9.1e-11 41.5 1.3 2.6e-10 40.0 0.7 1.9 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex DUF2688 PF10892.3 KND93306.1 - 0.2 11.3 2.9 0.37 10.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) DUF2688 PF10892.3 KND93307.1 - 0.2 11.3 2.9 0.36 10.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Peptidase_C13 PF01650.13 KND93308.1 - 3.1e-40 138.0 0.3 4.1e-40 137.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pyridox_oxidase PF01243.15 KND93310.1 - 6e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cation_efflux PF01545.16 KND93311.1 - 4.6e-58 196.5 1.0 6.6e-58 196.0 0.7 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KND93311.1 - 7.2e-06 25.2 45.5 0.0087 15.0 10.1 3.0 1 1 1 2 2 2 2 ZIP Zinc transporter Mito_carr PF00153.22 KND93312.1 - 1.3e-58 194.6 5.7 1.4e-19 69.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL PF00657.17 KND93313.1 - 1.4e-12 47.9 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KND93313.1 - 0.00011 22.4 0.3 0.0004 20.5 0.2 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF167 PF02594.11 KND93314.1 - 6.8e-15 54.7 0.0 9.4e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 DUF2410 PF10307.4 KND93316.1 - 6.4e-78 260.6 0.0 8.2e-78 260.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) GRP PF07172.6 KND93316.1 - 3.1 8.3 33.4 0.078 13.4 16.3 2.3 2 0 0 2 2 2 0 Glycine rich protein family Pkinase PF00069.20 KND93317.1 - 1.2e-25 90.1 0.0 2.2e-25 89.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93317.1 - 1.6e-06 27.3 0.0 0.04 12.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase tRNA_m1G_MT PF01746.16 KND93318.1 - 1.9e-30 105.8 0.0 2.5e-23 82.6 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DNA_primase_S PF01896.14 KND93319.1 - 6.7e-55 184.8 0.1 1.4e-54 183.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit COQ9 PF08511.6 KND93322.1 - 1.9e-28 97.7 0.0 2.8e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.14 KND93324.1 - 4e-23 81.7 1.3 1.6e-22 79.8 0.9 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND93324.1 - 5.6e-16 59.4 8.2 5.6e-16 59.4 5.7 4.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KND93324.1 - 2.5e-05 24.3 1.3 0.0014 18.6 0.5 2.8 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KND93324.1 - 0.0018 17.4 0.3 0.0018 17.4 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain SMC_hinge PF06470.8 KND93324.1 - 0.0025 17.7 0.2 0.018 14.9 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.1 KND93324.1 - 0.0047 16.8 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KND93324.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KND93324.1 - 0.5 10.6 24.4 0.25 11.6 1.2 5.2 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 KND93324.1 - 0.95 8.5 5.7 13 4.8 0.1 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KND93324.1 - 3.3 7.5 27.8 4.7 7.0 0.1 6.3 4 2 1 6 6 6 0 Protein of unknown function (DUF1664) MIF4G PF02854.14 KND93326.1 - 1.4e-20 73.6 0.1 1.9e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain SRP14 PF02290.10 KND93327.1 - 6e-23 80.5 0.0 8.2e-23 80.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein RRM_1 PF00076.17 KND93329.1 - 1.8e-45 152.4 0.0 3.8e-18 64.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND93329.1 - 2.5e-37 126.7 0.0 5.4e-15 55.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND93329.1 - 2.6e-20 72.0 0.0 1.4e-06 28.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KND93329.1 - 8.3e-05 22.2 0.1 5.7 6.7 0.0 4.0 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 KND93329.1 - 0.00019 21.2 0.0 1.1 9.1 0.0 3.9 4 0 0 4 4 4 1 RNA binding motif ATP-grasp_2 PF08442.5 KND93329.1 - 0.0011 18.3 0.0 0.066 12.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Pyr_redox_dim PF02852.17 KND93330.1 - 3e-39 133.4 1.7 1.1e-38 131.6 0.0 2.8 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KND93330.1 - 1e-35 123.4 13.3 7.3e-35 120.6 8.7 3.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND93330.1 - 1.2e-25 89.6 10.6 4.5e-21 75.0 0.9 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND93330.1 - 1.8e-11 43.8 2.4 2.4e-06 27.4 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND93330.1 - 1.8e-10 41.2 0.1 6.8e-07 29.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KND93330.1 - 5e-10 38.7 9.7 4.2e-08 32.4 2.8 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 KND93330.1 - 5.3e-10 38.9 8.4 1.3e-09 37.6 0.2 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.19 KND93330.1 - 1.6e-09 37.1 18.2 5.7e-05 22.1 1.1 4.1 2 2 2 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND93330.1 - 5.9e-09 35.2 7.1 5.1e-07 28.8 1.7 2.9 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 KND93330.1 - 2.9e-07 29.3 13.1 7.9e-05 21.2 1.4 4.0 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.12 KND93330.1 - 3.9e-07 29.4 2.7 8.6e-05 21.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 KND93330.1 - 4.1e-05 22.7 9.7 0.067 12.2 0.9 3.2 3 0 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 KND93330.1 - 5.4e-05 22.8 3.0 0.085 12.4 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KND93330.1 - 0.00019 20.4 2.4 0.0082 15.1 0.1 2.8 3 1 0 3 3 3 1 Lycopene cyclase protein K_oxygenase PF13434.1 KND93330.1 - 0.00019 20.4 0.6 0.34 9.7 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KND93330.1 - 0.024 13.7 0.3 0.058 12.4 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 KND93330.1 - 0.026 14.7 6.2 2 8.7 0.4 3.3 2 2 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KND93330.1 - 0.028 14.0 0.4 0.028 14.0 0.3 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KND93330.1 - 0.092 11.8 1.2 2.4 7.2 0.1 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KND93330.1 - 0.13 10.9 7.2 0.049 12.2 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 KND93330.1 - 1.5 8.1 6.2 2.9 7.2 0.3 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MA3 PF02847.12 KND93331.1 - 6.4e-10 38.7 0.0 3.5e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 MA3 domain MFS_1 PF07690.11 KND93333.1 - 1.4e-33 116.0 24.5 1.4e-26 93.1 4.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93333.1 - 3.6e-11 42.3 3.6 3.6e-11 42.3 2.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KND93333.1 - 6.2e-05 21.5 5.2 6.2e-05 21.5 3.6 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 KND93333.1 - 0.091 10.8 4.9 0.013 13.6 0.5 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector LCAT PF02450.10 KND93334.1 - 2.7e-95 319.6 0.0 3.7e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2013 PF09431.5 KND93334.1 - 4.9e-49 165.6 3.9 1.1e-48 164.5 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Lipase_2 PF01674.13 KND93334.1 - 0.037 13.3 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.5 KND93334.1 - 0.096 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF1917 PF08939.5 KND93336.1 - 7.7e-57 192.8 0.1 1.4e-56 192.0 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.19 KND93337.1 - 7.2e-17 61.1 0.0 1.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KND93337.1 - 4.7e-10 39.0 0.0 7.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KND93337.1 - 1.2e-09 38.3 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND93337.1 - 1.4e-09 37.9 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND93337.1 - 1.6e-06 28.0 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND93337.1 - 2.9e-06 27.4 0.0 3.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND93337.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND93337.1 - 0.028 14.3 0.1 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallopep PF12044.3 KND93338.1 - 5.9e-158 525.7 0.0 1e-157 524.9 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KND93338.1 - 2.3e-05 24.2 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_2 PF13574.1 KND93338.1 - 0.039 14.0 0.2 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KND93338.1 - 0.05 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Whi5 PF08528.6 KND93339.1 - 1.1e-11 44.0 0.1 1.9e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Whi5 like eIF_4EBP PF05456.6 KND93339.1 - 2.3 7.9 5.5 1.8 8.3 0.6 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PH PF00169.24 KND93340.1 - 9.2e-11 41.8 0.1 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KND93340.1 - 0.0087 13.6 0.9 0.013 13.1 0.6 1.2 1 0 0 1 1 1 1 Prominin Proteasome PF00227.21 KND93340.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit CDP-OH_P_transf PF01066.16 KND93341.1 - 6.2e-14 52.1 2.4 1.3e-13 51.0 1.6 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Transp_cyt_pur PF02133.10 KND93342.1 - 3e-94 316.0 33.5 3.5e-94 315.8 23.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Xpo1 PF08389.7 KND93343.1 - 1e-06 28.7 0.7 2.5e-05 24.2 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 KND93343.1 - 3.6e-05 23.6 0.1 0.00013 21.7 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain IFRD PF05004.8 KND93343.1 - 0.0011 18.0 0.1 0.0026 16.8 0.1 1.5 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) MOR2-PAG1_N PF14222.1 KND93343.1 - 0.065 11.9 0.1 0.27 9.8 0.0 1.8 2 0 0 2 2 2 0 Cell morphogenesis N-terminal IPPT PF01715.12 KND93343.1 - 0.2 10.6 0.0 0.42 9.5 0.0 1.4 1 0 0 1 1 1 0 IPP transferase DASH_Ask1 PF08655.5 KND93344.1 - 9.3e-33 111.8 0.0 1.7e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 YqfQ PF14181.1 KND93344.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.4 3 0 0 3 3 3 0 YqfQ-like protein Spc97_Spc98 PF04130.8 KND93345.1 - 1e-64 218.8 0.0 2.4e-51 174.6 0.0 2.1 1 1 1 2 2 2 2 Spc97 / Spc98 family CHD5 PF04420.9 KND93345.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 CHD5-like protein Eaf7 PF07904.8 KND93346.1 - 1.1e-27 95.7 0.1 3.2e-27 94.3 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 MAP65_ASE1 PF03999.7 KND93346.1 - 0.11 11.0 8.6 0.19 10.2 6.0 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Nop14 PF04147.7 KND93346.1 - 0.22 9.3 7.7 0.32 8.8 5.3 1.2 1 0 0 1 1 1 0 Nop14-like family ResIII PF04851.10 KND93347.1 - 1.1e-24 87.3 0.0 1.9e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KND93347.1 - 1.9e-15 56.4 0.0 6e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND93347.1 - 4e-14 52.4 0.1 7.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.4 KND93347.1 - 0.0013 17.3 0.0 0.0021 16.7 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 KND93347.1 - 0.002 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KND93347.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 KND93347.1 - 0.14 12.1 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 Helicase C-terminal domain KH_1 PF00013.24 KND93348.1 - 1e-25 89.1 1.4 1.5e-07 30.9 0.2 7.1 8 0 0 8 8 8 4 KH domain KH_3 PF13014.1 KND93348.1 - 6.8e-25 86.2 3.5 3.5e-05 23.3 0.0 6.0 6 0 0 6 6 6 5 KH domain PRRSV_Env PF02340.10 KND93348.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 PRRSV putative envelope protein DUF1635 PF07795.6 KND93348.1 - 0.32 10.3 2.4 0.66 9.3 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Rrn6 PF10214.4 KND93350.1 - 1.7 6.6 3.4 2.5 6.0 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HAD_2 PF13419.1 KND93351.1 - 1.2e-32 113.5 0.1 1.5e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND93351.1 - 2e-05 25.0 0.0 6.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND93351.1 - 4.8e-05 22.9 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 KND93351.1 - 0.06 12.9 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase Med21 PF11221.3 KND93352.1 - 4.4e-44 149.9 5.3 4.8e-44 149.8 3.7 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 KND93352.1 - 0.0022 17.6 0.5 0.0022 17.6 0.4 2.7 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 CtIP_N PF10482.4 KND93352.1 - 0.0041 16.9 2.9 0.013 15.2 1.0 2.1 1 1 1 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain TMCO5 PF14992.1 KND93352.1 - 0.0098 15.0 2.9 0.011 14.9 2.0 1.2 1 0 0 1 1 1 1 TMCO5 family GAS PF13851.1 KND93352.1 - 0.017 14.3 4.2 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KND93352.1 - 0.018 15.1 2.0 0.025 14.7 0.6 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 KND93352.1 - 0.021 13.5 2.6 0.023 13.3 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phi-29_GP16_7 PF06720.6 KND93352.1 - 0.031 13.9 1.7 0.074 12.7 0.5 2.0 1 1 1 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Spore_III_AB PF09548.5 KND93352.1 - 0.069 12.9 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Herpes_UL6 PF01763.11 KND93352.1 - 0.09 10.9 0.5 0.084 11.0 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1843 PF08898.5 KND93352.1 - 0.16 12.0 2.4 0.47 10.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) APG6 PF04111.7 KND93352.1 - 0.29 10.1 6.4 0.35 9.8 4.4 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Pup PF05639.6 KND93352.1 - 0.44 11.0 4.9 0.29 11.6 1.9 1.8 2 0 0 2 2 1 0 Pup-like protein Mnd1 PF03962.10 KND93352.1 - 0.46 10.1 4.6 1 8.9 3.2 1.9 1 1 0 1 1 1 0 Mnd1 family CENP-Q PF13094.1 KND93352.1 - 0.47 10.4 8.2 0.36 10.8 4.7 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 KND93352.1 - 0.66 9.8 9.2 6.5 6.5 5.8 2.6 1 1 1 2 2 2 0 Tropomyosin like Seryl_tRNA_N PF02403.17 KND93352.1 - 2.7 8.0 8.6 7.5 6.6 2.4 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KND93352.1 - 4.4 6.8 6.5 4.7 6.7 3.0 2.2 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 KND93352.1 - 4.5 7.1 11.3 1 9.2 5.5 1.7 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding PP28 PF10252.4 KND93353.1 - 3.6e-26 90.9 15.0 3.6e-26 90.9 10.4 3.1 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CAF-1_p150 PF11600.3 KND93353.1 - 0.9 8.8 42.0 0.033 13.5 18.5 2.1 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SURF6 PF04935.7 KND93354.1 - 3.1e-47 160.6 37.3 3.1e-47 160.6 25.8 3.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KND93354.1 - 7.2e-19 67.6 0.4 7.2e-19 67.6 0.3 7.4 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.6 KND93355.1 - 6.3e-64 215.8 0.1 8.2e-64 215.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GTP_EFTU PF00009.22 KND93358.1 - 3.3e-39 134.2 3.7 1.9e-38 131.8 2.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KND93358.1 - 7.9e-26 90.0 0.3 1.8e-25 88.9 0.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KND93358.1 - 4e-07 29.9 0.1 9.4e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KND93358.1 - 4e-07 30.0 0.0 0.00045 20.2 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Miro PF08477.8 KND93358.1 - 2.5e-05 24.7 0.1 2.5e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 KND93358.1 - 4.2e-05 23.0 0.2 9.9e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 KND93358.1 - 7.1e-05 22.3 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.16 KND93358.1 - 0.00018 20.8 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND93358.1 - 0.00055 19.2 0.2 0.0014 17.8 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KND93358.1 - 0.0016 17.7 0.2 0.0036 16.5 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KND93358.1 - 0.046 13.2 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF367 PF04034.8 KND93359.1 - 2.6e-46 156.3 0.1 3.6e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KND93359.1 - 6.5e-12 44.8 0.7 1.3e-11 43.8 0.5 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI HUN PF08729.5 KND93360.1 - 9.4e-13 47.8 0.2 2e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Serglycin PF04360.7 KND93360.1 - 5 6.8 9.2 9.1 6.0 0.6 3.0 3 0 0 3 3 3 0 Serglycin Macoilin PF09726.4 KND93360.1 - 7.9 4.6 8.5 15 3.7 5.9 1.3 1 0 0 1 1 1 0 Transmembrane protein VHS PF00790.14 KND93363.1 - 4.3e-45 152.8 0.0 1.4e-44 151.1 0.0 1.9 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 KND93363.1 - 1.5e-24 85.8 0.2 3.7e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KND93363.1 - 3.8e-20 72.3 0.1 8.5e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain M11L PF11099.3 KND93363.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11L like Pro-kuma_activ PF09286.6 KND93365.1 - 6.4e-39 133.2 0.0 1.3e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KND93365.1 - 1.8e-06 27.3 0.2 2.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Metallophos PF00149.23 KND93368.1 - 2.4e-08 33.6 1.1 1.6e-07 30.9 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CAP_N PF01213.14 KND93368.1 - 0.13 11.5 0.9 0.18 11.0 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fungal_trans_2 PF11951.3 KND93369.1 - 1.1e-08 34.1 0.6 1.6e-08 33.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93369.1 - 0.00015 21.6 3.9 0.00025 20.8 2.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHO_dh PF01180.16 KND93371.1 - 3.5e-65 219.8 0.1 7.9e-54 182.6 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 KND93371.1 - 3.9e-06 26.2 1.3 0.027 13.7 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 KND93371.1 - 0.15 10.8 5.4 0.84 8.4 1.9 2.5 2 1 0 2 2 2 0 FMN-dependent dehydrogenase TOM13 PF08219.6 KND93372.1 - 4.3e-32 109.6 0.0 5.5e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 KND93373.1 - 2.8e-26 92.4 7.2 2.8e-26 92.4 5.0 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein DUF2951 PF11166.3 KND93373.1 - 2.1 8.2 5.8 7.8 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) PEP_mutase PF13714.1 KND93374.1 - 7.8e-57 192.2 0.2 8.8e-57 192.0 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2848 PF11010.3 KND93374.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) tRNA_int_endo PF01974.12 KND93375.1 - 3.5e-19 68.3 0.0 6.8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KND93375.1 - 3e-06 26.7 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Glyco_transf_21 PF13506.1 KND93376.1 - 4.8e-12 45.5 0.1 7.8e-06 25.2 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KND93376.1 - 1.6e-11 44.4 0.0 3.3e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KND93376.1 - 0.00018 21.2 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 SGS PF05002.10 KND93377.1 - 3.8e-27 93.8 0.8 3.8e-27 93.8 0.6 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.11 KND93377.1 - 5.9e-08 33.1 0.0 1.1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KND93377.1 - 3.7e-07 29.6 3.5 0.00011 21.8 0.0 2.8 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KND93377.1 - 0.0025 17.6 2.5 0.16 11.9 0.2 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KND93377.1 - 0.0042 17.7 1.7 1.2 9.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND93377.1 - 0.025 14.1 0.1 0.1 12.2 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat OPT PF03169.10 KND93378.1 - 1.1e-145 486.5 47.3 1.2e-145 486.3 32.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 KND93379.1 - 1.7e-31 109.2 31.0 5.3e-27 94.4 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93379.1 - 7.6e-30 103.8 26.7 5.7e-28 97.6 18.5 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter PIRT PF15099.1 KND93379.1 - 0.086 12.0 4.0 0.056 12.6 0.4 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family ABC2_membrane PF01061.19 KND93380.1 - 5.9e-94 313.1 56.5 1.7e-50 171.0 15.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KND93380.1 - 7.2e-39 131.6 10.7 2.8e-35 120.0 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KND93380.1 - 8.6e-30 103.8 0.0 8.3e-16 58.5 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KND93380.1 - 9.9e-21 73.6 0.0 2.6e-20 72.2 0.0 1.8 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KND93380.1 - 7.8e-07 29.0 1.6 0.011 15.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KND93380.1 - 8.5e-07 28.5 0.3 0.00088 18.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KND93380.1 - 3.1e-05 23.1 15.7 3.1e-05 23.1 10.9 3.4 3 1 0 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 KND93380.1 - 0.0001 21.5 0.1 0.0037 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND93380.1 - 0.00019 21.4 0.6 0.0095 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KND93380.1 - 0.00027 20.3 1.1 0.025 14.1 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KND93380.1 - 0.00099 19.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KND93380.1 - 0.0014 18.7 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KND93380.1 - 0.0015 18.0 2.0 0.011 15.1 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KND93380.1 - 0.0035 16.6 0.1 0.12 11.5 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 KND93380.1 - 0.0051 16.9 0.6 0.9 9.7 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND93380.1 - 0.0063 17.3 0.0 0.39 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND93380.1 - 0.0085 15.8 1.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KND93380.1 - 0.012 15.9 0.1 0.32 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KND93380.1 - 0.049 14.1 0.1 19 5.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KND93380.1 - 0.097 12.3 1.5 4.1 7.0 0.3 2.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KND93380.1 - 0.1 12.5 0.2 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KND93380.1 - 0.25 10.8 0.7 9.2 5.7 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KND93380.1 - 0.41 10.2 2.0 5.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KND93380.1 - 0.52 8.9 0.0 2.6 6.6 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein adh_short PF00106.20 KND93381.1 - 4.1e-06 26.8 0.1 6.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND93381.1 - 0.0015 18.2 0.1 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.17 KND93382.1 - 2.7e-53 181.1 0.0 3.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VCBS PF13517.1 KND93383.1 - 4.7e-32 110.1 41.2 5.4e-09 36.2 3.6 7.3 4 2 1 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 KND93383.1 - 6.4e-24 85.0 0.0 8.2e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.18 KND93383.1 - 7e-20 70.1 34.6 0.0035 16.9 0.6 8.6 8 0 0 8 8 8 7 FG-GAP repeat Lipase_GDSL PF00657.17 KND93383.1 - 3.4e-13 49.9 0.5 5e-12 46.1 0.0 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 KND93383.1 - 8.6e-13 48.1 12.6 0.16 11.4 0.0 7.9 4 3 3 8 8 8 6 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 KND93383.1 - 0.2 11.3 0.1 0.5 10.0 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SPC22 PF04573.7 KND93384.1 - 9e-32 109.7 0.1 4.7e-23 81.3 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.14 KND93385.1 - 8.6e-34 117.0 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 KND93386.1 - 9.4e-29 98.2 5.1 2.4e-07 30.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nha1_C PF08619.5 KND93386.1 - 0.0048 16.2 9.4 0.011 14.9 6.5 1.5 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus PQQ_3 PF13570.1 KND93386.1 - 0.065 13.5 0.1 3 8.2 0.0 3.1 2 0 0 2 2 2 0 PQQ-like domain Proteasome PF00227.21 KND93387.1 - 5.8e-38 130.0 0.0 9.6e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit zf-RanBP PF00641.13 KND93388.1 - 1.1e-18 65.9 12.5 4.3e-11 41.6 0.8 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KND93388.1 - 6.6e-09 35.2 0.0 2e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KND93388.1 - 7e-07 29.6 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KND93388.1 - 9.3e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KND93388.1 - 4.9 7.0 11.1 1 9.2 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 KND93390.1 - 7e-39 130.3 0.8 4.5e-09 35.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KND93390.1 - 3.5e-26 90.9 0.1 8.2e-26 89.7 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 KND93391.1 - 4.8e-84 281.4 0.0 7.2e-84 280.8 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DEAD PF00270.24 KND93392.1 - 2.1e-45 154.2 0.0 4.6e-44 149.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND93392.1 - 2.9e-27 94.3 0.1 5.8e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND93392.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KND93392.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sugar_tr PF00083.19 KND93393.1 - 1e-108 363.8 22.1 1.3e-108 363.5 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND93393.1 - 1e-29 103.3 21.2 1e-29 103.3 14.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2929 PF11151.3 KND93393.1 - 4.1 7.5 9.2 0.39 10.8 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) ADH_N PF08240.7 KND93394.1 - 6.2e-08 32.3 0.2 2.8e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CarboxypepD_reg PF13620.1 KND93394.1 - 0.053 13.5 1.1 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain GCD14 PF08704.5 KND93395.1 - 4.5e-64 216.2 0.0 5.2e-47 160.4 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 KND93395.1 - 0.0037 17.8 0.0 0.012 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND93395.1 - 0.0057 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA-synt_1e PF01406.14 KND93396.1 - 1.2e-112 375.9 0.0 1.9e-112 375.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KND93396.1 - 5.9e-06 25.1 0.2 0.091 11.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) UQ_con PF00179.21 KND93397.1 - 2e-51 173.0 0.0 2.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_18 PF00704.23 KND93398.1 - 5.1e-10 39.3 0.0 1.3e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF1212 PF06738.7 KND93399.1 - 1.7e-37 128.7 14.7 5.7e-33 114.0 0.2 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KND93399.1 - 2.9e-27 95.1 12.4 2.9e-27 95.1 8.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DUF4398 PF14346.1 KND93400.1 - 0.012 15.6 3.0 0.04 13.9 2.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) LSM PF01423.17 KND93401.1 - 1.4e-15 56.6 0.2 1.9e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain TPR_11 PF13414.1 KND93402.1 - 1.4e-10 40.6 0.5 7.1e-09 35.1 0.0 3.3 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 KND93402.1 - 4.9e-06 26.0 0.9 1.8 8.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND93402.1 - 7.4e-05 22.1 0.8 0.68 9.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND93402.1 - 0.0004 20.2 3.2 0.0033 17.3 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat UBA PF00627.26 KND93402.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain DIOX_N PF14226.1 KND93403.1 - 5.8e-30 104.2 0.0 1.3e-29 103.0 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND93403.1 - 9.1e-20 70.8 0.0 1.6e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KND93404.1 - 2e-09 37.2 4.2 2e-09 37.2 2.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KND93405.1 - 4.9e-10 38.9 0.7 4e-07 29.4 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KND93405.1 - 6.6e-09 35.1 1.2 2.3e-07 30.0 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND93405.1 - 1.5e-08 34.5 0.4 2.1e-07 30.8 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND93405.1 - 2.2e-05 23.4 1.5 3.8e-05 22.7 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND93405.1 - 0.00034 19.1 0.5 0.00054 18.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KND93405.1 - 0.00093 19.1 1.3 0.0061 16.4 0.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KND93405.1 - 0.0012 18.0 0.1 0.057 12.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KND93405.1 - 0.0016 17.4 0.5 0.6 8.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KND93405.1 - 0.024 13.7 0.2 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KND93405.1 - 0.025 14.3 1.8 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KND93405.1 - 0.026 13.3 1.1 0.039 12.8 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KND93405.1 - 0.041 12.9 1.6 0.062 12.3 1.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 KND93405.1 - 0.067 12.6 0.3 0.14 11.6 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 KND93405.1 - 0.074 11.6 0.9 0.19 10.3 0.1 1.9 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KND93405.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KND93405.1 - 0.11 12.0 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KND93405.1 - 0.16 12.4 1.0 0.38 11.1 0.7 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KND93406.1 - 8.9e-21 73.9 40.2 8.6e-18 64.1 12.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nop16 PF09420.5 KND93408.1 - 1.3e-47 161.9 0.2 1.5e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 HlyC PF02794.11 KND93408.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family Init_tRNA_PT PF04179.7 KND93409.1 - 5.8e-36 124.3 0.0 3.9e-29 101.8 0.0 2.0 2 0 0 2 2 2 2 Initiator tRNA phosphoribosyl transferase GFO_IDH_MocA PF01408.17 KND93410.1 - 1.9e-10 41.2 0.0 4.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 KND93410.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Saccharop_dh PF03435.13 KND93410.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase LSM PF01423.17 KND93411.1 - 2.1e-21 75.2 0.1 2.3e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 KND93412.1 - 4.4e-11 42.5 0.0 6.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Peptidase_M41 PF01434.13 KND93413.1 - 1.5e-75 253.3 0.9 2.1e-75 252.8 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 KND93413.1 - 3.4e-41 140.5 0.0 7.2e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KND93413.1 - 1e-08 35.2 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KND93413.1 - 0.0019 17.9 0.0 0.0074 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KND93413.1 - 0.0021 16.8 0.1 0.0055 15.4 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KND93413.1 - 0.0033 18.2 0.5 0.03 15.1 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_2 PF07724.9 KND93413.1 - 0.0077 16.1 0.0 0.062 13.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KND93413.1 - 0.0086 16.2 0.1 0.71 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND93413.1 - 0.0089 15.4 0.7 0.033 13.5 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KND93413.1 - 0.009 15.7 1.8 0.053 13.2 0.8 2.3 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KND93413.1 - 0.018 14.1 0.1 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 KND93413.1 - 0.032 14.2 1.4 0.59 10.1 0.1 3.1 3 1 0 4 4 4 0 AAA ATPase domain RuvB_N PF05496.7 KND93413.1 - 0.037 13.0 0.0 0.08 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KND93413.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KND93413.1 - 0.055 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Pex14_N PF04695.8 KND93413.1 - 0.5 10.4 4.9 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA_pol_L_2 PF13656.1 KND93414.1 - 2.5e-22 78.0 0.0 3.6e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KND93414.1 - 2.1e-06 26.7 0.0 3.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ecl1 PF12855.2 KND93414.1 - 0.029 13.6 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Life-span regulatory factor HCO3_cotransp PF00955.16 KND93415.1 - 3.6e-34 118.2 3.2 1.9e-25 89.5 0.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family HCO3_cotransp PF00955.16 KND93416.1 - 3.8e-07 29.1 0.2 4.9e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 HCO3- transporter family 3HCDH_N PF02737.13 KND93417.1 - 5.4e-52 176.0 1.4 7.1e-52 175.6 1.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KND93417.1 - 1.6e-33 114.9 0.0 3.2e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KND93417.1 - 0.00062 19.6 0.3 0.0011 18.7 0.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 KND93417.1 - 0.0074 15.3 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 KND93417.1 - 0.012 15.6 0.9 0.047 13.7 0.6 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND93417.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.21 KND93417.1 - 0.022 14.3 0.2 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_Gly3P_dh_N PF01210.18 KND93417.1 - 0.027 14.1 1.0 0.063 13.0 0.7 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 KND93417.1 - 0.059 13.7 0.2 0.39 11.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KND93417.1 - 0.068 13.6 2.4 0.14 12.5 0.9 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KND93417.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KND93417.1 - 0.093 12.7 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 KND93417.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_32 PF13679.1 KND93417.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain Lycopene_cycl PF05834.7 KND93417.1 - 0.19 10.6 0.7 0.3 9.9 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TIMELESS PF04821.9 KND93418.1 - 2.7e-95 318.6 1.4 5.2e-94 314.4 0.0 2.4 2 0 0 2 2 2 2 Timeless protein TIMELESS_C PF05029.8 KND93418.1 - 9.8e-30 104.0 3.7 9.8e-30 104.0 2.5 3.9 3 1 1 4 4 4 1 Timeless protein C terminal region Homeobox PF00046.24 KND93419.1 - 9.5e-18 63.5 2.8 1.9e-17 62.6 2.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KND93419.1 - 0.00038 20.0 1.0 0.0076 15.9 0.1 3.1 3 0 0 3 3 3 1 Homeobox KN domain Mac PF12464.3 KND93419.1 - 0.15 12.1 0.5 0.55 10.2 0.4 1.9 1 1 0 1 1 1 0 Maltose acetyltransferase TRAPPC9-Trs120 PF08626.6 KND93421.1 - 6.1e-127 424.6 0.0 4.4e-126 421.8 0.0 1.9 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF2051 PF09738.4 KND93421.1 - 0.41 9.8 0.1 0.73 9.0 0.1 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Pneumo_att_G PF05539.6 KND93421.1 - 1.5 8.1 3.3 2.7 7.3 2.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Sugar_tr PF00083.19 KND93422.1 - 5.2e-116 387.8 29.1 6.1e-116 387.6 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND93422.1 - 2.6e-20 72.4 29.3 2.6e-20 72.4 20.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Trehalase PF01204.13 KND93422.1 - 0.31 9.6 0.9 3.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Trehalase UPF0060 PF02694.10 KND93422.1 - 8.3 6.4 17.7 0.54 10.3 2.3 3.8 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family BRCT PF00533.21 KND93423.1 - 1.9e-08 34.3 0.0 4.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_L28e PF01778.12 KND93426.1 - 7.8e-34 116.5 2.4 7.8e-34 116.5 1.6 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KND93426.1 - 1.2e-22 79.9 23.3 1.2e-22 79.9 16.1 3.3 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.7 KND93426.1 - 0.0076 14.6 22.4 0.011 14.2 15.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Reovirus_cap PF00979.12 KND93426.1 - 0.08 11.8 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Nop14 PF04147.7 KND93426.1 - 0.85 7.4 29.5 1.1 7.0 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.17 KND93427.1 - 7.9e-45 152.1 0.0 9.8e-45 151.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND93427.1 - 8.2e-15 55.3 0.2 1.3e-14 54.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND93427.1 - 7.6e-07 28.5 0.0 9.5e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND93427.1 - 2.8e-06 26.8 0.0 1.1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND93427.1 - 1.6e-05 24.8 0.1 3.1e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KND93427.1 - 0.00024 20.3 0.0 0.00057 19.1 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KND93427.1 - 0.02 14.8 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KND93427.1 - 0.11 11.8 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.20 KND93428.1 - 1.5e-33 115.7 0.0 2.4e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KND93428.1 - 3.1e-18 65.7 7.9 6.5e-18 64.7 5.5 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain NPIP PF06409.6 KND93428.1 - 0.11 11.1 3.6 0.17 10.5 2.5 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Peptidase_C78 PF07910.8 KND93429.1 - 1.5e-30 105.9 0.0 3.3e-30 104.8 0.0 1.5 1 1 1 2 2 2 1 Peptidase family C78 Peptidase_C78 PF07910.8 KND93430.1 - 3.5e-08 32.8 0.0 3.6e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.11 KND93431.1 - 1.3e-51 174.6 0.0 1.4e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 KND93432.1 - 1.3e-12 48.1 0.9 7.7e-12 45.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND93432.1 - 1.4e-12 48.5 0.1 6.9e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KND93432.1 - 2.2e-05 24.6 0.0 0.00072 19.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KND93432.1 - 2.7e-05 24.1 0.5 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND93432.1 - 0.00052 19.9 0.1 0.00087 19.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KND93432.1 - 0.00061 19.5 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 KND93432.1 - 0.00074 19.5 0.1 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND93432.1 - 0.00083 19.5 0.0 0.0086 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 KND93432.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 KND93432.1 - 0.0032 16.7 0.1 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MobB PF03205.9 KND93432.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KND93432.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 KND93432.1 - 0.014 14.9 1.1 0.02 14.4 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 KND93432.1 - 0.015 14.8 0.1 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KND93432.1 - 0.017 14.6 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 KND93432.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KND93432.1 - 0.029 14.2 0.1 0.079 12.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase-like family IstB_IS21 PF01695.12 KND93432.1 - 0.034 13.5 0.1 0.064 12.6 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 KND93432.1 - 0.035 13.8 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KND93432.1 - 0.038 13.4 0.5 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 KND93432.1 - 0.047 13.1 0.1 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 KND93432.1 - 0.047 12.2 0.1 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 KND93432.1 - 0.054 13.0 0.1 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KND93432.1 - 0.07 11.8 0.0 0.19 10.4 0.0 1.7 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 KND93432.1 - 0.12 11.7 1.4 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_14 PF13173.1 KND93432.1 - 0.14 12.1 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain DHC PF09626.5 KND93432.1 - 0.8 10.3 3.2 0.24 12.0 0.2 1.6 2 0 0 2 2 1 0 Dihaem cytochrome c Myosin_head PF00063.16 KND93433.1 - 1.1e-201 671.4 0.5 2.3e-201 670.4 0.3 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 KND93433.1 - 3.5e-34 116.8 3.4 1.3e-33 115.0 2.3 2.1 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KND93433.1 - 1.5e-11 42.8 40.3 0.00011 21.5 1.8 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 KND93433.1 - 0.00049 19.3 1.9 0.00097 18.4 1.3 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 KND93433.1 - 0.0015 18.6 0.0 0.0068 16.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND93433.1 - 0.027 14.2 0.0 0.089 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Tropomyosin_1 PF12718.2 KND93433.1 - 1.1 9.1 29.1 2 8.2 17.8 2.6 1 1 1 2 2 2 0 Tropomyosin like GAS PF13851.1 KND93433.1 - 3.5 6.7 27.9 1.9 7.6 7.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KND93433.1 - 3.7 7.9 18.5 3.3 8.0 2.5 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) 2-Hacid_dh_C PF02826.14 KND93434.1 - 1.2e-51 174.4 0.0 1.9e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND93434.1 - 1.4e-36 124.8 0.1 1.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KND93434.1 - 2.3e-05 24.2 0.2 6.4e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KND93434.1 - 0.0015 17.9 0.0 0.0049 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 KND93434.1 - 0.0061 16.4 0.4 0.013 15.3 0.1 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 KND93434.1 - 0.018 14.5 0.0 0.048 13.1 0.0 1.8 1 0 0 1 1 1 0 ACT domain Oxidored_nitro PF00148.14 KND93434.1 - 0.096 11.3 0.0 0.2 10.2 0.0 1.5 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Serglycin PF04360.7 KND93435.1 - 0.027 14.1 3.7 0.057 13.1 2.6 1.6 1 0 0 1 1 1 0 Serglycin Med3 PF11593.3 KND93435.1 - 9.8 5.2 7.5 15 4.7 5.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WAPL PF07814.8 KND93436.1 - 1.1e-10 40.7 0.0 3.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin RRM_1 PF00076.17 KND93437.1 - 4.6e-33 112.6 0.0 9.3e-16 57.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND93437.1 - 1.1e-17 63.7 0.0 1.8e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND93437.1 - 4.5e-16 58.4 0.0 6.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND93437.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KND93437.1 - 0.022 14.2 1.2 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Mito_carr PF00153.22 KND93438.1 - 8.6e-58 192.0 4.1 5.7e-20 70.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 KND93438.1 - 1.4e-17 62.8 0.1 3.2e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 TOM7 family zf-H2C2_2 PF13465.1 KND93439.1 - 6.8e-18 64.0 18.8 1.2e-08 34.8 0.3 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KND93439.1 - 1.4e-17 62.8 20.9 0.00027 21.0 0.8 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND93439.1 - 4.4e-14 51.7 18.1 0.0019 18.4 0.4 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KND93439.1 - 0.006 16.7 12.2 0.54 10.5 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type GAGA PF09237.6 KND93439.1 - 0.23 11.0 1.6 0.35 10.4 0.1 2.1 2 0 0 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.1 KND93439.1 - 1.2 9.1 7.1 8.7 6.4 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.6 KND93439.1 - 8.3 6.2 6.2 87 2.9 0.2 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Fer2 PF00111.22 KND93440.1 - 0.0075 15.9 0.7 0.013 15.2 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain WD40 PF00400.27 KND93441.1 - 5.5e-58 190.9 15.6 4e-08 32.8 0.0 11.5 11 1 0 11 11 11 9 WD domain, G-beta repeat Sec6 PF06046.8 KND93441.1 - 0.34 8.9 0.0 0.5 8.3 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Epimerase PF01370.16 KND93442.1 - 1e-18 67.6 0.1 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND93442.1 - 3.6e-18 66.2 2.7 5e-18 65.7 1.8 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KND93442.1 - 1.3e-10 40.6 0.6 1.7e-10 40.2 0.4 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KND93442.1 - 1e-07 30.9 0.0 2.3e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KND93442.1 - 2.5e-06 26.9 0.1 3.9e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KND93442.1 - 0.0005 19.0 0.1 0.0098 14.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 KND93442.1 - 0.041 13.8 0.1 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Saccharop_dh PF03435.13 KND93442.1 - 0.042 12.8 0.1 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 KND93442.1 - 0.058 13.3 0.4 0.22 11.4 0.3 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gifsy-2 PF13856.1 KND93442.1 - 0.11 12.5 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage RF-1 PF00472.15 KND93444.1 - 9.4e-27 93.0 0.7 1.6e-26 92.3 0.5 1.3 1 0 0 1 1 1 1 RF-1 domain DUF4570 PF15134.1 KND93444.1 - 0.76 9.6 4.1 1.2 8.9 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) GcrA PF07750.6 KND93444.1 - 1.7 8.8 8.2 0.26 11.4 2.1 2.0 1 1 1 2 2 2 0 GcrA cell cycle regulator DUF4544 PF15077.1 KND93444.1 - 3.4 7.0 6.2 4.8 6.6 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Actin PF00022.14 KND93445.1 - 2.9e-159 529.7 0.0 3.3e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KND93445.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ribosomal_L5_C PF00673.16 KND93446.1 - 5.4e-23 80.5 0.0 8.7e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KND93446.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Prenyltrans PF00432.16 KND93447.1 - 9.1e-28 95.5 8.1 9.6e-10 37.8 0.1 5.6 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KND93447.1 - 7.9e-25 87.4 1.1 4.4e-16 59.3 0.4 5.0 4 1 2 6 6 6 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KND93447.1 - 3.1e-24 85.1 0.3 4.1e-11 42.8 0.2 6.2 4 2 2 6 6 6 3 Prenyltransferase-like Pec_lyase PF09492.5 KND93447.1 - 0.0006 19.0 0.3 0.56 9.3 0.0 4.0 3 1 1 4 4 4 1 Pectic acid lyase A2M_comp PF07678.9 KND93447.1 - 0.0064 15.7 0.2 0.2 10.8 0.1 2.8 2 1 1 3 3 3 1 A-macroglobulin complement component TP6A_N PF04406.9 KND93448.1 - 1.5e-19 69.3 0.1 3.1e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SBF PF01758.11 KND93449.1 - 3.3e-52 176.6 10.9 7.3e-52 175.4 7.6 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family PLU-1 PF08429.6 KND93450.1 - 4e-97 325.1 11.9 3.5e-94 315.4 8.3 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KND93450.1 - 1.8e-42 144.1 0.3 3.8e-42 143.1 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KND93450.1 - 1.5e-25 88.8 0.0 3.9e-25 87.5 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KND93450.1 - 3e-16 58.8 28.7 8.1e-10 38.2 2.4 3.5 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 KND93450.1 - 2.6e-13 49.2 0.4 5.9e-13 48.1 0.3 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KND93450.1 - 1.2e-12 47.6 4.6 3.5e-12 46.2 3.2 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger Prok-JAB PF14464.1 KND93450.1 - 0.00083 18.8 0.0 0.0025 17.3 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-PHD-like PF15446.1 KND93450.1 - 0.0024 17.2 5.3 0.059 12.6 0.1 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KND93450.1 - 0.0099 15.1 0.8 0.0099 15.1 0.6 3.0 2 0 0 2 2 2 1 PHD-finger PAF-AH_p_II PF03403.8 KND93451.1 - 1.8e-35 121.9 0.0 1.9e-32 112.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KND93451.1 - 8.5e-11 41.7 0.0 2.4e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND93451.1 - 0.00012 22.0 1.7 0.00027 20.9 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KND93451.1 - 0.0052 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KND93451.1 - 0.03 13.1 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.13 KND93451.1 - 0.075 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Methyltransf_31 PF13847.1 KND93452.1 - 9.7e-13 47.9 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND93452.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND93452.1 - 1.9e-11 44.2 0.0 4.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND93452.1 - 1.7e-07 31.7 0.0 7.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND93452.1 - 3.8e-07 30.4 0.0 1.8e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND93452.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND93452.1 - 3.8e-06 27.1 0.0 8.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND93452.1 - 0.00057 19.0 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KND93452.1 - 0.0025 17.2 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_19 PF04672.7 KND93452.1 - 0.045 13.0 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_24 PF13578.1 KND93452.1 - 0.19 12.5 1.1 0.35 11.7 0.3 1.8 1 1 1 2 2 2 0 Methyltransferase domain AAA PF00004.24 KND93453.1 - 3.8e-18 65.9 0.0 6.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND93453.1 - 0.003 16.6 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KND93453.1 - 0.017 15.4 0.1 2 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KND93453.1 - 0.057 13.1 0.1 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 KND93453.1 - 0.059 13.3 0.5 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Zot PF05707.7 KND93453.1 - 0.087 12.2 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) KaiC PF06745.8 KND93453.1 - 0.27 10.3 1.3 1.1 8.3 0.7 1.9 1 1 1 2 2 2 0 KaiC Ank_2 PF12796.2 KND93454.1 - 2e-26 92.1 0.0 3.4e-15 56.1 0.0 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND93454.1 - 4.9e-15 55.2 0.9 2.7e-08 33.8 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND93454.1 - 1.5e-14 53.9 0.9 8.1e-07 29.3 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KND93454.1 - 1.7e-13 49.6 0.6 3.8e-08 32.7 0.5 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KND93454.1 - 5.4e-13 47.8 0.0 5.7e-06 26.0 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat DUF1110 PF06533.7 KND93454.1 - 0.0011 18.8 0.4 0.28 10.9 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1110) GATase_4 PF13230.1 KND93455.1 - 9e-18 63.9 0.0 1.7e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KND93455.1 - 2.6e-10 40.3 0.0 4.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KND93455.1 - 1e-06 27.7 0.0 9.9e-05 21.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II SoxD PF04267.7 KND93455.1 - 0.24 11.2 0.9 9.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family WD40 PF00400.27 KND93456.1 - 4.1e-19 67.6 6.5 0.0027 17.5 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat GET2 PF08690.5 KND93456.1 - 0.1 11.8 1.0 0.17 11.0 0.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Heme_oxygenase PF01126.15 KND93457.1 - 3.6e-09 36.4 0.0 1.4e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Heme oxygenase GSHPx PF00255.14 KND93459.1 - 2.8e-41 139.2 0.0 3.7e-41 138.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KND93459.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND93459.1 - 0.0056 16.2 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF4174 PF13778.1 KND93459.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) F-box PF00646.28 KND93461.1 - 0.00027 20.4 0.6 0.00081 18.9 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KND93461.1 - 0.0036 16.9 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like polyprenyl_synt PF00348.12 KND93463.1 - 4.4e-16 58.5 0.0 2.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KND93463.1 - 2.1e-08 33.7 0.0 6.4e-08 32.1 0.0 1.7 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain ANTAR PF03861.9 KND93463.1 - 0.053 13.1 1.2 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 ANTAR domain LCAT PF02450.10 KND93463.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Coleoptericin PF06286.6 KND93464.1 - 0.066 13.1 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Coleoptericin Ldh_1_C PF02866.13 KND93464.1 - 0.079 12.6 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Phage_tail_2 PF06199.6 KND93464.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.0 1 0 0 1 1 1 0 Phage major tail protein 2 FAD_binding_3 PF01494.14 KND93465.1 - 4.1e-10 39.2 2.3 0.00019 20.6 0.6 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KND93465.1 - 6.5e-07 28.5 0.1 0.006 15.5 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND93465.1 - 1.8e-05 24.6 0.0 5.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND93465.1 - 2.1e-05 23.5 0.6 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KND93465.1 - 6.8e-05 21.5 0.2 0.076 11.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 KND93465.1 - 0.00012 21.0 0.4 0.2 10.5 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KND93465.1 - 0.0017 18.3 0.0 0.0043 16.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KND93465.1 - 0.0055 15.8 0.0 0.16 10.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KND93465.1 - 0.0075 16.3 0.0 0.039 14.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KND93465.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KND93465.1 - 0.046 14.1 0.1 4.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND93465.1 - 0.062 13.0 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NTP_transf_2 PF01909.18 KND93466.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain RNA_pol_Rpc4 PF05132.9 KND93467.1 - 8.7e-25 87.2 1.5 2.2e-24 85.8 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 UreD PF01774.12 KND93468.1 - 8.7e-54 182.1 0.0 1.1e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF1148 PF06618.6 KND93468.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Mito_carr PF00153.22 KND93469.1 - 1.6e-72 239.2 1.4 1.5e-25 88.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KND93469.1 - 4.8e-16 56.7 7.2 1.6e-07 30.1 0.1 5.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KND93469.1 - 1.1e-15 57.5 3.9 4.9e-08 32.9 0.3 3.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KND93469.1 - 4.6e-15 54.9 2.0 0.01 15.4 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 KND93469.1 - 8.8e-15 53.2 4.1 1.3e-06 27.8 0.1 5.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 KND93469.1 - 2.5e-12 45.5 4.3 3.8e-06 25.9 0.2 4.6 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KND93469.1 - 0.16 11.8 0.2 12 5.9 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain Cyclin_N PF00134.18 KND93470.1 - 1.3e-42 144.3 0.2 2.7e-42 143.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KND93470.1 - 7.1e-32 109.8 0.0 1.4e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA-synt_1 PF00133.17 KND93471.1 - 2.7e-51 174.3 0.0 5.6e-28 97.3 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KND93471.1 - 2.1e-39 134.7 0.0 8.9e-39 132.6 0.0 2.1 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KND93471.1 - 8.4e-31 106.9 0.0 4.9e-23 81.4 0.0 4.3 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KND93471.1 - 1.3e-11 44.4 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 KND93471.1 - 0.022 13.6 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 KND93471.1 - 0.06 12.4 0.0 9.8 5.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KND93471.1 - 0.18 10.4 0.0 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 KND93471.1 - 0.21 10.2 0.3 10 4.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PQ-loop PF04193.9 KND93472.1 - 1.2e-32 111.2 9.4 2.8e-16 58.8 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.11 KND93473.1 - 6.3e-30 104.0 44.2 6.3e-30 104.0 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3593 PF12159.3 KND93474.1 - 0.038 13.7 2.5 0.062 13.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Tmemb_170 PF10190.4 KND93474.1 - 0.15 12.1 4.6 0.11 12.6 1.1 2.3 2 0 0 2 2 2 0 Putative transmembrane protein 170 Zn_clus PF00172.13 KND93475.1 - 0.00071 19.4 12.3 0.0012 18.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KND93475.1 - 0.067 12.4 0.1 0.067 12.4 0.0 2.3 2 0 0 2 2 2 0 Histone chaperone domain CHZ Abhydrolase_3 PF07859.8 KND93476.1 - 1.2e-09 38.0 1.1 6.1e-08 32.4 0.8 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND93476.1 - 4.5e-07 29.7 0.4 1.4e-06 28.1 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND93476.1 - 1.9e-05 24.6 4.6 4e-05 23.6 3.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND93476.1 - 0.00022 20.5 0.0 0.0015 17.7 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF3089 PF11288.3 KND93476.1 - 0.0065 15.6 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Thioesterase PF00975.15 KND93476.1 - 0.0065 16.7 0.2 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 KND93476.1 - 0.013 15.0 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KND93476.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.6 KND93476.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) IGR PF09597.5 KND93477.1 - 7.5e-24 83.3 0.0 1.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif DUF4661 PF15576.1 KND93477.1 - 0.049 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) E1-E2_ATPase PF00122.15 KND93478.1 - 4.2e-16 58.6 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND93478.1 - 5.5e-15 56.3 0.0 2.8e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND93478.1 - 1.6e-10 41.4 0.4 4.5e-10 40.0 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND93478.1 - 2.3e-05 24.2 0.1 0.00036 20.4 0.0 2.7 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND93478.1 - 0.00072 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.2 KND93479.1 - 5.8e-93 311.7 0.1 7.7e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KND93479.1 - 9.3e-26 90.1 0.0 1.9e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Glyco_hydro_63 PF03200.11 KND93480.1 - 8.5e-184 612.6 0.0 8.1e-183 609.3 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KND93480.1 - 0.00029 19.6 0.0 0.00049 18.8 0.0 1.3 1 0 0 1 1 1 1 Trehalase DUF3647 PF12363.3 KND93480.1 - 0.14 12.2 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Phage protein TrmE_N PF10396.4 KND93482.1 - 2.8e-23 82.0 0.0 5.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KND93482.1 - 1.8e-19 69.9 0.2 7.5e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KND93482.1 - 1.9e-16 60.0 0.0 4.6e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND93482.1 - 6.4e-05 22.2 0.0 0.00015 21.1 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KND93482.1 - 0.00095 19.0 0.0 0.0063 16.3 0.0 2.1 1 1 0 2 2 2 1 Dynamin family Miro PF08477.8 KND93482.1 - 0.0053 17.2 0.0 0.067 13.6 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KND93482.1 - 0.019 14.1 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2764 PF10962.3 KND93482.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) ABC_tran PF00005.22 KND93482.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Proteasome PF00227.21 KND93483.1 - 4.1e-49 166.4 0.1 5.1e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KND93483.1 - 6.5e-11 41.3 0.2 1.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Hus1 PF04005.7 KND93484.1 - 4.6e-87 291.6 0.0 5.5e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF3977 PF13122.1 KND93485.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3977) FH2 PF02181.18 KND93486.1 - 1e-82 278.0 4.8 1.9e-82 277.0 3.3 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KND93486.1 - 4.4e-63 212.0 0.1 1.7e-62 210.1 0.1 2.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KND93486.1 - 2.8e-52 177.0 4.5 4.7e-52 176.2 1.1 2.9 2 1 1 3 3 3 1 Diaphanous FH3 Domain DUF1777 PF08648.7 KND93487.1 - 1.4e-30 106.3 27.4 1.4e-30 106.3 19.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Peptidase_M19 PF01244.16 KND93488.1 - 3.6e-99 331.7 0.0 4.5e-99 331.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GMC_oxred_N PF00732.14 KND93489.1 - 3.9e-51 173.9 0.0 5.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND93489.1 - 3.2e-36 124.7 0.0 4.9e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND93489.1 - 9.6e-06 24.6 1.0 0.015 14.2 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KND93489.1 - 0.00097 18.1 0.0 0.0021 17.0 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KND93489.1 - 0.0038 16.1 0.1 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND93489.1 - 0.0089 15.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND93489.1 - 0.014 15.4 0.5 0.042 13.8 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND93489.1 - 0.039 13.0 0.6 0.071 12.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 KND93489.1 - 0.099 12.6 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.14 KND93490.1 - 2.6e-145 483.9 0.1 2.6e-100 335.8 0.0 2.1 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.7 KND93490.1 - 2.4e-15 56.1 0.0 5.8e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.11 KND93491.1 - 1.7e-12 46.7 40.3 2e-12 46.5 26.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KND93491.1 - 2.5e-08 33.5 7.9 2.5e-08 33.5 5.5 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Arylesterase PF01731.15 KND93492.1 - 3.3e-05 23.7 0.2 5.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Arylesterase DUF4329 PF14220.1 KND93492.1 - 0.091 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) S1-P1_nuclease PF02265.11 KND93495.1 - 1.6e-72 244.2 0.6 1.8e-72 244.0 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease F-box-like PF12937.2 KND93496.1 - 0.0023 17.5 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.1 KND93497.1 - 1.2e-29 103.3 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND93497.1 - 5e-08 33.0 0.0 5.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND93497.1 - 5.5e-06 26.3 0.0 8.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Amidase PF01425.16 KND93498.1 - 5.9e-94 315.4 0.0 3.3e-92 309.6 0.0 2.0 1 1 0 1 1 1 1 Amidase TauD PF02668.11 KND93499.1 - 7e-44 150.4 0.1 1.1e-43 149.8 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KND93499.1 - 0.00017 21.9 0.3 0.003 17.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF971) Alk_phosphatase PF00245.15 KND93500.1 - 4e-63 213.5 0.0 6.6e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 KND93500.1 - 1.2e-07 31.4 0.4 5.2e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KND93500.1 - 8.8e-07 28.3 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KND93500.1 - 0.0018 16.7 0.3 0.0034 15.8 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KND93500.1 - 0.033 13.0 0.1 0.051 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FTA4 PF13093.1 KND93500.1 - 0.034 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CutC PF03932.9 KND93501.1 - 2.6e-31 108.4 0.1 8e-31 106.8 0.0 1.6 1 1 0 1 1 1 1 CutC family Septin PF00735.13 KND93502.1 - 6.4e-117 389.5 0.3 1e-116 388.9 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KND93502.1 - 3.6e-07 30.1 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KND93502.1 - 5.5e-06 25.6 0.0 1.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KND93502.1 - 7.5e-06 25.4 1.3 5.5e-05 22.6 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KND93502.1 - 0.0016 18.9 0.2 0.0053 17.2 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KND93502.1 - 0.0028 17.2 0.1 0.0057 16.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND93502.1 - 0.003 17.7 0.4 0.013 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 KND93502.1 - 0.0045 16.1 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KND93502.1 - 0.0086 15.5 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 KND93502.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 KND93502.1 - 0.012 14.9 0.6 0.041 13.2 0.4 1.9 2 1 0 2 2 1 0 Ras family ABC_tran PF00005.22 KND93502.1 - 0.018 15.3 0.4 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.7 KND93502.1 - 0.018 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.7 KND93502.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 KND93502.1 - 0.041 12.7 0.5 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 KND93502.1 - 0.047 13.6 1.9 0.34 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain DUF2968 PF11180.3 KND93502.1 - 0.061 12.7 6.3 0.15 11.3 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Dynamin_N PF00350.18 KND93502.1 - 0.078 12.7 7.9 0.59 9.9 0.1 3.1 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 KND93502.1 - 0.082 13.0 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.4 KND93502.1 - 0.11 12.0 1.4 2.7 7.4 0.3 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 KND93502.1 - 0.13 11.2 3.2 0.24 10.3 2.2 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Ribosomal_L6e PF01159.14 KND93502.1 - 0.18 12.0 6.7 2.2 8.5 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e ArgK PF03308.11 KND93502.1 - 0.34 9.6 3.3 5.6 5.6 0.0 3.1 3 0 0 3 3 3 0 ArgK protein Myc-LZ PF02344.10 KND93502.1 - 1.3 8.7 9.0 0.36 10.4 1.6 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 KND93503.1 - 1.4e-49 164.3 34.9 6.4e-10 38.5 0.0 12.5 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 KND93503.1 - 1.3e-27 95.9 0.0 1.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KND93503.1 - 6e-05 22.8 2.1 0.063 12.9 0.1 4.7 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KND93503.1 - 0.001 16.9 0.0 0.0045 14.8 0.0 1.9 2 0 0 2 2 2 1 IKI3 family Nup160 PF11715.3 KND93503.1 - 0.0025 16.0 0.5 0.37 8.8 0.0 3.3 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KND93503.1 - 0.01 14.9 0.1 9.4 5.2 0.0 3.7 3 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KND93503.1 - 0.13 10.9 1.8 11 4.5 0.7 3.6 2 1 0 2 2 2 0 Nup133 N terminal like DUF4243 PF14027.1 KND93504.1 - 3e-80 270.1 5.2 3.7e-80 269.8 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAP PF00956.13 KND93505.1 - 5.6e-44 150.1 13.7 1.3e-43 148.9 9.5 1.5 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4366 PF14283.1 KND93505.1 - 4.6 6.6 16.2 11 5.3 11.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Asparaginase PF00710.15 KND93506.1 - 2.3e-100 335.5 0.0 3e-100 335.1 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KND93506.1 - 6.2e-14 52.0 0.1 1.4e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KND93506.1 - 2.4e-12 45.9 0.1 3.3e-06 26.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KND93506.1 - 2.3e-09 37.5 0.1 3.7e-06 27.2 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93506.1 - 1.2e-07 31.2 0.1 0.00038 20.4 0.0 4.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 KND93506.1 - 3.4e-07 30.3 0.1 3.3e-06 27.1 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) USP7_ICP0_bdg PF12436.3 KND93507.1 - 2.4e-84 282.4 0.1 3.4e-82 275.4 0.1 2.9 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KND93507.1 - 9.3e-70 234.3 13.0 2e-69 233.2 0.8 4.1 5 0 0 5 5 5 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KND93507.1 - 4.3e-56 189.9 3.0 6.7e-56 189.3 2.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND93507.1 - 1.2e-29 103.6 0.7 3.1e-29 102.3 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KND93507.1 - 4.7e-11 42.9 0.6 5e-10 39.6 0.0 3.1 3 2 1 4 4 4 1 MATH domain YukD PF08817.5 KND93507.1 - 0.00039 20.9 0.0 2.1 8.9 0.0 2.9 2 0 0 2 2 2 2 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.4 KND93509.1 - 9.6e-44 148.7 0.1 1.8e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KND93509.1 - 3.8e-11 42.6 0.0 3.6e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KND93509.1 - 0.00056 19.5 0.0 0.00095 18.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KND93509.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.22 KND93510.1 - 0.0027 18.0 0.0 0.0051 17.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AA_permease PF00324.16 KND93511.1 - 1.4e-127 426.0 52.4 2.7e-119 398.6 24.3 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KND93511.1 - 3.1e-26 91.8 51.6 9.6e-25 86.9 35.7 2.2 1 1 0 1 1 1 1 Amino acid permease Acyl-CoA_dh_1 PF00441.19 KND93512.1 - 7.8e-27 94.2 0.3 1.4e-26 93.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KND93512.1 - 1.5e-15 56.4 0.0 3.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KND93512.1 - 2.2e-12 47.5 0.1 4.9e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KND93512.1 - 1.9e-10 41.1 0.2 1.9e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_5 PF12695.2 KND93513.1 - 6.6e-07 29.1 0.2 3e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND93513.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KND93513.1 - 0.029 13.9 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.7 KND93513.1 - 0.045 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase ARL6IP6 PF15062.1 KND93513.1 - 0.1 12.5 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix DUF1769 PF08588.5 KND93514.1 - 7.5e-29 99.4 0.2 1.6e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Peptidase_A4 PF01828.12 KND93515.1 - 3e-27 95.0 0.7 3.9e-27 94.6 0.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Macoilin PF09726.4 KND93517.1 - 0.62 8.2 5.9 0.93 7.6 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Polysacc_synt_4 PF04669.8 KND93518.1 - 4.5e-24 84.8 1.1 2.4e-23 82.5 0.8 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis RRS1 PF04939.7 KND93518.1 - 0.08 12.4 2.6 0.25 10.8 1.2 1.9 1 1 1 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) MFS_1 PF07690.11 KND93520.1 - 3e-23 82.1 27.6 3e-23 82.1 19.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.1 KND93521.1 - 1.9e-22 80.4 0.2 3.7e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KND93521.1 - 2.1e-11 43.4 0.2 5.3e-11 42.1 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND93521.1 - 1.6e-08 34.2 0.1 6.8e-07 29.0 0.0 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain YjeF_N PF03853.10 KND93521.1 - 0.069 12.7 0.3 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus Metallophos PF00149.23 KND93523.1 - 5.7e-39 133.5 0.1 1.4e-38 132.3 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KND93523.1 - 3.1e-31 107.2 0.9 7.7e-31 105.9 0.6 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KND93523.1 - 6.7e-21 73.7 2.9 2e-14 52.9 0.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KND93523.1 - 1.6e-18 65.4 1.0 1.5e-05 24.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND93523.1 - 1.9e-13 49.2 0.6 0.0024 17.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND93523.1 - 7.5e-06 26.4 1.5 0.0033 18.0 0.2 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND93523.1 - 1.2e-05 25.1 0.9 0.27 11.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KND93523.1 - 6.4e-05 23.2 0.1 0.014 15.6 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND93523.1 - 8.7e-05 22.8 0.5 1.3 9.8 0.0 3.8 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND93523.1 - 0.00021 21.0 0.1 0.0013 18.5 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND93523.1 - 0.0099 15.5 0.2 5.5 7.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 KND93523.1 - 0.024 13.6 0.1 0.18 10.8 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KND93523.1 - 0.069 13.2 0.2 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 KND93523.1 - 0.11 11.7 0.0 20 4.5 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR Kin17_mid PF10357.4 KND93525.1 - 1.8e-50 169.7 0.8 1.8e-50 169.7 0.6 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KND93525.1 - 0.00011 22.2 2.2 0.00011 22.2 1.5 2.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND93525.1 - 0.00036 20.6 3.1 0.00036 20.6 2.1 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KND93525.1 - 0.0065 16.5 2.3 0.0085 16.1 0.2 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Spt4 PF06093.8 KND93526.1 - 3.6e-32 110.0 0.2 4.5e-32 109.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Cys_rich_CPXG PF14255.1 KND93526.1 - 0.4 10.5 3.8 15 5.4 0.0 2.6 2 1 0 2 2 2 0 Cysteine-rich CPXCG Serglycin PF04360.7 KND93527.1 - 0.028 14.1 1.5 0.027 14.2 1.1 1.1 1 0 0 1 1 1 0 Serglycin DUF572 PF04502.8 KND93528.1 - 1e-69 235.2 10.2 1.2e-69 234.9 7.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KND93528.1 - 0.0028 17.5 0.5 0.009 15.8 0.3 1.8 1 1 0 1 1 1 1 Benyvirus 14KDa protein RNA_pol_N PF01194.12 KND93528.1 - 0.019 14.9 0.6 1.3 9.0 0.0 3.0 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit DUF951 PF06107.6 KND93528.1 - 3.3 7.2 5.4 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) Methyltransf_11 PF08241.7 KND93529.1 - 0.047 14.1 0.0 0.05 14.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FAM177 PF14774.1 KND93529.1 - 0.11 12.3 0.2 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 FAM177 family Pyr_redox_2 PF07992.9 KND93530.1 - 1.9e-12 47.4 0.0 1e-10 41.8 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND93530.1 - 3e-10 40.3 1.0 6.7e-10 39.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND93530.1 - 4.9e-06 25.6 0.4 0.01 14.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KND93530.1 - 5.2e-05 23.4 1.6 0.023 14.7 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND93530.1 - 0.071 11.9 2.0 3.8 6.3 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Es2 PF09751.4 KND93531.1 - 4.8e-86 289.7 4.2 1.1e-85 288.5 2.9 1.7 1 1 0 1 1 1 1 Nuclear protein Es2 ABC1 PF03109.11 KND93531.1 - 7e-33 113.1 0.0 1.4e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Arch_flagellin PF01917.11 KND93531.1 - 0.025 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Archaebacterial flagellin DUF947 PF06102.7 KND93532.1 - 1.2e-54 184.6 28.5 1.2e-54 184.6 19.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF947) MIF4G_like PF09088.6 KND93533.1 - 1.3e-70 236.7 0.0 2.4e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KND93533.1 - 5.2e-47 160.1 0.0 7.6e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KND93533.1 - 0.013 14.9 0.0 0.071 12.5 0.0 2.1 2 0 0 2 2 2 0 MIF4G domain Patatin PF01734.17 KND93534.1 - 3.3e-21 76.1 0.1 2.8e-20 73.1 0.0 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_12 PF13424.1 KND93534.1 - 4e-18 65.1 0.3 1.2e-10 41.1 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KND93534.1 - 2.5e-14 52.6 2.3 0.00017 21.4 0.1 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 KND93534.1 - 5.5e-12 45.1 0.1 1.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 KND93534.1 - 1.4e-05 25.5 0.8 0.19 12.4 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND93534.1 - 1.6e-05 25.1 0.2 0.42 11.3 0.0 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KND93534.1 - 4.2e-05 23.5 0.0 0.0076 16.3 0.0 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KND93534.1 - 6.4e-05 23.2 4.1 0.14 12.5 0.1 3.5 2 1 2 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KND93534.1 - 9e-05 22.6 0.0 0.00044 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.1 KND93534.1 - 9.6e-05 21.9 0.3 1.2 9.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.7 KND93534.1 - 0.00033 20.3 0.0 0.00073 19.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.1 KND93534.1 - 0.00037 20.7 0.3 3.6 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND93534.1 - 0.0022 17.7 0.0 0.69 9.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KND93534.1 - 0.0026 17.8 1.4 1 9.5 0.0 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat PPR PF01535.15 KND93534.1 - 0.0086 15.9 0.0 15 5.8 0.0 3.7 3 0 0 3 3 3 0 PPR repeat TPR_11 PF13414.1 KND93534.1 - 0.013 15.0 0.1 11 5.8 0.0 2.9 2 1 0 3 3 3 0 TPR repeat SRP54 PF00448.17 KND93534.1 - 0.033 13.6 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TPR_8 PF13181.1 KND93534.1 - 0.065 13.0 0.0 1.2 9.0 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR_1 PF12854.2 KND93534.1 - 0.12 11.8 0.1 17 5.0 0.0 2.6 2 0 0 2 2 2 0 PPR repeat CAF1A PF12253.3 KND93535.1 - 3.2e-17 62.3 3.4 3.2e-17 62.3 2.4 2.6 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KND93535.1 - 1.9e-14 53.5 47.7 4.1e-14 52.4 33.0 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 KND93535.1 - 0.00077 18.8 46.3 0.00077 18.8 32.1 1.8 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 TFIIA PF03153.8 KND93535.1 - 0.64 9.8 28.6 1.5 8.6 19.8 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 KND93535.1 - 7.6 4.1 18.4 11 3.5 12.7 1.3 1 0 0 1 1 1 0 Ycf1 AvrE PF11725.3 KND93535.1 - 9.5 3.0 24.4 13 2.6 16.9 1.1 1 0 0 1 1 1 0 Pathogenicity factor RCC1 PF00415.13 KND93536.1 - 0.17 12.1 0.3 28 5.0 0.1 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.20 KND93537.1 - 5.1e-43 147.0 0.0 7.2e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93537.1 - 2.6e-26 92.2 0.0 3.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KND93537.1 - 1e-06 28.7 0.1 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KND93537.1 - 0.00064 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND93537.1 - 0.013 15.2 0.1 0.13 11.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PhnH PF05845.7 KND93538.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) DUF4190 PF13828.1 KND93539.1 - 0.047 13.2 0.0 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) SKG6 PF08693.5 KND93539.1 - 0.28 10.5 2.6 0.54 9.6 1.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cupin_8 PF13621.1 KND93540.1 - 3e-11 43.3 0.0 3.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain DUF2826 PF11442.3 KND93540.1 - 0.027 14.1 0.1 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) NPCC PF08058.6 KND93541.1 - 1.4e-28 99.5 0.1 9.7e-28 96.8 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore complex component ERG2_Sigma1R PF04622.7 KND93543.1 - 5e-92 307.0 0.0 5.8e-92 306.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NmrA PF05368.8 KND93544.1 - 3e-75 252.4 0.0 3.7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF2498 PF10692.4 KND93544.1 - 0.035 13.6 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2498) NAD_binding_10 PF13460.1 KND93544.1 - 0.043 13.8 0.4 0.66 9.9 0.3 2.2 1 1 0 1 1 1 0 NADH(P)-binding Fcf1 PF04900.7 KND93545.1 - 7e-36 122.3 0.2 2.4e-35 120.6 0.1 1.9 2 0 0 2 2 2 1 Fcf1 Fungal_trans PF04082.13 KND93545.1 - 3.8e-12 45.6 0.8 6.2e-12 44.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93545.1 - 3.4e-06 26.8 10.0 6.9e-06 25.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4080 PF13311.1 KND93545.1 - 0.057 13.4 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Rep_fac_C PF08542.6 KND93546.1 - 6.2e-19 67.7 0.0 1.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KND93546.1 - 9.4e-12 44.8 0.0 7.4e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KND93546.1 - 2.1e-11 44.1 0.0 4.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KND93546.1 - 4.7e-07 29.7 0.0 9.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND93546.1 - 5.6e-06 26.4 0.1 0.00023 21.2 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 KND93546.1 - 7.2e-06 25.2 0.0 2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KND93546.1 - 3.9e-05 23.7 0.2 0.11 12.6 0.1 2.8 2 1 1 3 3 2 2 AAA domain Rad17 PF03215.10 KND93546.1 - 5.2e-05 22.1 0.0 0.013 14.1 0.0 2.4 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KND93546.1 - 0.0001 21.7 0.1 0.048 13.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KND93546.1 - 0.00017 21.1 0.1 0.034 13.5 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_3 PF07726.6 KND93546.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KND93546.1 - 0.00023 20.7 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KND93546.1 - 0.0023 17.4 0.1 0.15 11.5 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 KND93546.1 - 0.0041 16.3 0.1 0.041 13.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 KND93546.1 - 0.0048 16.4 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 KND93546.1 - 0.0075 16.0 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 KND93546.1 - 0.008 14.9 0.1 0.025 13.3 0.0 1.6 1 1 1 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 KND93546.1 - 0.009 15.5 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_11 PF13086.1 KND93546.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND93546.1 - 0.014 15.1 0.7 0.06 13.0 0.1 2.2 2 1 1 3 3 3 0 NTPase AAA_5 PF07728.9 KND93546.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.9 3 0 0 3 3 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.5 KND93546.1 - 0.019 14.2 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KND93546.1 - 0.033 14.4 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KND93546.1 - 0.035 14.0 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KND93546.1 - 0.071 11.9 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DNA_pol3_gamma3 PF12169.3 KND93546.1 - 0.074 12.8 0.2 0.82 9.4 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DER1 PF04511.10 KND93548.1 - 1.8e-25 89.6 4.9 2.1e-25 89.4 3.4 1.0 1 0 0 1 1 1 1 Der1-like family NAP PF00956.13 KND93549.1 - 8.2e-86 287.0 4.8 8.2e-86 287.0 3.3 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF3812 PF12757.2 KND93550.1 - 5.3e-39 133.0 13.8 5.3e-39 133.0 9.6 5.0 3 2 1 4 4 4 1 Protein of unknown function (DUF3812) Cytochrom_C1 PF02167.10 KND93550.1 - 7.7 6.0 14.4 0.08 12.5 1.0 2.8 2 0 0 2 2 2 0 Cytochrome C1 family Y_phosphatase3 PF13350.1 KND93551.1 - 8.6e-30 104.1 0.9 4e-28 98.7 0.6 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KND93551.1 - 3.8e-06 26.9 0.2 7.3e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KND93551.1 - 1.3e-05 24.6 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.9 KND93551.1 - 0.01 14.6 0.2 0.038 12.7 0.0 1.7 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KND93551.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KND93551.1 - 0.1 12.1 0.1 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Pkinase PF00069.20 KND93552.1 - 1.4e-63 214.5 0.0 1.8e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93552.1 - 6e-34 117.2 0.0 8.8e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93552.1 - 0.0037 16.2 0.0 0.0077 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Frag1 PF10277.4 KND93553.1 - 5.4e-43 146.9 16.2 6.2e-43 146.7 11.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Arif-1 PF06770.6 KND93553.1 - 0.76 9.1 6.1 1.5 8.1 4.3 1.5 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) ABC_tran PF00005.22 KND93554.1 - 2.2e-10 40.9 0.0 7.3e-10 39.2 0.0 1.9 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.1 KND93554.1 - 0.00022 21.6 0.0 0.00033 21.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KND93554.1 - 0.0035 16.6 0.0 0.99 8.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KND93554.1 - 0.013 15.2 0.1 0.06 13.1 0.1 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KND93554.1 - 0.019 14.9 0.1 0.05 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KND93554.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KND93554.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KND93554.1 - 0.076 12.4 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF4231 PF14015.1 KND93555.1 - 5.9 6.9 6.2 29 4.6 4.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Methyltransf_12 PF08242.7 KND93556.1 - 1.4e-14 54.3 0.1 4.5e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND93556.1 - 7.9e-13 48.7 0.0 1.8e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND93556.1 - 4.7e-10 39.7 0.0 9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND93556.1 - 5.1e-10 39.2 0.0 1.1e-09 38.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND93556.1 - 4.1e-09 36.1 0.0 1.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND93556.1 - 2.9e-08 34.2 0.0 8.8e-08 32.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND93556.1 - 5.6e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND93556.1 - 6.1e-07 28.7 0.0 9.7e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KND93556.1 - 1.3e-05 24.8 0.0 0.00043 19.9 0.0 2.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.1 KND93556.1 - 0.00013 22.7 0.1 0.00067 20.4 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 KND93556.1 - 0.00043 19.6 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KND93556.1 - 0.00057 18.9 0.0 0.39 9.6 0.0 2.2 1 1 0 2 2 2 2 NNMT/PNMT/TEMT family DUF3419 PF11899.3 KND93556.1 - 0.0064 15.2 0.2 0.014 14.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) FmrO PF07091.6 KND93556.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_16 PF10294.4 KND93556.1 - 0.016 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_20 PF12147.3 KND93556.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 KND93556.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4243 PF14027.1 KND93558.1 - 7.4e-80 268.8 3.7 9.6e-80 268.4 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Lipase_GDSL_2 PF13472.1 KND93559.1 - 3.2e-09 37.1 0.3 6.1e-09 36.2 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KND93559.1 - 2e-05 24.5 0.1 5.7e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KND93559.1 - 0.005 16.5 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1996 PF09362.5 KND93560.1 - 2.3e-78 263.0 0.7 3.3e-78 262.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.13 KND93561.1 - 1.4e-10 40.5 0.4 2.4e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93561.1 - 5.8e-05 22.9 7.3 5.8e-05 22.9 5.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 KND93562.1 - 3.2e-57 194.0 1.8 4.1e-57 193.7 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KND93562.1 - 1.5e-05 25.2 0.3 0.0066 16.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND93562.1 - 3.9e-05 23.5 0.2 0.0001 22.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KND93562.1 - 0.0021 18.1 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 KND93562.1 - 0.0073 15.4 0.2 1.7 7.6 0.1 2.1 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.9 KND93562.1 - 0.011 14.4 0.1 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.10 KND93562.1 - 0.025 12.7 0.0 3.9 5.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 KND93562.1 - 0.058 13.2 0.4 0.95 9.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND93562.1 - 0.061 12.1 2.6 0.11 11.3 1.8 1.4 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KND93562.1 - 0.12 11.4 0.2 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KND93562.1 - 0.13 12.0 0.4 0.43 10.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HAD_2 PF13419.1 KND93563.1 - 1.6e-17 64.3 0.0 2.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND93563.1 - 5.4e-08 32.4 0.2 9.7e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KND93563.1 - 7.4e-05 23.2 0.1 0.00021 21.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KND93563.1 - 0.00014 21.5 0.0 0.031 13.9 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Init_tRNA_PT PF04179.7 KND93564.1 - 1.4e-76 258.1 0.0 2.8e-76 257.2 0.0 1.4 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase MARVEL PF01284.18 KND93565.1 - 0.00026 20.8 16.0 0.00043 20.1 11.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 KND93566.1 - 5.3e-42 143.7 42.1 5.3e-42 143.7 29.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93566.1 - 1.2e-16 60.3 9.1 1.2e-16 60.3 6.3 3.6 2 1 2 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 KND93566.1 - 8e-07 27.6 17.6 3.9e-06 25.3 11.0 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyoxalase_2 PF12681.2 KND93567.1 - 1.3e-16 61.1 0.1 1.5e-16 60.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KND93567.1 - 1.5e-10 41.1 0.0 3e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KND93567.1 - 0.022 14.7 0.0 0.025 14.5 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CBS PF00571.23 KND93567.1 - 0.091 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 CBS domain bZIP_1 PF00170.16 KND93568.1 - 0.0018 18.2 6.4 0.0037 17.2 4.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND93568.1 - 0.0043 16.8 10.9 0.0091 15.7 7.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF4603 PF15376.1 KND93568.1 - 0.45 7.6 8.8 0.59 7.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CDC45 PF02724.9 KND93568.1 - 1.5 6.7 11.6 1.9 6.4 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.20 KND93569.1 - 4.8e-17 62.3 0.3 7.8e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND93569.1 - 7.8e-08 32.1 0.2 1.2e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Med5 PF08689.5 KND93570.1 - 6.6e-226 752.3 0.0 9e-226 751.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF2593 PF10767.4 KND93570.1 - 0.095 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) TRAP_alpha PF03896.11 KND93571.1 - 2.1e-10 40.0 0.0 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.18 KND93572.1 - 2.6e-52 177.4 0.0 6.2e-52 176.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KND93572.1 - 1.5e-07 31.0 12.1 1.5e-07 31.0 8.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND93572.1 - 2.4e-07 30.3 8.9 2.4e-07 30.3 6.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND93572.1 - 1.4e-06 28.2 13.1 9.5e-06 25.5 8.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND93572.1 - 7.5e-06 25.5 10.9 7.5e-06 25.5 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND93572.1 - 2.6e-05 24.2 5.8 5.9e-05 23.0 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KND93572.1 - 7.1e-05 22.4 11.2 7.1e-05 22.4 7.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 KND93572.1 - 0.03 13.9 3.5 0.082 12.5 2.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KND93572.1 - 0.1 12.3 5.8 0.15 11.8 2.6 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.9 KND93572.1 - 0.13 11.7 7.8 1 8.8 5.4 2.3 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 KND93572.1 - 0.27 10.7 6.9 0.6 9.6 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KND93572.1 - 0.38 10.6 13.0 0.73 9.7 7.2 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CN_hydrolase PF00795.17 KND93573.1 - 7.9e-11 41.6 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCC2_GCC3 PF07699.8 KND93574.1 - 0.039 13.5 0.6 0.11 12.1 0.4 1.7 1 0 0 1 1 1 0 GCC2 and GCC3 DKCLD PF08068.7 KND93575.1 - 5.9e-31 106.1 0.4 5.8e-30 103.0 0.1 2.6 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 KND93575.1 - 1.3e-24 87.0 0.2 1e-21 77.6 0.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KND93575.1 - 1.6e-20 72.5 0.5 2.8e-20 71.8 0.3 1.4 1 0 0 1 1 1 1 PUA domain Sec2p PF06428.6 KND93577.1 - 2.4e-10 40.1 11.8 3.8e-10 39.4 4.5 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 KND93577.1 - 7.1e-05 22.4 9.9 0.064 12.8 0.0 2.1 2 0 0 2 2 2 2 IncA protein HR1 PF02185.11 KND93577.1 - 0.0067 16.1 4.9 0.24 11.1 0.4 2.6 2 0 0 2 2 2 1 Hr1 repeat Jnk-SapK_ap_N PF09744.4 KND93577.1 - 0.036 14.0 10.3 1.2 9.1 3.4 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GOLGA2L5 PF15070.1 KND93577.1 - 0.043 12.3 10.3 0.039 12.4 1.2 2.1 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 SlyX PF04102.7 KND93577.1 - 0.14 12.5 9.0 1.6 9.1 0.7 3.0 2 1 1 3 3 3 0 SlyX DUF2076 PF09849.4 KND93577.1 - 0.2 11.6 4.3 0.38 10.7 3.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Herpes_U30 PF04523.8 KND93577.1 - 0.21 9.0 3.5 2.1 5.7 0.3 2.1 2 0 0 2 2 2 0 Herpes virus tegument protein U30 Atg14 PF10186.4 KND93577.1 - 0.5 9.2 9.3 0.22 10.3 0.1 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 OCD_Mu_crystall PF02423.10 KND93577.1 - 0.51 9.0 4.8 0.19 10.4 1.7 1.4 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Rad50_zn_hook PF04423.9 KND93577.1 - 0.69 9.4 2.7 0.92 9.0 0.4 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif FlxA PF14282.1 KND93577.1 - 0.88 9.5 6.4 1.4 8.8 4.1 1.7 1 1 0 1 1 1 0 FlxA-like protein MbeD_MobD PF04899.7 KND93577.1 - 2 8.3 8.3 4.6 7.2 0.5 2.7 2 1 1 3 3 3 0 MbeD/MobD like Spc7 PF08317.6 KND93577.1 - 2.7 6.5 5.8 4.6 5.8 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CASP_C PF08172.7 KND93577.1 - 3.4 6.6 10.4 1 8.3 1.0 2.4 2 1 0 2 2 2 0 CASP C terminal DUF972 PF06156.8 KND93577.1 - 4.1 7.7 7.1 3.1 8.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4337 PF14235.1 KND93577.1 - 4.5 7.0 13.0 1.2 8.9 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DivIC PF04977.10 KND93577.1 - 5.7 6.4 11.1 0.13 11.7 1.9 2.3 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 KND93577.1 - 6.4 6.3 11.5 1.3 8.6 0.4 2.1 2 0 0 2 2 2 0 Mnd1 family ADIP PF11559.3 KND93577.1 - 7.2 6.5 13.7 0.92 9.3 0.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3138 PF11336.3 KND93577.1 - 7.5 4.5 7.2 11 4.0 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TruB_N PF01509.13 KND93578.1 - 1.3e-43 148.6 0.0 3e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UCH_1 PF13423.1 KND93579.1 - 3.7e-77 259.6 0.0 6.2e-77 258.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fes1 PF08609.5 KND93580.1 - 6.2e-30 103.5 1.5 6.2e-30 103.5 1.1 2.3 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.1 KND93580.1 - 6.3e-08 32.8 0.5 0.00012 22.4 0.0 3.1 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 KND93580.1 - 1.1e-07 31.3 0.0 0.0096 15.7 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KND93580.1 - 2.8e-06 27.5 0.2 6e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KND93580.1 - 0.00072 19.4 0.2 0.21 11.7 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat 6PF2K PF01591.13 KND93581.1 - 8e-58 195.1 0.0 1.1e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KND93581.1 - 6e-23 81.6 1.5 9.6e-23 81.0 1.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KND93581.1 - 2.4e-06 28.3 0.1 0.0053 17.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KND93581.1 - 0.00018 21.4 0.0 0.0036 17.1 0.0 2.4 1 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KND93581.1 - 0.025 13.7 0.0 0.076 12.2 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 KND93581.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TroA PF01297.12 KND93581.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Periplasmic solute binding protein family AAA_18 PF13238.1 KND93581.1 - 0.078 13.2 0.0 21 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Porin_3 PF01459.17 KND93582.1 - 7e-84 281.3 0.0 8.1e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.20 KND93583.1 - 1.5e-63 214.3 0.0 1.8e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93583.1 - 1.9e-25 89.4 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93583.1 - 9.4e-08 31.3 0.0 4.8e-07 29.0 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KND93583.1 - 0.0025 17.6 0.3 0.013 15.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KND93583.1 - 0.077 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KND93583.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DNMT1-RFD PF12047.3 KND93585.1 - 0.00096 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MFS_1 PF07690.11 KND93588.1 - 3e-30 105.1 35.5 5e-23 81.3 18.9 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Abhydrolase_2 PF02230.11 KND93590.1 - 1.4e-26 93.2 0.0 9.7e-25 87.2 0.0 2.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KND93590.1 - 4.7e-06 26.6 3.8 0.00034 20.5 2.6 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND93590.1 - 1.1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND93590.1 - 7.2e-05 22.0 0.0 0.00035 19.8 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KND93590.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KND93590.1 - 0.01 15.3 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.9 KND93590.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Pyridox_oxase_2 PF12766.2 KND93591.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SEP PF08059.8 KND93594.1 - 3.4e-25 88.1 0.0 5.8e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KND93594.1 - 5e-10 39.3 0.0 8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KND93594.1 - 5.1e-10 38.7 0.3 8.1e-10 38.0 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain Sporozoite_P67 PF05642.6 KND93594.1 - 0.016 13.1 2.1 0.023 12.5 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 KND93595.1 - 2.2e-08 33.5 0.0 4.3e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 KND93595.1 - 0.00054 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_Tyr PF07714.12 KND93595.1 - 0.00068 18.7 0.0 0.00098 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND93595.1 - 0.0051 16.5 0.1 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND93595.1 - 0.0097 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CHAD PF05235.9 KND93595.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 CHAD domain WD40 PF00400.27 KND93596.1 - 1.6e-08 34.0 2.1 0.058 13.2 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat TFIIF_alpha PF05793.7 KND93596.1 - 0.0045 15.4 17.7 0.0059 15.0 12.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.7 KND93596.1 - 0.033 13.3 9.1 0.047 12.8 6.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nup160 PF11715.3 KND93596.1 - 0.064 11.3 0.0 0.097 10.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CDC45 PF02724.9 KND93596.1 - 0.069 11.1 13.3 0.093 10.7 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KND93596.1 - 0.16 9.8 14.7 0.21 9.4 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KND93596.1 - 4.5 6.5 11.2 6.8 6.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cwf_Cwc_15 PF04889.7 KND93596.1 - 6.1 6.4 15.3 9 5.9 10.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Xan_ur_permease PF00860.15 KND93597.1 - 5.5e-62 209.4 29.3 2.1e-59 200.9 20.3 2.1 1 1 0 1 1 1 1 Permease family GDPD PF03009.12 KND93598.1 - 2e-12 47.1 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Glyco_hydro_18 PF00704.23 KND93599.1 - 1.9e-43 149.2 0.0 2.3e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Oxidored_molyb PF00174.14 KND93600.1 - 5.6e-54 182.0 0.0 8.3e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KND93600.1 - 7e-23 80.6 0.3 5.8e-12 45.3 0.0 3.3 2 1 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KND93600.1 - 9.8e-13 47.7 0.1 1.9e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain mRNA_triPase PF02940.10 KND93602.1 - 5e-51 173.5 0.0 8.3e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 KND93603.1 - 6.9e-42 139.3 13.0 8.9e-09 35.1 0.0 9.5 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KND93603.1 - 7.7e-19 67.7 0.1 4.2e-12 46.1 0.0 5.3 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 KND93603.1 - 9.9e-09 34.5 2.4 1.7 8.9 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KND93603.1 - 1e-06 29.0 4.2 0.00056 20.3 0.0 5.6 5 2 1 6 6 6 1 HEAT-like repeat DUF1546 PF07571.8 KND93603.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Ribosomal_S13 PF00416.17 KND93604.1 - 2.7e-21 75.9 0.1 3.3e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 RhoGAP PF00620.22 KND93605.1 - 2e-15 56.7 0.0 4.9e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 KND93605.1 - 4e-12 45.7 0.0 7.5e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 KND93605.1 - 0.067 13.0 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 0 KIP1-like protein LTV PF04180.9 KND93606.1 - 1.1e-106 357.8 16.3 1.3e-106 357.6 11.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein ATP-synt_S1 PF05827.7 KND93607.1 - 8e-38 130.3 0.1 6.8e-37 127.3 0.1 1.9 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Ctr PF04145.10 KND93607.1 - 0.026 14.5 0.0 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 Ctr copper transporter family Trm112p PF03966.11 KND93608.1 - 9.6e-16 57.9 0.1 1.2e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 KND93608.1 - 0.043 14.0 0.2 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 KND93608.1 - 0.077 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF1451 PF07295.6 KND93608.1 - 0.22 11.2 0.9 0.43 10.3 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Pro_isomerase PF00160.16 KND93609.1 - 1.2e-46 158.7 1.4 1.4e-46 158.5 1.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAC3_GANP PF03399.11 KND93610.1 - 4.9e-33 114.4 0.0 8.2e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family EMP24_GP25L PF01105.19 KND93611.1 - 8.1e-46 156.0 1.8 9.6e-46 155.7 1.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_C36 PF05415.6 KND93611.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase DUF4433 PF14487.1 KND93611.1 - 0.21 11.2 1.2 8 6.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4433) SKIP_SNW PF02731.10 KND93612.1 - 1.4e-63 213.0 8.8 1.4e-63 213.0 6.1 2.8 3 0 0 3 3 3 1 SKIP/SNW domain Sulfatase PF00884.18 KND93613.1 - 1.8e-74 250.6 0.0 2.4e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KND93613.1 - 0.016 14.5 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KND93613.1 - 0.022 15.0 0.1 0.78 10.0 0.1 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1289 PF06945.8 KND93613.1 - 0.24 10.8 1.1 0.35 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF229 PF02995.12 KND93613.1 - 0.28 9.5 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PhoD PF09423.5 KND93614.1 - 1.2e-60 205.3 0.0 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase DUF1772 PF08592.6 KND93616.1 - 3.2e-08 33.4 1.4 3.3e-08 33.3 0.2 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Rrp15p PF07890.7 KND93617.1 - 6.1e-35 120.1 10.7 6.1e-35 120.1 7.4 2.2 2 1 0 2 2 2 1 Rrp15p Nop14 PF04147.7 KND93617.1 - 1.5 6.6 36.0 2.6 5.8 24.9 1.3 1 1 0 1 1 1 0 Nop14-like family Lactamase_B PF00753.22 KND93618.1 - 1.8e-25 89.7 1.3 1.3e-24 86.9 0.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND93618.1 - 9.1e-06 25.3 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 KND93618.1 - 0.076 12.2 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1236 PF06823.7 KND93618.1 - 0.11 12.2 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Las1 PF04031.8 KND93619.1 - 1.8e-56 190.0 1.6 1.8e-56 190.0 1.1 1.4 2 0 0 2 2 2 1 Las1-like PfkB PF00294.19 KND93621.1 - 2.7e-09 36.5 0.0 1.5e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase NAD_kinase PF01513.16 KND93622.1 - 2.5e-67 226.6 0.0 3.9e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase EBP PF05241.7 KND93623.1 - 8.7e-71 236.9 7.4 1.1e-70 236.6 5.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2823 PF11034.3 KND93624.1 - 2.7e-34 117.0 10.6 3e-34 116.9 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Romo1 PF10247.4 KND93625.1 - 0.04 14.1 0.7 3.6 7.8 0.1 2.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 PAP2 PF01569.16 KND93626.1 - 4.3e-13 49.0 3.0 4.3e-13 49.0 2.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KND93626.1 - 0.048 13.3 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family SNARE_assoc PF09335.6 KND93626.1 - 0.06 13.5 1.6 9 6.5 0.1 2.4 2 0 0 2 2 2 0 SNARE associated Golgi protein DUF2909 PF11137.3 KND93626.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) GTP_EFTU PF00009.22 KND93628.1 - 2.2e-59 200.0 0.2 3e-59 199.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KND93628.1 - 3.7e-25 87.9 0.0 7.8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KND93628.1 - 7.9e-16 57.9 3.3 4.4e-15 55.5 2.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND93628.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND93628.1 - 0.0035 17.8 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KND93628.1 - 0.08 12.4 0.1 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PGA2 PF07543.7 KND93629.1 - 3.6e-35 120.7 3.5 4.9e-35 120.3 2.5 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF3169 PF11368.3 KND93629.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) CLPTM1 PF05602.7 KND93631.1 - 4.7e-148 493.5 0.0 6.2e-148 493.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1673 PF07895.6 KND93631.1 - 0.15 11.5 4.1 0.26 10.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Longin PF13774.1 KND93632.1 - 1.2e-27 95.3 0.1 1.9e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KND93632.1 - 3.3e-16 58.6 0.0 5.9e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 KND93632.1 - 0.0042 16.8 0.8 0.039 13.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Acyl-CoA_dh_C PF12806.2 KND93632.1 - 0.023 14.5 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DUF4404 PF14357.1 KND93632.1 - 0.047 14.0 4.3 2.5 8.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) HSCB_C PF07743.8 KND93632.1 - 0.12 12.8 1.6 4 7.9 0.1 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain APH PF01636.18 KND93633.1 - 3.9e-13 49.6 5.5 7.5e-13 48.7 3.8 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND93633.1 - 5.1e-07 29.4 0.0 6.9e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KND93633.1 - 6.1e-05 22.2 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 KND93633.1 - 0.0021 17.4 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 RIO1 family HTH_Crp_2 PF13545.1 KND93633.1 - 0.077 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Pkinase_Tyr PF07714.12 KND93633.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.2 KND93634.1 - 1.3e-11 44.6 0.0 1.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND93634.1 - 6.5e-10 39.2 0.0 2.2e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND93634.1 - 1.4e-07 31.5 0.0 9.6e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KND93634.1 - 3.1e-07 29.8 0.1 9.4e-05 22.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KND93634.1 - 2.3e-05 24.1 0.0 0.038 14.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat DNA_Packaging_2 PF11123.3 KND93634.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 3 0 0 3 3 3 0 DNA packaging protein LAGLIDADG_WhiA PF14527.1 KND93634.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain IGPD PF00475.13 KND93636.1 - 5.8e-54 181.9 0.3 8.3e-44 148.9 0.0 2.1 2 0 0 2 2 2 2 Imidazoleglycerol-phosphate dehydratase ArgJ PF01960.13 KND93637.1 - 9.4e-144 478.5 0.0 1.1e-143 478.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family IF-2B PF01008.12 KND93638.1 - 3.3e-48 164.1 0.5 1e-47 162.5 0.3 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF3684 PF12449.3 KND93640.1 - 0 1341.2 0.0 0 1340.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KND93640.1 - 1.7e-05 24.4 0.0 4.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.1 KND93640.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 MMtag PF10159.4 KND93641.1 - 7.1e-31 106.0 4.5 1.6e-30 104.9 3.1 1.6 1 0 0 1 1 1 1 Kinase phosphorylation protein Daxx PF03344.10 KND93641.1 - 6.6 5.0 10.2 7.7 4.8 7.1 1.0 1 0 0 1 1 1 0 Daxx Family Med6 PF04934.9 KND93642.1 - 3.2e-40 136.9 0.0 4.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Glyco_hydro_31 PF01055.21 KND93643.1 - 7.3e-150 499.6 5.5 9.4e-150 499.2 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KND93643.1 - 2.1e-25 88.3 0.6 6.2e-25 86.8 0.2 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like RskA PF10099.4 KND93644.1 - 0.02 14.6 0.4 0.022 14.4 0.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RNA_polI_A34 PF08208.6 KND93644.1 - 0.029 14.0 0.3 0.035 13.7 0.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FLILHELTA PF10306.4 KND93645.1 - 1.1e-26 92.6 0.3 1.7e-26 92.0 0.2 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KND93645.1 - 0.027 14.7 0.3 0.041 14.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) NDK PF00334.14 KND93646.1 - 2.3e-54 182.8 0.0 2.9e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_M18 PF02127.10 KND93650.1 - 1.8e-125 418.8 0.0 2.1e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Tim17 PF02466.14 KND93651.1 - 2.1e-48 163.5 10.3 2.6e-48 163.2 7.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KND93651.1 - 0.015 15.2 0.2 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DLH PF01738.13 KND93651.1 - 0.023 13.9 0.1 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family ATP-synt_ab PF00006.20 KND93652.1 - 1.2e-111 371.4 0.0 1.6e-111 370.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KND93652.1 - 4.5e-17 62.5 0.8 7.9e-17 61.7 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KND93652.1 - 2.9e-09 37.0 3.0 1.2e-08 34.9 1.6 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF605 PF04652.11 KND93652.1 - 4.4 6.5 25.3 7.1 5.9 17.5 1.2 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 KND93653.1 - 7.4e-249 828.0 0.0 3.4e-248 825.8 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KND93653.1 - 9.3e-72 242.1 0.0 1.4e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Neurochondrin PF05536.6 KND93653.1 - 0.085 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Neurochondrin ACT_7 PF13840.1 KND93654.1 - 3.1e-22 77.8 0.1 6.9e-17 60.7 0.0 2.4 2 0 0 2 2 2 2 ACT domain UPF0029 PF01205.14 KND93655.1 - 2.4e-29 101.2 0.1 3.9e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KND93655.1 - 0.00075 19.3 0.0 0.0027 17.6 0.0 1.9 1 1 0 1 1 1 1 RWD domain Syntaxin-6_N PF09177.6 KND93656.1 - 1.4e-24 86.2 0.3 1.8e-23 82.7 0.0 2.5 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 KND93656.1 - 8.4e-14 51.0 7.9 8.4e-14 51.0 5.5 2.8 3 0 0 3 3 3 1 SNARE domain DUF869 PF05911.6 KND93656.1 - 0.0013 17.1 0.3 0.0031 15.8 0.2 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF869) OmpH PF03938.9 KND93656.1 - 0.0034 17.3 0.7 1.2 9.0 0.0 2.2 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Prominin PF05478.6 KND93656.1 - 0.013 13.0 0.4 0.029 11.9 0.1 1.6 2 0 0 2 2 2 0 Prominin FliD_C PF07195.7 KND93656.1 - 0.041 13.1 0.2 0.053 12.8 0.2 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus THOC7 PF05615.8 KND93656.1 - 0.066 13.4 3.5 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Spc24 PF08286.6 KND93656.1 - 0.14 11.8 4.5 0.77 9.4 0.0 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Filament PF00038.16 KND93656.1 - 0.15 11.5 5.7 2.4 7.5 2.4 2.2 2 0 0 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 KND93656.1 - 0.32 10.8 1.7 2.5 7.9 0.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 KND93656.1 - 0.34 10.7 5.9 2.9 7.7 0.0 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CK2S PF15011.1 KND93656.1 - 0.6 9.8 4.2 2.3 7.9 0.9 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF1664 PF07889.7 KND93656.1 - 0.99 9.2 3.6 6.3 6.6 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 KND93656.1 - 1 6.9 6.8 1.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Myosin tail Calici_MSP PF05752.6 KND93656.1 - 1.4 8.4 4.2 31 4.1 2.1 2.2 2 0 0 2 2 2 0 Calicivirus minor structural protein CENP-F_leu_zip PF10473.4 KND93656.1 - 2.8 7.7 8.5 5.7 6.7 2.9 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1470 PF07336.6 KND93656.1 - 2.9 8.2 7.5 8 6.8 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1470) Cortex-I_coil PF09304.5 KND93656.1 - 7.8 6.5 8.7 4 7.5 0.4 2.9 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF4164 PF13747.1 KND93656.1 - 8.1 6.6 11.2 2.4 8.3 1.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Methyltransf_32 PF13679.1 KND93657.1 - 2.9e-19 69.1 0.0 7.1e-19 67.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND93657.1 - 0.037 14.6 0.0 0.081 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNB PF00773.14 KND93658.1 - 4.1e-74 249.7 0.0 8.5e-74 248.7 0.0 1.6 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 KND93658.1 - 0.28 10.5 0.2 0.63 9.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) GLE1 PF07817.8 KND93659.1 - 2.8e-19 69.0 0.0 7.7e-19 67.6 0.0 1.7 1 1 0 1 1 1 1 GLE1-like protein PAT1 PF09770.4 KND93659.1 - 0.99 7.5 22.4 1.3 7.2 15.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ferritin_2 PF13668.1 KND93660.1 - 2.1e-39 134.6 0.0 3.8e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Histidinol_dh PF00815.15 KND93660.1 - 0.15 10.6 0.9 0.21 10.2 0.6 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Gtr1_RagA PF04670.7 KND93662.1 - 1.3e-92 309.1 0.0 1.6e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KND93662.1 - 1.5e-07 30.9 0.0 2.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KND93662.1 - 1.8e-07 30.5 0.0 2.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND93662.1 - 1.7e-05 24.7 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND93662.1 - 0.0001 22.7 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KND93662.1 - 0.00079 18.8 0.8 0.0055 16.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KND93662.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter G-alpha PF00503.15 KND93662.1 - 0.01 14.5 0.1 0.27 9.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 KND93662.1 - 0.015 14.2 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SRPRB PF09439.5 KND93662.1 - 0.043 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KND93662.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KND93662.1 - 0.12 11.4 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Glyco_trans_2_3 PF13632.1 KND93663.1 - 2.4e-46 157.9 1.5 2.4e-46 157.9 1.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND93663.1 - 3.8e-09 36.6 0.0 7.1e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KND93663.1 - 0.0028 16.9 0.0 0.0075 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KND93663.1 - 0.0034 17.1 0.0 0.097 12.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DIOX_N PF14226.1 KND93665.1 - 6.2e-23 81.5 0.0 1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND93665.1 - 9e-16 57.9 0.0 1.6e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 KND93666.1 - 3e-61 206.5 0.0 4e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KND93666.1 - 4.3e-28 97.4 0.0 9.7e-28 96.3 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 KND93666.1 - 9.2e-06 25.8 0.0 2.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KND93666.1 - 0.00068 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region DUF4048 PF13257.1 KND93667.1 - 4.1e-08 33.1 24.1 4e-07 29.9 0.1 4.4 2 1 2 4 4 4 2 Domain of unknown function (DUF4048) DNA_ligase_A_M PF01068.16 KND93668.1 - 9.6e-22 77.3 0.0 1.8e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KND93668.1 - 5.6e-09 36.0 0.0 5e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 DNA ligase N terminus EF-hand_1 PF00036.27 KND93668.1 - 0.074 12.3 0.1 0.2 11.0 0.1 1.8 1 0 0 1 1 1 0 EF hand G8 PF10162.4 KND93669.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 G8 domain DUF4188 PF13826.1 KND93670.1 - 4.6e-29 100.8 0.4 6.2e-29 100.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 KND93670.1 - 0.0061 15.6 0.1 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase Glyco_hydro_76 PF03663.9 KND93672.1 - 6.1e-148 493.1 10.8 7.4e-148 492.8 7.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KND93672.1 - 0.00014 21.0 6.1 0.26 10.3 2.5 3.6 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 ECH_C PF13766.1 KND93673.1 - 8.8e-36 122.6 0.2 1.5e-35 121.9 0.2 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KND93673.1 - 1.2e-23 83.4 0.1 1.6e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Dak1 PF02733.12 KND93674.1 - 3.7e-109 364.2 8.5 6.3e-109 363.4 5.9 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KND93674.1 - 1.2e-44 152.0 1.3 1.9e-43 148.1 0.1 2.5 2 0 0 2 2 2 1 DAK2 domain Caps_synth PF05704.7 KND93675.1 - 1.3e-09 37.5 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KND93675.1 - 4e-05 23.9 0.0 6.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dynamin_N PF00350.18 KND93676.1 - 3.1e-29 101.9 0.0 8.1e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND93676.1 - 1.2e-15 57.0 0.0 2.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KND93676.1 - 1.8e-06 27.8 0.0 1.7e-05 24.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.13 KND93676.1 - 2.3e-06 27.4 0.2 1.9e-05 24.4 0.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.22 KND93676.1 - 0.022 15.0 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter FeoB_N PF02421.13 KND93676.1 - 0.033 13.4 0.0 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 KND93676.1 - 0.046 14.2 0.1 0.3 11.5 0.0 2.2 1 1 1 2 2 2 0 Miro-like protein AAA_28 PF13521.1 KND93676.1 - 0.1 12.5 1.5 3 7.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Ras PF00071.17 KND93676.1 - 0.11 11.8 0.1 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_21 PF13304.1 KND93676.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KND93676.1 - 0.2 11.9 1.9 0.21 11.9 0.1 2.1 2 1 0 2 2 1 0 AAA domain Ank_2 PF12796.2 KND93677.1 - 3.2e-15 56.2 0.0 3.2e-14 53.0 0.0 2.5 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND93677.1 - 1.9e-14 53.6 0.2 4.7e-09 36.5 0.0 3.2 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KND93677.1 - 8.2e-12 44.3 0.0 7.6e-05 22.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KND93677.1 - 3.8e-08 33.3 0.1 3.5e-07 30.2 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93677.1 - 3.1e-07 29.9 0.1 0.096 12.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.7 KND93677.1 - 3.2e-06 26.9 0.2 7.8e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 KND93677.1 - 0.0012 17.9 0.4 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.1 KND93677.1 - 0.0016 18.4 1.0 0.011 15.7 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND93677.1 - 0.0021 18.2 0.0 0.0073 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND93677.1 - 0.024 14.3 0.0 3.8 7.3 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_10 PF12846.2 KND93677.1 - 0.075 12.4 0.1 0.14 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 KND93677.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KND93677.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KND93677.1 - 0.21 11.7 0.0 0.63 10.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.20 KND93679.1 - 1.3e-21 76.8 0.0 5.4e-21 74.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93679.1 - 5.2e-10 38.8 0.0 0.00017 20.7 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KND93679.1 - 0.0086 15.8 0.0 0.031 14.0 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND93679.1 - 0.11 11.4 0.0 9.2 5.1 0.0 2.4 3 0 0 3 3 3 0 Kinase-like zf-CCHC_5 PF14787.1 KND93679.1 - 0.17 11.4 0.5 23 4.6 0.1 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger SpoVR PF04293.8 KND93680.1 - 0.01 14.2 0.5 0.012 13.9 0.3 1.1 1 0 0 1 1 1 0 SpoVR like protein Mid2 PF04478.7 KND93682.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 KND93682.1 - 0.042 12.1 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.1 KND93682.1 - 0.055 11.9 0.0 0.075 11.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless IncA PF04156.9 KND93682.1 - 0.46 10.0 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 IncA protein MFS_1 PF07690.11 KND93683.1 - 1.4e-18 66.7 55.7 6.4e-18 64.5 35.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND93683.1 - 8.3e-07 27.5 18.2 8.3e-07 27.5 12.6 1.9 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_72 PF03198.9 KND93684.1 - 1.3e-122 408.7 2.6 1.9e-122 408.1 1.8 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KND93684.1 - 3.2e-24 85.1 6.5 9.2e-24 83.7 4.5 1.8 1 0 0 1 1 1 1 X8 domain adh_short PF00106.20 KND93685.1 - 9.7e-08 32.1 0.0 2.5e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND93685.1 - 4.1e-06 26.7 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND93685.1 - 0.062 12.9 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 KR domain DUF904 PF06005.7 KND93685.1 - 0.095 13.0 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF1776 PF08643.5 KND93685.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PAD PF03068.10 KND93686.1 - 2.3e-47 161.2 0.0 3.7e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) HET PF06985.6 KND93687.1 - 1.1e-08 35.3 0.0 3.1e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 KND93688.1 - 2.7e-07 29.7 1.2 4.8e-07 28.9 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1966 PF09260.6 KND93688.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) FxsA PF04186.8 KND93689.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein zf-ribbon_3 PF13248.1 KND93689.1 - 0.24 10.6 20.5 0.41 9.9 0.8 4.5 4 0 0 4 4 4 0 zinc-ribbon domain Ank_2 PF12796.2 KND93690.1 - 3.2e-41 139.5 0.0 2.4e-21 75.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND93690.1 - 4.4e-33 111.4 0.0 4.7e-09 35.5 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KND93690.1 - 1.4e-24 83.7 0.0 1.3e-05 24.9 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KND93690.1 - 9.1e-24 83.3 0.0 2.5e-11 43.7 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND93690.1 - 6.7e-23 80.1 0.0 7e-09 35.6 0.0 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) AAA_22 PF13401.1 KND93690.1 - 0.00046 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND93690.1 - 0.0028 17.6 0.1 0.0098 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KND93690.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KND93690.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_S8 PF00082.17 KND93691.1 - 3.6e-06 26.3 0.0 1.1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Subtilase family Pmp3 PF01679.12 KND93692.1 - 6.5e-20 70.5 8.8 9e-20 70.1 6.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.6 KND93692.1 - 0.45 9.8 3.2 0.7 9.2 2.2 1.4 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE COX5B PF01215.14 KND93693.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb UCH PF00443.24 KND93694.1 - 2.4e-26 92.4 0.0 3.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KND93694.1 - 1.1e-12 47.9 0.1 1.1e-12 47.9 0.1 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KND93694.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KND93695.1 - 1.1e-67 221.6 32.5 1.6e-08 34.1 0.2 11.7 11 1 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 KND93695.1 - 5.9e-45 152.3 0.5 9e-45 151.7 0.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KND93695.1 - 4.9e-10 38.1 3.0 0.12 10.4 0.0 5.2 3 2 0 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KND93695.1 - 0.00051 18.8 2.5 3.1 6.4 0.0 4.7 4 1 0 5 5 5 2 Nup133 N terminal like SRP-alpha_N PF04086.8 KND93695.1 - 0.045 13.1 0.9 0.13 11.5 0.6 1.7 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MCM PF00493.18 KND93697.1 - 1.9e-141 470.6 0.2 2.9e-141 470.0 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KND93697.1 - 2.7e-19 69.8 1.0 6.2e-19 68.6 0.3 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND93697.1 - 2.3e-06 26.9 0.0 0.00019 20.6 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND93697.1 - 1.4e-05 24.8 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KND93697.1 - 0.00042 19.9 0.0 0.0022 17.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KND93697.1 - 0.02 15.2 0.7 0.085 13.2 0.5 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KND93697.1 - 0.038 13.4 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 KND93697.1 - 0.065 13.4 0.1 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 KND93698.1 - 3.9e-69 232.7 0.0 6.4e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93698.1 - 2.2e-35 122.0 0.0 5.3e-35 120.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93698.1 - 0.00025 20.1 0.0 0.00045 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND93698.1 - 0.0012 17.9 0.0 0.0027 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NADH_B2 PF14813.1 KND93699.1 - 0.027 14.1 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 phage_tail_N PF08400.5 KND93699.1 - 0.048 13.3 0.3 0.075 12.7 0.2 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Skp1 PF01466.14 KND93699.1 - 0.25 11.3 2.3 0.5 10.4 1.6 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Abhydrolase_6 PF12697.2 KND93700.1 - 1.4e-11 44.7 0.0 2.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND93700.1 - 3e-08 33.4 0.0 5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND93700.1 - 2.7e-05 23.9 0.0 0.00012 21.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family IF4E PF01652.13 KND93701.1 - 7.2e-50 168.7 0.1 1e-49 168.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1917 PF08939.5 KND93701.1 - 0.079 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) ketoacyl-synt PF00109.21 KND93702.1 - 1.1e-68 231.4 2.7 1.1e-68 231.4 1.9 2.8 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KND93702.1 - 4.7e-33 113.5 0.2 1.6e-20 73.0 0.0 2.9 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KND93702.1 - 2.8e-17 63.0 0.0 1.4e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Acyl_transf_1 PF00698.16 KND93702.1 - 9.2e-17 61.3 3.9 1.4e-16 60.7 0.5 2.7 2 1 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 KND93702.1 - 4.4e-15 55.6 1.0 1.3e-14 54.2 0.7 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 KND93702.1 - 1.9e-13 50.4 0.1 4.5e-09 36.1 0.0 3.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND93702.1 - 2e-11 43.8 0.2 2.4e-06 27.3 0.0 3.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 KND93702.1 - 6.5e-10 38.9 0.0 2.5e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.16 KND93702.1 - 1.7e-08 33.9 0.1 8.5e-06 25.1 0.0 3.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.1 KND93702.1 - 2e-08 33.9 0.0 4.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND93702.1 - 1.1e-07 32.0 0.0 7.2e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND93702.1 - 1.3e-07 32.0 0.0 2.1e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND93702.1 - 2.4e-06 28.1 0.0 9e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KND93702.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KND93702.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 KND93702.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 KND93702.1 - 0.75 8.7 0.0 1.5 7.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SGL PF08450.7 KND93703.1 - 2.6e-11 43.3 0.1 2.7e-10 40.0 0.1 2.2 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region NAD_binding_8 PF13450.1 KND93704.1 - 8e-11 41.8 0.2 1.6e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KND93704.1 - 8.8e-06 25.0 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KND93704.1 - 0.00015 20.8 0.6 0.009 14.9 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND93704.1 - 0.0002 19.9 0.1 0.00033 19.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KND93704.1 - 0.00041 20.4 0.0 0.001 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND93704.1 - 0.00059 20.1 0.1 0.0019 18.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KND93704.1 - 0.0032 16.6 0.0 0.006 15.7 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KND93704.1 - 0.0034 16.5 0.1 0.0053 15.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KND93704.1 - 0.0048 15.8 0.3 0.008 15.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KND93704.1 - 0.016 15.1 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GTP_EFTU PF00009.22 KND93705.1 - 0.084 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.13 KND93706.1 - 3.3e-09 36.4 8.7 3.3e-09 36.4 6.0 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KND93707.1 - 9.6e-19 67.9 0.0 5e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND93707.1 - 2.3e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND93707.1 - 6.1e-09 35.9 0.0 3.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KND93707.1 - 9.5e-05 22.4 0.0 0.00051 20.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND93709.1 - 1.1e-25 90.0 0.0 1.5e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KND93709.1 - 7.6e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KND93709.1 - 6e-07 29.5 1.8 1.3e-06 28.3 0.7 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND93709.1 - 2.3e-05 24.1 0.1 5.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND93709.1 - 0.017 14.0 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KND93709.1 - 0.018 15.0 0.1 0.061 13.3 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_12 PF08242.7 KND93709.1 - 0.041 14.3 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 KND93709.1 - 0.095 11.3 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KND93709.1 - 0.19 10.5 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain ketoacyl-synt PF00109.21 KND93710.1 - 1e-70 238.1 3.6 2.2e-70 237.0 2.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND93710.1 - 2.6e-33 115.7 0.0 1.4e-32 113.2 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KND93710.1 - 5e-31 107.0 0.0 1.1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KND93710.1 - 4.3e-11 42.9 0.2 1.3e-10 41.3 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KND93710.1 - 7.8e-07 28.3 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 KND93710.1 - 0.00045 20.6 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 KND93711.1 - 4.5e-18 65.4 4.5 2.6e-14 53.0 0.5 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KND93711.1 - 1.1e-05 25.3 0.3 0.00013 21.7 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KND93711.1 - 0.0071 15.2 7.2 0.023 13.6 2.8 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KND93711.1 - 0.1 11.4 1.2 0.45 9.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.5 KND93711.1 - 0.12 11.1 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 KND93711.1 - 0.25 11.4 4.4 0.31 11.0 0.5 2.8 2 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lysine_decarbox PF03641.9 KND93712.1 - 1.3e-31 109.1 0.1 1.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Lar_restr_allev PF14354.1 KND93713.1 - 0.15 12.3 1.2 6.6 7.1 0.1 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-Di19 PF05605.7 KND93713.1 - 0.15 12.1 0.9 26 5.0 0.0 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HET PF06985.6 KND93714.1 - 2.2e-30 105.6 0.0 7.7e-30 103.8 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Toxin_23 PF08093.6 KND93714.1 - 0.19 11.6 0.5 0.37 10.7 0.3 1.5 1 0 0 1 1 1 0 Magi 5 toxic peptide family ASXH PF13919.1 KND93715.1 - 7e-25 87.4 0.5 8e-25 87.2 0.4 1.0 1 0 0 1 1 1 1 Asx homology domain Elong_Iki1 PF10483.4 KND93716.1 - 2.1e-64 217.5 0.0 2.7e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 FTHFS PF01268.14 KND93716.1 - 0.044 11.7 0.0 0.076 10.9 0.0 1.3 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase COesterase PF00135.23 KND93717.1 - 5.4e-18 65.0 0.0 9e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Fic PF02661.13 KND93717.1 - 6.3e-15 55.6 0.0 1.2e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Abhydrolase_6 PF12697.2 KND93718.1 - 1.5e-28 100.2 0.7 1.8e-28 100.0 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND93718.1 - 2.9e-12 46.6 1.5 6.8e-12 45.4 1.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND93718.1 - 1e-09 38.3 0.0 2.2e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND93718.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 KND93718.1 - 0.078 12.9 0.7 0.12 12.2 0.5 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF3544 PF12064.3 KND93719.1 - 0.15 11.8 0.6 0.23 11.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) Fungal_trans PF04082.13 KND93720.1 - 5.9e-23 81.0 0.6 9.1e-23 80.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3948 PF13134.1 KND93720.1 - 0.079 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) adh_short_C2 PF13561.1 KND93722.1 - 2.6e-16 60.1 0.2 4.6e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND93722.1 - 1.3e-11 44.7 1.6 6.3e-06 26.2 0.0 2.5 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.5 KND93722.1 - 0.21 11.2 1.2 0.83 9.2 0.1 2.1 2 0 0 2 2 2 0 KR domain AMP-binding PF00501.23 KND93723.1 - 7.5e-81 271.6 0.0 5e-80 268.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND93723.1 - 7e-12 46.1 0.8 4.6e-11 43.5 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.9 KND93723.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2208 PF09973.4 KND93724.1 - 0.077 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) CTD PF12815.2 KND93725.1 - 4.6e-27 94.8 68.3 2e-20 73.4 29.0 4.7 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KND93725.1 - 6.4e-23 80.3 0.0 1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KND93725.1 - 8.9e-19 67.9 11.4 8.9e-19 67.9 7.9 4.1 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KND93725.1 - 3.6e-06 26.4 12.4 0.0037 16.9 0.7 5.1 6 0 0 6 6 6 2 KOW motif YajC PF02699.10 KND93725.1 - 7.7 6.2 9.4 2.3 7.9 0.5 3.7 3 1 1 4 4 4 0 Preprotein translocase subunit UCH PF00443.24 KND93726.1 - 1.8e-36 125.6 0.0 2.4e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND93726.1 - 9.3e-06 25.2 0.0 2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 KND93726.1 - 0.044 13.7 0.2 6.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) adh_short PF00106.20 KND93727.1 - 1.5e-17 64.0 3.1 5.4e-17 62.2 2.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND93727.1 - 2.7e-07 30.4 0.1 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND93727.1 - 1.5e-06 28.1 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Rox3 PF08633.5 KND93728.1 - 2.6e-49 168.1 0.0 4.3e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit Fungal_trans PF04082.13 KND93729.1 - 4.6e-28 97.8 0.1 9.1e-28 96.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93729.1 - 1e-10 41.3 11.3 1.8e-10 40.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 KND93729.1 - 0.042 12.3 0.0 0.085 11.3 0.0 1.5 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor DUF217 PF02697.9 KND93729.1 - 0.13 12.5 2.2 3.1 8.1 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized ACR, COG1753 UbiA PF01040.13 KND93730.1 - 5e-09 35.7 11.6 2.6e-06 26.8 8.0 2.8 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 KND93731.1 - 5.3e-26 91.1 0.0 7.1e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KND93733.1 - 4.2e-12 45.1 0.1 4.1e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme DUF1191 PF06697.7 KND93734.1 - 0.0038 16.0 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Alpha_GJ PF03229.8 KND93734.1 - 0.0091 16.3 6.1 0.0091 16.3 4.2 3.5 3 1 0 3 3 3 1 Alphavirus glycoprotein J DUF998 PF06197.8 KND93734.1 - 0.02 14.2 1.3 0.044 13.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Syndecan PF01034.15 KND93734.1 - 0.18 11.4 0.1 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF676 PF05057.9 KND93735.1 - 1e-06 28.1 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND93735.1 - 4.2e-06 26.5 0.0 1.3e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KND93735.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND93735.1 - 2.6e-05 24.1 0.7 7.3e-05 22.7 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KND93735.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KND93735.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) OmpH PF03938.9 KND93735.1 - 0.1 12.5 14.6 0.18 11.7 10.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Thioesterase PF00975.15 KND93735.1 - 0.22 11.7 5.0 0.22 11.6 0.0 2.5 2 0 0 2 2 2 0 Thioesterase domain UreF PF01730.11 KND93735.1 - 1.3 9.1 7.7 2.9 7.9 5.4 1.5 1 0 0 1 1 1 0 UreF COG2 PF06148.6 KND93736.1 - 1.1e-25 90.0 0.2 2e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 KND93736.1 - 4.5e-05 23.4 0.6 0.00011 22.1 0.2 1.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KND93736.1 - 0.00013 21.7 0.1 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Atg14 PF10186.4 KND93736.1 - 0.0067 15.4 0.5 0.0091 14.9 0.3 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KND93736.1 - 0.0087 14.7 1.3 0.022 13.4 0.9 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF2450 PF10475.4 KND93736.1 - 0.041 12.7 0.1 0.084 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF4611 PF15387.1 KND93736.1 - 0.068 13.3 2.3 0.17 12.0 1.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NPV_P10 PF05531.7 KND93736.1 - 0.068 13.4 3.6 0.31 11.2 0.1 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein F-box-like PF12937.2 KND93737.1 - 0.0029 17.2 0.1 0.0072 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND93737.1 - 0.0052 16.4 0.9 0.0097 15.5 0.2 1.8 2 0 0 2 2 2 1 F-box domain Proho_convert PF12177.3 KND93737.1 - 0.082 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Prohormone convertase enzyme DUF2065 PF09838.4 KND93737.1 - 0.11 12.2 5.5 0.61 9.8 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) PARP PF00644.15 KND93738.1 - 1.3e-58 197.8 0.0 2.4e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KND93738.1 - 6.8e-41 139.0 0.3 9.8e-41 138.5 0.2 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KND93738.1 - 1.4e-20 72.9 0.1 3.2e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KND93738.1 - 1.1e-13 51.1 0.0 2.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KND93738.1 - 1.9e-06 27.6 0.1 5.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain Fungal_trans PF04082.13 KND93739.1 - 5.1e-21 74.7 0.4 7.4e-21 74.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93739.1 - 1.5e-18 66.4 23.0 1.3e-09 37.8 4.0 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_B PF00136.16 KND93741.1 - 3.6e-140 467.8 2.6 5.2e-140 467.3 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KND93741.1 - 4.3e-81 272.2 0.1 9.1e-81 271.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KND93741.1 - 1e-22 79.8 4.9 1e-22 79.8 3.4 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KND93741.1 - 1.2e-05 25.1 0.1 5.8e-05 22.9 0.1 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KND93741.1 - 0.00063 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 KND93741.1 - 0.21 11.3 10.2 0.057 13.1 0.6 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rhomboid PF01694.17 KND93742.1 - 1e-34 119.6 8.9 1e-34 119.6 6.2 2.3 3 0 0 3 3 3 1 Rhomboid family Zn_clus PF00172.13 KND93743.1 - 2.1e-09 37.1 11.9 4.9e-09 35.9 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND93743.1 - 0.0036 15.9 0.7 0.014 13.9 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-rbx1 PF12678.2 KND93744.1 - 1.3e-09 37.9 0.2 3.6e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KND93744.1 - 4.7e-08 32.7 7.3 2.1e-07 30.6 5.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KND93744.1 - 7.6e-07 28.6 0.5 1.4e-06 27.8 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND93744.1 - 1.7e-06 27.6 0.7 3.6e-06 26.5 0.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KND93744.1 - 0.0001 21.8 4.3 0.00042 19.9 3.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND93744.1 - 0.00053 19.9 2.1 0.00053 19.9 1.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 KND93744.1 - 0.011 13.5 0.1 0.015 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 KND93744.1 - 0.013 15.3 1.3 0.024 14.4 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KND93744.1 - 0.051 13.3 3.3 0.13 11.9 1.3 2.4 1 1 0 1 1 1 0 RING-type zinc-finger HSBP1 PF06825.7 KND93745.1 - 5.7e-10 38.6 0.0 7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Pkinase PF00069.20 KND93746.1 - 1.1e-60 205.0 0.0 1.5e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93746.1 - 3e-27 95.3 0.0 1.4e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KND93746.1 - 0.093 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RAI1 PF08652.6 KND93748.1 - 1.3e-28 98.5 0.0 2.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease ResIII PF04851.10 KND93748.1 - 0.029 14.2 0.0 0.14 11.9 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KND93749.1 - 7.7e-08 31.4 0.0 0.0056 15.5 0.0 2.4 1 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 TBPIP PF07106.8 KND93749.1 - 2.3 7.7 18.8 1 8.9 5.4 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COX5A PF02284.11 KND93750.1 - 2.2e-39 133.7 0.4 3e-39 133.3 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 KND93750.1 - 0.096 11.0 0.1 0.75 8.0 0.0 1.8 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ELO PF01151.13 KND93751.1 - 1.2e-62 211.5 20.3 1.4e-62 211.2 14.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.2 KND93752.1 - 4.2e-06 26.3 0.2 8.3e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND93752.1 - 0.055 13.1 1.0 0.43 10.2 0.7 2.3 1 1 0 1 1 1 0 F-box domain Glycogen_syn PF05693.8 KND93754.1 - 0 1138.7 0.0 0 1138.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KND93754.1 - 4.3e-07 29.5 0.0 0.00064 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KND93754.1 - 2.1e-05 24.1 0.1 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KND93754.1 - 3.3e-05 24.0 0.0 6.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain WD40 PF00400.27 KND93755.1 - 1.4e-32 110.3 12.8 1.8e-05 24.4 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 KND93755.1 - 4.4e-14 52.2 0.4 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 NLE (NUC135) domain Nucleoporin_N PF08801.6 KND93755.1 - 0.014 14.2 1.5 0.05 12.3 0.1 2.3 1 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 KND93755.1 - 0.12 10.4 3.5 1 7.4 0.2 2.6 2 2 0 2 2 2 0 Nucleoporin Nup120/160 Cohesin_load PF10345.4 KND93756.1 - 2.3e-117 392.7 0.6 3.5e-117 392.1 0.5 1.1 1 0 0 1 1 1 1 Cohesin loading factor Transglut_core PF01841.14 KND93756.1 - 9e-12 45.2 0.3 2.8e-11 43.6 0.2 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KND93756.1 - 4.3e-08 32.5 0.3 9.6e-08 31.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND93756.1 - 0.00013 21.2 0.9 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KND93756.1 - 0.00016 21.2 0.2 0.00037 20.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain TPR_2 PF07719.12 KND93756.1 - 0.16 11.9 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KND93757.1 - 9.6e-70 234.6 0.0 1.6e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93757.1 - 5.5e-49 166.5 0.0 8.4e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93757.1 - 2.9e-06 26.4 0.0 1.2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND93757.1 - 0.077 12.0 0.2 0.36 9.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3275 PF11679.3 KND93757.1 - 7.8 6.0 7.3 1.2 8.7 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3275) MS_channel PF00924.13 KND93758.1 - 2.2e-20 72.8 0.5 3.8e-20 72.1 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KND93758.1 - 0.00052 19.1 1.7 0.0012 17.9 1.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KND93758.1 - 0.0024 17.9 0.1 0.0067 16.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KND93758.1 - 0.0097 15.7 0.3 0.026 14.3 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain DUF2648 PF10855.3 KND93758.1 - 0.45 9.9 1.9 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) Ribosomal_L1 PF00687.16 KND93760.1 - 7.9e-28 97.3 0.0 1.5e-27 96.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Hap4_Hap_bind PF10297.4 KND93761.1 - 2.9e-09 36.4 7.1 6.7e-09 35.2 4.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KND93761.1 - 6.5e-06 26.0 3.3 1.3e-05 25.0 2.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4200 PF13863.1 KND93761.1 - 0.0062 16.4 11.4 0.01 15.7 7.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) RBM39linker PF15519.1 KND93761.1 - 0.075 13.3 0.9 0.37 11.0 0.0 2.8 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein OEP PF02321.13 KND93761.1 - 4.1 6.9 6.2 6.7 6.2 4.3 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein DUF3425 PF11905.3 KND93764.1 - 1.7e-31 108.8 0.1 2.7e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KND93764.1 - 0.00026 20.8 2.6 0.00045 20.1 1.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Fungal_trans_2 PF11951.3 KND93765.1 - 1.2e-10 40.6 1.6 1.5e-09 37.0 1.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93765.1 - 1.7e-06 27.8 5.8 3.3e-06 26.8 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4206 PF13901.1 KND93765.1 - 0.11 12.0 2.5 0.21 11.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Abhydrolase_5 PF12695.2 KND93766.1 - 1.1e-15 57.6 0.2 1.7e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KND93766.1 - 2e-14 52.7 0.0 4.1e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KND93766.1 - 1.7e-13 50.9 1.3 3.2e-13 50.0 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KND93766.1 - 2.8e-06 26.4 0.0 1.2e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KND93766.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KND93766.1 - 0.0035 16.9 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KND93766.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.3 1 1 0 1 1 1 0 PGAP1-like protein DUF4350 PF14258.1 KND93766.1 - 0.04 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Chlorophyllase PF07224.6 KND93766.1 - 0.06 12.1 0.0 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_1 PF00561.15 KND93766.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cytochrom_B_N PF00033.14 KND93767.1 - 0.0019 17.6 0.4 0.0025 17.1 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB PA14_2 PF10528.4 KND93769.1 - 8.9e-09 35.3 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KND93769.1 - 1.7e-08 34.1 0.3 3.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 PA14 domain p450 PF00067.17 KND93770.1 - 5.8e-47 160.2 0.0 9.4e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KND93771.1 - 5.8e-10 38.3 0.5 6e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93771.1 - 8e-06 25.6 12.2 1.3e-05 24.9 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HCBP_related PF06594.6 KND93773.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain NPP1 PF05630.6 KND93775.1 - 5.2e-61 205.9 1.6 6e-61 205.7 1.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Ank_2 PF12796.2 KND93776.1 - 5.9e-19 68.1 0.0 3.5e-08 33.6 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND93776.1 - 6.3e-19 66.7 4.2 0.0002 20.9 0.0 5.8 5 2 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KND93776.1 - 2.2e-14 53.5 0.6 0.00084 19.7 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93776.1 - 6e-13 47.6 0.3 0.21 11.9 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KND93776.1 - 3.8e-12 46.0 1.8 0.0003 20.9 0.2 4.0 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KND93777.1 - 9.7e-21 72.4 0.0 6.2e-07 28.9 0.0 4.4 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KND93777.1 - 5.9e-19 68.1 1.6 5e-13 49.2 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND93777.1 - 1.7e-13 50.6 0.3 6.8e-06 26.4 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93777.1 - 1e-12 46.9 0.0 0.0019 18.2 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 KND93777.1 - 4.7e-12 45.7 0.6 8e-09 35.4 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 KND93777.1 - 0.083 12.7 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Peptidase_M54 PF07998.6 KND93778.1 - 1.8e-10 40.9 2.0 2.1e-10 40.6 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M54 Reprolysin_3 PF13582.1 KND93778.1 - 0.0076 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KND93778.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KND93778.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.1 KND93778.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 KND93778.1 - 0.034 13.7 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KND93778.1 - 0.041 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 KND93778.1 - 0.07 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 KND93778.1 - 0.13 11.1 0.4 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 Peptidase M66 Metallopep PF12044.3 KND93778.1 - 0.16 10.4 0.2 0.29 9.5 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family PUL PF08324.6 KND93779.1 - 1.5e-36 125.5 0.0 2.1e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KND93779.1 - 1.7e-33 115.5 0.0 2.5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KND93779.1 - 1.6e-13 50.1 0.0 3.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KND93779.1 - 0.0059 16.8 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KND93779.1 - 0.025 14.3 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 KND93779.1 - 0.042 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Aa_trans PF01490.13 KND93780.1 - 1.3e-83 280.7 30.6 1.6e-83 280.4 21.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Suc_Fer-like PF06999.7 KND93780.1 - 1.9e-28 100.0 0.0 3.4e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.19 KND93780.1 - 6e-09 35.9 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KND93780.1 - 0.00056 20.4 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KND93780.1 - 0.18 11.6 0.1 0.43 10.4 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain AA_permease PF00324.16 KND93781.1 - 2.3e-56 191.1 32.0 2.9e-56 190.7 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND93781.1 - 4.5e-21 74.8 37.8 7.5e-21 74.1 26.2 1.3 1 0 0 1 1 1 1 Amino acid permease DUF2406 PF10295.4 KND93781.1 - 0.048 14.1 0.4 0.14 12.6 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) PDE6_gamma PF04868.7 KND93781.1 - 0.6 9.9 3.1 3.6 7.5 0.2 3.0 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit DZR PF12773.2 KND93782.1 - 0.29 10.9 2.1 0.25 11.1 0.2 1.8 2 0 0 2 2 2 0 Double zinc ribbon cobW PF02492.14 KND93783.1 - 1.2e-37 129.1 0.0 4.8e-37 127.1 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KND93783.1 - 0.0019 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KND93783.1 - 0.0055 16.4 0.1 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KND93783.1 - 0.0093 15.5 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KND93783.1 - 0.013 15.6 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KND93783.1 - 0.022 14.2 0.3 0.51 9.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KND93783.1 - 0.027 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND93783.1 - 0.044 13.5 0.1 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 KND93783.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 KND93783.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KND93783.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain GDA1_CD39 PF01150.12 KND93784.1 - 7.2e-83 278.4 0.0 9.1e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.12 KND93785.1 - 3.5e-11 42.2 0.0 3.9e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Myb_DNA-bind_6 PF13921.1 KND93787.1 - 0.00018 21.5 0.1 0.00075 19.5 0.0 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain BAF1_ABF1 PF04684.8 KND93787.1 - 0.0035 16.2 11.8 0.0051 15.7 8.2 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor UbiA PF01040.13 KND93788.1 - 1.2e-30 106.6 19.0 1.2e-30 106.6 13.2 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family Pkinase PF00069.20 KND93789.1 - 7.5e-22 77.7 0.0 4e-21 75.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93789.1 - 2.4e-06 26.8 0.0 0.023 13.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 KND93789.1 - 0.0096 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Aldedh PF00171.17 KND93790.1 - 2.7e-185 616.1 0.9 3e-185 615.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.1 KND93791.1 - 2.4e-52 177.9 39.4 2.4e-52 177.9 27.3 1.6 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KND93791.1 - 2e-21 75.9 33.1 3.3e-21 75.1 22.9 1.3 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.8 KND93791.1 - 0.0012 18.1 1.9 0.0034 16.6 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1182) DUF3493 PF11998.3 KND93791.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3493) Cu_amine_oxid PF01179.15 KND93792.1 - 2.2e-166 553.7 0.0 2.6e-166 553.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KND93792.1 - 1.9e-15 56.7 0.0 4.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KND93792.1 - 2.9e-14 52.9 1.5 3.5e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain NACHT PF05729.7 KND93793.1 - 8.1e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 NACHT domain VirJ PF06057.6 KND93796.1 - 0.044 13.5 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) TPR_2 PF07719.12 KND93797.1 - 3.6e-31 104.5 27.6 0.00016 21.3 0.0 10.8 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 KND93797.1 - 1.8e-28 96.9 13.9 0.0001 21.7 0.5 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 KND93797.1 - 2.9e-27 94.1 27.5 2.6e-08 33.3 0.1 7.6 5 2 1 7 7 7 5 TPR repeat Apc3 PF12895.2 KND93797.1 - 7.6e-26 90.0 20.1 1.3e-21 76.4 0.2 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KND93797.1 - 3.1e-24 85.0 17.9 0.00015 22.0 0.2 8.7 5 3 3 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KND93797.1 - 6e-21 74.1 22.3 2.3e-06 27.4 0.1 8.6 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KND93797.1 - 1.5e-18 65.0 2.9 0.0054 16.4 0.0 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KND93797.1 - 3.3e-17 62.6 29.4 9.7e-09 35.6 0.9 8.1 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND93797.1 - 1.7e-16 59.2 29.5 0.0024 18.3 0.1 10.7 6 3 5 11 11 10 3 Tetratricopeptide repeat TPR_10 PF13374.1 KND93797.1 - 3.3e-10 39.5 16.2 0.025 14.5 0.3 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND93797.1 - 5.3e-10 38.3 18.1 2.8 7.9 0.0 9.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 KND93797.1 - 3.7e-09 36.4 10.0 1.4 9.5 0.1 8.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KND93797.1 - 1.1e-08 34.8 13.6 2.5e-05 24.0 0.3 6.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND93797.1 - 1.9e-06 27.6 1.4 34 4.9 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.4 KND93797.1 - 0.011 15.1 1.4 1.2 8.4 0.0 3.8 2 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 KND93797.1 - 0.025 14.9 16.7 4.2 8.0 0.0 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat MtrA PF04208.9 KND93797.1 - 0.21 11.0 0.0 7.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A TPR_21 PF09976.4 KND93797.1 - 1.3 8.9 14.3 3 7.7 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KND93797.1 - 2.7 8.1 9.0 5.2 7.2 0.1 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 KND93798.1 - 1.8e-22 80.0 0.0 2.7e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND93798.1 - 1.6e-21 77.1 0.0 2.1e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND93798.1 - 1.5e-09 37.7 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND93798.1 - 0.0039 16.1 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 KND93798.1 - 0.047 13.5 0.5 0.11 12.3 0.1 1.7 1 1 1 2 2 2 0 ThiF family HA2 PF04408.18 KND93799.1 - 1.2e-19 70.2 0.1 3.5e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND93799.1 - 8.1e-13 48.0 0.0 3.4e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KND93799.1 - 2.8e-11 43.2 0.0 5.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KND93799.1 - 1.4e-08 34.4 0.1 1.7e-07 30.8 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND93799.1 - 0.00015 21.9 0.0 0.00053 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KND93799.1 - 0.011 14.6 0.0 0.029 13.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 KND93799.1 - 0.011 14.9 0.0 0.032 13.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 KND93799.1 - 0.017 14.9 1.2 0.57 9.9 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KND93799.1 - 0.038 13.0 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KND93799.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain DHDPS PF00701.17 KND93800.1 - 1.1e-35 122.6 0.0 1.5e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family EcKinase PF02958.15 KND93801.1 - 1.2e-15 57.4 0.0 7.4e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.18 KND93801.1 - 6.7e-09 35.8 2.9 7.8e-09 35.6 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND93801.1 - 0.039 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_7 PF13499.1 KND93802.1 - 0.0063 16.6 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KND93802.1 - 0.013 15.3 0.0 16 5.6 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain EF-hand_9 PF14658.1 KND93802.1 - 0.021 14.7 0.0 1.1 9.1 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain POT1 PF02765.12 KND93803.1 - 3.2e-10 40.0 0.0 8.8e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 STAG PF08514.6 KND93804.1 - 3.2e-24 84.9 0.0 9.2e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 STAG domain HEAT PF02985.17 KND93804.1 - 0.00024 20.8 0.1 8.4 6.7 0.0 5.2 4 1 0 4 4 4 1 HEAT repeat DcpS_C PF11969.3 KND93805.1 - 1.1e-14 54.6 0.5 1.2e-07 31.9 0.1 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KND93805.1 - 7.4e-14 52.0 0.1 1.9e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 HIT domain T2SI PF02501.12 KND93805.1 - 0.088 12.7 0.1 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Arm PF00514.18 KND93806.1 - 5.8e-91 295.5 13.9 5.3e-13 48.2 0.1 8.7 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KND93806.1 - 3.5e-22 78.4 0.1 4.2e-09 36.5 0.0 5.6 1 1 2 4 4 4 3 HEAT repeats IBB PF01749.15 KND93806.1 - 2.6e-21 75.5 1.2 7e-21 74.2 0.8 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KND93806.1 - 3.2e-20 71.9 7.0 5.4e-09 36.2 0.1 6.1 4 1 2 6 6 6 3 HEAT-like repeat HA2 PF04408.18 KND93806.1 - 1.6e-18 66.5 1.1 5.1e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) HEAT PF02985.17 KND93806.1 - 7.3e-18 63.0 0.4 2.1e-05 24.2 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat OB_NTP_bind PF07717.11 KND93806.1 - 3.3e-15 55.9 0.0 7.6e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KND93806.1 - 2.1e-14 53.1 0.0 7.4e-14 51.3 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND93806.1 - 3.3e-09 36.4 0.1 8.2e-09 35.1 0.0 1.7 2 0 0 2 2 1 1 DEAD/DEAH box helicase RWD PF05773.17 KND93806.1 - 4.8e-08 32.8 1.1 9.6e-08 31.9 0.7 1.5 1 0 0 1 1 1 1 RWD domain Arm_2 PF04826.8 KND93806.1 - 9.9e-08 31.3 0.0 0.03 13.4 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 KND93806.1 - 0.00013 20.4 0.0 0.0023 16.3 0.0 2.4 1 1 2 3 3 3 1 Adaptin N terminal region AAA_25 PF13481.1 KND93806.1 - 0.00066 19.1 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND93806.1 - 0.0011 19.0 0.1 0.0031 17.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 KND93806.1 - 0.0024 18.1 0.5 0.0087 16.3 0.3 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 KND93806.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 KND93806.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HEAT_PBS PF03130.11 KND93806.1 - 0.021 15.2 0.1 5.8 7.6 0.0 4.2 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat KaiC PF06745.8 KND93806.1 - 0.022 13.8 0.8 0.033 13.2 0.0 1.6 2 0 0 2 2 1 0 KaiC ResIII PF04851.10 KND93806.1 - 0.032 14.0 0.0 0.14 12.0 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Proteasom_PSMB PF10508.4 KND93806.1 - 0.042 12.1 0.2 1.7 6.8 0.0 2.9 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 KND93806.1 - 0.06 13.2 0.2 8.5 6.3 0.0 4.0 3 1 0 4 4 3 0 V-ATPase subunit H AAA_23 PF13476.1 KND93806.1 - 0.075 13.3 0.0 0.075 13.3 0.0 2.1 3 0 0 3 3 1 0 AAA domain Kinesin PF00225.18 KND93807.1 - 2.2e-114 381.6 0.0 3.6e-114 380.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF2018 PF09442.5 KND93807.1 - 0.32 11.5 5.2 0.56 10.8 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF972 PF06156.8 KND93807.1 - 1.3 9.3 9.0 13 6.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Cwf_Cwc_15 PF04889.7 KND93808.1 - 0.46 10.1 2.9 0.61 9.7 2.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.5 KND93808.1 - 2.9 8.5 10.4 0.25 11.9 4.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) IF4E PF01652.13 KND93809.1 - 8.8e-35 119.6 0.1 1.1e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 KND93811.1 - 8.2e-46 156.2 0.0 5.4e-45 153.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93811.1 - 1e-31 109.9 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND93811.1 - 0.00026 20.1 0.0 0.002 17.2 0.0 2.4 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND93811.1 - 0.00033 19.6 0.0 0.00074 18.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KND93811.1 - 0.42 9.3 0.1 1.4 7.6 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase NUP PF06516.6 KND93812.1 - 7.5e-117 389.6 0.0 8.7e-117 389.4 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) MFS_1 PF07690.11 KND93813.1 - 6.4e-44 150.0 27.6 6.4e-44 150.0 19.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND93813.1 - 1.5e-07 30.3 6.3 1.5e-07 30.3 4.4 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KND93813.1 - 0.00039 18.7 0.4 0.00039 18.7 0.3 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 KND93813.1 - 0.0032 16.2 0.5 0.015 14.0 0.2 1.8 1 1 1 2 2 2 1 BT1 family OATP PF03137.15 KND93813.1 - 0.12 10.3 3.0 10 4.0 2.1 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PRA1 PF03208.14 KND93813.1 - 1 8.6 5.7 0.36 10.1 1.3 2.2 2 0 0 2 2 2 0 PRA1 family protein Zn_clus PF00172.13 KND93814.1 - 6.4e-06 25.9 4.0 1.1e-05 25.1 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1748 PF08520.5 KND93815.1 - 4.6e-28 96.6 0.2 5.9e-24 83.4 0.0 2.2 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF1748) PK PF00224.16 KND93816.1 - 1.6e-168 559.7 4.3 1.9e-168 559.4 3.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KND93816.1 - 3.8e-31 107.0 0.0 1.1e-30 105.5 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KND93816.1 - 3.8e-05 22.6 1.6 0.00028 19.8 0.4 2.2 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KND93816.1 - 0.013 14.4 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain WD40 PF00400.27 KND93817.1 - 1.8e-22 78.3 7.0 5.8e-09 35.5 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Se-cys_synth_N PF12390.3 KND93818.1 - 0.012 15.7 0.0 0.035 14.1 0.0 1.9 1 0 0 1 1 1 0 Selenocysteine synthase N terminal DUF4140 PF13600.1 KND93818.1 - 2.5 8.5 13.6 9.9 6.6 0.0 4.7 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 KND93818.1 - 9.5 5.1 6.1 3.3 6.6 0.5 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 E1-E2_ATPase PF00122.15 KND93819.1 - 1.3e-52 178.1 3.3 2.7e-52 177.1 2.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND93819.1 - 6.5e-43 146.3 5.7 6.5e-43 146.3 4.0 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND93819.1 - 3.3e-26 93.0 0.0 4.1e-25 89.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND93819.1 - 1.7e-18 66.3 0.0 3.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KND93819.1 - 3.5e-12 46.8 0.0 9.2e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND93819.1 - 5e-07 29.5 0.5 1e-05 25.2 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND93819.1 - 1.9e-06 27.2 0.6 5.8e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Dak1_2 PF13684.1 KND93819.1 - 0.0077 15.2 1.5 0.012 14.5 1.0 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family ABC_membrane PF00664.18 KND93820.1 - 6.8e-70 235.6 23.8 5.3e-38 130.9 0.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND93820.1 - 1.3e-58 197.1 0.0 3.3e-28 98.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND93820.1 - 6.7e-15 55.8 0.0 0.0005 20.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KND93820.1 - 1.6e-14 53.6 1.3 0.00016 21.0 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KND93820.1 - 4.9e-08 33.1 1.1 0.0065 16.4 0.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KND93820.1 - 8.3e-08 31.6 1.4 0.0078 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KND93820.1 - 1.7e-07 30.8 0.4 0.012 14.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KND93820.1 - 2.9e-07 29.8 0.1 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND93820.1 - 9.9e-07 28.9 0.5 0.23 11.5 0.0 3.9 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KND93820.1 - 5.6e-06 25.2 0.1 0.00061 18.4 0.0 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KND93820.1 - 7.9e-06 25.7 0.1 0.0095 15.8 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KND93820.1 - 8.9e-06 26.5 0.0 0.12 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KND93820.1 - 0.00023 20.6 5.5 1.5 8.1 0.2 4.1 4 0 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 KND93820.1 - 0.00055 19.8 1.1 0.45 10.2 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 KND93820.1 - 0.0012 19.1 1.6 0.13 12.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 KND93820.1 - 0.0043 16.7 0.1 2.9 7.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_5 PF07728.9 KND93820.1 - 0.0076 15.9 0.5 6.6 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KND93820.1 - 0.018 15.5 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 KND93820.1 - 0.019 14.8 1.5 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KND93820.1 - 0.051 13.7 0.2 9.5 6.4 0.1 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 KND93820.1 - 0.056 13.4 2.9 1.2 9.1 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 KND93820.1 - 0.058 13.5 0.0 85 3.3 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KND93820.1 - 0.062 12.7 2.3 5.3 6.4 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KND93820.1 - 0.078 13.2 0.5 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KND93820.1 - 0.082 12.6 2.9 5.4 6.7 0.2 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 KND93820.1 - 0.22 9.9 0.0 16 3.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.11 KND93820.1 - 2.1 7.3 2.5 6.2 5.8 0.0 2.5 3 0 0 3 3 3 0 AIG1 family KaiC PF06745.8 KND93820.1 - 5.4 6.0 5.8 19 4.2 0.1 3.2 4 0 0 4 4 4 0 KaiC tRNA-synt_1c PF00749.16 KND93821.1 - 7.7e-99 330.2 0.4 5e-98 327.6 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KND93821.1 - 3.9e-38 130.8 0.0 6.6e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KND93821.1 - 0.042 14.3 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2730 PF10805.3 KND93821.1 - 0.16 11.7 0.3 3.9 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) SurE PF01975.12 KND93822.1 - 2.2e-28 98.9 0.0 3.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.1 KND93822.1 - 0.011 15.8 2.1 0.022 14.8 1.5 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain GIY-YIG PF01541.19 KND93823.1 - 1.5e-09 38.0 0.0 3.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.1 KND93823.1 - 0.0043 17.0 1.7 0.0072 16.3 1.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain T5orf172 PF10544.4 KND93823.1 - 0.036 14.4 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain zf-HC5HC2H PF13771.1 KND93823.1 - 0.04 14.0 3.6 0.067 13.3 2.5 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KND93823.1 - 0.058 13.1 6.2 0.11 12.2 1.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KND93823.1 - 1.3 8.8 8.0 0.049 13.3 1.6 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 KND93823.1 - 4.7 7.2 5.7 2.2 8.3 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF3449 PF11931.3 KND93824.1 - 3.2e-23 82.2 1.3 8.3e-21 74.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KND93824.1 - 1.3e-09 37.3 0.1 2.8e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 KND93824.1 - 1.2e-06 28.4 0.1 2.3e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND93824.1 - 3e-06 27.2 0.2 6.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KND93824.1 - 0.023 14.7 0.1 0.085 12.9 0.1 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 KND93824.1 - 0.065 12.9 1.2 0.28 10.9 0.5 2.2 2 0 0 2 2 2 0 DBF zinc finger Spc97_Spc98 PF04130.8 KND93825.1 - 1.2e-62 212.0 0.7 2.8e-62 210.7 0.5 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KND93825.1 - 2.8e-12 45.5 0.1 4e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Abhydrolase_2 PF02230.11 KND93826.1 - 1e-09 38.1 0.0 2.1e-08 33.8 0.0 2.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KND93826.1 - 4e-07 29.8 0.1 5.7e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND93826.1 - 6e-07 29.5 1.0 9.3e-07 28.9 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND93826.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase LCCL PF03815.14 KND93827.1 - 1.3e-19 69.9 0.3 2.1e-19 69.2 0.2 1.3 1 0 0 1 1 1 1 LCCL domain TGT PF01702.13 KND93828.1 - 7.3e-38 130.1 0.0 9.8e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PQ-loop PF04193.9 KND93829.1 - 4.5e-18 64.5 2.5 3.6e-12 45.6 0.5 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1908 PF08926.6 KND93829.1 - 0.19 10.4 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Fungal_trans PF04082.13 KND93830.1 - 1.6e-14 53.3 0.0 2.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93830.1 - 7e-07 29.0 8.7 1.2e-06 28.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KND93831.1 - 2.2e-28 97.0 6.8 1.1e-08 34.6 0.4 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KND93831.1 - 0.072 13.3 17.8 0.14 12.4 0.1 5.9 6 1 1 7 7 7 0 PQQ-like domain MTHFR PF02219.12 KND93832.1 - 1.6e-98 329.3 0.0 2.2e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase eIF3_subunit PF08597.5 KND93833.1 - 0.29 10.6 4.2 0.66 9.4 2.9 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Metallophos PF00149.23 KND93834.1 - 3.3e-41 140.8 0.7 4.8e-41 140.3 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin PF00085.15 KND93835.1 - 2.3e-59 197.5 0.4 2.3e-30 104.3 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 KND93835.1 - 2.2e-23 82.6 0.3 9e-23 80.7 0.2 2.1 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KND93835.1 - 1.6e-19 70.1 0.1 3.6e-08 33.5 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KND93835.1 - 3.1e-13 49.5 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KND93835.1 - 4.3e-12 45.9 0.6 3.6e-06 26.9 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KND93835.1 - 2.7e-07 30.5 0.0 0.039 13.7 0.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.16 KND93835.1 - 3.7e-07 29.8 0.8 0.0057 16.3 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_4 PF13462.1 KND93835.1 - 2.7e-05 24.2 0.1 1.2 9.0 0.0 3.9 2 2 2 4 4 4 2 Thioredoxin Redoxin PF08534.5 KND93835.1 - 0.00022 20.7 2.6 0.048 13.2 0.1 2.5 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KND93835.1 - 0.00041 19.9 0.0 0.44 10.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 KND93835.1 - 0.00048 19.8 0.0 0.35 10.7 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin domain Glutaredoxin PF00462.19 KND93835.1 - 0.013 15.4 0.2 13 5.8 0.0 3.6 2 1 0 2 2 2 0 Glutaredoxin HyaE PF07449.6 KND93835.1 - 0.021 14.7 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Ribosomal_S14 PF00253.16 KND93836.1 - 4.4e-19 67.6 5.6 4.8e-19 67.4 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 KND93836.1 - 0.0039 16.9 1.6 0.0048 16.6 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-P11 PF03854.9 KND93836.1 - 0.28 10.7 1.9 0.42 10.1 1.3 1.3 1 0 0 1 1 1 0 P-11 zinc finger ZZ PF00569.12 KND93836.1 - 0.4 10.2 4.2 3.5 7.2 2.9 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type bZIP_2 PF07716.10 KND93837.1 - 0.084 12.7 12.9 0.47 10.3 4.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 KND93837.1 - 0.12 12.3 7.1 0.13 12.2 3.3 2.0 1 1 1 2 2 2 0 bZIP transcription factor TAFII28 PF04719.9 KND93838.1 - 2.2e-21 75.4 0.2 3.1e-20 71.7 0.2 2.2 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Diphthamide_syn PF01866.12 KND93840.1 - 4.8e-47 160.6 0.0 1.1e-46 159.4 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein PSDC PF12588.3 KND93841.1 - 1.3e-41 141.5 0.2 1.9e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KND93841.1 - 4.3e-30 104.5 0.0 6.2e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase SpoVAB PF13782.1 KND93841.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AB MutS_V PF00488.16 KND93842.1 - 2.1e-78 262.9 0.2 3.3e-78 262.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND93842.1 - 1.1e-50 172.2 0.1 1.9e-50 171.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KND93842.1 - 5.8e-34 116.5 0.2 1.2e-33 115.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KND93842.1 - 3.9e-15 56.1 0.0 1.6e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KND93842.1 - 5e-13 49.0 0.2 1.2e-12 47.7 0.2 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KND93842.1 - 0.006 16.9 2.9 0.035 14.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KND93842.1 - 0.026 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KND93842.1 - 0.11 12.4 1.7 0.13 12.1 0.1 1.9 3 0 0 3 3 3 0 AAA domain FAD_binding_3 PF01494.14 KND93843.1 - 2e-11 43.5 0.0 3e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DEAD PF00270.24 KND93844.1 - 2.4e-40 137.7 0.2 4.6e-40 136.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND93844.1 - 7.6e-28 96.1 0.1 1.6e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 KND93844.1 - 0.018 14.5 0.8 0.042 13.4 0.6 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KND93844.1 - 0.019 14.7 0.2 0.049 13.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KND93844.1 - 0.023 14.5 0.1 0.075 12.8 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KND93844.1 - 0.047 13.4 0.3 0.15 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KND93844.1 - 0.054 12.6 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.1 KND93844.1 - 0.083 13.0 0.7 0.41 10.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KND93844.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF1688 PF07958.6 KND93845.1 - 4e-171 569.1 0.0 4.6e-171 568.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) EPL1 PF10513.4 KND93846.1 - 1.6e-30 106.4 3.9 1.6e-30 106.4 2.7 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KND93847.1 - 2.8e-26 88.7 10.7 3.3e-07 29.1 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KND93847.1 - 2.2e-23 82.1 2.3 2.8e-12 46.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KND93847.1 - 1.4e-19 68.1 3.9 4.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KND93847.1 - 1.5e-18 65.1 12.1 2.2e-06 26.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KND93847.1 - 6.5e-15 54.4 12.7 2.9e-05 23.5 0.4 4.5 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KND93847.1 - 4.9e-07 29.7 0.0 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KND93847.1 - 5.8e-06 26.0 7.0 0.0017 18.0 0.2 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Peptidase_M22 PF00814.20 KND93848.1 - 4.5e-76 255.8 0.1 5.4e-76 255.6 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 KND93848.1 - 0.041 13.4 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein AMPKBI PF04739.10 KND93849.1 - 3.7e-30 103.7 1.6 7.5e-30 102.7 0.4 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain NIF PF03031.13 KND93850.1 - 8.5e-19 67.7 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.14 KND93851.1 - 4.3e-41 138.9 0.0 7.7e-41 138.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KND93851.1 - 1.9e-14 53.3 0.0 5.6e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND93851.1 - 1.2e-09 37.8 0.1 3.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND93851.1 - 2.8e-07 30.9 0.0 6.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KND93851.1 - 8.6e-06 25.9 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KND93851.1 - 1.7e-05 24.9 0.0 5.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KND93851.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Ribosomal_S9 PF00380.14 KND93853.1 - 2e-36 124.8 0.2 3.1e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Chorismate_bind PF00425.13 KND93854.1 - 7.8e-63 212.1 0.0 3.8e-58 196.8 0.0 2.5 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KND93854.1 - 3.8e-23 81.9 0.0 4.3e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KND93854.1 - 1.4e-14 54.2 0.0 3.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KND93854.1 - 2.9e-05 23.6 0.2 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 RabGAP-TBC PF00566.13 KND93855.1 - 6.2e-35 120.6 0.7 1.2e-34 119.6 0.5 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KND93855.1 - 7.8e-09 35.1 0.0 6.1e-05 22.4 0.0 3.9 3 1 0 4 4 4 2 Domain of unknown function (DUF3548) DUF1754 PF08555.5 KND93856.1 - 4.9e-15 55.9 9.8 8.9e-15 55.0 6.8 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Red1 PF07964.6 KND93856.1 - 0.24 9.4 3.7 0.29 9.2 2.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Adaptin_binding PF10199.4 KND93856.1 - 0.65 10.2 6.6 0.92 9.7 4.5 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PBP1_TM PF14812.1 KND93856.1 - 2 8.8 9.1 3.7 7.9 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom37_C PF11801.3 KND93856.1 - 3.2 7.5 7.9 8.3 6.2 5.5 1.7 1 1 0 1 1 1 0 Tom37 C-terminal domain LamB_YcsF PF03746.11 KND93857.1 - 9.4e-67 224.6 0.1 1.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Alpha_GJ PF03229.8 KND93858.1 - 0.0092 16.3 2.8 0.0092 16.3 1.9 2.9 3 0 0 3 3 3 1 Alphavirus glycoprotein J Herpes_gE PF02480.11 KND93858.1 - 0.017 13.3 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adaptin_N PF01602.15 KND93859.1 - 1.4e-62 211.7 0.0 2.8e-62 210.7 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region UQ_con PF00179.21 KND93861.1 - 1.2e-22 79.9 0.0 1.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KND93861.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain B-block_TFIIIC PF04182.7 KND93862.1 - 7e-14 51.4 0.0 1.8e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KND93862.1 - 0.0056 16.3 0.1 0.041 13.5 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 KND93862.1 - 0.0081 16.4 0.0 0.082 13.2 0.1 2.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain Ebp2 PF05890.7 KND93864.1 - 2.9e-92 308.8 12.1 2.9e-92 308.8 8.4 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 MOSP_N PF02707.11 KND93864.1 - 0.005 16.4 0.2 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Major Outer Sheath Protein N-terminal region zf-MYND PF01753.13 KND93865.1 - 6e-08 32.4 19.6 2e-07 30.7 13.6 1.9 1 0 0 1 1 1 1 MYND finger Cation_efflux PF01545.16 KND93867.1 - 2.3e-32 112.1 13.2 3e-32 111.8 9.1 1.1 1 0 0 1 1 1 1 Cation efflux family Dynamin_N PF00350.18 KND93868.1 - 1.6e-43 148.4 0.0 3.2e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND93868.1 - 1.7e-10 40.2 0.1 6.1e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KND93868.1 - 0.00083 19.2 0.0 0.0094 15.8 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KND93868.1 - 0.0023 18.4 0.1 0.009 16.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KND93868.1 - 0.03 14.3 0.2 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 KND93868.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain STAT_int PF02865.12 KND93868.1 - 0.26 11.2 1.9 2.2 8.2 0.1 2.8 2 0 0 2 2 2 0 STAT protein, protein interaction domain Spb1_C PF07780.7 KND93869.1 - 4.1e-76 255.2 23.0 4.1e-76 255.2 15.9 4.1 3 1 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 KND93869.1 - 9.2e-56 187.7 11.6 9.2e-56 187.7 8.1 4.3 5 0 0 5 5 5 2 Domain of unknown function (DUF3381) FtsJ PF01728.14 KND93869.1 - 8.8e-54 182.2 0.0 2.1e-53 181.0 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Voldacs PF03517.8 KND93870.1 - 1.1e-25 90.1 0.1 1.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling UQ_con PF00179.21 KND93871.1 - 6.9e-31 106.5 0.0 9.4e-31 106.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KND93871.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Nop14 PF04147.7 KND93871.1 - 3.4 5.4 8.1 4.2 5.1 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KND93871.1 - 7.6 5.7 8.1 12 5.0 5.6 1.2 1 0 0 1 1 1 0 SDA1 Spo12 PF05032.7 KND93872.1 - 2.3e-13 49.4 1.9 2.6e-13 49.3 0.3 1.8 2 0 0 2 2 2 1 Spo12 family Sec10 PF07393.6 KND93873.1 - 2.2e-155 518.6 0.0 2.8e-155 518.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KND93873.1 - 5.7e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND93873.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain MCM2_N PF12619.3 KND93873.1 - 0.79 9.6 4.2 1.7 8.6 2.9 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 AA_kinase PF00696.23 KND93874.1 - 1.8e-35 122.6 0.0 5.1e-35 121.1 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KND93874.1 - 2.6e-14 52.3 1.0 2.7e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KND93874.1 - 1.4e-12 46.9 2.1 6.7e-08 31.9 0.1 2.5 2 0 0 2 2 2 2 ACT domain RAMP4 PF06624.7 KND93875.1 - 0.093 12.2 0.5 0.13 11.7 0.4 1.4 1 1 0 1 1 1 0 Ribosome associated membrane protein RAMP4 SMAP PF15477.1 KND93876.1 - 1e-15 57.7 7.0 1e-15 57.7 4.9 5.5 3 2 1 4 4 4 1 Small acidic protein family Glyco_hydro_3 PF00933.16 KND93877.1 - 4.1e-87 291.9 0.0 6.1e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND93877.1 - 1.3e-38 132.8 0.2 2.8e-37 128.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND93877.1 - 7.1e-26 89.9 0.1 1.3e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Mid1 PF12929.2 KND93879.1 - 1.9e-123 412.3 9.0 2.2e-123 412.1 6.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KND93879.1 - 0.29 11.4 8.1 0.59 10.5 0.9 3.0 2 1 1 3 3 3 0 Fz domain adh_short PF00106.20 KND93880.1 - 1.8e-26 93.0 4.9 2.8e-26 92.4 3.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND93880.1 - 1.9e-10 40.9 0.1 2.5e-10 40.5 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND93880.1 - 9.3e-10 38.4 3.5 1.8e-09 37.5 2.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND93880.1 - 3.1e-06 26.8 0.1 6.4e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND93880.1 - 0.00033 20.7 2.2 0.0095 15.9 1.4 2.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KND93880.1 - 0.0034 16.3 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KND93880.1 - 0.011 15.3 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KND93880.1 - 0.018 15.4 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HEM4 PF02602.10 KND93880.1 - 0.019 14.2 0.1 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Eno-Rase_NADH_b PF12242.3 KND93880.1 - 0.051 13.3 0.8 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KND93880.1 - 0.071 12.7 0.4 2 7.9 0.0 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein YjeF_N PF03853.10 KND93880.1 - 0.092 12.3 0.8 0.24 10.9 0.0 2.0 2 1 0 2 2 2 0 YjeF-related protein N-terminus NmrA PF05368.8 KND93880.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RFX_DNA_binding PF02257.10 KND93881.1 - 3.2e-29 100.8 0.1 8.3e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 KND93882.1 - 6.4e-32 109.1 6.1 8.5e-32 108.7 4.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 KND93882.1 - 0.027 13.4 0.7 1.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAD_binding_4 PF01565.18 KND93883.1 - 4.3e-13 48.9 0.0 6.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF410 PF04190.8 KND93885.1 - 2.8e-47 161.4 0.0 3.2e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) UPF0220 PF05255.6 KND93887.1 - 1.2e-62 210.0 2.1 1.3e-62 209.8 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ABC_tran PF00005.22 KND93889.1 - 5.4e-45 153.0 0.0 6.6e-25 88.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND93889.1 - 1.7e-44 152.2 35.6 3.8e-26 92.1 12.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_16 PF13191.1 KND93889.1 - 1.1e-05 25.5 0.1 0.017 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KND93889.1 - 4.9e-05 23.2 1.2 0.2 11.5 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KND93889.1 - 8.2e-05 22.7 0.1 5 6.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 KND93889.1 - 0.00014 22.3 0.9 0.23 11.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KND93889.1 - 0.0003 20.2 0.9 0.6 9.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 KND93889.1 - 0.00061 18.6 1.1 0.37 9.5 0.0 2.4 2 0 0 2 2 2 2 ArgK protein SMC_N PF02463.14 KND93889.1 - 0.0013 18.0 1.6 4.4 6.4 0.0 3.4 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KND93889.1 - 0.0013 17.9 0.6 0.5 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KND93889.1 - 0.0017 17.8 1.6 0.26 10.6 0.1 2.6 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 KND93889.1 - 0.002 17.2 0.1 0.76 8.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KND93889.1 - 0.0031 17.6 0.6 3.9 7.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND93889.1 - 0.0055 16.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 KND93889.1 - 0.0063 15.1 0.4 0.55 8.7 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 KND93889.1 - 0.0078 17.0 4.0 0.77 10.5 0.5 3.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KND93889.1 - 0.017 14.7 2.0 2.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KND93889.1 - 0.077 12.4 1.5 5.6 6.3 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.7 KND93889.1 - 0.09 12.4 0.2 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KND93889.1 - 0.27 11.4 0.2 34 4.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP11 PF06644.6 KND93889.1 - 0.28 10.6 6.3 2.9 7.3 2.8 2.2 2 0 0 2 2 2 0 ATP11 protein Dynamin_N PF00350.18 KND93889.1 - 0.46 10.2 12.7 0.15 11.8 0.3 3.6 3 0 0 3 3 3 0 Dynamin family DUF1510 PF07423.6 KND93889.1 - 3.4 6.9 22.7 0.061 12.6 7.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF87 PF01935.12 KND93889.1 - 5.6 6.7 15.3 0.21 11.4 0.5 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 Cutinase PF01083.17 KND93890.1 - 6.7e-44 149.7 0.1 8.4e-44 149.4 0.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 KND93890.1 - 0.0003 20.4 0.1 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND93890.1 - 0.00066 19.4 0.3 0.00097 18.9 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND93890.1 - 0.002 18.0 0.6 0.0024 17.7 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 KND93890.1 - 0.0041 15.8 0.0 0.0056 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family DUF2974 PF11187.3 KND93890.1 - 0.0043 16.4 0.1 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KND93890.1 - 0.0044 16.6 0.1 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 KND93890.1 - 0.014 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 KND93890.1 - 0.026 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KND93890.1 - 0.061 12.9 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.6 KND93890.1 - 0.077 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 KND93890.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) 3-dmu-9_3-mt PF06983.8 KND93891.1 - 8.7e-48 161.4 0.0 1.2e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase EamA PF00892.15 KND93893.1 - 3.8e-09 36.6 33.1 9.8e-09 35.3 1.5 3.5 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KND93893.1 - 8.8e-08 31.4 11.7 8.8e-08 31.4 8.1 1.6 2 0 0 2 2 2 1 UAA transporter family DUF914 PF06027.7 KND93893.1 - 9.7e-06 24.6 7.3 9.7e-06 24.6 5.0 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KND93893.1 - 2.5e-05 23.9 27.7 0.0012 18.5 6.8 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KND93893.1 - 4.3e-05 23.6 2.8 4.3e-05 23.6 1.9 3.7 4 0 0 4 4 4 1 Multidrug resistance efflux transporter SBP_bac_3 PF00497.15 KND93894.1 - 0.0018 17.5 0.0 0.0055 15.9 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 KND93894.1 - 0.0051 16.4 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like Fungal_trans_2 PF11951.3 KND93895.1 - 2.1e-48 164.8 0.9 5.1e-47 160.2 0.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93895.1 - 3.6e-07 29.9 7.3 8.4e-07 28.7 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND93896.1 - 1.1e-46 158.8 0.1 1.6e-46 158.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KND93896.1 - 1.2e-08 34.7 7.6 0.0015 18.7 0.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND93896.1 - 4e-05 23.6 12.2 0.00068 19.7 1.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND93896.1 - 0.011 16.0 0.3 0.011 16.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain TPR_10 PF13374.1 KND93897.1 - 6.7e-35 118.0 1.3 1.4e-10 40.7 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KND93897.1 - 2.5e-26 91.3 1.3 2.4e-14 53.0 0.0 3.2 2 1 2 4 4 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 KND93897.1 - 8.9e-09 34.6 0.0 1.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 KND93897.1 - 1.2e-08 34.1 2.3 0.079 12.8 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND93897.1 - 1.5e-06 28.7 0.8 0.014 16.0 0.0 3.7 3 0 0 3 3 2 2 Tetratricopeptide repeat AAA_22 PF13401.1 KND93897.1 - 7.9e-06 26.0 0.0 3e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 KND93897.1 - 2.4e-05 24.3 1.1 0.0003 20.7 0.0 2.7 2 1 0 3 3 3 1 Alpha/beta hydrolase family TPR_11 PF13414.1 KND93897.1 - 0.00016 21.2 0.0 0.0065 16.0 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_4 PF07721.9 KND93897.1 - 0.0023 18.1 0.4 4.6 7.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND93897.1 - 0.0025 17.3 0.3 14 5.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PGAP1 PF07819.8 KND93897.1 - 0.0025 17.4 0.0 0.0069 16.0 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein TPR_17 PF13431.1 KND93897.1 - 0.0038 17.2 0.2 8.3 6.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND93897.1 - 0.007 16.1 3.5 15 5.8 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF676 PF05057.9 KND93897.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.1 KND93897.1 - 0.024 14.6 0.8 0.092 12.7 0.1 2.3 2 1 0 2 2 1 0 AAA ATPase domain TPR_19 PF14559.1 KND93897.1 - 0.029 14.6 0.3 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF900 PF05990.7 KND93897.1 - 0.045 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KND93897.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_8 PF13181.1 KND93897.1 - 0.085 12.6 0.0 9 6.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND93897.1 - 0.26 12.0 3.3 52 4.8 0.0 4.8 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF3506 PF12014.3 KND93898.1 - 2.3e-40 137.5 0.0 5.2e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KND93898.1 - 1.3e-07 31.2 0.5 2.4e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND93898.1 - 0.00014 21.4 0.2 0.00025 20.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.13 KND93899.1 - 1.1e-05 25.2 14.2 2.7e-05 23.9 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lyase_1 PF00206.15 KND93900.1 - 1e-12 47.9 0.3 2e-12 46.9 0.1 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KND93900.1 - 8.7e-11 41.6 0.0 2.6e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Cupin_2 PF07883.6 KND93901.1 - 6.6e-09 35.1 0.0 1.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KND93901.1 - 0.00015 21.2 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KND93901.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain FAA_hydrolase PF01557.13 KND93902.1 - 1.5e-32 112.8 0.0 2.7e-32 111.9 0.0 1.4 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KND93902.1 - 3.5e-18 65.5 0.0 1e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Pkinase PF00069.20 KND93903.1 - 1.8e-24 86.3 0.0 2.3e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93903.1 - 1.3e-17 63.7 0.0 2.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND93903.1 - 1.1e-06 27.7 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND93903.1 - 0.00036 20.3 0.2 0.0018 18.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KND93903.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND93903.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HET PF06985.6 KND93904.1 - 8.1e-13 48.7 0.4 8.1e-13 48.7 0.3 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_S15 PF02129.13 KND93905.1 - 4.2e-41 141.1 0.0 6.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KND93905.1 - 1.8e-29 103.2 0.0 2.7e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KND93905.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND93905.1 - 7.7e-07 28.9 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND93905.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family IN_DBD_C PF00552.16 KND93905.1 - 0.16 11.4 1.4 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Integrase DNA binding domain Fungal_trans PF04082.13 KND93906.1 - 8e-10 38.0 0.4 1.8e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93906.1 - 0.14 12.0 4.4 0.4 10.6 3.1 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AMNp_N PF10423.4 KND93907.1 - 0.04 13.5 0.1 1.6 8.2 0.0 2.2 1 1 1 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Ras PF00071.17 KND93908.1 - 1.7e-54 183.5 0.0 2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND93908.1 - 8.6e-17 61.7 0.0 2.3e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND93908.1 - 5.6e-12 45.2 0.0 7.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND93908.1 - 1.7e-07 31.1 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KND93908.1 - 7.4e-06 25.2 0.0 1.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND93908.1 - 1.6e-05 24.4 0.3 0.0013 18.2 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KND93908.1 - 0.00081 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND93908.1 - 0.0011 18.1 0.1 0.002 17.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KND93908.1 - 0.0021 17.5 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KND93908.1 - 0.0027 17.7 0.0 0.0068 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 KND93908.1 - 0.0029 16.8 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 KND93908.1 - 0.0037 17.0 0.0 0.008 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KND93908.1 - 0.0044 16.6 0.2 0.0085 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KND93908.1 - 0.0054 16.4 0.2 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 KND93908.1 - 0.0075 15.7 0.1 0.066 12.6 0.0 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KND93908.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Septin PF00735.13 KND93908.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Septin MobB PF03205.9 KND93908.1 - 0.02 14.5 0.1 0.044 13.4 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KND93908.1 - 0.022 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 KND93908.1 - 0.054 12.7 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 KND93908.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KND93908.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter N-SET PF11764.3 KND93909.1 - 2.3e-42 144.7 4.9 1.4e-41 142.1 0.0 3.0 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KND93909.1 - 1.1e-22 79.0 0.1 2.3e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KND93909.1 - 9.6e-22 78.0 0.1 9.6e-22 78.0 0.1 3.6 4 1 0 4 4 4 1 SET domain Hint_2 PF13403.1 KND93910.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Hint domain Tropomyosin_1 PF12718.2 KND93911.1 - 9e-45 152.0 34.3 3.4e-32 111.2 16.8 2.1 2 0 0 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 KND93911.1 - 1.7e-06 27.2 30.6 0.01 14.9 1.5 3.0 2 1 1 3 3 3 3 Tropomyosin Mod_r PF07200.8 KND93911.1 - 0.00024 21.0 24.5 0.011 15.6 10.7 2.1 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 KND93911.1 - 0.0015 17.7 28.7 0.0044 16.2 12.0 2.1 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding IncA PF04156.9 KND93911.1 - 0.0026 17.3 30.9 0.011 15.2 12.7 2.7 1 1 1 2 2 2 1 IncA protein TMF_TATA_bd PF12325.3 KND93911.1 - 0.003 17.2 25.5 0.1 12.2 11.8 2.4 2 1 0 2 2 2 2 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 KND93911.1 - 0.0031 17.6 17.2 0.041 14.0 3.1 3.2 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 KND93911.1 - 0.0051 15.9 32.7 0.098 11.6 14.0 2.1 1 1 1 2 2 2 2 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KND93911.1 - 0.0053 16.6 28.2 0.031 14.1 0.9 3.0 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NABP PF07990.7 KND93911.1 - 0.0067 15.7 2.3 0.0071 15.6 1.6 1.2 1 0 0 1 1 1 1 Nucleic acid binding protein NABP Syntaxin-6_N PF09177.6 KND93911.1 - 0.0068 16.7 14.0 0.45 10.9 5.5 2.6 2 1 0 2 2 2 2 Syntaxin 6, N-terminal TBPIP PF07106.8 KND93911.1 - 0.017 14.6 24.0 0.13 11.8 0.6 2.9 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 KND93911.1 - 0.017 14.9 26.6 0.038 13.8 11.0 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 KND93911.1 - 0.021 14.7 29.2 0.026 14.4 5.5 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 KND93911.1 - 0.022 14.7 23.6 0.47 10.4 1.1 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 KND93911.1 - 0.06 11.8 21.5 0.3 9.4 14.9 1.8 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 KND93911.1 - 0.062 13.2 28.4 2.3 8.2 2.2 4.9 2 2 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 KND93911.1 - 0.13 12.6 23.2 1.9 8.8 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 KND93911.1 - 0.16 11.7 16.7 1.7 8.4 0.2 3.1 1 1 2 3 3 3 0 Laminin Domain II NPV_P10 PF05531.7 KND93911.1 - 0.2 11.8 11.1 4 7.7 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 KND93911.1 - 0.21 12.0 21.3 0.44 11.0 2.7 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) HOOK PF05622.7 KND93911.1 - 0.24 9.1 24.7 0.34 8.6 1.4 2.3 1 1 2 3 3 3 0 HOOK protein BRE1 PF08647.6 KND93911.1 - 0.24 11.3 21.3 0.77 9.7 0.8 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Uds1 PF15456.1 KND93911.1 - 0.27 11.2 21.8 0.056 13.4 4.6 2.8 1 1 1 2 2 2 0 Up-regulated During Septation Striatin PF08232.7 KND93911.1 - 0.31 11.3 23.0 0.16 12.2 9.8 2.2 1 1 1 2 2 2 0 Striatin family Nup54 PF13874.1 KND93911.1 - 0.34 10.5 20.1 0.45 10.1 0.4 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Uso1_p115_C PF04871.8 KND93911.1 - 0.36 10.7 22.2 2 8.3 0.5 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC155 PF14662.1 KND93911.1 - 0.37 10.3 29.8 2.4 7.6 13.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF4200 PF13863.1 KND93911.1 - 0.39 10.6 30.8 0.17 11.8 1.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 KND93911.1 - 0.51 10.6 32.7 2.9 8.2 1.8 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) KLRAQ PF10205.4 KND93911.1 - 0.82 9.7 21.5 0.086 12.8 5.8 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.4 KND93911.1 - 0.84 8.5 21.0 0.27 10.1 11.1 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Surfac_D-trimer PF09006.6 KND93911.1 - 0.96 9.2 0.0 0.96 9.2 0.0 3.9 4 1 1 5 5 4 0 Lung surfactant protein D coiled-coil trimerisation ERM PF00769.14 KND93911.1 - 1 8.8 31.8 4.2 6.8 11.0 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Serine_rich PF08824.5 KND93911.1 - 1 9.0 7.8 0.76 9.4 3.8 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain CtIP_N PF10482.4 KND93911.1 - 1.1 9.1 20.5 4.1 7.2 8.9 2.7 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF2458 PF10454.4 KND93911.1 - 1.1 9.1 20.2 2.4 8.0 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Cep57_CLD_2 PF14197.1 KND93911.1 - 1.3 8.9 28.8 2.5 8.1 1.5 4.2 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF677 PF05055.7 KND93911.1 - 1.6 7.3 10.8 0.4 9.3 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF677) FlaC_arch PF05377.6 KND93911.1 - 1.6 8.6 17.4 2.7 7.9 3.8 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Fez1 PF06818.10 KND93911.1 - 1.6 8.6 20.9 2.8 7.9 14.5 1.3 1 0 0 1 1 1 0 Fez1 Fmp27_WPPW PF10359.4 KND93911.1 - 1.8 6.8 19.7 0.41 9.0 4.7 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4482 PF14818.1 KND93911.1 - 1.9 9.1 25.0 0.54 10.9 2.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) TMF_DNA_bd PF12329.3 KND93911.1 - 2.5 7.9 34.1 5.6 6.8 1.1 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Cortex-I_coil PF09304.5 KND93911.1 - 2.8 8.0 26.3 5.5 7.0 4.3 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF2730 PF10805.3 KND93911.1 - 2.9 7.6 11.0 0.89 9.3 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Syntaxin PF00804.20 KND93911.1 - 3.1 7.9 19.3 4.7 7.4 0.4 2.6 2 1 0 2 2 2 0 Syntaxin bZIP_2 PF07716.10 KND93911.1 - 3.3 7.6 33.3 1.7 8.5 3.0 5.1 3 2 2 5 5 5 0 Basic region leucine zipper DUF1664 PF07889.7 KND93911.1 - 3.5 7.4 13.0 2.1 8.1 2.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3287 PF11690.3 KND93911.1 - 3.6 7.7 10.5 0.96 9.5 0.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF3287) Prefoldin_2 PF01920.15 KND93911.1 - 4.7 7.0 33.3 4.3 7.1 10.5 3.7 1 1 2 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 KND93911.1 - 4.7 7.3 17.1 2 8.5 2.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MAD PF05557.8 KND93911.1 - 5.3 5.0 26.8 0.83 7.6 10.6 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein MRL1 PF13003.2 KND93911.1 - 5.8 6.7 6.3 0.54 10.0 1.0 1.8 2 1 0 2 2 1 0 Ribosomal protein L1 AAA_27 PF13514.1 KND93911.1 - 6.4 4.3 27.2 4.8 4.7 3.6 2.1 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KND93911.1 - 7.5 3.7 27.7 11 3.1 19.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Nop25 PF09805.4 KND93912.1 - 3.1e-35 121.2 11.7 3.1e-35 121.2 8.1 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Nop53 PF07767.6 KND93912.1 - 0.044 12.7 19.1 0.012 14.6 4.6 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Herpes_UL25 PF01499.11 KND93912.1 - 0.058 11.7 2.0 0.072 11.3 1.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Dickkopf_N PF04706.7 KND93913.1 - 0.017 15.3 2.1 0.04 14.0 1.5 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF4202 PF13875.1 KND93914.1 - 1.5e-65 220.3 0.0 1.7e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Sterol-sensing PF12349.3 KND93917.1 - 3.4e-35 120.7 10.3 6.6e-35 119.8 7.2 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KND93917.1 - 1.6e-11 42.8 2.4 2.3e-11 42.4 1.7 1.1 1 0 0 1 1 1 1 Patched family 14-3-3 PF00244.15 KND93918.1 - 5.7e-08 32.1 0.1 9.2e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF543 PF04418.7 KND93919.1 - 0.13 12.2 0.8 0.34 10.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) 2-Hacid_dh_C PF02826.14 KND93920.1 - 3.2e-52 176.2 0.0 7.2e-52 175.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND93920.1 - 4.7e-14 51.9 0.0 7.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KND93920.1 - 4.4e-05 23.3 0.0 8.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KND93920.1 - 0.093 13.2 0.0 0.55 10.7 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AA_permease_2 PF13520.1 KND93921.1 - 1.4e-64 218.2 38.8 1.8e-64 217.9 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND93921.1 - 1.5e-28 99.3 26.9 1.5e-28 99.3 18.6 2.3 2 1 0 2 2 2 1 Amino acid permease DUF4405 PF14358.1 KND93921.1 - 0.035 14.2 2.8 0.21 11.7 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DUF4097 PF13349.1 KND93921.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) EXS PF03124.9 KND93922.1 - 7.3e-95 317.9 33.6 9.3e-95 317.5 23.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KND93922.1 - 1.8e-51 175.5 1.2 3.1e-51 174.7 0.0 1.9 2 0 0 2 2 2 1 SPX domain DDHD PF02862.12 KND93922.1 - 0.071 12.8 1.1 0.17 11.6 0.8 1.6 1 0 0 1 1 1 0 DDHD domain EF-1_beta_acid PF10587.4 KND93922.1 - 3.2 7.9 7.8 8 6.7 5.4 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region CTP_transf_1 PF01148.15 KND93923.1 - 1.3e-05 25.0 8.3 1.3e-05 25.0 5.7 3.5 3 2 0 3 3 3 1 Cytidylyltransferase family CcmH PF03918.9 KND93923.1 - 0.24 10.4 0.5 0.64 8.9 0.3 1.7 1 0 0 1 1 1 0 Cytochrome C biogenesis protein ORC2 PF04084.9 KND93924.1 - 4.3e-89 298.5 0.0 7e-89 297.8 0.0 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 KND93924.1 - 0.097 12.4 7.8 0.057 13.1 3.0 2.6 2 0 0 2 2 2 0 AT hook motif DUF1966 PF09260.6 KND93924.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) RNA_pol_Rpb1_5 PF04998.12 KND93925.1 - 1.1e-88 297.1 0.0 2.1e-88 296.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KND93925.1 - 2.6e-63 212.9 0.6 5.7e-63 211.7 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KND93925.1 - 3.7e-36 125.0 0.3 1.4e-32 113.3 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 KND93925.1 - 3.9e-31 107.9 0.0 1.3e-30 106.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KND93925.1 - 8.2e-17 60.9 0.0 2.5e-16 59.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Fungal_trans PF04082.13 KND93926.1 - 3e-38 131.2 2.3 6.8e-38 130.0 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND93926.1 - 1.2e-06 28.2 9.8 2.3e-06 27.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 KND93926.1 - 0.2 10.8 19.9 0.44 9.7 2.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Malic_M PF03949.10 KND93927.1 - 3.9e-82 275.6 0.0 6e-82 275.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KND93927.1 - 7.4e-72 240.7 0.0 1.2e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_16 PF00722.16 KND93928.1 - 4.4e-19 68.4 0.8 8.1e-12 44.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 DUF2957 PF11170.3 KND93928.1 - 0.039 12.5 0.1 0.077 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) DUF1049 PF06305.6 KND93928.1 - 0.5 9.8 1.7 1.1 8.7 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) GAS2 PF02187.12 KND93929.1 - 5.2e-05 22.9 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Ribosomal_L4 PF00573.17 KND93930.1 - 6.8e-40 136.5 0.0 9.4e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KND93930.1 - 5.1e-27 93.5 1.2 5.1e-27 93.5 0.8 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain FMO-like PF00743.14 KND93933.1 - 2e-32 112.1 0.1 2e-17 62.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND93933.1 - 1.6e-18 67.5 0.0 3.9e-18 66.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND93933.1 - 2.8e-11 43.6 0.0 4.7e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND93933.1 - 2.3e-10 40.4 2.3 1.2e-08 34.8 0.0 3.5 3 2 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KND93933.1 - 2.8e-09 36.8 0.0 5.6e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND93933.1 - 3.2e-09 36.1 0.0 0.004 16.0 0.0 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KND93933.1 - 5.9e-09 35.3 0.0 1.1e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KND93933.1 - 7.8e-08 31.6 0.2 8.8e-05 21.6 0.0 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KND93933.1 - 4.3e-06 25.4 0.1 0.015 13.7 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 KND93933.1 - 8.7e-05 21.7 0.1 0.00069 18.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KND93933.1 - 0.00014 20.8 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 KND93933.1 - 0.00021 21.6 0.2 0.052 13.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND93933.1 - 0.001 17.9 0.1 0.015 14.1 0.0 2.5 2 1 1 3 3 3 1 FAD binding domain Amino_oxidase PF01593.19 KND93933.1 - 0.0014 17.7 0.0 0.0056 15.8 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NMD3 PF04981.8 KND93933.1 - 0.0072 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 NMD3 family Shikimate_DH PF01488.15 KND93933.1 - 0.014 15.4 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KND93933.1 - 0.022 13.8 0.1 0.055 12.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.7 KND93933.1 - 0.028 13.8 0.1 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KND93933.1 - 0.04 13.6 0.1 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KND93933.1 - 0.05 12.7 0.1 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 KND93933.1 - 0.13 12.3 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 KND93933.1 - 0.14 12.2 0.1 0.73 9.8 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain MMR_HSR1 PF01926.18 KND93934.1 - 8.7e-17 61.1 0.2 3e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND93934.1 - 1.3e-07 31.0 0.2 2e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KND93934.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KND93934.1 - 0.0013 18.6 0.2 0.036 13.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 KND93934.1 - 0.021 13.9 0.1 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 KND93934.1 - 0.021 15.2 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF3320 PF11784.3 KND93935.1 - 4.4e-05 22.9 0.3 0.0011 18.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3320) HAD PF12710.2 KND93936.1 - 6.5e-08 32.9 0.0 9.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND93936.1 - 0.0025 18.0 0.0 0.0051 17.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TPR_10 PF13374.1 KND93937.1 - 9.8e-56 184.2 15.2 9.3e-10 38.1 0.0 6.8 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KND93937.1 - 1.9e-52 175.0 18.6 4.7e-16 58.4 0.6 5.1 2 1 2 5 5 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 KND93937.1 - 3.3e-27 92.9 26.9 0.0002 20.8 0.2 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 KND93937.1 - 1.7e-22 77.3 15.9 0.004 16.8 0.0 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 KND93937.1 - 8.4e-19 66.9 15.1 1.2e-07 31.2 0.7 4.4 1 1 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 KND93937.1 - 1.8e-18 64.8 17.9 0.019 14.8 0.2 6.9 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KND93937.1 - 2.4e-12 46.0 7.3 1.9 8.8 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KND93937.1 - 2.6e-12 45.6 18.1 0.21 11.4 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KND93937.1 - 5.6e-11 42.8 11.4 5.8e-05 23.6 0.3 4.9 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KND93937.1 - 2.1e-08 33.7 0.0 5 7.8 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND93937.1 - 9.8e-08 31.9 12.1 0.6 10.8 0.1 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF676 PF05057.9 KND93937.1 - 4.4e-06 26.1 0.0 8.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NB-ARC PF00931.17 KND93937.1 - 5.9e-05 22.0 0.0 0.0012 17.8 0.0 2.3 1 1 1 2 2 2 1 NB-ARC domain TPR_19 PF14559.1 KND93937.1 - 0.00066 19.9 10.3 0.95 9.8 0.1 4.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 KND93937.1 - 0.0008 19.1 1.8 1.5 8.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PGAP1 PF07819.8 KND93937.1 - 0.0012 18.4 0.5 0.0026 17.3 0.4 1.5 1 0 0 1 1 1 1 PGAP1-like protein PPR PF01535.15 KND93937.1 - 0.003 17.4 5.1 45 4.3 0.0 5.5 5 0 0 5 5 5 0 PPR repeat Abhydrolase_6 PF12697.2 KND93937.1 - 0.0061 16.4 2.7 0.011 15.6 0.1 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Apc3 PF12895.2 KND93937.1 - 0.024 14.7 1.2 2.6 8.2 0.0 3.6 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 YjeF_N PF03853.10 KND93937.1 - 0.058 12.9 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 YjeF-related protein N-terminus Arch_ATPase PF01637.13 KND93937.1 - 0.085 12.5 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 Archaeal ATPase TPR_6 PF13174.1 KND93937.1 - 5.3 7.7 19.4 22 5.7 0.2 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4075 PF13294.1 KND93937.1 - 6.7 6.8 6.9 64 3.6 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4075) Methyltransf_11 PF08241.7 KND93938.1 - 3.9e-10 40.0 0.0 1.8e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND93938.1 - 3.8e-07 30.3 0.0 6.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND93938.1 - 1.6e-06 28.1 0.4 2.6e-06 27.4 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND93938.1 - 3.1e-05 23.7 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND93938.1 - 9.7e-05 21.9 0.0 0.00034 20.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND93938.1 - 0.00035 19.7 0.0 0.00049 19.2 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KND93938.1 - 0.00078 20.0 0.0 0.0014 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND93938.1 - 0.01 16.3 0.0 0.021 15.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KND93938.1 - 0.028 13.8 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 KND93938.1 - 0.12 11.4 0.0 0.87 8.5 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase DUF2372 PF10178.4 KND93939.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Mito_carr PF00153.22 KND93940.1 - 1.1e-12 47.5 5.1 0.0039 16.8 0.0 5.1 4 1 0 4 4 4 4 Mitochondrial carrier protein COMPASS-Shg1 PF05205.7 KND93941.1 - 4.9e-23 81.4 0.5 4.9e-23 81.4 0.4 2.2 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1777 PF08648.7 KND93941.1 - 0.00023 20.9 36.7 0.00023 20.9 25.4 6.3 2 2 2 5 5 5 1 Protein of unknown function (DUF1777) TPT PF03151.11 KND93942.1 - 1.4e-25 89.6 12.1 1.4e-25 89.6 8.4 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KND93942.1 - 0.00045 19.2 15.1 0.032 13.1 2.0 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KND93942.1 - 0.021 14.8 31.8 0.068 13.2 7.7 2.7 3 0 0 3 3 3 0 EamA-like transporter family TauD PF02668.11 KND93943.1 - 1.6e-41 142.7 0.0 2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KND93943.1 - 0.00014 22.1 0.1 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) adh_short PF00106.20 KND93944.1 - 1.4e-16 60.8 1.7 3.4e-16 59.6 1.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND93944.1 - 2.4e-08 34.0 0.1 3e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND93944.1 - 0.00012 21.8 0.6 0.00022 20.9 0.4 1.5 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KND93944.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KND93944.1 - 0.064 13.0 0.6 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KND93944.1 - 0.083 12.5 0.8 0.18 11.4 0.5 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KND93945.1 - 2.1e-09 37.5 0.0 2.3e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CENP-S PF15630.1 KND93946.1 - 2.8e-34 117.1 0.0 3.9e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID-18kDa PF02269.11 KND93946.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-T PF15511.1 KND93946.1 - 0.055 12.7 0.1 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T WSC PF01822.14 KND93947.1 - 2.4e-54 181.1 49.8 1.7e-18 66.3 7.1 3.7 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.18 KND93947.1 - 4e-23 82.1 0.0 8.6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Peroxidase RCR PF12273.3 KND93948.1 - 0.0023 18.4 0.1 0.0066 16.9 0.1 1.8 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red MARVEL PF01284.18 KND93948.1 - 0.013 15.2 21.4 0.029 14.2 15.0 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF3938 PF13074.1 KND93948.1 - 0.29 10.9 2.4 0.7 9.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Sarcoglycan_1 PF04790.8 KND93948.1 - 0.35 10.0 1.2 0.51 9.4 0.8 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Adeno_E3B PF03376.9 KND93948.1 - 3 7.8 7.9 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein DUF3402 PF11882.3 KND93949.1 - 1e-144 482.6 0.0 1.4e-144 482.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KND93949.1 - 2.4e-72 243.2 0.0 3.7e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein SDA1 PF05285.7 KND93949.1 - 0.069 12.4 8.2 0.15 11.3 5.7 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KND93949.1 - 0.084 10.8 3.6 0.13 10.2 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2011 PF09428.5 KND93950.1 - 5.2e-22 78.1 13.1 8.9e-22 77.3 9.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.7 KND93952.1 - 1.2e-32 113.4 0.0 2.1e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family IBR PF01485.16 KND93953.1 - 5.7e-21 74.1 33.2 7.1e-14 51.4 1.7 4.0 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 KND93953.1 - 2.4e-16 59.6 0.0 4.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KND93953.1 - 3.1e-05 23.7 7.6 3.1e-05 23.7 5.3 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 KND93953.1 - 0.0052 16.7 8.9 0.0052 16.7 6.2 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND93953.1 - 0.011 15.4 8.5 0.011 15.4 5.9 4.1 3 1 1 4 4 4 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KND93953.1 - 0.013 15.1 8.9 0.013 15.1 6.2 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KND93953.1 - 4.3 7.3 26.7 3.3 7.6 0.5 3.4 3 0 0 3 3 3 0 FYVE zinc finger PALP PF00291.20 KND93955.1 - 2.4e-61 207.6 0.0 2.8e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.16 KND93956.1 - 4.6e-84 281.8 3.5 5.8e-84 281.4 2.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KND93956.1 - 7.2e-50 167.9 0.0 1.9e-49 166.5 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KND93956.1 - 0.0094 16.1 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding CoA_transf_3 PF02515.12 KND93957.1 - 1e-52 178.2 0.6 1.7e-52 177.4 0.4 1.4 1 0 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.15 KND93958.1 - 2.4e-104 348.2 0.8 6.6e-104 346.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KND93958.1 - 1e-55 188.1 0.0 2.1e-55 187.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KND93958.1 - 1.2e-28 98.8 5.8 2.6e-28 97.7 4.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KND93958.1 - 6.7e-05 22.8 0.7 0.0008 19.3 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KND93958.1 - 0.0074 16.7 0.0 0.042 14.3 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 KND93960.1 - 2.2e-10 39.9 10.8 1.3e-07 31.2 0.0 4.6 6 1 0 6 6 6 2 WD domain, G-beta repeat CLTH PF10607.4 KND93960.1 - 0.0018 17.9 0.2 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain CAS_CSE1 PF03378.10 KND93962.1 - 1.3e-149 498.2 0.0 1.9e-148 494.3 0.0 2.3 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KND93962.1 - 7.3e-147 488.7 1.4 1e-146 488.2 1.0 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KND93962.1 - 1e-11 44.5 0.0 2.9e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3384 PF11864.3 KND93963.1 - 1.4e-97 327.0 0.0 2.3e-97 326.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KND93963.1 - 1.8e-56 190.5 0.0 2.9e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KND93963.1 - 1.1e-26 93.8 0.3 1.7e-23 83.2 0.0 3.2 3 0 0 3 3 3 2 Tuberin ABC_tran PF00005.22 KND93964.1 - 2.9e-14 53.5 0.0 1.9e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND93964.1 - 4.7e-10 39.9 0.2 0.00058 19.9 0.3 2.1 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND93964.1 - 0.00035 20.0 0.0 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 KND93964.1 - 0.00042 17.8 0.2 0.00055 17.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 KND93964.1 - 0.001 18.1 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 KND93964.1 - 0.0026 17.2 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KND93964.1 - 0.0028 17.0 0.1 0.0048 16.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KND93964.1 - 0.0033 16.9 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family SMC_N PF02463.14 KND93964.1 - 0.0036 16.5 0.0 2.4 7.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND93964.1 - 0.004 17.5 0.0 0.0062 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND93964.1 - 0.0074 16.1 0.0 0.068 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KND93964.1 - 0.0081 16.3 0.0 0.052 13.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND93964.1 - 0.0091 16.8 0.5 0.027 15.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KND93964.1 - 0.013 15.5 0.2 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KND93964.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KND93964.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KND93964.1 - 0.025 14.5 0.9 0.1 12.5 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KND93964.1 - 0.033 14.3 0.2 0.091 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KND93964.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KND93964.1 - 0.085 12.5 0.2 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arf PF00025.16 KND93964.1 - 0.087 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.18 KND93964.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_13 PF13166.1 KND93964.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND93964.1 - 0.1 12.4 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KND93964.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KND93964.1 - 0.2 11.0 0.2 0.29 10.5 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CENP-I PF07778.6 KND93965.1 - 1.5e-105 353.3 0.0 2.1e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Mis6 DNA_pol_E_B PF04042.11 KND93966.1 - 5e-51 172.9 0.0 6.5e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.20 KND93967.1 - 7.9e-72 241.5 2.1 3.5e-36 124.6 0.0 4.4 4 1 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 KND93967.1 - 2.6e-70 236.6 2.8 2.6e-70 236.6 1.9 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 KND93967.1 - 4e-46 157.1 0.0 6.2e-21 74.6 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 KND93967.1 - 3.2e-15 56.0 1.3 4.3e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 KND93967.1 - 8.7e-13 48.1 0.1 2.4e-12 46.7 0.1 1.8 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KND93967.1 - 0.00045 20.0 4.4 0.047 13.4 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KND93967.1 - 0.18 10.5 0.1 7.2 5.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Spt5_N PF11942.3 KND93967.1 - 0.82 10.3 24.3 0.17 12.5 5.2 3.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Cut12 PF11500.3 KND93968.1 - 2.6e-38 131.0 11.4 2.6e-38 131.0 7.9 3.3 1 1 1 3 3 3 1 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.7 KND93968.1 - 0.78 9.6 14.9 2.1 8.3 0.2 5.1 4 1 1 5 5 5 0 Viral A-type inclusion protein repeat TGS PF02824.16 KND93969.1 - 6.5e-19 67.5 0.1 1.4e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 KND93969.1 - 1.4e-18 66.9 0.0 3.3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND93969.1 - 9.1e-13 47.7 0.0 1.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KND93969.1 - 8.4e-05 22.4 0.5 0.032 14.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KND93969.1 - 0.0041 17.6 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KND93969.1 - 0.067 11.9 0.1 0.14 10.8 0.1 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KND93969.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family RRM_1 PF00076.17 KND93970.1 - 9.3e-07 28.3 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND93970.1 - 3.9e-05 23.4 0.0 9.8e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND93970.1 - 0.00082 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KND93970.1 - 0.0036 17.2 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KND93970.1 - 0.12 12.0 0.4 0.24 11.1 0.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAT PF02259.18 KND93972.1 - 2.3e-77 260.3 7.6 5e-77 259.2 5.3 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KND93972.1 - 5.3e-24 84.9 0.3 2.5e-23 82.7 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KND93972.1 - 1.1e-08 34.3 0.2 2.6e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain Urb2 PF10441.4 KND93972.1 - 0.0013 18.4 0.8 0.32 10.5 0.1 4.0 3 1 0 3 3 3 1 Urb2/Npa2 family TPR_2 PF07719.12 KND93972.1 - 0.002 17.8 1.5 0.43 10.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND93972.1 - 0.014 15.1 2.0 2 8.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND93972.1 - 0.023 14.3 1.6 4.1 7.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AIG2 PF06094.7 KND93973.1 - 1.2e-17 64.2 0.1 1.8e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family DUF1757 PF08560.5 KND93974.1 - 0.041 13.5 0.2 0.82 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1757) AMP-binding PF00501.23 KND93975.1 - 1.8e-40 138.6 0.0 2.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SMI1_KNR4 PF09346.5 KND93976.1 - 2.2e-33 115.0 0.0 3.6e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.9 KND93977.1 - 1.4e-48 164.1 1.3 5.3e-48 162.2 0.9 2.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KND93977.1 - 6.4e-11 41.6 1.7 6.4e-11 41.6 1.2 1.6 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Phage_GP20 PF06810.6 KND93977.1 - 0.018 14.5 0.3 0.045 13.1 0.2 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 Sec5 PF15469.1 KND93977.1 - 0.049 13.3 0.5 0.15 11.7 0.3 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF3829 PF12889.2 KND93977.1 - 0.06 12.5 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) YcbB PF08664.5 KND93977.1 - 0.084 12.6 0.2 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 YcbB domain Chitin_bind_3 PF03067.10 KND93978.1 - 5.4e-05 23.5 0.0 9.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 KND93978.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3433 PF11915.3 KND93979.1 - 7.3e-38 128.6 14.7 6.2e-24 83.9 0.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Metallophos PF00149.23 KND93980.1 - 1.4e-13 50.7 0.7 2.3e-13 50.0 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Latarcin PF10279.4 KND93980.1 - 0.049 13.8 0.0 11 6.3 0.0 2.4 2 1 0 2 2 2 0 Latarcin precursor Pet127 PF08634.5 KND93981.1 - 1.1e-118 395.3 1.4 1.6e-118 394.8 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Iso_dh PF00180.15 KND93982.1 - 7.8e-84 281.5 0.0 9.1e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pol_alpha_B_N PF08418.5 KND93983.1 - 5.4e-56 189.9 0.0 7.1e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KND93983.1 - 1.3e-40 138.9 0.0 2.5e-40 137.9 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Rop-like PF05082.8 KND93983.1 - 0.072 12.5 0.1 0.25 10.8 0.0 1.9 1 0 0 1 1 1 0 Rop-like Prp19_bind PF06991.6 KND93984.1 - 2.5e-42 145.0 32.5 2.5e-42 145.0 22.6 2.2 1 1 1 2 2 2 2 Splicing factor, Prp19-binding domain Ndc1_Nup PF09531.5 KND93984.1 - 5.6 5.2 5.1 7.4 4.8 3.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GATA PF00320.22 KND93985.1 - 0.00017 20.8 1.7 0.36 10.2 0.1 2.6 2 0 0 2 2 2 2 GATA zinc finger polyprenyl_synt PF00348.12 KND93987.1 - 6.3e-67 225.1 0.0 7.6e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 KND93988.1 - 4.2e-51 172.4 0.7 1.1e-50 171.1 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KND93988.1 - 2.1e-19 68.2 5.4 7.5e-05 22.1 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KND93988.1 - 1.2e-17 63.2 10.2 2.1e-06 27.2 0.0 6.8 5 1 2 7 7 7 4 TPR repeat TPR_8 PF13181.1 KND93988.1 - 7.7e-14 50.3 7.6 0.0031 17.1 0.0 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND93988.1 - 3.2e-11 42.2 16.1 0.045 13.6 0.0 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND93988.1 - 1.1e-08 35.5 18.5 7.3e-05 23.3 0.0 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND93988.1 - 1.5e-08 34.4 17.4 0.00013 21.8 0.2 6.1 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND93988.1 - 2e-08 34.1 16.0 0.069 13.8 0.0 8.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND93988.1 - 3.9e-05 23.5 0.5 2.4 8.5 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KND93988.1 - 5e-05 23.3 4.3 0.3 11.2 0.1 4.7 3 1 2 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KND93988.1 - 0.00013 21.5 5.4 0.064 13.0 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.2 KND93988.1 - 0.028 14.2 5.8 0.072 12.9 0.1 3.4 2 1 2 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.1 KND93988.1 - 0.033 14.0 15.1 7 6.5 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND93988.1 - 0.037 14.3 16.0 9.8 6.6 0.0 6.5 7 1 0 7 7 6 0 Tetratricopeptide repeat DUF2424 PF10340.4 KND93988.1 - 0.073 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) TPR_6 PF13174.1 KND93988.1 - 0.088 13.3 24.3 5.3 7.7 0.2 9.1 11 0 0 11 11 10 0 Tetratricopeptide repeat RmlD_sub_bind PF04321.12 KND93989.1 - 6.1e-51 172.9 0.1 7.4e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KND93989.1 - 5e-21 75.2 0.0 8.8e-21 74.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND93989.1 - 5e-10 38.7 0.2 3.1e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KND93989.1 - 5.8e-09 35.2 0.5 6.5e-06 25.2 0.0 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KND93989.1 - 3.2e-06 27.2 0.2 4.6e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND93989.1 - 2.6e-05 23.0 0.0 9e-05 21.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KND93989.1 - 9.4e-05 22.3 2.6 0.013 15.3 1.8 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND93989.1 - 0.036 13.7 3.0 3.2 7.3 0.2 2.5 1 1 0 2 2 2 0 KR domain PH PF00169.24 KND93990.1 - 0.03 14.5 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 PH domain DHFR_2 PF06442.6 KND93991.1 - 0.084 12.5 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 R67 dihydrofolate reductase Vps54 PF07928.7 KND93992.1 - 4.8e-46 156.2 0.7 8.7e-46 155.4 0.0 1.8 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KND93992.1 - 8.6e-06 24.8 0.6 2e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KND93992.1 - 0.0068 16.0 0.3 0.15 11.6 0.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 KND93992.1 - 0.22 11.3 2.1 0.61 9.9 0.5 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LUC7 PF03194.10 KND93992.1 - 0.61 9.5 4.3 0.27 10.7 1.0 1.8 2 0 0 2 2 2 0 LUC7 N_terminus DUF904 PF06005.7 KND93992.1 - 0.97 9.7 6.0 0.21 11.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Y_phosphatase2 PF03162.8 KND93994.1 - 4.6e-42 143.1 0.0 6.8e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KND93994.1 - 7.8e-11 42.4 0.0 1e-08 35.5 0.0 2.2 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 KND93994.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KND93994.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain NAD_binding_6 PF08030.7 KND93995.1 - 1.1e-11 44.9 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KND93995.1 - 0.13 12.8 0.0 0.85 10.2 0.0 2.3 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain Iron_permease PF04120.7 KND93996.1 - 5.1e-35 119.9 15.6 9.7e-20 70.5 0.0 4.2 3 1 1 4 4 4 4 Low affinity iron permease Ank_2 PF12796.2 KND93997.1 - 9.9e-87 285.4 9.3 4.3e-23 81.4 0.0 5.6 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KND93997.1 - 3.8e-70 228.3 2.6 1.1e-06 28.1 0.0 12.3 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 KND93997.1 - 2.9e-53 177.3 0.2 6.7e-09 36.0 0.0 7.2 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND93997.1 - 2.5e-51 166.4 0.2 0.00014 21.7 0.0 11.7 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 KND93997.1 - 2.2e-40 135.7 12.8 8.2e-07 29.0 0.1 9.6 1 1 10 11 11 11 9 Ankyrin repeats (many copies) Clr5 PF14420.1 KND93997.1 - 2.3e-13 49.7 3.5 4.7e-13 48.8 2.4 1.5 1 0 0 1 1 1 1 Clr5 domain DUF1843 PF08898.5 KND93997.1 - 0.00021 21.2 8.2 18 5.4 0.0 5.9 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) Rbsn PF11464.3 KND93997.1 - 0.00055 19.4 0.1 6.3 6.4 0.0 4.6 5 0 0 5 5 5 1 Rabenosyn Rab binding domain R3H PF01424.17 KND93997.1 - 0.015 14.9 1.4 4.2 7.1 0.0 4.4 5 0 0 5 5 5 0 R3H domain AAA PF00004.24 KND93998.1 - 4.5e-34 117.5 0.0 6.4e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND93998.1 - 8.3e-09 35.6 0.5 5.1e-07 29.8 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND93998.1 - 5.4e-07 29.8 0.2 0.00014 22.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND93998.1 - 7.4e-07 28.9 0.0 2.6e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KND93998.1 - 3e-06 27.1 0.0 5.4e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND93998.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KND93998.1 - 4.9e-05 22.3 0.0 6.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KND93998.1 - 5.7e-05 23.9 0.0 0.00012 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KND93998.1 - 9.5e-05 22.5 0.0 0.00021 21.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KND93998.1 - 0.00032 20.3 0.2 0.0009 18.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KND93998.1 - 0.00037 19.9 0.4 0.05 12.9 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 KND93998.1 - 0.00049 19.6 0.1 0.49 9.7 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain AAA_28 PF13521.1 KND93998.1 - 0.00054 19.9 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KND93998.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KND93998.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND93998.1 - 0.0026 16.8 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KND93998.1 - 0.0044 16.2 0.1 0.0086 15.2 0.0 1.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KND93998.1 - 0.0048 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND93998.1 - 0.0052 16.3 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KND93998.1 - 0.007 16.0 0.0 0.13 11.9 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 KND93998.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SRPRB PF09439.5 KND93998.1 - 0.012 14.8 0.1 0.024 13.8 0.0 1.5 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KND93998.1 - 0.014 15.7 0.0 0.047 13.9 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 KND93998.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KND93998.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 KND93998.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 KND93998.1 - 0.047 13.1 0.3 0.98 8.8 0.2 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 KND93998.1 - 0.047 13.3 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KND93998.1 - 0.057 12.8 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KND93998.1 - 0.058 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein NACHT PF05729.7 KND93998.1 - 0.06 13.0 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 KND93998.1 - 0.061 12.2 0.3 0.98 8.3 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KND93998.1 - 0.062 12.8 0.1 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KND93998.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KND93998.1 - 0.092 12.2 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Pkinase PF00069.20 KND93999.1 - 2e-17 63.2 0.0 1.5e-15 57.0 0.0 3.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND93999.1 - 0.016 14.3 0.0 0.062 12.3 0.0 1.9 2 1 1 3 3 3 0 Protein tyrosine kinase adh_short PF00106.20 KND94000.1 - 6.1e-16 58.7 0.4 1.7e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND94000.1 - 2e-06 27.5 0.1 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND94000.1 - 7.8e-05 22.7 0.1 0.00012 22.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND94000.1 - 0.0043 16.5 0.2 0.0093 15.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND94000.1 - 0.0093 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 KND94000.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 KND94000.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FMN_bind_2 PF04299.7 KND94001.1 - 5.7e-53 178.8 0.0 6.8e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain NmrA PF05368.8 KND94002.1 - 5.2e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND94002.1 - 5.6e-09 36.2 0.0 8.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND94002.1 - 0.0081 14.9 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family APOBEC_C PF05240.9 KND94002.1 - 0.053 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Cnl2_NKP2 PF09447.5 KND94003.1 - 2.5e-19 68.6 0.0 5.3e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Citrate_synt PF00285.16 KND94004.1 - 2.3e-18 66.0 0.0 9.2e-16 57.5 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KND94004.1 - 7.5e-18 64.8 0.1 2.3e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KND94004.1 - 7.4e-15 54.8 0.1 1.3e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KND94004.1 - 5.8e-05 22.7 0.0 0.0007 19.2 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.15 KND94005.1 - 1.7e-15 56.2 0.0 2.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e ATP-grasp_2 PF08442.5 KND94006.1 - 3e-07 30.0 0.0 4.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Guanylate_kin PF00625.16 KND94007.1 - 2.4e-63 212.8 0.0 2.9e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KND94007.1 - 6.1e-05 22.9 0.3 0.00048 20.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND94007.1 - 0.00015 22.0 0.1 0.0012 19.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND94007.1 - 0.00032 19.9 0.0 0.00066 18.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND94007.1 - 0.0024 17.9 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KND94007.1 - 0.004 17.1 0.1 0.2 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND94007.1 - 0.0096 16.7 0.2 0.022 15.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND94007.1 - 0.019 14.9 0.0 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF1895 PF08988.5 KND94007.1 - 0.039 13.9 0.2 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) ABC_tran PF00005.22 KND94007.1 - 0.054 13.7 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 KND94007.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KND94007.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.12 KND94007.1 - 0.082 12.2 0.0 2.2 7.6 0.0 2.2 1 1 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.1 KND94007.1 - 0.089 12.3 0.0 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KND94007.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Nop PF01798.13 KND94008.1 - 7.8e-55 184.2 0.3 3.9e-54 182.0 0.2 2.0 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KND94008.1 - 7.9e-25 86.4 0.1 1.3e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KND94008.1 - 5.1e-20 71.4 2.1 5.1e-20 71.4 1.5 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Med19 PF10278.4 KND94008.1 - 4.4 6.9 35.9 0.075 12.6 12.2 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 vATP-synt_AC39 PF01992.11 KND94009.1 - 1.9e-116 388.9 0.0 2.1e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF1777 PF08648.7 KND94010.1 - 0.00011 22.0 0.4 0.00032 20.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) KxDL PF10241.4 KND94011.1 - 2.5e-21 75.3 0.3 3.5e-21 74.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.6 KND94011.1 - 0.094 12.1 0.2 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism Cir_N PF10197.4 KND94013.1 - 0.0024 17.8 2.0 0.0024 17.8 1.4 4.9 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Aldedh PF00171.17 KND94013.1 - 1.2 7.3 3.6 1.8 6.7 2.5 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family RasGEF PF00617.14 KND94015.1 - 1.3e-49 168.5 0.6 2e-49 167.9 0.4 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KND94015.1 - 7.5e-13 48.4 0.2 1.8e-12 47.2 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA PF00004.24 KND94016.1 - 6.9e-49 165.4 0.0 1.6e-37 128.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND94016.1 - 2e-10 40.8 0.0 0.00013 22.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND94016.1 - 1.5e-08 34.8 0.0 0.0012 18.9 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KND94016.1 - 1.5e-07 31.3 0.0 0.0092 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KND94016.1 - 5.2e-07 29.1 0.2 8.2e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 KND94016.1 - 9.3e-07 27.8 0.0 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 KND94016.1 - 1.4e-06 28.1 0.1 0.49 10.0 0.0 4.1 2 2 1 4 4 4 1 Archaeal ATPase AAA_2 PF07724.9 KND94016.1 - 4.2e-06 26.7 0.0 7.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KND94016.1 - 7.1e-06 25.7 0.0 0.00073 19.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KND94016.1 - 8.3e-06 26.6 0.0 0.011 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain CDC48_N PF02359.13 KND94016.1 - 9.5e-06 25.4 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.1 KND94016.1 - 2.4e-05 24.6 0.0 0.017 15.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KND94016.1 - 3.3e-05 24.0 0.0 0.055 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KND94016.1 - 3.5e-05 23.7 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KND94016.1 - 0.00011 21.8 0.2 0.023 14.4 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 KND94016.1 - 0.00019 20.5 0.1 0.072 12.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KND94016.1 - 0.00031 19.9 0.5 0.0056 15.8 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KND94016.1 - 0.00043 19.7 0.2 0.18 11.2 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 KND94016.1 - 0.0012 18.3 3.3 0.26 10.6 0.0 3.5 2 2 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KND94016.1 - 0.0018 18.2 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KND94016.1 - 0.0042 16.2 0.5 0.01 14.9 0.1 1.8 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 KND94016.1 - 0.0047 15.8 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 KND94016.1 - 0.0081 15.7 0.0 0.043 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KND94016.1 - 0.011 15.3 2.0 10 5.7 0.0 3.6 4 0 0 4 4 3 0 NACHT domain Sigma54_activat PF00158.21 KND94016.1 - 0.022 14.2 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 KND94016.1 - 0.042 13.0 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 KND94016.1 - 0.044 14.0 0.2 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KND94016.1 - 0.12 11.1 0.7 1.4 7.7 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.11 KND94016.1 - 0.13 11.4 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 KND94016.1 - 0.14 11.0 0.0 0.47 9.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ribosomal_S15 PF00312.17 KND94017.1 - 3e-16 58.9 1.1 5.1e-16 58.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 KND94018.1 - 4.4e-43 146.9 0.1 2.3e-22 79.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Pga1 PF10333.4 KND94020.1 - 0.0058 16.3 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Ribosomal_S5_C PF03719.10 KND94021.1 - 1.5e-16 59.4 0.5 1.8e-15 55.9 0.0 2.5 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KND94021.1 - 3.1e-08 33.2 0.1 6.2e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Nckap1 PF09735.4 KND94022.1 - 0.0013 16.3 0.0 0.0014 16.1 0.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein OAD_gamma PF04277.8 KND94022.1 - 0.014 15.7 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ODV-E18 PF10717.4 KND94022.1 - 0.062 12.7 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 FtsX PF02687.16 KND94022.1 - 0.062 13.0 0.0 0.065 12.9 0.0 1.0 1 0 0 1 1 1 0 FtsX-like permease family TMEM154 PF15102.1 KND94022.1 - 0.087 12.5 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family RNA_pol_Rpc82 PF05645.8 KND94023.1 - 9.6e-49 166.2 0.1 2.1e-48 165.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KND94023.1 - 2.2e-12 46.6 0.8 1.5e-09 37.5 0.0 4.2 5 0 0 5 5 5 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KND94023.1 - 0.0069 15.8 0.0 3.4 7.2 0.0 3.3 3 0 0 3 3 3 2 TFIIE alpha subunit RIIa PF02197.12 KND94023.1 - 0.03 13.7 0.2 0.091 12.2 0.1 1.7 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Sec8_exocyst PF04048.9 KND94023.1 - 0.082 12.5 1.2 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MmoB_DmpM PF02406.12 KND94023.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 MmoB/DmpM family Mito_carr PF00153.22 KND94024.1 - 1.1e-18 66.6 0.1 2.3e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein LsmAD PF06741.8 KND94025.1 - 3.1e-19 68.8 0.5 3.1e-19 68.8 0.3 2.5 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16_C PF05193.16 KND94026.1 - 7.9e-15 54.9 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND94026.1 - 8.5e-15 54.8 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) WW PF00397.21 KND94027.1 - 2.8e-08 33.4 0.2 5.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 WW domain Macoilin PF09726.4 KND94027.1 - 0.56 8.4 9.4 0.68 8.1 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 KND94027.1 - 1.2 8.0 9.3 1.7 7.6 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CytochromB561_N PF09786.4 KND94027.1 - 1.4 7.3 8.2 1.9 6.8 5.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Lin-8 PF03353.10 KND94027.1 - 5.8 6.1 6.9 9 5.4 4.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glyco_hydro_61 PF03443.9 KND94028.1 - 0.066 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 AT_hook PF02178.14 KND94029.1 - 0.089 12.5 23.2 0.42 10.4 4.0 3.2 2 0 0 2 2 2 0 AT hook motif Meth_synt_2 PF01717.13 KND94030.1 - 6.9e-145 482.0 0.0 6.9e-140 465.6 0.0 2.7 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KND94030.1 - 5.3e-106 354.3 0.3 1.8e-91 306.6 0.0 4.1 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KND94030.1 - 0.00067 18.6 0.0 0.04 12.8 0.0 2.7 3 0 0 3 3 3 1 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.5 KND94030.1 - 0.059 13.2 2.6 0.21 11.5 1.8 1.9 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) MFS_1 PF07690.11 KND94032.1 - 1.3e-36 126.0 41.8 1.3e-36 126.0 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94032.1 - 2.1e-12 46.3 14.6 2.1e-12 46.3 10.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Ost4 PF10215.4 KND94033.1 - 1.4e-16 59.7 1.0 1.5e-16 59.5 0.7 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase zf-CCCH PF00642.19 KND94034.1 - 1e-06 28.2 0.8 2.8e-06 26.8 0.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CCDC-167 PF15188.1 KND94034.1 - 0.028 14.3 0.9 0.028 14.3 0.6 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-CCCH_2 PF14608.1 KND94034.1 - 3.9 7.6 11.1 4.1 7.5 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Mito_carr PF00153.22 KND94035.1 - 2.7e-42 142.3 7.2 3.7e-15 55.3 0.3 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Thr_synth_N PF14821.1 KND94036.1 - 6.3e-29 99.8 0.0 1.8e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KND94036.1 - 7e-21 74.7 0.0 4.3e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CS PF04969.11 KND94037.1 - 1.3e-10 41.6 0.0 2.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 CS domain DUF4202 PF13875.1 KND94037.1 - 0.097 12.3 0.5 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) RRM_1 PF00076.17 KND94038.1 - 1.3e-17 63.1 0.0 2.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94038.1 - 8.2e-13 48.1 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND94038.1 - 5.5e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KND94038.1 - 7.5e-05 23.0 1.9 7.5e-05 23.0 1.3 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 KND94038.1 - 0.003 17.6 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_3 PF08777.6 KND94038.1 - 0.077 12.8 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 RNA binding motif DUF2470 PF10615.4 KND94039.1 - 4e-19 68.6 0.0 6.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 KND94039.1 - 0.15 12.0 1.3 0.25 11.2 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Helicase_C PF00271.26 KND94040.1 - 5.1e-20 71.1 0.0 1.1e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KND94040.1 - 4.1e-14 52.4 0.0 9.6e-14 51.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SOG2 PF10428.4 KND94041.1 - 4.1e-98 328.9 0.1 4.1e-98 328.9 0.1 1.7 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 KND94041.1 - 1.8e-17 62.5 8.2 3e-07 29.9 0.1 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND94041.1 - 1.4e-15 56.7 6.2 3.1e-09 36.4 0.3 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KND94041.1 - 1.4e-09 36.6 5.3 0.19 11.8 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KND94041.1 - 8.4e-07 28.1 3.9 2.5 8.6 0.0 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KND94041.1 - 8.8e-05 22.1 0.4 3.5 7.9 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat DUF2408 PF10303.4 KND94041.1 - 0.031 14.3 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) GCN5L1 PF06320.8 KND94042.1 - 0.00018 21.3 0.5 0.00027 20.7 0.3 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Nucleoplasmin PF03066.10 KND94042.1 - 0.065 12.7 6.0 0.11 12.0 4.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin HAUS6_N PF14661.1 KND94042.1 - 0.18 11.1 2.3 0.26 10.6 1.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Filament PF00038.16 KND94043.1 - 4.5e-05 23.0 6.1 0.00045 19.7 4.0 2.0 1 1 0 1 1 1 1 Intermediate filament protein DUF972 PF06156.8 KND94043.1 - 0.0002 21.6 8.3 0.0009 19.5 2.4 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 KND94043.1 - 0.00038 20.1 6.3 0.0004 20.0 2.1 2.4 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region ATG16 PF08614.6 KND94043.1 - 0.00092 19.0 7.6 0.0016 18.3 5.3 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TSC22 PF01166.13 KND94043.1 - 0.0011 18.8 11.3 0.018 15.0 3.2 3.2 2 1 1 3 3 3 1 TSC-22/dip/bun family Reo_sigmaC PF04582.7 KND94043.1 - 0.0015 17.7 0.4 0.0021 17.3 0.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KND94043.1 - 0.0025 15.6 7.1 0.0031 15.3 4.9 1.2 1 0 0 1 1 1 1 Myosin tail ADIP PF11559.3 KND94043.1 - 0.0042 16.9 10.4 0.41 10.5 4.8 2.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 KND94043.1 - 0.0057 16.2 11.1 0.14 11.7 0.4 2.3 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 DUF904 PF06005.7 KND94043.1 - 0.0058 16.8 8.7 0.022 15.0 2.2 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF904) HALZ PF02183.13 KND94043.1 - 0.006 16.2 11.6 0.21 11.3 2.4 3.4 3 0 0 3 3 3 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 KND94043.1 - 0.0062 16.4 18.3 0.033 14.1 4.2 4.2 4 1 1 5 5 5 1 bZIP transcription factor CASP_C PF08172.7 KND94043.1 - 0.01 14.8 1.9 0.1 11.5 0.3 2.2 2 0 0 2 2 2 0 CASP C terminal CCDC144C PF14915.1 KND94043.1 - 0.012 14.5 8.0 0.65 8.8 3.3 2.8 1 1 2 3 3 3 0 CCDC144C protein coiled-coil region TBPIP PF07106.8 KND94043.1 - 0.012 15.1 9.1 0.19 11.2 4.1 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 KND94043.1 - 0.013 14.9 10.5 0.043 13.2 3.1 3.1 2 1 1 3 3 3 0 Septum formation initiator Ax_dynein_light PF10211.4 KND94043.1 - 0.017 14.9 5.2 0.18 11.6 2.0 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Kinetocho_Slk19 PF12709.2 KND94043.1 - 0.024 14.6 7.9 1.5 8.9 1.8 2.8 2 1 0 2 2 2 0 Central kinetochore-associated TMF_TATA_bd PF12325.3 KND94043.1 - 0.036 13.7 4.5 0.039 13.6 1.1 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 KND94043.1 - 0.045 13.6 4.8 3.1 7.7 1.9 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 KND94043.1 - 0.051 12.6 10.0 0.071 12.1 4.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 RmuC PF02646.11 KND94043.1 - 0.055 12.2 1.8 1.8 7.3 0.1 2.2 2 0 0 2 2 2 0 RmuC family Striatin PF08232.7 KND94043.1 - 0.057 13.7 10.0 0.23 11.7 2.3 2.7 1 1 1 2 2 2 0 Striatin family DUF1090 PF06476.7 KND94043.1 - 0.063 12.9 9.9 0.045 13.4 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) TMF_DNA_bd PF12329.3 KND94043.1 - 0.072 12.9 9.1 0.093 12.5 2.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.8 KND94043.1 - 0.08 11.8 14.3 0.074 11.9 0.7 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Leu_zip PF15294.1 KND94043.1 - 0.089 11.8 8.7 0.48 9.4 5.4 2.2 1 1 0 1 1 1 0 Leucine zipper CENP-F_leu_zip PF10473.4 KND94043.1 - 0.11 12.3 8.0 0.86 9.4 2.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2570 PF10828.3 KND94043.1 - 0.11 12.0 4.9 0.18 11.4 3.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF3450 PF11932.3 KND94043.1 - 0.13 11.4 3.0 0.14 11.4 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.6 KND94043.1 - 0.14 11.9 2.2 0.26 11.1 0.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0449 PF15136.1 KND94043.1 - 0.14 12.3 8.3 1 9.5 2.3 3.0 2 1 1 3 3 2 0 Uncharacterised protein family UPF0449 Nnf1 PF03980.9 KND94043.1 - 0.22 11.5 6.9 2 8.4 1.8 2.9 2 1 0 2 2 2 0 Nnf1 TPR_MLP1_2 PF07926.7 KND94043.1 - 0.3 10.8 11.0 1.1 9.0 6.8 2.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.7 KND94043.1 - 0.32 10.9 0.2 0.32 10.9 0.1 3.0 1 1 2 3 3 3 0 MbeD/MobD like DUF2205 PF10224.4 KND94043.1 - 0.58 9.7 4.6 5.3 6.6 0.7 2.6 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4407 PF14362.1 KND94043.1 - 0.63 8.9 4.1 1.7 7.5 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KLRAQ PF10205.4 KND94043.1 - 0.68 9.9 7.2 0.37 10.8 1.7 2.6 3 0 0 3 3 2 0 Predicted coiled-coil domain-containing protein DUF724 PF05266.9 KND94043.1 - 0.72 9.4 4.5 2 7.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 KND94043.1 - 0.95 9.0 12.5 0.38 10.3 4.1 2.1 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 KND94043.1 - 1.3 9.2 5.4 4.4 7.5 3.7 2.1 1 1 0 1 1 1 0 Syntaxin Cep57_CLD_2 PF14197.1 KND94043.1 - 1.5 8.7 15.8 6 6.8 0.2 3.4 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin PF02996.12 KND94043.1 - 1.9 8.1 5.7 26 4.4 2.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit DivIVA PF05103.8 KND94043.1 - 2.1 8.3 7.9 8 6.5 1.7 2.9 1 1 1 2 2 2 0 DivIVA protein DUF3373 PF11853.3 KND94043.1 - 3.5 6.0 4.8 2.6 6.4 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) GAS PF13851.1 KND94043.1 - 3.7 6.6 9.9 2.5 7.2 3.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cut12 PF11500.3 KND94043.1 - 4.7 6.8 9.6 3.9 7.1 0.2 3.0 3 0 0 3 3 3 0 Spindle pole body formation-associated protein Rabaptin PF03528.10 KND94043.1 - 7.6 6.5 8.3 19 5.2 4.7 2.4 2 1 0 2 2 2 0 Rabaptin DUF3552 PF12072.3 KND94043.1 - 7.6 5.6 13.1 0.9 8.7 3.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) Bap31 PF05529.7 KND94043.1 - 9.8 5.5 6.8 7.8 5.9 1.6 2.3 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF2975 PF11188.3 KND94044.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF3112 PF11309.3 KND94044.1 - 0.57 9.9 5.4 1.3 8.7 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF1772 PF08592.6 KND94044.1 - 7.1 6.3 8.1 8.9 6.0 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF1304 PF06993.7 KND94045.1 - 2.2e-35 120.7 3.6 2.8e-35 120.4 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Fungal_trans PF04082.13 KND94046.1 - 4.5e-13 48.6 1.5 7.2e-13 47.9 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94046.1 - 2.8e-07 30.3 8.4 5.5e-07 29.3 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smg4_UPF3 PF03467.10 KND94047.1 - 3.5e-31 108.5 1.3 6.1e-31 107.7 0.0 2.1 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 KND94047.1 - 1.9e-06 27.7 0.0 0.00022 21.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND94047.1 - 5.3e-06 25.9 0.0 0.00022 20.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 KND94047.1 - 4.5 5.3 19.3 6.2 4.9 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2205 PF10224.4 KND94048.1 - 0.0081 15.7 2.2 0.0081 15.7 1.5 2.3 3 0 0 3 3 3 1 Predicted coiled-coil protein (DUF2205) DUF2968 PF11180.3 KND94048.1 - 0.022 14.1 3.1 0.043 13.2 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3166 PF11365.3 KND94048.1 - 0.04 14.3 6.1 0.034 14.5 2.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) Laminin_II PF06009.7 KND94048.1 - 0.15 11.8 3.5 0.066 12.9 0.7 1.7 2 0 0 2 2 2 0 Laminin Domain II Asp-B-Hydro_N PF05279.6 KND94048.1 - 4.4 7.0 13.1 7 6.4 9.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AATF-Che1 PF13339.1 KND94048.1 - 6.3 6.9 16.0 1e+02 3.0 11.1 2.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor HSP70 PF00012.15 KND94049.1 - 8.1e-16 57.0 0.2 1.4e-13 49.6 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 KND94049.1 - 0.029 13.6 1.3 0.66 9.2 0.0 2.6 2 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.20 KND94049.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family SR-25 PF10500.4 KND94051.1 - 0.28 10.6 7.2 0.45 9.9 5.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-F_leu_zip PF10473.4 KND94052.1 - 0.00046 20.0 5.2 0.00081 19.2 3.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KND94052.1 - 0.0034 16.6 1.9 0.0063 15.7 1.1 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 KND94052.1 - 0.0039 16.8 4.0 0.0068 16.0 2.8 1.4 1 0 0 1 1 1 1 Mnd1 family SF-assemblin PF06705.6 KND94052.1 - 0.01 14.9 1.8 0.016 14.3 1.3 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Myosin_tail_1 PF01576.14 KND94052.1 - 0.023 12.4 5.6 0.033 11.9 3.9 1.1 1 0 0 1 1 1 0 Myosin tail DUF2968 PF11180.3 KND94052.1 - 0.057 12.7 4.8 0.11 11.8 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Suppressor_APC PF11414.3 KND94052.1 - 0.097 12.4 1.9 0.15 11.8 0.6 1.9 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein TBPIP PF07106.8 KND94052.1 - 0.11 12.0 2.0 0.21 11.1 0.2 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RolB_RolC PF02027.12 KND94052.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family DivIVA PF05103.8 KND94052.1 - 0.18 11.8 4.9 0.31 11.0 0.3 2.5 1 1 1 2 2 2 0 DivIVA protein Bap31 PF05529.7 KND94052.1 - 0.44 9.9 3.2 0.72 9.2 2.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 KND94052.1 - 0.68 9.4 6.2 1.2 8.6 4.3 1.4 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 KND94052.1 - 0.94 7.6 5.4 1.5 6.9 3.8 1.2 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 KND94052.1 - 1.1 8.2 5.8 1.6 7.7 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 KND94052.1 - 3.9 7.0 7.5 2.6 7.6 0.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_S7 PF00177.16 KND94053.1 - 1.7e-40 137.9 1.3 2.1e-40 137.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DOCK-C2 PF14429.1 KND94054.1 - 4.2e-19 68.8 0.0 8.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.23 KND94054.1 - 2.7e-06 26.6 0.1 7.8e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KND94054.1 - 0.00048 19.6 0.0 0.0043 16.6 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KND94054.1 - 0.038 13.4 0.0 0.097 12.1 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain DUF1190 PF06693.6 KND94054.1 - 1.3 9.0 6.2 3 7.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) zf-CSL PF05207.8 KND94055.1 - 3.1e-26 90.6 1.2 3.7e-26 90.3 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 KND94055.1 - 0.056 12.7 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_4 PF14570.1 KND94055.1 - 0.06 12.9 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 KND94055.1 - 0.21 11.5 1.8 0.4 10.6 1.2 1.5 1 1 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KND94055.1 - 1.2 8.9 3.5 3.3 7.5 2.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.16 KND94057.1 - 1.3e-17 63.3 17.5 6.8e-12 45.0 2.2 3.3 3 0 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 KND94057.1 - 0.025 14.2 1.7 0.025 14.2 1.2 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 KND94057.1 - 2.8 7.2 6.1 30 3.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain ABC_membrane_2 PF06472.10 KND94058.1 - 1.5e-106 355.6 2.3 1.5e-106 355.6 1.6 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KND94058.1 - 7.9e-17 61.8 0.0 1.9e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND94058.1 - 0.00077 19.5 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND94058.1 - 0.014 15.4 0.8 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KND94058.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KND94058.1 - 0.088 11.9 0.0 0.58 9.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KND94058.1 - 0.098 12.3 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KND94058.1 - 0.099 11.8 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND94058.1 - 0.11 12.7 0.3 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ribosomal_S25 PF03297.10 KND94059.1 - 8.8e-40 134.9 4.7 9.5e-40 134.8 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KND94059.1 - 0.082 12.5 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 MarR family Acetyltransf_5 PF13444.1 KND94060.1 - 0.00091 19.7 0.0 0.041 14.4 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND94060.1 - 0.0015 18.5 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND94060.1 - 0.031 14.4 0.0 0.089 12.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4191 PF13829.1 KND94061.1 - 0.014 14.5 1.4 0.028 13.5 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Cyt-b5 PF00173.23 KND94062.1 - 1.7e-09 37.3 0.0 2.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.24 KND94063.1 - 2.1e-16 60.3 0.0 3.7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KND94063.1 - 4.1e-15 55.5 0.0 7.8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KND94063.1 - 2.3e-13 50.1 0.0 4.8e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KND94063.1 - 2.3e-09 36.5 0.0 2.2e-07 29.9 0.0 2.4 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KND94063.1 - 3.6e-07 30.3 0.2 2.1e-06 27.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND94063.1 - 9.9e-07 28.9 0.0 5.3e-06 26.5 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KND94063.1 - 2.7e-06 27.2 0.0 1.5e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KND94063.1 - 3.5e-06 26.6 0.0 9.4e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KND94063.1 - 1.4e-05 24.8 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND94063.1 - 1.6e-05 24.6 0.1 0.00021 20.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KND94063.1 - 4.7e-05 22.5 0.0 0.00013 21.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KND94063.1 - 4.7e-05 23.1 0.2 0.0002 21.1 0.1 2.1 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 KND94063.1 - 6e-05 22.6 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 KND94063.1 - 8.7e-05 21.5 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 KND94063.1 - 0.00017 21.2 0.0 0.0019 17.7 0.1 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KND94063.1 - 0.00024 20.7 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KND94063.1 - 0.00047 18.9 0.0 0.68 8.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF2075 PF09848.4 KND94063.1 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KND94063.1 - 0.0022 17.2 0.1 1.1 8.5 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein Sigma54_activat PF00158.21 KND94063.1 - 0.0037 16.7 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 KND94063.1 - 0.0041 16.9 0.0 0.039 13.7 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND94063.1 - 0.0055 16.2 0.1 0.072 12.5 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.1 KND94063.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KND94063.1 - 0.0076 15.6 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 KND94063.1 - 0.01 15.2 0.1 0.048 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 KND94063.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 KND94063.1 - 0.018 14.2 0.2 0.14 11.3 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KND94063.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KND94063.1 - 0.021 15.6 0.0 0.044 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KND94063.1 - 0.029 13.8 0.2 1.8 7.9 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain TK PF00265.13 KND94063.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase RNA_helicase PF00910.17 KND94063.1 - 0.032 14.3 0.0 0.074 13.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 KND94063.1 - 0.041 12.6 0.0 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain BTB_2 PF02214.17 KND94064.1 - 9e-06 25.8 0.1 0.003 17.7 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Mito_carr PF00153.22 KND94065.1 - 2.1e-64 213.2 6.5 3.6e-23 81.1 0.0 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein CRS1_YhbY PF01985.16 KND94066.1 - 0.009 15.9 0.1 0.013 15.5 0.0 1.1 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain CENP-X PF09415.5 KND94068.1 - 2.6e-24 84.8 0.2 4.2e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Peptidase_S10 PF00450.17 KND94069.1 - 0.027 13.6 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Peptidase_S10 PF00450.17 KND94070.1 - 2.7e-94 316.6 0.0 3e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KND94070.1 - 0.032 14.1 0.0 0.25 11.1 0.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Pro_isomerase PF00160.16 KND94071.1 - 3.7e-39 134.4 0.0 5.7e-39 133.8 0.0 1.2 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 KND94072.1 - 1.8e-17 63.7 0.1 4.4e-16 59.2 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 KND94073.1 - 2e-42 145.0 0.0 3.9e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_H2_suC PF08615.6 KND94073.1 - 0.77 9.6 5.4 1.7 8.4 3.7 1.8 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HSF_DNA-bind PF00447.12 KND94074.1 - 5.2e-28 97.2 0.4 1.3e-27 96.0 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding AATF-Che1 PF13339.1 KND94074.1 - 0.26 11.4 5.0 1.5 8.9 0.2 2.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor zf-ZPR1 PF03367.8 KND94074.1 - 0.62 9.2 1.8 0.58 9.2 0.1 1.8 2 0 0 2 2 2 0 ZPR1 zinc-finger domain zf-ZPR1 PF03367.8 KND94075.1 - 7.1e-102 337.3 0.0 7.9e-51 171.4 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.7 KND94075.1 - 1.1 9.0 4.6 11 5.9 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbons DUF866 PF05907.8 KND94076.1 - 5.5e-35 120.2 1.1 1.9e-25 89.2 0.5 3.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) tRNA_int_end_N2 PF12928.2 KND94077.1 - 5.7e-18 64.1 0.0 9.7e-18 63.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KND94077.1 - 0.0092 15.5 0.9 0.017 14.6 0.1 1.9 2 1 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Aldedh PF00171.17 KND94079.1 - 2.6e-184 612.8 1.0 2.9e-184 612.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2435 PF10363.4 KND94080.1 - 4.6e-14 52.0 1.2 2.8e-13 49.5 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KND94080.1 - 6.9e-14 50.9 0.3 1.8e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) Adaptin_N PF01602.15 KND94080.1 - 0.002 16.5 0.3 0.25 9.6 0.0 2.5 2 0 0 2 2 2 2 Adaptin N terminal region HTH_9 PF08221.6 KND94080.1 - 0.024 14.4 0.1 4.3 7.2 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF3969 PF13108.1 KND94080.1 - 0.064 12.9 0.6 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) DUF4115 PF13464.1 KND94081.1 - 0.75 9.4 4.3 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) CENP-Q PF13094.1 KND94082.1 - 4.1e-28 98.4 3.7 4.1e-28 98.4 2.5 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit MRG PF05712.8 KND94084.1 - 3.2e-54 182.7 0.0 5.2e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KND94084.1 - 2.1e-07 30.5 0.4 4.1e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_hydro_72 PF03198.9 KND94085.1 - 2.7e-108 361.7 0.1 3.3e-108 361.3 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase FlgD_ig PF13860.1 KND94085.1 - 0.0014 18.3 1.1 0.019 14.6 0.4 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain Cellulase PF00150.13 KND94085.1 - 0.013 14.7 0.2 0.073 12.2 0.2 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RNase_H PF00075.19 KND94086.1 - 1e-27 97.0 0.0 1.8e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 KND94086.1 - 2.2e-27 94.7 9.7 7.9e-15 54.6 0.4 2.7 3 0 0 3 3 3 2 Caulimovirus viroplasmin dCMP_cyt_deam_1 PF00383.17 KND94087.1 - 3.1e-08 33.1 0.1 6.8e-08 32.0 0.1 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 6PF2K PF01591.13 KND94088.1 - 4.4e-65 218.8 0.0 5.2e-45 153.2 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KND94088.1 - 2.6e-26 92.6 0.1 1.8e-24 86.6 0.0 3.0 3 1 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KND94088.1 - 2.2e-05 24.3 0.0 0.00024 21.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain CARD PF00619.16 KND94088.1 - 0.0031 17.3 0.1 0.0092 15.7 0.1 1.8 1 1 0 1 1 1 1 Caspase recruitment domain KTI12 PF08433.5 KND94088.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 KND94088.1 - 0.019 15.7 0.0 0.063 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KND94088.1 - 0.039 13.0 0.0 0.31 10.1 0.0 2.1 1 1 0 1 1 1 0 Zeta toxin Lipase_GDSL_3 PF14606.1 KND94088.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.27 KND94089.1 - 3.1e-42 140.9 5.1 9.4e-09 34.8 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.9 KND94089.1 - 6.4e-30 103.0 14.0 1.3e-29 102.0 9.7 1.5 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 KND94089.1 - 0.002 16.4 0.3 0.067 11.4 0.0 2.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain TPR_10 PF13374.1 KND94089.1 - 0.058 13.3 2.8 7.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.21 KND94090.1 - 1.3e-32 112.2 0.0 2e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KND94090.1 - 3.1e-11 42.2 0.0 4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 KND94091.1 - 1.5e-52 175.2 0.3 8.2e-18 63.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 KND94092.1 - 6e-47 159.9 0.5 2.2e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KND94092.1 - 5.7e-25 87.3 0.0 1.9e-24 85.6 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.7 KND94093.1 - 1.7e-50 171.1 0.0 2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Neugrin PF06413.6 KND94094.1 - 1.6e-11 44.4 0.4 1.6e-11 44.4 0.3 2.1 1 1 2 3 3 3 1 Neugrin MRP-L20 PF12824.2 KND94094.1 - 4.7e-07 29.9 4.8 8.6e-07 29.0 3.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 KND94094.1 - 0.042 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 HTH domain adh_short PF00106.20 KND94095.1 - 3.2e-30 105.2 3.1 6.2e-30 104.3 2.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND94095.1 - 2.5e-12 46.8 4.9 2.9e-11 43.3 3.4 2.5 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KND94095.1 - 2.1e-11 44.0 0.0 3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CENP-N PF05238.8 KND94096.1 - 3.2e-120 401.8 0.0 3.8e-120 401.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 KND94097.1 - 2.7e-12 46.2 9.7 5e-12 45.4 6.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KND94097.1 - 0.00055 19.8 13.2 0.0029 17.5 9.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 KND94097.1 - 0.016 15.1 3.4 0.031 14.1 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.13 KND94097.1 - 0.047 13.6 0.4 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 KND94097.1 - 2.7 8.3 8.4 0.64 10.3 3.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KND94097.1 - 3.3 7.2 6.6 4.4 6.8 4.6 1.3 1 0 0 1 1 1 0 IncA protein Ribonuc_red_lgC PF02867.10 KND94098.1 - 1.3e-221 736.8 0.0 1.9e-221 736.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KND94098.1 - 7.6e-25 86.5 0.0 1.9e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KND94098.1 - 6.7e-16 58.5 0.0 4.3e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 KND94098.1 - 0.041 11.9 0.0 0.068 11.2 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MMR_HSR1_C PF08438.5 KND94098.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 GTPase of unknown function C-terminal TatD_DNase PF01026.16 KND94099.1 - 3.1e-49 167.4 0.0 8e-49 166.1 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase Pirin PF02678.11 KND94100.1 - 1.4e-31 108.4 0.0 6e-31 106.4 0.0 1.9 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 KND94100.1 - 1.4e-24 86.1 0.0 7e-24 83.8 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KND94100.1 - 1.5e-07 30.7 2.8 1.4e-05 24.4 0.7 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KND94100.1 - 0.011 15.0 0.2 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CFEM PF05730.6 KND94101.1 - 7e-08 32.1 6.2 1.3e-07 31.3 4.3 1.5 1 0 0 1 1 1 1 CFEM domain DUF4244 PF14029.1 KND94101.1 - 6.8 5.8 10.5 5.3 6.2 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) DENN PF02141.16 KND94102.1 - 7.3e-40 136.6 0.1 1.2e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KND94102.1 - 9.2e-06 25.5 0.1 4.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.6 KND94102.1 - 0.012 15.9 6.6 0.012 15.9 4.6 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PCRF PF03462.13 KND94102.1 - 0.22 11.2 3.0 1.7 8.4 0.2 2.5 2 0 0 2 2 2 0 PCRF domain Perilipin PF03036.11 KND94103.1 - 0.00037 19.4 0.0 0.00048 19.0 0.0 1.2 1 0 0 1 1 1 1 Perilipin family EF-hand_4 PF12763.2 KND94104.1 - 1.5e-34 117.8 0.0 1.6e-12 47.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 KND94104.1 - 2.8e-07 30.1 0.0 7.6e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 KND94104.1 - 6e-06 26.2 0.0 0.0069 16.4 0.0 3.4 2 1 0 2 2 2 1 EF-hand domain pair DUF3584 PF12128.3 KND94104.1 - 0.0032 14.9 22.2 0.0045 14.3 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) WEMBL PF05701.6 KND94104.1 - 0.02 13.3 18.9 0.029 12.8 13.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 KND94104.1 - 0.037 11.7 22.3 0.059 11.1 15.5 1.2 1 0 0 1 1 1 0 Myosin tail AAA_27 PF13514.1 KND94104.1 - 0.048 11.3 16.4 0.071 10.7 11.4 1.1 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.6 KND94104.1 - 0.063 13.1 29.2 0.5 10.1 10.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KND94104.1 - 0.069 13.0 25.7 0.057 13.2 3.6 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.7 KND94104.1 - 0.097 10.8 16.1 0.15 10.2 11.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 KND94104.1 - 0.16 11.7 27.2 1.2 8.9 9.7 2.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Prominin PF05478.6 KND94104.1 - 0.18 9.2 10.4 0.26 8.7 7.2 1.1 1 0 0 1 1 1 0 Prominin Spc7 PF08317.6 KND94104.1 - 0.43 9.2 24.2 1.2 7.6 8.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KND94104.1 - 0.73 9.3 29.2 1.8 8.1 15.2 2.2 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 KND94104.1 - 1.1 9.3 21.1 0.066 13.3 8.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KND94104.1 - 1.1 8.3 10.4 0.42 9.7 1.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 KND94104.1 - 2.3 5.9 11.4 3.6 5.3 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 KND94104.1 - 2.9 7.6 11.6 0.57 9.9 3.9 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 KND94104.1 - 3 6.8 26.1 0.86 8.5 7.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 KND94104.1 - 3.2 6.8 25.4 5.4 6.1 3.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KND94104.1 - 3.3 7.6 31.6 1.1 9.1 3.3 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 KND94104.1 - 3.9 5.8 19.6 11 4.3 13.5 1.4 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KND94104.1 - 4 7.0 26.6 8.1 6.0 5.7 2.3 1 1 1 2 2 2 0 Mnd1 family zf-C4H2 PF10146.4 KND94104.1 - 5.3 7.0 18.0 0.2 11.6 4.7 3.6 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3450 PF11932.3 KND94104.1 - 6.1 6.0 26.7 2.8 7.1 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4047 PF13256.1 KND94104.1 - 8.9 6.2 9.8 3.5 7.6 4.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Fmp27_WPPW PF10359.4 KND94104.1 - 9.8 4.4 19.5 0.56 8.5 1.6 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain zf-HIT PF04438.11 KND94105.1 - 4.5e-08 32.5 9.6 9e-08 31.6 6.6 1.5 1 0 0 1 1 1 1 HIT zinc finger VTC PF09359.5 KND94106.1 - 8.9e-90 300.5 0.1 1.5e-89 299.7 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KND94106.1 - 3.6e-18 66.3 8.5 5.2e-09 36.2 0.5 3.3 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 KND94106.1 - 2.7e-08 33.8 3.0 2.7e-08 33.8 2.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glu_synthase PF01645.12 KND94107.1 - 6.5e-151 502.4 0.0 1.7e-150 501.0 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KND94107.1 - 3.5e-140 466.8 0.0 4.7e-140 466.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KND94107.1 - 1.2e-115 385.7 0.0 2.4e-115 384.7 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KND94107.1 - 1.3e-67 226.7 1.1 2.3e-67 225.8 0.8 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KND94107.1 - 1.5e-22 79.3 0.1 3e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KND94107.1 - 3.1e-14 53.3 0.0 8.5e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND94107.1 - 2.1e-08 34.4 0.2 0.0063 16.5 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND94107.1 - 5.1e-08 32.8 0.1 2e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND94107.1 - 1.1e-07 32.1 0.0 0.00018 21.8 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KND94107.1 - 4.8e-05 22.6 0.2 9.7e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KND94107.1 - 6.6e-05 21.5 0.1 0.00013 20.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KND94107.1 - 0.00024 20.1 0.1 0.00086 18.2 0.1 2.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KND94107.1 - 0.0004 19.6 0.0 0.0008 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND94107.1 - 0.0044 15.9 0.1 0.01 14.6 0.0 1.7 2 0 0 2 2 1 1 FAD binding domain Thi4 PF01946.12 KND94107.1 - 0.019 14.0 0.0 0.057 12.5 0.0 1.7 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 KND94107.1 - 0.034 13.8 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.13 KND94107.1 - 0.048 12.4 0.9 0.3 9.8 0.7 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FAD_binding_3 PF01494.14 KND94107.1 - 0.052 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GATase_6 PF13522.1 KND94107.1 - 0.057 13.3 0.1 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain NAD_binding_7 PF13241.1 KND94107.1 - 0.066 13.4 0.3 23 5.2 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1048 PF06304.6 KND94107.1 - 0.084 13.1 0.2 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) FMO-like PF00743.14 KND94107.1 - 0.098 10.8 0.1 2.1 6.4 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.17 KND94107.1 - 0.11 11.3 1.1 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 KND94107.1 - 0.11 11.8 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 1 0 Ketopantoate reductase PanE/ApbA FGGY_C PF02782.11 KND94108.1 - 1.7e-48 164.8 0.8 2.1e-48 164.5 0.1 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KND94108.1 - 1.5e-26 93.2 0.5 8.6e-25 87.4 0.0 3.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 KND94108.1 - 0.023 14.0 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Hexokinase BcrAD_BadFG PF01869.15 KND94108.1 - 0.068 12.4 0.1 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3425 PF11905.3 KND94110.1 - 1.4e-32 112.4 0.4 2.5e-32 111.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KND94110.1 - 0.0017 18.2 7.3 0.0037 17.1 5.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Nic96 PF04097.9 KND94111.1 - 2.2e-206 686.7 0.0 2.6e-206 686.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KND94111.1 - 5.7e-16 58.7 81.2 1.4e-11 44.6 29.4 4.1 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF1129 PF06570.6 KND94111.1 - 6.2 6.0 5.9 57 2.9 4.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Cation_ATPase_N PF00690.21 KND94112.1 - 3.2e-10 39.3 0.5 2.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 KND94113.1 - 4.5e-63 212.3 7.7 9.4e-63 211.3 5.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND94113.1 - 8.6e-23 81.8 0.0 1.6e-22 80.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND94113.1 - 2e-12 47.7 0.0 5.3e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND94113.1 - 0.0011 18.6 0.1 0.0044 16.6 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND94113.1 - 0.21 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Citrate_synt PF00285.16 KND94114.1 - 6.5e-101 337.6 0.0 7.7e-101 337.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KND94114.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone RRM_5 PF13893.1 KND94115.1 - 1.7e-06 27.7 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND94115.1 - 6.8e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94115.1 - 1.7e-05 24.7 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KND94115.1 - 0.00064 19.9 0.0 0.0021 18.2 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. TPR_11 PF13414.1 KND94116.1 - 0.00078 19.0 0.8 0.34 10.6 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 KND94116.1 - 0.067 13.4 0.4 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 KND94117.1 - 3.3e-35 120.0 1.5 3.3e-35 120.0 1.0 1.6 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.24 KND94117.1 - 0.0021 17.7 0.5 0.0055 16.3 0.4 1.8 1 0 0 1 1 1 1 KOW motif ECM11 PF15463.1 KND94117.1 - 0.1 12.9 0.4 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 Extracellular mutant protein 11 RabGAP-TBC PF00566.13 KND94120.1 - 6.8e-34 117.2 0.0 1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIL PF01843.14 KND94121.1 - 1.4e-19 69.9 5.3 3.8e-13 49.2 0.3 2.8 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 KND94121.1 - 4.1e-19 68.7 0.1 1.2e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KND94121.1 - 4.7e-16 57.7 0.1 1.2e-07 31.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KND94121.1 - 3.5e-15 56.0 0.1 4.1e-07 30.3 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND94121.1 - 1.4e-11 44.2 0.0 1.8e-06 27.9 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94121.1 - 1.5e-11 43.3 0.1 0.0013 18.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat TPT PF03151.11 KND94122.1 - 1.8e-27 95.9 15.2 1.8e-27 95.9 10.5 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KND94122.1 - 0.0002 20.4 27.0 0.0002 20.4 18.7 2.3 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.15 KND94122.1 - 0.0019 18.2 35.2 0.011 15.7 8.3 2.8 3 0 0 3 3 3 2 EamA-like transporter family OppC_N PF12911.2 KND94122.1 - 0.049 12.9 0.2 0.049 12.9 0.1 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C NAD_binding_8 PF13450.1 KND94123.1 - 8.8e-08 32.0 0.0 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KND94123.1 - 1.7e-07 30.7 0.0 8.5e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KND94123.1 - 0.07 13.0 0.0 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Noggin PF05806.7 KND94124.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Noggin HATPase_c PF02518.21 KND94125.1 - 1.5e-28 98.6 0.0 3.6e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KND94125.1 - 5.3e-21 74.7 0.0 1.4e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KND94125.1 - 3.6e-19 68.5 0.4 1.4e-18 66.6 0.3 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KND94125.1 - 3.7e-11 43.3 0.0 2.9e-10 40.4 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KND94125.1 - 7.7e-11 42.6 0.0 2.4e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KND94125.1 - 2.2e-06 27.7 0.0 5.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KND94125.1 - 3.7e-06 26.2 0.0 7.4e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_11 PF13414.1 KND94125.1 - 0.00085 18.9 4.9 0.099 12.3 0.2 3.3 3 0 0 3 3 3 2 TPR repeat HATPase_c_3 PF13589.1 KND94125.1 - 0.00099 18.7 0.1 0.0043 16.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.1 KND94125.1 - 0.017 14.8 2.4 4.1 7.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND94125.1 - 0.028 14.7 1.0 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NB-ARC PF00931.17 KND94125.1 - 0.039 12.8 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TPR_1 PF00515.23 KND94125.1 - 5.3 6.8 5.7 2.2 8.0 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PUF PF00806.14 KND94126.1 - 1.6e-39 131.1 0.1 2.8e-06 26.4 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat MRP-S33 PF08293.6 KND94127.1 - 1.7e-25 88.7 0.1 1.9e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Amidoligase_2 PF12224.3 KND94128.1 - 1.9e-05 24.4 0.1 5.2e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Putative amidoligase enzyme Ribonuclease_3 PF00636.21 KND94130.1 - 7.2e-14 52.2 0.0 1.6e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KND94130.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KND94130.1 - 0.031 14.8 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif F-box PF00646.28 KND94131.1 - 0.0018 17.8 0.1 0.0043 16.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KND94131.1 - 0.0033 17.1 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF4414 PF14377.1 KND94132.1 - 0.022 14.6 10.8 0.51 10.2 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) DUF763 PF05559.6 KND94132.1 - 0.076 11.9 0.1 0.076 11.9 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF763) CAP_N PF01213.14 KND94132.1 - 0.27 10.4 9.6 0.57 9.4 6.6 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Neur_chan_memb PF02932.11 KND94132.1 - 0.37 10.6 2.9 0.76 9.6 1.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BRF1 PF07741.8 KND94132.1 - 3.9 7.7 9.2 26 5.1 0.1 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF3306 PF11748.3 KND94132.1 - 4.5 7.9 16.3 2.4 8.8 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Molybdopterin PF00384.17 KND94133.1 - 7.6e-75 252.2 0.0 3.4e-73 246.8 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KND94133.1 - 3e-19 68.5 0.4 9.3e-19 67.0 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KND94133.1 - 4.7e-19 67.3 0.1 1.3e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KND94133.1 - 1.2e-14 54.1 0.0 3.3e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KND94133.1 - 8.7e-09 35.0 0.6 8.7e-09 35.0 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KND94133.1 - 0.025 14.3 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 KND94133.1 - 0.1 12.2 1.1 3.1 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ACBP PF00887.14 KND94135.1 - 1.6e-30 104.5 0.0 3.2e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Fungal_trans PF04082.13 KND94136.1 - 1.1e-24 86.7 0.4 1.5e-24 86.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94136.1 - 0.046 13.6 6.0 0.11 12.3 4.2 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_C PF02803.13 KND94137.1 - 1.3e-10 40.7 1.6 2.6e-10 39.7 0.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KND94137.1 - 4.9e-07 29.3 0.1 1.8e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KND94137.1 - 1.5e-05 24.0 0.1 0.00014 20.9 0.0 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 KND94137.1 - 0.00051 19.8 1.3 0.021 14.6 0.0 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 KND94137.1 - 0.0024 17.4 0.2 0.0069 15.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KND94137.1 - 0.022 13.2 0.2 0.077 11.4 0.1 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Amino_oxidase PF01593.19 KND94138.1 - 8e-12 44.9 0.2 6.6e-05 22.1 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND94138.1 - 1.2e-10 41.2 0.1 2.6e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND94138.1 - 2.8e-06 26.4 0.2 0.00066 18.6 0.1 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KND94138.1 - 3.7e-05 23.8 0.0 0.014 15.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND94138.1 - 0.00037 20.3 0.0 0.37 10.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 KND94138.1 - 0.0072 14.8 0.0 1.2 7.5 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KND94138.1 - 0.011 15.6 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND94138.1 - 0.043 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CtaG_Cox11 PF04442.9 KND94139.1 - 4.5e-57 192.1 0.1 1.3e-56 190.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 NAD_binding_10 PF13460.1 KND94140.1 - 7.5e-19 68.4 0.0 3.6e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KND94140.1 - 0.0023 17.2 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KND94140.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LSM14 PF12701.2 KND94141.1 - 9.1e-32 108.7 0.0 2.1e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KND94141.1 - 8.8e-21 74.3 2.1 2.1e-20 73.2 1.5 1.7 1 0 0 1 1 1 1 FDF domain V-SNARE PF05008.10 KND94141.1 - 1.2e-18 67.0 2.8 2.8e-18 65.8 1.9 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KND94141.1 - 1.4e-18 66.6 2.4 3.4e-18 65.4 1.7 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus SM-ATX PF14438.1 KND94141.1 - 0.0015 18.3 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Sec20 PF03908.8 KND94141.1 - 0.011 15.3 0.3 0.025 14.2 0.2 1.5 1 0 0 1 1 1 0 Sec20 SET PF00856.23 KND94143.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 SET domain Herpes_gE PF02480.11 KND94145.1 - 0.011 14.0 0.0 0.018 13.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 KND94145.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Bacteriocin_IIc PF10439.4 KND94145.1 - 0.46 10.6 6.4 0.9 9.7 4.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 KND94145.1 - 5.4 6.7 7.8 11 5.6 5.4 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain RNA_pol_Rpb2_6 PF00562.23 KND94146.1 - 2.5e-119 398.4 0.0 4.2e-119 397.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KND94146.1 - 1.3e-51 174.4 0.4 2.2e-51 173.6 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KND94146.1 - 1e-29 102.5 0.3 2.6e-29 101.3 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KND94146.1 - 3.9e-29 101.4 0.1 1.1e-28 99.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KND94146.1 - 2.2e-21 75.3 0.0 4.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KND94146.1 - 1.7e-20 72.5 0.2 4.2e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KND94146.1 - 3e-11 43.1 0.5 7.9e-11 41.7 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-TFIIB PF13453.1 KND94146.1 - 0.068 12.3 0.1 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger RNase_HII PF01351.13 KND94147.1 - 1.8e-43 148.4 0.0 3.8e-43 147.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII Mif2_N PF15624.1 KND94148.1 - 4.9e-34 117.8 0.3 4.9e-34 117.8 0.2 3.6 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 KND94148.1 - 7.8e-33 112.3 0.1 1.2e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KND94148.1 - 4.4e-06 26.0 0.0 1.4e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Cupin domain TP53IP5 PF15331.1 KND94148.1 - 0.94 9.3 12.9 4.9 6.9 6.4 2.5 3 0 0 3 3 3 0 Cellular tumour antigen p53-inducible 5 DUF3128 PF11326.3 KND94149.1 - 3.3e-29 100.8 1.4 6.6e-29 99.8 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) bZIP_C PF12498.3 KND94149.1 - 2.6 9.3 6.6 3.9 8.7 4.5 1.3 1 0 0 1 1 1 0 Basic leucine-zipper C terminal HSP70 PF00012.15 KND94150.1 - 3.5e-258 857.4 8.2 1.4e-130 436.1 0.7 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KND94150.1 - 2.6e-15 55.8 0.0 8.6e-11 40.9 0.0 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 KND94150.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KND94150.1 - 0.013 14.5 0.0 0.041 12.9 0.0 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Actin PF00022.14 KND94150.1 - 0.016 13.6 0.0 0.24 9.7 0.0 2.3 1 1 0 1 1 1 0 Actin FtsA PF14450.1 KND94150.1 - 0.034 13.9 3.9 5 6.9 2.7 3.5 1 1 0 1 1 1 0 Cell division protein FtsA StbA PF06406.6 KND94150.1 - 0.07 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 StbA protein MFS_1 PF07690.11 KND94152.1 - 8e-20 70.8 10.7 1e-19 70.5 7.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94152.1 - 3.7e-06 25.7 8.9 5.1e-06 25.3 6.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter UbiA PF01040.13 KND94152.1 - 0.0012 18.0 6.6 0.018 14.2 4.6 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family ATG22 PF11700.3 KND94152.1 - 0.041 12.3 2.7 0.053 11.9 1.9 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF204 PF02659.10 KND94152.1 - 2.1 8.5 7.1 4.9 7.3 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF Carn_acyltransf PF00755.15 KND94153.1 - 1.8e-164 548.1 0.0 1.3e-148 495.7 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase FTR1 PF03239.9 KND94155.1 - 1.1e-80 270.8 9.1 1.3e-80 270.6 6.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 KND94155.1 - 0.011 15.7 0.3 0.011 15.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2721 PF11026.3 KND94155.1 - 0.037 13.6 4.1 7.4 6.2 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) DUF4293 PF14126.1 KND94155.1 - 0.41 10.5 4.1 1.5 8.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) DUF3464 PF11947.3 KND94155.1 - 1.6 8.1 6.5 1.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Cu-oxidase_3 PF07732.10 KND94156.1 - 4.6e-45 152.1 6.3 1.9e-42 143.6 0.6 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 KND94156.1 - 1.3e-42 145.3 1.2 1.8e-37 128.6 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND94156.1 - 1.5e-42 144.3 5.7 2.7e-38 130.6 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KND94156.1 - 0.0002 21.2 0.0 2.1 8.3 0.0 3.7 2 1 0 2 2 2 2 Cupredoxin-like domain C1q PF00386.16 KND94156.1 - 0.13 12.3 0.0 8 6.4 0.0 2.6 2 0 0 2 2 2 0 C1q domain OMPdecase PF00215.19 KND94157.1 - 1.6e-99 331.9 0.0 2.3e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.13 KND94157.1 - 2.9e-11 42.7 0.0 4.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94157.1 - 2.6e-07 30.4 10.8 5.5e-07 29.3 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 KND94158.1 - 0.0025 17.4 1.2 0.0025 17.4 0.8 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KND94158.1 - 0.017 15.1 4.5 0.3 11.1 0.4 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Succ_CoA_lig PF13607.1 KND94158.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Dynactin PF12455.3 KND94159.1 - 7.1e-89 297.3 3.9 7.1e-89 297.3 2.7 2.9 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 KND94159.1 - 5.5e-21 74.0 0.4 1e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Reo_sigmaC PF04582.7 KND94159.1 - 1.1 8.3 19.3 0.71 8.9 0.4 4.7 2 2 2 4 4 4 0 Reovirus sigma C capsid protein HMG_box PF00505.14 KND94160.1 - 2.6e-22 78.8 3.8 5.3e-22 77.8 2.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND94160.1 - 9.3e-07 29.1 1.9 9.3e-07 29.1 1.3 1.8 2 0 0 2 2 2 1 HMG-box domain TIP49 PF06068.8 KND94161.1 - 1.3e-187 623.3 0.2 1.6e-187 623.1 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KND94161.1 - 1.9e-11 44.2 1.1 4.5e-07 30.1 0.1 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND94161.1 - 2.2e-09 36.7 0.1 3.6e-06 26.1 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KND94161.1 - 2.9e-05 23.7 0.2 9.4e-05 22.0 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KND94161.1 - 0.00016 21.8 0.2 0.81 9.8 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KND94161.1 - 0.00035 20.6 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KND94161.1 - 0.0005 20.0 0.1 0.0012 18.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND94161.1 - 0.0031 16.9 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND94161.1 - 0.0043 16.7 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KND94161.1 - 0.0045 16.1 0.2 0.013 14.5 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KND94161.1 - 0.011 15.2 0.2 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 KND94161.1 - 0.019 13.9 0.1 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 KND94161.1 - 0.021 13.7 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 KND94161.1 - 0.022 14.2 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KND94161.1 - 0.023 14.9 0.1 0.05 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KND94161.1 - 0.026 13.6 0.1 0.75 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KND94161.1 - 0.085 13.6 0.1 0.2 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 KND94161.1 - 0.11 12.0 0.1 0.28 10.6 0.1 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF2204 PF09970.4 KND94162.1 - 0.00092 18.7 0.1 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) TraD PF06412.6 KND94162.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Conjugal transfer protein TraD DUF4131 PF13567.1 KND94164.1 - 0.08 12.3 6.8 0.085 12.2 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Coa1 PF08695.5 KND94165.1 - 6.1e-39 132.1 0.0 8.2e-39 131.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CUE PF02845.11 KND94166.1 - 2.2e-12 46.2 0.0 3.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.2 KND94167.1 - 4.9e-39 132.5 4.8 8.9e-14 51.5 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) SPX PF03105.14 KND94167.1 - 5.7e-31 108.3 13.2 7.5e-18 65.2 3.6 2.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KND94167.1 - 5.9e-28 96.7 9.1 2.9e-10 40.3 0.0 6.1 2 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 KND94167.1 - 5.4e-24 82.7 13.8 2.6e-06 26.9 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KND94167.1 - 6.6e-20 70.6 12.1 3.6e-06 27.0 0.0 7.6 2 1 6 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94167.1 - 1.8e-15 55.5 7.8 0.00014 21.7 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat GDPD PF03009.12 KND94167.1 - 4.3e-09 36.2 0.0 7e-08 32.2 0.0 2.7 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Orn_Arg_deC_N PF02784.11 KND94167.1 - 0.17 11.0 0.1 0.34 10.0 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain EzrA PF06160.7 KND94167.1 - 0.32 9.1 5.4 0.57 8.2 3.7 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA UBA_e1_thiolCys PF10585.4 KND94168.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Rrn6 PF10214.4 KND94169.1 - 1.4e-61 208.6 7.3 1.2e-53 182.3 0.1 2.8 2 1 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 KND94170.1 - 1.5e-22 79.3 0.0 3.6e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 S6PP PF05116.8 KND94170.1 - 0.013 14.8 0.2 0.027 13.7 0.1 1.6 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase UDPG_MGDP_dh_N PF03721.9 KND94170.1 - 0.029 13.7 0.3 0.051 12.9 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VRP1 PF03538.9 KND94170.1 - 0.042 12.8 1.3 0.093 11.7 0.6 1.7 1 1 1 2 2 2 0 Salmonella virulence plasmid 28.1kDa A protein SRRM_C PF15230.1 KND94170.1 - 0.058 13.4 0.7 0.058 13.4 0.5 2.0 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Atg14 PF10186.4 KND94170.1 - 0.12 11.2 6.6 0.18 10.7 4.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_23 PF13476.1 KND94170.1 - 0.51 10.6 4.8 0.15 12.3 1.3 1.6 2 0 0 2 2 2 0 AAA domain Hom_end_hint PF05203.11 KND94170.1 - 0.85 9.3 3.7 1.3 8.6 2.6 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint APG6 PF04111.7 KND94170.1 - 3.9 6.4 13.0 2.5 7.0 0.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Ribosomal_L3 PF00297.17 KND94171.1 - 2.4e-31 109.1 1.6 9e-31 107.2 1.1 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 GN3L_Grn1 PF08701.6 KND94171.1 - 0.086 12.7 5.0 0.16 11.8 3.5 1.3 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase PITH PF06201.8 KND94172.1 - 4.2e-43 146.7 0.0 5e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain MOZART1 PF12554.3 KND94173.1 - 7.2e-25 86.1 0.7 8.5e-25 85.9 0.5 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated WXG100 PF06013.7 KND94173.1 - 0.11 12.5 0.5 0.99 9.4 0.1 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG zinc_ribbon_6 PF14599.1 KND94174.1 - 6.9e-26 89.8 0.2 6.9e-26 89.8 0.1 4.0 5 1 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 KND94174.1 - 1.1e-16 60.6 19.9 1.1e-16 60.6 13.8 4.4 3 1 0 3 3 3 2 CHY zinc finger zf-RING_2 PF13639.1 KND94174.1 - 1.5e-08 34.2 9.7 1.5e-08 34.2 6.7 4.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND94174.1 - 1.1e-07 31.7 8.6 1.1e-07 31.7 5.9 5.2 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND94174.1 - 2.6e-07 30.1 8.2 2.6e-07 30.1 5.7 5.5 3 2 3 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND94174.1 - 8.9e-06 25.3 8.4 8.9e-06 25.3 5.8 6.2 2 1 4 6 6 6 1 zinc-RING finger domain TIP49 PF06068.8 KND94177.1 - 6e-173 575.1 2.2 7.1e-173 574.8 1.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KND94177.1 - 1e-07 32.1 0.5 0.00012 22.3 0.0 2.8 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND94177.1 - 2e-07 30.3 0.7 0.0007 18.7 0.0 2.6 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KND94177.1 - 3.8e-06 25.9 0.3 6.5e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KND94177.1 - 0.0014 18.7 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KND94177.1 - 0.0048 16.0 0.5 0.12 11.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KND94177.1 - 0.015 15.3 0.0 0.14 12.1 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KND94177.1 - 0.074 12.7 0.2 16 5.2 0.0 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Glyco_hydro_63 PF03200.11 KND94178.1 - 0.0016 16.4 1.9 0.003 15.4 1.3 1.4 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DUF2594 PF10769.4 KND94178.1 - 0.0097 15.9 0.1 0.039 14.0 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2594) Gp_dh_C PF02800.15 KND94180.1 - 5.1e-73 243.7 0.1 7.3e-73 243.1 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KND94180.1 - 9.4e-60 200.9 0.2 1.5e-59 200.3 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KND94180.1 - 0.0044 16.9 0.9 0.013 15.4 0.1 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 KND94180.1 - 0.036 13.5 0.2 0.18 11.3 0.0 2.0 1 1 1 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KND94180.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GYF PF02213.11 KND94181.1 - 1.2e-09 37.6 0.8 2.3e-09 36.6 0.5 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 KND94182.1 - 2.3e-63 212.5 0.0 3e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Ribosomal_L3 PF00297.17 KND94186.1 - 4.2e-118 393.5 9.1 5e-118 393.2 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 SPO22 PF08631.5 KND94187.1 - 8.7e-55 185.7 0.0 1.8e-54 184.7 0.0 1.5 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KND94187.1 - 0.00024 20.9 2.8 0.31 11.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Nterm_IS4 PF13006.2 KND94187.1 - 0.011 15.7 1.2 1 9.3 0.0 3.9 4 0 0 4 4 4 0 Insertion element 4 transposase N-terminal Malate_synthase PF01274.17 KND94187.1 - 0.019 13.0 0.0 0.34 8.8 0.0 2.1 2 0 0 2 2 2 0 Malate synthase Zn_clus PF00172.13 KND94188.1 - 0.56 10.1 7.0 0.064 13.1 1.1 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ald_Xan_dh_C2 PF02738.13 KND94189.1 - 2.1e-192 640.2 0.3 3.2e-192 639.7 0.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Aminotran_1_2 PF00155.16 KND94189.1 - 1.1e-63 215.4 0.0 1.9e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_5 PF00941.16 KND94189.1 - 7.5e-46 155.6 0.0 1.5e-45 154.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Pkinase PF00069.20 KND94189.1 - 4.5e-35 121.0 0.0 7.4e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ald_Xan_dh_C PF01315.17 KND94189.1 - 2.2e-32 111.4 0.3 5.2e-32 110.2 0.2 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KND94189.1 - 4.8e-29 100.0 0.1 1.1e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 KND94189.1 - 5e-29 100.2 0.7 1.4e-27 95.6 0.1 3.1 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Pkinase_Tyr PF07714.12 KND94189.1 - 6.7e-21 74.5 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94189.1 - 1.3e-07 30.9 0.0 2.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Fer2 PF00111.22 KND94189.1 - 4.6e-07 29.4 2.1 4.8e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Beta_elim_lyase PF01212.16 KND94189.1 - 7.4e-05 22.0 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KND94189.1 - 0.0001 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Kdo PF06293.9 KND94189.1 - 0.0075 15.3 0.0 0.021 13.8 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cys_Met_Meta_PP PF01053.15 KND94189.1 - 0.015 13.5 0.0 0.028 12.7 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme JmjC PF02373.17 KND94190.1 - 3.4e-37 127.1 0.3 9.9e-37 125.6 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KND94190.1 - 3.9e-20 71.8 6.3 7.3e-20 71.0 4.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KND94190.1 - 1.2e-19 70.2 5.4 1.2e-19 70.2 3.7 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 KND94190.1 - 2.3e-13 49.4 1.6 5.4e-13 48.2 1.1 1.7 1 0 0 1 1 1 1 jmjN domain Abhydrolase_3 PF07859.8 KND94191.1 - 4.5e-35 121.1 0.0 1.4e-23 83.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND94191.1 - 0.007 16.1 0.0 0.037 13.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KND94191.1 - 0.047 12.3 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Ufd2P_core PF10408.4 KND94194.1 - 1.1e-181 605.2 11.4 1.7e-181 604.6 7.9 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KND94194.1 - 1.3e-25 89.1 7.4 2e-25 88.5 0.6 3.4 3 0 0 3 3 3 1 U-box domain zf-TRAF PF02176.13 KND94194.1 - 2.6e-09 37.3 26.7 7e-07 29.5 1.4 3.6 2 1 1 3 3 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KND94194.1 - 1.3e-08 34.7 5.8 1.3e-08 34.7 4.0 3.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND94194.1 - 4.9e-08 32.5 4.9 4.9e-08 32.5 3.4 3.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND94194.1 - 1.9e-07 30.8 6.6 1.9e-07 30.8 4.6 3.0 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KND94194.1 - 5.5e-07 29.3 6.0 5.5e-07 29.3 4.2 3.2 4 0 0 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND94194.1 - 8.5e-06 25.3 1.8 8.5e-06 25.3 1.3 3.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND94194.1 - 9.1e-06 25.3 2.9 9.1e-06 25.3 2.0 3.1 2 1 1 3 3 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KND94194.1 - 0.0014 18.3 6.2 0.0043 16.7 3.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger TFIIA PF03153.8 KND94194.1 - 0.078 12.8 6.2 0.18 11.6 4.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC-167 PF15188.1 KND94194.1 - 1 9.3 8.9 0.11 12.5 1.1 2.9 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 TMF_TATA_bd PF12325.3 KND94194.1 - 1.4 8.6 13.2 3.1 7.5 0.2 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2361 PF10153.4 KND94194.1 - 1.9 8.6 9.2 0.6 10.3 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) A_deaminase PF00962.17 KND94195.1 - 5.7e-25 87.9 0.0 1.8e-22 79.7 0.0 2.0 1 1 1 2 2 2 2 Adenosine/AMP deaminase F_bP_aldolase PF01116.15 KND94195.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Fungal_trans PF04082.13 KND94196.1 - 6.7e-27 93.9 0.8 1e-26 93.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94196.1 - 5.8e-08 32.5 13.7 1.1e-07 31.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KND94197.1 - 5.4e-30 104.3 0.0 1.1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_2 PF00328.17 KND94197.1 - 6.4e-07 29.0 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_1 PF00170.16 KND94198.1 - 1.1e-09 38.1 11.2 2.8e-09 36.7 7.8 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND94198.1 - 0.00013 21.7 10.0 0.00034 20.3 7.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper SNAP PF14938.1 KND94199.1 - 5.6e-93 311.1 12.5 6.3e-93 310.9 8.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KND94199.1 - 2.9e-05 23.9 10.6 0.0024 17.7 1.5 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND94199.1 - 9.1e-05 22.6 6.0 4.4 7.9 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND94199.1 - 0.00072 19.2 12.1 2.1 8.4 0.1 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND94199.1 - 0.002 18.5 10.7 0.73 10.6 0.1 4.8 2 1 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND94199.1 - 0.0058 16.3 4.4 1.1 9.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND94199.1 - 0.017 14.7 13.5 0.12 12.0 1.0 3.7 1 1 3 4 4 4 0 TPR repeat TPR_16 PF13432.1 KND94199.1 - 0.023 15.3 10.1 0.13 12.9 0.1 3.6 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF2521 PF10730.4 KND94199.1 - 0.04 13.7 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) TPR_19 PF14559.1 KND94199.1 - 0.078 13.3 0.3 0.078 13.3 0.2 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND94199.1 - 0.079 12.8 5.0 2.8 7.9 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND94199.1 - 0.26 10.9 8.7 11 5.8 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KND94199.1 - 3.8 7.4 6.5 9.4 6.1 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.10 KND94200.1 - 5.4e-06 26.1 0.7 5.1e-05 22.9 0.2 2.1 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Caps_synth_GfcC PF06251.6 KND94200.1 - 0.066 12.3 0.1 0.092 11.8 0.1 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC tRNA-synt_1d PF00750.14 KND94201.1 - 1.1e-75 254.6 5.5 3.4e-75 253.0 3.8 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KND94201.1 - 2.7e-24 85.3 0.0 5.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KND94201.1 - 0.00019 21.8 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain EAP30 PF04157.11 KND94201.1 - 0.12 11.5 0.0 0.35 9.9 0.0 1.8 1 0 0 1 1 1 0 EAP30/Vps36 family AMP-binding PF00501.23 KND94202.1 - 1.1e-24 86.6 0.1 1.4e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme L51_S25_CI-B8 PF05047.11 KND94203.1 - 3.8e-16 58.5 0.1 6.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF4602 PF15375.1 KND94203.1 - 0.041 13.9 5.2 0.056 13.5 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) GDYXXLXY PF14345.1 KND94203.1 - 0.095 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 GDYXXLXY protein DOR PF14839.1 KND94203.1 - 0.25 11.0 6.2 0.34 10.6 4.3 1.1 1 0 0 1 1 1 0 DOR family PPI_Ypi1 PF07491.6 KND94205.1 - 3e-25 87.5 1.4 9.1e-25 86.0 1.0 1.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor Apt1 PF10351.4 KND94205.1 - 1.8 7.3 4.2 2.2 7.0 2.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TP53IP5 PF15331.1 KND94205.1 - 4.5 7.1 8.7 0.2 11.5 1.0 1.9 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 RAP1 PF07218.6 KND94205.1 - 7.5 4.5 5.6 8.4 4.3 3.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MMR_HSR1 PF01926.18 KND94206.1 - 9.1e-06 25.6 0.0 4.6e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase HECT PF00632.20 KND94207.1 - 3.7e-75 253.0 0.0 5.7e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 KND94207.1 - 0.068 12.9 1.0 0.14 11.9 0.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3712 PF12505.3 KND94208.1 - 2.9e-06 27.3 0.0 6.3e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) Na_Ca_ex PF01699.19 KND94209.1 - 3.9e-32 110.7 33.2 9e-19 67.4 7.1 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KND94209.1 - 1.9e-12 47.4 12.3 1.9e-12 47.4 8.5 3.8 2 0 0 2 2 2 1 Domain of unknown function (DUF307) Curto_V2 PF07325.6 KND94209.1 - 0.21 11.2 1.2 0.39 10.3 0.9 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF1989 PF09347.5 KND94211.1 - 3.4e-51 172.9 0.0 4.3e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.24 KND94212.1 - 9.7e-44 148.7 0.0 1.6e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND94212.1 - 1e-07 31.7 0.0 2.7e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND94212.1 - 4.9e-07 29.8 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KND94212.1 - 2.5e-06 27.5 0.0 5.2e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND94212.1 - 1.2e-05 25.4 0.1 0.00061 19.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND94212.1 - 0.00011 21.8 0.1 0.00025 20.7 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KND94212.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KND94212.1 - 0.00013 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KND94212.1 - 0.00027 21.7 0.0 0.00071 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KND94212.1 - 0.0015 17.3 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KND94212.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND94212.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND94212.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KND94212.1 - 0.0034 16.8 0.1 0.013 14.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KND94212.1 - 0.0047 16.8 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND94212.1 - 0.0057 16.9 0.1 0.03 14.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain KaiC PF06745.8 KND94212.1 - 0.0057 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 KND94212.1 - 0.0062 15.7 0.1 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KND94212.1 - 0.007 15.9 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KND94212.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KND94212.1 - 0.014 14.5 0.0 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KND94212.1 - 0.018 14.6 0.1 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.4 KND94212.1 - 0.02 14.7 0.2 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Sigma54_activat PF00158.21 KND94212.1 - 0.021 14.2 0.0 0.097 12.1 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KND94212.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KND94212.1 - 0.046 13.3 0.0 0.28 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KND94212.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Histone PF00125.19 KND94212.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Parvo_NS1 PF01057.12 KND94212.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KND94212.1 - 0.078 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Tcp11 PF05794.8 KND94213.1 - 3.4e-44 151.2 1.9 5.8e-44 150.5 0.0 2.0 2 0 0 2 2 2 1 T-complex protein 11 Y_phosphatase PF00102.22 KND94214.1 - 7.3e-60 202.2 0.0 3.8e-50 170.4 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 KND94214.1 - 1.4e-10 41.4 0.0 3.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KND94214.1 - 0.026 14.7 0.1 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 KND94214.1 - 0.076 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Peptidase_M1 PF01433.15 KND94215.1 - 1e-133 446.2 0.3 1.3e-133 445.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KND94215.1 - 5.5e-70 236.1 0.0 8e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KND94215.1 - 1.5e-20 73.5 0.6 1.5e-20 73.5 0.4 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KND94215.1 - 0.018 14.8 0.0 0.092 12.5 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function DUF45 zf-FCS PF06467.9 KND94216.1 - 0.034 13.7 1.4 0.06 12.9 0.3 1.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HATPase_c PF02518.21 KND94216.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1467 PF07330.7 KND94217.1 - 0.32 10.7 4.1 0.2 11.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) COesterase PF00135.23 KND94218.1 - 1.7e-89 300.9 0.0 2.4e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KND94218.1 - 5.6e-06 26.0 0.3 3e-05 23.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DEC-1_N PF04625.8 KND94218.1 - 0.12 11.0 9.5 0.08 11.5 5.3 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PLRV_ORF5 PF01690.12 KND94218.1 - 1.5 7.8 11.5 2.2 7.3 8.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2638 PF10937.3 KND94219.1 - 2.5e-34 118.6 1.5 4.4e-34 117.8 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) AA_permease PF00324.16 KND94221.1 - 9.1e-142 472.7 48.4 2.5e-134 448.2 23.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KND94221.1 - 8.2e-33 113.5 32.6 8.2e-33 113.5 22.6 2.9 1 1 1 3 3 3 3 Amino acid permease MFS_1 PF07690.11 KND94222.1 - 1.8e-19 69.6 25.8 3.1e-19 68.9 17.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KND94222.1 - 3.8e-09 36.2 5.9 3.8e-09 36.2 4.1 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Aminotran_1_2 PF00155.16 KND94223.1 - 7e-80 268.6 0.0 8.7e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GHMP_kinases_N PF00288.21 KND94224.1 - 3.4e-19 68.6 0.0 1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND94224.1 - 4.1e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KND94224.1 - 0.0057 15.9 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF1992 PF09350.5 KND94225.1 - 4.5e-22 77.6 0.3 1.1e-21 76.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Sugar_tr PF00083.19 KND94226.1 - 2.7e-82 276.7 18.6 3.2e-82 276.5 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND94226.1 - 2.6e-13 49.4 30.0 1.9e-09 36.7 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND94226.1 - 3e-07 29.1 28.3 6.1e-05 21.5 0.8 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein DUF4131 PF13567.1 KND94226.1 - 2.6 7.4 18.1 2.4 7.5 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 KND94228.1 - 3.2e-27 95.1 39.6 3.3e-25 88.5 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94228.1 - 7.4e-18 64.3 29.4 1.1e-17 63.7 20.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 KND94228.1 - 0.039 13.5 0.8 0.075 12.6 0.6 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase TPR_1 PF00515.23 KND94230.1 - 1.1e-46 154.6 32.1 8.9e-08 31.4 0.1 10.4 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KND94230.1 - 7.2e-41 134.8 22.4 6.1e-06 25.7 0.0 10.1 11 0 0 11 11 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 KND94230.1 - 1e-39 134.0 28.0 1.4e-11 43.8 1.0 6.5 2 2 5 8 8 8 8 TPR repeat TPR_16 PF13432.1 KND94230.1 - 2e-29 101.6 17.8 4.8e-08 33.4 0.5 6.6 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 KND94230.1 - 8.2e-29 97.1 24.7 3.1e-05 23.4 0.0 10.2 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.1 KND94230.1 - 2.3e-26 89.7 21.7 0.0014 18.6 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KND94230.1 - 5.3e-25 87.1 24.9 1.5e-06 28.0 0.2 7.2 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 KND94230.1 - 1e-22 78.5 13.9 0.00031 21.1 0.0 9.1 3 2 6 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 KND94230.1 - 1.4e-19 70.1 22.2 2.1e-05 24.7 0.2 6.9 3 3 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 KND94230.1 - 2.3e-15 55.8 19.3 0.011 16.1 0.0 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 KND94230.1 - 3.2e-14 51.5 12.2 0.046 13.5 0.0 9.2 9 1 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 KND94230.1 - 1e-10 41.5 13.2 1.9e-07 31.0 0.9 4.8 4 1 0 5 5 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KND94230.1 - 4.8e-09 35.9 12.6 0.035 13.9 0.0 5.9 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.1 KND94230.1 - 3.7e-08 32.7 8.6 0.068 12.2 0.8 4.5 2 2 3 5 5 5 3 Tetratricopeptide repeat DUF2225 PF09986.4 KND94230.1 - 0.0076 15.7 3.3 0.058 12.8 0.2 2.7 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.1 KND94230.1 - 0.036 13.9 0.4 14 5.7 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 KND94230.1 - 0.075 13.1 0.2 12 6.1 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KND94230.1 - 0.26 11.2 15.4 0.056 13.3 0.5 4.2 5 1 0 5 5 4 0 Tetratricopeptide repeat Adaptin_N PF01602.15 KND94230.1 - 0.82 7.9 0.0 1.2 7.3 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region TPR_10 PF13374.1 KND94230.1 - 5.3 7.1 20.2 3.7 7.6 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat NuiA PF07924.6 KND94231.1 - 0.074 12.9 0.2 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Reprolysin_5 PF13688.1 KND94232.1 - 3.3e-59 200.1 2.6 1e-58 198.5 1.8 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KND94232.1 - 2.4e-47 161.1 0.3 4.1e-47 160.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KND94232.1 - 7.7e-44 149.8 0.8 1.8e-43 148.6 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KND94232.1 - 2.3e-18 66.9 0.2 7.4e-18 65.2 0.2 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KND94232.1 - 7.5e-18 64.5 29.9 7.5e-18 64.5 20.7 4.8 3 2 1 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 KND94232.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide WD40 PF00400.27 KND94233.1 - 2.1e-12 46.4 10.5 3e-05 23.7 0.0 7.4 8 0 0 8 8 8 2 WD domain, G-beta repeat IKI3 PF04762.7 KND94233.1 - 0.035 11.9 0.0 0.16 9.7 0.0 1.9 2 0 0 2 2 2 0 IKI3 family eIF2A PF08662.6 KND94233.1 - 0.059 13.0 0.2 15 5.1 0.0 3.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Med3 PF11593.3 KND94233.1 - 6.9 5.7 13.4 0.92 8.6 6.2 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal PRP3 PF08572.5 KND94234.1 - 1.5 8.1 8.3 0.26 10.6 3.3 1.5 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) DUF1751 PF08551.5 KND94236.1 - 3.2e-25 88.3 5.1 6.3e-25 87.3 3.6 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KND94236.1 - 0.24 11.3 10.7 0.67 9.9 7.4 1.7 1 0 0 1 1 1 0 Rhomboid family Chorismate_bind PF00425.13 KND94237.1 - 3.5e-88 295.2 0.0 5.7e-87 291.2 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KND94237.1 - 5.2e-27 94.5 0.0 4.6e-24 85.0 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Hexapep PF00132.19 KND94240.1 - 2.9e-09 35.9 0.1 2.8e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KND94240.1 - 0.0027 17.7 0.0 0.0074 16.3 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KND94240.1 - 0.0041 16.4 0.0 0.0097 15.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KND94240.1 - 0.051 13.1 5.6 0.91 9.1 0.0 3.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase ATG27 PF09451.5 KND94241.1 - 1.2e-73 247.6 8.5 3.2e-72 242.9 5.9 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KND94241.1 - 2.5e-05 24.0 0.0 0.061 13.0 0.0 2.9 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Spt20 PF12090.3 KND94242.1 - 8.1e-43 145.8 0.0 8.1e-43 145.8 0.0 4.7 4 1 1 5 5 5 1 Spt20 family RdRP PF05183.7 KND94243.1 - 2.8e-165 551.3 0.0 3.6e-165 550.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Abhydrolase_6 PF12697.2 KND94244.1 - 2.8e-27 96.0 4.4 2.8e-27 96.0 3.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND94244.1 - 3.3e-10 39.9 0.1 2.6e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KND94244.1 - 3.5e-08 32.2 0.0 5.3e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 KND94244.1 - 1e-07 31.8 0.2 5e-07 29.5 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KND94244.1 - 0.0048 16.3 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-C2H2 PF00096.21 KND94245.1 - 0.00091 19.4 25.0 0.0078 16.5 1.0 3.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND94245.1 - 0.0076 16.5 19.4 0.16 12.4 0.5 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger DUF3505 PF12013.3 KND94245.1 - 0.022 14.9 2.4 0.047 13.9 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-H2C2_2 PF13465.1 KND94245.1 - 0.024 14.8 1.6 0.024 14.8 1.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain Ogr_Delta PF04606.7 KND94245.1 - 0.86 9.3 5.0 0.15 11.7 0.5 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Grp1_Fun34_YaaH PF01184.14 KND94246.1 - 7.7e-14 51.4 22.8 6.3e-13 48.5 15.8 1.9 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Amidohydro_2 PF04909.9 KND94247.1 - 8.6e-24 84.5 0.2 1.2e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Mre11_DNA_bind PF04152.9 KND94249.1 - 2.1e-55 187.2 0.6 2.1e-55 187.2 0.4 2.0 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KND94249.1 - 5.4e-25 87.9 2.0 7.9e-25 87.4 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND94249.1 - 7.2e-07 29.1 0.0 1.8e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 KND94250.1 - 2.4e-14 52.8 27.6 2.4e-14 52.8 19.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KND94250.1 - 2.6e-05 23.5 5.9 2.6e-05 23.5 4.1 2.7 2 1 0 2 2 2 1 Nodulin-like ATP1G1_PLM_MAT8 PF02038.11 KND94250.1 - 7.8 5.5 11.7 14 4.7 0.1 3.6 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family NACHT PF05729.7 KND94251.1 - 2.7e-05 23.8 0.1 0.0001 22.0 0.1 1.9 1 1 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.13 KND94251.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KND94251.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND94251.1 - 0.034 14.1 0.0 0.097 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain F-box PF00646.28 KND94252.1 - 0.00022 20.8 1.7 0.00064 19.2 0.1 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KND94252.1 - 0.076 12.7 3.4 0.37 10.5 2.4 2.2 1 1 0 1 1 1 0 F-box-like Inositol_P PF00459.20 KND94253.1 - 2.8e-36 125.2 0.0 6e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Epimerase PF01370.16 KND94254.1 - 4.5e-20 72.1 0.0 1e-19 70.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KND94254.1 - 1.4e-08 34.0 0.0 2.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KND94254.1 - 1.4e-07 30.7 1.8 1.7e-05 23.8 0.1 2.8 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KND94254.1 - 5.6e-07 28.7 1.4 1e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KND94254.1 - 0.00038 19.2 0.0 0.0012 17.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KND94254.1 - 0.82 9.5 8.2 0.52 10.2 0.3 3.2 3 0 0 3 3 3 0 short chain dehydrogenase Band_7 PF01145.20 KND94255.1 - 3.4e-13 49.8 0.0 3.4e-13 49.8 0.0 3.3 2 2 1 3 3 3 1 SPFH domain / Band 7 family FUSC PF04632.7 KND94255.1 - 1.7 6.9 20.6 2.5 6.4 14.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRO1 PF03097.13 KND94256.1 - 1e-106 356.9 0.0 1.7e-106 356.1 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KND94256.1 - 1.5e-56 191.5 1.2 2.3e-48 164.6 0.3 2.6 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV K-box PF01486.12 KND94256.1 - 0.2 11.4 4.9 0.29 10.9 0.0 3.2 3 0 0 3 3 3 0 K-box region LSM PF01423.17 KND94257.1 - 1.5e-11 43.6 0.0 2.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain Ras PF00071.17 KND94259.1 - 2.6e-65 218.7 0.4 3e-65 218.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND94259.1 - 2.1e-21 76.5 0.0 3.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND94259.1 - 4e-16 58.7 0.1 4.7e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND94259.1 - 2.6e-05 23.5 0.1 3.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND94259.1 - 4.5e-05 22.9 0.1 9.4e-05 21.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND94259.1 - 7.1e-05 22.7 0.1 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KND94259.1 - 0.0006 20.0 0.0 0.13 12.4 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KND94259.1 - 0.00062 19.0 0.0 0.0009 18.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KND94259.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KND94259.1 - 0.0031 16.8 0.0 0.023 13.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KND94259.1 - 0.0069 15.5 0.2 0.025 13.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KND94259.1 - 0.0078 16.1 0.2 0.022 14.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND94259.1 - 0.016 15.2 0.1 0.065 13.2 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KND94259.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KND94259.1 - 0.052 12.5 0.0 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 KND94259.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KND94259.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter RNase_PH PF01138.16 KND94262.1 - 1.8e-14 54.1 0.0 2.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KND94262.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATE_C PF04377.10 KND94263.1 - 1.9e-41 141.1 0.1 3.1e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KND94263.1 - 5.9e-16 58.0 0.7 1.2e-15 57.0 0.5 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KND94263.1 - 0.031 14.2 0.4 0.097 12.6 0.1 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 KND94264.1 - 5.5e-19 68.1 0.3 6.4e-19 67.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 KND94265.1 - 4.6e-64 214.5 0.0 1.5e-45 154.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND94265.1 - 7.6e-11 41.8 0.1 4.9e-06 26.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KND94265.1 - 9.5e-11 42.0 1.6 9.6e-05 22.4 0.0 3.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 KND94265.1 - 2.4e-09 38.0 0.0 0.00035 21.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KND94265.1 - 3.2e-09 36.7 0.0 0.0014 18.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KND94265.1 - 1.7e-08 34.6 0.0 0.002 18.2 0.0 3.9 3 1 0 3 3 2 2 AAA domain AAA_2 PF07724.9 KND94265.1 - 2.1e-08 34.2 0.0 1.1e-06 28.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KND94265.1 - 4.8e-07 29.0 0.0 0.00041 19.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KND94265.1 - 5.1e-07 29.3 0.0 0.0059 16.3 0.0 3.4 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KND94265.1 - 3.8e-06 26.8 0.0 0.00022 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KND94265.1 - 1.4e-05 24.2 0.2 0.0006 18.9 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin DUF815 PF05673.8 KND94265.1 - 2e-05 23.6 0.0 0.097 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 KND94265.1 - 2.7e-05 24.4 0.1 0.36 11.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KND94265.1 - 4.4e-05 23.5 0.1 0.05 13.6 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 KND94265.1 - 5.3e-05 22.7 5.1 0.44 9.9 0.0 4.8 3 2 2 5 5 5 2 AAA domain TIP49 PF06068.8 KND94265.1 - 7.9e-05 21.5 0.0 0.063 11.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KND94265.1 - 0.00014 21.3 0.1 0.026 13.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 KND94265.1 - 0.00019 21.4 0.1 0.52 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KND94265.1 - 0.00026 20.4 0.0 0.17 11.3 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KND94265.1 - 0.00029 20.9 0.0 0.064 13.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 KND94265.1 - 0.0012 18.5 0.3 1.1 8.9 0.0 3.3 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.22 KND94265.1 - 0.0013 19.0 0.0 0.32 11.2 0.0 2.9 2 1 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.16 KND94265.1 - 0.0038 16.4 0.4 0.13 11.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KND94265.1 - 0.0095 14.6 0.0 1 7.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ResIII PF04851.10 KND94265.1 - 0.01 15.6 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KND94265.1 - 0.013 15.0 0.1 0.66 9.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KND94265.1 - 0.034 13.7 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KND94265.1 - 0.035 13.6 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KND94265.1 - 0.053 13.0 0.2 0.28 10.6 0.0 2.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KND94265.1 - 0.077 12.6 0.0 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 NTPase IPT PF01745.11 KND94265.1 - 0.078 12.1 0.0 8.3 5.5 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase AAA_3 PF07726.6 KND94265.1 - 0.12 11.9 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 KND94265.1 - 0.13 12.1 0.3 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase KaiC PF06745.8 KND94265.1 - 0.19 10.8 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 KND94265.1 - 0.23 10.2 0.0 0.99 8.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Cytochrom_C PF00034.16 KND94266.1 - 2.1e-11 44.4 0.0 3.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KND94266.1 - 1.2e-08 34.9 3.5 4.9e-08 33.0 2.4 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KND94266.1 - 0.00088 18.7 0.0 0.009 15.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Porphobil_deam PF01379.15 KND94267.1 - 4.4e-06 25.7 0.0 4.5e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain CN_hydrolase PF00795.17 KND94268.1 - 5.4e-22 78.0 0.0 8.2e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CPSF73-100_C PF11718.3 KND94269.1 - 9.9e-77 257.1 0.0 1e-73 247.3 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KND94269.1 - 8.6e-32 109.7 0.0 1.9e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KND94269.1 - 3.4e-14 52.9 0.7 7.5e-14 51.8 0.5 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND94269.1 - 3.5e-12 46.2 0.6 5.9e-12 45.5 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KND94269.1 - 1.4e-06 27.9 0.3 2.7e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KND94269.1 - 3.4e-06 26.8 0.2 8.4e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 KND94270.1 - 3.2e-10 39.7 4.6 1.3e-09 37.7 2.3 2.5 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family LRR_6 PF13516.1 KND94271.1 - 0.00014 21.6 0.1 1.5 9.1 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 KND94271.1 - 0.00033 20.3 0.2 51 4.7 0.0 5.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KND94271.1 - 0.0013 18.5 0.3 55 4.3 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 KND94271.1 - 0.0025 17.3 0.0 4.3 7.0 0.0 4.2 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND94271.1 - 0.01 15.5 1.4 2.9 7.7 0.0 4.3 2 2 3 5 5 5 0 Leucine rich repeat V_ATPase_I PF01496.14 KND94272.1 - 9.2e-298 989.3 0.3 1e-297 989.1 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF869 PF05911.6 KND94272.1 - 0.015 13.5 1.5 0.84 7.7 0.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 KND94272.1 - 0.044 13.2 11.0 0.32 10.3 0.6 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF3552 PF12072.3 KND94272.1 - 0.079 12.1 3.3 5.6 6.1 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) AAA_13 PF13166.1 KND94272.1 - 0.1 11.0 3.0 1.7 6.9 0.4 2.1 2 0 0 2 2 2 0 AAA domain TBPIP PF07106.8 KND94272.1 - 0.11 12.0 4.8 0.52 9.8 0.2 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 KND94272.1 - 0.13 12.6 3.9 1.9 8.9 0.5 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ERM PF00769.14 KND94272.1 - 0.19 11.2 3.2 0.33 10.4 0.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 KND94272.1 - 0.22 11.2 5.0 6.3 6.5 0.1 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF1515 PF07439.6 KND94272.1 - 0.22 11.3 1.3 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Serine_rich PF08824.5 KND94272.1 - 0.45 10.2 4.6 0.31 10.7 0.7 2.3 2 1 0 2 2 2 0 Serine rich protein interaction domain CCDC-167 PF15188.1 KND94272.1 - 0.91 9.5 7.0 5.3 7.0 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.15 KND94272.1 - 0.91 9.3 3.9 17 5.1 0.1 2.9 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 KND94272.1 - 1.6 8.5 7.2 0.93 9.3 0.8 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 KND94272.1 - 3.4 7.6 10.4 8.1 6.3 1.8 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Syntaxin PF00804.20 KND94272.1 - 4.3 7.5 6.5 1.7 8.8 0.4 2.6 2 1 0 2 2 2 0 Syntaxin Uds1 PF15456.1 KND94272.1 - 6.6 6.7 8.3 6.2 6.8 1.8 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DivIC PF04977.10 KND94272.1 - 8.8 5.8 9.8 0.88 9.0 1.0 3.2 2 1 0 3 3 3 0 Septum formation initiator Prenyltransf PF01255.14 KND94273.1 - 2.1e-85 285.3 0.0 3.1e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.19 KND94273.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PHD PF00628.24 KND94274.1 - 4.4e-10 39.0 7.7 7.1e-10 38.4 5.3 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KND94274.1 - 2.6e-06 27.6 0.0 0.0024 18.1 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding OSCP PF00213.13 KND94275.1 - 3.9e-46 157.0 0.4 4.6e-46 156.8 0.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 KND94276.1 - 2.1e-09 35.8 3.7 3.9e-07 28.3 0.1 3.4 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase Histone PF00125.19 KND94277.1 - 3e-19 68.8 0.1 5e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KND94277.1 - 0.00037 20.4 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND94278.1 - 2.1e-22 78.9 0.1 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KND94278.1 - 4.3e-05 23.5 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 KND94279.1 - 7.3e-11 41.5 0.1 1.4e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KND94279.1 - 9.1e-07 28.7 0.1 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND94279.1 - 2.5e-05 24.0 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND94279.1 - 3.2e-05 23.4 0.0 6.6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 KND94280.1 - 1.5e-10 40.9 0.1 2.3e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND94280.1 - 1.7e-08 34.5 0.4 2.1e-08 34.3 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND94280.1 - 2.8e-08 33.7 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND94280.1 - 0.0003 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND94280.1 - 0.0017 18.2 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KND94280.1 - 0.0091 15.9 3.4 0.014 15.3 1.2 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KND94280.1 - 0.11 11.7 0.1 0.31 10.3 0.0 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase 2 BC10 PF06726.7 KND94282.1 - 1.1e-13 51.0 7.5 2.2e-13 49.9 5.2 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Myco_19_kDa PF05481.7 KND94284.1 - 6.9 6.4 10.9 0.59 9.9 1.7 2.3 2 1 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen OSTbeta PF15048.1 KND94285.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein MtrF PF09472.5 KND94285.1 - 1.9 7.8 4.9 3.5 6.9 3.4 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Fungal_trans_2 PF11951.3 KND94286.1 - 5.3e-46 156.9 0.0 6.7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94286.1 - 1.7e-05 24.5 3.7 3.1e-05 23.8 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2183 PF09949.4 KND94288.1 - 4.2e-08 33.0 0.0 8.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Uso1_p115_head PF04869.9 KND94290.1 - 5.1e-103 344.0 0.0 1e-102 343.1 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Methyltransf_18 PF12847.2 KND94290.1 - 1.3e-09 38.5 0.1 2.8e-08 34.3 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94290.1 - 3.4e-09 36.4 0.3 1.4e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND94290.1 - 4.3e-09 36.7 2.2 9.4e-09 35.6 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.8 KND94290.1 - 5.4e-09 35.5 0.1 1.7e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KND94290.1 - 2.7e-06 27.3 1.2 9.2e-06 25.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Uso1_p115_C PF04871.8 KND94290.1 - 4.7e-06 26.5 17.1 4.7e-06 26.5 11.9 3.5 2 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region MTS PF05175.9 KND94290.1 - 1.1e-05 24.8 0.3 1.1e-05 24.8 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KND94290.1 - 2.9e-05 23.8 0.0 6.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND94290.1 - 0.0002 21.8 0.0 0.0006 20.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND94290.1 - 0.00035 20.8 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KND94290.1 - 0.027 13.3 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase NUC130_3NT PF08158.7 KND94290.1 - 0.11 12.7 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 NUC130/3NT domain TehB PF03848.9 KND94290.1 - 0.14 11.3 0.0 0.38 9.8 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TehB OPT PF03169.10 KND94291.1 - 8.6e-123 410.9 20.3 1.2e-122 410.5 14.1 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Vps55 PF04133.9 KND94291.1 - 0.002 17.8 2.8 0.19 11.4 1.5 2.7 2 0 0 2 2 2 2 Vacuolar protein sorting 55 XRN_N PF03159.13 KND94292.1 - 3.4e-106 353.9 0.0 5.2e-106 353.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KND94292.1 - 0.29 11.1 3.9 0.73 9.8 2.7 1.7 1 0 0 1 1 1 0 Zinc knuckle LtrA PF06772.6 KND94293.1 - 1.8e-26 92.8 10.8 2.5e-26 92.4 7.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Myosin_tail_1 PF01576.14 KND94293.1 - 0.17 9.5 0.0 0.23 9.1 0.0 1.1 1 0 0 1 1 1 0 Myosin tail Zn_clus PF00172.13 KND94295.1 - 5.2e-08 32.6 9.4 9.4e-08 31.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND94295.1 - 6.5e-07 28.2 0.4 1.1e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.3 KND94297.1 - 3.5e-58 196.8 0.1 5.9e-58 196.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core zf-RING_2 PF13639.1 KND94299.1 - 6.5e-14 51.4 4.8 1.4e-13 50.4 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KND94299.1 - 5e-07 29.7 1.6 9.4e-07 28.8 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KND94299.1 - 5e-07 29.2 2.1 8.4e-07 28.5 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND94299.1 - 2e-06 27.6 4.3 3.3e-06 27.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND94299.1 - 3.1e-06 26.8 2.0 5.2e-06 26.0 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KND94299.1 - 1.6e-05 24.4 1.9 2.7e-05 23.7 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND94299.1 - 0.0065 16.2 1.4 0.017 14.9 1.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KND94299.1 - 0.021 14.4 2.5 0.038 13.5 1.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 KND94299.1 - 0.067 13.3 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KND94299.1 - 0.086 12.8 0.2 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 KND94299.1 - 0.54 9.9 2.9 1 9.0 2.0 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KND94299.1 - 0.93 9.2 3.6 13 5.6 3.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KND94299.1 - 4.1 7.4 6.4 9.9 6.2 2.9 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain CAP_GLY PF01302.20 KND94300.1 - 1.9e-23 81.8 3.3 2.9e-23 81.3 2.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KND94300.1 - 3.5e-20 72.0 0.0 5.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KND94300.1 - 6.1e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.26 KND94301.1 - 4.8e-10 39.3 3.1 9.1e-09 35.2 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND94301.1 - 2.6e-06 27.4 4.9 0.00071 19.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.7 KND94302.1 - 1.4e-11 44.7 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND94302.1 - 7.5e-05 23.1 0.0 0.00016 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND94302.1 - 0.0002 21.6 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94302.1 - 0.00053 19.6 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND94302.1 - 0.00079 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND94302.1 - 0.027 15.0 0.0 0.058 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DS PF01916.12 KND94303.1 - 2.3e-140 466.9 0.0 2.7e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase RabGAP-TBC PF00566.13 KND94304.1 - 1.4e-48 165.2 0.0 2.1e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KND94306.1 - 1.2e-51 175.3 1.3 4.6e-36 124.3 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND94306.1 - 2.6e-22 79.1 0.3 1.9e-20 73.0 0.2 3.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94306.1 - 5.5e-06 25.5 0.0 1.5e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KND94306.1 - 0.0068 16.1 2.1 0.0097 15.6 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Glycos_transf_1 PF00534.15 KND94307.1 - 1.2e-30 106.1 0.0 2e-28 98.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KND94307.1 - 1.9e-11 44.2 1.2 2.8e-08 33.9 0.1 3.4 2 2 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KND94307.1 - 4.4e-07 30.1 11.5 4.4e-07 30.1 8.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KND94307.1 - 2.5e-06 27.3 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 tRNA-synt_1c PF00749.16 KND94308.1 - 2.5e-89 299.0 0.0 3.4e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KND94308.1 - 1e-35 122.9 0.0 1.9e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KND94308.1 - 2.9e-07 30.8 0.0 7.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND94308.1 - 3.1e-06 26.9 0.1 7.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KND94308.1 - 0.00095 19.1 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pentapeptide_4 PF13599.1 KND94308.1 - 1.2 8.9 3.3 1.6 8.6 0.2 2.5 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Ank_2 PF12796.2 KND94310.1 - 1.6e-103 339.2 0.0 1e-19 70.6 0.0 8.3 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KND94310.1 - 1.9e-86 279.8 7.6 9.9e-07 28.2 0.1 16.3 15 2 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 KND94310.1 - 1.2e-66 219.9 0.8 5.8e-09 36.2 0.0 11.2 4 2 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94310.1 - 3.6e-65 209.3 0.0 0.00017 21.5 0.0 15.6 16 0 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.1 KND94310.1 - 8.1e-57 187.9 8.4 3.6e-07 30.1 0.0 11.2 6 3 5 11 11 11 10 Ankyrin repeats (many copies) GATase_7 PF13537.1 KND94310.1 - 0.13 11.9 0.0 1.2e+02 2.4 0.0 4.6 4 1 1 5 5 5 0 Glutamine amidotransferase domain Beta-lactamase PF00144.19 KND94311.1 - 4.3e-40 137.7 0.2 5.9e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KND94311.1 - 8.7e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) WD40 PF00400.27 KND94312.1 - 2.8e-12 46.0 7.3 5.2e-06 26.1 0.0 5.8 6 1 1 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KND94312.1 - 0.025 14.8 0.5 1.6e+02 2.7 0.0 4.9 4 1 0 4 4 4 0 PQQ-like domain Glyco_hydro_18 PF00704.23 KND94314.1 - 7.2e-102 341.3 4.8 8.4e-102 341.1 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PPTA PF01239.17 KND94315.1 - 6.5e-34 113.8 12.6 1e-06 27.7 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat His_Phos_2 PF00328.17 KND94316.1 - 0.0026 17.1 0.0 0.026 13.8 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Calc_CGRP_IAPP PF00214.14 KND94316.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family JmjC PF02373.17 KND94317.1 - 1.4e-09 38.1 0.0 4.4e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KND94317.1 - 0.00092 19.3 13.8 0.00092 19.3 9.6 2.9 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KND94317.1 - 0.021 14.2 0.0 0.064 12.7 0.0 1.7 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 KND94318.1 - 3.6e-32 111.5 23.1 4.9e-32 111.1 16.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.20 KND94319.1 - 9.6e-41 138.0 0.6 1.1e-40 137.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 AOX PF01786.12 KND94320.1 - 0.096 12.0 0.0 1.4 8.2 0.0 2.0 1 1 1 2 2 2 0 Alternative oxidase Inhibitor_I9 PF05922.11 KND94321.1 - 0.03 14.8 0.1 0.041 14.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 TFIIH_BTF_p62_N PF08567.6 KND94321.1 - 0.062 12.9 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain rRNA_proc-arch PF13234.1 KND94323.1 - 7.6e-89 297.4 0.0 1.3e-88 296.6 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KND94323.1 - 2e-59 199.8 1.5 4.7e-59 198.6 1.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KND94323.1 - 2e-21 76.1 0.0 5.5e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND94323.1 - 1.1e-07 31.5 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KND94323.1 - 0.024 13.5 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TPR_6 PF13174.1 KND94323.1 - 0.024 15.0 0.1 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.18 KND94324.1 - 8.2e-11 42.0 1.4 9.8e-11 41.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KND94324.1 - 0.00011 21.9 2.3 0.0002 21.1 1.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Glyco_hydro_65m PF03632.10 KND94325.1 - 3.8e-71 239.7 0.3 2.8e-70 236.8 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KND94325.1 - 2e-25 89.5 0.0 3.3e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain UCR_TM PF02921.9 KND94326.1 - 0.022 14.9 0.1 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region FAD_binding_4 PF01565.18 KND94327.1 - 1e-23 83.3 0.5 1.6e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KND94327.1 - 0.008 16.0 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like DUF2407_C PF13373.1 KND94328.1 - 6.6e-28 97.3 0.0 9.1e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KND94328.1 - 3.6e-26 91.1 0.0 5.6e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF4589 PF15252.1 KND94328.1 - 0.01 15.6 0.3 0.013 15.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) ubiquitin PF00240.18 KND94328.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Ima1_N PF09779.4 KND94329.1 - 1.2e-36 126.0 4.6 2.1e-36 125.3 3.2 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 KND94329.1 - 0.0098 15.6 3.3 0.99 9.2 0.2 2.5 2 0 0 2 2 2 2 Double zinc ribbon MFS_1 PF07690.11 KND94330.1 - 1.4e-28 99.6 46.4 8.3e-21 74.0 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.19 KND94331.1 - 7.2e-29 100.8 4.2 1.2e-28 100.1 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KND94331.1 - 7.2e-08 31.8 1.0 1.4e-07 30.8 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KND94331.1 - 5e-05 23.5 1.4 0.00012 22.3 1.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KND94331.1 - 0.11 11.8 0.3 0.33 10.2 0.2 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acetyltransf_1 PF00583.19 KND94332.1 - 1.7e-15 56.7 0.1 2.6e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND94332.1 - 4.1e-09 36.5 0.0 4.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND94332.1 - 6.9e-06 26.1 0.0 9.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND94332.1 - 0.00058 19.8 0.0 0.0017 18.3 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND94332.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KND94332.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KND94332.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KND94332.1 - 0.02 14.7 0.0 0.024 14.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FMO-like PF00743.14 KND94334.1 - 3.3e-32 111.4 0.0 1.8e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KND94334.1 - 5.2e-14 52.7 0.0 8.5e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND94334.1 - 7.2e-07 28.4 0.0 6.4e-05 22.0 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KND94334.1 - 1.2e-06 28.6 0.0 0.00019 21.3 0.0 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND94334.1 - 5.5e-05 22.9 0.0 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KND94334.1 - 0.0033 17.4 0.0 0.0083 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND94334.1 - 0.011 14.6 0.1 2.6 6.8 0.0 3.3 3 1 1 4 4 4 0 FAD dependent oxidoreductase DUF2733 PF10813.3 KND94334.1 - 0.066 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) FAD_binding_3 PF01494.14 KND94334.1 - 0.25 10.3 0.2 0.4 9.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PHO4 PF01384.15 KND94335.1 - 2.1e-109 365.1 16.3 2.5e-109 364.8 11.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family PgaD PF13994.1 KND94335.1 - 0.28 10.6 3.9 1.3 8.5 2.7 2.1 1 0 0 1 1 1 0 PgaD-like protein P21-Arc PF04062.9 KND94336.1 - 7.6e-79 263.5 0.0 9.5e-79 263.2 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 KND94336.1 - 0.053 13.5 0.7 0.16 12.0 0.5 1.8 1 0 0 1 1 1 0 Pancreatic hormone peptide Gcd10p PF04189.8 KND94337.1 - 2.4e-79 266.5 0.0 3e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family CTK3 PF12243.3 KND94339.1 - 0.024 14.2 0.3 0.047 13.3 0.2 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Metal_hydrol PF10118.4 KND94339.1 - 0.031 13.7 2.2 0.048 13.1 1.5 1.2 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase FlxA PF14282.1 KND94339.1 - 0.14 12.1 20.0 0.096 12.6 6.0 2.8 2 1 1 3 3 3 0 FlxA-like protein GrpE PF01025.14 KND94339.1 - 0.83 9.1 15.4 0.22 11.0 7.0 2.5 1 1 2 3 3 3 0 GrpE Prefoldin_2 PF01920.15 KND94340.1 - 1.6e-24 85.6 12.1 2.5e-24 85.0 8.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF1319 PF07028.6 KND94340.1 - 0.0098 16.0 1.2 0.0098 16.0 0.9 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1319) LON PF02190.11 KND94340.1 - 0.42 10.2 3.0 0.38 10.3 1.5 1.3 1 1 0 1 1 1 0 ATP-dependent protease La (LON) domain Syntaxin-6_N PF09177.6 KND94340.1 - 0.92 9.9 7.6 2.8 8.4 0.8 2.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KND94340.1 - 1.3 8.9 4.8 5.4 6.9 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) eIF-4B PF06273.6 KND94340.1 - 4.3 5.9 8.2 5.2 5.7 5.7 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Toxin_39 PF15500.1 KND94340.1 - 5.6 7.1 6.8 1.5e+02 2.6 4.2 2.3 1 1 0 1 1 1 0 Putative RNase-like toxin 2OG-FeII_Oxy PF03171.15 KND94341.1 - 4.4e-05 23.7 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KND94341.1 - 0.00069 20.0 0.1 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 KND94342.1 - 3.1e-15 56.4 0.0 6.2e-08 32.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KND94342.1 - 1.6e-08 34.1 0.0 5.5e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin SAM_decarbox PF01536.11 KND94342.1 - 0.14 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Band_7 PF01145.20 KND94343.1 - 4.7e-27 95.0 2.6 7.3e-27 94.4 1.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KND94343.1 - 0.029 13.8 0.2 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family APC10 PF03256.11 KND94344.1 - 4.8e-45 153.5 0.0 8.1e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Nop14 PF04147.7 KND94344.1 - 0.24 9.2 6.4 0.3 8.9 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 KND94344.1 - 0.28 10.8 5.4 0.4 10.3 3.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 KND94344.1 - 0.56 9.7 5.9 0.82 9.1 4.1 1.2 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.4 KND94344.1 - 1.3 7.7 10.1 1.9 7.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 KND94344.1 - 6.1 4.7 6.3 8.7 4.2 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp PF00026.18 KND94345.1 - 1.5e-53 182.0 0.0 1.8e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND94345.1 - 5.6e-08 32.9 0.0 4.3e-06 26.7 0.0 3.3 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KND94345.1 - 7.6e-07 28.8 0.0 2.2e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KND94345.1 - 0.0087 16.5 0.1 9.9 6.7 0.0 3.3 2 1 1 3 3 3 2 Aspartyl protease HSP70 PF00012.15 KND94346.1 - 9.1e-56 188.9 22.4 1.7e-51 174.9 1.5 3.4 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KND94346.1 - 0.0082 14.7 0.0 0.026 13.1 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Allexi_40kDa PF05549.6 KND94346.1 - 0.042 13.1 1.7 0.45 9.7 0.0 2.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein FGGY_C PF02782.11 KND94346.1 - 0.076 12.6 0.2 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Fringe PF02434.11 KND94347.1 - 0.0035 16.5 5.9 0.0065 15.7 2.0 2.6 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.16 KND94347.1 - 0.08 12.5 0.1 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 Galactosyltransferase Cluap1 PF10234.4 KND94348.1 - 0.008 15.4 0.3 0.0095 15.1 0.2 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Spc7 PF08317.6 KND94348.1 - 0.021 13.5 0.6 0.025 13.2 0.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.1 KND94348.1 - 0.021 15.2 1.1 0.031 14.7 0.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CENP-Q PF13094.1 KND94348.1 - 0.021 14.8 0.3 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin PF00261.15 KND94348.1 - 0.04 12.9 0.8 0.05 12.6 0.6 1.1 1 0 0 1 1 1 0 Tropomyosin DUF2360 PF10152.4 KND94348.1 - 0.04 14.1 1.8 0.052 13.8 1.2 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Myosin_tail_1 PF01576.14 KND94348.1 - 0.054 11.2 1.4 0.062 11.0 1.0 1.0 1 0 0 1 1 1 0 Myosin tail Vps51 PF08700.6 KND94348.1 - 0.055 13.3 0.2 0.076 12.8 0.2 1.2 1 0 0 1 1 1 0 Vps51/Vps67 DUF3763 PF12592.3 KND94348.1 - 0.061 12.9 0.4 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Laminin_II PF06009.7 KND94348.1 - 0.062 13.0 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II HR1 PF02185.11 KND94348.1 - 0.072 12.8 0.5 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Hr1 repeat BBP1_C PF15272.1 KND94348.1 - 0.11 12.0 1.4 0.23 10.9 1.0 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal GreA_GreB_N PF03449.10 KND94348.1 - 0.18 11.9 1.1 0.48 10.5 0.8 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal SlyX PF04102.7 KND94348.1 - 0.72 10.2 6.4 3.4 8.1 4.4 2.1 1 1 0 1 1 1 0 SlyX UNC45-central PF11701.3 KND94349.1 - 1.4e-45 154.7 0.0 1.7e-44 151.2 0.0 2.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.18 KND94349.1 - 0.00039 20.1 10.1 0.083 12.7 0.0 6.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KND94349.1 - 1.1 9.6 20.6 5.3e+02 0.9 0.0 6.0 4 1 0 4 4 4 0 HEAT repeats Fungal_trans PF04082.13 KND94350.1 - 1.5e-15 56.7 0.1 2.7e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94350.1 - 2.7e-07 30.3 12.7 5.1e-07 29.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 KND94350.1 - 0.55 8.4 3.3 0.74 8.0 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 KND94350.1 - 0.99 7.5 15.1 1.3 7.1 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Steroid_dh PF02544.11 KND94353.1 - 5.7e-27 94.3 0.4 8.3e-27 93.8 0.3 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KND94353.1 - 6.7e-05 22.2 0.6 0.00011 21.6 0.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Flavi_NS4B PF01349.12 KND94353.1 - 0.0055 15.6 0.0 0.25 10.2 0.0 2.1 2 0 0 2 2 2 2 Flavivirus non-structural protein NS4B PEMT PF04191.8 KND94353.1 - 0.033 14.3 1.2 0.046 13.8 0.1 1.8 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF1682 PF07946.9 KND94353.1 - 0.081 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Diphthamide_syn PF01866.12 KND94354.1 - 1.4e-110 369.3 0.0 2.5e-110 368.5 0.0 1.4 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Aldose_epim PF01263.15 KND94354.1 - 1.2e-46 159.1 0.0 2.4e-46 158.2 0.0 1.4 1 1 0 1 1 1 1 Aldose 1-epimerase HMGL-like PF00682.14 KND94355.1 - 7.8e-40 137.0 0.2 4e-39 134.6 0.1 1.8 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.20 KND94356.1 - 1.7e-59 200.9 0.0 2.5e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KND94356.1 - 6.5e-17 62.0 0.2 1.2e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KND94356.1 - 9.9e-13 48.1 0.9 2e-12 47.1 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KND94356.1 - 0.00015 21.5 0.5 0.00033 20.4 0.3 1.6 1 0 0 1 1 1 1 HAS barrel domain IFRD_C PF04836.7 KND94356.1 - 0.15 12.3 0.1 5.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Interferon-related protein conserved region DUF913 PF06025.7 KND94357.1 - 2.5e-106 355.6 0.0 2.5e-106 355.6 0.0 4.5 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KND94357.1 - 2.7e-96 322.4 0.2 5.2e-96 321.5 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KND94357.1 - 8.3e-88 294.8 0.0 8.3e-88 294.8 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KND94357.1 - 2.3e-30 104.6 8.0 2.3e-30 104.6 5.5 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) Trp_Tyr_perm PF03222.8 KND94357.1 - 7.6 5.2 0.1 13 4.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family RabGAP-TBC PF00566.13 KND94359.1 - 2.8e-46 157.6 0.1 3.8e-45 153.9 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HALZ PF02183.13 KND94359.1 - 0.025 14.2 16.4 0.46 10.2 0.7 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper CCDC155 PF14662.1 KND94359.1 - 0.38 10.3 37.2 0.026 14.1 6.7 2.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KND94359.1 - 0.45 10.8 21.6 0.28 11.5 2.9 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Ctf8 PF09696.5 KND94360.1 - 7e-32 109.7 0.0 8.7e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.14 KND94361.1 - 6.6e-61 203.5 0.1 1.3e-60 202.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 KND94361.1 - 0.14 12.1 0.8 0.2 11.6 0.3 1.5 2 0 0 2 2 2 0 Cadherin cytoplasmic region EF-1_beta_acid PF10587.4 KND94361.1 - 0.37 10.9 3.4 0.95 9.6 2.4 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Pribosyl_synth PF14572.1 KND94362.1 - 4.5e-43 147.1 0.5 6.1e-37 127.1 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KND94362.1 - 1.1e-29 102.5 0.0 4.9e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KND94362.1 - 4.5e-11 42.5 0.1 1.2e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AviRa PF11599.3 KND94362.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PARP PF00644.15 KND94363.1 - 2.2e-10 40.3 0.0 4.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KND94363.1 - 2.8e-06 26.8 0.0 7.9e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme PIG-H PF10181.4 KND94364.1 - 6.7e-26 89.7 0.0 9.5e-26 89.2 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF1180 PF06679.7 KND94364.1 - 1.3 8.8 3.9 2 8.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PseudoU_synth_1 PF01416.15 KND94365.1 - 6.9e-28 97.1 0.0 1.6e-21 76.7 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase RNA_pol_Rpb4 PF03874.11 KND94366.1 - 5.8e-24 84.3 0.0 7.3e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 FEZ PF07763.8 KND94366.1 - 0.029 14.1 0.2 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 FEZ-like protein Anti-adapt_IraP PF10796.4 KND94366.1 - 0.13 12.6 0.4 0.36 11.2 0.3 1.7 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein Glyco_transf_54 PF04666.8 KND94366.1 - 0.14 10.8 0.1 0.2 10.3 0.0 1.3 1 1 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Ras PF00071.17 KND94367.1 - 4.1e-17 62.0 0.0 1.4e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KND94367.1 - 2.2e-08 34.6 0.0 2.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 KND94367.1 - 0.00014 21.1 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family PduV-EutP PF10662.4 KND94367.1 - 0.035 13.6 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KND94367.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KND94367.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.16 KND94368.1 - 1.7e-19 69.8 2.5 1.7e-19 69.8 1.7 1.8 2 0 0 2 2 2 1 Snf7 WASH_WAHD PF11945.3 KND94368.1 - 0.2 10.9 4.1 3 7.0 0.1 2.2 2 0 0 2 2 2 0 WAHD domain of WASH complex DUF737 PF05300.6 KND94369.1 - 0.00039 20.4 1.1 0.00043 20.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) MTBP_mid PF14919.1 KND94369.1 - 0.081 11.5 0.5 0.14 10.8 0.3 1.3 1 0 0 1 1 1 0 MDM2-binding DIRP PF06584.8 KND94369.1 - 0.14 12.0 2.3 0.26 11.1 1.6 1.5 1 0 0 1 1 1 0 DIRP GDPD PF03009.12 KND94373.1 - 9.6e-69 231.7 0.0 1.7e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KND94373.1 - 2.6e-29 101.3 0.4 1.8e-09 37.8 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) SPX PF03105.14 KND94373.1 - 2.8e-28 99.4 0.9 4.8e-15 56.0 0.3 3.6 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KND94373.1 - 8.8e-28 96.1 2.7 9.5e-09 35.5 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 KND94373.1 - 5.6e-23 79.5 1.7 1.2e-05 24.8 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KND94373.1 - 6.4e-20 70.7 0.3 6.4e-06 26.2 0.0 5.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94373.1 - 1.4e-12 46.5 2.8 0.00097 19.1 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat RebB PF11747.3 KND94373.1 - 0.086 12.7 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Killing trait adh_short PF00106.20 KND94374.1 - 9.4e-30 103.7 4.4 1.2e-29 103.3 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND94374.1 - 1.3e-27 97.0 0.7 1.7e-27 96.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND94374.1 - 5.9e-11 42.3 4.0 1.9e-10 40.7 2.8 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KND94374.1 - 0.0025 17.2 0.3 0.005 16.3 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SKG6 PF08693.5 KND94375.1 - 0.0011 18.2 0.8 0.0029 16.9 0.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KND94375.1 - 0.043 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Peptidase_M41 PF01434.13 KND94376.1 - 8.9e-64 214.8 1.7 1.4e-63 214.2 1.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KND94376.1 - 3.8e-42 143.6 0.0 9.6e-42 142.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND94376.1 - 1.1e-06 28.4 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND94376.1 - 1.5e-06 28.3 0.6 8.3e-05 22.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND94376.1 - 1.1e-05 26.2 0.0 3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND94376.1 - 6e-05 23.0 1.4 0.0015 18.5 1.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 KND94376.1 - 6.5e-05 21.8 0.0 0.00012 20.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KND94376.1 - 6.5e-05 22.0 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KND94376.1 - 0.00083 18.8 1.0 0.27 10.5 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KND94376.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND94376.1 - 0.0012 18.5 0.2 0.0033 17.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KND94376.1 - 0.0021 17.5 0.4 0.0059 16.0 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 KND94376.1 - 0.003 17.4 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND94376.1 - 0.0046 16.0 1.1 0.019 14.0 0.2 2.2 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KND94376.1 - 0.017 14.3 0.9 0.036 13.2 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KND94376.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KND94376.1 - 0.056 13.3 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KND94376.1 - 0.056 13.1 1.0 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KND94376.1 - 0.082 12.9 0.0 0.33 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KND94376.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KND94376.1 - 0.11 11.7 0.2 0.26 10.5 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-H2C2_2 PF13465.1 KND94377.1 - 7.1e-21 73.3 28.2 5.3e-08 32.7 0.4 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KND94377.1 - 1.7e-20 72.0 29.4 1.3e-05 25.2 1.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND94377.1 - 8.4e-11 41.4 26.0 0.00046 20.3 1.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND94377.1 - 0.00013 21.9 4.9 1.3 9.3 0.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND94377.1 - 0.0054 16.8 10.9 0.012 15.7 0.4 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KND94377.1 - 0.0077 16.5 14.8 0.021 15.2 1.4 3.4 1 1 2 3 3 3 2 TRAF-type zinc finger Rz1 PF06085.6 KND94377.1 - 0.11 11.8 3.5 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor zf-C2HC_2 PF13913.1 KND94377.1 - 0.81 9.4 5.8 30 4.4 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type CHORD PF04968.7 KND94377.1 - 3.6 7.9 16.1 3.7 7.8 0.2 4.2 1 1 3 4 4 4 0 CHORD CCAP PF11105.3 KND94377.1 - 4.8 6.9 8.7 11 5.7 0.3 3.6 2 1 2 4 4 4 0 Arthropod cardioacceleratory peptide 2a Metallophos PF00149.23 KND94378.1 - 2.6e-37 128.1 0.0 2.4e-32 111.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Met_10 PF02475.11 KND94379.1 - 0.00015 21.4 0.0 0.0004 20.0 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KND94379.1 - 0.0031 17.5 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_6 PF13405.1 KND94380.1 - 5.2e-09 35.2 0.1 0.0028 17.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KND94380.1 - 6.4e-06 26.2 0.6 0.00099 19.2 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KND94380.1 - 1.3e-05 24.3 0.1 0.00081 18.6 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 KND94380.1 - 0.00065 18.8 0.1 0.0057 15.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KND94380.1 - 0.0061 16.1 0.5 0.039 13.5 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain pair ORC6 PF05460.8 KND94381.1 - 9.3e-33 113.7 6.7 5.2e-32 111.3 4.6 1.9 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Frataxin_Cyay PF01491.11 KND94382.1 - 9.1e-34 115.5 0.0 1.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.15 KND94383.1 - 7.1e-39 132.7 0.0 2.7e-38 130.8 0.0 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sugar_tr PF00083.19 KND94385.1 - 3.9e-103 345.4 15.7 4.7e-103 345.1 10.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND94385.1 - 1.1e-24 86.8 33.1 5.2e-20 71.4 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND94385.1 - 2.1e-06 26.4 23.4 0.00021 19.8 3.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KND94385.1 - 0.0029 16.3 2.2 0.0047 15.6 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 KND94385.1 - 0.28 9.2 5.7 0.21 9.6 0.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 KND94387.1 - 4.6e-92 308.1 9.8 5.8e-92 307.8 6.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3681 PF12442.3 KND94387.1 - 0.014 15.5 0.1 0.075 13.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) DUF973 PF06157.6 KND94387.1 - 9.5 5.0 12.7 5.6 5.8 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF973) DUF2448 PF10476.4 KND94388.1 - 0.0037 16.8 0.9 0.0051 16.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) DUF2306 PF10067.4 KND94388.1 - 0.26 11.4 5.7 4 7.6 0.9 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Glyoxalase PF00903.20 KND94389.1 - 5.6e-21 74.8 0.0 3.7e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KND94389.1 - 5.5e-12 45.6 0.1 9.1e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KND94389.1 - 3.4e-10 40.4 0.1 0.00069 20.2 0.1 2.7 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KND94389.1 - 0.00026 20.9 0.0 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KND94389.1 - 0.065 13.1 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.9 KND94390.1 - 6.5e-74 247.7 0.0 8.4e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KND94390.1 - 1.2e-16 60.3 10.8 1.2e-16 60.3 7.5 2.7 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KND94390.1 - 2.7e-10 40.6 0.0 4.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KND94390.1 - 0.035 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain tRNA-synt_1 PF00133.17 KND94392.1 - 6.7e-35 120.1 0.0 2.8e-25 88.4 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KND94392.1 - 1.6e-15 56.7 0.1 7.9e-10 37.9 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KND94392.1 - 2.6e-11 43.5 0.2 5.3e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KND94392.1 - 7.1e-07 28.6 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Herpes_UL49_5 PF05702.6 KND94392.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein DUF2419 PF10343.4 KND94393.1 - 1.8e-120 401.5 0.1 3.4e-120 400.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) DNA_pol_delta_4 PF04081.8 KND94394.1 - 9.4e-29 100.2 0.9 1.3e-28 99.7 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 NYD-SP28 PF14772.1 KND94394.1 - 0.017 15.2 3.2 0.031 14.3 2.2 1.4 1 0 0 1 1 1 0 Sperm tail adh_short_C2 PF13561.1 KND94395.1 - 2.7e-10 40.4 0.0 3.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND94395.1 - 0.0073 16.2 0.5 0.013 15.4 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase ThiF PF00899.16 KND94396.1 - 5.8e-41 139.5 0.4 1.3e-40 138.3 0.3 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KND94396.1 - 5.5e-28 96.3 0.3 5.5e-28 96.3 0.2 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KND94396.1 - 9.1e-21 73.7 1.1 9.1e-21 73.7 0.8 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KND94396.1 - 5.8e-19 67.2 0.7 1.5e-18 65.9 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KND94396.1 - 0.00089 19.3 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KND94396.1 - 0.00093 19.4 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KND94396.1 - 0.039 14.3 0.2 0.34 11.3 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PAP2 PF01569.16 KND94397.1 - 5.8e-18 64.8 3.9 2.3e-17 62.8 2.7 2.0 1 0 0 1 1 1 1 PAP2 superfamily adh_short PF00106.20 KND94398.1 - 2.4e-11 43.8 0.1 0.00025 21.0 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KND94398.1 - 0.00038 20.2 0.0 0.00064 19.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KND94398.1 - 0.0031 17.0 0.0 0.0067 15.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KND94398.1 - 0.0034 17.0 0.1 0.0048 16.5 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 KND94398.1 - 0.0057 16.3 0.2 0.23 11.1 0.1 2.4 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KND94398.1 - 0.0066 16.4 0.4 0.058 13.4 0.2 2.1 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KND94398.1 - 0.031 13.5 0.1 0.042 13.1 0.1 1.1 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 KND94398.1 - 0.058 13.7 0.4 0.2 11.9 0.2 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KND94398.1 - 0.079 12.0 0.1 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.22 KND94398.1 - 0.14 12.5 0.2 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 KND94399.1 - 7.5e-20 71.0 0.0 1.8e-09 37.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND94399.1 - 2.7e-18 64.7 2.6 5.9e-06 25.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KND94399.1 - 3.1e-14 53.0 2.0 0.00011 22.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94399.1 - 5.2e-13 47.8 0.1 0.0017 18.4 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KND94399.1 - 7.6e-12 45.0 1.8 0.0053 16.9 0.0 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KND94399.1 - 0.025 14.1 0.0 2.4 7.5 0.0 2.0 2 0 0 2 2 2 0 Shigella flexneri OspC protein PTR2 PF00854.16 KND94400.1 - 4.6e-45 154.0 10.9 8.7e-45 153.0 7.5 1.5 1 1 0 1 1 1 1 POT family Septin PF00735.13 KND94401.1 - 2.8e-113 377.6 0.3 3.3e-113 377.3 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KND94401.1 - 2.5e-06 27.4 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KND94401.1 - 3.4e-06 26.3 0.0 6.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KND94401.1 - 3.3e-05 23.1 0.0 6.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KND94401.1 - 4.2e-05 23.0 0.1 0.0064 15.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KND94401.1 - 0.0011 18.8 0.3 1.5 8.6 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KND94401.1 - 0.0037 16.7 0.1 0.004 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KND94401.1 - 0.0049 16.0 0.0 0.071 12.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 KND94401.1 - 0.0076 16.5 0.2 0.014 15.7 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KND94401.1 - 0.0095 16.2 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND94401.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KND94401.1 - 0.017 14.0 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 KND94401.1 - 0.024 14.6 0.1 0.06 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KND94401.1 - 0.042 13.3 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 KND94401.1 - 0.053 12.4 0.1 0.12 11.2 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KND94401.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRF PF08558.5 KND94402.1 - 7.9e-22 77.7 0.0 1.7e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KND94402.1 - 1.5e-06 28.1 0.1 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND94402.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Fic PF02661.13 KND94403.1 - 2.5e-18 66.5 0.0 6.9e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family Bromodomain PF00439.20 KND94404.1 - 9.1e-11 41.5 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain PIGA PF08288.7 KND94405.1 - 3.5e-46 155.4 1.4 3.5e-46 155.4 1.0 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KND94405.1 - 1.1e-29 103.0 0.0 1.7e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KND94405.1 - 2.1e-15 57.0 0.0 4.6e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KND94405.1 - 7.3e-15 55.1 0.7 1.3e-14 54.3 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KND94405.1 - 3e-13 50.2 0.0 4.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KND94405.1 - 1.5e-05 24.8 0.1 2.4e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KND94405.1 - 0.0015 18.7 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Rgp1 PF08737.5 KND94406.1 - 2.8e-120 402.2 0.0 3e-119 398.7 0.0 2.2 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 KND94406.1 - 0.048 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.27 KND94407.1 - 4.4e-19 67.5 12.1 2.2e-06 27.3 0.0 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KND94407.1 - 0.0022 17.4 1.0 1.7 8.0 0.0 4.3 3 2 1 5 5 5 2 PQQ-like domain PQQ_3 PF13570.1 KND94407.1 - 0.28 11.5 10.9 10 6.5 0.4 5.8 7 0 0 7 7 7 0 PQQ-like domain DEAD PF00270.24 KND94409.1 - 2.4e-34 118.2 0.0 5.5e-34 117.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KND94409.1 - 5.5e-21 73.8 0.0 9.8e-21 73.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KND94409.1 - 3.7e-18 65.1 0.0 7.1e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KND94409.1 - 0.0046 16.6 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KND94409.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CTP_transf_1 PF01148.15 KND94410.1 - 1.9e-17 63.7 10.5 3.9e-15 56.2 5.3 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF2244 PF10003.4 KND94410.1 - 4.9 6.5 7.5 1.1 8.6 0.5 2.6 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) PRMT5 PF05185.11 KND94411.1 - 9.3e-146 486.2 0.0 5e-144 480.5 0.0 2.0 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CRM1_C PF08767.6 KND94412.1 - 5.7e-122 406.6 4.3 5.7e-122 406.6 3.0 3.7 3 2 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KND94412.1 - 8.6e-41 139.2 14.9 8.9e-41 139.2 6.0 3.8 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KND94412.1 - 1.2e-10 41.1 0.0 5.2e-10 39.1 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 KND94412.1 - 0.026 14.4 1.8 0.57 10.0 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) KOW PF00467.24 KND94413.1 - 6.8e-08 31.9 1.8 1.9e-07 30.4 1.2 1.8 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.6 KND94413.1 - 0.067 13.0 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) LEA_1 PF03760.10 KND94413.1 - 0.24 11.5 1.2 0.85 9.8 0.1 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 SNARE PF05739.14 KND94414.1 - 6.7e-09 35.3 0.5 9.2e-09 34.8 0.4 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KND94414.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Apc15p PF05841.6 KND94415.1 - 4.1e-21 76.0 3.2 8.4e-20 71.7 2.2 2.7 1 1 0 1 1 1 1 Apc15p protein TFIIA PF03153.8 KND94415.1 - 0.00025 21.0 14.0 0.00025 21.0 9.7 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Na_H_Exchanger PF00999.16 KND94416.1 - 1.9e-44 151.7 19.8 2.6e-44 151.2 13.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KND94416.1 - 0.11 12.5 0.8 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 YrhC-like protein EthD PF07110.6 KND94418.1 - 6.6e-11 43.0 1.6 1.2e-10 42.2 1.0 1.5 1 1 1 2 2 2 1 EthD domain Ank PF00023.25 KND94419.1 - 1.2e-16 59.5 1.3 3.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KND94419.1 - 4.2e-14 52.6 0.1 8.3e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 KND94419.1 - 9.2e-12 44.8 0.5 3e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.1 KND94419.1 - 4.1e-11 42.7 1.2 8.2e-09 35.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND94419.1 - 2.7e-10 40.4 0.3 6.8e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94419.1 - 5.7e-09 35.3 0.4 0.0028 17.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Velvet PF11754.3 KND94420.1 - 2e-64 216.9 0.0 3.4e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Arm PF00514.18 KND94421.1 - 1.7e-07 30.7 0.7 0.0031 17.2 0.0 5.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KND94421.1 - 0.00041 20.1 8.6 0.49 10.6 0.1 6.7 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 KND94421.1 - 0.033 14.7 14.4 18 5.9 0.6 6.5 6 0 0 6 6 6 0 HEAT-like repeat Cyclin PF08613.6 KND94422.1 - 6.6e-28 97.9 0.0 1.3e-27 97.0 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KND94422.1 - 0.0022 17.5 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain SOG2 PF10428.4 KND94422.1 - 1.1 7.8 10.9 1.4 7.4 7.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 KND94422.1 - 4.4 6.6 25.6 6 6.1 17.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF2556 PF10831.3 KND94423.1 - 0.14 11.7 0.6 0.25 11.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) TraW_N PF12477.3 KND94423.1 - 0.67 9.9 4.8 0.18 11.8 0.9 1.9 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Het-C PF07217.6 KND94424.1 - 7.8e-284 942.5 0.0 8.9e-284 942.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.16 KND94425.1 - 1.3e-38 132.8 0.0 3.5e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KND94425.1 - 0.00022 20.7 0.0 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Metallophos PF00149.23 KND94427.1 - 1.2e-08 34.5 2.6 2.3e-08 33.6 1.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND94427.1 - 5.2e-06 26.3 0.0 9.6e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VWA_2 PF13519.1 KND94429.1 - 5e-06 26.7 0.0 6.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KND94429.1 - 0.019 14.6 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Cyt-b5 PF00173.23 KND94430.1 - 1.1e-18 66.7 0.1 5.2e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KND94430.1 - 2.1e-08 34.5 22.7 3e-08 34.0 14.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 KND94430.1 - 0.09 12.7 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 KND94430.1 - 0.24 11.0 1.7 0.49 10.0 0.2 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.17 KND94431.1 - 2.3e-41 139.2 2.8 1.4e-18 66.2 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94431.1 - 8.3e-33 112.1 0.6 1.7e-14 53.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KND94431.1 - 1.3e-29 102.2 0.2 2.8e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KND94431.1 - 1.8e-17 62.9 0.1 2.3e-06 27.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KND94431.1 - 0.021 14.6 1.0 0.79 9.5 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif Aminotran_1_2 PF00155.16 KND94432.1 - 6.3e-34 117.4 0.0 8.4e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KND94432.1 - 0.045 12.9 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase DLH PF01738.13 KND94434.1 - 1.4e-22 80.0 0.0 2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND94434.1 - 0.00014 21.6 0.1 0.00019 21.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KND94434.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MS_channel PF00924.13 KND94435.1 - 1.6e-18 66.8 2.1 2.1e-18 66.4 1.5 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel Mito_carr PF00153.22 KND94436.1 - 4.6e-30 103.1 5.4 7.8e-13 47.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KND94437.1 - 1.6e-10 40.4 8.0 0.15 11.9 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat RTX PF02382.10 KND94437.1 - 0.36 9.0 0.0 0.53 8.4 0.0 1.1 1 0 0 1 1 1 0 RTX N-terminal domain Abp2 PF09441.5 KND94438.1 - 2.5e-74 248.9 0.0 3.9e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Mito_fiss_reg PF05308.6 KND94438.1 - 3 7.1 10.0 4 6.7 6.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator Sugar_tr PF00083.19 KND94440.1 - 7.7e-85 285.1 20.0 9.6e-85 284.8 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND94440.1 - 1.7e-10 40.1 43.7 2.8e-07 29.5 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 KND94441.1 - 3.6e-29 101.6 0.0 6.9e-29 100.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND94441.1 - 4.4e-10 39.8 0.0 6.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KND94441.1 - 9.3e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KND94441.1 - 0.00076 18.9 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND94441.1 - 0.011 14.4 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KND94441.1 - 0.032 14.1 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Saccharop_dh PF03435.13 KND94441.1 - 0.038 12.9 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Sds3 PF08598.6 KND94442.1 - 1.5e-37 129.1 12.7 2.2e-37 128.6 8.8 1.5 1 1 0 1 1 1 1 Sds3-like Stm1_N PF09598.5 KND94443.1 - 0.52 11.0 5.5 0.42 11.3 3.2 1.4 1 1 0 1 1 1 0 Stm1 Cpn60_TCP1 PF00118.19 KND94444.1 - 3.9e-160 533.6 0.1 4.4e-160 533.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 KND94445.1 - 1.9e-40 137.6 6.7 1.9e-40 137.6 4.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) RNA_polI_A34 PF08208.6 KND94445.1 - 0.034 13.8 5.0 0.042 13.5 3.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.11 KND94445.1 - 1.7 8.1 14.5 2.6 7.5 10.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNase_H2-Ydr279 PF09468.5 KND94445.1 - 2.4 7.2 5.7 3.2 6.8 3.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 KND94445.1 - 7.6 6.3 6.4 11 5.7 4.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal His_Phos_1 PF00300.17 KND94446.1 - 4.4e-32 111.3 1.3 7.5e-32 110.6 0.0 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KND94446.1 - 0.0032 16.8 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HATPase_c PF02518.21 KND94447.1 - 1e-24 86.3 0.2 2.5e-24 85.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KND94447.1 - 1.2e-21 76.8 0.1 3.3e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KND94447.1 - 5.5e-21 74.3 0.5 2.1e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KND94447.1 - 4.6e-20 71.5 1.0 2.5e-11 43.5 0.1 3.8 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.1 KND94447.1 - 1.5e-10 41.3 0.0 0.00014 22.1 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KND94447.1 - 3.6e-06 26.9 0.0 8.6e-05 22.5 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KND94447.1 - 1.7e-05 24.5 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold CPT PF07931.7 KND94447.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UPF0565 PF10561.4 KND94447.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Sec6 PF06046.8 KND94448.1 - 1.1e-159 532.2 10.4 1.7e-159 531.5 7.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KND94448.1 - 0.00042 19.2 2.2 0.00072 18.4 0.2 2.3 2 0 0 2 2 2 1 Vps53-like, N-terminal FAD_binding_2 PF00890.19 KND94448.1 - 0.00072 18.5 0.1 0.0035 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain OmdA PF13376.1 KND94448.1 - 0.037 13.6 0.7 0.23 11.1 0.0 2.7 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated MutS_III PF05192.13 KND94448.1 - 0.15 11.8 3.3 3.3 7.4 2.3 3.3 1 1 0 1 1 1 0 MutS domain III DUF2018 PF09442.5 KND94448.1 - 0.22 12.0 3.8 14 6.2 0.3 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) Pyr_redox_2 PF07992.9 KND94449.1 - 2.3e-38 132.1 0.2 3.7e-38 131.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KND94449.1 - 1.4e-31 108.8 0.1 5.4e-31 106.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KND94449.1 - 5.4e-20 71.5 2.8 1e-18 67.4 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND94449.1 - 9.7e-12 45.3 0.2 1.6e-08 34.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND94449.1 - 2.7e-05 23.2 0.0 0.012 14.5 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KND94449.1 - 0.0054 15.2 2.6 0.28 9.6 0.0 2.9 2 1 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KND94449.1 - 0.014 14.9 0.8 0.61 9.6 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KND94449.1 - 0.038 13.0 0.4 0.097 11.7 0.3 1.6 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KND94449.1 - 0.041 13.5 0.0 0.041 13.5 0.0 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KND94449.1 - 0.17 10.9 1.0 15 4.5 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KND94449.1 - 0.57 9.3 3.9 0.5 9.4 0.0 2.7 3 1 1 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KND94449.1 - 0.67 8.7 5.6 2.4 6.9 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Ecl1 PF12855.2 KND94450.1 - 3e-10 39.2 0.8 3e-10 39.2 0.5 1.7 2 0 0 2 2 2 1 Life-span regulatory factor Metallothio_Pro PF02069.11 KND94450.1 - 0.0097 15.7 2.5 0.022 14.5 1.7 1.6 1 0 0 1 1 1 1 Prokaryotic metallothionein zf-ribbon_3 PF13248.1 KND94450.1 - 0.09 12.0 0.2 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-MYND PF01753.13 KND94450.1 - 0.17 11.7 2.9 0.41 10.5 2.0 1.6 1 0 0 1 1 1 0 MYND finger DUF2116 PF09889.4 KND94450.1 - 0.24 11.2 1.5 0.57 10.0 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF605 PF04652.11 KND94450.1 - 3.4 6.9 10.2 3.9 6.7 7.1 1.0 1 0 0 1 1 1 0 Vta1 like Allantoicase PF03561.10 KND94452.1 - 6.6e-104 343.8 0.1 5.4e-56 188.2 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Aldo_ket_red PF00248.16 KND94453.1 - 4e-46 157.1 0.0 4.7e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 KND94454.1 - 1.6e-117 392.8 0.0 2e-117 392.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family XRCC4 PF06632.7 KND94456.1 - 2.2e-06 26.7 14.6 3.9e-06 25.9 10.1 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 V_ATPase_I PF01496.14 KND94456.1 - 0.34 8.6 4.3 0.46 8.2 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Blt1 PF12754.2 KND94457.1 - 1.5e-34 119.9 2.6 6.3e-29 101.5 0.2 2.3 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KND94457.1 - 2.3e-05 23.6 0.1 4.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Nol1_Nop2_Fmu PF01189.12 KND94458.1 - 5.8e-98 327.7 0.0 8e-98 327.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KND94458.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KND94458.1 - 0.006 17.1 0.0 0.021 15.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94458.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Toprim_Crpt PF13342.1 KND94458.1 - 0.036 13.7 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase PCMT PF01135.14 KND94458.1 - 0.059 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF148 PF02520.12 KND94459.1 - 0.2 11.4 3.7 0.58 9.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF148 Cpn60_TCP1 PF00118.19 KND94460.1 - 1.1e-118 397.0 9.0 1.3e-118 396.7 6.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 KND94460.1 - 1.5e-30 105.6 1.1 2.6e-30 104.8 0.3 1.8 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein Death PF00531.17 KND94461.1 - 0.097 12.4 0.0 0.29 10.9 0.0 1.8 1 1 1 2 2 2 0 Death domain Med3 PF11593.3 KND94462.1 - 0.22 10.7 4.6 0.24 10.6 3.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Alpha_GJ PF03229.8 KND94462.1 - 0.52 10.6 3.5 0.63 10.3 2.1 1.4 1 1 0 1 1 1 0 Alphavirus glycoprotein J Pox_Ag35 PF03286.9 KND94462.1 - 8.4 5.8 13.7 6.5 6.2 8.1 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein tRNA_U5-meth_tr PF05958.6 KND94463.1 - 3.1e-12 45.8 0.0 1e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 KND94463.1 - 2.4e-07 30.4 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KND94463.1 - 3.7e-06 26.6 0.0 6.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KND94463.1 - 1.7e-05 24.5 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 KND94463.1 - 0.003 18.1 0.0 0.0079 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain G_glu_transpept PF01019.16 KND94464.1 - 5.7e-152 506.7 4.7 6.5e-152 506.5 3.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.13 KND94466.1 - 7.2e-32 110.3 8.4 3.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 KND94467.1 - 7.4e-97 323.9 0.0 8.6e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KND94467.1 - 0.00061 19.9 2.5 0.001 19.1 1.8 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain ADH_zinc_N PF00107.21 KND94468.1 - 4.6e-29 100.5 0.4 7.4e-29 99.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND94468.1 - 6.6e-29 99.8 0.2 1.1e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND94468.1 - 0.00089 20.1 0.2 0.0015 19.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KND94468.1 - 0.022 13.8 0.2 0.055 12.6 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KND94468.1 - 0.074 13.0 0.3 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding Actin PF00022.14 KND94469.1 - 2.2e-81 273.3 0.0 6.9e-81 271.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KND94469.1 - 0.032 12.8 0.1 1.5 7.3 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Agglutinin PF07468.6 KND94469.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Agglutinin PP2C PF00481.16 KND94471.1 - 1e-39 136.4 0.0 1.9e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KND94471.1 - 0.00091 18.6 0.0 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KND94471.1 - 0.003 17.2 0.2 0.059 13.0 0.0 2.6 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) SLAC1 PF03595.12 KND94472.1 - 0.0033 16.1 14.9 0.017 13.8 7.8 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel Uds1 PF15456.1 KND94474.1 - 2.5e-42 143.7 0.7 2.5e-42 143.7 0.5 6.7 3 2 4 7 7 7 2 Up-regulated During Septation Reo_sigmaC PF04582.7 KND94474.1 - 0.0015 17.8 11.5 0.19 10.8 3.7 2.6 1 1 1 2 2 2 2 Reovirus sigma C capsid protein MtrB PF05440.7 KND94474.1 - 0.097 12.7 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Tcp11 PF05794.8 KND94475.1 - 4.8e-81 272.7 1.2 1.7e-73 247.8 0.6 2.0 2 0 0 2 2 2 2 T-complex protein 11 Peptidase_M75 PF09375.5 KND94475.1 - 0.042 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Imelysin DUF1242 PF06842.7 KND94477.1 - 3.2e-18 64.9 0.2 4.6e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF3317 PF11779.3 KND94477.1 - 0.084 12.3 0.4 0.084 12.3 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) TFIID-18kDa PF02269.11 KND94478.1 - 1.5e-18 66.3 0.1 2.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KND94478.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KND94478.1 - 0.0035 17.4 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DGF-1_C PF11040.3 KND94478.1 - 0.032 14.1 1.6 0.054 13.3 1.1 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CENP-S PF15630.1 KND94478.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S EamA PF00892.15 KND94479.1 - 3.5e-21 75.5 18.9 3.1e-11 43.4 3.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KND94479.1 - 5.6e-06 26.5 28.3 0.0028 17.8 5.7 3.6 2 2 0 3 3 3 2 Multidrug resistance efflux transporter RasGEF PF00617.14 KND94480.1 - 1.5e-47 161.7 0.6 2.6e-47 160.9 0.4 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KND94480.1 - 2e-11 43.9 0.0 5.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KND94480.1 - 9.3e-11 42.2 0.0 4.7e-10 39.9 0.0 2.2 3 0 0 3 3 3 1 Miro-like protein Ras PF00071.17 KND94480.1 - 0.16 11.3 0.2 23 4.3 0.1 2.9 2 1 0 2 2 2 0 Ras family zf-HIT PF04438.11 KND94482.1 - 4.7e-10 38.9 11.7 8.5e-10 38.1 8.1 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KND94482.1 - 0.00013 21.7 6.6 0.00013 21.7 4.5 1.7 2 0 0 2 2 2 1 MYND finger Nfu_N PF08712.6 KND94483.1 - 9.3e-29 98.8 0.0 2.8e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KND94483.1 - 3.1e-22 78.1 0.0 6.9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 KND94484.1 - 9.1e-31 105.6 0.5 9.1e-31 105.6 0.4 2.0 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 KND94484.1 - 0.36 8.6 0.4 0.51 8.1 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Mitofilin PF09731.4 KND94486.1 - 0.14 10.7 6.8 0.17 10.5 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_L15e PF00827.12 KND94487.1 - 1.5e-91 305.1 12.6 1.7e-91 304.9 8.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 KND94487.1 - 0.09 12.6 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus PUF PF00806.14 KND94488.1 - 5.1e-57 186.2 10.6 3.3e-07 29.4 0.1 8.6 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat PUF PF00806.14 KND94489.1 - 3.3e-57 186.8 10.6 3.1e-07 29.4 0.1 8.6 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Rad51 PF08423.6 KND94490.1 - 6e-24 84.3 0.0 8.3e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KND94490.1 - 7.5e-13 48.3 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KND94490.1 - 1.4e-05 24.3 0.3 9.5e-05 21.5 0.2 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KND94490.1 - 0.0036 16.4 0.0 0.013 14.6 0.0 1.8 1 1 0 1 1 1 1 KaiC Speriolin_N PF15058.1 KND94490.1 - 0.029 14.2 2.1 0.051 13.4 1.5 1.4 1 0 0 1 1 1 0 Speriolin N terminus AAA_19 PF13245.1 KND94490.1 - 0.067 12.9 0.2 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Pept_tRNA_hydro PF01195.14 KND94490.1 - 0.083 12.3 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase DEAD PF00270.24 KND94491.1 - 1e-30 106.4 0.0 4.4e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KND94491.1 - 4e-18 65.0 0.0 8.8e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND94491.1 - 1.3e-07 31.6 0.2 4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KND94491.1 - 0.29 10.3 0.1 0.29 10.3 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF908 PF06012.7 KND94491.1 - 2 7.6 5.5 0.88 8.8 1.9 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) Tetraspannin PF00335.15 KND94492.1 - 7.5e-07 28.6 0.7 4.4e-06 26.1 0.5 1.9 1 1 0 1 1 1 1 Tetraspanin family YGGT PF02325.12 KND94492.1 - 0.0018 18.1 0.0 0.0067 16.3 0.0 1.9 1 0 0 1 1 1 1 YGGT family AzlD PF05437.7 KND94492.1 - 0.054 13.4 0.5 0.054 13.4 0.3 2.7 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DUF4203 PF13886.1 KND94492.1 - 1.9 7.8 9.5 0.15 11.4 3.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Glyco_hydro_72 PF03198.9 KND94493.1 - 1.3e-93 313.4 0.1 1.9e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KND94493.1 - 0.018 14.2 0.1 0.057 12.6 0.1 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Ras PF00071.17 KND94494.1 - 4.6e-51 172.4 0.0 1e-39 135.5 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KND94494.1 - 1.6e-17 64.0 0.0 3.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND94494.1 - 1.1e-11 44.2 0.0 3.9e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND94494.1 - 8.6e-08 31.8 0.0 9.8e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KND94494.1 - 9.7e-08 31.4 0.0 1.8e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND94494.1 - 6.4e-05 22.8 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KND94494.1 - 0.0068 15.9 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KND94494.1 - 0.011 15.8 0.1 0.097 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND94494.1 - 0.083 12.8 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KND94494.1 - 0.11 12.8 1.0 0.48 10.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 KND94494.1 - 0.11 11.8 0.2 13 5.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 KND94494.1 - 0.12 11.8 0.1 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain PMT PF02366.13 KND94495.1 - 2.4e-80 269.4 14.8 2.4e-80 269.4 10.3 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KND94495.1 - 1.2e-35 122.7 0.3 1.7e-35 122.2 0.2 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KND94495.1 - 2.3e-06 27.5 8.8 2.3e-06 27.5 6.1 3.1 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase VIT1 PF01988.14 KND94495.1 - 4.8 6.5 6.7 1.4 8.3 0.7 2.5 2 0 0 2 2 2 0 VIT family WW PF00397.21 KND94496.1 - 1.6e-06 27.8 4.9 3e-06 26.9 3.4 1.5 1 0 0 1 1 1 1 WW domain Choline_transpo PF04515.7 KND94497.1 - 3.8e-17 62.0 34.3 8.6e-15 54.2 12.7 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter Cys_Met_Meta_PP PF01053.15 KND94498.1 - 3.3e-149 496.3 0.0 3.7e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KND94498.1 - 1.2e-12 47.5 0.1 2e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KND94498.1 - 1.9e-08 33.6 0.0 3.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KND94498.1 - 2.2e-07 29.9 0.3 3.6e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KND94498.1 - 3.6e-07 29.6 0.0 6.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KND94498.1 - 0.0012 17.2 0.1 0.0015 16.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KND94498.1 - 0.035 12.5 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 KND94498.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein AMP-binding PF00501.23 KND94500.1 - 3.3e-82 276.1 0.0 4.1e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Exo_endo_phos_2 PF14529.1 KND94500.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MARVEL PF01284.18 KND94501.1 - 1.3e-17 63.9 12.5 1.6e-17 63.6 8.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain RHD3 PF05879.7 KND94502.1 - 0 1037.2 0.0 0 1037.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KND94502.1 - 2.2e-09 36.7 0.1 3.6e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KND94502.1 - 2.1e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KND94502.1 - 6.9e-05 22.7 0.1 0.00018 21.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KND94502.1 - 0.0003 20.7 0.0 0.00086 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KND94502.1 - 0.00073 20.0 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Cys_Met_Meta_PP PF01053.15 KND94502.1 - 0.017 13.4 0.2 0.026 12.7 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Septin PF00735.13 KND94502.1 - 0.049 12.6 0.1 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Septin Enkurin PF13864.1 KND94502.1 - 0.21 11.7 1.5 23 5.2 0.1 3.3 3 0 0 3 3 3 0 Calmodulin-binding HLH PF00010.21 KND94504.1 - 1.3e-08 34.3 0.1 5.8e-08 32.3 0.0 2.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.9 KND94504.1 - 4.7 5.1 14.6 7 4.5 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein GET2 PF08690.5 KND94505.1 - 2e-11 43.6 0.0 4.2e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 GET complex subunit GET2 WD40 PF00400.27 KND94507.1 - 1.9e-17 62.3 3.9 9.6e-05 22.1 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 KND94507.1 - 1.1e-09 38.2 0.0 4e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KND94507.1 - 2e-08 34.3 0.0 4.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 RRM_1 PF00076.17 KND94508.1 - 2.6e-17 62.2 0.0 3.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94508.1 - 8.7e-12 44.8 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND94508.1 - 8.5e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND94508.1 - 0.0033 17.1 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KND94508.1 - 0.046 13.4 0.0 0.077 12.7 0.0 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif B12D PF06522.6 KND94509.1 - 1.6e-06 27.7 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 KND94510.1 - 3.4e-18 65.4 4.6 3.9e-18 65.2 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KND94510.1 - 0.0028 16.9 0.4 0.0045 16.3 0.3 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Telomere_Sde2 PF13019.1 KND94511.1 - 1.1e-67 226.7 0.3 1.9e-67 226.0 0.2 1.4 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 KND94511.1 - 0.023 14.3 0.1 0.062 12.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family TP53IP5 PF15331.1 KND94511.1 - 4.6 7.0 10.5 1.6 8.5 5.2 1.7 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 S10_plectin PF03501.10 KND94512.1 - 1.5e-40 136.9 0.1 1.7e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.7 KND94513.1 - 5.8e-26 90.3 0.7 2e-25 88.6 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND94513.1 - 1.7e-17 63.2 0.0 2.8e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND94513.1 - 0.00017 22.5 0.0 0.00028 21.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KND94513.1 - 0.0025 16.9 0.1 0.004 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Saccharop_dh PF03435.13 KND94513.1 - 0.003 16.6 0.0 0.0037 16.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_18 PF12847.2 KND94513.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain XdhC_C PF13478.1 KND94513.1 - 0.02 15.2 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain DUF2338 PF10100.4 KND94513.1 - 0.079 11.3 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Gp_dh_N PF00044.19 KND94513.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KND94513.1 - 0.097 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND94513.1 - 0.099 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OB_NTP_bind PF07717.11 KND94514.1 - 7.2e-23 80.6 0.0 1.3e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KND94514.1 - 2.8e-21 75.4 0.1 6.1e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND94514.1 - 1.4e-12 47.2 0.0 3.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KND94514.1 - 0.00026 21.1 0.1 0.001 19.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KND94514.1 - 0.006 16.0 1.5 0.087 12.3 1.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KND94514.1 - 0.024 13.5 0.0 0.054 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KND94514.1 - 0.035 13.7 0.1 0.6 9.7 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KND94514.1 - 0.6 10.3 3.4 1.8 8.8 2.3 1.8 1 1 0 1 1 1 0 AAA domain SKG6 PF08693.5 KND94515.1 - 0.0025 17.1 3.0 0.0044 16.2 2.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3827 PF12877.2 KND94515.1 - 0.038 12.1 0.3 0.074 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) 7tm_1 PF00001.16 KND94515.1 - 0.29 10.2 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Shugoshin_C PF07557.6 KND94516.1 - 1.2e-11 43.8 5.5 1.2e-11 43.8 3.8 3.4 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 KND94516.1 - 3.5e-09 36.2 5.1 8e-09 35.0 3.5 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Mod_r PF07200.8 KND94516.1 - 0.058 13.3 1.1 0.15 12.0 0.8 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Metallophos_2 PF12850.2 KND94517.1 - 3.6e-12 46.4 0.0 4.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND94517.1 - 0.078 12.3 0.0 1.1 8.5 0.0 2.1 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase NUC173 PF08161.7 KND94518.1 - 3.1e-74 248.6 1.2 4.3e-73 244.8 0.1 2.9 3 0 0 3 3 3 1 NUC173 domain Rsbr_N PF08678.5 KND94518.1 - 0.062 13.1 0.0 8 6.3 0.0 3.2 3 0 0 3 3 3 0 Rsbr N terminal HEAT PF02985.17 KND94518.1 - 0.41 10.8 2.3 19 5.6 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat BUD22 PF09073.5 KND94518.1 - 8.3 5.3 19.7 2 7.3 11.2 1.7 2 0 0 2 2 2 0 BUD22 DUF2293 PF10056.4 KND94519.1 - 4.3e-27 93.9 0.1 1.2e-26 92.5 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Hydrolase_6 PF13344.1 KND94519.1 - 0.035 13.9 0.1 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SKG6 PF08693.5 KND94520.1 - 5e-07 28.9 4.0 1.3e-06 27.6 2.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KND94520.1 - 0.0026 17.4 0.1 0.0026 17.4 0.1 3.0 1 1 1 2 2 2 1 TMEM154 protein family DUF3301 PF11743.3 KND94520.1 - 0.033 13.7 0.1 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Herpes_gE PF02480.11 KND94520.1 - 0.033 12.4 0.1 0.033 12.4 0.1 2.0 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KND94520.1 - 0.038 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4381 PF14316.1 KND94520.1 - 0.062 13.4 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4366 PF14283.1 KND94520.1 - 0.075 12.4 0.6 0.35 10.2 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) CcmD PF04995.9 KND94520.1 - 0.079 12.7 1.1 0.13 11.9 0.7 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) COesterase PF00135.23 KND94521.1 - 1.8e-64 218.4 0.0 2.4e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KND94521.1 - 1.4e-08 34.6 4.6 6e-07 29.2 1.5 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND94521.1 - 0.0052 16.5 1.3 0.011 15.4 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DASH_Dad2 PF08654.5 KND94523.1 - 1.7e-34 117.8 0.5 2.8e-34 117.1 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 RasGEF PF00617.14 KND94524.1 - 8e-55 185.4 0.0 1.5e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KND94524.1 - 6.2e-18 64.8 0.0 1.8e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KND94524.1 - 5.2e-06 25.9 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND94524.1 - 5.9e-05 22.3 0.0 0.00012 21.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain ATP-grasp_2 PF08442.5 KND94526.1 - 1.6e-78 262.7 0.5 1.6e-78 262.7 0.4 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KND94526.1 - 1.5e-27 96.0 0.6 3.1e-27 95.0 0.4 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KND94526.1 - 1.1e-06 28.0 0.2 2.4e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KND94526.1 - 0.00031 20.3 1.9 0.0061 16.1 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KND94526.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain OKR_DC_1_N PF03709.10 KND94526.1 - 0.054 13.5 0.1 0.95 9.5 0.0 2.7 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain p450 PF00067.17 KND94527.1 - 1.8e-20 72.9 0.0 1.1e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Snf7 PF03357.16 KND94528.1 - 1.7e-34 118.6 9.1 2.3e-34 118.2 6.3 1.1 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KND94528.1 - 0.0024 17.3 0.1 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) DUF2203 PF09969.4 KND94528.1 - 0.92 9.7 6.1 2.5 8.3 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fructosamin_kin PF03881.9 KND94529.1 - 8.2e-67 225.1 0.0 2.2e-66 223.7 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KND94529.1 - 7e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1741 PF08427.5 KND94530.1 - 1.2e-85 286.7 0.1 2.3e-85 285.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DNA_binding_1 PF01035.15 KND94532.1 - 1.6e-24 85.4 0.0 3e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain EFG_II PF14492.1 KND94532.1 - 0.14 12.0 0.2 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Elongation Factor G, domain II Fe-S_biosyn PF01521.15 KND94533.1 - 1.6e-18 66.7 0.0 2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 KND94533.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) RR_TM4-6 PF06459.7 KND94533.1 - 0.13 12.1 1.0 0.17 11.7 0.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF726 PF05277.7 KND94534.1 - 9.4e-93 310.8 0.0 1.3e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) IMS PF00817.15 KND94535.1 - 2.2e-37 128.1 0.0 3.3e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KND94535.1 - 1.6e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PBP_like PF12727.2 KND94535.1 - 0.059 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain DUF974 PF06159.8 KND94536.1 - 7.4e-82 274.5 0.0 9.5e-82 274.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Gryzun PF07919.7 KND94536.1 - 0.076 11.3 0.0 0.16 10.2 0.0 1.5 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi DENN PF02141.16 KND94537.1 - 2.6e-48 164.1 0.1 5e-48 163.2 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KND94537.1 - 9.8e-18 63.9 0.1 1.8e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KND94537.1 - 4.6e-17 61.7 0.0 1.3e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 KND94537.1 - 0.00015 21.4 4.4 0.00029 20.5 3.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KND94537.1 - 0.0081 15.8 3.9 0.014 15.0 2.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 KND94537.1 - 0.012 15.3 5.2 0.031 13.9 3.6 1.8 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.6 KND94537.1 - 0.2 11.3 4.0 0.46 10.1 2.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_3 PF07649.7 KND94537.1 - 0.78 9.8 3.4 1.6 8.8 2.3 1.6 1 0 0 1 1 1 0 C1-like domain zf-RING_2 PF13639.1 KND94537.1 - 1.9 8.3 5.0 4.4 7.2 3.4 1.7 1 0 0 1 1 1 0 Ring finger domain DENN PF02141.16 KND94538.1 - 2.1e-52 177.5 0.1 3e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KND94538.1 - 3.5e-17 62.1 0.0 6e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 uDENN domain SPA PF08616.5 KND94538.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis ALS_ss_C PF10369.4 KND94539.1 - 3.8e-17 61.7 0.0 4.8e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KND94539.1 - 1.1e-11 43.9 0.1 2.1e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KND94539.1 - 6.4e-09 35.4 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain GTPase_Cys_C PF12631.2 KND94539.1 - 0.12 12.8 0.2 0.34 11.3 0.1 1.8 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE KH_3 PF13014.1 KND94540.1 - 4.7e-06 26.1 0.2 1.5e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 KH domain KH_1 PF00013.24 KND94540.1 - 1.3e-05 24.7 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF3712 PF12505.3 KND94541.1 - 2.7e-07 30.6 0.4 1e-05 25.5 0.2 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF3712) RskA PF10099.4 KND94541.1 - 0.046 13.4 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA OTCace_N PF02729.16 KND94542.1 - 9.2e-43 145.3 0.3 1.3e-42 144.7 0.2 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KND94542.1 - 1.3e-39 135.5 0.0 2.2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glyco_hydro_15 PF00723.16 KND94543.1 - 9.2e-96 321.1 0.0 1.2e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KND94543.1 - 1.2e-31 108.1 0.8 2.8e-31 106.9 0.6 1.7 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.8 KND94544.1 - 1.8e-148 495.6 60.7 2e-148 495.4 42.1 1.0 1 0 0 1 1 1 1 SART-1 family Pyridoxal_deC PF00282.14 KND94545.1 - 3.4e-70 236.3 0.0 4.4e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.16 KND94546.1 - 1.6e-92 309.9 0.0 2e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KND94546.1 - 4.9e-05 22.4 0.0 9.4e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 KND94547.1 - 1.1e-21 75.8 4.3 1.4e-08 34.3 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 KND94547.1 - 2.3e-08 33.8 3.7 2.3e-08 33.8 2.6 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KND94547.1 - 4.5e-06 25.7 0.0 2.2e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KND94547.1 - 0.0034 17.1 0.1 0.013 15.2 0.1 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ebola_NP PF05505.7 KND94547.1 - 0.23 9.5 3.1 0.29 9.1 0.0 2.0 2 0 0 2 2 2 0 Ebola nucleoprotein PQQ_3 PF13570.1 KND94547.1 - 1.6 9.0 5.6 28 5.1 0.0 4.2 3 1 0 3 3 3 0 PQQ-like domain WD40 PF00400.27 KND94548.1 - 1.4e-22 78.6 8.3 0.00015 21.5 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 KND94548.1 - 0.0027 17.2 0.4 1.4 8.2 0.0 2.3 1 1 0 2 2 2 2 PQQ-like domain DUF627 PF04781.7 KND94548.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Nup160 PF11715.3 KND94548.1 - 0.026 12.6 1.6 2.9 5.9 0.1 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ndc1_Nup PF09531.5 KND94549.1 - 3.1e-95 319.8 2.2 7.1e-55 186.5 4.4 2.2 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup DUF4129 PF13559.1 KND94550.1 - 0.00023 21.0 0.0 0.00065 19.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.6 KND94550.1 - 0.0016 17.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 NICE-3 protein DUF3673 PF12425.3 KND94550.1 - 0.18 11.6 1.9 0.38 10.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) HSF_DNA-bind PF00447.12 KND94552.1 - 4.7e-34 116.6 1.1 7e-34 116.1 0.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Med8 PF10232.4 KND94552.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Pyr_redox_2 PF07992.9 KND94553.1 - 5.7e-15 55.7 0.0 1.6e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND94553.1 - 5.1e-12 46.0 0.1 5.4e-09 36.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND94553.1 - 2.5e-07 30.9 0.7 0.00061 19.9 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND94553.1 - 1.6e-06 28.0 2.0 0.92 9.2 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 KND94553.1 - 8.8e-06 24.8 5.5 0.29 9.9 0.6 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KND94553.1 - 2.9e-05 23.1 0.3 0.072 11.9 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.1 KND94553.1 - 3.3e-05 22.9 0.2 0.00048 19.1 0.1 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KND94553.1 - 0.00031 20.7 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KND94553.1 - 0.0019 18.1 0.1 0.29 11.1 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain ThiF PF00899.16 KND94553.1 - 0.0068 16.2 0.2 0.17 11.6 0.1 2.5 2 0 0 2 2 2 1 ThiF family ApbA PF02558.11 KND94553.1 - 0.036 13.5 0.2 0.9 8.9 0.1 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 KND94553.1 - 0.059 12.0 1.2 7.9 4.9 0.2 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Zn_clus PF00172.13 KND94554.1 - 4.6e-10 39.2 10.7 9.7e-10 38.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND94554.1 - 1e-09 37.6 0.0 1.6e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3644 PF12358.3 KND94554.1 - 0.036 14.3 1.0 0.18 12.0 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) 60KD_IMP PF02096.15 KND94555.1 - 2.4e-10 40.3 0.0 3.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Syntaxin_2 PF14523.1 KND94556.1 - 1.3e-23 82.9 5.9 1.3e-23 82.9 4.1 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KND94556.1 - 1.8e-13 49.9 6.5 5.4e-13 48.4 4.5 1.9 1 0 0 1 1 1 1 SNARE domain DUF883 PF05957.8 KND94556.1 - 0.012 16.0 12.1 0.028 14.8 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF912 PF06024.7 KND94556.1 - 0.12 12.4 0.4 0.37 10.8 0.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF732 PF05305.9 KND94556.1 - 0.23 11.5 3.0 2.9 8.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF732) DUF4635 PF15466.1 KND94556.1 - 0.43 9.8 6.7 11 5.3 0.1 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4635) T2SF PF00482.18 KND94556.1 - 0.54 10.1 3.1 1.4 8.8 0.2 2.5 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1664 PF07889.7 KND94556.1 - 3.1 7.6 8.2 3.2 7.5 0.6 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) AMP-binding PF00501.23 KND94557.1 - 4.3e-89 298.7 0.1 5.3e-89 298.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND94557.1 - 7.7e-22 78.0 1.1 1.3e-19 70.8 0.5 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Rep_fac_C PF08542.6 KND94559.1 - 3.7e-23 81.2 0.1 1.8e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KND94559.1 - 9.2e-12 44.9 0.0 2.1e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KND94559.1 - 5.8e-07 29.7 0.1 1.3e-06 28.6 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND94559.1 - 4.1e-06 26.9 0.8 0.00017 21.7 0.1 2.7 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.1 KND94559.1 - 0.00012 22.1 2.5 0.029 14.3 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KND94559.1 - 0.00025 21.1 0.5 0.016 15.2 0.3 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF2861 PF11060.3 KND94559.1 - 0.012 14.9 0.1 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) ABC_tran PF00005.22 KND94559.1 - 0.021 15.1 0.2 0.041 14.1 0.1 1.8 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 KND94559.1 - 0.026 13.3 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 KND94559.1 - 0.028 14.1 0.2 0.071 12.7 0.1 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 KND94559.1 - 0.031 14.1 0.1 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.9 KND94559.1 - 0.044 12.3 0.1 0.1 11.1 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Bac_DnaA PF00308.13 KND94559.1 - 0.051 13.2 0.4 2.7 7.5 0.3 2.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_30 PF13604.1 KND94559.1 - 0.052 13.1 0.3 0.23 11.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KND94559.1 - 0.076 12.4 0.1 1.5 8.2 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain DNA_pol3_delta PF06144.8 KND94559.1 - 0.085 12.3 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_24 PF13479.1 KND94559.1 - 3.2 7.2 6.5 0.77 9.3 1.3 2.2 2 1 0 2 2 2 0 AAA domain PCI PF01399.22 KND94560.1 - 4.5e-20 71.9 0.1 2.3e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.4 KND94560.1 - 0.0001 21.7 1.6 0.00011 21.7 0.1 1.7 2 0 0 2 2 2 1 DDRGK domain TPR_8 PF13181.1 KND94560.1 - 0.00048 19.7 4.0 8.6 6.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KND94560.1 - 0.0035 17.0 2.0 0.63 9.9 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND94560.1 - 0.014 15.0 0.0 27 4.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KND94560.1 - 0.02 14.8 10.4 0.085 12.8 0.1 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KND94560.1 - 0.078 12.7 1.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 KND94560.1 - 0.14 12.1 7.0 11 6.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND94560.1 - 0.21 12.3 7.7 32 5.5 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KND94560.1 - 0.91 10.2 14.3 4.7 7.9 0.4 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND94560.1 - 1.4 9.5 6.4 8.6 7.0 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.22 KND94562.1 - 1.7e-50 168.7 2.2 2e-16 59.4 0.0 4.0 3 1 1 4 4 4 3 Mitochondrial carrier protein UcrQ PF02939.11 KND94562.1 - 0.00063 19.5 0.2 0.0019 17.9 0.1 1.8 1 0 0 1 1 1 1 UcrQ family Methyltransf_26 PF13659.1 KND94562.1 - 0.1 12.6 0.0 0.29 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Mak10 PF04112.8 KND94563.1 - 1.5e-49 167.4 0.0 2.9e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_L16 PF00252.13 KND94564.1 - 2.3e-28 98.5 0.9 3.1e-28 98.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 KND94565.1 - 2.1e-56 189.9 0.0 4.5e-56 188.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KND94565.1 - 2e-13 50.2 0.0 4.4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KND94565.1 - 3.1e-08 33.8 0.1 2.2e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND94565.1 - 0.00013 22.7 0.0 0.00013 22.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 KND94565.1 - 0.0002 21.4 0.0 0.0022 18.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND94565.1 - 0.0003 20.4 0.1 0.00081 19.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KND94565.1 - 0.00039 20.7 0.0 0.0018 18.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KND94565.1 - 0.0012 17.6 0.0 0.0022 16.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KND94565.1 - 0.0025 17.8 0.4 0.049 13.6 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KND94565.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KND94565.1 - 0.0078 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND94565.1 - 0.037 13.7 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KND94565.1 - 0.045 13.4 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 KND94565.1 - 0.067 12.9 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.7 KND94565.1 - 0.082 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus GrpE PF01025.14 KND94567.1 - 2e-50 170.5 3.9 2.6e-50 170.1 2.7 1.1 1 0 0 1 1 1 1 GrpE DHC_N2 PF08393.8 KND94567.1 - 0.0079 14.7 0.2 0.01 14.3 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Bap31 PF05529.7 KND94567.1 - 0.091 12.2 0.6 0.15 11.4 0.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Glyco_hydro_67C PF07477.7 KND94567.1 - 0.15 11.4 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus CN_hydrolase PF00795.17 KND94568.1 - 3.1e-19 69.0 0.0 6.7e-18 64.7 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase FAM101 PF15068.1 KND94568.1 - 0.11 11.9 0.4 0.18 11.2 0.3 1.3 1 0 0 1 1 1 0 FAM101 family Pro_racemase PF05544.6 KND94569.1 - 1.1e-124 415.5 0.0 1.2e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Peptidase_S28 PF05577.7 KND94570.1 - 3.8e-42 144.3 0.1 5.8e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Mito_carr PF00153.22 KND94571.1 - 2.3e-68 225.9 0.9 2.1e-23 81.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Steroid_dh PF02544.11 KND94572.1 - 4.2e-20 72.0 0.1 5.8e-14 52.1 0.1 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF544 PF04424.8 KND94572.1 - 5.4e-16 58.5 0.0 9.4e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF1295 PF06966.7 KND94572.1 - 0.0002 20.7 0.4 0.00037 19.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Lin-8 PF03353.10 KND94572.1 - 0.046 12.9 3.0 0.086 12.1 2.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1977 PF09320.6 KND94573.1 - 8.7e-22 77.3 0.0 1.5e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KND94573.1 - 1.1e-20 73.1 0.1 1.8e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S19 PF00203.16 KND94574.1 - 1.1e-23 82.6 0.0 1.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 KND94575.1 - 3.2e-26 90.9 0.5 4.7e-26 90.3 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KND94575.1 - 0.51 10.8 3.3 2.8 8.4 2.3 2.0 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 WLM PF08325.5 KND94577.1 - 1.5e-45 155.3 0.2 2.6e-45 154.5 0.0 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 KND94577.1 - 0.00053 19.8 0.5 0.0013 18.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KND94577.1 - 0.0011 18.6 1.0 0.0022 17.6 0.7 1.5 1 0 0 1 1 1 1 SprT-like family Telomere_Sde2 PF13019.1 KND94577.1 - 0.0021 17.7 3.0 0.22 11.1 0.0 3.2 3 0 0 3 3 3 1 Telomere stability and silencing YukD PF08817.5 KND94577.1 - 0.072 13.6 0.1 0.38 11.3 0.0 2.2 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.18 KND94577.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family OB_NTP_bind PF07717.11 KND94579.1 - 6.9e-27 93.5 0.0 1.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KND94579.1 - 2e-23 82.3 0.0 5.2e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND94579.1 - 9.9e-11 41.3 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KND94579.1 - 1.7e-07 31.4 0.0 4.9e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KND94579.1 - 1.7e-07 30.8 0.6 8.5e-07 28.6 0.3 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase SRP54 PF00448.17 KND94579.1 - 0.00012 21.6 0.2 0.00044 19.7 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 KND94579.1 - 0.0043 15.9 0.0 0.0085 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KND94579.1 - 0.005 17.0 1.1 0.052 13.7 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KND94579.1 - 0.0081 16.0 0.2 1.5 8.6 0.0 2.4 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KND94579.1 - 0.016 14.9 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Response_reg PF00072.19 KND94579.1 - 0.073 13.0 0.6 0.46 10.4 0.1 2.4 2 0 0 2 2 2 0 Response regulator receiver domain AAA_30 PF13604.1 KND94579.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_5 PF00266.14 KND94580.1 - 1.8e-22 79.5 0.0 2.4e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V B12-binding PF02310.14 KND94580.1 - 0.0011 18.8 0.2 0.0048 16.7 0.0 2.1 2 1 1 3 3 3 1 B12 binding domain RusA PF05866.6 KND94580.1 - 0.036 14.4 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA Ribonuc_L-PSP PF01042.16 KND94581.1 - 8.7e-15 54.5 0.0 1.1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2416 PF10315.4 KND94582.1 - 0.0047 17.1 0.6 0.04 14.1 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) Zn_clus PF00172.13 KND94583.1 - 2.1e-07 30.7 13.0 3.3e-07 30.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_pp38 PF04846.8 KND94585.1 - 0.042 13.1 0.1 0.17 11.2 0.1 2.1 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein adh_short PF00106.20 KND94587.1 - 1.2e-13 51.2 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KND94587.1 - 1.5e-07 31.6 0.1 1.1e-05 25.4 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KND94587.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND94587.1 - 4.6e-05 23.2 0.0 7.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KND94587.1 - 0.0083 15.5 0.0 0.025 14.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND94587.1 - 0.017 14.0 0.0 0.53 9.1 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein Fringe PF02434.11 KND94588.1 - 4.2e-08 32.7 0.0 7.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KND94588.1 - 0.0022 17.2 0.0 0.0072 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF604 tRNA-synt_1 PF00133.17 KND94591.1 - 1.5e-217 723.4 0.0 1.9e-217 723.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KND94591.1 - 2.4e-24 85.8 0.0 5.4e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KND94591.1 - 3e-18 65.6 0.0 1.5e-08 33.7 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KND94591.1 - 0.02 14.0 0.0 0.096 11.7 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain p12I PF12233.3 KND94592.1 - 0.5 10.6 3.8 0.13 12.5 0.6 1.5 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein SWIB PF02201.13 KND94593.1 - 5.1e-12 45.3 0.0 8.7e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Mo25 PF08569.6 KND94594.1 - 1.2e-119 399.3 0.1 1.3e-119 399.1 0.1 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 KND94594.1 - 0.091 12.5 0.2 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus CENP-B_dimeris PF09026.5 KND94595.1 - 0.019 15.1 6.0 0.04 14.1 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain APC_CDC26 PF10471.4 KND94595.1 - 0.079 13.7 2.6 0.093 13.4 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RXT2_N PF08595.6 KND94595.1 - 0.2 11.4 1.0 0.34 10.6 0.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 KND94595.1 - 1.9 6.3 6.8 2.2 6.0 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KND94595.1 - 3 7.3 8.1 5 6.6 5.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KND94595.1 - 6.9 5.8 8.9 11 5.2 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.20 KND94596.1 - 4e-68 229.3 0.0 5.1e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94596.1 - 7.2e-35 120.2 0.0 4.6e-34 117.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94596.1 - 0.00021 20.3 0.2 0.0064 15.4 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND94596.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND94596.1 - 0.0025 17.5 0.2 0.0079 15.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SNARE PF05739.14 KND94597.1 - 1.9e-11 43.4 1.6 4.3e-11 42.3 1.1 1.6 1 0 0 1 1 1 1 SNARE domain DUF812 PF05667.6 KND94597.1 - 0.0058 15.2 1.5 0.009 14.5 0.8 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF812) HXXSHH PF07586.6 KND94597.1 - 0.0078 15.1 4.3 0.014 14.3 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1552) DUF4407 PF14362.1 KND94597.1 - 0.0084 15.1 1.0 0.38 9.6 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) WXG100 PF06013.7 KND94597.1 - 0.1 12.6 5.3 1.6 8.7 0.0 3.3 2 2 1 3 3 3 0 Proteins of 100 residues with WXG GTPase_Cys_C PF12631.2 KND94597.1 - 0.14 12.5 1.0 1.7 9.1 0.0 2.7 2 1 1 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Phage_GP20 PF06810.6 KND94597.1 - 1.1 8.6 6.7 0.95 8.8 0.7 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 ADIP PF11559.3 KND94597.1 - 7.4 6.4 9.5 2 8.2 1.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sfi1 PF08457.5 KND94599.1 - 2e-16 59.5 61.4 9e-15 54.0 14.9 2.7 1 1 0 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.3 KND94600.1 - 4.9e-255 847.5 0.0 5.9e-255 847.3 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal PQQ_3 PF13570.1 KND94600.1 - 0.046 14.0 1.1 2.3 8.6 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 KND94600.1 - 0.34 10.8 0.0 0.34 10.8 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Mob1_phocein PF03637.12 KND94601.1 - 2.3e-69 232.5 0.0 3.2e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family HET PF06985.6 KND94602.1 - 3.1e-23 82.4 0.0 4.3e-20 72.2 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KND94602.1 - 8e-10 38.9 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND94602.1 - 4.1e-09 36.3 0.4 6e-07 29.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND94602.1 - 7.8e-08 32.6 0.1 5.9e-06 26.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KND94602.1 - 3e-05 23.5 0.1 0.38 10.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KND94602.1 - 0.0014 18.7 0.1 1.7 9.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_23 PF13489.1 KND94603.1 - 2.1e-11 43.8 0.0 8.9e-10 38.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND94603.1 - 6.4e-07 29.9 0.0 4e-06 27.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94603.1 - 6.4e-06 25.8 0.0 2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND94603.1 - 0.00015 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND94603.1 - 0.00028 21.3 0.0 0.00064 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KND94603.1 - 0.00079 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KND94603.1 - 0.009 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KND94603.1 - 0.061 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KND94603.1 - 0.077 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KND94603.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KND94603.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Skp1_POZ PF03931.10 KND94604.1 - 2.1e-10 40.5 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.8 KND94605.1 - 4e-49 166.2 0.1 9e-49 165.0 0.0 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KND94605.1 - 6e-10 38.8 0.2 1.1e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.24 KND94606.1 - 1.1e-13 51.5 0.0 1.9e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND94606.1 - 0.00012 22.0 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND94606.1 - 0.00076 19.6 0.2 0.0097 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KND94606.1 - 0.013 15.2 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KND94606.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KND94606.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KND94606.1 - 0.078 13.8 0.5 0.42 11.4 0.0 2.6 4 0 0 4 4 4 0 AAA domain Myb_DNA-binding PF00249.26 KND94607.1 - 1.4e-08 34.6 0.0 9.7e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Aldo_ket_red PF00248.16 KND94608.1 - 5.1e-20 71.4 0.0 6.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 KND94609.1 - 6.9e-47 158.8 0.0 9.1e-47 158.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND94609.1 - 2.8e-11 43.9 0.0 4.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND94609.1 - 8.6e-06 25.0 0.0 2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND94609.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.5 KND94610.1 - 7.5e-25 86.3 0.7 9.1e-25 86.1 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Glutaredoxin2_C PF04399.8 KND94610.1 - 0.056 13.0 0.1 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain MFS_1 PF07690.11 KND94612.1 - 4.5e-42 144.0 40.3 4.5e-42 144.0 27.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KND94612.1 - 2.3 8.0 8.7 0.24 11.2 2.3 2.4 2 0 0 2 2 2 0 MFS_1 like family Abhydrolase_3 PF07859.8 KND94613.1 - 4.6e-16 59.0 0.0 1.8e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND94613.1 - 9.5e-12 44.5 0.0 9e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KND94613.1 - 3e-07 30.3 0.1 5.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KND94613.1 - 8.8e-07 28.0 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KND94613.1 - 1.3e-06 28.5 2.3 2e-06 27.8 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KND94613.1 - 0.00017 21.0 0.2 0.0007 19.0 0.2 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KND94613.1 - 0.00092 18.7 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 KND94613.1 - 0.0024 16.7 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.13 KND94613.1 - 0.0059 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.4 KND94613.1 - 0.0066 15.7 0.0 0.077 12.2 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase p450 PF00067.17 KND94614.1 - 1.2e-30 106.4 0.0 7.3e-30 103.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 BPL_LplA_LipB PF03099.14 KND94615.1 - 2.4e-13 50.1 0.0 8.4e-13 48.4 0.0 2.0 3 0 0 3 3 3 1 Biotin/lipoate A/B protein ligase family p450 PF00067.17 KND94617.1 - 2.6e-42 144.9 0.0 3.3e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribonuclease PF00545.15 KND94618.1 - 2.6e-07 30.6 2.1 3.9e-07 30.0 1.5 1.4 1 1 0 1 1 1 1 ribonuclease Chorismate_synt PF01264.16 KND94619.1 - 1.1e-126 421.9 0.0 1.4e-126 421.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase HTH_psq PF05225.11 KND94619.1 - 0.038 13.5 0.1 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Fungal_trans PF04082.13 KND94620.1 - 1.4e-25 89.6 0.0 2.8e-24 85.4 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94620.1 - 5.4e-09 35.8 9.0 1e-08 34.9 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND94620.1 - 0.0087 14.6 0.1 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain POX PF07526.6 KND94620.1 - 0.081 13.1 0.6 0.42 10.8 0.0 2.3 3 0 0 3 3 3 0 Associated with HOX ADK PF00406.17 KND94621.1 - 1e-58 197.5 0.0 1.3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KND94621.1 - 1.9e-14 52.9 0.0 6.5e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KND94621.1 - 1e-06 29.5 0.0 2.2e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND94621.1 - 0.00054 19.8 0.0 0.0013 18.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND94621.1 - 0.0042 17.4 0.0 0.015 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KND94621.1 - 0.014 14.5 0.4 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin HOOK PF05622.7 KND94622.1 - 1.8e-09 36.0 51.5 1.8e-09 36.0 35.7 2.4 1 1 1 2 2 2 2 HOOK protein WEMBL PF05701.6 KND94622.1 - 0.00017 20.2 2.2 0.00017 20.2 1.6 4.1 1 1 2 4 4 4 1 Weak chloroplast movement under blue light CH PF00307.26 KND94622.1 - 0.0065 16.5 0.1 0.04 13.9 0.0 2.4 3 0 0 3 3 3 1 Calponin homology (CH) domain Alliinase_C PF04864.8 KND94622.1 - 0.011 14.3 0.0 0.021 13.4 0.0 1.4 1 0 0 1 1 1 0 Allinase DUF3015 PF11220.3 KND94622.1 - 0.079 12.5 0.3 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) DNA_pol_B_palm PF14792.1 KND94622.1 - 9.3 6.3 9.1 30 4.7 0.2 4.1 4 0 0 4 4 4 0 DNA polymerase beta palm DUF2183 PF09949.4 KND94623.1 - 2.5e-27 94.7 0.0 4.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF3073 PF11273.3 KND94624.1 - 2.4 8.7 4.7 1.1 9.8 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3073) Ribosomal_L28 PF00830.14 KND94625.1 - 7.4e-13 48.1 0.9 1.4e-12 47.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Trp_syntA PF00290.15 KND94626.1 - 5.3e-93 310.2 0.0 9.2e-93 309.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KND94626.1 - 9.8e-45 153.0 0.9 2e-44 152.0 0.7 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Baculo_PEP_C PF04513.7 KND94627.1 - 0.059 13.1 3.1 0.89 9.3 0.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg8 PF02991.11 KND94628.1 - 2.9e-50 168.5 0.2 4.2e-50 168.0 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KND94628.1 - 2.4e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 KND94629.1 - 1.4e-132 440.7 0.0 1.7e-132 440.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase MitMem_reg PF13012.1 KND94630.1 - 1.2e-38 131.6 0.0 3.2e-38 130.3 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KND94630.1 - 2.1e-28 98.3 0.4 3.9e-28 97.4 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Abhydrolase_3 PF07859.8 KND94630.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aminotran_1_2 PF00155.16 KND94631.1 - 7.5e-25 87.6 0.0 1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND94631.1 - 2.1e-07 29.5 0.1 3.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KND94631.1 - 0.00046 19.0 0.0 0.00065 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KND94631.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KND94631.1 - 0.0085 15.2 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 KND94631.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III ketoacyl-synt PF00109.21 KND94632.1 - 2.8e-61 207.2 1.1 4.2e-61 206.6 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KND94632.1 - 3.5e-60 203.6 0.0 5.3e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KND94632.1 - 3.5e-56 189.7 0.1 8e-56 188.5 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KND94632.1 - 2.3e-53 181.6 2.6 3.7e-53 180.9 1.8 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KND94632.1 - 3.4e-41 140.9 0.1 1.4e-40 138.9 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KND94632.1 - 6e-32 109.9 0.6 2e-31 108.3 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KND94632.1 - 1.3e-17 63.5 0.0 4e-17 61.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KND94632.1 - 5e-17 62.1 0.0 2.6e-16 59.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND94632.1 - 5.8e-11 42.3 0.0 5.1e-10 39.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94632.1 - 1.1e-09 38.0 0.0 3e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KND94632.1 - 2.6e-08 34.8 0.0 1.8e-07 32.1 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KND94632.1 - 5.3e-08 33.4 0.0 1.1e-06 29.1 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 KND94632.1 - 5.8e-07 29.2 0.1 1.6e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KND94632.1 - 1.3e-05 25.3 0.0 3.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KND94632.1 - 0.00029 21.2 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KND94632.1 - 0.00044 19.7 0.0 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase DREV PF05219.7 KND94632.1 - 0.16 10.8 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase P16-Arc PF04699.9 KND94634.1 - 1.2e-58 197.4 0.0 1.4e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.7 KND94635.1 - 9.4e-09 35.6 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND94635.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND94635.1 - 2.9e-07 30.8 0.0 5.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94635.1 - 0.00012 21.6 0.0 0.00038 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND94635.1 - 0.002 18.4 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND94635.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ala_racemase_N PF01168.15 KND94636.1 - 2.1e-38 132.0 0.0 2.5e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 KND94638.1 - 1.1e-123 413.4 5.5 1.3e-123 413.1 3.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KND94638.1 - 1.3e-44 150.7 0.0 3.9e-44 149.2 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KND94638.1 - 3.5e-19 69.2 0.0 7.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain AP4E_app_platf PF14807.1 KND94638.1 - 0.019 15.2 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform COG5 PF10392.4 KND94639.1 - 0.0022 17.9 1.0 0.0056 16.6 0.0 2.3 3 0 0 3 3 3 1 Golgi transport complex subunit 5 COG7 PF10191.4 KND94639.1 - 0.048 11.5 0.0 0.12 10.3 0.0 1.6 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) ATG16 PF08614.6 KND94639.1 - 0.14 11.9 6.3 1.6 8.4 0.6 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Amino_oxidase PF01593.19 KND94640.1 - 2.9e-20 72.7 0.2 1.5e-12 47.3 0.1 3.0 1 1 2 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND94640.1 - 7.9e-14 51.4 0.6 4.8e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND94640.1 - 1.3e-05 24.3 0.6 2.3e-05 23.4 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND94640.1 - 3e-05 23.0 0.3 6.2e-05 22.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KND94640.1 - 0.00011 22.5 0.8 0.00027 21.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND94640.1 - 0.00015 21.8 0.6 0.00022 21.3 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND94640.1 - 0.0008 18.5 0.2 0.0014 17.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KND94640.1 - 0.001 18.0 0.2 0.002 17.1 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KND94640.1 - 0.0011 18.1 0.1 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KND94640.1 - 0.0033 15.9 0.4 0.0064 15.0 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KND94640.1 - 0.028 14.3 0.1 0.06 13.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND94640.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KND94640.1 - 0.12 11.4 0.1 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KND94640.1 - 0.13 11.6 0.1 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 KND94640.1 - 0.15 11.9 1.6 8.9 6.1 0.1 2.4 2 1 0 2 2 2 0 short chain dehydrogenase RTA1 PF04479.8 KND94641.1 - 2.4e-44 151.5 4.6 2.9e-44 151.2 3.2 1.0 1 0 0 1 1 1 1 RTA1 like protein Dynamin_N PF00350.18 KND94642.1 - 1.4e-28 99.7 0.0 3.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KND94642.1 - 4.9e-15 55.0 0.0 1.9e-11 43.3 0.0 2.8 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 KND94642.1 - 4.6e-06 26.5 0.0 2.3e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND94642.1 - 0.0058 17.1 0.1 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KND94642.1 - 0.0092 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KND94642.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KND94642.1 - 0.042 13.1 0.0 5.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_23 PF13476.1 KND94642.1 - 0.11 12.8 0.1 0.77 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Choline_kinase PF01633.15 KND94644.1 - 0.063 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KND94644.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PPR_2 PF13041.1 KND94646.1 - 4.3e-15 55.4 0.9 8.5e-05 22.4 0.0 4.8 3 1 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 KND94646.1 - 1.6e-13 49.7 5.5 0.008 16.3 0.0 6.0 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.15 KND94646.1 - 3.3e-11 42.3 7.7 0.00036 20.2 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 KND94646.1 - 2.7 7.5 7.9 64 3.1 0.1 4.4 4 1 0 4 4 4 0 PPR repeat MRP-S25 PF13741.1 KND94647.1 - 2.4e-73 246.4 4.2 5.6e-71 238.6 2.9 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 KND94647.1 - 0.12 12.2 0.8 0.24 11.3 0.4 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 Alg14 PF08660.6 KND94648.1 - 1.1e-37 129.6 0.0 2e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ras PF00071.17 KND94648.1 - 0.015 14.7 0.0 2.3 7.5 0.0 2.5 2 1 1 3 3 3 0 Ras family DltD_N PF04915.7 KND94648.1 - 0.063 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 DltD N-terminal region IPK PF03770.11 KND94649.1 - 9.2e-52 175.5 0.0 1.4e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.2 KND94650.1 - 2.9e-24 84.2 34.0 6.6e-08 31.9 2.3 8.1 8 1 0 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND94650.1 - 1.7e-14 53.3 33.6 1.2e-05 24.9 1.4 7.3 3 1 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 KND94650.1 - 2.5e-07 29.7 26.5 0.59 10.3 0.2 10.4 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.1 KND94650.1 - 2.4e-05 23.9 21.6 0.98 9.6 0.0 9.7 10 1 0 10 10 10 1 Leucine Rich repeat LRR_7 PF13504.1 KND94650.1 - 0.0048 16.8 30.6 2.5 8.6 0.6 10.7 12 2 0 12 12 12 2 Leucine rich repeat LRR_9 PF14580.1 KND94650.1 - 0.43 10.1 13.2 5.3 6.5 0.1 4.6 3 1 2 5 5 5 0 Leucine-rich repeat DUF2012 PF09430.5 KND94652.1 - 6.3e-23 80.9 0.0 8.2e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF202 PF02656.10 KND94653.1 - 1e-24 86.4 3.7 1e-24 86.4 2.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2975 PF11188.3 KND94653.1 - 0.065 12.9 0.3 0.099 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Cytochrom_B_N PF00033.14 KND94653.1 - 0.14 11.4 3.3 0.24 10.7 2.3 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB AAA_11 PF13086.1 KND94654.1 - 8.2e-61 205.5 0.7 1.3e-60 204.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KND94654.1 - 1.4e-55 187.7 0.0 2.4e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND94654.1 - 5.3e-13 48.5 0.3 2.4e-12 46.4 0.0 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 KND94654.1 - 1e-11 44.8 0.0 8.2e-10 38.5 0.0 3.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KND94654.1 - 7.6e-07 28.8 0.0 0.43 10.0 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KND94654.1 - 9.1e-07 28.8 0.0 4.2e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KND94654.1 - 5.6e-06 25.5 0.1 2.3e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KND94654.1 - 1e-05 25.0 0.0 2.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KND94654.1 - 7.3e-05 22.3 0.1 0.00061 19.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND94654.1 - 0.0003 20.9 0.2 0.0054 16.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KND94654.1 - 0.00034 19.5 0.0 0.00062 18.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 KND94654.1 - 0.00095 18.6 0.0 0.015 14.6 0.0 2.7 2 1 0 3 3 3 1 AAA domain Helicase_RecD PF05127.9 KND94654.1 - 0.0012 18.5 0.0 0.023 14.3 0.0 2.4 1 1 0 1 1 1 1 Helicase Flavi_DEAD PF07652.9 KND94654.1 - 0.0028 17.4 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.4 KND94654.1 - 0.0029 16.3 0.0 0.005 15.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 KND94654.1 - 0.0039 16.4 0.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.1 KND94654.1 - 0.0057 16.1 0.8 9.1 5.6 0.0 3.3 3 1 0 3 3 3 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.2 KND94654.1 - 0.006 15.9 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction AAA_16 PF13191.1 KND94654.1 - 0.0067 16.4 0.1 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KND94654.1 - 0.01 15.3 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 KND94654.1 - 0.012 15.0 0.1 0.047 13.1 0.0 2.2 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AAA PF00004.24 KND94654.1 - 0.012 15.7 0.1 0.078 13.1 0.0 2.4 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KND94654.1 - 0.014 15.6 0.0 0.044 14.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KND94654.1 - 0.023 14.4 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KND94654.1 - 0.025 14.0 0.0 0.11 11.9 0.0 1.9 2 1 1 3 3 2 0 AAA-like domain NTPase_1 PF03266.10 KND94654.1 - 0.043 13.5 0.5 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 NTPase PIF1 PF05970.9 KND94654.1 - 0.077 11.9 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_17 PF13207.1 KND94654.1 - 0.34 11.7 2.2 1.2 10.0 0.6 2.7 2 1 0 2 2 2 0 AAA domain MbeD_MobD PF04899.7 KND94655.1 - 0.13 12.1 0.9 16 5.4 0.0 2.3 2 0 0 2 2 2 0 MbeD/MobD like Peptidase_M3 PF01432.15 KND94656.1 - 1.9e-119 399.7 0.0 2.6e-119 399.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KND94656.1 - 0.09 12.1 0.1 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Topoisom_I_N PF02919.10 KND94657.1 - 6.6e-91 303.3 4.2 6.6e-91 303.3 2.9 3.3 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KND94657.1 - 3.2e-86 288.2 7.2 3.2e-86 288.2 5.0 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KND94657.1 - 1.4e-30 104.7 0.2 5.7e-30 102.7 0.1 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KND94657.1 - 0.1 11.7 0.1 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family Glyco_hydro_16 PF00722.16 KND94658.1 - 3.1e-41 140.7 0.3 5.3e-41 139.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C2H2 PF00096.21 KND94659.1 - 1.2e-12 47.3 11.4 2.2e-06 27.6 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND94659.1 - 5.3e-10 38.9 11.3 0.00011 22.2 3.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND94659.1 - 2.7e-08 33.6 12.2 5.5e-07 29.5 3.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KND94659.1 - 9e-07 28.8 4.6 4e-05 23.6 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND94659.1 - 1.2e-06 28.4 5.4 0.00031 20.8 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND94659.1 - 0.0023 17.7 7.6 0.012 15.4 0.1 2.9 2 1 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 KND94659.1 - 0.9 9.3 7.2 0.74 9.6 1.6 2.4 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 KND94659.1 - 3.6 7.3 6.2 11 5.8 0.9 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 KND94659.1 - 4.1 7.1 7.8 5.7 6.7 1.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ATP_bind_4 PF01902.12 KND94660.1 - 3.6e-22 78.7 0.0 1e-07 31.5 0.0 4.0 4 0 0 4 4 4 3 ATP-binding region Ribonuc_L-PSP PF01042.16 KND94660.1 - 1.4e-11 44.1 0.0 8.6e-07 28.7 0.0 3.2 3 0 0 3 3 3 2 Endoribonuclease L-PSP Sec1 PF00995.18 KND94661.1 - 1.4e-132 443.2 0.0 1.8e-132 442.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.19 KND94661.1 - 2.8e-82 277.1 0.3 6.4e-82 276.0 0.2 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KND94661.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 KND94661.1 - 5e-08 33.1 1.8 5e-08 33.1 1.2 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND94661.1 - 7.6e-08 32.6 1.9 2.1e-07 31.2 1.4 1.7 1 0 0 1 1 1 1 HMG-box domain NAD_binding_8 PF13450.1 KND94661.1 - 1.2e-07 31.6 0.1 5.5e-07 29.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KND94661.1 - 0.0067 15.3 0.1 0.14 11.0 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase ATP-synt PF00231.14 KND94662.1 - 8.5e-72 241.9 5.8 9.8e-72 241.7 4.1 1.0 1 0 0 1 1 1 1 ATP synthase DUF4127 PF13552.1 KND94662.1 - 0.033 12.6 0.3 0.055 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Ribosomal_S3_C PF00189.15 KND94662.1 - 0.05 13.8 0.3 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain DUF1480 PF07351.8 KND94662.1 - 0.086 12.8 0.0 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1480) KAR9 PF08580.5 KND94664.1 - 1.1e-138 463.4 0.3 1.1e-138 463.4 0.2 1.9 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 KND94664.1 - 1 9.8 9.8 0.82 10.1 0.3 4.4 4 1 0 4 4 4 0 Syntaxin 6, N-terminal DEAD PF00270.24 KND94665.1 - 2.6e-20 72.5 0.0 6.6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND94665.1 - 3.2e-19 68.5 0.0 9.7e-17 60.6 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 KND94665.1 - 1.9e-11 43.5 0.1 4.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 KND94665.1 - 3.9e-06 26.8 0.0 0.00038 20.3 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KND94665.1 - 0.0063 15.8 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain HRDC PF00570.18 KND94665.1 - 0.008 15.8 1.1 0.028 14.1 0.0 2.5 3 0 0 3 3 3 1 HRDC domain DUF1275 PF06912.6 KND94666.1 - 2.9e-41 140.9 12.9 3.6e-41 140.6 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Hairy_orange PF07527.8 KND94666.1 - 0.014 15.1 0.0 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Hairy Orange DUF2975 PF11188.3 KND94666.1 - 0.14 11.8 0.7 8.7 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) 7tm_2 PF00002.19 KND94668.1 - 0.0004 19.5 8.8 0.0004 19.5 6.1 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) DC_STAMP PF07782.8 KND94668.1 - 0.22 11.1 3.5 2.5 7.6 0.2 2.5 1 1 1 2 2 2 0 DC-STAMP-like protein Pox_A14 PF05767.7 KND94668.1 - 2.8 7.9 9.7 0.83 9.6 0.3 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Cellulase PF00150.13 KND94669.1 - 5.4e-34 117.6 0.0 6.6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.5 KND94670.1 - 5.5e-21 74.2 0.0 3.1e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 CRT10 Ammonium_transp PF00909.16 KND94672.1 - 5.4e-118 393.9 30.5 6.2e-118 393.7 21.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 KND94672.1 - 3.8 7.3 9.7 12 5.7 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) ECH PF00378.15 KND94673.1 - 5.1e-68 228.8 0.2 6.5e-68 228.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KND94673.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 MotA_activ PF09114.5 KND94673.1 - 0.053 13.2 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain PALP PF00291.20 KND94675.1 - 1.2e-58 198.7 0.1 1.7e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.20 KND94675.1 - 2.1e-06 27.3 1.4 2.1e-06 27.3 1.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND94675.1 - 6.5e-06 25.8 2.5 6.5e-06 25.8 1.7 2.7 3 0 0 3 3 3 1 Ring finger domain SH3_9 PF14604.1 KND94675.1 - 1.2e-05 24.8 0.1 2.5e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND94675.1 - 1.3e-05 24.5 0.0 2.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_2 PF13923.1 KND94675.1 - 6.7e-05 22.8 1.4 6.7e-05 22.8 1.0 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND94675.1 - 0.00073 19.2 1.5 0.00073 19.2 1.0 3.2 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND94675.1 - 0.0092 15.8 3.7 0.0092 15.8 2.6 2.4 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND94675.1 - 0.014 15.1 0.2 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KND94675.1 - 0.021 14.4 0.7 0.021 14.4 0.5 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 KND94675.1 - 0.075 12.5 11.5 2 8.0 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, ZZ type zf-RING_6 PF14835.1 KND94675.1 - 0.096 12.4 0.1 0.096 12.4 0.1 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Fer2_BFD PF04324.10 KND94676.1 - 0.041 13.9 0.1 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Proteasome PF00227.21 KND94677.1 - 1.3e-40 138.7 0.5 7.6e-38 129.6 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Pr_beta_C PF12465.3 KND94677.1 - 5.5e-12 44.7 0.1 1.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Ribosomal_L19 PF01245.15 KND94678.1 - 2.5e-16 59.4 0.0 4.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 DUF1843 PF08898.5 KND94678.1 - 0.11 12.5 0.4 0.26 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Sel1 PF08238.7 KND94679.1 - 5.2e-14 52.3 10.0 0.0012 19.3 0.7 4.5 4 0 0 4 4 4 4 Sel1 repeat Anillin PF08174.6 KND94680.1 - 7e-31 107.1 0.4 2e-30 105.6 0.1 2.0 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 KND94680.1 - 3.4e-09 36.8 0.0 9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 PH domain RNA_pol_A_bac PF01000.21 KND94681.1 - 6.2e-26 90.7 0.0 1.3e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KND94681.1 - 4.7e-15 54.4 0.0 6e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KND94682.1 - 0.025 14.4 0.5 0.069 13.0 0.1 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat STE PF02200.11 KND94683.1 - 2e-61 204.9 0.7 3.5e-61 204.1 0.2 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 KND94683.1 - 0.00028 21.0 3.8 0.00074 19.7 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND94683.1 - 0.0012 19.0 2.9 0.0028 17.8 2.0 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger CorA PF01544.13 KND94684.1 - 1.1e-38 132.9 0.8 6.9e-38 130.3 0.5 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1900 PF08954.6 KND94685.1 - 1.1e-48 164.2 0.0 3.5e-47 159.3 0.0 2.7 2 1 0 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KND94685.1 - 5.5e-34 115.6 0.0 1.1e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KND94685.1 - 2.1e-25 87.6 2.0 9e-08 31.7 0.0 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KND94685.1 - 0.00013 20.2 0.1 0.17 9.9 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 CBF PF03914.12 KND94686.1 - 7.8e-47 158.7 1.3 2.2e-46 157.2 0.4 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Utp12 PF04003.7 KND94686.1 - 0.0044 16.9 0.4 0.012 15.4 0.3 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family COPIIcoated_ERV PF07970.7 KND94687.1 - 3.6e-72 242.6 0.0 5.7e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KND94687.1 - 2.8e-34 116.9 0.0 5.7e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.1 KND94688.1 - 1.5e-29 101.9 2.8 1.5e-29 101.8 0.6 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KND94688.1 - 3.9e-21 74.4 0.0 5.8e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94688.1 - 8.4e-17 60.9 0.0 1.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KND94688.1 - 3.3e-10 39.0 2.8 3.3e-10 39.0 1.9 2.6 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KND94688.1 - 2.5e-08 33.6 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KND94688.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 Telomere_reg-2 PF10193.4 KND94689.1 - 3e-37 127.3 0.0 1.6e-36 125.0 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.16 KND94690.1 - 4.7e-31 107.4 0.4 4.7e-23 81.5 0.0 2.9 3 0 0 3 3 3 2 ThiF family E2_bind PF08825.5 KND94690.1 - 8e-28 96.0 0.1 1.6e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KND94690.1 - 1.2e-24 85.6 0.7 2.3e-24 84.7 0.5 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KND94690.1 - 4.5e-14 51.5 2.2 4.5e-14 51.5 1.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KND94690.1 - 0.026 14.6 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MoeZ_MoeB PF05237.8 KND94690.1 - 0.084 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain NAD_binding_9 PF13454.1 KND94690.1 - 0.16 11.7 0.5 0.59 9.8 0.0 2.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pkinase PF00069.20 KND94691.1 - 4e-63 212.9 0.0 5.3e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94691.1 - 1.8e-27 96.0 0.0 2.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94691.1 - 0.0038 16.2 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND94691.1 - 0.032 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND94691.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TIR_2 PF13676.1 KND94692.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 TIR domain EST1_DNA_bind PF10373.4 KND94693.1 - 4.3e-46 157.3 2.7 5.7e-46 156.9 0.9 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KND94693.1 - 6.5e-21 74.6 0.1 1.4e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 HTH_16 PF12645.2 KND94693.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PfkB PF00294.19 KND94694.1 - 1.9e-65 220.9 0.0 2.2e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KND94694.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase G10 PF01125.12 KND94695.1 - 9.5e-60 200.3 2.6 1.1e-59 200.2 1.8 1.0 1 0 0 1 1 1 1 G10 protein Ribosomal_L10 PF00466.15 KND94697.1 - 8e-20 70.6 0.0 1.2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 KND94698.1 - 1.2e-29 102.4 2.1 2.1e-29 101.6 1.4 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KND94698.1 - 3.6e-16 58.5 0.1 1.8e-15 56.3 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94698.1 - 9.6e-13 47.9 0.1 1.7e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND94698.1 - 1.9e-08 34.0 0.2 4.5e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 KND94699.1 - 7.2e-14 51.2 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.13 KND94700.1 - 1.4e-85 286.2 0.2 1.6e-85 286.0 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Toprim PF01751.17 KND94700.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Toprim domain zf-C2H2_4 PF13894.1 KND94701.1 - 0.0064 16.7 8.3 0.13 12.6 0.0 3.0 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KND94701.1 - 0.0074 16.5 2.1 2.3 8.7 0.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type TFIIA PF03153.8 KND94701.1 - 8 6.2 8.7 19 5.0 1.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.13 KND94703.1 - 0.00029 20.6 13.0 0.00051 19.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF543 PF04418.7 KND94705.1 - 9.5e-29 99.1 0.0 1.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 KND94706.1 - 2.5e-50 171.1 0.9 5e-50 170.1 0.3 1.8 2 0 0 2 2 2 1 Urb2/Npa2 family Abhydrolase_6 PF12697.2 KND94707.1 - 3.9e-06 26.8 0.9 9.9e-06 25.5 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Phostensin_N PF13916.1 KND94707.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Abhydrolase_5 PF12695.2 KND94707.1 - 0.09 12.5 0.1 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family adh_short PF00106.20 KND94708.1 - 9.5e-21 74.4 0.0 1.3e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND94708.1 - 1.3e-07 31.5 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND94708.1 - 2.3e-06 27.5 0.0 3.9e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KND94708.1 - 0.00022 20.7 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KND94708.1 - 0.00043 20.6 0.3 0.00082 19.7 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KND94708.1 - 0.00079 19.5 0.1 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KND94708.1 - 0.0043 17.0 0.1 0.0074 16.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KND94708.1 - 0.005 15.7 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KND94708.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 KND94708.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 KND94710.1 - 8.3e-27 93.9 0.0 4.8e-25 88.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94710.1 - 4.9e-05 22.5 0.1 0.054 12.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase GST_N_2 PF13409.1 KND94711.1 - 1e-23 83.0 0.0 2.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KND94711.1 - 2.2e-18 65.8 0.1 7.5e-18 64.1 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KND94711.1 - 1.3e-09 37.9 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND94711.1 - 2.3e-07 31.1 0.1 4.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KND94711.1 - 5.1e-06 26.6 0.1 5e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-LYAR PF08790.6 KND94712.1 - 1.9e-08 33.8 0.8 4.4e-08 32.6 0.5 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DUF3512 PF12024.3 KND94712.1 - 0.035 13.4 0.5 0.035 13.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) Pex2_Pex12 PF04757.9 KND94713.1 - 6.4e-40 136.9 3.5 8.2e-40 136.6 2.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KND94713.1 - 1.1e-12 47.5 8.0 1.7e-12 46.9 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND94713.1 - 2.9e-12 46.3 7.6 4.5e-12 45.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND94713.1 - 4.7e-10 38.9 6.5 7.1e-10 38.3 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND94713.1 - 4.8e-10 38.9 6.1 7.5e-10 38.3 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND94713.1 - 1.4e-08 34.2 5.5 2.2e-08 33.6 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND94713.1 - 8.1e-07 28.8 7.7 1.3e-06 28.1 5.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KND94713.1 - 2.6e-05 23.9 2.4 5.4e-05 22.9 1.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KND94713.1 - 6.1e-05 23.0 6.8 0.00013 21.9 4.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KND94713.1 - 0.00016 21.3 4.1 0.00033 20.2 2.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KND94713.1 - 0.0022 17.4 1.3 0.004 16.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KND94713.1 - 0.02 14.7 2.6 0.035 13.9 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KND94713.1 - 0.052 13.1 8.4 0.098 12.2 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF687 PF05095.7 KND94713.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) TerY-C PF15616.1 KND94713.1 - 0.18 11.7 3.1 0.31 10.9 2.1 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 KND94713.1 - 2.2 8.2 7.8 6.8 6.6 5.4 1.7 1 1 0 1 1 1 0 IBR domain R3H PF01424.17 KND94714.1 - 1.9e-12 46.6 0.0 3.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KND94714.1 - 0.0039 17.1 16.2 0.0039 17.1 11.2 11.8 13 1 0 13 13 13 5 NF-X1 type zinc finger Abhydrolase_5 PF12695.2 KND94715.1 - 9.6e-15 54.5 0.0 4.4e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND94715.1 - 1.4e-10 41.4 0.0 1.1e-08 35.2 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND94715.1 - 2e-05 23.8 0.0 0.00024 20.4 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KND94715.1 - 2.7e-05 23.6 0.0 0.021 14.2 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 KND94715.1 - 0.0002 20.8 0.0 0.00059 19.3 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KND94715.1 - 0.0005 19.6 0.0 0.88 9.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 KND94715.1 - 0.0025 16.3 0.0 0.91 7.9 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 KND94715.1 - 0.006 15.8 0.0 3.6 6.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 KND94715.1 - 0.064 12.8 0.4 0.9 9.0 0.1 2.5 1 1 2 3 3 3 0 PGAP1-like protein Abhydrolase_3 PF07859.8 KND94715.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold WSC PF01822.14 KND94716.1 - 1.8e-71 236.0 69.2 8.5e-20 70.4 8.9 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 KND94716.1 - 1.6e-28 99.4 0.0 2.2e-27 95.6 0.0 2.7 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KND94716.1 - 1e-22 80.0 0.0 1.8e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) MPC PF03650.8 KND94718.1 - 4.8e-36 123.3 0.0 5.9e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) EutH PF04346.7 KND94718.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH COesterase PF00135.23 KND94719.1 - 0.0046 15.7 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF896 PF05979.7 KND94720.1 - 0.52 9.9 2.8 0.9 9.1 2.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) CPSase_L_D2 PF02786.12 KND94721.1 - 5.5e-81 270.8 0.3 9.2e-81 270.1 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KND94721.1 - 3.5e-66 222.3 0.0 6.1e-66 221.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KND94721.1 - 6.1e-35 119.6 0.0 1.2e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KND94721.1 - 4.7e-31 106.9 0.0 1.9e-30 104.9 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KND94721.1 - 6e-26 91.5 0.0 1.2e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KND94721.1 - 3.3e-20 72.6 0.1 6.2e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KND94721.1 - 3.6e-19 68.1 1.0 1e-18 66.7 0.7 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KND94721.1 - 4.7e-15 55.1 0.0 2.3e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KND94721.1 - 3.7e-12 45.7 0.5 5.1e-07 29.2 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KND94721.1 - 8.2e-11 41.6 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KND94721.1 - 6.6e-08 32.1 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KND94721.1 - 6e-07 29.1 0.0 2.4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 KND94721.1 - 2.6e-05 23.6 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 KND94721.1 - 2.6e-05 23.5 0.0 0.081 12.0 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KND94721.1 - 6.5e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KND94721.1 - 0.00015 22.0 0.1 0.012 15.9 0.0 3.2 2 1 1 3 3 3 2 HlyD family secretion protein DUF2118 PF09891.4 KND94721.1 - 0.007 16.0 0.5 0.023 14.3 0.0 2.1 2 0 0 2 2 1 1 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.6 KND94721.1 - 0.014 14.5 0.1 0.027 13.6 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.14 KND94721.1 - 0.019 14.5 0.0 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 KND94721.1 - 0.046 13.4 0.5 0.14 11.9 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Rieske PF00355.21 KND94721.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Metallophos PF00149.23 KND94722.1 - 8.7e-44 149.3 0.2 8.7e-44 149.3 0.1 1.9 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Catalase PF00199.14 KND94723.1 - 3.8e-184 611.7 2.3 4.7e-184 611.4 1.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KND94723.1 - 3.5e-12 45.9 0.5 9.3e-12 44.6 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive zf-CCCH PF00642.19 KND94725.1 - 1.7e-08 33.9 18.1 4.6e-07 29.3 1.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KND94725.1 - 5.8e-07 29.2 0.0 9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND94725.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94725.1 - 0.0081 16.1 0.0 0.024 14.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 KND94725.1 - 3.5 7.4 9.0 0.4 10.4 1.3 2.8 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B Oxysterol_BP PF01237.13 KND94726.1 - 1.4e-72 244.1 0.0 1.7e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Peptidase_S8 PF00082.17 KND94727.1 - 1.6e-47 162.0 2.1 2.1e-47 161.6 1.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND94727.1 - 1.6e-15 57.3 0.1 3.7e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-GRF PF06839.7 KND94728.1 - 2.9e-06 27.1 6.4 5.4e-06 26.2 4.4 1.5 1 0 0 1 1 1 1 GRF zinc finger zf-C4_Topoisom PF01396.14 KND94728.1 - 0.0053 16.2 0.4 0.0096 15.4 0.3 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger TMF_DNA_bd PF12329.3 KND94728.1 - 0.018 14.8 2.5 0.03 14.1 1.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 KND94728.1 - 0.085 12.6 1.4 0.13 12.0 0.9 1.2 1 0 0 1 1 1 0 Prefoldin subunit DnaJ PF00226.26 KND94729.1 - 2.4e-12 46.3 1.5 7.1e-12 44.8 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain Motilin_ghrelin PF04644.7 KND94729.1 - 0.22 11.3 3.1 0.68 9.7 2.2 1.8 1 0 0 1 1 1 0 Motilin/ghrelin DUF2235 PF09994.4 KND94731.1 - 8.6e-55 186.0 0.0 2.3e-36 125.5 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KND94731.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3605 PF12239.3 KND94733.1 - 1.1e-55 187.8 0.1 1.3e-55 187.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.13 KND94734.1 - 9.2e-11 41.9 0.0 1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 KND94735.1 - 3.1e-58 196.9 0.0 4.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94735.1 - 1.5e-42 145.5 0.0 2e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94735.1 - 0.00032 19.7 0.0 0.0079 15.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND94735.1 - 0.077 12.7 0.0 0.41 10.3 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KND94735.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 KND94737.1 - 7.2e-53 179.2 0.0 8.8e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRF PF01765.14 KND94737.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor HRDC PF00570.18 KND94737.1 - 0.077 12.7 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 HRDC domain DRMBL PF07522.9 KND94738.1 - 1.1e-33 115.4 0.0 2.3e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KND94738.1 - 2e-11 43.7 0.0 6.6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TIP49 PF06068.8 KND94738.1 - 0.34 9.5 0.1 0.54 8.9 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Cut8_N PF14482.1 KND94738.1 - 0.98 9.4 7.3 0.17 11.8 1.9 2.3 1 1 1 2 2 2 0 Cut8 proteasome-binding domain DUF4611 PF15387.1 KND94738.1 - 4.5 7.4 7.7 0.3 11.2 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) AMP-binding PF00501.23 KND94739.1 - 8.5e-68 228.6 0.0 1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND94739.1 - 3.3e-17 63.1 0.1 6.4e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_Mu_Gp45 PF06890.7 KND94739.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein LSM PF01423.17 KND94740.1 - 2.5e-16 58.9 0.5 3.7e-16 58.4 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND94740.1 - 0.015 15.2 0.0 0.018 14.9 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 KND94740.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.5 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) WD40 PF00400.27 KND94741.1 - 1.4e-71 234.0 24.3 6.3e-10 38.5 0.1 12.6 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 KND94741.1 - 2.5e-19 69.1 0.5 4.2e-19 68.4 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KND94741.1 - 0.00058 18.1 9.2 0.027 12.6 0.3 4.9 2 2 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KND94741.1 - 0.0066 16.1 0.1 0.16 11.6 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KND94741.1 - 0.058 12.1 8.0 6 5.5 0.1 4.8 2 1 2 6 6 6 0 Nup133 N terminal like P34-Arc PF04045.9 KND94742.1 - 1.7e-99 332.0 0.7 2.1e-99 331.7 0.5 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Protamine_3 PF08188.6 KND94742.1 - 0.15 12.0 1.5 0.29 11.1 1.1 1.5 1 0 0 1 1 1 0 Spermatozal protamine family Helicase_C_3 PF13625.1 KND94743.1 - 7.5e-27 93.6 0.0 2.4e-25 88.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND94743.1 - 1.4e-13 51.0 0.0 3.5e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KND94743.1 - 4.9e-10 39.1 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KND94743.1 - 7.9e-09 34.7 0.0 1.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Biotin_lipoyl_2 PF13533.1 KND94743.1 - 0.068 12.8 0.7 0.19 11.4 0.5 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like SNase PF00565.12 KND94744.1 - 2.5e-26 92.0 0.0 3.5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue zf-CHY PF05495.7 KND94745.1 - 1.3e-13 50.9 19.3 1.7e-13 50.5 13.4 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KND94745.1 - 0.11 12.3 10.6 3.4 7.5 5.2 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3797 PF12677.2 KND94745.1 - 0.7 9.5 0.0 0.7 9.5 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Cytochrome_C7 PF14522.1 KND94745.1 - 0.83 9.3 14.7 1.3 8.6 10.2 1.4 1 0 0 1 1 1 0 Cytochrome c7 Evr1_Alr PF04777.8 KND94745.1 - 2.1 8.3 12.9 22 5.0 8.9 2.7 1 1 0 1 1 1 0 Erv1 / Alr family HypA PF01155.14 KND94745.1 - 2.4 7.8 11.3 2.3 7.9 5.8 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 KND94745.1 - 3.1 7.8 17.4 2.2 8.3 6.1 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain zf-RING_3 PF14369.1 KND94745.1 - 4.4 7.3 13.7 0.85 9.6 4.9 2.8 1 1 2 3 3 3 0 zinc-finger Rax2 PF12768.2 KND94746.1 - 5.5e-90 301.3 14.1 1e-83 280.7 0.0 5.0 5 1 0 5 5 5 4 Cortical protein marker for cell polarity stn_TNFRSF12A PF12191.3 KND94746.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RicinB_lectin_2 PF14200.1 KND94746.1 - 0.073 13.4 0.2 2.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like TrkH PF02386.11 KND94747.1 - 4.4e-109 364.2 6.5 4.4e-109 364.2 4.5 2.0 2 0 0 2 2 2 2 Cation transport protein CH PF00307.26 KND94748.1 - 2.5e-39 133.6 0.3 1e-19 70.5 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KND94748.1 - 2.3e-28 97.9 1.8 1.9e-27 95.0 0.1 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KND94748.1 - 2.5e-13 49.4 0.3 2.4e-08 33.5 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KND94748.1 - 8.8e-06 25.1 0.5 0.00085 19.0 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KND94748.1 - 0.00075 19.0 1.3 0.062 12.9 0.1 3.4 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KND94748.1 - 0.0018 17.4 0.2 0.087 12.1 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KND94748.1 - 0.0022 18.1 1.4 0.016 15.3 0.9 2.6 1 0 0 1 1 1 1 EF-hand domain pair Spectrin PF00435.16 KND94748.1 - 0.0027 17.9 1.6 1.1 9.6 0.2 2.6 2 0 0 2 2 2 2 Spectrin repeat EF-hand_like PF09279.6 KND94748.1 - 0.039 13.9 0.1 0.15 12.0 0.0 2.1 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Ribonuc_2-5A PF06479.7 KND94748.1 - 0.043 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease 2-5A Sipho_Gp157 PF05565.6 KND94748.1 - 0.46 10.0 3.2 0.51 9.9 0.2 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Proteasome PF00227.21 KND94750.1 - 1.3e-53 181.1 0.1 1.8e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KND94750.1 - 2.2e-05 23.6 0.1 2.2e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.14 KND94751.1 - 2.8e-53 180.7 0.0 4.3e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KND94751.1 - 1.5e-34 118.4 0.5 2.8e-34 117.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 KND94751.1 - 0.36 10.7 16.1 0.25 11.2 4.6 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.14 KND94752.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF1682 PF07946.9 KND94753.1 - 1.2e-96 323.3 0.0 1.4e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.3 KND94753.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Saccharop_dh PF03435.13 KND94754.1 - 7.3e-21 74.5 0.0 1.3e-20 73.7 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KND94754.1 - 0.0031 17.7 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KND94754.1 - 0.036 13.4 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KND94754.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KND94754.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KND94754.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Ribosomal_L37ae PF01780.14 KND94755.1 - 8e-39 131.4 9.6 1.1e-38 130.9 6.7 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KND94755.1 - 0.0003 20.5 3.9 0.0005 19.8 2.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KND94755.1 - 0.0096 15.3 4.6 0.035 13.5 0.1 2.4 2 0 0 2 2 2 1 A2L zinc ribbon domain Sgf11 PF08209.6 KND94755.1 - 0.019 14.2 0.8 0.083 12.2 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Thymidylat_synt PF00303.14 KND94755.1 - 0.042 12.8 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase Zn-ribbon_8 PF09723.5 KND94755.1 - 0.17 11.8 1.2 0.7 9.8 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KND94755.1 - 0.2 11.3 1.9 0.35 10.5 1.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-BED PF02892.10 KND94755.1 - 0.65 9.8 6.6 1.1 9.0 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 KND94755.1 - 4 7.9 7.4 1 9.7 0.7 2.5 1 1 1 2 2 2 0 Zinc-finger double domain DUF155 PF02582.9 KND94756.1 - 7.3e-56 188.8 0.4 9.9e-56 188.3 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Glyoxalase_2 PF12681.2 KND94756.1 - 1.6e-11 44.7 0.1 4.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain Ank_2 PF12796.2 KND94757.1 - 1.3e-117 384.4 6.0 2.6e-15 56.5 0.0 9.9 2 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KND94757.1 - 2.8e-92 298.2 21.0 8.8e-06 25.2 0.0 19.2 19 0 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 KND94757.1 - 5.7e-86 281.5 15.6 2.3e-09 37.5 0.0 13.2 5 4 9 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND94757.1 - 6.9e-79 251.8 0.1 0.00071 19.5 0.0 19.3 19 0 0 19 19 19 17 Ankyrin repeat Ank_5 PF13857.1 KND94757.1 - 5.2e-74 242.6 25.5 3.3e-10 39.8 0.0 14.8 3 3 12 16 16 16 15 Ankyrin repeats (many copies) F-box-like PF12937.2 KND94757.1 - 0.0037 16.9 0.1 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF937 PF06078.6 KND94757.1 - 0.015 15.5 10.7 4.8 7.4 0.0 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF937) SMC_N PF02463.14 KND94758.1 - 6.7e-63 211.8 2.6 1.2e-62 211.0 1.8 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain CAF1 PF04857.15 KND94758.1 - 1.3e-44 152.4 0.0 5.2e-44 150.5 0.0 2.1 1 0 0 1 1 1 1 CAF1 family ribonuclease SMC_hinge PF06470.8 KND94758.1 - 3e-27 94.9 0.0 3.2e-26 91.6 0.0 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KND94758.1 - 9.7e-14 52.1 18.8 9.7e-14 52.1 13.0 6.8 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 KND94758.1 - 1.7e-13 51.1 1.2 1.8e-05 24.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KND94758.1 - 0.00044 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KND94758.1 - 0.0096 15.1 18.2 0.14 11.2 0.0 4.7 3 1 0 4 4 4 2 Reovirus sigma C capsid protein ABC_tran PF00005.22 KND94758.1 - 0.7 10.1 0.0 0.7 10.1 0.0 5.9 3 2 0 3 3 3 0 ABC transporter AAA_27 PF13514.1 KND94758.1 - 1.9 6.0 102.9 0.24 9.0 24.8 3.3 2 1 1 3 3 3 0 AAA domain DUF3535 PF12054.3 KND94759.1 - 1.2e-137 459.1 4.6 3.3e-137 457.7 1.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KND94759.1 - 1.2e-73 247.4 0.0 1.9e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDC37_N PF03234.9 KND94759.1 - 8.3e-61 205.3 5.9 8.3e-61 205.3 4.1 2.8 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KND94759.1 - 3.4e-45 153.6 3.2 5.7e-45 152.8 0.2 2.8 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KND94759.1 - 6.9e-23 80.3 3.2 6.9e-23 80.3 2.2 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain HEAT PF02985.17 KND94759.1 - 4.7e-16 57.3 3.2 0.0052 16.7 0.0 8.0 7 0 0 7 7 7 4 HEAT repeat Helicase_C PF00271.26 KND94759.1 - 9.5e-14 51.0 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KND94759.1 - 1.5e-07 31.7 0.4 0.42 11.0 0.0 4.1 3 0 0 3 3 3 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KND94759.1 - 0.011 15.1 0.3 1 8.6 0.1 3.3 4 0 0 4 4 4 0 CLASP N terminal zf-rbx1 PF12678.2 KND94760.1 - 7.4e-10 38.7 8.0 1e-07 31.9 0.5 2.6 2 0 0 2 2 2 2 RING-H2 zinc finger zf-RING_2 PF13639.1 KND94760.1 - 2e-09 37.1 19.8 9.1e-09 35.0 0.5 3.9 3 1 1 4 4 4 1 Ring finger domain PHD PF00628.24 KND94760.1 - 3.6e-09 36.1 6.7 3.6e-09 36.1 4.6 2.6 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KND94760.1 - 4.2e-07 29.1 2.9 4.2e-07 29.1 2.0 2.3 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.20 KND94760.1 - 6.5e-06 25.7 0.1 6.5e-06 25.7 0.1 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND94760.1 - 4.3e-05 23.0 0.2 4.3e-05 23.0 0.2 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND94760.1 - 0.00015 21.5 8.8 0.0034 17.1 0.2 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KND94760.1 - 0.00048 19.8 5.4 0.0012 18.5 1.4 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 KND94760.1 - 0.00056 19.5 4.4 0.00056 19.5 3.0 3.6 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND94760.1 - 0.001 19.0 0.8 0.001 19.0 0.6 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KND94760.1 - 0.0019 17.6 6.2 0.002 17.5 0.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 KND94760.1 - 0.03 13.6 3.0 0.056 12.7 0.5 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_6 PF14835.1 KND94760.1 - 0.048 13.4 0.4 0.048 13.4 0.3 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PrkA PF06798.7 KND94760.1 - 0.06 12.6 0.7 0.12 11.6 0.5 1.5 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain RecR PF02132.10 KND94760.1 - 3.5 7.1 11.2 4 6.9 0.8 3.3 3 0 0 3 3 3 0 RecR protein PHF5 PF03660.9 KND94760.1 - 7.7 6.6 10.6 0.078 13.0 1.2 2.1 3 0 0 3 3 2 0 PHF5-like protein MRP-L46 PF11788.3 KND94761.1 - 8e-24 84.4 0.1 1.3e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KND94761.1 - 0.00025 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Herpes_LMP2 PF07415.6 KND94761.1 - 0.033 12.7 0.2 4.1 5.8 0.0 2.0 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein VTC PF09359.5 KND94762.1 - 9.9e-102 339.7 0.9 1.1e-101 339.6 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KND94762.1 - 1.7e-23 83.7 6.6 3e-11 43.6 0.0 3.5 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 KND94762.1 - 2.9e-12 46.6 2.4 6.7e-12 45.4 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TrmB PF01978.14 KND94762.1 - 0.0028 17.3 0.1 0.011 15.4 0.1 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.14 KND94762.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Glyco_transf_29 PF00777.13 KND94762.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) 7TMR-DISM_7TM PF07695.6 KND94762.1 - 0.31 10.6 4.2 0.47 10.0 2.9 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling MCM PF00493.18 KND94763.1 - 9e-138 458.5 0.1 1.2e-137 458.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KND94763.1 - 2.8e-20 73.0 0.1 9.7e-19 68.0 0.0 2.9 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND94763.1 - 4.6e-05 22.6 0.0 0.00063 18.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND94763.1 - 9.9e-05 22.0 0.2 0.0013 18.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KND94763.1 - 0.0031 17.1 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KND94763.1 - 0.0078 14.9 0.4 0.013 14.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain Rad21_Rec8_N PF04825.8 KND94764.1 - 4e-39 132.9 0.0 7.3e-39 132.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KND94764.1 - 9.8e-09 34.2 0.1 2.2e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KND94764.1 - 0.062 12.8 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 ScpA/B protein THOC7 PF05615.8 KND94765.1 - 4.8e-36 124.0 0.7 4.8e-36 124.0 0.5 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 TMEM247 PF15444.1 KND94765.1 - 0.077 12.8 0.0 0.077 12.8 0.0 3.1 1 1 2 3 3 3 0 Transmembrane protein 247 FUSC PF04632.7 KND94765.1 - 0.089 11.2 6.9 0.12 10.7 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 KND94765.1 - 0.17 10.8 6.7 0.24 10.3 4.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 KND94765.1 - 0.45 10.5 5.8 0.81 9.6 4.0 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein RTBV_P46 PF06216.6 KND94765.1 - 2.1 7.0 5.1 1.1 8.0 1.4 1.7 1 1 0 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF972 PF06156.8 KND94765.1 - 4 7.8 8.3 20 5.5 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 KND94765.1 - 8.4 6.0 10.4 20 4.8 6.1 1.9 1 1 1 2 2 2 0 Mnd1 family zf-CCCH PF00642.19 KND94768.1 - 1.1e-10 40.9 20.1 4.2e-06 26.2 0.7 4.4 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KND94768.1 - 0.43 10.1 3.2 14 5.2 0.0 3.0 3 0 0 3 3 3 0 Putative zinc-finger domain LRV_FeS PF05484.6 KND94768.1 - 0.66 9.5 9.2 0.16 11.5 0.5 3.2 2 1 1 3 3 3 0 LRV protein FeS4 cluster Sua5_yciO_yrdC PF01300.13 KND94769.1 - 9.9e-54 181.2 0.0 1.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KND94769.1 - 5.3e-26 91.1 0.0 1.1e-25 90.1 0.0 1.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.15 KND94770.1 - 2.2e-15 56.6 1.0 3e-14 52.9 0.7 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain COG4 PF08318.7 KND94771.1 - 2.1e-91 306.1 0.0 2.8e-91 305.7 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein DUF2379 PF09543.5 KND94771.1 - 0.018 15.0 0.1 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Nsp1_C PF05064.8 KND94771.1 - 0.025 14.2 0.2 3.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region HSCB_C PF07743.8 KND94771.1 - 0.045 14.2 3.5 0.46 10.9 0.1 3.2 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain E1-E2_ATPase PF00122.15 KND94772.1 - 1.6e-72 243.3 0.1 3.4e-72 242.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND94772.1 - 3.6e-46 156.9 0.9 6.7e-46 156.0 0.6 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND94772.1 - 6.6e-30 105.1 0.0 9.9e-29 101.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KND94772.1 - 6.2e-19 67.2 0.0 1.5e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KND94772.1 - 4.3e-14 53.1 0.0 1.1e-13 51.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND94772.1 - 1.4e-13 50.6 0.0 2.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND94772.1 - 9.5e-05 22.0 1.5 0.00011 21.9 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Transport_MerF PF11431.3 KND94772.1 - 5.2 6.7 6.6 0.51 10.0 0.1 2.5 3 0 0 3 3 3 0 Membrane transport protein MerF VPS9 PF02204.13 KND94773.1 - 1.8e-23 82.5 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain AA_kinase PF00696.23 KND94775.1 - 4.9e-37 127.7 0.7 7.1e-37 127.2 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KND94775.1 - 1e-16 60.4 1.5 4.3e-16 58.3 0.1 2.3 2 0 0 2 2 2 1 PUA domain tRNA-synt_2b PF00587.20 KND94776.1 - 5e-68 228.0 0.0 1.1e-67 226.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND94776.1 - 3.1e-22 78.3 3.1 2.4e-21 75.4 0.0 3.4 4 0 0 4 4 4 1 Anticodon binding domain SNF5 PF04855.7 KND94777.1 - 4e-75 252.4 0.2 7.7e-75 251.5 0.2 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.6 KND94777.1 - 0.00055 19.9 3.1 0.00055 19.9 2.1 3.5 3 1 1 4 4 4 1 INO80 complex subunit Ies4 HEAT_2 PF13646.1 KND94778.1 - 1.5e-05 25.1 0.7 0.0073 16.5 0.0 4.8 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.17 KND94778.1 - 0.0027 17.6 0.3 0.28 11.3 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KND94778.1 - 0.011 16.2 0.0 0.011 16.2 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat DUF1098 PF06497.6 KND94778.1 - 0.049 13.6 0.3 0.8 9.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) DUF131 PF01998.12 KND94779.1 - 0.17 11.2 5.5 0.28 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF131 mRNA_cap_enzyme PF01331.14 KND94780.1 - 3.8e-51 173.5 0.2 4.9e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KND94780.1 - 1.6e-22 79.8 0.4 3.3e-22 78.8 0.3 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KND94780.1 - 4.5e-08 32.7 0.1 1.2e-06 28.0 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Vip3A_N PF12495.3 KND94780.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Pkinase PF00069.20 KND94781.1 - 5e-71 238.9 0.1 9.8e-71 237.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94781.1 - 2.7e-53 180.6 0.1 5.5e-53 179.6 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KND94781.1 - 9e-23 80.4 0.8 2e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 KND94781.1 - 9.6e-08 32.2 0.9 3e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 KND94781.1 - 6.3e-07 28.6 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND94781.1 - 0.0022 17.7 4.9 0.0064 16.2 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KND94781.1 - 0.03 13.3 0.2 0.065 12.2 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDRGK PF09756.4 KND94781.1 - 4.2 6.7 12.6 11 5.4 8.7 1.6 1 0 0 1 1 1 0 DDRGK domain PUF PF00806.14 KND94782.1 - 2.4e-26 89.6 0.0 0.0001 21.5 0.0 6.2 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KND94782.1 - 2.6e-13 49.4 0.0 5.1e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94782.1 - 2.2e-07 30.7 0.1 5.8e-06 26.1 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND94782.1 - 3.5e-06 26.7 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 KND94783.1 - 2.8e-15 55.7 20.2 1e-09 37.9 7.1 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 KND94783.1 - 0.0054 16.4 10.6 0.21 11.3 1.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KND94783.1 - 0.097 12.4 16.6 1.1 9.1 1.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 KND94783.1 - 0.67 9.2 8.1 1.7 7.8 1.5 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KND94783.1 - 1.6 8.1 15.6 0.37 10.1 3.8 3.0 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.19 KND94784.1 - 6.7e-09 35.6 0.1 9.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Zn_clus PF00172.13 KND94785.1 - 1.8e-08 34.1 6.2 3.6e-08 33.1 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND94785.1 - 1.8e-06 26.8 0.2 2.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chromo PF00385.19 KND94786.1 - 2.1e-10 40.1 2.9 3.9e-06 26.4 0.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain CDC27 PF09507.5 KND94786.1 - 0.045 12.9 17.7 0.065 12.4 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-RING_UBOX PF13445.1 KND94787.1 - 0.002 17.7 0.2 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KND94787.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Ring finger domain Rer1 PF03248.8 KND94788.1 - 3.4e-79 264.5 7.0 3.9e-79 264.3 4.8 1.0 1 0 0 1 1 1 1 Rer1 family FUSC_2 PF13515.1 KND94788.1 - 0.01 15.7 0.5 0.01 15.7 0.3 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like 2TM PF13239.1 KND94788.1 - 0.84 9.7 9.8 6.1 6.9 0.2 2.2 2 0 0 2 2 2 0 2TM domain Paf1 PF03985.8 KND94789.1 - 9.7e-56 189.3 1.6 3.3e-55 187.6 1.1 1.7 1 1 0 1 1 1 1 Paf1 Nucleoside_tran PF01733.13 KND94790.1 - 2.2e-39 135.4 11.9 5.5e-36 124.2 8.3 2.2 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 KND94790.1 - 0.39 9.3 42.2 0.026 13.2 4.3 3.0 1 1 1 2 2 2 0 Major Facilitator Superfamily HET PF06985.6 KND94792.1 - 1.3e-18 67.4 0.0 5.7e-18 65.4 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.14 KND94793.1 - 2e-159 530.3 1.3 2.7e-159 529.9 0.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KND94793.1 - 2.7e-19 68.7 0.0 4.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive SYF2 PF08231.7 KND94794.1 - 7.4e-51 172.2 13.2 7.4e-51 172.2 9.2 2.4 2 1 0 2 2 2 1 SYF2 splicing factor TMP_2 PF06791.8 KND94794.1 - 1.5 8.4 12.2 2.5 7.6 8.5 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein YEATS PF03366.11 KND94795.1 - 3.4e-29 100.3 0.2 5.3e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 YEATS family DUF2404 PF10296.4 KND94796.1 - 0.00011 22.2 0.0 0.00062 19.8 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 KND94797.1 - 5.5e-34 117.6 0.0 3.7e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Inositol-pentakisphosphate 2-kinase Phosphoesterase PF04185.9 KND94798.1 - 5.8e-31 108.0 1.8 1e-30 107.2 0.8 1.7 1 1 1 2 2 2 1 Phosphoesterase family Far-17a_AIG1 PF04750.9 KND94799.1 - 4.7e-53 179.3 14.1 5.4e-53 179.1 9.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Ferritin_2 PF13668.1 KND94800.1 - 1.3e-46 157.9 3.5 2e-46 157.3 2.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.1 KND94800.1 - 0.003 18.0 0.2 0.0055 17.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) WD40 PF00400.27 KND94801.1 - 1.5e-12 46.8 0.1 0.0063 16.3 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Indigoidine_A PF04227.7 KND94802.1 - 1.5e-101 339.5 1.8 2e-101 339.0 1.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KND94802.1 - 2.3e-20 72.9 0.5 2.2e-19 69.7 0.0 2.7 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Ins_P5_2-kin PF06090.7 KND94802.1 - 0.047 12.7 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase HTH_DeoR PF08220.7 KND94802.1 - 0.21 11.1 1.0 1.4 8.4 0.3 2.6 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain FMN_dh PF01070.13 KND94803.1 - 3.6e-127 424.0 0.0 4.1e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KND94803.1 - 8.6e-07 28.4 3.5 1.3e-06 27.7 2.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KND94803.1 - 0.00011 21.2 0.9 0.00057 18.8 0.2 2.0 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KND94803.1 - 0.00021 20.3 0.3 0.00031 19.7 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KND94803.1 - 0.0029 16.7 2.1 0.069 12.2 0.7 2.2 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KND94803.1 - 0.012 14.8 0.6 0.051 12.8 0.3 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.16 KND94803.1 - 0.14 11.1 0.2 0.57 9.1 0.0 1.8 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase Sld5 PF05916.6 KND94804.1 - 1.8e-10 41.0 0.2 2.9e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Calreticulin PF00262.13 KND94805.1 - 4.1e-161 535.7 17.3 6.4e-161 535.0 12.0 1.3 1 0 0 1 1 1 1 Calreticulin family adh_short PF00106.20 KND94806.1 - 1.1e-25 90.4 0.1 1.8e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND94806.1 - 3.8e-12 46.4 0.0 5.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND94806.1 - 3.2e-09 36.7 0.1 6.8e-09 35.6 0.1 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KND94806.1 - 0.0055 15.4 0.0 0.0075 15.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KND94806.1 - 0.025 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.14 KND94807.1 - 4.7e-75 252.8 0.0 5.8e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KND94807.1 - 3.3e-34 117.9 0.0 5.6e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KND94807.1 - 1.8e-05 24.7 0.0 0.00014 21.8 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND94807.1 - 0.0001 22.2 0.1 0.00026 20.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KND94807.1 - 0.00028 19.4 0.1 0.00048 18.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KND94807.1 - 0.0021 18.1 0.2 0.0065 16.5 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND94807.1 - 0.0071 15.0 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.19 KND94807.1 - 0.0098 14.8 0.1 0.03 13.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND94807.1 - 0.01 14.7 0.2 0.016 14.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KND94807.1 - 0.013 15.8 0.0 0.06 13.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND94807.1 - 0.016 14.1 0.1 0.025 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.1 KND94807.1 - 0.024 14.9 0.1 0.067 13.5 0.0 1.8 2 0 0 2 2 1 0 XdhC Rossmann domain Thi4 PF01946.12 KND94807.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KND94807.1 - 0.065 12.8 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KND94807.1 - 0.067 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 KND94807.1 - 0.16 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Fringe PF02434.11 KND94808.1 - 4.2e-06 26.1 0.0 6.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 KND94808.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 PAN domain DEAD PF00270.24 KND94809.1 - 2.7e-40 137.6 0.0 1.6e-39 135.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND94809.1 - 6.3e-25 86.8 1.1 1.3e-24 85.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KND94809.1 - 0.0012 19.1 3.0 0.0012 19.1 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) ResIII PF04851.10 KND94809.1 - 0.044 13.6 0.0 0.19 11.5 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PRAI PF00697.17 KND94809.1 - 0.095 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3334 PF11813.3 KND94809.1 - 0.099 12.1 0.0 0.099 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Pkinase PF00069.20 KND94810.1 - 0.00062 19.0 0.0 0.0007 18.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94810.1 - 0.05 12.6 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PHD PF00628.24 KND94811.1 - 1.1e-09 37.8 7.1 2e-09 37.0 4.9 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KND94811.1 - 0.017 15.3 0.0 0.055 13.7 0.0 1.9 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 KND94811.1 - 0.19 11.8 1.4 0.4 10.8 1.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Glyco_hydro_2_N PF02837.13 KND94814.1 - 7.9e-08 32.0 0.3 1.4e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KND94814.1 - 5e-05 23.7 0.0 9.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KND94814.1 - 8.5e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ribosomal_L10 PF00466.15 KND94818.1 - 2.3e-24 85.2 0.1 4.9e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KND94818.1 - 7.4e-17 61.5 5.6 3.8e-16 59.2 3.0 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pkinase PF00069.20 KND94819.1 - 1.6e-76 256.9 0.0 4.3e-76 255.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94819.1 - 3.5e-37 127.8 0.0 7.1e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KND94819.1 - 5.4e-15 55.2 0.1 1e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 FHA domain PCI PF01399.22 KND94819.1 - 2.1e-13 50.4 0.2 7e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain Kinase-like PF14531.1 KND94819.1 - 5.9e-09 35.2 0.0 5.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND94819.1 - 0.018 14.1 0.2 0.12 11.4 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KND94819.1 - 0.019 13.8 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ADK PF00406.17 KND94820.1 - 2.8e-45 153.8 0.0 4.4e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KND94820.1 - 6.1e-09 35.8 0.8 1e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND94820.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND94820.1 - 5e-06 27.3 0.0 8.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KND94820.1 - 0.024 14.0 3.6 1.9 7.8 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase DUF3446 PF11928.3 KND94820.1 - 0.26 11.4 1.3 0.56 10.4 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF2802 PF10975.3 KND94820.1 - 7.2 6.4 10.8 15 5.4 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Nucleoplasmin PF03066.10 KND94822.1 - 0.027 13.9 0.3 0.041 13.3 0.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KND94823.1 - 0.00031 19.4 5.2 0.00031 19.4 3.6 2.3 2 0 0 2 2 2 1 Daxx Family Cgr1 PF03879.9 KND94825.1 - 2.5e-37 127.3 29.6 3e-37 127.0 20.5 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 KND94825.1 - 0.34 11.2 10.6 0.42 10.9 7.3 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PAPS_reduct PF01507.14 KND94825.1 - 0.41 10.4 3.9 0.48 10.2 2.7 1.1 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ax_dynein_light PF10211.4 KND94825.1 - 2.9 7.6 20.3 3.9 7.2 14.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain RR_TM4-6 PF06459.7 KND94825.1 - 3.1 7.6 12.2 3.5 7.4 8.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Silic_transp PF03842.8 KND94825.1 - 7.8 4.4 5.6 8.9 4.2 3.9 1.0 1 0 0 1 1 1 0 Silicon transporter OmpH PF03938.9 KND94825.1 - 8 6.3 13.8 9.2 6.1 9.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 KND94825.1 - 9 5.2 12.0 9.8 5.1 8.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KND94826.1 - 0.016 14.4 0.5 0.022 13.9 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KND94826.1 - 0.028 14.5 0.7 0.064 13.3 0.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KND94826.1 - 0.051 13.4 1.1 0.21 11.4 0.1 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Innate_immun PF12782.2 KND94826.1 - 0.077 12.2 4.3 0.11 11.6 3.0 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family PqqD PF05402.7 KND94826.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Atg14 PF10186.4 KND94826.1 - 0.32 9.9 6.9 0.47 9.3 0.2 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KND94826.1 - 0.32 10.5 2.5 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator SelP_N PF04592.9 KND94826.1 - 3.2 7.0 9.9 5.1 6.4 6.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PTS_2-RNA PF01885.11 KND94827.1 - 1.3e-63 213.7 0.0 1.5e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2361 PF10153.4 KND94829.1 - 1.6e-27 95.9 4.7 1.6e-27 95.9 3.3 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DMAP_binding PF06464.6 KND94829.1 - 0.002 18.6 0.2 0.002 18.6 0.2 2.2 2 0 0 2 2 2 1 DMAP1-binding Domain Viral_env_E26 PF11050.3 KND94829.1 - 0.18 11.0 4.1 0.11 11.6 1.3 1.7 1 1 1 2 2 2 0 Virus envelope protein E26 dsrm PF00035.20 KND94830.1 - 3.4e-05 24.3 0.0 0.00032 21.2 0.0 2.5 2 1 0 2 2 2 1 Double-stranded RNA binding motif Pkinase PF00069.20 KND94831.1 - 4.5e-58 196.4 0.0 6.4e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94831.1 - 3.9e-21 75.2 0.0 6.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94831.1 - 1.7e-05 23.9 0.0 2.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND94831.1 - 0.0036 17.0 0.8 0.016 14.9 0.1 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND94831.1 - 0.006 15.9 0.1 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 KND94831.1 - 0.13 12.6 0.0 0.96 9.8 0.0 2.4 2 0 0 2 2 2 0 PAS domain Seadorna_VP7 PF07387.6 KND94831.1 - 0.34 9.7 0.0 0.57 8.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_2 PF13639.1 KND94832.1 - 0.57 10.0 11.4 0.7 9.7 5.4 2.9 2 1 0 2 2 2 0 Ring finger domain His_Phos_1 PF00300.17 KND94833.1 - 3.7e-24 85.6 0.0 5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.2 KND94834.1 - 3.7e-12 45.7 0.1 1.2e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KND94834.1 - 6.7e-12 44.1 0.4 0.023 14.7 0.0 7.8 9 0 0 9 9 9 3 Leucine Rich repeat F-box PF00646.28 KND94834.1 - 7.2e-08 31.8 0.0 2.3e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 KND94834.1 - 1.2e-07 30.7 6.5 0.22 11.6 0.1 7.7 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.2 KND94834.1 - 2.1e-06 27.1 2.8 1 9.0 0.0 5.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND94834.1 - 2.6e-05 23.8 2.0 0.0093 15.7 0.0 4.3 4 1 1 5 5 5 1 Leucine rich repeat PRANC PF09372.5 KND94834.1 - 0.05 13.5 0.6 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 PRANC domain LRR_7 PF13504.1 KND94834.1 - 0.2 11.9 10.3 12 6.6 0.2 6.5 7 0 0 7 7 7 0 Leucine rich repeat UAA PF08449.6 KND94835.1 - 1.4e-71 240.9 4.6 3.8e-71 239.5 3.2 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KND94835.1 - 5.6e-11 42.5 20.5 3.7e-07 30.2 3.1 3.4 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 KND94835.1 - 7e-07 28.6 3.4 0.011 14.8 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KND94835.1 - 3e-05 24.1 18.5 4.2e-05 23.7 3.3 3.1 2 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KND94835.1 - 0.00043 19.9 3.9 0.00043 19.9 2.7 2.7 3 0 0 3 3 3 1 Triose-phosphate Transporter family Vint PF14623.1 KND94835.1 - 0.074 12.5 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Hint-domain UPF0546 PF10639.4 KND94835.1 - 3.4 7.5 7.3 0.78 9.5 1.7 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 DSPc PF00782.15 KND94836.1 - 2e-24 85.6 0.0 2.4e-21 75.7 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KND94836.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4574 PF15141.1 KND94838.1 - 2.3 7.9 8.6 1.5 8.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4574) Serinc PF03348.10 KND94838.1 - 5.1 5.6 6.5 8.4 4.9 0.1 2.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) IU_nuc_hydro PF01156.14 KND94839.1 - 1.8e-44 152.2 0.3 3.1e-31 108.7 0.1 2.2 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Cyclin_N PF00134.18 KND94841.1 - 1.7e-10 40.5 0.1 3.4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 KND94842.1 - 2.5e-51 169.8 19.3 7.8e-11 41.4 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 KND94842.1 - 1.3e-14 53.1 2.4 2.3e-14 52.3 1.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 KND94842.1 - 0.0013 17.9 0.1 0.057 12.5 0.0 2.4 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 KND94842.1 - 0.0099 15.6 0.0 4.9 6.8 0.0 4.0 3 1 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Rad60-SLD PF11976.3 KND94844.1 - 1.2e-18 66.5 0.1 2.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KND94844.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Zn_clus PF00172.13 KND94846.1 - 1.2e-06 28.3 10.5 2.3e-06 27.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 KND94846.1 - 7.3e-06 25.2 0.1 7.3e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Aflatoxin regulatory protein PCI PF01399.22 KND94847.1 - 6.6e-10 39.2 2.4 1.4e-09 38.2 0.0 2.8 3 0 0 3 3 3 1 PCI domain CAF-1_p150 PF11600.3 KND94847.1 - 0.00011 21.6 17.5 0.00011 21.6 12.1 3.4 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal GFA PF04828.9 KND94848.1 - 0.0002 21.2 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme APH PF01636.18 KND94849.1 - 2.2e-43 148.7 0.0 4.7e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KND94849.1 - 3.4e-09 36.2 0.2 1.2e-07 31.1 0.0 2.8 2 1 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KND94849.1 - 0.0016 17.4 0.0 0.0044 16.0 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.15 KND94849.1 - 0.0044 16.6 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KND94849.1 - 0.0097 15.2 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 1 RIO1 family DUF4137 PF13593.1 KND94850.1 - 7.9e-77 258.4 18.7 1.3e-76 257.7 12.9 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) CBFB_NFYA PF02045.10 KND94851.1 - 1.7e-30 105.3 4.8 4e-30 104.1 3.3 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KND94851.1 - 0.062 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein PAT1 PF09770.4 KND94851.1 - 7.2 4.7 36.4 10 4.1 25.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Erf4 PF10256.4 KND94852.1 - 1.7e-28 98.8 0.0 2.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4203 PF13886.1 KND94856.1 - 6e-32 110.8 25.8 7.9e-32 110.4 17.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4342 PF14242.1 KND94856.1 - 0.15 11.8 0.2 0.46 10.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Rrn6 PF10214.4 KND94857.1 - 0.93 7.5 5.4 1.1 7.3 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF605 PF04652.11 KND94857.1 - 1.1 8.5 18.6 1.2 8.4 12.9 1.2 1 0 0 1 1 1 0 Vta1 like STE3 PF02076.10 KND94858.1 - 1e-41 142.9 14.5 1.3e-41 142.5 10.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor VRR_NUC PF08774.6 KND94859.1 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Gar1 PF04410.9 KND94860.1 - 4.8e-40 136.5 0.1 4.8e-40 136.5 0.0 2.1 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Dpy-30 PF05186.8 KND94861.1 - 2.3e-15 55.7 0.0 3.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif SSB PF00436.20 KND94862.1 - 1e-18 67.0 0.0 1.3e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Ribosomal_S13_N PF08069.7 KND94863.1 - 4.7e-28 96.8 0.1 1e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KND94863.1 - 1.4e-21 76.0 0.0 2.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KND94863.1 - 0.022 14.4 0.1 0.056 13.1 0.0 1.8 2 0 0 2 2 2 0 'Paired box' domain OGG_N PF07934.7 KND94864.1 - 2.1e-34 117.9 0.0 3.9e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KND94864.1 - 1.4e-15 57.4 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KND94864.1 - 0.0071 15.9 0.0 0.023 14.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Adeno_VII PF03228.9 KND94864.1 - 0.038 14.5 1.8 0.11 13.0 1.2 1.9 1 1 0 1 1 1 0 Adenoviral core protein VII ABC_membrane PF00664.18 KND94865.1 - 3.4e-87 292.3 38.6 6.7e-44 150.3 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND94865.1 - 1.6e-67 226.0 0.0 1.3e-32 112.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND94865.1 - 4.2e-13 49.0 0.0 5.9e-05 22.3 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND94865.1 - 1.3e-09 38.4 2.0 0.26 11.2 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND94865.1 - 3.5e-09 36.0 0.6 0.00022 20.6 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KND94865.1 - 9.5e-08 32.2 3.5 0.0014 18.6 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KND94865.1 - 3.2e-07 31.2 0.0 0.032 15.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KND94865.1 - 6.3e-07 28.3 4.5 0.0059 15.2 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KND94865.1 - 6.5e-07 28.6 0.1 0.068 12.3 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KND94865.1 - 6.2e-05 22.4 0.4 0.49 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KND94865.1 - 0.00073 19.4 2.1 1.2 9.0 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KND94865.1 - 0.0016 18.7 0.0 3.2 8.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KND94865.1 - 0.0025 17.6 0.0 3.3 7.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KND94865.1 - 0.0042 16.9 0.0 3.2 7.6 0.0 3.8 4 1 1 5 5 4 1 AAA domain AAA_22 PF13401.1 KND94865.1 - 0.0055 16.8 4.1 2.2 8.4 0.2 3.8 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND94865.1 - 0.0094 15.6 0.2 9.2 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KND94865.1 - 0.01 14.5 0.0 1.2 7.7 0.0 2.3 2 1 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.12 KND94865.1 - 0.016 14.9 3.0 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KND94865.1 - 0.021 15.1 1.9 4.8 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KND94865.1 - 0.033 14.1 4.5 0.68 9.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 KND94865.1 - 0.034 13.6 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KND94865.1 - 0.046 13.1 2.5 11 5.2 0.2 3.6 4 0 0 4 4 4 0 AAA-like domain TMPIT PF07851.8 KND94865.1 - 0.057 12.4 0.8 0.85 8.6 0.1 2.6 2 0 0 2 2 2 0 TMPIT-like protein MobB PF03205.9 KND94865.1 - 0.082 12.6 0.2 15 5.2 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KND94865.1 - 0.13 12.2 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 KND94865.1 - 0.14 12.3 0.2 17 5.6 0.0 3.3 3 0 0 3 3 2 0 RNA helicase Tubulin-binding PF00418.14 KND94865.1 - 0.15 11.7 0.4 0.33 10.6 0.3 1.6 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat DUF1183 PF06682.7 KND94866.1 - 5.3e-85 285.8 11.0 1.1e-84 284.7 7.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) MFS_1 PF07690.11 KND94868.1 - 3.3e-39 134.6 44.7 3.3e-39 134.6 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94868.1 - 0.0023 16.5 18.6 0.0023 16.5 12.9 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1996 PF09362.5 KND94869.1 - 2.8e-63 213.7 0.1 4e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KND94869.1 - 1e-18 67.0 7.7 1e-18 67.0 5.3 2.2 2 0 0 2 2 2 1 WSC domain Metallophos PF00149.23 KND94870.1 - 0.003 16.9 0.0 0.003 16.9 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Velvet PF11754.3 KND94871.1 - 5.3e-53 179.6 0.0 9e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 Velvet factor RRM_1 PF00076.17 KND94874.1 - 9.3e-26 89.2 0.1 9.5e-13 47.5 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND94874.1 - 8e-21 73.8 0.0 2.9e-10 39.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND94874.1 - 2.5e-15 56.0 0.0 1.4e-06 28.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KND94875.1 - 6.4e-11 41.6 4.0 2.5e-10 39.7 2.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3336 PF11815.3 KND94876.1 - 1.1e-33 115.7 0.3 3.4e-33 114.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KND94876.1 - 3.9e-15 56.3 0.2 1.1e-14 54.9 0.1 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3818 PF12825.2 KND94877.1 - 8.6e-136 452.0 4.5 1.2e-135 451.5 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KND94877.1 - 1.3e-36 125.2 2.9 3.3e-28 98.0 0.1 2.8 3 0 0 3 3 3 2 PX-associated PX PF00787.19 KND94877.1 - 5.6e-15 55.1 0.0 7.3e-14 51.5 0.0 2.8 3 1 0 3 3 3 1 PX domain Myc_N PF01056.13 KND94877.1 - 0.0022 17.2 0.6 0.005 16.0 0.4 1.5 1 0 0 1 1 1 1 Myc amino-terminal region Usp PF00582.21 KND94877.1 - 1 9.5 3.4 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Universal stress protein family FAD_binding_2 PF00890.19 KND94878.1 - 4.1e-121 404.7 5.0 5.1e-121 404.4 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KND94878.1 - 3.4e-44 149.8 1.1 5.1e-44 149.2 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KND94878.1 - 2.1e-06 27.7 0.0 0.034 14.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND94878.1 - 5.8e-06 25.5 0.3 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KND94878.1 - 0.0012 17.7 3.1 0.052 12.3 1.1 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 KND94878.1 - 0.0027 16.6 0.7 0.0058 15.5 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KND94878.1 - 0.0087 15.1 0.5 0.022 13.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KND94878.1 - 0.18 10.2 1.0 0.54 8.6 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein UBA_4 PF14555.1 KND94879.1 - 6.5e-05 22.3 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 KND94879.1 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain PXA PF02194.10 KND94880.1 - 1.6e-34 119.0 0.0 3.7e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.1 KND94880.1 - 3e-26 91.0 6.4 5.9e-26 90.0 4.4 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Nexin_C PF08628.7 KND94880.1 - 0.0014 18.6 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal zf-MYND PF01753.13 KND94880.1 - 0.0076 16.1 0.9 0.019 14.8 0.6 1.6 1 0 0 1 1 1 1 MYND finger Herpes_BLLF1 PF05109.8 KND94880.1 - 2.6 5.9 7.4 3.8 5.3 5.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DEAD PF00270.24 KND94881.1 - 8.1e-12 44.9 0.0 4.8e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND94881.1 - 3.8e-06 26.6 0.0 8.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 KND94881.1 - 1.4e-05 25.1 0.0 0.00018 21.6 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Pkinase PF00069.20 KND94882.1 - 1.1e-34 119.8 0.0 7.1e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND94882.1 - 8.9e-14 51.1 0.0 9.6e-05 21.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KND94882.1 - 8.8e-07 28.8 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KND94882.1 - 0.041 12.8 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Glyco_hydro_38 PF01074.17 KND94883.1 - 9e-89 297.3 0.1 1.4e-88 296.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KND94883.1 - 2.5e-68 230.9 0.0 4.3e-68 230.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KND94883.1 - 5.8e-26 90.5 0.0 1.3e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_15 PF00723.16 KND94883.1 - 0.059 11.9 0.0 0.088 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 DUF1771 PF08590.5 KND94884.1 - 7.5e-14 51.5 10.1 2.2e-13 50.0 7.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KND94884.1 - 4.6e-10 39.5 0.2 1.7e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 KND94884.1 - 2.2e-07 30.4 3.3 0.00071 19.1 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KND94884.1 - 0.00033 20.7 0.3 0.011 15.8 0.0 2.5 2 0 0 2 2 2 1 HBS1 N-terminus CUE PF02845.11 KND94884.1 - 0.072 12.6 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 CUE domain TCP PF03634.8 KND94884.1 - 0.76 10.1 0.0 0.76 10.1 0.0 2.8 2 1 1 3 3 3 0 TCP family transcription factor SNARE_assoc PF09335.6 KND94885.1 - 1.3e-16 60.9 6.2 1.3e-16 60.9 4.3 3.0 2 1 2 4 4 4 1 SNARE associated Golgi protein FumaraseC_C PF10415.4 KND94885.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Fumarase C C-terminus DUF1049 PF06305.6 KND94885.1 - 0.068 12.6 0.0 0.068 12.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) FtsX PF02687.16 KND94885.1 - 4.3 7.1 11.5 5.8 6.6 2.7 3.0 1 1 1 2 2 2 0 FtsX-like permease family MutS_V PF00488.16 KND94887.1 - 1.1e-81 273.7 0.0 2.1e-81 272.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND94887.1 - 3.2e-37 128.3 7.4 5.4e-37 127.5 5.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KND94887.1 - 1.7e-20 73.1 0.0 7.3e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KND94887.1 - 7.8e-09 35.7 0.0 2.8e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KND94887.1 - 0.00039 20.5 0.0 0.00091 19.3 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KND94887.1 - 0.023 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cob_adeno_trans PF01923.13 KND94887.1 - 0.054 13.2 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_23 PF13476.1 KND94887.1 - 0.19 12.0 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.1 KND94889.1 - 1e-17 64.3 0.0 1.4e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND94889.1 - 1.9e-12 47.4 0.0 3.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND94889.1 - 2.3e-10 40.8 0.0 3.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND94889.1 - 3.2e-06 27.7 0.0 5.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND94889.1 - 4.9e-06 26.1 0.0 9.9e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KND94889.1 - 2.3e-05 23.2 0.0 3.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KND94889.1 - 0.0003 20.8 0.1 0.001 19.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND94889.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HSP20 PF00011.16 KND94890.1 - 2.7e-09 36.8 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family LRR_4 PF12799.2 KND94891.1 - 5.6e-10 38.6 11.4 0.00047 19.7 0.0 5.3 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KND94891.1 - 2.6e-07 30.0 10.6 0.57 10.4 0.0 7.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 KND94891.1 - 1.6e-05 24.2 4.9 12 6.4 0.1 6.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 KND94891.1 - 0.00091 18.9 8.1 0.53 10.0 0.0 5.1 4 2 0 4 4 4 2 Leucine rich repeat LETM1 PF07766.8 KND94891.1 - 0.0043 16.1 1.5 0.0047 16.0 0.0 1.7 2 0 0 2 2 2 1 LETM1-like protein LRR_7 PF13504.1 KND94891.1 - 0.0082 16.1 0.4 1.7e+02 3.1 0.0 5.6 5 0 0 5 5 5 0 Leucine rich repeat zf-C3HC4 PF00097.20 KND94893.1 - 9 6.0 17.1 7.1 6.3 1.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cytochrom_C1 PF02167.10 KND94894.1 - 3.9e-81 271.8 0.0 4.7e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KND94894.1 - 0.0031 17.6 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KND94894.1 - 0.06 14.1 0.2 0.21 12.4 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c Cpn60_TCP1 PF00118.19 KND94895.1 - 2.1e-124 415.7 19.0 2.5e-122 408.9 13.2 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KND94895.1 - 0.035 13.5 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 KND94896.1 - 2.4e-40 137.8 0.0 4.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND94896.1 - 4.2e-06 26.9 0.0 0.00061 19.9 0.0 2.8 3 1 0 3 3 1 1 AAA domain AAA_5 PF07728.9 KND94896.1 - 3.4e-05 23.6 0.1 0.00028 20.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND94896.1 - 0.00015 21.6 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KND94896.1 - 0.00039 20.4 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KND94896.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KND94896.1 - 0.0044 17.8 0.1 0.014 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND94896.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KND94896.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KND94896.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KND94896.1 - 0.022 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND94896.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND94896.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KND94896.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KND94896.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KND94896.1 - 0.084 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KND94896.1 - 0.11 12.0 0.0 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KND94896.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KND94896.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND94896.1 - 0.15 11.4 0.2 0.48 9.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain UCH PF00443.24 KND94899.1 - 5.6e-75 251.9 0.0 2.7e-74 249.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND94899.1 - 1.4e-19 70.6 0.0 5.1e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KND94899.1 - 5.9e-09 36.2 0.0 8.1e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 DUSP domain ubiquitin PF00240.18 KND94899.1 - 0.0019 17.5 0.0 0.0059 15.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Zn-ribbon_8 PF09723.5 KND94899.1 - 0.34 10.9 2.2 21 5.1 0.5 2.9 2 0 0 2 2 2 0 Zinc ribbon domain RNA_pol_L_2 PF13656.1 KND94900.1 - 3.1e-30 103.4 0.0 6.1e-30 102.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KND94900.1 - 3.8e-09 35.5 0.0 6.3e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BSP_II PF05432.6 KND94900.1 - 0.17 11.1 6.5 0.22 10.7 4.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Tankyrase_bdg_C PF15327.1 KND94900.1 - 0.29 11.3 3.9 0.42 10.7 2.7 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain MSA-2c PF12238.3 KND94900.1 - 2.4 7.7 5.7 2.6 7.6 3.0 1.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c Complex1_LYR_1 PF13232.1 KND94901.1 - 1.9e-07 31.1 0.1 3.1e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KND94901.1 - 1.3e-06 28.1 0.1 2.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KND94901.1 - 1.2e-05 25.6 0.0 1.5e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF605 PF04652.11 KND94902.1 - 4.4 6.6 10.2 5.6 6.2 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KND94903.1 - 3.5e-56 190.2 0.0 7.1e-56 189.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94903.1 - 1.7e-32 112.5 0.0 6.9e-31 107.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94903.1 - 1.7e-08 33.8 0.0 1e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND94903.1 - 0.00063 19.5 0.1 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAMP PF00672.20 KND94904.1 - 4.2e-47 158.2 20.0 1.4e-10 41.1 0.3 7.0 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KND94904.1 - 1.3e-30 105.3 0.2 5.3e-30 103.3 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KND94904.1 - 1.2e-28 99.3 0.2 1.6e-25 89.2 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 KND94904.1 - 6.6e-18 64.4 0.6 6.6e-18 64.4 0.4 4.2 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 KND94904.1 - 0.0085 14.6 15.2 0.088 11.2 0.0 3.8 1 1 3 5 5 5 3 AAA domain DUF2365 PF10157.4 KND94904.1 - 0.056 13.3 16.0 8.4 6.2 0.1 7.1 5 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) Pox_A_type_inc PF04508.7 KND94904.1 - 0.15 11.8 6.5 2.9 7.9 0.2 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF883 PF05957.8 KND94904.1 - 0.52 10.7 20.0 1.2 9.5 0.5 5.9 4 2 3 7 7 7 0 Bacterial protein of unknown function (DUF883) Syntaphilin PF15290.1 KND94904.1 - 0.68 9.3 9.6 6.9 6.0 0.0 3.3 3 0 0 3 3 3 0 Golgi-localised syntaxin-1-binding clamp NAAA-beta PF15508.1 KND94904.1 - 0.71 10.2 7.0 6.2 7.2 0.1 5.5 5 2 3 8 8 8 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HMG_box PF00505.14 KND94906.1 - 1e-16 60.9 1.1 1.7e-16 60.1 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND94906.1 - 5.6e-15 55.4 1.7 1.1e-14 54.5 1.2 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KND94906.1 - 1.4e-10 41.1 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KND94906.1 - 5.2e-08 32.6 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WW PF00397.21 KND94907.1 - 1.2e-08 34.5 0.1 3.4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 WW domain Josephin PF02099.12 KND94908.1 - 0.1 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Josephin FAM101 PF15068.1 KND94908.1 - 3.7 6.9 6.2 3 7.2 2.1 2.5 3 0 0 3 3 3 0 FAM101 family Fungal_trans PF04082.13 KND94909.1 - 2.2e-18 66.0 0.0 4.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND94909.1 - 1.3e-06 28.1 13.5 2.1e-06 27.5 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.24 KND94910.1 - 5.9e-43 146.9 0.0 9.2e-37 126.6 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND94910.1 - 7.1e-13 48.6 0.1 2.5e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.21 KND94911.1 - 7.1e-06 26.0 20.6 0.0016 18.6 0.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND94911.1 - 0.051 13.9 0.3 0.051 13.9 0.2 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger DUF202 PF02656.10 KND94912.1 - 0.00043 20.4 3.5 0.00043 20.4 2.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) RseC_MucC PF04246.7 KND94912.1 - 0.024 14.2 0.4 0.024 14.2 0.3 1.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AAA_5 PF07728.9 KND94913.1 - 4e-117 386.2 0.0 3.5e-22 78.6 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KND94913.1 - 2.9e-28 98.0 0.0 1.6e-09 37.4 0.0 5.7 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KND94913.1 - 5.6e-27 94.5 0.0 0.0003 20.9 0.0 7.0 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND94913.1 - 1.6e-19 70.6 28.1 0.00048 20.1 0.0 10.3 9 1 0 9 9 7 5 AAA ATPase domain AAA_22 PF13401.1 KND94913.1 - 1.9e-18 66.8 1.0 0.013 15.6 0.0 8.4 8 0 0 8 8 7 4 AAA domain AAA_17 PF13207.1 KND94913.1 - 2.3e-18 67.1 0.1 0.0071 17.1 0.0 8.3 7 0 0 7 7 6 4 AAA domain AAA_33 PF13671.1 KND94913.1 - 3.7e-17 62.5 0.0 0.0037 17.1 0.0 7.4 7 1 0 7 7 6 3 AAA domain Sigma54_activat PF00158.21 KND94913.1 - 8.5e-17 61.1 0.0 0.0044 16.5 0.1 5.7 5 0 0 5 5 5 5 Sigma-54 interaction domain AAA_14 PF13173.1 KND94913.1 - 2.4e-16 59.8 0.0 0.00064 19.6 0.0 6.3 5 0 0 5 5 5 4 AAA domain T2SE PF00437.15 KND94913.1 - 6.5e-15 54.7 0.0 0.011 14.5 0.0 5.6 5 0 0 5 5 5 3 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 KND94913.1 - 7.1e-15 55.2 1.9 0.00011 22.2 0.2 6.7 8 0 0 8 8 5 2 Sigma-54 interaction domain NACHT PF05729.7 KND94913.1 - 2.6e-12 46.7 1.1 0.054 13.1 0.1 6.0 6 0 0 6 6 5 4 NACHT domain AAA_18 PF13238.1 KND94913.1 - 7.3e-12 45.7 6.8 0.23 11.7 0.0 7.0 7 0 0 7 7 5 3 AAA domain AAA_19 PF13245.1 KND94913.1 - 1.4e-11 43.9 2.3 0.09 12.5 0.0 6.4 6 0 0 6 6 6 3 Part of AAA domain DUF258 PF03193.11 KND94913.1 - 3.7e-11 42.4 3.1 0.034 13.3 0.2 6.2 6 0 0 6 6 6 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KND94913.1 - 3.7e-11 42.4 1.0 0.32 10.0 0.0 6.2 6 0 0 6 6 6 2 Zeta toxin UPF0079 PF02367.12 KND94913.1 - 1.9e-10 40.4 2.0 0.042 13.4 0.2 4.8 5 0 0 5 5 4 3 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KND94913.1 - 4.7e-10 39.9 0.9 0.11 12.7 0.0 6.7 6 1 0 6 6 6 2 ABC transporter RNA_helicase PF00910.17 KND94913.1 - 5.8e-10 39.3 1.0 0.48 10.6 0.0 6.2 6 0 0 6 6 5 1 RNA helicase Arch_ATPase PF01637.13 KND94913.1 - 1.2e-09 38.1 0.0 0.32 10.6 0.0 6.5 6 0 0 6 6 6 1 Archaeal ATPase IstB_IS21 PF01695.12 KND94913.1 - 1.6e-09 37.4 0.2 0.39 10.1 0.0 5.9 6 0 0 6 6 6 2 IstB-like ATP binding protein RuvB_N PF05496.7 KND94913.1 - 5e-09 35.5 0.6 0.11 11.4 0.0 5.7 5 0 0 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 KND94913.1 - 7.2e-09 36.1 0.4 4.1 7.9 0.0 5.9 5 0 0 5 5 5 0 Miro-like protein AAA_25 PF13481.1 KND94913.1 - 1.6e-08 34.1 0.5 0.26 10.6 0.0 5.3 4 0 0 4 4 4 1 AAA domain NTPase_1 PF03266.10 KND94913.1 - 2e-07 30.8 3.5 0.94 9.1 0.0 6.2 7 0 0 7 7 6 1 NTPase Mg_chelatase PF01078.16 KND94913.1 - 5e-07 29.0 0.9 2.4 7.2 0.0 6.6 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KND94913.1 - 5.4e-07 29.7 3.7 2 8.3 0.0 6.2 6 0 0 6 6 6 1 AAA domain AAA_29 PF13555.1 KND94913.1 - 1e-06 28.1 0.0 5.8 6.5 0.0 5.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain MobB PF03205.9 KND94913.1 - 3.3e-06 26.8 0.9 0.82 9.3 0.0 5.0 5 0 0 5 5 5 2 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KND94913.1 - 1.6e-05 24.4 1.5 0.55 9.6 0.1 4.9 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain TIP49 PF06068.8 KND94913.1 - 6.4e-05 21.8 0.8 1 7.9 0.0 4.2 5 0 0 5 5 5 1 TIP49 C-terminus AAA_7 PF12775.2 KND94913.1 - 0.00013 21.1 0.6 4.6 6.2 0.0 4.2 4 0 0 4 4 4 0 P-loop containing dynein motor region D3 PduV-EutP PF10662.4 KND94913.1 - 0.00016 21.1 1.9 1.6 8.2 0.1 4.5 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KND94913.1 - 0.00033 20.5 0.3 41 4.1 0.0 5.4 5 0 0 5 5 5 0 50S ribosome-binding GTPase NB-ARC PF00931.17 KND94913.1 - 0.0014 17.5 5.9 0.56 9.0 0.0 4.4 5 0 0 5 5 5 1 NB-ARC domain Viral_helicase1 PF01443.13 KND94913.1 - 0.0017 17.9 0.1 4.6 6.6 0.0 4.5 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 KND94913.1 - 0.0047 16.4 1.9 2.1 7.7 0.0 3.7 4 0 0 4 4 3 1 FtsK/SpoIIIE family Rad17 PF03215.10 KND94913.1 - 0.0071 15.0 0.5 1.7 7.1 0.0 4.1 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein PhoH PF02562.11 KND94913.1 - 0.039 13.1 0.4 16 4.6 0.0 4.1 4 0 0 4 4 4 0 PhoH-like protein KaiC PF06745.8 KND94913.1 - 0.055 12.5 0.0 35 3.3 0.0 4.0 4 0 0 4 4 4 0 KaiC AAA_6 PF12774.2 KND94913.1 - 0.41 10.1 0.0 27 4.1 0.0 3.7 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 Hpr_kinase_C PF07475.7 KND94913.1 - 1.4 8.1 3.6 1.8 7.8 0.1 2.9 4 0 0 4 4 3 0 HPr Serine kinase C-terminal domain ATP_bind_1 PF03029.12 KND94913.1 - 2.1 7.8 6.7 28 4.1 0.0 4.3 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein Isochorismatase PF00857.15 KND94914.1 - 4.4e-16 59.3 0.1 9.6e-16 58.1 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 KND94916.1 - 5e-18 65.8 0.0 6.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KND94916.1 - 7.2e-18 65.2 0.0 8.5e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2938 PF11158.3 KND94916.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) BP28CT PF08146.7 KND94917.1 - 5.5e-42 143.0 1.0 5.3e-41 139.8 0.1 3.0 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KND94917.1 - 4.5e-19 68.5 0.3 4.5e-19 68.5 0.2 4.7 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KND94917.1 - 1.8e-07 30.6 13.2 0.0025 17.7 0.1 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 KND94917.1 - 1.3e-06 28.5 13.6 0.3 11.3 0.0 6.8 6 0 0 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 KND94917.1 - 0.023 15.1 14.9 0.086 13.3 0.2 7.3 5 1 2 7 7 7 0 HEAT-like repeat Cullin PF00888.17 KND94917.1 - 0.034 12.6 0.0 0.062 11.8 0.0 1.3 1 0 0 1 1 1 0 Cullin family TMP-TENI PF02581.12 KND94918.1 - 4e-42 143.3 0.3 6.4e-42 142.6 0.2 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI HK PF02110.10 KND94918.1 - 1.3e-37 129.2 6.6 1.9e-37 128.8 4.6 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 KND94918.1 - 0.00014 21.2 0.7 0.00014 21.2 0.5 2.0 2 1 0 3 3 3 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KND94918.1 - 0.01 15.0 1.4 0.015 14.5 1.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Zn_clus PF00172.13 KND94919.1 - 4.2 7.3 13.1 7.7 6.5 9.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 KND94920.1 - 4.6e-78 262.7 0.0 5.8e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND94920.1 - 0.00025 19.4 0.0 0.00041 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KND94920.1 - 0.00031 19.6 0.0 0.00059 18.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF3405 PF11885.3 KND94920.1 - 0.01 14.1 0.1 0.015 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DegT_DnrJ_EryC1 PF01041.12 KND94920.1 - 0.032 13.2 0.3 0.066 12.2 0.2 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CTK3 PF12243.3 KND94921.1 - 1.3e-49 167.3 0.5 2.6e-49 166.4 0.3 1.6 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KND94921.1 - 1.4e-19 69.8 9.6 3.6e-19 68.5 6.7 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Ribosomal_L12 PF00542.14 KND94922.1 - 1.7e-19 69.5 7.6 1.6e-18 66.4 3.4 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 KND94922.1 - 0.19 11.8 1.3 3.2 7.9 0.0 2.5 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain BCNT PF07572.7 KND94923.1 - 5.2e-24 83.9 1.3 1.3e-23 82.7 0.9 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF4602 PF15375.1 KND94924.1 - 0.0003 20.8 1.6 0.0003 20.8 1.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) Daxx PF03344.10 KND94924.1 - 0.033 12.7 11.9 0.04 12.4 8.3 1.0 1 0 0 1 1 1 0 Daxx Family T6SS_Vgr PF13296.1 KND94924.1 - 0.054 13.3 1.8 0.09 12.6 0.9 1.7 1 1 0 1 1 1 0 Putative type VI secretion system Rhs element Vgr Paf1 PF03985.8 KND94924.1 - 5.4 5.6 12.1 8.6 4.9 8.4 1.2 1 0 0 1 1 1 0 Paf1 SNF2_N PF00176.18 KND94925.1 - 2.4e-82 276.0 1.2 2.4e-82 276.0 0.9 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KND94925.1 - 7e-21 73.9 0.1 2e-20 72.5 0.1 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 KND94925.1 - 8e-19 67.5 2.1 8e-19 67.5 1.4 3.7 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KND94925.1 - 3.3e-18 65.3 0.4 2.7e-16 59.1 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 KND94925.1 - 9.1e-15 54.2 14.3 9.1e-15 54.2 9.9 3.8 4 0 0 4 4 4 1 HSA QLQ PF08880.6 KND94925.1 - 5.9e-10 38.3 5.3 2.1e-09 36.6 3.7 2.0 1 0 0 1 1 1 1 QLQ WD40 PF00400.27 KND94926.1 - 3.1e-16 58.5 19.6 5.6e-05 22.8 0.4 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_N PF14781.1 KND94926.1 - 0.034 13.7 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal PTPLA PF04387.9 KND94927.1 - 4.1e-41 140.1 6.2 6.6e-41 139.4 4.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DIOX_N PF14226.1 KND94927.1 - 9.9e-19 67.9 0.0 2.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND94927.1 - 4.4e-17 62.1 0.0 1e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 KND94927.1 - 3.1e-09 36.9 2.3 3.1e-09 36.9 1.6 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND94927.1 - 0.24 10.9 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PGAP1 PF07819.8 KND94928.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KND94928.1 - 0.0004 20.1 2.3 0.0021 17.8 1.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND94928.1 - 0.00045 20.1 4.0 0.003 17.4 2.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KND94928.1 - 0.0054 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 KND94928.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DnaJ PF00226.26 KND94929.1 - 2.8e-14 52.5 3.4 1.2e-13 50.5 0.1 2.9 3 0 0 3 3 3 1 DnaJ domain DUF3897 PF13036.1 KND94929.1 - 4.5 6.8 10.0 9.6 5.7 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3897) Amidohydro_2 PF04909.9 KND94930.1 - 3.2e-43 148.2 0.1 3.7e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KND94930.1 - 0.0056 15.9 0.0 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 TatD related DNase GCV_T PF01571.16 KND94931.1 - 8.1e-17 61.2 0.0 3.5e-16 59.2 0.0 1.9 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KND94931.1 - 0.0028 17.6 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Sds3 PF08598.6 KND94932.1 - 1.9e-18 66.7 8.9 1.9e-18 66.7 6.2 3.9 2 2 0 2 2 2 1 Sds3-like Acetyltransf_11 PF13720.1 KND94932.1 - 0.88 9.8 3.2 1.2 9.4 0.2 2.5 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Peptidase_M20 PF01546.23 KND94933.1 - 2.5e-09 36.9 0.4 4.3e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND94933.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CoA_binding PF02629.14 KND94934.1 - 6.4e-20 71.4 0.4 1.8e-19 70.0 0.3 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 KND94934.1 - 6.7e-15 54.9 0.8 1.2e-14 54.1 0.6 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KND94934.1 - 4.7e-11 42.4 0.6 1.2e-10 41.1 0.4 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KND94934.1 - 0.002 18.2 0.9 0.0048 17.0 0.2 2.0 2 0 0 2 2 2 1 CoA binding domain DUF1624 PF07786.7 KND94934.1 - 6.9 5.9 18.9 3.9 6.7 8.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1624) DEAD PF00270.24 KND94936.1 - 5.1e-50 169.2 0.0 2.4e-48 163.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND94936.1 - 1.7e-27 95.0 0.0 1.2e-26 92.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KND94936.1 - 0.037 12.4 0.0 0.037 12.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) SRP1_TIP1 PF00660.12 KND94936.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family LMBR1 PF04791.11 KND94936.1 - 0.15 10.5 3.6 0.21 10.1 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MIP-T3 PF10243.4 KND94936.1 - 2 6.7 43.5 2.7 6.3 30.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.10 KND94936.1 - 2.5 6.6 11.1 4.6 5.7 7.7 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dsh_C PF12316.3 KND94936.1 - 5.6 7.0 9.4 12 5.9 6.5 1.6 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Abhydrolase_2 PF02230.11 KND94937.1 - 8.4e-20 71.1 0.0 1.3e-11 44.3 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KND94937.1 - 4.1e-06 26.8 1.4 6.3e-06 26.2 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND94937.1 - 5.4e-06 26.2 0.0 6.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND94937.1 - 0.00041 19.6 0.0 0.0019 17.4 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family AMP-binding PF00501.23 KND94938.1 - 2.7e-75 253.3 0.0 4e-75 252.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KND94938.1 - 1.1e-63 214.5 0.0 1.7e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KND94938.1 - 1.5e-11 44.2 0.0 2.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KND94938.1 - 1.3e-09 38.1 0.0 2.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KND94938.1 - 8.6e-08 33.0 0.0 3.9e-07 30.9 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KND94938.1 - 1e-05 24.4 0.0 1.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND94938.1 - 0.00026 21.0 0.0 0.01 15.8 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding Rnk_N PF14760.1 KND94938.1 - 0.081 13.0 0.9 3.9 7.6 0.1 3.2 3 0 0 3 3 3 0 Rnk N-terminus Polysacc_synt_2 PF02719.10 KND94938.1 - 0.39 9.5 0.0 0.65 8.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Rft-1 PF04506.8 KND94939.1 - 7.8e-91 305.0 0.3 9.6e-91 304.8 0.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.1 KND94939.1 - 0.0048 16.3 21.1 0.0048 16.3 14.6 3.4 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein MFS_1 PF07690.11 KND94940.1 - 4.8e-25 88.0 48.5 6.7e-17 61.2 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1762 PF08574.5 KND94942.1 - 1.7e-08 34.7 9.9 1.7e-08 34.7 6.9 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) GPI-anchored PF10342.4 KND94943.1 - 2.6e-20 72.6 0.2 2.6e-20 72.6 0.1 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GCHY-1 PF02649.9 KND94943.1 - 0.063 12.5 2.0 0.088 12.0 1.4 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 MFS_1 PF07690.11 KND94944.1 - 3.2e-27 95.1 41.3 2.2e-26 92.3 15.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KND94946.1 - 9.1e-61 199.7 15.7 2.1e-11 43.2 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KND94946.1 - 8.8e-07 28.8 0.0 0.00055 19.7 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KND94946.1 - 0.00012 20.4 14.5 0.0063 14.7 0.2 4.2 2 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 KND94946.1 - 0.00042 19.2 1.5 7.7 5.3 0.0 3.9 2 1 2 4 4 4 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 KND94946.1 - 0.0033 16.2 0.0 2.8 6.5 0.0 3.4 3 1 1 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 KND94946.1 - 0.046 13.4 0.0 5.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1777 PF08648.7 KND94946.1 - 1.1 8.9 24.8 1.8 8.2 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Pkinase PF00069.20 KND94947.1 - 9.5e-68 228.1 0.0 2.1e-67 226.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94947.1 - 2.7e-36 125.0 0.0 4.4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94947.1 - 3.4e-07 29.5 0.0 7.1e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND94947.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family His_Phos_2 PF00328.17 KND94948.1 - 8e-08 31.9 0.0 5e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TcpQ PF10671.4 KND94948.1 - 0.012 15.5 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q MFS_1 PF07690.11 KND94949.1 - 7.1e-29 100.6 33.6 7.1e-29 100.6 23.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94949.1 - 1.2e-07 30.7 11.9 1.2e-07 30.7 8.2 3.2 2 2 0 3 3 3 1 Sugar (and other) transporter Prenyltrans PF00432.16 KND94950.1 - 8.5e-56 185.1 7.7 2.6e-12 46.0 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KND94950.1 - 3.8e-34 117.4 0.0 3.4e-12 46.7 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KND94950.1 - 6.1e-09 35.8 0.0 0.00054 19.9 0.0 3.2 2 1 1 3 3 3 2 Prenyltransferase-like Glyco_hydro_76 PF03663.9 KND94952.1 - 1.1e-140 469.2 3.0 1.4e-140 468.9 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4623 PF15416.1 KND94952.1 - 0.021 13.1 0.2 0.034 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) Zn_clus PF00172.13 KND94954.1 - 2.7e-06 27.2 15.3 4.4e-06 26.5 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND94954.1 - 0.00033 19.3 0.1 0.00054 18.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 KND94955.1 - 4.7e-08 32.9 0.3 9.8e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND94955.1 - 3.3e-07 30.3 0.0 6.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND94955.1 - 5.3e-06 26.5 0.2 1.1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RGS PF00615.14 KND94955.1 - 0.0017 18.4 0.0 0.0042 17.1 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Acetyltransf_4 PF13420.1 KND94955.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec20 PF03908.8 KND94955.1 - 6.2 6.5 4.7 4.1 7.1 0.0 2.9 4 0 0 4 4 4 0 Sec20 CinA PF02464.12 KND94956.1 - 6.4e-47 158.8 0.3 7.4e-47 158.6 0.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein UPF0113 PF03657.8 KND94956.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0113) PARP PF00644.15 KND94957.1 - 7.7e-07 28.7 0.1 1e-05 25.0 0.0 2.5 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain FYRN PF05964.9 KND94957.1 - 0.041 13.3 0.9 0.099 12.1 0.1 2.1 2 0 0 2 2 2 0 F/Y-rich N-terminus MFS_1 PF07690.11 KND94958.1 - 3.3e-08 32.6 0.1 4.1e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94958.1 - 0.042 12.4 2.1 0.058 11.9 1.5 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4131 PF13567.1 KND94958.1 - 0.36 10.2 2.8 6 6.2 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tnp_DNA_bind PF14706.1 KND94959.1 - 0.093 12.4 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Transposase DNA-binding DivIVA PF05103.8 KND94960.1 - 0.00016 21.7 20.2 0.13 12.2 3.5 3.4 2 1 1 3 3 3 2 DivIVA protein Tropomyosin PF00261.15 KND94960.1 - 0.002 17.2 3.5 0.002 17.2 2.4 3.3 1 1 2 3 3 3 1 Tropomyosin HR1 PF02185.11 KND94960.1 - 0.042 13.5 0.2 0.042 13.5 0.1 4.8 4 1 0 4 4 4 0 Hr1 repeat DUF3391 PF11871.3 KND94960.1 - 0.29 11.3 9.0 17 5.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) IncA PF04156.9 KND94960.1 - 0.56 9.7 36.9 1.8 8.1 9.3 3.2 1 1 2 3 3 3 0 IncA protein AAA_13 PF13166.1 KND94960.1 - 9.3 4.5 17.5 0.6 8.5 2.2 1.9 1 1 1 2 2 2 0 AAA domain FlxA PF14282.1 KND94960.1 - 9.7 6.1 20.8 0.31 11.0 7.1 3.2 2 1 2 4 4 4 0 FlxA-like protein Pyr_redox_2 PF07992.9 KND94961.1 - 1.7e-26 93.3 2.0 3e-26 92.5 1.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND94961.1 - 1.5e-14 54.1 2.1 3.5e-12 46.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KND94961.1 - 6.7e-13 48.0 0.0 1.6e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KND94961.1 - 5.6e-07 29.8 0.3 0.00055 20.0 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KND94961.1 - 1.7e-06 28.2 0.4 8.7e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 Reductase C-terminal K_oxygenase PF13434.1 KND94961.1 - 3.7e-05 22.8 0.1 0.18 10.6 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.6 KND94961.1 - 0.0017 17.5 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.1 KND94961.1 - 0.0098 16.1 2.0 0.49 10.6 0.1 3.0 3 1 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 KND94961.1 - 0.011 15.5 2.7 6.6 6.4 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KND94961.1 - 0.099 12.6 4.0 0.52 10.3 0.1 2.8 2 0 0 2 2 2 0 TrkA-N domain Cnd2 PF05786.9 KND94962.1 - 1.8e-211 704.5 2.9 2.2e-211 704.2 2.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 tRNA-synt_1b PF00579.20 KND94963.1 - 1.8e-21 76.5 0.4 1.2e-20 73.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Peptidase_S10 PF00450.17 KND94964.1 - 4.2e-124 414.8 1.0 5.2e-124 414.5 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KND94964.1 - 5.6e-06 26.4 0.0 9.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KND94964.1 - 0.0045 16.9 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family ELO PF01151.13 KND94965.1 - 2.5e-80 269.4 8.7 3e-80 269.1 6.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1735 PF08522.5 KND94965.1 - 0.028 14.7 0.3 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) DUF4141 PF13605.1 KND94965.1 - 0.044 12.9 0.0 0.15 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) DUF423 PF04241.10 KND94965.1 - 0.37 10.7 7.7 0.47 10.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) MoaC PF01967.16 KND94966.1 - 7.6e-51 171.3 2.4 1.2e-50 170.7 1.6 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KND94966.1 - 8.3e-36 122.5 0.0 6.4e-35 119.6 0.0 2.3 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KND94966.1 - 3.2e-18 66.4 0.0 5.5e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily FYVE PF01363.16 KND94966.1 - 1.3e-13 50.5 7.1 1.3e-13 50.5 4.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger Fer4_12 PF13353.1 KND94966.1 - 9.4e-05 22.5 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KND94966.1 - 0.00023 21.1 0.6 0.00065 19.7 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain MCM PF00493.18 KND94969.1 - 1.5e-134 448.0 0.0 4e-134 446.6 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KND94969.1 - 8e-24 84.4 0.5 2.6e-23 82.7 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND94969.1 - 6.3e-08 32.0 0.1 8.4e-06 25.0 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND94969.1 - 3.1e-06 26.9 0.0 1.1e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KND94969.1 - 0.00058 20.2 0.3 0.0025 18.1 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KND94969.1 - 0.019 14.5 0.0 0.074 12.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KND94969.1 - 0.074 12.5 0.2 0.68 9.3 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain HEAT_2 PF13646.1 KND94971.1 - 1e-15 57.7 8.0 0.0011 19.2 0.0 6.9 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 KND94971.1 - 5.7e-09 35.3 19.2 0.17 12.0 0.0 10.2 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KND94971.1 - 1.9e-07 31.3 0.8 0.04 14.3 0.0 5.1 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KND94971.1 - 0.00016 21.0 0.5 6.7 5.9 0.0 4.8 4 0 0 4 4 4 2 CLASP N terminal IFRD PF05004.8 KND94971.1 - 0.034 13.2 4.0 0.039 13.0 0.6 2.5 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Transcrip_reg PF01709.15 KND94972.1 - 5.3e-48 163.1 0.0 6.1e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator AalphaY_MDB PF04611.7 KND94972.1 - 0.078 12.8 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region PH_9 PF15410.1 KND94973.1 - 8.7e-09 35.5 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KND94973.1 - 4.6e-06 26.7 0.0 7.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF2360 PF10152.4 KND94973.1 - 0.023 14.9 0.8 0.023 14.9 0.5 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MutS_V PF00488.16 KND94974.1 - 1.8e-83 279.5 0.0 3.6e-83 278.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND94974.1 - 1.6e-40 139.0 1.8 4.2e-40 137.7 1.2 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KND94974.1 - 4.4e-28 97.5 0.0 1.3e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KND94974.1 - 6.5e-12 45.6 0.7 6.9e-10 39.1 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KND94974.1 - 5.8e-07 29.5 0.0 1.9e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV ATP-synt_E PF05680.7 KND94975.1 - 1.2e-23 82.8 0.0 1.6e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.27 KND94976.1 - 6.8e-19 66.9 18.8 1.9e-08 33.8 0.1 7.6 11 0 0 11 11 11 5 WD domain, G-beta repeat Fcf1 PF04900.7 KND94977.1 - 2.6e-25 88.4 0.3 5.4e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.9 KND94977.1 - 0.51 8.3 2.5 0.74 7.7 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PP2C_2 PF13672.1 KND94978.1 - 2e-05 24.0 0.0 3.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KND94978.1 - 0.0012 18.6 0.1 0.0039 16.9 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) VSP PF03302.8 KND94979.1 - 0.00015 20.5 2.1 0.00021 20.0 1.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein NPDC1 PF06809.6 KND94979.1 - 0.0078 15.0 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Herpes_gE PF02480.11 KND94979.1 - 0.025 12.8 0.0 0.038 12.2 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF726 PF05277.7 KND94980.1 - 9e-128 425.9 1.8 1.3e-127 425.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 KND94980.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 KND94980.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase STT3 PF02516.9 KND94981.1 - 5e-115 385.2 36.7 2.2e-108 363.3 23.7 3.0 2 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PH PF00169.24 KND94982.1 - 9.4e-06 25.7 0.0 9.7e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 KND94982.1 - 0.0016 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain UPF0066 PF01980.11 KND94983.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0066 Pkinase PF00069.20 KND94984.1 - 1.8e-63 214.1 0.0 2.8e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94984.1 - 7.9e-29 100.5 0.0 1.3e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KND94984.1 - 1.3e-10 41.2 0.1 3.4e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 KND94984.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE PF01363.16 KND94986.1 - 1.1e-21 76.4 0.3 1.1e-21 76.4 0.2 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KND94986.1 - 6.6e-08 32.2 6.2 6.6e-08 32.2 4.3 3.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KND94986.1 - 0.0048 16.9 3.8 0.0048 16.9 2.7 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND94986.1 - 0.014 15.3 5.9 0.014 15.3 4.1 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KND94986.1 - 0.018 14.9 1.9 0.018 14.9 1.3 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-DHHC PF01529.15 KND94986.1 - 0.023 14.0 1.1 0.067 12.5 0.3 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase Rad50_zn_hook PF04423.9 KND94986.1 - 0.24 10.8 6.1 0.18 11.3 0.2 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-piccolo PF05715.8 KND94986.1 - 0.34 10.9 6.6 1.1 9.2 2.7 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger Elf1 PF05129.8 KND94986.1 - 4 7.1 11.3 2.1 8.1 3.2 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like C2 PF00168.25 KND94987.1 - 5.7e-70 231.2 4.2 7.9e-21 73.6 0.0 5.4 5 0 0 5 5 5 5 C2 domain DUF4429 PF14472.1 KND94987.1 - 0.003 17.8 0.0 0.0085 16.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4429) DUF2404 PF10296.4 KND94987.1 - 0.062 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) ABC_membrane PF00664.18 KND94989.1 - 8.4e-64 215.6 35.8 1.5e-37 129.4 5.5 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KND94989.1 - 1.8e-61 206.4 0.0 1.6e-32 112.6 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KND94989.1 - 4.8e-11 42.3 5.5 0.0019 17.4 1.6 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KND94989.1 - 2.5e-10 40.8 0.0 0.081 12.8 0.0 3.6 3 1 1 4 4 3 3 AAA domain AAA_16 PF13191.1 KND94989.1 - 4.8e-09 36.4 1.3 6.6e-05 22.9 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KND94989.1 - 3.4e-07 29.7 1.0 0.00041 19.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KND94989.1 - 1.2e-06 27.7 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KND94989.1 - 1.6e-05 25.0 4.2 0.055 13.6 0.1 3.8 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 KND94989.1 - 3.5e-05 22.5 0.1 0.049 12.2 0.0 3.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_30 PF13604.1 KND94989.1 - 8.7e-05 22.1 3.7 0.8 9.2 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KND94989.1 - 9.4e-05 23.2 0.1 0.099 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND94989.1 - 0.00014 21.3 0.3 0.64 9.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KND94989.1 - 0.00015 22.1 0.0 0.0094 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KND94989.1 - 0.00025 20.2 0.0 0.17 10.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 KND94989.1 - 0.0016 18.1 0.8 0.11 12.2 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_5 PF07728.9 KND94989.1 - 0.0019 17.9 0.3 2.3 7.9 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KND94989.1 - 0.0048 16.8 0.1 2.2 8.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KND94989.1 - 0.0051 16.6 0.0 0.58 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KND94989.1 - 0.0065 16.3 0.3 0.4 10.6 0.2 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 KND94989.1 - 0.0075 14.8 0.1 0.041 12.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) MobB PF03205.9 KND94989.1 - 0.014 15.1 0.3 0.78 9.4 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KND94989.1 - 0.015 14.7 0.5 0.25 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain PRK PF00485.13 KND94989.1 - 0.019 14.5 0.0 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.20 KND94989.1 - 0.021 14.3 1.6 0.98 8.8 0.0 2.9 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 KND94989.1 - 0.031 14.4 2.7 20 5.3 0.1 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KND94989.1 - 0.032 13.0 0.4 0.74 8.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KND94989.1 - 0.071 13.0 0.1 10 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KND94989.1 - 0.15 12.4 2.9 1.8 8.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 KND94989.1 - 0.22 12.0 1.0 40 4.7 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein UQ_con PF00179.21 KND94990.1 - 9.5e-26 89.9 0.0 1.2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND94990.1 - 1.6e-09 37.6 0.0 4.4e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND94990.1 - 6e-06 26.1 0.0 7.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KND94990.1 - 9.7e-05 22.0 0.1 0.0002 21.0 0.1 1.5 2 0 0 2 2 2 1 UEV domain Pkinase PF00069.20 KND94991.1 - 1.4e-66 224.2 0.2 2.1e-66 223.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND94991.1 - 5.7e-33 114.0 0.1 5.9e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KND94991.1 - 1.3e-05 24.3 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KND94991.1 - 0.012 14.9 0.0 0.039 13.2 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KND94991.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 KND94992.1 - 2.4e-36 125.1 21.9 2.4e-36 125.1 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND94992.1 - 6.3e-13 48.0 6.8 6.3e-13 48.0 4.7 2.9 3 1 1 4 4 4 1 Sugar (and other) transporter Strabismus PF06638.6 KND94992.1 - 0.18 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Strabismus protein Abhydrolase_6 PF12697.2 KND94994.1 - 5.5e-21 75.5 8.3 5.5e-21 75.5 5.8 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND94994.1 - 5.6e-12 45.6 0.7 4.5e-11 42.6 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND94994.1 - 5e-06 26.2 0.1 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KND94994.1 - 3.6e-05 23.5 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase UPF0227 PF05728.7 KND94994.1 - 0.0077 15.9 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Fungal_trans PF04082.13 KND94995.1 - 4.6e-14 51.9 0.1 2e-13 49.8 0.0 1.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KND94995.1 - 3.2e-13 49.1 7.8 3.3e-06 27.1 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND94995.1 - 1.8e-09 37.2 7.9 5.1e-05 23.3 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.13 KND94995.1 - 6.9e-06 25.8 10.1 2.1e-05 24.3 7.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KND94995.1 - 2.6e-05 24.2 6.8 0.0033 17.6 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KND94995.1 - 0.016 15.3 2.3 0.1 12.8 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND94995.1 - 0.05 13.7 4.3 0.22 11.6 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Amidohydro_4 PF13147.1 KND94996.1 - 1.2e-16 61.6 1.7 1.8e-14 54.4 0.8 3.7 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KND94996.1 - 1.8e-09 37.7 1.4 1.7e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KND94996.1 - 3.4e-09 36.4 0.5 2.8e-08 33.4 0.1 2.5 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KND94996.1 - 1.1e-08 34.7 0.4 0.00019 20.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Melibiase PF02065.13 KND94997.1 - 3.3e-11 42.5 0.0 5.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 KND94997.1 - 4.7e-10 39.5 1.4 4.7e-10 39.5 1.0 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 KND94997.1 - 0.034 13.5 0.4 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family Allantoicase PF03561.10 KND94997.1 - 0.067 12.6 0.0 0.62 9.5 0.0 2.3 1 1 0 1 1 1 0 Allantoicase repeat Dus PF01207.12 KND94998.1 - 9.2e-48 162.6 0.4 5.6e-47 160.0 0.3 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 KND94998.1 - 0.0066 15.5 0.0 0.12 11.4 0.0 2.6 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 KND94998.1 - 0.088 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein HTH_Tnp_1 PF01527.15 KND94998.1 - 0.53 10.2 2.7 5.2 7.0 0.0 3.5 4 0 0 4 4 4 0 Transposase ApoO PF09769.4 KND94999.1 - 7.7e-47 158.9 0.5 1.1e-46 158.3 0.0 1.5 2 0 0 2 2 2 1 Apolipoprotein O Nop14 PF04147.7 KND95000.1 - 2.4e-258 859.4 20.9 3e-258 859.1 14.5 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.1 KND95001.1 - 6.7e-18 64.0 2.0 2.7e-17 62.1 1.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KND95001.1 - 6.6e-09 35.4 7.7 1.8e-08 34.0 5.3 1.8 1 1 0 1 1 1 1 G-patch domain SecD-TM1 PF13721.1 KND95001.1 - 0.071 13.3 0.2 0.071 13.3 0.2 1.9 2 0 0 2 2 2 0 SecD export protein N-terminal TM region DUF4484 PF14831.1 KND95001.1 - 1.1 9.2 4.0 0.43 10.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) HSP70 PF00012.15 KND95002.1 - 0.00016 19.7 0.0 0.00038 18.5 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.15 KND95002.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HlyIII PF03006.15 KND95003.1 - 2.1e-50 171.2 13.9 2.5e-50 170.9 9.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related WD40 PF00400.27 KND95004.1 - 0.00022 20.9 0.0 0.71 9.8 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DnaJ PF00226.26 KND95005.1 - 1.8e-21 75.6 4.0 3.7e-21 74.6 2.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KND95005.1 - 4.4e-21 74.5 0.1 3.3e-18 65.3 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KND95005.1 - 1.5e-14 53.7 17.4 2.8e-14 52.9 12.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KND95005.1 - 0.0025 17.4 8.9 0.058 13.0 1.5 2.5 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KND95005.1 - 0.28 10.9 5.9 1.1 9.0 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 KND95005.1 - 0.3 10.9 6.3 2.5 7.9 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.1 KND95005.1 - 1.8 8.8 8.8 48 4.3 6.2 2.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar Opy2 PF09463.5 KND95005.1 - 4.2 7.5 6.9 14 5.8 0.7 3.2 3 0 0 3 3 3 0 Opy2 protein PhnA_Zn_Ribbon PF08274.7 KND95005.1 - 5.5 6.8 6.1 64 3.4 0.1 3.7 4 0 0 4 4 4 0 PhnA Zinc-Ribbon CAP_GLY PF01302.20 KND95006.1 - 1.7e-17 62.8 0.7 3.2e-17 61.9 0.2 1.7 2 0 0 2 2 1 1 CAP-Gly domain Med4 PF10018.4 KND95006.1 - 0.023 14.0 5.5 0.12 11.7 0.5 2.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.10 KND95006.1 - 0.034 13.6 0.3 0.034 13.6 0.2 4.1 4 1 1 5 5 5 0 Septum formation initiator DUF305 PF03713.8 KND95006.1 - 0.082 12.7 4.8 0.26 11.0 3.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF305) Spc7 PF08317.6 KND95006.1 - 0.4 9.3 18.4 1.8 7.1 4.4 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.8 KND95006.1 - 0.63 9.9 12.9 0.14 12.0 0.2 3.3 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.1 KND95006.1 - 0.65 8.3 9.8 0.057 11.8 1.7 2.4 2 1 1 3 3 3 0 AAA domain MscS_porin PF12795.2 KND95006.1 - 1.7 7.9 17.6 0.12 11.6 0.8 3.6 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF812 PF05667.6 KND95006.1 - 2 6.8 18.0 10 4.4 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF812) zf-CCHC_4 PF14392.1 KND95006.1 - 2.6 7.7 3.8 14 5.4 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle PEARLI-4 PF05278.7 KND95006.1 - 2.6 7.3 11.0 9.5 5.4 3.4 2.4 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4140 PF13600.1 KND95006.1 - 2.7 8.5 23.7 2 8.8 0.4 5.4 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.19 KND95006.1 - 5.7 6.6 5.4 9.1 5.9 0.7 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD BLOC1_2 PF10046.4 KND95006.1 - 5.9 7.1 10.2 1.5 9.0 0.9 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.6 KND95006.1 - 7.9 5.9 18.2 0.16 11.4 0.3 3.6 3 1 0 4 4 4 0 Phage minor structural protein GP20 HEAT_2 PF13646.1 KND95007.1 - 9.7e-05 22.5 0.0 0.00041 20.5 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 KND95007.1 - 0.015 15.3 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat DUF658 PF04936.7 KND95007.1 - 0.44 10.3 3.4 0.72 9.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) GLTT PF01744.15 KND95007.1 - 1.2 8.5 4.4 0.45 9.9 1.1 1.7 2 0 0 2 2 2 0 GLTT repeat (6 copies) THF_DHG_CYH PF00763.18 KND95009.1 - 9.9e-19 67.4 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KND95009.1 - 2.4e-13 49.4 0.2 8.7e-09 34.6 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 KND95009.1 - 0.01 14.7 0.1 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle GMC_oxred_N PF00732.14 KND95011.1 - 7.8e-39 133.5 0.7 1.3e-38 132.8 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND95011.1 - 8.8e-29 100.6 0.2 2.8e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND95011.1 - 2e-07 30.2 0.4 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KND95011.1 - 4.4e-07 29.1 6.8 8.1e-06 24.9 4.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND95011.1 - 1.8e-05 24.6 0.2 0.00015 21.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND95011.1 - 1.8e-05 24.6 0.3 0.00027 20.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND95011.1 - 0.0012 18.0 0.6 0.0022 17.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KND95011.1 - 0.0057 15.7 0.3 0.014 14.5 0.2 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KND95011.1 - 0.025 13.0 0.0 0.043 12.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KND95011.1 - 0.53 9.6 1.4 1 8.7 1.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDEase_I PF00233.14 KND95012.1 - 1.5e-41 142.6 4.2 1.8e-39 135.9 0.1 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M16_C PF05193.16 KND95013.1 - 1.5e-33 115.9 0.0 2e-16 60.2 0.0 3.7 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND95013.1 - 6.1e-32 110.4 1.1 1.4e-31 109.3 0.1 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF2202 PF09968.4 KND95013.1 - 0.046 13.3 0.8 0.31 10.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) zf-CCHC_2 PF13696.1 KND95014.1 - 0.011 15.2 0.8 0.021 14.2 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Cytochrome_C554 PF13435.1 KND95014.1 - 0.82 9.7 8.3 2.6 8.1 5.3 2.2 1 1 0 1 1 1 0 Cytochrome c554 and c-prime CDC45 PF02724.9 KND95014.1 - 0.83 7.6 10.4 1.4 6.8 7.2 1.4 1 0 0 1 1 1 0 CDC45-like protein NUDIX_2 PF13869.1 KND95015.1 - 7.2e-76 253.7 0.0 1.8e-59 200.2 0.0 2.1 1 1 1 2 2 2 2 Nucleotide hydrolase UPF0047 PF01894.12 KND95016.1 - 1.5e-39 134.4 0.0 2.4e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 KND95016.1 - 2.4e-14 52.8 0.6 3.8e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KND95016.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb eRF1_2 PF03464.10 KND95017.1 - 7.7e-46 155.7 0.1 1.4e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KND95017.1 - 3.7e-40 136.7 0.4 7.3e-40 135.7 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KND95017.1 - 2e-28 98.5 0.0 4e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF1770 PF08589.5 KND95018.1 - 3.9e-26 91.5 0.7 4.8e-26 91.2 0.5 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF2428 PF10350.4 KND95019.1 - 8.1e-29 100.4 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Peptidase_C27 PF05407.7 KND95019.1 - 0.0016 18.2 0.1 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Rubella virus endopeptidase HEAT PF02985.17 KND95019.1 - 0.0025 17.7 0.2 0.5 10.5 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat DUF2428 PF10350.4 KND95020.1 - 6.6e-29 100.7 0.2 1.2e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KND95020.1 - 1.7e-06 27.6 4.5 0.17 12.0 0.1 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KND95020.1 - 0.0026 18.1 4.2 0.039 14.4 0.1 3.8 3 0 0 3 3 3 1 HEAT-like repeat Tcp11 PF05794.8 KND95020.1 - 0.22 10.1 0.2 0.4 9.3 0.2 1.3 1 0 0 1 1 1 0 T-complex protein 11 DUF3074 PF11274.3 KND95021.1 - 5.9e-56 189.0 0.4 3.1e-54 183.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) PH PF00169.24 KND95021.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KND95021.1 - 0.0044 16.5 0.0 0.0096 15.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain CAF-1_p150 PF11600.3 KND95021.1 - 0.011 15.1 35.3 0.024 14.0 24.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_transf_22 PF03901.12 KND95022.1 - 1.3e-56 192.4 20.5 1.7e-56 192.0 14.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L1 PF00687.16 KND95023.1 - 4.2e-42 143.9 0.3 5e-42 143.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.16 KND95024.1 - 3.2e-74 247.9 0.0 3.5e-74 247.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND95024.1 - 5.1e-14 51.8 0.0 6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KND95024.1 - 5.6e-12 45.0 0.5 3.9e-08 32.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KND95024.1 - 8.6e-12 44.7 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KND95024.1 - 4.4e-09 35.8 0.0 5.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KND95024.1 - 6.3e-09 36.3 0.0 8.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KND95024.1 - 2.6e-06 27.3 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND95024.1 - 5e-06 26.0 0.0 0.00075 18.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KND95024.1 - 0.009 14.8 0.2 0.084 11.6 0.0 2.4 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 KND95024.1 - 0.0096 15.2 0.6 0.043 13.0 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 KND95024.1 - 0.093 13.1 0.2 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Skp1 PF01466.14 KND95025.1 - 1.9e-39 133.5 0.9 4.3e-39 132.4 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KND95025.1 - 1.7e-16 60.0 0.0 3.6e-16 59.0 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KND95025.1 - 0.15 12.0 1.4 0.2 11.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ribosomal_L2_C PF03947.13 KND95027.1 - 1e-36 125.6 3.8 1.4e-36 125.1 2.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KND95027.1 - 3e-08 33.5 0.2 0.00054 19.8 0.1 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, RNA binding domain NRDE-2 PF08424.5 KND95028.1 - 1.4e-79 267.3 0.9 6.1e-78 261.9 0.1 2.6 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KND95028.1 - 0.00019 21.7 1.1 2.4 9.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND95028.1 - 0.0079 16.3 0.1 6.2 7.2 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat adh_short PF00106.20 KND95029.1 - 2.1e-23 83.0 0.2 3e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND95029.1 - 5.1e-13 49.0 0.1 7.8e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND95029.1 - 1.3e-06 28.3 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KND95029.1 - 2.9e-05 24.1 0.7 0.0001 22.3 0.3 2.0 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KND95029.1 - 0.00031 20.4 1.7 0.00059 19.5 0.8 1.9 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 KND95029.1 - 0.00037 20.0 0.1 0.00074 19.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KND95029.1 - 0.00053 19.0 0.0 0.00089 18.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 KND95029.1 - 0.0011 19.4 0.0 0.15 12.5 0.1 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KND95029.1 - 0.0042 16.7 0.1 0.0042 16.7 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KND95029.1 - 0.0083 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KND95029.1 - 0.014 15.5 0.1 0.025 14.6 0.1 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KND95029.1 - 0.033 14.0 0.3 0.079 12.7 0.0 1.8 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 KND95029.1 - 0.061 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KND95029.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 KND95029.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF3669 PF12417.3 KND95030.1 - 2.2e-24 84.9 0.1 3.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Zinc finger protein Inhibitor_Mig-6 PF11555.3 KND95030.1 - 0.03 14.6 1.5 8.5 6.8 0.0 2.2 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 SURF4 PF02077.10 KND95031.1 - 3.4e-97 324.9 6.3 3.9e-97 324.8 4.4 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 KND95031.1 - 1.3 9.2 14.6 0.75 9.9 0.7 2.8 2 1 0 2 2 2 0 Type IV leader peptidase family HhH-GPD PF00730.20 KND95032.1 - 0.00076 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.17 KND95033.1 - 6.4e-19 67.3 0.2 1.6e-18 66.1 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95033.1 - 8.9e-15 54.4 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95033.1 - 4.2e-09 36.1 0.1 6.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWIM PF04434.12 KND95034.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 SWIM zinc finger Pkinase PF00069.20 KND95035.1 - 0.0019 17.3 0.1 0.009 15.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95035.1 - 0.0098 14.9 0.2 0.081 11.9 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Zn_clus PF00172.13 KND95037.1 - 3.9 7.4 12.0 0.13 12.1 3.5 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 KND95038.1 - 4.2e-21 75.7 0.2 6.1e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KND95038.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 CsiD His_Phos_2 PF00328.17 KND95039.1 - 7.1e-39 134.1 0.0 8.5e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DSPn PF14671.1 KND95040.1 - 8.1e-42 142.5 0.0 4.1e-39 133.7 0.0 3.1 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KND95040.1 - 3e-16 59.2 0.0 6.9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KND95040.1 - 9.8e-07 28.3 0.3 2.9e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase HeLo PF14479.1 KND95041.1 - 7.3e-43 146.7 0.4 2e-42 145.3 0.1 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation ketoacyl-synt PF00109.21 KND95042.1 - 2.6e-58 197.4 5.1 2.6e-58 197.4 3.6 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KND95042.1 - 1e-35 122.1 3.8 1.2e-35 121.9 1.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KND95042.1 - 9.2e-05 21.5 0.1 0.00019 20.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GPI-anchored PF10342.4 KND95043.1 - 1.3e-12 48.0 3.7 1.3e-12 48.0 2.6 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 KND95043.1 - 1.8 6.7 16.2 2 6.6 11.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF966 PF06136.8 KND95043.1 - 2.4 7.5 12.4 2.6 7.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4551 PF15087.1 KND95043.1 - 3.4 5.9 5.4 4.5 5.5 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tmemb_cc2 PF10267.4 KND95043.1 - 6.3 5.2 13.2 8 4.9 9.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Rifin_STEVOR PF02009.11 KND95043.1 - 7.4 6.1 7.2 9.7 5.7 5.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family TFIIA PF03153.8 KND95043.1 - 7.5 6.3 11.5 8 6.2 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_viral_N PF00242.12 KND95043.1 - 9 5.2 16.8 12 4.8 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DNA_ligase_ZBD PF03119.11 KND95044.1 - 0.16 11.6 2.9 0.3 10.8 2.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain VP_N-CPKC PF11475.3 KND95044.1 - 3 7.4 5.7 3.6 7.1 1.1 2.2 2 0 0 2 2 2 0 Virion protein N terminal domain UDPGP PF01704.13 KND95046.1 - 2.1e-185 616.2 0.1 2.4e-185 616.0 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Phage_prot_Gp6 PF05133.9 KND95046.1 - 0.033 12.7 0.1 0.054 12.0 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like DUF4301 PF14134.1 KND95046.1 - 0.033 12.7 0.2 0.72 8.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4301) Leo1 PF04004.8 KND95047.1 - 1.2e-27 96.6 2.2 1.6e-27 96.2 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 KND95048.1 - 2.6e-38 131.4 1.3 6.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Methyltransf_26 PF13659.1 KND95049.1 - 1.9e-18 66.6 0.1 2.6e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND95049.1 - 0.00022 20.6 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cullin PF00888.17 KND95050.1 - 1.7e-128 429.7 4.9 2.2e-128 429.4 3.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KND95050.1 - 9e-16 57.4 0.3 3.6e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain SWIM PF04434.12 KND95051.1 - 0.071 12.6 0.4 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 SWIM zinc finger LSM PF01423.17 KND95052.1 - 2.8e-17 62.0 0.0 3.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND95052.1 - 0.00021 21.1 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain HlyD_3 PF13437.1 KND95052.1 - 0.059 13.7 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF3247 PF11607.3 KND95052.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) AP_endonuc_2 PF01261.19 KND95053.1 - 0.021 14.1 0.1 0.069 12.4 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Ctr PF04145.10 KND95054.1 - 1.3e-37 129.0 3.9 1.6e-37 128.7 2.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3144 PF11342.3 KND95054.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) DUF4131 PF13567.1 KND95054.1 - 10 5.5 6.6 5.6 6.3 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) NUDIX PF00293.23 KND95055.1 - 6.7e-12 45.1 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain FAA_hydrolase PF01557.13 KND95056.1 - 8.9e-53 178.9 0.0 1.1e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.7 KND95057.1 - 1e-58 197.0 0.0 1.1e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KND95057.1 - 1.9e-05 24.0 0.1 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KND95057.1 - 7.4e-05 22.4 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DUF4095 PF13338.1 KND95057.1 - 0.059 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) DZR PF12773.2 KND95057.1 - 0.068 13.0 0.5 0.15 11.9 0.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon EXS PF03124.9 KND95059.1 - 6e-104 347.7 3.7 6.8e-104 347.6 2.5 1.0 1 0 0 1 1 1 1 EXS family DUF2346 PF09803.4 KND95060.1 - 0.00078 19.2 9.0 0.0024 17.6 5.1 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2346) Complex1_LYR_1 PF13232.1 KND95060.1 - 0.06 13.5 1.8 0.083 13.1 1.3 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Phospholamban PF04272.9 KND95061.1 - 0.33 10.4 0.1 0.78 9.2 0.1 1.6 1 0 0 1 1 1 0 Phospholamban Nnf1 PF03980.9 KND95062.1 - 2.8e-26 91.6 0.2 7e-26 90.3 0.1 1.7 2 0 0 2 2 2 1 Nnf1 DUF1908 PF08926.6 KND95062.1 - 0.044 12.5 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Sigma70_ner PF04546.8 KND95062.1 - 0.045 13.3 4.8 0.2 11.2 0.4 2.4 3 0 0 3 3 3 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KND95062.1 - 0.12 12.6 2.1 0.22 11.8 1.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PCP PF02429.10 KND95062.1 - 0.12 12.4 1.3 0.39 10.8 0.7 1.8 2 0 0 2 2 2 0 Peridinin-chlorophyll A binding protein DUF1640 PF07798.6 KND95063.1 - 3.3e-12 46.8 5.9 5.8e-12 45.9 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1191 PF06697.7 KND95063.1 - 0.067 11.9 0.3 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Phage_connect_1 PF05135.8 KND95063.1 - 0.1 12.7 0.6 0.19 11.9 0.1 1.7 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein SpoIIIAH PF12685.2 KND95063.1 - 0.32 10.4 0.0 0.32 10.4 0.0 3.5 2 1 0 2 2 2 0 SpoIIIAH-like protein PUF PF00806.14 KND95064.1 - 2.3e-60 196.8 9.2 1.8e-07 30.2 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 KND95064.1 - 0.12 12.6 0.9 12 6.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF260 SKG6 PF08693.5 KND95065.1 - 2.9 7.2 4.5 7.1 6.0 3.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zn_clus PF00172.13 KND95066.1 - 6.3e-13 48.3 29.4 3.8e-08 33.1 8.0 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND95066.1 - 4.8e-05 22.3 0.0 7.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haem_bd PF14376.1 KND95066.1 - 0.89 9.2 4.1 1.9 8.1 2.8 1.5 1 0 0 1 1 1 0 Haem-binding domain zf-C2H2 PF00096.21 KND95068.1 - 2e-07 30.9 21.9 9.7e-06 25.6 2.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND95068.1 - 7.6e-05 22.8 4.4 7.6e-05 22.8 3.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KND95068.1 - 0.00036 20.5 1.0 0.00099 19.1 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KND95068.1 - 0.00044 20.3 1.1 0.00044 20.3 0.8 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 KND95068.1 - 0.029 14.5 3.5 0.14 12.3 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ARS2 PF04959.8 KND95068.1 - 0.075 13.2 0.9 0.95 9.6 0.7 2.6 2 0 0 2 2 2 0 Arsenite-resistance protein 2 DUF629 PF04780.7 KND95068.1 - 0.13 10.7 2.9 8.3 4.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-TRAF PF02176.13 KND95068.1 - 0.24 11.8 7.6 0.13 12.6 2.3 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 KND95068.1 - 2.3 8.3 8.3 7.2 6.7 4.3 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) NTF2 PF02136.15 KND95069.1 - 5.1e-24 84.9 0.8 8.3e-24 84.2 0.6 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KND95069.1 - 1.9e-07 30.6 0.0 3.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95069.1 - 2.5e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95069.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KND95069.1 - 0.093 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif PAT1 PF09770.4 KND95069.1 - 2.4 6.2 18.1 3.4 5.7 12.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 KND95070.1 - 8e-54 181.3 0.0 8.3e-43 145.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KND95070.1 - 1e-23 83.1 0.2 2.3e-23 82.0 0.2 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KND95070.1 - 9.3e-09 35.5 10.1 3.1e-05 24.0 0.0 4.3 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 KND95070.1 - 1.1e-07 31.9 0.5 0.0015 18.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KND95070.1 - 3.7e-07 30.9 0.3 0.03 15.1 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KND95070.1 - 9.2e-07 29.2 0.6 0.001 19.3 0.2 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KND95070.1 - 9.5e-07 28.6 0.2 0.00085 19.0 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 KND95070.1 - 5.1e-06 26.5 0.0 0.00077 19.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KND95070.1 - 1.4e-05 24.9 0.0 0.042 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KND95070.1 - 1.4e-05 24.9 0.4 0.37 10.6 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KND95070.1 - 2.1e-05 24.2 0.1 0.076 12.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KND95070.1 - 2.8e-05 23.2 0.0 0.044 12.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.7 KND95070.1 - 3.1e-05 23.1 0.0 0.019 14.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KND95070.1 - 0.00015 21.4 0.1 0.74 9.6 0.0 3.4 3 0 0 3 3 2 2 Part of AAA domain UPF0079 PF02367.12 KND95070.1 - 0.00078 19.0 0.1 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 KND95070.1 - 0.0016 18.3 0.1 0.55 10.0 0.1 2.5 2 0 0 2 2 2 1 Shikimate kinase TIP49 PF06068.8 KND95070.1 - 0.0023 16.7 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 KND95070.1 - 0.0023 17.1 0.2 0.96 8.5 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KND95070.1 - 0.0025 17.2 0.0 0.087 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 KND95070.1 - 0.0029 17.3 0.0 1.4 8.5 0.0 3.7 3 1 1 4 4 4 1 Archaeal ATPase IstB_IS21 PF01695.12 KND95070.1 - 0.0034 16.8 0.2 1.9 7.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KND95070.1 - 0.0037 17.4 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 KND95070.1 - 0.0041 17.0 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KND95070.1 - 0.0072 16.2 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KND95070.1 - 0.017 14.2 0.3 4.4 6.3 0.0 2.8 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.17 KND95070.1 - 0.018 13.9 0.1 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 KND95070.1 - 0.018 14.4 5.1 2.7 7.3 0.1 4.3 3 2 0 4 4 4 0 AAA domain AAA_24 PF13479.1 KND95070.1 - 0.037 13.6 1.5 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KND95070.1 - 0.04 14.1 0.1 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.15 KND95070.1 - 0.064 12.9 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.8 KND95070.1 - 0.066 12.1 0.0 0.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.5 KND95070.1 - 0.13 11.4 0.1 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KND95070.1 - 0.15 11.7 0.1 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 KND95070.1 - 0.21 10.8 0.1 18 4.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Cytidylate_kin2 PF13189.1 KND95070.1 - 0.22 11.4 0.0 28 4.5 0.0 2.6 2 1 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.7 KND95070.1 - 0.25 10.8 0.0 1.9 7.9 0.0 2.4 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 KND95070.1 - 0.43 9.5 0.1 2.2 7.1 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.12 KND95070.1 - 0.51 9.1 0.0 31 3.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Inositol_P PF00459.20 KND95071.1 - 2.5e-40 138.4 0.5 4.1e-40 137.7 0.3 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family RRS1 PF04939.7 KND95074.1 - 5e-59 198.4 1.7 5.8e-59 198.2 1.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 KND95075.1 - 3.7e-29 101.2 0.0 6e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DAP3 PF10236.4 KND95076.1 - 3.5e-85 285.6 0.0 4.4e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SET PF00856.23 KND95077.1 - 7.1e-08 32.9 0.0 0.0087 16.3 0.0 3.1 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 KND95077.1 - 0.0046 16.5 0.5 2.8 7.6 0.1 2.7 2 0 0 2 2 2 2 TPR repeat FG-GAP PF01839.18 KND95077.1 - 0.057 13.1 0.6 10 5.9 0.1 2.5 2 0 0 2 2 2 0 FG-GAP repeat TPR_14 PF13428.1 KND95077.1 - 0.19 12.4 7.3 14 6.6 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KND95077.1 - 4.9 7.9 8.9 1.9 9.2 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat KH_1 PF00013.24 KND95078.1 - 1.1e-37 127.4 12.6 3.8e-14 52.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KND95078.1 - 1.4e-29 101.1 13.3 9.6e-11 41.0 0.6 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KND95078.1 - 8.6e-09 34.8 9.6 0.022 14.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KND95078.1 - 7.4e-07 28.7 8.2 0.061 12.9 0.1 3.8 3 1 0 3 3 3 3 KH domain KH_5 PF13184.1 KND95078.1 - 0.00079 19.1 4.4 1 9.2 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KND95078.1 - 0.012 15.0 0.5 0.78 9.2 0.0 3.1 3 0 0 3 3 3 0 dUTPase bZIP_1 PF00170.16 KND95079.1 - 7.7e-09 35.3 14.0 3.3e-08 33.3 8.0 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KND95079.1 - 9.9e-07 28.4 8.8 9.9e-07 28.4 6.1 2.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 KND95079.1 - 5.3e-05 23.4 13.8 0.00013 22.1 9.2 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor Endotoxin_N PF03945.9 KND95079.1 - 0.013 14.8 2.4 0.028 13.7 1.7 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF342 PF03961.8 KND95079.1 - 0.56 8.5 9.2 0.83 8.0 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KND95079.1 - 2.6 7.6 13.0 5.1 6.6 9.0 1.5 1 0 0 1 1 1 0 IncA protein Sel1 PF08238.7 KND95080.1 - 8.8e-11 42.0 6.0 0.1 13.2 0.0 5.6 5 0 0 5 5 5 3 Sel1 repeat UPF0731 PF14982.1 KND95081.1 - 0.0096 15.8 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 UPF0731 family Toxin_67 PF15545.1 KND95081.1 - 0.11 12.4 0.2 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Putative toxin 67 Sensor PF13796.1 KND95081.1 - 0.87 9.1 4.5 0.65 9.5 0.2 2.2 2 0 0 2 2 2 0 Putative sensor SecA_DEAD PF07517.9 KND95082.1 - 3 7.0 10.5 0.13 11.4 2.6 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain CorA PF01544.13 KND95085.1 - 0.00025 20.1 0.7 0.00025 20.1 0.5 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein LMBR1 PF04791.11 KND95087.1 - 1.6e-27 96.2 8.0 3.4e-27 95.1 5.5 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein P5CR_dimer PF14748.1 KND95088.1 - 8.5e-31 106.1 1.7 1.5e-30 105.3 1.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KND95088.1 - 8.5e-12 45.3 0.4 3.2e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF2040 PF09745.4 KND95089.1 - 1.3e-38 131.7 23.1 1.3e-38 131.7 16.0 3.3 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) CPSF_A PF03178.10 KND95090.1 - 1.9e-95 319.6 0.0 2e-94 316.2 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KND95090.1 - 1.6e-61 208.0 0.0 2.6e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 KND95090.1 - 0.015 15.1 0.1 0.048 13.5 0.1 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF1945 PF09178.5 KND95090.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) Lectin_leg-like PF03388.8 KND95091.1 - 2.8e-66 222.9 0.0 3.8e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KND95091.1 - 0.0041 16.5 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-HC5HC2H_2 PF13832.1 KND95094.1 - 7.7e-18 64.5 2.0 7.7e-18 64.5 1.4 4.1 3 1 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.13 KND95094.1 - 2.4e-13 49.8 0.0 4.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 KND95094.1 - 5.1e-13 48.9 3.5 5.1e-13 48.9 2.4 4.7 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 KND95094.1 - 8.1e-10 38.2 24.5 2.2e-06 27.2 6.4 6.1 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.1 KND95094.1 - 1.2e-08 34.1 4.4 1.2e-08 34.1 3.1 4.8 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.17 KND95094.1 - 0.0022 17.6 1.7 0.0022 17.6 1.1 5.4 5 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.26 KND95094.1 - 0.005 16.8 0.2 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain ELM2 PF01448.19 KND95094.1 - 0.049 14.2 2.9 1.3 9.7 2.0 2.6 1 1 0 1 1 1 0 ELM2 domain Abhydrolase_6 PF12697.2 KND95095.1 - 5.6e-10 39.4 0.5 5.2e-09 36.3 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND95095.1 - 3.9e-08 33.1 0.1 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND95095.1 - 1.3e-06 28.2 0.0 1.3e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 KND95095.1 - 0.0014 17.3 0.0 0.0022 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KND95095.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KND95095.1 - 0.037 13.4 0.0 0.16 11.3 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pil1 PF13805.1 KND95096.1 - 1.1e-104 349.4 0.2 1.1e-104 349.4 0.2 2.1 3 0 0 3 3 3 1 Eisosome component PIL1 Pyrophosphatase PF00719.14 KND95096.1 - 4.8e-51 172.2 0.2 7.3e-51 171.6 0.1 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 KND95097.1 - 7.5e-21 73.8 1.2 1.1e-20 73.3 0.8 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 KND95098.1 - 4.7e-17 61.4 0.9 2e-15 56.2 0.1 2.8 3 0 0 3 3 3 1 Sec20 STAT_alpha PF01017.15 KND95098.1 - 0.0095 15.6 4.6 0.094 12.4 0.2 3.1 2 2 1 3 3 3 2 STAT protein, all-alpha domain Aldolase_II PF00596.16 KND95099.1 - 2.4e-35 121.8 0.0 3.1e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LcnG-beta PF11632.3 KND95099.1 - 0.079 12.7 1.3 0.19 11.4 0.9 1.6 1 0 0 1 1 1 0 Lactococcin G-beta Hexokinase_2 PF03727.11 KND95100.1 - 5.8e-89 297.4 0.0 7.7e-89 297.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KND95100.1 - 3.8e-74 248.4 0.0 3.8e-73 245.2 0.0 2.0 2 0 0 2 2 2 1 Hexokinase Ank_2 PF12796.2 KND95101.1 - 0.0017 18.6 0.0 0.011 16.1 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ribophorin_I PF04597.9 KND95102.1 - 5.4e-146 486.5 0.1 6.1e-146 486.3 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Innate_immun PF12782.2 KND95103.1 - 7.5 5.6 8.1 7.3 5.7 5.6 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Pkinase PF00069.20 KND95105.1 - 3.2e-18 65.8 0.0 3.5e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95105.1 - 1.1e-08 34.4 0.0 6.4e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase GSH_synth_ATP PF03917.12 KND95106.1 - 2.3e-97 325.8 0.0 8.6e-97 324.0 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KND95106.1 - 2e-31 108.2 0.0 3.3e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 KND95107.1 - 2.9e-41 141.2 0.0 4.8e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND95107.1 - 8.4e-18 64.0 0.2 1e-16 60.5 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TAP_C PF03943.8 KND95109.1 - 1e-13 50.4 0.4 2.3e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 KND95109.1 - 1.5e-07 30.8 0.0 0.00025 20.5 0.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KND95109.1 - 6.4e-05 23.3 0.0 0.00042 20.6 0.0 2.3 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 KND95109.1 - 0.016 15.1 0.0 0.49 10.6 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 KND95109.1 - 0.071 12.8 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat Ank_2 PF12796.2 KND95110.1 - 1.1e-55 185.8 0.5 4e-14 52.7 0.0 9.0 4 3 4 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 KND95110.1 - 7.9e-38 126.4 21.8 4.6e-06 26.1 0.0 13.0 16 0 0 16 16 16 7 Ankyrin repeat Ank_4 PF13637.1 KND95110.1 - 1.9e-37 126.9 2.5 2.5e-06 27.8 0.0 10.9 8 3 3 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND95110.1 - 7.1e-36 118.6 7.6 0.00028 20.8 0.0 14.2 16 0 0 16 16 16 7 Ankyrin repeat Ank_5 PF13857.1 KND95110.1 - 1.4e-33 114.1 4.2 0.02 15.1 0.0 11.6 11 1 1 12 12 12 7 Ankyrin repeats (many copies) DUF1772 PF08592.6 KND95111.1 - 3.5 7.3 11.4 0.26 11.0 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) HpaP PF09483.5 KND95111.1 - 7.7 6.4 10.0 5.6 6.8 3.4 2.1 2 0 0 2 2 2 0 Type III secretion protein (HpaP) HMG_box_2 PF09011.5 KND95112.1 - 2.8e-05 24.4 0.1 2.8e-05 24.4 0.1 2.2 3 0 0 3 3 3 1 HMG-box domain HMG_box PF00505.14 KND95112.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Cpn60_TCP1 PF00118.19 KND95113.1 - 1.7e-140 468.9 2.9 1.9e-140 468.7 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family XPC-binding PF09280.6 KND95114.1 - 2e-23 81.5 13.1 3.5e-23 80.8 9.1 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KND95114.1 - 1.1e-19 69.6 6.8 3.1e-09 36.3 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KND95114.1 - 1.6e-19 69.0 0.1 2.5e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KND95114.1 - 1.5e-08 34.2 0.1 2.7e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KND95114.1 - 0.0009 18.7 0.0 0.83 9.2 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.1 KND95114.1 - 0.00092 19.6 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain DUF2407 PF10302.4 KND95114.1 - 0.01 15.9 0.0 0.027 14.6 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KND95114.1 - 0.039 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KND95114.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain eIF-5a PF01287.15 KND95114.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold BRE1 PF08647.6 KND95115.1 - 3e-27 94.4 11.0 3e-27 94.4 7.6 6.8 4 3 3 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 KND95115.1 - 1.1e-08 34.6 8.1 1.7e-08 33.9 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND95115.1 - 2e-08 34.0 10.1 3.6e-08 33.2 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND95115.1 - 2.6e-08 33.4 11.0 4.6e-08 32.5 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND95115.1 - 1.5e-06 27.7 10.4 2.6e-06 27.0 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KND95115.1 - 1.7e-06 27.7 7.5 3.3e-06 26.8 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KND95115.1 - 0.00045 19.8 6.3 0.0012 18.5 4.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger RolB_RolC PF02027.12 KND95115.1 - 0.00069 18.8 0.1 0.0071 15.5 0.0 2.7 2 0 0 2 2 2 1 RolB/RolC glucosidase family Prok-RING_4 PF14447.1 KND95115.1 - 0.002 17.6 2.9 0.0038 16.7 2.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 KND95115.1 - 0.0026 17.5 2.3 0.0056 16.4 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Phage_GP20 PF06810.6 KND95115.1 - 0.0028 17.1 10.3 0.0028 17.1 7.1 7.1 2 1 6 8 8 7 1 Phage minor structural protein GP20 zf-C3HC4_4 PF15227.1 KND95115.1 - 0.0064 16.3 7.0 0.012 15.4 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KND95115.1 - 0.13 11.8 7.0 0.38 10.3 4.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 KND95115.1 - 1.2 9.0 11.1 9.2 6.2 7.6 2.2 1 1 1 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.2 KND95115.1 - 2.1 8.5 12.2 0.25 11.4 4.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger Retrotrans_gag PF03732.12 KND95115.1 - 2.3 8.3 9.9 2.5 8.2 0.1 4.0 3 0 0 3 3 3 0 Retrotransposon gag protein Reo_sigmaC PF04582.7 KND95115.1 - 8.5 5.4 27.6 0.11 11.6 3.0 4.2 1 1 4 5 5 5 0 Reovirus sigma C capsid protein Myb_DNA-binding PF00249.26 KND95117.1 - 4.3e-05 23.4 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND95117.1 - 0.088 12.9 0.0 0.088 12.9 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain U3_snoRNA_assoc PF08297.6 KND95118.1 - 5.6e-08 32.9 1.8 5.6e-08 32.9 1.3 3.4 3 1 0 3 3 3 1 U3 snoRNA associated DUF4051 PF13260.1 KND95118.1 - 0.67 9.3 3.4 2.8 7.3 2.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) TPR_11 PF13414.1 KND95119.1 - 3e-07 29.9 0.6 4.9e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 KND95119.1 - 8.2e-07 29.2 0.6 0.00012 22.3 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND95119.1 - 1.4e-06 28.8 8.1 0.0074 16.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KND95119.1 - 1.4e-06 28.1 0.7 0.082 13.3 0.0 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND95119.1 - 1.5e-06 27.6 0.5 0.031 14.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KND95119.1 - 2.3e-05 24.4 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KND95119.1 - 9.4e-05 22.2 0.1 0.00087 19.1 0.1 2.6 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KND95119.1 - 0.00011 22.4 7.2 0.064 13.9 0.4 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND95119.1 - 0.0088 15.7 1.6 5.6 7.0 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND95119.1 - 0.043 13.4 0.0 4.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND95119.1 - 0.22 12.0 4.0 21 5.8 0.1 3.5 5 0 0 5 5 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 KND95119.1 - 0.24 11.7 1.6 9.1 6.8 0.0 3.6 4 0 0 4 4 3 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 KND95119.1 - 0.94 9.5 6.7 8 6.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PH_10 PF15411.1 KND95120.1 - 3e-27 95.1 0.0 5.4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KND95120.1 - 9.6e-11 41.6 0.0 3.1e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KND95120.1 - 8.8e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KND95120.1 - 1.4e-07 31.2 6.1 2.5e-07 30.4 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KND95120.1 - 0.00099 18.7 5.2 0.0017 18.0 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KND95120.1 - 0.0033 17.4 1.2 0.0066 16.5 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND95120.1 - 0.038 14.0 5.2 0.07 13.1 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND95120.1 - 0.082 12.5 5.6 0.15 11.7 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 KND95120.1 - 0.16 11.8 0.6 0.46 10.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 KND95120.1 - 1 9.3 4.5 2 8.4 3.1 1.5 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.20 KND95122.1 - 1.4e-71 240.6 0.0 1.8e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95122.1 - 2.7e-31 108.5 0.0 3.5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KND95122.1 - 8e-14 51.8 0.5 3.4e-13 49.8 0.3 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KND95122.1 - 2.6e-10 39.7 0.0 5.1e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND95122.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KND95122.1 - 0.05 13.1 0.1 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KND95122.1 - 0.098 11.9 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DOMON PF03351.12 KND95123.1 - 1.2e-06 28.5 0.1 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 KND95123.1 - 1.8e-06 27.4 5.3 1.8e-06 27.4 3.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) RseC_MucC PF04246.7 KND95123.1 - 6.9 6.2 8.9 1 8.9 1.9 2.8 2 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DOMON PF03351.12 KND95124.1 - 1.2e-06 28.5 0.1 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 KND95124.1 - 1.8e-06 27.4 5.3 1.8e-06 27.4 3.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) RseC_MucC PF04246.7 KND95124.1 - 6.9 6.2 8.9 1 8.9 1.9 2.8 2 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC SUZ PF12752.2 KND95125.1 - 5.2e-05 23.6 1.3 5.2e-05 23.6 0.9 3.5 3 1 0 3 3 3 1 SUZ domain U1snRNP70_N PF12220.3 KND95125.1 - 0.17 12.2 7.4 0.054 13.8 1.1 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SUZ-C PF12901.2 KND95125.1 - 1.5 8.4 13.3 0.26 10.9 4.3 2.6 2 0 0 2 2 2 0 SUZ-C motif Fe_hyd_lg_C PF02906.9 KND95128.1 - 1.8e-59 201.3 0.0 5e-59 199.9 0.0 1.8 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.1 KND95130.1 - 3.9e-07 30.0 10.6 4.9e-06 26.5 0.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KND95130.1 - 6.1e-05 23.1 0.5 6.1e-05 23.1 0.4 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND95130.1 - 0.00023 21.2 0.4 0.00023 21.2 0.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND95130.1 - 0.12 12.5 3.6 1.3 9.2 0.5 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3306 PF11748.3 KND95130.1 - 2.5 8.7 5.3 1.7 9.3 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Pro_isomerase PF00160.16 KND95131.1 - 8e-50 169.0 0.1 1.8e-49 167.9 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KND95131.1 - 2.2e-16 59.0 0.2 7.7e-08 31.9 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat DAHP_synth_1 PF00793.15 KND95132.1 - 8.5e-97 323.0 0.1 1e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COBRA1 PF06209.8 KND95132.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) OPT PF03169.10 KND95134.1 - 3.6e-117 392.3 32.9 1.5e-55 188.7 2.9 3.0 3 0 0 3 3 3 3 OPT oligopeptide transporter protein CcmD PF04995.9 KND95134.1 - 0.0039 16.8 0.9 0.028 14.1 0.0 2.8 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) RAMP4 PF06624.7 KND95134.1 - 3.3 7.3 4.6 2.2 7.8 0.4 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 His_biosynth PF00977.16 KND95135.1 - 1.6e-34 119.2 0.0 1.9e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KND95135.1 - 0.044 12.8 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Aldolase PF01081.14 KND95135.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase Cmc1 PF08583.5 KND95136.1 - 3.2e-15 55.6 4.1 3.7e-15 55.4 2.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like WASH_WAHD PF11945.3 KND95136.1 - 0.03 13.6 0.1 0.03 13.6 0.1 1.0 1 0 0 1 1 1 0 WAHD domain of WASH complex Gemini_AL2 PF01440.11 KND95136.1 - 0.046 13.8 0.2 0.055 13.5 0.2 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein Tmemb_14 PF03647.8 KND95137.1 - 6.7e-19 68.0 2.3 9.1e-19 67.6 1.6 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C CBFD_NFYB_HMF PF00808.18 KND95138.1 - 3.3e-07 30.2 0.4 6.7e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone bZIP_1 PF00170.16 KND95139.1 - 0.019 14.8 8.6 0.051 13.5 5.9 1.7 1 1 0 1 1 1 0 bZIP transcription factor RRN3 PF05327.6 KND95140.1 - 2.4e-162 540.9 0.0 3.7e-162 540.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 MinE PF03776.9 KND95140.1 - 0.11 12.0 0.5 0.24 10.9 0.4 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE AA_permease_2 PF13520.1 KND95141.1 - 1e-28 100.1 25.1 1.2e-28 99.8 17.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND95141.1 - 5.8e-10 38.1 22.8 1.8e-09 36.4 15.8 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND95142.1 - 2.7e-06 26.1 13.0 3.6e-06 25.7 9.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND95142.1 - 0.00013 20.4 10.7 0.00017 20.1 7.4 1.1 1 0 0 1 1 1 1 Amino acid permease GBP_PSP PF02425.10 KND95142.1 - 0.037 13.5 0.1 0.14 11.6 0.0 2.0 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Pinin_SDK_memA PF04696.8 KND95143.1 - 2.1e-23 82.3 18.3 3.4e-23 81.6 12.7 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Ndc1_Nup PF09531.5 KND95143.1 - 9.1 4.5 6.5 14 3.9 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PHF5 PF03660.9 KND95144.1 - 1.6e-51 172.8 10.6 1.9e-51 172.6 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KND95144.1 - 1.1 9.1 15.8 19 5.1 10.1 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 KND95144.1 - 1.4 8.6 15.7 3 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 KND95144.1 - 4.4 4.8 5.8 4.3 4.8 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 KND95144.1 - 7.1 6.4 15.4 0.21 11.2 4.5 2.5 1 1 1 2 2 2 0 PHD-finger Pro-rich_19 PF15455.1 KND95145.1 - 0.00024 20.2 1.4 0.00035 19.7 1.0 1.2 1 0 0 1 1 1 1 Proline-rich 19 MAP7 PF05672.6 KND95145.1 - 0.27 10.6 28.7 0.58 9.5 19.9 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF572 PF04502.8 KND95145.1 - 0.44 9.7 15.1 0.7 9.0 10.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) OmpH PF03938.9 KND95145.1 - 0.46 10.4 7.7 0.82 9.5 5.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1451 PF07295.6 KND95145.1 - 1 9.0 7.6 1.9 8.2 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Pex26 PF07163.7 KND95145.1 - 1.1 8.1 10.4 0.58 9.0 3.6 2.6 2 1 0 2 2 2 0 Pex26 protein DUF3635 PF12330.3 KND95146.1 - 3.8e-06 26.8 0.2 0.00015 21.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Ecl1 PF12855.2 KND95147.1 - 7.2e-12 44.4 3.6 1.1e-11 43.7 2.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 KND95147.1 - 0.0064 15.7 3.1 0.011 14.9 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF581) DUF329 PF03884.9 KND95147.1 - 0.031 13.8 1.2 0.058 12.9 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-MYND PF01753.13 KND95147.1 - 0.058 13.2 1.6 0.13 12.1 1.1 1.6 1 0 0 1 1 1 0 MYND finger C1_1 PF00130.17 KND95147.1 - 0.19 11.4 1.9 0.34 10.6 1.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) E1-E2_ATPase PF00122.15 KND95148.1 - 7.9e-22 77.4 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KND95148.1 - 3e-17 63.4 0.2 8.5e-17 61.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND95148.1 - 2.3e-13 51.0 1.9 4.4e-12 46.8 1.3 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND95148.1 - 8.7e-11 41.6 0.0 2.5e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND95148.1 - 0.0021 17.7 0.4 0.0097 15.5 0.1 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 KND95149.1 - 2.4e-24 86.4 0.0 3.9e-24 85.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND95149.1 - 3.1e-11 43.2 0.0 5.8e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND95149.1 - 5.6e-10 39.1 0.0 1.5e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 KND95151.1 - 2e-09 37.6 0.0 4.5e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND95151.1 - 6e-06 25.8 0.0 9.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND95151.1 - 0.0092 14.7 0.0 0.019 13.6 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KND95151.1 - 0.08 12.8 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase SIR2 PF02146.12 KND95153.1 - 1.5e-24 86.7 0.0 4.7e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Sir2 family LSM PF01423.17 KND95154.1 - 3.8e-17 61.6 0.1 4.7e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND95154.1 - 0.00013 21.7 0.1 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain SPAN PF02510.9 KND95154.1 - 0.023 13.7 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein IceA2 PF05862.6 KND95154.1 - 0.27 10.9 0.2 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Methyltransf_11 PF08241.7 KND95155.1 - 3.9e-12 46.4 0.0 1.4e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND95155.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND95155.1 - 1.2e-06 29.0 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND95155.1 - 2.3e-06 27.6 0.0 7.4e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND95155.1 - 2.1e-05 23.7 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KND95155.1 - 2.8e-05 23.7 0.0 5.5e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND95155.1 - 5.4e-05 23.5 0.0 0.00017 21.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND95155.1 - 0.00054 19.3 0.0 0.0021 17.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KND95155.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 KND95155.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF2178 PF09946.4 KND95156.1 - 0.076 12.7 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Cys_Met_Meta_PP PF01053.15 KND95158.1 - 1.1e-58 198.4 0.0 2.7e-58 197.1 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KND95158.1 - 0.17 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Polysacc_deac_1 PF01522.16 KND95159.1 - 1.7e-20 72.8 0.0 2.4e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 KND95159.1 - 0.029 13.3 0.0 0.076 12.0 0.0 1.7 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase HTH_39 PF14090.1 KND95159.1 - 0.055 12.9 0.2 0.89 9.0 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.27 KND95162.1 - 7.5e-25 85.8 10.6 3.8e-06 26.5 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KND95162.1 - 0.00093 17.4 2.0 0.0021 16.2 0.6 2.2 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF4149 PF13664.1 KND95163.1 - 9.7e-16 57.6 0.3 6.3e-15 55.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku_N PF03731.10 KND95164.1 - 3.5e-23 82.2 0.1 5.9e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KND95164.1 - 6.7e-23 81.1 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 KND95164.1 - 2.2e-14 53.4 0.0 6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like DUF1295 PF06966.7 KND95165.1 - 1e-36 126.4 6.4 1.3e-36 126.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KND95165.1 - 0.0027 17.8 1.1 0.12 12.6 0.0 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Hydrolase_6 PF13344.1 KND95166.1 - 1.1e-26 92.6 0.0 1.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND95166.1 - 2.2e-12 47.8 0.0 4.4e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND95166.1 - 2e-11 43.4 0.0 6.5e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like DUF3893 PF13032.1 KND95166.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) DUF3602 PF12223.3 KND95167.1 - 2.1e-10 40.8 18.9 0.00053 20.3 1.8 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-BED PF02892.10 KND95168.1 - 0.0096 15.6 2.4 0.019 14.7 1.7 1.5 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 KND95168.1 - 0.011 16.0 3.1 0.037 14.3 2.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND95168.1 - 0.022 15.0 2.6 0.067 13.5 1.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1183 PF06682.7 KND95168.1 - 0.13 11.8 3.4 0.23 11.0 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) zf-H2C2_2 PF13465.1 KND95168.1 - 0.32 11.3 2.5 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DnaJ PF00226.26 KND95169.1 - 7.6e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KND95169.1 - 0.00019 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.1 KND95169.1 - 0.16 11.3 3.5 0.26 10.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Abhydrolase_4 PF08386.5 KND95170.1 - 2.1e-18 66.0 0.9 2.2e-17 62.8 0.0 2.7 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_1 PF00561.15 KND95170.1 - 2.4e-18 66.5 0.0 1.9e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND95170.1 - 6.2e-07 29.5 2.0 4e-06 26.8 0.3 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND95170.1 - 0.073 12.8 0.1 3.6 7.3 0.1 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family NUDIX PF00293.23 KND95171.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 NUDIX domain Stb3 PF10330.4 KND95172.1 - 4.7e-36 122.3 0.0 8.3e-36 121.5 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 KND95173.1 - 4.3e-90 302.4 0.0 4.8e-86 289.1 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KND95173.1 - 2.7e-19 69.0 0.0 5.7e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Toprim domain TGS PF02824.16 KND95175.1 - 7.2e-22 76.9 0.2 1.4e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KND95175.1 - 8.1e-17 61.2 0.0 1.9e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND95175.1 - 2.5e-09 36.6 0.0 1.2e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KND95175.1 - 2.7e-05 23.6 0.1 0.44 9.9 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KND95175.1 - 0.0002 21.2 0.0 0.044 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KND95175.1 - 0.024 13.4 0.1 0.053 12.2 0.1 1.5 1 0 0 1 1 1 0 ArgK protein HTH_Tnp_Tc5 PF03221.11 KND95176.1 - 1.9e-11 43.5 0.3 6.1e-10 38.7 0.1 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KND95176.1 - 6.5e-09 35.0 0.1 1.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KND95176.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.2 KND95176.1 - 0.016 14.8 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 MarR family MarR PF01047.17 KND95176.1 - 0.018 14.7 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 KND95176.1 - 0.034 13.8 0.3 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 KND95176.1 - 0.039 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.11 KND95176.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Herpes_LAMP2 PF06126.6 KND95176.1 - 0.52 8.6 3.8 0.75 8.1 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Tubulin PF00091.20 KND95177.1 - 1.8e-64 217.5 0.0 2.3e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KND95177.1 - 2.5e-41 140.6 0.0 4e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KND95177.1 - 7.8e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 KND95177.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Ank_2 PF12796.2 KND95179.1 - 6.4e-25 87.3 0.0 3.6e-17 62.4 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KND95179.1 - 1.3e-18 65.7 8.8 5.3e-08 32.2 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KND95179.1 - 1.7e-15 56.6 8.2 2.1e-07 30.9 0.1 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND95179.1 - 5.4e-15 55.4 0.2 2.2e-08 34.3 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND95179.1 - 4.7e-14 51.0 0.0 2.5e-05 24.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat RCR PF12273.3 KND95180.1 - 0.029 14.9 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1049 PF06305.6 KND95180.1 - 0.25 10.8 0.1 0.25 10.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) CcmD PF04995.9 KND95180.1 - 6.8 6.5 5.8 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) WSC PF01822.14 KND95181.1 - 3.7e-34 116.4 27.7 9.5e-19 67.1 6.2 5.7 5 2 0 6 6 6 2 WSC domain DUF2413 PF10310.4 KND95181.1 - 0.51 9.0 9.3 0.81 8.4 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ribosomal_S19 PF00203.16 KND95182.1 - 2.1e-33 113.7 0.3 3.7e-33 112.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 DUF462 PF04315.7 KND95182.1 - 0.11 11.8 0.0 7.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF462 Steroid_dh PF02544.11 KND95183.1 - 8.2e-13 48.3 2.3 8.2e-13 48.3 1.6 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KND95183.1 - 0.066 13.3 1.7 0.18 11.9 0.1 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase Nefa_Nip30_N PF10187.4 KND95184.1 - 0.013 15.6 1.0 0.018 15.1 0.7 1.2 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 ubiquitin PF00240.18 KND95185.1 - 1.9e-06 27.1 0.0 2.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family zf-HC5HC2H_2 PF13832.1 KND95186.1 - 5.8e-34 116.4 8.6 5.8e-34 116.4 6.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KND95186.1 - 3.7e-26 91.0 8.2 3.7e-26 91.0 5.7 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KND95186.1 - 4.9e-21 75.6 1.3 3e-20 73.0 0.2 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 KND95186.1 - 9.6e-15 53.6 2.4 9.6e-15 53.6 1.7 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KND95186.1 - 8.4e-08 31.7 28.2 5.3e-07 29.2 8.9 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 KND95186.1 - 7.5 6.6 26.9 0.094 12.7 5.6 3.1 2 1 1 3 3 3 0 RING-like domain HLH PF00010.21 KND95187.1 - 8.6e-12 44.5 0.7 2.7e-11 42.9 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DAO PF01266.19 KND95189.1 - 5.9e-36 124.1 0.0 7.6e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND95189.1 - 0.0008 19.3 0.0 0.011 15.5 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND95189.1 - 0.0031 17.4 0.0 0.009 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KND95189.1 - 0.0047 16.7 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 ThiF family GIDA PF01134.17 KND95189.1 - 0.02 13.7 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KND95189.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KND95189.1 - 0.089 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KND95189.1 - 0.11 12.6 0.0 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TMEM154 PF15102.1 KND95190.1 - 0.00015 21.5 1.2 0.00035 20.3 0.8 1.6 1 0 0 1 1 1 1 TMEM154 protein family Nitrate_red_gam PF02665.9 KND95190.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PhyH PF05721.8 KND95191.1 - 1.3e-07 31.8 0.1 6.9e-06 26.2 0.1 2.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.14 KND95191.1 - 0.049 13.3 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 AraC-like ligand binding domain DEAD PF00270.24 KND95192.1 - 4.5e-29 101.1 0.0 9.1e-29 100.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND95192.1 - 1e-16 60.5 0.0 2.7e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KND95192.1 - 2.8e-05 23.0 0.0 4.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KND95192.1 - 0.00036 20.4 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KND95192.1 - 0.034 12.5 0.1 0.2 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DPCD PF14913.1 KND95192.1 - 0.049 12.7 0.1 0.099 11.7 0.1 1.4 1 0 0 1 1 1 0 DPCD protein family Herpes_UL6 PF01763.11 KND95192.1 - 0.33 9.0 0.0 0.5 8.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like AlcCBM31 PF11606.3 KND95193.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein Peptidase_M76 PF09768.4 KND95195.1 - 5.8e-69 230.9 1.1 7.3e-69 230.6 0.8 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KND95195.1 - 0.0034 17.0 3.4 0.0034 17.0 2.4 1.9 1 1 1 2 2 2 1 SprT-like family Cys_knot PF00007.17 KND95195.1 - 0.04 14.0 1.5 0.85 9.7 0.3 2.2 2 0 0 2 2 2 0 Cystine-knot domain Peptidase_MA_2 PF13485.1 KND95195.1 - 0.11 12.5 1.0 0.2 11.7 0.7 1.5 1 1 0 1 1 1 0 Peptidase MA superfamily UPF0113 PF03657.8 KND95196.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KND95196.1 - 0.043 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 PUA domain TIP41 PF04176.8 KND95197.1 - 6.4e-74 247.1 1.6 8e-74 246.8 1.1 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 KND95198.1 - 6.7e-70 235.2 0.0 8.5e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95198.1 - 7.1e-43 146.5 0.0 9.2e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND95198.1 - 5.5e-06 25.5 0.0 1.2e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND95198.1 - 0.00043 19.4 0.0 0.00069 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAM220 PF15487.1 KND95198.1 - 0.002 17.5 0.8 0.0029 17.0 0.6 1.2 1 0 0 1 1 1 1 FAM220 family RIO1 PF01163.17 KND95198.1 - 0.0095 15.3 0.0 0.035 13.4 0.0 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 KND95198.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND95198.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DEAD PF00270.24 KND95200.1 - 1.3e-20 73.6 0.0 4.8e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND95200.1 - 4.5e-20 71.2 0.1 1e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND95200.1 - 9.7e-20 71.1 0.0 2.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND95200.1 - 0.00064 19.8 0.0 0.015 15.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain ArfGap PF01412.13 KND95202.1 - 2.5e-33 114.3 0.0 2.5e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KND95202.1 - 2.5e-12 46.9 0.1 7.6e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 PH domain Membr_traf_MHD PF10540.4 KND95203.1 - 1.4e-18 67.0 0.1 3.1e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KND95203.1 - 1.2e-16 60.2 0.0 2.8e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KND95203.1 - 2.7e-08 32.5 0.1 4.2e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF810) K_channel_TID PF07941.6 KND95203.1 - 1 9.6 4.5 0.35 11.1 0.5 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-H2C2_2 PF13465.1 KND95204.1 - 2.3e-10 40.2 13.0 1.2e-05 25.3 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KND95204.1 - 8.6e-10 38.3 15.5 1.9e-05 24.7 3.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND95204.1 - 3e-06 27.1 13.7 0.00019 21.5 1.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KND95204.1 - 1.9e-05 24.6 1.5 1.9e-05 24.6 1.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND95204.1 - 0.00011 22.1 2.1 0.00011 22.1 1.4 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND95204.1 - 0.0038 17.0 1.5 0.0038 17.0 1.1 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KND95204.1 - 0.041 13.9 1.1 0.041 13.9 0.8 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KND95204.1 - 2.4 8.0 5.9 0.93 9.3 1.1 2.1 1 1 1 2 2 2 0 BED zinc finger SF3b1 PF08920.5 KND95205.1 - 1.8e-24 86.4 3.6 1e-23 83.9 0.1 2.6 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KND95205.1 - 9.2e-14 51.4 4.3 0.0078 16.4 0.0 7.4 5 3 4 9 9 9 6 HEAT repeats HEAT PF02985.17 KND95205.1 - 2e-11 42.9 7.1 0.12 12.4 0.1 9.3 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KND95205.1 - 3.3e-10 40.1 0.7 0.44 11.0 0.0 8.0 8 1 1 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KND95205.1 - 0.0001 22.6 0.1 0.9 9.9 0.0 5.1 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KND95205.1 - 0.013 14.8 0.1 1.1 8.5 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal Na_Ca_ex PF01699.19 KND95206.1 - 5.7e-49 165.3 27.2 6.6e-25 87.3 7.0 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PMM PF03332.8 KND95207.1 - 1.4e-102 341.9 0.0 1.7e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KND95207.1 - 0.0025 17.4 0.0 0.026 14.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 KND95207.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase NeA_P2 PF12312.3 KND95207.1 - 5.2 6.2 6.7 10 5.2 3.9 1.8 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein NDUFA12 PF05071.11 KND95208.1 - 1.4e-09 38.3 0.4 1.4e-09 38.3 0.3 1.9 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 KND95209.1 - 1.3e-10 41.2 0.0 2.8e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.6 KND95209.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin zf-B_box PF00643.19 KND95211.1 - 0.27 11.1 6.3 0.52 10.2 4.4 1.4 1 0 0 1 1 1 0 B-box zinc finger MFS_1 PF07690.11 KND95212.1 - 8.8e-36 123.3 42.4 8.8e-36 123.3 29.4 2.9 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND95212.1 - 7.1e-12 44.6 6.7 7.1e-12 44.6 4.7 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter RabGAP-TBC PF00566.13 KND95213.1 - 4.4e-27 94.9 0.0 8.1e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol_phi PF04931.8 KND95216.1 - 1.7e-49 168.4 30.1 2e-34 118.5 19.8 2.8 2 1 0 2 2 2 2 DNA polymerase phi SDA1 PF05285.7 KND95216.1 - 0.00036 19.9 14.1 0.00069 18.9 9.8 1.5 1 0 0 1 1 1 1 SDA1 EB1 PF03271.12 KND95216.1 - 0.05 13.6 0.0 0.23 11.5 0.0 2.1 1 0 0 1 1 1 0 EB1-like C-terminal motif Proteasome PF00227.21 KND95217.1 - 1.4e-44 151.6 0.0 4.7e-30 104.3 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KND95217.1 - 3.9e-10 38.8 0.6 5.9e-10 38.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2457 PF10446.4 KND95217.1 - 1.4 7.5 10.7 2 7.0 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CAP PF00188.21 KND95218.1 - 1.1e-19 71.1 3.3 1.4e-19 70.7 2.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-DNL PF05180.7 KND95219.1 - 5.6e-26 90.0 0.4 7.3e-26 89.6 0.3 1.1 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KND95219.1 - 0.0022 17.4 0.2 0.0037 16.7 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-C3HC4_3 PF13920.1 KND95219.1 - 0.17 11.5 1.9 0.3 10.8 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND95219.1 - 0.34 10.7 2.7 0.61 9.9 1.8 1.4 1 0 0 1 1 1 0 Ring finger domain TFIIS_C PF01096.13 KND95219.1 - 0.36 10.4 1.6 21 4.8 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KND95219.1 - 5 7.0 6.8 43 4.0 4.6 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Fungal_trans PF04082.13 KND95220.1 - 5.3e-21 74.6 0.6 7.8e-21 74.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95220.1 - 2.6e-07 30.4 9.1 4.1e-07 29.8 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF5 PF04855.7 KND95221.1 - 1.5e-84 283.3 0.0 2.1e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KND95221.1 - 0.0012 18.1 1.1 0.0029 16.9 0.7 1.7 1 0 0 1 1 1 1 GATA zinc finger Rhodanese PF00581.15 KND95222.1 - 1.2e-11 44.9 0.0 2.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain SOG2 PF10428.4 KND95223.1 - 8.3e-14 51.0 0.5 1e-13 50.7 0.0 1.4 2 0 0 2 2 2 1 RAM signalling pathway protein Arfaptin PF06456.8 KND95223.1 - 0.092 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain DRIM PF07539.7 KND95224.1 - 9e-42 141.8 0.1 4.6e-41 139.5 0.0 2.4 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_2 PF13646.1 KND95224.1 - 3.4e-09 36.8 4.1 0.2 11.9 0.0 7.6 7 2 1 8 8 8 4 HEAT repeats HEAT PF02985.17 KND95224.1 - 7.5e-09 34.9 3.8 0.52 10.5 0.0 8.8 7 0 0 7 7 7 2 HEAT repeat CwfJ_C_1 PF04677.10 KND95225.1 - 2.3e-24 85.3 0.0 1.1e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KND95225.1 - 4.3e-22 78.4 0.7 7.3e-22 77.6 0.5 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 GRASP55_65 PF04495.9 KND95226.1 - 1.8e-45 154.3 0.0 8.2e-45 152.1 0.0 1.9 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DAD PF02109.11 KND95227.1 - 1.1e-49 167.1 3.0 1.5e-49 166.7 2.0 1.1 1 0 0 1 1 1 1 DAD family DUF4534 PF15049.1 KND95227.1 - 0.084 12.5 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) HAD_2 PF13419.1 KND95228.1 - 1.8e-15 57.5 0.0 2.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND95228.1 - 1.3e-08 34.4 0.1 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KND95228.1 - 1.7e-08 35.1 0.0 2.5e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND95228.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 KND95228.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Peptidase_C15 PF01470.12 KND95229.1 - 1.1e-13 51.5 0.0 4.6e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Pyroglutamyl peptidase SDH_beta PF03315.10 KND95229.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Serine dehydratase beta chain DUF4110 PF13422.1 KND95230.1 - 1.9e-27 94.9 0.5 1.9e-27 94.9 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KND95230.1 - 3e-27 94.1 16.0 2.9e-09 36.8 0.2 6.9 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KND95230.1 - 2.7e-25 87.8 16.9 6.5e-07 29.0 0.0 7.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KND95230.1 - 2.2e-19 69.0 2.5 4.4e-06 26.5 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KND95230.1 - 6.1e-14 51.5 4.9 0.002 18.2 0.2 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KND95230.1 - 9.9e-13 47.3 3.6 0.00011 21.8 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KND95230.1 - 2.1e-11 43.1 2.7 4.7e-05 22.8 0.1 5.4 6 0 0 6 6 6 3 Kelch motif SGT1 PF07093.6 KND95230.1 - 2.6 6.2 18.7 7.6 4.7 11.7 1.9 2 0 0 2 2 2 0 SGT1 protein Daxx PF03344.10 KND95230.1 - 8.7 4.6 25.4 0.044 12.2 10.4 2.0 2 0 0 2 2 2 0 Daxx Family Methyltransf_15 PF09445.5 KND95231.1 - 1.4e-43 148.2 0.0 1.9e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KND95231.1 - 8.8e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND95231.1 - 0.0006 20.3 0.0 0.00092 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KND95231.1 - 0.0041 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 KND95231.1 - 0.0051 16.4 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 KND95231.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.6 KND95231.1 - 0.029 13.0 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_5 PF01795.14 KND95231.1 - 0.032 13.4 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_31 PF13847.1 KND95231.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FF PF01846.14 KND95232.1 - 4.5e-40 135.3 5.3 1.4e-11 44.1 0.7 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.21 KND95232.1 - 2.5e-16 59.2 16.2 2.6e-10 39.9 3.4 2.9 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 KND95233.1 - 1.2e-72 244.7 0.0 1.7e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.5 KND95234.1 - 3.1e-107 359.2 2.5 3.1e-107 359.2 1.7 1.8 2 0 0 2 2 2 1 DNA replication regulator SLD3 Homeobox PF00046.24 KND95235.1 - 6.9e-16 57.6 2.4 1.7e-15 56.3 1.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KND95235.1 - 0.011 15.4 1.0 0.026 14.2 0.7 1.6 1 0 0 1 1 1 0 Homeobox KN domain Rdx PF10262.4 KND95236.1 - 5.4e-28 96.8 0.0 7.9e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 KND95237.1 - 3.9e-26 90.5 0.0 4.8e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain PGAP1 PF07819.8 KND95237.1 - 0.068 12.7 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Cupin_8 PF13621.1 KND95238.1 - 3.8e-19 69.1 0.0 7.5e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KND95238.1 - 6.9e-10 39.1 0.1 1.7e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KND95238.1 - 5.5e-07 29.2 0.9 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KND95238.1 - 1.7e-05 24.2 0.0 3.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.7 KND95238.1 - 0.047 12.9 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 KND95238.1 - 0.068 12.6 0.1 0.61 9.6 0.0 2.4 3 0 0 3 3 3 0 Cupin domain DEAD PF00270.24 KND95239.1 - 2.9e-44 150.5 1.4 4.9e-44 149.7 0.8 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND95239.1 - 7.4e-28 96.2 0.2 4.7e-27 93.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND95239.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KND95239.1 - 0.0059 16.2 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND95239.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KND95239.1 - 0.04 14.0 0.1 0.16 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 KND95239.1 - 0.07 12.1 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 KND95239.1 - 0.075 12.7 0.1 0.29 10.8 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KND95239.1 - 0.091 11.8 0.0 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.9 KND95239.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein IATP PF04568.7 KND95240.1 - 2.8e-21 75.4 0.9 3.3e-21 75.1 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF1352 PF07086.7 KND95240.1 - 0.064 12.8 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) IncA PF04156.9 KND95240.1 - 0.16 11.5 2.7 0.2 11.2 1.9 1.1 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 KND95240.1 - 0.28 11.2 6.1 0.33 10.9 4.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1003 PF06210.6 KND95240.1 - 0.5 10.3 2.0 0.72 9.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) 14-3-3 PF00244.15 KND95242.1 - 2.2e-110 367.3 6.8 1.3e-96 322.2 1.1 2.0 2 0 0 2 2 2 2 14-3-3 protein zf-CSL PF05207.8 KND95243.1 - 7.6e-14 50.9 0.1 1.1e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KND95243.1 - 9e-13 47.7 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Ninjurin PF04923.7 KND95244.1 - 0.094 12.4 0.0 0.094 12.4 0.0 2.1 2 1 1 3 3 3 0 Ninjurin DUF202 PF02656.10 KND95244.1 - 0.098 12.8 2.7 1.7 8.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3329 PF11808.3 KND95244.1 - 0.12 12.5 1.0 0.43 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF2207 PF09972.4 KND95244.1 - 2.9 6.3 4.5 2.8 6.4 0.5 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 KND95244.1 - 3.3 7.3 7.3 14 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TMEM190 PF15431.1 KND95244.1 - 4.4 7.2 5.6 8.5 6.3 0.5 2.9 1 1 2 3 3 3 0 Transmembrane protein 190 GTP_EFTU PF00009.22 KND95245.1 - 1.8e-37 128.6 0.0 3.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KND95245.1 - 4.5e-36 122.7 0.3 9.6e-36 121.7 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KND95245.1 - 8.9e-10 38.5 0.2 1.9e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND95245.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KND95245.1 - 0.073 12.8 0.0 0.41 10.4 0.0 2.2 2 1 1 3 3 3 0 Dynamin family Nsp1_C PF05064.8 KND95247.1 - 1.5e-37 127.7 2.6 1.5e-37 127.7 1.8 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KND95247.1 - 1e-12 48.2 219.5 8.2e-08 32.4 30.9 6.7 2 1 5 7 7 7 5 Nucleoporin FG repeat region DUF948 PF06103.6 KND95247.1 - 0.031 14.1 0.3 0.086 12.7 0.1 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMCO5 PF14992.1 KND95247.1 - 0.28 10.2 4.9 0.39 9.8 3.4 1.1 1 0 0 1 1 1 0 TMCO5 family V-SNARE PF05008.10 KND95247.1 - 2.4 8.3 10.4 0.92 9.7 0.5 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus APG6 PF04111.7 KND95247.1 - 2.7 6.9 7.4 4.9 6.0 5.0 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Complex1_49kDa PF00346.14 KND95249.1 - 1.1e-133 444.3 0.0 1.4e-133 444.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KND95249.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase FAD_binding_3 PF01494.14 KND95250.1 - 4.4e-23 81.9 0.0 1.5e-21 76.9 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND95250.1 - 5.3e-06 25.5 0.3 0.051 12.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KND95250.1 - 0.00028 19.9 0.7 0.0033 16.4 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein K_oxygenase PF13434.1 KND95250.1 - 0.014 14.3 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) SE PF08491.5 KND95250.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.1 KND95250.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND95250.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND95250.1 - 0.024 13.3 0.0 0.5 8.9 0.0 2.4 2 1 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KND95250.1 - 0.036 14.0 0.2 0.09 12.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ELMO_CED12 PF04727.8 KND95251.1 - 1.4e-47 161.4 0.0 3.2e-47 160.2 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 KND95251.1 - 5.6e-06 26.1 0.2 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) VIT1 PF01988.14 KND95252.1 - 6.3e-36 123.8 4.2 2.6e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 VIT family DUF1768 PF08719.6 KND95253.1 - 2.2e-13 50.2 0.0 2.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ketoacyl-synt PF00109.21 KND95254.1 - 2.4e-77 259.8 0.0 5.8e-77 258.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KND95254.1 - 2.3e-46 158.5 0.4 1.3e-45 156.0 0.0 2.4 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KND95254.1 - 2.2e-29 101.7 0.5 6.6e-29 100.1 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KND95254.1 - 1.6e-24 86.1 0.0 2.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KND95254.1 - 4.2e-22 78.1 8.6 2.8e-11 43.4 0.8 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site adh_short PF00106.20 KND95254.1 - 8e-06 25.8 0.0 7.9e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.18 KND95254.1 - 8.3e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 KND95254.1 - 0.00018 21.0 0.0 0.0004 19.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_5 PF12695.2 KND95254.1 - 0.00033 20.4 2.9 0.031 14.0 0.0 3.9 4 0 0 4 4 4 1 Alpha/beta hydrolase family KR PF08659.5 KND95254.1 - 0.00085 19.0 0.0 0.0027 17.3 0.0 1.8 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND95254.1 - 0.014 14.3 0.0 0.075 11.9 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KND95254.1 - 0.029 13.2 0.0 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KND95254.1 - 0.17 10.5 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_2 PF00891.13 KND95255.1 - 2.4e-41 141.5 0.0 3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KND95255.1 - 0.0069 16.9 0.0 0.018 15.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND95255.1 - 0.012 16.0 0.0 0.048 14.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain WD40_alt PF14077.1 KND95255.1 - 0.023 14.2 0.1 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif ATP-grasp_2 PF08442.5 KND95256.1 - 7.4e-46 156.0 0.0 1.4e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ribul_P_3_epim PF00834.14 KND95256.1 - 2.6e-45 154.0 0.0 9.6e-44 148.8 0.0 2.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Ligase_CoA PF00549.14 KND95256.1 - 3.9e-15 55.7 0.7 9.1e-15 54.5 0.5 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KND95256.1 - 2e-08 33.7 0.0 4.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain OMPdecase PF00215.19 KND95256.1 - 0.042 13.2 0.1 0.14 11.5 0.1 1.8 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family CFEM PF05730.6 KND95257.1 - 5.2e-14 51.8 12.8 9.2e-14 51.0 8.9 1.4 1 0 0 1 1 1 1 CFEM domain Mucin PF01456.12 KND95257.1 - 0.076 12.7 14.7 0.12 12.1 10.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 KND95257.1 - 1 7.1 11.0 1.2 6.9 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraT PF05818.7 KND95257.1 - 3.7 6.8 11.9 1.5 8.1 6.7 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 KND95257.1 - 4.2 7.0 21.2 0.18 11.4 10.9 1.6 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain RAP1 PF07218.6 KND95257.1 - 4.9 5.1 12.1 5.9 4.8 8.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_6 PF12697.2 KND95258.1 - 2.1e-19 70.3 0.1 3.3e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND95258.1 - 1.8e-09 37.4 0.2 3.1e-09 36.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND95258.1 - 0.00065 19.3 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 KND95258.1 - 0.0071 15.9 0.2 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KND95258.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 KND95258.1 - 0.028 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PAF-AH_p_II PF03403.8 KND95258.1 - 0.08 11.2 0.1 3.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.9 KND95258.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Zn_clus PF00172.13 KND95259.1 - 3.1e-08 33.3 8.3 5.6e-08 32.5 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.10 KND95260.1 - 6.4e-41 138.7 0.2 6.4e-41 138.7 0.1 2.7 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND95260.1 - 2.4e-32 111.3 0.2 2.4e-32 111.3 0.2 4.4 3 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 KND95260.1 - 2.2e-30 105.6 0.0 1.7e-29 102.7 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase CW_binding_1 PF01473.15 KND95261.1 - 0.024 14.7 0.4 0.042 13.9 0.3 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat Fungal_trans PF04082.13 KND95262.1 - 1.5e-24 86.3 0.1 3e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95262.1 - 1.2e-07 31.5 14.2 2.9e-07 30.2 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2642 PF10842.3 KND95262.1 - 0.11 11.9 0.1 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Dus PF01207.12 KND95263.1 - 1.8e-57 194.5 0.0 2.6e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) adh_short PF00106.20 KND95264.1 - 0.066 13.1 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase SseC PF04888.7 KND95264.1 - 0.14 11.5 0.3 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DHFR_1 PF00186.14 KND95266.1 - 8.4e-23 80.7 0.0 1.7e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase DSBA PF01323.15 KND95266.1 - 0.027 14.0 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Ubiq_cyt_C_chap PF03981.7 KND95267.1 - 1.4e-33 115.6 0.1 2.2e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Sugar_tr PF00083.19 KND95268.1 - 2.2e-62 211.0 27.7 2.6e-62 210.9 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND95268.1 - 1.9e-20 72.8 49.1 5.9e-16 58.1 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_trans PF01144.18 KND95269.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase CoA_trans PF01144.18 KND95270.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Fungal_trans_2 PF11951.3 KND95271.1 - 2.9e-09 36.0 0.4 5e-09 35.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95271.1 - 3.6e-08 33.1 9.1 7.1e-08 32.2 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KND95273.1 - 4.3e-51 172.5 0.0 1.8e-42 144.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND95273.1 - 2.4e-07 30.9 0.0 6.3e-05 23.0 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KND95273.1 - 3.6e-06 26.4 0.0 3.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KND95273.1 - 2.3e-05 24.3 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KND95273.1 - 5.9e-05 23.2 0.0 0.0031 17.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KND95273.1 - 0.00069 19.5 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND95273.1 - 0.00099 18.8 0.0 0.005 16.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KND95273.1 - 0.0017 18.2 2.7 0.0096 15.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 KND95273.1 - 0.0063 15.2 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 KND95273.1 - 0.0069 16.5 0.0 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KND95273.1 - 0.011 16.0 1.5 0.047 14.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KND95273.1 - 0.015 16.0 4.1 0.024 15.4 0.0 3.4 4 0 0 4 4 2 0 AAA domain RuvB_N PF05496.7 KND95273.1 - 0.018 14.1 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KND95273.1 - 0.019 14.9 0.0 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KND95273.1 - 0.024 14.3 3.3 0.029 14.1 0.1 2.7 3 0 0 3 3 2 0 Part of AAA domain Mg_chelatase PF01078.16 KND95273.1 - 0.05 12.7 0.1 0.13 11.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KND95273.1 - 0.057 13.0 0.1 0.19 11.3 0.1 2.0 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 KND95273.1 - 0.072 11.9 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KND95273.1 - 0.091 12.2 0.0 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Torsin PF06309.6 KND95273.1 - 0.53 10.1 0.4 1.4 8.8 0.0 1.8 2 0 0 2 2 2 0 Torsin RNase_T PF00929.19 KND95276.1 - 2.8e-23 82.9 0.0 5.4e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease PGM_PMM_III PF02880.11 KND95276.1 - 4e-23 81.5 0.0 7.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 KND95276.1 - 3.8e-19 68.5 0.0 3.7e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KND95276.1 - 1.4e-15 57.4 0.1 2.8e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KND95276.1 - 2.5e-08 33.8 0.0 5.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 KND95277.1 - 4.5e-11 43.3 0.0 1.2e-10 41.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KND95277.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F-box-like PF12937.2 KND95278.1 - 0.0064 16.2 0.8 0.0064 16.2 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KND95278.1 - 0.12 12.0 4.5 7.3 6.3 0.1 3.2 3 0 0 3 3 3 0 F-box domain ATG11 PF10377.4 KND95279.1 - 9.3e-37 125.8 1.0 4.2e-36 123.7 0.1 2.8 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 KND95279.1 - 0.0014 17.4 3.7 0.0014 17.4 2.5 5.1 4 2 0 5 5 5 1 Autophagy protein Apg17 DUF869 PF05911.6 KND95279.1 - 2.2 6.3 60.8 0.86 7.7 0.7 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Tropomyosin_1 PF12718.2 KND95279.1 - 7.4 6.4 81.1 0.02 14.7 17.1 6.8 4 1 1 5 5 5 0 Tropomyosin like CENP-H PF05837.7 KND95281.1 - 7.8e-23 80.6 1.7 1.5e-21 76.5 0.1 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DivIC PF04977.10 KND95281.1 - 0.0089 15.4 5.2 0.72 9.3 0.7 2.9 2 1 1 3 3 3 2 Septum formation initiator AATF-Che1 PF13339.1 KND95281.1 - 0.16 12.1 2.1 9.7 6.3 0.3 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Biotin_lipoyl PF00364.17 KND95282.1 - 2e-21 75.4 1.1 3.7e-21 74.5 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KND95282.1 - 1.7e-07 30.7 0.4 4.5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KND95282.1 - 6.1e-05 22.5 1.3 0.0009 18.8 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.2 KND95282.1 - 0.0038 16.4 1.1 1 8.4 0.5 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 KND95282.1 - 0.0093 16.2 1.3 0.3 11.4 0.0 2.6 1 1 1 2 2 2 1 HlyD family secretion protein HMG_box PF00505.14 KND95283.1 - 9.4e-25 86.6 1.1 1.5e-24 86.0 0.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KND95283.1 - 5.6e-19 68.2 1.9 1.1e-18 67.3 1.1 1.6 1 1 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KND95283.1 - 0.00089 18.9 0.7 0.0018 18.0 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 EF-hand_4 PF12763.2 KND95284.1 - 1e-25 89.4 0.0 2e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KND95284.1 - 1.9e-05 24.5 25.4 1.9e-05 24.5 17.6 7.3 5 2 2 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 KND95284.1 - 0.0011 19.0 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KND95284.1 - 0.005 16.6 0.2 0.96 9.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain tRNA-synt_1d PF00750.14 KND95285.1 - 9.6e-47 159.4 3.5 1.7e-34 119.2 1.5 3.2 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KND95285.1 - 2.4e-24 85.6 0.3 1e-23 83.5 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain LRR_4 PF12799.2 KND95286.1 - 1.4e-15 56.5 3.9 0.00015 21.2 2.0 4.8 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND95286.1 - 1e-10 41.2 5.1 2.3e-07 30.4 0.7 3.3 2 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KND95286.1 - 7e-08 31.4 7.1 2 8.7 0.2 6.8 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 KND95286.1 - 0.0014 18.5 2.7 1.2e+02 3.2 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 KND95286.1 - 0.017 15.2 7.8 80 4.1 0.1 6.5 7 0 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 KND95287.1 - 0.032 13.8 2.1 4 7.1 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) AsiA PF09010.5 KND95287.1 - 0.25 11.2 0.2 3.9 7.4 0.0 2.6 3 0 0 3 3 3 0 Anti-Sigma Factor A Peroxin-3 PF04882.7 KND95289.1 - 2.4e-141 471.3 0.0 2.7e-141 471.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 RPE65 PF03055.10 KND95291.1 - 4.4e-115 385.0 0.0 5e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fork_head PF00250.13 KND95292.1 - 7e-34 115.7 0.1 1.2e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Fork head domain Fungal_trans PF04082.13 KND95293.1 - 4.4e-27 94.6 1.1 4.4e-27 94.6 0.7 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain UCH PF00443.24 KND95294.1 - 1.1e-41 142.7 0.0 1.8e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KND95294.1 - 1.6e-22 79.3 3.7 4.2e-20 71.6 1.0 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KND95294.1 - 5.7e-22 76.9 0.2 6e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KND95294.1 - 1.7e-16 60.5 0.0 1.3e-13 51.1 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ABC_tran PF00005.22 KND95295.1 - 3e-32 111.7 0.0 4.2e-15 56.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND95295.1 - 3.5e-14 53.4 5.9 0.0014 18.6 0.0 4.3 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 KND95295.1 - 1.8e-12 46.5 4.5 1.8e-12 46.5 3.1 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 KND95295.1 - 8.7e-11 41.4 0.2 0.0012 18.0 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KND95295.1 - 1.7e-07 30.6 0.1 0.79 8.6 0.0 4.4 5 0 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 KND95295.1 - 2.8e-07 31.3 0.1 0.0089 16.8 0.0 2.8 2 2 0 2 2 2 2 AAA domain Fer4 PF00037.22 KND95295.1 - 8.7e-06 25.1 2.7 8.7e-06 25.1 1.9 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.24 KND95295.1 - 1e-05 25.7 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KND95295.1 - 1.4e-05 25.3 0.1 0.19 12.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KND95295.1 - 4e-05 23.0 0.1 0.068 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KND95295.1 - 4.3e-05 23.6 0.0 0.0072 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KND95295.1 - 0.00022 20.4 1.2 0.85 8.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4_21 PF14697.1 KND95295.1 - 0.00026 20.7 10.2 0.00049 19.9 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 KND95295.1 - 0.00031 20.8 0.0 0.18 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KND95295.1 - 0.00038 20.3 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KND95295.1 - 0.00048 19.7 0.1 0.0072 15.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KND95295.1 - 0.00066 20.0 0.1 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KND95295.1 - 0.00069 19.3 0.5 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KND95295.1 - 0.00081 19.0 0.3 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain VirE PF05272.6 KND95295.1 - 0.0013 18.2 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E SRP54 PF00448.17 KND95295.1 - 0.0017 17.8 1.8 0.084 12.2 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.2 KND95295.1 - 0.0021 18.4 6.9 0.006 16.9 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.1 KND95295.1 - 0.0021 18.0 0.0 0.56 10.1 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 KND95295.1 - 0.0038 16.6 0.0 2.9 7.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.10 KND95295.1 - 0.0041 15.8 0.0 0.092 11.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_6 PF12837.2 KND95295.1 - 0.0062 16.3 1.6 0.0062 16.3 1.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.9 KND95295.1 - 0.011 15.5 0.9 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 KND95295.1 - 0.011 14.2 0.0 0.011 14.2 0.0 2.1 4 0 0 4 4 3 0 AAA domain Thymidylate_kin PF02223.12 KND95295.1 - 0.016 14.5 0.6 3.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Fer4_10 PF13237.1 KND95295.1 - 0.027 14.2 1.7 0.027 14.2 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Miro PF08477.8 KND95295.1 - 0.031 14.7 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 KND95295.1 - 0.04 13.4 2.4 0.33 10.4 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KND95295.1 - 0.05 12.4 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KND95295.1 - 0.065 13.2 0.0 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KND95295.1 - 0.071 13.8 0.2 0.071 13.8 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_30 PF13604.1 KND95295.1 - 0.15 11.6 0.2 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 KND95295.1 - 0.2 11.7 9.0 0.58 10.2 6.2 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 KND95295.1 - 0.2 11.3 1.3 11 5.6 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 KND95295.1 - 0.23 11.3 1.5 14 5.6 0.0 3.3 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KND95295.1 - 0.24 10.9 0.8 3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KND95295.1 - 0.29 9.9 0.6 4.3 6.1 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Fer4_2 PF12797.2 KND95295.1 - 0.39 10.7 11.7 0.19 11.7 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 KND95295.1 - 1 9.6 13.5 0.052 13.8 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain FTA4 PF13093.1 KND95296.1 - 3.4e-53 180.2 0.0 4.4e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Seryl_tRNA_N PF02403.17 KND95296.1 - 0.066 13.2 1.2 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HORMA PF02301.13 KND95297.1 - 1.2e-31 109.8 0.0 1.5e-30 106.2 0.0 2.0 1 1 0 1 1 1 1 HORMA domain MIF4G PF02854.14 KND95299.1 - 1.3e-26 93.2 0.3 1.3e-26 93.2 0.2 1.9 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KND95299.1 - 7.7e-22 77.1 0.0 3.8e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 MA3 domain FAM176 PF14851.1 KND95299.1 - 0.26 10.9 4.9 0.7 9.5 3.4 1.7 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 KND95299.1 - 0.66 10.2 9.0 1.8 8.8 4.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAD_binding_3 PF01494.14 KND95301.1 - 8.5e-16 57.9 0.0 1.5e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND95301.1 - 1e-05 24.6 0.3 0.023 13.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND95301.1 - 8.2e-05 21.6 0.0 0.0002 20.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KND95301.1 - 0.00024 21.0 0.1 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KND95301.1 - 0.0017 18.3 0.1 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND95301.1 - 0.0026 16.7 0.9 0.015 14.2 0.2 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KND95301.1 - 0.007 15.4 0.3 0.25 10.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND95301.1 - 0.034 12.6 0.1 0.23 9.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ADH_N PF08240.7 KND95302.1 - 0.00048 19.8 0.5 0.00085 19.0 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND95302.1 - 0.0043 16.5 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3453 PF11935.3 KND95303.1 - 7.7e-67 225.1 0.0 1.2e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.4 KND95304.1 - 3.7e-05 23.6 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 RRM_1 PF00076.17 KND95305.1 - 1.5e-13 50.1 0.4 6.9e-10 38.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95305.1 - 2.9e-10 39.8 0.0 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95305.1 - 3.6e-09 36.4 0.0 4.3e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.9 KND95305.1 - 0.082 12.8 0.2 0.082 12.8 0.1 3.6 4 1 0 4 4 4 0 RNA polymerase III RPC4 Dicty_REP PF05086.7 KND95305.1 - 1.3 6.7 5.6 1.8 6.1 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.9 KND95305.1 - 3.3 5.6 14.3 5.2 4.9 9.9 1.3 1 0 0 1 1 1 0 CDC45-like protein adh_short_C2 PF13561.1 KND95306.1 - 1.7e-22 80.3 0.1 2.1e-22 80.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND95306.1 - 3.7e-12 46.4 1.4 4.5e-12 46.1 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND95306.1 - 1.8e-05 24.5 0.2 2.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 KND95306.1 - 0.048 13.9 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding MFMR PF07777.6 KND95306.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR THF_DHG_CYH_C PF02882.14 KND95306.1 - 0.073 12.1 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KND95306.1 - 0.097 12.0 0.1 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND95306.1 - 0.11 12.5 2.0 0.24 11.3 1.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KND95306.1 - 0.12 12.1 4.0 0.39 10.5 2.7 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DEAD PF00270.24 KND95308.1 - 3.1e-41 140.6 0.0 2.6e-40 137.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND95308.1 - 8.8e-28 95.9 0.2 9.4e-27 92.7 0.1 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KND95308.1 - 7.5e-05 21.6 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KND95308.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.1 KND95308.1 - 0.21 11.8 8.3 0.6 10.4 5.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 KND95308.1 - 1.3 8.7 4.9 2.3 8.0 3.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 KND95308.1 - 1.5 8.4 9.0 2.5 7.7 6.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 KND95308.1 - 1.7 8.1 7.0 2.8 7.5 4.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KND95308.1 - 5.8 6.4 7.8 11 5.5 5.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF413 PF04219.7 KND95309.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF SAD_SRA PF02182.12 KND95310.1 - 1.6e-05 24.2 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Pkinase PF00069.20 KND95311.1 - 5.5e-60 202.7 0.0 6.6e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95311.1 - 3.1e-35 121.5 0.0 4.1e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND95311.1 - 1.3e-07 30.8 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TruD PF01142.13 KND95312.1 - 5.7e-52 176.6 0.0 3.2e-49 167.5 0.0 3.2 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Ribosomal_S8 PF00410.14 KND95313.1 - 2.2e-25 88.9 0.0 3.1e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.7 KND95314.1 - 1.3e-18 66.9 8.1 1.1e-15 57.3 4.4 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 Rotamase_3 PF13616.1 KND95315.1 - 1.4e-17 64.0 0.1 2.2e-17 63.3 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KND95315.1 - 1.1e-15 58.0 0.1 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KND95315.1 - 2.3e-05 25.0 0.9 4.6e-05 24.0 0.7 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.21 KND95316.1 - 3.3e-28 97.0 1.6 4.2e-28 96.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mon1 PF03164.9 KND95317.1 - 1.3e-114 383.0 0.0 1.6e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF3432 PF11914.3 KND95317.1 - 0.16 12.0 4.7 0.33 10.9 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Dopey_N PF04118.9 KND95318.1 - 4.2e-116 387.0 0.0 1.4e-115 385.3 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal HEAT_EZ PF13513.1 KND95318.1 - 0.0071 16.7 5.2 23 5.6 0.1 5.1 4 0 0 4 4 4 2 HEAT-like repeat Fungal_trans PF04082.13 KND95319.1 - 1.9e-18 66.3 0.6 2.7e-18 65.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95319.1 - 1.2e-08 34.7 11.0 3.1e-08 33.3 7.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.9 KND95320.1 - 1.7e-136 454.7 2.8 2e-136 454.4 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_6 PF12697.2 KND95323.1 - 2.7e-19 69.9 0.1 3.3e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND95323.1 - 1.2e-13 51.1 0.0 7.1e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND95323.1 - 5.4e-08 32.7 0.1 1.6e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KND95323.1 - 7.1e-05 21.4 0.0 0.00026 19.5 0.0 1.9 1 1 0 1 1 1 1 Ndr family Glyco_hydro_18 PF00704.23 KND95324.1 - 6.9e-11 42.1 0.0 9.3e-09 35.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF1446 PF07287.6 KND95325.1 - 3.5e-29 101.4 0.2 5.3e-18 64.6 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF1446) ECH PF00378.15 KND95326.1 - 5.7e-42 143.5 0.0 8e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KND95326.1 - 0.0001 22.1 0.1 0.00088 19.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 DUF3005 PF11448.3 KND95326.1 - 0.047 13.2 0.1 9.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) Prefoldin_2 PF01920.15 KND95328.1 - 1.4e-18 66.5 10.6 5.4e-16 58.2 0.9 2.0 2 0 0 2 2 2 2 Prefoldin subunit Tho2 PF11262.3 KND95328.1 - 0.04 12.9 2.5 3.5 6.5 0.8 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HrpB7 PF09486.5 KND95328.1 - 0.052 13.4 0.9 3.2 7.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.6 KND95328.1 - 0.079 13.3 1.5 1.8 9.0 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Borrelia_lipo_1 PF05714.6 KND95328.1 - 0.13 11.3 3.1 0.63 9.0 0.5 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Taxilin PF09728.4 KND95328.1 - 0.16 11.0 4.6 3 6.8 0.4 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Spc24 PF08286.6 KND95328.1 - 0.29 10.8 3.4 1.3 8.6 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 KND95328.1 - 0.47 10.0 6.1 1.4 8.5 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF641 PF04859.7 KND95328.1 - 0.63 9.8 6.0 0.35 10.6 0.2 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 KND95328.1 - 1.6 8.6 7.0 0.6 10.0 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2205 PF10224.4 KND95328.1 - 2.3 7.8 5.2 5.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4337 PF14235.1 KND95328.1 - 3.1 7.6 6.7 1.2 8.9 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) IncA PF04156.9 KND95328.1 - 3.8 7.0 5.4 13 5.3 3.7 1.8 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KND95328.1 - 6.1 6.7 8.3 1.9 8.3 1.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PH PF00169.24 KND95329.1 - 4.5e-05 23.5 0.2 0.00022 21.3 0.0 2.3 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 KND95329.1 - 5e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sod_Fe_C PF02777.13 KND95330.1 - 2.8e-10 39.9 0.0 7.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KND95330.1 - 0.0062 16.7 0.0 0.0099 16.1 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3661 PF12400.3 KND95331.1 - 1.4e-41 141.5 3.3 2.1e-41 141.0 2.3 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein IBR PF01485.16 KND95331.1 - 1.6e-08 34.3 51.6 6.2e-06 25.9 6.0 4.2 4 0 0 4 4 4 3 IBR domain DUF4366 PF14283.1 KND95331.1 - 0.46 9.8 1.7 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) NAD_binding_1 PF00175.16 KND95332.1 - 6.5e-26 91.0 0.0 9.6e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KND95332.1 - 7.9e-26 90.0 0.0 1.4e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KND95332.1 - 0.00056 19.8 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AftA_N PF12250.3 KND95333.1 - 0.12 11.0 0.4 0.16 10.6 0.3 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal LSR PF05624.9 KND95333.1 - 2.3 8.0 38.0 3.7 7.3 26.3 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Fungal_trans PF04082.13 KND95334.1 - 2.9e-31 108.2 0.1 4.8e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95334.1 - 2.2e-05 24.2 15.5 7.6e-05 22.5 10.7 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.9 KND95334.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Herpes_gE PF02480.11 KND95335.1 - 2.5e-05 22.7 0.1 4.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KND95335.1 - 5.9e-05 23.3 0.0 0.00093 19.5 0.0 2.5 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 KND95335.1 - 0.00021 20.7 0.2 0.00044 19.7 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 KND95335.1 - 0.00042 20.0 0.2 0.00095 18.8 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF1191 PF06697.7 KND95335.1 - 0.0044 15.8 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DAP10 PF07213.6 KND95335.1 - 0.02 14.6 0.6 0.063 13.0 0.1 2.0 2 0 0 2 2 2 0 DAP10 membrane protein DUF1517 PF07466.6 KND95335.1 - 0.045 12.7 0.5 0.1 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Granulin PF00396.13 KND95335.1 - 0.72 10.0 27.3 0.046 13.8 2.7 3.4 2 1 0 2 2 2 0 Granulin PI-PLC-X PF00388.14 KND95336.1 - 6.7e-12 45.0 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain F-box-like PF12937.2 KND95337.1 - 1.3e-06 28.0 0.1 3.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND95337.1 - 0.021 14.4 0.2 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 F-box domain Fungal_trans_2 PF11951.3 KND95338.1 - 9.8e-81 271.2 0.3 1.2e-80 270.9 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95338.1 - 2.1e-08 33.9 6.3 4.3e-08 32.9 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 KND95339.1 - 8.5e-30 102.2 38.4 1.1e-09 37.7 0.4 11.5 10 3 3 13 13 13 8 TPR repeat TPR_1 PF00515.23 KND95339.1 - 8.2e-23 79.0 31.0 8.3e-05 22.0 0.1 12.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.12 KND95339.1 - 9.5e-23 78.2 33.6 0.00029 20.5 0.1 12.9 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_12 PF13424.1 KND95339.1 - 1e-19 70.2 23.8 2.1e-05 24.3 0.7 9.6 7 3 4 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.1 KND95339.1 - 8.5e-19 65.8 9.6 0.00085 18.9 0.0 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 KND95339.1 - 1.6e-16 58.7 23.5 0.00021 20.8 0.1 12.0 13 1 0 13 13 12 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND95339.1 - 4.9e-16 57.7 26.4 0.00038 20.8 0.0 13.2 10 3 3 14 14 13 4 Tetratricopeptide repeat TPR_19 PF14559.1 KND95339.1 - 1.2e-14 54.3 30.9 0.00032 20.9 0.1 10.3 8 3 3 12 12 11 6 Tetratricopeptide repeat TPR_6 PF13174.1 KND95339.1 - 1.9e-10 40.4 23.8 0.024 15.1 0.0 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 KND95339.1 - 8.8e-10 38.9 39.9 0.035 14.7 0.0 10.8 10 3 2 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 KND95339.1 - 9.2e-10 37.9 9.6 0.15 12.3 0.1 10.8 10 1 1 11 11 11 1 Tetratricopeptide repeat Apc3 PF12895.2 KND95339.1 - 2.2e-09 37.3 17.1 0.033 14.3 0.5 7.3 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KND95339.1 - 1.1e-08 34.6 10.3 0.35 10.8 0.0 9.5 11 0 0 11 11 11 2 Tetratricopeptide repeat SNF2_N PF00176.18 KND95340.1 - 8.5e-63 211.9 0.0 1.6e-62 211.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KND95340.1 - 5.4e-27 93.2 8.6 9.2e-16 57.2 0.8 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KND95340.1 - 5.9e-14 51.6 0.0 1.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KND95340.1 - 1.5e-08 34.7 0.0 5.8e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) MaoC_dehydratas PF01575.14 KND95341.1 - 1.5e-20 72.8 0.0 3.9e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain CAP_GLY PF01302.20 KND95341.1 - 6e-20 70.7 0.0 1.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KND95341.1 - 7.5e-15 54.1 0.3 0.0025 17.3 0.0 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND95341.1 - 1.1e-10 41.0 2.6 0.0018 17.9 1.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat MaoC_dehydrat_N PF13452.1 KND95341.1 - 3.3e-07 30.1 0.0 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase LRR_1 PF00560.28 KND95341.1 - 4.1e-06 26.0 0.5 3.2 8.1 0.0 6.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KND95341.1 - 5.1e-06 25.8 6.0 6 7.5 0.1 5.9 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 KND95341.1 - 9.2e-06 25.2 2.8 7.3 7.0 0.0 6.6 7 0 0 7 7 7 1 Leucine Rich repeat LRR_9 PF14580.1 KND95341.1 - 0.00023 20.7 0.2 0.16 11.4 0.0 3.2 2 1 1 3 3 3 2 Leucine-rich repeat DUF3670 PF12419.3 KND95341.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 SNF2 Helicase protein DUF1649 PF07855.7 KND95343.1 - 2.3e-40 137.9 0.0 2.9e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Mo-co_dimer PF03404.11 KND95343.1 - 0.037 13.6 0.1 0.053 13.1 0.1 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Spherulin4 PF12138.3 KND95344.1 - 8.8e-41 139.9 0.2 1e-40 139.7 0.2 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 ATP_bind_1 PF03029.12 KND95345.1 - 5.6e-71 238.8 0.0 9.2e-71 238.1 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KND95345.1 - 3.8e-05 24.5 0.0 0.00011 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND95345.1 - 0.0018 18.1 0.0 0.0038 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KND95345.1 - 0.0032 16.9 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KND95345.1 - 0.007 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND95345.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KND95345.1 - 0.0087 16.0 0.0 0.034 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KND95345.1 - 0.009 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.22 KND95345.1 - 0.0096 15.3 0.0 3.8 6.9 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KND95345.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 KND95345.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KND95345.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KND95345.1 - 0.031 14.5 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KND95345.1 - 0.042 13.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 KND95345.1 - 0.059 12.7 0.1 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase CbiA PF01656.18 KND95345.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 KND95345.1 - 0.075 12.4 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KND95345.1 - 0.076 12.4 0.2 0.26 10.6 0.0 2.0 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 KND95345.1 - 0.097 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KND95345.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KND95345.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KND95345.1 - 0.13 12.5 0.3 0.77 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain S-AdoMet_synt_C PF02773.11 KND95346.1 - 9.1e-76 252.1 0.2 2e-75 251.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KND95346.1 - 5.4e-48 161.9 0.0 9e-48 161.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KND95346.1 - 1.5e-42 143.8 0.5 3.1e-42 142.8 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain MSP1b PF03429.8 KND95346.1 - 0.12 10.2 0.0 0.22 9.3 0.0 1.3 1 0 0 1 1 1 0 Major surface protein 1B PX PF00787.19 KND95347.1 - 3.8e-20 71.7 0.0 1.8e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KND95347.1 - 6.9e-14 51.6 6.8 9.7e-08 31.5 0.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 KND95347.1 - 0.021 14.0 0.4 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF1675 PF07897.6 KND95347.1 - 0.72 9.6 6.0 0.074 12.9 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) MSC PF09402.5 KND95349.1 - 8.8e-101 336.9 0.0 1.3e-100 336.3 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KND95349.1 - 4.2e-15 54.9 0.1 7.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 KND95349.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein DUF3637 PF12337.3 KND95349.1 - 0.032 14.2 0.0 0.094 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) DUF3350 PF11830.3 KND95349.1 - 0.041 13.9 6.1 0.55 10.2 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) Mt_ATP-synt_B PF05405.9 KND95350.1 - 3.1e-55 186.1 6.6 4.7e-55 185.4 4.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) VPS9 PF02204.13 KND95351.1 - 3.2e-27 94.5 0.0 5.4e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KND95351.1 - 3.6e-08 32.7 0.1 3.5e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain TRP PF06011.7 KND95352.1 - 2.8e-136 454.5 12.5 3.5e-136 454.2 8.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND95352.1 - 4.2e-39 133.8 2.4 7.8e-39 132.9 1.7 1.4 1 0 0 1 1 1 1 ML-like domain ETRAMP PF09716.5 KND95352.1 - 9.9 6.1 6.4 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Sod_Cu PF00080.15 KND95353.1 - 3.7e-18 66.0 0.0 4.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) FAM165 PF14981.1 KND95355.1 - 0.088 12.3 0.5 0.2 11.1 0.4 1.6 1 0 0 1 1 1 0 FAM165 family Adeno_E3B PF03376.9 KND95355.1 - 2.7 7.9 6.3 0.22 11.4 0.2 2.3 2 1 1 3 3 3 0 Adenovirus E3B protein COX14 PF14880.1 KND95355.1 - 4.9 6.8 7.2 2 8.0 1.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Glucosamine_iso PF01182.15 KND95357.1 - 2.2e-59 200.5 0.0 2.7e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF846 PF05832.7 KND95358.1 - 2.1e-51 173.3 12.9 2.5e-51 173.1 8.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 KND95358.1 - 0.021 13.9 10.9 0.12 11.5 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Tic20 PF09685.5 KND95358.1 - 1.2 9.1 15.9 0.12 12.3 1.7 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF2530 PF10745.4 KND95358.1 - 1.7 8.7 5.9 0.81 9.7 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Wzy_C PF04932.10 KND95358.1 - 4.8 6.9 10.7 0.89 9.3 2.1 2.1 2 0 0 2 2 2 0 O-Antigen ligase HpcH_HpaI PF03328.9 KND95361.1 - 8.5e-46 155.5 0.2 2e-45 154.3 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KND95361.1 - 6.1e-13 48.3 0.1 6.9e-07 28.4 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.13 KND95361.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain DUF448 PF04296.8 KND95361.1 - 0.12 11.9 0.1 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Acylphosphatase PF00708.13 KND95362.1 - 4.9e-23 81.0 0.1 5.2e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase OB_NTP_bind PF07717.11 KND95363.1 - 5.2e-26 90.7 0.0 1.2e-24 86.3 0.0 2.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KND95363.1 - 4.9e-25 87.5 0.0 4.9e-25 87.5 0.0 2.3 3 0 0 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KND95363.1 - 4.4e-12 45.7 0.0 1.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND95363.1 - 9e-07 28.5 0.0 2.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND95363.1 - 7.1e-05 22.9 0.1 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KND95363.1 - 0.00021 21.1 0.1 0.15 11.9 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KND95363.1 - 0.0011 17.9 0.0 0.0025 16.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KND95363.1 - 0.01 15.2 0.2 0.024 14.1 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KND95363.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain GAD PF02938.9 KND95363.1 - 0.021 14.9 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 GAD domain AAA_14 PF13173.1 KND95363.1 - 0.039 13.8 0.1 0.28 11.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND95363.1 - 0.048 13.9 0.1 0.21 11.8 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_10 PF12846.2 KND95363.1 - 0.055 12.8 0.3 9.9 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KND95363.1 - 0.058 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1363 PF07101.6 KND95363.1 - 0.077 13.0 0.2 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) zf-RING_5 PF14634.1 KND95364.1 - 3.7 7.3 9.2 13 5.6 6.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Hep_59 PF07052.6 KND95365.1 - 3.6e-08 33.6 0.4 3.2e-07 30.6 0.0 2.5 1 1 2 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 zf-HYPF PF07503.7 KND95366.1 - 0.018 14.4 0.8 0.043 13.2 0.5 1.6 1 0 0 1 1 1 0 HypF finger EF-hand_1 PF00036.27 KND95367.1 - 4.5e-24 81.8 9.4 2e-07 29.8 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KND95367.1 - 3.1e-20 72.0 9.2 3.4e-08 33.5 0.1 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KND95367.1 - 7.1e-19 65.9 9.3 0.00032 20.3 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KND95367.1 - 8.9e-16 57.2 13.0 9.7e-09 34.7 0.1 4.7 2 2 3 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 KND95367.1 - 2.8e-13 48.5 12.4 0.00083 18.5 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KND95367.1 - 0.043 13.7 0.4 3.1 7.7 0.0 3.1 3 1 0 3 3 3 0 EF-hand domain GUN4 PF05419.7 KND95367.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.2 KND95367.1 - 2 8.2 4.0 4.4 7.0 0.1 2.7 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Lactamase_B_3 PF13483.1 KND95368.1 - 1.8e-07 31.0 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 KND95368.1 - 0.00021 20.9 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RRM_1 PF00076.17 KND95369.1 - 2.1e-19 68.8 0.0 3.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95369.1 - 3.9e-14 52.3 0.0 5.9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95369.1 - 2.9e-09 36.6 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.7 KND95370.1 - 5e-37 127.5 0.0 7.9e-37 126.9 0.0 1.4 1 1 0 1 1 1 1 ChaC-like protein SBDS_C PF09377.5 KND95371.1 - 7.7e-51 171.0 0.1 1.2e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KND95371.1 - 1.5e-29 101.6 0.3 2.5e-29 100.8 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TPPII_N PF12583.3 KND95371.1 - 1.8 8.7 6.1 1.3 9.1 2.9 1.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Ribosomal_S13 PF00416.17 KND95372.1 - 1.3e-41 141.3 1.9 1.6e-41 141.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KND95372.1 - 0.0076 14.8 0.0 0.008 14.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 KND95372.1 - 0.076 13.0 0.5 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF2746 PF10874.3 KND95372.1 - 0.098 12.8 0.1 9 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Peptidase_M22 PF00814.20 KND95373.1 - 1e-42 146.4 7.5 5.4e-29 101.5 4.3 3.0 2 1 0 2 2 2 2 Glycoprotease family Proteasome PF00227.21 KND95374.1 - 1.6e-48 164.5 0.2 1.9e-48 164.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KND95374.1 - 0.0021 17.2 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF554) DUF3222 PF11519.3 KND95374.1 - 0.029 14.3 0.5 6.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Glyco_hydro_16 PF00722.16 KND95375.1 - 8.1e-11 41.5 0.0 4.7e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 KND95375.1 - 0.0024 17.3 0.5 0.07 12.7 0.1 2.8 2 0 0 2 2 2 1 Adenoviral fibre protein (repeat/shaft region) Glyco_transf_34 PF05637.7 KND95376.1 - 1.6e-13 50.7 0.1 1.9e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MFS_2 PF13347.1 KND95377.1 - 0.0012 17.2 15.7 0.0087 14.4 10.8 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein SOBP PF15279.1 KND95380.1 - 0.17 12.2 1.9 0.19 12.0 1.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Dicty_REP PF05086.7 KND95380.1 - 8.7 3.9 8.3 9.8 3.7 5.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1932 PF09130.6 KND95381.1 - 1.6e-19 69.3 0.2 4.6e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 KND95381.1 - 1.2e-08 35.2 0.1 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KND95381.1 - 2.2e-06 27.6 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KND95381.1 - 0.004 16.8 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KND95381.1 - 0.0041 16.8 0.5 0.0073 16.0 0.3 1.4 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.14 KND95381.1 - 0.0042 16.2 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KND95381.1 - 0.027 14.4 0.8 1.1 9.2 0.0 2.4 2 1 0 2 2 2 0 NADH(P)-binding PDH PF02153.12 KND95381.1 - 0.046 12.6 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Crystall_3 PF08964.5 KND95383.1 - 0.038 13.7 0.1 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin Pertussis_S1 PF02917.9 KND95383.1 - 0.19 11.2 0.9 9.8 5.6 0.2 2.0 1 1 1 2 2 2 0 Pertussis toxin, subunit 1 RRM_1 PF00076.17 KND95384.1 - 6.4e-18 64.1 0.0 1.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95384.1 - 7.1e-13 48.3 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95384.1 - 1.9e-08 33.9 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND95385.1 - 7.2e-18 63.9 0.0 1.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95385.1 - 7.9e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95385.1 - 2.2e-08 33.8 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 KND95386.1 - 1.1e-30 105.9 0.0 1.3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND95386.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Dioxygenase_C PF00775.16 KND95386.1 - 0.023 13.9 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Dioxygenase Anp1 PF03452.9 KND95387.1 - 2.3e-109 364.7 0.0 2.9e-109 364.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KND95387.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PRA1 PF03208.14 KND95388.1 - 3.1e-39 133.7 1.2 4.7e-39 133.1 0.8 1.2 1 0 0 1 1 1 1 PRA1 family protein tRNA-synt_1 PF00133.17 KND95390.1 - 3.2e-217 722.2 0.1 2.5e-216 719.3 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KND95390.1 - 1.2e-33 116.0 0.7 3.6e-33 114.4 0.5 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KND95390.1 - 1.9e-15 56.4 0.2 3.2e-06 26.0 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KND95390.1 - 2e-12 46.8 5.4 2.8e-10 39.8 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KND95390.1 - 9.7e-06 25.5 4.9 9.7e-06 25.5 3.4 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DUF4415 PF14384.1 KND95390.1 - 0.018 15.1 1.1 2.2 8.4 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4415) tRNA-synt_1e PF01406.14 KND95390.1 - 0.069 12.2 1.1 0.72 8.9 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF3464 PF11947.3 KND95390.1 - 1.5 8.2 8.4 3.3 7.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464)