# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF3605 PF12239.8 OAI95151.1 - 7e-07 29.7 0.0 8.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) RHH_1 PF01402.21 OAI95152.1 - 5.8e-07 29.2 3.1 6.1e-07 29.2 0.6 2.1 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family TraY PF05509.11 OAI95152.1 - 2.1e-05 24.4 0.9 4.7e-05 23.3 0.9 1.5 1 0 0 1 1 1 1 TraY domain HicB PF05534.12 OAI95152.1 - 0.027 14.3 0.1 0.071 13.0 0.1 1.7 1 0 0 1 1 1 0 HicB family FAS_I_H PF18314.1 OAI95154.1 - 1.7e-57 194.3 0.8 2.1e-57 194.0 0.8 1.1 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAI95154.1 - 8.6e-42 143.2 0.0 1.3e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain GyrB_insert PF18053.1 OAI95154.1 - 0.033 14.1 0.5 0.55 10.1 0.2 2.2 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain DDE_Tnp_4 PF13359.6 OAI95155.1 - 1.9e-22 79.6 0.0 2.5e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAI95155.1 - 3.3e-06 26.9 0.0 6.5e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAI95155.1 - 0.003 17.2 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein BCA_ABC_TP_C PF12399.8 OAI95155.1 - 0.029 14.3 0.3 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DDE_Tnp_1_2 PF13586.6 OAI95155.1 - 0.048 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain BLUF PF04940.12 OAI95159.1 - 4.2e-29 100.5 0.0 6.6e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD PRA-PH PF01503.17 OAI95164.1 - 2.2e-12 47.2 0.2 4.6e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OAI95164.1 - 0.00023 21.2 0.1 0.00034 20.7 0.1 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 OAI95164.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 MazG-like family TonB_dep_Rec PF00593.24 OAI95165.1 - 8.5e-52 177.6 21.8 1e-51 177.3 21.8 1.0 1 0 0 1 1 1 1 TonB dependent receptor EAP30 PF04157.16 OAI95168.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family DsbC PF11412.8 OAI95177.1 - 9.1e-21 74.1 0.0 1.2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC DsbD PF02683.15 OAI95177.1 - 9.9e-14 51.7 16.3 1.2e-13 51.4 16.3 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 OAI95177.1 - 1.1e-10 41.8 23.0 1.5e-10 41.4 23.0 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Sigma70_r2 PF04542.14 OAI95188.1 - 2.7e-15 55.9 0.1 4.8e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 OAI95188.1 - 4.7e-15 55.0 0.1 1.6e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 OAI95188.1 - 2.5e-07 30.1 0.0 4.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 OAI95188.1 - 8.4e-05 22.5 0.0 9.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor DUF134 PF02001.16 OAI95188.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 GerE PF00196.19 OAI95188.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF4347 PF14252.6 OAI95195.1 - 7.5e-52 175.5 2.1 1e-51 175.0 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) DUF572 PF04502.13 OAI95200.1 - 0.61 9.7 11.5 0.92 9.1 11.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4718 PF15842.5 OAI95200.1 - 1 9.1 7.7 1.8 8.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Macoilin PF09726.9 OAI95200.1 - 1.3 7.5 7.8 1.6 7.2 7.8 1.3 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OAI95200.1 - 4.1 6.9 30.0 9.1 5.8 30.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 OAI95200.1 - 6.3 5.5 4.7 7.6 5.2 4.7 1.1 1 0 0 1 1 1 0 Presenilin SnoaL_2 PF12680.7 OAI95208.1 - 0.00014 22.4 0.0 0.00037 21.1 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 OAI95209.1 - 1.9e-13 50.1 20.8 2.1e-13 49.9 20.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0060 PF02694.15 OAI95209.1 - 0.71 10.1 9.0 5.7 7.2 0.3 2.5 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Peptidase_S64 PF08192.11 OAI95215.1 - 0.26 9.7 15.9 0.12 10.9 9.0 2.0 2 0 0 2 2 2 0 Peptidase family S64 Macoilin PF09726.9 OAI95215.1 - 4.9 5.6 18.5 3.8 6.0 17.2 1.4 1 1 0 1 1 1 0 Macoilin family SLC12 PF03522.15 OAI95215.1 - 5.6 5.9 14.9 1.2 8.1 6.3 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Cyt-b5 PF00173.28 OAI95218.1 - 2.5e-20 72.4 0.1 3.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GlcNAc_2-epim PF07221.11 OAI95221.1 - 1.9e-48 165.5 0.1 2.3e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) S-methyl_trans PF02574.16 OAI95222.1 - 7.6e-15 55.4 0.0 9.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Trns_repr_metal PF02583.17 OAI95224.1 - 9.8e-22 77.1 0.4 1.1e-21 77.0 0.4 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor Pkinase PF00069.25 OAI95228.1 - 1.9e-29 102.9 0.0 2.3e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI95228.1 - 3.8e-17 62.4 0.0 4.9e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAI95228.1 - 6.9e-06 25.6 0.0 9.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HATPase_c PF02518.26 OAI95233.1 - 8e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAI95233.1 - 9.6e-07 28.8 0.4 2.5e-06 27.4 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Nuc_deoxyrib_tr PF05014.15 OAI95233.1 - 0.017 15.2 0.3 0.073 13.1 0.0 2.1 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase HATPase_c_3 PF13589.6 OAI95233.1 - 0.048 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase B12-binding PF02310.19 OAI95233.1 - 0.058 13.4 0.2 5.4 7.1 0.2 2.5 1 1 0 1 1 1 0 B12 binding domain HATPase_c_5 PF14501.6 OAI95233.1 - 0.1 12.5 0.0 0.49 10.3 0.0 2.1 1 1 0 1 1 1 0 GHKL domain RT_RNaseH_2 PF17919.1 OAI95239.1 - 2.8e-32 110.7 0.0 4.5e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI95239.1 - 3.1e-28 98.1 0.0 5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI95239.1 - 2.5e-14 53.3 0.0 5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) R3H PF01424.22 OAI95239.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 R3H domain Afi1 PF07792.12 OAI95243.1 - 4.5e-26 91.9 0.1 2.6e-24 86.2 0.1 2.2 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OAI95243.1 - 2.7e-06 26.3 0.0 1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 OAI95243.1 - 0.099 12.2 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FSA_C PF10479.9 OAI95243.1 - 4.6 5.2 5.9 6.3 4.8 5.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Calici_PP_N PF08405.11 OAI95246.1 - 0.085 11.7 0.0 13 4.5 0.0 2.7 2 1 0 2 2 2 0 Viral polyprotein N-terminal PCuAC PF04314.13 OAI95250.1 - 0.0009 19.0 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C Glyco_hydro_9 PF00759.19 OAI95259.1 - 5.4e-24 85.4 0.5 3.4e-11 43.2 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 PP2C PF00481.21 OAI95259.1 - 1.2e-07 31.6 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Peripla_BP_6 PF13458.6 OAI95267.1 - 9.7e-21 74.8 1.4 1.1e-20 74.6 1.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 OAI95267.1 - 0.00035 19.7 0.0 0.00043 19.4 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Regnase_1_C PF18561.1 OAI95267.1 - 0.21 11.3 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain DUF3435 PF11917.8 OAI95268.1 - 4.2e-12 45.7 0.0 5.4e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Myc_N PF01056.18 OAI95271.1 - 0.0026 17.7 0.2 0.0027 17.7 0.2 1.0 1 0 0 1 1 1 1 Myc amino-terminal region TIMELESS_C PF05029.13 OAI95271.1 - 0.01 15.1 0.5 0.011 15.0 0.5 1.0 1 0 0 1 1 1 1 Timeless protein C terminal region PBP1_TM PF14812.6 OAI95271.1 - 0.026 14.9 0.2 0.037 14.4 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 OAI95271.1 - 0.027 15.0 2.2 0.038 14.6 2.2 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Prok-TraM PF09228.10 OAI95271.1 - 0.035 14.5 0.1 0.042 14.2 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Cnd2 PF05786.14 OAI95271.1 - 0.058 12.1 0.6 0.066 11.9 0.6 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Asp_protease_2 PF13650.6 OAI95276.1 - 0.00015 22.4 0.0 0.00038 21.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI95276.1 - 0.026 15.1 0.1 0.11 13.1 0.0 2.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI95276.1 - 0.14 12.5 0.0 0.7 10.2 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1302 PF06980.11 OAI95278.1 - 5e-61 207.0 2.1 1.4e-60 205.5 2.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1302) E1_dh PF00676.20 OAI95281.1 - 9.7e-38 129.8 0.0 1.1e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component ACR_tran PF00873.19 OAI95282.1 - 1.9e-85 287.4 0.6 2.1e-85 287.3 0.6 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family NP1-WLL PF11733.8 OAI95285.1 - 3.5 7.3 5.4 0.19 11.5 0.3 1.5 2 0 0 2 2 2 0 Non-capsid protein NP1 P-II PF00543.22 OAI95292.1 - 0.059 14.0 0.0 0.067 13.8 0.0 1.1 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II DUF1538 PF07556.11 OAI95293.1 - 1.4e-55 187.8 13.4 1.7e-55 187.6 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1538) Tad PF13400.6 OAI95293.1 - 0.066 13.5 1.6 0.066 13.5 1.6 3.9 5 0 0 5 5 5 0 Putative Flp pilus-assembly TadE/G-like Histone PF00125.24 OAI95297.1 - 2.3e-18 66.8 0.2 3e-18 66.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAI95297.1 - 1.8e-07 31.3 0.1 2.7e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAI95297.1 - 0.00014 22.3 0.0 0.00019 21.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A NFACT-R_2 PF18297.1 OAI95297.1 - 0.015 15.5 0.1 0.018 15.2 0.1 1.1 1 0 0 1 1 1 0 NFACT protein RNA binding domain TFIID-31kDa PF02291.15 OAI95297.1 - 0.097 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_hydro_18 PF00704.28 OAI95299.1 - 4.6e-11 43.0 0.0 5.1e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IF-2 PF11987.8 OAI95300.1 - 0.073 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 DNA_pol_viral_C PF00336.18 OAI95303.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAI95303.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like MMPL PF03176.15 OAI95307.1 - 0.0025 16.8 6.1 0.0029 16.6 6.1 1.2 1 0 0 1 1 1 1 MMPL family ACR_tran PF00873.19 OAI95307.1 - 0.048 11.3 4.7 0.062 10.9 4.7 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF1635 PF07795.11 OAI95312.1 - 0.59 9.9 7.2 0.81 9.5 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Macoilin PF09726.9 OAI95312.1 - 0.67 8.4 4.6 0.72 8.3 4.6 1.1 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 OAI95312.1 - 1.6 8.1 9.9 2 7.7 9.9 1.1 1 0 0 1 1 1 0 SDA1 Orthopox_A36R PF05950.11 OAI95312.1 - 3.3 7.9 9.6 6.7 6.8 9.6 1.5 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Uds1 PF15456.6 OAI95312.1 - 3.5 7.8 6.9 32 4.7 6.9 2.0 1 1 0 1 1 1 0 Up-regulated During Septation SSP160 PF06933.11 OAI95312.1 - 5.5 5.1 15.3 7.2 4.7 15.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4171 PF13775.6 OAI95313.1 - 0.15 12.5 6.3 0.21 12.0 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) TAF4 PF05236.14 OAI95318.1 - 0.016 15.0 1.7 0.021 14.6 1.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family G_path_suppress PF15991.5 OAI95318.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor AdoHcyase PF05221.17 OAI95318.1 - 0.041 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Macoilin PF09726.9 OAI95318.1 - 0.15 10.6 4.3 0.17 10.4 4.3 1.2 1 0 0 1 1 1 0 Macoilin family CTU2 PF10288.9 OAI95318.1 - 0.28 11.4 4.9 0.18 12.0 2.4 2.0 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-CCHC PF00098.23 OAI95318.1 - 7.5 6.8 6.8 18 5.6 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle RAP1 PF07218.11 OAI95318.1 - 8.4 4.5 9.8 13 3.9 9.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Big_8 PF17961.1 OAI95322.1 - 0.16 12.2 6.0 0.49 10.6 1.1 3.2 3 0 0 3 3 3 0 Bacterial Ig domain Big_9 PF17963.1 OAI95322.1 - 0.55 11.0 52.4 0.34 11.7 14.7 5.0 3 3 0 3 3 3 0 Bacterial Ig domain GFO_IDH_MocA PF01408.22 OAI95326.1 - 1.4e-13 51.8 0.0 2.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAI95326.1 - 0.009 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ACP_syn_III PF08545.10 OAI95326.1 - 0.13 12.1 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hydrolase PF00702.26 OAI95327.1 - 4.9e-26 92.3 2.3 6e-26 92.0 2.3 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAI95327.1 - 5.4e-08 32.9 0.7 3.8e-05 23.6 0.1 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAI95327.1 - 0.0017 18.8 0.1 0.0039 17.6 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_3 PF05977.13 OAI95331.1 - 1.5e-34 119.4 0.1 1.7e-34 119.1 0.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector DUF3134 PF11332.8 OAI95331.1 - 0.11 12.8 0.2 0.22 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) HTH_IclR PF09339.10 OAI95332.1 - 8.6e-08 31.9 0.0 1.8e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 OAI95332.1 - 1.9e-05 24.5 0.0 4.7e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 OAI95332.1 - 0.0018 18.1 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 OAI95332.1 - 0.0091 15.5 0.0 0.023 14.3 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 OAI95332.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator zf-CCHC PF00098.23 OAI95340.1 - 0.47 10.6 3.7 0.73 10.0 3.7 1.3 1 0 0 1 1 1 0 Zinc knuckle PAS_3 PF08447.12 OAI95341.1 - 3.7e-10 40.0 0.0 8.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAI95341.1 - 1.3e-08 34.8 0.0 3.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAI95341.1 - 5.2e-07 29.9 0.2 6.3e-06 26.4 0.1 2.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 OAI95341.1 - 0.0002 21.6 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain Sigma54_CBD PF04963.13 OAI95341.1 - 0.091 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain CCDC85 PF10226.9 OAI95341.1 - 0.11 12.2 0.7 0.25 11.0 0.7 1.5 1 0 0 1 1 1 0 CCDC85 family DNA_pol_viral_C PF00336.18 OAI95343.1 - 0.021 14.3 0.1 0.052 13.0 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RT_RNaseH_2 PF17919.1 OAI95343.1 - 0.027 14.5 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF1670 PF07900.11 OAI95343.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) GFO_IDH_MocA PF01408.22 OAI95351.1 - 2.2e-23 83.3 0.0 2.7e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAI95351.1 - 0.0018 18.9 0.1 0.0023 18.6 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAI95351.1 - 0.0062 15.9 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAI95351.1 - 0.038 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 OAI95351.1 - 0.13 12.4 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Astro_capsid_p PF12226.8 OAI95353.1 - 1.8 7.7 9.1 2.7 7.1 9.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAD_binding_2 PF00890.24 OAI95357.1 - 3.9e-14 52.6 0.0 4.2e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain TraC_F_IV PF11130.8 OAI95362.1 - 6.8e-15 55.3 0.0 2.2e-12 47.1 0.0 2.5 1 1 1 2 2 2 2 F pilus assembly Type-IV secretion system for plasmid transfer adh_short PF00106.25 OAI95365.1 - 1.2e-32 113.0 0.8 1.3e-32 112.9 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAI95365.1 - 1.8e-26 93.2 1.6 2e-26 93.0 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAI95365.1 - 6.5e-06 26.2 0.6 8.3e-06 25.8 0.6 1.2 1 1 0 1 1 1 1 KR domain TPR_4 PF07721.14 OAI95365.1 - 0.055 14.1 1.3 0.055 14.1 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.26 OAI95378.1 - 5.8e-38 129.7 0.0 6.9e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Toprim_4 PF13662.6 OAI95380.1 - 0.19 12.2 0.0 0.31 11.5 0.0 1.5 1 1 0 1 1 1 0 Toprim domain Phage_integrase PF00589.22 OAI95384.1 - 0.00027 20.8 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAI95384.1 - 0.057 13.2 0.2 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) rve PF00665.26 OAI95385.1 - 7.5e-15 55.2 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI95385.1 - 6.2e-14 51.8 0.2 1.1e-13 51.1 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAI95385.1 - 1.1e-07 32.0 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 OAI95385.1 - 0.0021 17.8 0.0 0.0071 16.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAI95391.1 - 1.1e-23 83.4 0.1 1.5e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SPOB_ab PF14682.6 OAI95395.1 - 0.05 13.7 0.1 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal UPF0183 PF03676.14 OAI95403.1 - 5.2e-18 65.5 0.0 2.2e-05 24.0 0.0 3.0 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) PALP PF00291.25 OAI95405.1 - 9.9e-25 87.5 0.0 1.1e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S41 PF03572.18 OAI95405.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S41 DUF1720 PF08226.11 OAI95409.1 - 0.63 10.5 15.8 7.9 7.0 15.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) TarH PF02203.15 OAI95410.1 - 6.2e-05 23.0 0.9 6.2e-05 23.0 0.9 2.0 2 0 0 2 2 2 1 Tar ligand binding domain homologue HAMP PF00672.25 OAI95410.1 - 0.00032 21.0 1.8 0.00057 20.2 1.0 1.9 2 0 0 2 2 2 1 HAMP domain 4HB_MCP_1 PF12729.7 OAI95410.1 - 0.00038 20.1 0.0 0.00038 20.1 0.0 1.6 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction AsmA PF05170.14 OAI95410.1 - 0.069 11.9 1.2 0.095 11.5 1.2 1.2 1 0 0 1 1 1 0 AsmA family MHC_II_beta PF00969.19 OAI95410.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain HlyD_D23 PF16576.5 OAI95412.1 - 2.2e-16 59.7 2.8 3.2e-16 59.2 2.8 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 OAI95412.1 - 2.7e-13 50.5 1.9 5.6e-08 33.4 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 OAI95412.1 - 1.7e-09 37.4 6.8 2.2e-08 33.8 2.9 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 OAI95412.1 - 0.00035 20.3 0.6 0.056 13.3 0.0 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme V-SNARE_C PF12352.8 OAI95412.1 - 0.0038 17.5 1.7 0.02 15.2 0.4 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus OEP PF02321.18 OAI95412.1 - 0.0039 17.0 16.5 0.0064 16.3 16.5 1.3 1 0 0 1 1 1 1 Outer membrane efflux protein VWA_3_C PF18571.1 OAI95412.1 - 0.0049 16.7 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A C-terminal domain PYNP_C PF07831.13 OAI95412.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Spc7 PF08317.11 OAI95412.1 - 0.32 9.8 4.9 0.42 9.5 4.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_19 PF14559.6 OAI95412.1 - 0.72 10.4 13.0 0.062 13.8 3.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat HlyD PF00529.20 OAI95412.1 - 4.9 7.1 6.1 0.49 10.3 0.1 2.5 3 1 0 3 3 3 0 HlyD membrane-fusion protein of T1SS Herpes_pp85 PF04637.12 OAI95414.1 - 0.14 10.5 2.4 0.27 9.6 2.4 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Phosphoprotein PF00922.17 OAI95414.1 - 0.28 10.7 1.6 0.38 10.3 1.6 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Phage_integrase PF00589.22 OAI95416.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family ThiF PF00899.21 OAI95424.1 - 5.5e-10 39.0 0.0 7.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 OAI95424.1 - 0.0017 18.9 0.1 0.003 18.2 0.1 1.4 1 0 0 1 1 1 1 PglD N-terminal domain Multi_ubiq PF14452.6 OAI95425.1 - 5.1e-12 45.9 0.0 6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Multiubiquitin DUF1840 PF08895.11 OAI95430.1 - 0.0026 18.1 0.1 0.014 15.7 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1840) AMP-binding_C PF13193.6 OAI95431.1 - 5.4e-21 75.3 0.0 6.5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Oxysterol_BP PF01237.18 OAI95433.1 - 1.2e-41 142.8 0.5 5e-39 134.2 0.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein WSD PF15613.6 OAI95433.1 - 0.05 14.1 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF2956 PF11169.8 OAI95433.1 - 0.076 13.2 0.5 0.12 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Serglycin PF04360.12 OAI95436.1 - 0.0006 19.8 1.0 0.0021 18.0 1.0 1.9 1 0 0 1 1 1 1 Serglycin Nop14 PF04147.12 OAI95437.1 - 1.7 6.7 9.6 2.3 6.3 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 OAI95437.1 - 1.8 9.0 7.0 0.16 12.4 1.9 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cellulase PF00150.18 OAI95441.1 - 6.9e-09 35.5 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HsbA PF12296.8 OAI95443.1 - 0.65 10.4 6.9 0.11 12.9 2.8 1.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A RT_RNaseH PF17917.1 OAI95450.1 - 1.3e-06 28.6 0.1 2.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop14 PF04147.12 OAI95450.1 - 2.1 6.4 4.4 2.7 6.1 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family RNase_T PF00929.24 OAI95456.1 - 0.0069 16.9 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 2 Exonuclease ResIII PF04851.15 OAI95458.1 - 9.6e-18 64.8 0.0 2.1e-17 63.7 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAI95458.1 - 7.7e-10 38.8 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 OAI95458.1 - 0.012 14.3 0.1 0.058 12.1 0.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 OAI95458.1 - 0.023 15.0 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Helicase_C PF00271.31 OAI95458.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain CheR PF01739.18 OAI95461.1 - 7e-59 198.6 0.0 1e-58 198.0 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 OAI95461.1 - 2.8e-11 43.0 1.6 5.7e-11 42.0 1.6 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Response_reg PF00072.24 OAI95461.1 - 2e-08 34.4 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_25 PF13649.6 OAI95461.1 - 0.00033 21.3 0.0 0.018 15.7 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAI95461.1 - 0.00038 21.2 0.0 0.0019 18.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Dicer_dimer PF03368.14 OAI95463.1 - 9.9e-20 70.5 0.1 1.9e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 OAI95463.1 - 0.0011 19.6 0.0 0.0035 18.0 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif Retrotran_gag_2 PF14223.6 OAI95467.1 - 1.8e-16 60.1 0.1 2.4e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 OAI95467.1 - 0.017 15.0 1.4 0.049 13.6 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 OAI95467.1 - 0.033 13.9 3.5 4.6 7.1 1.7 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 OAI95467.1 - 0.034 14.2 2.6 0.034 14.2 2.6 3.2 3 1 0 3 3 3 0 Zinc knuckle GHMP_kinases_C PF08544.13 OAI95467.1 - 0.22 11.9 0.7 6.5 7.2 0.1 2.9 3 0 0 3 3 3 0 GHMP kinases C terminal Actin PF00022.19 OAI95469.1 - 6.8e-52 176.4 0.0 8e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Actin PS_pyruv_trans PF04230.13 OAI95477.1 - 7.8e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Epimerase PF01370.21 OAI95481.1 - 2.2e-56 191.1 0.0 2.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAI95481.1 - 2.4e-50 171.8 0.0 2.7e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAI95481.1 - 1.8e-13 50.3 0.0 1.9e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAI95481.1 - 2.9e-12 46.2 0.0 3.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAI95481.1 - 2.2e-09 36.9 0.0 1.2e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAI95481.1 - 4.3e-07 30.0 0.0 9.3e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAI95481.1 - 2.2e-05 23.8 0.0 0.0054 15.9 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 OAI95481.1 - 2.5e-05 23.8 0.0 5.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAI95481.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 OAI95481.1 - 0.0066 16.0 0.0 0.0087 15.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAI95481.1 - 0.22 11.0 0.0 0.48 9.9 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family HypD PF01924.16 OAI95483.1 - 1.8e-140 468.0 0.0 2e-140 467.8 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family DUF4148 PF13663.6 OAI95493.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) MutS_IV PF05190.18 OAI95509.1 - 1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 OAI95509.1 - 0.00019 21.8 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 MutS domain III Orthopox_F6 PF06601.12 OAI95509.1 - 0.051 13.7 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F6 protein DUF4537 PF15057.6 OAI95511.1 - 0.0039 17.2 0.1 0.024 14.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) NAD_binding_8 PF13450.6 OAI95518.1 - 1.6e-15 57.1 2.3 2.3e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAI95518.1 - 2.4e-09 37.0 0.0 2.4e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 OAI95518.1 - 1.7e-07 31.2 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAI95518.1 - 0.0022 17.2 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAI95518.1 - 0.0086 15.3 0.0 0.016 14.5 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAI95518.1 - 0.015 14.6 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAI95518.1 - 0.059 12.1 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein RadC PF04002.15 OAI95522.1 - 3e-40 137.0 0.0 5.4e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 OAI95522.1 - 0.0008 19.2 0.2 0.0013 18.5 0.1 1.4 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Spc7_N PF15402.6 OAI95532.1 - 0.27 9.4 0.7 0.36 9.0 0.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Phage_integrase PF00589.22 OAI95537.1 - 0.00081 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAI95537.1 - 0.31 10.9 0.7 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) An_peroxidase PF03098.15 OAI95540.1 - 0.00086 18.0 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Septin PF00735.18 OAI95543.1 - 1.3e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Septin DUF4581 PF15167.6 OAI95549.1 - 0.09 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) MFS_1 PF07690.16 OAI95551.1 - 2.1e-10 40.1 3.2 2.3e-10 39.9 3.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAI95551.1 - 0.00026 20.0 0.6 0.00026 20.0 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 OAI95551.1 - 0.022 13.2 0.2 0.022 13.2 0.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector DUF2752 PF10825.8 OAI95551.1 - 0.092 12.8 0.9 0.15 12.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) NAD_binding_8 PF13450.6 OAI95552.1 - 2.1e-08 34.2 0.1 3.7e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAI95552.1 - 3.4e-06 26.7 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAI95552.1 - 3.7e-05 23.1 0.1 4.9e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAI95552.1 - 0.00021 21.0 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAI95552.1 - 0.00024 20.3 0.3 0.00034 19.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OAI95552.1 - 0.00065 19.0 0.6 0.00095 18.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 OAI95552.1 - 0.0048 15.7 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 MCRA family HI0933_like PF03486.14 OAI95552.1 - 0.005 15.6 1.0 0.0069 15.1 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 OAI95552.1 - 0.006 15.9 0.0 0.0072 15.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAI95552.1 - 0.021 15.4 0.8 0.038 14.5 0.8 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAI95552.1 - 0.068 12.4 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 OAI95552.1 - 0.1 12.0 0.2 0.71 9.2 0.2 1.9 1 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_3 PF13738.6 OAI95552.1 - 0.27 10.4 1.2 0.38 10.0 1.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CAP_N PF01213.19 OAI95554.1 - 0.24 10.8 2.3 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GMC_oxred_N PF00732.19 OAI95562.1 - 1.4e-27 96.9 0.0 1.8e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAI95562.1 - 8e-05 21.9 0.1 0.00012 21.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAI95562.1 - 0.00013 22.2 0.1 0.00034 20.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAI95562.1 - 0.00051 19.4 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAI95562.1 - 0.0018 17.9 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAI95562.1 - 0.0022 17.2 0.1 0.0037 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAI95562.1 - 0.0034 16.6 0.1 0.0049 16.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAI95562.1 - 0.0096 15.2 0.2 0.016 14.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAI95562.1 - 0.048 13.6 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAI95562.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 OAI95562.1 - 0.17 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MerR-DNA-bind PF09278.11 OAI95564.1 - 0.096 13.2 1.6 0.16 12.6 1.6 1.5 1 1 0 1 1 1 0 MerR, DNA binding PAS_8 PF13188.7 OAI95566.1 - 1.7e-12 47.0 0.2 6e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 OAI95566.1 - 3.1e-12 46.5 0.0 6.8e-08 32.5 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 OAI95566.1 - 1e-10 41.9 0.1 3.8e-07 30.3 0.0 4.1 4 0 0 4 4 4 1 PAS fold GAF_2 PF13185.6 OAI95566.1 - 4e-09 36.9 0.5 6.2e-08 33.0 0.1 2.6 2 1 0 2 2 2 1 GAF domain PAS_9 PF13426.7 OAI95566.1 - 1.3e-07 31.9 0.0 7.5e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 OAI95566.1 - 2.2e-07 31.0 0.0 1.7e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 OAI95566.1 - 0.00047 20.8 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OAI95566.1 - 0.0018 18.6 2.9 0.037 14.4 0.0 3.4 3 1 0 3 3 3 1 GAF domain PMSR PF01625.21 OAI95568.1 - 5.3e-23 81.9 0.6 2.5e-22 79.7 0.6 1.8 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3921 PF13060.6 OAI95568.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) TSC21 PF15217.6 OAI95569.1 - 0.035 14.1 0.1 0.04 13.9 0.1 1.1 1 0 0 1 1 1 0 TSC21 family zf-U1 PF06220.12 OAI95570.1 - 9.7e-16 57.3 3.4 1.4e-15 56.8 3.4 1.2 1 0 0 1 1 1 1 U1 zinc finger TPR_19 PF14559.6 OAI95573.1 - 0.00033 21.1 33.3 0.58 10.7 2.3 6.9 5 2 0 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 OAI95573.1 - 0.0031 18.0 31.0 0.97 10.3 0.6 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAI95573.1 - 0.018 15.2 4.0 8.2 6.9 0.0 5.4 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAI95573.1 - 0.042 14.5 14.0 2.5 8.8 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat FAD-SLDH PF12318.8 OAI95573.1 - 0.044 13.9 0.8 0.044 13.9 0.8 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4363 PF14276.6 OAI95573.1 - 0.1 12.7 3.8 1.1 9.4 1.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) TPR_2 PF07719.17 OAI95573.1 - 0.12 12.6 12.2 17 5.8 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAI95573.1 - 0.14 12.0 2.1 33 4.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAI95573.1 - 0.35 11.0 22.3 3.9 7.7 0.1 6.6 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAI95573.1 - 0.44 11.3 0.1 0.44 11.3 0.1 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAI95573.1 - 0.67 10.3 24.0 0.11 12.8 3.4 5.6 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAI95573.1 - 2.4 8.8 9.7 13 6.5 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAI95573.1 - 7.6 7.6 38.3 0.59 11.1 1.4 7.7 6 2 3 9 9 8 0 Tetratricopeptide repeat Acetyltransf_3 PF13302.7 OAI95575.1 - 1.8e-13 51.4 0.0 2e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAI95575.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CHRD PF07452.12 OAI95576.1 - 3.7e-07 31.1 0.0 4.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 CHRD domain AICARFT_IMPCHas PF01808.18 OAI95580.1 - 1.8e-05 24.3 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme DUF1952 PF09189.10 OAI95583.1 - 0.07 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) RVT_2 PF07727.14 OAI95590.1 - 4.5e-16 59.2 0.0 6.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2CSK_N PF08521.10 OAI95590.1 - 0.077 13.1 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 Two-component sensor kinase N-terminal ICL PF00463.21 OAI95593.1 - 2e-97 326.9 0.0 1.2e-76 258.4 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 OAI95593.1 - 1.2e-09 38.0 0.1 2.5e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 OAI95593.1 - 0.011 15.5 0.9 0.018 14.9 0.1 1.7 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain RVT_1 PF00078.27 OAI95600.1 - 2.6e-16 59.8 0.0 4.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_N PF08240.12 OAI95601.1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF3558 PF12079.8 OAI95602.1 - 0.025 14.6 1.9 0.029 14.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) HD_3 PF13023.6 OAI95605.1 - 0.23 11.4 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 HD domain Phage_int_SAM_1 PF02899.17 OAI95609.1 - 0.029 14.7 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 OAI95611.1 - 0.00047 20.0 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAI95611.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Asn_synthase PF00733.21 OAI95616.1 - 5.4e-05 23.0 0.2 7.4e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 OAI95616.1 - 0.0056 15.8 0.0 0.007 15.5 0.0 1.1 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 OAI95616.1 - 0.082 12.4 0.0 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Ribosomal_60s PF00428.19 OAI95616.1 - 0.12 13.0 2.0 0.21 12.2 2.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.14 OAI95621.1 - 0.25 9.6 12.7 0.38 9.0 12.7 1.4 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 OAI95621.1 - 0.59 9.7 26.2 0.91 9.1 26.0 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PI3K_1B_p101 PF10486.9 OAI95621.1 - 1.4 6.6 6.1 1.9 6.2 6.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CCDC106 PF15794.5 OAI95621.1 - 6.4 6.4 16.4 0.49 10.1 10.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Ribosomal_S19 PF00203.21 OAI95626.1 - 8.6e-32 108.9 0.2 1.1e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 OAI95626.1 - 0.045 13.8 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH DSHCT PF08148.12 OAI95629.1 - 2.4e-16 59.8 0.4 6.7e-16 58.4 0.2 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OAI95629.1 - 1.9e-08 34.6 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain 6PGD PF00393.19 OAI95631.1 - 5.1e-05 22.8 0.1 6.6e-05 22.4 0.1 1.2 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain PDZ_2 PF13180.6 OAI95634.1 - 8.4e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OAI95634.1 - 0.00045 20.0 0.1 0.00071 19.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAI95634.1 - 0.014 15.8 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 PDZ domain DUF3394 PF11874.8 OAI95634.1 - 0.048 13.3 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) PAS_4 PF08448.10 OAI95642.1 - 7e-20 71.3 1.2 4.7e-09 36.5 0.0 4.4 4 1 0 4 4 4 3 PAS fold PAS PF00989.25 OAI95642.1 - 1.2e-09 38.2 0.1 0.0014 18.6 0.0 3.9 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.7 OAI95642.1 - 5.9e-09 35.7 0.7 0.016 15.3 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 OAI95642.1 - 1.5e-08 34.8 0.0 0.00074 19.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAI95642.1 - 3.1e-06 27.4 0.0 3.8 7.8 0.0 4.4 4 1 0 4 4 4 3 PAS domain PAS_7 PF12860.7 OAI95642.1 - 2.9e-05 24.2 0.2 0.86 9.8 0.1 3.8 3 1 0 3 3 3 2 PAS fold Cytochrome_CBB3 PF13442.6 OAI95643.1 - 2.1e-15 56.8 0.0 3.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAI95643.1 - 5.9e-06 27.3 0.5 6.3e-05 24.0 0.5 2.2 1 1 0 1 1 1 1 Cytochrome c DUF1952 PF09189.10 OAI95645.1 - 0.0048 16.7 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1952) Pro_isomerase PF00160.21 OAI95649.1 - 2e-49 167.9 0.4 2.5e-49 167.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PRIMA1 PF16101.5 OAI95663.1 - 1.2 9.2 3.3 2.2 8.3 3.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AMP-binding PF00501.28 OAI95665.1 - 1.5e-53 181.9 0.0 1.6e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.27 OAI95676.1 - 1.6e-06 27.8 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sel1 PF08238.12 OAI95679.1 - 0.00021 21.9 14.9 0.032 14.9 0.1 5.6 6 0 0 6 6 6 2 Sel1 repeat DUF2587 PF10759.9 OAI95679.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TPR_2 PF07719.17 OAI95679.1 - 0.37 11.0 0.0 0.37 11.0 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF35_N PF12172.8 OAI95681.1 - 0.045 13.6 8.9 4.8 7.2 0.1 5.5 5 0 0 5 5 5 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MetallophosN PF16371.5 OAI95681.1 - 1.3 9.4 7.8 3.6 7.9 0.1 5.5 5 3 4 9 9 9 0 N terminal of Calcineurin-like phosphoesterase cEGF PF12662.7 OAI95681.1 - 2.9 7.9 93.2 0.33 10.9 0.9 13.6 14 0 0 14 14 14 0 Complement Clr-like EGF-like CHASE PF03924.13 OAI95684.1 - 2.2e-52 177.7 0.4 3.1e-52 177.3 0.4 1.2 1 0 0 1 1 1 1 CHASE domain DUF4381 PF14316.6 OAI95684.1 - 1.2 9.4 4.7 2 8.7 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) adh_short_C2 PF13561.6 OAI95687.1 - 3.7e-15 56.1 0.0 5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyoxalase PF00903.25 OAI95687.1 - 1.6e-10 41.3 1.2 5.1e-08 33.2 0.3 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1325 PF07039.11 OAI95691.1 - 1.7e-10 41.1 0.0 5.9e-10 39.3 0.0 1.8 1 1 1 2 2 2 1 SGF29 tudor-like domain IstB_IS21 PF01695.17 OAI95697.1 - 1.5e-34 119.3 0.0 2.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein rve PF00665.26 OAI95697.1 - 1.9e-13 50.6 0.0 3.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain PhoH PF02562.16 OAI95697.1 - 3e-06 26.9 0.0 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 OAI95697.1 - 0.00061 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 OAI95697.1 - 0.00078 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB rve_3 PF13683.6 OAI95697.1 - 0.0012 18.6 0.1 0.0092 15.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Bac_DnaA PF00308.18 OAI95697.1 - 0.0025 17.7 0.0 0.0074 16.2 0.0 1.7 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_25 PF13481.6 OAI95697.1 - 0.0036 16.9 0.1 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAI95697.1 - 0.017 15.5 0.1 0.052 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 OAI95697.1 - 0.036 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAI95697.1 - 0.044 14.1 0.1 0.21 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OAI95697.1 - 0.044 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 OAI95697.1 - 0.055 13.2 0.1 0.21 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAI95697.1 - 0.058 13.9 0.2 0.37 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OAI95697.1 - 0.081 13.4 0.0 0.37 11.3 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 OAI95697.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAI95697.1 - 0.23 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Phage_integrase PF00589.22 OAI95702.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Rib_5-P_isom_A PF06026.14 OAI95708.1 - 4.2e-53 179.5 0.0 5e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF211 PF02680.14 OAI95708.1 - 0.028 14.6 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 MarR_2 PF12802.7 OAI95709.1 - 3.2e-08 33.3 0.9 6.6e-08 32.3 0.4 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 OAI95709.1 - 9.1e-06 25.5 0.0 2.1e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 MarR family CDC27 PF09507.10 OAI95714.1 - 0.1 12.0 2.8 0.12 11.8 2.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CorA PF01544.18 OAI95716.1 - 2.5e-30 105.8 0.0 3.1e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GST_N PF02798.20 OAI95716.1 - 3.6e-10 40.0 0.0 6.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAI95716.1 - 4.3e-07 30.2 0.0 9.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAI95716.1 - 1.8e-06 28.3 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAI95716.1 - 8.2e-05 22.8 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAI95716.1 - 0.0035 17.3 0.2 0.015 15.3 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.31 OAI95717.1 - 6.4e-07 29.7 0.0 2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rve PF00665.26 OAI95719.1 - 3e-14 53.2 0.0 4.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAI95719.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Abhydrolase_4 PF08386.10 OAI95720.1 - 7.6e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 OAI95720.1 - 9e-06 26.4 0.1 1e-05 26.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAI95720.1 - 0.04 13.6 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold HOIP-UBA PF16678.5 OAI95724.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 HOIP UBA domain pair UBA PF00627.31 OAI95724.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Glycos_transf_2 PF00535.26 OAI95729.1 - 1.1e-29 103.4 0.0 1.5e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAI95729.1 - 2.2e-11 44.1 0.0 3.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAI95729.1 - 3.6e-07 29.9 0.0 5.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OAI95729.1 - 0.0023 18.4 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.25 OAI95735.1 - 3.8e-24 85.5 0.0 5.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI95735.1 - 7.8e-14 51.6 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAI95735.1 - 0.00056 19.3 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like U3snoRNP10 PF12397.8 OAI95737.1 - 0.0011 19.3 0.1 0.0026 18.1 0.1 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 HD_5 PF13487.6 OAI95737.1 - 0.0094 16.2 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 HD domain HTH_Tnp_4 PF13613.6 OAI95742.1 - 0.00082 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 OAI95742.1 - 0.0012 18.6 0.1 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 OAI95742.1 - 0.0013 18.6 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 OAI95742.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 OAI95742.1 - 0.0045 17.1 0.3 0.027 14.6 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 OAI95742.1 - 0.0071 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.13 OAI95742.1 - 0.01 15.5 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 OAI95742.1 - 0.054 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 OAI95742.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 OAI95742.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TnsD PF15978.5 OAI95742.1 - 0.096 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D LacI PF00356.21 OAI95742.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.10 OAI95742.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Crp PF00325.20 OAI95742.1 - 0.16 11.7 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family RVT_1 PF00078.27 OAI95749.1 - 1.9e-05 24.3 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Porin_5 PF16930.5 OAI95749.1 - 0.14 10.6 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative porin DUF4855 PF16147.5 OAI95753.1 - 0.12 11.4 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) Mur_ligase_C PF02875.21 OAI95757.1 - 0.052 13.8 0.1 0.93 9.8 0.1 2.5 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain PTS_EIIA_2 PF00359.22 OAI95761.1 - 9.1e-17 61.3 0.4 2.1e-13 50.4 0.0 2.3 1 1 1 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Ribosom_S30AE_C PF16321.5 OAI95761.1 - 6.2e-13 48.2 0.0 1.8e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Methyltransf_11 PF08241.12 OAI95761.1 - 0.045 14.4 0.1 0.45 11.2 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain Sdh5 PF03937.16 OAI95761.1 - 0.075 13.0 0.2 1 9.4 0.2 2.4 1 1 0 1 1 1 0 Flavinator of succinate dehydrogenase GrpE PF01025.19 OAI95762.1 - 3.3e-47 160.2 0.1 3.8e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 GrpE Rep_3 PF01051.21 OAI95768.1 - 4.5e-25 88.8 0.0 5.5e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Initiator Replication protein WXG100 PF06013.12 OAI95768.1 - 0.044 14.0 0.5 0.16 12.2 0.0 2.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ECH_1 PF00378.20 OAI95771.1 - 7.5e-12 45.1 0.1 9.3e-12 44.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAI95771.1 - 0.00061 19.4 0.2 0.0018 17.9 0.2 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Clathrin_H_link PF13838.6 OAI95772.1 - 2.8e-29 100.8 0.0 4.3e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin-H-link Pyr_redox_3 PF13738.6 OAI95774.1 - 7.6e-12 45.1 0.0 9.9e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAI95774.1 - 1.6e-10 40.0 0.0 2.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAI95774.1 - 2.5e-08 33.4 0.0 4.2e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAI95774.1 - 4.4e-06 26.1 0.0 5.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAI95774.1 - 0.025 14.1 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAI95774.1 - 0.078 11.7 0.0 0.17 10.5 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 OAI95774.1 - 0.086 12.2 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAI95774.1 - 0.12 12.3 0.2 2.8 7.9 0.0 2.6 2 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 OAI95774.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Retrotran_gag_2 PF14223.6 OAI95782.1 - 6.7e-23 80.9 0.1 9.1e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 OAI95782.1 - 0.00019 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAI95782.1 - 0.0039 16.8 0.2 0.016 14.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) eIF3g PF12353.8 OAI95782.1 - 0.016 15.6 0.6 0.03 14.7 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RBFA PF02033.18 OAI95782.1 - 0.091 13.2 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A GH97_C PF14509.6 OAI95785.1 - 4.4e-27 94.1 0.0 5.6e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-hydrolase 97 C-terminal, oligomerisation Glyco_hydro_97 PF10566.9 OAI95785.1 - 6.5e-14 51.9 0.0 8.5e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 MFS_1 PF07690.16 OAI95786.1 - 2.4e-11 43.2 15.9 3e-11 42.8 15.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MOZ_SAS PF01853.18 OAI95786.1 - 0.09 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 MOZ/SAS family VEK-30 PF12107.8 OAI95786.1 - 0.29 11.1 0.5 0.63 10.0 0.5 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway MFS_2 PF13347.6 OAI95786.1 - 0.56 8.7 16.4 1.1 7.7 16.5 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein DUF1129 PF06570.11 OAI95786.1 - 4.9 6.6 8.3 0.56 9.7 1.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Chorismate_synt PF01264.21 OAI95788.1 - 4.9e-128 426.4 0.1 5.5e-128 426.3 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Tim54 PF11711.8 OAI95802.1 - 0.014 14.2 1.7 0.017 13.9 1.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cwf_Cwc_15 PF04889.12 OAI95802.1 - 0.018 14.8 14.2 0.025 14.3 14.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SLC12 PF03522.15 OAI95802.1 - 0.02 14.0 5.0 0.02 13.9 5.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 OAI95802.1 - 0.049 12.1 9.8 0.051 12.1 9.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 SPX PF03105.19 OAI95802.1 - 0.071 13.0 16.6 0.076 12.9 16.6 1.1 1 0 0 1 1 1 0 SPX domain HNF-1_N PF04814.13 OAI95802.1 - 0.12 13.0 8.0 0.15 12.7 8.0 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pox_Ag35 PF03286.14 OAI95802.1 - 0.13 12.1 14.0 0.17 11.7 14.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 OAI95802.1 - 0.24 10.1 7.1 0.25 10.1 7.1 1.1 1 0 0 1 1 1 0 Presenilin Ustilago_mating PF05722.12 OAI95802.1 - 0.28 10.7 12.0 0.36 10.3 12.0 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein NPR3 PF03666.13 OAI95802.1 - 0.31 9.8 13.0 0.35 9.6 13.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAGA-Tad1 PF12767.7 OAI95802.1 - 0.4 10.4 9.1 0.45 10.2 9.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Macoilin PF09726.9 OAI95802.1 - 0.51 8.8 11.5 0.58 8.7 11.5 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 OAI95802.1 - 1.1 8.0 15.0 1.2 7.9 15.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4551 PF15087.6 OAI95802.1 - 2.5 6.8 9.0 3.2 6.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FancD2 PF14631.6 OAI95802.1 - 2.7 5.2 6.2 3 5.1 6.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease AC_N PF16214.5 OAI95802.1 - 2.8 7.0 11.9 3.3 6.7 11.9 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RR_TM4-6 PF06459.12 OAI95802.1 - 5 6.9 8.9 6.3 6.5 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 OAI95802.1 - 8.9 4.9 10.4 9.5 4.8 10.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LysR_substrate PF03466.20 OAI95811.1 - 6.4e-49 166.2 1.9 6.4e-49 166.2 1.9 1.4 1 1 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 OAI95811.1 - 1.1e-20 73.4 3.1 3.8e-20 71.6 3.1 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 OAI95811.1 - 6.7e-05 22.1 0.0 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 1 PBP superfamily domain MarR_2 PF12802.7 OAI95811.1 - 0.00028 20.7 0.6 0.0012 18.7 0.6 2.1 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 OAI95811.1 - 0.00051 20.0 0.8 0.0051 16.9 0.4 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_30 PF13556.6 OAI95811.1 - 0.00093 19.0 0.3 0.0021 17.8 0.3 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR PF01047.22 OAI95811.1 - 0.0017 18.3 0.2 0.048 13.6 0.1 2.7 2 0 0 2 2 2 1 MarR family DUF4567 PF15131.6 OAI95811.1 - 0.0079 16.2 0.1 0.03 14.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4567) HTH_5 PF01022.20 OAI95811.1 - 0.0097 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 OAI95811.1 - 0.022 14.3 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OAI95811.1 - 0.077 12.8 3.0 0.13 12.1 0.2 2.7 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 OAI95811.1 - 0.083 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Cellulase PF00150.18 OAI95828.1 - 0.08 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF417 PF04224.12 OAI95830.1 - 2e-16 60.1 6.5 6.4e-15 55.1 2.6 2.0 1 1 1 2 2 2 2 Protein of unknown function, DUF417 Resolvase PF00239.21 OAI95831.1 - 8.2e-35 120.1 0.0 9e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain DsrH PF04077.12 OAI95831.1 - 0.063 13.4 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 DsrH like protein RVT_2 PF07727.14 OAI95835.1 - 3.1e-35 122.0 0.0 4.4e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC2_membrane PF01061.24 OAI95836.1 - 1.1e-43 149.1 22.0 1.1e-43 149.1 22.0 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 OAI95836.1 - 1.2e-19 70.0 4.8 2.3e-19 69.1 0.0 2.7 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 OAI95836.1 - 0.00013 21.2 19.1 0.00013 21.2 19.1 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 OAI95836.1 - 0.011 15.0 5.0 0.019 14.3 5.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein rve PF00665.26 OAI95839.1 - 4.1e-13 49.5 0.0 6.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAI95839.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain GFA PF04828.14 OAI95841.1 - 1.3e-16 60.7 0.0 1.3e-16 60.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme SBP_bac_3 PF00497.20 OAI95850.1 - 1.1e-24 87.1 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PAS_4 PF08448.10 OAI95850.1 - 1.6e-20 73.4 0.1 5.3e-20 71.7 0.1 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAI95850.1 - 1.1e-07 32.1 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OAI95850.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OAI95850.1 - 0.0017 18.4 0.0 0.0054 16.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain NMT1 PF09084.11 OAI95850.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.5 2 0 0 2 2 2 0 NMT1/THI5 like DUF4149 PF13664.6 OAI95850.1 - 0.04 14.2 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) IPTL-CTERM PF18203.1 OAI95850.1 - 0.4 10.6 10.0 1.1 9.3 10.0 1.7 1 0 0 1 1 1 0 IPTL-CTERM motif RadC PF04002.15 OAI95855.1 - 1.6e-35 121.7 0.0 2.5e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 OAI95855.1 - 0.00036 20.3 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MarR_2 PF12802.7 OAI95855.1 - 0.00049 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 OAI95855.1 - 0.014 14.9 0.0 0.037 13.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 OAI95855.1 - 0.021 15.3 0.1 0.065 13.7 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain MarR PF01047.22 OAI95855.1 - 0.083 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 MarR family Asp_protease_2 PF13650.6 OAI95856.1 - 2.5e-05 24.8 0.2 5.9e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI95856.1 - 0.0065 17.0 0.0 0.017 15.7 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI95856.1 - 0.045 14.1 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease UPF0016 PF01169.19 OAI95859.1 - 0.95 9.8 6.9 0.11 12.9 2.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 rve PF00665.26 OAI95868.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 OAI95870.1 - 0.16 12.2 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Acyl_transf_1 PF00698.21 OAI95877.1 - 1e-58 199.4 0.2 1.5e-58 198.8 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain MaoC_dehydratas PF01575.19 OAI95877.1 - 1e-27 96.2 0.0 4e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain Prok_Ub PF14454.6 OAI95877.1 - 0.13 12.0 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Ubiquitin Pec_lyase_C PF00544.19 OAI95881.1 - 5e-63 212.5 4.6 7.2e-63 212.0 4.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAI95881.1 - 3.8e-06 26.8 20.9 3.9e-05 23.5 20.9 2.2 1 1 1 2 2 2 1 Right handed beta helix region UreE_N PF02814.15 OAI95889.1 - 0.081 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Resolvase PF00239.21 OAI95899.1 - 1.1e-12 48.3 0.1 1.2e-12 48.2 0.1 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain Phage_integrase PF00589.22 OAI95902.1 - 2.2e-05 24.3 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF3504 PF12012.8 OAI95902.1 - 0.23 11.4 0.0 0.28 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) OCD_Mu_crystall PF02423.15 OAI95903.1 - 9.8e-29 100.3 0.0 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAI95903.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAI95903.1 - 0.049 13.7 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DNA_pol_viral_C PF00336.18 OAI95905.1 - 0.0051 16.2 0.1 0.0085 15.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Integrase_H2C2 PF17921.1 OAI95908.1 - 3.9e-20 71.7 0.7 6.9e-20 70.9 0.7 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI95908.1 - 3.8e-08 33.5 0.0 8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAI95908.1 - 0.13 12.5 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Thioredoxin_4 PF13462.6 OAI95919.1 - 7.9e-22 78.2 0.0 1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OAI95919.1 - 1.8e-16 60.5 1.1 2.3e-14 53.6 1.1 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 OAI95919.1 - 1.4e-06 28.7 0.0 3.4e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OAI95919.1 - 0.00024 21.1 0.0 0.24 11.5 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin domain Thioredoxin PF00085.20 OAI95919.1 - 0.0019 18.1 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OAI95919.1 - 0.024 14.6 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family Redoxin PF08534.10 OAI95919.1 - 0.063 13.0 0.1 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Redoxin DUF2240 PF09999.9 OAI95919.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) GutM PF06923.11 OAI95919.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) TFIIF_alpha PF05793.12 OAI95919.1 - 0.17 10.4 0.1 0.22 10.1 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Thioredoxin_8 PF13905.6 OAI95919.1 - 0.18 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like S4_2 PF13275.6 OAI95922.1 - 0.051 13.4 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 S4 domain DUF417 PF04224.12 OAI95928.1 - 5.2e-17 62.0 0.8 5.8e-17 61.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF417 MarR_2 PF12802.7 OAI95929.1 - 1.6e-10 40.7 3.7 1.7e-10 40.6 0.1 2.4 3 0 0 3 3 3 1 MarR family MarR PF01047.22 OAI95929.1 - 4.9e-08 32.8 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 OAI95929.1 - 3.7e-07 30.5 0.1 1.3e-06 28.8 0.1 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain FtsK_gamma PF09397.10 OAI95929.1 - 0.00095 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_29 PF13551.6 OAI95929.1 - 0.033 14.2 0.1 0.066 13.3 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 OAI95929.1 - 0.041 13.5 0.3 0.16 11.6 0.0 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 OAI95929.1 - 0.053 13.3 1.5 0.3 10.9 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain TrmB PF01978.19 OAI95929.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 OAI95929.1 - 0.097 13.3 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal PadR PF03551.14 OAI95929.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family p450 PF00067.22 OAI95934.1 - 1.9e-35 122.6 0.0 2.4e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TIR_3 PF18567.1 OAI95939.1 - 0.13 12.3 0.1 5.1 7.1 0.0 2.1 1 1 1 2 2 2 0 Toll/interleukin-1 receptor domain Rtf2 PF04641.12 OAI95945.1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Retrotrans_gag PF03732.17 OAI95951.1 - 0.14 12.4 0.1 0.43 10.9 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein PMC2NT PF08066.12 OAI95951.1 - 0.53 11.0 2.2 0.64 10.7 0.8 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Autotransporter PF03797.19 OAI95956.1 - 4.5e-40 137.9 10.7 8.9e-40 136.9 10.7 1.5 1 0 0 1 1 1 1 Autotransporter beta-domain MYCBPAP PF14646.6 OAI95958.1 - 0.097 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family DUF3509 PF12021.8 OAI95958.1 - 0.13 12.0 0.1 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) DDE_Tnp_Tn3 PF01526.17 OAI95962.1 - 5.1e-127 423.9 0.0 5.7e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain PPIP5K2_N PF18086.1 OAI95964.1 - 0.077 13.2 0.0 0.93 9.7 0.0 2.1 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain rve PF00665.26 OAI95973.1 - 7.3e-10 39.1 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAI95973.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain GntR PF00392.21 OAI95973.1 - 0.1 12.3 0.1 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family PID PF00640.23 OAI95976.1 - 0.051 13.6 0.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) TauE PF01925.19 OAI95981.1 - 2.5e-13 50.2 9.2 2.7e-13 50.1 9.2 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE YtxH PF12732.7 OAI95981.1 - 1.2 9.7 2.9 2.4 8.8 2.9 1.5 1 0 0 1 1 1 0 YtxH-like protein Thioredoxin_2 PF13098.6 OAI95982.1 - 8.5e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 OAI95982.1 - 4.1e-07 30.3 0.0 2.4e-06 27.8 0.0 2.0 1 1 0 2 2 2 1 Thioredoxin DSBA PF01323.20 OAI95982.1 - 0.00058 19.7 0.5 0.12 12.1 0.3 2.6 2 1 0 2 2 2 2 DSBA-like thioredoxin domain DsbC_N PF10411.9 OAI95982.1 - 0.0095 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_5 PF13743.6 OAI95982.1 - 0.16 11.6 0.0 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin MCPsignal PF00015.21 OAI95987.1 - 6.9e-18 65.0 1.5 9.6e-18 64.6 1.5 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ArdA PF07275.11 OAI95987.1 - 0.0077 16.8 0.0 0.0097 16.5 0.0 1.2 1 0 0 1 1 1 1 Antirestriction protein (ArdA) DUF3486 PF11985.8 OAI95987.1 - 0.073 13.5 2.5 0.28 11.6 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3486) EamA PF00892.20 OAI95988.1 - 2e-14 53.9 6.2 2e-14 53.9 6.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 OAI95988.1 - 9.9e-05 22.0 1.4 0.00015 21.4 1.4 1.2 1 0 0 1 1 1 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 OAI95988.1 - 0.043 13.0 1.3 0.068 12.3 1.3 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter YiaAB PF05360.14 OAI95988.1 - 0.072 13.3 0.4 0.072 13.3 0.4 3.5 4 0 0 4 4 4 0 yiaA/B two helix domain RseC_MucC PF04246.12 OAI95988.1 - 7.7 6.5 9.2 1 9.3 3.5 2.2 1 1 2 3 3 3 0 Positive regulator of sigma(E), RseC/MucC SLC12 PF03522.15 OAI95993.1 - 0.15 11.0 1.3 0.24 10.4 1.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SWIRM-assoc_2 PF16496.5 OAI95993.1 - 0.25 10.2 12.7 0.14 11.0 9.0 1.9 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal RAP1 PF07218.11 OAI95993.1 - 0.37 9.0 6.0 0.45 8.7 6.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 OAI95993.1 - 4 5.9 9.3 4.7 5.6 9.3 1.3 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 OAI95993.1 - 5.8 5.3 8.5 7.9 4.8 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 NPR3 PF03666.13 OAI95993.1 - 6.2 5.5 11.4 9.7 4.9 11.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spt5-NGN PF03439.13 OAI96005.1 - 1.6e-18 66.4 0.0 3.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 OAI96005.1 - 2.3e-15 57.3 5.4 2.3e-15 57.3 5.4 3.6 4 0 0 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 OAI96005.1 - 0.018 15.0 11.9 0.14 12.2 0.6 3.7 3 0 0 3 3 3 0 KOW motif DUF2457 PF10446.9 OAI96005.1 - 3 6.9 19.6 4.3 6.4 19.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) His_Phos_1 PF00300.22 OAI96016.1 - 2.4e-06 27.4 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps16_N PF04841.13 OAI96020.1 - 0.00024 20.0 0.0 0.00026 19.9 0.0 1.0 1 0 0 1 1 1 1 Vps16, N-terminal region HSBP1 PF06825.12 OAI96021.1 - 1.1e-14 54.0 0.4 1.4e-14 53.6 0.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 rRNA_proc-arch PF13234.6 OAI96022.1 - 2.9e-13 50.4 0.3 3.9e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 OAI96022.1 - 8e-07 29.4 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 OAI96022.1 - 0.044 12.9 1.7 0.086 11.9 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) Transposase_20 PF02371.16 OAI96024.1 - 1e-23 83.5 0.1 2.5e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 OAI96024.1 - 1.6e-17 63.8 0.0 5.9e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 Transposase GIT_CC PF16559.5 OAI96024.1 - 0.028 14.3 0.2 0.052 13.4 0.2 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSCPD PF12637.7 OAI96024.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 TSCPD domain FHA PF00498.26 OAI96027.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 FHA domain Myc_N PF01056.18 OAI96029.1 - 0.017 15.1 1.3 0.017 15.1 1.3 1.7 2 0 0 2 2 2 0 Myc amino-terminal region ORC6 PF05460.13 OAI96029.1 - 0.89 8.8 3.4 1.4 8.1 3.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Retrotrans_gag PF03732.17 OAI96032.1 - 3.3e-05 24.1 0.1 9.5e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein UPF0149 PF03695.13 OAI96039.1 - 2.8e-30 105.9 2.0 3.2e-30 105.7 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) SEC-C PF02810.15 OAI96039.1 - 2.6e-10 40.0 6.2 4e-10 39.4 6.2 1.3 1 0 0 1 1 1 1 SEC-C motif AlbA_2 PF04326.14 OAI96040.1 - 1.8e-11 44.4 0.0 6.5e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Putative DNA-binding domain LysR_substrate PF03466.20 OAI96043.1 - 4.7e-08 32.7 0.0 5.3e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain LysR_substrate PF03466.20 OAI96044.1 - 3.2e-23 82.2 5.0 6.2e-23 81.3 5.0 1.4 1 1 0 1 1 1 1 LysR substrate binding domain BTP PF05232.12 OAI96050.1 - 0.018 15.1 1.6 0.027 14.5 1.6 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Isochorismatase PF00857.20 OAI96052.1 - 1.2e-32 113.5 0.3 1.6e-32 113.1 0.3 1.1 1 0 0 1 1 1 1 Isochorismatase family COX3 PF00510.18 OAI96054.1 - 2.4e-20 73.5 8.5 3.1e-20 73.1 8.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Vma12 PF11712.8 OAI96054.1 - 2.3 8.3 9.7 0.6 10.2 3.4 2.5 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Voltage_CLC PF00654.20 OAI96056.1 - 2.2e-52 178.5 25.3 2.2e-52 178.5 25.3 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel HTH_Tnp_1 PF01527.20 OAI96057.1 - 4.2e-19 68.6 0.0 4.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 OAI96057.1 - 3.5e-05 23.1 0.0 0.00012 21.4 0.0 1.8 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 OAI96057.1 - 8.3e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 OAI96057.1 - 0.0001 22.0 0.1 0.00024 20.8 0.1 1.7 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 OAI96057.1 - 0.00038 20.4 0.4 0.00076 19.5 0.1 1.8 2 1 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 OAI96057.1 - 0.0084 16.1 0.0 0.0095 16.0 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.15 OAI96057.1 - 0.013 15.6 0.1 0.048 13.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Phage_CI_repr PF07022.13 OAI96057.1 - 0.032 14.3 0.0 2.7 8.2 0.0 2.4 2 1 1 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 OAI96057.1 - 0.038 14.1 0.1 0.11 12.6 0.0 1.7 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase BcrAD_BadFG PF01869.20 OAI96062.1 - 2.2e-23 83.1 1.4 2.3e-23 83.1 1.4 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 OAI96062.1 - 0.066 12.8 0.0 0.85 9.1 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain HGTP_anticodon PF03129.20 OAI96069.1 - 0.083 13.0 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain fn3_5 PF06280.12 OAI96071.1 - 0.12 13.0 0.2 0.29 11.8 0.1 1.6 2 0 0 2 2 2 0 Fn3-like domain HupE_UreJ_2 PF13795.6 OAI96072.1 - 3.8e-51 172.8 8.1 4.9e-51 172.4 8.1 1.1 1 0 0 1 1 1 1 HupE / UreJ protein PIF1 PF05970.14 OAI96076.1 - 0.0071 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Torsin PF06309.11 OAI96076.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin UPF0524 PF15823.5 OAI96078.1 - 0.13 11.7 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 SARAF PF06682.12 OAI96078.1 - 2.5 7.7 14.3 2.9 7.4 14.3 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4158 PF13700.6 OAI96088.1 - 1.1e-41 142.5 7.9 1.2e-41 142.3 2.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4158) Ferritin_2 PF13668.6 OAI96105.1 - 2.9e-06 27.5 0.3 4.6e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF3449 PF11931.8 OAI96110.1 - 2.8e-64 216.3 1.1 3.4e-64 216.0 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) PMSR PF01625.21 OAI96116.1 - 0.00027 21.1 0.1 0.085 13.0 0.0 2.3 1 1 1 2 2 2 2 Peptide methionine sulfoxide reductase Oxidored_molyb PF00174.19 OAI96117.1 - 1.1e-21 77.2 0.3 4.5e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Oxidoreductase molybdopterin binding domain ATP-grasp_4 PF13535.6 OAI96125.1 - 1.3e-08 34.6 0.0 0.0038 16.9 0.0 3.2 3 0 0 3 3 3 3 ATP-grasp domain ATP-grasp_3 PF02655.14 OAI96125.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_12 PF13424.6 OAI96130.1 - 1.6e-08 34.7 15.1 0.0088 16.3 0.3 5.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAI96130.1 - 4.2e-06 26.5 4.1 3.6 7.6 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAI96130.1 - 0.3 11.8 6.6 47 5.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4945 PF16303.5 OAI96132.1 - 0.22 11.4 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) adh_short_C2 PF13561.6 OAI96138.1 - 4.7e-37 127.8 0.0 5.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAI96138.1 - 6.6e-21 74.7 0.0 8e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAI96138.1 - 0.0023 17.9 0.1 0.0029 17.5 0.1 1.2 1 0 0 1 1 1 1 KR domain DDOST_48kD PF03345.14 OAI96139.1 - 2.8e-28 98.9 0.0 3.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 OAI96139.1 - 0.2 10.0 0.0 0.24 9.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Tho1_MOS11_C PF18592.1 OAI96142.1 - 0.35 10.7 1.4 5 7.0 0.1 2.4 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain TonB_dep_Rec PF00593.24 OAI96144.1 - 1.7e-15 57.9 6.1 1.9e-15 57.7 6.1 1.0 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 OAI96144.1 - 0.00018 20.6 1.1 0.00023 20.3 1.1 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family OEP PF02321.18 OAI96144.1 - 0.047 13.5 0.3 0.073 12.9 0.3 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein AAA PF00004.29 OAI96147.1 - 1e-15 58.3 0.1 4.8e-15 56.1 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAI96147.1 - 7.1e-05 23.2 0.3 0.00038 20.9 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAI96147.1 - 0.008 16.2 0.1 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2442 PF10387.9 OAI96147.1 - 0.0089 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2442) AAA_22 PF13401.6 OAI96147.1 - 0.014 15.7 0.8 0.09 13.0 0.5 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 OAI96147.1 - 0.018 15.2 0.0 0.023 14.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAI96147.1 - 0.029 14.1 0.1 0.077 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAI96147.1 - 0.083 13.1 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 OAI96147.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 OAI96147.1 - 0.45 10.8 1.4 0.9 9.9 1.1 1.8 1 1 0 1 1 1 0 AAA domain Lambda_CIII PF02061.16 OAI96151.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Lambda Phage CIII Thr_dehydrat_C PF00585.18 OAI96154.1 - 1.2e-14 53.8 0.1 1.3e-13 50.5 0.0 2.1 1 1 1 2 2 2 1 C-terminal regulatory domain of Threonine dehydratase Integrase_H2C2 PF17921.1 OAI96157.1 - 9.6e-15 54.4 0.3 1.9e-14 53.5 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI96157.1 - 4.3e-14 52.7 0.0 2e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain WD40 PF00400.32 OAI96160.1 - 9.8e-14 51.5 5.8 0.00016 22.4 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 OAI96160.1 - 1.1e-06 27.6 0.4 0.00049 18.9 0.1 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 EzrA PF06160.12 OAI96160.1 - 0.26 9.4 1.2 0.35 9.0 1.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NAD_binding_5 PF07994.12 OAI96168.1 - 2.9e-25 89.3 0.0 3.4e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Cecropin PF00272.19 OAI96175.1 - 0.021 14.5 0.1 0.063 13.0 0.1 1.8 1 0 0 1 1 1 0 Cecropin family LPD5 PF18799.1 OAI96175.1 - 0.035 14.5 0.6 0.035 14.5 0.6 3.2 2 2 1 3 3 3 0 Large polyvalent protein-associated domain 5 NPIP PF06409.11 OAI96175.1 - 0.07 12.2 1.2 0.16 11.0 1.0 1.7 1 1 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) YiiD_C PF09500.10 OAI96175.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.0 2 1 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF948 PF06103.11 OAI96175.1 - 0.29 11.4 17.8 2.2 8.6 0.9 4.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PMEI PF04043.15 OAI96175.1 - 0.36 11.2 6.8 6.3 7.1 1.7 2.6 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF720 PF05302.11 OAI96175.1 - 0.62 9.9 10.0 0.038 13.8 2.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF720) Fib_alpha PF08702.10 OAI96175.1 - 0.67 10.1 25.3 1 9.5 0.5 3.7 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF2431 PF10354.9 OAI96175.1 - 0.96 9.7 2.8 1.6 9.0 0.5 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF2431) DUF4041 PF13250.6 OAI96175.1 - 1.1 9.2 7.2 6.9 6.6 0.2 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4041) DUF4795 PF16043.5 OAI96175.1 - 1.4 8.5 30.9 0.14 11.7 9.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF648 PF04890.13 OAI96175.1 - 1.5 8.5 6.7 0.36 10.5 2.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF648) NPV_P10 PF05531.12 OAI96175.1 - 1.5 9.3 14.0 3.7 8.1 1.3 4.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ZapD PF07072.11 OAI96175.1 - 2.3 7.9 17.4 0.052 13.3 2.5 3.5 2 2 0 2 2 2 0 Cell division protein DciA PF05258.12 OAI96175.1 - 2.7 8.4 6.1 27 5.2 0.0 3.7 4 0 0 4 4 4 0 Dna[CI] antecedent, DciA Rab5-bind PF09311.11 OAI96175.1 - 4.4 6.6 35.9 0.31 10.4 12.1 3.9 2 2 2 4 4 4 0 Rabaptin-like protein DUF4407 PF14362.6 OAI96175.1 - 4.4 6.6 28.9 0.045 13.1 9.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OAI96175.1 - 4.7 6.0 39.4 0.12 11.3 11.6 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein SPG4 PF17325.2 OAI96175.1 - 7.1 7.8 12.6 0.22 12.6 3.1 2.6 2 1 0 2 2 2 0 Stationary phase protein 4 Bacillus_HBL PF05791.11 OAI96175.1 - 7.6 6.3 12.1 0.97 9.2 0.2 3.4 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Cytochrom_C PF00034.21 OAI96178.1 - 0.088 14.0 0.0 0.092 13.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c COX1 PF00115.20 OAI96179.1 - 4.6e-147 490.4 61.9 5.2e-147 490.2 61.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I FixH PF05751.11 OAI96179.1 - 0.09 12.8 0.5 0.09 12.8 0.5 2.8 3 0 0 3 3 3 0 FixH HAMP PF00672.25 OAI96181.1 - 5.8e-10 39.4 0.1 1.5e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 HAMP domain TarH PF02203.15 OAI96181.1 - 0.00033 20.6 3.8 0.00058 19.8 3.8 1.5 1 0 0 1 1 1 1 Tar ligand binding domain homologue IKBKB_SDD PF18397.1 OAI96181.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Asn_synthase PF00733.21 OAI96185.1 - 7.6e-10 39.0 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase zf-C2H2 PF00096.26 OAI96188.1 - 6.8e-05 23.1 0.1 0.00014 22.1 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAI96188.1 - 0.0097 16.7 0.2 0.019 15.8 0.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger Retrotrans_gag PF03732.17 OAI96193.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein CCDC106 PF15794.5 OAI96193.1 - 0.096 12.4 0.7 0.17 11.5 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Shugoshin_N PF07558.11 OAI96193.1 - 0.1 12.5 1.2 15 5.6 0.1 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF2205 PF10224.9 OAI96193.1 - 0.15 12.1 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF1491 PF07372.12 OAI96197.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) CAP_N PF01213.19 OAI96201.1 - 3 7.3 10.5 3.3 7.1 10.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Helicase_C_4 PF13871.6 OAI96205.1 - 3.5e-41 141.7 0.0 8e-41 140.5 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain on Strawberry notch homologue CFEM PF05730.11 OAI96208.1 - 1.1e-08 35.0 11.5 1.9e-08 34.2 11.5 1.4 1 0 0 1 1 1 1 CFEM domain Hydrolase_like PF13242.6 OAI96209.1 - 2.8e-13 49.7 0.0 3.2e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAI96209.1 - 0.0089 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OAI96209.1 - 0.0093 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase MCM_bind PF09739.9 OAI96214.1 - 0.006 15.1 0.3 0.0065 15.0 0.3 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Catalase PF00199.19 OAI96217.1 - 5.6e-63 213.3 0.2 6.5e-63 213.1 0.2 1.0 1 0 0 1 1 1 1 Catalase DUF5053 PF16476.5 OAI96217.1 - 0.034 13.8 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Med3 PF11593.8 OAI96222.1 - 0.0009 18.5 13.9 0.0013 18.0 13.9 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF3435 PF11917.8 OAI96222.1 - 0.019 13.9 0.1 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4195 PF13836.6 OAI96222.1 - 0.037 14.1 6.8 0.071 13.2 6.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4195) TFIIA PF03153.13 OAI96222.1 - 0.29 11.1 7.4 0.34 10.8 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NuDC PF16273.5 OAI96224.1 - 0.14 12.7 0.4 0.2 12.2 0.4 1.1 1 0 0 1 1 1 0 Nuclear distribution C domain RRM_1 PF00076.22 OAI96228.1 - 2.3e-06 27.3 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_Tnp_4 PF13359.6 OAI96232.1 - 6.7e-12 45.4 0.0 9.1e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2608 PF11019.8 OAI96235.1 - 0.016 14.7 0.0 0.019 14.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Abhydro_lipase PF04083.16 OAI96235.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region FMO-like PF00743.19 OAI96237.1 - 9.3e-14 50.7 0.0 1.3e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAI96237.1 - 6.3e-13 48.6 0.0 8.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAI96237.1 - 3.3e-12 46.2 0.0 5.8e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAI96237.1 - 1.7e-10 41.0 0.0 2e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAI96237.1 - 2e-08 33.9 0.0 7.9e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAI96237.1 - 4.3e-07 30.1 0.0 0.00039 20.4 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAI96237.1 - 1.7e-06 27.9 0.0 0.0095 15.5 0.0 3.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAI96237.1 - 9.3e-05 21.3 0.0 0.27 9.9 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 OAI96237.1 - 0.00048 20.6 0.0 0.75 10.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAI96237.1 - 0.04 13.1 0.0 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 OAI96237.1 - 0.086 12.9 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAI96237.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DSHCT PF08148.12 OAI96242.1 - 1.2e-24 86.9 0.5 2.9e-24 85.6 0.3 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OAI96242.1 - 1.2e-11 45.1 0.1 1.7e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Dynamitin PF04912.14 OAI96242.1 - 0.048 13.0 0.2 0.072 12.4 0.2 1.2 1 0 0 1 1 1 0 Dynamitin Pkinase PF00069.25 OAI96246.1 - 9.7e-26 90.7 0.0 1.4e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI96246.1 - 2.2e-10 40.3 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S4e PF00900.20 OAI96246.1 - 0.062 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal family S4e Kinase-like PF14531.6 OAI96246.1 - 0.17 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FliD_N PF02465.18 OAI96248.1 - 0.0056 17.3 0.2 0.014 16.1 0.2 1.6 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus P66_CC PF16563.5 OAI96248.1 - 0.2 11.3 1.7 0.38 10.4 1.7 1.5 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 AbiEii PF08843.11 OAI96257.1 - 0.0034 17.4 0.3 0.02 14.9 0.3 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DNA_pol_viral_C PF00336.18 OAI96259.1 - 0.012 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RT_RNaseH_2 PF17919.1 OAI96268.1 - 1.6e-32 111.5 0.0 3.6e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI96268.1 - 5.1e-30 103.9 0.0 1e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4932 PF16286.5 OAI96274.1 - 1.4e-44 152.8 0.0 1.6e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4932) TAF4 PF05236.14 OAI96278.1 - 0.11 12.2 1.8 0.26 11.0 1.8 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IATP PF04568.12 OAI96278.1 - 7.4 7.1 6.8 5.2 7.6 4.4 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP NAD_binding_10 PF13460.6 OAI96280.1 - 0.16 11.8 0.0 2.6 7.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Barstar PF01337.18 OAI96283.1 - 0.13 12.3 0.2 0.38 10.8 0.1 1.9 2 0 0 2 2 2 0 Barstar (barnase inhibitor) DDE_1 PF03184.19 OAI96286.1 - 2.8e-35 121.5 0.1 7.8e-35 120.1 0.1 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAI96286.1 - 9.2e-15 54.4 0.2 2.6e-14 53.0 0.2 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PAS_6 PF08348.11 OAI96286.1 - 0.037 13.9 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 YheO-like PAS domain DDE_3 PF13358.6 OAI96286.1 - 0.045 13.5 0.1 0.53 10.0 0.0 2.5 3 0 0 3 3 3 0 DDE superfamily endonuclease RraA-like PF03737.15 OAI96289.1 - 1.6e-36 125.7 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA DUF3484 PF11983.8 OAI96289.1 - 0.2 12.8 5.0 0.45 11.7 5.0 1.5 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch DEC-1_N PF04625.13 OAI96289.1 - 1.3 8.0 10.1 1.8 7.5 10.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AMP-binding PF00501.28 OAI96290.1 - 1e-06 27.6 0.0 1.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAI96290.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Dimer_Tnp_hAT PF05699.14 OAI96301.1 - 1.1e-08 34.8 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FadA PF09403.10 OAI96304.1 - 0.056 13.9 1.0 0.15 12.6 1.0 1.7 1 0 0 1 1 1 0 Adhesion protein FadA RVT_1 PF00078.27 OAI96307.1 - 3.3e-24 85.7 0.0 5.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAI96307.1 - 0.00046 20.8 0.7 0.0014 19.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease dUTPase PF00692.19 OAI96307.1 - 0.0026 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 dUTPase gag-asp_proteas PF13975.6 OAI96307.1 - 0.097 13.2 0.0 0.33 11.6 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SF3A2 PF16835.5 OAI96308.1 - 8.2e-29 99.8 0.0 1e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAI96308.1 - 1.5e-06 28.4 0.7 3.2e-06 27.3 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Linocin_M18 PF04454.12 OAI96308.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase PAS PF00989.25 OAI96310.1 - 6.9e-21 74.4 0.2 1e-09 38.4 0.0 3.2 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 OAI96310.1 - 1.9e-14 53.7 0.3 7.7e-09 35.7 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 OAI96310.1 - 9.1e-14 51.1 0.2 1.8e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 OAI96310.1 - 2.1e-09 37.6 0.0 0.0015 18.7 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 OAI96310.1 - 3.3e-08 33.8 3.1 0.0015 18.8 0.2 3.2 3 0 0 3 3 3 2 PAS fold DUF1418 PF07214.12 OAI96310.1 - 0.044 13.6 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DNA_methylase PF00145.17 OAI96312.1 - 1.8e-26 93.3 0.0 2.7e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RE_EcoO109I PF14511.6 OAI96313.1 - 0.0043 16.7 0.0 0.0097 15.5 0.0 1.6 1 1 0 1 1 1 1 Type II restriction endonuclease EcoO109I CRAL_TRIO_N PF03765.15 OAI96328.1 - 4e-13 49.3 1.2 8.1e-13 48.3 1.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TelA PF05816.11 OAI96328.1 - 0.0045 16.1 0.2 0.008 15.3 0.1 1.4 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) DNA_pol_A_exoN PF18305.1 OAI96328.1 - 0.021 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain p450 PF00067.22 OAI96332.1 - 2.8e-10 39.6 0.0 3.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_19 PF14559.6 OAI96339.1 - 2.7e-07 31.0 20.9 0.0054 17.2 0.2 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAI96339.1 - 1.1e-05 26.0 19.0 0.73 10.5 7.5 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 OAI96339.1 - 0.00044 20.5 6.1 0.24 11.7 0.1 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAI96339.1 - 0.0073 17.0 42.9 0.2 12.6 0.1 8.2 3 1 6 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAI96339.1 - 0.06 13.5 6.1 25 5.3 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fur_reg_FbpA PF13076.6 OAI96339.1 - 0.41 10.4 2.0 0.98 9.2 0.6 2.3 2 0 0 2 2 2 0 Fur-regulated basic protein A TPR_7 PF13176.6 OAI96339.1 - 0.79 9.9 7.6 3.9 7.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4328 PF14219.6 OAI96345.1 - 0.0029 17.2 0.4 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) RVT_2 PF07727.14 OAI96357.1 - 2.2e-35 122.5 0.0 3e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI96357.1 - 0.035 13.9 3.2 0.075 12.8 2.7 1.8 1 1 0 1 1 1 0 Reverse transcriptase-like Myb_DNA-bind_3 PF12776.7 OAI96358.1 - 0.00096 20.1 0.4 0.0019 19.1 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4692 PF15763.5 OAI96358.1 - 0.037 14.5 0.5 0.044 14.3 0.5 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Phage_integrase PF00589.22 OAI96364.1 - 5e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Thi4 PF01946.17 OAI96370.1 - 0.063 12.5 1.3 3.9 6.7 1.3 2.2 1 1 0 1 1 1 0 Thi4 family Integrase_H2C2 PF17921.1 OAI96374.1 - 1.5e-13 50.6 0.4 3.8e-13 49.3 0.4 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAI96374.1 - 1.8e-13 50.7 0.0 9.1e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAI96374.1 - 4.2e-12 46.3 0.0 8.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAI96374.1 - 2.1e-07 30.9 0.0 1e-06 28.7 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 OAI96378.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Spem1 PF15670.5 OAI96380.1 - 0.029 14.0 0.8 0.041 13.5 0.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Rrn6 PF10214.9 OAI96380.1 - 1.4 7.4 10.8 1.9 6.9 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor OrgA_MxiK PF09482.10 OAI96383.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Acyl-CoA_ox_N PF14749.6 OAI96388.1 - 1.1e-15 58.3 0.0 1.7e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAI96388.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain PTPRCAP PF15713.5 OAI96391.1 - 0.0014 18.9 0.9 0.0023 18.2 0.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Uso1_p115_C PF04871.13 OAI96391.1 - 0.0025 18.2 4.8 3.3 8.1 0.0 2.2 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-B_dimeris PF09026.10 OAI96391.1 - 0.0033 17.8 3.8 0.0049 17.2 3.8 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF4611 PF15387.6 OAI96391.1 - 0.0034 17.6 2.6 0.1 12.8 1.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 OAI96391.1 - 0.0053 14.9 1.0 0.0073 14.5 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase phi FAM176 PF14851.6 OAI96391.1 - 0.079 12.6 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 OAI96391.1 - 2.1 6.3 7.1 3.6 5.6 7.1 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 OAI96391.1 - 4.3 6.6 7.6 5.9 6.1 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein Kei1 PF08552.11 OAI96392.1 - 0.35 10.7 0.2 0.39 10.6 0.2 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NPR3 PF03666.13 OAI96392.1 - 1.7 7.3 8.5 1.8 7.2 8.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 OAI96392.1 - 5.5 6.3 13.4 5.7 6.3 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Apolipoprotein PF01442.18 OAI96398.1 - 0.0002 21.3 0.7 0.00031 20.7 0.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAI96398.1 - 0.055 14.1 0.1 0.055 14.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Asp PF00026.23 OAI96402.1 - 9.8e-14 51.5 0.0 1.2e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Phage_integrase PF00589.22 OAI96404.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family UTP25 PF06862.12 OAI96409.1 - 1.4e-32 113.2 0.0 1.8e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UTP25 PF06862.12 OAI96410.1 - 3.9e-17 62.2 0.0 7.5e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Phage_int_SAM_1 PF02899.17 OAI96414.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 OAI96417.1 - 0.073 13.5 0.9 0.19 12.1 0.9 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PIN_12 PF16289.5 OAI96417.1 - 0.71 10.3 5.3 0.14 12.6 0.7 2.1 2 0 0 2 2 2 0 PIN domain I_LWEQ PF01608.17 OAI96417.1 - 4.9 7.4 12.0 1.6 8.9 3.1 2.4 2 0 0 2 2 2 0 I/LWEQ domain Rx_N PF18052.1 OAI96417.1 - 9.9 6.5 9.0 5.6 7.3 3.2 2.7 2 1 0 2 2 2 0 Rx N-terminal domain Resolvase PF00239.21 OAI96420.1 - 6.4e-29 100.9 0.1 7.1e-29 100.8 0.1 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain LcrR PF09621.10 OAI96420.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.5 1 1 1 2 2 2 0 Type III secretion system regulator (LcrR) Retrotran_gag_2 PF14223.6 OAI96428.1 - 0.0026 17.4 0.4 0.0072 16.0 0.1 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type GRP PF07172.11 OAI96429.1 - 0.098 13.4 9.8 0.19 12.4 9.8 1.4 1 0 0 1 1 1 0 Glycine rich protein family zf-CCHC PF00098.23 OAI96429.1 - 0.47 10.6 10.9 0.45 10.7 8.7 2.1 2 0 0 2 2 2 0 Zinc knuckle DNA_pol_viral_C PF00336.18 OAI96430.1 - 0.025 14.0 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain GST_N_5 PF18485.1 OAI96433.1 - 0.15 12.5 0.1 0.33 11.3 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PP2C PF00481.21 OAI96437.1 - 6.2e-12 45.7 0.0 9.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C zf-CCHC PF00098.23 OAI96441.1 - 1.3e-05 25.0 0.6 2.1e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAI96441.1 - 0.00064 19.5 1.0 0.001 18.8 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle Yae1_N PF09811.9 OAI96441.1 - 0.019 14.7 1.8 0.041 13.6 1.8 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Sugarporin_N PF11471.8 OAI96441.1 - 0.093 12.7 0.7 0.21 11.5 0.3 1.7 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension SNARE_assoc PF09335.11 OAI96443.1 - 6.9e-22 78.2 5.3 6.9e-22 78.2 5.3 2.9 3 0 0 3 3 3 1 SNARE associated Golgi protein Pyr_redox_2 PF07992.14 OAI96443.1 - 5.3e-07 29.2 0.1 7.1e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAI96443.1 - 2e-05 24.1 0.5 2.8e-05 23.7 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAI96443.1 - 6.9e-05 22.6 0.1 9.7e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAI96443.1 - 0.0017 18.5 0.8 0.0033 17.6 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAI96443.1 - 0.0062 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAI96443.1 - 0.013 14.2 0.8 0.017 13.8 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OAI96443.1 - 0.016 14.3 2.1 0.023 13.8 1.8 1.4 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 OAI96443.1 - 0.023 13.6 0.1 0.029 13.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF5438 PF17506.2 OAI96443.1 - 0.04 14.2 1.6 0.046 14.0 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5438) GIDA PF01134.22 OAI96443.1 - 0.13 11.3 0.7 0.17 10.9 0.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 OAI96443.1 - 0.16 12.6 0.9 0.36 11.4 0.9 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF883 PF05957.13 OAI96443.1 - 0.18 12.4 1.0 5.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AlaDh_PNT_C PF01262.21 OAI96443.1 - 0.19 11.0 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PHD PF00628.29 OAI96446.1 - 0.01 15.7 0.2 0.01 15.7 0.2 2.6 3 0 0 3 3 3 0 PHD-finger Filaggrin PF03516.13 OAI96446.1 - 0.075 13.8 1.7 0.096 13.4 0.2 1.9 2 0 0 2 2 2 0 Filaggrin rve PF00665.26 OAI96453.1 - 1.2e-16 61.0 0.1 2.8e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI96453.1 - 4.7e-13 49.0 0.0 1.2e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAI96453.1 - 0.0033 17.2 0.0 0.008 15.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAI96453.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger MULE PF10551.9 OAI96456.1 - 1.3e-10 41.5 0.1 4.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAI96456.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Phage_integrase PF00589.22 OAI96459.1 - 2.5e-05 24.1 1.2 7.4e-05 22.6 0.0 2.2 3 0 0 3 3 3 1 Phage integrase family PHP PF02811.19 OAI96463.1 - 1.2e-09 38.7 0.6 2.3e-09 37.8 0.6 1.5 1 1 0 1 1 1 1 PHP domain RNA_pol_Rpb4 PF03874.16 OAI96468.1 - 4.9e-14 52.7 0.0 1.6e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 UPF0565 PF10561.9 OAI96474.1 - 0.013 14.7 0.4 0.013 14.7 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 GRP PF07172.11 OAI96474.1 - 8.7 7.1 24.9 0.54 11.0 0.2 3.2 2 1 0 3 3 3 0 Glycine rich protein family Rad60-SLD PF11976.8 OAI96477.1 - 0.0041 16.9 0.3 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ATG16 PF08614.11 OAI96481.1 - 0.028 14.6 1.1 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) RNase_H PF00075.24 OAI96484.1 - 1.3e-09 38.4 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 OAI96484.1 - 0.034 14.8 0.2 0.099 13.4 0.1 1.8 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_3 PF13456.6 OAI96484.1 - 0.037 13.8 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Asp PF00026.23 OAI96486.1 - 6.1e-16 58.7 7.3 4e-15 56.0 7.3 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAI96486.1 - 3.2e-05 24.3 3.1 0.00012 22.3 0.2 2.6 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAI96486.1 - 0.0026 18.4 1.9 0.0077 16.9 0.4 2.3 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI96486.1 - 0.0082 16.7 0.8 0.033 14.7 0.1 2.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease M PF02370.16 OAI96489.1 - 0.59 10.9 2.9 2.4 9.0 2.9 2.1 1 0 0 1 1 1 0 M protein repeat Haem_degrading PF03928.14 OAI96491.1 - 3.2e-20 72.4 0.0 3.5e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading GAF_2 PF13185.6 OAI96491.1 - 0.032 14.5 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 GAF domain Transthyretin PF00576.21 OAI96492.1 - 1.8e-36 125.2 0.0 2.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family bMG3 PF11974.8 OAI96492.1 - 0.00013 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 OAI96492.1 - 0.0096 15.9 1.3 0.15 12.1 0.3 2.7 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 OAI96492.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF824 PF05688.11 OAI96492.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DUF4280 PF14107.6 OAI96493.1 - 3.6e-22 79.2 0.0 4e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4280) Shugoshin_N PF07558.11 OAI96495.1 - 0.0096 15.8 0.7 5.4 7.0 0.0 2.9 3 0 0 3 3 3 2 Shugoshin N-terminal coiled-coil region Retrotrans_gag PF03732.17 OAI96495.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2205 PF10224.9 OAI96495.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF4692 PF15763.5 OAI96495.1 - 5.7 7.4 6.9 11 6.4 6.9 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SYF2 PF08231.12 OAI96497.1 - 0.2 12.0 9.1 0.48 10.8 4.1 2.3 1 1 1 2 2 2 0 SYF2 splicing factor Hydant_A_N PF05378.13 OAI96499.1 - 1.7e-60 203.8 0.6 2.3e-58 196.8 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 OAI96499.1 - 7.3e-26 91.1 0.7 4.4e-24 85.3 0.7 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Muskelin_N PF06588.11 OAI96503.1 - 6.8e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Muskelin N-terminus An_peroxidase PF03098.15 OAI96505.1 - 2.6e-19 69.2 0.0 1.5e-09 37.0 0.0 2.0 2 0 0 2 2 2 2 Animal haem peroxidase BRO1 PF03097.18 OAI96507.1 - 5.5e-05 22.2 0.0 7e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF659 PF04937.15 OAI96519.1 - 1.4e-05 25.0 0.0 3.7e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) ParBc PF02195.18 OAI96522.1 - 8.2e-15 54.9 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain SoPB_HTH PF18090.1 OAI96522.1 - 5.7e-14 52.0 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Centromere-binding protein HTH domain HTH_31 PF13560.6 OAI96522.1 - 0.00028 21.2 0.9 0.0028 17.9 0.2 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 OAI96522.1 - 0.02 14.9 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_31 PF13614.6 OAI96523.1 - 1.8e-15 57.3 0.1 2.9e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 OAI96523.1 - 0.0015 17.9 0.1 0.0021 17.4 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ ParA PF10609.9 OAI96523.1 - 0.038 13.4 0.4 0.079 12.4 0.2 1.6 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AA_permease_2 PF13520.6 OAI96540.1 - 2e-42 145.5 23.6 6.4e-42 143.9 23.6 1.6 1 1 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 OAI96542.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_10 PF13374.6 OAI96542.1 - 1.1 9.2 6.4 9.4 6.3 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.13 OAI96542.1 - 2.4 8.1 8.9 0.45 10.5 3.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PDEase_I_N PF08499.12 OAI96545.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal SGL PF08450.12 OAI96550.1 - 1.9e-35 122.6 0.1 2.3e-35 122.3 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAI96550.1 - 2e-07 30.7 1.0 0.079 13.0 0.0 3.6 3 0 0 3 3 3 2 NHL repeat Reg_prop PF07494.11 OAI96550.1 - 4.8e-05 23.1 1.6 0.31 11.4 0.1 3.0 2 1 0 2 2 2 2 Two component regulator propeller Str_synth PF03088.16 OAI96550.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Strictosidine synthase zf-nanos PF05741.13 OAI96550.1 - 0.049 13.9 0.1 0.085 13.1 0.1 1.4 1 0 0 1 1 1 0 Nanos RNA binding domain Arylesterase PF01731.20 OAI96550.1 - 0.21 11.8 0.0 0.64 10.3 0.0 1.8 2 0 0 2 2 2 0 Arylesterase SRP-alpha_N PF04086.13 OAI96553.1 - 1.9 8.3 21.4 2.4 8.0 21.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOBP PF15279.6 OAI96553.1 - 7.1 7.2 8.7 8.1 6.9 8.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Sulfatase PF00884.23 OAI96555.1 - 2.9e-34 118.9 0.0 3.2e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAI96555.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DNA_gyraseA_C PF03989.13 OAI96560.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller PAP2 PF01569.21 OAI96561.1 - 2e-13 50.3 3.5 7.2e-13 48.5 3.5 1.9 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 OAI96561.1 - 0.0016 17.8 7.2 0.004 16.5 1.2 2.2 2 0 0 2 2 2 2 UbiA prenyltransferase family UPF0542 PF15086.6 OAI96561.1 - 0.0088 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 YhhN PF07947.14 OAI96561.1 - 6.7 6.3 8.4 1.4 8.5 1.5 2.2 2 0 0 2 2 2 0 YhhN family HEAT_UF PF18817.1 OAI96562.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Repeat of uncharacterized protein PH0542 Histone PF00125.24 OAI96566.1 - 4.6e-13 49.7 0.5 5.1e-13 49.5 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RNA_pol_Rpb6 PF01192.22 OAI96566.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb6 DDE_Tnp_4 PF13359.6 OAI96570.1 - 4.6e-23 81.6 0.0 5.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAI96570.1 - 6.3e-05 22.7 0.0 8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Pyr_redox_2 PF07992.14 OAI96572.1 - 4.4e-30 104.9 1.4 5.5e-30 104.6 1.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAI96572.1 - 9.1e-11 41.6 1.0 2.1e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAI96572.1 - 1.1e-10 42.0 0.3 6.5e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAI96572.1 - 1.5e-05 25.2 1.0 0.096 13.0 0.0 3.0 3 0 0 3 3 3 2 TrkA-N domain K_oxygenase PF13434.6 OAI96572.1 - 4e-05 22.9 2.9 0.00015 21.0 0.2 2.8 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OAI96572.1 - 4.7e-05 23.8 3.9 0.0073 16.7 0.1 3.3 3 1 0 3 3 3 1 Putative NAD(P)-binding DAO PF01266.24 OAI96572.1 - 0.00065 19.4 7.5 0.41 10.2 0.2 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAI96572.1 - 0.0012 17.8 2.9 0.0063 15.4 0.1 2.4 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 OAI96572.1 - 0.0032 17.7 0.1 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAI96572.1 - 0.01 15.1 0.8 0.19 10.9 0.1 2.3 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 OAI96572.1 - 0.011 15.1 0.1 3 7.1 0.1 2.4 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 OAI96572.1 - 0.021 14.8 5.1 1.6 8.7 0.0 3.9 5 0 0 5 5 5 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAI96572.1 - 0.048 13.9 0.4 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAI96572.1 - 0.055 13.5 1.8 3.4 7.7 0.1 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAI96572.1 - 0.064 12.5 0.3 4.1 6.6 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 OAI96572.1 - 0.066 12.2 0.7 3.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OAI96572.1 - 0.089 11.5 3.0 3.3 6.3 0.1 3.5 2 1 1 4 4 4 0 HI0933-like protein PEMT PF04191.13 OAI96584.1 - 1.3e-35 122.0 5.3 1.3e-35 122.0 5.3 1.4 2 0 0 2 2 2 1 Phospholipid methyltransferase FG-GAP PF01839.23 OAI96586.1 - 0.014 15.6 1.7 0.021 14.9 1.7 1.3 1 0 0 1 1 1 0 FG-GAP repeat FUSC PF04632.12 OAI96592.1 - 0.025 13.2 1.1 0.026 13.1 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Retrotrans_gag PF03732.17 OAI96595.1 - 0.071 13.4 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Hydrolase_4 PF12146.8 OAI96604.1 - 0.0033 16.7 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAI96604.1 - 0.0038 17.0 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 OAI96604.1 - 0.0048 17.5 0.5 0.025 15.2 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAI96604.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAI96604.1 - 0.08 12.8 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 OAI96604.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TFIIA PF03153.13 OAI96609.1 - 4.6 7.1 10.8 6 6.8 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve PF00665.26 OAI96612.1 - 8.4e-18 64.7 0.1 1.6e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI96612.1 - 7.3e-11 42.0 0.2 2.2e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 OAI96612.1 - 0.0016 18.2 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DNA_pol_viral_C PF00336.18 OAI96623.1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.27 OAI96628.1 - 3.4e-30 105.2 0.0 4.5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 OAI96638.1 - 8.6e-24 84.3 0.0 3e-19 69.4 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAI96638.1 - 1.7e-12 47.1 0.0 3.8e-09 36.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase FA_synthesis PF02504.15 OAI96646.1 - 0.015 14.3 0.6 0.017 14.2 0.6 1.0 1 0 0 1 1 1 0 Fatty acid synthesis protein BBS2_C PF14782.6 OAI96646.1 - 0.086 11.6 0.1 0.085 11.6 0.1 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Mistic PF11458.8 OAI96646.1 - 0.13 12.3 0.1 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Membrane-integrating protein Mistic DUF4218 PF13960.6 OAI96652.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pkinase PF00069.25 OAI96655.1 - 1.3e-07 31.2 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ELFV_dehydrog_N PF02812.18 OAI96657.1 - 1.1e-17 64.2 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NEMP PF10225.9 OAI96659.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 NEMP family DUF4834 PF16118.5 OAI96659.1 - 0.037 15.0 0.0 0.047 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAD_binding_8 PF08022.12 OAI96662.1 - 1e-18 67.4 0.0 3e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 OAI96662.1 - 1.5e-14 54.4 0.0 1.8e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAI96662.1 - 3.9e-11 43.1 5.4 3.9e-11 43.1 5.4 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component rve PF00665.26 OAI96666.1 - 5.4e-16 58.8 0.0 1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OAI96666.1 - 0.0045 17.2 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 DDE domain MLVIN_C PF18697.1 OAI96666.1 - 0.014 15.5 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain LIDHydrolase PF10230.9 OAI96670.1 - 7.9e-46 156.8 0.0 3.1e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAI96670.1 - 5.5e-06 27.1 2.7 6.6e-06 26.9 1.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAI96670.1 - 3.9e-05 23.0 0.1 9.9e-05 21.7 0.1 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAI96670.1 - 0.028 14.3 0.2 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_3 PF07859.13 OAI96670.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAI96670.1 - 0.054 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DDE_Tnp_Tn3 PF01526.17 OAI96676.1 - 8.3e-93 311.2 0.1 9e-67 225.5 0.0 2.2 1 1 1 2 2 2 2 Tn3 transposase DDE domain DUF3288 PF11691.8 OAI96688.1 - 0.08 13.0 0.1 2 8.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3288) PSK_trans_fac PF07704.11 OAI96688.1 - 0.16 12.7 0.9 0.31 11.8 0.5 1.9 2 1 0 2 2 2 0 Rv0623-like transcription factor PilJ PF13675.6 OAI96690.1 - 0.21 11.6 2.4 19 5.3 0.0 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Myc_N PF01056.18 OAI96694.1 - 0.00073 19.5 2.4 0.00092 19.2 1.9 1.4 2 0 0 2 2 2 1 Myc amino-terminal region NOA36 PF06524.12 OAI96694.1 - 0.034 13.5 1.0 0.043 13.2 1.0 1.1 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.14 OAI96694.1 - 0.051 14.1 15.1 0.076 13.5 15.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ribosomal_60s PF00428.19 OAI96694.1 - 0.085 13.5 12.6 0.15 12.7 12.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2201_N PF13203.6 OAI96694.1 - 0.18 11.4 0.8 0.2 11.2 0.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CENP-B_dimeris PF09026.10 OAI96694.1 - 0.19 12.1 5.1 0.13 12.7 3.4 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAI96694.1 - 1.3 7.1 6.4 1.8 6.5 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 OAI96694.1 - 5.3 6.4 7.9 7.1 6.0 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) UDPG_MGDP_dh PF00984.19 OAI96695.1 - 8.1e-20 70.8 0.0 9.7e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain PRRSV_Env PF02340.15 OAI96695.1 - 0.012 15.0 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 PRRSV putative envelope protein WD40 PF00400.32 OAI96700.1 - 9.3e-40 133.9 8.3 7.6e-08 32.9 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI96700.1 - 1e-08 35.3 0.0 0.014 15.7 0.0 4.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAI96700.1 - 0.00012 20.9 2.8 0.15 10.7 0.4 3.6 1 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OAI96700.1 - 0.054 12.8 0.0 2.8 7.2 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 OAI96700.1 - 0.091 11.7 0.1 4.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nif11 PF07862.11 OAI96701.1 - 0.021 15.1 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 Nif11 domain PilO PF04350.13 OAI96701.1 - 0.071 13.3 1.5 0.085 13.0 1.5 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO MMPL PF03176.15 OAI96701.1 - 0.11 11.4 0.2 0.11 11.4 0.2 1.0 1 0 0 1 1 1 0 MMPL family RVT_1 PF00078.27 OAI96706.1 - 2.4e-19 69.7 0.0 3.6e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LysR_substrate PF03466.20 OAI96709.1 - 8.2e-22 77.6 1.5 1.1e-21 77.2 0.5 1.7 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 OAI96709.1 - 2.1e-19 69.2 1.8 1.3e-18 66.7 0.8 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Oxidored_nitro PF00148.19 OAI96709.1 - 0.029 13.1 0.0 0.058 12.1 0.0 1.4 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase HTH_18 PF12833.7 OAI96710.1 - 4.4e-18 65.3 1.6 1.2e-17 63.9 1.6 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 OAI96710.1 - 6e-09 35.8 0.0 3.2e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family CTC1_2 PF15491.6 OAI96712.1 - 0.047 13.0 0.3 0.048 13.0 0.3 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Aldedh PF00171.22 OAI96714.1 - 1.3e-10 40.5 0.0 1.3e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family CRR7 PF12095.8 OAI96714.1 - 0.094 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 HsbA PF12296.8 OAI96717.1 - 1e-08 35.6 9.2 1.3e-08 35.3 9.2 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Dsl1_C PF11989.8 OAI96720.1 - 0.0045 16.7 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Inhibitor_I53 PF11714.8 OAI96720.1 - 0.0064 16.7 0.4 0.018 15.3 0.4 1.7 1 0 0 1 1 1 1 Thrombin inhibitor Madanin Herpes_DNAp_acc PF04929.12 OAI96720.1 - 2.8 6.8 6.1 5.3 5.9 6.1 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RVT_2 PF07727.14 OAI96722.1 - 5.8e-61 206.2 0.0 7.6e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI96722.1 - 7.7 6.3 7.9 4.5 7.1 1.4 2.9 3 1 0 3 3 3 0 Reverse transcriptase-like PTPA PF03095.15 OAI96726.1 - 2.1e-91 306.5 0.0 2.5e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TonB_dep_Rec PF00593.24 OAI96729.1 - 1.6e-36 127.2 10.0 2e-36 126.9 10.0 1.1 1 0 0 1 1 1 1 TonB dependent receptor Eno-Rase_FAD_bd PF07055.12 OAI96729.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Serine_protease PF18405.1 OAI96729.1 - 0.21 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease OMP_b-brl_3 PF14905.6 OAI96729.1 - 0.49 9.3 3.1 0.46 9.4 0.6 2.3 2 1 0 2 2 2 0 Outer membrane protein beta-barrel family LIP PF03583.14 OAI96732.1 - 1.3e-24 87.0 2.5 2.1e-24 86.3 2.5 1.3 1 0 0 1 1 1 1 Secretory lipase TPR_2 PF07719.17 OAI96733.1 - 9.5e-06 25.4 0.7 0.13 12.5 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAI96733.1 - 1.4e-05 25.5 15.2 0.04 14.7 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAI96733.1 - 5.8e-05 22.7 0.1 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAI96733.1 - 8.1e-05 22.8 8.7 0.19 12.1 0.5 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAI96733.1 - 0.00096 19.2 0.1 1.4 9.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAI96733.1 - 0.04 14.0 1.7 0.37 10.9 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAI96733.1 - 0.047 14.3 17.8 5.3 8.0 0.1 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Cation_efflux PF01545.21 OAI96733.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Cation efflux family TPR_10 PF13374.6 OAI96733.1 - 0.093 12.6 4.3 5.4 7.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAI96733.1 - 4.9 7.9 17.5 0.84 10.3 1.1 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat Cactin_mid PF10312.9 OAI96734.1 - 6e-11 42.4 0.3 6e-11 42.4 0.3 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin Integrase_H2C2 PF17921.1 OAI96739.1 - 6.3e-16 58.2 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI96739.1 - 1.2e-11 44.8 0.0 2.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAI96739.1 - 3.7e-11 43.2 0.0 1.1e-10 41.7 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI96739.1 - 3.1e-06 27.2 0.1 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAI96739.1 - 0.038 14.2 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Erythro-docking PF09277.11 OAI96740.1 - 1 9.3 5.7 3.8 7.5 0.8 2.4 1 1 1 2 2 2 0 Erythronolide synthase, docking MULE PF10551.9 OAI96742.1 - 2.8e-06 27.6 0.0 7.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Collagen PF01391.18 OAI96744.1 - 0.00048 19.8 2.6 0.00067 19.4 2.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ABC_tran PF00005.27 OAI96750.1 - 8.5e-20 71.7 0.8 2.1e-19 70.4 0.0 2.1 3 0 0 3 3 3 1 ABC transporter ABC_trans_N PF14510.6 OAI96750.1 - 7.4e-12 45.7 0.3 1.7e-11 44.6 0.3 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal Cas_Csy1 PF09611.10 OAI96750.1 - 0.036 13.1 0.1 0.063 12.3 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) ABC2_membrane PF01061.24 OAI96750.1 - 0.062 12.7 0.1 0.062 12.7 0.1 1.9 3 0 0 3 3 3 0 ABC-2 type transporter T3SSipB PF16535.5 OAI96753.1 - 2.8e-05 24.7 3.6 7.7e-05 23.2 3.6 1.7 1 0 0 1 1 1 1 Type III cell invasion protein SipB KxDL PF10241.9 OAI96753.1 - 0.012 15.8 6.3 0.027 14.7 6.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF3435 PF11917.8 OAI96756.1 - 0.89 8.4 7.6 1.2 8.0 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) HlyD_3 PF13437.6 OAI96774.1 - 0.038 14.7 0.0 0.052 14.2 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein eIF3_N PF09440.10 OAI96775.1 - 0.0015 19.0 0.1 0.0021 18.5 0.1 1.1 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain DUF4287 PF14117.6 OAI96775.1 - 0.097 12.8 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) BLOC1S3 PF15753.5 OAI96778.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 FHA PF00498.26 OAI96784.1 - 0.049 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 FHA domain Retrotrans_gag PF03732.17 OAI96788.1 - 0.068 13.4 0.3 0.068 13.4 0.3 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein TMF_DNA_bd PF12329.8 OAI96788.1 - 2.1 8.4 13.6 1.3 9.1 7.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lipase_GDSL_2 PF13472.6 OAI96790.1 - 0.00075 19.9 0.1 0.0015 19.0 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family rve PF00665.26 OAI96799.1 - 5e-17 62.2 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAI96799.1 - 1.6e-07 31.0 0.2 6.8e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain S100PBPR PF15427.6 OAI96799.1 - 0.024 13.9 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 S100P-binding protein rve_3 PF13683.6 OAI96799.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH_2 PF17919.1 OAI96804.1 - 1.6e-32 111.5 0.0 4e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI96804.1 - 2.6e-30 104.8 0.0 7.3e-30 103.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI96804.1 - 7.6e-19 68.1 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAI96804.1 - 0.11 13.1 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Fer4 PF00037.27 OAI96806.1 - 5.7e-15 54.4 16.4 8.9e-09 34.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAI96806.1 - 2.2e-13 50.5 10.4 3.4e-13 49.9 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAI96806.1 - 5.6e-11 43.2 8.6 9.1e-06 26.5 0.8 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAI96806.1 - 3.9e-10 39.7 6.8 6.9e-05 22.9 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAI96806.1 - 6.1e-10 39.1 21.6 1.3e-06 28.4 12.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAI96806.1 - 2.5e-09 37.4 3.1 7.2e-05 23.2 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAI96806.1 - 4.5e-09 36.3 10.2 7.7e-09 35.6 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OAI96806.1 - 1.2e-07 31.5 17.8 0.00021 21.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OAI96806.1 - 3.8e-07 29.8 12.5 0.0014 18.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAI96806.1 - 1.6e-06 28.2 10.8 0.00017 21.8 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAI96806.1 - 4.3e-05 24.0 10.9 0.0085 16.6 11.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 OAI96806.1 - 0.00012 22.6 9.8 0.056 14.0 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OAI96806.1 - 0.0025 18.0 4.9 0.4 10.9 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OAI96806.1 - 0.015 15.5 9.3 5.7 7.2 8.0 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAI96806.1 - 0.064 14.2 16.3 0.19 12.8 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 OAI96806.1 - 0.083 13.7 11.4 1.3 10.0 1.7 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 OAI96806.1 - 0.11 12.6 6.3 0.88 9.7 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 OAI96806.1 - 0.38 10.8 6.7 0.4 10.7 0.8 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins DUF11 PF01345.18 OAI96810.1 - 0.045 14.1 4.1 6.5 7.1 1.2 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF11 FAM199X PF15814.5 OAI96812.1 - 0.52 9.3 6.2 0.54 9.3 6.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X Phage_integrase PF00589.22 OAI96817.1 - 6e-06 26.2 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF2716 PF10898.8 OAI96817.1 - 0.11 12.9 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) DNA_pol3_tau_4 PF12168.8 OAI96818.1 - 0.06 13.9 0.8 0.43 11.1 0.4 2.2 1 1 1 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding MMU163 PF17119.5 OAI96821.1 - 6.1 5.9 8.1 12 4.9 8.1 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis adh_short PF00106.25 OAI96834.1 - 8e-07 28.7 0.0 3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAI96834.1 - 0.016 15.1 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 KR domain zf-CCHC PF00098.23 OAI96837.1 - 0.001 19.0 1.5 0.001 19.0 1.5 2.0 2 0 0 2 2 2 1 Zinc knuckle SWIM PF04434.17 OAI96837.1 - 0.0015 18.1 1.0 0.0038 16.8 1.0 1.7 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_5 PF14787.6 OAI96837.1 - 0.023 14.4 1.1 0.065 13.0 1.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 OAI96837.1 - 0.054 13.5 0.3 0.054 13.5 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle DBD_Tnp_Mut PF03108.15 OAI96838.1 - 3.4e-07 30.1 0.4 7e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 MuDR family transposase Glyco_hyd_65N_2 PF14498.6 OAI96838.1 - 0.075 12.9 0.6 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PQQ_2 PF13360.6 OAI96840.1 - 0.054 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 OAI96840.1 - 0.075 13.0 0.8 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat Frag1 PF10277.9 OAI96842.1 - 3.8e-26 92.0 14.0 5.3e-26 91.5 14.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family AC_N PF16214.5 OAI96842.1 - 0.0028 16.8 5.8 0.0028 16.8 5.8 1.4 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region MIG-14_Wnt-bd PF06664.12 OAI96842.1 - 0.81 8.8 11.2 0.11 11.7 4.6 2.0 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion TMEM192 PF14802.6 OAI96842.1 - 0.94 8.5 5.5 2.4 7.2 2.4 2.2 1 1 1 2 2 2 0 TMEM192 family Integrase_H2C2 PF17921.1 OAI96853.1 - 1.9e-16 59.9 0.0 3.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAI96853.1 - 6.8e-15 54.9 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAI96853.1 - 1.9e-11 44.2 0.0 4.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAI96853.1 - 1.7e-08 34.3 0.0 3.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAI96853.1 - 0.00085 19.6 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAI96853.1 - 0.016 15.5 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger zf-FPG_IleRS PF06827.14 OAI96868.1 - 0.021 14.7 10.3 0.074 12.9 10.3 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS RecR PF02132.15 OAI96868.1 - 0.045 13.3 2.2 0.08 12.5 2.2 1.4 1 0 0 1 1 1 0 RecR protein OrfB_Zn_ribbon PF07282.11 OAI96868.1 - 0.077 12.9 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YchF-GTPase_C PF06071.13 OAI96868.1 - 0.13 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Mpv17_PMP22 PF04117.12 OAI96869.1 - 1e-24 86.5 2.9 2.4e-24 85.3 2.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF5048 PF16467.5 OAI96869.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) BBE PF08031.12 OAI96871.1 - 0.00035 20.6 0.2 0.0005 20.1 0.2 1.2 1 0 0 1 1 1 1 Berberine and berberine like PIN_4 PF13638.6 OAI96872.1 - 3.7e-10 40.2 0.0 6.3e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 PIN domain IFT43 PF15305.6 OAI96877.1 - 0.99 9.6 7.6 0.12 12.5 3.3 1.6 2 0 0 2 2 2 0 Intraflagellar transport protein 43 HBS1_N PF08938.10 OAI96880.1 - 0.042 14.1 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus SLATT_fungal PF18142.1 OAI96880.1 - 0.12 12.4 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain EF-hand_10 PF14788.6 OAI96880.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 EF hand GP24_25 PF17388.2 OAI96880.1 - 0.21 11.6 0.9 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 ORC6 PF05460.13 OAI96885.1 - 1.8 7.7 9.3 0.042 13.1 2.5 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF2798 PF11391.8 OAI96889.1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) CPT PF07931.12 OAI96892.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Glyco_hydro_45 PF02015.16 OAI96893.1 - 6e-16 59.0 0.1 7.3e-16 58.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 UBA2_C PF16195.5 OAI96895.1 - 0.002 18.7 4.8 0.0028 18.3 4.8 1.2 1 0 0 1 1 1 1 SUMO-activating enzyme subunit 2 C-terminus AF-4 PF05110.13 OAI96896.1 - 2 6.4 8.0 3.1 5.8 8.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AIRC PF00731.20 OAI96897.1 - 4.7e-07 29.5 0.0 5.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 AIR carboxylase HSBP1 PF06825.12 OAI96897.1 - 0.015 15.2 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ABC_trans_aux PF03886.13 OAI96897.1 - 0.073 12.6 0.0 0.087 12.4 0.0 1.0 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Ribosomal_L29 PF00831.23 OAI96901.1 - 0.00033 20.6 1.5 0.00056 19.8 1.5 1.4 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 OAI96901.1 - 0.00041 20.4 2.2 0.00088 19.3 2.2 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF733 PF05306.11 OAI96901.1 - 0.018 15.3 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Proteasome PF00227.26 OAI96902.1 - 2.1e-21 76.3 0.1 4.2e-21 75.3 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Pr_beta_C PF12465.8 OAI96902.1 - 1.1e-06 27.9 0.1 2.2e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Proteasome PF00227.26 OAI96904.1 - 1.4e-48 164.9 0.2 2e-48 164.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2188 PF09954.9 OAI96904.1 - 0.0013 18.9 0.4 0.059 13.5 0.2 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2188) Ntox44 PF15607.6 OAI96904.1 - 0.11 12.8 0.3 3.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial toxin 44 Yos1 PF08571.10 OAI96907.1 - 4.5e-30 103.7 0.9 6.2e-30 103.3 0.9 1.2 1 0 0 1 1 1 1 Yos1-like CH PF00307.31 OAI96908.1 - 1.2e-05 25.4 0.1 1.6e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 OAI96908.1 - 0.028 14.5 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 CH-like domain in sperm protein GMC_oxred_C PF05199.13 OAI96913.1 - 8.2e-37 126.9 0.0 1.4e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAI96913.1 - 1.8e-22 80.1 0.0 2.5e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase RT_RNaseH_2 PF17919.1 OAI96919.1 - 3.2e-26 91.3 0.0 6.2e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI96919.1 - 1.1e-23 83.5 0.0 2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI96919.1 - 3e-16 59.6 0.0 5.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAI96919.1 - 0.11 13.1 0.0 0.4 11.3 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 OAI96922.1 - 8.7e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAD_2 PF13419.6 OAI96925.1 - 1.7e-12 47.8 0.0 3.8e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAI96925.1 - 3.2e-08 34.1 0.0 1.4e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAI96925.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAI96925.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 OAI96932.1 - 1.4e-13 50.5 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 P35 PF02331.15 OAI96944.1 - 0.047 13.0 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein RVT_1 PF00078.27 OAI96955.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAI96957.1 - 0.00014 22.1 0.4 0.00033 20.9 0.0 1.8 2 0 0 2 2 2 1 RNase H Tim54 PF11711.8 OAI96957.1 - 0.0056 15.5 3.1 0.0075 15.1 3.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DnaJ PF00226.31 OAI96957.1 - 0.012 15.7 1.7 0.024 14.7 0.0 2.4 3 1 0 3 3 3 0 DnaJ domain Presenilin PF01080.17 OAI96957.1 - 0.02 13.7 3.2 0.024 13.4 3.2 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OAI96957.1 - 0.072 11.9 3.8 0.085 11.6 3.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 OAI96957.1 - 0.18 11.0 0.3 0.22 10.7 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 OAI96957.1 - 0.2 10.3 1.1 0.23 10.1 1.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Connexin PF00029.19 OAI96957.1 - 0.54 10.0 1.2 0.75 9.5 1.2 1.3 1 0 0 1 1 1 0 Connexin PDDEXK_9 PF08011.11 OAI96957.1 - 2.1 8.3 7.3 7.6 6.5 7.6 1.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Neur_chan_memb PF02932.16 OAI96957.1 - 4 7.4 5.4 5.7 6.9 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 OAI96957.1 - 8.7 6.1 12.2 11 5.8 12.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 OAI96957.1 - 9.1 4.4 11.2 11 4.1 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DHquinase_II PF01220.19 OAI96963.1 - 3.4e-35 120.7 0.0 4.5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Dehydroquinase class II PCNA_N PF00705.18 OAI96963.1 - 0.19 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain DHquinase_II PF01220.19 OAI96964.1 - 5.4e-33 113.6 0.2 5.9e-33 113.5 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II LRR_8 PF13855.6 OAI96965.1 - 1.2e-05 25.0 7.5 6.3e-05 22.7 0.9 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAI96965.1 - 0.001 19.4 2.9 0.57 10.7 0.2 2.2 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) CAP_N PF01213.19 OAI96965.1 - 9.7 5.6 7.1 14 5.0 7.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Na_Ca_ex PF01699.24 OAI96968.1 - 3.3e-13 49.8 4.0 4.1e-13 49.6 4.0 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein OATP PF03137.20 OAI96968.1 - 0.053 11.8 0.7 0.071 11.4 0.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NAD_binding_10 PF13460.6 OAI96972.1 - 0.0074 16.2 0.3 0.056 13.3 0.3 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Maf PF02545.14 OAI96972.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.6 1 1 0 1 1 1 0 Maf-like protein DBD_HTH PF18430.1 OAI96976.1 - 0.11 12.2 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 Putative DNA-binding domain Astro_capsid_p PF12226.8 OAI96976.1 - 0.31 10.1 8.3 0.51 9.4 8.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 OAI96976.1 - 5.1 5.2 11.7 7.3 4.7 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 OAI96979.1 - 0.84 8.1 2.7 0.92 8.0 2.7 1.0 1 0 0 1 1 1 0 Macoilin family DUF3772 PF12607.8 OAI96981.1 - 0.059 13.1 4.9 0.4 10.5 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) MitMem_reg PF13012.6 OAI96995.1 - 2.8e-28 98.6 0.4 7.7e-28 97.2 0.2 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAI96995.1 - 5.5e-17 61.8 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DDE_Tnp_4 PF13359.6 OAI96998.1 - 1.9e-16 60.1 0.0 2.2e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease COG5 PF10392.9 OAI96999.1 - 0.014 15.6 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Myb_DNA-bind_5 PF13873.6 OAI96999.1 - 0.041 14.0 0.2 0.15 12.1 0.2 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain YL1 PF05764.13 OAI96999.1 - 0.045 13.9 2.8 0.062 13.4 2.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 OAI96999.1 - 0.12 11.7 12.8 0.18 11.1 12.8 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OAI96999.1 - 0.19 11.1 5.4 0.24 10.8 5.4 1.1 1 0 0 1 1 1 0 SDA1 CNDH2_C PF16858.5 OAI96999.1 - 0.19 11.6 2.3 0.26 11.1 2.3 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 OAI96999.1 - 0.39 8.9 8.4 0.61 8.2 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.10 OAI96999.1 - 0.58 10.9 14.9 1.1 10.0 14.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFIIF_alpha PF05793.12 OAI96999.1 - 0.95 8.0 12.8 1.3 7.6 12.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 OAI96999.1 - 9.7 5.8 12.8 14 5.3 12.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TipE PF16972.5 OAI96999.1 - 9.7 5.2 6.6 14 4.7 6.6 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE SWIM PF04434.17 OAI97002.1 - 0.044 13.4 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 SWIM zinc finger Glyco_transf_20 PF00982.21 OAI97005.1 - 2e-124 415.8 0.0 2.7e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 OAI97005.1 - 0.055 13.0 0.2 3.9 7.0 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 RVT_1 PF00078.27 OAI97007.1 - 6.6e-21 74.9 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Keratin_2_head PF16208.5 OAI97011.1 - 0.0033 17.6 5.4 0.012 15.7 5.4 1.9 1 0 0 1 1 1 1 Keratin type II head Med3 PF11593.8 OAI97011.1 - 0.0088 15.3 8.9 0.0088 15.3 8.9 4.5 3 1 1 4 4 4 1 Mediator complex subunit 3 fungal RNase_H2_suC PF08615.11 OAI97011.1 - 0.44 10.7 3.9 1.8 8.7 0.0 2.7 2 2 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CDC45 PF02724.14 OAI97011.1 - 2.3 6.4 10.4 1.5 7.1 0.3 3.0 3 0 0 3 3 3 0 CDC45-like protein DUF659 PF04937.15 OAI97016.1 - 8.8e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RTC_insert PF05189.13 OAI97016.1 - 0.0038 17.7 0.2 0.011 16.3 0.1 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Astro_capsid_p PF12226.8 OAI97016.1 - 0.013 14.7 0.3 0.022 13.9 0.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Na_trans_assoc PF06512.13 OAI97016.1 - 0.024 14.9 2.1 0.044 14.1 2.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 OAI97016.1 - 0.038 13.4 9.3 0.054 12.8 9.3 1.1 1 0 0 1 1 1 0 BUD22 DBD_Tnp_Hermes PF10683.9 OAI97016.1 - 0.16 11.7 0.1 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain PP2C PF00481.21 OAI97021.1 - 1.7e-83 280.2 0.0 2.8e-83 279.5 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C TPR_10 PF13374.6 OAI97024.1 - 1.1e-07 31.5 3.8 3.6e-06 26.6 0.8 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAI97024.1 - 4.9e-07 29.9 7.8 0.00026 21.2 2.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAI97024.1 - 0.00032 20.6 0.3 0.057 13.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAI97024.1 - 0.0076 16.4 0.5 5 7.6 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Transposase_20 PF02371.16 OAI97028.1 - 5.9e-18 65.0 0.0 1.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 OAI97028.1 - 3.5e-07 30.2 0.0 6.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Transposase Bmt2 PF11968.8 OAI97032.1 - 1.3e-43 149.5 0.0 6.7e-26 91.5 0.0 2.2 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 SMC_ScpB PF04079.16 OAI97034.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB RVT_1 PF00078.27 OAI97043.1 - 0.065 12.7 0.1 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.14 OAI97052.1 - 1e-08 34.7 0.0 2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 zf-Di19 PF05605.12 OAI97054.1 - 0.17 12.2 1.2 1 9.7 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-WRNIP1_ubi PF18279.1 OAI97054.1 - 0.39 11.5 2.2 6 7.8 0.0 2.4 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF4218 PF13960.6 OAI97057.1 - 0.00042 19.9 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ACPS PF01648.20 OAI97069.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Sec1 PF00995.23 OAI97071.1 - 1.3e-82 278.9 0.0 1.9e-82 278.4 0.0 1.2 1 0 0 1 1 1 1 Sec1 family Mito_carr PF00153.27 OAI97074.1 - 1.4e-61 204.4 6.2 7.9e-21 73.8 0.0 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF5331 PF17265.2 OAI97074.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5331) MULE PF10551.9 OAI97080.1 - 2e-20 73.0 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAI97080.1 - 1.2e-09 37.6 0.0 2.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family rve PF00665.26 OAI97080.1 - 0.056 13.6 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Ntox3 PF15536.6 OAI97080.1 - 0.085 12.9 0.1 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial toxin 3 LMBR1 PF04791.16 OAI97082.1 - 1.4 7.8 7.3 1.5 7.6 7.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein HSP70 PF00012.20 OAI97086.1 - 9.9e-10 37.2 1.3 3.2e-06 25.6 0.3 2.0 1 1 0 2 2 2 2 Hsp70 protein Peptidase_C48 PF02902.19 OAI97092.1 - 7.6e-08 32.5 0.5 6.5e-07 29.4 0.0 2.4 1 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 OAI97093.1 - 0.016 16.0 16.6 0.25 12.3 0.2 4.6 4 2 0 4 4 4 0 WD domain, G-beta repeat CENP-B_dimeris PF09026.10 OAI97093.1 - 0.49 10.8 9.7 1.1 9.6 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tannase PF07519.11 OAI97095.1 - 2e-26 92.9 0.0 2.6e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase MT-A70 PF05063.14 OAI97098.1 - 2.1e-06 27.8 0.0 0.0027 17.7 0.1 3.1 2 1 0 2 2 2 2 MT-A70 HSP70 PF00012.20 OAI97100.1 - 4.7e-07 28.4 0.2 5.7e-07 28.1 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein RVT_3 PF13456.6 OAI97106.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_int_SAM_1 PF02899.17 OAI97107.1 - 0.0038 17.5 0.0 0.0059 16.9 0.0 1.4 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain MIP PF00230.20 OAI97113.1 - 0.068 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Major intrinsic protein STAR_dimer PF16544.5 OAI97113.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein RdRP_2 PF00978.21 OAI97115.1 - 1.2e-13 50.7 0.0 1.6e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Serpin PF00079.20 OAI97115.1 - 0.036 13.4 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) RT_RNaseH PF17917.1 OAI97124.1 - 4.6e-12 46.2 0.0 8.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI97124.1 - 4.4e-06 26.7 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SDA1 PF05285.12 OAI97127.1 - 0.00072 19.1 15.9 0.00078 19.0 15.9 1.1 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.12 OAI97127.1 - 0.0026 17.2 25.8 0.0033 16.8 25.8 1.1 1 0 0 1 1 1 1 NOA36 protein Nop14 PF04147.12 OAI97127.1 - 0.0067 14.7 16.6 0.0073 14.6 16.6 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 OAI97127.1 - 0.014 14.8 16.4 0.016 14.5 16.4 1.2 1 0 0 1 1 1 0 BUD22 Myb_DNA-bind_5 PF13873.6 OAI97127.1 - 0.087 12.9 0.0 0.54 10.4 0.1 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Tub_N PF16322.5 OAI97127.1 - 0.11 12.9 2.7 0.15 12.4 2.7 1.3 1 0 0 1 1 1 0 Tubby N-terminal PPP4R2 PF09184.11 OAI97127.1 - 0.13 11.8 16.1 0.17 11.4 16.1 1.2 1 0 0 1 1 1 0 PPP4R2 Nop25 PF09805.9 OAI97127.1 - 1.1 9.8 8.5 2 8.9 8.5 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DNA_pol_phi PF04931.13 OAI97127.1 - 3.4 5.7 30.6 5.2 5.1 30.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 OAI97127.1 - 5.6 6.6 7.2 7 6.3 7.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RPA PF10134.9 OAI97132.1 - 4.7e-14 52.4 0.0 5.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Replication initiator protein A zinc_ribbon_11 PF11682.8 OAI97136.1 - 0.027 14.5 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon Lipocalin_5 PF13924.6 OAI97136.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipocalin-like domain NitrOD2 PF18550.1 OAI97140.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Nitrososphaera output domain 2 RecX PF02631.16 OAI97141.1 - 0.023 15.1 0.5 0.066 13.7 0.5 1.7 1 0 0 1 1 1 0 RecX family Pedibin PF08182.11 OAI97141.1 - 0.031 14.1 1.0 0.031 14.1 1.0 1.8 2 0 0 2 2 2 0 Pedibin/Hym-346 family DUF5082 PF16888.5 OAI97141.1 - 0.042 14.1 1.4 0.093 13.0 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Ax_dynein_light PF10211.9 OAI97141.1 - 0.51 10.3 6.8 0.86 9.5 6.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Catalase PF00199.19 OAI97142.1 - 3.9e-27 95.3 0.1 4.2e-27 95.2 0.1 1.0 1 0 0 1 1 1 1 Catalase BATS PF06968.13 OAI97146.1 - 3.1e-19 68.9 0.1 1.6e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAI97146.1 - 8.3e-13 49.1 0.1 1.4e-12 48.4 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily FHA PF00498.26 OAI97151.1 - 0.094 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 FHA domain SOG2 PF10428.9 OAI97151.1 - 5.1 6.2 16.7 6.5 5.8 16.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_17 PF13207.6 OAI97155.1 - 0.071 13.5 5.2 0.11 12.9 5.2 1.4 1 0 0 1 1 1 0 AAA domain PRTP PF01366.18 OAI97155.1 - 4.4 5.2 7.4 5.7 4.9 7.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RVT_3 PF13456.6 OAI97160.1 - 0.041 13.7 0.1 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like HTH_40 PF14493.6 OAI97168.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_C53 PF05550.11 OAI97169.1 - 0.0092 15.7 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Pestivirus Npro endopeptidase C53 Phage_integrase PF00589.22 OAI97170.1 - 0.0052 16.6 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAI97171.1 - 0.082 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 OAI97185.1 - 1.6e-18 67.1 0.1 3.7e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 OAI97185.1 - 4.1e-10 39.9 1.6 1.4e-09 38.2 1.6 2.0 1 0 0 1 1 1 1 Arm DNA-binding domain MCM PF00493.23 OAI97191.1 - 1.8e-39 135.1 0.2 2.2e-39 134.8 0.2 1.1 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 OAI97191.1 - 0.00054 19.4 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF5555 PF17710.1 OAI97195.1 - 0.05 13.1 5.8 0.081 12.4 0.6 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5555) FYVE PF01363.21 OAI97197.1 - 3.5e-11 43.1 3.8 5.5e-11 42.4 3.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger Pkinase PF00069.25 OAI97200.1 - 5.7e-19 68.5 0.0 6.5e-09 35.5 0.0 4.1 2 2 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97200.1 - 4e-11 42.7 0.0 6.7e-08 32.1 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAI97200.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chlam_PMP PF02415.17 OAI97200.1 - 0.28 11.7 4.1 3.9 8.2 0.0 4.2 3 1 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pinin_SDK_N PF04697.13 OAI97200.1 - 4.4 8.0 6.9 5.6 7.6 2.7 2.4 2 0 0 2 2 2 0 pinin/SDK conserved region Sec23_trunk PF04811.15 OAI97205.1 - 7.4e-72 241.8 0.0 1.3e-71 241.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAI97205.1 - 2e-16 59.7 0.2 5.5e-16 58.3 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAI97205.1 - 2.9e-16 59.2 8.1 5.7e-16 58.3 8.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OAI97205.1 - 1.7e-07 31.9 0.0 5.4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Vps36-NZF-N PF16988.5 OAI97205.1 - 0.0068 15.8 2.3 0.013 14.8 2.3 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF4618 PF15397.6 OAI97210.1 - 0.0054 16.2 0.3 0.0054 16.2 0.3 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4618) DUF948 PF06103.11 OAI97210.1 - 0.047 13.9 7.0 3 8.2 0.1 5.3 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) RVP_2 PF08284.11 OAI97212.1 - 3.6e-08 33.2 0.0 6.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAI97212.1 - 8e-05 23.1 0.0 0.00014 22.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 OAI97212.1 - 0.00018 21.4 1.5 0.00018 21.4 1.5 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAI97212.1 - 0.00027 20.8 0.1 0.00063 19.7 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 OAI97212.1 - 0.00053 19.8 0.5 0.0014 18.4 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAI97212.1 - 0.0022 17.8 0.5 0.0046 16.7 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAI97212.1 - 0.027 14.7 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 OAI97212.1 - 0.049 14.3 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease CLIP1_ZNF PF16641.5 OAI97212.1 - 0.12 12.3 0.7 0.24 11.3 0.7 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle Trans_coact PF16805.5 OAI97214.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage late-transcription coactivator VID27 PF08553.10 OAI97216.1 - 2e-114 382.4 0.0 2.3e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Methyltransf_PK PF05891.12 OAI97219.1 - 2.7e-49 167.6 0.0 1.1e-15 57.8 0.0 4.2 3 1 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OAI97219.1 - 0.0006 20.5 0.0 1.2 9.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAI97219.1 - 0.0011 19.7 0.0 1.1 10.0 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OAI97219.1 - 0.0018 18.1 0.1 0.011 15.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain MRVI1 PF05781.12 OAI97219.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 MRVI1 protein CDC45 PF02724.14 OAI97219.1 - 0.28 9.4 3.9 1.7 6.8 0.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Ras PF00071.22 OAI97224.1 - 5.6e-05 22.8 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ras family DNA_ligase_OB_2 PF14743.6 OAI97224.1 - 0.00045 20.2 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 DNA ligase OB-like domain Roc PF08477.13 OAI97224.1 - 0.011 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Transglut_core3 PF13471.6 OAI97228.1 - 4.3e-17 62.1 0.3 4.5e-17 62.0 0.3 1.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core PF01841.19 OAI97228.1 - 0.0036 17.7 0.1 0.0045 17.4 0.1 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transposase_21 PF02992.14 OAI97234.1 - 7.5e-11 41.7 0.2 1.9e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4422 PF14393.6 OAI97234.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Melittin PF01372.17 OAI97237.1 - 0.037 14.0 0.2 0.037 14.0 0.2 1.9 2 0 0 2 2 2 0 Melittin Spore_III_AF PF09581.10 OAI97237.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TFIIA PF03153.13 OAI97237.1 - 0.27 11.2 10.7 29 4.5 0.0 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.6 OAI97237.1 - 3.2 6.5 5.9 0.95 8.2 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) RVT_1 PF00078.27 OAI97239.1 - 2.1e-22 79.7 0.0 3.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI97239.1 - 8e-16 57.9 0.0 2.1e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI97239.1 - 0.0055 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase dUTPase PF00692.19 OAI97239.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 dUTPase COesterase PF00135.28 OAI97241.1 - 3.3e-35 121.9 0.0 3.8e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAI97241.1 - 2.9e-05 24.0 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cbl_N PF02262.16 OAI97248.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.3 1 1 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 XPC-binding PF09280.11 OAI97252.1 - 0.084 12.6 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 XPC-binding domain NUDIX PF00293.28 OAI97253.1 - 2e-25 89.4 0.0 2.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FAD_binding_2 PF00890.24 OAI97267.1 - 2.4e-48 165.2 0.1 2.9e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAI97267.1 - 3.5e-14 53.1 1.8 1.6e-13 50.9 1.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAI97267.1 - 1e-10 41.7 0.9 8.1e-10 38.8 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAI97267.1 - 4.6e-08 32.8 0.7 6.2e-08 32.4 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAI97267.1 - 6.8e-08 32.1 0.1 1.5e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAI97267.1 - 6.2e-07 28.5 0.1 3.7e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAI97267.1 - 7.7e-07 28.5 0.8 0.0012 18.1 0.3 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAI97267.1 - 1.8e-06 27.4 0.7 3.2e-06 26.6 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAI97267.1 - 2.2e-06 27.1 0.1 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAI97267.1 - 0.0001 21.6 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAI97267.1 - 0.00014 21.3 0.1 0.00071 19.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAI97267.1 - 0.00029 21.4 0.6 0.005 17.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAI97267.1 - 0.00056 19.2 0.1 0.0013 18.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAI97267.1 - 0.0045 17.0 0.1 0.38 10.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAI97267.1 - 0.023 15.1 0.0 0.046 14.2 0.0 1.6 2 0 0 2 2 1 0 Putative NAD(P)-binding GDI PF00996.18 OAI97267.1 - 0.024 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.12 OAI97267.1 - 0.045 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 OAI97267.1 - 0.069 13.4 0.1 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain CRAL_TRIO PF00650.20 OAI97270.1 - 2.9e-13 49.9 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAI97270.1 - 6.1e-13 48.7 1.2 1.2e-12 47.7 1.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DNA_pol_A_exoN PF18305.1 OAI97270.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain CRAL_TRIO PF00650.20 OAI97271.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain HOIP-UBA PF16678.5 OAI97271.1 - 0.046 13.7 0.2 0.062 13.3 0.2 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair PCI PF01399.27 OAI97275.1 - 0.014 15.9 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 PCI domain RVT_3 PF13456.6 OAI97279.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Transposase_21 PF02992.14 OAI97284.1 - 1.6e-08 34.0 0.0 5.5e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Transposase family tnp2 FAD_binding_4 PF01565.23 OAI97289.1 - 4.4e-20 71.8 0.5 6.8e-20 71.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAI97289.1 - 0.0012 18.9 0.2 0.0026 17.8 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Phage_integrase PF00589.22 OAI97293.1 - 4.3e-05 23.4 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF1176 PF06674.11 OAI97297.1 - 0.053 13.0 0.1 0.059 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) MFS_1 PF07690.16 OAI97300.1 - 6.4e-33 114.1 57.3 5e-19 68.4 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAI97300.1 - 0.7 8.1 7.9 0.085 11.1 0.4 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OAI97300.1 - 4.7 5.7 29.6 0.014 14.0 8.1 2.5 1 1 1 2 2 2 0 MFS/sugar transport protein Fer2 PF00111.27 OAI97301.1 - 4.2e-14 52.3 0.8 5e-14 52.0 0.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CDCA PF18484.1 OAI97301.1 - 0.045 13.6 0.2 0.059 13.2 0.2 1.4 1 1 0 1 1 1 0 Cadmium carbonic anhydrase repeat Pyr_redox_2 PF07992.14 OAI97302.1 - 4.7e-10 39.2 0.0 5e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAI97302.1 - 0.0061 15.6 0.0 0.0076 15.3 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAI97302.1 - 0.018 15.3 0.2 0.03 14.5 0.2 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAI97302.1 - 0.065 12.5 0.3 0.086 12.1 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAI97302.1 - 0.081 13.5 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAI97302.1 - 0.098 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.6 OAI97302.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OAI97302.1 - 0.11 11.3 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 OAI97302.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 OAI97302.1 - 0.15 11.7 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 OAI97302.1 - 0.29 9.8 0.4 0.35 9.5 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein TarH PF02203.15 OAI97303.1 - 0.00034 20.6 0.9 0.0004 20.4 0.9 1.2 1 0 0 1 1 1 1 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.7 OAI97303.1 - 0.00093 18.8 2.8 0.0048 16.5 2.8 2.1 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF3053 PF11254.8 OAI97303.1 - 0.0044 16.6 0.2 0.0054 16.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) HNH_2 PF13391.6 OAI97307.1 - 0.0077 16.3 0.1 0.012 15.8 0.1 1.4 1 1 0 1 1 1 1 HNH endonuclease FHA PF00498.26 OAI97307.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 FHA domain Phage_holin_2_1 PF04971.12 OAI97312.1 - 0.0068 16.4 0.1 0.0068 16.4 0.1 1.6 2 0 0 2 2 2 1 Bacteriophage P21 holin S DUF202 PF02656.15 OAI97312.1 - 0.16 12.4 2.5 0.44 11.0 2.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) AMMECR1 PF01871.17 OAI97315.1 - 4.3e-47 159.8 0.0 5.3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Retrotran_gag_2 PF14223.6 OAI97318.1 - 6.1e-24 84.3 0.3 1.1e-23 83.5 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAI97318.1 - 3.1e-15 56.4 0.0 9.4e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 OAI97318.1 - 2.1e-07 30.7 1.6 5.1e-07 29.5 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 OAI97318.1 - 1.7e-06 27.8 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAI97318.1 - 0.00022 20.9 0.2 0.00073 19.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Prp31_C PF09785.9 OAI97318.1 - 0.045 14.7 0.6 0.28 12.1 0.0 2.5 3 0 0 3 3 3 0 Prp31 C terminal domain OmpH PF03938.14 OAI97321.1 - 0.28 11.5 8.9 0.37 11.1 8.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L37 PF08561.10 OAI97321.1 - 0.98 10.0 9.6 1.7 9.2 9.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF4407 PF14362.6 OAI97321.1 - 0.99 8.7 9.2 1.3 8.3 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 OAI97323.1 - 2.4e-08 34.0 0.0 4.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAI97323.1 - 1.3e-07 32.0 0.0 1e-06 29.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAI97323.1 - 0.0012 18.8 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAI97323.1 - 0.056 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAI97323.1 - 0.18 12.2 0.0 0.35 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Utp14 PF04615.13 OAI97336.1 - 0.63 8.6 21.7 0.69 8.4 21.7 1.0 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 OAI97336.1 - 1.1 7.3 32.1 1.2 7.1 32.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFAP1 PF06991.11 OAI97336.1 - 3.2 7.5 18.5 3.9 7.3 18.5 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing CDC45 PF02724.14 OAI97336.1 - 6.8 4.9 25.1 6.8 4.8 25.1 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 OAI97336.1 - 8.2 4.9 29.5 9.3 4.7 29.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) rve PF00665.26 OAI97340.1 - 4.3e-14 52.7 0.0 7.3e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.22 OAI97345.1 - 1.4e-36 124.1 0.0 3.6e-16 58.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.12 OAI97345.1 - 0.078 12.4 25.5 0.24 10.8 25.5 1.8 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 OAI97345.1 - 0.2 10.9 27.6 0.44 9.8 27.6 1.5 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 OAI97345.1 - 0.37 10.4 26.1 0.74 9.3 26.1 1.4 1 0 0 1 1 1 0 PPP4R2 PIEZO PF15917.5 OAI97345.1 - 0.53 9.7 10.2 0.069 12.6 6.1 1.6 2 0 0 2 2 2 0 Piezo Nop14 PF04147.12 OAI97345.1 - 1.2 7.2 30.3 2 6.5 30.3 1.2 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.9 OAI97345.1 - 7.6 7.0 27.5 0.25 11.8 19.2 2.6 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) Syntaphilin PF15290.6 OAI97347.1 - 0.031 13.9 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp TAF4 PF05236.14 OAI97348.1 - 0.14 11.9 2.0 0.35 10.6 2.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IATP PF04568.12 OAI97348.1 - 3.9 8.0 7.6 8.4 6.9 6.8 2.0 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP RGS PF00615.19 OAI97350.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Phage_int_SAM_1 PF02899.17 OAI97355.1 - 0.0027 18.0 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 OAI97355.1 - 0.019 15.4 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 OAI97355.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain TraI_2_C PF07515.11 OAI97361.1 - 3.2e-46 156.2 0.0 4.8e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Putative conjugal transfer nickase/helicase TraI C-term PMT_2 PF13231.6 OAI97361.1 - 3.5e-16 59.8 15.7 3.5e-16 59.8 15.7 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 OAI97361.1 - 3.7e-10 39.8 14.7 3.7e-10 39.8 14.7 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RP-C_C PF11800.8 OAI97369.1 - 3.1e-79 265.9 0.0 5.2e-79 265.1 0.0 1.4 1 0 0 1 1 1 1 Replication protein C C-terminal region RP-C PF03428.13 OAI97369.1 - 1.4e-69 233.2 2.2 2.7e-69 232.3 2.2 1.5 1 0 0 1 1 1 1 Replication protein C N-terminal domain HTH_20 PF12840.7 OAI97369.1 - 5.8e-05 23.1 0.4 0.003 17.6 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 OAI97369.1 - 0.00037 20.3 0.7 0.002 18.0 0.2 2.5 2 0 0 2 2 2 1 MarR family MarR PF01047.22 OAI97369.1 - 0.0039 17.1 0.3 0.057 13.4 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 OAI97369.1 - 0.0061 16.4 0.5 0.038 13.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 OAI97369.1 - 0.07 13.0 2.0 0.61 9.9 2.0 2.4 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 OAI97369.1 - 0.092 12.3 0.4 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TPR_14 PF13428.6 OAI97369.1 - 1.1 10.2 9.7 3.8 8.6 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAI97369.1 - 2.8 8.8 4.3 6.2 7.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Histone PF00125.24 OAI97372.1 - 2.2e-47 160.7 2.5 2.4e-47 160.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAI97372.1 - 6e-05 23.4 0.0 9.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAI97372.1 - 0.00016 21.7 0.1 0.00027 21.0 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OAI97372.1 - 0.0086 16.7 0.9 0.01 16.4 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 OAI97372.1 - 0.025 14.9 1.1 0.029 14.7 0.2 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HisKA PF00512.25 OAI97372.1 - 0.097 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Mucin PF01456.17 OAI97374.1 - 9.5e-05 22.4 17.3 0.00018 21.5 15.4 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Peptidase_S24 PF00717.23 OAI97374.1 - 0.088 12.8 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase S24-like Abhydrolase_1 PF00561.20 OAI97379.1 - 1.2e-20 74.3 0.1 1.6e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAI97379.1 - 2.1e-12 48.1 6.1 3.5e-12 47.4 6.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAI97379.1 - 3.3e-10 39.6 0.4 6.6e-10 38.7 0.4 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 OAI97379.1 - 0.066 13.6 0.2 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Asp PF00026.23 OAI97381.1 - 1.2e-52 179.3 0.5 1.6e-52 178.9 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OAI97381.1 - 0.00025 20.8 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 OAI97382.1 - 8.4e-05 22.1 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Cdd1 PF11731.8 OAI97389.1 - 0.19 12.0 0.0 2.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Pathogenicity locus DDE_Tnp_4 PF13359.6 OAI97392.1 - 1.4e-23 83.3 0.0 2.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAI97392.1 - 9.1e-06 25.4 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAI97392.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAI97392.1 - 0.027 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain RT_RNaseH_2 PF17919.1 OAI97396.1 - 1.2e-23 83.0 0.1 1.1e-14 54.3 0.1 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI97396.1 - 2.7e-17 63.0 0.0 1.6e-11 44.4 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI97396.1 - 1.2e-14 54.1 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI97396.1 - 1.1e-12 48.2 0.0 2.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain IPPT PF01715.17 OAI97398.1 - 4.3e-37 128.1 1.1 3.2e-35 122.0 0.1 2.9 2 1 0 2 2 2 1 IPP transferase DctP PF03480.13 OAI97398.1 - 0.16 11.3 0.4 0.36 10.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 SMI1_KNR4 PF09346.10 OAI97403.1 - 1e-20 74.5 0.0 1.9e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CENP-Q PF13094.6 OAI97406.1 - 0.00014 22.2 1.1 0.00022 21.5 1.1 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Tup_N PF08581.10 OAI97406.1 - 0.001 19.3 3.5 0.0017 18.6 3.5 1.3 1 0 0 1 1 1 1 Tup N-terminal SOAR PF16533.5 OAI97406.1 - 0.0035 17.3 2.7 0.0055 16.6 2.7 1.3 1 0 0 1 1 1 1 STIM1 Orai1-activating region PV-1 PF06637.11 OAI97406.1 - 0.013 14.4 1.3 0.016 14.1 1.3 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) MscS_porin PF12795.7 OAI97406.1 - 0.02 14.4 6.7 0.2 11.2 6.5 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DivIVA PF05103.13 OAI97406.1 - 0.086 12.9 5.1 0.14 12.2 5.1 1.3 1 0 0 1 1 1 0 DivIVA protein Phage_Mu_Gam PF07352.12 OAI97406.1 - 0.087 12.7 3.3 0.35 10.8 1.6 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein RNR_Alpha PF17975.1 OAI97406.1 - 0.11 13.0 0.2 0.23 12.0 0.1 1.6 1 1 1 2 2 2 0 Ribonucleotide reductase alpha domain Sua5_yciO_yrdC PF01300.18 OAI97412.1 - 7.9e-47 159.1 0.0 4.2e-45 153.4 0.0 2.5 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OAI97412.1 - 9.7e-28 97.4 0.0 4.5e-27 95.2 0.0 2.0 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding AA_permease_2 PF13520.6 OAI97414.1 - 2.7e-57 194.5 50.0 3.4e-57 194.2 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAI97414.1 - 4.6e-09 35.4 49.3 1e-08 34.3 49.3 1.5 1 1 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 OAI97416.1 - 1.3e-155 518.4 0.4 1.5e-155 518.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 OAI97426.1 - 3.1e-10 40.1 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAI97426.1 - 0.0014 18.7 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 OAI97430.1 - 9.2e-23 80.9 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97430.1 - 2.2e-11 43.5 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAI97430.1 - 4.7e-08 32.2 1.4 4.8e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Dimer_Tnp_hAT PF05699.14 OAI97432.1 - 1.5e-22 79.1 0.0 3.7e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAI97432.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4413 PF14372.6 OAI97432.1 - 0.031 14.6 0.0 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Herpes_BLLF1 PF05109.13 OAI97439.1 - 0.035 12.1 7.4 0.042 11.8 7.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) MREG PF15812.5 OAI97442.1 - 0.18 12.1 0.8 0.34 11.2 0.8 1.4 1 0 0 1 1 1 0 Melanoregulin DUF1178 PF06676.11 OAI97442.1 - 4 7.8 6.6 0.95 9.8 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) ACT_6 PF13740.6 OAI97446.1 - 0.16 12.0 0.2 27 4.8 0.0 2.5 2 0 0 2 2 2 0 ACT domain HsbA PF12296.8 OAI97450.1 - 3.1e-18 66.3 16.7 3.1e-18 66.3 16.7 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1307 PF06998.11 OAI97450.1 - 0.051 13.6 1.3 0.09 12.8 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1307) Carbpep_Y_N PF05388.11 OAI97450.1 - 0.22 12.1 4.0 0.25 11.9 0.7 2.1 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide ATP-synt_G PF04718.15 OAI97453.1 - 3.4e-16 59.9 2.1 6e-16 59.1 0.1 2.1 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit Utp12 PF04003.12 OAI97454.1 - 9.2e-19 67.7 0.6 1.4e-18 67.2 0.6 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 OAI97454.1 - 6.1e-05 23.7 1.4 0.00072 20.3 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat SPATA24 PF15175.6 OAI97458.1 - 0.056 13.3 3.5 0.15 12.0 0.5 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 DUF3619 PF12279.8 OAI97459.1 - 0.048 14.0 0.2 0.053 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Cnd2 PF05786.14 OAI97459.1 - 0.068 11.8 2.4 0.077 11.6 2.4 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Spt5_N PF11942.8 OAI97464.1 - 1.2e-18 67.9 11.5 1.2e-18 67.9 11.5 4.0 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 OAI97464.1 - 1.5e-15 56.9 0.0 3.5e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OAI97464.1 - 8.8e-07 28.7 7.1 0.00048 20.0 0.3 2.7 2 0 0 2 2 2 2 KOW motif Hexapep PF00132.24 OAI97464.1 - 0.038 13.7 0.0 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Chordopox_G2 PF05796.12 OAI97464.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus protein G2 Peptidase_M43 PF05572.13 OAI97471.1 - 7.6e-19 68.1 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAI97471.1 - 0.00023 21.7 1.1 0.0037 17.8 1.1 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAI97471.1 - 0.0012 19.0 0.5 0.0017 18.6 0.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAI97471.1 - 0.0015 18.2 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAI97471.1 - 0.003 17.4 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.16 OAI97471.1 - 0.036 14.2 0.6 0.087 12.9 0.6 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 OAI97471.1 - 0.1 11.8 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Asp_protease_2 PF13650.6 OAI97474.1 - 0.00098 19.7 0.0 0.0023 18.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 OAI97474.1 - 0.0068 16.7 1.6 0.015 15.5 1.6 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 OAI97474.1 - 0.025 15.1 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI97474.1 - 0.069 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_2 PF07727.14 OAI97482.1 - 1.3e-60 205.0 0.0 1.7e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI97482.1 - 0.02 14.7 3.3 0.036 13.9 1.5 2.3 2 1 0 2 2 2 0 Reverse transcriptase-like Crr6 PF08847.11 OAI97482.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.6 1 1 0 1 1 1 0 Chlororespiratory reduction 6 Pyridox_ox_2 PF12900.7 OAI97492.1 - 5.7e-36 123.6 0.0 7.5e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Helicase_C PF00271.31 OAI97493.1 - 6.3e-22 78.0 0.2 1.3e-21 77.0 0.1 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain fragilysinNterm PF16376.5 OAI97493.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of fragilysin tRNA-synt_1b PF00579.25 OAI97493.1 - 0.054 12.8 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PAAR_motif PF05488.13 OAI97499.1 - 0.00029 20.9 3.5 0.00097 19.3 3.4 1.8 1 1 0 1 1 1 1 PAAR motif FixS PF03597.15 OAI97500.1 - 0.078 12.7 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type TPR_2 PF07719.17 OAI97507.1 - 0.11 12.6 0.4 16 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAI97507.1 - 0.15 12.3 5.2 20 5.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAI97507.1 - 0.17 11.2 4.1 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 MalT-like TPR region Fer2 PF00111.27 OAI97513.1 - 0.009 16.0 2.9 0.014 15.3 2.9 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FYVE PF01363.21 OAI97513.1 - 0.05 13.7 2.3 0.076 13.2 2.3 1.3 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 OAI97513.1 - 0.19 12.0 5.1 0.42 10.9 5.1 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DDE_Tnp_4 PF13359.6 OAI97523.1 - 8.5e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyocin_S PF06958.12 OAI97528.1 - 1.1 9.7 5.6 4.2 7.9 0.5 2.1 2 0 0 2 2 2 0 S-type Pyocin MFS_1 PF07690.16 OAI97535.1 - 0.018 14.0 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3435 PF11917.8 OAI97535.1 - 0.2 10.5 2.6 0.23 10.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3435) zf-CCHC PF00098.23 OAI97540.1 - 0.011 15.8 5.4 0.021 14.9 5.4 1.4 1 0 0 1 1 1 0 Zinc knuckle TTRAP PF14203.6 OAI97540.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein zf-CCHC_3 PF13917.6 OAI97540.1 - 0.045 13.7 0.7 0.1 12.6 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle V-ATPase_G_2 PF16999.5 OAI97540.1 - 1 9.8 4.1 0.93 9.9 1.9 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF3136 PF11334.8 OAI97551.1 - 0.036 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Mpp10 PF04006.12 OAI97570.1 - 9.3e-05 21.1 28.2 9.3e-05 21.1 28.2 2.7 1 1 1 2 2 2 1 Mpp10 protein Herpes_BLLF1 PF05109.13 OAI97572.1 - 0.51 8.2 13.4 1.1 7.1 13.4 1.4 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DNA_pol_viral_C PF00336.18 OAI97587.1 - 0.067 12.6 0.0 0.21 11.0 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAI97587.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like LAP1C PF05609.12 OAI97592.1 - 4.4 6.3 15.3 5.6 5.9 15.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF5094 PF17015.5 OAI97592.1 - 8 6.5 8.2 13 5.9 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DDE_Tnp_4 PF13359.6 OAI97593.1 - 1.4e-19 70.3 0.0 3.6e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DNA_pol_viral_C PF00336.18 OAI97595.1 - 0.013 14.9 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain ANAPC4_WD40 PF12894.7 OAI97597.1 - 0.037 14.3 0.0 0.2 12.0 0.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain MitoNEET_N PF10660.9 OAI97602.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus RVT_1 PF00078.27 OAI97609.1 - 2.6e-17 63.1 0.0 3.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 OAI97612.1 - 2e-45 154.7 1.2 2.8e-45 154.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAI97612.1 - 3.3e-28 98.8 1.3 4.4e-28 98.4 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAI97612.1 - 2.7e-05 23.7 0.1 5.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAI97612.1 - 0.00014 21.8 0.2 0.00035 20.5 0.2 1.7 1 1 0 1 1 1 1 KR domain SR-25 PF10500.9 OAI97613.1 - 2.7 7.6 40.8 0.22 11.1 15.1 2.1 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein IFRD_C PF04836.12 OAI97621.1 - 0.027 15.1 0.0 0.087 13.4 0.0 2.0 1 0 0 1 1 1 0 Interferon-related protein conserved region DUF148 PF02520.17 OAI97624.1 - 0.051 13.7 3.5 0.085 13.0 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF148 Presenilin PF01080.17 OAI97625.1 - 2.9 6.6 3.3 2.4 6.8 3.3 1.2 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 OAI97625.1 - 3.7 7.1 24.6 5.9 6.4 24.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 OAI97625.1 - 4.5 7.6 29.0 8.2 6.7 29.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) EspB_PE PF18625.1 OAI97629.1 - 0.00014 22.2 1.6 0.0002 21.7 1.6 1.2 1 0 0 1 1 1 1 ESX-1 secreted protein B PE domain DUF1542 PF07564.11 OAI97629.1 - 0.016 15.3 0.7 0.022 14.8 0.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Herpes_TK PF00693.18 OAI97629.1 - 0.083 12.1 0.0 0.088 12.0 0.0 1.0 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DPM2 PF07297.12 OAI97638.1 - 4e-28 97.5 0.2 4.6e-28 97.3 0.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OAI97638.1 - 2.1e-05 24.4 0.1 2.5e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 OAI97638.1 - 0.034 14.2 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4083 PF13314.6 OAI97638.1 - 0.14 12.1 0.3 2 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DJ-1_PfpI PF01965.24 OAI97639.1 - 7.6e-38 129.9 0.1 8.8e-38 129.7 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family MtmB PF05369.12 OAI97639.1 - 0.016 14.1 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB LppA PF16708.5 OAI97653.1 - 0.058 13.3 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium Peptidase_M16 PF00675.20 OAI97658.1 - 2e-23 83.0 0.0 2.4e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAI97658.1 - 3.1e-07 30.6 0.1 1.2e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain TAL_FSA PF00923.19 OAI97658.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Nudix_N PF12535.8 OAI97658.1 - 0.074 12.7 0.4 0.47 10.1 0.1 2.2 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal TetR PF13972.6 OAI97659.1 - 0.00062 19.5 0.0 0.00069 19.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial transcriptional repressor HlyD_3 PF13437.6 OAI97660.1 - 2.2e-17 63.7 0.2 1.1e-12 48.6 0.0 3.5 2 2 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 OAI97660.1 - 3e-12 46.1 0.1 7.2e-05 22.5 0.0 3.1 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 OAI97660.1 - 4.4e-08 32.6 3.6 9.6e-05 21.7 1.3 2.4 1 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 OAI97660.1 - 8.4e-06 25.5 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.20 OAI97660.1 - 6.9e-05 22.7 4.6 0.00011 22.0 4.6 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Peptidase_M23 PF01551.22 OAI97660.1 - 0.0069 16.6 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 Peptidase family M23 Lyase_aromatic PF00221.19 OAI97663.1 - 2.9e-06 26.3 2.8 0.0021 16.8 1.3 3.0 2 1 1 3 3 3 3 Aromatic amino acid lyase TrpP PF17099.5 OAI97663.1 - 0.031 14.1 0.1 0.1 12.4 0.1 1.6 1 1 1 2 2 2 0 Tryptophan transporter TrpP YL1 PF05764.13 OAI97668.1 - 0.03 14.4 15.1 0.036 14.2 15.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 OAI97668.1 - 0.26 9.8 20.3 0.35 9.4 20.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 OAI97668.1 - 1.4 7.1 10.5 1.6 6.9 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAI97668.1 - 4.9 5.6 5.3 5.1 5.5 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Exo_endo_phos PF03372.23 OAI97671.1 - 6.2e-15 55.4 0.0 9.2e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RT_RNaseH_2 PF17919.1 OAI97676.1 - 5.9e-15 55.1 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI97676.1 - 1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAI97676.1 - 1.7e-06 28.0 0.1 3.5e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAI97676.1 - 0.0038 17.5 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Herpes_ORF11 PF04797.13 OAI97677.1 - 0.0003 19.7 0.0 0.00045 19.1 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Asp_protease_2 PF13650.6 OAI97677.1 - 0.014 16.0 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 OAI97677.1 - 0.14 12.7 0.0 0.72 10.5 0.0 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Amelogenin PF02948.15 OAI97681.1 - 0.17 12.5 0.3 17 6.0 0.0 2.1 2 0 0 2 2 2 0 Amelogenin DUF1768 PF08719.11 OAI97684.1 - 1.7e-18 67.4 0.1 1.9e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1729 PF08354.10 OAI97685.1 - 5.4e-109 364.3 0.1 7.6e-109 363.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) SAT PF16073.5 OAI97685.1 - 5.8e-29 101.5 0.0 7.9e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Membr_traf_MHD PF10540.9 OAI97696.1 - 4e-15 56.3 0.5 9.7e-08 32.3 0.7 2.5 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAI97696.1 - 5.1e-08 33.2 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Glyco_hydro_cc PF11790.8 OAI97702.1 - 2.2e-54 184.6 0.8 2.5e-54 184.4 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SurE PF01975.17 OAI97711.1 - 4e-39 134.4 0.0 6.8e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE Transthyretin PF00576.21 OAI97716.1 - 2.6e-33 115.0 0.0 1.3e-32 112.7 0.0 1.8 1 1 0 1 1 1 1 HIUase/Transthyretin family COG5 PF10392.9 OAI97717.1 - 3.3e-10 40.2 2.4 4.1e-10 39.9 1.4 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 OmpW PF03922.14 OAI97722.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 OmpW family ELP6 PF09807.9 OAI97728.1 - 3e-08 33.4 0.0 4.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 NACHT PF05729.12 OAI97728.1 - 0.0045 16.9 0.1 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Herpes_UL14 PF03580.14 OAI97736.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.6 2 2 1 4 4 4 0 Herpesvirus UL14-like protein Helicase_C PF00271.31 OAI97742.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peripla_BP_4 PF13407.6 OAI97742.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF3437 PF11919.8 OAI97748.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) RVT_1 PF00078.27 OAI97750.1 - 3.3e-22 79.1 0.0 5.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI97750.1 - 1.1e-14 54.3 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI97750.1 - 0.0055 17.0 0.0 0.0099 16.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GMC_oxred_N PF00732.19 OAI97754.1 - 4.2e-49 167.5 0.0 5.5e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAI97754.1 - 1.4e-05 24.6 0.1 0.015 14.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAI97754.1 - 6.1e-05 23.2 0.1 0.00017 21.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAI97754.1 - 6.3e-05 22.2 0.1 0.0019 17.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAI97754.1 - 0.0002 21.0 0.2 0.0026 17.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAI97754.1 - 0.00048 19.3 0.1 0.00069 18.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAI97754.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAI97754.1 - 0.023 13.9 0.1 0.052 12.8 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LapA_dom PF06305.11 OAI97759.1 - 0.19 11.6 0.5 0.35 10.7 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF1180 PF06679.12 OAI97759.1 - 9.3 6.6 12.0 0.28 11.6 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sec61_beta PF03911.16 OAI97762.1 - 4.5e-17 61.8 0.7 6e-17 61.4 0.7 1.2 1 0 0 1 1 1 1 Sec61beta family DUF2316 PF10078.9 OAI97764.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) PBP1_TM PF14812.6 OAI97768.1 - 0.013 15.9 23.8 0.018 15.4 5.7 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal pP_pnuc_2 PF18166.1 OAI97768.1 - 0.16 12.0 1.9 0.27 11.3 1.9 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease G_path_suppress PF15991.5 OAI97768.1 - 0.38 10.8 16.6 0.56 10.3 16.6 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Myc_N PF01056.18 OAI97768.1 - 0.64 9.9 15.8 0.036 14.0 8.2 2.1 1 1 1 2 2 2 0 Myc amino-terminal region FliD_N PF02465.18 OAI97768.1 - 0.73 10.6 0.1 0.73 10.6 0.1 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spt20 PF12090.8 OAI97768.1 - 3 7.4 14.1 1.4 8.4 6.4 2.2 2 0 0 2 2 2 0 Spt20 family RAP1 PF07218.11 OAI97768.1 - 4.5 5.4 10.2 6.3 5.0 10.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TipE PF16972.5 OAI97768.1 - 6.9 5.7 13.0 2.4 7.3 9.8 1.7 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE Sigma70_ner PF04546.13 OAI97768.1 - 9.8 6.0 12.3 1.8 8.4 4.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region CM_2 PF01817.21 OAI97769.1 - 0.00014 22.1 0.0 0.055 13.8 0.0 2.6 2 0 0 2 2 2 2 Chorismate mutase type II PMT PF02366.18 OAI97772.1 - 3.4e-14 53.0 3.2 4.5e-14 52.6 3.2 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pkinase PF00069.25 OAI97776.1 - 1.4e-37 129.5 0.0 4.5e-37 127.8 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97776.1 - 6.1e-22 78.2 0.0 1.6e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase BST2 PF16716.5 OAI97776.1 - 0.021 15.4 9.0 0.021 15.4 9.0 5.3 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 OAI97776.1 - 0.035 14.5 0.6 0.035 14.5 0.6 4.8 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF2935 PF11155.8 OAI97776.1 - 0.096 13.0 9.5 1.6 9.1 2.6 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF2935) Tropomyosin PF00261.20 OAI97776.1 - 0.11 11.8 59.8 0.17 11.2 50.8 3.9 1 1 1 2 2 2 0 Tropomyosin GAS PF13851.6 OAI97776.1 - 0.26 10.6 55.1 0.02 14.3 12.2 4.7 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding APH PF01636.23 OAI97776.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.4 2 2 0 3 3 2 0 Phosphotransferase enzyme family Cep57_CLD PF14073.6 OAI97776.1 - 1.2 9.2 58.5 0.13 12.3 18.3 3.1 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 Spc7 PF08317.11 OAI97776.1 - 2.8 6.7 60.5 0.55 9.1 18.3 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 OAI97776.1 - 4.5 7.4 59.2 0.16 12.1 22.3 3.9 2 1 2 4 4 3 0 Tropomyosin like Mo25 PF08569.11 OAI97781.1 - 1.1e-128 429.3 0.0 2.3e-128 428.2 0.0 1.5 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 OAI97781.1 - 0.039 14.4 0.0 0.68 10.4 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats Tfb5 PF06331.12 OAI97784.1 - 8.3e-27 93.0 0.2 9e-27 92.9 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Pyr_redox_2 PF07992.14 OAI97785.1 - 0.0036 16.6 0.0 0.0095 15.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 OAI97788.1 - 4.4e-12 45.7 0.2 4.4e-12 45.7 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAI97788.1 - 3.6e-08 33.1 0.2 1.2e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain PQQ PF01011.21 OAI97788.1 - 0.0013 18.5 2.0 0.011 15.7 0.2 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 OAI97788.1 - 0.018 14.6 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 OAI97788.1 - 0.029 14.9 0.1 7.5 7.2 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain F-box_4 PF15966.5 OAI97788.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 F-box Abhydrolase_6 PF12697.7 OAI97794.1 - 0.0033 18.1 0.1 0.006 17.2 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.22 OAI97797.1 - 4.8e-40 137.7 0.0 1.3e-39 136.3 0.0 1.7 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAI97797.1 - 1e-12 48.7 0.0 2.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAI97797.1 - 0.00071 19.6 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF883 PF05957.13 OAI97800.1 - 0.092 13.4 0.3 0.14 12.7 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Nbl1_Borealin_N PF10444.9 OAI97800.1 - 0.24 11.1 2.0 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal ABC_tran PF00005.27 OAI97805.1 - 1.6e-16 61.1 0.0 7.6e-16 58.9 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAI97805.1 - 7.7e-11 42.3 1.0 0.00026 20.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAI97805.1 - 0.00048 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAI97805.1 - 0.0055 16.3 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 OAI97805.1 - 0.0059 16.1 0.2 2.2 7.7 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OAI97805.1 - 0.0079 16.4 0.1 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OAI97805.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OAI97805.1 - 0.017 15.2 0.1 0.04 14.0 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAI97805.1 - 0.03 14.7 0.1 0.055 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 OAI97805.1 - 0.04 13.4 0.1 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_23 PF13476.6 OAI97805.1 - 0.047 14.2 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAI97805.1 - 0.055 13.2 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 OAI97805.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 OAI97805.1 - 0.079 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAI97805.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 OAI97805.1 - 0.1 12.3 0.2 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAI97805.1 - 0.18 12.2 0.2 1.9 8.9 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pantoate_transf PF02548.15 OAI97808.1 - 7.7e-89 297.5 1.9 1.8e-84 283.2 0.5 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAI97808.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.4 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase RNase_H PF00075.24 OAI97812.1 - 6.6e-12 45.8 0.0 1.6e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAI97812.1 - 2.8e-07 30.4 0.1 1.1e-06 28.5 0.1 2.1 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.27 OAI97812.1 - 0.00062 19.3 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIF_2_alpha PF07541.12 OAI97816.1 - 1.3e-35 122.0 0.0 2.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAI97816.1 - 8.4e-14 51.7 0.2 1.9e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain NIL PF09383.10 OAI97816.1 - 0.019 14.8 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 NIL domain Amidohydro_1 PF01979.20 OAI97816.1 - 0.049 13.0 0.1 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase family Histone PF00125.24 OAI97817.1 - 1e-38 132.6 1.6 1.2e-38 132.5 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAI97817.1 - 2.7e-05 24.5 0.0 3.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAI97817.1 - 4.5e-05 23.5 0.1 5.3e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAI97817.1 - 0.013 15.8 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DDE_1 PF03184.19 OAI97827.1 - 2.5e-17 63.1 0.0 4.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAI97827.1 - 2.3e-09 37.1 0.0 8.1e-09 35.4 0.0 2.0 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAI97827.1 - 0.0058 16.3 0.1 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Histone_HNS PF00816.21 OAI97827.1 - 0.068 14.0 0.1 6.7 7.6 0.2 2.4 2 0 0 2 2 2 0 H-NS histone family Ribonuclease_3 PF00636.26 OAI97830.1 - 3.8e-15 56.4 0.1 2.1e-14 54.0 0.0 2.4 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAI97830.1 - 0.00018 21.7 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease-III-like Presenilin PF01080.17 OAI97830.1 - 0.91 8.2 7.2 0.3 9.8 3.4 1.9 2 0 0 2 2 2 0 Presenilin FHA PF00498.26 OAI97842.1 - 0.041 14.2 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 FHA domain DUF1543 PF07566.12 OAI97842.1 - 0.26 11.1 0.4 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) Sec3_C PF09763.9 OAI97844.1 - 0.018 13.5 4.1 0.029 12.8 4.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4335 PF14233.6 OAI97844.1 - 0.033 14.1 3.7 0.058 13.3 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF3496 PF12001.8 OAI97844.1 - 0.15 12.4 2.0 0.26 11.7 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) T6PP_N PF18572.1 OAI97844.1 - 0.54 10.1 4.3 11 5.9 0.4 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain LTXXQ PF07813.12 OAI97844.1 - 2.5 8.9 14.8 0.83 10.4 1.7 3.4 3 0 0 3 3 3 0 LTXXQ motif family protein Helicase_C PF00271.31 OAI97848.1 - 1.1e-09 38.6 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PUB_1 PF18486.1 OAI97848.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain GTPase_binding PF09027.10 OAI97851.1 - 0.064 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 GTPase binding Spt5_N PF11942.8 OAI97851.1 - 0.46 11.5 6.9 0.87 10.6 4.4 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CBFB_NFYA PF02045.15 OAI97852.1 - 2.6e-17 63.2 27.1 6e-12 46.0 2.2 3.6 3 1 0 3 3 3 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Abhydrolase_6 PF12697.7 OAI97861.1 - 0.00069 20.3 0.0 0.001 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.28 OAI97861.1 - 0.039 14.5 0.1 0.37 11.2 0.0 2.3 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase SOG2 PF10428.9 OAI97875.1 - 0.52 9.5 29.7 0.67 9.1 29.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FixO PF02433.15 OAI97879.1 - 0.037 13.5 1.8 0.043 13.3 1.8 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Atg14 PF10186.9 OAI97879.1 - 0.59 9.2 3.9 0.64 9.1 3.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMWPc PF01451.21 OAI97886.1 - 4.8e-37 127.5 0.0 5.5e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sgf11 PF08209.11 OAI97887.1 - 3.6e-13 48.8 0.7 3.6e-13 48.8 0.7 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 OAI97887.1 - 0.12 12.3 1.4 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3446 PF11928.8 OAI97887.1 - 4.4 7.7 13.2 14 6.1 0.9 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain RsfS PF02410.15 OAI97891.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation V-ATPase_G PF03179.15 OAI97897.1 - 3.4e-33 114.3 18.2 4e-33 114.1 18.2 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 OAI97897.1 - 0.03 14.4 11.7 0.03 14.4 11.7 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) TFA2_Winged_2 PF18121.1 OAI97897.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Halogen_Hydrol PF10112.9 OAI97897.1 - 0.15 12.0 7.6 0.22 11.5 6.6 1.7 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ntox34 PF15606.6 OAI97897.1 - 0.18 12.0 1.9 0.29 11.3 0.4 2.0 2 1 1 3 3 3 0 Bacterial toxin 34 PTPlike_phytase PF14566.6 OAI97897.1 - 0.19 11.9 3.7 0.22 11.6 3.7 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate OmpH PF03938.14 OAI97897.1 - 0.71 10.2 17.3 0.96 9.8 17.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 OAI97897.1 - 2.6 8.3 13.9 9.3 6.5 13.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 OAI97897.1 - 3.1 7.1 14.6 3.4 6.9 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 OAI97897.1 - 3.5 7.3 10.8 4.2 7.1 10.8 1.1 1 0 0 1 1 1 0 AAA domain Lectin_N PF03954.14 OAI97897.1 - 4.5 7.0 6.5 2 8.2 3.8 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain cwf21 PF08312.12 OAI97898.1 - 0.19 11.9 0.4 0.25 11.5 0.4 1.1 1 0 0 1 1 1 0 cwf21 domain DUF2205 PF10224.9 OAI97899.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 OAI97899.1 - 0.0015 19.2 0.0 0.0018 18.9 0.0 1.1 1 0 0 1 1 1 1 Initiation control protein YabA TACC_C PF05010.14 OAI97899.1 - 0.0091 15.8 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RVT_1 PF00078.27 OAI97903.1 - 6e-14 52.1 0.0 8.9e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAI97903.1 - 0.016 14.8 3.0 0.078 12.5 3.0 2.1 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DNA_circ_N PF07157.12 OAI97907.1 - 0.018 15.4 0.3 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 DNA circularisation protein N-terminus zf-C2H2_10 PF16588.5 OAI97907.1 - 0.047 13.4 1.0 0.099 12.4 1.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Zf_RING PF16744.5 OAI97907.1 - 0.058 13.5 0.2 0.096 12.8 0.2 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger adh_short PF00106.25 OAI97919.1 - 2.9e-26 92.1 0.1 3.1e-17 62.7 0.3 3.0 2 2 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAI97919.1 - 8e-16 58.3 0.0 2.2e-14 53.6 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAI97919.1 - 4.3e-07 29.6 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAI97919.1 - 4.9e-06 26.6 0.0 9.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAI97919.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) CDC45 PF02724.14 OAI97920.1 - 0.088 11.1 8.5 0.13 10.6 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BBP1_N PF15271.6 OAI97920.1 - 0.92 10.3 10.3 0.25 12.1 2.8 2.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein TFIIA PF03153.13 OAI97920.1 - 7.9 6.4 27.5 11 5.9 27.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Actin PF00022.19 OAI97923.1 - 1.1e-73 248.3 0.0 2.3e-72 243.9 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OAI97923.1 - 0.13 12.7 0.1 0.39 11.2 0.0 2.0 2 1 0 2 2 2 0 Cell division protein FtsA baeRF_family10 PF18854.1 OAI97923.1 - 0.17 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 MULE PF10551.9 OAI97931.1 - 3.2e-20 72.3 0.9 8.8e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OAI97931.1 - 2.7e-07 30.5 1.4 3.6e-07 30.1 0.3 1.7 2 0 0 2 2 2 1 MuDR family transposase Transposase_mut PF00872.18 OAI97931.1 - 7e-06 25.1 0.0 1.4e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Transposase, Mutator family WH1 PF00568.23 OAI97931.1 - 0.1 12.5 0.2 0.28 11.1 0.2 1.7 2 0 0 2 2 2 0 WH1 domain Ribosomal_S7e PF01251.18 OAI97931.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e Tim17 PF02466.19 OAI97936.1 - 9.4e-09 35.6 10.4 1.5e-08 35.0 10.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 OAI97937.1 - 8.6e-65 214.7 5.0 2.3e-24 85.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 OAI97937.1 - 0.16 11.1 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Fuseless Asp_protease_2 PF13650.6 OAI97946.1 - 0.00027 21.5 0.3 0.0011 19.6 0.1 2.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI97946.1 - 0.00081 19.9 0.0 0.0047 17.5 0.0 2.2 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI97946.1 - 0.14 12.5 0.1 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 Retroviral aspartyl protease Histone PF00125.24 OAI97949.1 - 2.8e-29 102.1 0.4 3.1e-29 102.0 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OAI97949.1 - 0.0048 17.5 1.4 0.006 17.2 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain BON PF04972.17 OAI97949.1 - 0.044 14.1 0.1 0.097 13.0 0.1 1.6 1 0 0 1 1 1 0 BON domain STI1 PF17830.1 OAI97950.1 - 4.2e-08 33.0 0.0 6.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 STI1 domain Mto2_bdg PF12808.7 OAI97959.1 - 0.0045 17.3 0.0 0.0063 16.8 0.0 1.2 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region BBP1_C PF15272.6 OAI97959.1 - 0.0047 16.8 0.1 0.0056 16.5 0.1 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal BRE1 PF08647.11 OAI97959.1 - 0.035 14.2 0.3 0.04 14.0 0.3 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Sec2p PF06428.11 OAI97959.1 - 0.048 13.6 0.3 0.058 13.4 0.3 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pet20 PF08692.10 OAI97964.1 - 2 9.1 18.5 1.8e+04 -4.1 18.5 2.6 1 1 0 1 1 1 0 Mitochondrial protein Pet20 CRT10 PF08728.10 OAI97964.1 - 5.5 5.0 19.8 9 4.3 19.8 1.3 1 0 0 1 1 1 0 CRT10 AF-4 PF05110.13 OAI97964.1 - 5.9 4.8 51.0 8.1 4.4 51.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_hydro_88 PF07470.13 OAI97971.1 - 1.1e-15 57.6 2.4 2.7e-15 56.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Biotin_lipoyl_2 PF13533.6 OAI97975.1 - 5.2e-11 42.2 3.0 7.9e-11 41.6 2.6 1.5 1 1 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 OAI97975.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme PGAP1 PF07819.13 OAI97976.1 - 1.5e-05 24.8 0.1 4.2e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAI97976.1 - 1.9e-05 25.4 1.6 5.2e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OAI97976.1 - 8.7e-05 22.4 0.0 0.069 12.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF676 PF05057.14 OAI97976.1 - 0.0019 17.8 0.1 0.0075 15.8 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.12 OAI97976.1 - 0.0066 16.4 0.1 0.055 13.4 0.0 2.2 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 OAI97976.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 OAI97976.1 - 0.013 15.1 0.1 0.6 9.7 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAI97976.1 - 0.057 12.7 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 OAI97976.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region TetR_N PF00440.23 OAI97977.1 - 1.5e-09 37.5 0.1 2.8e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 OAI97977.1 - 7.1e-06 26.7 2.0 7.1e-06 26.7 2.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DDE_Tnp_4 PF13359.6 OAI97979.1 - 1.4e-23 83.3 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAI97979.1 - 1.3e-05 24.9 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain ACC_epsilon PF13822.6 OAI97980.1 - 7.5 7.3 12.6 0.63 10.8 7.3 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.25 OAI97986.1 - 7.3e-21 74.7 0.0 1.6e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97986.1 - 2.9e-11 43.2 0.0 4.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAI97986.1 - 5e-08 32.6 0.0 9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OAI97986.1 - 0.046 12.7 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAI97986.1 - 0.063 12.6 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LIP PF03583.14 OAI97999.1 - 4.1e-19 69.0 0.0 4.9e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAI97999.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAI97999.1 - 0.0096 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cys_Met_Meta_PP PF01053.20 OAI98003.1 - 7e-131 436.3 0.0 1.2e-130 435.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OAI98003.1 - 2.1e-05 23.3 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OAI98003.1 - 5.2e-05 22.4 0.0 7.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAI98003.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Alliinase_C PF04864.13 OAI98003.1 - 0.017 14.0 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Allinase zf-CCHC PF00098.23 OAI98008.1 - 0.0052 16.8 2.0 0.0092 16.0 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 OAI98008.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF373 PF04123.13 OAI98012.1 - 5.8 6.3 13.5 3.3 7.0 2.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF373) RVT_1 PF00078.27 OAI98015.1 - 2.7e-26 92.5 0.0 4.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAAT_C PF08840.11 OAI98015.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Septin PF00735.18 OAI98018.1 - 0.024 13.9 0.0 0.028 13.7 0.0 1.0 1 0 0 1 1 1 0 Septin zf-CCHC PF00098.23 OAI98024.1 - 0.0053 16.8 2.0 0.0095 16.0 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle FANCF PF11107.8 OAI98024.1 - 0.0076 15.5 0.0 0.031 13.5 0.0 1.8 1 1 1 2 2 2 1 Fanconi anemia group F protein (FANCF) Asp_protease_2 PF13650.6 OAI98024.1 - 0.041 14.5 0.0 0.096 13.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 OAI98038.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ldh_1_C PF02866.18 OAI98043.1 - 7.7e-09 35.7 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ECH_1 PF00378.20 OAI98050.1 - 6.2e-18 65.0 0.0 8.7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAI98050.1 - 0.00012 21.7 0.1 0.00016 21.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4609 PF15382.6 OAI98053.1 - 0.12 12.2 0.0 0.53 10.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) rve PF00665.26 OAI98060.1 - 6.2e-13 49.0 0.0 9.6e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAI98060.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 OAI98065.1 - 1.3e-33 116.2 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAI98065.1 - 3.4e-05 24.1 2.1 0.0059 16.9 0.2 2.8 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAI98065.1 - 3.5e-05 23.8 0.0 0.00014 21.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAI98065.1 - 5.6e-05 23.6 0.2 0.0012 19.3 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAI98065.1 - 0.0014 18.8 0.1 0.0038 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAI98065.1 - 0.0016 18.2 0.3 0.011 15.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAI98065.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAI98065.1 - 0.036 14.6 1.3 0.1 13.1 0.0 2.3 2 2 0 2 2 2 0 AAA domain Beta_protein PF14350.6 OAI98065.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta protein RuvB_N PF05496.12 OAI98065.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 OAI98065.1 - 0.14 12.5 0.4 0.83 10.0 0.5 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAI98065.1 - 0.14 11.7 4.6 0.15 11.6 1.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAI98065.1 - 0.14 12.4 0.4 0.27 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Herpes_UL33 PF03581.13 OAI98065.1 - 0.16 12.4 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Asp PF00026.23 OAI98069.1 - 6.9e-52 176.8 5.6 1.2e-51 176.0 5.6 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAI98069.1 - 2.4e-07 31.1 1.0 0.02 15.1 0.1 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAI98069.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Transposase_21 PF02992.14 OAI98075.1 - 4.2e-08 32.7 0.0 7.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAI98075.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-UDP PF14569.6 OAI98075.1 - 0.27 11.4 1.3 0.55 10.4 1.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger KDZ PF18758.1 OAI98079.1 - 3.7e-46 157.5 0.0 6.1e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAI98079.1 - 8.1e-07 29.2 0.1 2.7e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAI98079.1 - 0.00015 21.9 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Fringe PF02434.16 OAI98088.1 - 2.6e-05 23.8 0.7 0.00025 20.6 0.5 2.3 2 1 0 2 2 2 1 Fringe-like 60KD_IMP PF02096.20 OAI98095.1 - 2.3e-24 86.1 0.4 3.3e-24 85.7 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Phasin_2 PF09361.10 OAI98095.1 - 1.5 9.2 14.7 0.34 11.2 10.5 2.1 2 0 0 2 2 2 0 Phasin protein DUF3306 PF11748.8 OAI98095.1 - 6.1 7.7 8.2 6.3 7.7 5.8 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Steroid_dh PF02544.16 OAI98115.1 - 1.6e-32 112.5 0.5 2.8e-32 111.8 0.5 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAI98115.1 - 2.1e-07 30.7 0.1 3.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 OAI98115.1 - 2.5e-06 27.1 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family ICMT PF04140.14 OAI98115.1 - 0.0013 19.1 0.2 0.0029 18.0 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAI98115.1 - 0.0031 17.9 0.9 0.012 16.0 0.4 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase DUF2986 PF11661.8 OAI98116.1 - 0.012 16.1 0.4 0.012 16.1 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2986) MFAP1 PF06991.11 OAI98116.1 - 0.016 15.1 3.3 0.029 14.2 3.3 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing TerB_C PF15615.6 OAI98116.1 - 2.7 8.3 7.2 1.1 9.5 2.6 2.1 2 0 0 2 2 2 0 TerB-C domain DUF1768 PF08719.11 OAI98121.1 - 8.1e-25 87.9 0.0 1.1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Mis14 PF08641.12 OAI98125.1 - 0.13 12.6 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Asp_protease_2 PF13650.6 OAI98126.1 - 6.9e-06 26.6 0.2 1.4e-05 25.7 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI98126.1 - 2.4e-05 24.8 0.1 7.9e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI98126.1 - 0.04 14.2 0.0 0.15 12.3 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1658 PF07871.11 OAI98126.1 - 0.39 10.7 2.9 3 8.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) P66_CC PF16563.5 OAI98127.1 - 0.18 11.5 1.5 0.3 10.7 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Synaptobrevin PF00957.21 OAI98131.1 - 1.8e-26 91.8 0.2 2.5e-26 91.3 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAI98131.1 - 2.1e-18 66.1 0.0 3.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Iso_dh PF00180.20 OAI98132.1 - 6.5e-91 305.1 0.0 1.3e-90 304.0 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMG_box PF00505.19 OAI98152.1 - 1.7e-20 73.2 0.7 1.7e-20 73.2 0.7 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAI98152.1 - 1.7e-12 47.7 0.6 1.7e-12 47.7 0.6 1.8 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 OAI98152.1 - 0.057 13.4 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 OAI98152.1 - 0.97 10.0 4.6 0.26 11.9 1.6 1.5 2 0 0 2 2 2 0 YABBY protein DUF2384 PF09722.10 OAI98159.1 - 0.0016 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) MFS_1 PF07690.16 OAI98163.1 - 3.1e-17 62.5 46.1 3.1e-17 62.5 46.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAI98163.1 - 3.4e-05 22.5 21.1 9e-05 21.1 21.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) REF PF05755.12 OAI98163.1 - 0.072 12.9 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF4811 PF16069.5 OAI98163.1 - 0.39 10.6 1.8 17 5.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) rve PF00665.26 OAI98169.1 - 3.8e-16 59.4 0.0 7.8e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAI98169.1 - 1.2e-11 44.5 0.0 2.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAI98169.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain GntR PF00392.21 OAI98169.1 - 0.033 13.8 0.2 1.4 8.7 0.2 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-CCHC PF00098.23 OAI98169.1 - 0.8 9.9 9.6 0.48 10.6 7.4 1.9 2 0 0 2 2 2 0 Zinc knuckle Thi4 PF01946.17 OAI98175.1 - 2e-47 161.4 0.0 2.5e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAI98175.1 - 1.5e-07 30.8 1.2 0.00021 20.5 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAI98175.1 - 2.7e-06 27.5 0.0 5.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAI98175.1 - 9.5e-06 25.4 0.1 1.2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAI98175.1 - 0.00018 20.9 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAI98175.1 - 0.00041 20.4 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAI98175.1 - 0.0047 16.1 0.3 0.011 14.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAI98175.1 - 0.03 13.0 0.1 0.039 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 OAI98175.1 - 0.078 11.8 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.15 OAI98175.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 OAI98175.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RHD3 PF05879.12 OAI98176.1 - 0.0042 15.3 0.0 0.0043 15.3 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Cactin_mid PF10312.9 OAI98179.1 - 1.9e-64 217.1 4.9 1.9e-64 217.1 4.9 2.4 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OAI98179.1 - 2.3e-56 189.1 6.5 4.1e-56 188.3 6.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Bac_DnaA PF00308.18 OAI98179.1 - 0.49 10.2 3.5 0.21 11.4 0.3 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Polysacc_deac_1 PF01522.21 OAI98184.1 - 3.2e-27 94.9 0.0 6.6e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 OAI98184.1 - 0.2 9.7 13.6 0.72 7.9 13.6 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Spc7 PF08317.11 OAI98188.1 - 0.0023 16.9 0.6 0.0023 16.9 0.6 3.0 2 1 1 3 3 3 2 Spc7 kinetochore protein APG6_N PF17675.1 OAI98188.1 - 0.0077 16.8 2.1 0.0077 16.8 2.1 4.1 2 2 1 3 3 3 1 Apg6 coiled-coil region Filament PF00038.21 OAI98188.1 - 0.018 14.6 20.5 0.094 12.3 5.0 3.7 2 2 1 3 3 3 0 Intermediate filament protein WEMBL PF05701.11 OAI98188.1 - 0.25 10.0 20.2 0.07 11.8 7.3 2.5 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Atg14 PF10186.9 OAI98188.1 - 2.4 7.2 16.5 0.78 8.8 4.3 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Trimer_CC PF08954.11 OAI98188.1 - 6 6.5 11.2 1.7 8.2 1.2 4.3 3 1 1 4 4 4 0 Trimerisation motif DivIC PF04977.15 OAI98188.1 - 7.4 6.4 18.1 0.048 13.4 1.1 4.0 3 1 3 6 6 6 0 Septum formation initiator ATG16 PF08614.11 OAI98188.1 - 8.3 6.6 31.0 0.46 10.7 4.8 3.4 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) RVT_1 PF00078.27 OAI98198.1 - 1.5e-16 60.6 0.0 2.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 OAI98201.1 - 3.7e-69 233.0 0.0 5.1e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3253 PF11625.8 OAI98201.1 - 3.2 8.1 4.7 1.1 9.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3253) SSXT PF05030.12 OAI98206.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Pkinase PF00069.25 OAI98211.1 - 2.7e-24 86.0 0.1 8.7e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI98211.1 - 2.6e-15 56.4 0.1 8.3e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Fez1 PF06818.15 OAI98211.1 - 0.55 10.7 42.6 0.5 10.8 3.8 3.3 1 1 2 3 3 3 0 Fez1 Zn_Tnp_IS1595 PF12760.7 OAI98211.1 - 0.68 10.0 2.9 1.6 8.8 2.9 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain MMR_HSR1 PF01926.23 OAI98219.1 - 5.4e-12 45.8 0.0 2.2e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAI98219.1 - 0.00085 18.9 0.1 0.0017 17.9 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAI98219.1 - 0.0015 18.7 0.1 0.0056 16.8 0.1 2.0 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 OAI98219.1 - 0.025 14.5 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SspB PF04386.13 OAI98219.1 - 2.2 8.2 4.1 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 Stringent starvation protein B Bax1-I PF01027.20 OAI98224.1 - 4.8e-46 157.2 19.7 5.6e-46 157.0 19.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 OAI98224.1 - 0.027 14.1 16.0 0.091 12.3 16.0 1.9 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF3464 PF11947.8 OAI98224.1 - 0.88 9.3 7.2 0.12 12.1 2.3 2.0 2 1 1 3 3 3 0 Photosynthesis affected mutant 68 Pox_I5 PF04713.12 OAI98224.1 - 4.1 7.5 8.6 1 9.4 0.2 2.8 2 1 1 3 3 3 0 Poxvirus protein I5 Nop53 PF07767.11 OAI98225.1 - 2.5e-29 102.9 0.3 4.8e-29 101.9 0.3 1.5 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Phage_integrase PF00589.22 OAI98233.1 - 0.00016 21.5 0.1 0.00019 21.2 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family zf-BED PF02892.15 OAI98255.1 - 0.0048 16.9 0.3 0.013 15.5 0.3 1.8 1 0 0 1 1 1 1 BED zinc finger Phyto-Amp PF15438.6 OAI98263.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 1 0 1 1 1 0 Antigenic membrane protein of phytoplasma CLIP1_ZNF PF16641.5 OAI98268.1 - 0.02 14.8 0.6 0.041 13.8 0.6 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle Complex1_LYR PF05347.15 OAI98268.1 - 0.02 14.9 2.1 0.041 13.9 2.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Activator-TraM PF11657.8 OAI98268.1 - 0.65 9.8 6.9 1.4 8.8 6.9 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM DUF4192 PF13830.6 OAI98268.1 - 0.86 9.6 9.5 1.5 8.8 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) ThylakoidFormat PF11264.8 OAI98268.1 - 1.1 8.9 4.8 1.6 8.3 4.8 1.2 1 0 0 1 1 1 0 Thylakoid formation protein DUF4407 PF14362.6 OAI98268.1 - 1.5 8.1 8.7 2 7.7 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pinin_SDK_memA PF04696.13 OAI98268.1 - 3.3 7.8 10.6 5.3 7.1 10.6 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region SPX PF03105.19 OAI98272.1 - 1.3e-67 229.4 23.4 1e-48 167.2 11.1 2.2 1 1 1 2 2 2 2 SPX domain zf-C3HC4_3 PF13920.6 OAI98272.1 - 5.2e-07 29.4 7.0 5.2e-07 29.4 7.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAI98272.1 - 2.2e-06 27.5 7.3 3.9e-06 26.6 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAI98272.1 - 1e-05 25.6 6.7 2.1e-05 24.6 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAI98272.1 - 1.7e-05 25.1 10.3 3.7e-05 24.0 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAI98272.1 - 1.7e-05 24.5 7.6 3.2e-05 23.7 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAI98272.1 - 0.00035 20.3 8.6 0.00065 19.5 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAI98272.1 - 0.00037 20.4 6.9 0.00083 19.3 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 OAI98272.1 - 0.013 15.3 2.3 0.026 14.3 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OAI98272.1 - 0.017 15.2 8.4 0.036 14.1 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OAI98272.1 - 0.11 12.8 6.0 0.27 11.6 6.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 OAI98272.1 - 1.8 8.3 6.1 3.5 7.4 6.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger Transferase PF02458.15 OAI98278.1 - 4.2e-11 42.2 0.0 0.0018 17.0 0.0 3.1 3 0 0 3 3 3 3 Transferase family DUF4218 PF13960.6 OAI98284.1 - 0.00012 21.7 0.0 0.00029 20.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) zf_CopZ PF18423.1 OAI98285.1 - 0.061 13.3 1.4 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Zinc binding domain DUF2235 PF09994.9 OAI98290.1 - 2.1e-32 112.6 0.0 2.3e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 OAI98291.1 - 5.7e-22 78.4 0.1 8.2e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.32 OAI98299.1 - 1.9e-16 60.1 8.8 1e-05 26.1 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI98299.1 - 1.4e-14 54.2 4.8 9.7e-05 22.6 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAI98299.1 - 2.1e-05 23.7 0.4 0.00039 19.5 0.3 2.7 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAI98299.1 - 0.0023 17.8 0.4 0.073 13.0 0.4 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAI98299.1 - 0.0087 14.1 0.5 0.27 9.2 0.3 2.1 2 0 0 2 2 2 2 IKI3 family SIKE PF05769.11 OAI98309.1 - 0.00032 20.7 11.0 0.00057 19.9 4.9 2.5 2 0 0 2 2 2 1 SIKE family BSP_II PF05432.11 OAI98309.1 - 0.058 13.1 26.7 0.013 15.2 23.0 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) YabA PF06156.13 OAI98309.1 - 1.5 9.5 0.0 1.5 9.5 0.0 4.2 3 1 1 4 4 4 0 Initiation control protein YabA Presenilin PF01080.17 OAI98309.1 - 2 7.1 8.0 22 3.7 0.0 2.5 2 0 0 2 2 2 0 Presenilin VIR_N PF15912.5 OAI98309.1 - 4.4 6.8 16.9 9.1 5.8 16.9 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Nop14 PF04147.12 OAI98309.1 - 5.2 5.2 37.8 3 5.9 35.1 1.8 2 0 0 2 2 2 0 Nop14-like family RRM_1 PF00076.22 OAI98318.1 - 1.2e-08 34.6 0.0 2.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LEA_4 PF02987.16 OAI98318.1 - 0.00082 19.4 4.8 0.00082 19.4 4.8 2.8 2 1 1 3 3 3 1 Late embryogenesis abundant protein YtxH PF12732.7 OAI98318.1 - 0.0096 16.4 5.7 0.0096 16.4 5.7 3.5 3 2 1 4 4 4 1 YtxH-like protein RRM_occluded PF16842.5 OAI98318.1 - 0.01 15.7 1.7 0.016 15.0 0.0 2.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif ApoLp-III PF07464.11 OAI98318.1 - 0.48 10.5 9.7 0.16 12.1 2.1 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAI98318.1 - 0.66 10.6 9.1 0.081 13.5 2.3 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PGAP1 PF07819.13 OAI98322.1 - 0.00082 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAI98322.1 - 0.036 14.7 0.0 0.11 13.0 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3678 PF12435.8 OAI98322.1 - 0.23 10.9 3.6 0.46 9.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF1980 PF09323.10 OAI98322.1 - 8 6.3 6.2 1.9 8.3 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Phage_integrase PF00589.22 OAI98325.1 - 0.00038 20.3 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.6 OAI98325.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DDHD PF02862.17 OAI98343.1 - 0.055 13.6 0.3 0.092 12.9 0.3 1.4 1 0 0 1 1 1 0 DDHD domain DUF3245 PF11595.8 OAI98343.1 - 0.23 11.9 3.5 2.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) RVT_1 PF00078.27 OAI98349.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAI98349.1 - 0.13 11.6 0.1 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Zn_clus PF00172.18 OAI98359.1 - 3.5e-10 39.8 2.4 6.3e-10 39.0 2.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_integrase PF00589.22 OAI98367.1 - 0.00023 21.0 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family ROKNT PF08067.11 OAI98375.1 - 0.047 14.0 0.2 13 6.1 0.0 2.5 2 0 0 2 2 2 0 ROKNT (NUC014) domain DUF1542 PF07564.11 OAI98375.1 - 0.078 13.1 1.6 7.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Lactamase_B PF00753.27 OAI98379.1 - 0.022 14.7 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OAI98379.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Acyltransferase PF01553.21 OAI98380.1 - 4.4e-34 117.0 0.0 6.2e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Popeye PF04831.13 OAI98380.1 - 0.13 12.5 0.6 0.2 11.8 0.6 1.3 1 0 0 1 1 1 0 Popeye protein conserved region DUF4293 PF14126.6 OAI98381.1 - 0.15 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) ATP-grasp PF02222.22 OAI98389.1 - 4.6e-52 176.0 0.0 1.5e-29 102.7 0.0 2.2 1 1 1 2 2 2 2 ATP-grasp domain PurK_C PF17769.1 OAI98389.1 - 1.1e-17 63.5 0.0 2.3e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain AIRC PF00731.20 OAI98389.1 - 1.5e-14 53.9 0.0 4.9e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 AIR carboxylase CPSase_L_D2 PF02786.17 OAI98389.1 - 4.1e-05 23.2 0.0 0.00014 21.5 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 OAI98389.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 OAI98389.1 - 0.0024 17.4 0.0 0.011 15.2 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.18 OAI98389.1 - 0.017 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_9 PF08221.11 OAI98390.1 - 3.6e-17 62.2 0.0 1.9e-07 31.0 0.0 3.3 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain SapB_2 PF03489.17 OAI98390.1 - 0.31 11.2 0.7 0.64 10.2 0.1 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 2 RVT_1 PF00078.27 OAI98399.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAI98400.1 - 0.00046 19.8 0.5 0.002 17.7 0.4 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OAI98400.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase TraI_2_C PF07515.11 OAI98405.1 - 3.1e-49 166.0 0.0 3.6e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Putative conjugal transfer nickase/helicase TraI C-term DUF4994 PF16385.5 OAI98405.1 - 0.057 13.3 0.0 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function Pantoate_ligase PF02569.15 OAI98406.1 - 5.2e-103 343.9 0.0 6e-103 343.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase OPT PF03169.15 OAI98413.1 - 3.3e-90 303.5 40.1 3.8e-90 303.3 40.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3306 PF11748.8 OAI98413.1 - 1.3 9.9 3.3 2.4 9.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Methyltransf_2 PF00891.18 OAI98416.1 - 1.4e-21 76.8 0.0 2.6e-21 75.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 OAI98416.1 - 0.00015 22.4 0.0 0.00034 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAI98416.1 - 0.0021 18.7 0.0 0.0051 17.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAI98416.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF3678 PF12435.8 OAI98416.1 - 0.045 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Pkinase PF00069.25 OAI98420.1 - 1.9e-43 148.7 0.0 9.3e-41 139.9 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAI98420.1 - 6.7e-23 81.3 0.0 2e-22 79.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAI98420.1 - 0.00077 18.9 0.2 0.0012 18.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAI98420.1 - 0.073 12.4 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like RNA_pol_3_Rpc31 PF11705.8 OAI98439.1 - 2.3e-26 93.5 4.1 3.8e-26 92.8 4.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Vps16_N PF04841.13 OAI98440.1 - 1.5e-12 47.0 0.0 3.4e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 OAI98440.1 - 0.2 12.0 0.0 0.43 10.9 0.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 OAI98445.1 - 1.5e-40 139.4 0.0 1.6e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 rve PF00665.26 OAI98453.1 - 7.3e-05 22.9 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAI98453.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain STE2 PF02116.15 OAI98460.1 - 9.2e-05 21.9 1.3 0.00019 20.8 1.3 1.5 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PGG PF13962.6 OAI98460.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function Phage_integrase PF00589.22 OAI98465.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family RVT_1 PF00078.27 OAI98466.1 - 0.0034 16.9 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAI98466.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Sec1 PF00995.23 OAI98474.1 - 0.062 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Sigma70_ner PF04546.13 OAI98483.1 - 0.011 15.6 0.7 0.011 15.6 0.7 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region 4HB_MCP_1 PF12729.7 OAI98483.1 - 0.34 10.4 1.8 0.51 9.9 0.1 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FAM104 PF15434.6 OAI98483.1 - 0.91 10.1 12.9 6.4 7.4 12.9 2.5 1 0 0 1 1 1 0 Family 104 MFMR_assoc PF16596.5 OAI98483.1 - 0.91 10.0 16.6 3.2 8.2 16.0 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR Plasmodium_Vir PF05795.11 OAI98483.1 - 3.4 7.0 5.8 7.9 5.8 5.8 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SR-25 PF10500.9 OAI98489.1 - 0.062 12.9 6.8 0.092 12.3 6.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OAI98489.1 - 0.15 12.7 3.7 0.28 11.9 3.7 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein GTP_EFTU PF00009.27 OAI98496.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF4407 PF14362.6 OAI98502.1 - 0.0066 15.8 5.2 0.0079 15.6 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0492 PF15744.5 OAI98502.1 - 0.26 10.5 4.2 0.28 10.4 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Ribosomal_60s PF00428.19 OAI98503.1 - 2e-24 86.0 9.9 2e-24 86.0 9.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 OAI98503.1 - 7.1e-23 80.6 0.1 1.8e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OAI98503.1 - 4.3e-21 74.7 0.1 8.5e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P MULE PF10551.9 OAI98509.1 - 5.5e-20 71.6 0.2 1.2e-19 70.5 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAI98509.1 - 0.00042 21.0 2.4 0.0009 19.9 2.4 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.18 OAI98509.1 - 0.00074 18.5 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.6 OAI98509.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 DDE domain AFT PF08731.11 OAI98509.1 - 0.14 12.6 1.9 0.21 12.0 0.7 1.9 2 1 0 2 2 2 0 Transcription factor AFT DUF1722 PF08349.11 OAI98509.1 - 0.15 12.3 0.4 0.29 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) gp12-short_mid PF09089.10 OAI98509.1 - 0.21 11.8 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain AIP3 PF03915.13 OAI98522.1 - 0.32 10.0 3.6 2.2 7.3 3.8 1.9 1 1 0 1 1 1 0 Actin interacting protein 3 DUF3106 PF11304.8 OAI98522.1 - 1.1 9.7 5.8 0.71 10.4 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Sec1 PF00995.23 OAI98540.1 - 7.9e-07 28.7 0.1 9.8e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Myb_DNA-bind_3 PF12776.7 OAI98544.1 - 1.1e-15 58.4 0.7 2.2e-15 57.4 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAI98544.1 - 4.9e-06 26.8 1.6 2.8e-05 24.4 1.6 2.1 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MFS_1 PF07690.16 OAI98553.1 - 9.7e-10 37.9 23.3 9.7e-10 37.9 23.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily NifW PF03206.14 OAI98560.1 - 0.15 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Pardaxin PF07425.11 OAI98560.1 - 0.79 9.4 4.3 0.95 9.1 1.6 2.2 2 0 0 2 2 2 0 Pardaxin TFIIA PF03153.13 OAI98564.1 - 5 7.0 28.3 6.3 6.7 28.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRK PF00485.18 OAI98565.1 - 3.9e-07 30.0 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OAI98565.1 - 3.5e-05 24.4 0.0 0.00023 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 OAI98565.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OAI98565.1 - 0.054 13.6 0.2 0.15 12.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAI98565.1 - 0.16 12.4 0.8 0.59 10.5 0.4 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF572 PF04502.13 OAI98579.1 - 0.00092 18.9 1.7 0.0012 18.6 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Lipase_chap PF03280.14 OAI98579.1 - 0.025 14.6 3.2 0.039 13.9 3.2 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein RT_RNaseH_2 PF17919.1 OAI98586.1 - 7.2e-22 77.3 0.0 1.4e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI98586.1 - 1.9e-19 70.1 0.0 3.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAI98586.1 - 8.6e-15 54.9 0.0 2.2e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI98586.1 - 3.8e-12 46.1 0.0 6.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI98586.1 - 2.1e-10 40.8 0.0 4.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAI98586.1 - 0.039 14.2 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger FAS_meander PF17951.1 OAI98591.1 - 4.2e-41 140.2 0.0 6.8e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 OAI98591.1 - 8e-08 32.5 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Acyl_transf_1 PF00698.21 OAI98592.1 - 7.6e-56 189.9 0.0 1.1e-49 169.7 0.1 2.2 1 1 1 2 2 2 2 Acyl transferase domain MaoC_dehydratas PF01575.19 OAI98592.1 - 6.1e-25 87.2 0.0 2.7e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain GSH_synth_ATP PF03917.17 OAI98592.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain NifU_N PF01592.16 OAI98596.1 - 1e-54 184.1 0.1 2.1e-54 183.1 0.1 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain NMO PF03060.15 OAI98597.1 - 6.1e-45 154.0 0.9 8e-44 150.4 0.9 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAI98597.1 - 5.3e-09 35.5 0.5 0.0016 17.5 0.3 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAI98597.1 - 0.00024 20.2 0.2 0.00038 19.6 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAI98597.1 - 0.047 12.8 1.2 0.17 11.0 1.2 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 OAI98597.1 - 0.047 13.1 0.1 0.099 12.1 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Abhydrolase_5 PF12695.7 OAI98604.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 OAI98604.1 - 0.11 13.1 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nfu_N PF08712.11 OAI98620.1 - 5.1e-33 113.0 0.0 2.8e-32 110.6 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAI98620.1 - 1.2e-24 86.2 0.0 1.9e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 OAI98620.1 - 0.082 13.0 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Spt20 PF12090.8 OAI98620.1 - 6 6.4 11.1 1.1e+02 2.2 0.0 2.1 2 0 0 2 2 2 0 Spt20 family Pyr_redox_2 PF07992.14 OAI98621.1 - 2e-51 175.0 0.3 2.3e-51 174.8 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAI98621.1 - 1.6e-18 67.0 0.1 1.3e-15 57.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAI98621.1 - 7.6e-18 64.8 0.4 3.6e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAI98621.1 - 4.3e-06 26.3 0.1 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAI98621.1 - 7.2e-06 25.4 0.0 0.00015 21.1 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAI98621.1 - 2.7e-05 23.5 2.0 0.0064 15.6 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAI98621.1 - 2.9e-05 23.5 0.2 0.024 13.9 0.0 3.0 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OAI98621.1 - 0.00011 22.3 0.4 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OAI98621.1 - 0.0003 21.2 0.1 0.021 15.3 0.0 2.8 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAI98621.1 - 0.0019 17.4 3.8 0.0061 15.7 0.5 2.5 2 1 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 OAI98621.1 - 0.0045 15.9 0.1 0.064 12.1 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OAI98621.1 - 0.005 15.6 0.1 0.033 12.9 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 OAI98621.1 - 0.009 16.1 0.0 7.4 6.6 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAI98621.1 - 0.011 14.9 0.1 0.56 9.3 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAI98621.1 - 0.016 14.8 4.6 0.12 11.9 0.3 3.1 1 1 1 3 3 3 0 FAD dependent oxidoreductase Homeodomain PF00046.29 OAI98633.1 - 1.5e-22 79.2 1.5 6.6e-14 51.5 0.1 2.6 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 OAI98633.1 - 6.1e-07 29.2 1.2 0.00041 20.2 0.1 2.6 2 0 0 2 2 2 2 Homeobox KN domain HTH_28 PF13518.6 OAI98633.1 - 0.012 15.8 0.2 6.4 7.0 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 OAI98633.1 - 0.022 14.7 0.1 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain 2Fe-2S_thioredx PF01257.19 OAI98633.1 - 0.047 13.5 0.0 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin Sigma70_ner PF04546.13 OAI98633.1 - 6.2 6.6 9.9 12 5.7 4.6 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-CCHC PF00098.23 OAI98639.1 - 2.4e-06 27.4 1.9 2.4e-06 27.4 1.9 1.8 2 0 0 2 2 2 1 Zinc knuckle DUF5562 PF17717.1 OAI98639.1 - 0.065 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5562) zf-CCHC_2 PF13696.6 OAI98639.1 - 0.066 13.0 0.4 0.066 13.0 0.4 1.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAI98639.1 - 0.2 11.4 0.5 0.3 10.8 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 OAI98639.1 - 0.28 10.7 2.6 0.6 9.6 2.6 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain DUF1329 PF07044.11 OAI98646.1 - 1.6e-73 248.1 0.0 1.8e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 OAI98646.1 - 1.5e-17 63.9 0.1 1.9e-09 37.5 0.1 2.2 2 0 0 2 2 2 2 Outer membrane lipoprotein-sorting protein MCPsignal PF00015.21 OAI98647.1 - 1.1e-42 145.8 25.8 3e-42 144.4 17.1 2.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 OAI98647.1 - 9.3e-13 48.3 0.0 2.7e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OAI98647.1 - 1.8e-11 44.2 0.0 7.1e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAI98647.1 - 1.6e-10 41.0 0.0 1.9e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAI98647.1 - 1.3e-07 31.8 0.2 1.2e-06 28.7 0.0 2.7 2 1 1 3 3 3 1 PAS fold PAS_8 PF13188.7 OAI98647.1 - 0.0022 17.9 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain FeoC PF09012.10 OAI98647.1 - 0.48 10.5 3.3 19 5.4 0.0 3.0 3 0 0 3 3 3 0 FeoC like transcriptional regulator Noelin-1 PF12308.8 OAI98647.1 - 0.68 9.9 5.1 3.9 7.5 0.2 3.0 3 0 0 3 3 3 0 Neurogenesis glycoprotein Seryl_tRNA_N PF02403.22 OAI98647.1 - 0.84 9.9 4.4 3.3 8.0 0.1 3.2 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 OAI98647.1 - 1.3 9.1 14.7 0.29 11.1 3.1 3.2 2 1 1 3 3 3 0 Laminin Domain II DUF948 PF06103.11 OAI98647.1 - 1.4 9.2 11.5 17 5.8 0.2 4.2 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) 5-FTHF_cyc-lig PF01812.20 OAI98656.1 - 1e-28 100.5 0.7 1.1e-26 93.8 0.0 2.5 2 1 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family CBFD_NFYB_HMF PF00808.23 OAI98658.1 - 2.4e-14 53.4 0.0 2.6e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAI98658.1 - 0.00031 21.1 0.0 0.00032 21.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 OAI98658.1 - 0.027 14.6 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TRAM PF01938.20 OAI98658.1 - 0.054 13.5 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 TRAM domain CK_II_beta PF01214.18 OAI98662.1 - 6e-75 251.1 0.1 1.5e-74 249.8 0.0 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit BSP_II PF05432.11 OAI98662.1 - 0.097 12.4 23.6 0.19 11.4 23.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIA PF03153.13 OAI98662.1 - 0.66 9.9 29.4 0.048 13.6 23.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.6 OAI98662.1 - 0.95 9.3 12.6 0.28 11.0 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 51 PPP4R2 PF09184.11 OAI98662.1 - 8.2 5.9 19.1 13 5.3 19.1 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4400 PF14348.6 OAI98692.1 - 6.4e-63 212.0 6.4 7.1e-63 211.8 6.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) CDP-OH_P_transf PF01066.21 OAI98692.1 - 0.14 12.9 0.7 0.43 11.4 0.7 1.8 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase GATA PF00320.27 OAI98699.1 - 4.9e-05 22.9 4.8 0.00013 21.5 3.8 2.2 1 1 1 2 2 2 1 GATA zinc finger ADK_lid PF05191.14 OAI98699.1 - 0.23 11.4 1.9 0.49 10.4 1.9 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid Glyco_hydro_92N PF17678.1 OAI98705.1 - 1.7e-17 64.1 2.5 2.3e-17 63.7 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Pkr1 PF08636.10 OAI98714.1 - 6.1e-25 87.1 1.1 7.5e-25 86.9 1.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MMR_HSR1_Xtn PF16897.5 OAI98715.1 - 3.6e-41 139.5 0.2 7.3e-41 138.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAI98715.1 - 1.9e-20 72.7 0.1 3.5e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAI98715.1 - 3.9e-20 72.0 0.0 8.6e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAI98715.1 - 6.7e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAI98715.1 - 0.0016 18.5 0.2 0.065 13.3 0.0 2.4 1 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 OAI98715.1 - 0.0035 17.7 0.6 0.17 12.3 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 OAI98715.1 - 0.029 13.4 0.0 0.067 12.3 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain DUF1002 PF06207.11 OAI98715.1 - 0.073 12.6 0.5 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) MSA-2c PF12238.8 OAI98726.1 - 4.8 7.1 7.2 7 6.6 7.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RVT_1 PF00078.27 OAI98727.1 - 4.8e-18 65.5 0.0 6.9e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pho88 PF10032.9 OAI98757.1 - 1e-63 213.9 0.0 1.1e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CTK3 PF12243.8 OAI98758.1 - 1.1e-23 83.6 0.0 1.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAI98758.1 - 1.3e-17 63.7 0.4 6.8e-11 42.2 0.1 2.5 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 C-terminus RT_RNaseH_2 PF17919.1 OAI98777.1 - 9.9e-21 73.7 0.0 1.2e-12 47.7 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI98777.1 - 7.2e-17 61.6 0.0 4.2e-11 43.1 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI98777.1 - 1.4e-15 57.1 0.0 3.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAI98777.1 - 2.9e-14 53.1 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAI98777.1 - 6.2e-12 45.8 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Methyltransf_23 PF13489.6 OAI98792.1 - 8.6e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAI98792.1 - 5.8e-09 36.6 0.0 9.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAI98792.1 - 1.7e-08 35.0 0.0 3.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAI98792.1 - 7e-05 23.5 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAI98792.1 - 0.0002 21.2 0.0 0.0008 19.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAI98792.1 - 0.00029 19.9 0.0 0.0004 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 OAI98792.1 - 0.0033 17.2 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 OAI98792.1 - 0.079 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Cmc1 PF08583.10 OAI98807.1 - 8.1e-11 41.8 1.6 1.2e-10 41.2 1.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SH3_1 PF00018.28 OAI98814.1 - 7.5e-11 41.5 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAI98814.1 - 2.5e-08 33.6 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAI98814.1 - 2.1e-07 30.5 0.0 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Polysacc_deac_1 PF01522.21 OAI98824.1 - 1.2e-22 80.1 0.0 2.7e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Gly_kinase PF02595.15 OAI98825.1 - 0.047 12.7 0.4 0.068 12.2 0.4 1.1 1 0 0 1 1 1 0 Glycerate kinase family DUF1768 PF08719.11 OAI98835.1 - 2.3e-10 40.9 0.0 4.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NAD_binding_8 PF13450.6 OAI98844.1 - 2.8e-14 53.1 0.0 8.2e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAI98844.1 - 0.0005 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAI98844.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAI98844.1 - 0.063 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAI98844.1 - 0.064 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAI98844.1 - 0.073 12.4 0.0 1.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Ras PF00071.22 OAI98851.1 - 4.2e-54 182.5 0.0 4.8e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAI98851.1 - 2.2e-21 76.3 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAI98851.1 - 2.3e-07 30.4 0.0 4.1e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 OAI98851.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OAI98851.1 - 0.094 12.5 0.0 3.3 7.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OAI98851.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.24 OAI98858.1 - 0.0033 16.3 5.1 0.0042 16.0 5.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter zf-CCHC PF00098.23 OAI98868.1 - 0.001 19.0 0.2 0.0015 18.5 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.14 OAI98869.1 - 3.3e-29 102.2 0.0 5.7e-28 98.2 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAI98869.1 - 3.3e-19 69.2 0.0 6e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAI98869.1 - 2.2e-06 27.4 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAI98869.1 - 0.0038 17.0 0.0 0.0097 15.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CRAL_TRIO PF00650.20 OAI98876.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain Defensin_big PF14862.6 OAI98876.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Big defensin TPK_catalytic PF04263.16 OAI98877.1 - 3.2e-26 91.7 0.0 4.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAI98877.1 - 1.5e-10 40.6 0.0 2.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Med3 PF11593.8 OAI98886.1 - 0.37 9.9 11.2 0.44 9.7 11.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3275 PF11679.8 OAI98886.1 - 1.7 8.6 3.1 2.9 7.8 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RT_RNaseH PF17917.1 OAI98887.1 - 3.8e-11 43.2 0.0 8.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAI98887.1 - 1.4e-05 25.6 0.0 3.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 OAI98887.1 - 2.7e-05 24.1 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAI98887.1 - 0.001 19.6 0.0 0.0023 18.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI98887.1 - 0.087 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-C3HC4_3 PF13920.6 OAI98898.1 - 0.27 11.1 3.5 0.51 10.2 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tubulin PF00091.25 OAI98928.1 - 5.5e-63 212.7 0.0 8.6e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAI98928.1 - 2.1e-36 124.9 0.0 3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAI98928.1 - 0.00032 21.0 0.0 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAI98928.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAI98928.1 - 0.0037 16.5 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin like ART PF01129.18 OAI98928.1 - 0.076 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase CPSase_L_D2 PF02786.17 OAI98936.1 - 2.9e-93 311.2 0.0 2.3e-82 275.6 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAI98936.1 - 1.4e-40 138.5 0.2 5e-40 136.7 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OAI98936.1 - 1.5e-09 37.6 0.0 3.4e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAI98936.1 - 2.9e-09 36.8 0.0 1.5e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 OAI98936.1 - 9.2e-06 25.3 0.1 0.012 15.1 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAI98936.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OAI98936.1 - 0.0002 21.4 0.0 0.00061 19.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Peptidase_M17_N PF02789.17 OAI98936.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Aldo_ket_red PF00248.21 OAI98946.1 - 8.4e-44 149.9 0.0 1.4e-28 99.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family 6PGD PF00393.19 OAI98947.1 - 6.3e-123 409.8 0.0 7.6e-123 409.5 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain TPR_10 PF13374.6 OAI98962.1 - 5.9e-13 48.2 19.0 0.0013 18.5 0.7 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAI98962.1 - 1.4e-07 31.6 24.9 0.0067 16.7 0.7 5.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAI98962.1 - 8e-05 22.5 15.5 0.025 14.7 0.4 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAI98962.1 - 0.00072 20.2 14.9 0.024 15.4 0.4 5.6 3 2 2 5 5 5 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OAI98962.1 - 0.0019 18.3 9.6 0.53 10.4 1.4 4.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_1 PF00515.28 OAI98962.1 - 0.002 17.9 5.8 0.18 11.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OAI98962.1 - 0.0097 14.7 1.5 1.3 7.7 0.3 2.5 2 1 0 2 2 2 2 Fungal protein kinase TPR_7 PF13176.6 OAI98962.1 - 0.06 13.4 2.1 5.8 7.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAI98962.1 - 0.17 12.2 9.0 6.1 7.3 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 OAI98962.1 - 0.46 10.6 6.6 3.9 7.6 1.8 3.3 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain RyR PF02026.16 OAI98962.1 - 0.5 10.6 3.4 1.3 9.2 0.2 2.8 2 1 1 3 3 3 0 RyR domain TPR_6 PF13174.6 OAI98962.1 - 4.7 8.1 8.7 21 6.0 0.4 5.3 5 2 0 5 5 5 0 Tetratricopeptide repeat Varsurf_PPLC PF03490.13 OAI98971.1 - 6.1e-05 22.9 0.1 0.00015 21.7 0.1 1.7 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C DUF3662 PF12401.8 OAI98971.1 - 0.16 12.3 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Phage_AlpA PF05930.12 OAI98979.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) DUF2347 PF09804.9 OAI98989.1 - 6.4e-29 101.4 0.0 3.4e-28 99.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 OAI98989.1 - 0.0019 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.12 OAI98989.1 - 0.03 14.8 3.3 0.3 11.6 0.0 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nuc_recep-AF1 PF11825.8 OAI98989.1 - 0.29 11.2 5.6 0.76 9.8 4.5 2.3 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 PPP4R2 PF09184.11 OAI98989.1 - 10 5.6 6.3 6.6 6.2 0.6 2.3 2 0 0 2 2 2 0 PPP4R2 FHA PF00498.26 OAI99011.1 - 0.081 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 FHA domain DNA_pol_viral_C PF00336.18 OAI99024.1 - 0.15 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain TFIIA PF03153.13 OAI99024.1 - 8 6.3 16.0 11 5.9 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S8 PF00082.22 OAI99034.1 - 9.8e-41 139.9 0.0 2.5e-40 138.6 0.0 1.6 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAI99034.1 - 3e-15 56.9 0.5 8.4e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Fn3-like domain IDO PF01231.18 OAI99041.1 - 1.9e-124 415.8 0.0 4.6e-124 414.5 0.0 1.6 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase TFIIA PF03153.13 OAI99041.1 - 7.4 6.5 11.3 2.5 8.0 1.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HTH_Tnp_Tc5 PF03221.16 OAI99052.1 - 1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.6 OAI99052.1 - 0.00032 20.4 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.6 OAI99052.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 OAI99052.1 - 0.0075 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 OAI99052.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 OAI99052.1 - 0.0093 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 OAI99052.1 - 0.011 15.7 0.5 0.025 14.5 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 OAI99052.1 - 0.02 14.6 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 OAI99052.1 - 0.047 13.8 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 OAI99052.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 OAI99052.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain eIF-3_zeta PF05091.12 OAI99052.1 - 1.2 8.1 5.5 1.7 7.5 5.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 OAI99052.1 - 2.8 7.2 5.3 5.7 6.2 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-BED PF02892.15 OAI99064.1 - 5.4e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 BED zinc finger DUF1566 PF07603.11 OAI99064.1 - 0.045 14.1 0.1 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1566) DUF4379 PF14311.6 OAI99064.1 - 0.15 12.4 1.6 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Probable Zinc-ribbon domain NAD_binding_10 PF13460.6 OAI99080.1 - 0.01 15.7 0.1 0.062 13.2 0.1 2.1 1 1 0 1 1 1 0 NAD(P)H-binding DUF4702 PF15774.5 OAI99080.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) RVT_3 PF13456.6 OAI99103.1 - 0.0023 17.7 0.2 0.0047 16.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAI99103.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.5 1 1 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.22 OAI99104.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family LIP PF03583.14 OAI99115.1 - 6.4e-34 117.6 0.3 8e-34 117.3 0.3 1.1 1 0 0 1 1 1 1 Secretory lipase UPF0029 PF01205.19 OAI99133.1 - 1.7e-28 99.0 0.0 4.4e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OAI99133.1 - 0.0014 18.9 1.4 0.026 14.8 1.3 2.3 1 1 0 1 1 1 1 RWD domain E1-E2_ATPase PF00122.20 OAI99155.1 - 2.2e-38 131.6 3.1 2.2e-38 131.6 3.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OAI99155.1 - 4e-15 55.2 0.0 7.6e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAI99155.1 - 9e-14 51.3 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAI99155.1 - 2.7e-10 40.9 0.2 5.5e-09 36.6 0.3 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 OAI99155.1 - 0.017 14.9 2.4 0.66 9.8 0.4 3.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Frag1 PF10277.9 OAI99155.1 - 0.8 9.2 6.3 0.71 9.4 3.0 2.2 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family Membrane_bind PF14564.6 OAI99162.1 - 0.094 13.2 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Membrane binding ArgoL2 PF16488.5 OAI99166.1 - 5e-09 36.4 0.2 7.7e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 OAI99166.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.3 1 1 0 1 1 1 1 PAZ domain Aconitase_B_N PF11791.8 OAI99166.1 - 0.037 14.1 0.1 0.052 13.6 0.1 1.2 1 0 0 1 1 1 0 Aconitate B N-terminal domain DUF2106 PF09879.9 OAI99211.1 - 0.019 14.5 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) WD40 PF00400.32 OAI99225.1 - 4.1e-14 52.8 3.8 8e-07 29.7 0.1 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI99225.1 - 0.0069 16.7 0.0 0.2 12.0 0.0 2.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 OAI99225.1 - 0.02 14.3 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Nup160 PF11715.8 OAI99225.1 - 0.031 12.9 0.0 2.2 6.8 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 MCM_bind PF09739.9 OAI99226.1 - 1.7e-60 205.1 0.0 3.3e-48 164.5 0.0 4.5 3 1 0 3 3 3 3 Mini-chromosome maintenance replisome factor LCCL PF03815.19 OAI99260.1 - 1.1e-16 60.7 0.0 2.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF4637 PF15470.6 OAI99270.1 - 0.15 11.7 4.3 0.1 12.3 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) RVT_2 PF07727.14 OAI99271.1 - 1.2e-38 133.2 0.0 1.6e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3835 PF12927.7 OAI99283.1 - 0.1 13.5 0.1 0.15 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) DUF885 PF05960.11 OAI99284.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Retrotran_gag_2 PF14223.6 OAI99285.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAI99285.1 - 0.14 12.3 10.6 0.054 13.6 7.4 2.0 2 0 0 2 2 2 0 Zinc knuckle DNA_pol_phi PF04931.13 OAI99293.1 - 1.3 7.1 6.0 1.6 6.8 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CAP PF00188.26 OAI99309.1 - 6e-06 27.1 0.1 6.9e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RIO1 PF01163.22 OAI99310.1 - 6.4e-64 215.0 0.7 6.4e-64 215.0 0.7 2.5 2 1 0 2 2 2 1 RIO1 family SDA1 PF05285.12 OAI99310.1 - 2.3 7.6 32.2 0.88 8.9 18.9 2.4 2 0 0 2 2 2 0 SDA1 DDE_Tnp_4 PF13359.6 OAI99323.1 - 2.9e-16 59.6 0.0 4.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4611 PF15387.6 OAI99333.1 - 0.03 14.5 2.9 0.056 13.7 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Hydrolase_6 PF13344.6 OAI99334.1 - 1.2e-17 63.9 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Dimer_Tnp_hAT PF05699.14 OAI99346.1 - 5.2e-16 58.2 0.0 9.5e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-FokI_C PF09254.11 OAI99346.1 - 0.041 13.2 0.9 0.083 12.2 0.9 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal DUF4413 PF14372.6 OAI99346.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.25 OAI99347.1 - 1.8e-33 116.0 0.0 2.3e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI99347.1 - 1.2e-17 64.1 0.0 1.4e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAI99347.1 - 7.8e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAI99347.1 - 0.00017 21.0 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAI99347.1 - 0.01 14.9 0.3 0.014 14.4 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NIF PF03031.18 OAI99347.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase RIO1 PF01163.22 OAI99347.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 OAI99368.1 - 5.1e-24 84.8 0.0 8.4e-22 77.6 0.0 2.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAI99368.1 - 2.9e-16 59.7 0.0 3.6e-14 52.9 0.0 2.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAI99368.1 - 0.0037 16.8 0.0 0.005 16.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAI99368.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAI99369.1 - 3e-23 82.3 0.0 5.4e-15 55.4 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAI99369.1 - 1.8e-16 60.5 0.0 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAI99369.1 - 3.5e-06 26.7 0.0 7.1e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAI99369.1 - 0.00034 20.5 0.0 0.00061 19.7 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAI99369.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Trns_repr_metal PF02583.17 OAI99383.1 - 0.058 13.8 0.8 0.086 13.2 0.2 1.6 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor Phage_int_SAM_1 PF02899.17 OAI99384.1 - 0.029 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PikAIV_N PF18605.1 OAI99384.1 - 0.05 13.2 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CTP_transf_like PF01467.26 OAI99391.1 - 1.4e-07 31.8 0.0 3.7e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 OAI99391.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Mito_carr PF00153.27 OAI99392.1 - 5.8e-56 186.4 7.4 2.3e-22 78.7 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein TMEM126 PF07114.11 OAI99392.1 - 0.0024 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 126 G_path_suppress PF15991.5 OAI99392.1 - 0.2 11.8 0.6 0.29 11.2 0.6 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Methyltransf_10 PF05971.12 OAI99400.1 - 1.1e-51 176.0 0.0 5.3e-31 108.1 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase Methyltransf_31 PF13847.6 OAI99400.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mod_r PF07200.13 OAI99401.1 - 1.3e-19 70.7 5.7 4.1e-19 69.1 5.7 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Herpes_UL14 PF03580.14 OAI99401.1 - 0.0036 17.6 1.6 0.0053 17.0 0.6 1.8 2 0 0 2 2 2 1 Herpesvirus UL14-like protein Glyco_H_20C_C PF18088.1 OAI99401.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain JIP_LZII PF16471.5 OAI99401.1 - 0.039 14.1 0.7 0.09 13.0 0.7 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 OAI99401.1 - 0.063 13.5 8.7 0.1 12.8 8.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4735 PF15882.5 OAI99401.1 - 0.18 11.3 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) PRP3 PF08572.10 OAI99420.1 - 5.8e-67 225.7 6.3 5.8e-67 225.7 6.3 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAI99420.1 - 3.2e-35 121.4 1.0 5.2e-35 120.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DinB_2 PF12867.7 OAI99420.1 - 0.43 11.1 2.0 0.94 10.0 0.7 2.4 2 0 0 2 2 2 0 DinB superfamily Pannexin_like PF12534.8 OAI99420.1 - 0.78 8.8 3.6 1.3 8.1 3.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 LSM PF01423.22 OAI99421.1 - 3.6e-14 52.2 0.0 4.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAI99421.1 - 0.0069 16.0 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Hfq protein RT_RNaseH PF17917.1 OAI99448.1 - 1e-16 61.1 0.0 7.9e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI99448.1 - 7.1e-16 58.1 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI99448.1 - 2.6e-08 33.7 0.0 4.9e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YjbT PF17089.5 OAI99448.1 - 0.019 14.9 0.0 0.081 12.9 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein family DUF1707 PF08044.11 OAI99448.1 - 1.3 9.2 3.0 0.83 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Sel1 PF08238.12 OAI99459.1 - 2.6e-37 126.4 29.6 5.6e-06 26.9 0.8 8.5 8 0 0 8 8 8 7 Sel1 repeat TPR_19 PF14559.6 OAI99459.1 - 0.044 14.3 4.8 1.2 9.7 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAI99459.1 - 0.16 12.7 2.7 2.8 8.8 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 OAI99470.1 - 2e-13 50.4 2.0 4.2e-13 49.4 0.7 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAI99470.1 - 0.00016 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) RVP_2 PF08284.11 OAI99471.1 - 2.3e-09 37.2 0.0 3.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OAI99471.1 - 0.055 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 OAI99471.1 - 0.079 13.5 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1455 PF07306.11 OAI99471.1 - 0.3 11.1 1.8 9.3 6.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) RVT_1 PF00078.27 OAI99505.1 - 7.3e-16 58.3 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAI99505.1 - 8.3e-06 25.6 0.7 1.7e-05 24.6 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAI99505.1 - 5.2e-05 23.5 1.4 0.00035 20.8 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 OAI99505.1 - 0.17 11.8 0.4 0.27 11.1 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Uricase PF01014.18 OAI99511.1 - 3.7e-59 198.7 0.0 1.2e-32 112.9 0.0 2.3 2 1 0 2 2 2 2 Uricase RAG1 PF12940.7 OAI99512.1 - 0.3 9.1 5.4 0.41 8.7 5.4 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase LMBR1 PF04791.16 OAI99512.1 - 0.72 8.7 2.4 0.75 8.6 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SOG2 PF10428.9 OAI99512.1 - 3.2 6.9 19.5 4 6.5 19.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TMCO5 PF14992.6 OAI99512.1 - 3.2 7.2 20.0 4.5 6.8 20.0 1.1 1 0 0 1 1 1 0 TMCO5 family DUF334 PF03904.13 OAI99512.1 - 5.2 6.5 10.5 7.9 6.0 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Thi4 PF01946.17 OAI99535.1 - 2.4e-14 53.2 0.3 2.1e-07 30.5 0.1 2.3 1 1 1 2 2 2 2 Thi4 family Malate_synthase PF01274.22 OAI99563.1 - 0.0048 15.2 0.0 0.0053 15.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Serglycin PF04360.12 OAI99578.1 - 9.9 6.1 16.4 13 5.8 8.0 2.3 2 0 0 2 2 2 0 Serglycin DUF1542 PF07564.11 OAI99579.1 - 0.075 13.2 2.4 0.11 12.6 2.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) MFS_1 PF07690.16 OAI99608.1 - 3.1e-33 115.2 12.1 3.1e-33 115.2 12.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAI99608.1 - 1.1e-09 37.7 0.2 1.1e-09 37.7 0.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAI99608.1 - 0.051 11.9 8.7 1.6 6.9 1.5 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 OAI99609.1 - 4e-13 49.6 6.1 0.039 14.8 0.0 7.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI99609.1 - 1.6e-07 31.5 0.0 0.088 13.1 0.0 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RVT_2 PF07727.14 OAI99625.1 - 5.1e-49 167.1 0.0 7.9e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAI99625.1 - 1.5e-20 73.3 0.0 2.3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAI99625.1 - 6.9e-16 58.5 0.0 1.7e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAI99625.1 - 2.1e-06 27.5 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAI99625.1 - 0.098 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.20 OAI99625.1 - 0.11 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 OAI99625.1 - 1.2 9.0 3.8 2.7 7.9 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 OAI99625.1 - 6.9 6.9 8.5 0.22 11.7 2.1 2.0 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 OAI99636.1 - 3.3e-24 85.6 0.0 5.1e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI99636.1 - 4.8e-13 49.0 0.0 9.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAI99636.1 - 0.0011 19.6 0.1 0.0023 18.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI99636.1 - 0.012 16.1 0.1 0.038 14.6 0.1 1.9 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease dUTPase PF00692.19 OAI99636.1 - 0.013 15.1 0.0 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 dUTPase RT_RNaseH PF17917.1 OAI99636.1 - 0.2 11.9 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pyr_redox_2 PF07992.14 OAI99668.1 - 8.1e-49 166.4 0.1 1e-48 166.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAI99668.1 - 1.9e-10 41.1 0.0 1.8e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAI99668.1 - 0.022 14.3 2.6 20 4.6 0.0 3.7 4 1 1 5 5 5 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAI99668.1 - 0.08 12.2 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF5521 PF17659.1 OAI99678.1 - 0.43 8.4 3.8 0.59 7.9 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) CCDC24 PF15669.5 OAI99678.1 - 1.7 8.5 0.0 1.7 8.5 0.0 3.3 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 24 family DDE_3 PF13358.6 OAI99693.1 - 4.6e-25 88.1 0.0 6.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 OAI99693.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Pyridoxal_deC PF00282.19 OAI99704.1 - 1.1e-70 238.2 0.0 5.1e-41 140.6 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAI99704.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V CorA PF01544.18 OAI99751.1 - 1e-08 34.8 4.8 2.4e-08 33.6 4.8 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PhetRS_B1 PF18262.1 OAI99751.1 - 0.4 10.9 1.3 0.98 9.7 0.2 2.1 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain DUF4603 PF15376.6 OAI99751.1 - 4.5 4.5 10.3 6.7 4.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Sporozoite_P67 PF05642.11 OAI99751.1 - 5.7 4.9 7.9 8.6 4.3 7.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen dCache_1 PF02743.18 OAI99751.1 - 6.3 6.5 7.3 80 2.9 7.3 2.2 1 1 0 1 1 1 0 Cache domain GDP_Man_Dehyd PF16363.5 OAI99752.1 - 1.8e-42 145.9 0.0 2.3e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAI99752.1 - 1.8e-41 142.2 0.0 2.1e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAI99752.1 - 2.2e-12 46.6 0.0 8.3e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAI99752.1 - 3.4e-07 29.7 0.0 5.1e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAI99752.1 - 1.2e-06 27.9 0.0 2.8e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAI99752.1 - 1.2e-05 24.6 0.0 2.6e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OAI99752.1 - 7.7e-05 22.7 0.0 0.00024 21.1 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OAI99752.1 - 0.00074 19.0 0.0 0.0017 17.8 0.0 1.7 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OAI99752.1 - 0.0013 18.6 0.0 0.0077 16.1 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Ribonuc_L-PSP PF01042.21 OAI99752.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP Lyase_aromatic PF00221.19 OAI99767.1 - 0.015 13.9 0.2 1.8 7.2 0.0 2.0 1 1 1 2 2 2 0 Aromatic amino acid lyase Spc7 PF08317.11 OAI99768.1 - 0.00065 18.7 0.4 0.00078 18.4 0.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DHR10 PF18595.1 OAI99768.1 - 0.0035 17.4 2.1 0.005 16.9 2.1 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain HrpB7 PF09486.10 OAI99768.1 - 0.0049 17.3 0.6 0.0067 16.8 0.6 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Methyltransf_2 PF00891.18 OAI99783.1 - 3.8e-07 29.6 0.0 6.9e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain DUF3678 PF12435.8 OAI99783.1 - 0.0024 17.2 1.0 0.0032 16.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3678) R3H PF01424.22 OAI99828.1 - 1.5e-12 47.3 0.0 3.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain PfkB PF00294.24 OAI99840.1 - 0.001 18.4 1.2 0.019 14.3 0.6 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Fasciclin PF02469.22 OAI99841.1 - 3.4e-06 27.3 0.0 1.5e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Fasciclin domain Rep_fac_C PF08542.11 OAI99841.1 - 0.019 15.4 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Replication factor C C-terminal domain zf-RING_2 PF13639.6 OAI99869.1 - 2.3e-08 34.2 6.0 8e-07 29.3 0.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OAI99869.1 - 6e-06 26.0 5.6 6.8e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAI99869.1 - 3e-05 23.8 3.0 0.00046 20.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAI99869.1 - 4e-05 23.8 0.1 4e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAI99869.1 - 8.3e-05 22.4 0.5 8.3e-05 22.4 0.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAI99869.1 - 0.00018 21.1 0.8 0.00036 20.1 0.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OAI99869.1 - 0.00021 21.1 2.6 0.00067 19.6 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAI99869.1 - 0.0046 16.8 4.2 0.0087 15.9 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAI99869.1 - 0.0082 16.2 12.7 0.0088 16.1 1.9 2.8 2 1 1 3 3 3 1 RING-type zinc-finger Spt20 PF12090.8 OAI99869.1 - 0.01 15.5 5.6 0.01 15.5 5.6 1.9 2 0 0 2 2 2 0 Spt20 family RAB3GAP2_N PF14655.6 OAI99869.1 - 0.025 13.8 1.2 0.04 13.2 1.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-ANAPC11 PF12861.7 OAI99869.1 - 0.041 13.9 0.2 0.041 13.9 0.2 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAI99869.1 - 0.05 13.3 3.3 0.73 9.6 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 OAI99869.1 - 0.064 13.6 0.3 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 OAI99869.1 - 0.22 11.4 1.3 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OAI99869.1 - 0.36 11.0 7.8 0.37 11.0 3.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain LIM_bind PF01803.16 OAI99869.1 - 0.5 9.9 2.9 3.5 7.1 0.1 2.3 2 0 0 2 2 2 0 LIM-domain binding protein Rad50_zn_hook PF04423.14 OAI99869.1 - 1.1 9.2 4.3 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif TetR_C_21 PF17926.1 OAI99869.1 - 1.2 9.3 6.8 1.7 8.8 0.2 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TMEM132D_C PF15706.5 OAI99869.1 - 2.5 7.9 3.6 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RINGv PF12906.7 OAI99869.1 - 3.8 7.7 6.8 0.37 10.9 1.5 2.0 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 OAI99869.1 - 4.5 7.5 7.8 1 9.6 0.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4834 PF16118.5 OAI99869.1 - 5.6 8.0 7.7 43 5.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Sugar_tr PF00083.24 OAI99883.1 - 6.7e-102 341.7 18.3 8e-102 341.4 18.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAI99883.1 - 2e-24 86.2 25.2 2e-23 82.9 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CAP_N PF01213.19 OAI99893.1 - 2.1 7.8 0.0 2.1 7.8 0.0 2.9 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DUF2062 PF09835.9 OAI99899.1 - 2.1e-05 24.4 2.1 2.7e-05 24.1 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Syntaxin-6_N PF09177.11 OAI99902.1 - 0.00091 19.7 4.2 0.0015 19.1 4.2 1.4 1 0 0 1 1 1 1 Syntaxin 6, N-terminal DUF2397 PF09660.10 OAI99902.1 - 0.0018 17.3 1.2 0.0018 17.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) Fez1 PF06818.15 OAI99902.1 - 0.0077 16.7 5.6 0.011 16.2 5.6 1.2 1 0 0 1 1 1 1 Fez1 DUF2408 PF10303.9 OAI99902.1 - 0.0081 16.7 3.3 0.0088 16.6 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Dor1 PF04124.12 OAI99902.1 - 0.019 13.7 2.0 0.021 13.5 2.0 1.1 1 0 0 1 1 1 0 Dor1-like family SLX9 PF15341.6 OAI99902.1 - 0.044 14.2 4.5 0.062 13.7 4.5 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Seryl_tRNA_N PF02403.22 OAI99902.1 - 0.052 13.8 6.4 0.066 13.4 6.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CCDC106 PF15794.5 OAI99902.1 - 0.054 13.2 4.2 0.056 13.1 4.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TPR_MLP1_2 PF07926.12 OAI99902.1 - 0.08 13.0 7.1 0.13 12.4 7.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FemAB PF02388.16 OAI99902.1 - 0.11 11.3 3.4 0.14 11.0 3.4 1.1 1 0 0 1 1 1 0 FemAB family DUF2205 PF10224.9 OAI99902.1 - 0.13 12.3 4.6 0.25 11.4 3.1 2.2 1 1 1 2 2 2 0 Short coiled-coil protein DUF3734 PF12536.8 OAI99902.1 - 0.16 12.4 3.1 0.26 11.6 3.0 1.4 1 1 0 1 1 1 0 Patatin phospholipase Peptidase_S49_N PF08496.10 OAI99902.1 - 0.19 11.8 5.6 0.24 11.5 5.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nup88 PF10168.9 OAI99902.1 - 0.28 8.9 4.4 0.28 8.9 4.4 1.0 1 0 0 1 1 1 0 Nuclear pore component FlxA PF14282.6 OAI99902.1 - 0.29 11.1 7.0 0.45 10.5 7.0 1.3 1 0 0 1 1 1 0 FlxA-like protein Ax_dynein_light PF10211.9 OAI99902.1 - 0.35 10.8 8.4 0.41 10.6 8.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain UPF0242 PF06785.11 OAI99902.1 - 0.44 10.6 5.9 0.52 10.4 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OAI99902.1 - 0.51 9.4 5.3 0.54 9.3 5.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 OAI99902.1 - 0.6 10.4 7.1 0.84 9.9 7.1 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 OAI99902.1 - 0.88 8.9 4.2 1.1 8.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 OAI99902.1 - 2.8 8.6 8.1 2.5 8.8 2.0 2.5 1 1 1 2 2 2 0 SlyX Neurokinin_B PF03823.14 OAI99914.1 - 0.11 12.6 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Neurokinin B DUF5552 PF17706.1 OAI99929.1 - 0.06 13.1 0.2 0.12 12.1 0.1 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5552) HALZ PF02183.18 OAI99948.1 - 0.0014 18.8 0.3 0.002 18.3 0.3 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper CDH-cyt PF16010.5 OAI99962.1 - 6.9e-13 48.7 5.4 1.1e-12 48.0 5.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAI99962.1 - 2.1e-08 34.4 9.9 4.2e-08 33.4 9.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAI99962.1 - 4.5e-05 23.7 1.2 0.0001 22.5 0.9 1.8 1 1 1 2 2 2 1 DOMON domain DUF2427 PF10348.9 OAI99962.1 - 0.055 13.3 4.5 0.23 11.3 4.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Vps16_C PF04840.12 OAI99995.1 - 8.9e-71 238.5 1.7 3.6e-38 131.4 0.0 3.1 3 0 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.13 OAI99995.1 - 1.2e-34 119.8 0.0 9.7e-21 74.0 0.0 3.1 3 0 0 3 3 3 3 Vps16, N-terminal region RVT_1 PF00078.27 OAJ00013.1 - 3.1e-23 82.4 0.0 5e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ00013.1 - 0.00019 22.0 0.0 0.00045 20.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ00013.1 - 0.001 19.6 0.0 0.0031 18.0 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ00013.1 - 0.1 12.9 0.0 0.36 11.2 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease 4HBT_3 PF13622.6 OAJ00028.1 - 9.3e-32 111.2 0.2 1.4e-31 110.7 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ00028.1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA thioesterase DPBB_1 PF03330.18 OAJ00029.1 - 1.5e-06 28.4 1.4 1.7e-06 28.2 0.1 1.9 2 1 0 2 2 2 1 Lytic transglycolase eIF3_subunit PF08597.10 OAJ00029.1 - 0.00066 19.7 3.7 0.001 19.1 3.7 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Barwin PF00967.17 OAJ00029.1 - 0.0056 16.5 1.0 0.013 15.4 1.0 1.6 1 0 0 1 1 1 1 Barwin family TonB_N PF16031.5 OAJ00029.1 - 0.89 10.1 25.1 2.1 8.9 25.1 1.6 1 0 0 1 1 1 0 TonB polyproline region TraT PF05818.12 OAJ00029.1 - 1.2 8.8 8.2 2.6 7.7 8.2 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein ATG16 PF08614.11 OAJ00029.1 - 1.6 8.9 6.2 2.2 8.5 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Trypan_PARP PF05887.11 OAJ00029.1 - 3.3 7.7 16.1 7.1 6.6 15.9 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Apt1 PF10351.9 OAJ00029.1 - 4.3 6.1 10.7 5.7 5.7 10.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HEAT_2 PF13646.6 OAJ00077.1 - 6e-06 26.6 1.1 1.1e-05 25.7 1.1 1.4 1 0 0 1 1 1 1 HEAT repeats DUF3492 PF11997.8 OAJ00079.1 - 1.1e-89 300.8 0.0 1.3e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glycos_transf_1 PF00534.20 OAJ00079.1 - 2.1e-19 69.7 0.0 3.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ00079.1 - 1.1e-18 67.9 0.1 3.1e-18 66.5 0.3 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ00079.1 - 6.3e-06 26.3 0.1 1.9e-05 24.8 0.1 1.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAJ00079.1 - 0.0015 19.0 1.4 0.0026 18.2 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain UBA PF00627.31 OAJ00094.1 - 2.4e-05 24.1 0.0 7.2e-05 22.6 0.0 1.8 2 0 0 2 2 1 1 UBA/TS-N domain MscS_porin PF12795.7 OAJ00094.1 - 0.029 13.9 8.3 0.049 13.2 8.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 OAJ00094.1 - 0.081 13.1 11.5 0.27 11.4 11.5 2.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MAD PF05557.13 OAJ00094.1 - 0.096 11.0 10.8 0.14 10.5 10.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Tup_N PF08581.10 OAJ00094.1 - 0.15 12.4 0.3 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 Tup N-terminal zf-C4H2 PF10146.9 OAJ00094.1 - 0.18 12.1 0.8 0.38 11.0 0.8 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein FliJ PF02050.16 OAJ00094.1 - 0.24 11.6 4.9 0.12 12.6 2.3 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein HOIP-UBA PF16678.5 OAJ00094.1 - 0.26 11.3 4.5 7.6 6.5 3.5 2.3 2 0 0 2 2 2 0 HOIP UBA domain pair Alpha-2-MRAP_C PF06401.11 OAJ00094.1 - 0.27 11.2 1.6 0.47 10.4 1.6 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF2353 PF09789.9 OAJ00094.1 - 0.47 9.8 8.6 0.72 9.2 8.6 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4407 PF14362.6 OAJ00094.1 - 0.73 9.1 6.1 1.5 8.1 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1640 PF07798.11 OAJ00094.1 - 0.91 9.5 5.7 1.7 8.6 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GAS PF13851.6 OAJ00094.1 - 1.3 8.4 9.2 2.2 7.6 9.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 OAJ00094.1 - 1.3 9.7 3.6 11 6.7 3.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Fez1 PF06818.15 OAJ00094.1 - 1.4 9.3 10.5 2.2 8.7 10.5 1.3 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 OAJ00094.1 - 1.5 8.9 5.1 3.4 7.7 5.1 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 OAJ00094.1 - 2.7 7.4 9.9 4.1 6.8 9.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 YscO PF07321.12 OAJ00094.1 - 3 7.8 14.9 5.9 6.8 14.9 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO DUF4472 PF14739.6 OAJ00094.1 - 3.5 8.4 7.0 2.1 9.1 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Spc7 PF08317.11 OAJ00094.1 - 3.5 6.4 10.8 1.4 7.7 8.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 OAJ00094.1 - 3.9 7.8 5.9 8.6 6.7 0.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 OAJ00094.1 - 6.6 6.8 16.1 1.6 8.7 7.9 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KH_1 PF00013.29 OAJ00131.1 - 9.8e-09 34.9 0.0 0.00013 21.7 0.0 2.6 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 OAJ00131.1 - 0.043 14.0 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein DUF4218 PF13960.6 OAJ00147.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Histone PF00125.24 OAJ00149.1 - 3.4e-45 153.6 2.8 3.8e-45 153.4 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ00149.1 - 3.5e-05 23.9 0.7 4.9e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ00149.1 - 3.5e-05 24.1 0.0 5.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAJ00149.1 - 0.00039 20.6 0.1 0.00077 19.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ00149.1 - 0.0041 17.2 0.1 0.0071 16.4 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PAF PF15715.5 OAJ00149.1 - 0.02 15.4 1.0 0.028 15.0 1.0 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain HisKA PF00512.25 OAJ00149.1 - 0.051 13.6 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DNA_pol_phi PF04931.13 OAJ00155.1 - 6.2e-135 451.2 7.5 5.7e-134 448.0 7.5 2.1 1 1 0 1 1 1 1 DNA polymerase phi HEAT PF02985.22 OAJ00155.1 - 0.073 13.4 0.5 21 5.7 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat RRN3 PF05327.11 OAJ00155.1 - 0.13 10.8 13.4 0.67 8.4 12.4 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SET PF00856.28 OAJ00155.1 - 2.8 8.3 6.1 5.8 7.3 0.1 2.9 3 0 0 3 3 3 0 SET domain Trypan_PARP PF05887.11 OAJ00155.1 - 3.9 7.5 13.0 21 5.1 13.0 2.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRM_1 PF00076.22 OAJ00172.1 - 1.2e-79 262.1 1.6 6.7e-19 67.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAJ00172.1 - 2.6e-26 91.6 0.5 3.9e-25 87.8 0.2 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAJ00172.1 - 7.5e-09 35.2 0.6 0.33 10.5 0.0 4.2 2 1 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ00172.1 - 2.3e-07 30.7 1.1 0.11 12.5 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ00172.1 - 0.00011 22.3 0.2 9.2 6.5 0.0 4.9 3 2 1 4 4 4 2 RNA recognition motif YflT PF11181.8 OAJ00172.1 - 0.0051 17.3 0.8 0.72 10.4 0.3 2.8 2 0 0 2 2 2 1 Heat induced stress protein YflT DUF4523 PF15023.6 OAJ00172.1 - 0.034 14.0 0.0 3.8 7.3 0.0 3.4 2 2 1 4 4 4 0 Protein of unknown function (DUF4523) Nefa_Nip30_N PF10187.9 OAJ00172.1 - 0.036 14.4 1.3 0.036 14.4 1.3 3.6 4 0 0 4 4 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Trimer_CC PF08954.11 OAJ00186.1 - 0.15 11.6 0.5 0.54 9.8 0.5 1.9 1 0 0 1 1 1 0 Trimerisation motif PQ-loop PF04193.14 OAJ00202.1 - 2.5e-13 49.6 0.1 5.5e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 PQ loop repeat AMP-binding PF00501.28 OAJ00214.1 - 1.9e-20 72.8 0.5 1.1e-18 67.1 0.5 2.5 2 1 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ00214.1 - 2e-12 46.8 0.0 4.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ00214.1 - 2e-08 34.0 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ00214.1 - 0.0047 16.9 0.0 0.024 14.6 0.0 2.2 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 OAJ00214.1 - 0.073 13.4 0.0 0.74 10.2 0.0 2.4 1 1 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 OAJ00214.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_2 PF07719.17 OAJ00228.1 - 3.1e-07 30.0 0.7 8.1e-05 22.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ00228.1 - 2.8e-06 26.9 0.9 0.00021 21.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ00228.1 - 0.0064 16.2 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 OAJ00228.1 - 0.018 15.2 0.2 0.076 13.3 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ00228.1 - 0.02 15.0 0.0 0.02 15.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Med3 PF11593.8 OAJ00228.1 - 0.044 13.0 5.8 0.054 12.7 5.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4523 PF15023.6 OAJ00228.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) TPR_19 PF14559.6 OAJ00229.1 - 3.2e-06 27.5 0.9 0.029 14.9 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ00229.1 - 4.1e-05 24.1 6.0 0.12 13.1 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ00229.1 - 9.9e-05 22.2 0.0 0.012 15.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ00229.1 - 0.00078 19.9 0.5 0.022 15.4 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ00229.1 - 0.0032 17.7 0.1 0.28 11.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ00229.1 - 0.0045 17.7 4.1 0.48 11.4 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ00229.1 - 0.0075 16.1 0.8 0.067 13.1 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ00229.1 - 0.023 15.3 0.1 2 9.3 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 OAJ00229.1 - 0.1 12.8 0.4 15 5.9 0.0 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.28 OAJ00229.1 - 0.15 12.0 0.0 5.7 6.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Thaumatin PF00314.17 OAJ00244.1 - 1.5e-17 64.0 3.6 2.4e-17 63.3 3.0 1.5 1 1 1 2 2 2 2 Thaumatin family adh_short_C2 PF13561.6 OAJ00274.1 - 4.9e-23 81.9 0.0 2e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ00274.1 - 2.9e-07 30.1 0.0 0.0002 20.8 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_23 PF13489.6 OAJ00275.1 - 1.1e-15 57.8 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ00275.1 - 0.003 17.4 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ00275.1 - 0.03 15.1 0.0 0.1 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ00275.1 - 0.063 13.9 0.0 0.48 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_21 PF05050.12 OAJ00276.1 - 3.9e-15 56.3 0.0 6.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 OAJ00276.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein V_cholerae_RfbT PF05575.11 OAJ00276.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_4 PF02390.17 OAJ00276.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Epimerase PF01370.21 OAJ00277.1 - 1.4e-38 132.7 0.0 1.8e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ00277.1 - 2e-23 83.3 0.0 3.4e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAJ00277.1 - 1.7e-08 33.9 0.0 7.7e-06 25.3 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAJ00277.1 - 8.8e-06 25.0 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAJ00277.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAJ00277.1 - 0.017 14.3 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_trans_2_3 PF13632.6 OAJ00293.1 - 2.7e-05 24.2 0.1 3.6e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Mucin PF01456.17 OAJ00313.1 - 0.00019 21.4 25.7 0.00019 21.4 25.7 3.3 3 0 0 3 3 3 1 Mucin-like glycoprotein MGC-24 PF05283.11 OAJ00313.1 - 0.0042 17.5 8.2 0.0042 17.5 8.2 3.5 4 0 0 4 4 4 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2207 PF09972.9 OAJ00313.1 - 0.063 12.0 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CKS PF01111.19 OAJ00332.1 - 1.4e-35 121.4 0.1 1.7e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ATP-synt_10 PF05176.14 OAJ00333.1 - 5.4e-45 153.6 0.0 8.5e-30 103.8 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein Ras PF00071.22 OAJ00334.1 - 1.2e-56 190.8 0.0 1.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ00334.1 - 5.6e-35 120.2 0.1 7.8e-35 119.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ00334.1 - 1.3e-16 60.6 0.0 1.1e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ00334.1 - 6.9e-06 25.6 0.0 9.1e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ00334.1 - 0.00015 21.4 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ00334.1 - 0.00027 21.0 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ00334.1 - 0.0026 18.1 0.3 0.0051 17.2 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ00334.1 - 0.057 13.3 0.0 10 6.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase Cu-oxidase_3 PF07732.15 OAJ00356.1 - 1.3e-26 93.0 3.5 1.3e-25 89.7 0.2 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAJ00356.1 - 3.8e-15 56.3 0.0 8.1e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ00356.1 - 6.7e-15 55.0 8.7 6.3e-11 42.2 2.6 3.6 2 2 0 2 2 2 2 Multicopper oxidase Ndufs5 PF10200.9 OAJ00375.1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa MIP PF00230.20 OAJ00376.1 - 1e-08 35.1 8.2 1.7e-08 34.4 8.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF4449 PF14613.6 OAJ00392.1 - 0.00043 20.4 8.4 0.015 15.4 0.0 4.0 3 2 0 3 3 3 2 Protein of unknown function (DUF4449) Phage_tail_U PF06141.11 OAJ00392.1 - 0.0053 17.1 0.5 0.46 10.9 0.6 2.8 2 0 0 2 2 2 1 Phage minor tail protein U DASH_Duo1 PF08651.10 OAJ00392.1 - 0.025 14.3 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 Nif11 PF07862.11 OAJ00392.1 - 0.1 12.9 1.5 1.1 9.6 0.0 3.5 3 0 0 3 3 3 0 Nif11 domain Laminin_I PF06008.14 OAJ00392.1 - 0.33 10.6 7.1 2.9 7.5 1.9 3.4 3 0 0 3 3 3 0 Laminin Domain I DUF445 PF04286.12 OAJ00392.1 - 1.6 8.4 14.2 24 4.6 13.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DDE_1 PF03184.19 OAJ00407.1 - 2.5e-16 59.8 0.0 9.5e-16 57.9 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OAJ00407.1 - 0.012 15.4 2.7 1.4 8.7 0.0 3.4 3 0 0 3 3 3 0 DDE superfamily endonuclease CDC45 PF02724.14 OAJ00407.1 - 5.3 5.2 15.2 7.2 4.8 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_3 PF13358.6 OAJ00420.1 - 1.5e-27 96.1 0.0 2.1e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ00420.1 - 0.0013 19.3 0.0 0.0034 18.0 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OAJ00420.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.6 OAJ00420.1 - 0.005 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 OAJ00420.1 - 0.082 13.0 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Glyco_hydro_18 PF00704.28 OAJ00442.1 - 5.2e-38 131.5 0.0 6.3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_1 PF00133.22 OAJ00463.1 - 3.9e-107 359.0 0.0 5.2e-107 358.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ00463.1 - 7.1e-22 78.0 0.0 1.4e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ00463.1 - 5.5e-06 25.4 0.0 0.0036 16.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAJ00463.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CK2S PF15011.6 OAJ00464.1 - 0.095 12.6 0.1 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Casein Kinase 2 substrate zf-C4H2 PF10146.9 OAJ00481.1 - 0.014 15.7 0.5 0.032 14.6 0.5 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein SKA1 PF07160.12 OAJ00481.1 - 0.056 13.3 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CCDC53 PF10152.9 OAJ00481.1 - 0.53 10.7 3.4 5.3 7.4 3.4 2.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex zf-CCHC PF00098.23 OAJ00516.1 - 0.027 14.5 7.4 0.054 13.6 7.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ00516.1 - 0.093 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TPK_B1_binding PF04265.14 OAJ00534.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain WW PF00397.26 OAJ00607.1 - 2.8e-09 36.9 1.4 0.00038 20.5 0.1 2.5 2 0 0 2 2 2 2 WW domain Cation_efflux PF01545.21 OAJ00631.1 - 6.2e-27 94.6 4.8 6.2e-27 94.6 4.8 2.9 3 1 0 3 3 3 1 Cation efflux family DHHC PF01529.20 OAJ00631.1 - 2 8.5 3.9 2.1 8.5 0.2 2.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF1713 PF08213.11 OAJ00632.1 - 2.7e-10 40.0 25.0 4.4e-10 39.3 25.0 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) CDK2AP PF09806.9 OAJ00632.1 - 0.0064 16.6 3.4 0.009 16.1 3.4 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Protamine_P2 PF00841.19 OAJ00632.1 - 0.081 13.4 9.9 0.15 12.5 9.9 1.5 1 0 0 1 1 1 0 Sperm histone P2 Pex26 PF07163.12 OAJ00632.1 - 1.2 8.3 10.3 0.16 11.2 5.2 1.8 2 0 0 2 2 2 0 Pex26 protein RT_RNaseH_2 PF17919.1 OAJ00656.1 - 1.6e-23 82.6 0.0 1.6e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ00656.1 - 2.5e-21 76.2 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ00656.1 - 7.3e-17 61.6 0.0 8.3e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ00656.1 - 4.6e-12 46.2 0.0 1.3e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ00656.1 - 5.9e-10 39.1 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Calcipressin PF04847.12 OAJ00671.1 - 0.098 12.4 0.6 0.2 11.4 0.6 1.5 1 0 0 1 1 1 0 Calcipressin GATase_4 PF13230.6 OAJ00690.1 - 2.7e-17 62.6 0.0 1.3e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAJ00690.1 - 2.6e-09 37.4 0.0 6.3e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Chromo PF00385.24 OAJ00692.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 OAJ00709.1 - 3.8e-67 226.4 0.0 4.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ00709.1 - 1.4e-33 116.3 0.0 4.5e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ00709.1 - 0.001 18.4 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ00709.1 - 0.0043 16.1 0.1 0.0066 15.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ00709.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ00709.1 - 0.09 12.7 0.1 0.26 11.2 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ00709.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 OAJ00709.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RVT_1 PF00078.27 OAJ00748.1 - 0.00076 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAJ00774.1 - 0.0085 15.5 0.1 0.026 13.9 0.1 2.0 2 1 0 2 2 2 1 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAJ00774.1 - 0.013 15.3 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.27 OAJ00774.1 - 0.032 13.7 0.0 0.09 12.3 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 OAJ00775.1 - 0.00035 20.4 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family TFIIA PF03153.13 OAJ00795.1 - 0.0002 21.5 11.7 0.0002 21.5 11.7 2.3 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit TRAM_LAG1_CLN8 PF03798.16 OAJ00795.1 - 0.00048 19.9 10.3 0.00083 19.1 10.3 1.4 1 0 0 1 1 1 1 TLC domain BORA_N PF15280.6 OAJ00813.1 - 0.061 13.0 0.7 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein aurora borealis N-terminus fn3_5 PF06280.12 OAJ00815.1 - 6.3e-11 43.0 0.0 9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Fn3-like domain ASH PF15780.5 OAJ00815.1 - 0.043 14.0 0.0 1.1 9.5 0.0 2.2 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GLE1 PF07817.13 OAJ00837.1 - 1.9e-71 240.3 0.0 2.8e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein eIF3_subunit PF08597.10 OAJ00837.1 - 0.0015 18.5 17.2 0.0033 17.4 17.2 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit V_ATPase_I PF01496.19 OAJ00837.1 - 0.23 9.4 4.9 0.28 9.0 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPP4R2 PF09184.11 OAJ00837.1 - 0.32 10.5 15.5 8.8 5.8 0.0 2.5 2 0 0 2 2 2 0 PPP4R2 DUF4407 PF14362.6 OAJ00837.1 - 2 7.7 14.7 3.6 6.9 14.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4746 PF15928.5 OAJ00837.1 - 2.9 7.2 15.2 5.1 6.4 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PA26 PF04636.13 OAJ00837.1 - 6.6 5.5 6.7 10 4.9 6.7 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Snf7 PF03357.21 OAJ00838.1 - 2.5e-10 40.2 10.7 2.9e-10 40.0 10.7 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 OAJ00838.1 - 0.0036 16.9 0.3 0.0065 16.1 0.0 1.4 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase SYCE1 PF15233.6 OAJ00838.1 - 0.0044 17.1 2.3 0.0062 16.6 2.3 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 FKBP_C PF00254.28 OAJ00838.1 - 0.096 13.0 0.1 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase YlqD PF11068.8 OAJ00838.1 - 0.16 12.4 5.9 0.24 11.8 1.2 2.1 1 1 0 2 2 2 0 YlqD protein ABC1 PF03109.16 OAJ00859.1 - 3.1e-25 88.7 0.0 5.6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.9 OAJ00859.1 - 2.7e-17 62.1 2.0 7e-17 60.8 2.0 1.8 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 OAJ00859.1 - 0.48 10.4 3.2 1 9.4 3.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Dimer_Tnp_hAT PF05699.14 OAJ00880.1 - 4.3e-12 45.7 0.0 1.7e-11 43.7 0.0 2.0 1 1 1 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ00880.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Sec23_helical PF04815.15 OAJ00904.1 - 5.2e-24 84.0 0.7 8.4e-24 83.4 0.7 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 OAJ00904.1 - 1.1e-08 34.8 0.0 3.2e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat DUF3429 PF11911.8 OAJ00905.1 - 3.6e-39 134.3 16.6 5.8e-39 133.7 16.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) MULE PF10551.9 OAJ00930.1 - 4.3e-12 46.3 0.4 3e-07 30.8 0.2 2.5 1 1 1 2 2 2 2 MULE transposase domain HsbA PF12296.8 OAJ00945.1 - 2.1e-17 63.7 15.9 2.1e-17 63.7 15.9 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A RVT_N PF13655.6 OAJ00945.1 - 0.1 12.9 1.6 4.8 7.5 0.1 2.3 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase bZIP_1 PF00170.21 OAJ00968.1 - 1.4e-07 31.5 4.7 1.4e-07 31.5 4.7 2.2 2 1 0 2 2 2 1 bZIP transcription factor UCR_14kD PF02271.16 OAJ00968.1 - 0.07 13.1 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit bZIP_2 PF07716.15 OAJ00968.1 - 0.19 11.8 8.8 0.38 10.9 4.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper FA_desaturase PF00487.24 OAJ00969.1 - 1.7e-11 44.4 6.7 2.6e-11 43.8 6.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF2083 PF09856.9 OAJ00969.1 - 0.078 12.8 0.4 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Predicted transcriptional regulator (DUF2083) DDE_Tnp_4 PF13359.6 OAJ00993.1 - 8.7e-23 80.7 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Asp PF00026.23 OAJ01019.1 - 5.6e-37 127.8 0.0 2.6e-36 125.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ01019.1 - 2.2e-12 47.6 0.1 7.3e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DUF3989 PF13150.6 OAJ01042.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) RVT_1 PF00078.27 OAJ01064.1 - 5.4e-24 84.9 0.0 9.8e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ01064.1 - 1.7e-20 72.9 0.1 4.2e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ01064.1 - 1.5e-14 53.8 0.0 4e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ01064.1 - 2e-13 50.5 0.0 5.5e-09 36.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ01064.1 - 3.2e-10 40.3 0.0 1.4e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ01064.1 - 0.0001 22.4 0.0 0.023 14.9 0.0 2.8 2 0 0 2 2 2 1 H2C2 zinc finger Aa_trans PF01490.18 OAJ01105.1 - 1.6e-85 287.3 5.7 2e-85 287.0 5.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ResIII PF04851.15 OAJ01127.1 - 8.5e-19 68.2 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ01127.1 - 5.7e-12 45.8 0.0 9.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ01127.1 - 5.1e-11 42.9 0.0 1.3e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 OAJ01127.1 - 0.00031 21.2 0.0 0.0011 19.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 OAJ01127.1 - 0.0022 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAJ01127.1 - 0.003 17.9 0.0 0.0069 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ01127.1 - 0.0037 17.1 3.0 1.7 8.3 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 OAJ01127.1 - 0.01 16.1 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ01127.1 - 0.017 14.8 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Helicase_C PF00271.31 OAJ01129.1 - 8.5e-08 32.5 0.0 2.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 OAJ01129.1 - 0.061 13.5 0.5 0.66 10.1 0.0 2.4 2 1 0 3 3 3 0 Helicase C-terminal domain RecQ_Zn_bind PF16124.5 OAJ01129.1 - 0.38 11.5 0.0 0.38 11.5 0.0 2.8 2 1 0 2 2 2 0 RecQ zinc-binding Eapp_C PF10238.9 OAJ01129.1 - 0.5 10.4 4.7 0.77 9.8 3.8 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein Presenilin PF01080.17 OAJ01129.1 - 0.73 8.5 4.1 1.1 8.0 4.1 1.2 1 0 0 1 1 1 0 Presenilin DUF755 PF05501.11 OAJ01129.1 - 2.4 8.4 13.3 1.4 9.2 10.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Rrn6 PF10214.9 OAJ01129.1 - 6.4 5.1 12.0 9.7 4.5 12.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRN3 PF05327.11 OAJ01129.1 - 7 5.1 7.5 0.59 8.6 2.7 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_3 PF13456.6 OAJ01155.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like YgaB PF14182.6 OAJ01155.1 - 1 9.8 3.4 2.3 8.7 3.4 1.5 1 0 0 1 1 1 0 YgaB-like protein DUF2236 PF09995.9 OAJ01193.1 - 2.6e-28 99.8 0.9 2.6e-28 99.8 0.9 2.2 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2236) Ysc84 PF04366.12 OAJ01215.1 - 2.7e-42 143.5 1.7 6.7e-41 139.0 0.2 2.1 2 0 0 2 2 2 2 Las17-binding protein actin regulator zf-CCHC PF00098.23 OAJ01235.1 - 0.00037 20.4 0.5 0.00054 19.9 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ01235.1 - 0.0022 17.9 1.4 0.0023 17.9 0.6 1.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ01235.1 - 0.024 14.3 0.3 0.052 13.3 0.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH PF17917.1 OAJ01236.1 - 3.3e-33 114.1 0.0 7e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ01236.1 - 3.2e-32 110.5 0.0 1.2e-31 108.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ01236.1 - 9.1e-19 67.3 0.1 1.9e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ01236.1 - 1.5e-12 47.8 0.0 4.7e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ01236.1 - 8.5e-11 41.8 0.1 7.6e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ01236.1 - 1.9e-05 24.4 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OAJ01236.1 - 0.00038 21.1 0.0 0.00084 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ01236.1 - 0.0013 19.2 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ01236.1 - 0.008 16.4 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger NMO PF03060.15 OAJ01278.1 - 3.6e-51 174.5 3.2 5.2e-51 174.0 3.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAJ01278.1 - 1.9e-07 30.4 6.5 1.3e-06 27.7 6.5 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAJ01278.1 - 0.00017 20.7 2.7 0.00033 19.8 2.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IF2_N PF04760.15 OAJ01278.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FAA_hydrolase PF01557.18 OAJ01279.1 - 1.8e-56 191.2 0.0 2.1e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TANGO2 PF05742.12 OAJ01297.1 - 1.3e-36 127.0 0.0 1.7e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Transport and Golgi organisation 2 RcsD_ABL PF16359.5 OAJ01297.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 RcsD-ABL domain Sad1_UNC PF07738.13 OAJ01298.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal RT_RNaseH PF17917.1 OAJ01321.1 - 1.9e-13 50.6 0.0 2.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ01321.1 - 3.3e-08 33.5 0.0 4.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF659 PF04937.15 OAJ01322.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) CNH PF00780.22 OAJ01322.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 CNH domain SpoIIIAH PF12685.7 OAJ01322.1 - 0.28 11.0 5.0 0.46 10.3 5.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 OAJ01322.1 - 0.62 8.2 9.9 0.8 7.8 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ01322.1 - 0.9 8.8 12.1 1.3 8.3 12.1 1.1 1 0 0 1 1 1 0 BUD22 NDC10_II PF16787.5 OAJ01325.1 - 8.5e-09 34.9 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RAP1 PF07218.11 OAJ01377.1 - 5 5.3 8.5 5.7 5.1 8.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.12 OAJ01377.1 - 6.6 5.0 7.4 7.9 4.8 7.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) YL1 PF05764.13 OAJ01378.1 - 2.9e-05 24.3 7.6 4e-05 23.9 7.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAJ01378.1 - 0.00018 19.9 3.9 0.00018 19.9 3.9 1.1 1 0 0 1 1 1 1 CDC45-like protein PTPRCAP PF15713.5 OAJ01378.1 - 0.0004 20.7 8.3 0.00049 20.4 8.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 OAJ01378.1 - 0.17 10.6 9.5 0.17 10.6 9.5 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 OAJ01378.1 - 0.21 11.1 13.9 0.27 10.8 13.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 OAJ01378.1 - 0.23 10.9 5.6 0.31 10.4 5.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 OAJ01378.1 - 0.23 10.8 5.1 0.25 10.7 5.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Roughex PF06020.11 OAJ01378.1 - 0.25 10.4 12.4 0.34 10.0 12.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein eIF-3_zeta PF05091.12 OAJ01378.1 - 0.33 9.9 9.5 0.41 9.6 9.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 OAJ01378.1 - 0.44 10.7 5.3 0.79 9.9 5.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Apt1 PF10351.9 OAJ01378.1 - 0.45 9.3 7.2 0.52 9.1 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt5_N PF11942.8 OAJ01378.1 - 0.65 11.0 15.7 1.2 10.2 15.7 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal eIF3_subunit PF08597.10 OAJ01378.1 - 0.75 9.7 12.5 1.1 9.2 12.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SLC12 PF03522.15 OAJ01378.1 - 0.85 8.6 5.5 0.9 8.5 5.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 OAJ01378.1 - 1.3 7.4 5.4 1.5 7.2 5.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Connexin PF00029.19 OAJ01378.1 - 1.6 8.5 3.8 2 8.1 3.8 1.2 1 0 0 1 1 1 0 Connexin DUF853 PF05872.12 OAJ01378.1 - 1.9 7.0 5.9 2.6 6.5 5.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Rrn6 PF10214.9 OAJ01378.1 - 2.1 6.7 20.2 2.6 6.4 20.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor U79_P34 PF03064.16 OAJ01378.1 - 2.5 7.4 12.3 3.5 6.9 12.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.12 OAJ01378.1 - 3.1 7.6 14.6 5 6.9 14.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 OAJ01378.1 - 4.1 6.9 24.2 5.6 6.5 24.2 1.1 1 0 0 1 1 1 0 Spt20 family SelP_N PF04592.14 OAJ01378.1 - 5 6.5 11.0 8.6 5.7 11.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NARP1 PF12569.8 OAJ01378.1 - 5.8 5.7 10.3 7.4 5.4 10.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAT1 PF09770.9 OAJ01378.1 - 6.4 4.9 19.7 7.3 4.7 19.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 OAJ01378.1 - 9.5 3.2 10.3 10 3.1 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Merozoite_SPAM PF07133.11 OAJ01378.1 - 10 6.1 17.9 14 5.6 17.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SRI PF08236.11 OAJ01402.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Dimer_Tnp_hAT PF05699.14 OAJ01442.1 - 1.4e-13 50.4 0.0 3.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Histone PF00125.24 OAJ01443.1 - 2.3e-18 66.8 0.0 3.9e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bac_rhamnosid PF05592.11 OAJ01443.1 - 0.17 11.9 0.2 0.27 11.2 0.2 1.5 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain SR-25 PF10500.9 OAJ01469.1 - 0.003 17.2 15.9 0.003 17.2 15.9 3.0 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein SEEEED PF14797.6 OAJ01469.1 - 0.012 15.8 23.4 0.012 15.8 23.4 3.4 3 0 0 3 3 3 0 Serine-rich region of AP3B1, clathrin-adaptor complex CDK2AP PF09806.9 OAJ01469.1 - 8 6.5 11.2 2.2 8.3 2.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein RT_RNaseH_2 PF17919.1 OAJ01493.1 - 0.0011 19.0 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ01493.1 - 0.049 13.9 0.0 1.9 8.8 0.0 2.6 1 1 1 2 2 2 0 RNase H-like domain found in reverse transcriptase TPR_10 PF13374.6 OAJ01535.1 - 9.6e-10 38.0 8.0 0.00047 19.9 0.0 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ01535.1 - 4.7e-07 30.0 9.8 0.0097 16.2 0.3 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ01535.1 - 0.0033 17.4 10.6 11 6.4 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ01535.1 - 0.081 13.8 12.0 35 5.6 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat SLT_2 PF13406.6 OAJ01535.1 - 0.16 11.2 2.1 0.52 9.5 0.0 2.6 3 0 0 3 3 3 0 Transglycosylase SLT domain TPR_6 PF13174.6 OAJ01535.1 - 0.89 10.3 4.6 20 6.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ELFV_dehydrog_N PF02812.18 OAJ01538.1 - 4.2e-47 159.3 0.0 5.7e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NPV_P10 PF05531.12 OAJ01586.1 - 0.00035 21.0 0.1 0.00085 19.7 0.1 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DDE_3 PF13358.6 OAJ01586.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease An_peroxidase PF03098.15 OAJ01606.1 - 2.8e-05 22.9 0.0 3.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase rRNA_processing PF08524.11 OAJ01645.1 - 0.0036 17.3 29.7 2.3 8.2 12.6 3.3 2 1 1 3 3 3 2 rRNA processing SDA1 PF05285.12 OAJ01646.1 - 0.0011 18.5 8.6 0.0016 18.0 8.6 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 OAJ01646.1 - 0.0032 15.8 12.7 0.0046 15.3 12.7 1.1 1 0 0 1 1 1 1 Nop14-like family K_channel_TID PF07941.11 OAJ01646.1 - 0.027 14.9 1.1 0.027 14.9 1.1 4.0 3 1 1 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain CDC45 PF02724.14 OAJ01646.1 - 0.19 10.0 12.2 0.3 9.3 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ01646.1 - 0.2 11.7 16.1 0.52 10.4 16.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein SpoIIIAH PF12685.7 OAJ01646.1 - 3.3 7.5 11.2 2.5 7.9 7.2 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein SAPS PF04499.15 OAJ01646.1 - 7.2 5.3 5.7 12 4.5 4.2 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-RING_UBOX PF13445.6 OAJ01675.1 - 3.2e-06 27.1 1.2 7.8e-06 25.8 1.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ01675.1 - 5.1e-06 26.3 0.4 5.1e-06 26.3 0.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ01675.1 - 4.4e-05 23.3 6.5 0.00017 21.4 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ01675.1 - 6.8e-05 22.6 1.8 6.8e-05 22.6 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ01675.1 - 0.00053 19.9 2.7 0.0037 17.2 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAJ01675.1 - 0.0016 18.3 2.3 0.0035 17.2 1.4 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAJ01675.1 - 0.003 17.7 2.9 0.003 17.7 2.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ01675.1 - 0.0036 17.6 8.2 0.004 17.5 2.7 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OAJ01675.1 - 0.0082 16.0 6.7 0.015 15.1 1.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Rhodanese PF00581.20 OAJ01676.1 - 1.5e-05 25.4 0.0 2.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Ribonuclease PF00545.20 OAJ01721.1 - 2.4e-05 25.0 0.6 4.1e-05 24.2 0.6 1.3 1 0 0 1 1 1 1 ribonuclease FHA PF00498.26 OAJ01721.1 - 0.073 13.4 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 FHA domain NDC10_II PF16787.5 OAJ01742.1 - 6.6e-30 104.3 0.0 1.5e-29 103.1 0.0 1.5 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 FLILHELTA PF10306.9 OAJ01767.1 - 1.7e-14 53.9 0.0 3.8e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 OAJ01767.1 - 0.0054 17.3 0.3 0.01 16.4 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Chorein_N PF12624.7 OAJ01768.1 - 6.4e-11 42.4 0.0 3.5e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Helicase_C_2 PF13307.6 OAJ01804.1 - 1.7e-21 77.1 0.0 2.1e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Cutinase PF01083.22 OAJ01847.1 - 3e-19 69.6 0.0 3.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ01847.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 OAJ01847.1 - 0.032 14.8 0.1 0.035 14.7 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ01847.1 - 0.04 13.5 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 OAJ01847.1 - 0.074 13.2 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 OAJ01847.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 OAJ01847.1 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Myb_DNA-bind_4 PF13837.6 OAJ01917.1 - 0.017 15.5 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain T2SSF PF00482.23 OAJ01919.1 - 0.024 14.6 1.5 0.04 13.9 0.2 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Histone_HNS PF00816.21 OAJ01919.1 - 0.06 14.2 0.4 0.06 14.2 0.4 2.2 3 0 0 3 3 3 0 H-NS histone family CHDCT2 PF08074.11 OAJ01919.1 - 0.086 13.0 3.2 0.11 12.7 3.2 1.0 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain YlbD_coat PF14071.6 OAJ01919.1 - 0.18 12.0 1.6 0.27 11.5 1.0 1.5 1 1 1 2 2 2 0 Putative coat protein FUSC PF04632.12 OAJ01919.1 - 0.48 8.9 3.9 0.63 8.5 3.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2721 PF11026.8 OAJ01919.1 - 5.6 6.9 4.6 8.9 6.2 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) DDE_Tnp_4 PF13359.6 OAJ01920.1 - 1.1e-19 70.7 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ01920.1 - 0.00013 21.7 0.2 0.0036 17.0 0.0 2.4 1 1 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 OAJ01920.1 - 3.3 7.9 5.4 0.34 11.2 0.3 1.9 2 0 0 2 2 2 0 Transposase DDE domain RNase_H PF00075.24 OAJ01943.1 - 2.2e-08 34.4 0.0 3.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNase H AAA PF00004.29 OAJ01944.1 - 7.1e-18 65.3 0.0 4e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAJ01944.1 - 1.1e-06 28.8 0.5 9.7e-06 25.7 0.2 2.4 2 1 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.6 OAJ01944.1 - 0.014 15.8 2.7 0.25 11.7 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 OAJ01944.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ01944.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 OAJ01944.1 - 0.18 10.8 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region KASH_CCD PF14662.6 OAJ01970.1 - 0.00066 19.6 13.4 0.00066 19.6 13.4 1.8 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spore_III_AF PF09581.10 OAJ01970.1 - 0.1 12.6 11.4 0.2 11.6 0.6 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) KLRAQ PF10205.9 OAJ01970.1 - 1.6 9.0 11.5 3.1 8.1 8.8 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein HNOBA PF07701.14 OAJ01970.1 - 2.3 7.6 6.1 11 5.4 5.5 2.1 2 1 0 2 2 2 0 Heme NO binding associated PH_4 PF15404.6 OAJ01970.1 - 4.8 6.9 6.5 0.91 9.3 1.3 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain SPATA24 PF15175.6 OAJ01971.1 - 0.0018 18.2 0.9 0.0026 17.7 0.9 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Glyco_hydro_9 PF00759.19 OAJ01997.1 - 4.6 6.6 11.4 7.2 5.9 11.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Cation_ATPase_C PF00689.21 OAJ02045.1 - 1.2e-48 165.2 4.1 1.9e-47 161.4 1.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAJ02045.1 - 1.8e-48 164.5 4.7 1.9e-48 164.4 1.6 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ02045.1 - 3.3e-25 89.6 3.0 9.5e-25 88.1 3.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ02045.1 - 9.8e-20 70.0 0.0 2.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ02045.1 - 3.5e-17 62.3 0.0 6.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 OAJ02045.1 - 9.3e-07 29.4 0.0 2.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ02045.1 - 2.2e-06 27.6 0.7 4.2e-05 23.4 0.7 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TraL PF07178.11 OAJ02045.1 - 0.17 12.4 0.9 3.1 8.3 0.1 2.9 2 0 0 2 2 2 0 TraL protein SH3_9 PF14604.6 OAJ02077.1 - 2.6e-08 33.6 0.0 5.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ02077.1 - 2.1e-06 27.2 0.0 4.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain TMEM51 PF15345.6 OAJ02077.1 - 0.00022 21.1 0.3 0.00052 19.9 0.3 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 Mucin15 PF15672.5 OAJ02077.1 - 0.0063 16.0 1.1 0.0063 16.0 1.1 2.2 2 0 0 2 2 2 1 Cell-membrane associated Mucin15 APG12 PF04110.13 OAJ02103.1 - 6.9e-32 109.7 0.0 8.8e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OAJ02103.1 - 0.0049 17.0 0.0 0.0057 16.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ufm1 PF03671.14 OAJ02103.1 - 0.099 12.7 0.0 0.88 9.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fold modifier 1 protein FliP PF00813.20 OAJ02103.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 FliP family Ran_BP1 PF00638.18 OAJ02104.1 - 5.2e-51 172.0 2.0 8.8e-51 171.3 2.0 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OAJ02104.1 - 5.5e-06 26.3 1.0 3.1e-05 23.9 1.0 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 OAJ02104.1 - 0.00089 19.0 0.1 0.0011 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) VID27_PH PF17747.1 OAJ02104.1 - 0.0085 16.4 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain DUF4358 PF14270.6 OAJ02104.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) ASFV_J13L PF05568.11 OAJ02104.1 - 1.1 9.0 5.1 1.7 8.4 5.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein BTB_2 PF02214.22 OAJ02129.1 - 0.12 12.7 0.0 1.8 9.0 0.0 2.5 2 1 0 2 2 2 0 BTB/POZ domain CENP-B_dimeris PF09026.10 OAJ02129.1 - 0.21 12.0 7.8 4 7.9 1.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Na_Ca_ex PF01699.24 OAJ02130.1 - 5.3e-25 88.1 17.1 2.3e-18 66.6 9.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein OAD_gamma PF04277.13 OAJ02130.1 - 0.57 10.8 0.0 0.57 10.8 0.0 3.2 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain PIF1 PF05970.14 OAJ02155.1 - 7e-24 84.7 0.0 2.4e-23 82.9 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ02155.1 - 3.4e-05 23.7 0.0 5.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ02155.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dimer_Tnp_hAT PF05699.14 OAJ02156.1 - 4.8e-12 45.5 0.0 7.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FHA PF00498.26 OAJ02186.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 FHA domain Tim17 PF02466.19 OAJ02220.1 - 3.3e-35 120.8 4.6 4.3e-35 120.4 4.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ldr_toxin PF13940.6 OAJ02220.1 - 0.085 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system RRM_1 PF00076.22 OAJ02221.1 - 6.9e-18 64.2 0.0 1.2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ02221.1 - 1.2e-07 31.7 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ02221.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAJ02221.1 - 0.039 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mpv17_PMP22 PF04117.12 OAJ02222.1 - 1.6e-05 25.0 0.7 1.6e-05 25.0 0.7 2.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 OAJ02222.1 - 0.00076 19.8 1.1 0.11 12.9 0.2 3.1 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain RT_RNaseH PF17917.1 OAJ02250.1 - 1.3e-12 47.9 0.0 2.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ02250.1 - 2e-06 27.8 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ02250.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ02251.1 - 5.9e-23 81.5 0.0 9.1e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ02251.1 - 2.1e-13 50.1 0.0 4.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ02251.1 - 3e-06 27.8 0.1 1.2e-05 25.8 0.0 2.1 1 1 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 OAJ02251.1 - 0.00012 22.1 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OAJ02251.1 - 0.0012 19.4 0.0 0.0039 17.7 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 OAJ02251.1 - 0.12 12.6 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Dynamin_M PF01031.20 OAJ02288.1 - 5.7e-110 367.0 0.0 1.4e-109 365.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAJ02288.1 - 2.1e-56 190.6 0.0 3.6e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OAJ02288.1 - 8e-29 99.6 0.2 5.7e-28 96.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAJ02288.1 - 0.00037 20.5 0.1 0.0018 18.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ02288.1 - 0.048 14.0 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain TipAS PF07739.13 OAJ02288.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Spt20 PF12090.8 OAJ02288.1 - 6.7 6.2 12.1 0.23 11.0 3.2 2.3 2 0 0 2 2 2 0 Spt20 family Retrotrans_gag PF03732.17 OAJ02318.1 - 0.0084 16.4 0.6 0.0084 16.4 0.6 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 OAJ02319.1 - 1.8e-05 25.3 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ02319.1 - 0.003 18.1 0.0 0.009 16.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ02319.1 - 0.033 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.19 OAJ02319.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 dUTPase 2OG-FeII_Oxy_3 PF13640.6 OAJ02343.1 - 3e-08 34.5 0.1 7.4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OAJ02343.1 - 0.08 13.6 0.0 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PIF1 PF05970.14 OAJ02372.1 - 6.3e-19 68.4 0.0 7e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ02372.1 - 2.6e-06 27.3 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ02372.1 - 8.1e-05 23.0 0.0 0.00016 22.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAJ02372.1 - 0.0071 16.4 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OAJ02372.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OAJ02372.1 - 0.019 13.9 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 OAJ02372.1 - 0.045 13.7 0.2 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 OAJ02372.1 - 0.065 13.1 0.0 0.082 12.8 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OAJ02372.1 - 0.088 12.8 0.1 0.66 10.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Band_7 PF01145.25 OAJ02393.1 - 1.1e-23 84.2 6.4 1.1e-23 84.1 4.6 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAJ02393.1 - 0.0019 17.3 5.3 0.0036 16.4 5.3 1.4 1 1 0 1 1 1 1 SigmaW regulon antibacterial SRF-TF PF00319.18 OAJ02393.1 - 0.059 12.9 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Vma12 PF11712.8 OAJ02394.1 - 1.8e-29 102.6 0.1 3.4e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIIC_sub6 PF10419.9 OAJ02394.1 - 1.2e-11 44.4 0.0 2.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain PA_decarbox PF05870.11 OAJ02394.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) ALAD PF00490.21 OAJ02396.1 - 4e-119 397.5 0.0 4.6e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MPC PF03650.13 OAJ02397.1 - 7.9e-36 122.6 0.1 1.1e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Pex19 PF04614.12 OAJ02398.1 - 6.1e-56 189.9 0.7 6.1e-56 189.9 0.7 1.9 1 1 1 2 2 2 1 Pex19 protein family GCIP PF13324.6 OAJ02398.1 - 0.024 14.3 3.8 2 8.0 2.0 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF1018 PF06252.12 OAJ02398.1 - 0.038 15.0 0.0 35 5.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) HBS1_N PF08938.10 OAJ02398.1 - 3 8.2 7.4 0.52 10.6 1.8 2.5 3 0 0 3 3 3 0 HBS1 N-terminus CCDC53 PF10152.9 OAJ02398.1 - 8.8 6.7 9.8 0.44 11.0 3.4 2.0 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex RVT_1 PF00078.27 OAJ02426.1 - 8.6e-25 87.5 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ02426.1 - 1.6e-13 50.5 0.0 3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ02426.1 - 6.1e-10 39.3 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ02426.1 - 0.0009 19.2 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ02426.1 - 0.0012 19.1 0.0 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Trypan_PARP PF05887.11 OAJ02457.1 - 0.78 9.7 12.7 0.93 9.5 12.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 OAJ02457.1 - 4.8 5.3 12.2 5.3 5.1 12.2 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ02457.1 - 5 5.1 12.2 5.2 5.0 12.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 OAJ02457.1 - 7.2 7.1 18.7 9.9 6.6 12.9 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal bZIP_2 PF07716.15 OAJ02483.1 - 0.036 14.2 5.9 0.036 14.2 5.9 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF349 PF03993.12 OAJ02483.1 - 0.038 14.3 5.9 0.038 14.3 5.9 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) NYD-SP28_assoc PF14775.6 OAJ02483.1 - 0.42 10.7 2.9 0.94 9.6 2.9 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain CDH1_2_SANT_HL1 PF18375.1 OAJ02483.1 - 3.6 8.3 6.8 8.4 7.1 0.1 3.0 2 1 1 3 3 3 0 CDH1/2 SANT-Helical linker 1 Pkinase PF00069.25 OAJ02510.1 - 3.8e-42 144.5 0.0 5.6e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ02510.1 - 3.6e-26 92.0 0.0 4.9e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ02510.1 - 0.0075 15.6 0.0 0.12 11.6 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 OAJ02510.1 - 0.015 15.2 0.8 0.023 14.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ02510.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RTC4 PF14474.6 OAJ02510.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.8 1 1 0 1 1 1 0 RTC4-like domain GCR1_C PF12550.8 OAJ02536.1 - 2e-18 66.5 1.7 3.1e-18 65.9 1.7 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NPV_P10 PF05531.12 OAJ02536.1 - 0.046 14.2 0.8 0.11 12.9 0.8 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein NDC10_II PF16787.5 OAJ02537.1 - 2.1e-23 82.9 0.0 2.3e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Antifungal_pept PF11410.8 OAJ02567.1 - 0.00098 19.0 10.3 0.0043 16.9 1.4 2.5 2 0 0 2 2 2 2 Antifungal peptide ADAM_CR_2 PF17771.1 OAJ02567.1 - 0.0027 18.2 0.8 0.0027 18.2 0.8 2.2 2 0 0 2 2 2 1 ADAM cysteine-rich domain RNA_pol_Rpc4 PF05132.14 OAJ02567.1 - 0.043 14.2 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 AvrB_AvrC PF05394.11 OAJ02567.1 - 0.096 11.9 1.0 0.11 11.7 1.0 1.0 1 0 0 1 1 1 0 Avirulence protein EB PF01683.18 OAJ02567.1 - 0.31 11.4 6.7 0.47 10.8 6.7 1.4 1 0 0 1 1 1 0 EB module Aldo_ket_red PF00248.21 OAJ02568.1 - 9.3e-23 80.8 0.1 1.1e-21 77.3 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Ish1 PF10281.9 OAJ02568.1 - 0.041 14.2 0.0 3.3 8.1 0.0 3.2 2 1 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Slx4 PF09494.10 OAJ02568.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Slx4 endonuclease Aldo_ket_red PF00248.21 OAJ02569.1 - 1.7e-12 47.2 0.0 2.1e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.27 OAJ02596.1 - 2.7e-16 59.8 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP-alpha_N PF04086.13 OAJ02597.1 - 2.1 8.2 7.7 2.4 8.0 7.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 OAJ02597.1 - 6.1 5.3 9.5 6.2 5.2 9.5 1.1 1 0 0 1 1 1 0 Macoilin family SprA-related PF12118.8 OAJ02624.1 - 0.002 17.4 1.8 0.0023 17.1 1.8 1.0 1 0 0 1 1 1 1 SprA-related family PEHE PF15275.6 OAJ02624.1 - 0.039 14.6 2.5 0.045 14.4 2.5 1.1 1 0 0 1 1 1 0 PEHE domain GW PF13457.6 OAJ02626.1 - 0.031 14.9 0.2 0.044 14.4 0.2 1.4 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain Histone PF00125.24 OAJ02656.1 - 2.3e-43 147.7 0.7 2.6e-43 147.5 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ02656.1 - 1.4e-05 25.4 0.1 2.6e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 OAJ02656.1 - 0.00072 19.7 1.0 0.00089 19.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ02656.1 - 0.01 16.1 0.4 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1325 PF07039.11 OAJ02657.1 - 3e-09 37.0 0.0 3.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain PGM_PMM_I PF02878.16 OAJ02657.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RT_RNaseH_2 PF17919.1 OAJ02688.1 - 4.4e-20 71.6 0.0 9.3e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ02688.1 - 1.3e-19 70.5 0.0 3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ02688.1 - 1.9e-15 57.0 0.2 3.5e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3435 PF11917.8 OAJ02710.1 - 0.00032 19.7 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) RRN3 PF05327.11 OAJ02711.1 - 0.044 12.3 6.0 0.055 12.0 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ02711.1 - 3.7 5.5 12.6 5.1 5.1 12.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 OAJ02772.1 - 4.2e-71 239.4 0.0 6.1e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ02772.1 - 3.4e-39 134.7 0.0 5.6e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ02772.1 - 2.5e-05 23.8 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAJ02772.1 - 5e-05 22.9 0.4 0.0001 21.9 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OAJ02772.1 - 0.0003 20.2 0.1 0.0033 16.8 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OAJ02772.1 - 0.0034 16.2 0.0 0.0069 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAJ02772.1 - 0.0042 16.7 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ02772.1 - 0.0077 16.2 0.2 0.058 13.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family V-SNARE_C PF12352.8 OAJ02836.1 - 6e-17 61.7 3.9 1.5e-16 60.4 3.9 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAJ02836.1 - 0.00079 19.3 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 Sec20 Caudo_TAP PF02413.17 OAJ02836.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK BCDHK_Adom3 PF10436.9 OAJ02837.1 - 1.4e-39 135.5 0.0 2.3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ02837.1 - 2.2e-09 37.8 0.0 1.2e-05 25.8 0.0 3.1 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ02837.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Vac14_Fig4_bd PF11916.8 OAJ02865.1 - 6.3e-75 250.7 6.4 6.3e-75 250.7 6.4 2.3 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAJ02865.1 - 1.9e-45 153.4 0.0 1.9e-40 137.3 0.0 4.1 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAJ02865.1 - 4.9e-15 54.4 1.4 0.00074 19.6 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 OAJ02865.1 - 6.6e-08 32.8 0.8 0.0016 18.5 0.5 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAJ02865.1 - 2.5e-06 27.9 6.6 0.073 13.6 0.0 7.0 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 OAJ02865.1 - 2.9e-05 24.4 11.5 1.7 9.1 0.2 6.2 5 1 1 6 6 5 2 HEAT repeats ParcG PF10274.9 OAJ02865.1 - 0.00033 20.8 0.5 0.097 12.8 0.1 3.1 4 0 0 4 4 4 1 Parkin co-regulated protein CLASP_N PF12348.8 OAJ02865.1 - 0.0011 18.6 0.2 5.3 6.5 0.0 4.1 3 1 1 4 4 4 1 CLASP N terminal DUF3385 PF11865.8 OAJ02865.1 - 0.025 14.5 0.2 1.5 8.7 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Dopey_N PF04118.14 OAJ02865.1 - 0.031 13.4 0.1 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Dopey, N-terminal Tti2 PF10521.9 OAJ02865.1 - 0.04 13.5 1.4 18 4.7 0.0 3.9 4 1 1 5 5 5 0 Tti2 family Arm PF00514.23 OAJ02865.1 - 1.7 8.8 6.1 14 5.9 0.0 5.4 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Gelsolin PF00626.22 OAJ02868.1 - 3.2e-38 129.5 0.0 8.1e-15 54.5 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Questin_oxidase PF14027.6 OAJ02869.1 - 1.4e-80 271.4 1.6 1.7e-80 271.1 1.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like Glyco_hydro_47 PF01532.20 OAJ02898.1 - 5e-144 480.6 0.0 6.2e-144 480.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 OAJ02933.1 - 1.9e-31 107.6 14.7 4.5e-06 27.3 0.5 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 OAJ02933.1 - 5.4e-11 42.2 0.2 1.6e-10 40.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 OAJ02933.1 - 3.7e-05 23.2 0.3 8.7e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 OAJ02933.1 - 0.00018 21.3 0.1 0.00041 20.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 OAJ02933.1 - 0.062 13.8 0.9 52 4.5 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain TruD PF01142.18 OAJ02956.1 - 2e-48 165.3 0.0 1.3e-38 133.0 0.0 5.6 5 1 0 5 5 5 4 tRNA pseudouridine synthase D (TruD) Peptidase_M23 PF01551.22 OAJ02986.1 - 0.00031 20.9 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 EamA PF00892.20 OAJ03016.1 - 2.4 8.3 19.2 0.13 12.5 11.9 2.1 2 0 0 2 2 2 0 EamA-like transporter family AMP-binding PF00501.28 OAJ03017.1 - 1.3e-71 241.4 0.0 1.7e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ03017.1 - 3.3e-25 88.8 2.3 6.1e-25 88.0 0.1 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 OAJ03017.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ribosomal_L32p PF01783.23 OAJ03046.1 - 0.033 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L32p protein family UCH_1 PF13423.6 OAJ03049.1 - 4.6e-79 266.3 0.0 5.7e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAJ03049.1 - 5.6e-16 59.5 0.0 9.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease PH PF00169.29 OAJ03074.1 - 1.5e-05 25.4 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Syntaxin-6_N PF09177.11 OAJ03074.1 - 0.27 11.8 3.1 2.7 8.6 0.6 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CAF1A PF12253.8 OAJ03074.1 - 2.4 8.4 10.4 5.1 7.3 9.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A CH PF00307.31 OAJ03111.1 - 7e-78 257.9 0.0 1.2e-19 70.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OAJ03111.1 - 1.3e-05 24.9 0.0 0.66 9.9 0.0 3.8 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 OAJ03111.1 - 2.9e-05 24.4 0.3 2.9e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 OAJ03111.1 - 0.11 12.6 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein EF-hand_6 PF13405.6 OAJ03111.1 - 0.61 10.2 3.1 15 5.9 0.1 3.9 4 0 0 4 4 4 0 EF-hand domain Band_7 PF01145.25 OAJ03112.1 - 2e-09 37.7 2.7 3e-09 37.1 2.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF5365 PF17326.2 OAJ03112.1 - 0.16 12.4 0.5 0.23 11.9 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5365) Peptidase_S8 PF00082.22 OAJ03114.1 - 1.5e-39 136.1 0.0 6e-39 134.1 0.0 2.1 1 1 0 1 1 1 1 Subtilase family RVT_1 PF00078.27 OAJ03150.1 - 8.4e-18 64.7 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAJ03151.1 - 0.092 12.3 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TPPII_N PF12583.8 OAJ03189.1 - 1.9 9.1 5.4 2 9.0 5.4 1.0 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal UEV PF05743.13 OAJ03190.1 - 3.8e-37 126.8 0.1 5.9e-37 126.2 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OAJ03190.1 - 1e-23 83.0 0.4 2.1e-23 82.0 0.4 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 OAJ03190.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TMEM208_SND2 PF05620.11 OAJ03191.1 - 9.3e-38 129.6 10.8 2.3e-37 128.4 10.8 1.6 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Ribosomal_S28e PF01200.18 OAJ03192.1 - 2.2e-31 107.6 0.6 2.5e-31 107.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Pec_lyase_C PF00544.19 OAJ03192.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Pectate lyase ATP-synt_ab PF00006.25 OAJ03221.1 - 6.3e-106 352.8 0.0 8.9e-106 352.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OAJ03221.1 - 4.3e-43 146.0 0.0 7.6e-43 145.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OAJ03221.1 - 3.5e-14 53.1 3.1 1e-13 51.6 3.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATG16 PF08614.11 OAJ03222.1 - 2.7e-46 158.3 23.9 3.3e-46 158.0 23.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OAJ03222.1 - 0.0031 16.6 7.7 0.0031 16.6 7.7 1.6 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 OAJ03222.1 - 0.17 13.0 12.1 2.7 9.2 3.3 3.1 2 1 2 4 4 4 0 Protein SOGA SHE3 PF17078.5 OAJ03222.1 - 0.28 10.9 12.7 0.1 12.3 10.3 1.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 RAP1 PF07218.11 OAJ03222.1 - 0.44 8.8 2.5 0.4 8.9 1.5 1.4 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V_ATPase_I PF01496.19 OAJ03222.1 - 0.45 8.4 4.1 0.14 10.1 1.5 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 OAJ03222.1 - 0.47 10.9 6.1 6.2 7.3 0.6 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FlgN PF05130.12 OAJ03222.1 - 0.75 10.3 16.7 0.073 13.6 5.9 2.5 1 1 1 2 2 2 0 FlgN protein Fib_alpha PF08702.10 OAJ03222.1 - 1.1 9.4 14.0 0.097 12.9 6.6 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 OAJ03222.1 - 1.5 9.4 23.3 1.3 9.5 10.2 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 OAJ03222.1 - 1.6 9.1 4.3 18 5.6 1.7 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OAJ03222.1 - 2.1 9.0 16.2 2.3 8.9 2.9 3.0 2 1 1 3 3 3 0 Initiation control protein YabA FAM76 PF16046.5 OAJ03222.1 - 2.6 7.3 8.7 20 4.4 8.7 2.0 1 1 0 1 1 1 0 FAM76 protein OmpH PF03938.14 OAJ03222.1 - 7.5 6.9 16.1 4 7.8 11.6 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Collagen_mid PF15984.5 OAJ03255.1 - 5e-05 23.2 8.4 0.00098 18.9 0.7 2.2 1 1 1 2 2 2 2 Bacterial collagen, middle region Apolipoprotein PF01442.18 OAJ03255.1 - 0.0019 18.1 0.7 0.016 15.1 0.3 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 OAJ03255.1 - 0.0087 16.3 4.2 0.065 13.5 0.7 3.1 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) I_LWEQ PF01608.17 OAJ03255.1 - 0.021 15.1 1.7 0.29 11.4 0.0 2.6 1 1 1 2 2 2 0 I/LWEQ domain ApoLp-III PF07464.11 OAJ03255.1 - 0.024 14.7 0.6 1.4 9.0 0.3 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OAJ03255.1 - 0.041 13.9 1.5 1.1 9.3 0.9 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 OAJ03255.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CAF1-p150_C2 PF15539.6 OAJ03257.1 - 0.18 11.3 0.5 0.51 9.7 0.5 1.7 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Dicty_REP PF05086.12 OAJ03294.1 - 9.3 4.1 4.8 12 3.7 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAD_binding_4 PF01565.23 OAJ03295.1 - 1.9e-26 92.5 1.7 3.4e-26 91.7 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ03295.1 - 3.1e-06 27.2 0.1 6.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like REV PF00424.18 OAJ03295.1 - 0.13 12.3 0.6 0.31 11.1 0.6 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DHHC PF01529.20 OAJ03337.1 - 6.1e-34 117.0 4.1 1.5e-33 115.8 4.1 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Arc_PepC_II PF06847.11 OAJ03337.1 - 6.5 7.3 6.6 0.48 11.0 1.4 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II tRNA_int_end_N2 PF12928.7 OAJ03370.1 - 5.6e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OAJ03370.1 - 0.00019 21.0 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain TFIIF_alpha PF05793.12 OAJ03371.1 - 0.23 10.0 11.0 0.34 9.5 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PIEZO PF15917.5 OAJ03371.1 - 0.85 9.1 4.6 1.4 8.3 4.6 1.3 1 0 0 1 1 1 0 Piezo NARP1 PF12569.8 OAJ03371.1 - 1.1 8.1 7.0 1.6 7.5 7.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nop14 PF04147.12 OAJ03371.1 - 1.6 6.8 13.8 2.1 6.4 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-bind_3 PF12776.7 OAJ03405.1 - 4.3e-06 27.6 0.2 8.5e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 OAJ03405.1 - 0.0072 16.3 1.5 0.0089 16.0 1.5 1.1 1 0 0 1 1 1 1 Myc amino-terminal region DUF4611 PF15387.6 OAJ03405.1 - 0.04 14.1 5.9 0.04 14.1 5.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF913 PF06025.12 OAJ03405.1 - 0.15 11.0 0.4 0.2 10.6 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 OAJ03405.1 - 0.42 10.3 2.0 0.62 9.7 2.0 1.3 1 0 0 1 1 1 0 FAM176 family Trypan_PARP PF05887.11 OAJ03405.1 - 0.57 10.2 4.0 0.85 9.6 4.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CENP-B_dimeris PF09026.10 OAJ03405.1 - 1.6 9.2 10.3 3 8.3 10.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ03405.1 - 2.5 7.3 8.0 3.3 7.0 8.0 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ03405.1 - 2.8 6.1 5.5 2.8 6.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ03405.1 - 9.5 4.2 10.8 11 3.9 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi RVT_2 PF07727.14 OAJ03408.1 - 5.9e-72 242.2 0.0 8.5e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 OAJ03408.1 - 0.041 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 rve PF00665.26 OAJ03410.1 - 0.00015 21.9 0.0 0.0004 20.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ03410.1 - 0.00046 20.0 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DPBB_1 PF03330.18 OAJ03443.1 - 4e-06 27.0 0.2 6.2e-05 23.2 0.2 2.5 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 OAJ03443.1 - 0.0001 22.1 0.5 0.36 10.7 0.2 2.5 2 0 0 2 2 2 2 Barwin family SR-25 PF10500.9 OAJ03479.1 - 0.59 9.7 10.0 1 8.9 10.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 OAJ03482.1 - 1.5e-05 24.8 0.7 1.2 9.6 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Pkinase PF00069.25 OAJ03482.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 OAJ03482.1 - 0.0017 18.5 0.0 0.017 15.1 0.0 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAJ03482.1 - 0.0059 17.1 3.1 0.02 15.4 0.2 3.5 4 0 0 4 4 4 1 HEAT-like repeat DUF1217 PF06748.12 OAJ03482.1 - 0.099 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) AA_permease_2 PF13520.6 OAJ03518.1 - 4.8e-09 35.6 13.6 1.3e-07 30.9 12.5 2.0 1 1 1 2 2 2 2 Amino acid permease RT_RNaseH_2 PF17919.1 OAJ03561.1 - 0.00016 21.7 0.0 0.00056 19.9 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ03561.1 - 0.0042 17.3 0.0 0.0086 16.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ03561.1 - 0.0087 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ03562.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease BRF1 PF07741.13 OAJ03562.1 - 0.21 12.0 0.6 0.73 10.2 0.6 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain zf-CCHC PF00098.23 OAJ03562.1 - 0.68 10.1 3.9 0.31 11.2 1.5 1.7 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 OAJ03605.1 - 2.7e-26 92.5 0.0 4.7e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ03605.1 - 5.2e-16 58.5 0.0 1.9e-13 50.3 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ03605.1 - 7.7e-14 51.5 0.0 1.9e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ03605.1 - 3e-11 43.5 0.0 8.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ03605.1 - 6e-06 26.5 0.0 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ03605.1 - 2.1e-05 25.1 0.1 7.1e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ03605.1 - 0.0045 17.5 0.0 0.017 15.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease dUTPase PF00692.19 OAJ03605.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 dUTPase RVP PF00077.20 OAJ03605.1 - 0.089 13.1 0.0 0.43 10.9 0.0 2.1 3 0 0 3 3 3 0 Retroviral aspartyl protease Senescence PF06911.12 OAJ03642.1 - 2.9e-32 112.5 1.4 4.5e-32 111.9 1.4 1.3 1 0 0 1 1 1 1 Senescence-associated protein Gar1 PF04410.14 OAJ03681.1 - 9.8e-28 96.9 0.5 2.1e-15 56.8 0.1 3.3 3 0 0 3 3 3 2 Gar1/Naf1 RNA binding region AF-4 PF05110.13 OAJ03681.1 - 0.00027 19.2 18.7 0.00027 19.2 18.7 4.2 3 1 1 4 4 4 2 AF-4 proto-oncoprotein FoP_duplication PF13865.6 OAJ03682.1 - 7.9e-06 26.3 2.2 1.4e-05 25.5 2.1 1.5 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ccdc124 PF06244.12 OAJ03761.1 - 3.5e-24 85.8 28.5 1.4e-22 80.6 28.5 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HTH_WhiA PF02650.14 OAJ03761.1 - 0.28 11.5 6.6 4.6 7.7 0.1 2.8 2 1 1 3 3 3 0 WhiA C-terminal HTH domain DUF3153 PF11353.8 OAJ03761.1 - 0.46 10.0 1.7 0.57 9.7 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) Toprim_2 PF13155.6 OAJ03761.1 - 3.9 8.0 7.3 1.3 9.5 0.7 3.2 3 1 0 3 3 3 0 Toprim-like Cript PF10235.9 OAJ03762.1 - 3.8e-26 91.5 6.4 3.8e-26 91.5 6.4 2.0 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 OAJ03762.1 - 0.015 15.6 7.2 0.015 15.6 7.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 OAJ03762.1 - 0.3 11.5 9.6 0.16 12.4 4.8 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal zinc_ribbon_2 PF13240.6 OAJ03762.1 - 0.3 10.9 11.3 0.23 11.2 2.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Phage_integrase PF00589.22 OAJ03799.1 - 0.007 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAJ03799.1 - 0.18 12.1 0.3 0.99 9.8 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain SR-25 PF10500.9 OAJ03799.1 - 5.3 6.6 11.6 8.6 5.9 11.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 OAJ03834.1 - 1.9e-24 86.4 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ03834.1 - 3.7e-22 78.3 0.0 1.1e-13 51.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ03834.1 - 3e-17 62.8 0.0 1.9e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ03834.1 - 7.2e-16 58.0 0.1 1.4e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ03834.1 - 7.2e-11 42.3 0.0 2.2e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ03834.1 - 7.9e-05 23.2 0.0 0.00033 21.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ03834.1 - 0.0051 17.4 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ03834.1 - 0.013 15.8 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 OAJ03834.1 - 0.02 15.1 0.0 0.065 13.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH_2 PF17919.1 OAJ03872.1 - 5.9e-20 71.2 0.0 6.3e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ03872.1 - 3.6e-14 52.6 0.1 6.8e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ03872.1 - 5e-14 52.4 0.0 8.1e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ03872.1 - 3.2e-11 43.4 0.0 8.5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ03872.1 - 4.3e-06 26.4 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 OAJ03872.1 - 0.012 15.8 0.1 0.029 14.6 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 OAJ03873.1 - 0.00027 21.5 0.0 0.001 19.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ03873.1 - 0.0066 17.0 0.1 0.045 14.3 0.1 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Transposase_21 PF02992.14 OAJ03918.1 - 6.1e-09 35.4 0.0 1.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Leucyl-specific PF14795.6 OAJ03918.1 - 0.048 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Arylsulfotran_2 PF14269.6 OAJ03953.1 - 2.1e-36 125.8 0.0 5.9e-36 124.4 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAJ03953.1 - 6.1e-09 35.2 2.6 1.4e-08 34.0 2.7 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LRR_4 PF12799.7 OAJ03954.1 - 1.6e-24 85.6 13.9 3.3e-07 30.5 0.4 5.8 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ03954.1 - 1.4e-19 69.6 15.9 8e-06 25.5 0.1 5.3 2 1 4 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 OAJ03954.1 - 1.7e-18 66.8 0.8 1.6e-07 31.0 0.0 3.8 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 OAJ03954.1 - 3.6e-09 35.9 7.4 0.23 11.6 0.0 7.0 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 OAJ03954.1 - 5.2e-07 29.3 12.4 25 5.9 0.0 7.6 7 1 0 7 7 7 1 Leucine Rich Repeat Arm_3 PF16186.5 OAJ03954.1 - 0.093 12.3 0.1 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Atypical Arm repeat RVT_1 PF00078.27 OAJ04024.1 - 3.2e-18 66.1 0.0 6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 OAJ04054.1 - 0.96 9.8 3.7 0.61 10.4 0.4 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein GRP PF07172.11 OAJ04054.1 - 1.6 9.4 29.2 2.8 8.7 29.2 1.3 1 0 0 1 1 1 0 Glycine rich protein family TFIIF_alpha PF05793.12 OAJ04091.1 - 3.4 6.1 38.5 11 4.4 38.5 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 OAJ04091.1 - 4 6.8 34.5 14 5.0 34.5 1.9 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ04091.1 - 7.4 4.7 25.2 21 3.3 25.2 1.7 1 0 0 1 1 1 0 CDC45-like protein Transposase_21 PF02992.14 OAJ04093.1 - 4.5e-15 55.5 0.0 8e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Spc29 PF17082.5 OAJ04093.1 - 7.4 6.3 11.6 0.8 9.5 4.4 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 Abhydrolase_8 PF06259.12 OAJ04134.1 - 0.014 15.1 0.0 2.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase Peptidase_M17_N PF02789.17 OAJ04134.1 - 0.067 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain OpgC_C PF10129.9 OAJ04134.1 - 0.25 10.2 0.5 0.31 9.9 0.5 1.1 1 0 0 1 1 1 0 OpgC protein Ribosomal_L7Ae PF01248.26 OAJ04170.1 - 1.8e-27 94.9 1.7 2.3e-27 94.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1353 PF07087.11 OAJ04170.1 - 0.039 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Ribosomal_S17_N PF16205.5 OAJ04171.1 - 8.6e-31 106.1 1.1 9.9e-31 105.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAJ04171.1 - 6.8e-27 93.4 0.3 6.8e-27 93.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 RVT_1 PF00078.27 OAJ04204.1 - 6.2e-20 71.7 0.0 1e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ04204.1 - 4.1e-16 58.8 0.0 8.1e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ04204.1 - 4.9e-13 49.0 0.0 9.3e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ04204.1 - 0.0029 18.2 0.0 0.0075 16.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ04204.1 - 0.0075 16.5 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ04204.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ04205.1 - 3.6e-11 43.3 0.0 5.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ04205.1 - 5.8e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage-tail_3 PF13550.6 OAJ04205.1 - 0.039 13.8 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Putative phage tail protein MULE PF10551.9 OAJ04207.1 - 2.2e-11 44.0 0.0 6.6e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ04207.1 - 1.4e-07 31.1 0.2 2.6e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Collagen PF01391.18 OAJ04245.1 - 4.6e-15 55.1 60.5 2.5e-09 36.7 28.4 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) YrhK PF14145.6 OAJ04245.1 - 0.0099 15.7 0.2 13 5.8 0.0 3.3 3 0 0 3 3 3 2 YrhK-like protein FSA_C PF10479.9 OAJ04245.1 - 3.8 5.5 8.5 5.8 4.9 8.5 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NUDE_C PF04880.13 OAJ04245.1 - 8.9 6.7 8.4 29 5.1 8.4 1.8 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TPR_12 PF13424.6 OAJ04281.1 - 5.7e-29 100.2 57.4 0.00051 20.3 4.7 14.1 7 5 6 13 13 13 9 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ04281.1 - 3.2e-28 96.7 50.6 0.011 15.6 0.0 15.6 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ04281.1 - 2e-10 39.9 28.0 2.8 8.3 0.2 12.9 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ04281.1 - 2.5e-05 23.9 9.6 14 5.7 0.0 9.1 10 0 0 10 10 10 1 Tetratricopeptide repeat Phage_tail_U PF06141.11 OAJ04281.1 - 0.011 16.1 0.8 0.68 10.3 0.0 4.1 5 1 1 6 6 6 0 Phage minor tail protein U DUF4754 PF15946.5 OAJ04281.1 - 0.017 15.4 15.9 0.49 10.7 0.5 5.1 4 2 1 5 5 5 0 Domain of unknown function (DUF4754) SPG48 PF14764.6 OAJ04281.1 - 0.029 14.8 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking DUF3856 PF12968.7 OAJ04281.1 - 0.045 13.8 20.4 0.28 11.2 1.3 6.5 3 3 6 9 9 9 0 Domain of Unknown Function (DUF3856) M PF02370.16 OAJ04281.1 - 0.069 13.7 0.8 1.2 10.0 1.3 3.0 2 0 0 2 2 1 0 M protein repeat Zwint PF15556.6 OAJ04281.1 - 0.07 12.6 2.2 0.55 9.7 0.3 2.5 2 0 0 2 2 2 0 ZW10 interactor Prefoldin_2 PF01920.20 OAJ04281.1 - 0.25 11.3 6.4 28 4.7 0.2 5.4 5 0 0 5 5 5 0 Prefoldin subunit TPR_8 PF13181.6 OAJ04281.1 - 1 9.7 22.4 71 4.0 0.0 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat FA_hydroxylase PF04116.13 OAJ04323.1 - 9.4e-20 71.3 9.1 9.4e-20 71.3 9.1 2.4 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily RVT_1 PF00078.27 OAJ04325.1 - 5.3e-09 35.9 0.0 5.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3762 PF12591.8 OAJ04325.1 - 0.058 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) rve PF00665.26 OAJ04326.1 - 1.7e-15 57.2 0.0 3.6e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ04326.1 - 0.0033 17.2 0.0 0.0082 15.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ04326.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain PHBC_N PF12551.8 OAJ04368.1 - 0.00077 19.2 1.5 0.00099 18.8 1.5 1.2 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase N terminal Peroxidase_2 PF01328.17 OAJ04369.1 - 4.5e-43 148.0 0.0 6.9e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Orexin PF02072.15 OAJ04411.1 - 0.16 11.9 0.3 0.28 11.1 0.3 1.3 1 0 0 1 1 1 0 Prepro-orexin NDC10_II PF16787.5 OAJ04414.1 - 5.9e-34 117.6 0.0 8.3e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Molybdopterin_N PF18364.1 OAJ04414.1 - 0.14 12.2 0.7 23 5.1 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain Baculo_PEP_C PF04513.12 OAJ04414.1 - 0.52 10.3 3.8 0.22 11.5 1.1 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Inhibitor_I66 PF16850.5 OAJ04457.1 - 0.001 19.0 0.0 0.0068 16.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I66 SoxE PF06525.11 OAJ04457.1 - 0.11 12.0 0.2 1.9 7.9 0.0 2.2 1 1 1 2 2 2 0 Sulfocyanin (SoxE) domain Inhibitor_I66 PF16850.5 OAJ04458.1 - 0.00063 19.6 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I66 RVT_1 PF00078.27 OAJ04496.1 - 3.2e-31 108.6 0.0 4.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hist_deacetyl PF00850.19 OAJ04531.1 - 1.9e-67 227.9 2.4 2e-67 227.8 1.4 1.5 2 0 0 2 2 2 1 Histone deacetylase domain SUIM_assoc PF16619.5 OAJ04531.1 - 0.01 15.9 0.7 0.022 14.8 0.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Herpes_UL32 PF06070.11 OAJ04531.1 - 0.19 9.5 2.4 0.35 8.6 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF3915 PF13054.6 OAJ04531.1 - 7.4 6.6 6.7 7.5 6.6 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DDHD PF02862.17 OAJ04532.1 - 1.5 8.9 5.1 5.5 7.1 0.0 2.2 1 1 1 2 2 2 0 DDHD domain IF-2B PF01008.17 OAJ04562.1 - 7.1e-61 205.9 0.0 9.8e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family FTZ PF03867.14 OAJ04562.1 - 0.0099 15.4 1.6 0.018 14.6 1.6 1.3 1 0 0 1 1 1 1 Fushi tarazu (FTZ), N-terminal region Pex14_N PF04695.13 OAJ04562.1 - 3.9 8.1 8.5 1.5 9.5 1.2 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sugar_tr PF00083.24 OAJ04563.1 - 1.4e-85 287.9 20.4 1.6e-85 287.7 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ04563.1 - 6e-28 97.8 22.8 6e-28 97.8 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAJ04563.1 - 0.00028 19.4 0.5 0.00056 18.5 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MutS_V PF00488.21 OAJ04608.1 - 1.9e-16 60.6 0.5 2.7e-11 43.8 0.2 2.1 1 1 1 2 2 2 2 MutS domain V MutS_V PF00488.21 OAJ04609.1 - 0.0017 18.4 0.1 0.0031 17.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V Adeno_E4_34 PF04528.13 OAJ04609.1 - 0.15 11.9 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region DUF3416 PF11896.8 OAJ04610.1 - 0.0017 18.7 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Vip3A_N PF12495.8 OAJ04610.1 - 0.027 14.4 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal MutS_II PF05188.17 OAJ04611.1 - 1.6e-08 34.9 0.1 2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 MutS domain II DUF1542 PF07564.11 OAJ04652.1 - 0.59 10.3 3.4 2.8 8.1 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) ASF1_hist_chap PF04729.13 OAJ04697.1 - 4.1e-11 43.1 0.0 4.2e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone ICL PF00463.21 OAJ04698.1 - 3e-118 395.6 3.2 5e-65 220.0 0.0 3.7 1 1 2 3 3 3 3 Isocitrate lyase family Arg_repressor_C PF02863.18 OAJ04698.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain RVT_1 PF00078.27 OAJ04742.1 - 2.8e-24 85.9 0.0 4.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ04742.1 - 2.3e-14 53.2 0.0 4.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ04742.1 - 1.6e-11 44.4 0.0 3.5e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ04742.1 - 1.6e-09 38.0 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ04742.1 - 1.6e-06 28.0 0.1 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ04742.1 - 4.2e-06 27.3 0.1 1.3e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ04742.1 - 0.0008 19.9 0.0 0.002 18.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ04742.1 - 0.099 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 OAJ04742.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Exo_endo_phos_2 PF14529.6 OAJ04784.1 - 5e-12 45.7 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 OAJ04784.1 - 3.4e-09 36.5 0.0 4.8e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAJ04784.1 - 1.2e-05 24.9 0.9 3.8e-05 23.3 0.9 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRP7 PF12923.7 OAJ04784.1 - 0.12 12.6 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MTBP_C PF14920.6 OAJ04784.1 - 0.44 10.3 3.9 1.1 9.0 3.9 1.6 1 0 0 1 1 1 0 MDM2-binding Mating_C PF12737.7 OAJ04831.1 - 0.045 13.0 0.1 0.051 12.8 0.1 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 RT_RNaseH PF17917.1 OAJ04837.1 - 3.3e-12 46.6 0.0 5.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ04837.1 - 3.5e-06 27.0 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ProQ_C PF17516.2 OAJ04837.1 - 0.037 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 ProQ C-terminal domain Integrase_H2C2 PF17921.1 OAJ04838.1 - 6.2e-16 58.3 0.0 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ04838.1 - 3.7e-13 49.7 0.0 2.1e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ04838.1 - 5.1e-13 48.9 0.1 1.4e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ04838.1 - 0.09 13.1 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ05011.1 - 4.5e-20 72.1 0.1 9.7e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bcl-2_BAD PF10514.9 OAJ05011.1 - 0.03 14.8 0.0 0.047 14.2 0.0 1.2 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD rve PF00665.26 OAJ05012.1 - 3.4e-16 59.5 0.1 7.1e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ05012.1 - 1.8e-14 53.6 0.2 4.5e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ05012.1 - 0.0018 18.0 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PAS_3 PF08447.12 OAJ05012.1 - 0.19 12.1 1.0 0.89 9.9 0.8 2.3 2 0 0 2 2 2 0 PAS fold Exo_endo_phos PF03372.23 OAJ05016.1 - 0.014 15.0 3.0 0.086 12.3 3.0 2.1 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 OAJ05067.1 - 6.9e-37 125.1 0.0 2.7e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ05067.1 - 0.023 14.7 0.0 9.3 6.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DUF3344 PF11824.8 OAJ05067.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) ATP-grasp_2 PF08442.10 OAJ05067.1 - 0.027 14.0 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Glyco_hydro_30 PF02055.16 OAJ05068.1 - 5e-18 65.2 0.5 3.9e-17 62.3 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OAJ05068.1 - 7.9e-06 25.3 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 DUF5127 PF17168.4 OAJ05113.1 - 3.3e-48 164.4 1.5 4.6e-48 164.0 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 OAJ05113.1 - 7.8e-35 120.1 0.0 1.2e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF4964 PF16334.5 OAJ05113.1 - 3.4e-06 26.5 1.6 0.038 13.5 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ05113.1 - 0.00024 20.7 0.3 0.00052 19.6 0.1 1.5 2 0 0 2 2 2 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term RVT_1 PF00078.27 OAJ05115.1 - 5.2e-23 81.7 0.0 9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ05115.1 - 6.2e-23 80.7 0.0 8.5e-15 54.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ05115.1 - 1.6e-16 60.5 0.0 1.3e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ05115.1 - 5.2e-13 48.9 0.0 9.7e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ05115.1 - 9.7e-11 41.9 0.0 4.1e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ05115.1 - 0.00022 21.8 0.0 0.00075 20.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease dUTPase PF00692.19 OAJ05115.1 - 0.048 13.4 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 dUTPase gag-asp_proteas PF13975.6 OAJ05115.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Sec23_trunk PF04811.15 OAJ05202.1 - 1.4e-75 254.1 0.0 2e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAJ05202.1 - 4.3e-31 107.5 0.0 7.9e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAJ05202.1 - 6.5e-26 90.2 0.2 1.3e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAJ05202.1 - 1.8e-15 56.7 5.5 3.3e-15 55.8 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAJ05202.1 - 6e-13 48.5 0.0 1.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAJ05202.1 - 0.08 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RF-1 PF00472.20 OAJ05203.1 - 4.6e-18 65.2 0.4 6.7e-18 64.7 0.4 1.2 1 0 0 1 1 1 1 RF-1 domain RVT_1 PF00078.27 OAJ05252.1 - 1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSP1 PF04468.12 OAJ05299.1 - 2.5e-30 104.6 0.3 4.1e-30 103.9 0.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Serinc PF03348.15 OAJ05352.1 - 6.5e-59 200.0 0.0 8.5e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) SUR7 PF06687.12 OAJ05406.1 - 0.24 11.0 4.7 3.5 7.2 0.4 3.0 3 0 0 3 3 3 0 SUR7/PalI family MMS19_C PF12460.8 OAJ05407.1 - 8.7e-11 41.6 0.0 1.4e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 OAJ05407.1 - 0.018 15.3 2.5 0.17 12.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OAJ05407.1 - 0.08 13.3 2.2 1.5 9.3 0.4 2.3 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 OAJ05407.1 - 0.52 10.9 3.4 2.8 8.6 0.4 2.5 2 0 0 2 2 2 0 HEAT-like repeat DUF1302 PF06980.11 OAJ05410.1 - 1e-117 394.2 10.9 1.7e-117 393.5 10.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1302) DUF1329 PF07044.11 OAJ05411.1 - 2.1e-113 379.3 5.2 2.6e-113 379.0 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) LolA_like PF17131.4 OAJ05411.1 - 1.6e-06 28.0 1.1 5.6e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Outer membrane lipoprotein-sorting protein YL1 PF05764.13 OAJ05457.1 - 0.0011 19.1 15.5 0.0011 19.1 15.5 1.4 2 0 0 2 2 2 1 YL1 nuclear protein TSC22 PF01166.18 OAJ05457.1 - 0.023 15.0 0.4 0.074 13.4 0.4 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family CDC45 PF02724.14 OAJ05457.1 - 0.075 11.3 11.4 0.11 10.7 11.4 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ05457.1 - 0.14 11.6 12.5 0.23 10.8 12.5 1.4 1 0 0 1 1 1 0 SDA1 HET PF06985.11 OAJ05457.1 - 1.6 9.1 5.5 0.32 11.3 0.3 2.3 2 1 1 3 3 3 0 Heterokaryon incompatibility protein (HET) Asp_protease_2 PF13650.6 OAJ05501.1 - 3.7e-05 24.3 0.2 0.00013 22.6 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ05501.1 - 0.0012 19.4 0.0 0.0029 18.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tyrosinase PF00264.20 OAJ05502.1 - 0.016 15.5 0.7 0.021 15.1 0.7 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase Polysacc_synt_3 PF13440.6 OAJ05502.1 - 1.5 8.0 9.7 0.083 12.1 4.2 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_trans_2_3 PF13632.6 OAJ05551.1 - 3.4e-20 72.8 4.2 3.4e-20 72.8 4.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAJ05551.1 - 1.5e-18 67.5 0.0 2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ05551.1 - 1.1e-09 38.0 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ05551.1 - 2.6e-07 30.6 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ribosomal_L29e PF01779.17 OAJ05552.1 - 6.6e-09 35.9 1.0 1.1e-08 35.2 1.0 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Pkinase PF00069.25 OAJ05586.1 - 7.1e-63 212.4 0.0 6.3e-62 209.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ05586.1 - 1.9e-26 92.9 0.0 2.5e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ05586.1 - 0.00036 20.0 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ05586.1 - 0.0035 16.3 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ05586.1 - 0.09 12.7 3.6 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family NAM-associated PF14303.6 OAJ05586.1 - 5.5 7.7 7.3 3.1 8.5 4.5 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain TFIIA PF03153.13 OAJ05586.1 - 7.8 6.4 6.4 12 5.8 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cellulase PF00150.18 OAJ05640.1 - 5.9e-06 25.9 0.1 8.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chorein_N PF12624.7 OAJ05695.1 - 6.4e-34 116.5 0.0 1.4e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 OAJ05695.1 - 2.8e-28 99.3 0.1 4.2e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal adh_short PF00106.25 OAJ05695.1 - 0.00022 20.7 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ05695.1 - 0.0006 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ05695.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 KR domain VPS13 PF16908.5 OAJ05696.1 - 1.6e-21 77.2 1.8 2e-21 76.9 0.2 1.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal DUF4085 PF13315.6 OAJ05696.1 - 0.0064 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) MFS_1 PF07690.16 OAJ05697.1 - 2.7e-06 26.5 1.3 3.6e-06 26.2 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_integrase PF00589.22 OAJ05699.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Ecl1 PF12855.7 OAJ05699.1 - 8.1 7.6 21.1 14 6.8 21.1 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins RVT_3 PF13456.6 OAJ05700.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ05700.1 - 0.0061 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain RT_RNaseH_2 PF17919.1 OAJ05700.1 - 0.039 14.0 0.1 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ05756.1 - 5.8e-15 55.4 0.0 7.4e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SelP_N PF04592.14 OAJ05759.1 - 1.2 8.5 7.0 1.6 8.1 7.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LIP PF03583.14 OAJ05760.1 - 7e-33 114.2 0.0 8.5e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase RVT_1 PF00078.27 OAJ05814.1 - 2.9e-24 85.8 0.0 4.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ05814.1 - 4e-13 49.2 0.1 9.8e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 OAJ05814.1 - 6.9e-09 36.0 0.3 3.6e-08 33.7 0.1 2.4 2 1 0 2 2 2 1 RNase H Exo_endo_phos PF03372.23 OAJ05814.1 - 4.1e-05 23.2 0.7 0.00045 19.8 0.7 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC_export PF16962.5 OAJ05814.1 - 0.25 9.7 0.0 0.37 9.2 0.0 1.1 1 0 0 1 1 1 0 Putative ABC exporter FAS_I_H PF18314.1 OAJ05816.1 - 7.4e-69 231.4 0.6 9.9e-69 231.0 0.6 1.2 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAJ05816.1 - 1.4e-51 175.0 0.0 2.6e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ACPS PF01648.20 OAJ05817.1 - 0.00085 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 OAJ05817.1 - 0.024 14.1 0.2 0.042 13.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RT_RNaseH_2 PF17919.1 OAJ05867.1 - 1.3e-16 60.4 0.0 5.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ05867.1 - 8.8e-13 48.2 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ05867.1 - 9.6e-13 48.3 0.0 2.6e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ05867.1 - 2e-07 31.2 0.0 5.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ05867.1 - 0.00043 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 OAJ05867.1 - 0.0076 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Inhibitor_Mig-6 PF11555.8 OAJ05868.1 - 0.076 13.1 5.9 0.19 11.8 5.9 1.7 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 THOC7 PF05615.13 OAJ05930.1 - 3.1e-17 63.1 4.3 3.1e-17 63.1 4.3 2.5 1 1 1 2 2 2 1 Tho complex subunit 7 IFT20 PF14931.6 OAJ05930.1 - 0.018 15.2 4.4 0.034 14.3 0.4 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Phlebovirus_NSM PF07246.11 OAJ05930.1 - 0.038 13.4 1.7 0.041 13.3 0.3 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Occludin_ELL PF07303.13 OAJ05930.1 - 0.1 13.3 1.1 0.28 11.9 1.1 1.8 1 0 0 1 1 1 0 Occludin homology domain APG6_N PF17675.1 OAJ05930.1 - 3 8.4 15.3 7.9 7.0 6.0 2.6 1 1 0 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 OAJ05930.1 - 4.7 7.3 12.4 6.8 6.8 4.2 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FliJ PF02050.16 OAJ05930.1 - 6 7.1 15.2 1.9 8.7 2.5 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein DUF2968 PF11180.8 OAJ05930.1 - 8.7 5.9 18.4 1.1 8.9 11.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) zf-CCHC PF00098.23 OAJ05982.1 - 7e-06 25.9 1.7 7e-06 25.9 1.7 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ05982.1 - 0.001 18.8 0.6 0.0017 18.1 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ05982.1 - 0.088 12.5 0.3 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 OAJ05982.1 - 0.23 11.2 0.9 0.4 10.4 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 OAJ05983.1 - 4.4e-16 59.1 0.0 7.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ05983.1 - 4.6e-07 29.6 0.2 9.8e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ05983.1 - 0.00015 21.4 0.2 0.0076 16.0 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain RVT_2 PF07727.14 OAJ05984.1 - 3e-69 233.3 0.0 4.3e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3253 PF11625.8 OAJ05984.1 - 0.009 16.2 0.1 4.7 7.5 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3253) Metallophos PF00149.28 OAJ06096.1 - 4.1e-06 27.4 1.8 5e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Dishevelled PF02377.15 OAJ06096.1 - 0.5 10.8 8.1 0.077 13.5 3.3 2.1 2 0 0 2 2 2 0 Dishevelled specific domain Flavokinase PF01687.17 OAJ06097.1 - 7.7e-31 106.7 0.0 9.6e-31 106.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF3425 PF11905.8 OAJ06160.1 - 2.6e-08 33.9 0.2 1.2e-07 31.7 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAJ06160.1 - 1.6e-07 31.3 5.4 4.5e-07 29.9 5.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ06160.1 - 1.9 8.6 7.7 1 9.5 3.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Phage_integrase PF00589.22 OAJ06161.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Phage integrase family ATP_transf PF09830.9 OAJ06163.1 - 0.00023 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 OAJ06163.1 - 0.018 15.8 0.0 0.056 14.2 0.0 1.8 1 0 0 1 1 1 0 HIT domain RhlB PF12300.8 OAJ06163.1 - 5 7.2 7.1 4.1 7.5 1.0 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB TBP PF00352.21 OAJ06164.1 - 1.4e-67 223.6 0.2 1.6e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAJ06164.1 - 1.2e-05 25.4 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAJ06164.1 - 0.07 13.0 0.2 0.62 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ICL PF00463.21 OAJ06277.1 - 2.1e-19 69.4 0.0 2.4e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PSA_CBD PF18341.1 OAJ06277.1 - 0.027 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 PSA endolysin C-terminal cell wall binding domain DUF3235 PF11574.8 OAJ06277.1 - 0.15 13.0 1.5 3.3 8.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Rad9 PF04139.13 OAJ06278.1 - 5.5e-38 130.8 0.0 1.9e-37 129.1 0.0 1.8 1 1 0 1 1 1 1 Rad9 DUF953 PF06110.11 OAJ06278.1 - 6.2e-17 61.3 0.0 1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 OAJ06278.1 - 0.0042 17.1 0.0 0.061 13.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin Glyco_hydro_45 PF02015.16 OAJ06280.1 - 7.1e-48 163.3 3.1 8.8e-48 163.0 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 KASH PF10541.9 OAJ06280.1 - 0.19 12.0 1.5 0.2 12.0 0.1 1.8 2 0 0 2 2 2 0 Nuclear envelope localisation domain UnbV_ASPIC PF07593.12 OAJ06330.1 - 0.014 15.3 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 ASPIC and UnbV A_deamin PF02137.18 OAJ06333.1 - 1.2e-12 48.0 0.0 2.2e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_L3 PF00297.22 OAJ06401.1 - 2e-182 606.2 7.4 2.3e-182 606.0 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 MCM PF00493.23 OAJ06402.1 - 2.7e-25 88.8 0.0 3.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ06402.1 - 0.00078 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain VWA_2 PF13519.6 OAJ06404.1 - 2.3e-13 50.7 0.1 4.8e-13 49.7 0.1 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OAJ06404.1 - 2.1e-06 28.1 0.3 2.4e-06 27.9 0.3 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAJ06404.1 - 0.011 15.5 0.3 0.014 15.2 0.3 1.0 1 0 0 1 1 1 0 Ssl1-like DUF615 PF04751.14 OAJ06404.1 - 0.064 13.2 0.1 0.076 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) STE3 PF02076.15 OAJ06405.1 - 2.1e-84 283.2 11.5 2.6e-84 282.8 11.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor SKG6 PF08693.10 OAJ06405.1 - 5.4 6.5 0.0 5.4 6.5 0.0 4.9 6 0 0 6 6 6 0 Transmembrane alpha-helix domain Dimer_Tnp_hAT PF05699.14 OAJ06458.1 - 4.8e-15 55.1 0.3 8.1e-15 54.4 0.3 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ06458.1 - 0.00081 19.7 0.1 0.0018 18.6 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) TRIF-NTD PF17798.1 OAJ06458.1 - 0.024 14.7 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 TRIF N-terminal domain SPRY PF00622.28 OAJ06461.1 - 4.1e-21 75.3 0.2 7.6e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 SPRY domain Pkinase PF00069.25 OAJ06581.1 - 1.1e-68 231.5 0.0 1.3e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ06581.1 - 1e-48 165.9 0.0 1.4e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ06581.1 - 2.1e-06 26.8 0.3 8.3e-06 24.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAJ06581.1 - 0.0026 17.1 0.0 0.0092 15.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PRP38_assoc PF12871.7 OAJ06581.1 - 0.025 15.2 1.1 0.025 15.2 1.1 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 OAJ06581.1 - 0.15 10.9 6.5 0.31 9.9 6.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 OAJ06581.1 - 0.33 10.5 10.2 0.81 9.2 10.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box PF00646.33 OAJ06709.1 - 0.0027 17.6 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ06709.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1845 PF08900.11 OAJ06709.1 - 0.1 12.3 0.2 0.16 11.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) DUF2797 PF10977.8 OAJ06709.1 - 0.18 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) HTH_32 PF13565.6 OAJ06774.1 - 8.5e-05 23.1 0.0 0.00029 21.4 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 OAJ06774.1 - 0.0002 21.1 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.15 OAJ06774.1 - 0.032 14.3 0.4 0.18 11.9 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_33 PF13592.6 OAJ06774.1 - 0.05 13.2 1.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DLH PF01738.18 OAJ06777.1 - 1.6e-13 50.8 0.7 1.9e-13 50.5 0.7 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family baeRF_family7 PF18849.1 OAJ06777.1 - 0.1 12.8 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 Podoplanin PF05808.11 OAJ06778.1 - 0.0023 18.1 18.8 0.0062 16.7 15.9 2.4 2 1 0 2 2 2 1 Podoplanin Adeno_E3_CR2 PF02439.15 OAJ06778.1 - 0.36 10.6 3.5 0.65 9.8 3.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TFIIA PF03153.13 OAJ06778.1 - 1.2 9.1 26.5 0.1 12.6 12.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit OAD_gamma PF04277.13 OAJ06850.1 - 0.6 10.7 1.9 1.4 9.6 0.3 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Apt1 PF10351.9 OAJ06851.1 - 0.016 14.1 6.2 0.018 13.9 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 OAJ06851.1 - 0.046 12.5 2.0 0.057 12.2 2.0 1.2 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 OAJ06851.1 - 0.13 10.5 6.2 0.16 10.2 6.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SSP160 PF06933.11 OAJ06851.1 - 0.23 9.6 35.6 0.035 12.3 18.6 3.0 2 1 1 3 3 3 0 Special lobe-specific silk protein SSP160 SPX PF03105.19 OAJ06851.1 - 0.29 11.0 9.1 0.36 10.7 9.1 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 OAJ06851.1 - 0.67 9.1 19.6 0.87 8.7 19.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hid1 PF12722.7 OAJ06851.1 - 0.76 7.8 6.6 0.93 7.5 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 OAJ06851.1 - 0.86 8.3 3.1 1.1 8.0 3.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 OAJ06851.1 - 1 9.1 10.4 1.6 8.5 10.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein SBE2 PF17076.5 OAJ06851.1 - 3.2 5.8 7.9 3.7 5.6 7.9 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Pox_Ag35 PF03286.14 OAJ06855.1 - 1.3 8.8 12.1 0.89 9.3 7.1 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 OAJ06855.1 - 1.4 9.3 13.1 0.042 14.2 6.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_3_Rpc31 PF11705.8 OAJ06855.1 - 6.1 7.0 15.8 20 5.3 10.2 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cys_Met_Meta_PP PF01053.20 OAJ06924.1 - 3.6e-53 180.5 0.0 1.6e-46 158.6 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAJ06924.1 - 0.067 12.1 0.1 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ06924.1 - 0.099 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II bZIP_1 PF00170.21 OAJ06983.1 - 0.00012 22.1 9.7 0.00012 22.1 9.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor Kinesin_assoc PF16183.5 OAJ06983.1 - 0.00068 19.8 0.2 0.00068 19.8 0.2 2.8 3 0 0 3 3 3 1 Kinesin-associated Ino80_Iec3 PF14612.6 OAJ06983.1 - 0.016 15.9 0.5 0.016 15.9 0.5 3.0 2 1 1 3 3 3 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF702 PF05142.12 OAJ06983.1 - 2.5 8.6 9.2 2.2 8.8 3.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Roughex PF06020.11 OAJ06983.1 - 9.2 5.2 7.8 19 4.2 7.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DENN PF02141.21 OAJ06985.1 - 5.5e-22 78.6 0.0 9.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain APG6_N PF17675.1 OAJ06985.1 - 0.14 12.7 13.9 0.04 14.5 9.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 OAJ06985.1 - 0.27 10.5 15.0 0.11 11.9 10.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 OAJ06985.1 - 0.67 8.5 2.0 1.5 7.3 2.0 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 OAJ06985.1 - 0.75 8.6 16.1 0.04 12.8 10.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein SF-assemblin PF06705.11 OAJ06985.1 - 0.91 8.8 11.9 0.12 11.7 6.2 2.0 2 0 0 2 2 2 0 SF-assemblin/beta giardin Tektin PF03148.14 OAJ06985.1 - 1.1 7.9 18.6 1.7 7.3 11.4 2.8 2 1 1 3 3 3 0 Tektin family SWIRM-assoc_1 PF16495.5 OAJ06985.1 - 2.2 8.3 13.5 0.27 11.2 8.5 2.1 2 0 0 2 2 2 0 SWIRM-associated region 1 DUF724 PF05266.14 OAJ06985.1 - 2.5 7.9 16.0 0.27 11.0 10.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 OAJ06985.1 - 2.9 6.4 10.0 0.97 8.0 4.5 2.0 2 0 0 2 2 2 0 AAA domain IFT20 PF14931.6 OAJ06985.1 - 2.9 8.1 12.4 0.079 13.1 5.9 1.8 2 0 0 2 2 1 0 Intraflagellar transport complex B, subunit 20 Filament PF00038.21 OAJ06985.1 - 3.4 7.2 20.9 0.15 11.6 11.7 2.6 2 1 1 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.12 OAJ06985.1 - 3.8 7.5 5.5 20 5.2 0.2 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 OAJ06985.1 - 4.7 6.9 13.7 0.37 10.5 7.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Cluap1 PF10234.9 OAJ06985.1 - 5.8 6.2 13.5 0.43 9.9 6.2 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 Phage_GPO PF05929.11 OAJ06985.1 - 7.8 6.0 10.8 0.7 9.5 4.1 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Golgin_A5 PF09787.9 OAJ06985.1 - 7.9 5.9 19.3 0.26 10.7 9.7 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Atg14 PF10186.9 OAJ06985.1 - 8.6 5.3 14.9 14 4.7 6.9 2.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 OAJ06985.1 - 9.1 5.5 16.0 0.5 9.6 9.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Coatomer_WDAD PF04053.14 OAJ07148.1 - 2.2e-127 425.8 0.1 1.9e-96 323.8 0.0 2.8 2 1 1 3 3 3 2 Coatomer WD associated region WD40 PF00400.32 OAJ07148.1 - 2.3e-28 97.8 9.0 3.3e-06 27.7 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAJ07148.1 - 0.0017 17.1 1.3 0.65 8.6 0.5 3.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Phlebovirus_G2 PF07245.11 OAJ07148.1 - 0.13 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Spt5_N PF11942.8 OAJ07221.1 - 0.036 15.0 11.6 0.067 14.2 11.6 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF874 PF05917.11 OAJ07221.1 - 0.048 12.7 7.9 0.063 12.3 7.9 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) CDC45 PF02724.14 OAJ07221.1 - 0.11 10.8 6.5 0.14 10.4 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAJ07221.1 - 0.38 9.5 5.9 0.4 9.4 5.9 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OAJ07221.1 - 0.61 8.1 3.9 0.56 8.3 3.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TERB2 PF15101.6 OAJ07221.1 - 0.89 9.6 7.6 1.4 8.9 7.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 OAJ07221.1 - 1.1 9.3 6.8 1.4 8.9 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2072 PF09845.9 OAJ07221.1 - 2 8.7 8.7 1.5 9.1 6.7 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein Coilin_N PF15862.5 OAJ07221.1 - 5.3 6.8 17.3 2.4 7.9 14.5 1.7 2 0 0 2 2 2 0 Coilin N-terminus PTPRCAP PF15713.5 OAJ07221.1 - 9.8 6.5 14.2 15 5.9 14.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF5635 PF18685.1 OAJ07298.1 - 0.079 12.9 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Glypican PF01153.19 OAJ07299.1 - 0.43 9.4 1.4 0.58 8.9 1.4 1.1 1 0 0 1 1 1 0 Glypican CDC45 PF02724.14 OAJ07299.1 - 1.7 6.8 9.2 2.2 6.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PrpF PF04303.13 OAJ07382.1 - 1e-47 162.9 0.2 1.5e-33 116.3 0.0 2.5 2 1 0 2 2 2 2 PrpF protein SAT PF16073.5 OAJ07382.1 - 0.074 12.8 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ribosomal_L2_C PF03947.18 OAJ07383.1 - 3.9e-49 166.0 6.3 2.2e-48 163.6 6.3 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAJ07383.1 - 3.2e-25 87.9 0.1 7.2e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.16 OAJ07388.1 - 2.5e-18 66.2 35.4 2.5e-18 66.2 35.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5367 PF17329.2 OAJ07388.1 - 0.002 18.2 3.3 0.002 18.2 3.3 3.0 3 0 0 3 3 3 1 Family of unknown function (DUF5367) Nterm_IS4 PF13006.7 OAJ07388.1 - 0.043 14.0 0.0 18 5.6 0.0 2.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal Sugar_tr PF00083.24 OAJ07388.1 - 2.3 7.0 30.9 0.011 14.7 15.2 3.3 2 2 0 2 2 2 0 Sugar (and other) transporter COesterase PF00135.28 OAJ07390.1 - 9.9e-95 318.3 0.1 2e-94 317.3 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ07390.1 - 2.4e-05 24.3 0.3 0.033 14.1 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Mtc PF03820.17 OAJ07391.1 - 1.3e-102 343.1 0.0 1.4e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier gag_pre-integrs PF13976.6 OAJ07478.1 - 9.2e-07 28.6 0.4 2.4e-05 24.1 0.1 3.0 2 1 1 3 3 3 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ07480.1 - 6.4e-05 22.8 1.2 0.00015 21.7 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ07480.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Calcipressin PF04847.12 OAJ07567.1 - 3.1e-24 85.8 0.0 2.2e-20 73.2 0.4 2.3 2 0 0 2 2 2 2 Calcipressin Septin PF00735.18 OAJ07568.1 - 1.6e-114 381.9 0.4 2.2e-114 381.5 0.4 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ07568.1 - 2.5e-09 37.2 0.0 6.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ07568.1 - 2.1e-08 34.2 0.3 4.6e-07 29.9 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ07568.1 - 1.2e-06 28.2 3.1 6e-05 22.7 0.1 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 OAJ07568.1 - 3.4e-05 24.0 0.2 8.1e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ07568.1 - 5.6e-05 22.8 0.6 0.00017 21.2 0.6 1.8 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 OAJ07568.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 OAJ07568.1 - 0.0005 20.5 1.1 0.0007 20.0 0.2 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ07568.1 - 0.00063 20.0 1.7 0.0011 19.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAJ07568.1 - 0.0013 19.3 0.2 0.0041 17.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 OAJ07568.1 - 0.0029 17.4 1.6 0.05 13.4 0.2 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OAJ07568.1 - 0.0063 15.9 0.1 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OAJ07568.1 - 0.015 14.8 0.1 0.043 13.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 OAJ07568.1 - 0.015 14.8 0.1 0.04 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 OAJ07568.1 - 0.016 14.7 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAJ07568.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 OAJ07568.1 - 0.019 14.8 0.6 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 OAJ07568.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 OAJ07568.1 - 0.028 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 OAJ07568.1 - 0.029 14.4 4.8 0.58 10.2 0.2 2.8 2 1 1 3 3 3 0 Dynamin family Mg_chelatase PF01078.21 OAJ07568.1 - 0.047 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 OAJ07568.1 - 0.048 12.7 0.6 0.33 10.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAJ07568.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 OAJ07568.1 - 0.06 13.4 0.6 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OAJ07568.1 - 0.061 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 OAJ07568.1 - 0.093 13.1 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase FOXP-CC PF16159.5 OAJ07568.1 - 0.11 13.2 0.5 0.4 11.3 0.5 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain AAA_24 PF13479.6 OAJ07568.1 - 0.11 12.2 6.5 0.11 12.2 0.8 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ07568.1 - 0.57 9.7 5.7 0.71 9.4 0.5 2.6 2 1 1 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 OAJ07571.1 - 4.1e-48 163.4 0.0 8.2e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ07571.1 - 1.4e-26 93.0 0.1 5.3e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ07571.1 - 5.8e-18 64.9 0.0 1.8e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ07571.1 - 2.7e-07 30.7 0.0 6.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ07571.1 - 0.00032 20.0 0.2 0.00073 18.8 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF3391 PF11871.8 OAJ07571.1 - 7.8 7.0 7.3 0.92 10.0 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Big_3_2 PF12245.8 OAJ07636.1 - 0.023 15.0 0.1 0.028 14.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain DUF2551 PF10826.8 OAJ07636.1 - 0.039 14.2 0.5 0.049 13.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2551) Asp_protease_2 PF13650.6 OAJ07637.1 - 2.5e-05 24.8 0.3 3.8e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ07637.1 - 0.0098 16.4 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease MAGI_u5 PF16666.5 OAJ07637.1 - 0.038 14.1 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 Unstructured region on MAGI RVP PF00077.20 OAJ07637.1 - 0.046 14.0 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 OAJ07638.1 - 1.7e-23 83.3 0.0 2.8e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ07638.1 - 1.4e-15 57.1 0.1 2.9e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ07638.1 - 4.7e-15 55.5 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ07638.1 - 3.3e-09 37.0 0.0 9.5e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ07638.1 - 0.00035 20.8 0.0 0.0008 19.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TEBP_beta PF07404.11 OAJ07717.1 - 0.14 11.5 4.5 0.25 10.7 4.5 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Atg14 PF10186.9 OAJ07717.1 - 0.25 10.4 17.2 0.032 13.3 9.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 OAJ07717.1 - 0.27 11.9 12.3 2.9 8.6 0.0 3.6 3 0 0 3 3 3 0 SlyX BRE1 PF08647.11 OAJ07717.1 - 0.28 11.3 17.5 0.047 13.8 2.2 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 OAJ07717.1 - 0.35 11.3 3.8 3 8.4 0.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 OAJ07717.1 - 1.5 8.2 19.1 3.2 7.1 12.7 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HALZ PF02183.18 OAJ07717.1 - 2 8.7 4.6 3.4 8.0 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med9 PF07544.13 OAJ07717.1 - 2.4 8.3 6.3 21 5.3 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.20 OAJ07717.1 - 2.5 8.1 12.8 7.7 6.5 1.6 3.2 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 OAJ07717.1 - 2.7 7.8 20.4 0.29 10.9 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 OAJ07717.1 - 3.2 7.8 16.3 2 8.5 9.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OAJ07717.1 - 3.4 8.2 30.2 1.3 9.5 2.4 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region She9_MDM33 PF05546.11 OAJ07717.1 - 3.7 7.3 12.7 0.98 9.2 0.3 2.4 2 0 0 2 2 2 0 She9 / Mdm33 family TolA_bind_tri PF16331.5 OAJ07717.1 - 4.8 7.3 17.3 2 8.6 0.3 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 OAJ07717.1 - 5 7.2 19.1 1.5 8.9 1.1 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SPATA1_C PF15743.5 OAJ07717.1 - 5.4 7.1 12.4 0.48 10.5 0.3 2.8 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus Latarcin PF10279.9 OAJ07717.1 - 5.7 7.4 7.0 5.7 7.4 0.4 2.5 2 0 0 2 2 2 0 Latarcin precursor MscS_porin PF12795.7 OAJ07717.1 - 6.6 6.2 30.0 0.47 10.0 19.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FH2 PF02181.23 OAJ07717.1 - 9.1 5.3 9.3 0.27 10.3 1.3 2.2 2 1 0 3 3 3 0 Formin Homology 2 Domain V_ATPase_I PF01496.19 OAJ07717.1 - 9.3 4.0 7.9 6.2 4.6 4.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 OAJ07717.1 - 9.3 6.6 24.6 0.13 12.6 1.2 3.3 2 1 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SurE PF01975.17 OAJ07718.1 - 0.066 13.0 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Survival protein SurE DUF758 PF05527.11 OAJ07718.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF758) CAP PF00188.26 OAJ07724.1 - 6.4e-21 75.5 4.0 7.2e-21 75.3 2.4 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family TAP42 PF04177.12 OAJ07815.1 - 8.2e-66 222.3 0.0 1.1e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 TAP42-like family SUIM_assoc PF16619.5 OAJ07815.1 - 0.023 14.7 3.8 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CDT1_C PF16679.5 OAJ07815.1 - 0.6 10.6 0.1 0.6 10.6 0.1 2.4 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain CAP_N PF01213.19 OAJ07815.1 - 1.7 8.1 11.1 0.018 14.6 2.7 1.9 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal NAD_binding_10 PF13460.6 OAJ07816.1 - 6.4e-25 88.1 0.0 8.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ07816.1 - 0.00023 20.7 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAJ07816.1 - 0.0033 17.0 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Phage_tail_APC PF16778.5 OAJ07816.1 - 0.0038 17.1 0.3 3 7.8 0.2 2.8 3 1 0 3 3 3 2 Phage tail assembly chaperone protein NAD_binding_4 PF07993.12 OAJ07816.1 - 0.18 10.9 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Mito_carr PF00153.27 OAJ07819.1 - 4.6e-65 215.6 2.6 1.1e-21 76.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AIM5 PF17050.5 OAJ07820.1 - 3.8e-05 24.4 3.6 4.5e-05 24.2 0.9 2.2 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF883 PF05957.13 OAJ07820.1 - 0.051 14.2 0.7 0.051 14.2 0.7 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Vac14_Fab1_bd PF12755.7 OAJ07907.1 - 3.8e-07 30.6 0.1 0.00028 21.4 0.0 3.0 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region Dimer_Tnp_hAT PF05699.14 OAJ07910.1 - 1.3e-08 34.5 0.0 3.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.27 OAJ08017.1 - 1.1e-23 84.0 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08017.1 - 3.5e-19 68.7 0.0 9.3e-13 48.1 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08017.1 - 6.8e-16 58.1 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ08017.1 - 1.1e-14 54.5 0.0 2.9e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08017.1 - 1.7e-11 44.3 0.0 4.6e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08017.1 - 0.00013 22.6 0.0 0.00042 20.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08017.1 - 0.00077 20.0 0.0 0.0024 18.4 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ08017.1 - 0.016 15.4 0.0 0.063 13.5 0.0 2.1 1 0 0 1 1 1 0 H2C2 zinc finger MKT1_C PF12246.8 OAJ08019.1 - 1.1e-75 254.0 0.0 1.9e-74 249.9 0.0 2.4 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 OAJ08019.1 - 6.9e-23 80.8 0.0 1.6e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 OAJ08019.1 - 6.7e-08 32.9 0.0 1.9e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Spt20 PF12090.8 OAJ08019.1 - 1.5 8.4 10.9 31 4.1 9.9 2.5 2 0 0 2 2 2 0 Spt20 family PB1 PF00564.24 OAJ08020.1 - 5.2e-05 23.1 0.3 9.6e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 PB1 domain CBS PF00571.28 OAJ08020.1 - 0.055 13.9 0.8 0.13 12.8 0.1 1.8 2 0 0 2 2 2 0 CBS domain SelP_N PF04592.14 OAJ08020.1 - 0.1 12.0 8.3 0.14 11.6 8.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMN PF06003.12 OAJ08020.1 - 9.5 5.4 9.3 12 5.1 9.3 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TPR_2 PF07719.17 OAJ08025.1 - 1.9e-07 30.7 5.7 0.02 15.0 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ08025.1 - 7.6e-06 25.5 6.8 0.019 14.8 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ08025.1 - 0.00015 21.7 3.5 0.12 12.7 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ08025.1 - 0.00038 20.5 0.6 2.1 8.4 0.2 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 OAJ08025.1 - 0.00095 19.4 22.7 0.1 12.9 1.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ08025.1 - 0.0048 16.9 8.1 0.019 15.0 0.1 4.5 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 5 NRDE-2 PF08424.10 OAJ08025.1 - 0.024 13.8 0.4 0.038 13.1 0.4 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 OAJ08025.1 - 0.044 13.8 2.6 10 6.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1204 PF06721.11 OAJ08025.1 - 0.049 13.1 0.3 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) ANAPC3 PF12895.7 OAJ08025.1 - 0.052 13.8 0.5 7.4 6.9 0.0 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 OAJ08025.1 - 0.066 13.2 0.2 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_14 PF13428.6 OAJ08025.1 - 0.47 11.4 0.0 0.47 11.4 0.0 7.3 7 2 2 9 9 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ08025.1 - 0.48 11.2 21.4 1.9 9.3 0.1 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ08025.1 - 1.9 9.0 13.3 3.2 8.4 0.8 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat RPN13_C PF16550.5 OAJ08026.1 - 0.045 13.9 0.1 0.061 13.5 0.1 1.3 1 0 0 1 1 1 0 UCH-binding domain CDH-cyt PF16010.5 OAJ08030.1 - 9.6e-11 41.7 2.0 4.6e-10 39.5 2.0 1.9 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 OAJ08030.1 - 0.0018 18.5 0.1 0.0029 17.8 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 OAJ08030.1 - 0.095 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) UCH PF00443.29 OAJ08035.1 - 1.2e-35 123.3 0.0 2.1e-34 119.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ08035.1 - 1.7e-06 27.9 0.0 0.002 17.8 0.0 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase OapA_N PF08525.11 OAJ08035.1 - 0.66 10.0 4.9 1.8 8.6 4.9 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Ras PF00071.22 OAJ08036.1 - 8.7e-52 175.0 0.3 1e-51 174.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ08036.1 - 5.2e-31 107.4 0.1 6.9e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ08036.1 - 4.2e-16 58.9 0.0 6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ08036.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ08036.1 - 0.00028 20.3 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAJ08036.1 - 0.0014 18.1 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAJ08036.1 - 0.0026 17.3 0.3 0.012 15.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OAJ08036.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein HTH_DeoR PF08220.12 OAJ08038.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Nop14 PF04147.12 OAJ08039.1 - 0.00058 18.2 17.7 0.00071 17.9 17.7 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 OAJ08039.1 - 0.0068 16.5 23.3 0.0068 16.5 23.3 2.0 1 1 1 2 2 2 1 YL1 nuclear protein TFIIA PF03153.13 OAJ08039.1 - 0.015 15.4 16.2 0.021 14.8 16.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.18 OAJ08039.1 - 0.069 13.0 7.2 0.096 12.6 7.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF4746 PF15928.5 OAJ08039.1 - 0.25 10.8 5.1 0.4 10.1 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 OAJ08039.1 - 0.95 9.0 20.8 0.095 12.3 16.3 1.5 2 0 0 2 2 2 0 PPP4R2 FYDLN_acid PF09538.10 OAJ08039.1 - 1 10.0 18.9 3.3 8.4 18.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 OAJ08039.1 - 1.1 7.3 27.9 1.5 6.8 27.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 OAJ08039.1 - 1.3 8.6 19.6 1 9.0 18.5 1.4 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Astro_capsid_p PF12226.8 OAJ08039.1 - 4.1 6.5 22.4 6.1 5.9 22.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-CCHC PF00098.23 OAJ08040.1 - 0.00098 19.1 2.1 0.0015 18.5 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 OAJ08040.1 - 0.033 14.6 1.0 0.11 12.9 1.0 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Retrotrans_gag PF03732.17 OAJ08040.1 - 0.072 13.4 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 OAJ08040.1 - 0.12 12.4 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ08040.1 - 0.49 10.3 4.1 1.4 8.8 4.1 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 OAJ08043.1 - 2.1e-14 53.6 0.0 8.6e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ08043.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease P_C10 PF14974.6 OAJ08043.1 - 0.093 12.8 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein C10 zf-CCHC PF00098.23 OAJ08043.1 - 0.13 12.4 3.6 0.062 13.4 1.2 1.7 2 0 0 2 2 2 0 Zinc knuckle Integrase_H2C2 PF17921.1 OAJ08045.1 - 3.6e-21 75.0 0.5 3.6e-21 75.0 0.5 1.5 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OAJ08045.1 - 0.0016 18.6 0.1 0.0039 17.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger gag_pre-integrs PF13976.6 OAJ08045.1 - 0.049 13.5 0.1 3.7 7.5 0.0 2.9 3 0 0 3 3 3 0 GAG-pre-integrase domain Sec20 PF03908.13 OAJ08047.1 - 5.5e-19 67.9 1.3 1.3e-18 66.7 1.3 1.6 1 0 0 1 1 1 1 Sec20 DAHP_synth_1 PF00793.20 OAJ08048.1 - 1.2e-99 332.7 0.0 1.4e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RT_RNaseH_2 PF17919.1 OAJ08055.1 - 2e-23 82.3 0.1 1.9e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08055.1 - 1.5e-18 67.0 0.0 5.2e-12 46.0 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08055.1 - 1.1e-16 61.0 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08055.1 - 6.1e-16 58.3 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08055.1 - 3e-10 40.3 0.0 7.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DcpS_C PF11969.8 OAJ08058.1 - 2.6e-27 95.6 0.1 3.9e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 OAJ08058.1 - 1.3e-15 58.1 0.0 2.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF5075 PF16825.5 OAJ08058.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 IGP family C-type lectin domain Abhydrolase_6 PF12697.7 OAJ08060.1 - 1.7e-13 51.7 0.2 2.5e-13 51.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ08060.1 - 8.1e-08 32.2 0.1 1.8e-07 31.1 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ08060.1 - 2.1e-07 30.5 0.0 4.4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Med14 PF08638.11 OAJ08064.1 - 0.018 14.5 0.5 0.045 13.2 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit MED14 Mod_r PF07200.13 OAJ08064.1 - 0.028 14.5 2.6 0.76 9.9 1.2 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RhlB PF12300.8 OAJ08064.1 - 3.4 7.8 13.1 2.1 8.4 7.0 2.5 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Hydrolase_like PF13242.6 OAJ08069.1 - 1.2e-22 79.8 0.0 1.5e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAJ08069.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAM176 PF14851.6 OAJ08070.1 - 0.92 9.2 2.9 19 4.9 0.3 2.5 3 0 0 3 3 3 0 FAM176 family MARVEL PF01284.23 OAJ08071.1 - 4.2 7.4 14.1 9.2 6.3 14.1 1.6 1 0 0 1 1 1 0 Membrane-associating domain Corona_nucleoca PF00937.18 OAJ08071.1 - 7.4 5.5 12.5 2.8 6.9 10.0 1.5 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein Herpes_UL32 PF06070.11 OAJ08073.1 - 0.47 8.1 3.3 0.58 7.8 3.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HEM4 PF02602.15 OAJ08077.1 - 1.8e-18 66.7 0.5 3.8e-09 36.2 0.1 4.7 5 0 0 5 5 5 4 Uroporphyrinogen-III synthase HemD DEAD PF00270.29 OAJ08078.1 - 7.8e-15 55.1 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ08078.1 - 5.7e-12 46.0 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ08078.1 - 5.4e-06 26.7 0.2 4.8e-05 23.7 0.0 2.4 2 1 1 3 3 3 1 AAA domain SNF2_N PF00176.23 OAJ08078.1 - 0.0016 17.3 1.4 0.0023 16.7 1.2 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 OAJ08078.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAJ08078.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Acetyltransf_11 PF13720.6 OAJ08078.1 - 0.18 12.3 0.2 0.72 10.4 0.2 2.0 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase PF00069.25 OAJ08083.1 - 2.6e-23 82.8 0.3 3e-20 72.7 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08083.1 - 2.1e-15 56.7 0.0 7.1e-13 48.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 OAJ08084.1 - 8.8e-08 32.4 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 OAJ08084.1 - 1.4e-07 31.7 4.8 1.4e-07 31.7 4.8 2.8 3 0 0 3 3 3 1 Ring finger domain IBR PF01485.21 OAJ08084.1 - 2.8e-07 30.6 17.0 3.2e-07 30.5 0.8 3.3 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OAJ08084.1 - 6.5e-06 26.1 5.3 6.5e-06 26.1 5.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ08084.1 - 5.6e-05 23.0 7.0 5.6e-05 23.0 7.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAJ08084.1 - 0.00014 21.5 6.0 0.00031 20.4 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAJ08084.1 - 0.00014 21.6 6.5 0.00014 21.6 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ08084.1 - 0.00061 19.6 4.5 0.00061 19.6 4.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ08084.1 - 0.0039 17.0 3.1 0.015 15.2 3.1 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAJ08084.1 - 0.022 14.9 1.2 0.022 14.9 1.2 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAJ08084.1 - 0.27 11.1 11.9 0.23 11.3 1.3 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OAJ08084.1 - 6.4 6.7 14.0 0.26 11.2 6.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ParA PF10609.9 OAJ08085.1 - 1.2e-82 277.0 0.0 3.4e-81 272.3 0.0 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ08085.1 - 4.1e-06 26.9 0.6 4.5e-05 23.5 0.9 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAJ08085.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 OAJ08085.1 - 0.0006 19.8 0.0 0.023 14.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OAJ08085.1 - 0.00081 18.7 2.0 0.0027 16.9 0.4 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OAJ08085.1 - 0.01 15.6 0.1 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ08085.1 - 0.016 15.6 0.1 0.036 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain CBP_BcsQ PF06564.12 OAJ08085.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 OAJ08085.1 - 0.026 14.4 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 OAJ08085.1 - 0.17 12.3 0.0 0.53 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase SfLAP PF11139.8 OAJ08093.1 - 0.00044 19.8 2.0 0.00044 19.8 2.0 2.4 3 0 0 3 3 3 1 Sap, sulfolipid-1-addressing protein DUF3341 PF11821.8 OAJ08093.1 - 5.8 6.5 7.5 7.6 6.1 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) RVT_1 PF00078.27 OAJ08098.1 - 6.2e-23 81.5 0.0 9e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ08098.1 - 0.0008 20.0 0.1 0.003 18.2 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08098.1 - 0.015 15.9 0.0 0.062 13.9 0.0 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.13 OAJ08098.1 - 0.042 12.6 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein RNase_H PF00075.24 OAJ08101.1 - 3.5e-08 33.7 0.1 8.1e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 RNase H rve PF00665.26 OAJ08106.1 - 2.7e-06 27.6 0.0 4.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Pyr_redox_2 PF07992.14 OAJ08108.1 - 0.023 13.9 0.1 0.12 11.6 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 OAJ08112.1 - 4.1e-19 68.6 11.5 7e-06 26.7 0.9 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08112.1 - 8.7e-05 22.8 0.0 0.84 10.0 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 OAJ08121.1 - 6.8e-22 78.1 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08121.1 - 1.3e-16 60.4 0.0 2.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ08121.1 - 2.2e-15 56.5 0.0 8.6e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08121.1 - 1.1e-07 32.1 0.0 3.6e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08121.1 - 0.00031 20.9 0.0 0.00075 19.7 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ08121.1 - 0.0023 18.2 0.0 0.0068 16.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Exc PF07825.11 OAJ08121.1 - 0.55 10.3 2.9 0.49 10.4 0.6 2.1 2 0 0 2 2 2 0 Excisionase-like protein Asp_protease_2 PF13650.6 OAJ08123.1 - 6.2e-05 23.6 0.0 0.00019 22.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08123.1 - 0.001 19.6 0.0 0.004 17.7 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2849 PF11011.8 OAJ08123.1 - 0.026 15.2 0.1 0.76 10.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) Zn_protease PF05618.11 OAJ08123.1 - 0.043 13.7 1.0 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Putative ATP-dependant zinc protease dUTPase PF00692.19 OAJ08123.1 - 0.083 12.6 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 dUTPase DUF2528 PF10800.8 OAJ08125.1 - 0.22 12.1 0.0 0.41 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Actin PF00022.19 OAJ08131.1 - 1.9e-16 59.7 0.3 8.9e-16 57.5 0.3 1.8 1 1 0 1 1 1 1 Actin RVT_2 PF07727.14 OAJ08140.1 - 1.1e-65 221.7 0.0 1.5e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08140.1 - 1.2e-19 70.7 0.0 2.6e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ08140.1 - 0.00065 19.4 0.0 0.002 17.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08140.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ08141.1 - 9.8e-06 25.4 6.1 1.7e-05 24.6 6.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ08141.1 - 0.037 14.0 6.4 0.063 13.2 6.4 1.4 1 0 0 1 1 1 0 Zinc knuckle GRP PF07172.11 OAJ08141.1 - 0.054 14.2 15.5 0.072 13.8 15.5 1.3 1 0 0 1 1 1 0 Glycine rich protein family SWIM PF04434.17 OAJ08143.1 - 0.00015 21.3 0.2 0.0003 20.4 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger EPSP_synthase PF00275.20 OAJ08144.1 - 0.0035 16.1 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) CHAT PF12770.7 OAJ08144.1 - 0.048 13.1 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 CHAT domain zf-C2H2_aberr PF17017.5 OAJ08148.1 - 9.3e-05 22.6 5.5 0.11 12.7 0.3 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OAJ08148.1 - 0.0082 16.6 7.9 0.5 10.9 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ08148.1 - 0.68 10.9 12.9 6.4 7.9 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ08148.1 - 0.95 10.0 6.4 9.4 6.9 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DUF1631 PF07793.11 OAJ08148.1 - 6.6 5.0 8.9 11 4.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FOXP-CC PF16159.5 OAJ08148.1 - 6.7 7.4 5.9 15 6.3 0.9 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain Sterol_MT_C PF08498.10 OAJ08150.1 - 7.5e-28 96.6 0.2 1.3e-27 95.9 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAJ08150.1 - 2.1e-17 63.5 0.0 3.9e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ08150.1 - 2.7e-17 63.0 0.0 3.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ08150.1 - 9.9e-17 61.4 0.2 2.4e-16 60.2 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 OAJ08150.1 - 1.7e-14 53.8 0.0 2.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAJ08150.1 - 1.3e-13 51.1 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ08150.1 - 5.6e-13 49.5 0.3 1.8e-11 44.7 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain PCMT PF01135.19 OAJ08150.1 - 2.6e-05 24.1 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 OAJ08150.1 - 0.00018 22.5 0.0 0.00059 20.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OAJ08150.1 - 0.00065 19.3 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 OAJ08150.1 - 0.00067 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OAJ08150.1 - 0.0029 16.9 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 OAJ08150.1 - 0.0036 16.7 0.0 0.0084 15.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.17 OAJ08150.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_32 PF13679.6 OAJ08150.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 OAJ08150.1 - 0.027 13.6 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.18 OAJ08150.1 - 0.034 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 OAJ08150.1 - 0.036 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 OAJ08150.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase HRM PF02793.22 OAJ08150.1 - 0.068 13.5 1.1 0.15 12.3 1.1 1.5 1 0 0 1 1 1 0 Hormone receptor domain Methyltransf_18 PF12847.7 OAJ08150.1 - 0.15 12.0 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain SSF PF00474.17 OAJ08151.1 - 6.2e-24 84.6 34.4 6.2e-24 84.6 34.4 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Ribosomal_L10 PF00466.20 OAJ08154.1 - 0.001 19.2 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 DUF2169 PF09937.9 OAJ08154.1 - 0.093 12.2 0.5 0.16 11.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Transket_pyr PF02779.24 OAJ08156.1 - 3.3e-37 127.9 0.0 5.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAJ08156.1 - 2e-27 95.6 0.0 1.6e-26 92.6 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_S5 PF00333.20 OAJ08156.1 - 0.21 11.6 0.5 18 5.4 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Ras PF00071.22 OAJ08159.1 - 3.7e-65 218.5 0.0 4.3e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ08159.1 - 6.4e-34 116.7 0.1 9.7e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ08159.1 - 2.4e-13 49.9 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ08159.1 - 7.5e-05 22.3 0.0 0.00019 21.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ08159.1 - 0.00022 20.7 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ08159.1 - 0.00028 21.0 0.0 0.00051 20.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ08159.1 - 0.00036 20.5 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OAJ08159.1 - 0.035 13.6 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAJ08159.1 - 0.038 14.4 0.0 0.057 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 OAJ08159.1 - 0.053 12.6 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 OAJ08159.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 OAJ08159.1 - 0.058 12.9 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 OAJ08159.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OAJ08159.1 - 0.081 13.3 0.1 0.95 9.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OAJ08159.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OAJ08159.1 - 0.21 11.1 0.0 0.49 9.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Leuk-A4-hydro_C PF09127.11 OAJ08160.1 - 6.7e-37 126.0 0.0 1.2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.20 OAJ08160.1 - 4.1e-34 118.0 0.0 5.8e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAJ08160.1 - 1.6e-22 80.6 0.0 2.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NARP1 PF12569.8 OAJ08169.1 - 2.1 7.2 8.1 3 6.6 8.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 OAJ08169.1 - 8.7 6.8 11.2 2.6 8.5 5.9 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 MFS_1 PF07690.16 OAJ08170.1 - 2.3e-36 125.5 40.9 2.3e-36 125.5 40.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ08170.1 - 5.9e-09 35.3 8.2 5.9e-09 35.3 8.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter RT_RNaseH PF17917.1 OAJ08173.1 - 1.6e-10 41.2 0.0 2.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ08173.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08174.1 - 1.4e-25 90.1 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08174.1 - 1.4e-15 57.2 0.3 2.7e-15 56.2 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ08174.1 - 4.6e-14 52.3 0.0 9.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08174.1 - 8.8e-10 38.8 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08174.1 - 0.00025 21.6 0.0 0.00067 20.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ08174.1 - 0.0071 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ08174.1 - 0.041 14.4 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PUB_1 PF18486.1 OAJ08176.1 - 0.0047 16.8 0.4 0.01 15.7 0.1 1.8 2 0 0 2 2 2 1 PNGase/UBA- or UBX-containing domain Ras PF00071.22 OAJ08181.1 - 8.3e-32 110.0 0.0 1.3e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Tannase PF07519.11 OAJ08181.1 - 1e-08 34.5 0.5 1.5e-08 34.0 0.5 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Roc PF08477.13 OAJ08181.1 - 3.4e-08 33.7 0.0 7.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAJ08181.1 - 0.048 13.2 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Phage_integrase PF00589.22 OAJ08183.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family RVT_1 PF00078.27 OAJ08184.1 - 0.0041 16.7 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4614 PF15391.6 OAJ08188.1 - 0.037 14.0 9.7 0.037 14.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 OAJ08188.1 - 0.083 11.4 8.1 0.076 11.6 8.1 1.0 1 0 0 1 1 1 0 Macoilin family LCD1 PF09798.9 OAJ08188.1 - 0.11 11.0 2.7 0.11 11.0 2.7 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Asp_protease_2 PF13650.6 OAJ08188.1 - 0.13 13.0 0.4 0.27 11.9 0.1 1.7 1 1 0 2 2 2 0 Aspartyl protease Apt1 PF10351.9 OAJ08188.1 - 0.41 9.4 9.2 0.39 9.5 9.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec3_C PF09763.9 OAJ08188.1 - 3.6 5.9 7.7 3.7 5.8 7.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 PKcGMP_CC PF16808.5 OAJ08189.1 - 0.0012 18.6 16.3 0.0014 18.5 0.7 4.3 4 0 0 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase PRKG1_interact PF15898.5 OAJ08189.1 - 0.013 16.4 6.6 0.013 16.4 6.6 3.9 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4200 PF13863.6 OAJ08189.1 - 0.015 15.7 8.3 0.015 15.7 8.3 4.3 3 1 2 5 5 5 0 Domain of unknown function (DUF4200) DivIC PF04977.15 OAJ08189.1 - 0.015 15.0 6.0 0.015 15.0 6.0 5.9 5 1 2 7 7 6 0 Septum formation initiator KASH_CCD PF14662.6 OAJ08189.1 - 0.15 11.9 38.9 0.28 11.0 23.8 3.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4763 PF15960.5 OAJ08189.1 - 1 8.6 21.7 0.34 10.2 6.1 3.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4763) TMEM171 PF15471.6 OAJ08189.1 - 4 6.3 0.0 4 6.3 0.0 2.9 3 0 0 3 3 3 0 Transmembrane protein family 171 AAA_13 PF13166.6 OAJ08189.1 - 5.8 5.4 29.2 0.98 8.0 19.1 2.7 2 1 1 3 3 3 0 AAA domain HOOK PF05622.12 OAJ08189.1 - 6.2 4.8 35.5 0.85 7.7 0.2 2.5 2 1 0 2 2 2 0 HOOK protein TPR_MLP1_2 PF07926.12 OAJ08189.1 - 6.6 6.8 45.5 1 9.4 0.7 4.0 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 OAJ08189.1 - 7.5 6.7 18.9 31 4.7 0.1 4.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family CCDC92 PF14916.6 OAJ08189.1 - 9.1 6.1 11.6 16 5.3 0.5 3.7 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Pyr_redox_2 PF07992.14 OAJ08191.1 - 1.4e-64 218.2 0.8 2.1e-64 217.6 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAJ08191.1 - 1.5e-32 112.2 2.2 1.9e-32 111.8 1.4 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAJ08191.1 - 2.3e-19 69.7 4.6 2.7e-17 63.1 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ08191.1 - 8.2e-12 45.0 0.1 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ08191.1 - 1.3e-06 27.4 1.6 0.016 13.9 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 OAJ08191.1 - 1.9e-05 24.3 0.2 6e-05 22.6 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ08191.1 - 0.0016 17.6 0.0 0.0063 15.7 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ08191.1 - 0.007 16.6 0.7 0.025 14.8 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ08191.1 - 0.011 14.9 1.0 0.073 12.1 0.5 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAJ08191.1 - 0.012 15.6 0.2 4.1 7.4 0.0 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 OAJ08191.1 - 0.029 14.2 0.7 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAJ08191.1 - 0.048 12.9 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ08191.1 - 0.097 11.7 0.1 0.57 9.2 0.5 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 OAJ08191.1 - 2.3 7.7 5.6 31 4.0 5.6 2.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Snapin_Pallidin PF14712.6 OAJ08196.1 - 0.026 15.0 0.3 0.034 14.6 0.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Dimerisation PF08100.11 OAJ08196.1 - 0.061 13.4 0.2 24 5.1 0.0 2.9 1 1 2 3 3 3 0 Dimerisation domain UQ_con PF00179.26 OAJ08199.1 - 1.3e-14 54.1 0.1 1.8e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ08199.1 - 0.1 12.5 0.2 0.23 11.3 0.2 1.6 1 1 0 1 1 1 0 UEV domain UPF0029 PF01205.19 OAJ08200.1 - 6.9e-19 68.1 0.0 2.1e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF4407 PF14362.6 OAJ08200.1 - 0.053 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Con-6 PF10346.9 OAJ08201.1 - 4.7e-09 36.1 0.3 1e-08 35.1 0.3 1.5 1 0 0 1 1 1 1 Conidiation protein 6 RNase_T PF00929.24 OAJ08203.1 - 2.2e-08 34.8 0.0 5.9e-07 30.2 0.0 2.8 3 0 0 3 3 3 1 Exonuclease MBOAT PF03062.19 OAJ08204.1 - 3.8e-47 161.3 1.5 3.9e-46 158.0 1.5 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RskA PF10099.9 OAJ08204.1 - 0.26 11.6 4.8 5.9 7.2 0.7 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA HA2 PF04408.23 OAJ08209.1 - 3.3e-18 65.9 1.0 1.8e-17 63.6 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAJ08209.1 - 1.7e-15 57.3 0.1 4.3e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAJ08209.1 - 7.1e-11 42.3 0.1 1.5e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OAJ08209.1 - 7.2e-07 29.6 0.2 4.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAJ08209.1 - 0.051 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 OAJ08209.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 OAJ08209.1 - 0.45 11.0 1.3 1 9.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF3035 PF11233.8 OAJ08209.1 - 3.5 7.9 14.9 0.042 14.1 5.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Fer2 PF00111.27 OAJ08210.1 - 2.9e-12 46.4 0.3 3.8e-12 46.0 0.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain UCMA PF17085.5 OAJ08211.1 - 0.034 14.2 5.8 0.084 12.9 5.8 1.7 1 0 0 1 1 1 0 Unique cartilage matrix associated protein SPT2 PF08243.11 OAJ08211.1 - 0.89 10.1 27.6 0.055 14.0 20.5 2.3 1 1 1 2 2 2 0 SPT2 chromatin protein TFIIA PF03153.13 OAJ08211.1 - 1.7 8.6 17.0 2 8.3 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.13 OAJ08211.1 - 3.2 7.4 18.4 4.3 7.0 18.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 OAJ08211.1 - 7.5 4.7 19.6 12 4.1 19.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SOAR PF16533.5 OAJ08212.1 - 0.13 12.2 0.4 0.23 11.5 0.4 1.4 1 0 0 1 1 1 0 STIM1 Orai1-activating region FYVE PF01363.21 OAJ08213.1 - 3.4e-15 55.9 8.9 4.4e-15 55.6 8.9 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OAJ08213.1 - 0.029 14.6 7.6 0.071 13.3 7.6 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 OAJ08213.1 - 0.71 10.1 9.3 0.16 12.1 2.2 2.4 3 0 0 3 3 3 0 B-box zinc finger HypA PF01155.19 OAJ08213.1 - 2 8.5 7.3 1.9 8.5 2.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_11 PF17123.5 OAJ08214.1 - 7e-05 22.5 0.9 0.00015 21.5 0.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAJ08214.1 - 0.0082 16.5 0.2 0.016 15.5 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain Hist_deacetyl PF00850.19 OAJ08218.1 - 7.5e-83 278.5 0.0 1.2e-82 277.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 OAJ08218.1 - 4.2e-09 35.9 0.0 0.00021 20.5 0.0 3.3 3 0 0 3 3 3 2 Arb2 domain HTH_IclR PF09339.10 OAJ08218.1 - 0.08 12.8 0.2 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain V_ATPase_I PF01496.19 OAJ08222.1 - 0 1029.1 0.0 0 1028.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 OAJ08222.1 - 0.04 14.3 0.7 0.11 12.9 0.7 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 OAJ08222.1 - 0.1 12.2 1.1 0.18 11.4 1.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TSNAXIP1_N PF15739.5 OAJ08222.1 - 0.12 12.8 0.4 24 5.4 0.3 2.5 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Prefoldin_2 PF01920.20 OAJ08222.1 - 0.25 11.3 3.8 0.11 12.4 0.5 2.1 3 0 0 3 3 3 0 Prefoldin subunit GAS PF13851.6 OAJ08222.1 - 0.26 10.6 3.5 1.3 8.4 2.5 2.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FTA4 PF13093.6 OAJ08222.1 - 0.91 9.4 6.8 3.8 7.3 4.9 2.2 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DEAD PF00270.29 OAJ08223.1 - 4e-30 104.9 0.0 1.2e-29 103.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ08223.1 - 8.4e-29 100.2 0.0 2.4e-27 95.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ08223.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ08223.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Na_H_Exchanger PF00999.21 OAJ08228.1 - 1.3e-56 192.0 49.3 2e-56 191.4 49.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 OAJ08233.1 - 7.4e-72 241.9 0.0 9.9e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08233.1 - 1e-28 100.4 0.0 1.2e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ08233.1 - 5.7e-08 32.4 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ08233.1 - 3.4e-05 22.8 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ08233.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NtA PF03146.15 OAJ08233.1 - 0.039 13.8 0.1 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Agrin NtA domain APH PF01636.23 OAJ08233.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.27 OAJ08235.1 - 9.6e-25 87.4 0.0 1.7e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08235.1 - 7.2e-15 54.8 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ08235.1 - 1.5e-14 53.9 0.0 3.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08235.1 - 1.5e-11 44.5 0.0 3.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08235.1 - 0.00017 22.2 0.3 0.00048 20.7 0.1 1.9 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.17 OAJ08235.1 - 0.0028 17.9 0.2 0.0063 16.8 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 OAJ08235.1 - 0.0031 17.8 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ08235.1 - 0.016 15.7 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ08235.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease PTPRCAP PF15713.5 OAJ08240.1 - 0.00041 20.7 5.7 0.00087 19.6 5.7 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 OAJ08240.1 - 0.00083 17.8 6.5 0.0011 17.4 6.5 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 OAJ08240.1 - 0.0012 19.0 10.1 0.002 18.3 10.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 OAJ08240.1 - 0.01 14.1 10.2 0.013 13.8 10.2 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAJ08240.1 - 0.013 14.9 11.4 0.019 14.4 11.4 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 OAJ08240.1 - 0.031 12.4 15.1 0.043 11.9 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAJ08240.1 - 0.033 13.9 8.9 0.059 13.1 8.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.13 OAJ08240.1 - 0.26 10.9 8.1 0.45 10.1 8.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM176 PF14851.6 OAJ08240.1 - 0.93 9.1 8.4 1.7 8.3 8.4 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 OAJ08240.1 - 1.5 8.8 7.1 2.8 7.9 7.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TLP-20 PF06088.11 OAJ08240.1 - 2 8.3 5.9 4.6 7.1 5.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4637 PF15470.6 OAJ08240.1 - 4.5 7.0 11.4 11 5.7 11.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PPV_E1_N PF00524.18 OAJ08240.1 - 5.9 7.3 14.4 9.5 6.7 11.6 2.4 2 1 0 2 2 2 0 E1 Protein, N terminal domain RRN3 PF05327.11 OAJ08240.1 - 9.8 4.6 9.0 14 4.1 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1308 PF07000.11 OAJ08244.1 - 0.00047 20.1 0.1 0.045 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) Pkinase PF00069.25 OAJ08245.1 - 4.9e-05 22.8 0.0 0.0001 21.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08245.1 - 0.17 11.1 0.0 0.65 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Tup_N PF08581.10 OAJ08247.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 Tup N-terminal ADIP PF11559.8 OAJ08247.1 - 0.18 11.9 2.5 9.3 6.3 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding UBM PF14377.6 OAJ08248.1 - 4.6 6.8 8.7 1.2 8.7 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin binding region UPF0020 PF01170.18 OAJ08249.1 - 0.0082 15.8 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 OAJ08249.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ08249.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SurE PF01975.17 OAJ08257.1 - 8.6e-33 113.8 2.3 1.4e-32 113.0 0.1 2.1 1 1 1 2 2 2 1 Survival protein SurE ABC2_membrane PF01061.24 OAJ08258.1 - 1.1e-53 181.8 40.0 5.1e-39 133.9 20.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 OAJ08258.1 - 8.8e-25 86.4 0.0 4.3e-21 74.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 OAJ08258.1 - 7.5e-18 65.4 0.0 1.1e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ08258.1 - 8.8e-06 25.7 0.0 0.082 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAJ08258.1 - 7.8e-05 21.9 27.0 0.0027 16.9 2.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 OAJ08258.1 - 0.00014 21.4 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 OAJ08258.1 - 0.0011 19.1 0.3 0.05 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAJ08258.1 - 0.0014 18.2 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ08258.1 - 0.0023 18.5 0.2 0.017 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ08258.1 - 0.0035 17.3 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OAJ08258.1 - 0.005 16.6 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 OAJ08258.1 - 0.034 13.7 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAJ08258.1 - 0.039 14.3 0.2 0.086 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OAJ08258.1 - 0.066 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ08258.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Dpoe2NT PF12213.8 OAJ08258.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal AAA_22 PF13401.6 OAJ08258.1 - 0.21 11.9 0.0 0.53 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Voltage_CLC PF00654.20 OAJ08262.1 - 2.2e-89 300.2 29.1 2.2e-89 300.2 29.1 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAJ08262.1 - 0.061 13.8 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 CBS domain GP11 PF08677.10 OAJ08262.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 GP11 baseplate wedge protein Histone PF00125.24 OAJ08265.1 - 2.5e-43 147.6 3.6 9.1e-43 145.8 3.6 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ08265.1 - 2.7e-05 24.5 0.0 4.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ08265.1 - 4.3e-05 23.6 0.1 6.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ08265.1 - 0.0081 16.4 0.2 0.013 15.7 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OAJ08265.1 - 0.16 12.5 1.9 0.23 12.1 1.9 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain DUF4840 PF16128.5 OAJ08265.1 - 0.17 11.9 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) Sirohm_synth_M PF14824.6 OAJ08265.1 - 0.21 11.1 1.1 2.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DUF5022 PF16425.5 OAJ08267.1 - 0.22 10.9 0.1 3.5 7.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5022) HEAT_PBS PF03130.16 OAJ08267.1 - 0.34 11.7 2.2 6.5 7.7 0.1 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat K_channel_TID PF07941.11 OAJ08267.1 - 1.2 9.6 17.5 0.17 12.4 1.2 3.2 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.25 OAJ08268.1 - 4.9e-63 213.0 0.0 5.7e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08268.1 - 2.8e-38 131.7 0.0 3.6e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ08268.1 - 1.1e-10 41.3 0.0 2.9e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAJ08268.1 - 0.004 16.5 0.0 0.009 15.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ08268.1 - 0.0043 16.1 0.0 0.0082 15.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ08268.1 - 0.031 14.2 1.0 0.13 12.2 1.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Zip PF02535.22 OAJ08273.1 - 1.4e-59 202.0 8.5 1.6e-59 201.8 8.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter YchF-GTPase_C PF06071.13 OAJ08274.1 - 2.6e-34 117.3 0.1 9.5e-34 115.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAJ08274.1 - 7.7e-17 61.4 0.0 1.6e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ08274.1 - 7.9e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Glyco_transf_20 PF00982.21 OAJ08278.1 - 2.7e-54 184.6 0.0 1.4e-46 159.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 SARAF PF06682.12 OAJ08278.1 - 0.047 13.3 0.6 0.068 12.8 0.6 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Serglycin PF04360.12 OAJ08278.1 - 0.28 11.1 10.1 0.058 13.3 4.5 2.2 2 0 0 2 2 2 0 Serglycin DUF677 PF05055.12 OAJ08279.1 - 0.074 11.9 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_tran_28_C PF04101.16 OAJ08281.1 - 6.5e-16 58.8 0.0 7.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Hydantoinase_A PF01968.18 OAJ08282.1 - 3.5e-75 253.0 0.5 5.2e-75 252.4 0.2 1.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF3053 PF11254.8 OAJ08283.1 - 0.041 13.5 0.2 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) TPR_10 PF13374.6 OAJ08290.1 - 3.5e-17 61.7 23.4 0.0011 18.7 0.4 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ08290.1 - 5.6e-14 52.2 26.2 2e-05 24.8 1.6 6.3 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ08290.1 - 5e-05 23.8 18.7 15 6.7 0.2 8.0 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08290.1 - 0.00013 21.9 17.0 16 5.9 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat FAT PF02259.23 OAJ08290.1 - 0.028 13.6 5.9 2 7.5 1.5 2.7 1 1 0 2 2 2 0 FAT domain MOLO1 PF17175.4 OAJ08290.1 - 0.19 11.9 0.1 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 ANAPC5 PF12862.7 OAJ08290.1 - 0.53 10.4 11.3 3.4 7.8 1.6 5.4 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 OAJ08290.1 - 0.58 11.0 12.6 12 6.9 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 OAJ08290.1 - 0.83 9.8 15.8 1.8 8.8 1.4 4.0 2 2 1 4 4 4 0 PEP-utilising enzyme, N-terminal T2SSF PF00482.23 OAJ08290.1 - 0.87 9.6 7.7 31 4.6 1.5 3.8 1 1 0 3 3 3 0 Type II secretion system (T2SS), protein F SPOR PF05036.13 OAJ08290.1 - 1.5 9.2 5.0 0.91 10.0 0.3 3.0 3 0 0 3 3 3 0 Sporulation related domain BTAD PF03704.17 OAJ08290.1 - 2.4 8.6 18.0 1.7 9.1 0.7 5.4 3 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 OAJ08290.1 - 5 7.4 7.9 11 6.3 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PQ-loop PF04193.14 OAJ08291.1 - 7.7e-26 89.6 11.5 2.8e-15 55.8 1.2 2.9 3 0 0 3 3 3 2 PQ loop repeat Nebulin PF00880.18 OAJ08292.1 - 0.087 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Nebulin repeat Prp19 PF08606.11 OAJ08298.1 - 0.05 13.6 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like Pkinase PF00069.25 OAJ08299.1 - 7.3e-17 61.6 0.0 9.7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08299.1 - 5.2e-11 42.3 0.0 7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ08299.1 - 0.00026 20.4 0.1 0.00036 20.0 0.1 1.1 1 0 0 1 1 1 1 Kinase-like MULE PF10551.9 OAJ08302.1 - 5.6e-13 49.1 0.2 5.2e-08 33.2 0.1 2.6 1 1 1 2 2 2 2 MULE transposase domain Ribosomal_60s PF00428.19 OAJ08302.1 - 0.26 11.9 8.1 4.8 7.8 5.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein E7 PF00527.18 OAJ08302.1 - 2.3 8.5 5.2 42 4.4 0.7 3.0 3 0 0 3 3 3 0 E7 protein, Early protein TPR_12 PF13424.6 OAJ08306.1 - 0.04 14.2 26.3 1.2 9.5 0.2 7.9 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ08306.1 - 0.23 12.2 3.4 12 6.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08306.1 - 0.77 10.0 13.6 9 6.7 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ08306.1 - 5.4 7.0 18.4 3.6 7.6 0.2 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat AMP-binding PF00501.28 OAJ08314.1 - 1.2e-82 277.8 0.0 1.4e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ08314.1 - 8.9e-14 52.2 0.5 1.8e-13 51.3 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain cwf21 PF08312.12 OAJ08315.1 - 1.6e-15 56.9 5.3 1.6e-15 56.9 5.3 2.6 2 1 0 2 2 2 1 cwf21 domain FGGY_C PF02782.16 OAJ08319.1 - 1.1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.16 OAJ08320.1 - 3e-32 111.9 64.0 7e-24 84.4 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1028 PF06267.12 OAJ08321.1 - 0.059 13.1 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF1028) Aminotran_5 PF00266.19 OAJ08322.1 - 2.2e-31 109.1 0.0 4.5e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ08322.1 - 0.00021 20.6 0.0 0.0038 16.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAJ08322.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family EamA PF00892.20 OAJ08323.1 - 4.8e-32 111.0 48.3 9.3e-17 61.5 18.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family RT_RNaseH_2 PF17919.1 OAJ08326.1 - 1.2e-23 83.0 1.3 4.1e-15 55.6 0.1 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08326.1 - 1e-21 77.5 0.0 2.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ08326.1 - 1e-16 61.1 0.0 9e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08326.1 - 1.5e-16 60.2 0.1 2.8e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08326.1 - 2.7e-09 37.2 0.0 6.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08326.1 - 8e-05 23.2 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ08326.1 - 0.026 14.7 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 OAJ08326.1 - 0.03 14.9 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TFIIS_M PF07500.14 OAJ08328.1 - 6.1e-23 81.4 0.3 6.1e-23 81.4 0.3 2.3 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAJ08328.1 - 1.9e-18 66.0 7.7 3.3e-18 65.2 7.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAJ08328.1 - 2.5e-12 46.6 1.0 2.5e-12 46.6 1.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TF_Zn_Ribbon PF08271.12 OAJ08328.1 - 0.089 12.3 0.4 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-DNL PF05180.12 OAJ08328.1 - 0.27 11.2 2.1 0.53 10.3 2.1 1.4 1 0 0 1 1 1 0 DNL zinc finger AMP-binding PF00501.28 OAJ08329.1 - 2.1e-71 240.7 0.0 2.6e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ08329.1 - 2.9e-11 44.2 0.1 7.6e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coatomer_E PF04733.14 OAJ08332.1 - 7.3e-44 150.3 8.2 9.2e-44 150.0 8.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_17 PF13431.6 OAJ08332.1 - 0.035 14.5 0.3 9 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ08332.1 - 0.54 10.8 24.4 1 9.9 4.4 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08332.1 - 1.1 9.5 0.1 1.1 9.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ08332.1 - 2.7 9.1 20.2 3.5 8.7 2.1 5.7 3 2 2 6 6 6 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.22 OAJ08333.1 - 1.2e-150 502.6 0.0 1.7e-150 502.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ08333.1 - 8.6e-21 74.5 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ08333.1 - 4.1e-18 65.3 0.4 6.8e-10 38.2 0.0 4.1 4 0 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAJ08333.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAJ08333.1 - 0.017 14.5 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 OAJ08337.1 - 2e-43 148.7 0.0 5.1e-41 140.8 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08337.1 - 3e-26 92.3 0.0 9.6e-26 90.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ08337.1 - 0.0003 20.8 0.0 0.0003 20.8 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ08337.1 - 0.22 10.3 4.7 0.57 8.9 0.0 2.4 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 OAJ08337.1 - 0.36 10.8 38.3 0.0075 16.3 30.5 2.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF1682 PF07946.14 OAJ08337.1 - 3.5 6.8 10.9 5.8 6.0 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) XRN_M PF17846.1 OAJ08337.1 - 4.7 6.1 9.9 8.1 5.3 9.9 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF4690 PF15756.5 OAJ08341.1 - 0.0065 17.0 0.1 0.012 16.1 0.1 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Corona_M PF01635.18 OAJ08342.1 - 0.37 10.1 5.3 0.66 9.3 5.3 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein KAAG1 PF15354.6 OAJ08342.1 - 4.5 7.9 5.2 10 6.7 0.4 2.6 1 1 1 2 2 2 0 Kidney-associated antigen 1 DUF866 PF05907.13 OAJ08347.1 - 4.9e-48 162.9 0.6 5.6e-48 162.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1272 PF06906.11 OAJ08347.1 - 0.052 13.6 2.1 0.23 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) OPT PF03169.15 OAJ08353.1 - 1.5e-154 516.0 51.2 1.9e-154 515.7 51.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FYDLN_acid PF09538.10 OAJ08353.1 - 8.7 7.1 11.8 15 6.3 5.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FUN14 PF04930.15 OAJ08358.1 - 4.8e-20 71.8 1.7 9.2e-20 70.9 1.7 1.5 1 0 0 1 1 1 1 FUN14 family Actin PF00022.19 OAJ08359.1 - 4.4e-91 305.5 0.0 2.6e-90 302.9 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 OAJ08359.1 - 0.0092 14.6 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase GerD PF17898.1 OAJ08359.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain p450 PF00067.22 OAJ08360.1 - 2.8e-72 243.9 0.0 3.7e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 OAJ08363.1 - 3.3e-38 131.2 0.0 1.2e-37 129.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ08363.1 - 2.6e-18 66.4 0.0 7.4e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ08363.1 - 3.2e-14 52.9 0.0 6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ08363.1 - 1.5e-06 28.3 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 OAJ08363.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.6 OAJ08363.1 - 0.035 14.4 0.0 0.34 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CSRNP_N PF16019.5 OAJ08363.1 - 0.41 10.5 6.8 0.74 9.7 6.8 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CCDC106 PF15794.5 OAJ08363.1 - 1 9.1 15.1 2 8.1 15.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MFMR_assoc PF16596.5 OAJ08363.1 - 2.1 8.8 8.2 0.56 10.7 4.3 2.1 2 0 0 2 2 2 0 Disordered region downstream of MFMR CDC45 PF02724.14 OAJ08363.1 - 7.6 4.7 14.4 12 4.0 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Tombus_P33 PF08500.10 OAJ08363.1 - 7.6 6.5 7.3 17 5.4 6.7 1.8 1 1 0 1 1 1 0 Tombusvirus p33 Antifungal_pept PF11410.8 OAJ08364.1 - 1.3 9.0 7.5 0.37 10.7 1.6 2.6 2 2 0 2 2 2 0 Antifungal peptide SSP160 PF06933.11 OAJ08364.1 - 4.2 5.4 17.6 4.9 5.2 17.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 OAJ08364.1 - 6.3 4.6 6.8 6 4.7 6.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 OAJ08364.1 - 7 4.7 7.6 6.8 4.7 7.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RAP1 PF07218.11 OAJ08365.1 - 0.0031 15.9 13.9 0.0034 15.7 13.9 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 OAJ08365.1 - 1.6 7.5 16.2 1.7 7.4 16.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 OAJ08365.1 - 5.8 5.4 19.1 5.5 5.5 19.1 1.1 1 0 0 1 1 1 0 Hamartin protein CytochromB561_N PF09786.9 OAJ08365.1 - 9.8 5.0 20.8 12 4.8 20.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal RVT_1 PF00078.27 OAJ08367.1 - 1.6e-23 83.4 0.0 2.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08367.1 - 3.2e-19 68.8 0.0 4.6e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08367.1 - 6.5e-16 58.5 0.0 1.5e-10 41.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08367.1 - 2.2e-14 53.3 0.0 4.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08367.1 - 2.1e-12 47.3 0.0 4.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08367.1 - 0.17 12.2 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger NDC10_II PF16787.5 OAJ08370.1 - 1.6e-57 195.0 0.1 4.2e-57 193.6 0.0 1.6 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 EIF4E-T PF10477.9 OAJ08370.1 - 0.011 14.6 14.8 0.016 14.0 14.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E ABC2_membrane_3 PF12698.7 OAJ08370.1 - 0.018 14.2 4.0 0.029 13.5 4.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein FAM199X PF15814.5 OAJ08370.1 - 1.3 8.0 6.9 2.1 7.3 6.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Suf PF05843.14 OAJ08370.1 - 1.9 8.4 12.8 3.4 7.6 12.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 OAJ08370.1 - 2.7 6.6 5.6 4.2 6.0 5.6 1.3 1 0 0 1 1 1 0 Presenilin Na_H_Exchanger PF00999.21 OAJ08374.1 - 0.006 15.4 1.2 0.0082 15.0 1.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MannoseP_isomer PF01050.18 OAJ08384.1 - 5.9e-07 29.5 0.1 7.5e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Dus PF01207.17 OAJ08385.1 - 2.8e-62 210.6 0.0 2.2e-53 181.4 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TPR_1 PF00515.28 OAJ08385.1 - 2.7e-05 23.8 3.6 1.8 8.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ08385.1 - 0.0013 19.3 2.4 2.5 8.8 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ08385.1 - 0.0019 17.8 0.0 0.071 12.8 0.1 2.7 2 0 0 2 2 2 1 TPR repeat NMO PF03060.15 OAJ08385.1 - 0.012 15.0 0.0 0.071 12.5 0.0 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase TPR_2 PF07719.17 OAJ08385.1 - 0.016 15.3 5.8 1.1 9.6 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-Q PF13094.6 OAJ08385.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.6 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit RVT_2 PF07727.14 OAJ08391.1 - 3.1e-68 230.0 0.0 4.4e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08391.1 - 1.3e-15 57.6 0.0 2e-14 53.8 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08391.1 - 3.1e-05 23.8 0.0 7.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3425 PF11905.8 OAJ08391.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Retrotran_gag_2 PF14223.6 OAJ08392.1 - 1.9e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ08392.1 - 0.11 12.6 2.9 0.21 11.8 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ08392.1 - 0.74 9.6 4.6 1.6 8.5 4.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C2H2 PF00096.26 OAJ08394.1 - 0.0016 18.8 2.4 0.0016 18.8 2.4 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ08394.1 - 0.023 15.1 1.9 0.023 15.1 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ08394.1 - 0.027 15.3 2.1 0.027 15.3 2.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger IF-2B PF01008.17 OAJ08397.1 - 1.1e-66 224.9 0.0 1.5e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family MmgE_PrpD PF03972.14 OAJ08398.1 - 5.2e-74 249.3 0.4 2.5e-41 141.6 0.1 2.0 1 1 1 2 2 2 2 MmgE/PrpD family MmgE_PrpD PF03972.14 OAJ08399.1 - 3.4e-10 39.1 0.0 3.8e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RVT_2 PF07727.14 OAJ08404.1 - 1.3e-69 234.5 0.0 2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08404.1 - 2.9e-18 66.2 0.0 7.4e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ08404.1 - 9.8e-06 25.3 0.1 2.8e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08404.1 - 0.00087 19.1 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ08405.1 - 3e-05 23.9 5.1 6.8e-05 22.8 5.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ08405.1 - 0.011 15.6 5.3 0.02 14.7 5.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ08405.1 - 0.039 13.9 1.5 0.074 13.0 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF455 PF04305.14 OAJ08408.1 - 7.5e-93 310.6 0.0 9.8e-93 310.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 OAJ08408.1 - 3.2e-08 33.4 0.8 1.2e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OAJ08408.1 - 0.0019 18.1 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Amidase PF01425.21 OAJ08409.1 - 3.9e-93 312.9 0.0 9.7e-93 311.6 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF4449 PF14613.6 OAJ08413.1 - 2.2e-34 118.9 1.4 2.2e-34 118.9 1.4 3.5 3 1 0 4 4 4 1 Protein of unknown function (DUF4449) Endotoxin_N PF03945.14 OAJ08413.1 - 0.04 13.6 2.2 0.051 13.3 0.5 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain pPIWI_RE_Z PF18155.1 OAJ08413.1 - 0.12 12.2 0.3 0.37 10.6 0.2 1.9 2 0 0 2 2 2 0 pPIWI RE three-gene island domain Z NT-C2 PF10358.9 OAJ08417.1 - 1.5e-11 44.2 0.0 0.0017 18.1 0.0 3.7 3 1 0 3 3 3 3 N-terminal C2 in EEIG1 and EHBP1 proteins NOA36 PF06524.12 OAJ08417.1 - 1.5 8.1 10.8 3.4 6.9 10.8 1.5 1 0 0 1 1 1 0 NOA36 protein CCD PF07860.11 OAJ08417.1 - 5.5 7.0 10.3 4.4 7.4 7.6 2.2 2 0 0 2 2 2 0 WisP family C-Terminal Region MDM31_MDM32 PF08118.11 OAJ08422.1 - 1e-178 595.3 0.0 3.6e-178 593.5 0.0 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins SPX PF03105.19 OAJ08422.1 - 0.018 15.0 2.0 0.027 14.4 2.0 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 OAJ08422.1 - 1.8 7.3 5.5 2.8 6.7 5.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 OAJ08422.1 - 7.9 6.1 19.2 12 5.5 19.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 ATP-sulfurylase PF01747.17 OAJ08430.1 - 2.1e-88 295.3 0.4 3.3e-88 294.7 0.4 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 OAJ08430.1 - 6.5e-54 182.1 0.0 1.1e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAJ08430.1 - 6.2e-51 172.2 0.0 1.1e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 OAJ08430.1 - 0.14 12.3 0.0 0.5 10.5 0.0 1.9 1 1 0 1 1 1 0 Cytidylyltransferase-like Zip PF02535.22 OAJ08431.1 - 5.6 6.1 9.7 10 5.2 9.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 OAJ08431.1 - 7 4.8 15.1 12 4.0 15.1 1.3 1 0 0 1 1 1 0 Smg8_Smg9 GIT_SHD PF08518.11 OAJ08433.1 - 3.6e-24 84.1 8.2 1.2e-13 50.4 1.6 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3584 PF12128.8 OAJ08433.1 - 0.023 12.3 20.6 0.044 11.3 20.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FKBP_C PF00254.28 OAJ08434.1 - 2.5e-34 117.5 0.1 3.4e-33 113.8 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.18 OAJ08434.1 - 1.2e-05 25.3 11.7 1.5e-05 24.9 11.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.10 OAJ08434.1 - 0.0006 20.0 14.8 0.0012 19.1 14.8 1.6 1 0 0 1 1 1 1 Phasin protein ApoLp-III PF07464.11 OAJ08434.1 - 0.0014 18.7 8.1 0.0014 18.7 8.1 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 OAJ08434.1 - 0.027 15.0 19.3 0.32 11.6 8.8 2.8 1 1 1 2 2 2 0 YtxH-like protein DUF3994 PF13159.6 OAJ08434.1 - 0.12 13.0 2.0 8 7.1 1.9 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) DUF883 PF05957.13 OAJ08434.1 - 0.2 12.3 13.9 0.59 10.8 6.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GGDEF PF00990.21 OAJ08434.1 - 0.37 10.5 2.0 0.59 9.9 2.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain HisKA_3 PF07730.13 OAJ08434.1 - 1.3 9.6 4.6 2.7 8.6 0.7 2.8 1 1 1 2 2 2 0 Histidine kinase Borrelia_P83 PF05262.11 OAJ08434.1 - 2.6 6.4 15.6 4.2 5.8 15.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIVA PF05103.13 OAJ08434.1 - 3.8 7.6 18.5 5.5 7.1 7.1 2.2 1 1 1 2 2 2 0 DivIVA protein DUF1508 PF07411.12 OAJ08434.1 - 4.1 7.3 10.2 5.2 7.0 0.8 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1508) ApoO PF09769.9 OAJ08434.1 - 6.5 6.7 6.8 2e+02 2.0 6.7 2.3 1 1 0 1 1 1 0 Apolipoprotein O HK97-gp10_like PF04883.12 OAJ08434.1 - 8.9 7.4 16.4 15 6.7 2.7 3.5 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component RT_RNaseH_2 PF17919.1 OAJ08446.1 - 1.2e-30 105.5 0.0 3e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08446.1 - 1.2e-27 96.3 0.0 2.4e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08446.1 - 7e-20 71.5 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08446.1 - 1.5e-12 47.4 0.0 3.4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 OAJ08446.1 - 0.015 16.0 0.1 0.072 13.7 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease HEAT_EZ PF13513.6 OAJ08449.1 - 1.6e-05 25.2 4.2 0.004 17.6 0.2 2.8 2 2 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 OAJ08449.1 - 0.00056 19.9 4.4 0.028 14.7 0.1 3.8 3 1 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 OAJ08449.1 - 0.0011 19.4 3.2 0.59 10.6 0.4 3.0 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 OAJ08449.1 - 8.3 7.4 7.7 28 5.7 0.6 3.0 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat PAPA-1 PF04795.12 OAJ08454.1 - 3.5e-24 85.4 3.3 3.5e-24 85.4 3.3 3.5 3 3 0 3 3 3 1 PAPA-1-like conserved region Atg14 PF10186.9 OAJ08454.1 - 0.69 8.9 3.6 1 8.4 3.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 OAJ08455.1 - 1.1e-53 179.1 5.9 2e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PUMA PF15826.5 OAJ08455.1 - 0.013 15.7 0.6 0.025 14.8 0.6 1.4 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Dehydrin PF00257.19 OAJ08455.1 - 1.3 9.5 3.9 1.4 9.5 3.1 1.4 1 1 0 1 1 1 0 Dehydrin UvrD_C_2 PF13538.6 OAJ08458.1 - 0.061 13.2 0.4 0.12 12.2 0.4 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain MFS_1 PF07690.16 OAJ08462.1 - 3e-12 46.2 23.5 3.4e-12 46.0 23.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nop53 PF07767.11 OAJ08466.1 - 1.2e-17 64.5 0.5 1.4e-17 64.3 0.5 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CPSase_sm_chain PF00988.22 OAJ08467.1 - 1.4e-43 147.7 0.0 2.4e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OAJ08467.1 - 1.2e-35 123.0 0.0 2.6e-35 121.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAJ08467.1 - 6.5e-06 26.1 0.2 9.5e-05 22.2 0.6 2.3 2 1 0 2 2 2 1 Peptidase C26 CASP_C PF08172.12 OAJ08468.1 - 4.4e-67 226.1 10.1 2e-65 220.7 0.0 4.3 1 1 2 3 3 3 1 CASP C terminal ZapB PF06005.12 OAJ08468.1 - 0.095 13.2 0.1 0.095 13.2 0.1 6.2 5 2 0 5 5 5 0 Cell division protein ZapB KLRAQ PF10205.9 OAJ08468.1 - 0.1 12.8 0.2 0.1 12.8 0.2 5.4 4 1 2 6 6 6 0 Predicted coiled-coil domain-containing protein MPS2 PF17060.5 OAJ08468.1 - 0.29 10.4 10.3 1.3 8.2 8.3 2.6 2 1 0 2 2 2 0 Monopolar spindle protein 2 SOGA PF11365.8 OAJ08468.1 - 0.37 12.0 35.6 0.51 11.5 0.1 6.4 4 2 1 5 5 5 0 Protein SOGA SlyX PF04102.12 OAJ08468.1 - 0.87 10.2 0.0 0.87 10.2 0.0 7.7 6 2 3 9 9 9 0 SlyX CENP-H PF05837.12 OAJ08468.1 - 1.3 9.5 0.0 1.3 9.5 0.0 6.5 4 1 2 6 6 6 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 OAJ08468.1 - 1.7 9.6 0.0 1.7 9.6 0.0 5.9 3 1 3 6 6 6 0 cGMP-dependent protein kinase interacting domain Shugoshin_N PF07558.11 OAJ08468.1 - 2.5 8.0 6.0 8.2 6.4 0.3 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4407 PF14362.6 OAJ08468.1 - 9.3 5.5 45.8 4.4 6.6 2.9 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Phosducin PF02114.16 OAJ08472.1 - 8.1e-09 34.8 0.2 1.9e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Phosducin Cwf_Cwc_15 PF04889.12 OAJ08472.1 - 2 8.1 12.5 0.12 12.1 5.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 OAJ08472.1 - 4 5.4 5.8 4.5 5.2 0.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen GOLD_2 PF13897.6 OAJ08472.1 - 4.6 7.8 5.6 0.49 10.9 0.4 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PBP1_TM PF14812.6 OAJ08472.1 - 8.1 6.9 17.4 0.65 10.4 8.6 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DnaJ PF00226.31 OAJ08473.1 - 0.00021 21.3 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 OAJ08473.1 - 0.0031 17.2 1.1 0.031 14.1 1.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ08473.1 - 0.017 15.4 0.7 0.056 13.7 0.7 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Spt20 PF12090.8 OAJ08473.1 - 0.11 12.1 16.0 0.45 10.1 16.0 2.0 1 0 0 1 1 1 0 Spt20 family TPR_2 PF07719.17 OAJ08473.1 - 0.41 10.9 13.8 0.034 14.3 1.6 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat GATA PF00320.27 OAJ08477.1 - 8.2e-17 60.5 5.1 1.6e-16 59.6 5.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAJ08477.1 - 3.2e-13 49.3 0.9 5.9e-13 48.4 0.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) F-box-like PF12937.7 OAJ08479.1 - 0.00016 21.5 0.6 0.00034 20.4 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ08479.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain UBA2_C PF16195.5 OAJ08479.1 - 1.6 9.5 8.1 4.5 8.0 5.5 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Serine_protease PF18405.1 OAJ08480.1 - 0.062 12.4 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease RT_RNaseH_2 PF17919.1 OAJ08486.1 - 6e-30 103.2 0.0 1.6e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08486.1 - 1.7e-25 89.3 0.1 4.1e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08486.1 - 5.3e-19 68.6 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08486.1 - 2e-12 47.0 0.0 8.9e-12 44.9 0.0 2.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08486.1 - 5e-09 36.4 0.5 1.7e-08 34.6 0.2 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 OAJ08486.1 - 0.016 15.2 2.0 0.016 15.2 2.0 2.0 2 0 0 2 2 2 0 Zinc knuckle Tropomyosin PF00261.20 OAJ08491.1 - 0.0041 16.5 0.7 0.0073 15.7 0.7 1.3 1 0 0 1 1 1 1 Tropomyosin HAMP PF00672.25 OAJ08491.1 - 0.014 15.7 1.4 2.8 8.4 0.0 2.7 2 0 0 2 2 2 0 HAMP domain Cytochrom_B562 PF07361.11 OAJ08491.1 - 0.041 14.5 1.9 0.97 10.1 0.1 2.3 2 0 0 2 2 2 0 Cytochrome b562 Peptidase_S10 PF00450.22 OAJ08492.1 - 4.8e-89 299.7 0.0 1.3e-76 258.7 0.0 2.5 2 1 0 2 2 2 2 Serine carboxypeptidase Ank_2 PF12796.7 OAJ08498.1 - 1.9e-12 47.6 0.1 1.3e-10 41.7 0.2 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ08498.1 - 2.5e-10 39.7 0.3 0.00048 20.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAJ08498.1 - 6.7e-10 39.3 0.1 0.0037 17.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ08498.1 - 1.3e-08 34.9 0.4 9.4e-05 22.6 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ08498.1 - 2e-08 34.3 0.6 0.0013 19.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat SPT16 PF08644.11 OAJ08498.1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) UPF0524 PF15823.5 OAJ08498.1 - 0.073 12.5 0.6 0.14 11.6 0.6 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 Rtf2 PF04641.12 OAJ08498.1 - 1.4 8.2 10.1 0.15 11.4 3.5 2.3 2 1 0 2 2 2 0 Rtf2 RING-finger SQHop_cyclase_C PF13243.6 OAJ08499.1 - 1.7e-47 162.1 2.6 8.3e-46 156.5 0.7 2.5 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OAJ08499.1 - 3.7e-45 154.3 0.0 1.3e-35 122.9 0.0 4.3 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OAJ08499.1 - 1.1e-30 105.0 11.6 1.5e-08 34.2 0.0 7.4 8 0 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAJ08499.1 - 1.2e-06 27.7 0.5 0.005 15.9 0.1 4.1 1 1 2 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 OAJ08499.1 - 0.0028 17.0 0.2 2.6 7.3 0.0 4.0 1 1 0 3 3 3 1 Pectic acid lyase SPT2 PF08243.11 OAJ08500.1 - 0.07 13.7 2.4 0.098 13.2 2.4 1.5 1 1 0 1 1 1 0 SPT2 chromatin protein MHB PF16525.5 OAJ08500.1 - 0.078 13.2 0.2 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 Haemophore, haem-binding STAT_alpha PF01017.20 OAJ08501.1 - 0.014 15.3 1.6 0.018 14.9 1.6 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain FAM92 PF06730.11 OAJ08501.1 - 0.041 13.3 0.3 0.05 13.0 0.3 1.1 1 0 0 1 1 1 0 FAM92 protein CwfJ_C_2 PF04676.14 OAJ08506.1 - 2e-33 115.2 0.2 3.9e-33 114.3 0.2 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 OAJ08506.1 - 2.3e-26 92.1 0.0 3.1e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 WD40 PF00400.32 OAJ08510.1 - 9.1e-12 45.3 5.2 0.00069 20.4 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08510.1 - 0.00076 19.7 0.0 1 9.7 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HNF-1_N PF04814.13 OAJ08511.1 - 1.5 9.4 10.1 0.77 10.3 1.0 2.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus USP7_ICP0_bdg PF12436.8 OAJ08515.1 - 1.6e-81 273.2 0.0 7.1e-81 271.0 0.0 2.1 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAJ08515.1 - 2.9e-63 213.3 3.6 3.2e-62 209.9 0.4 3.0 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAJ08515.1 - 2.1e-50 171.6 0.0 6.7e-50 170.0 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ08515.1 - 1.1e-23 84.4 0.1 4e-23 82.5 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAJ08515.1 - 2.7e-08 33.9 0.0 1.5e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 MATH domain FF PF01846.19 OAJ08517.1 - 6.9e-16 58.2 15.7 2.2e-06 27.7 0.4 5.1 4 1 0 4 4 4 4 FF domain RhoGAP-FF1 PF16512.5 OAJ08517.1 - 0.0043 17.7 0.9 0.25 12.1 0.0 3.6 3 1 0 3 3 3 1 p190-A and -B Rho GAPs FF domain CDC45 PF02724.14 OAJ08517.1 - 1.3 7.3 11.6 1.3 7.2 10.5 1.6 1 1 0 1 1 1 0 CDC45-like protein Oxysterol_BP PF01237.18 OAJ08518.1 - 1.7e-113 379.2 0.0 5.8e-113 377.5 0.0 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 OAJ08518.1 - 4.5e-16 58.9 0.0 8.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ08518.1 - 3e-06 27.7 0.0 6.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PPR_3 PF13812.6 OAJ08523.1 - 0.14 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 OAJ08523.1 - 0.23 11.7 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 PPR repeat family APH PF01636.23 OAJ08524.1 - 8.7e-19 68.4 0.0 1.3e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CLTH PF10607.9 OAJ08528.1 - 1.1e-11 44.8 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAJ08528.1 - 4e-08 33.2 0.3 8.4e-08 32.1 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ08528.1 - 4.7e-05 23.3 0.6 9.4e-05 22.3 0.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAJ08528.1 - 0.00082 19.5 0.4 0.0019 18.3 0.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ08528.1 - 0.0014 18.9 1.3 0.0033 17.7 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ08528.1 - 0.002 18.0 0.6 0.0038 17.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ08528.1 - 0.0025 17.6 1.3 0.0047 16.8 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ08528.1 - 0.0027 17.5 1.8 0.0056 16.5 1.1 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAJ08528.1 - 0.0041 16.9 0.9 0.0087 15.9 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LisH PF08513.11 OAJ08528.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 LisH LMP PF04778.12 OAJ08528.1 - 0.14 12.0 1.1 5.3 6.9 1.8 2.1 2 0 0 2 2 2 0 LMP repeated region Nucleopor_Nup85 PF07575.13 OAJ08537.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin SGP PF17228.2 OAJ08537.1 - 1.1 10.1 12.5 2.6 8.9 12.5 1.6 1 0 0 1 1 1 0 Sulphur globule protein ICAP-1_inte_bdg PF10480.9 OAJ08539.1 - 1.9 8.5 8.5 2.6 8.0 8.5 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein ANAPC4_WD40 PF12894.7 OAJ08544.1 - 0.0064 16.8 0.0 1.5 9.1 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ08544.1 - 0.042 14.7 2.0 46 5.1 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Sec1 PF00995.23 OAJ08546.1 - 7.7e-05 22.1 0.0 9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DTC PF18102.1 OAJ08546.1 - 0.0091 16.1 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 Deltex C-terminal domain ResB PF05140.14 OAJ08547.1 - 0.11 11.2 1.2 0.14 10.8 1.2 1.1 1 0 0 1 1 1 0 ResB-like family UPF0242 PF06785.11 OAJ08547.1 - 2.5 8.2 7.2 5 7.2 7.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mito_carr PF00153.27 OAJ08551.1 - 3.8e-09 36.3 0.7 0.046 13.6 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein FHA PF00498.26 OAJ08552.1 - 0.033 14.5 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 FHA domain Transposase_21 PF02992.14 OAJ08557.1 - 1e-13 51.1 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ08557.1 - 0.00075 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) NOC3p PF07540.11 OAJ08562.1 - 1.1e-25 89.8 0.2 2.9e-24 85.3 0.0 2.9 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 OAJ08562.1 - 2.2e-12 47.3 0.0 2.2e-12 47.3 0.0 3.1 2 1 0 2 2 2 1 CBF/Mak21 family DUF1929 PF09118.11 OAJ08581.1 - 1.3e-20 73.5 0.1 2.4e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 OAJ08581.1 - 2e-20 73.0 0.3 9.1e-13 48.0 0.0 4.2 4 0 0 4 4 4 3 Glyoxal oxidase N-terminus EcsC PF12787.7 OAJ08585.1 - 0.35 10.5 1.5 0.37 10.4 1.0 1.4 1 1 0 1 1 1 0 EcsC protein family Serpentine_r_xa PF03383.15 OAJ08586.1 - 0.054 13.5 2.5 0.09 12.7 0.6 2.1 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa SelK_SelG PF10961.8 OAJ08586.1 - 0.46 11.1 2.3 2.6 8.7 0.2 3.0 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF5543 PF17697.1 OAJ08589.1 - 0.05 13.9 0.2 0.062 13.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5543) Poxvirus_B22R PF04395.12 OAJ08589.1 - 0.17 11.4 0.3 0.26 10.8 0.3 1.6 1 1 0 1 1 1 0 Poxvirus B22R protein Collagen PF01391.18 OAJ08590.1 - 2.8e-23 81.4 80.8 1e+02 2.8 80.8 3.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) WD40 PF00400.32 OAJ08594.1 - 1.5e-18 66.8 3.3 0.00041 21.1 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08594.1 - 0.00023 21.4 0.0 10 6.5 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 OAJ08594.1 - 4.4 7.2 34.8 1.9 8.4 10.4 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fmp27 PF10344.9 OAJ08594.1 - 9.2 4.2 7.1 20 3.1 7.1 1.5 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF1761 PF08570.10 OAJ08603.1 - 0.065 13.5 0.1 0.098 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Ribosomal_S13_N PF08069.12 OAJ08603.1 - 0.084 12.9 0.2 19 5.4 0.1 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Prefoldin PF02996.17 OAJ08604.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit TpcC PF12642.7 OAJ08604.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Pkinase PF00069.25 OAJ08607.1 - 2.7e-43 148.3 0.0 3.6e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08607.1 - 6.3e-27 94.5 0.0 8e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ08607.1 - 2e-06 27.9 0.1 4.4e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ08607.1 - 9.8e-06 25.1 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ08607.1 - 0.061 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Co_AT_N PF12557.8 OAJ08607.1 - 0.13 12.2 2.7 0.31 11.0 2.7 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal PIN_4 PF13638.6 OAJ08610.1 - 7.1e-22 78.1 0.0 2.8e-21 76.2 0.0 2.0 1 1 0 1 1 1 1 PIN domain PcfJ PF14284.6 OAJ08612.1 - 0.087 12.7 0.9 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 PcfJ-like protein KDZ PF18758.1 OAJ08617.1 - 7.7e-30 104.2 0.0 1.8e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Med26 PF08711.11 OAJ08618.1 - 2.5e-07 30.6 0.1 2.5e-07 30.6 0.1 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RVT_1 PF00078.27 OAJ08625.1 - 7.5e-23 81.2 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08625.1 - 4.5e-21 74.7 0.0 3.7e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08625.1 - 2.5e-15 56.6 0.0 1.2e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08625.1 - 7.2e-14 51.6 0.1 1.4e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08625.1 - 7.3e-12 45.5 0.0 2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08625.1 - 0.031 14.5 0.1 0.068 13.4 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Prok-JAB PF14464.6 OAJ08630.1 - 0.09 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PBP1_TM PF14812.6 OAJ08630.1 - 0.23 11.8 2.8 0.27 11.6 0.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C48 PF02902.19 OAJ08631.1 - 3.8e-11 43.2 0.0 6.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HsbA PF12296.8 OAJ08635.1 - 3.3e-17 63.0 7.1 3.3e-17 63.0 7.1 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF4121 PF13497.6 OAJ08639.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) RNase_PH PF01138.21 OAJ08640.1 - 2.8e-11 44.0 0.1 5.3e-11 43.1 0.1 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Abhydrolase_3 PF07859.13 OAJ08643.1 - 2.3e-25 89.7 0.0 4.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ08643.1 - 1.6e-07 31.0 0.1 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ08643.1 - 0.00031 20.6 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ribosomal_60s PF00428.19 OAJ08643.1 - 0.027 15.1 15.8 0.044 14.4 11.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_22 PF03901.17 OAJ08644.1 - 4.9e-27 95.2 9.1 6.1e-27 94.9 9.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Syntaxin-18_N PF10496.9 OAJ08645.1 - 2.7e-07 30.7 0.1 2.7e-07 30.7 0.1 3.0 4 0 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAJ08645.1 - 0.028 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 SNARE domain SUIM_assoc PF16619.5 OAJ08651.1 - 0.072 13.2 0.2 0.072 13.2 0.2 3.4 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 SBF PF01758.16 OAJ08652.1 - 1.8e-43 148.5 14.4 1.8e-43 148.5 14.4 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3390 PF11870.8 OAJ08656.1 - 0.14 12.5 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) RALF PF05498.11 OAJ08658.1 - 0.017 16.1 0.0 0.48 11.4 0.1 2.1 1 1 1 2 2 2 0 Rapid ALkalinization Factor (RALF) EFG_C PF00679.24 OAJ08662.1 - 0.071 13.1 0.0 5.9 7.0 0.0 2.4 1 1 1 2 2 2 0 Elongation factor G C-terminus Rhabdo_ncap PF00945.18 OAJ08663.1 - 0.012 14.5 2.1 0.016 14.1 2.1 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cnd2 PF05786.14 OAJ08663.1 - 0.048 12.3 1.6 0.061 12.0 1.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 TPR_5 PF12688.7 OAJ08663.1 - 0.059 13.6 0.3 0.086 13.1 0.3 1.2 1 0 0 1 1 1 0 Tetratrico peptide repeat Sigma70_ner PF04546.13 OAJ08663.1 - 0.23 11.3 3.4 0.29 11.0 3.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PGA2 PF07543.12 OAJ08663.1 - 0.27 11.2 1.5 0.33 10.9 1.5 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 OAJ08663.1 - 0.36 11.3 12.8 0.12 12.8 9.9 1.6 1 1 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ08663.1 - 0.8 9.0 5.8 1.1 8.5 5.8 1.1 1 0 0 1 1 1 0 NOA36 protein AKAP2_C PF15304.6 OAJ08664.1 - 0.52 9.6 7.6 1.6 8.0 7.6 1.8 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Phage_integrase PF00589.22 OAJ08669.1 - 0.00021 21.1 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUF1670 PF07900.11 OAJ08669.1 - 0.051 12.9 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) RT_RNaseH_2 PF17919.1 OAJ08669.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF3504 PF12012.8 OAJ08669.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) HMGL-like PF00682.19 OAJ08673.1 - 2.4e-73 247.0 0.0 3.3e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OAJ08673.1 - 3.8e-18 65.7 0.1 3.7e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Myco_19_kDa PF05481.12 OAJ08673.1 - 0.035 14.4 0.2 0.069 13.4 0.2 1.5 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen NAGLU PF05089.12 OAJ08677.1 - 0.042 12.8 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Seryl_tRNA_N PF02403.22 OAJ08677.1 - 7.7 6.8 7.3 1.9 8.8 0.1 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DDE_3 PF13358.6 OAJ08678.1 - 5.9e-30 103.9 0.0 9.2e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ08678.1 - 4.1e-06 27.3 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ08678.1 - 3.4e-05 23.4 0.0 0.00011 21.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 OAJ08678.1 - 0.00019 21.5 0.0 0.071 13.3 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 OAJ08678.1 - 0.00099 18.8 0.0 0.06 13.2 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 OAJ08678.1 - 0.0012 19.0 0.0 0.0092 16.2 0.0 2.3 2 0 0 2 2 2 1 Transposase MFS_1 PF07690.16 OAJ08682.1 - 4e-14 52.3 53.5 9.9e-14 51.0 43.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 OAJ08682.1 - 0.14 12.2 0.3 0.53 10.4 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) RVT_1 PF00078.27 OAJ08687.1 - 5.3e-20 71.9 0.0 8.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone_H2A_C PF16211.5 OAJ08692.1 - 1.8e-17 62.8 0.4 3.7e-17 61.7 0.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ08692.1 - 5.1e-13 49.5 0.0 6.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pyridoxal_deC PF00282.19 OAJ08696.1 - 8.1e-30 103.8 0.0 9.6e-28 96.9 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain DUF3291 PF11695.8 OAJ08696.1 - 0.15 11.7 0.0 3 7.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3291) RVT_2 PF07727.14 OAJ08700.1 - 7.9e-20 71.5 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CGGC PF08821.11 OAJ08700.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 CGGC domain DUF3008 PF11450.8 OAJ08701.1 - 0.0078 16.4 0.3 3.6 7.8 0.5 2.6 2 0 0 2 2 2 2 Protein of unknwon function (DUF3008) UreF PF01730.16 OAJ08701.1 - 0.02 15.4 0.2 0.035 14.7 0.2 1.4 1 0 0 1 1 1 0 UreF Dak2 PF02734.17 OAJ08701.1 - 0.055 13.4 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 DAK2 domain SPDY PF03771.16 OAJ08702.1 - 0.035 14.0 1.2 0.42 10.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Asp PF00026.23 OAJ08706.1 - 1e-45 156.6 0.0 2.7e-45 155.1 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ08706.1 - 2e-08 34.7 0.2 0.00076 19.8 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal SHR3_chaperone PF08229.11 OAJ08707.1 - 1.5e-39 134.9 0.0 2e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 Tlr3_TMD PF17968.1 OAJ08707.1 - 2.1 8.6 5.0 7 6.9 0.3 2.9 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain Ras PF00071.22 OAJ08708.1 - 1.4e-15 57.3 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ08708.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF863 PF05904.11 OAJ08709.1 - 1.2 7.4 7.7 1.3 7.3 7.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) FAM199X PF15814.5 OAJ08709.1 - 4.8 6.1 14.9 6.1 5.8 14.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X RRM_1 PF00076.22 OAJ08712.1 - 4.9e-22 77.5 0.0 7.5e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ08712.1 - 0.068 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif HsbA PF12296.8 OAJ08713.1 - 8.2e-17 61.7 16.0 8.2e-17 61.7 16.0 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A MULE PF10551.9 OAJ08715.1 - 1.3e-06 28.7 0.1 4.6e-06 27.0 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ08715.1 - 0.00017 21.2 1.1 0.00052 19.6 1.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger UCR_6-4kD PF08997.10 OAJ08715.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HbrB PF08539.11 OAJ08720.1 - 3.6e-27 95.4 0.0 3.6e-27 95.4 0.0 4.3 3 1 0 3 3 3 1 HbrB-like Spt20 PF12090.8 OAJ08720.1 - 0.26 10.9 11.6 1.6 8.3 0.2 2.5 2 0 0 2 2 2 0 Spt20 family Folliculin PF11704.8 OAJ08720.1 - 2 8.2 6.7 1.7 8.5 0.1 2.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Zip PF02535.22 OAJ08721.1 - 0.18 11.0 4.8 0.24 10.6 1.9 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter SDA1 PF05285.12 OAJ08721.1 - 2.6 7.4 19.5 0.11 11.9 5.4 2.5 3 0 0 3 3 3 0 SDA1 Sigma70_ner PF04546.13 OAJ08721.1 - 4.8 7.0 11.5 0.27 11.1 4.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Shadoo PF14999.6 OAJ08724.1 - 0.0099 16.0 0.2 0.095 12.8 0.0 2.3 1 1 1 2 2 2 1 Shadow of prion protein, neuroprotective DUF282 PF03380.14 OAJ08724.1 - 1.2 9.1 4.2 8.3 6.4 0.2 2.8 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Chromate_transp PF02417.15 OAJ08727.1 - 6.4e-58 195.4 35.5 1.2e-33 116.5 12.7 2.5 3 0 0 3 3 3 2 Chromate transporter Flavin_Reduct PF01613.18 OAJ08730.1 - 8.4e-32 110.4 0.4 1.2e-31 109.8 0.4 1.3 1 0 0 1 1 1 1 Flavin reductase like domain ADK PF00406.22 OAJ08731.1 - 4.9e-43 146.8 0.0 6.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ08731.1 - 2e-22 80.1 0.0 5.6e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAJ08731.1 - 2.9e-13 49.6 0.0 6.2e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAJ08731.1 - 0.016 15.7 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ08731.1 - 0.023 14.8 0.0 0.055 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain ZnuA PF01297.17 OAJ08731.1 - 0.15 11.4 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic SGT1 PF07093.11 OAJ08732.1 - 3.3e-26 91.9 0.0 3.3e-26 91.9 0.0 4.5 4 1 1 5 5 5 2 SGT1 protein Asp PF00026.23 OAJ08736.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribonuclease_3 PF00636.26 OAJ08737.1 - 1.5e-36 125.2 0.0 1.3e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ08737.1 - 1.8e-18 67.0 0.5 3.6e-10 40.1 0.1 3.6 4 0 0 4 4 4 2 Ribonuclease-III-like DUF4351 PF14261.6 OAJ08737.1 - 0.12 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Integrase_H2C2 PF17921.1 OAJ08739.1 - 9.4e-15 54.5 0.1 1.8e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08739.1 - 1.9e-09 37.8 0.0 4.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08739.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger PAZ PF02170.22 OAJ08739.1 - 0.18 11.6 0.0 24 4.7 0.0 2.2 2 0 0 2 2 2 0 PAZ domain RVT_1 PF00078.27 OAJ08740.1 - 3.3e-05 23.5 0.0 7.1e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mitofilin PF09731.9 OAJ08741.1 - 0.34 9.7 13.5 0.41 9.4 13.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOBP PF15279.6 OAJ08741.1 - 0.71 10.4 13.0 0.96 10.0 13.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.13 OAJ08741.1 - 1 9.2 25.2 1.5 8.7 25.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 OAJ08741.1 - 1.3 7.0 16.7 1.7 6.7 16.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 OAJ08741.1 - 2.3 8.2 6.6 3.5 7.6 6.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.6 OAJ08741.1 - 2.8 6.7 17.9 3.3 6.4 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 OAJ08741.1 - 3.6 6.2 14.6 4.9 5.7 14.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4746 PF15928.5 OAJ08741.1 - 8.3 5.7 7.9 12 5.2 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MCPVI PF02993.14 OAJ08744.1 - 0.043 13.6 5.3 0.064 13.1 5.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI NARP1 PF12569.8 OAJ08744.1 - 0.052 12.5 2.4 0.059 12.3 2.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.12 OAJ08744.1 - 0.073 12.0 3.4 0.086 11.8 3.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 OAJ08744.1 - 0.076 12.6 7.0 0.093 12.3 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EIIBC-GUT_N PF03612.14 OAJ08744.1 - 0.36 10.5 2.4 0.7 9.6 2.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CCDC53 PF10152.9 OAJ08744.1 - 0.41 11.1 6.5 0.62 10.5 6.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 OAJ08744.1 - 0.48 9.1 4.2 0.53 9.0 4.2 1.1 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 OAJ08744.1 - 0.5 10.4 6.0 0.74 9.8 6.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Rrn6 PF10214.9 OAJ08744.1 - 0.8 8.1 15.2 0.99 7.8 15.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Het-C PF07217.11 OAJ08744.1 - 1 7.8 4.2 3.1 6.2 0.0 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Roughex PF06020.11 OAJ08744.1 - 1.4 7.9 6.9 1.8 7.6 6.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 OAJ08744.1 - 1.5 8.3 16.5 2.3 7.8 16.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF3405 PF11885.8 OAJ08744.1 - 1.7 7.1 6.6 2.3 6.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) RR_TM4-6 PF06459.12 OAJ08744.1 - 2 8.2 6.7 3.5 7.4 6.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 OAJ08744.1 - 8.9 4.9 8.9 10 4.6 8.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 OAJ08751.1 - 1.8e-15 56.7 6.7 1.3e-06 27.6 3.2 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAJ08751.1 - 4.3e-07 28.9 3.0 2.3e-06 26.5 0.1 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein PBP1_TM PF14812.6 OAJ08751.1 - 0.021 15.2 7.8 0.033 14.6 1.7 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1_like PF12832.7 OAJ08751.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 MFS_1 like family Plasmodium_Vir PF05795.11 OAJ08751.1 - 0.29 10.5 2.8 0.11 11.8 0.1 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Pox_A12 PF04651.13 OAJ08751.1 - 0.75 9.8 3.4 1.4 9.0 3.4 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Dicty_REP PF05086.12 OAJ08751.1 - 0.99 7.3 1.7 1.6 6.6 1.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4611 PF15387.6 OAJ08751.1 - 2.6 8.3 10.4 1.6 9.0 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 OAJ08751.1 - 3.4 8.1 18.7 2 8.8 11.9 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAJ08751.1 - 6 6.9 6.4 2.5 8.1 2.4 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal ThiF PF00899.21 OAJ08752.1 - 7.5e-34 117.2 0.0 1.8e-33 115.9 0.0 1.5 1 1 0 1 1 1 1 ThiF family TrkA_N PF02254.18 OAJ08752.1 - 0.15 12.4 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Zip PF02535.22 OAJ08752.1 - 1.1 8.4 5.4 0.87 8.7 3.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4148 PF13663.6 OAJ08752.1 - 7.5 6.8 8.7 41 4.5 3.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DDE_Tnp_4 PF13359.6 OAJ08757.1 - 6.9e-07 29.1 0.1 1.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ08757.1 - 1.6e-05 24.6 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_3 PF12776.7 OAJ08758.1 - 8.4e-06 26.7 0.3 2.2e-05 25.3 0.3 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DPPIV_N PF00930.21 OAJ08760.1 - 3.9e-73 246.3 0.0 5.6e-72 242.4 0.0 2.3 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAJ08760.1 - 3.7e-42 144.2 0.5 6.3e-42 143.5 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAJ08760.1 - 0.0012 18.5 0.8 0.0058 16.3 0.6 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAJ08760.1 - 0.028 13.1 0.0 0.073 11.7 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Pal1 PF08316.11 OAJ08769.1 - 2.1e-15 57.7 0.6 4.5e-15 56.6 0.6 1.6 1 1 0 1 1 1 1 Pal1 cell morphology protein PPP4R2 PF09184.11 OAJ08770.1 - 3.4e-11 43.3 0.0 3.4e-11 43.3 0.0 2.7 2 1 0 2 2 2 1 PPP4R2 ANAPC_CDC26 PF10471.9 OAJ08770.1 - 0.0049 17.7 4.0 0.0049 17.7 4.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 Retrotran_gag_2 PF14223.6 OAJ08775.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ08775.1 - 0.00087 19.3 0.6 0.0018 18.3 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ08775.1 - 0.0027 17.5 1.9 0.005 16.6 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.14 OAJ08776.1 - 8.4e-73 245.0 0.0 1.2e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08776.1 - 1.2e-18 67.4 0.0 2.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08776.1 - 2.4e-06 27.3 0.0 5.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ08776.1 - 0.00042 20.0 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SWI2_SNF2 PF18766.1 OAJ08780.1 - 3.8e-73 245.9 0.1 6.6e-73 245.1 0.1 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF45 PF01863.17 OAJ08780.1 - 2.6e-58 197.5 1.8 3.6e-58 197.0 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 HSDR_N PF04313.14 OAJ08780.1 - 2.3e-35 122.3 0.0 1e-34 120.2 0.0 2.2 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 OAJ08780.1 - 2.2e-19 70.1 0.0 4.7e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HATPase_c_4 PF13749.6 OAJ08780.1 - 2.4e-12 46.8 0.0 1e-11 44.8 0.0 2.1 1 0 0 1 1 1 1 Putative ATP-dependent DNA helicase recG C-terminal WLM PF08325.10 OAJ08780.1 - 7.9e-05 22.8 0.1 0.00018 21.6 0.1 1.5 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 OAJ08780.1 - 0.0016 18.3 0.2 0.0048 16.8 0.2 1.8 1 0 0 1 1 1 1 SprT-like family Helo_like_N PF17111.5 OAJ08780.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins RimK PF08443.11 OAJ08780.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain FHA PF00498.26 OAJ08787.1 - 0.17 12.2 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 FHA domain CS PF04969.16 OAJ08792.1 - 1e-06 29.6 0.0 1.9e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 CS domain Serglycin PF04360.12 OAJ08792.1 - 0.0021 18.0 2.1 0.0021 18.0 2.1 3.4 3 0 0 3 3 3 1 Serglycin Cwf_Cwc_15 PF04889.12 OAJ08792.1 - 0.59 9.8 11.3 1.5 8.5 11.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 OAJ08793.1 - 7.7e-39 131.0 22.3 1.8e-06 28.5 0.2 11.3 11 2 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08793.1 - 3.1e-23 81.9 0.1 0.0043 17.3 0.0 8.0 6 3 3 9 9 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ08793.1 - 4.8e-09 35.6 0.4 1.8 7.5 0.0 5.9 4 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ08793.1 - 9e-06 24.6 0.8 1.2 7.7 0.0 5.3 6 0 0 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 OAJ08793.1 - 8.7e-05 22.0 1.1 0.14 11.5 0.0 3.7 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 OAJ08793.1 - 0.00033 20.0 1.3 0.29 10.4 0.0 4.8 4 1 2 6 6 6 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Sporozoite_P67 PF05642.11 OAJ08793.1 - 0.042 11.9 3.2 0.073 11.1 3.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 OAJ08793.1 - 0.96 7.5 4.8 1.3 7.1 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 OAJ08793.1 - 1.4 9.2 5.9 0.33 11.3 2.3 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.11 OAJ08793.1 - 2 8.4 5.8 4.3 7.4 5.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OAJ08793.1 - 7.2 6.3 8.7 1.2 8.8 4.8 1.7 2 0 0 2 2 2 0 FAM176 family AIF_C PF14721.6 OAJ08793.1 - 9.8 6.5 6.3 2.2 8.6 2.2 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PTS_2-RNA PF01885.16 OAJ08797.1 - 1.5e-49 168.5 0.0 2.6e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family GLTP PF08718.11 OAJ08798.1 - 4.3e-49 166.6 0.0 6.2e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ribosomal_L24e PF01246.20 OAJ08799.1 - 3.9e-31 107.1 0.6 3.9e-31 107.1 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e CLTH PF10607.9 OAJ08800.1 - 2.1e-26 92.6 0.0 2.8e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAJ08800.1 - 1.1e-05 25.1 0.6 2.1e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 LisH Ribosomal_60s PF00428.19 OAJ08800.1 - 0.00028 21.4 12.4 0.00062 20.3 12.4 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein LAT PF15234.6 OAJ08800.1 - 0.025 14.3 1.9 0.031 14.0 0.5 1.7 2 0 0 2 2 2 0 Linker for activation of T-cells NOA36 PF06524.12 OAJ08800.1 - 0.99 8.7 6.3 1.4 8.2 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3824 PF12868.7 OAJ08800.1 - 5.2 7.7 6.5 7.9 7.1 6.5 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TMEM220 PF15071.6 OAJ08803.1 - 0.11 13.2 0.3 0.95 10.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF2345 PF10106.9 OAJ08806.1 - 1e-05 25.5 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF2235 PF09994.9 OAJ08808.1 - 2.1e-33 115.9 0.0 1.5e-18 67.1 0.0 2.3 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4123 PF13503.6 OAJ08809.1 - 7.5e-20 71.7 2.5 7.5e-20 71.7 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4123) RNase_H PF00075.24 OAJ08812.1 - 5.6e-11 42.8 0.0 1.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAJ08812.1 - 0.00053 19.8 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like RRN3 PF05327.11 OAJ08819.1 - 2.9e-145 485.0 0.0 1.3e-141 473.0 0.0 2.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 OAJ08819.1 - 0.0034 16.8 14.1 0.0034 16.8 14.1 2.6 2 1 0 2 2 2 1 BUD22 Drc1-Sld2 PF11719.8 OAJ08819.1 - 2.2 7.7 10.7 0.11 12.0 4.2 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein Ribosomal_60s PF00428.19 OAJ08820.1 - 8.5 7.0 6.9 2.5 8.8 2.9 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein RVT_1 PF00078.27 OAJ08824.1 - 1.1e-20 74.2 0.0 1.8e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ApoO PF09769.9 OAJ08829.1 - 2.3e-28 98.8 0.3 4.9e-28 97.7 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF883 PF05957.13 OAJ08829.1 - 0.061 13.9 0.0 3.6 8.2 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3103 PF11301.8 OAJ08829.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) DUF3446 PF11928.8 OAJ08829.1 - 6.5 7.1 9.0 1.4 9.3 4.6 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain HMGL-like PF00682.19 OAJ08830.1 - 1.8e-45 155.6 0.2 2.8e-44 151.6 0.2 2.5 1 1 0 1 1 1 1 HMGL-like ApoO PF09769.9 OAJ08831.1 - 0.00088 19.2 0.4 0.0012 18.8 0.3 1.3 1 1 0 1 1 1 1 Apolipoprotein O Methyltransf_15 PF09445.10 OAJ08844.1 - 2.1e-32 112.0 0.0 1.8e-26 92.7 0.0 2.4 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAJ08844.1 - 1.1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 OAJ08844.1 - 4.2e-06 27.4 0.1 1.1e-05 26.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAJ08844.1 - 0.001 18.8 0.0 0.003 17.2 0.0 1.8 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 OAJ08844.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 OAJ08844.1 - 0.0099 16.5 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ08844.1 - 0.011 15.2 1.9 0.036 13.5 1.9 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 OAJ08844.1 - 0.041 13.5 0.0 0.041 13.5 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical protein 95 TRM PF02005.16 OAJ08844.1 - 0.052 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 OAJ08844.1 - 0.067 12.2 0.0 0.067 12.2 0.0 1.4 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Lin-8 PF03353.15 OAJ08844.1 - 2.2 7.8 14.0 0.15 11.6 8.8 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 OAJ08844.1 - 3 6.8 9.4 4.7 6.1 9.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SelP_N PF04592.14 OAJ08844.1 - 3.9 6.8 16.0 6.9 6.0 16.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SprA-related PF12118.8 OAJ08844.1 - 5.6 6.0 26.3 12 5.0 26.3 1.5 1 0 0 1 1 1 0 SprA-related family NEMP PF10225.9 OAJ08844.1 - 6.7 6.3 4.9 12 5.4 4.9 1.3 1 0 0 1 1 1 0 NEMP family ABC_ATPase PF09818.9 OAJ08847.1 - 2.1e-124 415.7 0.0 2.9e-124 415.3 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class DUF2813 PF11398.8 OAJ08847.1 - 0.05 12.8 0.3 0.85 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_28 PF13521.6 OAJ08847.1 - 0.074 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ08847.1 - 0.17 12.4 1.8 0.91 10.0 1.8 2.1 1 1 0 1 1 1 0 ABC transporter Myb_DNA-binding PF00249.31 OAJ08848.1 - 3.3e-13 49.6 0.1 3.4e-05 23.9 0.0 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ08848.1 - 1.5e-12 47.6 0.0 0.00023 21.3 0.0 4.3 3 1 1 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ08848.1 - 0.022 14.9 0.0 21 5.4 0.0 3.0 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DDE_3 PF13358.6 OAJ08859.1 - 2e-13 50.3 0.2 5.1e-13 49.0 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF4714 PF15833.5 OAJ08860.1 - 0.14 12.1 0.6 0.28 11.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) LapA_dom PF06305.11 OAJ08860.1 - 0.16 11.8 0.8 0.42 10.5 0.8 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HTH_Tnp_Tc3_2 PF01498.18 OAJ08864.1 - 1.6e-12 47.5 1.0 1.5e-10 41.2 0.3 2.3 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 OAJ08864.1 - 7.1e-05 23.3 7.3 0.00063 20.3 0.3 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 OAJ08864.1 - 0.0079 15.6 0.0 0.026 13.9 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 OAJ08864.1 - 0.01 15.6 0.0 0.01 15.6 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 OAJ08864.1 - 0.036 13.8 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 OAJ08864.1 - 0.04 13.9 0.3 0.14 12.2 0.3 2.0 1 1 0 1 1 1 0 Winged helix-turn helix Tox-PL-2 PF15643.6 OAJ08864.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 Sigma54_DBD PF04552.13 OAJ08864.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54, DNA binding domain ABC2_membrane PF01061.24 OAJ08865.1 - 4.1e-25 88.4 11.7 5.5e-25 88.0 11.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ08865.1 - 2e-17 64.0 0.0 2.4e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 ABC transporter ABC_trans_N PF14510.6 OAJ08865.1 - 9.7e-14 51.8 0.3 2.6e-13 50.4 0.3 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal Ter PF05472.11 OAJ08865.1 - 0.042 12.9 0.4 0.067 12.2 0.4 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Vma12 PF11712.8 OAJ08865.1 - 0.19 11.8 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HLH PF00010.26 OAJ08868.1 - 4.6e-10 39.3 0.1 8.8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MCC-bdg_PDZ PF10506.9 OAJ08868.1 - 0.002 18.1 0.7 0.0071 16.3 0.7 2.0 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome GTP_EFTU PF00009.27 OAJ08869.1 - 2.9e-28 98.7 0.6 1.9e-21 76.5 2.0 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ08869.1 - 1.3e-06 28.5 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 OAJ08869.1 - 0.0034 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 OAJ08869.1 - 0.0035 16.8 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TFIIA PF03153.13 OAJ08869.1 - 0.059 13.4 27.4 0.13 12.2 26.8 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FeoB_N PF02421.18 OAJ08869.1 - 0.12 11.8 0.0 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1749 PF08538.10 OAJ08874.1 - 1.4e-06 27.6 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 OAJ08874.1 - 3.8e-06 26.4 0.1 5.5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAJ08874.1 - 0.043 13.3 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.11 OAJ08874.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MARVEL PF01284.23 OAJ08876.1 - 6.3e-12 45.7 9.5 8.4e-12 45.3 9.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MTABC_N PF16185.5 OAJ08876.1 - 3.5 7.1 11.0 0.28 10.6 3.3 2.1 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Snf7 PF03357.21 OAJ08877.1 - 3.9e-31 108.0 16.9 3.9e-31 108.0 16.9 1.4 2 0 0 2 2 2 1 Snf7 LPP PF04728.13 OAJ08877.1 - 0.38 11.2 3.5 2.6 8.5 1.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper LUC7 PF03194.15 OAJ08877.1 - 8.6 5.9 13.3 20 4.7 13.3 1.9 1 1 0 1 1 1 0 LUC7 N_terminus LIM PF00412.22 OAJ08878.1 - 1.4e-32 111.6 24.7 1.2e-13 51.0 3.1 5.3 5 0 0 5 5 5 3 LIM domain SLC12 PF03522.15 OAJ08878.1 - 1.9 7.4 28.3 2.9 6.8 28.3 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Caldesmon PF02029.15 OAJ08878.1 - 2.4 6.8 25.8 3 6.5 25.8 1.1 1 0 0 1 1 1 0 Caldesmon BCDHK_Adom3 PF10436.9 OAJ08882.1 - 5.3e-09 36.1 0.0 8.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase BCDHK_Adom3 PF10436.9 OAJ08884.1 - 1.9e-12 47.3 0.0 2.2e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Flot PF15975.5 OAJ08887.1 - 0.081 13.1 3.5 0.1 12.8 3.5 1.1 1 0 0 1 1 1 0 Flotillin DUF1897 PF09005.10 OAJ08887.1 - 0.24 10.9 2.3 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) FYDLN_acid PF09538.10 OAJ08887.1 - 1.4 9.7 31.2 1.8 9.3 31.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.10 OAJ08887.1 - 1.7 8.9 16.6 1.9 8.8 16.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Serinc PF03348.15 OAJ08887.1 - 4.7 6.0 6.4 5.3 5.8 6.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFB6 PF17110.5 OAJ08887.1 - 5.4 6.7 14.0 6.1 6.6 14.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2796 PF10986.8 OAJ08887.1 - 6.3 6.7 11.5 7.1 6.6 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Cwf_Cwc_15 PF04889.12 OAJ08887.1 - 6.3 6.5 34.2 7.3 6.3 34.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ08887.1 - 9.3 5.5 32.3 12 5.1 32.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4293 PF14126.6 OAJ08896.1 - 0.052 13.8 0.9 0.13 12.5 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) 7tm_7 PF08395.12 OAJ08896.1 - 0.12 11.5 0.7 0.17 11.0 0.7 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF1282 PF06930.12 OAJ08896.1 - 0.17 11.6 6.8 0.24 11.2 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Ni_hydr_CYTB PF01292.20 OAJ08896.1 - 0.26 10.8 6.1 0.43 10.2 5.8 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Phage_integrase PF00589.22 OAJ08900.1 - 9.9e-06 25.4 0.1 3.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family Histone PF00125.24 OAJ08906.1 - 1e-47 161.8 2.1 1.1e-47 161.6 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ08906.1 - 3.2e-05 24.2 0.0 4.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ08906.1 - 9.6e-05 22.5 0.8 0.00012 22.2 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OAJ08906.1 - 0.00082 20.0 2.4 0.001 19.6 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain WD40 PF00400.32 OAJ08907.1 - 3.1e-25 87.9 3.2 2e-06 28.4 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08907.1 - 1.7e-16 60.3 1.8 7.4e-05 23.0 0.1 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ08907.1 - 7.5e-06 26.0 0.1 5.2e-05 23.2 0.1 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Phos_pyr_kin PF08543.12 OAJ08911.1 - 5.2e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAJ08911.1 - 1.2e-05 24.8 0.0 4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DUF4965 PF16335.5 OAJ08912.1 - 1e-66 223.9 0.0 1.9e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAJ08912.1 - 2e-65 220.3 0.3 5.1e-65 219.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 OAJ08912.1 - 6.3e-48 163.5 4.8 1.3e-47 162.5 4.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ08912.1 - 0.0019 17.7 2.6 1.1 8.9 0.2 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ08912.1 - 0.0091 15.5 0.2 0.02 14.4 0.2 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term RVT_1 PF00078.27 OAJ08916.1 - 1.5e-15 57.4 0.0 7.6e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAV_VP3 PF04771.12 OAJ08916.1 - 0.047 13.8 0.2 8.2 6.6 0.1 2.7 2 0 0 2 2 2 0 Chicken anaemia virus VP-3 protein Ribosomal_L37e PF01907.19 OAJ08916.1 - 2.4 8.4 4.6 1.9 8.7 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e Phage_integrase PF00589.22 OAJ08919.1 - 0.16 11.8 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Phage integrase family zf-CCCH_6 PF18585.1 OAJ08926.1 - 2.1 8.3 7.4 7.3 6.6 0.0 3.5 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DDE_1 PF03184.19 OAJ08927.1 - 2.1e-18 66.6 0.0 5.6e-13 48.9 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease cpYpsA PF12694.7 OAJ08927.1 - 0.042 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family AMP-binding PF00501.28 OAJ08931.1 - 3.9e-73 246.5 0.0 2.1e-49 168.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ08931.1 - 5.4e-10 40.1 0.5 1.1e-08 35.9 0.0 3.1 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain UDPGP PF01704.18 OAJ08932.1 - 7.3e-28 97.3 0.0 8.4e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase rve PF00665.26 OAJ08939.1 - 8.6e-10 38.9 0.0 6.8e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08939.1 - 4.4e-07 29.7 0.0 3e-06 27.0 0.0 2.4 2 1 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAJ08939.1 - 0.00081 19.1 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Transcript_VP30 PF11507.8 OAJ08939.1 - 0.037 14.1 0.5 0.079 13.0 0.1 1.7 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 RVT_2 PF07727.14 OAJ08940.1 - 7.8e-68 228.7 0.0 1.2e-67 228.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTCB-BRCT PF12738.7 OAJ08946.1 - 1.6e-29 101.6 3.3 1.7e-18 66.3 0.1 5.4 6 0 0 6 6 6 2 twin BRCT domain BRCT PF00533.26 OAJ08946.1 - 2.9e-28 98.1 0.0 1.2e-12 48.1 0.0 6.7 7 0 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAJ08946.1 - 7.2e-21 74.4 0.0 5.9e-05 23.4 0.0 7.5 6 2 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OAJ08946.1 - 1.4e-12 47.4 0.3 7.4e-11 41.8 0.0 3.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 OAJ08946.1 - 1.8e-06 28.2 0.1 1.6 9.0 0.0 5.1 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain AIM5 PF17050.5 OAJ08946.1 - 0.13 13.1 3.1 1.1 10.2 3.1 2.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 PRIMA1 PF16101.5 OAJ08946.1 - 0.28 11.2 1.5 1 9.4 1.5 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SUIM_assoc PF16619.5 OAJ08946.1 - 0.78 9.8 7.4 0.13 12.3 1.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UPF0183 PF03676.14 OAJ08947.1 - 2.5e-16 60.0 0.1 1.4e-07 31.2 0.3 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) ABC2_membrane PF01061.24 OAJ08953.1 - 1.9e-38 132.0 18.9 1.9e-38 132.0 18.9 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ08953.1 - 9.6e-25 87.7 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ08953.1 - 1.6e-05 24.9 0.1 0.1 12.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAJ08953.1 - 5.7e-05 22.4 23.9 0.00013 21.2 23.9 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.15 OAJ08953.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 OAJ08953.1 - 0.035 14.7 0.0 0.068 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAJ08953.1 - 0.039 13.7 0.9 0.072 12.8 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ08953.1 - 0.094 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAJ08953.1 - 0.14 11.8 0.1 0.33 10.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAJ08953.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ08953.1 - 0.18 11.7 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 OAJ08953.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CENP-F_N PF10481.9 OAJ08953.1 - 0.59 9.7 1.2 0.87 9.2 1.2 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain EamA PF00892.20 OAJ08953.1 - 7.9 6.6 18.5 0.16 12.1 6.2 3.3 3 0 0 3 3 3 0 EamA-like transporter family IlvN PF07991.12 OAJ08959.1 - 1.4e-46 158.1 0.0 2.3e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAJ08959.1 - 3.5e-35 121.4 0.2 6e-35 120.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Oxidored_nitro PF00148.19 OAJ08959.1 - 0.047 12.4 0.0 0.076 11.7 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.17 OAJ08959.1 - 0.065 13.8 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAJ08959.1 - 0.096 12.9 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_4 PF02390.17 OAJ08960.1 - 2.4e-49 167.1 0.0 5.1e-37 127.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase SUIM_assoc PF16619.5 OAJ08960.1 - 0.013 15.6 0.1 0.033 14.3 0.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_12 PF08242.12 OAJ08960.1 - 0.016 15.9 0.0 0.059 14.1 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ08960.1 - 0.027 15.2 0.1 0.26 12.0 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Glycos_transf_2 PF00535.26 OAJ08960.1 - 0.1 12.4 0.0 0.29 10.9 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF913 PF06025.12 OAJ08960.1 - 0.21 10.5 0.4 0.34 9.8 0.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ETF PF01012.21 OAJ08964.1 - 2.5e-42 144.8 3.9 3.5e-42 144.4 3.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF1751 PF08551.10 OAJ08965.1 - 9.4e-26 90.3 7.2 1.7e-25 89.4 7.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OAJ08965.1 - 0.0013 18.7 11.4 0.0029 17.6 11.4 1.6 1 0 0 1 1 1 1 Rhomboid family RT_RNaseH_2 PF17919.1 OAJ08969.1 - 1.9e-29 101.7 0.0 5.2e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08969.1 - 1.6e-25 89.4 0.0 3.3e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08969.1 - 5.1e-20 71.9 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08969.1 - 2.1e-12 47.0 0.0 4.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08969.1 - 2e-08 34.4 0.0 7.2e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ08969.1 - 0.048 13.5 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain DUF4336 PF14234.6 OAJ08969.1 - 0.088 12.0 0.3 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) RFXA_RFXANK_bdg PF15289.6 OAJ08969.1 - 3.2 8.1 8.1 8.9 6.7 5.7 2.7 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain RT_RNaseH_2 PF17919.1 OAJ08973.1 - 7.3e-23 80.5 0.3 7.8e-15 54.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08973.1 - 2e-22 79.8 0.0 3.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ08973.1 - 3.9e-16 59.2 0.0 2.1e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08973.1 - 6.4e-16 58.2 0.2 1.3e-15 57.2 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08973.1 - 2.1e-08 34.3 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Spectrin_like PF18373.1 OAJ08980.1 - 0.14 12.3 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Spectrin like domain RVT_1 PF00078.27 OAJ08981.1 - 1.2e-23 83.8 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08981.1 - 3.7e-13 49.4 0.0 1.1e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ08981.1 - 5.5e-05 23.7 0.0 0.00018 22.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ08981.1 - 0.0078 16.5 0.0 0.048 14.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ08981.1 - 0.02 15.4 0.0 0.068 13.7 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ08981.1 - 0.17 12.2 0.0 0.55 10.6 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease COesterase PF00135.28 OAJ08988.1 - 3.4e-64 217.6 0.0 4.2e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ08988.1 - 3.4e-08 33.6 1.8 5.8e-05 23.1 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold OTU PF02338.19 OAJ08989.1 - 6.5e-09 36.4 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 OAJ08989.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Menin PF05053.13 OAJ08989.1 - 0.31 9.4 0.4 0.44 8.9 0.4 1.1 1 0 0 1 1 1 0 Menin TP2 PF01254.18 OAJ08991.1 - 1 10.0 4.8 2.5 8.7 4.8 1.6 1 0 0 1 1 1 0 Nuclear transition protein 2 RVT_1 PF00078.27 OAJ08992.1 - 4.8e-20 72.0 0.0 8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08992.1 - 7.1e-15 54.9 0.0 2.2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08992.1 - 8.2e-11 42.1 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ08992.1 - 0.016 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase MULE PF10551.9 OAJ08996.1 - 1.9e-23 82.7 0.3 3.7e-23 81.7 0.1 1.5 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ08996.1 - 0.042 12.7 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family DUF1772 PF08592.11 OAJ08997.1 - 3.3 8.0 12.3 0.35 11.2 2.1 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3818 PF12825.7 OAJ08999.1 - 3.7e-128 427.3 0.0 5.6e-128 426.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ08999.1 - 1.1e-39 135.4 0.4 2.2e-39 134.4 0.4 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAJ08999.1 - 4.4e-09 36.3 0.1 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 PX domain Methyltransf_31 PF13847.6 OAJ09000.1 - 5.8e-07 29.4 0.0 8.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 OAJ09000.1 - 3.4e-06 26.6 0.0 4.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 OAJ09000.1 - 9.4e-06 26.3 0.0 2.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ09000.1 - 0.00011 21.8 0.9 0.01 15.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OAJ09000.1 - 0.0057 16.5 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ09000.1 - 0.011 15.1 0.1 0.025 14.0 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAJ09000.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_10 PF05971.12 OAJ09000.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_15 PF09445.10 OAJ09000.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 OAJ09000.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 OAJ09000.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ09000.1 - 0.16 12.7 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nop10p PF04135.12 OAJ09001.1 - 1.8e-07 31.1 0.1 2e-07 30.9 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF4805 PF16063.5 OAJ09004.1 - 0.12 11.7 2.6 3.2 7.0 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) DUF3439 PF11921.8 OAJ09004.1 - 0.84 9.6 5.4 1.2 9.2 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) F-box-like PF12937.7 OAJ09009.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like GTP_EFTU PF00009.27 OAJ09011.1 - 1e-53 181.8 0.0 1.5e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ09011.1 - 8.4e-40 135.6 0.0 1.9e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ09011.1 - 5.4e-14 52.3 0.8 5.4e-14 52.3 0.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ09011.1 - 0.00043 20.3 0.2 0.013 15.6 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ09011.1 - 0.078 12.7 0.1 14 5.5 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain FlpD PF02662.16 OAJ09011.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Mpp10 PF04006.12 OAJ09012.1 - 0.14 10.5 31.3 0.31 9.4 31.3 1.5 1 1 0 1 1 1 0 Mpp10 protein Herpes_TAF50 PF03326.13 OAJ09012.1 - 0.44 9.2 1.0 0.61 8.7 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Glyco_trans_4_4 PF13579.6 OAJ09016.1 - 8.1e-10 39.4 5.8 1.6e-09 38.4 3.5 2.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 OAJ09016.1 - 9.4e-08 32.6 0.0 4e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ09016.1 - 5.5e-05 23.2 1.9 0.00011 22.2 1.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ09016.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAJ09016.1 - 0.00086 19.7 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 RVT_2 PF07727.14 OAJ09017.1 - 2.1e-61 207.6 0.0 2.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 OAJ09017.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 MPM1 PF17234.2 OAJ09017.1 - 0.21 11.8 0.0 5.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 4HBT PF03061.22 OAJ09022.1 - 0.008 16.5 0.5 0.036 14.4 0.0 2.3 3 0 0 3 3 3 1 Thioesterase superfamily Apolipoprotein PF01442.18 OAJ09023.1 - 0.091 12.6 8.1 0.2 11.5 8.1 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain UPF0560 PF10577.9 OAJ09024.1 - 7.1 5.0 9.9 11 4.4 9.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PepSY_TM PF03929.16 OAJ09027.1 - 0.32 10.6 0.1 0.32 10.6 0.1 2.7 3 0 0 3 3 3 0 PepSY-associated TM region Solute_trans_a PF03619.16 OAJ09028.1 - 0.014 14.9 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha RT_RNaseH_2 PF17919.1 OAJ09032.1 - 2.3e-25 88.6 0.0 5.8e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09032.1 - 9.4e-25 87.4 0.0 1.7e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ09032.1 - 2.5e-18 66.3 0.0 2.3e-12 47.1 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09032.1 - 2.2e-13 50.1 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09032.1 - 2.5e-11 43.8 0.0 7.7e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09032.1 - 0.00065 20.3 0.1 0.0036 17.9 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09032.1 - 0.021 15.4 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease YL1 PF05764.13 OAJ09037.1 - 4.9 7.2 11.0 6.1 6.9 9.5 2.0 1 1 0 1 1 1 0 YL1 nuclear protein PGA2 PF07543.12 OAJ09037.1 - 8.2 6.4 7.6 0.63 10.0 1.7 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DDE_3 PF13358.6 OAJ09038.1 - 1.1e-25 90.1 0.0 1.6e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ09038.1 - 3.1e-07 29.9 0.6 2.7e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ09038.1 - 0.00012 22.6 0.3 0.011 16.4 0.3 2.7 1 1 1 2 2 2 1 Homeodomain-like domain DDE_1 PF03184.19 OAJ09038.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Peptidase_M28 PF04389.17 OAJ09041.1 - 1.7e-26 93.2 0.0 3.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAJ09041.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cyclin_N PF00134.23 OAJ09042.1 - 4.9e-42 142.7 0.3 1.2e-41 141.4 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ09042.1 - 5.5e-29 100.7 0.0 1.5e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Gemini_AL3 PF01407.17 OAJ09042.1 - 0.097 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AL3 protein TP2 PF01254.18 OAJ09050.1 - 0.009 16.6 2.5 0.011 16.4 2.5 1.3 1 0 0 1 1 1 1 Nuclear transition protein 2 LRR_4 PF12799.7 OAJ09055.1 - 0.0041 17.5 0.5 0.12 12.8 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) DnaJ-X PF14308.6 OAJ09056.1 - 1.1e-48 165.5 1.0 2.7e-48 164.2 1.0 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAJ09056.1 - 7.6e-25 86.8 0.3 7.6e-25 86.8 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain Tmemb_55A PF09788.9 OAJ09056.1 - 0.13 11.4 0.8 0.23 10.5 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A HA2 PF04408.23 OAJ09056.1 - 4.1 7.7 7.7 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 Helicase associated domain (HA2) NOG1_N PF17835.1 OAJ09056.1 - 7 6.6 8.2 2.2 8.2 1.2 2.7 2 0 0 2 2 2 0 NOG1 N-terminal helical domain Ribonucleas_3_3 PF14622.6 OAJ09058.1 - 1.5e-06 28.4 0.0 0.14 12.4 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAJ09058.1 - 7e-05 23.4 0.0 0.00019 22.0 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 OAJ09058.1 - 0.085 13.6 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif WD40 PF00400.32 OAJ09059.1 - 1.2e-37 127.3 12.7 2.1e-10 41.0 0.6 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09059.1 - 3.2e-12 46.6 0.7 0.0054 17.0 0.0 4.4 3 2 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ09059.1 - 0.00039 19.5 0.0 5.5 5.9 0.0 4.6 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 OAJ09059.1 - 0.00069 18.6 0.1 0.0018 17.3 0.1 1.7 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 OAJ09059.1 - 0.0022 16.7 4.3 1.1 7.9 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 OAJ09059.1 - 0.0041 16.5 1.7 0.26 10.5 0.2 3.8 4 1 1 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ndc1_Nup PF09531.10 OAJ09059.1 - 0.027 13.2 0.8 0.044 12.5 0.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 OAJ09059.1 - 2.3 8.1 5.7 3.3 7.6 5.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribosomal_L35Ae PF01247.18 OAJ09060.1 - 1e-40 137.8 0.3 1.1e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAJ09060.1 - 0.059 13.6 0.1 9.3 6.5 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain IPPT PF01715.17 OAJ09061.1 - 7.9e-11 42.2 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 IPP transferase AAA_22 PF13401.6 OAJ09061.1 - 0.004 17.4 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ09061.1 - 0.0057 17.2 0.1 0.0058 17.2 0.1 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OAJ09061.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 OAJ09061.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain IPT PF01745.16 OAJ09061.1 - 0.016 14.6 0.4 0.23 10.8 0.4 2.0 1 1 0 1 1 1 0 Isopentenyl transferase AAA_28 PF13521.6 OAJ09061.1 - 0.016 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ09061.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OAJ09061.1 - 0.032 14.4 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_L2_C PF03947.18 OAJ09061.1 - 0.035 14.3 0.0 0.058 13.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain AAA_25 PF13481.6 OAJ09061.1 - 0.076 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ09061.1 - 0.097 11.8 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Semialdhyde_dh PF01118.24 OAJ09061.1 - 0.12 12.8 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain VID27_N PF17748.1 OAJ09065.1 - 7.6e-08 32.4 1.0 1.1e-07 31.8 0.8 1.3 1 1 0 1 1 1 1 VID27 N-terminal region 2OG-FeII_Oxy_3 PF13640.6 OAJ09066.1 - 1.6e-07 32.1 0.1 3.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1885 PF08968.10 OAJ09066.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Pkinase PF00069.25 OAJ09069.1 - 2.8e-25 89.2 0.0 5e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09069.1 - 9.9e-13 48.0 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ09069.1 - 0.0013 17.5 0.0 0.0028 16.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase DDE_1 PF03184.19 OAJ09070.1 - 9e-19 67.8 1.5 6.7e-17 61.7 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Ribosomal_60s PF00428.19 OAJ09070.1 - 0.024 15.2 5.8 0.048 14.3 3.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4336 PF14234.6 OAJ09076.1 - 0.0003 20.1 0.0 0.18 11.0 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) ODV-E18 PF10717.9 OAJ09077.1 - 0.031 14.2 0.4 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Heme_oxygenase PF01126.20 OAJ09078.1 - 4.5e-08 33.1 0.0 4.2e-06 26.7 0.0 2.9 3 1 0 3 3 3 2 Heme oxygenase PWWP PF00855.17 OAJ09085.1 - 9.5e-18 64.4 0.1 4.5e-17 62.2 0.1 2.2 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 OAJ09085.1 - 5.4e-07 29.5 0.2 2.6e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Abhydrolase_3 PF07859.13 OAJ09086.1 - 7.1e-23 81.6 0.0 8.7e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAJ09086.1 - 0.0017 17.9 0.1 0.072 12.6 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.22 OAJ09086.1 - 0.0031 17.5 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 OAJ09086.1 - 0.018 14.5 0.0 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ras PF00071.22 OAJ09087.1 - 2.5e-50 170.2 0.2 3.5e-50 169.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ09087.1 - 1.4e-28 99.5 0.0 2.7e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ09087.1 - 6.6e-11 42.0 0.0 2.2e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ09087.1 - 1.1e-05 25.5 0.0 2.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ09087.1 - 0.00075 19.1 0.1 0.0027 17.2 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ09087.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OAJ09087.1 - 0.018 15.1 0.4 0.041 13.9 0.4 1.9 1 1 0 1 1 1 0 Dynamin family DUF89 PF01937.19 OAJ09087.1 - 0.029 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 Herpes_gI PF01688.17 OAJ09093.1 - 0.06 13.3 0.7 0.25 11.3 0.1 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein I RVT_3 PF13456.6 OAJ09095.1 - 0.0021 17.9 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.27 OAJ09095.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAJ09095.1 - 0.0086 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.22 OAJ09096.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family Exo_endo_phos PF03372.23 OAJ09102.1 - 5.4e-07 29.4 0.0 1.2e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 OAJ09103.1 - 5.8e-27 94.5 34.5 1.1e-26 93.6 33.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ09103.1 - 7.5e-11 41.5 17.4 1.8e-10 40.3 6.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4834 PF16118.5 OAJ09108.1 - 2.2 9.3 9.9 3.7 8.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_S10 PF00450.22 OAJ09109.1 - 9.1e-84 282.3 0.0 7.3e-81 272.7 0.0 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase MAT1-1-2 PF17043.5 OAJ09109.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function Myb_DNA-binding PF00249.31 OAJ09110.1 - 2.7e-17 62.7 5.6 1.4e-12 47.6 0.8 3.3 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ09110.1 - 4.7e-10 39.6 14.4 2.1e-08 34.3 0.3 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ09110.1 - 0.00017 21.7 0.6 0.0061 16.7 0.0 2.9 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OAJ09110.1 - 0.0054 17.1 10.9 0.016 15.5 0.5 3.7 2 2 1 3 3 3 2 Myb/SANT-like DNA-binding domain HTH_23 PF13384.6 OAJ09110.1 - 0.097 12.5 0.3 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Homeodomain-like domain MADF_DNA_bdg PF10545.9 OAJ09110.1 - 2 8.8 10.9 2.9 8.3 0.1 4.2 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1793 PF08760.11 OAJ09115.1 - 2.3e-66 223.3 0.6 4.3e-66 222.5 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAJ09115.1 - 4.3e-09 36.3 0.1 9.4e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DEAD PF00270.29 OAJ09120.1 - 0.081 12.7 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase Mto2_bdg PF12808.7 OAJ09125.1 - 0.0013 19.0 0.3 0.0063 16.8 0.1 2.0 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region ATG16 PF08614.11 OAJ09125.1 - 0.0087 16.3 0.4 0.012 15.8 0.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OAJ09125.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 OAJ09125.1 - 0.03 13.4 0.1 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_1 PF00078.27 OAJ09130.1 - 2.2e-22 79.7 0.0 3.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09130.1 - 1.2e-18 67.0 0.0 1.2e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09130.1 - 1.5e-15 57.1 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ09130.1 - 7.3e-13 48.7 0.0 4.8e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09130.1 - 2.5e-11 43.8 0.1 6e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09130.1 - 1.7e-05 25.3 0.1 8.4e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09130.1 - 0.0016 19.0 0.0 0.0063 17.1 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease PepSY_2 PF13670.6 OAJ09135.1 - 0.16 12.0 0.7 0.21 11.6 0.7 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ubiquitin PF00240.23 OAJ09143.1 - 0.016 14.9 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family Holin_SPP1 PF04688.13 OAJ09144.1 - 0.037 14.2 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 SPP1 phage holin Ldh_1_N PF00056.23 OAJ09147.1 - 1.7e-46 157.9 0.5 2.4e-46 157.3 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAJ09147.1 - 4.9e-46 156.7 0.0 7.9e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 OAJ09147.1 - 3.7e-06 26.2 0.0 6.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAJ09147.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 OAJ09147.1 - 0.003 16.9 0.3 0.048 13.0 0.3 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 OAJ09147.1 - 0.02 14.5 0.2 0.97 9.0 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Mito_carr PF00153.27 OAJ09148.1 - 1.2e-31 108.5 2.6 6.1e-17 61.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Thi4 PF01946.17 OAJ09153.1 - 2.1e-13 50.1 0.0 2.4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Thi4 family TPR_12 PF13424.6 OAJ09154.1 - 9.8e-05 22.6 10.9 0.046 14.0 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ09154.1 - 0.025 15.1 1.2 0.09 13.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ09154.1 - 0.03 14.5 0.0 19 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ09154.1 - 0.035 14.0 1.2 9.2 6.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Gpr1_Fun34_YaaH PF01184.19 OAJ09154.1 - 0.17 11.5 0.6 0.27 10.8 0.6 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family TPR_2 PF07719.17 OAJ09154.1 - 0.18 12.0 1.2 17 5.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_45 PF02015.16 OAJ09157.1 - 6.8e-52 176.4 3.6 8.5e-52 176.1 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.14 OAJ09157.1 - 1.3 8.4 13.8 1.9 7.8 13.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region YL1 PF05764.13 OAJ09158.1 - 0.018 15.2 12.0 0.018 15.2 12.0 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Na_trans_assoc PF06512.13 OAJ09158.1 - 0.021 15.1 4.8 0.029 14.7 4.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 OAJ09158.1 - 0.031 12.5 15.3 0.039 12.2 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 OAJ09158.1 - 0.037 13.9 4.4 0.047 13.6 4.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SDA1 PF05285.12 OAJ09158.1 - 0.13 11.6 11.5 0.18 11.2 11.5 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 OAJ09158.1 - 0.19 11.3 10.7 0.14 11.7 9.5 1.4 2 0 0 2 2 2 0 PPP4R2 TRAP_alpha PF03896.16 OAJ09158.1 - 0.37 9.9 3.8 0.5 9.5 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 OAJ09158.1 - 0.46 8.7 8.4 0.64 8.2 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 OAJ09158.1 - 0.87 9.5 10.1 1.1 9.1 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OAJ09158.1 - 1.6 8.0 12.6 2.1 7.6 12.6 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 OAJ09158.1 - 2 8.3 11.1 2.7 7.8 11.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Tom22 PF04281.13 OAJ09158.1 - 2.1 8.1 5.1 3.5 7.4 5.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RRN3 PF05327.11 OAJ09158.1 - 3.7 6.0 10.0 4.7 5.6 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ09158.1 - 7.6 4.5 22.8 10 4.1 22.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 OAJ09158.1 - 9.3 5.8 9.0 15 5.1 9.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PhoLip_ATPase_C PF16212.5 OAJ09162.1 - 1e-72 244.9 30.2 1e-72 244.9 30.2 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ09162.1 - 4.4e-21 74.3 0.8 4.4e-21 74.3 0.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAJ09162.1 - 1.5e-12 48.3 0.9 6.2e-05 23.4 0.7 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ09162.1 - 1.4e-11 44.3 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAJ09162.1 - 4.8e-06 26.2 0.0 4.8e-06 26.2 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ09162.1 - 0.0026 17.5 0.1 0.0073 16.1 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP1_TM PF14812.6 OAJ09162.1 - 1.2 9.6 3.8 5.1 7.5 3.8 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_1 PF00078.27 OAJ09170.1 - 4e-26 91.9 0.0 5.8e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 OAJ09175.1 - 6.5e-60 202.8 0.0 9.7e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09175.1 - 3e-16 59.7 0.1 5.3e-14 52.4 0.0 3.4 3 0 0 3 3 3 1 Integrase core domain zf-CCHC PF00098.23 OAJ09175.1 - 4.3e-07 29.7 1.6 1.1e-06 28.4 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 OAJ09175.1 - 5.6e-07 29.3 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09175.1 - 0.00045 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ09175.1 - 0.00071 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HU-HIG PF18291.1 OAJ09176.1 - 0.095 12.8 0.0 8.2 6.5 0.0 2.0 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif SAP18 PF06487.12 OAJ09180.1 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) UPF0254 PF06787.11 OAJ09180.1 - 0.02 14.7 0.2 0.029 14.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Ribosomal_60s PF00428.19 OAJ09180.1 - 0.17 12.5 16.3 0.47 11.1 2.1 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF5320 PF17253.2 OAJ09180.1 - 1.2 10.2 0.0 1.2 10.2 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DnaJ PF00226.31 OAJ09187.1 - 1.7e-15 56.9 0.1 3.5e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain SUIM_assoc PF16619.5 OAJ09187.1 - 0.00041 20.4 0.0 0.098 12.7 0.0 2.8 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 PDGLE PF13190.6 OAJ09188.1 - 0.073 13.0 1.7 3.1 7.8 0.4 2.5 2 1 0 2 2 2 0 PDGLE domain Gly_reductase PF09338.11 OAJ09188.1 - 0.21 9.9 2.0 5 5.4 0.0 2.0 2 0 0 2 2 2 0 Glycine/sarcosine/betaine reductase component B subunits SCHIP-1 PF10148.9 OAJ09188.1 - 0.64 9.6 1.5 0.85 9.2 1.5 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 zf-CCHC PF00098.23 OAJ09191.1 - 0.00015 21.7 1.5 0.00034 20.5 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ09191.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 OAJ09192.1 - 9e-70 235.1 0.0 1.2e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nucleocapsid-N PF11030.8 OAJ09195.1 - 0.034 14.1 4.1 0.057 13.4 4.1 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N IF4E PF01652.18 OAJ09196.1 - 3.2e-46 157.0 0.3 1e-45 155.4 0.3 1.7 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Thymidylat_synt PF00303.19 OAJ09201.1 - 2.2e-90 302.5 0.0 3.2e-90 301.9 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 OAJ09201.1 - 3e-37 128.2 2.0 4.2e-36 124.5 2.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SDA1 PF05285.12 OAJ09205.1 - 4.8e-05 23.0 25.5 4.8e-05 23.0 25.5 2.5 2 0 0 2 2 2 1 SDA1 GAS PF13851.6 OAJ09205.1 - 0.77 9.1 23.9 1.2 8.4 12.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OAJ09205.1 - 1.2 9.2 9.8 0.087 12.9 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RVT_2 PF07727.14 OAJ09207.1 - 4e-68 229.7 0.0 5.4e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09207.1 - 1.5e-15 57.4 0.0 3.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09207.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09207.1 - 0.0002 21.1 1.1 0.0033 17.2 0.3 2.9 2 1 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ09207.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAJ09209.1 - 0.00043 20.2 1.2 0.0011 19.0 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ09209.1 - 0.003 17.4 1.3 0.0061 16.4 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ09209.1 - 0.0066 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Herpes_capsid PF06112.11 OAJ09209.1 - 0.099 12.7 2.1 0.81 9.7 0.2 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Copper-fist PF00649.18 OAJ09209.1 - 0.2 11.2 0.8 0.51 9.9 0.8 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain RT_RNaseH_2 PF17919.1 OAJ09219.1 - 3.4e-27 94.4 0.0 7e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09219.1 - 2.4e-24 85.6 0.0 5.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09219.1 - 3.2e-20 72.6 0.0 5.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09219.1 - 4e-14 52.8 0.2 1.7e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ09219.1 - 4.1e-14 52.4 0.2 1.2e-13 50.9 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 OAJ09219.1 - 3.2e-05 23.8 0.7 3.2e-05 23.8 0.7 1.9 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 OAJ09219.1 - 0.0014 18.4 0.0 0.0049 16.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 OAJ09219.1 - 0.0017 18.6 0.9 0.011 16.0 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ09221.1 - 0.00016 21.6 1.5 0.00034 20.6 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ09221.1 - 0.00017 21.3 0.0 0.00047 19.8 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF3350 PF11830.8 OAJ09221.1 - 0.13 12.5 0.1 0.48 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) RVT_2 PF07727.14 OAJ09222.1 - 6.3e-10 39.1 0.1 8.8e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metal_resist PF13801.6 OAJ09222.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.9 4 0 0 4 4 4 0 Heavy-metal resistance RVT_2 PF07727.14 OAJ09223.1 - 8.9e-45 153.2 0.0 1.2e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACOX PF01756.19 OAJ09232.1 - 1.7e-44 151.5 0.8 4.1e-44 150.3 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAJ09232.1 - 5.4e-22 78.7 0.1 1.2e-21 77.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAJ09232.1 - 4.4e-09 36.4 0.0 7.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ09232.1 - 5.8e-06 26.6 0.3 0.00032 21.0 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ09232.1 - 0.07 13.8 0.0 0.23 12.2 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain MULE PF10551.9 OAJ09240.1 - 3e-08 33.9 0.1 1.2e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.15 OAJ09240.1 - 3.6e-05 24.4 0.4 0.00011 22.8 0.0 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF5575 PF17738.1 OAJ09240.1 - 0.014 14.4 0.0 0.62 9.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5575) rve PF00665.26 OAJ09240.1 - 0.016 15.4 0.1 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain KdpC PF02669.15 OAJ09240.1 - 0.14 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain ANAPC15 PF15243.6 OAJ09246.1 - 0.01 16.2 3.0 0.024 15.0 3.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop14 PF04147.12 OAJ09246.1 - 0.97 7.6 3.2 1.3 7.1 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAJ09246.1 - 1.1 8.5 6.8 1.9 7.7 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ09246.1 - 4.4 5.3 7.5 5.8 4.9 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_2 PF13639.6 OAJ09254.1 - 4.6e-08 33.3 11.6 7.1e-08 32.7 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAJ09254.1 - 0.00032 20.4 7.9 0.00061 19.5 7.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ09254.1 - 0.00055 19.7 9.9 0.00085 19.1 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ09254.1 - 0.0044 17.0 10.4 0.0067 16.4 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ09254.1 - 0.013 15.3 10.2 0.02 14.7 10.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ09254.1 - 0.64 10.3 9.9 1.8 8.9 9.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAJ09254.1 - 2.4 8.1 10.5 3.8 7.5 10.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ09254.1 - 4.2 7.3 9.7 7.3 6.5 9.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CRCB PF02537.15 OAJ09255.1 - 1.8e-24 85.9 19.2 5.9e-15 55.3 4.8 2.7 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) U3snoRNP10 PF12397.8 OAJ09260.1 - 0.15 12.4 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Asp_protease_2 PF13650.6 OAJ09261.1 - 2e-05 25.1 0.1 5e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09261.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease dUTPase PF00692.19 OAJ09261.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 dUTPase Retrotrans_gag PF03732.17 OAJ09261.1 - 0.016 15.5 0.2 0.029 14.6 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 OAJ09261.1 - 0.082 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 OAJ09267.1 - 1e-31 108.9 0.0 1.9e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09267.1 - 9.7e-29 99.8 0.0 2.1e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09267.1 - 4.3e-10 39.8 0.0 1.1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ09267.1 - 2.1e-09 37.3 0.0 3.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 OAJ09267.1 - 0.087 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF1571 PF07608.11 OAJ09268.1 - 0.082 12.3 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) zf-CCHC PF00098.23 OAJ09268.1 - 2.3 8.4 7.9 17 5.7 3.0 2.8 2 0 0 2 2 2 0 Zinc knuckle Bax1-I PF01027.20 OAJ09274.1 - 2.4e-36 125.5 7.4 4.3e-36 124.7 7.4 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CitT PF12431.8 OAJ09275.1 - 0.00011 22.5 1.1 2.2 8.7 0.0 4.4 3 0 0 3 3 3 2 Transcriptional regulator BSP_II PF05432.11 OAJ09275.1 - 8.3 6.0 11.8 0.65 9.6 6.4 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RPA43_OB PF17875.1 OAJ09280.1 - 2.2e-14 54.1 0.0 2.2e-14 54.1 0.0 3.8 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAJ09280.1 - 2.8e-06 27.6 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cwf_Cwc_15 PF04889.12 OAJ09280.1 - 0.00013 21.8 21.5 0.00013 21.8 21.5 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 OAJ09280.1 - 1.9 8.3 27.8 0.045 13.6 18.5 2.2 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Alg14 PF08660.11 OAJ09281.1 - 1.9e-49 168.0 0.0 5.7e-49 166.4 0.0 1.7 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Atg14 PF10186.9 OAJ09282.1 - 4.8e-08 32.4 7.3 1e-07 31.4 7.3 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ALO PF04030.14 OAJ09282.1 - 0.031 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Adeno_E3 PF06040.11 OAJ09282.1 - 0.17 12.1 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 protein Exonuc_VII_L PF02601.15 OAJ09282.1 - 0.3 10.6 8.0 0.57 9.7 8.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 OAJ09282.1 - 10 6.2 15.8 0.1 12.7 6.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BES1_N PF05687.13 OAJ09288.1 - 0.1 13.0 2.2 0.12 12.8 2.2 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Ribosomal_60s PF00428.19 OAJ09288.1 - 0.51 11.0 11.0 0.16 12.6 8.4 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF563 PF04577.14 OAJ09288.1 - 0.56 10.3 1.4 0.65 10.1 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF563) DUF2967 PF11179.8 OAJ09288.1 - 1.8 6.6 3.7 1.7 6.7 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Cytomega_UL84 PF06284.11 OAJ09288.1 - 2.3 6.5 4.1 2.6 6.4 4.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FAM176 PF14851.6 OAJ09288.1 - 2.4 7.8 10.8 2.6 7.7 10.8 1.0 1 0 0 1 1 1 0 FAM176 family Ras PF00071.22 OAJ09289.1 - 2.7e-33 114.8 0.5 6.3e-16 58.4 0.1 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 OAJ09289.1 - 4.3e-12 46.3 0.1 5.7e-11 42.7 0.0 2.1 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OAJ09289.1 - 0.00081 19.3 0.3 0.31 10.9 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OAJ09289.1 - 0.012 15.0 0.0 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ09289.1 - 0.025 14.6 0.1 0.031 14.4 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ09289.1 - 0.033 13.7 0.0 7.5 6.1 0.0 2.2 1 1 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 OAJ09289.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 OAJ09289.1 - 0.066 13.5 0.0 0.098 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain TMEM237 PF15383.6 OAJ09290.1 - 0.00032 19.9 0.0 0.00087 18.5 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 237 Sugarporin_N PF11471.8 OAJ09290.1 - 0.042 13.8 2.5 0.12 12.3 2.5 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF4279 PF14106.6 OAJ09290.1 - 0.25 11.5 1.0 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) WD40 PF00400.32 OAJ09291.1 - 3.5e-51 170.1 24.8 3.1e-09 37.3 0.6 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09291.1 - 1.1e-17 64.1 0.4 5e-05 23.5 0.0 5.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ09291.1 - 3.3e-08 32.7 3.8 0.77 8.3 0.0 5.9 3 1 2 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 OAJ09291.1 - 3.7e-08 33.5 0.0 0.00085 19.2 0.0 3.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 OAJ09291.1 - 9.9e-07 28.0 2.9 0.0086 15.0 0.0 4.6 2 1 3 5 5 5 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OAJ09291.1 - 1.4e-05 24.2 0.2 0.66 8.9 0.0 4.7 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ09291.1 - 0.00037 19.9 0.1 0.0038 16.6 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain Frtz PF11768.8 OAJ09291.1 - 0.0087 14.4 0.1 0.023 13.0 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz SR-25 PF10500.9 OAJ09291.1 - 0.78 9.3 5.7 1.8 8.1 5.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Baculo_PEP_C PF04513.12 OAJ09295.1 - 0.21 11.6 0.1 0.5 10.4 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_1 PF00078.27 OAJ09296.1 - 3.8e-23 82.2 0.0 6.5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09296.1 - 1.8e-15 56.8 0.0 4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09296.1 - 2e-13 50.2 0.0 4.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09296.1 - 1.1e-12 48.2 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09296.1 - 7.1e-06 26.6 0.0 2.5e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09296.1 - 0.00035 21.1 0.0 0.0011 19.4 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ09296.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ09296.1 - 0.14 12.4 0.0 0.67 10.3 0.0 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09297.1 - 1.5e-09 38.1 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09297.1 - 4.7e-07 29.8 0.0 8.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3712 PF12505.8 OAJ09303.1 - 1.2e-24 87.0 0.3 5e-12 46.2 0.0 4.6 3 1 0 3 3 3 3 Protein of unknown function (DUF3712) Pkinase PF00069.25 OAJ09309.1 - 2.3e-24 86.2 0.0 3.2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09309.1 - 6.8e-11 41.9 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RTC4 PF14474.6 OAJ09309.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.6 1 1 0 1 1 1 1 RTC4-like domain Kdo PF06293.14 OAJ09309.1 - 0.0027 17.1 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAJ09309.1 - 0.032 13.2 0.4 0.046 12.7 0.4 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AphA_like PF14557.6 OAJ09318.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Apt1 PF10351.9 OAJ09325.1 - 1 8.2 8.0 1.3 7.8 8.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 OAJ09325.1 - 3.8 5.7 9.7 5 5.3 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GREB1 PF15782.5 OAJ09325.1 - 6.9 3.6 8.7 8.4 3.4 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Syndecan PF01034.20 OAJ09326.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 OAJ09326.1 - 0.074 12.5 0.0 0.074 12.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ABC_membrane PF00664.23 OAJ09330.1 - 3.8e-73 246.5 23.2 5e-38 131.3 9.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ09330.1 - 4.5e-59 198.9 0.0 5.9e-29 101.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ09330.1 - 1.5e-16 60.5 1.9 3.7e-08 33.1 0.5 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ09330.1 - 2.1e-09 37.5 0.1 0.0015 18.5 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 OAJ09330.1 - 2.5e-07 30.8 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ09330.1 - 2.8e-07 30.2 2.5 0.0019 17.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ09330.1 - 7.2e-06 26.3 0.3 0.036 14.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAJ09330.1 - 3.5e-05 24.3 0.2 0.044 14.3 0.1 3.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OAJ09330.1 - 0.00019 21.9 5.5 0.095 13.1 1.4 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 OAJ09330.1 - 0.00028 20.5 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ09330.1 - 0.0003 21.0 0.9 0.025 14.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 OAJ09330.1 - 0.00045 19.2 0.3 0.3 9.8 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAJ09330.1 - 0.002 17.7 0.5 0.41 10.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 OAJ09330.1 - 0.0022 18.4 0.3 0.69 10.3 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OAJ09330.1 - 0.0027 17.5 0.1 0.61 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ09330.1 - 0.0034 17.4 0.1 4 7.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OAJ09330.1 - 0.0037 17.8 2.3 0.14 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF3987 PF13148.6 OAJ09330.1 - 0.0063 15.6 5.8 0.039 13.0 1.2 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) T2SSE PF00437.20 OAJ09330.1 - 0.01 14.9 0.0 0.2 10.7 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF87 PF01935.17 OAJ09330.1 - 0.023 14.8 0.7 0.51 10.4 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 OAJ09330.1 - 0.031 14.5 4.6 2.1 8.7 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 OAJ09330.1 - 0.041 13.2 1.6 0.83 8.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.22 OAJ09330.1 - 0.056 13.8 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Hep_59 PF07052.11 OAJ09330.1 - 0.075 13.8 0.8 0.24 12.2 0.8 1.8 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 IstB_IS21 PF01695.17 OAJ09330.1 - 0.092 12.5 0.0 5 6.8 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 OAJ09330.1 - 0.11 12.5 0.0 4.2 7.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 OAJ09330.1 - 0.13 12.3 0.8 16 5.5 0.1 2.8 3 0 0 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 OAJ09330.1 - 1.2 8.5 3.8 6 6.1 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family PIF1 PF05970.14 OAJ09335.1 - 3.4e-55 187.7 0.0 5.1e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ09335.1 - 3e-11 43.4 0.0 4.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ09335.1 - 0.0002 21.7 0.2 0.00071 19.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ09335.1 - 0.0033 17.9 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 OAJ09335.1 - 0.0048 15.9 0.1 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 OAJ09335.1 - 0.0065 16.9 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAJ09335.1 - 0.018 15.0 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAJ09335.1 - 0.019 14.8 0.0 0.086 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAJ09335.1 - 0.045 13.0 0.1 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OAJ09335.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PIGA PF08288.12 OAJ09343.1 - 2.5e-40 136.9 0.0 5.2e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAJ09343.1 - 2.7e-29 102.3 1.1 4.8e-29 101.5 1.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ09343.1 - 7.5e-23 80.9 0.0 1.1e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ09343.1 - 1.1e-19 71.2 0.0 2.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ09343.1 - 3e-14 53.8 1.2 7.4e-14 52.5 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OAJ09343.1 - 8.8e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OAJ09343.1 - 0.0021 18.4 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tho1_MOS11_C PF18592.1 OAJ09344.1 - 1.1e-09 37.9 13.0 4.6e-08 32.7 0.2 3.1 2 1 1 3 3 3 3 Tho1/MOS11 C-terminal domain Homeodomain PF00046.29 OAJ09349.1 - 1.2e-13 50.7 0.5 3.2e-13 49.3 0.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAJ09349.1 - 0.00023 21.0 0.8 0.00057 19.7 0.8 1.7 1 0 0 1 1 1 1 Homeobox KN domain RRN3 PF05327.11 OAJ09349.1 - 0.055 12.0 0.5 0.092 11.3 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cytochrome-c551 PF10643.9 OAJ09349.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 YL1 PF05764.13 OAJ09349.1 - 2 8.5 11.5 3.4 7.7 11.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Homeobox_KN PF05920.11 OAJ09350.1 - 3.5e-05 23.6 0.0 0.0001 22.1 0.0 1.9 1 1 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.12 OAJ09350.1 - 0.023 14.2 0.2 0.023 14.2 0.2 3.2 3 1 0 3 3 3 0 Ustilago B locus mating-type protein BSP_II PF05432.11 OAJ09359.1 - 0.01 15.5 11.5 0.019 14.7 11.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myb_DNA-bind_3 PF12776.7 OAJ09365.1 - 1.3e-20 74.1 1.4 2.3e-20 73.4 1.4 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ09365.1 - 4.9e-08 33.3 2.0 1.2e-07 32.0 2.0 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ09365.1 - 0.045 14.0 0.9 0.12 12.6 0.9 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ09365.1 - 0.63 10.3 5.1 1.7 8.9 5.1 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain AAA PF00004.29 OAJ09368.1 - 1.7e-40 138.5 0.0 3.3e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAJ09368.1 - 9.8e-27 92.7 0.1 3.2e-26 91.1 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAJ09368.1 - 2.4e-22 78.8 8.9 5.2e-22 77.7 8.9 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OAJ09368.1 - 1.3e-08 34.5 0.0 2.2e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OAJ09368.1 - 4.7e-05 23.8 0.1 0.0073 16.7 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 OAJ09368.1 - 9.2e-05 21.8 0.4 0.00022 20.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 OAJ09368.1 - 0.00019 21.2 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ09368.1 - 0.00027 20.9 0.0 0.00079 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ09368.1 - 0.00036 20.3 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OAJ09368.1 - 0.00058 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ09368.1 - 0.00059 20.1 0.1 0.051 13.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAJ09368.1 - 0.0016 18.8 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAJ09368.1 - 0.0029 17.6 0.2 0.0099 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ09368.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OAJ09368.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 OAJ09368.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OAJ09368.1 - 0.017 15.5 0.1 0.051 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 OAJ09368.1 - 0.019 15.5 0.1 0.1 13.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAJ09368.1 - 0.02 14.5 0.1 0.95 9.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ09368.1 - 0.055 13.2 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAJ09368.1 - 0.06 12.7 0.0 6 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 OAJ09368.1 - 0.12 12.1 0.0 0.58 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ09368.1 - 0.18 11.7 0.0 0.82 9.6 0.0 2.2 2 1 0 2 2 2 0 NACHT domain PhoH PF02562.16 OAJ09368.1 - 0.28 10.6 1.2 0.39 10.1 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein PEMT PF04191.13 OAJ09369.1 - 9.3e-22 77.4 0.9 9.3e-22 77.4 0.9 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase EBV-NA3 PF05009.12 OAJ09369.1 - 0.072 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SNF2_N PF00176.23 OAJ09374.1 - 7e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ09374.1 - 0.075 13.4 0.0 0.39 11.1 0.0 2.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain PPI_Ypi1 PF07491.11 OAJ09381.1 - 2.6e-23 81.6 4.2 2.6e-23 81.6 4.2 2.6 2 1 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.14 OAJ09381.1 - 0.67 8.2 11.3 1.4 7.1 11.3 1.5 1 1 0 1 1 1 0 CDC45-like protein Histidinol_dh PF00815.20 OAJ09382.1 - 2.4e-147 491.2 0.7 4.3e-147 490.4 0.7 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAJ09382.1 - 3.5e-21 74.8 0.2 7.2e-21 73.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAJ09382.1 - 5.5e-15 55.6 0.8 3.6e-14 53.0 1.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OAJ09382.1 - 0.0028 17.8 0.2 0.0058 16.8 0.2 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF460 PF04312.13 OAJ09382.1 - 0.0075 16.0 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF460) MazG-like PF12643.7 OAJ09382.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 MazG-like family Elf1 PF05129.13 OAJ09387.1 - 1.3 9.1 8.3 0.44 10.6 4.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 OAJ09387.1 - 1.9 8.5 12.1 2.8 7.9 4.5 2.7 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Acyl_transf_3 PF01757.22 OAJ09400.1 - 6.1e-17 61.7 42.9 1.5e-16 60.4 42.9 1.7 1 1 0 1 1 1 1 Acyltransferase family Presenilin PF01080.17 OAJ09400.1 - 0.057 12.2 1.8 0.11 11.2 1.8 1.4 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 OAJ09405.1 - 3.5e-24 85.6 0.0 6.3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09405.1 - 6.7e-22 77.4 0.0 1.7e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09405.1 - 6.3e-17 61.8 0.0 7.4e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09405.1 - 3.4e-12 46.3 0.1 6e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09405.1 - 2e-09 37.6 0.0 4.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09405.1 - 0.0069 17.0 0.0 0.025 15.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ09405.1 - 0.045 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger EcKinase PF02958.20 OAJ09411.1 - 9.9e-12 44.8 0.0 3.7e-10 39.6 0.0 2.6 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OAJ09411.1 - 2.3e-07 30.0 0.0 3.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 OAJ09411.1 - 7.8e-07 29.3 1.0 1.6e-06 28.2 1.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4407 PF14362.6 OAJ09412.1 - 0.22 10.9 9.1 1 8.7 5.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) NDC10_II PF16787.5 OAJ09417.1 - 1.2e-47 162.5 0.0 2e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ09417.1 - 0.0038 17.5 0.1 0.0085 16.4 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1 PF01527.20 OAJ09417.1 - 0.027 14.8 0.3 0.26 11.6 0.0 2.8 3 0 0 3 3 3 0 Transposase HTH_29 PF13551.6 OAJ09417.1 - 0.061 13.3 0.0 0.29 11.2 0.0 2.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 OAJ09417.1 - 0.064 13.1 1.0 7.7 6.4 0.0 3.4 3 0 0 3 3 3 0 Homeodomain-like domain PXA PF02194.15 OAJ09417.1 - 0.075 13.0 0.8 0.23 11.4 0.8 1.8 1 0 0 1 1 1 0 PXA domain Phosphoesterase PF04185.14 OAJ09424.1 - 5e-26 91.7 1.4 2.1e-25 89.7 1.4 1.8 1 1 0 1 1 1 1 Phosphoesterase family Gram_pos_anchor PF00746.21 OAJ09424.1 - 1.1 9.2 4.1 4.1 7.4 0.8 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Secretin_N PF03958.17 OAJ09425.1 - 0.58 10.6 3.1 14 6.2 0.0 3.6 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain Myb_DNA-bind_4 PF13837.6 OAJ09431.1 - 0.00069 19.9 1.0 0.00069 19.9 1.0 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Cytochrom_C PF00034.21 OAJ09431.1 - 9 7.5 7.7 2.4 9.4 0.0 3.0 3 1 0 3 3 3 0 Cytochrome c DDE_Tnp_4 PF13359.6 OAJ09432.1 - 1.8e-19 70.0 0.0 4.5e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.26 OAJ09439.1 - 0.0066 16.6 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain TruB_C_2 PF16198.5 OAJ09439.1 - 0.027 14.6 0.8 0.48 10.6 0.2 2.9 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain Myb_DNA-bind_3 PF12776.7 OAJ09440.1 - 0.012 16.6 0.0 0.014 16.4 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ndc1_Nup PF09531.10 OAJ09442.1 - 0.012 14.3 4.5 0.016 13.9 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 OAJ09442.1 - 0.04 13.9 9.2 0.058 13.4 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.29 OAJ09442.1 - 0.074 12.9 10.4 0.23 11.4 10.4 1.8 1 0 0 1 1 1 0 PHD-finger Spt20 PF12090.8 OAJ09442.1 - 0.82 9.2 12.8 1.5 8.4 12.8 1.3 1 0 0 1 1 1 0 Spt20 family Pan3_PK PF18101.1 OAJ09446.1 - 6.9e-57 191.3 0.0 1.3e-56 190.4 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAJ09446.1 - 0.0078 15.6 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Thioredoxin PF00085.20 OAJ09447.1 - 1.7e-60 201.4 0.2 3.5e-26 91.2 0.0 4.4 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.6 OAJ09447.1 - 3.9e-40 137.7 0.2 2.4e-34 118.9 0.2 3.4 3 1 1 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.17 OAJ09447.1 - 2.7e-14 53.0 0.1 6.4e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 OAJ09447.1 - 3.7e-11 43.5 2.6 0.044 14.2 0.1 4.6 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ09447.1 - 1.4e-10 41.4 0.1 0.16 12.3 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ09447.1 - 2.3e-07 30.9 0.1 0.027 14.7 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 OAJ09447.1 - 4.4e-06 26.6 1.4 0.029 14.3 0.0 3.2 4 0 0 4 4 4 2 AhpC/TSA family OST3_OST6 PF04756.13 OAJ09447.1 - 5.3e-06 26.0 0.1 2.1 7.6 0.0 3.9 1 1 2 4 4 4 3 OST3 / OST6 family, transporter family Redoxin PF08534.10 OAJ09447.1 - 0.00098 18.9 0.9 4.8 6.9 0.0 3.5 3 0 0 3 3 3 1 Redoxin ERp29_N PF07912.13 OAJ09447.1 - 0.013 15.6 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 OAJ09447.1 - 0.021 15.0 3.2 1.4 9.0 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 OAJ09447.1 - 0.031 14.0 0.7 18 5.0 0.0 3.7 3 1 1 4 4 4 0 Thioredoxin TraF PF13728.6 OAJ09447.1 - 0.039 13.8 2.9 3 7.6 0.0 3.5 4 0 0 4 4 3 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OAJ09447.1 - 0.059 13.6 0.7 17 5.7 0.0 3.9 4 1 0 4 4 4 0 Glutaredoxin PTPRCAP PF15713.5 OAJ09453.1 - 0.42 10.9 17.0 0.57 10.5 17.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2457 PF10446.9 OAJ09453.1 - 0.68 9.0 29.0 0.74 8.9 29.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_Rpc4 PF05132.14 OAJ09453.1 - 1.3 9.4 4.7 1.1 9.6 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 TraH_2 PF06871.11 OAJ09453.1 - 1.4 8.5 6.5 1.7 8.2 6.5 1.2 1 0 0 1 1 1 0 TraH_2 Paf1 PF03985.13 OAJ09453.1 - 3.2 6.7 15.5 3.3 6.6 15.5 1.1 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 OAJ09453.1 - 3.4 6.5 5.6 3.2 6.6 5.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 OAJ09453.1 - 4.3 6.7 24.3 4 6.8 24.3 1.0 1 0 0 1 1 1 0 SDA1 MAP17 PF15807.5 OAJ09453.1 - 4.5 7.5 7.8 5.8 7.2 7.8 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CobT PF06213.12 OAJ09453.1 - 5.3 6.3 21.1 5.9 6.2 21.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 OAJ09453.1 - 6 4.9 24.7 5.4 5.1 24.7 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 OAJ09453.1 - 6.3 5.5 6.4 6.1 5.5 6.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 OAJ09453.1 - 7.6 5.7 20.7 7 5.9 20.7 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 OAJ09453.1 - 7.8 5.7 27.7 11 5.2 27.7 1.3 1 0 0 1 1 1 0 NOA36 protein PsbH PF00737.20 OAJ09461.1 - 0.24 11.2 3.0 10 5.9 0.3 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF2975 PF11188.8 OAJ09461.1 - 3.3 7.6 9.4 1.2 9.1 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Transposase_21 PF02992.14 OAJ09465.1 - 3.5e-09 36.2 0.1 7.7e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ09465.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pkinase PF00069.25 OAJ09468.1 - 1.4e-32 113.1 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09468.1 - 5.9e-21 74.9 0.0 7.7e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09468.1 - 0.0022 17.4 0.1 0.0063 15.9 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ09468.1 - 0.008 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ09468.1 - 0.028 14.3 0.1 0.072 13.0 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ09468.1 - 0.097 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain SSP160 PF06933.11 OAJ09469.1 - 0.11 10.6 11.9 0.16 10.1 11.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.11 OAJ09469.1 - 0.68 9.9 9.3 1.1 9.2 9.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus RVT_1 PF00078.27 OAJ09473.1 - 2e-22 79.8 0.0 3.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09473.1 - 1.1e-15 57.5 0.0 2.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09473.1 - 6.5e-14 51.8 0.0 2.6e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09473.1 - 1.8e-12 47.5 0.0 5.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09473.1 - 8.5e-05 23.1 0.1 0.00022 21.8 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ09473.1 - 0.0023 18.1 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger dUTPase PF00692.19 OAJ09473.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 dUTPase gag-asp_proteas PF13975.6 OAJ09473.1 - 0.016 15.8 0.0 0.053 14.1 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 OAJ09473.1 - 0.022 15.1 0.0 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Importin_rep_2 PF18786.1 OAJ09475.1 - 0.006 16.4 0.1 0.006 16.4 0.1 1.7 2 0 0 2 2 2 1 Importin 13 repeat Complex1_LYR_2 PF13233.6 OAJ09480.1 - 1.9e-07 31.7 0.2 6.7e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAJ09480.1 - 1.2e-05 25.2 0.5 1.2e-05 25.2 0.5 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) F-box-like PF12937.7 OAJ09481.1 - 0.0015 18.4 0.5 0.066 13.1 0.2 2.8 2 0 0 2 2 2 1 F-box-like Med21 PF11221.8 OAJ09485.1 - 0.011 16.0 7.0 0.04 14.2 7.0 2.0 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Atg14 PF10186.9 OAJ09485.1 - 0.018 14.1 1.9 0.03 13.4 1.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pex14_N PF04695.13 OAJ09485.1 - 0.16 12.6 12.1 0.036 14.7 7.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exonuc_VII_L PF02601.15 OAJ09485.1 - 0.37 10.3 5.6 0.57 9.7 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spt20 PF12090.8 OAJ09485.1 - 1.7 8.2 18.1 0.16 11.6 12.9 1.8 2 0 0 2 2 2 0 Spt20 family zf-C2H2_11 PF16622.5 OAJ09486.1 - 0.019 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type NOA36 PF06524.12 OAJ09486.1 - 0.47 9.7 3.9 0.9 8.8 3.9 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ09486.1 - 1.4 7.1 3.2 2 6.6 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 OAJ09486.1 - 4.3 7.2 6.4 0.92 9.4 2.7 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.6 OAJ09486.1 - 4.5 7.7 10.2 7.1 7.1 7.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MBOAT_2 PF13813.6 OAJ09493.1 - 8.5e-10 38.8 3.2 2.2e-07 31.1 3.2 2.8 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family TPR_2 PF07719.17 OAJ09494.1 - 2.4e-29 99.1 13.3 6.7e-05 22.7 0.1 10.1 11 0 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ09494.1 - 2.8e-24 85.1 6.0 5.6e-09 36.1 0.5 5.8 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAJ09494.1 - 4e-21 73.9 9.6 0.00013 21.7 0.1 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ09494.1 - 3.2e-18 64.4 6.7 2.5e-05 24.1 0.1 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ09494.1 - 1.7e-15 57.0 15.5 1.5e-05 25.2 0.2 7.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ09494.1 - 1.9e-13 49.8 0.5 2.1 8.9 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ09494.1 - 7.5e-12 45.7 22.8 0.002 18.7 0.0 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ09494.1 - 5.6e-11 41.9 9.6 0.11 12.2 0.0 8.3 9 1 1 10 10 10 3 TPR repeat TPR_19 PF14559.6 OAJ09494.1 - 6.1e-11 42.7 18.9 0.61 10.6 0.0 8.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ09494.1 - 1.4e-10 41.1 26.9 0.17 12.8 1.0 9.6 6 2 4 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ09494.1 - 1.6e-05 25.2 23.1 1 10.2 0.2 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ09494.1 - 2.1e-05 24.2 12.1 16 5.8 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ09494.1 - 0.0013 18.9 10.4 0.31 11.2 0.2 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ09494.1 - 0.002 18.0 12.1 0.83 9.6 0.3 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ09494.1 - 0.031 13.6 11.2 0.053 12.9 0.5 4.6 5 1 1 6 6 6 0 MalT-like TPR region TPR_21 PF09976.9 OAJ09494.1 - 0.15 11.7 2.1 14 5.4 0.0 4.0 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF3336 PF11815.8 OAJ09497.1 - 1.2e-46 157.8 1.1 2.1e-46 157.0 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAJ09497.1 - 9e-19 68.5 3.0 6.2e-18 65.7 0.2 3.4 3 1 0 3 3 3 1 Patatin-like phospholipase TadE PF07811.12 OAJ09497.1 - 2.9 8.3 9.0 0.27 11.5 3.9 2.0 2 0 0 2 2 2 0 TadE-like protein DDE_Tnp_4 PF13359.6 OAJ09502.1 - 1.7e-31 109.0 0.0 2e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ09502.1 - 5.9e-09 35.9 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ09502.1 - 8.7e-08 32.0 0.0 1.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein KDZ PF18758.1 OAJ09507.1 - 9e-05 22.2 0.5 0.00014 21.6 0.4 1.3 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RVT_1 PF00078.27 OAJ09508.1 - 6.8e-27 94.4 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spt20 PF12090.8 OAJ09508.1 - 0.14 11.7 5.2 0.25 10.9 5.2 1.3 1 0 0 1 1 1 0 Spt20 family Integrase_H2C2 PF17921.1 OAJ09513.1 - 3.9e-19 68.5 0.3 7.7e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ09513.1 - 3.3e-18 65.9 0.0 1.5e-17 63.8 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09513.1 - 2.3e-13 50.2 0.0 4.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09513.1 - 2.6e-11 43.4 0.0 9e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09513.1 - 2.2e-09 37.5 0.5 5.3e-08 33.1 0.0 3.0 4 0 0 4 4 4 1 Integrase core domain Chromo PF00385.24 OAJ09513.1 - 0.00038 20.3 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 OAJ09513.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 OAJ09513.1 - 0.052 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 OAJ09513.1 - 0.44 10.7 1.5 1 9.6 1.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 OAJ09517.1 - 7e-17 61.5 1.0 1.7e-16 60.3 1.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ09517.1 - 0.0024 17.9 0.5 0.004 17.2 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OAJ09517.1 - 0.0047 16.8 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Hydrolase_2 PF07486.12 OAJ09517.1 - 0.023 15.5 0.0 0.064 14.1 0.0 1.7 1 0 0 1 1 1 0 Cell Wall Hydrolase zf-CCHC_3 PF13917.6 OAJ09517.1 - 0.033 14.1 0.7 0.068 13.2 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Ldh_1_N PF00056.23 OAJ09520.1 - 0.0021 18.2 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RVT_2 PF07727.14 OAJ09521.1 - 4e-39 134.7 0.0 5.5e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09521.1 - 1.2e-16 60.9 0.0 2.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09521.1 - 3.5e-05 23.6 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09521.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain RVT_2 PF07727.14 OAJ09522.1 - 2.6e-12 46.9 0.0 4.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ09522.1 - 0.01 15.7 1.4 0.059 13.2 0.8 2.5 2 1 0 2 2 2 0 Reverse transcriptase-like Retrotran_gag_2 PF14223.6 OAJ09523.1 - 6e-09 35.7 0.0 8.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 OAJ09523.1 - 0.012 15.4 1.6 0.019 14.8 1.6 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 OAJ09523.1 - 0.026 14.6 1.0 0.042 13.9 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 OAJ09527.1 - 1.9e-11 44.1 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09527.1 - 4e-05 23.6 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM219A PF15260.6 OAJ09527.1 - 0.091 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM219A Integrase_H2C2 PF17921.1 OAJ09528.1 - 9.5e-16 57.7 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09528.1 - 3.9e-13 49.3 0.1 8.9e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09528.1 - 1.8e-12 47.5 0.0 5.1e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ09528.1 - 5.8e-09 35.8 0.0 8.6e-07 28.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ09528.1 - 0.0006 20.4 1.1 0.0018 18.9 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ09528.1 - 0.012 15.9 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ09528.1 - 0.038 14.6 1.0 0.095 13.3 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ09528.1 - 0.052 13.9 0.1 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OAJ09529.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein ABC_membrane PF00664.23 OAJ09534.1 - 2.7e-58 197.8 28.2 1.7e-32 113.2 14.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ09534.1 - 3e-54 183.3 0.0 6.4e-31 107.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ09534.1 - 2.3e-07 30.5 2.5 0.016 14.6 0.1 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAJ09534.1 - 1.8e-06 28.0 0.6 0.0042 17.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ09534.1 - 2.8e-06 27.8 2.3 0.066 13.6 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ09534.1 - 5.7e-06 26.0 0.2 0.0097 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ09534.1 - 3e-05 24.6 7.0 0.67 10.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 OAJ09534.1 - 5.1e-05 22.9 0.4 0.56 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OAJ09534.1 - 5.8e-05 23.1 0.2 0.28 11.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAJ09534.1 - 8.7e-05 22.5 1.5 0.41 10.4 0.1 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAJ09534.1 - 0.00022 21.5 0.1 0.41 10.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAJ09534.1 - 0.00032 20.2 0.1 1 8.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 OAJ09534.1 - 0.00048 20.3 0.3 0.0015 18.7 0.3 1.9 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 OAJ09534.1 - 0.00068 18.8 0.0 0.031 13.3 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Dynamin_N PF00350.23 OAJ09534.1 - 0.0012 18.9 3.0 0.11 12.6 0.1 3.0 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.12 OAJ09534.1 - 0.0075 15.6 0.7 1 8.6 0.2 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 OAJ09534.1 - 0.0085 15.8 2.3 0.54 9.9 0.1 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 OAJ09534.1 - 0.016 14.8 1.0 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OAJ09534.1 - 0.02 15.1 0.1 6.6 7.0 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 OAJ09534.1 - 0.021 14.8 1.4 5.5 6.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 OAJ09534.1 - 0.031 14.3 0.2 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OAJ09534.1 - 0.036 13.2 0.4 4.4 6.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 OAJ09534.1 - 0.044 13.8 1.3 34 4.5 0.0 4.1 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.22 OAJ09534.1 - 0.085 13.3 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 OAJ09534.1 - 0.089 13.0 1.0 12 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 OAJ09534.1 - 0.096 12.4 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAJ09534.1 - 0.1 11.9 0.6 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 OAJ09534.1 - 0.15 10.9 1.8 0.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 OAJ09534.1 - 0.29 11.6 1.5 27 5.2 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAJ09534.1 - 0.31 11.6 1.0 9.9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain FAR1 PF03101.15 OAJ09539.1 - 6.8e-06 26.7 1.4 1.1e-05 26.1 1.4 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain RPA_interact_C PF14768.6 OAJ09539.1 - 0.12 13.0 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Replication protein A interacting C-terminal 2OG-FeII_Oxy_3 PF13640.6 OAJ09543.1 - 4.6e-08 33.8 0.3 1.3e-07 32.4 0.3 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OAJ09543.1 - 0.012 16.2 0.0 0.034 14.8 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ricin_B_lectin PF00652.22 OAJ09544.1 - 0.048 13.9 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Spin-Ssty PF02513.17 OAJ09544.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Spin/Ssty Family RT_RNaseH PF17917.1 OAJ09549.1 - 1e-12 48.2 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09549.1 - 2.7e-07 30.6 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Transposase_21 PF02992.14 OAJ09554.1 - 0.00027 20.3 0.0 0.00048 19.4 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 zf-RVT PF13966.6 OAJ09558.1 - 7.8e-06 26.5 1.2 1.5e-05 25.6 1.2 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 OAJ09558.1 - 0.0012 19.1 0.1 0.0039 17.4 0.1 1.9 2 0 0 2 2 2 1 RNase H Tryp_inh PF17983.1 OAJ09558.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Trypsin inhibitors 1,2 and 3 Ribosomal_60s PF00428.19 OAJ09558.1 - 8.7 7.0 14.6 3.7 8.2 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RVT_1 PF00078.27 OAJ09559.1 - 6.4e-27 94.5 0.0 9.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ09559.1 - 1.8e-18 66.5 0.2 4.5e-18 65.2 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ09559.1 - 8.5e-07 28.7 2.1 2.4e-06 27.2 2.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RecC_C PF17946.1 OAJ09559.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 RecC C-terminal domain NGF PF00243.18 OAJ09559.1 - 0.38 11.0 1.4 1 9.6 0.4 2.2 2 1 0 2 2 2 0 Nerve growth factor family AhpC-TSA_2 PF13911.6 OAJ09565.1 - 1.3e-12 47.8 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ09565.1 - 1.4e-07 31.4 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ09565.1 - 1.4e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family CDO_I PF05995.12 OAJ09570.1 - 8.5e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAJ09570.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PCO_ADO SMP_2 PF10144.9 OAJ09570.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin FAM60A PF15396.6 OAJ09571.1 - 1.6 8.7 15.8 0.91 9.5 10.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A TFIIA PF03153.13 OAJ09571.1 - 2 8.3 25.4 0.13 12.3 19.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 OAJ09571.1 - 3.9 6.2 7.5 6.1 5.5 7.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 OAJ09571.1 - 6.7 5.6 16.3 0.38 9.7 10.1 1.8 2 0 0 2 2 2 0 Solute carrier family 12 Transposase_21 PF02992.14 OAJ09574.1 - 3.2e-14 52.7 0.1 7.6e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Pox_Ag35 PF03286.14 OAJ09574.1 - 0.03 14.1 4.8 0.065 13.0 4.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GEMIN8 PF15348.6 OAJ09574.1 - 0.049 13.9 2.0 0.11 12.8 2.0 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF4218 PF13960.6 OAJ09574.1 - 0.088 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Plasmodium_Vir PF05795.11 OAJ09574.1 - 0.43 9.9 2.0 0.74 9.2 2.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4551 PF15087.6 OAJ09574.1 - 9.6 4.9 7.5 17 4.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ferric_reduct PF01794.19 OAJ09578.1 - 1.5e-16 60.6 2.5 3.9e-16 59.3 2.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Hexapep PF00132.24 OAJ09578.1 - 0.0014 18.2 2.3 0.015 15.0 2.3 2.3 1 1 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAJ09578.1 - 0.0065 16.8 0.5 0.0065 16.8 0.5 2.6 2 1 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 OAJ09578.1 - 0.18 11.4 0.0 0.69 9.4 0.0 1.8 2 0 0 2 2 2 0 Nucleotidyl transferase AtuA PF07287.11 OAJ09578.1 - 0.22 10.2 1.4 0.38 9.4 1.4 1.3 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA DUF2457 PF10446.9 OAJ09578.1 - 7.4 5.6 7.2 19 4.2 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NAD_binding_6 PF08030.12 OAJ09579.1 - 5.1e-12 46.2 0.0 8.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ09579.1 - 2.7e-07 30.7 0.0 8.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Methyltransf_25 PF13649.6 OAJ09580.1 - 4.3e-11 43.4 0.1 1e-10 42.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ09580.1 - 1.8e-10 40.8 0.2 3.2e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ09580.1 - 1.9e-10 40.7 0.1 3.2e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAJ09580.1 - 1.5e-08 34.7 0.0 4.2e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ09580.1 - 1.3e-07 32.1 0.0 3.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ09580.1 - 4.8e-07 29.4 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAJ09580.1 - 1.3e-05 24.3 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 OAJ09580.1 - 7.9e-05 22.3 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAJ09580.1 - 0.00017 22.2 0.1 0.0004 21.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAJ09580.1 - 0.0017 18.3 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAJ09580.1 - 0.0018 18.4 0.2 0.0031 17.6 0.2 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 OAJ09580.1 - 0.0042 16.9 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OAJ09580.1 - 0.0056 16.4 0.1 0.0088 15.8 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OAJ09580.1 - 0.025 13.9 0.3 0.062 12.6 0.1 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 OAJ09580.1 - 0.031 13.7 0.4 0.1 12.0 0.4 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 OAJ09580.1 - 0.05 13.2 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAJ09580.1 - 0.067 13.2 0.6 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAJ09580.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 EAL PF00563.20 OAJ09584.1 - 2.4e-77 259.7 0.8 8e-77 258.0 0.3 2.2 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 OAJ09584.1 - 1e-50 171.7 0.0 2.1e-50 170.6 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 OAJ09584.1 - 1.8e-37 127.9 0.5 5.6e-22 78.0 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.7 OAJ09584.1 - 6.1e-33 113.2 0.0 1.5e-21 76.6 0.0 4.6 3 1 0 3 3 3 3 PAS domain PAS_8 PF13188.7 OAJ09584.1 - 3.8e-23 81.0 1.0 1.8e-08 34.2 0.1 4.1 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 OAJ09584.1 - 2.3e-21 75.9 0.1 2e-08 34.2 0.0 4.5 3 1 1 4 4 4 3 PAS fold PAS_4 PF08448.10 OAJ09584.1 - 4.9e-20 71.8 2.1 7.1e-08 32.7 0.0 3.8 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 OAJ09584.1 - 9.8e-15 54.6 0.4 2.9e-09 37.1 0.0 3.6 4 0 0 4 4 4 2 PAS fold MEKHLA PF08670.11 OAJ09584.1 - 0.014 15.3 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 MEKHLA domain PAS_7 PF12860.7 OAJ09584.1 - 0.016 15.4 0.1 2.8 8.1 0.0 3.1 2 0 0 2 2 2 0 PAS fold HATPase_c PF02518.26 OAJ09585.1 - 1e-22 80.7 0.0 1.8e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAJ09585.1 - 1.5e-07 31.4 0.1 1.5e-07 31.4 0.1 2.5 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 OAJ09585.1 - 2.3e-06 27.6 0.1 8.2e-06 25.8 0.0 2.1 2 1 1 3 3 3 1 PAS fold PAS_4 PF08448.10 OAJ09585.1 - 4.4e-05 23.7 0.0 0.00074 19.7 0.0 2.7 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OAJ09585.1 - 7.1e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OAJ09585.1 - 0.015 15.3 0.1 0.078 13.0 0.0 2.3 2 0 0 2 2 2 0 PAS domain HATPase_c_3 PF13589.6 OAJ09585.1 - 0.015 15.1 0.0 0.053 13.3 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ecm29 PF13001.7 OAJ09585.1 - 0.065 11.9 0.2 0.091 11.4 0.2 1.1 1 0 0 1 1 1 0 Proteasome stabiliser HATPase_c_5 PF14501.6 OAJ09585.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 GHKL domain HATPase_c PF02518.26 OAJ09586.1 - 8e-27 94.0 0.0 1.8e-26 92.8 0.0 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 OAJ09586.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 OAJ09586.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 OAJ09586.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PilJ PF13675.6 OAJ09586.1 - 0.058 13.4 0.4 0.075 13.1 0.4 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Response_reg PF00072.24 OAJ09587.1 - 1.2e-19 70.5 0.1 1.3e-19 70.4 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain GFO_IDH_MocA PF01408.22 OAJ09587.1 - 0.019 15.8 0.1 0.023 15.5 0.1 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CheX PF13690.6 OAJ09588.1 - 0.0016 18.5 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX DUF2235 PF09994.9 OAJ09597.1 - 1.7e-40 139.2 0.0 3e-40 138.4 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pkinase PF00069.25 OAJ09605.1 - 2.4e-61 207.4 0.0 3.2e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09605.1 - 2.8e-31 108.7 0.0 3.7e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09605.1 - 0.0077 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ09605.1 - 0.076 12.9 0.0 0.28 11.0 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family MitMem_reg PF13012.6 OAJ09606.1 - 8.9e-35 119.5 0.1 1.5e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAJ09606.1 - 1.3e-29 102.6 0.0 2.1e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PQ-loop PF04193.14 OAJ09611.1 - 2.2e-35 120.2 6.3 1.4e-17 63.2 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OAJ09611.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange GyrB_insert PF18053.1 OAJ09611.1 - 0.064 13.1 0.7 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain GATase_7 PF13537.6 OAJ09612.1 - 7.2e-38 129.3 0.0 1.1e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 OAJ09612.1 - 1.3e-37 130.3 0.1 2e-37 129.7 0.1 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 OAJ09612.1 - 3e-29 101.9 0.0 1e-28 100.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAJ09612.1 - 9.7e-06 25.2 0.0 5.2e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 Aluminium induced protein NAD_synthase PF02540.17 OAJ09612.1 - 0.052 12.7 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 OAJ09612.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC RVT_1 PF00078.27 OAJ09616.1 - 8.5e-24 84.3 0.0 1.5e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09616.1 - 1.2e-22 79.8 0.3 1.6e-15 56.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09616.1 - 3e-17 62.8 0.0 3.5e-10 40.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09616.1 - 1.6e-15 56.9 0.1 2.9e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09616.1 - 9e-10 38.8 0.0 2.9e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09616.1 - 4.8e-05 23.9 0.0 0.00017 22.1 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09616.1 - 0.0046 17.5 0.0 0.012 16.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ09616.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger PIF1 PF05970.14 OAJ09618.1 - 5.6e-14 52.1 0.6 5.3e-06 25.8 0.1 3.1 3 1 1 4 4 4 2 PIF1-like helicase AAA_30 PF13604.6 OAJ09618.1 - 2.2e-10 40.6 4.9 7.3e-10 38.9 0.7 3.4 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ09618.1 - 1.9e-05 25.0 2.1 0.00024 21.4 1.8 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ09618.1 - 0.00026 21.4 1.4 0.00054 20.4 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 OAJ09618.1 - 0.012 15.4 0.0 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAJ09618.1 - 0.053 13.2 0.1 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.11 OAJ09618.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Torsin AAA_22 PF13401.6 OAJ09618.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAJ09618.1 - 0.063 13.7 0.3 0.42 11.0 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ09618.1 - 0.11 12.5 0.2 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Helitron_like_N PF14214.6 OAJ09619.1 - 5.5e-24 85.4 0.0 1.4e-23 84.1 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.19 OAJ09625.1 - 2.5e-19 69.6 0.3 5.7e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ09625.1 - 2.5e-09 37.0 0.2 1e-07 31.9 0.0 3.0 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Glyco_transf_24 PF18404.1 OAJ09632.1 - 1.2e-142 474.1 1.9 1.8e-142 473.5 1.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAJ09632.1 - 4.6e-48 164.4 0.1 2.5e-46 158.7 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAJ09632.1 - 2.4e-35 120.9 0.0 4.4e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 OAJ09632.1 - 2.4e-34 118.9 0.0 1.3e-33 116.5 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OAJ09632.1 - 4e-33 115.1 0.0 9.4e-29 100.9 0.0 3.7 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAJ09632.1 - 8.3e-28 97.0 0.0 2.5e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OAJ09632.1 - 1.6e-05 24.6 0.1 3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 PspA_IM30 PF04012.12 OAJ09632.1 - 0.19 11.3 2.4 0.41 10.2 0.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family DBD_Tnp_Mut PF03108.15 OAJ09637.1 - 6.1e-08 32.5 1.2 1.2e-07 31.6 0.3 1.8 2 0 0 2 2 2 1 MuDR family transposase WH1 PF00568.23 OAJ09637.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain DDE_3 PF13358.6 OAJ09642.1 - 6.4e-33 113.6 0.0 1.2e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ09642.1 - 0.0026 18.3 0.0 0.0084 16.7 0.0 1.9 1 1 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OAJ09642.1 - 0.0049 17.1 0.0 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.6 OAJ09642.1 - 0.0099 15.5 0.1 0.029 14.0 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.11 OAJ09642.1 - 0.11 11.4 0.1 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain TIP49 PF06068.13 OAJ09644.1 - 3.4e-156 519.8 0.0 5.4e-156 519.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ09644.1 - 2.8e-21 75.4 0.1 7.7e-21 74.0 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OAJ09644.1 - 2.2e-10 41.1 0.1 4.1e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ09644.1 - 5.5e-09 36.0 0.1 1.7e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ09644.1 - 1.5e-07 31.8 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ09644.1 - 5.3e-05 23.2 0.2 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OAJ09644.1 - 0.00017 22.0 0.5 0.068 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ09644.1 - 0.00029 21.3 0.1 0.0025 18.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OAJ09644.1 - 0.00038 20.7 0.1 0.00073 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ09644.1 - 0.0038 16.6 0.1 0.29 10.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ09644.1 - 0.0099 16.1 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAJ09644.1 - 0.011 15.3 0.3 0.011 15.3 0.3 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OAJ09644.1 - 0.018 14.7 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ09644.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 OAJ09644.1 - 0.028 14.2 0.1 0.092 12.5 0.1 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAJ09644.1 - 0.04 13.4 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OAJ09644.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OAJ09644.1 - 0.073 12.8 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAJ09644.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 OAJ09647.1 - 7e-45 152.9 0.1 1.2e-44 152.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ09647.1 - 6.2e-24 84.5 0.0 4.6e-23 81.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ09647.1 - 2e-18 66.4 0.3 2e-18 66.4 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 OAJ09647.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OAJ09647.1 - 0.0025 17.9 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 OAJ09648.1 - 1e-16 60.8 33.1 1.1e-08 35.1 10.1 2.5 3 0 0 3 3 3 2 AN1-like Zinc finger QWRF PF04484.12 OAJ09648.1 - 0.61 9.8 7.2 0.9 9.2 7.2 1.3 1 0 0 1 1 1 0 QWRF family UcrQ PF02939.16 OAJ09654.1 - 4e-26 90.8 4.1 4.9e-26 90.5 4.1 1.1 1 0 0 1 1 1 1 UcrQ family UQ_con PF00179.26 OAJ09656.1 - 2.3e-22 79.1 0.0 2.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dimer_Tnp_hAT PF05699.14 OAJ09661.1 - 3.2e-14 52.5 0.1 6.9e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CorA PF01544.18 OAJ09661.1 - 0.12 11.6 2.3 0.24 10.7 2.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 OAJ09662.1 - 2.1e-38 132.2 0.0 3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09662.1 - 5.3e-16 58.7 0.0 8.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09662.1 - 7.8e-06 25.4 0.0 1.6e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OAJ09667.1 - 6.3e-68 229.0 0.0 7.5e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09667.1 - 2.7e-33 115.3 0.0 3.5e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09667.1 - 0.0028 17.0 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ09667.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ09667.1 - 0.32 10.9 3.9 0.32 10.9 1.6 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family LapA_dom PF06305.11 OAJ09668.1 - 0.021 14.6 0.8 0.044 13.6 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NOA36 PF06524.12 OAJ09668.1 - 0.58 9.4 5.0 1.2 8.4 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein FAD_binding_4 PF01565.23 OAJ09673.1 - 2.9e-23 82.2 1.8 1.1e-22 80.3 1.5 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ09673.1 - 0.0052 16.9 0.2 0.01 15.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like CMS1 PF14617.6 OAJ09674.1 - 1.7e-18 66.9 3.4 9.1e-07 28.5 0.0 4.2 2 2 1 3 3 3 3 U3-containing 90S pre-ribosomal complex subunit DUF4504 PF14953.6 OAJ09675.1 - 1e-05 25.1 0.0 0.0035 16.8 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) Sec7 PF01369.20 OAJ09680.1 - 6.1e-29 101.0 0.0 9.6e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAJ09680.1 - 8.3e-08 32.7 0.4 7.1e-07 29.7 0.1 2.4 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 OAJ09680.1 - 0.0035 17.7 0.6 0.012 16.0 0.3 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3090 PF11290.8 OAJ09681.1 - 0.17 11.7 1.8 1.5 8.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) eIF2A PF08662.11 OAJ09687.1 - 4.3e-39 134.4 0.4 1.7e-34 119.4 0.0 4.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OAJ09687.1 - 1.1e-06 28.9 0.2 48 4.3 0.0 7.3 5 3 2 8 8 8 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 OAJ09687.1 - 3.7e-06 26.7 0.1 8e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 OAJ09687.1 - 0.0057 17.5 3.1 1.6 9.8 0.0 5.2 5 1 1 6 6 6 1 WD domain, G-beta repeat DPPIV_N PF00930.21 OAJ09687.1 - 0.029 13.1 0.1 3.3 6.4 0.0 3.3 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Sad1_UNC PF07738.13 OAJ09693.1 - 7.7e-12 45.4 0.0 6.3e-05 23.0 0.0 3.1 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal TFIIA PF03153.13 OAJ09693.1 - 0.047 13.7 3.6 0.017 15.2 0.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HrpB7 PF09486.10 OAJ09693.1 - 0.06 13.7 5.8 0.21 12.0 0.9 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GrpE PF01025.19 OAJ09693.1 - 0.088 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 GrpE BOP1NT PF08145.12 OAJ09694.1 - 4e-106 354.7 1.9 6.2e-106 354.1 1.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAJ09694.1 - 1.9e-20 72.8 2.4 5e-06 27.2 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09694.1 - 0.0017 18.6 0.0 2.2 8.6 0.0 4.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 OAJ09694.1 - 0.23 10.7 16.5 0.39 10.0 16.5 1.3 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 OAJ09694.1 - 1.8 8.6 16.5 3.9 7.5 16.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 OAJ09694.1 - 3.2 5.9 21.1 4.5 5.4 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.19 OAJ09695.1 - 5.6e-29 101.0 0.0 1.9e-28 99.2 0.0 1.7 1 1 0 1 1 1 1 Actin ALP_N PF17989.1 OAJ09695.1 - 0.055 13.7 0.0 0.25 11.5 0.0 1.8 1 1 0 1 1 1 0 Actin like proteins N terminal domain ABC_membrane PF00664.23 OAJ09698.1 - 3.6e-11 43.2 1.6 1.3e-10 41.4 1.6 1.9 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ09700.1 - 6.2e-30 104.5 0.0 9.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAJ09700.1 - 2.4e-19 70.1 12.2 7.4e-10 38.9 2.0 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ09700.1 - 4.5e-08 32.8 0.6 7.5e-06 25.5 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ09700.1 - 0.0003 20.7 0.2 0.39 10.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAJ09700.1 - 0.0003 21.1 0.2 0.0013 19.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 OAJ09700.1 - 0.00063 19.9 0.5 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 OAJ09700.1 - 0.0019 18.0 0.2 0.012 15.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ09700.1 - 0.0019 18.6 1.6 0.0048 17.3 0.8 2.0 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAJ09700.1 - 0.0046 16.3 0.4 0.013 14.9 0.1 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 OAJ09700.1 - 0.013 15.2 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 OAJ09700.1 - 0.015 15.1 0.2 0.04 13.7 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 OAJ09700.1 - 0.023 15.2 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OAJ09700.1 - 0.033 13.1 0.1 0.068 12.1 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain O-antigen_lig PF13425.6 OAJ09700.1 - 0.086 11.6 7.0 0.14 10.9 7.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein NTPase_1 PF03266.15 OAJ09700.1 - 0.093 12.6 0.3 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 OAJ09700.1 - 0.2 12.2 0.0 0.39 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ09701.1 - 2.6e-13 50.7 0.0 5.7e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 OAJ09701.1 - 0.0095 16.0 0.2 0.029 14.4 0.0 2.0 2 1 0 2 2 2 1 Dynamin family ANAPC_CDC26 PF10471.9 OAJ09701.1 - 0.98 10.3 5.4 0.49 11.3 2.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 MTHFR PF02219.17 OAJ09705.1 - 8.4e-94 314.1 0.0 8.8e-84 281.2 0.0 3.3 3 0 0 3 3 3 3 Methylenetetrahydrofolate reductase Cytochrom_B561 PF03188.16 OAJ09705.1 - 5.6e-09 36.3 12.3 1e-08 35.4 12.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 OAJ09705.1 - 9.8 6.3 15.8 32 4.7 15.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) ECH_1 PF00378.20 OAJ09706.1 - 1.8e-17 63.5 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ09706.1 - 2.4e-06 27.3 0.1 2.9e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_C48 PF02902.19 OAJ09710.1 - 1.6e-12 47.8 0.1 1.6e-12 47.8 0.1 2.1 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 OAJ09710.1 - 0.065 12.9 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 SWIM zinc finger DUF5352 PF17303.2 OAJ09710.1 - 0.076 12.9 2.9 0.077 12.8 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5352) CMS1 PF14617.6 OAJ09710.1 - 0.77 9.0 5.1 0.67 9.2 3.5 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pkinase PF00069.25 OAJ09715.1 - 4.4e-62 209.8 0.0 1.3e-61 208.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09715.1 - 2.1e-34 119.0 0.0 6.3e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09715.1 - 8.1e-06 25.3 0.0 0.0023 17.3 0.0 3.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 OAJ09715.1 - 0.00095 19.1 0.0 0.0083 16.1 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ09715.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Palm_thioest PF02089.15 OAJ09716.1 - 5.5e-76 255.6 0.0 7e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAJ09716.1 - 0.048 13.3 0.1 0.14 11.7 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Helitron_like_N PF14214.6 OAJ09722.1 - 6.6e-40 137.4 0.0 1.2e-39 136.5 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Asp_protease_2 PF13650.6 OAJ09725.1 - 0.00059 20.4 0.0 0.0016 19.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09725.1 - 0.0056 17.2 0.0 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ09725.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 OAJ09726.1 - 4.2e-23 81.3 0.1 9.5e-14 51.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09726.1 - 1.4e-18 67.1 0.0 3.4e-12 46.6 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09726.1 - 2.6e-17 63.1 0.0 5.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09726.1 - 1.8e-15 56.8 0.0 3.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09726.1 - 3e-10 40.3 0.0 7.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 OAJ09726.1 - 6.6e-07 29.2 0.0 1e-05 25.3 0.0 2.5 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDC10_II PF16787.5 OAJ09731.1 - 2.2e-43 148.5 0.0 3.8e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_28 PF13518.6 OAJ09731.1 - 0.015 15.4 0.6 0.16 12.2 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 OAJ09731.1 - 0.045 14.1 0.1 0.83 10.0 0.0 2.7 2 0 0 2 2 2 0 Transposase BH4 PF02180.17 OAJ09732.1 - 0.23 11.3 0.4 0.39 10.6 0.4 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 RVT_1 PF00078.27 OAJ09739.1 - 6.1e-28 97.8 0.0 4.3e-27 95.1 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mso1_C PF14477.6 OAJ09739.1 - 1.4 9.4 8.7 11 6.5 0.1 4.0 3 0 0 3 3 3 0 Membrane-polarising domain of Mso1 Pkinase PF00069.25 OAJ09744.1 - 3.1e-44 151.3 0.0 5.3e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09744.1 - 2.8e-25 89.1 0.0 5.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ09744.1 - 0.00014 21.3 0.1 0.00041 19.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ09744.1 - 0.00097 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Phage_GP20 PF06810.11 OAJ09744.1 - 0.0029 17.4 0.4 0.0029 17.4 0.4 2.3 2 0 0 2 2 2 1 Phage minor structural protein GP20 Filament PF00038.21 OAJ09744.1 - 0.0064 16.1 13.4 0.0064 16.1 13.4 2.2 1 1 1 2 2 2 1 Intermediate filament protein Bcr-Abl_Oligo PF09036.10 OAJ09744.1 - 0.051 13.6 0.7 0.21 11.6 0.7 2.1 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain KLRAQ PF10205.9 OAJ09744.1 - 0.057 13.7 11.8 1.1 9.5 5.5 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein TcdB_N PF12918.7 OAJ09744.1 - 0.062 13.6 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain PhoU PF01895.19 OAJ09744.1 - 0.1 13.1 6.5 1.3 9.6 0.8 2.8 2 1 1 3 3 3 0 PhoU domain RIO1 PF01163.22 OAJ09744.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 RIO1 family MAD PF05557.13 OAJ09744.1 - 0.17 10.2 23.1 0.25 9.7 23.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Sec8_exocyst PF04048.14 OAJ09744.1 - 0.22 11.4 7.3 1 9.2 0.2 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ATG16 PF08614.11 OAJ09744.1 - 0.38 11.0 28.7 0.27 11.4 6.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 OAJ09744.1 - 0.4 11.0 23.8 1.4 9.3 1.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3958 PF13125.6 OAJ09744.1 - 1.4 9.2 22.5 0.18 12.0 12.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) TMF_DNA_bd PF12329.8 OAJ09744.1 - 3.3 7.8 19.8 0.55 10.3 0.6 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 OAJ09744.1 - 3.7 6.9 26.5 26 4.2 26.5 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Tup_N PF08581.10 OAJ09744.1 - 3.9 7.8 16.3 3.2 8.1 6.6 3.3 2 1 1 3 3 3 0 Tup N-terminal HemX PF04375.14 OAJ09744.1 - 5.9 6.1 22.3 84 2.3 22.3 2.2 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF5595 PF18077.1 OAJ09744.1 - 6.6 6.9 7.9 1.4 9.0 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) KELK PF15796.5 OAJ09744.1 - 9.1 6.8 21.3 0.3 11.6 12.0 2.8 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KDZ PF18758.1 OAJ09757.1 - 9.1e-51 172.6 0.0 4.5e-50 170.3 0.0 2.1 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ09757.1 - 2.6e-08 34.0 0.2 6.5e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ09757.1 - 2.3e-07 30.9 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases BAR_3 PF16746.5 OAJ09757.1 - 0.0026 17.5 3.3 0.16 11.6 0.0 3.1 3 0 0 3 3 3 1 BAR domain of APPL family Perilipin PF03036.16 OAJ09757.1 - 0.51 9.3 10.4 0.62 9.0 0.6 2.2 2 0 0 2 2 2 0 Perilipin family zf-BED PF02892.15 OAJ09760.1 - 0.00072 19.5 1.3 0.0018 18.2 1.3 1.6 1 0 0 1 1 1 1 BED zinc finger NDC10_II PF16787.5 OAJ09766.1 - 2.2e-40 138.7 0.0 3.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Ecl1 PF12855.7 OAJ09773.1 - 2.6e-05 25.5 7.2 2.6e-05 25.5 7.2 7.4 2 1 2 5 5 5 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 OAJ09773.1 - 0.00041 20.4 1.5 0.0011 19.0 1.5 1.7 1 0 0 1 1 1 1 MYND finger Dicty_REP PF05086.12 OAJ09773.1 - 2.2 6.1 5.3 4 5.3 5.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Androgen_recep PF02166.16 OAJ09774.1 - 0.029 13.2 2.7 0.033 13.0 2.7 1.1 1 0 0 1 1 1 0 Androgen receptor Hydin_ADK PF17213.3 OAJ09774.1 - 0.032 14.5 1.0 0.038 14.3 1.0 1.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain KOW PF00467.29 OAJ09778.1 - 0.011 15.7 0.3 0.019 14.9 0.3 1.4 1 0 0 1 1 1 0 KOW motif CTD PF12815.7 OAJ09778.1 - 0.087 13.4 13.0 6.1 7.5 13.0 2.5 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 UCH PF00443.29 OAJ09779.1 - 1.1e-75 254.5 0.0 1.5e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OAJ09779.1 - 2.1e-14 53.9 0.0 1.4e-13 51.3 0.0 2.4 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 OAJ09779.1 - 1.9e-13 50.7 0.0 9e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OAJ09779.1 - 9.1e-05 22.3 0.0 0.095 12.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal CW_binding_1 PF01473.20 OAJ09779.1 - 0.15 12.4 1.9 0.38 11.2 0.9 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat zf-FPG_IleRS PF06827.14 OAJ09779.1 - 0.22 11.4 1.1 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS RVT_2 PF07727.14 OAJ09785.1 - 2e-59 201.2 0.1 3e-59 200.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09785.1 - 3.3e-21 75.7 0.0 3.2e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OAJ09785.1 - 0.00019 21.1 0.1 0.00083 19.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 OAJ09785.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 OAJ09785.1 - 0.13 12.7 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain gag_pre-integrs PF13976.6 OAJ09786.1 - 0.00037 20.3 1.5 0.00073 19.3 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain CPSF_A PF03178.15 OAJ09798.1 - 5.8e-43 147.4 0.0 9.3e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAJ09798.1 - 5.5e-22 78.1 0.0 2.5e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CSTF2_hinge PF14327.6 OAJ09799.1 - 2.8e-30 104.6 5.7 2.8e-30 104.6 5.7 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAJ09799.1 - 3.1e-22 78.2 0.1 4.7e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OAJ09799.1 - 7.2e-17 60.7 2.6 7.2e-17 60.7 2.6 3.1 3 0 0 3 3 3 2 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 OAJ09799.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Pkinase PF00069.25 OAJ09805.1 - 2.4e-49 168.1 5.4 2.4e-49 168.1 0.0 3.3 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09805.1 - 9.5e-22 77.5 0.0 9.5e-22 77.5 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase TFIIA PF03153.13 OAJ09806.1 - 0.0063 16.6 12.3 0.0081 16.2 12.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 OAJ09806.1 - 0.19 10.7 15.1 0.26 10.2 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GAPT PF11770.8 OAJ09806.1 - 0.4 10.5 0.1 0.4 10.5 0.1 1.7 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Spt20 PF12090.8 OAJ09806.1 - 0.76 9.3 23.0 1.1 8.8 23.0 1.2 1 0 0 1 1 1 0 Spt20 family Ctf8 PF09696.10 OAJ09812.1 - 2.2e-07 31.3 1.3 2.3e-05 24.8 1.3 2.2 1 1 0 1 1 1 1 Ctf8 zf-CCCH PF00642.24 OAJ09813.1 - 2e-17 62.6 14.4 1.6e-10 40.6 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ09813.1 - 5.1e-07 29.5 14.3 3.3e-06 26.9 3.7 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ09813.1 - 0.00074 19.3 1.2 0.00074 19.3 1.2 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAJ09813.1 - 0.15 12.6 0.2 0.15 12.6 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OAJ09813.1 - 2.5 8.9 10.4 9.3 7.0 1.7 2.4 1 1 1 2 2 2 0 Torus domain p450 PF00067.22 OAJ09819.1 - 6.7e-59 199.8 0.0 1.3e-58 198.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PIF1 PF05970.14 OAJ09826.1 - 9.1e-15 54.7 0.0 1.1e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ09826.1 - 5.5e-05 23.0 0.1 6.7e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ09826.1 - 0.002 18.5 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OAJ09826.1 - 0.012 14.7 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 OAJ09826.1 - 0.084 12.9 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helitron_like_N PF14214.6 OAJ09827.1 - 3e-30 105.9 0.1 5.2e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus CIA30 PF08547.12 OAJ09840.1 - 0.0083 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PH_12 PF16457.5 OAJ09840.1 - 0.06 13.9 0.2 0.089 13.3 0.2 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain IMUP PF15761.5 OAJ09840.1 - 0.58 10.9 7.4 0.97 10.2 7.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Syntaphilin PF15290.6 OAJ09840.1 - 5.3 6.6 5.6 7 6.2 5.6 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Tim44 PF04280.15 OAJ09841.1 - 4.1e-16 59.4 1.6 6.3e-13 49.1 0.0 2.9 3 0 0 3 3 3 2 Tim44-like domain FYDLN_acid PF09538.10 OAJ09841.1 - 0.12 13.1 19.1 0.31 11.8 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.10 OAJ09841.1 - 1.4 9.2 21.2 0.62 10.4 1.6 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.6 OAJ09841.1 - 2.7 7.9 20.3 1.9 8.4 1.2 3.4 3 0 0 3 3 3 0 Spore coat protein CotO SpoIIIAH PF12685.7 OAJ09841.1 - 5 6.9 26.4 2.1 8.1 3.7 3.3 3 0 0 3 3 3 0 SpoIIIAH-like protein NST1 PF13945.6 OAJ09841.1 - 5.7 7.0 19.7 0.44 10.6 2.8 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator CIA30 PF08547.12 OAJ09842.1 - 0.029 14.4 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Seipin PF06775.14 OAJ09846.1 - 5.4e-41 140.9 0.0 2.8e-40 138.6 0.0 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) tRNA-synt_His PF13393.6 OAJ09847.1 - 7.6e-36 123.9 1.2 2.8e-31 109.0 0.0 2.8 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OAJ09847.1 - 4e-08 33.3 0.0 8.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 OAJ09847.1 - 5.8e-06 26.4 2.0 5.8e-06 26.4 2.0 2.6 2 0 0 2 2 2 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 OAJ09847.1 - 0.00064 19.3 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OAJ09847.1 - 0.082 12.0 0.8 0.81 8.7 0.4 2.3 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) DUF4220 PF13968.6 OAJ09852.1 - 0.22 10.9 1.0 0.32 10.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4471 PF14740.6 OAJ09852.1 - 2.2 7.4 13.2 5.7 6.1 13.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Exonuc_VII_L PF02601.15 OAJ09852.1 - 2.8 7.4 20.7 5.8 6.4 20.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Proteasome PF00227.26 OAJ09853.1 - 4.3e-51 173.1 0.0 5.5e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ09853.1 - 3.2e-11 42.7 0.1 5.5e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.27 OAJ09854.1 - 7.2e-62 205.3 4.0 4.1e-21 74.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein MGS PF02142.22 OAJ09855.1 - 0.006 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain RVT_1 PF00078.27 OAJ09866.1 - 2.9e-08 33.5 0.0 6.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ09866.1 - 1.5e-05 25.5 0.0 5.1e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 OAJ09866.1 - 7.2e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 OAJ09866.1 - 9.4e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09866.1 - 0.00019 22.0 0.0 0.0005 20.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OAJ09866.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 OAJ09866.1 - 0.0012 18.7 0.0 0.0046 16.8 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PSI_integrin PF17205.3 OAJ09866.1 - 0.088 12.6 0.4 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 Integrin plexin domain RVP PF00077.20 OAJ09866.1 - 0.15 12.4 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease CENP-F_leu_zip PF10473.9 OAJ09867.1 - 5.8e-05 23.1 1.3 9.5e-05 22.4 1.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlbD_coat PF14071.6 OAJ09867.1 - 0.0059 16.9 0.3 0.12 12.6 0.1 2.2 2 0 0 2 2 2 1 Putative coat protein Leu_zip PF15294.6 OAJ09867.1 - 0.026 14.1 0.5 0.035 13.6 0.5 1.2 1 0 0 1 1 1 0 Leucine zipper Retrotran_gag_2 PF14223.6 OAJ09871.1 - 3.4e-05 23.5 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ09871.1 - 0.067 13.3 4.1 0.11 12.6 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ09871.1 - 0.67 9.8 4.0 1.1 9.2 4.0 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 OAJ09872.1 - 4e-51 174.0 0.0 6.7e-44 150.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09872.1 - 2e-22 79.6 0.0 6.2e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09872.1 - 3.9e-06 26.6 0.0 8.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09872.1 - 1.7e-05 24.5 0.1 5.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Amino_oxidase PF01593.24 OAJ09875.1 - 2e-49 169.1 0.0 2.5e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ09875.1 - 3.1e-11 43.3 0.5 7.6e-11 42.1 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAJ09875.1 - 2.7e-06 26.4 2.4 0.004 15.9 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAJ09875.1 - 2.8e-06 27.2 2.9 8.3e-06 25.6 2.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ09875.1 - 2.9e-05 23.3 1.1 4.5e-05 22.7 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ09875.1 - 0.00033 20.0 0.8 0.057 12.7 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ09875.1 - 0.00038 19.8 0.2 0.0006 19.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAJ09875.1 - 0.00068 20.1 0.7 0.011 16.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ09875.1 - 0.0016 17.7 1.6 0.021 14.1 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ09875.1 - 0.0058 15.9 0.7 0.01 15.1 0.7 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAJ09875.1 - 0.0079 15.3 0.2 2.8 6.9 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAJ09875.1 - 0.013 15.5 1.5 0.72 9.8 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAJ09875.1 - 0.027 13.8 0.6 0.04 13.3 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAJ09875.1 - 0.049 12.9 0.5 0.076 12.3 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_B PF00136.21 OAJ09876.1 - 1.9e-151 504.9 1.5 3.3e-151 504.1 1.5 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAJ09876.1 - 2.1e-86 290.1 0.0 3.8e-86 289.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAJ09876.1 - 5e-17 62.1 7.2 1.1e-16 61.0 7.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 OAJ09876.1 - 0.0015 18.2 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 OAJ09876.1 - 0.0022 17.0 0.6 0.0065 15.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 OAJ09876.1 - 0.045 13.8 0.1 0.22 11.5 0.1 2.3 1 1 0 1 1 1 0 RNase_H superfamily HTH_DeoR PF08220.12 OAJ09888.1 - 0.0049 16.6 0.0 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain CKS PF01111.19 OAJ09888.1 - 0.092 13.0 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit Complex1_49kDa PF00346.19 OAJ09889.1 - 0.099 11.7 0.1 0.71 8.9 0.1 2.0 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF4413 PF14372.6 OAJ09889.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) zf-MYND PF01753.18 OAJ09890.1 - 0.006 16.6 2.4 0.012 15.7 2.4 1.5 1 0 0 1 1 1 1 MYND finger U3_snoRNA_assoc PF08297.11 OAJ09890.1 - 0.33 11.7 6.7 1 10.1 2.4 2.7 2 0 0 2 2 2 0 U3 snoRNA associated Pkinase PF00069.25 OAJ09891.1 - 4.5e-37 127.8 0.0 5.2e-28 98.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09891.1 - 2.7e-16 59.7 0.0 6.5e-15 55.1 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09891.1 - 7.1e-05 22.3 0.1 0.00059 19.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like RAP1 PF07218.11 OAJ09891.1 - 0.086 11.1 0.3 0.14 10.4 0.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Dimer_Tnp_hAT PF05699.14 OAJ09892.1 - 1.1e-19 70.0 0.3 1.6e-19 69.5 0.3 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region dCMP_cyt_deam_1 PF00383.23 OAJ09898.1 - 2e-20 72.5 0.0 3.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ09898.1 - 7.3e-19 67.9 0.1 9e-18 64.3 0.1 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAJ09898.1 - 2.1e-06 27.8 0.0 3.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 OAJ09898.1 - 0.21 11.7 0.1 0.65 10.1 0.1 1.8 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 EMP24_GP25L PF01105.24 OAJ09899.1 - 1.9e-33 115.9 0.0 2.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD VASt PF16016.5 OAJ09900.1 - 3.1e-37 128.4 0.8 8.1e-37 127.0 0.2 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAJ09900.1 - 1.1e-26 93.0 0.1 6.2e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 GRAM domain ACC_epsilon PF13822.6 OAJ09904.1 - 0.7 10.6 4.1 3.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Mito_carr PF00153.27 OAJ09912.1 - 8.2e-07 28.9 1.1 0.0045 16.9 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein NAD_binding_5 PF07994.12 OAJ09920.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Asn_synthase PF00733.21 OAJ09921.1 - 1e-17 64.8 0.1 1.4e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 OAJ09921.1 - 0.015 15.5 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 OAJ09921.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 OAJ09921.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Ashwin PF15323.6 OAJ09922.1 - 0.13 12.3 3.2 0.25 11.3 3.2 1.5 1 0 0 1 1 1 0 Developmental protein Pox_Ag35 PF03286.14 OAJ09922.1 - 1.1 9.0 8.8 0.13 12.1 4.3 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ribosomal_S15 PF00312.22 OAJ09928.1 - 1.4e-23 82.9 0.1 1.4e-23 82.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_L3 PF00297.22 OAJ09929.1 - 4e-17 62.3 1.2 1.1e-16 60.8 1.0 1.8 1 1 2 3 3 3 1 Ribosomal protein L3 Muskelin_N PF06588.11 OAJ09931.1 - 1.9e-41 142.2 0.1 1.2e-32 113.4 0.0 2.1 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_5 PF13854.6 OAJ09931.1 - 7.2e-12 45.0 1.7 0.00056 19.8 0.0 6.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OAJ09931.1 - 4.2e-10 39.5 5.0 0.046 14.0 0.1 6.6 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 OAJ09931.1 - 1.1e-09 37.7 7.9 1.7e-05 24.3 0.5 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OAJ09931.1 - 1.7e-09 37.8 21.5 5.7e-05 23.3 0.5 7.7 7 2 0 7 7 7 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OAJ09931.1 - 0.00035 20.5 14.0 0.0091 16.0 0.1 6.5 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ09931.1 - 0.00047 20.0 5.7 0.085 12.9 0.1 4.8 5 0 0 5 5 5 2 Kelch motif tRNA_int_endo PF01974.17 OAJ09932.1 - 1.8e-14 53.5 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Polysacc_deac_1 PF01522.21 OAJ09933.1 - 0.002 18.0 0.1 0.0059 16.5 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase RT_RNaseH PF17917.1 OAJ09937.1 - 1.7e-29 102.2 0.0 4.5e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09937.1 - 5.1e-20 71.4 0.0 1.2e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09937.1 - 1e-15 57.5 0.0 2.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ09937.1 - 2.5e-15 56.6 0.1 4.7e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09937.1 - 3.5e-11 43.3 0.0 8.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 OAJ09937.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ09937.1 - 0.00012 22.0 1.6 0.00022 21.1 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 OAJ09937.1 - 0.00054 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09937.1 - 0.00056 20.4 0.0 0.0019 18.7 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 OAJ09937.1 - 0.0008 19.3 0.1 0.0023 17.8 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 OAJ09937.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_6 PF15288.6 OAJ09937.1 - 0.013 15.3 0.8 0.047 13.5 0.8 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ09937.1 - 0.021 14.8 0.1 0.052 13.5 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 OAJ09937.1 - 0.089 13.1 0.2 0.43 10.9 0.0 2.3 2 0 0 2 2 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 OAJ09937.1 - 0.12 12.2 2.1 0.24 11.3 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PHY PF00360.20 OAJ09939.1 - 5.8e-26 90.9 0.0 1.4e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 OAJ09939.1 - 5.1e-17 62.4 0.1 1.7e-16 60.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 OAJ09939.1 - 2.7e-11 44.2 0.0 1.1e-10 42.2 0.0 2.1 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 OAJ09939.1 - 3e-11 43.2 1.1 6.7e-11 42.1 1.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 OAJ09939.1 - 2.3e-10 41.1 0.0 5.8e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 OAJ09939.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 OAJ09939.1 - 1.2 9.0 23.7 0.38 10.7 20.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Response_reg PF00072.24 OAJ09940.1 - 1.7e-16 60.4 0.0 2.7e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 Response regulator receiver domain RcpC PF16976.5 OAJ09940.1 - 0.055 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB Myb_DNA-bind_3 PF12776.7 OAJ09945.1 - 1.9e-14 54.4 0.7 3.1e-14 53.7 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ09945.1 - 3.1e-05 24.3 1.2 0.00018 21.8 1.2 2.1 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 OAJ09946.1 - 1.2e-18 67.3 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ09946.1 - 2e-05 24.3 0.0 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ09946.1 - 0.00011 21.9 0.0 0.011 15.4 0.0 2.1 1 1 1 2 2 2 2 Transposase DDE domain Pkinase PF00069.25 OAJ09952.1 - 2.2e-49 168.2 0.0 3.6e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09952.1 - 2.2e-23 82.9 0.0 4.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ09952.1 - 0.0081 15.0 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OAJ09952.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPL5 PF18168.1 OAJ09952.1 - 0.78 9.0 5.4 1.3 8.3 5.4 1.3 1 0 0 1 1 1 0 Prim-pol family 5 YuzL PF14115.6 OAJ09953.1 - 0.42 11.1 3.3 1.3 9.6 3.3 1.8 1 0 0 1 1 1 0 YuzL-like protein CPSase_L_D2 PF02786.17 OAJ09956.1 - 1.1e-64 217.9 0.0 1.2e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OAJ09956.1 - 1.6e-07 31.1 0.0 1.8e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAJ09956.1 - 0.0001 21.9 0.0 0.00037 20.1 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAJ09956.1 - 0.00033 20.7 0.0 0.00044 20.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 OAJ09956.1 - 0.003 17.0 0.2 0.005 16.3 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAJ09956.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon PGM1_C PF18105.1 OAJ09957.1 - 0.13 11.9 0.3 0.32 10.6 0.0 1.9 3 0 0 3 3 3 0 PGM1 C-terminal domain BLM10_mid PF16507.5 OAJ09969.1 - 5.6e-157 523.6 0.0 7.9e-157 523.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region SDA1 PF05285.12 OAJ09969.1 - 0.86 9.0 11.6 1.4 8.2 11.6 1.2 1 0 0 1 1 1 0 SDA1 DUF4708 PF15813.5 OAJ09974.1 - 0.055 12.6 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) Pterin_bind PF00809.22 OAJ09982.1 - 2.1e-58 197.9 1.6 1.4e-50 172.3 0.3 3.1 2 2 0 2 2 2 2 Pterin binding enzyme HPPK PF01288.20 OAJ09982.1 - 5.1e-28 97.8 0.0 1.4e-27 96.4 0.0 1.8 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 OAJ09982.1 - 1.5e-26 93.1 0.0 3.4e-16 59.8 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase DDE_1 PF03184.19 OAJ09983.1 - 8.3e-20 71.2 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC45 PF02724.14 OAJ09983.1 - 0.37 9.0 20.8 0.44 8.8 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BAF1_ABF1 PF04684.13 OAJ09983.1 - 0.56 9.2 21.0 0.82 8.7 21.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 OAJ09983.1 - 2.3 7.2 14.0 3.1 6.7 14.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Borrelia_P83 PF05262.11 OAJ09983.1 - 2.5 6.5 32.6 3.6 6.0 32.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SRP-alpha_N PF04086.13 OAJ09983.1 - 2.6 7.9 24.6 3.9 7.3 24.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NPAT_C PF15712.5 OAJ09983.1 - 3.5 6.2 16.5 4.3 5.9 16.5 1.1 1 0 0 1 1 1 0 NPAT C terminus Zip PF02535.22 OAJ09983.1 - 4.3 6.4 4.6 6.3 5.9 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 OAJ09983.1 - 7.5 3.5 10.8 8.9 3.3 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 OAJ09983.1 - 8.3 6.4 14.1 13 5.8 14.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4350 PF14258.6 OAJ09988.1 - 0.01 16.2 0.2 0.12 12.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Myc_N PF01056.18 OAJ09988.1 - 0.014 15.3 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 OAJ09988.1 - 2.1 7.6 3.5 3.3 6.9 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein FSAP_sig_propep PF03032.15 OAJ09988.1 - 2.4 8.3 4.2 4.3 7.4 4.2 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide CENP-B_dimeris PF09026.10 OAJ09988.1 - 3.9 7.9 9.2 10 6.6 9.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPTA PF01239.22 OAJ09989.1 - 5.9e-40 133.9 2.0 1.2e-09 37.6 0.3 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 OAJ09989.1 - 0.0027 18.0 0.6 3.3 8.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ09989.1 - 0.03 15.1 0.5 1 10.4 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RPEL PF02755.15 OAJ09990.1 - 2.3e-15 55.7 13.3 3e-06 26.7 1.6 3.9 4 0 0 4 4 4 3 RPEL repeat PilP PF04351.13 OAJ09990.1 - 0.39 10.7 5.4 1.6 8.7 2.0 2.4 1 1 2 3 3 3 0 Pilus assembly protein, PilP WW PF00397.26 OAJ09991.1 - 4.3e-07 29.9 3.2 8.2e-07 29.0 3.2 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 OAJ09991.1 - 5e-05 23.5 40.7 5e-05 23.5 40.7 3.6 1 1 2 3 3 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CYSTM PF12734.7 OAJ09991.1 - 0.051 13.9 1.0 0.051 13.9 1.0 7.5 4 1 0 4 4 3 0 Cysteine-rich TM module stress tolerance RR_TM4-6 PF06459.12 OAJ09991.1 - 0.06 13.2 8.7 0.079 12.8 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OAJ09991.1 - 0.87 8.7 6.1 1.2 8.3 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 OAJ09991.1 - 1.3 7.8 9.9 1.5 7.6 9.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 OAJ09991.1 - 1.9 8.5 2.8 2.8 8.0 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 OAJ09991.1 - 3.1 6.5 9.8 4.4 6.0 9.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4692 PF15763.5 OAJ09991.1 - 3.4 8.1 8.6 5.2 7.5 8.6 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) ATP-synt_E PF05680.12 OAJ09991.1 - 3.6 8.0 8.4 5.4 7.4 8.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain CSRNP_N PF16019.5 OAJ09991.1 - 4.3 7.2 13.6 6.4 6.6 13.6 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RT_RNaseH_2 PF17919.1 OAJ09994.1 - 1.1e-32 112.1 0.0 2.3e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09994.1 - 1.9e-27 95.6 0.0 4e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09994.1 - 4.6e-12 45.9 0.1 8.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos_2 PF12850.7 OAJ09994.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain rve PF00665.26 OAJ09995.1 - 3.5e-15 56.2 0.1 8.4e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ09995.1 - 0.021 14.6 0.0 0.085 12.6 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Vps5 PF09325.10 OAJ10002.1 - 4.1e-06 26.5 5.1 0.0056 16.3 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like IKBKB_SDD PF18397.1 OAJ10002.1 - 0.017 14.4 1.7 0.053 12.8 0.2 2.0 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain BAR_3_WASP_bdg PF10456.9 OAJ10002.1 - 0.068 12.6 0.6 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein PepSY_TM PF03929.16 OAJ10008.1 - 0.003 17.3 3.0 0.0034 17.1 3.0 1.2 1 0 0 1 1 1 1 PepSY-associated TM region bZIP_1 PF00170.21 OAJ10009.1 - 0.0038 17.3 8.3 0.0038 17.3 8.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ10009.1 - 0.0094 16.0 6.7 0.0094 16.0 6.7 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAJ10009.1 - 0.03 14.8 4.2 0.03 14.8 4.2 3.4 3 0 0 3 3 3 0 bZIP Maf transcription factor adh_short PF00106.25 OAJ10010.1 - 1.1e-20 74.0 0.0 3.3e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ10010.1 - 1.7e-16 60.5 0.1 2.5e-15 56.7 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ10010.1 - 5.3e-05 23.2 0.3 0.00012 22.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Pyr_redox_2 PF07992.14 OAJ10010.1 - 0.018 14.2 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ10010.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 OAJ10011.1 - 1.1e-35 121.1 14.1 9.8e-05 23.1 0.2 10.4 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ10011.1 - 3.2e-15 56.2 0.3 2.4e-05 24.5 0.0 5.9 3 3 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ10011.1 - 0.0012 17.6 0.0 0.012 14.3 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ10011.1 - 0.0012 17.7 0.1 0.44 9.2 0.0 3.3 3 1 0 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.6 OAJ10011.1 - 0.0074 15.7 0.1 1.4 8.2 0.0 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 OAJ10011.1 - 0.022 13.7 3.6 6.2 5.7 0.2 4.2 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OAJ10011.1 - 0.06 13.3 6.7 12 6.1 0.1 5.0 6 0 0 6 6 6 0 PQQ enzyme repeat WD40_like PF17005.5 OAJ10011.1 - 0.072 12.4 0.0 12 5.1 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain Utp8 PF10395.9 OAJ10011.1 - 0.14 10.6 0.0 2.2 6.7 0.0 2.0 2 0 0 2 2 2 0 Utp8 family PQQ_3 PF13570.6 OAJ10011.1 - 0.24 11.9 18.7 4.6 7.9 0.0 6.6 6 1 0 6 6 6 0 PQQ-like domain Peptidase_M43 PF05572.13 OAJ10016.1 - 1.3e-11 44.6 0.0 2.3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ10016.1 - 1.5e-05 25.5 0.0 2.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAJ10016.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ10016.1 - 0.0016 18.7 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 OAJ10016.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 OAJ10016.1 - 0.047 13.5 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.13 OAJ10017.1 - 8.4e-12 45.3 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ10017.1 - 7.3e-07 29.7 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ10017.1 - 0.00081 19.6 0.2 0.0015 18.7 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAJ10017.1 - 0.013 15.2 1.9 0.026 14.2 0.3 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ10017.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 OAJ10017.1 - 0.043 13.0 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 OAJ10017.1 - 0.2 11.6 0.1 0.71 9.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M54 Ytp1 PF10355.9 OAJ10018.1 - 8.3e-96 320.4 1.4 1.3e-95 319.8 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAJ10018.1 - 2e-14 53.2 0.5 2e-14 53.2 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) RAP1 PF07218.11 OAJ10023.1 - 2.4 6.3 8.3 3.6 5.8 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phage_integrase PF00589.22 OAJ10024.1 - 0.0044 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Gemin6 PF06372.12 OAJ10024.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Gemin6 protein PTPlike_phytase PF14566.6 OAJ10025.1 - 0.18 11.9 0.5 0.3 11.2 0.5 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate FAD_binding_3 PF01494.19 OAJ10029.1 - 1.3e-56 192.4 0.0 1.7e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NinB PF05772.12 OAJ10029.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 NinB protein Abhydrolase_1 PF00561.20 OAJ10030.1 - 6.3e-20 71.9 0.0 1.1e-19 71.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ10030.1 - 6.5e-17 62.9 0.2 9.8e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ10030.1 - 8.5e-13 48.1 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ10030.1 - 0.0072 16.0 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 OAJ10030.1 - 0.011 14.5 0.0 0.024 13.3 0.0 1.6 1 1 0 1 1 1 0 Ndr family Abhydrolase_5 PF12695.7 OAJ10030.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAJ10030.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 OAJ10030.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Amidohydro_1 PF01979.20 OAJ10031.1 - 1.3e-19 70.7 0.0 1.5e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAJ10031.1 - 1.1e-09 38.4 0.2 1.4e-09 38.0 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.16 OAJ10032.1 - 2.9e-12 46.2 29.5 2.9e-12 46.2 29.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Polysacc_deac_1 PF01522.21 OAJ10036.1 - 5.2e-23 81.3 0.0 1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OAJ10036.1 - 0.0075 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OAJ10036.1 - 0.13 11.9 0.2 0.27 10.8 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4263 PF14082.6 OAJ10036.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) DUF3493 PF11998.8 OAJ10037.1 - 0.029 14.5 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 PSK_trans_fac PF07704.11 OAJ10037.1 - 0.05 14.4 0.6 0.075 13.8 0.6 1.3 1 0 0 1 1 1 0 Rv0623-like transcription factor zf-CCHC PF00098.23 OAJ10038.1 - 0.001 19.0 4.5 0.0022 18.0 4.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ10038.1 - 0.071 13.1 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle TTRAP PF14203.6 OAJ10038.1 - 0.14 12.1 0.2 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Frag1 PF10277.9 OAJ10044.1 - 4.2e-18 65.7 5.7 4.7e-18 65.5 5.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cyt_bd_oxida_II PF02322.15 OAJ10044.1 - 0.011 15.1 2.4 0.014 14.8 2.4 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II PIG-U PF06728.13 OAJ10044.1 - 0.19 10.7 4.4 1.3 8.0 4.4 1.9 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U MRAP PF15183.6 OAJ10044.1 - 8.8 6.3 6.6 1.8 8.6 0.1 2.5 1 1 2 3 3 3 0 Melanocortin-2 receptor accessory protein family RWD PF05773.22 OAJ10045.1 - 3.5e-19 69.2 0.2 5.8e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 OAJ10045.1 - 7.1e-06 26.4 9.3 3.1e-05 24.4 9.3 2.1 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF3410 PF11890.8 OAJ10045.1 - 0.22 11.3 3.7 7.3 6.5 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3410) Peroxidase_2 PF01328.17 OAJ10047.1 - 5.9e-18 66.1 0.0 8.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Retrotran_gag_2 PF14223.6 OAJ10052.1 - 1.8e-10 40.6 0.1 2.2e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Kazal_2 PF07648.15 OAJ10053.1 - 0.068 13.3 1.7 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DDE_1 PF03184.19 OAJ10061.1 - 1.2e-18 67.4 0.0 2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ10061.1 - 1.4e-09 37.9 0.1 6.3e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TMEM191C PF15194.6 OAJ10061.1 - 0.031 14.5 0.5 0.083 13.1 0.5 1.7 1 0 0 1 1 1 0 TMEM191C family HTH_Tnp_ISL3 PF13542.6 OAJ10061.1 - 0.099 12.1 0.1 0.6 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF5338 PF17273.2 OAJ10061.1 - 8.8 6.5 7.1 0.43 10.7 0.4 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5338) MerR PF00376.23 OAJ10062.1 - 0.19 11.5 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein HisKA PF00512.25 OAJ10062.1 - 2.2 8.4 6.5 97 3.1 6.5 2.2 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain FAS_I_H PF18314.1 OAJ10068.1 - 8.4e-23 81.1 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAJ10068.1 - 2.9e-17 63.5 0.3 7e-17 62.2 0.1 1.7 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain Ammonium_transp PF00909.21 OAJ10070.1 - 1.4e-26 93.2 0.6 2.9e-15 55.9 0.0 2.1 1 1 1 2 2 2 2 Ammonium Transporter Family Malate_synthase PF01274.22 OAJ10070.1 - 4.5e-11 41.7 0.0 5.7e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Malate synthase YqzM PF14141.6 OAJ10070.1 - 0.012 15.7 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 YqzM-like protein RNA_pol_I_A49 PF06870.12 OAJ10071.1 - 3.2e-09 36.2 0.0 4.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Thymidylat_synt PF00303.19 OAJ10076.1 - 2e-100 335.4 0.0 2.9e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 OAJ10076.1 - 1.2e-36 126.2 0.7 1.8e-35 122.4 0.7 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Methyltransf_23 PF13489.6 OAJ10077.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ10077.1 - 0.15 12.8 0.2 1.2 9.9 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 OAJ10077.1 - 0.26 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Phage_holin_2_3 PF16080.5 OAJ10078.1 - 0.066 13.0 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 SPC25 PF06703.11 OAJ10084.1 - 1.3e-34 119.4 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Aminotran_5 PF00266.19 OAJ10085.1 - 4.7e-29 101.5 0.0 7.2e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 OAJ10085.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain GILT PF03227.16 OAJ10086.1 - 1.5e-14 54.1 0.1 2.5e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Pkinase PF00069.25 OAJ10094.1 - 1.1e-43 149.6 0.0 4.4e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10094.1 - 9.8e-20 70.9 0.0 8.2e-19 67.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ10094.1 - 0.00045 20.2 0.7 0.00065 19.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ10094.1 - 0.00047 19.6 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ10094.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ10094.1 - 0.034 12.9 0.1 0.09 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 OAJ10094.1 - 0.17 10.8 0.0 0.17 10.8 0.0 2.3 3 0 0 3 3 3 0 Haspin like kinase domain Glyco_hydro_3 PF00933.21 OAJ10098.1 - 3.5e-69 233.6 0.9 3.5e-69 233.6 0.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAJ10098.1 - 0.097 12.6 3.1 0.13 12.2 0.1 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain TLD PF07534.16 OAJ10099.1 - 7.8e-25 87.7 0.0 1.9e-21 76.7 0.0 3.1 2 1 0 2 2 2 2 TLD DUF4537 PF15057.6 OAJ10100.1 - 0.12 12.4 0.1 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Cyt-b5 PF00173.28 OAJ10106.1 - 1.7e-09 37.7 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ski2_N PF17911.1 OAJ10107.1 - 1.3e-41 141.6 0.0 2.1e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 OAJ10107.1 - 1.6e-08 34.5 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 OAJ10107.1 - 0.15 11.5 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein HECT PF00632.25 OAJ10108.1 - 4e-91 305.7 0.0 6.8e-91 304.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 OAJ10108.1 - 7.3 6.7 8.2 0.28 11.1 0.7 2.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif Retrotran_gag_2 PF14223.6 OAJ10113.1 - 4.1e-07 29.7 0.0 5.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ10113.1 - 1.1e-05 25.3 2.7 2.3e-05 24.2 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Fungus-induced PF10917.8 OAJ10113.1 - 1.8 8.9 5.1 3.8 7.9 5.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein Peptidase_M24 PF00557.24 OAJ10114.1 - 2.2e-38 132.0 0.0 3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 OAJ10114.1 - 0.023 14.8 5.0 0.039 14.1 5.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OAJ10114.1 - 0.54 8.5 5.7 0.73 8.1 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein LAT PF15234.6 OAJ10114.1 - 0.8 9.4 2.8 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells PGA2 PF07543.12 OAJ10114.1 - 5.7 6.9 13.1 0.26 11.3 6.0 2.2 3 0 0 3 3 3 0 Protein trafficking PGA2 NOA36 PF06524.12 OAJ10114.1 - 7.2 5.8 7.3 15 4.8 7.3 1.5 1 0 0 1 1 1 0 NOA36 protein RVT_2 PF07727.14 OAJ10116.1 - 5.4e-66 222.7 0.0 6.7e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OAJ10116.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ADIP PF11559.8 OAJ10132.1 - 0.095 12.8 27.3 1.4 9.0 11.2 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4574 PF15141.6 OAJ10132.1 - 0.26 11.2 5.5 0.91 9.5 5.0 2.2 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 KapB PF08810.10 OAJ10132.1 - 0.31 11.2 4.8 0.29 11.3 1.5 2.3 1 1 1 2 2 2 0 Kinase associated protein B Syntaxin-6_N PF09177.11 OAJ10132.1 - 0.32 11.6 19.4 0.085 13.4 5.9 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Nup88 PF10168.9 OAJ10132.1 - 1 7.1 20.5 1.3 6.7 20.5 1.1 1 0 0 1 1 1 0 Nuclear pore component UPF0242 PF06785.11 OAJ10132.1 - 1.8 8.6 31.1 0.087 12.9 20.0 2.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OAJ10132.1 - 2.3 8.6 32.6 0.77 10.2 14.4 2.5 1 1 1 2 2 2 0 Fez1 DUF4674 PF15719.5 OAJ10132.1 - 2.3 8.2 9.5 0.42 10.6 3.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4674) Transposase_21 PF02992.14 OAJ10133.1 - 2.5e-17 62.8 0.0 4.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ10133.1 - 0.0025 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Diphthami_syn_2 PF01902.17 OAJ10147.1 - 1.5e-38 132.5 0.0 4.9e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAJ10147.1 - 1.1e-21 77.1 0.1 9.7e-15 54.6 0.1 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.16 OAJ10147.1 - 0.0055 15.5 0.0 0.0081 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase VEFS-Box PF09733.9 OAJ10147.1 - 0.2 11.5 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 VEFS-Box of polycomb protein MRI PF15325.6 OAJ10147.1 - 3.4 8.8 6.6 28 5.9 0.1 3.3 3 0 0 3 3 3 0 Modulator of retrovirus infection NMD3 PF04981.13 OAJ10148.1 - 2.9e-80 269.3 0.5 3.7e-80 268.9 0.5 1.1 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAJ10148.1 - 0.033 14.2 8.4 0.33 11.0 5.3 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 OAJ10148.1 - 6.7 6.5 5.4 0.61 9.8 0.2 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain THUMP PF02926.17 OAJ10153.1 - 1.1e-13 51.6 0.1 2.8e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 THUMP domain Pkinase PF00069.25 OAJ10154.1 - 1.4e-64 218.0 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10154.1 - 1.6e-44 152.2 0.0 2.1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10154.1 - 1.7e-07 30.9 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ10154.1 - 8.9e-06 24.7 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ10154.1 - 6.1e-05 23.1 0.1 0.14 12.1 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAJ10154.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ10154.1 - 0.047 12.6 0.0 5.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain ParA PF10609.9 OAJ10160.1 - 2.2e-65 220.5 0.1 4.6e-33 114.7 0.0 3.1 3 0 0 3 3 3 3 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ10160.1 - 5.9e-10 39.3 0.5 6.4e-08 32.7 0.5 2.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAJ10160.1 - 2.4e-06 27.6 0.1 8.7e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 OAJ10160.1 - 0.0027 17.6 0.3 0.27 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 OAJ10160.1 - 0.0031 16.8 0.0 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 OAJ10160.1 - 0.0034 17.0 0.0 0.0094 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OAJ10160.1 - 0.046 12.9 0.6 0.26 10.4 0.1 2.2 2 1 1 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.18 OAJ10160.1 - 0.082 12.3 0.0 0.17 11.3 0.1 1.4 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SDA1 PF05285.12 OAJ10166.1 - 9.4e-79 265.3 46.0 9.4e-79 265.3 46.0 3.4 3 1 0 3 3 3 1 SDA1 NUC130_3NT PF08158.12 OAJ10166.1 - 5.3e-15 55.5 0.4 1e-14 54.5 0.4 1.5 1 0 0 1 1 1 1 NUC130/3NT domain DEAD PF00270.29 OAJ10167.1 - 3.8e-33 114.7 0.0 1.6e-32 112.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ10167.1 - 3.6e-18 65.9 0.0 1.3e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10167.1 - 4.6e-07 30.0 0.0 9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ10167.1 - 0.018 15.3 2.3 0.56 10.5 0.7 3.3 2 1 0 2 2 2 0 AAA domain Hairy_orange PF07527.13 OAJ10167.1 - 0.33 11.2 1.0 11 6.3 0.0 3.1 4 0 0 4 4 4 0 Hairy Orange UQ_con PF00179.26 OAJ10168.1 - 2.2e-41 140.8 0.0 2.9e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAJ10168.1 - 0.011 16.1 0.5 0.017 15.4 0.5 1.4 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 OAJ10168.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 OAJ10168.1 - 0.077 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Fip1 PF05182.13 OAJ10168.1 - 0.19 11.3 0.2 0.38 10.3 0.2 1.5 1 0 0 1 1 1 0 Fip1 motif Sacchrp_dh_NADP PF03435.18 OAJ10174.1 - 3.8e-07 30.4 0.4 2.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain SR-25 PF10500.9 OAJ10181.1 - 0.039 13.6 14.1 0.067 12.8 14.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 OAJ10181.1 - 1.4 8.6 7.9 2.9 7.5 7.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 OAJ10181.1 - 3.9 5.7 12.0 8.3 4.6 12.0 1.5 1 0 0 1 1 1 0 CDC45-like protein V-ATPase_C PF03223.15 OAJ10187.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit C RVT_2 PF07727.14 OAJ10189.1 - 5.3e-49 167.0 0.0 6.2e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_22 PF08092.11 OAJ10189.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Magi peptide toxin family rve PF00665.26 OAJ10190.1 - 9.2e-13 48.4 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10190.1 - 5.1e-07 29.5 0.5 1.8e-06 27.7 0.3 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain LtrA PF06772.11 OAJ10195.1 - 1.5e-31 109.9 31.5 3e-16 59.6 22.1 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) CDV3 PF15359.6 OAJ10195.1 - 0.48 10.9 7.4 3.2 8.3 7.1 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 ABC_membrane PF00664.23 OAJ10201.1 - 9.7e-113 376.4 23.2 6.9e-60 203.0 11.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ10201.1 - 1.9e-68 229.2 0.0 3.3e-33 115.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ10201.1 - 4.2e-17 62.3 1.1 9e-05 22.0 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAJ10201.1 - 3.4e-11 42.6 0.7 0.0015 17.4 0.1 4.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAJ10201.1 - 6.5e-08 32.2 0.7 0.0032 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ10201.1 - 1.3e-07 31.9 0.2 0.053 13.8 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAJ10201.1 - 1.3e-06 28.3 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAJ10201.1 - 1.5e-06 28.2 0.2 0.13 12.0 0.0 3.6 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ10201.1 - 2e-06 28.3 0.7 0.026 14.9 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAJ10201.1 - 9.1e-06 26.3 0.4 0.3 11.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OAJ10201.1 - 1e-05 25.5 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 OAJ10201.1 - 2.6e-05 23.9 0.3 0.045 13.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OAJ10201.1 - 5.4e-05 22.6 0.0 0.087 12.1 0.0 3.0 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 OAJ10201.1 - 0.00011 21.9 0.8 0.51 10.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 OAJ10201.1 - 0.00015 22.2 0.2 0.77 10.2 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OAJ10201.1 - 0.00025 21.2 3.0 1.3 9.3 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAJ10201.1 - 0.0009 19.3 0.1 3.8 7.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 OAJ10201.1 - 0.0011 19.2 0.2 2.4 8.2 0.0 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain G-alpha PF00503.20 OAJ10201.1 - 0.0015 17.8 0.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 OAJ10201.1 - 0.0032 18.0 0.0 6.8 7.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 OAJ10201.1 - 0.0049 16.6 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 OAJ10201.1 - 0.0052 16.7 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 OAJ10201.1 - 0.0088 16.1 0.0 5.8 7.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 OAJ10201.1 - 0.011 15.9 0.0 2.8 8.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ10201.1 - 0.018 14.3 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 OAJ10201.1 - 0.022 14.3 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ10201.1 - 0.029 14.7 0.0 7.4 7.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase APS_kinase PF01583.20 OAJ10201.1 - 0.032 14.1 0.1 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 OAJ10201.1 - 0.034 14.4 1.0 8.7 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 OAJ10201.1 - 0.043 13.6 0.0 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 OAJ10201.1 - 0.052 12.7 0.0 9.3 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAJ10201.1 - 0.1 12.3 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 OAJ10201.1 - 0.11 12.1 0.1 11 5.6 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 OAJ10201.1 - 0.12 12.8 0.3 31 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAJ10201.1 - 0.16 12.0 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAJ10201.1 - 0.2 11.0 0.8 8.2 5.7 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NatB_MDM20 PF09797.9 OAJ10212.1 - 3.5e-57 194.1 0.1 8.3e-57 192.8 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Med11 PF10280.9 OAJ10212.1 - 0.034 14.6 0.3 0.58 10.6 0.0 2.9 3 0 0 3 3 3 0 Mediator complex protein DnaJ PF00226.31 OAJ10213.1 - 1.1e-24 86.4 0.5 1.3e-24 86.1 0.5 1.1 1 0 0 1 1 1 1 DnaJ domain RRM_3 PF08777.11 OAJ10213.1 - 0.054 13.5 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif COesterase PF00135.28 OAJ10214.1 - 3.3e-94 316.6 0.1 5.4e-94 315.9 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family DnaJ_C PF01556.18 OAJ10214.1 - 2.7e-32 111.9 0.0 4.4e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OAJ10214.1 - 1e-12 48.2 18.7 1.8e-12 47.4 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Abhydrolase_3 PF07859.13 OAJ10214.1 - 3.3e-06 27.1 1.3 0.0015 18.4 0.1 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Anti-TRAP PF15777.5 OAJ10214.1 - 2.1 8.4 14.8 0.6 10.1 4.1 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cpn60_TCP1 PF00118.24 OAJ10223.1 - 3e-85 286.7 7.6 5.4e-85 285.9 7.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.22 OAJ10224.1 - 1.3e-09 37.7 0.0 4.6e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ10224.1 - 0.0043 16.6 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OAJ10224.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Cpn10 PF00166.21 OAJ10225.1 - 1.5e-26 92.2 0.0 1.7e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PIF1 PF05970.14 OAJ10230.1 - 1.5e-54 185.6 0.0 2e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ10230.1 - 7.7e-31 107.8 0.0 1.4e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ10230.1 - 1.1e-09 38.3 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ10230.1 - 5.7e-05 23.5 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ10230.1 - 0.0013 19.1 0.1 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAJ10230.1 - 0.0071 16.3 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF2791 PF10923.8 OAJ10230.1 - 0.0079 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Collagen PF01391.18 OAJ10240.1 - 5.9e-13 48.4 81.7 0.00021 21.0 17.5 3.8 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Phage_integrase PF00589.22 OAJ10247.1 - 0.12 12.1 2.3 11 5.7 0.1 2.8 3 0 0 3 3 3 0 Phage integrase family Dynactin_p62 PF05502.13 OAJ10247.1 - 0.23 10.2 5.9 0.36 9.5 5.9 1.2 1 0 0 1 1 1 0 Dynactin p62 family V-ATPase_G PF03179.15 OAJ10248.1 - 0.013 16.0 0.4 0.013 16.0 0.4 2.2 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Helicase_C PF00271.31 OAJ10258.1 - 5.6e-14 52.4 0.0 4.3e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ10258.1 - 3.5e-10 39.9 0.0 2e-09 37.5 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ10258.1 - 9.7e-06 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RT_RNaseH PF17917.1 OAJ10259.1 - 7.4e-10 39.0 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10259.1 - 2.3e-05 24.6 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ10259.1 - 0.00018 21.5 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DNA_mis_repair PF01119.19 OAJ10264.1 - 4.6e-18 65.0 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TPR_12 PF13424.6 OAJ10264.1 - 2.6e-09 37.2 3.5 4.6e-05 23.6 0.4 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ10264.1 - 0.0013 18.8 0.6 0.56 10.3 0.1 2.5 1 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OAJ10264.1 - 0.0023 17.7 0.6 0.81 9.6 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ10264.1 - 0.17 12.0 0.2 12 6.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ10264.1 - 0.2 11.8 0.2 18 5.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ10265.1 - 0.00011 22.1 1.3 0.00015 21.7 1.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 ICL PF00463.21 OAJ10265.1 - 0.026 13.0 0.0 0.03 12.8 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Dimer_Tnp_hAT PF05699.14 OAJ10266.1 - 2.5e-11 43.2 0.0 4.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CPSase_L_D3 PF02787.19 OAJ10266.1 - 0.14 12.6 0.1 0.48 10.8 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain C2 PF00168.30 OAJ10272.1 - 3.2e-72 239.4 0.2 1.4e-21 76.7 0.0 4.5 4 0 0 4 4 4 4 C2 domain MMM1 PF10296.9 OAJ10272.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Autophagy_N PF03986.13 OAJ10273.1 - 4e-42 143.4 0.0 7.7e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OAJ10273.1 - 1.5e-18 67.1 0.1 2.9e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OAJ10273.1 - 4.1e-11 42.2 0.4 7.1e-11 41.4 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal rve PF00665.26 OAJ10278.1 - 8e-05 22.8 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 OAJ10278.1 - 0.0001 22.0 0.1 0.00071 19.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain COG2 PF06148.11 OAJ10278.1 - 0.0014 18.7 0.2 0.0039 17.3 0.2 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 HTH_Crp_2 PF13545.6 OAJ10278.1 - 0.041 13.9 0.0 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 OAJ10278.1 - 0.043 13.8 0.3 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 HTH domain Sigma70_r4_2 PF08281.12 OAJ10278.1 - 0.34 10.6 1.8 0.75 9.5 0.0 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 PHD PF00628.29 OAJ10279.1 - 3.6e-06 26.8 9.4 6.6e-06 25.9 9.4 1.5 1 0 0 1 1 1 1 PHD-finger ubiquitin PF00240.23 OAJ10284.1 - 2.8e-16 59.0 0.0 2.2e-05 24.1 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family ubiquitin PF00240.23 OAJ10285.1 - 7.3e-19 67.3 0.0 8.5e-10 38.2 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OAJ10285.1 - 2.9e-09 36.6 0.2 5.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ10286.1 - 1.9e-09 37.1 0.1 0.00039 20.1 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OAJ10286.1 - 0.0056 16.5 0.1 0.061 13.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GP40 PF11025.8 OAJ10286.1 - 0.0082 15.9 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotein GP40 of Cryptosporidium DUF3244 PF11589.8 OAJ10286.1 - 0.055 13.5 0.6 3 8.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) RBD PF02196.15 OAJ10286.1 - 0.13 12.4 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain MFS_1 PF07690.16 OAJ10293.1 - 3.2e-27 95.4 32.9 4.4e-27 94.9 32.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Endostatin PF06482.11 OAJ10294.1 - 0.069 12.6 7.6 0.08 12.4 7.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Spt20 PF12090.8 OAJ10294.1 - 0.082 12.5 10.9 0.09 12.4 10.9 1.1 1 0 0 1 1 1 0 Spt20 family Sec10 PF07393.11 OAJ10294.1 - 0.14 10.5 5.9 0.16 10.4 5.9 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 TFIIA PF03153.13 OAJ10294.1 - 0.61 10.0 12.1 0.68 9.9 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 OAJ10294.1 - 0.76 10.0 6.8 0.96 9.7 6.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ndc1_Nup PF09531.10 OAJ10294.1 - 1.2 7.8 9.5 1.3 7.6 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_REP PF05086.12 OAJ10294.1 - 1.2 7.0 7.3 1.3 6.9 7.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein VIR_N PF15912.5 OAJ10294.1 - 1.3 8.6 8.4 1.6 8.2 8.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Presenilin PF01080.17 OAJ10294.1 - 1.9 7.2 8.4 2.1 7.0 8.4 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAJ10294.1 - 2.3 8.0 6.7 2.8 7.7 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OAJ10294.1 - 3.2 6.9 5.2 3.5 6.8 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mucin PF01456.17 OAJ10294.1 - 5.7 6.9 15.7 8.6 6.3 15.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Reo_P9 PF06043.11 OAJ10294.1 - 9.1 5.6 6.4 12 5.1 6.4 1.1 1 0 0 1 1 1 0 Reovirus P9-like family BPL_N PF09825.9 OAJ10297.1 - 3.4e-95 319.3 0.0 4.2e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAJ10297.1 - 2.6e-17 63.0 0.0 4.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 OAJ10297.1 - 0.15 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NAD_binding_4 PF07993.12 OAJ10298.1 - 7.8e-21 74.4 0.0 2.5e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 OAJ10298.1 - 3.9e-14 52.7 0.0 1e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ10298.1 - 0.0022 17.9 0.0 0.023 14.6 0.0 2.4 1 1 0 1 1 1 1 KR domain FrhB_FdhB_N PF04422.13 OAJ10298.1 - 0.0033 17.5 0.0 0.36 11.0 0.0 3.3 3 0 0 3 3 3 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Polysacc_synt_2 PF02719.15 OAJ10298.1 - 0.021 14.0 0.1 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RVT_2 PF07727.14 OAJ10302.1 - 7.2e-62 209.2 0.0 1.1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAJ10302.1 - 2.8e-18 65.9 0.1 4.6e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ10302.1 - 7.2e-15 55.2 0.2 2.1e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10302.1 - 1.1e-08 34.8 0.9 1e-07 31.7 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ10302.1 - 0.0019 17.9 0.0 0.0073 16.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RNA_bind PF08675.11 OAJ10302.1 - 0.043 13.8 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 RNA binding domain Propeptide_C1 PF08127.13 OAJ10302.1 - 0.093 12.6 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Peptidase family C1 propeptide zf-CCHC PF00098.23 OAJ10302.1 - 0.14 12.3 10.0 0.1 12.7 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.28 OAJ10307.1 - 1.6e-36 126.8 0.1 3.1e-36 125.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ10307.1 - 9.5e-17 61.2 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TFIIA PF03153.13 OAJ10307.1 - 1.6 8.7 21.8 2.5 8.0 21.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 OAJ10309.1 - 7.8e-43 145.5 0.0 8.8e-43 145.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ10309.1 - 0.008 15.9 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B HTH_57 PF18679.1 OAJ10309.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 ThcOx helix turn helix domain DUF3128 PF11326.8 OAJ10310.1 - 0.0021 18.4 0.8 0.0031 17.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 OAJ10310.1 - 0.0061 16.8 1.8 0.064 13.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 OAJ10310.1 - 0.016 15.2 2.0 0.023 14.7 2.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 OAJ10310.1 - 0.024 14.9 1.3 0.038 14.2 1.3 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.9 OAJ10310.1 - 0.03 14.6 0.8 0.048 14.0 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 OAJ10310.1 - 1 9.6 7.8 5 7.4 8.1 1.9 1 1 2 3 3 3 0 CHCH domain TFIID_NTD2 PF04494.15 OAJ10311.1 - 1.8e-29 102.6 0.0 4.6e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 OAJ10311.1 - 2.4e-17 62.9 1.5 2.3e-06 28.2 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.11 OAJ10311.1 - 0.007 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 LisH E_Pc_C PF06752.12 OAJ10319.1 - 0.019 15.1 1.0 0.019 15.1 1.0 4.1 3 1 0 4 4 4 0 Enhancer of Polycomb C-terminus FAD_binding_3 PF01494.19 OAJ10320.1 - 0.0062 15.8 0.0 0.0082 15.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DNA_pol_phi PF04931.13 OAJ10322.1 - 0.013 13.7 0.4 0.017 13.3 0.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi HSP70 PF00012.20 OAJ10326.1 - 1.1e-43 149.3 0.0 1.5e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Methyltransf_8 PF05148.15 OAJ10326.1 - 0.00053 19.9 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MmgE_PrpD PF03972.14 OAJ10327.1 - 6.6e-91 305.0 0.5 7.9e-91 304.8 0.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MmgE_PrpD PF03972.14 OAJ10328.1 - 1.2e-10 40.5 0.1 1.9e-10 39.9 0.1 1.3 1 1 0 1 1 1 1 MmgE/PrpD family ADH_zinc_N_2 PF13602.6 OAJ10335.1 - 3.8e-15 57.1 0.0 9.2e-14 52.6 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ10335.1 - 1.2e-14 54.4 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.22 OAJ10335.1 - 0.004 17.1 0.1 0.0069 16.3 0.1 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain ADH_N PF08240.12 OAJ10335.1 - 0.0097 15.8 0.0 0.064 13.1 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ10335.1 - 0.13 12.2 0.1 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase NAD_binding_4 PF07993.12 OAJ10336.1 - 1.5e-24 86.5 0.0 4.1e-24 85.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 OAJ10336.1 - 5.8e-20 71.3 0.0 2.2e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 OAJ10336.1 - 3.4e-15 56.2 0.0 7.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ10336.1 - 2.8e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ10336.1 - 5.6e-06 25.6 0.1 0.0015 17.6 0.0 2.7 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ10336.1 - 0.0067 16.4 0.1 0.048 13.6 0.1 2.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ10336.1 - 0.0087 15.2 0.0 0.59 9.2 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAJ10336.1 - 0.0093 15.9 0.4 0.46 10.4 0.0 3.5 2 1 1 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 OAJ10336.1 - 0.066 12.8 0.1 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family AMP-binding_C PF13193.6 OAJ10336.1 - 0.091 13.8 0.2 0.42 11.6 0.1 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Dmrt1 PF12374.8 OAJ10344.1 - 0.013 16.0 4.6 0.042 14.3 4.6 1.7 1 1 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Histone PF00125.24 OAJ10345.1 - 2.9e-46 157.1 0.3 3.3e-46 156.9 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ10345.1 - 0.00017 21.9 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ10345.1 - 0.00025 21.1 0.1 0.00039 20.5 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ10345.1 - 0.014 15.6 0.1 0.022 15.0 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OAJ10345.1 - 0.12 13.0 0.7 0.15 12.7 0.7 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain preATP-grasp_3 PF18301.1 OAJ10347.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain Hamartin PF04388.12 OAJ10347.1 - 2.1 6.9 11.2 3 6.4 11.2 1.2 1 0 0 1 1 1 0 Hamartin protein FAM199X PF15814.5 OAJ10347.1 - 5.1 6.1 10.3 7.7 5.5 10.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Period_C PF12114.8 OAJ10347.1 - 6.1 6.4 9.9 11 5.6 9.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region zf-BED PF02892.15 OAJ10348.1 - 0.002 18.1 1.8 0.0049 16.9 1.8 1.6 1 0 0 1 1 1 1 BED zinc finger DHQ_synthase PF01761.20 OAJ10354.1 - 1.4e-46 158.8 0.0 1.9e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAJ10354.1 - 3.2e-09 36.9 0.0 4.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1912 PF08930.10 OAJ10356.1 - 0.015 15.4 0.3 0.087 13.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) Cas_CT1975 PF09344.10 OAJ10363.1 - 6e-54 183.9 3.0 7e-54 183.7 3.0 1.0 1 0 0 1 1 1 1 CT1975-like protein TP_methylase PF00590.20 OAJ10363.1 - 0.022 14.7 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Cas_Cas5d PF09704.10 OAJ10364.1 - 3.2e-36 125.2 0.1 4e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) CRISPR_Cse1 PF09481.10 OAJ10365.1 - 1.3e-90 304.7 0.4 1.5e-90 304.5 0.4 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) CRISPR_Cse2 PF09485.10 OAJ10366.1 - 8.3e-18 65.3 3.1 9.8e-18 65.0 3.1 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) KilA-N PF04383.13 OAJ10367.1 - 2.9e-09 36.7 0.0 3.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 KilA-N domain HD_6 PF18019.1 OAJ10369.1 - 3.4e-44 151.3 1.9 8.4e-44 150.1 1.9 1.7 1 0 0 1 1 1 1 HD domain DEAD PF00270.29 OAJ10369.1 - 5e-05 23.1 0.2 0.00062 19.6 0.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ10369.1 - 0.00027 21.0 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ10369.1 - 0.0041 17.4 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HAD PF12710.7 OAJ10369.1 - 0.084 13.3 1.0 0.49 10.8 0.1 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Septin PF00735.18 OAJ10376.1 - 2.2e-110 368.4 0.2 2.7e-110 368.1 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ10376.1 - 3.9e-09 36.6 0.0 1.5e-08 34.7 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ10376.1 - 4.1e-05 23.5 0.1 0.00034 20.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ10376.1 - 0.00023 20.8 0.7 0.011 15.3 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 OAJ10376.1 - 0.00023 20.6 1.0 0.00044 19.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 OAJ10376.1 - 0.0007 19.7 0.2 0.94 9.5 0.1 2.6 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 OAJ10376.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 OAJ10376.1 - 0.02 14.4 0.0 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Microtub_bd PF16796.5 OAJ10376.1 - 0.024 14.6 0.2 0.39 10.7 0.0 2.6 2 1 2 4 4 4 0 Microtubule binding ABC_tran PF00005.27 OAJ10376.1 - 0.033 14.7 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OAJ10376.1 - 0.04 14.2 0.1 0.095 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ10376.1 - 0.2 12.0 1.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Ion_trans PF00520.31 OAJ10378.1 - 7.2e-10 38.5 8.5 8.2e-09 35.0 8.5 2.1 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OAJ10378.1 - 1.1e-05 24.3 10.8 0.001 17.9 4.9 2.5 3 0 0 3 3 3 2 Polycystin cation channel Yip1 PF04893.17 OAJ10378.1 - 0.05 13.3 7.0 0.79 9.4 5.1 2.4 2 0 0 2 2 2 0 Yip1 domain PACT_coil_coil PF10495.9 OAJ10385.1 - 2.8e-14 53.4 0.1 2.8e-14 53.4 0.1 3.5 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 OAJ10385.1 - 0.26 11.3 87.3 0.49 10.4 2.1 6.1 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 OAJ10385.1 - 6.5 6.2 86.1 1.4 8.4 3.0 5.0 2 1 2 4 4 4 0 Intermediate filament protein GAS PF13851.6 OAJ10385.1 - 9.2 5.6 77.9 0.017 14.5 10.3 5.4 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Collagen PF01391.18 OAJ10386.1 - 4.2e-20 71.3 72.0 2.9e-08 33.3 23.0 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) 2OG-FeII_Oxy_3 PF13640.6 OAJ10387.1 - 3.9e-06 27.6 0.0 8.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exc PF07825.11 OAJ10387.1 - 0.12 12.4 0.1 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Excisionase-like protein Kelch_4 PF13418.6 OAJ10392.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ10392.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Kelch motif CHDCT2 PF08074.11 OAJ10393.1 - 0.053 13.7 1.1 0.072 13.3 1.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Spc7 PF08317.11 OAJ10393.1 - 0.086 11.7 3.1 0.11 11.4 3.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.21 OAJ10393.1 - 0.094 12.3 4.5 0.12 11.9 4.5 1.0 1 0 0 1 1 1 0 Intermediate filament protein FapA PF03961.13 OAJ10393.1 - 0.13 10.8 0.1 0.15 10.6 0.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 OAJ10393.1 - 0.18 11.9 6.2 0.082 13.0 3.3 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding RT_RNaseH_2 PF17919.1 OAJ10399.1 - 4e-14 52.4 0.0 1e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10399.1 - 1.9e-13 50.6 0.0 4.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10399.1 - 7.3e-09 35.5 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KDZ PF18758.1 OAJ10399.1 - 2.4e-06 27.3 0.5 3.9e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Asp_protease_2 PF13650.6 OAJ10400.1 - 8.9e-07 29.5 0.1 2.1e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10400.1 - 1.9e-06 28.3 0.0 4.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.8 OAJ10400.1 - 0.0003 20.5 0.7 9.3 6.2 0.0 4.2 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like Asp_protease PF09668.10 OAJ10400.1 - 0.0021 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 OAJ10400.1 - 0.051 13.1 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase RVP PF00077.20 OAJ10400.1 - 0.052 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ10400.1 - 2.3 8.5 6.5 4.6 7.5 6.5 1.5 1 0 0 1 1 1 0 Zinc knuckle VHP PF02209.19 OAJ10407.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain PAT1 PF09770.9 OAJ10413.1 - 1.3e-14 53.5 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SdpI PF13630.6 OAJ10413.1 - 0.043 13.9 0.6 0.095 12.8 0.6 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family SRRM_C PF15230.6 OAJ10413.1 - 3.9 8.1 6.3 0.99 10.0 1.3 2.3 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus PAT1 PF09770.9 OAJ10414.1 - 0.0018 16.7 2.7 0.14 10.4 0.0 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Mg_trans_NIPA PF05653.14 OAJ10415.1 - 1.1e-25 90.4 8.5 8.9e-15 54.6 2.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Neurensin PF14927.6 OAJ10415.1 - 0.15 11.8 2.2 10 5.8 0.2 2.7 2 0 0 2 2 2 0 Neurensin Tetraspanin PF00335.20 OAJ10415.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.6 3 0 0 3 3 3 0 Tetraspanin family TMEM234 PF10639.9 OAJ10415.1 - 0.78 9.8 6.1 0.17 11.9 0.7 2.4 3 0 0 3 3 3 0 Putative transmembrane family 234 TFIIA PF03153.13 OAJ10416.1 - 1.6 8.7 10.9 1.2 9.1 9.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 OAJ10416.1 - 2.5 7.7 4.3 4.6 6.8 4.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA PF00004.29 OAJ10418.1 - 1.9e-26 93.1 0.0 2.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ10418.1 - 3.7e-06 27.4 0.2 0.002 18.6 0.1 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ10418.1 - 1.1e-05 25.7 0.1 0.11 12.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ10418.1 - 0.001 19.1 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAJ10418.1 - 0.0017 18.1 1.0 0.027 14.2 1.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ10418.1 - 0.0025 18.0 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAJ10418.1 - 0.0081 15.8 1.1 0.059 12.9 1.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ10418.1 - 0.02 15.4 0.0 0.037 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAJ10418.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.5 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAJ10418.1 - 0.028 13.6 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 OAJ10418.1 - 0.045 14.0 0.0 0.082 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Beta_protein PF14350.6 OAJ10418.1 - 0.053 12.9 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Beta protein AAA_14 PF13173.6 OAJ10418.1 - 0.053 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAJ10418.1 - 0.12 12.7 0.9 0.55 10.6 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 OAJ10418.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain IPT PF01745.16 OAJ10418.1 - 0.15 11.5 0.1 0.41 10.0 0.1 1.6 2 0 0 2 2 2 0 Isopentenyl transferase RXT2_N PF08595.11 OAJ10419.1 - 0.05 13.6 4.5 0.082 12.9 4.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 OAJ10419.1 - 0.15 10.9 8.6 0.23 10.3 8.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.11 OAJ10419.1 - 0.55 8.7 4.3 0.62 8.5 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SGT1 PF07093.11 OAJ10419.1 - 0.56 8.6 7.1 0.71 8.2 7.1 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.9 OAJ10419.1 - 0.59 9.2 14.4 0.94 8.5 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 OAJ10419.1 - 0.72 9.1 11.5 0.95 8.7 11.5 1.1 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 OAJ10419.1 - 0.74 9.4 7.6 1.4 8.5 7.6 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PPP4R2 PF09184.11 OAJ10419.1 - 2.8 7.4 15.0 4.3 6.8 15.0 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4820 PF16091.5 OAJ10419.1 - 5.4 6.3 6.7 8.4 5.7 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4637 PF15470.6 OAJ10419.1 - 6.9 6.4 9.1 12 5.6 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FAM176 PF14851.6 OAJ10419.1 - 7.4 6.2 8.9 15 5.2 8.9 1.5 1 0 0 1 1 1 0 FAM176 family Helitron_like_N PF14214.6 OAJ10425.1 - 1.1e-33 117.0 0.4 1.1e-33 117.0 0.4 2.5 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus DUF747 PF05346.11 OAJ10426.1 - 2.5e-112 375.5 0.2 7.6e-99 331.2 0.5 2.2 2 0 0 2 2 2 2 Eukaryotic membrane protein family Kinesin PF00225.23 OAJ10428.1 - 2.4e-71 240.4 0.4 3.3e-43 147.9 0.0 2.9 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 OAJ10428.1 - 6e-10 39.2 0.0 8.5e-06 25.8 0.0 3.7 4 0 0 4 4 4 2 Microtubule binding CENP-B_dimeris PF09026.10 OAJ10429.1 - 0.033 14.6 34.1 1.7 9.1 7.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain TFB6 PF17110.5 OAJ10429.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.3 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Pkinase PF00069.25 OAJ10432.1 - 4.2e-66 223.0 0.0 6.7e-66 222.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10432.1 - 1.3e-37 129.5 0.0 6.6e-35 120.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ10432.1 - 0.0011 17.9 0.0 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAJ10432.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OAJ10432.1 - 0.11 12.1 0.1 0.38 10.3 0.0 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 OAJ10432.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ10432.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.27 OAJ10433.1 - 1e-70 233.7 5.3 4.1e-23 81.1 0.1 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ10433.1 - 0.016 14.4 0.3 0.18 10.9 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease GAD-like PF08887.11 OAJ10433.1 - 0.031 14.1 0.2 4.1 7.2 0.1 2.4 2 0 0 2 2 2 0 GAD-like domain ERG4_ERG24 PF01222.17 OAJ10434.1 - 1.1e-119 400.0 22.0 1.3e-119 399.8 22.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family RVT_1 PF00078.27 OAJ10439.1 - 1.2e-23 83.9 0.0 2.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10439.1 - 6.2e-20 71.1 0.2 7.2e-13 48.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10439.1 - 3.4e-14 52.7 0.0 8.4e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ10439.1 - 3.5e-13 49.8 0.0 1.1e-08 35.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10439.1 - 7.6e-11 42.3 0.1 7e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ10439.1 - 0.00093 19.4 0.0 0.027 14.7 0.0 2.7 2 0 0 2 2 2 1 H2C2 zinc finger Asp_protease_2 PF13650.6 OAJ10439.1 - 0.0012 19.4 0.4 0.0044 17.6 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10439.1 - 0.051 14.2 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ10439.1 - 0.16 12.3 0.0 0.67 10.3 0.0 2.1 2 1 0 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OAJ10440.1 - 0.092 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 OAJ10447.1 - 3.4e-23 82.3 0.0 5.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10447.1 - 1.5e-20 73.0 0.0 3.1e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10447.1 - 2.1e-16 60.1 0.0 2.1e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10447.1 - 3.9e-16 58.9 0.1 9.6e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 OAJ10447.1 - 6.2e-05 23.6 0.0 0.0002 21.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10447.1 - 0.0053 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ10447.1 - 0.039 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger DUF1542 PF07564.11 OAJ10451.1 - 0.043 13.9 0.3 0.078 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) CbiC PF02570.15 OAJ10451.1 - 0.14 11.8 0.3 0.29 10.7 0.2 1.5 1 1 1 2 2 2 0 Precorrin-8X methylmutase Transferase PF02458.15 OAJ10453.1 - 1e-05 24.4 0.0 0.00059 18.6 0.0 2.8 2 1 0 2 2 2 2 Transferase family DEAD PF00270.29 OAJ10454.1 - 1.9e-48 164.5 0.0 3.5e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ10454.1 - 1.4e-31 109.1 0.0 4.8e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10454.1 - 0.00012 22.2 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HeH PF12949.7 OAJ10462.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain DUF3136 PF11334.8 OAJ10463.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) SPATA48 PF15073.6 OAJ10463.1 - 0.13 12.6 0.3 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 CBP_CCPA PF17040.5 OAJ10471.1 - 0.12 13.0 3.2 1.6 9.3 0.3 2.2 2 0 0 2 2 2 0 Cellulose-complementing protein A Pox_Ag35 PF03286.14 OAJ10472.1 - 0.001 18.9 16.4 0.0015 18.3 16.4 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Nop14 PF04147.12 OAJ10472.1 - 0.0047 15.2 27.3 0.006 14.9 27.3 1.1 1 0 0 1 1 1 1 Nop14-like family IFT57 PF10498.9 OAJ10472.1 - 0.0086 15.1 11.7 0.015 14.2 11.7 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4820 PF16091.5 OAJ10472.1 - 0.014 14.8 7.3 0.024 14.0 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Myb_DNA-bind_3 PF12776.7 OAJ10472.1 - 0.026 15.5 0.1 0.045 14.7 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CNDH2_C PF16858.5 OAJ10472.1 - 0.028 14.3 11.1 0.042 13.7 11.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RR_TM4-6 PF06459.12 OAJ10472.1 - 0.041 13.7 12.7 0.062 13.1 12.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 OAJ10472.1 - 0.083 11.9 6.3 0.13 11.2 6.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 OAJ10472.1 - 0.14 11.3 18.3 0.18 10.9 18.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SAPS PF04499.15 OAJ10472.1 - 0.21 10.3 8.1 0.23 10.2 8.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RPN2_C PF18004.1 OAJ10472.1 - 0.22 11.4 17.8 0.46 10.4 17.8 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFIIA PF03153.13 OAJ10472.1 - 0.24 11.4 16.4 0.27 11.2 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 OAJ10472.1 - 0.29 10.0 1.7 0.34 9.8 1.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RNA_pol_Rpc4 PF05132.14 OAJ10472.1 - 0.3 11.5 10.2 2.1 8.8 10.3 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 FGF-BP1 PF06473.12 OAJ10472.1 - 0.37 10.6 5.7 0.62 9.9 5.7 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NARP1 PF12569.8 OAJ10472.1 - 0.38 9.6 10.9 0.6 9.0 10.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_3_Rpc31 PF11705.8 OAJ10472.1 - 0.49 10.6 36.1 1.4 9.1 36.1 1.8 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NPR3 PF03666.13 OAJ10472.1 - 0.63 8.8 10.7 0.91 8.2 10.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 OAJ10472.1 - 0.94 8.2 10.2 1.3 7.7 10.2 1.1 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 OAJ10472.1 - 0.95 7.8 31.5 1.4 7.2 31.5 1.2 1 0 0 1 1 1 0 Mpp10 protein Plasmodium_Vir PF05795.11 OAJ10472.1 - 1.7 8.0 10.9 2.7 7.3 10.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PTPRCAP PF15713.5 OAJ10472.1 - 1.7 8.9 30.1 0.26 11.6 25.4 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Zip PF02535.22 OAJ10472.1 - 2 7.6 7.5 2.5 7.2 7.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 OAJ10472.1 - 2.2 7.7 13.5 2.2 7.7 12.4 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CDC27 PF09507.10 OAJ10472.1 - 2.4 7.5 25.3 0.18 11.2 20.6 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF2151 PF10221.9 OAJ10472.1 - 2.5 6.6 7.6 3 6.3 7.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FancD2 PF14631.6 OAJ10472.1 - 2.6 5.3 6.3 3.2 5.0 6.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MRNIP PF15749.5 OAJ10472.1 - 2.6 8.8 10.8 7.6 7.3 10.8 1.8 1 0 0 1 1 1 0 MRN-interacting protein CPSF100_C PF13299.6 OAJ10472.1 - 8.8 6.5 13.2 18 5.4 13.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RVT_1 PF00078.27 OAJ10477.1 - 0.0015 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ10477.1 - 0.014 15.2 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like CBP_BcsR PF10945.8 OAJ10477.1 - 0.071 12.6 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR HEAT_EZ PF13513.6 OAJ10479.1 - 6.9e-11 42.4 14.2 0.025 15.1 0.3 6.3 3 1 3 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 OAJ10479.1 - 0.00034 20.9 17.0 0.021 15.2 3.0 5.4 4 1 2 6 6 6 3 HEAT repeats RIX1 PF08167.12 OAJ10479.1 - 0.00041 20.1 1.6 0.75 9.5 0.1 3.2 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis HEAT PF02985.22 OAJ10479.1 - 0.0013 18.8 15.8 19 5.9 0.0 8.3 9 0 0 9 9 9 1 HEAT repeat ParcG PF10274.9 OAJ10479.1 - 0.0054 16.9 0.0 0.08 13.0 0.0 2.7 3 1 0 3 3 3 1 Parkin co-regulated protein Ecm29 PF13001.7 OAJ10479.1 - 0.0083 14.9 0.0 0.027 13.1 0.0 1.8 2 1 0 2 2 2 1 Proteasome stabiliser Phage_TAC_12 PF12363.8 OAJ10479.1 - 0.012 16.1 0.0 0.051 14.0 0.0 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DUF3385 PF11865.8 OAJ10479.1 - 0.12 12.3 0.0 2.2 8.2 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 OAJ10479.1 - 0.36 9.9 2.5 1.4 8.0 0.0 2.7 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal zf-CCHC_4 PF14392.6 OAJ10483.1 - 4.8 7.0 7.1 5.8 6.7 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle Phage_integrase PF00589.22 OAJ10485.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 OAJ10485.1 - 0.05 14.1 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 OAJ10485.1 - 0.068 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DNA_pol_viral_C PF00336.18 OAJ10485.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain zf-RRN7 PF11781.8 OAJ10489.1 - 1.3 8.8 4.8 0.33 10.7 1.2 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Tyrosinase PF00264.20 OAJ10490.1 - 2.3e-26 93.5 0.0 3.3e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Spt4 PF06093.13 OAJ10498.1 - 3.6e-29 100.7 0.1 4.1e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MIF4G_like PF09088.11 OAJ10499.1 - 2.6e-65 219.8 0.1 3.5e-64 216.1 0.0 2.6 3 0 0 3 3 3 1 MIF4G like MIF4G_like_2 PF09090.11 OAJ10499.1 - 9.1e-61 205.7 0.0 2.7e-60 204.1 0.0 1.9 1 1 0 1 1 1 1 MIF4G like DUF4407 PF14362.6 OAJ10499.1 - 0.54 9.6 4.6 1.1 8.6 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Skp1 PF01466.19 OAJ10500.1 - 4.1e-27 94.0 0.3 7.7e-27 93.2 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAJ10500.1 - 6.8e-19 67.8 0.0 1.5e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain RuvX PF03652.15 OAJ10508.1 - 0.014 15.8 0.4 0.026 14.9 0.4 1.5 1 0 0 1 1 1 0 Holliday junction resolvase RRN3 PF05327.11 OAJ10508.1 - 0.61 8.6 6.4 0.72 8.3 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4448 PF14610.6 OAJ10511.1 - 0.11 12.2 0.3 12 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TRAPP PF04051.16 OAJ10519.1 - 6.3e-32 110.3 0.0 1.8e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component YqfQ PF14181.6 OAJ10519.1 - 1.6 8.9 6.5 2.2 8.5 6.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein MCR_alpha PF02249.17 OAJ10519.1 - 9.2 6.7 7.1 18 5.8 7.1 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain RVT_1 PF00078.27 OAJ10520.1 - 5.1e-15 55.6 0.0 7.5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAJ10520.1 - 1.8e-08 34.7 0.0 5.4e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 RNase H RVT_1 PF00078.27 OAJ10521.1 - 3.8e-07 29.9 0.0 6.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PMEI PF04043.15 OAJ10523.1 - 0.3 11.4 13.6 0.28 11.5 10.9 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Glyco_hydro_9 PF00759.19 OAJ10523.1 - 0.88 8.9 14.0 1.2 8.5 14.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Draxin PF15550.6 OAJ10523.1 - 2.3 8.0 5.7 3.2 7.5 5.7 1.3 1 0 0 1 1 1 0 Draxin FAM199X PF15814.5 OAJ10523.1 - 8.7 5.3 14.2 14 4.6 14.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X ApbA PF02558.16 OAJ10524.1 - 5.8e-27 94.2 0.0 9.3e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAJ10524.1 - 6.2e-27 94.3 0.0 1.6e-26 92.9 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_3 PF01494.19 OAJ10524.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 OAJ10529.1 - 4.3e-75 252.2 0.0 6.2e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 OAJ10529.1 - 1.9e-12 47.7 0.2 5.1e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 OAJ10529.1 - 2e-05 25.1 0.0 0.00012 22.6 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 OAJ10529.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ10529.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAJ10529.1 - 0.063 13.7 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pox_Ag35 PF03286.14 OAJ10536.1 - 0.028 14.2 9.7 0.063 13.1 9.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5419 PF17441.2 OAJ10536.1 - 0.09 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5419) GEMIN8 PF15348.6 OAJ10536.1 - 0.17 12.2 3.8 0.37 11.1 3.8 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DNA_pol_phi PF04931.13 OAJ10536.1 - 0.47 8.5 7.4 0.75 7.8 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 OAJ10536.1 - 1.1 9.7 5.7 2.8 8.4 5.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S64 PF08192.11 OAJ10536.1 - 4.4 5.7 12.6 6.2 5.2 12.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Transposase_21 PF02992.14 OAJ10538.1 - 3e-08 33.2 0.1 5.4e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 RT_RNaseH PF17917.1 OAJ10543.1 - 1.5e-37 128.1 0.1 2.7e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10543.1 - 1.9e-33 114.5 0.0 6e-33 112.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10543.1 - 8.5e-31 107.2 0.1 1.4e-30 106.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10543.1 - 1.3e-20 73.3 0.0 3.7e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10543.1 - 5.4e-14 52.4 0.0 8.4e-13 48.6 0.0 3.0 4 0 0 4 4 4 1 Integrase core domain Retrotrans_gag PF03732.17 OAJ10543.1 - 6.3e-09 36.0 0.8 3.4e-08 33.6 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ10543.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 OAJ10543.1 - 0.00072 20.1 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ10543.1 - 0.001 19.3 0.0 0.0051 17.0 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 OAJ10543.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ10543.1 - 0.0059 17.1 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 OAJ10543.1 - 0.029 14.2 0.0 2.8 7.8 0.0 2.9 2 0 0 2 2 2 0 Integrase core domain DEAD PF00270.29 OAJ10549.1 - 1.7e-39 135.4 0.0 2.8e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ10549.1 - 3.3e-24 85.4 0.0 9.1e-24 84.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10549.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MtlR PF05068.12 OAJ10549.1 - 0.15 12.0 0.3 0.3 11.1 0.1 1.5 2 0 0 2 2 2 0 Mannitol repressor DNA_pol_E_B PF04042.16 OAJ10550.1 - 7.6e-30 103.8 0.5 1.1e-29 103.3 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 OAJ10550.1 - 5.1e-18 65.9 0.0 1e-17 64.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal GMC_oxred_N PF00732.19 OAJ10551.1 - 1.1e-50 172.7 0.9 3.1e-49 167.9 0.9 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ10551.1 - 1.7e-28 100.0 0.0 3.1e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ10551.1 - 2.8e-06 26.7 0.1 0.00016 20.9 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ10551.1 - 8.6e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ10551.1 - 1.4e-05 25.2 0.3 3.8e-05 23.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ10551.1 - 0.00096 18.5 0.4 0.0028 16.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ10551.1 - 0.0056 16.3 0.3 0.0056 16.3 0.3 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ10551.1 - 0.0075 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAJ10551.1 - 0.0094 15.2 0.1 0.024 13.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAJ10551.1 - 0.035 12.8 0.1 0.083 11.6 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 OAJ10551.1 - 0.044 14.0 0.2 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAJ10551.1 - 0.051 12.8 1.2 0.19 11.0 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ10551.1 - 0.12 12.4 0.3 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding TPR_1 PF00515.28 OAJ10559.1 - 2.2e-28 96.9 10.9 1.9e-05 24.2 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ10559.1 - 8.7e-26 87.9 15.0 5e-05 23.2 0.0 9.6 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ10559.1 - 2.1e-25 86.7 16.5 2.5e-05 24.1 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC8 PF04049.13 OAJ10559.1 - 6.2e-17 62.0 1.2 3e-16 59.8 1.2 2.1 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 OAJ10559.1 - 5.3e-15 54.8 26.3 0.00021 21.8 0.1 9.1 7 4 3 10 10 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ10559.1 - 1.3e-13 50.3 6.1 0.023 15.1 0.0 7.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ10559.1 - 3.6e-13 48.9 1.1 0.00041 20.0 0.0 4.8 5 0 0 5 5 5 3 TPR repeat ANAPC3 PF12895.7 OAJ10559.1 - 1.8e-11 44.1 9.5 0.00014 22.0 0.3 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAJ10559.1 - 5.6e-10 39.6 7.9 0.5 10.9 0.0 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ10559.1 - 1.2e-09 38.6 16.6 0.00054 20.5 0.0 6.8 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ10559.1 - 2.3e-09 37.4 15.0 0.00057 20.1 1.3 7.4 6 4 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ10559.1 - 9.4e-09 34.7 10.8 0.00035 20.4 0.1 5.8 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ10559.1 - 9.2e-08 32.1 3.0 0.68 10.1 0.0 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ10559.1 - 1.6e-06 27.6 4.0 0.13 11.4 0.0 4.9 1 1 3 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 OAJ10559.1 - 9.3e-05 21.6 0.0 0.045 12.8 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 OAJ10559.1 - 0.00018 22.0 17.7 7.3 7.5 0.0 9.3 10 1 1 11 11 10 1 Tetratricopeptide repeat PPR PF01535.20 OAJ10559.1 - 0.067 13.5 0.9 17 6.0 0.0 4.0 5 0 0 5 5 4 0 PPR repeat TPR_10 PF13374.6 OAJ10559.1 - 0.11 12.4 18.1 0.27 11.2 0.1 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat RPN7 PF10602.9 OAJ10559.1 - 0.11 12.2 0.2 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 SNAP PF14938.6 OAJ10559.1 - 0.23 10.9 4.2 1.3 8.4 0.1 3.2 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP SNF2_N PF00176.23 OAJ10560.1 - 5.6e-55 186.5 0.1 8.7e-55 185.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ10560.1 - 9.5e-15 54.9 0.0 2.1e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10560.1 - 8.6e-10 38.9 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ10560.1 - 1.9e-06 27.3 0.0 3.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OAJ10560.1 - 3.2e-06 27.0 0.3 9.8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAJ10560.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 OAJ10560.1 - 0.0056 15.6 0.0 0.045 12.6 0.0 2.2 2 1 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Calcipressin PF04847.12 OAJ10560.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Calcipressin TusA PF01206.17 OAJ10560.1 - 0.096 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Sulfurtransferase TusA Response_reg PF00072.24 OAJ10564.1 - 1.9e-21 76.3 0.0 9.4e-16 58.0 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain DUF89 PF01937.19 OAJ10565.1 - 1e-111 373.4 0.0 1.1e-111 373.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Bacillus_HBL PF05791.11 OAJ10574.1 - 0.025 14.4 0.2 0.032 14.1 0.2 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RVT_2 PF07727.14 OAJ10575.1 - 5.1e-60 203.1 0.0 8.1e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAJ10575.1 - 1.4e-21 76.6 0.1 2.4e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ10575.1 - 3.2e-16 59.6 0.0 1.2e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10575.1 - 1.6e-06 27.9 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 OAJ10575.1 - 0.032 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) rve_3 PF13683.6 OAJ10575.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.23 OAJ10575.1 - 1.7 8.8 3.4 4.1 7.6 3.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Response_reg PF00072.24 OAJ10584.1 - 9.2e-08 32.2 0.0 3.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain DAAD PF18752.1 OAJ10584.1 - 2.6 7.8 5.3 8.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase E3_binding PF02817.17 OAJ10585.1 - 2.9e-07 30.7 0.2 5.9e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 e3 binding domain Peptidase_C65 PF10275.9 OAJ10586.1 - 3.6e-62 210.0 0.0 4.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 OAJ10586.1 - 0.0055 17.2 0.0 0.086 13.3 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease TPMT PF05724.11 OAJ10587.1 - 1.6e-33 116.2 0.0 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OAJ10587.1 - 6.3e-10 39.6 0.0 9.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ10587.1 - 1.6e-08 34.5 0.0 2.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ10587.1 - 1.7e-08 35.0 0.0 2.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ10587.1 - 6.3e-06 26.9 0.0 1.7e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ10587.1 - 8.5e-06 25.7 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NPV_P10 PF05531.12 OAJ10595.1 - 1.1 9.7 11.3 1.2 9.6 0.0 4.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 OAJ10595.1 - 5.3 7.4 8.2 22 5.4 0.7 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TRAUB PF08164.12 OAJ10596.1 - 2.4e-23 82.4 0.0 1.8e-22 79.7 0.0 2.5 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OAJ10596.1 - 8.7e-09 36.2 4.5 8.7e-09 36.2 4.5 2.8 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor Pkinase PF00069.25 OAJ10597.1 - 3e-71 239.9 0.0 3.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10597.1 - 1.9e-34 119.1 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10597.1 - 0.025 13.9 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAJ10597.1 - 0.029 13.3 0.0 0.33 9.8 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain zf-CCHC_3 PF13917.6 OAJ10603.1 - 0.00034 20.5 1.8 0.00086 19.2 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ10603.1 - 0.0012 18.4 4.2 0.0029 17.3 3.4 2.0 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OAJ10603.1 - 0.0027 17.7 1.5 0.0045 17.0 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ10603.1 - 0.021 14.6 0.9 0.033 14.0 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 OAJ10605.1 - 1.7e-71 240.7 0.0 3e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10605.1 - 3.4e-19 69.2 1.0 8.3e-19 67.9 0.1 2.3 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10605.1 - 1.1e-05 25.1 0.0 3.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ10605.1 - 0.00039 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain GMC_oxred_N PF00732.19 OAJ10612.1 - 1.3e-49 169.2 0.0 1.7e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ10612.1 - 7.5e-35 120.6 0.1 1.3e-34 119.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAJ10612.1 - 0.00017 21.0 0.3 0.12 11.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ10612.1 - 0.00017 20.8 0.7 0.0082 15.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ10612.1 - 0.0002 21.5 0.7 0.00051 20.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAJ10612.1 - 0.00046 19.4 0.2 0.00069 18.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAJ10612.1 - 0.0038 16.5 0.1 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ10612.1 - 0.0049 16.5 0.5 0.012 15.2 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase COR PF16095.5 OAJ10612.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain FAD_binding_3 PF01494.19 OAJ10612.1 - 0.072 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAJ10612.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MLTD_N PF06474.12 OAJ10613.1 - 4.9 7.4 5.8 13 6.0 5.8 1.7 1 0 0 1 1 1 0 MltD lipid attachment motif RVT_1 PF00078.27 OAJ10614.1 - 1.5e-32 113.0 0.0 2.8e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Motile_Sperm PF00635.26 OAJ10617.1 - 5.1e-25 87.4 0.1 9.9e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 OAJ10617.1 - 0.0016 18.6 0.1 0.0051 17.0 0.1 1.9 1 1 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 OAJ10617.1 - 0.009 16.2 0.6 0.017 15.3 0.1 1.7 2 0 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Tcp11 PF05794.13 OAJ10618.1 - 3.3e-91 306.6 0.0 4.7e-90 302.8 0.0 2.4 1 1 0 1 1 1 1 T-complex protein 11 DHHC PF01529.20 OAJ10630.1 - 5.2e-30 104.3 9.0 5.2e-30 104.3 9.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.6 OAJ10630.1 - 0.22 11.4 11.1 0.14 12.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) DUF2339 PF10101.9 OAJ10630.1 - 6.8 5.2 9.3 0.56 8.7 3.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) DEAD PF00270.29 OAJ10636.1 - 1.3e-11 44.6 0.0 3.7e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ10636.1 - 1.2e-06 28.9 0.0 5.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10636.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1943 PF09172.11 OAJ10638.1 - 0.041 13.1 0.5 0.052 12.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Tox-PL-2 PF15643.6 OAJ10638.1 - 0.056 13.6 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 Papain fold toxin 2 Edc3_linker PF16598.5 OAJ10638.1 - 0.25 12.0 9.0 0.5 11.1 9.0 1.5 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 SOBP PF15279.6 OAJ10638.1 - 0.92 10.1 7.6 1.2 9.7 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2796 PF10986.8 OAJ10638.1 - 5.5 6.9 14.1 72 3.3 13.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) DUF3446 PF11928.8 OAJ10640.1 - 0.046 14.0 2.6 0.12 12.7 2.6 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Cupin_8 PF13621.6 OAJ10654.1 - 1.2e-41 143.2 3.0 1.4e-22 80.7 0.0 5.0 4 1 0 4 4 4 2 Cupin-like domain ANAPC15 PF15243.6 OAJ10654.1 - 0.0038 17.6 5.7 0.0038 17.6 5.7 9.6 7 2 3 10 10 10 1 Anaphase-promoting complex subunit 15 VPS9 PF02204.18 OAJ10655.1 - 1.5e-18 66.9 0.0 2.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Transposase_21 PF02992.14 OAJ10663.1 - 1.9e-11 43.7 0.3 5.9e-11 42.0 0.0 1.9 3 0 0 3 3 3 1 Transposase family tnp2 SR-25 PF10500.9 OAJ10665.1 - 0.0055 16.4 16.7 0.0055 16.4 16.7 2.5 2 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein PIF1 PF05970.14 OAJ10671.1 - 1.6e-17 63.8 0.0 2.7e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ10671.1 - 1.5e-16 61.2 0.0 4.2e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ10671.1 - 1.1e-14 54.6 0.2 1.1e-14 54.6 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ10671.1 - 1.5e-10 41.6 0.0 3.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ10671.1 - 0.0041 17.5 0.3 0.017 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ10671.1 - 0.012 15.9 0.0 0.045 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 OAJ10671.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Helicase ResIII PF04851.15 OAJ10671.1 - 0.074 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OAJ10671.1 - 0.14 12.2 0.3 0.86 9.6 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 OAJ10671.1 - 0.16 12.1 0.0 0.56 10.3 0.0 1.9 1 0 0 1 1 1 0 Torsin Osteopontin PF00865.18 OAJ10671.1 - 0.35 10.3 10.2 0.79 9.2 10.2 1.5 1 0 0 1 1 1 0 Osteopontin PAP_central PF04928.17 OAJ10685.1 - 1.2e-97 325.8 0.0 1.7e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAJ10685.1 - 3.9e-50 169.8 0.0 7.9e-50 168.8 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAJ10685.1 - 3e-11 43.4 0.0 7.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ10685.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Arrestin_N PF00339.29 OAJ10686.1 - 1.5e-05 25.1 0.0 4.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4766 PF15973.5 OAJ10686.1 - 0.026 15.1 1.4 0.026 15.1 1.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4766) YABBY PF04690.13 OAJ10687.1 - 1.9e-08 35.1 0.9 2.2e-08 34.9 0.9 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 OAJ10687.1 - 6.9e-05 23.2 0.5 9e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box MAGI_u5 PF16666.5 OAJ10687.1 - 0.0033 17.6 2.5 0.0037 17.4 2.5 1.2 1 0 0 1 1 1 1 Unstructured region on MAGI Ccdc124 PF06244.12 OAJ10687.1 - 0.0048 17.4 2.3 0.006 17.1 2.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 OAJ10687.1 - 0.0075 16.8 0.3 0.01 16.4 0.3 1.2 1 0 0 1 1 1 1 HMG-box domain Ribosomal_L34 PF00468.17 OAJ10692.1 - 3.5e-19 68.5 9.6 5.3e-19 67.9 9.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 SNF2_N PF00176.23 OAJ10693.1 - 8.2e-40 136.6 0.0 1.5e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ10693.1 - 1.9e-18 66.8 0.0 6e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10693.1 - 7.9e-07 29.2 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ10693.1 - 2.9e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAJ10693.1 - 8.2e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase GDA1_CD39 PF01150.17 OAJ10694.1 - 5.4e-102 341.6 0.0 7.4e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CBX7_C PF17218.3 OAJ10694.1 - 2.8 7.8 4.4 5.6 6.8 4.4 1.5 1 0 0 1 1 1 0 CBX family C-terminal motif Pkinase_Tyr PF07714.17 OAJ10699.1 - 2.4e-08 33.6 0.0 2.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ10699.1 - 1.3e-06 28.0 0.0 5.6e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain EI24 PF07264.11 OAJ10706.1 - 0.00032 21.0 8.7 0.00056 20.2 8.7 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Amino_oxidase PF01593.24 OAJ10707.1 - 5.3e-56 190.8 0.2 6.7e-56 190.5 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ10707.1 - 8.1e-12 45.2 1.0 2e-11 43.9 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAJ10707.1 - 1.4e-06 27.3 1.3 0.00064 18.5 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OAJ10707.1 - 3.6e-06 26.3 1.3 6.1e-06 25.6 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAJ10707.1 - 1.1e-05 25.2 2.6 6.2e-05 22.7 2.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ10707.1 - 3.7e-05 24.2 0.2 0.00053 20.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ10707.1 - 0.00014 21.3 0.2 0.00025 20.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ10707.1 - 0.00015 21.1 0.8 0.0011 18.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ10707.1 - 0.00036 20.0 1.3 0.00056 19.4 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ10707.1 - 0.00085 18.6 2.4 0.0011 18.3 1.1 1.9 2 1 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAJ10707.1 - 0.0016 17.8 2.8 0.03 13.6 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ10707.1 - 0.0022 18.0 0.6 0.59 10.1 0.2 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAJ10707.1 - 0.0038 16.3 0.1 1.7 7.6 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAJ10707.1 - 0.069 12.4 0.6 0.13 11.6 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAJ10707.1 - 0.076 12.1 1.4 0.3 10.1 0.7 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Diphthamide_syn PF01866.17 OAJ10709.1 - 3.8e-84 282.7 0.0 9.8e-47 159.8 0.0 3.2 2 1 0 2 2 2 2 Putative diphthamide synthesis protein Lyase_aromatic PF00221.19 OAJ10713.1 - 5.3e-151 503.4 6.2 6.9e-151 503.0 6.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase HTH_Tnp_Tc3_2 PF01498.18 OAJ10714.1 - 9.4e-17 61.0 7.3 9.4e-17 61.0 7.3 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 OAJ10714.1 - 1.1e-12 47.9 0.0 2.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ10714.1 - 0.00026 21.5 2.7 0.00026 21.5 2.7 3.2 3 1 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 OAJ10714.1 - 0.00098 19.1 2.4 0.006 16.6 0.3 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_21 PF13276.6 OAJ10714.1 - 0.0013 18.8 3.3 0.0018 18.4 1.7 2.1 2 0 0 2 2 2 1 HTH-like domain HTH_23 PF13384.6 OAJ10714.1 - 0.018 14.8 0.8 0.86 9.5 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 OAJ10714.1 - 0.02 13.9 0.3 0.65 8.9 0.1 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain DHDPS PF00701.22 OAJ10714.1 - 0.057 12.1 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family DUF668 PF05003.12 OAJ10714.1 - 0.064 13.7 1.0 0.2 12.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF668) G-patch PF01585.23 OAJ10715.1 - 2.9e-14 52.7 0.7 2.9e-14 52.7 0.7 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ10715.1 - 0.00017 21.6 0.3 0.00017 21.6 0.3 3.3 3 1 0 3 3 3 1 G-patch domain CDC45 PF02724.14 OAJ10715.1 - 0.0028 16.0 7.6 0.0028 16.0 7.6 2.1 2 0 0 2 2 2 1 CDC45-like protein DUF3340 PF11818.8 OAJ10715.1 - 0.42 10.8 17.2 0.44 10.7 7.7 2.4 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) EOS1 PF12326.8 OAJ10715.1 - 2.7 7.9 5.5 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 N-glycosylation protein NARP1 PF12569.8 OAJ10715.1 - 8.2 5.2 20.9 0.58 9.0 4.1 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RT_RNaseH PF17917.1 OAJ10724.1 - 2e-28 98.8 0.0 4.9e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10724.1 - 7.8e-19 67.6 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10724.1 - 6.9e-17 61.3 0.0 2.3e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ10724.1 - 3.4e-15 56.2 0.5 6.4e-15 55.3 0.5 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10724.1 - 3.5e-11 43.3 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 OAJ10724.1 - 2.6e-08 33.7 0.0 5.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ10724.1 - 1.2e-05 25.7 0.0 3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ10724.1 - 4e-05 24.2 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 OAJ10724.1 - 0.00032 20.7 2.6 0.00032 20.7 2.6 1.9 2 0 0 2 2 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAJ10724.1 - 0.00081 19.6 0.1 0.0035 17.6 0.1 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.10 OAJ10724.1 - 0.0043 17.2 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 OAJ10724.1 - 0.0081 16.1 0.2 0.025 14.5 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_2 PF13696.6 OAJ10724.1 - 0.067 13.0 2.6 0.15 11.9 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Zn_clus PF00172.18 OAJ10727.1 - 3.4e-08 33.5 8.3 5.4e-08 32.8 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ10727.1 - 9.6e-06 24.8 0.3 3.3e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fmp27_SW PF10305.9 OAJ10727.1 - 0.12 13.1 2.2 0.55 11.0 1.4 2.5 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain HD_3 PF13023.6 OAJ10728.1 - 1.1e-39 136.1 0.0 1.8e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAJ10728.1 - 1.1e-06 28.5 0.6 3e-06 27.1 0.6 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OAJ10728.1 - 0.00063 20.0 0.1 0.0015 18.7 0.1 1.6 1 0 0 1 1 1 1 HD domain Antirestrict PF03230.13 OAJ10728.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Antirestriction protein DUF2340 PF10209.9 OAJ10732.1 - 1.4e-46 157.9 0.0 1.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) PhyH PF05721.13 OAJ10733.1 - 1.1e-41 143.5 0.0 1.7e-41 142.8 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRP7 PF12923.7 OAJ10734.1 - 7.1e-23 81.0 0.3 7.1e-23 81.0 0.3 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAJ10734.1 - 3.3e-13 49.8 1.6 3.4e-12 46.5 1.6 2.1 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 OAJ10734.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH_9 PF15410.6 OAJ10735.1 - 1.8e-29 102.5 0.0 3.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 OAJ10735.1 - 4.3e-28 98.2 0.1 9.2e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAJ10735.1 - 0.00027 21.4 0.0 0.00071 20.1 0.0 1.7 1 1 0 1 1 1 1 PH domain Hemerythrin PF01814.23 OAJ10741.1 - 2.8e-12 47.4 5.7 2.7e-10 41.0 3.3 2.0 1 1 0 2 2 2 2 Hemerythrin HHE cation binding domain Sod_Fe_C PF02777.18 OAJ10742.1 - 2.9e-17 62.7 0.0 5e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ10742.1 - 0.04 14.4 0.0 0.065 13.7 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain LST1 PF05083.13 OAJ10742.1 - 0.12 12.7 0.7 3 8.2 0.1 2.3 2 0 0 2 2 2 0 LST-1 protein TMEM70 PF06979.12 OAJ10743.1 - 0.00046 20.6 0.1 0.00077 19.9 0.1 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex BTB PF00651.31 OAJ10744.1 - 5e-07 29.9 0.0 9.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_11 PF08241.12 OAJ10750.1 - 6.5e-08 33.1 0.1 5.3e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ10750.1 - 1.1e-07 32.4 0.0 3.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ10750.1 - 4.1e-07 30.0 0.0 6.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ10750.1 - 1.2e-06 29.1 0.1 1.3e-05 25.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ10750.1 - 0.0011 20.0 0.1 0.02 15.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.17 OAJ10750.1 - 0.014 15.1 0.0 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 OAJ10750.1 - 0.015 15.1 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ10750.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RisS_PPD PF16524.5 OAJ10750.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Swi6_N PF18530.1 OAJ10750.1 - 0.14 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Swi6 N-terminal domain MFS_1 PF07690.16 OAJ10751.1 - 1.5e-28 99.7 13.1 1.5e-28 99.7 13.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAJ10751.1 - 5.4e-07 29.2 3.8 1.9e-06 27.5 1.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OAJ10751.1 - 8.2e-07 28.2 4.6 2.6e-06 26.6 4.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ10751.1 - 0.0054 15.2 0.9 0.0083 14.6 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OAJ10751.1 - 0.0076 15.1 0.0 0.018 13.9 0.0 1.9 1 1 0 1 1 1 1 MFS_1 like family ApbA_C PF08546.11 OAJ10753.1 - 3.4e-24 85.4 0.0 1.3e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAJ10753.1 - 5.5e-20 71.6 0.0 8.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OAJ10753.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 OAJ10753.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ10753.1 - 0.058 13.7 0.2 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 OAJ10753.1 - 0.087 12.4 0.3 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 OAJ10753.1 - 0.13 11.8 0.2 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAJ10753.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LIFR_N PF18207.1 OAJ10753.1 - 0.21 12.0 0.1 0.5 10.8 0.1 1.6 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain Tyosinase_C PF18132.1 OAJ10754.1 - 0.052 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Tyosinase C-terminal domain Apolipoprotein PF01442.18 OAJ10758.1 - 0.061 13.2 2.1 0.22 11.4 0.5 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain HalX PF08663.10 OAJ10758.1 - 0.17 12.2 2.7 0.86 10.0 2.7 2.1 1 1 0 1 1 1 0 HalX domain P66_CC PF16563.5 OAJ10758.1 - 0.21 11.2 1.7 0.38 10.4 1.7 1.4 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 RVT_1 PF00078.27 OAJ10759.1 - 1.6e-21 76.9 0.0 3.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10759.1 - 2.1e-14 53.3 0.1 4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ10759.1 - 1.2e-12 47.7 0.0 2.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10759.1 - 1.6e-11 44.4 0.0 4.8e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ10759.1 - 0.0079 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ10759.1 - 0.0079 16.4 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RNase_P_Rpp14 PF01900.19 OAJ10763.1 - 1.6e-25 89.3 0.0 2.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Cellulase PF00150.18 OAJ10764.1 - 1.2e-13 51.2 0.5 1.8e-13 50.6 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_17 PF13431.6 OAJ10765.1 - 1e-08 34.9 0.9 0.0087 16.4 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ10765.1 - 2.7e-08 34.3 21.7 0.0028 18.3 1.6 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ10765.1 - 3.1e-07 30.0 7.1 0.13 12.5 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ10765.1 - 3.2e-07 30.0 0.5 0.09 13.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ10765.1 - 1.1e-05 25.6 1.9 0.0033 17.6 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAJ10765.1 - 1.2e-05 25.7 22.6 0.037 14.9 0.7 7.8 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ10765.1 - 0.00031 20.4 1.9 2.3 8.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ10765.1 - 0.0088 16.5 16.3 0.071 13.6 0.3 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ10765.1 - 0.021 14.5 0.8 4.9 6.9 0.1 4.0 3 1 1 4 4 4 0 TPR repeat ChAPs PF09295.10 OAJ10765.1 - 0.83 8.6 5.6 1.4 7.8 0.5 2.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 OAJ10765.1 - 1.3 9.2 22.2 1.7 8.9 0.8 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ10765.1 - 9.1 6.6 7.4 22 5.4 0.0 4.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 OAJ10772.1 - 0.11 12.6 0.2 0.2 11.7 0.0 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone DDE_Tnp_4 PF13359.6 OAJ10773.1 - 4.8e-25 88.1 0.0 7.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ10773.1 - 7e-06 25.8 0.3 0.015 15.0 0.0 2.8 3 0 0 3 3 3 2 Transposase DDE domain Plant_tran PF04827.14 OAJ10773.1 - 0.00021 20.9 0.0 0.0028 17.3 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein Glyco_hydro_45 PF02015.16 OAJ10780.1 - 4e-49 167.4 5.1 5e-49 167.1 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Retrotran_gag_2 PF14223.6 OAJ10781.1 - 3.5e-05 23.5 0.0 3.9e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Lipase_3 PF01764.25 OAJ10783.1 - 4.5e-20 72.0 0.0 6.5e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ10783.1 - 0.0065 17.1 2.0 0.01 16.5 0.5 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ10783.1 - 0.0091 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAJ10783.1 - 0.03 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold gag_pre-integrs PF13976.6 OAJ10784.1 - 0.0076 16.1 0.1 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 OAJ10784.1 - 0.029 14.1 0.9 0.077 12.7 0.9 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 OAJ10784.1 - 0.035 14.2 2.3 0.035 14.2 2.3 1.9 2 0 0 2 2 2 0 Zinc knuckle RVP PF00077.20 OAJ10784.1 - 0.073 13.4 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_2 PF07727.14 OAJ10785.1 - 9.6e-46 156.4 0.0 9.8e-26 90.9 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) An_peroxidase PF03098.15 OAJ10796.1 - 5.6e-38 130.8 0.0 7.1e-24 84.3 0.2 3.9 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAJ10796.1 - 6.4e-14 51.5 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 RT_RNaseH_2 PF17919.1 OAJ10797.1 - 8e-20 70.7 0.3 2.3e-12 46.8 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10797.1 - 7.7e-17 61.2 0.0 2e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ10797.1 - 8.3e-16 58.2 0.0 1.8e-10 41.0 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10797.1 - 4.8e-13 49.3 0.0 2.2e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Cation_ATPase_C PF00689.21 OAJ10798.1 - 4.9e-37 127.4 2.5 6.9e-37 126.9 2.5 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ10798.1 - 4e-15 56.7 0.1 1.4e-06 28.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FHA PF00498.26 OAJ10806.1 - 0.075 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 FHA domain Transposase_21 PF02992.14 OAJ10807.1 - 1.5e-09 37.4 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 CDC45 PF02724.14 OAJ10807.1 - 0.56 8.4 5.5 0.71 8.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sulfate_transp PF00916.20 OAJ10813.1 - 0.00099 18.0 0.4 0.0014 17.4 0.4 1.2 1 0 0 1 1 1 1 Sulfate permease family DDE_Tnp_4 PF13359.6 OAJ10819.1 - 7e-08 32.3 0.2 9.6e-08 31.9 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ10819.1 - 3.7e-05 23.4 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein Nucleoside_tran PF01733.18 OAJ10819.1 - 0.084 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter TMEM117 PF15113.6 OAJ10819.1 - 0.26 10.2 0.0 0.34 9.8 0.0 1.1 1 0 0 1 1 1 0 TMEM117 protein family RT_RNaseH_2 PF17919.1 OAJ10820.1 - 1.7e-29 101.8 0.0 3.9e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10820.1 - 2.7e-26 91.9 0.0 6.7e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10820.1 - 1.2e-20 74.0 0.0 2.4e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10820.1 - 2.8e-14 53.3 0.0 1e-13 51.5 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ10820.1 - 1.9e-08 34.3 0.2 4.6e-08 33.0 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Myb_DNA-bind_3 PF12776.7 OAJ10821.1 - 0.024 15.6 0.1 0.048 14.6 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Phage_integrase PF00589.22 OAJ10828.1 - 1.4e-16 60.7 0.1 1.7e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Phage integrase family SNARE PF05739.19 OAJ10829.1 - 0.11 12.5 0.3 0.11 12.5 0.3 1.9 2 0 0 2 2 2 0 SNARE domain CD225 PF04505.12 OAJ10829.1 - 0.55 10.4 3.7 1.3 9.2 3.7 1.8 1 1 0 1 1 1 0 Interferon-induced transmembrane protein NAC PF01849.18 OAJ10837.1 - 3.6e-21 74.9 0.0 6.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 NAC domain Glyco_hydro_15 PF00723.21 OAJ10838.1 - 1.4e-79 268.0 0.1 1.9e-79 267.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.25 OAJ10839.1 - 7e-67 225.6 0.0 8.6e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10839.1 - 3.1e-31 108.6 0.0 4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ10839.1 - 1.3e-05 24.3 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ10839.1 - 0.00073 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ10839.1 - 0.0022 17.4 0.1 0.005 16.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ10839.1 - 0.013 14.9 0.0 0.14 11.4 0.0 2.0 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 OAJ10839.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAJ10839.1 - 0.045 13.4 0.1 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 RIO1 family ORC_WH_C PF18137.1 OAJ10846.1 - 3.8e-25 88.6 2.7 5.7e-25 88.0 0.0 2.6 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 OAJ10846.1 - 1.6e-12 47.2 10.0 1.9e-12 47.0 3.1 2.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus CCDC-167 PF15188.6 OAJ10846.1 - 3.7 8.0 4.7 1.2 9.5 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 F-box-like PF12937.7 OAJ10847.1 - 5.6e-05 22.9 0.3 0.00017 21.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAJ10847.1 - 0.024 14.7 4.4 34 4.8 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeat DDE_1 PF03184.19 OAJ10851.1 - 1.6e-29 102.8 0.0 2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 OAJ10853.1 - 8.3e-11 42.0 0.6 8.4e-10 38.8 0.6 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ10853.1 - 0.0002 21.3 0.6 0.00033 20.6 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OAJ10853.1 - 0.0091 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF4473 PF14747.6 OAJ10853.1 - 0.028 15.0 0.0 0.083 13.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) zf-C2H2_10 PF16588.5 OAJ10853.1 - 0.42 10.4 0.1 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 C2H2 zinc-finger RT_RNaseH PF17917.1 OAJ10854.1 - 1.9e-35 121.3 0.1 3.7e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10854.1 - 2.4e-28 98.1 0.0 5e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10854.1 - 2.4e-20 73.0 0.0 4.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10854.1 - 6e-19 68.4 0.0 1.5e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ10854.1 - 2e-17 63.0 0.3 4.6e-17 61.9 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ10854.1 - 7.1e-08 32.2 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 OAJ10854.1 - 3.6e-07 30.0 0.1 3.5e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OAJ10854.1 - 0.00052 20.6 0.0 0.002 18.7 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 OAJ10854.1 - 0.02 14.7 0.5 0.066 13.0 0.5 2.0 1 1 0 1 1 1 0 Integrase core domain ZZ PF00569.17 OAJ10860.1 - 4.8e-21 74.3 64.0 9e-08 31.8 2.6 5.9 6 0 0 6 6 6 4 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 OAJ10860.1 - 2.1e-19 70.1 0.5 9.4e-19 68.0 0.0 2.5 3 0 0 3 3 3 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 OAJ10860.1 - 0.00025 21.3 2.2 0.00025 21.3 2.2 5.9 6 0 0 6 6 6 3 C1 domain DUF2478 PF10649.9 OAJ10860.1 - 0.0069 16.0 0.4 0.019 14.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) Peptidase_S64 PF08192.11 OAJ10860.1 - 0.23 9.9 6.2 0.44 9.0 6.2 1.4 1 0 0 1 1 1 0 Peptidase family S64 PPR_2 PF13041.6 OAJ10861.1 - 0.00048 20.3 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family FTA4 PF13093.6 OAJ10861.1 - 0.018 15.0 0.9 0.039 13.8 0.9 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CAP_N PF01213.19 OAJ10861.1 - 2.1 7.8 8.3 7.1 6.0 0.4 3.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Nop PF01798.18 OAJ10862.1 - 2e-83 279.4 0.1 2e-83 279.4 0.1 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAJ10862.1 - 1.1e-16 60.9 0.0 6.4e-16 58.5 0.0 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Sporozoite_P67 PF05642.11 OAJ10862.1 - 0.024 12.7 12.1 0.035 12.2 12.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 OAJ10862.1 - 1.2 7.4 27.3 1.7 6.9 27.3 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ10862.1 - 1.9 8.5 32.1 3.4 7.7 32.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Spt5_N PF11942.8 OAJ10862.1 - 4 8.5 22.4 8.4 7.5 22.4 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SGT1 PF07093.11 OAJ10862.1 - 4.3 5.7 15.8 6.2 5.1 15.8 1.3 1 0 0 1 1 1 0 SGT1 protein Neur_chan_memb PF02932.16 OAJ10862.1 - 8.3 6.4 9.6 12 5.9 9.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA PF00004.29 OAJ10869.1 - 5.8e-44 149.7 0.0 1e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ10869.1 - 3.7e-10 39.4 0.1 8e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ10869.1 - 2.7e-08 34.1 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 OAJ10869.1 - 1.3e-07 31.4 0.5 2.9e-07 30.3 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ10869.1 - 2.3e-06 27.6 0.0 8.5e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ10869.1 - 6.6e-06 26.6 0.0 8.1e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ10869.1 - 6.7e-06 26.4 0.4 0.0055 17.0 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ10869.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ10869.1 - 0.0011 19.5 0.3 0.018 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 OAJ10869.1 - 0.0011 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAJ10869.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAJ10869.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 OAJ10869.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OAJ10869.1 - 0.0056 16.2 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 OAJ10869.1 - 0.0079 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAJ10869.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ10869.1 - 0.013 15.3 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAJ10869.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OAJ10869.1 - 0.018 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 OAJ10869.1 - 0.022 14.4 0.0 0.11 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 OAJ10869.1 - 0.031 13.5 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAJ10869.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ10869.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ10869.1 - 0.044 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 OAJ10869.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_25 PF13481.6 OAJ10869.1 - 0.066 12.8 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAJ10869.1 - 0.068 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APG6_N PF17675.1 OAJ10869.1 - 0.078 13.5 0.8 0.16 12.5 0.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region RILP PF11461.8 OAJ10869.1 - 0.095 12.9 1.2 0.2 11.9 1.2 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein Zeta_toxin PF06414.12 OAJ10869.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 OAJ10869.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAJ10869.1 - 0.14 12.5 0.1 0.49 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Amidase PF01425.21 OAJ10870.1 - 2.9e-79 267.1 0.0 1.2e-64 219.0 0.1 2.1 2 0 0 2 2 2 2 Amidase Minor_tail_Z PF06763.11 OAJ10870.1 - 0.096 12.5 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Aa_trans PF01490.18 OAJ10871.1 - 2e-57 194.7 7.3 9.1e-57 192.6 7.3 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAJ10871.1 - 0.001 18.2 6.0 0.001 18.2 6.0 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family YL1 PF05764.13 OAJ10871.1 - 2.8 8.0 10.5 2.8 8.0 8.9 1.8 1 1 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 OAJ10871.1 - 4.6 5.3 6.2 6.2 4.9 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 OAJ10871.1 - 5 6.6 5.7 8.2 5.9 5.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PIF1 PF05970.14 OAJ10885.1 - 3.6e-106 355.4 0.0 4.7e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ10885.1 - 1.2e-55 188.7 0.1 2.3e-55 187.8 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ10885.1 - 9.3e-09 35.3 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 OAJ10885.1 - 0.00011 20.3 0.0 0.00034 18.7 0.0 1.6 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 OAJ10885.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAJ10885.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 OAJ10885.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.12 OAJ10885.1 - 0.016 14.5 0.0 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 OAJ10885.1 - 0.026 13.4 0.0 0.08 11.8 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 OAJ10885.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF2791 PF10923.8 OAJ10885.1 - 0.16 10.8 0.1 0.28 10.0 0.1 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Glyco_hydro_43 PF04616.14 OAJ10894.1 - 3.3e-35 121.8 0.3 3.9e-35 121.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AP2 PF00847.20 OAJ10894.1 - 0.13 12.5 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 AP2 domain HeH PF12949.7 OAJ10901.1 - 0.0063 16.2 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain CHDCT2 PF08074.11 OAJ10902.1 - 0.17 12.0 1.0 0.23 11.6 1.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Spc7 PF08317.11 OAJ10902.1 - 0.27 10.1 2.6 0.33 9.8 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein OEP PF02321.18 OAJ10902.1 - 0.36 10.6 7.0 0.55 10.0 7.0 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein Collagen PF01391.18 OAJ10911.1 - 5.9e-06 25.9 15.9 9e-06 25.4 15.9 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ICMT PF04140.14 OAJ10912.1 - 7.7e-14 51.9 0.4 3e-13 50.0 0.4 1.8 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ10912.1 - 1.6e-06 28.4 0.7 5.9e-06 26.6 0.7 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 OAJ10912.1 - 0.1 11.3 0.0 5.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Dimer_Tnp_hAT PF05699.14 OAJ10919.1 - 1.6e-12 47.0 0.1 4.8e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 OAJ10919.1 - 0.025 14.6 0.6 0.16 12.0 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger Pkinase PF00069.25 OAJ10920.1 - 2.6e-43 148.3 0.0 5.1e-43 147.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10920.1 - 2e-19 69.9 0.0 3.3e-19 69.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10920.1 - 7.8e-08 32.0 0.0 1.9e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ10920.1 - 0.00066 19.7 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ10920.1 - 0.0043 16.7 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAJ10920.1 - 0.053 12.9 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAJ10920.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase YukC PF10140.9 OAJ10920.1 - 0.22 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RVT_2 PF07727.14 OAJ10921.1 - 1.4e-60 205.0 0.0 1.8e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10921.1 - 1.7e-11 44.4 0.4 7.4e-11 42.3 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10921.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_3 PF13456.6 OAJ10921.1 - 0.092 12.6 4.3 0.71 9.7 2.7 2.7 2 1 0 2 2 2 0 Reverse transcriptase-like rve_3 PF13683.6 OAJ10921.1 - 0.18 11.6 1.4 0.5 10.2 0.0 2.4 3 0 0 3 3 3 0 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ10922.1 - 1.1e-16 60.8 0.2 1.5e-16 60.3 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type IFT46_B_C PF12317.8 OAJ10922.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal zf-CCHC PF00098.23 OAJ10922.1 - 0.26 11.4 2.3 0.51 10.5 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L18A PF01775.17 OAJ10931.1 - 1.4e-52 176.9 0.2 1.7e-52 176.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A ubiquitin PF00240.23 OAJ10932.1 - 4.5e-34 116.0 0.7 6e-34 115.6 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OAJ10932.1 - 4.6e-29 100.1 9.0 7e-29 99.5 9.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OAJ10932.1 - 3.5e-16 58.8 0.8 4.6e-16 58.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ10932.1 - 2e-05 25.0 0.2 7.4e-05 23.1 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ10932.1 - 0.0041 17.0 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ10932.1 - 0.0056 17.0 0.1 0.0091 16.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ10932.1 - 0.0074 16.4 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ10932.1 - 0.014 15.9 0.1 0.023 15.2 0.1 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ10932.1 - 0.015 15.3 1.1 4.4 7.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Pkinase PF00069.25 OAJ10933.1 - 5.8e-34 117.7 0.0 2e-10 40.5 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10933.1 - 5.5e-15 55.3 0.0 4.5e-08 32.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ10933.1 - 0.0007 19.6 0.1 0.003 17.5 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family F-box PF00646.33 OAJ10933.1 - 0.028 14.3 2.4 0.079 12.9 2.4 1.8 1 0 0 1 1 1 0 F-box domain PDT PF00800.18 OAJ10934.1 - 1.9e-41 141.9 0.0 2.8e-35 121.8 0.0 3.4 2 2 0 2 2 2 2 Prephenate dehydratase Pkinase PF00069.25 OAJ10944.1 - 6.1e-43 147.1 0.0 7.8e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10944.1 - 1.2e-23 83.8 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-BED PF02892.15 OAJ10945.1 - 0.16 12.0 1.4 0.34 11.0 1.4 1.5 1 0 0 1 1 1 0 BED zinc finger Dimer_Tnp_hAT PF05699.14 OAJ10946.1 - 6.4e-13 48.3 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BUD22 PF09073.10 OAJ10946.1 - 0.12 11.7 16.0 0.21 10.9 16.0 1.3 1 0 0 1 1 1 0 BUD22 DUF4413 PF14372.6 OAJ10946.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) TFIID_20kDa PF03847.13 OAJ10953.1 - 9.5e-32 109.3 0.3 1.5e-31 108.7 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OAJ10953.1 - 0.0094 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ10953.1 - 0.018 15.1 0.0 0.076 13.1 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Occludin_ELL PF07303.13 OAJ10953.1 - 0.066 13.9 0.1 0.066 13.9 0.1 2.4 3 0 0 3 3 3 0 Occludin homology domain Histone PF00125.24 OAJ10953.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 DUF4413 PF14372.6 OAJ10961.1 - 0.00083 19.7 0.4 0.0033 17.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) CHRD PF07452.12 OAJ10971.1 - 1.5e-29 103.3 3.2 1e-13 52.3 0.3 2.2 2 0 0 2 2 2 2 CHRD domain Acetyltransf_3 PF13302.7 OAJ10972.1 - 5.1e-09 36.9 0.0 6.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tugs PF17840.1 OAJ10972.1 - 0.041 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Lactonase PF10282.9 OAJ10974.1 - 1.5e-17 63.9 0.0 6.9e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Chorion_S16 PF05836.12 OAJ10981.1 - 0.086 13.1 0.9 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Chorion protein S16 NDC10_II PF16787.5 OAJ10982.1 - 1.3e-60 205.1 0.0 1.8e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ10982.1 - 1.5e-17 63.6 0.5 3.1e-17 62.6 0.5 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MAP65_ASE1 PF03999.12 OAJ10982.1 - 0.072 11.8 0.1 0.14 10.8 0.1 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Mid1 PF12929.7 OAJ10983.1 - 3.6e-54 184.6 0.0 5.4e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAJ10983.1 - 0.01 16.4 2.2 0.04 14.5 0.2 2.3 2 0 0 2 2 2 0 Fz domain RT_RNaseH_2 PF17919.1 OAJ10991.1 - 9.1e-30 102.7 0.0 2.2e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10991.1 - 1.2e-27 96.2 0.0 3.6e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10991.1 - 8.2e-21 74.5 0.0 2.3e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10991.1 - 7.7e-14 51.9 0.0 2.3e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ10991.1 - 1.5e-08 34.6 0.4 3e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ10991.1 - 0.0052 16.5 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.14 OAJ10992.1 - 2.5e-23 81.7 0.2 7.1e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAJ10992.1 - 0.0087 15.9 0.0 0.028 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 OAJ10992.1 - 0.019 15.0 2.0 0.056 13.5 2.0 1.8 1 0 0 1 1 1 0 BED zinc finger Cofilin_ADF PF00241.20 OAJ11000.1 - 1.2e-19 70.3 0.0 1.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 OAJ11000.1 - 2e-13 50.0 0.2 2e-13 50.0 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAJ11000.1 - 9.8e-13 47.5 1.4 1.7e-12 46.8 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAJ11000.1 - 1.4e-08 34.2 0.2 1.7e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain DUF3915 PF13054.6 OAJ11001.1 - 0.14 12.1 0.3 0.14 12.1 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Mob1_phocein PF03637.17 OAJ11002.1 - 3.2e-21 76.1 0.0 4.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Vfa1 PF08432.10 OAJ11002.1 - 0.0065 16.8 0.3 0.01 16.2 0.3 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 W2 PF02020.18 OAJ11003.1 - 6.4e-14 51.8 2.2 6.4e-14 51.8 2.2 3.5 3 2 1 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAJ11003.1 - 1.4e-08 34.2 1.1 8.7e-05 22.1 0.2 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAJ11003.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 OAJ11003.1 - 0.0022 17.0 0.1 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 OAJ11003.1 - 0.0035 17.1 2.6 0.029 14.1 2.6 2.4 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 OAJ11003.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Glyco_tranf_2_4 PF13704.6 OAJ11003.1 - 0.041 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 BUD22 PF09073.10 OAJ11003.1 - 0.85 8.9 38.3 0.062 12.6 20.7 2.2 2 0 0 2 2 2 0 BUD22 Lin-8 PF03353.15 OAJ11003.1 - 5.6 6.4 6.3 14 5.2 6.3 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec15 PF04091.12 OAJ11012.1 - 5e-83 279.1 0.0 1.8e-82 277.3 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 OAJ11012.1 - 9.7e-06 25.5 0.1 9.7e-06 25.5 0.1 3.1 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain MnmE_helical PF12631.7 OAJ11012.1 - 0.0019 18.4 1.8 4.5 7.4 0.6 3.7 3 1 0 3 3 3 1 MnmE helical domain COG5 PF10392.9 OAJ11012.1 - 0.0026 17.9 3.4 0.015 15.4 0.1 3.3 3 1 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 OAJ11012.1 - 0.012 15.7 0.2 0.089 12.9 0.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 CENP-F_leu_zip PF10473.9 OAJ11012.1 - 0.045 13.8 1.5 0.78 9.8 0.0 3.5 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec5 PF15469.6 OAJ11012.1 - 0.055 13.3 0.1 0.23 11.2 0.1 2.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 COG2 PF06148.11 OAJ11012.1 - 0.26 11.4 3.3 0.54 10.3 0.6 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DDE_Tnp_4 PF13359.6 OAJ11014.1 - 3.6e-25 88.5 0.0 5.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ11014.1 - 8.7e-08 32.0 0.0 9.3e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ11014.1 - 5.7e-05 22.9 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAJ11014.1 - 0.00021 21.6 2.0 0.002 18.5 0.1 2.4 2 0 0 2 2 2 1 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 OAJ11015.1 - 3.1e-17 63.3 0.1 5e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ11015.1 - 5.9e-06 26.6 0.6 0.00012 22.4 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NAD_binding_10 PF13460.6 OAJ11023.1 - 3.1e-08 33.7 0.1 7.5e-07 29.2 0.1 2.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAJ11023.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase WD40 PF00400.32 OAJ11024.1 - 1.3e-08 35.4 3.7 0.0071 17.2 0.0 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF3106 PF11304.8 OAJ11032.1 - 0.033 14.7 0.6 0.033 14.7 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Dimer_Tnp_hAT PF05699.14 OAJ11033.1 - 9.7e-17 60.5 0.1 2.2e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 OAJ11033.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain RVT_1 PF00078.27 OAJ11034.1 - 0.021 14.4 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 OAJ11035.1 - 4.6e-49 167.1 0.0 6.4e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11035.1 - 1e-29 103.6 0.0 2e-29 102.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase GAS PF13851.6 OAJ11035.1 - 0.032 13.6 1.6 0.05 12.9 1.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Kdo PF06293.14 OAJ11035.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0242 PF06785.11 OAJ11035.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CK2S PF15011.6 OAJ11035.1 - 0.12 12.3 2.1 0.22 11.4 2.1 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate CLZ PF16526.5 OAJ11035.1 - 0.17 12.3 0.5 6.4 7.2 0.2 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Allexi_40kDa PF05549.11 OAJ11035.1 - 0.18 11.3 1.0 0.68 9.4 0.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein RTC4 PF14474.6 OAJ11035.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 RTC4-like domain DUF4407 PF14362.6 OAJ11035.1 - 0.22 10.9 1.3 0.32 10.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 OAJ11035.1 - 0.24 11.6 1.5 11 6.4 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ATG16 PF08614.11 OAJ11035.1 - 0.31 11.3 4.2 0.55 10.4 4.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4763 PF15960.5 OAJ11035.1 - 0.36 10.1 4.0 0.61 9.4 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF4140 PF13600.6 OAJ11035.1 - 1.7 9.1 10.1 3.8 8.0 0.7 3.7 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 OAJ11035.1 - 4.9 7.6 5.6 57 4.1 0.1 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain DivIC PF04977.15 OAJ11035.1 - 7.3 6.4 7.6 4.1 7.2 0.4 2.7 2 1 1 3 3 3 0 Septum formation initiator COesterase PF00135.28 OAJ11043.1 - 6.6e-42 144.0 2.9 1.6e-40 139.5 2.9 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ11043.1 - 2.4e-06 27.5 0.1 5.8e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ11043.1 - 0.0073 16.9 0.2 0.011 16.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ATP_bind_1 PF03029.17 OAJ11044.1 - 3.6e-74 249.6 0.0 4.4e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAJ11044.1 - 0.00012 22.0 0.0 0.00033 20.5 0.0 1.9 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 OAJ11044.1 - 0.0075 16.3 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 OAJ11044.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CBP_BcsQ PF06564.12 OAJ11044.1 - 0.014 14.9 0.0 22 4.4 0.0 3.2 2 1 0 3 3 3 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 OAJ11044.1 - 0.02 15.3 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 OAJ11044.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ11044.1 - 0.025 14.3 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ11044.1 - 0.049 13.8 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAJ11044.1 - 0.058 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OAJ11044.1 - 0.088 13.1 0.0 0.3 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAJ11044.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RibD_C PF01872.17 OAJ11055.1 - 6.8e-34 117.5 0.0 2e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 RibD C-terminal domain Sec7 PF01369.20 OAJ11055.1 - 2.1e-31 109.0 0.0 2.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain His_biosynth PF00977.21 OAJ11056.1 - 2.4e-36 125.3 0.1 3.1e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 OAJ11056.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Prp19 PF08606.11 OAJ11057.1 - 2.4e-29 101.1 1.6 5e-29 100.1 1.6 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 OAJ11057.1 - 9.6e-22 76.9 3.3 5.7e-05 23.8 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11057.1 - 4.3e-14 52.6 0.1 0.027 14.8 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 OAJ11057.1 - 0.00098 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OAJ11057.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 OAJ11057.1 - 0.021 14.2 0.1 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-NOSIP PF15906.5 OAJ11057.1 - 0.022 14.9 0.0 0.065 13.4 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF3450 PF11932.8 OAJ11057.1 - 0.52 9.6 4.1 0.094 12.0 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ADH_zinc_N_2 PF13602.6 OAJ11058.1 - 6.4e-18 66.1 0.0 1.3e-17 65.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ11058.1 - 1.8e-15 57.0 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.22 OAJ11058.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain ADH_N PF08240.12 OAJ11058.1 - 0.078 12.9 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ11058.1 - 0.15 12.0 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase SpoV PF08183.11 OAJ11058.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein family Phage_integrase PF00589.22 OAJ11064.1 - 0.00069 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF3979 PF13141.6 OAJ11065.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Stm1_N PF09598.10 OAJ11065.1 - 0.31 11.9 8.5 0.77 10.6 8.5 1.6 1 0 0 1 1 1 0 Stm1 PSRT PF07636.11 OAJ11065.1 - 0.46 10.2 6.2 1.2 8.9 6.2 1.7 1 0 0 1 1 1 0 PSRT Asp_protease_2 PF13650.6 OAJ11066.1 - 2.4e-06 28.1 0.0 5.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11066.1 - 4.2e-05 24.0 0.0 9.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease K_channel_TID PF07941.11 OAJ11071.1 - 0.12 12.8 7.7 1.6 9.2 7.7 2.3 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PRCH PF03967.13 OAJ11084.1 - 0.11 12.8 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF4813 PF16072.5 OAJ11085.1 - 0.38 10.4 16.6 0.52 9.9 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) NDC10_II PF16787.5 OAJ11086.1 - 7.2e-48 163.3 0.0 9.7e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_Tnp_1 PF01527.20 OAJ11086.1 - 0.043 14.1 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 OAJ11086.1 - 0.057 13.4 0.0 0.25 11.4 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn helix G-patch PF01585.23 OAJ11091.1 - 7.4e-10 38.6 8.1 1.1e-09 38.0 3.3 2.4 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ11091.1 - 0.00017 21.6 1.9 0.00031 20.7 1.8 1.6 1 1 1 2 2 2 1 G-patch domain STIMATE PF12400.8 OAJ11093.1 - 2.3e-39 134.8 6.1 3.3e-39 134.3 6.1 1.2 1 0 0 1 1 1 1 STIMATE family DAP3 PF10236.9 OAJ11094.1 - 2e-37 129.1 0.0 7.5e-37 127.2 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OAJ11094.1 - 2.7e-05 24.6 0.7 5.9e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ11094.1 - 0.0069 16.7 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain GTP1_OBG PF01018.22 OAJ11095.1 - 2.2e-41 141.0 0.9 3.2e-29 101.5 1.8 3.3 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 OAJ11095.1 - 2.7e-18 66.1 0.0 6.2e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ11095.1 - 0.00036 20.1 0.2 0.0007 19.1 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B UBN_AB PF14075.6 OAJ11095.1 - 0.22 11.2 0.1 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Fe-ADH_2 PF13685.6 OAJ11095.1 - 0.22 11.2 1.0 1.3 8.6 0.2 2.3 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase ABC_tran PF00005.27 OAJ11095.1 - 0.51 10.9 0.1 0.51 10.9 0.1 2.3 3 0 0 3 3 3 0 ABC transporter CDC27 PF09507.10 OAJ11100.1 - 7.8 5.8 23.7 0.63 9.4 17.6 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DDE_3 PF13358.6 OAJ11101.1 - 3.4e-14 52.8 0.0 5.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ11101.1 - 5e-06 27.0 0.1 5e-06 27.0 0.1 2.5 2 1 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ11101.1 - 8.3e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 OAJ11101.1 - 0.00038 20.6 0.2 0.001 19.2 0.2 1.8 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.19 OAJ11101.1 - 0.044 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease Tankyrase_bdg_C PF15327.6 OAJ11101.1 - 0.07 13.6 0.1 0.16 12.4 0.0 1.6 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain WASH-7_C PF14746.6 OAJ11101.1 - 0.17 11.6 0.0 8 6.1 0.0 2.2 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DDHD PF02862.17 OAJ11108.1 - 6.7e-22 78.7 14.8 8.4e-22 78.4 0.0 3.3 2 1 0 2 2 2 1 DDHD domain PAS_9 PF13426.7 OAJ11110.1 - 3.9e-18 65.6 0.0 2e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAJ11110.1 - 4.1e-07 30.0 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAJ11110.1 - 2.3e-06 27.8 0.0 0.00015 22.0 0.0 2.8 2 0 0 2 2 2 1 PAS fold RGS PF00615.19 OAJ11110.1 - 1.7e-05 25.1 0.1 5.4e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS_3 PF08447.12 OAJ11110.1 - 7.6e-05 22.9 0.0 0.0049 17.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OAJ11110.1 - 0.13 12.3 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 PAS domain Cwf_Cwc_15 PF04889.12 OAJ11110.1 - 0.22 11.2 6.8 3.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_21 PF13506.6 OAJ11117.1 - 3.3e-24 85.3 0.1 7e-10 38.7 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAJ11117.1 - 1.4e-13 51.3 0.0 5.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAJ11117.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 PrgI PF12666.7 OAJ11117.1 - 0.44 11.3 1.9 0.59 10.9 0.4 1.9 2 0 0 2 2 2 0 PrgI family protein SPC22 PF04573.12 OAJ11118.1 - 5.5e-53 179.0 0.3 6.2e-53 178.8 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit APG6 PF04111.12 OAJ11119.1 - 5.4e-65 218.7 0.0 9.9e-65 217.8 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAJ11119.1 - 1.5e-24 87.0 19.5 1.5e-24 87.0 19.5 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region SOGA PF11365.8 OAJ11119.1 - 0.24 12.6 12.2 0.98 10.6 8.3 3.3 2 1 1 3 3 3 0 Protein SOGA YabA PF06156.13 OAJ11119.1 - 0.44 11.2 3.8 0.69 10.6 2.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 OAJ11119.1 - 0.96 8.0 3.0 1.4 7.4 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 OAJ11119.1 - 5.8 7.2 7.5 2.1 8.6 4.4 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein IMS PF00817.20 OAJ11120.1 - 5.9e-45 152.9 0.2 1e-44 152.1 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ11120.1 - 2.3e-12 47.6 0.6 6.2e-12 46.3 0.6 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ11120.1 - 0.0014 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PRA1 PF03208.19 OAJ11121.1 - 1.1e-33 115.9 0.1 1.3e-33 115.6 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein YrhK PF14145.6 OAJ11121.1 - 2.4 8.1 8.0 1.9 8.4 1.9 2.3 2 0 0 2 2 2 0 YrhK-like protein NDC10_II PF16787.5 OAJ11129.1 - 1.7e-41 142.3 0.0 2.2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ11129.1 - 5.4e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1 PF01527.20 OAJ11129.1 - 0.052 13.9 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 Transposase HTH_Tnp_1_2 PF13022.6 OAJ11129.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase NDC10_II PF16787.5 OAJ11131.1 - 1.1e-38 133.1 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 THOC2_N PF16134.5 OAJ11139.1 - 6.4e-114 381.9 2.7 9.8e-114 381.3 0.0 2.1 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAJ11139.1 - 1.9e-68 230.9 12.1 6e-67 226.0 0.6 3.4 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAJ11139.1 - 6.8e-24 83.7 0.1 1.6e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RRM_1 PF00076.22 OAJ11140.1 - 4e-32 109.8 0.9 8.9e-20 70.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAJ11140.1 - 0.0011 18.9 0.0 0.51 10.4 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_Rrp7 PF17799.1 OAJ11140.1 - 0.0031 17.4 0.0 1.5 8.6 0.0 2.7 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 OAJ11140.1 - 0.014 15.5 0.1 1.8 8.8 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 OAJ11140.1 - 0.015 15.6 0.1 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAJ11140.1 - 0.021 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gpr1_Fun34_YaaH PF01184.19 OAJ11149.1 - 4.7e-45 153.7 8.2 5.8e-45 153.5 8.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2417 PF10329.9 OAJ11149.1 - 0.015 14.7 3.4 1.2 8.5 0.0 2.2 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Aminotran_5 PF00266.19 OAJ11150.1 - 3.2e-87 292.9 0.0 4.8e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ11150.1 - 0.00021 20.6 0.2 0.00036 19.9 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAJ11150.1 - 0.08 11.5 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DASH_Hsk3 PF08227.11 OAJ11151.1 - 2.9e-07 30.7 3.0 4.2e-07 30.2 3.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like SHQ1 PF04925.15 OAJ11152.1 - 2.2e-22 79.5 0.0 1.5e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 SHQ1 protein YuzL PF14115.6 OAJ11152.1 - 1.1 9.8 4.1 3.8 8.1 4.1 2.0 1 0 0 1 1 1 0 YuzL-like protein PPP4R2 PF09184.11 OAJ11152.1 - 1.7 8.2 3.9 2.5 7.6 3.9 1.1 1 0 0 1 1 1 0 PPP4R2 Cys_Met_Meta_PP PF01053.20 OAJ11153.1 - 1.9e-95 319.7 0.0 2.1e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAJ11153.1 - 2e-10 40.4 0.1 2.5e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ11153.1 - 1.2e-09 37.6 0.3 1.6e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAJ11153.1 - 1.5e-09 37.7 0.2 2.4e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 OAJ11153.1 - 3.3e-05 22.6 0.0 4.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 OAJ11153.1 - 0.00072 18.9 0.1 0.002 17.5 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OAJ11153.1 - 0.22 10.1 0.1 0.29 9.8 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Apolipoprotein PF01442.18 OAJ11163.1 - 0.014 15.3 2.8 0.095 12.6 0.7 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Retrotran_gag_2 PF14223.6 OAJ11165.1 - 2e-15 56.7 0.1 3.4e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ11165.1 - 0.0081 16.2 8.6 0.15 12.2 1.2 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 OAJ11165.1 - 0.15 11.8 2.8 15 5.4 1.1 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger DUF4218 PF13960.6 OAJ11175.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) BAAT_C PF08840.11 OAJ11176.1 - 0.048 13.6 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 OAJ11176.1 - 0.063 13.9 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DHR10 PF18595.1 OAJ11178.1 - 0.0017 18.4 6.0 0.0017 18.4 6.0 3.3 3 0 0 3 3 3 1 Designed helical repeat protein 10 domain CLZ PF16526.5 OAJ11178.1 - 0.011 16.0 4.1 0.011 16.0 4.1 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoL PF05461.11 OAJ11178.1 - 0.033 13.5 3.2 0.04 13.3 0.1 2.3 2 0 0 2 2 2 0 Apolipoprotein L FlaC_arch PF05377.11 OAJ11178.1 - 0.19 12.1 1.6 2.5 8.6 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 OAJ11178.1 - 0.2 9.5 4.4 0.11 10.4 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DASH_Spc19 PF08287.11 OAJ11178.1 - 1.4 8.8 16.5 1.3 8.9 2.2 2.7 2 0 0 2 2 2 0 Spc19 Mto2_bdg PF12808.7 OAJ11178.1 - 1.4 9.3 13.7 0.039 14.3 4.8 2.8 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CDC45 PF02724.14 OAJ11178.1 - 2.9 6.1 11.2 0.029 12.7 2.1 1.9 2 0 0 2 2 2 0 CDC45-like protein Exonuc_VII_L PF02601.15 OAJ11178.1 - 3.7 7.0 13.2 0.67 9.5 4.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit YabA PF06156.13 OAJ11178.1 - 4.9 7.8 10.3 0.19 12.4 0.6 2.9 3 0 0 3 3 3 0 Initiation control protein YabA GAS PF13851.6 OAJ11178.1 - 5 6.4 15.1 0.05 13.0 2.1 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OAJ11178.1 - 7.4 5.4 14.3 0.38 9.6 5.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 OAJ11178.1 - 7.7 7.1 6.3 1.4 9.4 0.8 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cytochrom_NNT PF03264.14 OAJ11179.1 - 0.088 12.5 3.4 0.14 11.8 3.4 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region zf-CCHC PF00098.23 OAJ11179.1 - 0.089 12.9 5.4 0.17 12.1 5.4 1.5 1 0 0 1 1 1 0 Zinc knuckle SDA1 PF05285.12 OAJ11179.1 - 9.9 5.5 13.2 22 4.3 13.3 1.6 1 1 0 1 1 1 0 SDA1 Aldo_ket_red PF00248.21 OAJ11190.1 - 1.5e-27 96.6 0.0 7.2e-27 94.3 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Sybindin PF04099.12 OAJ11191.1 - 2.7e-07 30.6 0.8 5.1e-07 29.7 0.8 1.4 1 1 0 1 1 1 1 Sybindin-like family SMK-1 PF04802.15 OAJ11192.1 - 1e-77 260.3 2.1 2.3e-77 259.2 2.1 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 RVT_2 PF07727.14 OAJ11198.1 - 3.9e-13 49.6 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ11198.1 - 0.0033 17.2 3.5 0.0065 16.3 3.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like Brr6_like_C_C PF10104.9 OAJ11199.1 - 9.9e-08 31.8 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain rve PF00665.26 OAJ11200.1 - 1.1e-17 64.4 0.0 2.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ11200.1 - 4.7e-15 55.5 0.0 8.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ11200.1 - 0.001 18.6 1.3 0.0013 18.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 OAJ11200.1 - 0.0028 17.4 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ11200.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain HTH_15 PF12324.8 OAJ11200.1 - 0.11 12.5 0.1 2.7 8.0 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase zf-CCHC PF00098.23 OAJ11200.1 - 1 9.5 3.4 2.3 8.4 3.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Keratin_2_head PF16208.5 OAJ11200.1 - 1.5 9.0 15.2 3.8 7.6 15.2 1.6 1 0 0 1 1 1 0 Keratin type II head Pkinase PF00069.25 OAJ11207.1 - 6.8e-40 137.1 0.0 5.1e-27 94.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11207.1 - 2.5e-16 59.7 0.0 5.7e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ11207.1 - 0.15 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase BUD22 PF09073.10 OAJ11207.1 - 9.1 5.5 21.3 22 4.2 21.3 1.6 1 0 0 1 1 1 0 BUD22 Steroid_dh PF02544.16 OAJ11208.1 - 7e-23 81.3 1.9 1.1e-07 31.9 0.0 4.2 3 1 1 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAJ11208.1 - 0.008 15.7 0.1 0.02 14.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Exo_endo_phos PF03372.23 OAJ11209.1 - 1.1e-19 70.9 0.0 1.1e-19 70.9 0.0 3.2 3 2 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 OAJ11209.1 - 7.8e-10 38.9 3.1 0.00044 20.6 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ11209.1 - 1.6e-08 34.2 5.5 2.1e-05 24.2 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat CENP-B_dimeris PF09026.10 OAJ11209.1 - 3.8 8.0 7.7 0.18 12.2 1.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop53 PF07767.11 OAJ11209.1 - 5 6.4 13.3 11 5.3 13.3 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pam16 PF03656.13 OAJ11210.1 - 3e-11 43.4 10.4 5.1e-07 29.7 10.4 3.9 1 1 0 1 1 1 1 Pam16 Dehydrin PF00257.19 OAJ11210.1 - 0.74 10.4 5.0 7.4 7.1 0.3 2.1 2 0 0 2 2 2 0 Dehydrin WPP PF13943.6 OAJ11210.1 - 9.6 6.7 8.6 3.1 8.3 0.7 2.7 2 1 1 3 3 3 0 WPP domain GRASP55_65 PF04495.14 OAJ11215.1 - 7.8e-56 188.2 0.0 2.6e-48 163.9 0.0 2.4 2 1 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OAJ11215.1 - 0.0014 18.4 0.2 0.5 10.3 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OAJ11215.1 - 0.016 15.5 0.0 11 6.4 0.0 3.3 3 1 0 3 3 3 0 PDZ domain Myc_N PF01056.18 OAJ11215.1 - 0.085 12.7 1.4 0.13 12.1 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 OAJ11215.1 - 1.6 9.4 12.8 0.13 12.8 5.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.12 OAJ11216.1 - 4e-26 91.6 20.2 4e-26 91.6 20.2 19.3 7 4 11 18 18 18 7 TPR/MLP1/MLP2-like protein RVT_1 PF00078.27 OAJ11223.1 - 3.5e-20 72.5 0.1 7.2e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ11223.1 - 1.4e-16 60.7 0.0 4.1e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ11223.1 - 5.6e-13 48.8 0.0 1.6e-06 28.1 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11223.1 - 7.2e-13 48.7 0.0 1.7e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11223.1 - 2e-12 47.0 0.0 4.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 OAJ11223.1 - 0.022 15.4 0.0 0.068 13.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 OAJ11223.1 - 0.045 13.5 0.0 0.15 11.8 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain DUF4336 PF14234.6 OAJ11223.1 - 0.1 11.8 0.4 0.74 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) zf-CCHC_2 PF13696.6 OAJ11223.1 - 0.32 10.9 1.6 0.66 9.8 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 OAJ11223.1 - 0.44 10.7 10.5 0.022 14.8 3.5 2.3 2 0 0 2 2 2 0 Zinc knuckle PLA2_B PF01735.18 OAJ11230.1 - 9.5e-14 50.7 0.0 1.2e-06 27.2 0.0 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain Pkinase PF00069.25 OAJ11231.1 - 3.7e-72 242.9 0.0 5e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11231.1 - 6.2e-36 124.0 0.0 9.2e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OAJ11231.1 - 4.8e-19 69.0 0.1 3.6e-17 62.9 0.0 2.7 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 OAJ11231.1 - 3.3e-07 29.9 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 OAJ11231.1 - 8.6e-05 22.6 1.2 0.00012 22.1 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) AAA_lid_3 PF17862.1 OAJ11231.1 - 0.015 15.0 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA+ lid domain RIO1 PF01163.22 OAJ11231.1 - 0.03 13.9 0.1 0.065 12.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OAJ11231.1 - 0.17 10.8 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MULE PF10551.9 OAJ11238.1 - 4.7e-08 33.3 0.1 0.0016 18.8 0.0 2.4 1 1 1 2 2 2 2 MULE transposase domain SWIM PF04434.17 OAJ11238.1 - 0.0013 18.4 0.1 0.0027 17.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Apt1 PF10351.9 OAJ11247.1 - 0.01 14.8 1.5 0.0087 15.0 1.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAJ11247.1 - 0.011 14.4 2.6 0.0096 14.5 2.6 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OAJ11247.1 - 0.089 12.4 23.9 0.13 11.9 23.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 OAJ11247.1 - 0.43 10.3 8.4 0.57 9.9 8.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1635 PF07795.11 OAJ11247.1 - 2.1 8.2 7.4 2.7 7.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4614 PF15391.6 OAJ11247.1 - 2.7 7.9 14.8 3.5 7.6 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CCDC106 PF15794.5 OAJ11247.1 - 4.5 6.9 11.0 5.9 6.5 11.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF1754 PF08555.10 OAJ11247.1 - 5.5 7.8 9.3 7.2 7.5 7.2 1.9 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CCDC24 PF15669.5 OAJ11247.1 - 6.9 6.5 7.9 8.8 6.1 7.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family zf-C2H2 PF00096.26 OAJ11248.1 - 0.00075 19.8 1.1 0.0012 19.1 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ11248.1 - 0.057 14.3 0.1 0.15 13.0 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Zip PF02535.22 OAJ11249.1 - 0.0077 15.5 0.2 0.01 15.1 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Presenilin PF01080.17 OAJ11249.1 - 0.082 11.7 0.3 0.088 11.6 0.3 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OAJ11249.1 - 0.12 11.2 2.2 0.13 11.1 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 OAJ11249.1 - 0.23 11.7 13.2 0.38 11.0 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SWIRM-assoc_2 PF16496.5 OAJ11249.1 - 0.43 9.4 6.3 0.54 9.1 6.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Med19 PF10278.9 OAJ11249.1 - 1.1 9.2 9.0 1.4 8.8 9.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 OAJ11249.1 - 1.1 9.0 4.4 1.4 8.7 4.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 OAJ11249.1 - 1.2 9.0 10.0 1.5 8.7 10.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 OAJ11249.1 - 2.8 6.1 8.7 3.2 5.9 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 OAJ11249.1 - 3 6.6 5.7 3.4 6.4 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CCDC106 PF15794.5 OAJ11249.1 - 5.1 6.7 8.8 6.3 6.4 8.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MULE PF10551.9 OAJ11258.1 - 4.8e-21 75.0 0.1 1.1e-20 73.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ11258.1 - 1.8e-07 31.7 2.6 3e-06 27.9 0.6 2.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 OAJ11258.1 - 0.0049 17.3 0.1 0.0049 17.3 0.1 1.9 2 0 0 2 2 2 1 Transcription factor AFT SURF4 PF02077.15 OAJ11260.1 - 5.4e-95 318.0 3.2 6.2e-95 317.8 3.2 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 OAJ11260.1 - 0.0076 16.2 0.9 0.014 15.4 0.2 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5562) Citrate_bind PF16114.5 OAJ11261.1 - 2.8e-89 297.3 0.1 5.9e-89 296.3 0.1 1.6 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 OAJ11261.1 - 2.9e-20 72.6 0.1 1.7e-17 63.6 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 OAJ11261.1 - 2.2e-14 53.5 0.1 6e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 OAJ11261.1 - 7.8e-12 45.7 0.0 2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 OAJ11261.1 - 1.2e-06 28.3 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 OAJ11261.1 - 5.9e-05 22.9 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 OAJ11261.1 - 0.031 13.7 0.0 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain RVT_1 PF00078.27 OAJ11268.1 - 4.4e-11 42.7 0.0 1.1e-08 34.9 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ11268.1 - 0.00011 22.8 0.0 0.00028 21.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OAJ11268.1 - 0.0034 17.7 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ11268.1 - 0.0051 17.3 0.0 0.014 16.0 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-C2H2_11 PF16622.5 OAJ11269.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type Serglycin PF04360.12 OAJ11269.1 - 0.0096 15.9 2.8 0.018 15.0 2.8 1.4 1 0 0 1 1 1 1 Serglycin zf-C2H2 PF00096.26 OAJ11269.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ11269.1 - 0.13 13.1 7.3 3.7 8.6 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger tRNA-synt_2b PF00587.25 OAJ11270.1 - 2.8e-35 121.9 0.0 4.5e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAJ11270.1 - 1.5e-17 63.8 3.2 1.5e-17 63.8 3.2 1.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 OAJ11270.1 - 0.052 13.5 2.0 0.11 12.5 2.0 1.5 1 0 0 1 1 1 0 FlxA-like protein DcpS_C PF11969.8 OAJ11271.1 - 0.0048 17.4 0.1 0.0065 16.9 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ11271.1 - 0.028 15.2 0.1 0.074 13.8 0.0 1.6 2 0 0 2 2 2 0 HIT domain COesterase PF00135.28 OAJ11272.1 - 2.7e-56 191.5 0.0 6.9e-56 190.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ11272.1 - 5.9e-11 42.6 0.2 7.4e-10 39.0 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 OAJ11272.1 - 0.0012 18.4 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 OAJ11272.1 - 0.063 12.9 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 OAJ11272.1 - 0.18 11.3 0.1 0.31 10.5 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Nuc_sug_transp PF04142.15 OAJ11281.1 - 4e-06 26.2 0.3 6.1e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 OAJ11281.1 - 1.6e-05 24.4 4.9 9.9e-05 21.8 0.7 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 OAJ11281.1 - 0.00049 20.3 4.1 0.00049 20.3 4.1 3.0 3 1 0 3 3 3 2 EamA-like transporter family MFS_2 PF13347.6 OAJ11282.1 - 1.1e-10 40.7 1.0 1.1e-10 40.7 1.0 3.9 2 1 2 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAJ11282.1 - 0.0015 17.5 0.1 0.0034 16.3 0.1 1.6 1 0 0 1 1 1 1 MFS_1 like family DUF1980 PF09323.10 OAJ11282.1 - 0.0062 16.5 0.0 0.078 12.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) MFS_1 PF07690.16 OAJ11282.1 - 0.0072 15.3 40.8 0.0024 16.8 35.4 2.7 2 2 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 OAJ11282.1 - 0.038 12.2 0.4 0.082 11.1 0.4 1.5 1 0 0 1 1 1 0 BT1 family LSM PF01423.22 OAJ11283.1 - 2.3e-22 78.5 0.1 2.6e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ11283.1 - 0.001 19.2 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain PWI PF01480.17 OAJ11284.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 OAJ11284.1 - 4.6e-07 29.6 2.3 8e-07 28.8 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAJ11284.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 OAJ11284.1 - 0.00042 20.3 6.4 0.00076 19.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 OAJ11284.1 - 0.012 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OAJ11284.1 - 0.034 14.8 0.2 0.034 14.8 0.2 2.2 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 OAJ11284.1 - 0.11 12.3 3.1 0.19 11.6 3.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger SUIM_assoc PF16619.5 OAJ11284.1 - 2.1 8.4 11.6 8.1 6.6 11.6 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LrgB PF04172.16 OAJ11285.1 - 2.2e-30 105.8 5.2 2.5e-30 105.6 5.2 1.0 1 0 0 1 1 1 1 LrgB-like family Gate PF07670.14 OAJ11285.1 - 0.082 13.2 4.8 0.15 12.3 4.8 1.7 1 1 0 1 1 1 0 Nucleoside recognition DUF2304 PF10066.9 OAJ11285.1 - 0.11 12.8 0.3 0.11 12.8 0.3 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) FAM70 PF14967.6 OAJ11285.1 - 0.41 10.1 4.6 0.56 9.6 4.6 1.2 1 0 0 1 1 1 0 FAM70 protein Forkhead PF00250.18 OAJ11294.1 - 2.2e-12 47.1 0.0 5.6e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain TFIIA PF03153.13 OAJ11294.1 - 0.013 15.5 27.3 0.11 12.4 4.5 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF533 PF04391.12 OAJ11294.1 - 4.1 6.9 19.8 0.22 11.1 4.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Cellulase PF00150.18 OAJ11296.1 - 0.0036 16.8 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DNA_pol_viral_C PF00336.18 OAJ11305.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.27 OAJ11305.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ASFV_J13L PF05568.11 OAJ11306.1 - 0.034 13.9 2.7 0.072 12.8 2.7 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein Phage_integrase PF00589.22 OAJ11306.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family 2OG-FeII_Oxy_3 PF13640.6 OAJ11309.1 - 4.7e-06 27.4 0.0 8.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps5 PF09325.10 OAJ11310.1 - 1.3e-59 201.6 4.7 1.3e-59 201.6 4.7 3.9 3 1 1 4 4 4 1 Vps5 C terminal like RmlD_sub_bind PF04321.17 OAJ11310.1 - 5.5e-49 166.8 0.0 5.5e-49 166.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 OAJ11310.1 - 1.6e-21 76.9 0.0 3.2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.24 OAJ11310.1 - 2e-21 76.1 0.0 6.9e-21 74.3 0.0 2.0 1 0 0 1 1 1 1 PX domain GDP_Man_Dehyd PF16363.5 OAJ11310.1 - 3.3e-08 33.3 0.0 3.3e-08 33.3 0.0 3.3 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAJ11310.1 - 7.8e-06 25.2 0.2 0.00015 21.0 0.0 2.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAJ11310.1 - 0.00025 20.3 0.0 0.00025 20.3 0.0 3.4 3 0 0 3 3 3 1 Male sterility protein BTB PF00651.31 OAJ11311.1 - 3e-12 46.7 0.1 1.6e-05 25.1 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain MATH PF00917.26 OAJ11311.1 - 0.13 12.4 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 MATH domain zf-U1 PF06220.12 OAJ11312.1 - 8e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 U1 zinc finger HsbA PF12296.8 OAJ11321.1 - 2.8e-17 63.3 14.2 5e-17 62.5 14.2 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Peptidase_S41_N PF11918.8 OAJ11321.1 - 0.027 14.7 2.2 0.084 13.1 1.5 2.0 1 1 1 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF1307 PF06998.11 OAJ11321.1 - 0.039 14.0 0.7 0.081 12.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) Cupin_8 PF13621.6 OAJ11322.1 - 3.5e-24 85.9 0.0 9.1e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAJ11322.1 - 1.5e-07 31.2 0.1 9.2e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 OAJ11322.1 - 7.2e-05 23.2 0.0 0.0031 17.9 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OAJ11322.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain HsbA PF12296.8 OAJ11323.1 - 2.5e-18 66.6 10.4 2.5e-18 66.6 10.4 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A GCN5L1 PF06320.13 OAJ11323.1 - 0.096 12.8 1.3 0.23 11.6 0.3 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF1307 PF06998.11 OAJ11323.1 - 0.14 12.1 2.7 6.7 6.7 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1307) Baculo_PEP_C PF04513.12 OAJ11323.1 - 1.4 8.9 9.6 2.4 8.2 9.2 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 OAJ11324.1 - 9e-19 68.1 15.2 9e-19 68.1 15.2 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A PIN_12 PF16289.5 OAJ11324.1 - 0.036 14.5 0.1 0.053 14.0 0.1 1.4 1 1 0 1 1 1 0 PIN domain Syntaxin-6_N PF09177.11 OAJ11324.1 - 0.16 12.6 0.7 0.26 11.8 0.3 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Phage_int_SAM_1 PF02899.17 OAJ11335.1 - 0.12 12.7 0.0 0.51 10.7 0.0 2.1 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CFEM PF05730.11 OAJ11343.1 - 0.0033 17.5 10.3 0.02 15.0 4.0 2.3 2 0 0 2 2 2 2 CFEM domain CFEM PF05730.11 OAJ11344.1 - 8e-08 32.3 9.9 1.2e-07 31.7 9.9 1.2 1 0 0 1 1 1 1 CFEM domain PglL_A PF15864.5 OAJ11344.1 - 0.021 14.5 0.1 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein glycosylation ligase TIL PF01826.17 OAJ11344.1 - 1.8 8.9 7.8 3 8.2 7.8 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain RRM_1 PF00076.22 OAJ11345.1 - 2.3e-12 46.5 0.0 3.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ11345.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif YqeY PF09424.10 OAJ11346.1 - 7.5e-24 84.4 1.0 9.5e-24 84.1 1.0 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF2880 PF11082.8 OAJ11346.1 - 0.01 16.1 0.9 0.03 14.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) DUF3365 PF11845.8 OAJ11346.1 - 0.019 15.3 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) WD40 PF00400.32 OAJ11347.1 - 5.4e-09 36.5 13.9 0.01 16.7 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11347.1 - 0.0016 18.7 0.0 1.2 9.5 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_D PF01813.17 OAJ11348.1 - 1.2e-72 243.9 2.4 1.8e-72 243.3 2.4 1.3 1 0 0 1 1 1 1 ATP synthase subunit D XRN_M PF17846.1 OAJ11348.1 - 0.59 9.0 2.5 0.92 8.4 2.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain NOA36 PF06524.12 OAJ11348.1 - 0.72 9.1 6.9 1.2 8.3 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 OAJ11348.1 - 3.3 7.6 14.5 4.7 7.1 14.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.6 OAJ11348.1 - 9.8 6.1 11.3 2.1 8.2 8.1 1.5 2 0 0 2 2 2 0 Spore coat protein CotO CFEM PF05730.11 OAJ11349.1 - 8.4e-07 29.0 12.1 1.7e-06 28.0 12.1 1.6 1 1 0 1 1 1 1 CFEM domain Toxin_3 PF00537.18 OAJ11349.1 - 0.073 13.3 6.6 0.16 12.2 6.6 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain EXOSC1 PF10447.9 OAJ11354.1 - 1.7e-25 89.7 0.1 3.9e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 CENP-H PF05837.12 OAJ11355.1 - 0.0029 18.0 14.0 0.01 16.3 9.7 2.9 2 0 0 2 2 2 1 Centromere protein H (CENP-H) KASH_CCD PF14662.6 OAJ11355.1 - 0.2 11.5 16.9 0.53 10.1 8.8 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OAJ11355.1 - 0.2 11.7 15.6 0.25 11.4 3.3 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OAJ11355.1 - 0.23 10.8 13.5 2.4 7.5 7.5 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Phlebovirus_NSM PF07246.11 OAJ11355.1 - 0.57 9.5 6.8 1.5 8.1 4.1 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF948 PF06103.11 OAJ11355.1 - 0.88 9.9 2.8 6.5 7.1 0.1 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) JIP_LZII PF16471.5 OAJ11355.1 - 1.3 9.2 12.9 0.15 12.2 0.5 3.8 3 1 2 5 5 5 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 OAJ11355.1 - 1.8 8.8 16.3 1.5 9.1 0.1 3.5 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 OAJ11355.1 - 5.4 7.3 11.4 4.4 7.6 0.2 4.9 6 0 0 6 6 6 0 Homeobox associated leucine zipper Fungal_TACC PF12709.7 OAJ11355.1 - 5.8 7.4 5.9 12 6.5 0.2 3.6 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 OAJ11355.1 - 7.3 5.4 19.7 19 4.0 4.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TFIIS_M PF07500.14 OAJ11356.1 - 9.3e-22 77.6 0.1 1.5e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAJ11356.1 - 3e-10 39.8 7.0 4.6e-10 39.2 7.0 1.3 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 OAJ11356.1 - 1.4e-06 28.3 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD_4 PF16866.5 OAJ11356.1 - 0.09 12.9 2.4 0.18 11.9 2.4 1.4 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 OAJ11356.1 - 0.47 10.1 1.6 0.78 9.4 1.6 1.4 1 0 0 1 1 1 0 PHD-finger Hid1 PF12722.7 OAJ11356.1 - 4.2 5.4 4.8 6.6 4.7 4.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_2 PF13639.6 OAJ11356.1 - 6.4 7.2 5.9 12 6.3 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain Peptidase_C97 PF05903.14 OAJ11357.1 - 5.7e-17 61.9 0.0 2.5e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain DUF4796 PF16044.5 OAJ11357.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Yippee-Mis18 PF03226.14 OAJ11364.1 - 1.2e-14 54.4 0.4 1.3e-14 54.2 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAJ11364.1 - 0.017 15.4 0.6 0.024 14.8 0.6 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I HNH_5 PF14279.6 OAJ11364.1 - 0.029 14.2 0.1 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Extensin-like_C PF06904.12 OAJ11364.1 - 0.032 14.3 0.3 0.044 13.8 0.3 1.1 1 0 0 1 1 1 0 Extensin-like protein C-terminus Zn_ribbon_SprT PF17283.2 OAJ11364.1 - 0.11 12.4 3.3 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Endonuclease_7 PF02945.15 OAJ11364.1 - 0.2 11.6 2.4 0.62 10.0 2.4 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII UPF0047 PF01894.17 OAJ11365.1 - 2.6e-38 130.7 0.0 3.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF3915 PF13054.6 OAJ11366.1 - 0.14 12.2 2.4 0.32 11.0 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) H_lectin PF09458.10 OAJ11376.1 - 7.6e-16 58.1 0.0 3.5e-07 30.3 0.0 3.4 3 1 0 3 3 3 2 H-type lectin domain GCR1_C PF12550.8 OAJ11378.1 - 2e-11 44.0 2.2 1.1e-10 41.7 0.1 2.2 1 1 1 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF1631 PF07793.11 OAJ11383.1 - 2.9 6.2 6.2 6.6 5.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RVT_1 PF00078.27 OAJ11384.1 - 3e-26 92.3 0.0 5.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ11384.1 - 2.4e-14 53.2 0.1 4.1e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11384.1 - 5.8e-10 39.4 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ11384.1 - 3.7e-09 36.5 0.0 7.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ11384.1 - 0.00028 21.5 0.0 0.0019 18.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ11384.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ11384.1 - 0.13 12.8 0.1 1.1 9.9 0.0 2.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ11384.1 - 0.15 12.3 0.3 0.39 11.0 0.1 1.8 2 0 0 2 2 2 0 H2C2 zinc finger HSF_DNA-bind PF00447.17 OAJ11397.1 - 1.7e-30 105.4 0.6 2.6e-30 104.9 0.6 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TRPM_tetra PF16519.5 OAJ11397.1 - 0.15 12.1 1.2 0.31 11.2 1.2 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM SRF-TF PF00319.18 OAJ11398.1 - 2.4e-21 74.9 0.0 4.2e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) UPF0172 PF03665.13 OAJ11399.1 - 1.9e-43 148.7 0.0 2.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) FAD_binding_1 PF00667.20 OAJ11406.1 - 1.4e-56 191.6 0.0 2.2e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAJ11406.1 - 4.6e-32 111.2 0.1 8.6e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAJ11406.1 - 1.3e-20 74.1 0.0 6.4e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain W2 PF02020.18 OAJ11407.1 - 2.5e-18 66.0 0.2 2.5e-18 66.0 0.2 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon zf-Nse PF11789.8 OAJ11409.1 - 2.2e-13 49.8 0.1 4.1e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3246 PF11596.8 OAJ11409.1 - 0.00051 19.5 5.6 0.001 18.6 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) U-box PF04564.15 OAJ11409.1 - 0.0068 16.6 0.0 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain SIL1 PF16782.5 OAJ11409.1 - 0.043 13.0 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 DUF5065 PF16723.5 OAJ11409.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) NOA36 PF06524.12 OAJ11409.1 - 1.6 7.9 0.0 1.6 7.9 0.0 2.7 2 2 0 2 2 2 0 NOA36 protein DnaJ PF00226.31 OAJ11418.1 - 5e-12 45.8 0.0 4.6e-08 33.1 0.0 2.8 3 0 0 3 3 3 2 DnaJ domain zf-CSL PF05207.13 OAJ11418.1 - 8.2e-09 35.1 4.6 2e-08 33.8 1.7 2.8 2 1 0 2 2 2 1 CSL zinc finger E7 PF00527.18 OAJ11418.1 - 0.16 12.2 1.7 0.33 11.2 0.2 2.2 2 1 0 2 2 2 0 E7 protein, Early protein JAB PF01398.21 OAJ11419.1 - 1.8e-13 50.5 0.0 3.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OAJ11419.1 - 1.5e-05 24.8 0.4 3.4e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UIM PF02809.20 OAJ11419.1 - 0.66 10.0 4.7 1.5 8.9 4.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Hid1 PF12722.7 OAJ11419.1 - 1.6 6.8 6.8 2.3 6.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein APH PF01636.23 OAJ11420.1 - 2.2e-08 34.3 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_4 PF12799.7 OAJ11421.1 - 8.5e-27 92.8 25.3 4.1e-05 23.9 0.3 8.2 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ11421.1 - 1.1e-22 79.5 26.6 3.2e-10 39.6 3.3 5.5 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 OAJ11421.1 - 1.8e-09 37.4 14.6 5.5e-05 22.7 0.2 4.5 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OAJ11421.1 - 2.6e-05 24.2 25.4 4.3 8.3 0.0 9.5 10 0 0 10 10 10 3 Leucine Rich Repeat BSP_II PF05432.11 OAJ11421.1 - 0.0031 17.3 1.8 0.0031 17.3 1.8 4.5 5 1 0 5 5 5 1 Bone sialoprotein II (BSP-II) LRR_6 PF13516.6 OAJ11421.1 - 0.012 15.7 28.9 0.69 10.1 0.3 8.9 8 1 1 9 9 9 0 Leucine Rich repeat PIF1 PF05970.14 OAJ11428.1 - 8.8e-103 344.3 0.0 1.1e-102 343.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ11428.1 - 3.7e-20 73.0 0.2 7.9e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ11428.1 - 1.6e-10 41.1 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 OAJ11428.1 - 1.6e-06 26.4 0.0 3.7e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 OAJ11428.1 - 0.00081 19.8 0.0 0.024 15.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAJ11428.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.12 OAJ11428.1 - 0.046 13.0 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 OAJ11428.1 - 0.08 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 OAJ11428.1 - 0.09 12.8 0.1 0.82 9.6 0.0 2.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OAJ11428.1 - 0.091 13.1 0.0 0.34 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF2528 PF10800.8 OAJ11438.1 - 0.2 12.2 1.9 12 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) GRP PF07172.11 OAJ11439.1 - 0.011 16.4 6.6 0.011 16.4 6.6 2.8 3 0 0 3 3 3 0 Glycine rich protein family Utp14 PF04615.13 OAJ11439.1 - 0.12 10.9 25.9 0.16 10.5 25.9 1.0 1 0 0 1 1 1 0 Utp14 protein Hpt PF01627.23 OAJ11451.1 - 1.3e-09 38.2 0.1 2.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Hpt domain Adeno_E1A PF02703.14 OAJ11451.1 - 0.003 17.2 0.3 0.003 17.2 0.3 1.9 1 1 1 2 2 2 1 Early E1A protein IPK PF03770.16 OAJ11452.1 - 5.8e-36 124.2 0.0 2.1e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase Ribonuc_red_lgC PF02867.15 OAJ11453.1 - 2.5e-182 607.1 0.0 3.1e-182 606.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAJ11453.1 - 3.2e-24 84.7 0.0 7.1e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAJ11453.1 - 6.4e-18 65.1 0.2 1.7e-17 63.8 0.2 1.8 1 0 0 1 1 1 1 ATP cone domain RVT_1 PF00078.27 OAJ11459.1 - 2.4e-31 109.0 0.0 3.6e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAJ11459.1 - 1.4e-05 25.3 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAJ11459.1 - 1.7e-05 24.6 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like SRF-TF PF00319.18 OAJ11459.1 - 0.03 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1232 PF06803.12 OAJ11459.1 - 0.22 11.4 2.9 0.55 10.1 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Exo_endo_phos_2 PF14529.6 OAJ11460.1 - 1.6e-10 40.9 0.0 5.2e-10 39.2 0.0 1.9 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ11460.1 - 2.4e-07 30.5 0.4 2e-06 27.5 0.1 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SRP54 PF00448.22 OAJ11460.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain WD40 PF00400.32 OAJ11462.1 - 2.3e-11 44.0 7.9 0.004 18.0 0.2 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11462.1 - 9.3e-06 25.9 0.0 0.05 13.9 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ11462.1 - 0.14 10.8 0.1 0.36 9.4 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Ras PF00071.22 OAJ11463.1 - 1e-53 181.3 0.0 1.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ11463.1 - 4e-19 69.0 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ11463.1 - 1.9e-06 27.4 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ11463.1 - 0.14 11.7 0.1 1.2 8.6 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF4442 PF14539.6 OAJ11473.1 - 0.068 13.3 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT PF03061.22 OAJ11473.1 - 0.068 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily DUF4218 PF13960.6 OAJ11474.1 - 0.00052 19.6 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RNA_pol_A_bac PF01000.26 OAJ11476.1 - 3.7e-27 94.9 0.0 5.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAJ11476.1 - 6.8e-19 67.1 0.0 9.2e-19 66.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_transf_28 PF03033.20 OAJ11485.1 - 2.4e-32 111.9 0.0 5.8e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAJ11485.1 - 3.6e-09 36.5 0.1 0.0024 17.7 0.0 3.6 4 0 0 4 4 4 2 GRAM domain UDPGT PF00201.18 OAJ11485.1 - 0.00067 18.6 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 OAJ11485.1 - 0.19 12.2 0.0 0.56 10.7 0.0 1.8 1 0 0 1 1 1 0 PH domain DUF423 PF04241.15 OAJ11486.1 - 9.6e-24 83.4 2.8 2.1e-23 82.3 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Trypsin PF00089.26 OAJ11496.1 - 0.074 12.9 0.1 0.074 12.9 0.1 1.1 1 0 0 1 1 1 0 Trypsin zf-P11 PF03854.14 OAJ11496.1 - 1.3 8.8 6.4 11 5.7 1.6 2.9 2 1 1 3 3 3 0 P-11 zinc finger Lon_C PF05362.13 OAJ11503.1 - 2.6e-05 23.9 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LigB PF02900.18 OAJ11505.1 - 1.2e-22 80.3 0.1 9.3e-16 57.7 0.1 2.1 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mrr_cat PF04471.12 OAJ11505.1 - 0.037 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease TMA7 PF09072.10 OAJ11506.1 - 0.64 10.9 5.0 2.2 9.2 5.0 1.9 1 0 0 1 1 1 0 Translation machinery associated TMA7 Transposase_21 PF02992.14 OAJ11514.1 - 4.5e-07 29.3 0.0 7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ11514.1 - 0.0059 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) BHD_2 PF10404.9 OAJ11514.1 - 0.16 12.9 0.5 0.51 11.3 0.5 1.9 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Histone PF00125.24 OAJ11523.1 - 2.4e-46 157.3 0.2 3.5e-46 156.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 NTP_transferase PF00483.23 OAJ11523.1 - 5.4e-15 55.7 0.0 9.9e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase CENP-T_C PF15511.6 OAJ11523.1 - 0.0029 17.7 0.1 0.0067 16.5 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ11523.1 - 0.0054 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein RVT_2 PF07727.14 OAJ11524.1 - 1.3e-70 237.9 0.0 1.7e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ11524.1 - 1.9e-15 57.1 0.6 4.9e-15 55.8 0.2 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OAJ11524.1 - 0.00031 20.5 0.4 0.011 15.5 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain DUF4889 PF16230.5 OAJ11524.1 - 7.4 6.9 7.0 29 5.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4889) RSN1_7TM PF02714.15 OAJ11525.1 - 4.4e-70 236.1 22.8 1e-69 234.9 22.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ11525.1 - 2.3e-36 125.6 0.0 4.4e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ11525.1 - 4.5e-36 124.0 0.9 4.5e-36 124.0 0.9 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Sm_multidrug_ex PF06695.11 OAJ11525.1 - 0.14 12.8 0.0 0.14 12.8 0.0 4.1 6 1 1 7 7 7 0 Putative small multi-drug export protein Baculo_11_kDa PF06143.11 OAJ11525.1 - 1 9.0 3.2 1.5 8.4 0.4 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family RhoGEF PF00621.20 OAJ11533.1 - 9.1e-13 48.8 0.0 3.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Esterase PF00756.20 OAJ11535.1 - 0.0004 20.1 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Asp2 PF16929.5 OAJ11535.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Dimer_Tnp_hAT PF05699.14 OAJ11547.1 - 5.3e-21 74.2 0.1 1e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5492 PF17596.2 OAJ11558.1 - 0.19 12.1 0.0 0.52 10.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5492) Retrotrans_gag PF03732.17 OAJ11560.1 - 6.5e-12 45.6 0.2 3.7e-11 43.2 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ11560.1 - 3.8e-08 33.2 0.0 6.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) PBECR2 PF18810.1 OAJ11560.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 DUF2205 PF10224.9 OAJ11560.1 - 0.17 11.9 1.4 0.37 10.8 1.4 1.5 1 0 0 1 1 1 0 Short coiled-coil protein TSC22 PF01166.18 OAJ11560.1 - 0.22 11.9 2.4 0.36 11.2 1.0 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4140 PF13600.6 OAJ11560.1 - 0.33 11.4 3.7 5.1 7.6 3.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 OAJ11560.1 - 0.54 10.9 2.1 0.68 10.6 0.2 2.1 2 0 0 2 2 2 0 Initiation control protein YabA RT_RNaseH PF17917.1 OAJ11561.1 - 5e-36 123.2 0.3 9.4e-36 122.3 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ11561.1 - 2.5e-35 120.5 0.1 6.6e-35 119.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ11561.1 - 1.3e-32 113.2 0.1 2.3e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ11561.1 - 5e-21 74.6 0.4 1.6e-20 72.9 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11561.1 - 7.5e-14 51.9 0.0 2.6e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAJ11561.1 - 1.4e-08 34.5 0.0 3.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 OAJ11561.1 - 8.7e-05 23.1 0.0 0.00023 21.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11561.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ11561.1 - 0.0012 19.0 0.0 0.0059 16.8 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 OAJ11561.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Pet100 PF09803.9 OAJ11572.1 - 7e-24 84.1 0.0 1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Pet100 SR-25 PF10500.9 OAJ11572.1 - 0.11 12.1 7.2 0.13 11.9 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hydrolase_6 PF13344.6 OAJ11573.1 - 1.7e-19 69.8 0.0 3.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ11573.1 - 2.1e-10 40.5 0.1 3.5e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAJ11573.1 - 4.3e-08 33.7 0.1 1.1e-06 29.1 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAJ11573.1 - 1.8e-06 28.1 1.1 0.0045 17.1 0.1 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 OAJ11573.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.10 OAJ11573.1 - 0.12 12.0 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Fcf1 PF04900.12 OAJ11574.1 - 1.8e-36 124.5 1.4 2.5e-36 124.0 1.4 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAJ11574.1 - 4.3e-11 43.1 0.0 5.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 PIN like domain Tannase PF07519.11 OAJ11575.1 - 3.7e-72 243.7 0.0 5.8e-64 216.7 0.0 2.7 2 1 0 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAJ11575.1 - 0.14 11.6 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family CLN3 PF02487.17 OAJ11576.1 - 5.5e-114 381.3 0.0 6.6e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 CLN3 protein Nop14 PF04147.12 OAJ11576.1 - 0.092 10.9 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ11576.1 - 6.6 4.7 6.5 11 4.0 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.19 OAJ11576.1 - 7.2 7.3 11.9 0.49 11.0 6.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein UreD PF01774.17 OAJ11577.1 - 4.9e-59 199.8 0.4 7.2e-59 199.3 0.4 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Forkhead PF00250.18 OAJ11586.1 - 1.3e-22 79.8 0.0 2.6e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain tRNA-synt_2d PF01409.20 OAJ11587.1 - 1.7e-86 289.7 0.0 2.3e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAJ11587.1 - 1.3e-14 54.2 1.3 2.4e-14 53.3 0.1 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 OAJ11587.1 - 5.8e-08 32.4 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OAJ11587.1 - 6.2e-05 22.2 0.3 0.0021 17.2 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OAJ11587.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 OAJ11587.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Dsh_C PF12316.8 OAJ11588.1 - 0.0053 17.2 9.1 0.0053 17.2 9.1 1.4 1 1 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal CAC1F_C PF16885.5 OAJ11588.1 - 0.12 12.1 4.7 0.14 11.8 4.7 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF89 PF01937.19 OAJ11599.1 - 1.1e-106 356.8 0.0 1.7e-106 356.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 TPR_19 PF14559.6 OAJ11599.1 - 0.026 15.0 0.5 0.076 13.5 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 OAJ11611.1 - 4.9e-14 52.5 6.8 0.014 16.2 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11611.1 - 3.4e-10 40.1 0.0 3.2e-05 24.2 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAJ11611.1 - 0.012 15.5 0.2 0.33 10.9 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Mg_trans_NIPA PF05653.14 OAJ11612.1 - 2.2e-105 352.0 17.3 2.6e-105 351.8 17.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAJ11612.1 - 5.1e-05 23.5 5.2 5.1e-05 23.5 5.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF3671 PF12420.8 OAJ11612.1 - 5.8 7.0 11.3 0.66 10.1 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function Ribosomal_L11_N PF03946.14 OAJ11613.1 - 5.7e-24 83.7 0.2 9.1e-24 83.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAJ11613.1 - 2.1e-16 60.2 0.1 3.8e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.8 OAJ11613.1 - 0.0088 16.2 0.8 0.015 15.5 0.8 1.3 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M URO-D PF01208.17 OAJ11614.1 - 1.4e-135 451.9 0.0 1.6e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Proton_antipo_N PF00662.20 OAJ11636.1 - 0.76 9.9 2.9 3.7 7.7 0.0 2.9 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus HMG_box PF00505.19 OAJ11638.1 - 9.4e-17 61.2 22.5 3.9e-09 36.8 1.1 3.7 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ11638.1 - 3.4e-14 53.2 15.7 8.4e-09 35.9 0.5 2.8 3 0 0 3 3 3 2 HMG-box domain adh_short PF00106.25 OAJ11639.1 - 6.4e-29 100.8 0.0 8.9e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11639.1 - 2.2e-16 60.1 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ11639.1 - 2.9e-08 33.9 0.8 8.5e-08 32.3 0.8 1.7 1 1 0 1 1 1 1 KR domain DUF5546 PF17700.1 OAJ11639.1 - 0.061 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5546) RT_RNaseH_2 PF17919.1 OAJ11646.1 - 1.6e-17 63.3 0.0 3.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11646.1 - 4.1e-16 59.2 0.0 1.6e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 OAJ11646.1 - 1e-15 57.9 0.0 2.5e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11646.1 - 3.1e-15 56.0 0.3 5.9e-15 55.1 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OAJ11646.1 - 1.2e-08 35.4 0.0 2.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ11646.1 - 2e-08 34.8 0.0 4.9e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAJ11646.1 - 1.3e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 OAJ11646.1 - 3.7e-05 23.5 0.1 7.1e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage_integrase PF00589.22 OAJ11646.1 - 0.0027 17.5 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RVP PF00077.20 OAJ11646.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_IS240 PF13610.6 OAJ11646.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 DDE domain RVP_2 PF08284.11 OAJ11646.1 - 0.082 12.7 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease Uds1 PF15456.6 OAJ11657.1 - 0.002 18.3 0.7 0.0031 17.7 0.7 1.3 1 0 0 1 1 1 1 Up-regulated During Septation Rx_N PF18052.1 OAJ11657.1 - 0.0093 16.2 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Rx N-terminal domain bZIP_1 PF00170.21 OAJ11657.1 - 0.017 15.2 2.1 0.048 13.8 0.6 2.1 1 1 1 2 2 2 0 bZIP transcription factor Spectrin PF00435.21 OAJ11657.1 - 0.031 14.8 0.5 0.057 13.9 0.5 1.4 1 0 0 1 1 1 0 Spectrin repeat Tropomyosin_1 PF12718.7 OAJ11657.1 - 0.038 14.1 1.2 0.054 13.6 1.2 1.1 1 0 0 1 1 1 0 Tropomyosin like Fzo_mitofusin PF04799.13 OAJ11657.1 - 0.11 12.0 1.4 0.26 10.8 1.4 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF3138 PF11336.8 OAJ11657.1 - 0.23 10.0 0.5 0.3 9.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DDE_3 PF13358.6 OAJ11659.1 - 5.5e-29 100.8 0.0 9.1e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ11659.1 - 4.5e-08 32.6 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ11659.1 - 5.3e-07 30.2 0.1 6.8e-06 26.6 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 OAJ11659.1 - 2.5e-05 23.4 0.0 0.073 12.0 0.0 2.2 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 OAJ11659.1 - 0.00014 22.0 0.5 0.0026 18.0 0.1 2.4 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.19 OAJ11659.1 - 0.0021 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 OAJ11659.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 OAJ11659.1 - 0.022 14.8 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_ABP1_N PF18107.1 OAJ11659.1 - 0.056 13.2 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Mga PF05043.13 OAJ11659.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF3439 PF11921.8 OAJ11660.1 - 0.17 11.9 1.7 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pantoate_ligase PF02569.15 OAJ11671.1 - 2.4e-88 295.8 0.0 5.7e-88 294.6 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase PPR_2 PF13041.6 OAJ11672.1 - 1.6e-13 50.6 0.0 0.0094 16.1 0.0 6.3 5 1 1 6 6 6 4 PPR repeat family PPR_1 PF12854.7 OAJ11672.1 - 1.2e-07 31.3 1.7 0.12 12.1 0.0 5.5 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 OAJ11672.1 - 1.7e-06 28.0 0.0 1 9.5 0.0 4.5 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 OAJ11672.1 - 7.3e-06 25.9 7.4 0.069 13.4 0.0 5.8 5 1 0 5 5 5 2 PPR repeat PPR_long PF17177.4 OAJ11672.1 - 0.00014 21.3 0.3 0.086 12.2 0.0 3.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP EIN3 PF04873.13 OAJ11672.1 - 0.0057 16.0 0.5 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Ethylene insensitive 3 TPR_14 PF13428.6 OAJ11672.1 - 0.055 14.3 8.8 69 4.7 0.2 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RhoGEF PF00621.20 OAJ11681.1 - 6.9e-28 98.1 0.2 1.1e-27 97.4 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain SpoIIIAH PF12685.7 OAJ11681.1 - 0.18 11.6 2.0 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein PRIMA1 PF16101.5 OAJ11681.1 - 5.5 7.1 13.8 0.034 14.2 1.3 3.3 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 TRAPP PF04051.16 OAJ11682.1 - 4.2e-40 136.8 0.0 5e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component eIF3_N PF09440.10 OAJ11683.1 - 2.2e-40 138.2 2.1 4.4e-40 137.2 0.5 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAJ11683.1 - 3.3e-10 40.4 0.1 6.6e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 OAJ11683.1 - 0.036 14.3 0.3 1.4 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ11683.1 - 0.86 9.9 3.8 4.5 7.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GATA PF00320.27 OAJ11684.1 - 2.6e-12 46.1 12.5 6.6e-07 28.8 3.5 2.4 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 OAJ11684.1 - 0.00025 21.1 0.7 0.18 11.9 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Vps36-NZF-N PF16988.5 OAJ11684.1 - 0.078 12.4 4.9 3.6 7.0 0.5 3.4 2 2 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TF_Zn_Ribbon PF08271.12 OAJ11684.1 - 6.5 6.4 11.7 2.3 7.8 0.3 3.1 3 1 0 3 3 3 0 TFIIB zinc-binding Phytase PF02333.15 OAJ11684.1 - 8.9 5.2 8.5 15 4.4 8.5 1.3 1 0 0 1 1 1 0 Phytase ALS_ss_C PF10369.9 OAJ11692.1 - 2.8e-18 65.9 0.0 2.3e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAJ11692.1 - 5.6e-13 48.4 0.1 9.7e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 OAJ11692.1 - 1.2e-07 31.5 0.1 3.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 ACT domain MEIOC PF15189.6 OAJ11692.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC SOG2 PF10428.9 OAJ11692.1 - 0.65 9.1 9.8 1 8.5 9.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3827 PF12877.7 OAJ11692.1 - 1.6 7.0 4.4 2.4 6.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ribosomal_L5_C PF00673.21 OAJ11694.1 - 4.7e-20 71.6 0.0 8.7e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAJ11694.1 - 3.2e-19 69.0 0.0 9e-19 67.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Prefoldin_2 PF01920.20 OAJ11695.1 - 3.1e-21 75.3 14.1 4e-21 74.9 14.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 OAJ11695.1 - 9.9e-05 22.7 5.6 0.068 13.6 0.1 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 OAJ11695.1 - 0.011 16.2 17.1 0.051 14.1 5.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region OmdA PF13376.6 OAJ11695.1 - 0.028 14.4 0.2 0.075 13.1 0.2 1.9 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated SlyX PF04102.12 OAJ11695.1 - 0.03 15.0 1.2 0.03 15.0 1.2 2.5 2 1 0 2 2 2 0 SlyX Lzipper-MIP1 PF14389.6 OAJ11695.1 - 0.053 13.8 9.5 0.33 11.3 7.9 2.3 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 OAJ11695.1 - 0.061 13.5 12.5 0.6 10.3 12.5 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 OAJ11695.1 - 0.069 13.2 14.6 0.44 10.7 2.2 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 OAJ11695.1 - 0.085 11.4 13.1 0.099 11.2 13.1 1.0 1 0 0 1 1 1 0 Macoilin family Med4 PF10018.9 OAJ11695.1 - 0.086 12.5 0.2 0.086 12.5 0.2 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 UPF0242 PF06785.11 OAJ11695.1 - 0.089 12.9 15.2 0.13 12.3 15.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AATF-Che1 PF13339.6 OAJ11695.1 - 0.1 13.3 7.3 0.17 12.6 7.2 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.6 OAJ11695.1 - 0.13 11.6 12.9 0.049 13.0 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FPP PF05911.11 OAJ11695.1 - 0.14 10.3 12.8 0.17 10.0 12.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 OAJ11695.1 - 0.17 10.7 17.2 0.3 9.9 17.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Nas2_N PF18265.1 OAJ11695.1 - 0.18 11.7 3.1 1.3 9.0 0.1 2.8 2 2 0 2 2 2 0 Nas2 N_terminal domain FlxA PF14282.6 OAJ11695.1 - 0.19 11.7 15.7 0.28 11.2 2.0 2.2 2 0 0 2 2 2 0 FlxA-like protein IHO1 PF15771.5 OAJ11695.1 - 0.2 10.4 7.4 0.045 12.5 3.8 1.5 1 1 0 2 2 2 0 Interactor of HORMAD1 protein 1 Tmpp129 PF10272.9 OAJ11695.1 - 0.21 10.9 3.8 0.14 11.4 0.7 1.8 1 1 1 2 2 2 0 Putative transmembrane protein precursor Cep57_MT_bd PF06657.13 OAJ11695.1 - 0.23 11.9 10.0 0.34 11.4 1.7 2.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.10 OAJ11695.1 - 0.25 11.2 1.9 8.4 6.3 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 kleA_kleC PF17383.2 OAJ11695.1 - 0.33 11.3 2.9 0.53 10.6 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A KMP11 PF03037.16 OAJ11695.1 - 0.44 11.4 4.4 1.6 9.6 4.4 1.9 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1664 PF07889.12 OAJ11695.1 - 0.45 10.6 8.7 1.3 9.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 OAJ11695.1 - 0.46 10.7 14.6 2.6 8.3 3.6 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Uds1 PF15456.6 OAJ11695.1 - 0.56 10.4 9.2 1.1 9.4 9.2 1.7 1 1 0 1 1 1 0 Up-regulated During Septation JIP_LZII PF16471.5 OAJ11695.1 - 0.57 10.4 9.4 0.16 12.2 0.9 2.7 2 1 1 3 3 2 0 JNK-interacting protein leucine zipper II Occludin_ELL PF07303.13 OAJ11695.1 - 0.61 10.9 7.5 3 8.6 1.7 2.2 1 1 1 2 2 2 0 Occludin homology domain Atg14 PF10186.9 OAJ11695.1 - 0.63 9.1 10.2 1.5 7.9 10.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 OAJ11695.1 - 0.66 9.3 18.6 2.9 7.2 18.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 OAJ11695.1 - 0.72 9.8 11.4 2.9 7.9 11.4 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF5082 PF16888.5 OAJ11695.1 - 0.73 10.1 11.4 2.1 8.7 11.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 OAJ11695.1 - 0.82 9.0 10.6 6.9 6.0 10.7 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus V-ATPase_C PF03223.15 OAJ11695.1 - 0.85 9.0 7.6 1.4 8.3 7.6 1.3 1 1 0 1 1 1 0 V-ATPase subunit C Baculo_PEP_C PF04513.12 OAJ11695.1 - 0.93 9.5 6.7 2.1 8.4 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 OAJ11695.1 - 0.94 9.5 11.2 0.41 10.7 1.6 2.1 1 1 1 2 2 2 0 Laminin Domain II PKcGMP_CC PF16808.5 OAJ11695.1 - 0.95 9.4 7.2 0.18 11.7 1.6 2.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HR1 PF02185.16 OAJ11695.1 - 1.2 9.3 10.8 4.6 7.4 0.9 2.5 2 1 0 2 2 2 0 Hr1 repeat End3 PF12761.7 OAJ11695.1 - 1.2 9.2 12.3 1.5 9.0 12.3 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Peptidase_S46 PF10459.9 OAJ11695.1 - 1.2 7.7 8.1 1.5 7.4 8.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF724 PF05266.14 OAJ11695.1 - 1.4 8.7 14.4 91 2.8 14.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 OAJ11695.1 - 1.4 9.6 11.0 2.2e+02 2.5 11.0 2.1 1 1 0 1 1 1 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OAJ11695.1 - 1.8 8.6 15.5 0.96 9.5 6.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mto2_bdg PF12808.7 OAJ11695.1 - 2 8.7 10.0 14 6.1 0.5 3.5 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2205 PF10224.9 OAJ11695.1 - 2.1 8.4 16.0 0.1 12.6 3.4 2.4 1 1 1 2 2 2 0 Short coiled-coil protein DUF641 PF04859.12 OAJ11695.1 - 2.5 8.5 13.2 0.95 9.8 5.3 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Phlebovirus_NSM PF07246.11 OAJ11695.1 - 2.7 7.3 7.0 3.6 6.9 7.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DHR10 PF18595.1 OAJ11695.1 - 2.8 8.0 17.5 11 6.2 17.5 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 OAJ11695.1 - 3 8.3 12.5 3 8.3 10.7 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 OAJ11695.1 - 3 8.2 16.2 3.2 8.1 2.1 2.1 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPD52 PF04201.15 OAJ11695.1 - 3.4 7.2 9.2 0.58 9.7 2.5 2.2 1 1 1 2 2 2 0 Tumour protein D52 family Allexi_40kDa PF05549.11 OAJ11695.1 - 4.1 6.8 6.5 2.3 7.6 2.3 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spc24 PF08286.11 OAJ11695.1 - 4.6 7.5 15.0 5.4 7.3 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 OAJ11695.1 - 4.9 7.5 15.6 8.2 6.8 2.6 3.2 2 2 1 3 3 3 0 ABC transporter C-terminal domain OmpH PF03938.14 OAJ11695.1 - 6.2 7.2 20.4 27 5.1 20.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 OAJ11695.1 - 6.5 6.7 15.0 0.96 9.4 4.5 2.7 2 1 1 3 3 3 0 Prefoldin subunit FYVE PF01363.21 OAJ11696.1 - 1.9e-19 69.6 0.2 3.7e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 OAJ11696.1 - 1.1e-09 37.9 0.8 1.1e-09 37.9 0.8 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Zn-C2H2_12 PF18112.1 OAJ11696.1 - 0.35 11.4 1.3 1.5 9.4 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 OAJ11696.1 - 2.5 8.2 4.8 1.7 8.8 1.9 2.0 2 0 0 2 2 2 0 Double zinc ribbon UQ_con PF00179.26 OAJ11697.1 - 8.4e-50 168.1 0.0 1.1e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ11697.1 - 0.00017 21.3 0.0 0.00036 20.2 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B Acetyltransf_1 PF00583.25 OAJ11698.1 - 4.5e-14 52.7 0.0 5.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ11698.1 - 4.9e-08 33.0 0.0 5.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ11698.1 - 1.2e-06 28.8 0.1 1.6e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ11698.1 - 0.00059 19.8 0.0 0.00092 19.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAJ11698.1 - 0.0051 16.9 0.1 0.01 15.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAJ11698.1 - 0.12 11.9 0.2 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase Thiolase_N PF00108.23 OAJ11709.1 - 1.1e-14 54.5 0.9 1.5e-12 47.4 0.0 2.8 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ11709.1 - 1.6e-11 43.9 0.6 1.3e-10 41.0 0.3 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ11709.1 - 0.002 17.7 4.5 0.19 11.2 1.6 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ11709.1 - 0.0039 17.0 1.5 0.07 13.0 0.5 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 OAJ11709.1 - 0.017 15.1 0.7 0.11 12.5 0.7 2.4 1 1 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain GST_N PF02798.20 OAJ11710.1 - 4.8e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ11710.1 - 1.3e-10 41.4 0.0 2.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ11710.1 - 4.2e-10 39.9 0.0 8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ11710.1 - 8.3e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ11710.1 - 5e-09 36.3 0.1 8.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ11710.1 - 7.6e-07 29.1 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hexokinase_2 PF03727.16 OAJ11711.1 - 6.4e-70 235.3 0.0 8.3e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAJ11711.1 - 2.6e-69 233.1 0.0 3.7e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MCM PF00493.23 OAJ11712.1 - 3.3e-101 337.1 0.0 4.9e-101 336.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ11712.1 - 6.1e-29 100.4 0.1 1e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ11712.1 - 6.3e-20 71.4 0.8 1.5e-19 70.2 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ11712.1 - 8.7e-14 52.0 0.0 2.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OAJ11712.1 - 1.1e-07 31.9 0.0 2.1e-05 24.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ11712.1 - 7.1e-07 28.8 0.0 5.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 OAJ11712.1 - 0.0051 17.4 0.5 0.016 15.8 0.5 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 OAJ11712.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 OAJ11712.1 - 0.03 14.2 0.9 0.099 12.5 0.9 1.9 1 0 0 1 1 1 0 AAA lid domain PBP1_TM PF14812.6 OAJ11712.1 - 6.7 7.2 7.1 2.7 8.4 0.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-BED PF02892.15 OAJ11723.1 - 0.0035 17.3 1.0 0.0096 15.9 1.0 1.7 1 0 0 1 1 1 1 BED zinc finger BUD22 PF09073.10 OAJ11724.1 - 2.2 7.5 13.5 3.8 6.8 13.5 1.3 1 0 0 1 1 1 0 BUD22 RVT_1 PF00078.27 OAJ11739.1 - 5.3e-19 68.6 0.0 9.7e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Baculo_PEP_C PF04513.12 OAJ11747.1 - 4.8e-05 23.4 11.1 0.0016 18.5 0.4 3.5 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Het-C PF07217.11 OAJ11747.1 - 0.0033 16.0 0.6 0.0033 16.0 0.6 1.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein Het-C STAT_alpha PF01017.20 OAJ11747.1 - 0.005 16.8 3.6 0.18 11.7 0.3 2.4 2 0 0 2 2 2 1 STAT protein, all-alpha domain Syntaxin PF00804.25 OAJ11747.1 - 0.011 15.4 5.0 0.18 11.4 1.1 2.2 2 0 0 2 2 2 0 Syntaxin Filament PF00038.21 OAJ11747.1 - 0.032 13.8 1.3 4.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein PIN_2 PF10130.9 OAJ11747.1 - 0.059 13.6 1.0 1.6 9.0 0.2 2.6 2 0 0 2 2 2 0 PIN domain HAUS-augmin3 PF14932.6 OAJ11747.1 - 0.062 12.9 10.0 0.049 13.2 2.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin-6_N PF09177.11 OAJ11747.1 - 0.079 13.5 3.7 2.9 8.5 0.8 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 OAJ11747.1 - 0.14 12.9 5.6 0.15 12.8 1.4 2.3 2 0 0 2 2 2 0 Occludin homology domain DUF4634 PF15465.6 OAJ11747.1 - 0.16 12.3 0.4 0.34 11.2 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4634) RmuC PF02646.16 OAJ11747.1 - 0.27 10.3 6.8 0.66 9.0 2.7 2.3 2 0 0 2 2 2 0 RmuC family TMPIT PF07851.13 OAJ11747.1 - 0.69 9.1 5.9 2.8 7.1 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 OAJ11747.1 - 0.74 9.9 8.1 1.9 8.6 1.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OAJ11747.1 - 0.85 9.8 4.4 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SurA_N_3 PF13624.6 OAJ11747.1 - 1.2 8.8 4.9 0.25 11.1 0.4 2.0 3 0 0 3 3 3 0 SurA N-terminal domain APG6_N PF17675.1 OAJ11747.1 - 1.3 9.5 9.5 5.3 7.6 1.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 OAJ11747.1 - 1.4 8.5 8.6 0.32 10.6 0.4 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HIP1_clath_bdg PF16515.5 OAJ11747.1 - 1.7 9.3 8.7 5.1 7.8 0.9 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Carbpep_Y_N PF05388.11 OAJ11747.1 - 2.9 8.5 6.1 2 8.9 1.9 2.5 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide RRN3 PF05327.11 OAJ11747.1 - 4.2 5.8 6.4 13 4.2 1.9 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Seryl_tRNA_N PF02403.22 OAJ11747.1 - 5.3 7.3 8.8 9.3 6.5 0.6 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 OAJ11747.1 - 6.9 7.0 10.0 18 5.7 2.3 2.6 2 0 0 2 2 2 0 YlqD protein Lectin_N PF03954.14 OAJ11747.1 - 7.6 6.3 8.4 5.2 6.8 1.5 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Sugar_tr PF00083.24 OAJ11748.1 - 1.4e-39 136.2 21.4 4.2e-38 131.4 21.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ11748.1 - 3.1e-16 59.3 39.6 8.9e-12 44.6 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAJ11748.1 - 8.9e-06 24.5 5.7 8.9e-06 24.5 5.7 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein BT1 PF03092.16 OAJ11748.1 - 0.0033 15.7 1.0 0.74 8.0 0.0 2.5 2 0 0 2 2 2 2 BT1 family DUF2256 PF10013.9 OAJ11749.1 - 4.7e-14 52.2 4.5 8.6e-14 51.4 4.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) DNA_pol_viral_C PF00336.18 OAJ11750.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.22 OAJ11751.1 - 0.00028 20.7 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family MULE PF10551.9 OAJ11761.1 - 8.5e-10 38.9 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ11761.1 - 2.9e-05 23.6 0.2 6.5e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF3860 PF12976.7 OAJ11761.1 - 0.036 14.1 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) TssD PF17642.1 OAJ11761.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Hemolysin coregulated protein Hcp (TssD) Spore_III_AB PF09548.10 OAJ11761.1 - 0.085 13.0 3.5 0.19 11.9 3.5 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4200 PF13863.6 OAJ11761.1 - 1.2 9.5 10.8 1.1 9.6 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) G-alpha PF00503.20 OAJ11762.1 - 7.3e-74 249.0 0.0 4.1e-55 187.4 0.0 2.8 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 OAJ11762.1 - 8.4e-10 38.4 0.0 1.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ11762.1 - 0.0016 18.8 0.1 0.024 15.0 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ11762.1 - 0.0042 17.4 0.0 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ11762.1 - 0.0068 16.1 0.0 0.094 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAJ11762.1 - 0.0073 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 OAJ11762.1 - 0.025 13.8 0.0 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 OAJ11762.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 OAJ11762.1 - 0.07 13.3 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ11762.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ11762.1 - 0.12 11.9 0.0 1.1 8.9 0.0 2.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ArfGap PF01412.18 OAJ11764.1 - 5.5e-40 136.1 1.6 8.2e-40 135.5 1.6 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Spo12 PF05032.12 OAJ11775.1 - 9.5e-14 51.0 5.0 2.1e-13 49.9 5.0 1.6 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.7 OAJ11775.1 - 0.00087 19.9 0.1 0.0014 19.2 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain ubiquitin PF00240.23 OAJ11776.1 - 8.6e-25 86.3 0.1 9.5e-25 86.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ11776.1 - 1.2e-13 50.7 0.0 1.3e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ11776.1 - 0.0004 20.8 0.0 0.00048 20.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ11776.1 - 0.0038 17.1 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HATPase_c PF02518.26 OAJ11776.1 - 0.016 15.7 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIB PF00382.19 OAJ11777.1 - 1.2e-26 92.5 0.0 5.1e-18 64.9 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAJ11777.1 - 1.4e-26 92.7 3.5 1.4e-26 92.7 3.5 4.2 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 OAJ11777.1 - 8.8e-08 31.5 1.2 1.7e-07 30.6 1.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OAJ11777.1 - 5.9e-05 22.8 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain CDC27 PF09507.10 OAJ11777.1 - 0.00097 18.6 7.4 0.00097 18.6 7.4 3.8 2 1 1 3 3 3 1 DNA polymerase subunit Cdc27 Ribosomal_S27e PF01667.17 OAJ11777.1 - 0.09 12.5 0.9 0.16 11.7 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.13 OAJ11777.1 - 2.5 7.8 4.0 5.4 6.8 4.0 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Cpn60_TCP1 PF00118.24 OAJ11778.1 - 6e-157 523.2 0.8 7.2e-157 522.9 0.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 OAJ11779.1 - 4e-17 62.3 5.2 6.2e-05 23.7 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PD40 PF07676.12 OAJ11779.1 - 0.012 15.5 0.9 0.044 13.7 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 OAJ11779.1 - 0.019 15.3 0.0 22 5.4 0.0 4.3 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_31 PF13847.6 OAJ11780.1 - 9.8e-15 54.7 0.0 1.9e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ11780.1 - 2.3e-06 28.2 0.0 9e-06 26.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ11780.1 - 1.1e-05 26.1 0.0 2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAJ11780.1 - 0.00011 22.3 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ11780.1 - 0.00031 20.6 0.0 0.00071 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ11780.1 - 0.00091 19.8 0.0 0.016 15.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain MetW PF07021.12 OAJ11780.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Las1 PF04031.13 OAJ11781.1 - 1.3e-42 145.5 0.2 1.6e-42 145.2 0.2 1.1 1 0 0 1 1 1 1 Las1-like zf-C2H2 PF00096.26 OAJ11791.1 - 0.00029 21.1 9.2 0.00079 19.7 1.9 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ11791.1 - 0.0021 18.4 3.6 0.0021 18.4 3.6 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ11791.1 - 0.013 16.2 14.6 0.11 13.4 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Opi1 PF08618.10 OAJ11792.1 - 5.8e-62 210.3 4.3 5.8e-62 210.3 4.3 4.0 3 2 0 3 3 3 1 Transcription factor Opi1 Helicase_C_2 PF13307.6 OAJ11811.1 - 2.5e-37 128.7 0.0 4.4e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain NADH_dehy_S2_C PF06444.11 OAJ11811.1 - 0.16 12.5 1.8 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus Sen15 PF09631.10 OAJ11812.1 - 2.6e-11 43.7 0.0 9.8e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein CTU2 PF10288.9 OAJ11813.1 - 7.7e-18 64.8 0.3 7.7e-18 64.8 0.3 2.3 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 MIP PF00230.20 OAJ11814.1 - 4e-36 124.8 11.6 5.4e-36 124.4 11.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein PTPS_related PF10131.9 OAJ11814.1 - 0.033 12.5 0.5 0.052 11.9 0.5 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein FixQ PF05545.11 OAJ11814.1 - 0.17 11.8 1.5 0.56 10.2 1.5 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RCC1 PF00415.18 OAJ11815.1 - 1.4e-21 76.8 13.3 2.3e-05 24.9 1.0 7.0 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ11815.1 - 7.1e-14 51.2 30.4 7.6e-11 41.5 0.4 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAJ11816.1 - 9.5e-13 47.8 2.7 3.1e-12 46.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ11816.1 - 4e-09 36.1 1.6 1.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAJ11816.1 - 0.013 15.3 0.0 0.031 14.2 0.0 1.6 2 0 0 2 2 2 0 F-box RXT2_N PF08595.11 OAJ11816.1 - 0.14 12.2 4.1 5.6 7.0 0.0 2.1 1 1 1 2 2 2 0 RXT2-like, N-terminal DASH_Dam1 PF08653.10 OAJ11817.1 - 1.1e-18 66.8 0.2 1.7e-18 66.1 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 RPN6_N PF18055.1 OAJ11826.1 - 4.8e-41 139.8 4.6 2.6e-40 137.4 2.2 2.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAJ11826.1 - 4.4e-20 72.2 0.1 1.5e-19 70.4 0.1 2.0 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 OAJ11826.1 - 8.8e-14 50.9 0.4 2.2e-13 49.7 0.4 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Alkyl_sulf_dimr PF14863.6 OAJ11826.1 - 0.006 17.0 2.7 0.1 13.0 0.6 3.3 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation DUF627 PF04781.12 OAJ11826.1 - 0.013 15.5 1.4 2.3 8.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_16 PF13432.6 OAJ11826.1 - 0.054 14.1 15.6 3 8.6 0.0 4.5 3 2 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ11826.1 - 0.065 13.5 2.0 3.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAJ11826.1 - 0.079 13.6 6.6 27 5.7 0.2 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat ICAT PF06384.11 OAJ11826.1 - 0.098 12.9 0.3 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT TPR_21 PF09976.9 OAJ11826.1 - 0.33 10.6 12.7 0.99 9.1 4.7 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 OAJ11826.1 - 0.44 11.5 12.9 3.7 8.6 1.4 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Pribosyltran PF00156.27 OAJ11827.1 - 1.3e-15 57.3 0.1 1.7e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAJ11827.1 - 0.0045 16.4 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NAD_binding_11 PF14833.6 OAJ11829.1 - 1.6e-06 28.3 0.1 2.8e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Aminotran_1_2 PF00155.21 OAJ11831.1 - 6.8e-17 61.7 0.0 3.8e-15 55.9 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II SecY PF00344.20 OAJ11831.1 - 5.7e-13 48.8 0.0 9.1e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 SecY translocase RPN7 PF10602.9 OAJ11832.1 - 7.2e-52 175.6 1.6 1e-51 175.1 1.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAJ11832.1 - 1.1e-13 51.5 0.0 2.9e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain ANAPC8 PF04049.13 OAJ11832.1 - 0.093 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 RasGEF PF00617.19 OAJ11841.1 - 6.8e-41 140.4 0.1 1.1e-40 139.7 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ11841.1 - 1.6e-06 28.3 0.1 3.6e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 OAJ11841.1 - 0.00073 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OAJ11841.1 - 0.036 13.5 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Aminotran_1_2 PF00155.21 OAJ11842.1 - 3.4e-36 125.2 0.0 6.5e-36 124.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ11842.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 OAJ11842.1 - 0.047 12.5 0.0 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Dimer_Tnp_hAT PF05699.14 OAJ11852.1 - 2.1e-15 56.3 0.0 4.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 OAJ11853.1 - 3.7e-38 131.4 0.0 5.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RVT_1 PF00078.27 OAJ11853.1 - 3.5e-23 82.3 0.0 6.4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 OAJ11853.1 - 4.2e-20 72.1 0.0 6.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Integrase_H2C2 PF17921.1 OAJ11853.1 - 9.4e-14 51.3 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11853.1 - 5.7e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ11853.1 - 7.3e-12 45.2 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RTC4 PF14474.6 OAJ11853.1 - 1.1e-05 25.5 0.0 5.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 RTC4-like domain APH PF01636.23 OAJ11853.1 - 0.0028 17.6 2.7 0.015 15.2 0.0 3.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family RT_RNaseH PF17917.1 OAJ11853.1 - 0.019 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pox_ser-thr_kin PF05445.11 OAJ11853.1 - 0.051 12.5 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAJ11853.1 - 0.097 12.0 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp_protease_2 PF13650.6 OAJ11854.1 - 0.0021 18.7 0.0 0.0045 17.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11854.1 - 0.0029 18.1 0.1 0.023 15.2 0.1 2.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease OTT_1508_deam PF14441.6 OAJ11866.1 - 2e-05 24.5 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.23 OAJ11866.1 - 0.0037 17.1 0.9 0.0071 16.2 0.2 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-MYND PF01753.18 OAJ11867.1 - 2.7e-05 24.2 18.9 5.5e-05 23.2 18.9 1.6 1 1 0 1 1 1 1 MYND finger Lipocalin_9 PF17186.4 OAJ11867.1 - 0.11 12.8 0.6 0.29 11.4 0.4 1.8 2 0 0 2 2 2 0 Lipocalin-like domain DUF1129 PF06570.11 OAJ11868.1 - 0.39 10.2 5.1 8.4 5.8 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Pilin_N PF07790.11 OAJ11868.1 - 2.5 9.1 10.9 4.1 8.4 0.1 2.8 2 1 1 3 3 3 0 Archaeal Type IV pilin, N-terminal PrmA PF06325.13 OAJ11876.1 - 8.5e-10 38.5 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAJ11876.1 - 1.1e-06 29.2 0.0 2.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ11876.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ11876.1 - 0.00015 22.4 0.0 0.00038 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ11876.1 - 0.00038 20.3 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ11876.1 - 0.0037 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAJ11876.1 - 0.024 15.4 1.4 0.1 13.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAJ11876.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 OAJ11876.1 - 0.054 12.4 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 OAJ11876.1 - 0.074 14.1 0.0 0.2 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FAM176 PF14851.6 OAJ11876.1 - 3.3 7.3 4.8 7.1 6.3 3.6 2.1 2 0 0 2 2 2 0 FAM176 family DUF2457 PF10446.9 OAJ11876.1 - 4.4 6.3 11.9 9.6 5.2 11.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nt_Gln_amidase PF09764.9 OAJ11877.1 - 7.1e-34 117.0 0.0 2e-32 112.3 0.0 2.9 1 1 0 1 1 1 1 N-terminal glutamine amidase NAD_binding_10 PF13460.6 OAJ11878.1 - 3.7e-12 46.5 0.0 7.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ11878.1 - 3.9e-11 42.9 0.0 1e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAJ11878.1 - 4.5e-11 42.8 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAJ11878.1 - 1.4e-10 40.7 0.0 6.5e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ11878.1 - 1.2e-07 31.2 0.0 8e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAJ11878.1 - 9.5e-07 28.2 0.1 0.039 13.1 0.0 2.6 1 1 2 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ11878.1 - 4.8e-05 22.9 0.0 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAJ11878.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11878.1 - 0.0073 15.9 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ11878.1 - 0.0079 16.1 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAJ11878.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arginase PF00491.21 OAJ11879.1 - 2e-73 247.3 0.0 2.4e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Ank_4 PF13637.6 OAJ11885.1 - 3.1e-08 34.0 0.0 0.00049 20.6 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ11885.1 - 3.7e-08 33.8 0.0 5.9e-07 30.0 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ11885.1 - 0.0017 18.6 0.1 5.7 7.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAJ11885.1 - 0.0021 18.4 0.0 2.1 8.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAJ11885.1 - 0.0021 18.4 0.0 21 6.1 0.0 4.8 5 1 0 5 5 5 1 Ankyrin repeat LysM PF01476.20 OAJ11886.1 - 6.3e-48 160.6 5.0 7.8e-12 45.1 0.0 6.6 6 0 0 6 6 6 6 LysM domain EF-hand_6 PF13405.6 OAJ11886.1 - 2.5e-08 33.2 0.0 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ11886.1 - 1.3e-07 30.7 0.2 0.013 15.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAJ11886.1 - 6.9e-07 28.5 1.9 0.0095 15.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAJ11886.1 - 9.1e-06 26.0 0.0 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OAJ11886.1 - 0.2 11.6 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Sporozoite_P67 PF05642.11 OAJ11886.1 - 8.1 4.4 9.1 18 3.2 9.1 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_18 PF00704.28 OAJ11887.1 - 7.7e-72 242.7 2.2 9.4e-72 242.4 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HRM PF02793.22 OAJ11887.1 - 0.0025 18.1 0.2 0.0071 16.6 0.2 1.8 1 0 0 1 1 1 1 Hormone receptor domain Sushi PF00084.20 OAJ11887.1 - 0.027 15.1 0.3 0.062 13.9 0.3 1.6 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) IL13 PF03487.13 OAJ11887.1 - 0.061 13.1 0.2 1.7 8.4 0.0 2.2 1 1 1 2 2 2 0 Interleukin-13 Chitin_bind_1 PF00187.19 OAJ11887.1 - 0.13 12.8 1.6 0.31 11.5 1.6 1.6 1 0 0 1 1 1 0 Chitin recognition protein HSP70 PF00012.20 OAJ11892.1 - 6.1e-29 100.7 0.1 7.7e-29 100.3 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein PSS PF03034.15 OAJ11892.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Phosphatidyl serine synthase MmgE_PrpD PF03972.14 OAJ11894.1 - 3.6e-90 302.6 2.8 6.9e-53 179.8 0.2 2.3 1 1 1 2 2 2 2 MmgE/PrpD family MHC_II_beta PF00969.19 OAJ11894.1 - 0.095 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain GATA PF00320.27 OAJ11905.1 - 6.6e-14 51.2 6.5 1.8e-13 49.9 6.5 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAJ11905.1 - 0.0014 18.9 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold FAM76 PF16046.5 OAJ11905.1 - 0.14 11.5 0.3 0.29 10.4 0.3 1.4 1 0 0 1 1 1 0 FAM76 protein FMO-like PF00743.19 OAJ11906.1 - 4e-21 75.0 0.0 1.1e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAJ11906.1 - 2.7e-12 46.6 1.0 1.1e-08 34.7 1.2 2.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ11906.1 - 5.1e-12 45.7 0.2 1.6e-09 37.5 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ11906.1 - 1.5e-10 40.7 0.8 5.6e-08 32.3 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ11906.1 - 2.5e-08 34.0 0.9 1.1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OAJ11906.1 - 1.3e-06 27.9 1.2 0.015 14.6 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAJ11906.1 - 1.9e-05 25.1 2.4 0.045 14.3 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ11906.1 - 2.5e-05 24.1 8.8 0.00012 21.8 1.4 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ11906.1 - 6.1e-05 21.9 0.2 0.049 12.3 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 OAJ11906.1 - 0.00019 21.4 5.0 0.0064 16.5 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAJ11906.1 - 0.0013 19.2 0.0 0.41 11.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAJ11906.1 - 0.0015 18.6 0.1 2.1 8.4 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAJ11906.1 - 0.0022 17.9 0.3 0.004 17.1 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAJ11906.1 - 0.0026 17.0 2.7 0.12 11.6 0.4 2.5 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 OAJ11906.1 - 0.019 14.3 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAJ11906.1 - 0.051 12.9 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OAJ11906.1 - 0.055 12.6 2.5 3.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ11906.1 - 0.082 12.1 1.4 0.83 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 OAJ11906.1 - 0.11 11.5 7.2 0.067 12.3 0.4 2.4 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OAJ11906.1 - 0.14 11.5 0.4 15 4.9 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAJ11906.1 - 0.24 11.0 0.5 0.53 9.8 0.5 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LRR_8 PF13855.6 OAJ11907.1 - 3.8e-16 58.6 20.1 1.7e-09 37.3 11.1 4.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAJ11907.1 - 3.5e-11 43.1 22.3 1.8e-05 25.0 4.0 5.4 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) Torus PF16131.5 OAJ11907.1 - 2.4e-08 34.6 5.3 5.5e-05 23.8 0.6 2.8 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 OAJ11907.1 - 5.8e-07 29.3 7.0 0.00088 19.1 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAJ11907.1 - 1.6e-06 27.7 8.0 0.0001 22.0 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ11907.1 - 9.8e-05 22.3 16.9 0.01 15.8 3.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ11907.1 - 0.00015 21.9 0.5 0.0003 21.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger containing family LRR_1 PF00560.33 OAJ11907.1 - 0.0016 18.7 11.9 55 4.9 0.0 7.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 OAJ11907.1 - 0.023 14.7 19.8 14 6.0 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich repeat NDC10_II PF16787.5 OAJ11918.1 - 2.7e-48 164.7 0.0 4.5e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_29 PF13551.6 OAJ11918.1 - 0.061 13.3 0.8 3.9 7.6 0.0 3.6 4 0 0 4 4 4 0 Winged helix-turn helix DASH_Hsk3 PF08227.11 OAJ11918.1 - 0.064 13.6 0.1 0.2 12.1 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Retrotran_gag_2 PF14223.6 OAJ11920.1 - 2.2e-14 53.3 0.0 3.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ11920.1 - 3.2e-06 26.7 0.1 5.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.6 OAJ11920.1 - 4.7e-05 23.2 1.0 8.1e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_3 PF14244.6 OAJ11920.1 - 0.03 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ11920.1 - 0.034 14.2 4.5 0.077 13.1 4.5 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 OAJ11921.1 - 5e-62 209.7 0.0 6.5e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PMT PF02366.18 OAJ11922.1 - 1e-08 35.1 3.1 0.0018 17.9 0.9 2.3 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Ycf9 PF01737.17 OAJ11922.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.1 2 1 0 2 2 2 0 YCF9 RNA_pol_Rpb4 PF03874.16 OAJ11929.1 - 1e-10 42.0 0.2 1.6e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Urease_linker PF18473.1 OAJ11929.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain BRCT_2 PF16589.5 OAJ11930.1 - 3.9e-09 36.8 0.0 7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAJ11930.1 - 7.4e-08 32.7 0.3 1.1e-06 28.9 0.1 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAJ11930.1 - 8.9e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 OAJ11930.1 - 0.0011 18.9 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain Endonuc_Holl PF10107.9 OAJ11930.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase adh_short PF00106.25 OAJ11931.1 - 2.9e-19 69.3 0.0 1.1e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11931.1 - 9.7e-12 44.9 0.0 2.8e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ11931.1 - 3.8e-08 33.5 0.1 7.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ11931.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF5339 PF17274.2 OAJ11932.1 - 2.9 8.8 5.7 0.79 10.6 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Na_Ca_ex PF01699.24 OAJ11933.1 - 8.9e-41 139.3 39.6 1e-20 74.2 13.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PseudoU_synth_1 PF01416.20 OAJ11942.1 - 2.6e-13 50.3 0.0 9.5e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase FAM176 PF14851.6 OAJ11942.1 - 0.29 10.8 1.9 0.59 9.8 1.9 1.4 1 0 0 1 1 1 0 FAM176 family GST_N_3 PF13417.6 OAJ11943.1 - 3.1e-05 24.3 0.0 9.7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ11943.1 - 0.076 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box PF00646.33 OAJ11944.1 - 0.096 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAJ11945.1 - 0.64 10.0 3.0 2.1 8.3 0.8 2.6 2 0 0 2 2 2 0 F-box-like CPSase_L_D2 PF02786.17 OAJ11946.1 - 3e-49 167.4 0.0 4.7e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.22 OAJ11946.1 - 2.5e-45 155.0 0.1 1e-40 139.8 0.0 2.2 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_N PF00289.22 OAJ11946.1 - 8.8e-25 87.4 0.0 1e-23 84.0 0.0 2.8 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ11946.1 - 2.4e-20 72.6 0.0 5.6e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ11946.1 - 8.1e-17 60.8 0.1 1.7e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ11946.1 - 1.4e-07 31.2 0.3 0.0049 16.7 0.7 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 OAJ11946.1 - 0.0014 19.3 0.4 1.3 9.7 0.0 3.1 3 0 0 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.6 OAJ11946.1 - 0.0036 17.2 0.1 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 OAJ11946.1 - 0.16 11.9 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) RVT_1 PF00078.27 OAJ11956.1 - 6.2e-19 68.4 0.0 3.1e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.9 OAJ11958.1 - 3e-07 30.8 0.0 7.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ11958.1 - 0.018 14.7 0.9 0.018 14.7 0.9 2.5 2 0 0 2 2 2 0 SWIM zinc finger F-box-like PF12937.7 OAJ11967.1 - 0.00065 19.6 0.1 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like Peptidase_M16 PF00675.20 OAJ11968.1 - 1.8e-39 135.1 0.0 3.3e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ11968.1 - 3.7e-38 131.4 0.0 6.7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2607 PF10795.9 OAJ11968.1 - 0.028 14.6 0.5 0.066 13.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) PXA PF02194.15 OAJ11968.1 - 0.13 12.2 1.4 19 5.2 0.1 3.2 3 0 0 3 3 3 0 PXA domain GPAT_N PF14829.6 OAJ11968.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal PH_4 PF15404.6 OAJ11971.1 - 4.2e-28 98.4 0.0 1.9e-27 96.3 0.0 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OAJ11971.1 - 0.32 11.5 2.1 16 6.0 0.0 3.9 5 0 0 5 5 5 0 PH domain 2OG-FeII_Oxy_2 PF13532.6 OAJ11983.1 - 1.3e-13 51.6 0.0 8.2e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Serglycin PF04360.12 OAJ11983.1 - 7.3 6.5 6.6 3.4 7.6 4.1 1.7 2 0 0 2 2 2 0 Serglycin zf-CCHC PF00098.23 OAJ11984.1 - 5.9 7.1 10.3 3.5 7.9 5.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Drf_GBD PF06371.13 OAJ11985.1 - 2.4e-13 50.1 0.0 4.4e-12 45.9 0.0 2.4 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Connexin PF00029.19 OAJ11985.1 - 0.23 11.2 2.1 0.4 10.4 2.1 1.3 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 OAJ11985.1 - 4.1 6.9 11.2 6.2 6.4 11.2 1.2 1 0 0 1 1 1 0 Spt20 family KCH PF16944.5 OAJ11986.1 - 5.6e-82 275.3 14.5 7.2e-82 274.9 14.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel DBR1 PF05011.13 OAJ11987.1 - 8.6e-24 84.5 0.0 1.5e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OAJ11987.1 - 2.3e-06 28.3 0.2 4.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4210 PF13915.6 OAJ11987.1 - 0.026 15.1 0.1 0.074 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) ATP-synt_DE_N PF02823.16 OAJ11988.1 - 5.2e-16 58.3 0.0 7.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Thg1 PF04446.12 OAJ11997.1 - 7.1e-49 165.0 0.0 1.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OAJ11997.1 - 8.1e-44 148.7 0.0 1.4e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain CPSF73-100_C PF11718.8 OAJ11999.1 - 6.4e-55 186.0 2.4 6.4e-55 186.0 2.4 2.5 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAJ11999.1 - 1.1e-29 102.9 0.0 2.5e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OAJ11999.1 - 1.1e-18 67.3 0.0 2.2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OAJ11999.1 - 7.6e-18 65.2 0.8 7.6e-18 65.2 0.8 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OAJ11999.1 - 5.4e-16 58.3 0.2 1.1e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OAJ11999.1 - 6.8e-08 32.3 0.9 6.2e-07 29.1 0.5 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAJ11999.1 - 6.8e-07 29.3 0.1 2.9e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain cNMP_binding PF00027.29 OAJ12000.1 - 1.6e-25 89.0 0.0 6.7e-14 51.7 0.0 5.5 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 OAJ12000.1 - 6.8e-18 65.6 4.5 1.6e-11 44.8 1.2 3.2 3 0 0 3 3 3 2 Patatin-like phospholipase RVT_1 PF00078.27 OAJ12010.1 - 0.0019 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ12010.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ12010.1 - 0.064 12.8 4.1 0.17 11.4 4.1 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 OAJ12011.1 - 8.3e-25 87.6 0.0 1.4e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12011.1 - 4.9e-11 42.4 0.0 9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Nipped-B_C PF12830.7 OAJ12023.1 - 5.3e-42 143.9 0.1 8.5e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus MFS_1 PF07690.16 OAJ12023.1 - 5e-26 91.5 17.1 7.7e-26 90.8 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MCM PF00493.23 OAJ12025.1 - 9.7e-98 325.7 0.1 1.4e-97 325.2 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ12025.1 - 9.8e-33 112.7 0.0 1.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ12025.1 - 2.1e-24 85.7 0.9 5.5e-24 84.4 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ12025.1 - 6.1e-16 58.9 0.0 1.7e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ12025.1 - 1.3e-07 31.3 0.0 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ12025.1 - 0.0028 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ12025.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ12025.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) EVE PF01878.18 OAJ12026.1 - 4.1e-35 120.9 0.0 1.2e-34 119.4 0.0 1.8 1 1 0 1 1 1 1 EVE domain Asp PF00026.23 OAJ12027.1 - 3.6e-114 381.4 0.2 4.3e-114 381.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ12027.1 - 3.9e-16 59.8 0.8 8.6e-14 52.2 0.8 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ12027.1 - 2.1e-05 24.4 0.0 0.0005 19.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAJ12027.1 - 0.00042 20.9 0.0 0.36 11.5 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ12027.1 - 0.0038 17.7 0.0 2.2 8.9 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF3564 PF12087.8 OAJ12027.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) BDHCT_assoc PF16204.5 OAJ12027.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein COX17 PF05051.13 OAJ12040.1 - 1.9e-20 73.0 5.0 2.4e-20 72.6 5.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DHHC PF01529.20 OAJ12043.1 - 1.1e-38 132.3 3.2 1.1e-38 132.3 3.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2569 PF10754.9 OAJ12043.1 - 0.032 14.7 4.6 2.4 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) RVT_1 PF00078.27 OAJ12057.1 - 0.00024 20.7 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ12057.1 - 0.082 12.7 0.2 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Acyl-CoA_dh_1 PF00441.24 OAJ12058.1 - 4.7e-48 163.2 5.6 4.7e-48 163.2 5.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ12058.1 - 3.3e-28 97.7 0.2 9.2e-28 96.3 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAJ12058.1 - 7.5e-25 87.8 0.2 7.5e-25 87.8 0.2 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ12058.1 - 5.3e-19 68.8 6.0 5.3e-19 68.8 6.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAJ12058.1 - 2.5e-05 24.1 0.1 0.00011 22.0 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TPR_1 PF00515.28 OAJ12070.1 - 2.5e-57 188.5 13.9 4.1e-07 29.5 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ12070.1 - 4.4e-51 166.9 13.6 5.2e-06 26.2 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ12070.1 - 7.7e-39 128.7 9.4 9.6e-05 22.3 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ12070.1 - 7.9e-29 99.1 22.7 6.9e-07 28.8 0.1 9.3 5 3 5 10 10 10 7 TPR repeat TPR_16 PF13432.6 OAJ12070.1 - 2.5e-28 98.4 12.1 2e-06 28.3 0.0 7.7 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ12070.1 - 6.7e-28 95.0 15.4 0.00062 20.0 0.3 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ12070.1 - 3.9e-27 92.6 10.2 0.002 18.8 0.0 9.5 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ12070.1 - 5e-27 94.2 8.9 4.4e-06 27.1 0.3 6.5 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ12070.1 - 5.7e-25 85.5 6.5 0.028 14.4 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ12070.1 - 5.9e-23 80.9 11.9 8.3e-05 22.8 0.1 7.1 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ12070.1 - 6.1e-20 70.5 10.5 0.011 16.3 0.0 9.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ12070.1 - 6.6e-18 64.6 10.0 0.0035 17.4 0.2 6.6 1 1 3 6 6 6 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ12070.1 - 2.2e-14 53.4 6.6 1.3e-07 31.7 0.7 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAJ12070.1 - 1.2e-06 28.0 9.1 0.036 13.3 0.6 5.2 1 1 4 5 5 5 2 Tetratricopeptide repeat DUF4919 PF16266.5 OAJ12070.1 - 5.1e-05 23.3 0.8 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) BTAD PF03704.17 OAJ12070.1 - 0.00071 20.0 5.8 0.23 11.9 0.6 3.9 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 OAJ12070.1 - 0.00078 19.2 18.3 0.54 10.2 0.2 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TOM20_plant PF06552.12 OAJ12070.1 - 0.021 14.6 0.5 7.6 6.2 0.0 3.5 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.10 OAJ12070.1 - 0.041 12.9 1.1 6.4 5.7 0.2 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 OAJ12070.1 - 0.049 14.0 0.0 0.049 14.0 0.0 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat DSPc PF00782.20 OAJ12086.1 - 3.1e-27 95.0 0.0 7.7e-21 74.3 0.0 2.9 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ12086.1 - 0.0027 17.3 0.0 0.0074 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Abhydrolase_2 PF02230.16 OAJ12099.1 - 0.025 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HAP1_N PF04849.13 OAJ12100.1 - 0.011 14.9 18.4 0.05 12.8 14.4 3.0 2 1 0 2 2 2 0 HAP1 N-terminal conserved region zf-C4H2 PF10146.9 OAJ12100.1 - 0.23 11.8 2.6 0.84 9.9 2.6 2.1 1 0 0 1 1 1 0 Zinc finger-containing protein ABC_tran_CTD PF16326.5 OAJ12100.1 - 0.77 10.0 16.4 0.16 12.3 10.2 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain PRODH PF18327.1 OAJ12100.1 - 0.79 10.0 6.9 4.6 7.5 0.3 2.9 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain Ceramidase_alk PF04734.13 OAJ12103.1 - 0.00093 18.0 0.1 0.0014 17.3 0.1 1.2 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Uds1 PF15456.6 OAJ12124.1 - 0.031 14.5 1.0 0.073 13.2 1.0 1.6 1 0 0 1 1 1 0 Up-regulated During Septation eIF-3c_N PF05470.12 OAJ12124.1 - 0.064 11.6 0.3 0.088 11.1 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Seryl_tRNA_N PF02403.22 OAJ12124.1 - 0.38 11.0 4.0 1 9.6 1.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 OAJ12124.1 - 0.57 9.5 8.3 11 5.3 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PCRF PF03462.18 OAJ12124.1 - 0.61 9.9 2.0 0.74 9.6 0.3 1.9 2 0 0 2 2 2 0 PCRF domain LMP PF04778.12 OAJ12124.1 - 1.1 9.2 6.8 0.23 11.3 2.0 2.0 2 0 0 2 2 2 0 LMP repeated region DUF3292 PF11696.8 OAJ12125.1 - 1.2e-06 27.2 0.4 1.2e-06 27.2 0.4 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) PRT_C PF08372.10 OAJ12125.1 - 0.0034 17.1 1.9 0.0079 16.0 0.6 2.0 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 OAJ12125.1 - 0.083 12.8 3.8 0.24 11.4 1.5 2.2 2 0 0 2 2 2 0 Reticulon ThiF PF00899.21 OAJ12126.1 - 4e-64 216.3 0.0 5.5e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAJ12126.1 - 1.5e-25 89.1 0.0 2.5e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAJ12126.1 - 0.0029 17.7 0.2 0.0067 16.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAJ12126.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAJ12126.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 OAJ12126.1 - 0.16 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 OAJ12126.1 - 0.27 11.1 0.3 15 5.4 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Ecm33 PF12454.8 OAJ12126.1 - 0.27 11.4 1.9 0.51 10.5 1.9 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_8 PF13450.6 OAJ12128.1 - 5.3e-09 36.2 0.1 1.1e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAJ12128.1 - 2.7e-08 33.6 0.0 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAJ12128.1 - 0.00049 19.4 0.1 0.0071 15.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ12128.1 - 0.02 14.5 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ12128.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 OAJ12128.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ12128.1 - 0.044 13.0 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ12128.1 - 0.047 12.9 0.1 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAJ12128.1 - 0.052 12.2 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OAJ12128.1 - 0.11 11.6 0.2 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAJ12128.1 - 0.43 10.6 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 1 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 OAJ12137.1 - 0.0003 19.9 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ12137.1 - 0.0057 16.8 14.8 0.0091 16.1 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clat_adaptor_s PF01217.20 OAJ12138.1 - 1.4e-43 148.2 0.3 5e-34 117.3 0.3 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Thr_synth_N PF14821.6 OAJ12139.1 - 2e-25 88.8 0.0 7.3e-25 87.0 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 OAJ12139.1 - 2.2e-19 70.0 0.0 1.3e-18 67.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CC2-LZ PF16516.5 OAJ12139.1 - 0.055 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CAF1C_H4-bd PF12265.8 OAJ12140.1 - 2.5e-28 98.1 0.1 5.9e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAJ12140.1 - 4.2e-25 87.5 10.3 0.00014 22.6 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12140.1 - 2.2e-06 27.9 1.1 0.019 15.3 0.1 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S7e PF01251.18 OAJ12141.1 - 5.3e-81 270.8 0.1 7.8e-81 270.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S7e Rad51 PF08423.11 OAJ12142.1 - 3.5e-128 426.2 0.1 4.2e-128 426.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAJ12142.1 - 7.6e-12 45.2 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 OAJ12142.1 - 5.8e-10 39.1 0.1 7.9e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OAJ12142.1 - 3.3e-07 29.9 0.1 6.4e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OAJ12142.1 - 6.7e-06 26.6 0.2 1.7e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 OAJ12142.1 - 0.0032 16.8 0.1 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 OAJ12142.1 - 0.0042 16.3 1.0 0.034 13.3 0.6 2.0 1 1 1 2 2 2 1 PAXNEB protein HHH PF00633.23 OAJ12142.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PAT1 PF09770.9 OAJ12150.1 - 0.0023 16.3 41.2 0.0025 16.2 41.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 OAJ12150.1 - 0.19 11.3 18.2 0.29 10.7 18.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 OAJ12150.1 - 2.6 7.8 25.6 4 7.2 25.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIFIN PF02009.16 OAJ12150.1 - 6 6.7 16.7 8 6.3 16.7 1.1 1 0 0 1 1 1 0 Rifin MARVEL PF01284.23 OAJ12151.1 - 0.22 11.6 16.7 0.78 9.8 16.1 2.2 1 1 0 1 1 1 0 Membrane-associating domain HSF_DNA-bind PF00447.17 OAJ12152.1 - 2e-28 98.8 0.4 3.1e-28 98.2 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding CENP-B_dimeris PF09026.10 OAJ12152.1 - 1.6 9.2 9.8 3.4 8.1 9.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ12152.1 - 7.7 5.7 6.8 12 5.1 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Alpha-amylase_C PF02806.18 OAJ12153.1 - 6.7e-28 97.0 0.1 1.7e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OAJ12153.1 - 1.4e-16 61.0 0.0 5.9e-12 45.8 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 OAJ12153.1 - 4.2e-15 55.9 0.0 1.5e-14 54.1 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Aminotran_1_2 PF00155.21 OAJ12153.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II AA_kinase PF00696.28 OAJ12167.1 - 1.9e-36 125.9 0.0 5e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.25 OAJ12167.1 - 3.5e-07 29.9 0.1 0.015 15.0 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OAJ12167.1 - 7.9e-06 25.6 0.2 7.9e-06 25.6 0.2 2.1 2 0 0 2 2 2 1 ACT domain PPR_2 PF13041.6 OAJ12168.1 - 1.9e-30 104.8 5.7 5e-11 42.6 0.2 8.4 7 1 3 10 10 10 5 PPR repeat family PPR PF01535.20 OAJ12168.1 - 1.9e-26 90.4 7.0 2.7e-06 27.3 0.1 11.4 12 0 0 12 12 12 4 PPR repeat PPR_3 PF13812.6 OAJ12168.1 - 2.4e-15 56.3 0.2 9.9e-06 25.6 0.1 5.5 4 1 2 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 OAJ12168.1 - 2e-14 53.4 6.6 5e-12 45.6 1.5 3.8 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAJ12168.1 - 3.3e-10 39.5 5.5 0.0011 18.7 0.0 6.2 8 0 0 8 8 8 2 PPR repeat TPR_7 PF13176.6 OAJ12168.1 - 0.0011 18.8 0.1 7.6 6.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DNA_Packaging PF11053.8 OAJ12168.1 - 0.025 14.4 0.1 0.09 12.6 0.1 1.9 1 0 0 1 1 1 0 Terminase DNA packaging enzyme TPR_8 PF13181.6 OAJ12168.1 - 0.13 12.6 4.1 2.5 8.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ12168.1 - 0.18 12.4 14.6 18 5.9 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 OAJ12169.1 - 3.1e-82 276.5 0.0 4.2e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ArgJ PF01960.18 OAJ12170.1 - 4.5e-131 437.0 0.0 6.6e-131 436.5 0.0 1.2 1 0 0 1 1 1 1 ArgJ family ABM PF03992.16 OAJ12171.1 - 0.29 11.3 3.3 0.14 12.3 0.3 2.1 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase CopC PF04234.12 OAJ12172.1 - 0.055 14.5 0.1 0.055 14.5 0.1 1.6 2 0 0 2 2 2 0 CopC domain FLYWCH_u PF16662.5 OAJ12172.1 - 0.79 9.8 4.4 0.5 10.5 0.7 2.0 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 DEAD PF00270.29 OAJ12192.1 - 6.9e-05 22.7 0.0 8.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_C107 PF17222.3 OAJ12192.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 1 0 1 1 1 0 Viral cysteine endopeptidase C107 Myb_DNA-bind_4 PF13837.6 OAJ12193.1 - 0.00027 21.3 0.3 0.00078 19.8 0.3 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain ThiD2 PF17792.1 OAJ12193.1 - 2 8.9 9.3 1.2 9.6 5.4 2.3 2 0 0 2 2 2 0 ThiD2 family DUF2058 PF09831.9 OAJ12193.1 - 5.2 7.2 9.6 4.1 7.5 7.7 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DEAD PF00270.29 OAJ12205.1 - 4.3e-32 111.3 0.0 8.3e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ12205.1 - 4.3e-29 101.1 0.0 1.3e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ12205.1 - 0.00063 19.8 0.0 0.00063 19.8 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Utp14 PF04615.13 OAJ12205.1 - 0.00086 18.0 26.6 0.0014 17.4 26.6 1.2 1 0 0 1 1 1 1 Utp14 protein Cwf_Cwc_15 PF04889.12 OAJ12205.1 - 0.0087 15.8 30.5 0.0087 15.8 30.5 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DnaI_N PF07319.11 OAJ12205.1 - 0.015 16.0 0.4 0.99 10.1 0.0 2.7 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Apt1 PF10351.9 OAJ12205.1 - 2.2 7.0 17.1 0.17 10.7 11.1 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain BUD22 PF09073.10 OAJ12205.1 - 8.3 5.6 44.7 16 4.7 44.7 1.4 1 0 0 1 1 1 0 BUD22 LIM PF00412.22 OAJ12206.1 - 3.1e-14 53.0 14.1 0.0002 21.5 0.0 5.5 6 0 0 6 6 6 4 LIM domain RhoGAP PF00620.27 OAJ12207.1 - 5.8e-45 152.8 0.0 1e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 OAJ12207.1 - 5.6e-17 61.8 1.0 1.5e-16 60.4 0.3 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PDEase_II PF02112.15 OAJ12208.1 - 2.9e-38 131.8 0.0 9.4e-20 71.0 0.0 3.5 4 0 0 4 4 4 2 cAMP phosphodiesterases class-II GARS_A PF01071.19 OAJ12218.1 - 3.3e-67 226.1 0.0 4.8e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 OAJ12218.1 - 1.1e-29 103.0 0.1 4.4e-29 101.1 0.1 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 OAJ12218.1 - 1.4e-27 96.8 0.0 3.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 OAJ12218.1 - 1.1e-26 93.0 0.4 2.5e-26 91.8 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OAJ12218.1 - 4.5e-13 49.7 1.1 2.4e-12 47.3 1.3 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Shikimate_DH PF01488.20 OAJ12218.1 - 0.15 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LtrA PF06772.11 OAJ12219.1 - 9.5e-35 120.4 23.8 1.3e-34 120.0 23.8 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4079 PF13301.6 OAJ12219.1 - 1.4 9.1 5.7 3.8 7.7 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) WD40 PF00400.32 OAJ12220.1 - 1.6e-39 133.2 20.1 7.6e-07 29.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12220.1 - 1.5e-13 50.8 0.2 0.00078 19.7 0.1 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAJ12220.1 - 0.022 14.1 0.0 0.18 11.1 0.0 2.0 2 1 1 3 3 3 0 WD40-like domain 4HBT_2 PF13279.6 OAJ12221.1 - 1.5e-15 57.7 0.0 2.3e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAJ12221.1 - 0.00018 20.9 0.1 0.00083 18.7 0.1 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.22 OAJ12221.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 1 0 1 1 1 0 Thioesterase superfamily adh_short PF00106.25 OAJ12222.1 - 1.5e-28 99.6 0.0 2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ12222.1 - 1.3e-18 67.4 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ12222.1 - 2.1e-05 24.5 0.5 8e-05 22.6 0.5 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ12222.1 - 0.0018 17.8 0.0 0.0044 16.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CAF1C_H4-bd PF12265.8 OAJ12223.1 - 3.5e-15 56.0 0.0 1.3e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAJ12223.1 - 1.6e-13 50.9 5.5 1.9e-06 28.5 0.2 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Med21 PF11221.8 OAJ12234.1 - 1.8e-21 76.9 2.0 2.3e-21 76.5 2.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex SHD1 PF03983.12 OAJ12235.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Sugar_tr PF00083.24 OAJ12237.1 - 1.3e-89 301.1 22.7 1.6e-89 300.8 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ12237.1 - 1.6e-13 50.4 42.1 9.2e-12 44.5 15.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DHHA2 PF02833.14 OAJ12238.1 - 1.5e-18 67.3 0.1 3.5e-18 66.2 0.1 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 OAJ12238.1 - 1.9e-10 40.8 0.0 1.5e-09 38.0 0.0 2.1 1 1 1 2 2 2 1 DHH family RRS1 PF04939.12 OAJ12247.1 - 2.3e-52 177.1 0.7 3.4e-52 176.6 0.7 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Complex1_51K PF01512.17 OAJ12248.1 - 2.7e-48 163.7 0.0 4.5e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAJ12248.1 - 1.4e-31 108.4 0.2 2.8e-31 107.4 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAJ12248.1 - 3.7e-08 33.1 0.0 8.7e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 OAJ12248.1 - 5.2 7.2 6.1 0.38 10.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Palm_thioest PF02089.15 OAJ12249.1 - 0.00022 21.1 0.0 0.00039 20.4 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 OAJ12249.1 - 0.00058 19.4 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAJ12249.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 OAJ12249.1 - 0.0044 16.3 0.0 0.0054 15.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 OAJ12249.1 - 0.0061 17.2 0.1 0.0073 16.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ12249.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 OAJ12249.1 - 0.087 12.1 0.0 0.16 11.3 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 OAJ12249.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 OAJ12249.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_1_2 PF00155.21 OAJ12250.1 - 3.6e-89 299.5 0.0 4.1e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 OAJ12251.1 - 2.6e-69 234.1 0.0 3.4e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ12251.1 - 0.00018 20.6 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ12251.1 - 0.00057 18.5 0.0 0.0021 16.7 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_S24 PF00717.23 OAJ12252.1 - 2.1e-09 37.2 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_C14 PF00656.22 OAJ12253.1 - 6.3e-60 203.2 0.0 7.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.25 OAJ12267.1 - 9e-39 133.4 0.0 1.3e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12267.1 - 4.3e-25 88.5 0.0 6.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ12267.1 - 0.00084 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ12267.1 - 0.024 14.0 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PS_Dcarbxylase PF02666.15 OAJ12268.1 - 3.6e-42 144.2 0.0 4.8e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Cutinase PF01083.22 OAJ12269.1 - 2e-23 83.3 0.0 2.3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase adh_short_C2 PF13561.6 OAJ12270.1 - 1.5e-46 158.9 1.5 1.5e-24 86.9 0.6 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ12270.1 - 7.4e-40 136.5 4.1 8.5e-32 110.2 1.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAJ12270.1 - 4.9e-17 62.4 0.4 2e-16 60.4 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAJ12270.1 - 0.003 17.0 0.1 0.0061 16.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ12270.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OAJ12270.1 - 0.03 14.2 2.7 0.14 12.0 1.3 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ12270.1 - 0.25 12.0 2.3 49 4.6 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent CDC45 PF02724.14 OAJ12271.1 - 0.036 12.4 0.1 0.049 11.9 0.1 1.3 1 1 0 1 1 1 0 CDC45-like protein Cadherin_5 PF17892.1 OAJ12271.1 - 0.13 12.2 0.2 0.8 9.7 0.0 2.2 2 1 0 2 2 2 0 Cadherin-like domain Glyco_hydro_8 PF01270.17 OAJ12283.1 - 4.7e-16 58.5 0.2 1.1e-15 57.4 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 Peptidase_S29 PF02907.15 OAJ12283.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease MPP6 PF10175.9 OAJ12285.1 - 0.0085 16.6 11.6 1.8 9.1 11.6 2.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 DEC-1_N PF04625.13 OAJ12285.1 - 0.32 10.0 4.8 0.51 9.3 4.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Hamartin PF04388.12 OAJ12285.1 - 1.2 7.8 5.7 1.4 7.5 5.7 1.0 1 0 0 1 1 1 0 Hamartin protein API5 PF05918.11 OAJ12285.1 - 6.5 5.4 5.1 10 4.8 5.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PBP1_TM PF14812.6 OAJ12285.1 - 9.6 6.7 18.5 5.3 7.5 3.3 2.4 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spo7 PF03907.13 OAJ12286.1 - 3.2e-17 62.8 0.3 6.9e-08 32.2 0.1 2.3 2 0 0 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.9 OAJ12286.1 - 0.071 13.5 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 188 MARVEL PF01284.23 OAJ12286.1 - 0.72 9.9 8.1 0.23 11.5 0.8 2.6 3 0 0 3 3 3 0 Membrane-associating domain GTP_EFTU PF00009.27 OAJ12287.1 - 4.2e-42 143.9 0.0 6.9e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAJ12287.1 - 2.5e-33 115.3 7.1 4.1e-33 114.6 7.1 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAJ12287.1 - 7.8e-24 83.8 0.0 2e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAJ12287.1 - 2.4e-20 72.3 0.0 6.1e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ12287.1 - 3.5e-07 30.5 0.1 7.4e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ12287.1 - 1.9e-06 27.9 0.1 3.6e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 OAJ12287.1 - 0.00015 21.8 0.1 0.00031 20.8 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 OAJ12287.1 - 0.00089 18.9 0.0 0.0026 17.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAJ12287.1 - 0.078 13.2 0.0 0.33 11.2 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ12287.1 - 0.11 11.9 0.2 0.34 10.3 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Serglycin PF04360.12 OAJ12288.1 - 0.061 13.3 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Serglycin PSK_trans_fac PF07704.11 OAJ12288.1 - 3.5 8.4 7.3 0.7 10.7 0.3 3.0 3 1 0 3 3 3 0 Rv0623-like transcription factor NOA36 PF06524.12 OAJ12305.1 - 0.77 9.0 3.3 0.8 9.0 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein hDGE_amylase PF14701.6 OAJ12306.1 - 1.5e-164 548.3 0.0 2e-164 547.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAJ12306.1 - 5.7e-111 371.1 0.0 7.6e-111 370.7 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OAJ12306.1 - 6.9e-85 284.7 0.0 1.1e-84 284.0 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAJ12306.1 - 9.5e-20 70.5 0.0 2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAJ12306.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Mucin PF01456.17 OAJ12306.1 - 8.7 6.3 16.6 19 5.3 16.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF92 PF01940.16 OAJ12308.1 - 6.8e-67 225.3 5.4 8.6e-67 225.0 5.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 GerA PF03323.13 OAJ12308.1 - 0.53 8.7 2.0 0.83 8.0 2.0 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Sulfate_transp PF00916.20 OAJ12309.1 - 8.9e-111 370.3 15.7 1.2e-110 369.9 15.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAJ12309.1 - 4.6e-10 39.1 0.0 8.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAJ12309.1 - 0.027 14.9 19.2 0.037 14.4 3.4 3.4 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF3648 PF12364.8 OAJ12325.1 - 0.094 12.9 0.1 0.6 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) YhfC PF10086.9 OAJ12325.1 - 0.14 11.5 4.5 0.12 11.8 0.8 2.1 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease MARVEL PF01284.23 OAJ12325.1 - 0.71 9.9 7.8 1.1 9.2 5.3 2.2 1 1 1 2 2 2 0 Membrane-associating domain CRPA PF05745.11 OAJ12326.1 - 0.3 11.1 1.5 0.53 10.3 1.5 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Thiolase_N PF00108.23 OAJ12337.1 - 1.7e-79 266.8 9.1 1.8e-79 266.8 5.3 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ12337.1 - 1.3e-43 147.5 0.5 2.9e-43 146.4 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ12337.1 - 0.0095 15.5 4.4 0.022 14.4 0.4 3.1 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain DUF903 PF06004.12 OAJ12337.1 - 0.087 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) ACP_syn_III_C PF08541.10 OAJ12337.1 - 0.091 12.9 0.1 0.31 11.2 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Reprolysin_5 PF13688.6 OAJ12338.1 - 9e-45 153.2 5.1 9e-45 153.2 5.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAJ12338.1 - 2.1e-43 148.5 2.1 5.4e-43 147.2 2.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAJ12338.1 - 1.2e-42 145.8 1.1 3.3e-42 144.5 1.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OAJ12338.1 - 2.1e-14 54.0 24.3 2.1e-14 54.0 24.3 4.0 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 OAJ12338.1 - 3.1e-11 43.9 0.0 7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OAJ12338.1 - 2.6e-08 34.0 4.1 8e-07 29.2 0.1 3.4 2 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 OAJ12338.1 - 1.1e-06 28.9 0.1 2.8e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 OAJ12338.1 - 0.01 16.3 10.8 0.01 16.3 10.8 4.1 2 1 1 3 3 3 0 ADAM cysteine-rich domain Histone PF00125.24 OAJ12339.1 - 1.1e-49 168.1 3.9 1.3e-49 167.9 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ12339.1 - 9e-05 22.8 0.1 0.00014 22.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OAJ12339.1 - 9.8e-05 23.0 0.8 0.0001 22.9 0.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OAJ12339.1 - 0.00035 20.7 0.2 0.00035 20.7 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ12339.1 - 0.002 18.4 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HisKA PF00512.25 OAJ12339.1 - 0.035 14.1 0.3 0.064 13.3 0.3 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Ran_BP1 PF00638.18 OAJ12340.1 - 7.6e-15 55.3 0.0 2.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain Syntaxin PF00804.25 OAJ12341.1 - 3.1e-26 92.3 8.6 3.1e-26 92.3 8.6 2.1 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 OAJ12341.1 - 7.5e-05 22.6 2.4 7.5e-05 22.6 2.4 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 OAJ12341.1 - 0.00017 21.9 4.4 0.00017 21.9 4.4 2.1 2 1 0 2 2 2 1 Syntaxin-like protein Muted PF14942.6 OAJ12341.1 - 0.0036 17.7 2.9 0.0036 17.7 2.9 2.2 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein Herpes_US9 PF06072.11 OAJ12341.1 - 0.081 12.8 2.2 0.18 11.7 2.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 GRP PF07172.11 OAJ12341.1 - 0.19 12.4 10.6 1.4 9.6 9.2 2.7 2 0 0 2 2 2 0 Glycine rich protein family DUF1657 PF07870.11 OAJ12341.1 - 0.2 11.5 2.4 0.73 9.8 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1657) DUF2721 PF11026.8 OAJ12341.1 - 0.43 10.5 2.9 12 5.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TPR_14 PF13428.6 OAJ12341.1 - 1.6 9.8 4.7 3 8.9 0.1 3.5 4 1 0 4 4 3 0 Tetratricopeptide repeat TcdA_TcdB PF12919.7 OAJ12341.1 - 1.6 7.9 10.0 0.55 9.5 4.5 2.1 1 1 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain TMPIT PF07851.13 OAJ12341.1 - 2.9 7.0 8.5 1.3 8.3 1.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein dCache_1 PF02743.18 OAJ12341.1 - 3 7.6 6.7 1.5 8.6 4.0 1.7 1 1 0 2 2 2 0 Cache domain Phage_Mu_Gam PF07352.12 OAJ12341.1 - 4.8 7.1 8.7 0.46 10.4 2.1 2.4 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF4715 PF15835.5 OAJ12341.1 - 5.3 7.1 7.8 0.43 10.6 1.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4715) FUSC PF04632.12 OAJ12341.1 - 8.7 4.7 15.2 0.17 10.4 5.2 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family CENP-T_C PF15511.6 OAJ12342.1 - 7.6e-08 32.5 0.1 9.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ12342.1 - 0.00021 21.4 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ12342.1 - 0.00047 20.5 0.0 0.00062 20.1 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAJ12342.1 - 0.00062 20.1 0.1 0.0007 20.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ12342.1 - 0.00091 19.5 0.1 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ12342.1 - 0.05 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Endonuclease_5 PF04493.14 OAJ12350.1 - 7.3e-48 162.9 0.0 1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 OAJ12350.1 - 0.048 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 E1-E2_ATPase PF00122.20 OAJ12351.1 - 1.4e-32 112.7 15.2 6.8e-28 97.4 1.1 3.8 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ12351.1 - 4e-31 108.1 1.6 4e-31 108.1 1.6 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ12351.1 - 7.8e-18 65.5 2.2 1.9e-13 51.2 0.1 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ12351.1 - 2.6e-16 59.0 0.1 9.5e-16 57.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ12351.1 - 8.9e-12 44.9 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ12351.1 - 0.044 13.5 0.1 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ACOX PF01756.19 OAJ12352.1 - 5.5e-44 149.9 0.0 9e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAJ12352.1 - 2.4e-19 69.3 0.0 4.9e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 OAJ12352.1 - 3.9e-11 43.6 0.0 1.2e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 OAJ12352.1 - 7.2e-10 39.3 0.8 3.6e-09 37.0 0.8 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AhpC-TSA PF00578.21 OAJ12353.1 - 4.5e-32 110.6 0.0 6.2e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ12353.1 - 6.9e-13 48.5 0.0 9.3e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAJ12353.1 - 1.2e-10 41.1 0.1 2.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin XPA_C PF05181.12 OAJ12354.1 - 4.6e-24 84.1 1.0 9.1e-24 83.2 1.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Stc1 PF12898.7 OAJ12354.1 - 0.15 12.6 5.1 3.4 8.3 0.8 2.5 2 0 0 2 2 2 0 Stc1 domain XPA_N PF01286.18 OAJ12354.1 - 0.84 9.7 8.1 0.24 11.5 1.4 2.3 2 0 0 2 2 2 0 XPA protein N-terminal DWNN PF08783.11 OAJ12365.1 - 3.9e-32 110.4 0.0 6.7e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAJ12365.1 - 1.6e-09 37.4 7.0 2.9e-09 36.6 7.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ12365.1 - 4.8e-06 26.4 1.7 9.4e-06 25.5 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ12365.1 - 0.0034 17.3 0.1 0.011 15.7 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 OAJ12365.1 - 0.0069 16.2 9.3 0.0069 16.2 9.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 OAJ12365.1 - 0.026 14.2 0.6 0.072 12.8 0.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_2 PF13639.6 OAJ12365.1 - 2.8 8.3 10.9 5.9 7.3 10.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ12365.1 - 5 7.1 19.5 0.13 12.1 12.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFIIF_alpha PF05793.12 OAJ12366.1 - 0.92 8.0 11.2 2.2 6.8 11.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CN_hydrolase PF00795.22 OAJ12367.1 - 1.8e-13 50.4 0.0 1.6e-07 30.9 0.0 3.7 3 1 1 4 4 4 3 Carbon-nitrogen hydrolase Flg_hook PF02120.16 OAJ12367.1 - 0.091 12.7 0.6 0.58 10.1 0.1 2.4 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Peptidase_S8 PF00082.22 OAJ12368.1 - 2e-39 135.6 2.7 3.6e-39 134.8 2.7 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ12368.1 - 2.3e-12 47.6 0.1 4.8e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAJ12368.1 - 0.00073 19.5 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.16 OAJ12368.1 - 0.12 13.1 0.0 0.77 10.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I9 IBR PF01485.21 OAJ12382.1 - 0.00031 20.9 4.4 0.00031 20.9 4.4 3.9 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain vMSA PF00695.19 OAJ12382.1 - 2.6 7.0 7.4 5.8 5.9 7.4 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus TMEM214 PF10151.9 OAJ12382.1 - 4.5 5.6 5.5 7 5.0 5.5 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator COX5A PF02284.16 OAJ12383.1 - 1.7e-41 140.4 0.4 2.5e-41 139.9 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF3523 PF12037.8 OAJ12383.1 - 0.062 12.7 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Pilin_N PF07790.11 OAJ12383.1 - 0.22 12.5 1.7 0.43 11.5 1.7 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Mt_ATP-synt_B PF05405.14 OAJ12384.1 - 1.8e-46 157.8 7.2 2.2e-46 157.5 7.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.8 OAJ12384.1 - 0.00046 20.2 0.2 0.00079 19.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF1539 PF07560.11 OAJ12384.1 - 0.084 13.0 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Cauli_DNA-bind PF03310.13 OAJ12384.1 - 0.093 12.8 3.0 0.085 12.9 1.0 1.8 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein V_ATPase_I PF01496.19 OAJ12384.1 - 0.39 8.6 4.1 0.49 8.3 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RICTOR_N PF14664.6 OAJ12385.1 - 1e-62 212.3 0.0 5.3e-62 210.0 0.0 2.2 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 OAJ12385.1 - 1.9e-31 107.9 1.1 4e-29 100.5 0.5 4.0 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OAJ12385.1 - 1.4e-28 99.4 0.0 8.5e-28 96.9 0.0 2.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 OAJ12385.1 - 1e-27 96.2 0.3 6e-26 90.5 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAJ12385.1 - 3.6e-05 23.8 0.1 8.1e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 OAJ12385.1 - 0.24 11.8 0.7 1 9.8 0.2 2.5 2 0 0 2 2 2 0 HEAT repeat Coa1 PF08695.10 OAJ12386.1 - 7.2e-30 103.1 0.0 1e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_21 PF09976.9 OAJ12386.1 - 0.041 13.6 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain PAP_PilO PF06864.12 OAJ12386.1 - 0.087 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) TPR_1 PF00515.28 OAJ12404.1 - 4.4e-08 32.6 1.6 0.26 11.2 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ12404.1 - 8e-08 32.5 20.6 0.052 13.8 1.3 6.0 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ12404.1 - 6.7e-07 28.9 9.7 0.051 13.7 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ12404.1 - 0.0022 18.1 5.8 4.2 7.8 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ12404.1 - 0.0029 18.3 14.9 1.6 9.8 0.3 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ12404.1 - 0.061 13.4 5.5 42 4.5 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat HbrB PF08539.11 OAJ12404.1 - 0.089 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 HbrB-like Phage_term_smal PF05944.12 OAJ12404.1 - 0.12 12.3 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 Phage small terminase subunit ANAPC3 PF12895.7 OAJ12404.1 - 0.3 11.4 4.9 14 6.0 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAJ12404.1 - 0.33 11.5 11.4 11 6.6 0.2 6.0 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ12404.1 - 0.53 11.0 17.1 2.4 8.9 4.4 5.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ12404.1 - 4.9 7.2 14.4 14 5.7 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat MTP18 PF10558.9 OAJ12405.1 - 5.9e-61 205.4 1.2 1.2e-60 204.4 1.2 1.5 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) AhpC-TSA PF00578.21 OAJ12406.1 - 1.2e-24 86.6 0.0 1.9e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ12406.1 - 1.3e-09 38.0 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Redoxin RVT_2 PF07727.14 OAJ12407.1 - 9.4e-62 208.8 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 OAJ12407.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Phosphodiest PF01663.22 OAJ12419.1 - 0.00014 21.6 0.1 0.00025 20.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase zf-TFIIB PF13453.6 OAJ12419.1 - 0.0057 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor zinc-finger Tub_N PF16322.5 OAJ12419.1 - 9.4 6.6 12.6 16 5.8 1.8 2.7 3 0 0 3 3 3 0 Tubby N-terminal DDOST_48kD PF03345.14 OAJ12420.1 - 8.5e-73 245.5 0.0 3.4e-72 243.6 0.0 1.8 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta adh_short PF00106.25 OAJ12420.1 - 4.5e-05 23.0 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ12420.1 - 0.039 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase LSM PF01423.22 OAJ12421.1 - 3e-22 78.1 0.1 3.7e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAJ12421.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Zn_clus PF00172.18 OAJ12422.1 - 1.5e-08 34.6 10.4 2.2e-08 34.1 10.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.8 OAJ12423.1 - 1.1e-38 133.0 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Vault_2 PF17794.1 OAJ12423.1 - 7.4 7.0 5.2 8.6 6.8 0.0 3.2 4 1 0 4 4 4 0 Major Vault Protein repeat domain GTP_EFTU PF00009.27 OAJ12424.1 - 2e-56 190.6 0.4 3e-56 190.1 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ12424.1 - 1.7e-29 102.4 0.0 3.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ12424.1 - 2.3e-16 60.0 3.5 2.3e-16 60.0 3.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ12424.1 - 1.9e-05 24.7 0.1 4.3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ12424.1 - 0.006 16.5 0.2 0.019 14.9 0.1 1.7 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 OAJ12424.1 - 0.014 14.9 0.5 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAJ12424.1 - 0.057 13.2 0.7 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Myb_DNA-bind_3 PF12776.7 OAJ12439.1 - 3.3e-12 47.2 0.1 9e-12 45.8 0.1 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MULE PF10551.9 OAJ12440.1 - 2.2e-09 37.6 0.0 8.7e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 OAJ12440.1 - 0.014 15.0 0.8 0.036 13.7 0.8 1.7 1 0 0 1 1 1 0 SWIM zinc finger OxoDH_E1alpha_N PF12573.8 OAJ12453.1 - 0.089 12.6 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal zf-NOSIP PF15906.5 OAJ12454.1 - 7e-12 45.3 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 OAJ12454.1 - 2.1e-05 24.3 14.2 0.011 15.5 4.7 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ12454.1 - 3.4e-05 23.7 11.8 0.00016 21.5 1.6 2.9 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 OAJ12454.1 - 0.0001 22.5 14.6 0.028 14.7 3.9 3.2 3 0 0 3 3 3 2 Ring finger domain FYVE PF01363.21 OAJ12454.1 - 0.00026 21.1 6.0 0.00058 19.9 0.9 2.7 2 0 0 2 2 2 1 FYVE zinc finger Rtf2 PF04641.12 OAJ12454.1 - 0.00029 20.3 14.9 0.0013 18.2 0.2 3.0 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_UBOX PF13445.6 OAJ12454.1 - 0.0009 19.2 12.5 0.036 14.1 2.9 3.1 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ12454.1 - 0.00094 19.0 17.1 0.011 15.5 5.2 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ12454.1 - 0.022 14.6 21.6 1.6 8.7 6.0 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAJ12454.1 - 0.21 11.5 17.4 0.22 11.4 5.2 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ12454.1 - 0.67 10.2 18.1 0.12 12.6 3.7 3.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING TBP PF00352.21 OAJ12455.1 - 1.6e-67 223.5 0.2 1.7e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAJ12455.1 - 1.1e-05 25.4 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAJ12455.1 - 0.073 12.9 0.2 0.62 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) PEN-2 PF10251.9 OAJ12456.1 - 0.76 10.2 5.1 0.18 12.3 0.9 1.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Ysc84 PF04366.12 OAJ12457.1 - 4e-37 126.8 0.7 9.1e-37 125.7 0.7 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_9 PF14604.6 OAJ12457.1 - 3.8e-14 52.3 0.0 7.1e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ12457.1 - 9.7e-12 44.3 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ12457.1 - 2.5e-09 36.7 0.0 5.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.6 OAJ12470.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Asn_synthase PF00733.21 OAJ12471.1 - 2.4e-42 145.9 2.5 2.5e-32 112.9 0.1 2.8 1 1 1 2 2 2 2 Asparagine synthase S8_pro-domain PF16470.5 OAJ12472.1 - 0.014 16.1 0.1 0.022 15.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase S8 pro-domain Transposase_21 PF02992.14 OAJ12486.1 - 2.9e-05 23.4 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 KIF1B PF12423.8 OAJ12486.1 - 0.023 15.1 0.5 0.084 13.3 0.5 2.0 1 0 0 1 1 1 0 Kinesin protein 1B Pheromone PF08015.11 OAJ12487.1 - 3.8 8.6 12.7 6.6 7.9 6.5 3.3 3 0 0 3 3 3 0 Fungal mating-type pheromone Macoilin PF09726.9 OAJ12487.1 - 6.3 5.2 11.1 9.3 4.7 11.1 1.1 1 0 0 1 1 1 0 Macoilin family ELFV_dehydrog_N PF02812.18 OAJ12488.1 - 0.0022 17.9 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ICE2 PF08426.10 OAJ12488.1 - 0.016 14.4 0.0 0.079 12.1 0.0 1.9 2 0 0 2 2 2 0 ICE2 SDA1 PF05285.12 OAJ12488.1 - 0.093 12.1 6.5 0.14 11.6 6.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ12488.1 - 0.4 8.9 5.0 0.76 8.0 5.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 OAJ12488.1 - 0.78 9.6 6.7 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF913 PF06025.12 OAJ12488.1 - 3.6 6.5 5.8 33 3.3 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Peroxin-3 PF04882.12 OAJ12498.1 - 1.7e-13 50.4 0.0 3.6e-11 42.7 0.0 2.2 1 1 0 2 2 2 2 Peroxin-3 H_lectin PF09458.10 OAJ12500.1 - 1.6e-17 63.4 0.0 2.6e-08 33.9 0.0 2.9 2 0 0 2 2 2 2 H-type lectin domain DHR10 PF18595.1 OAJ12500.1 - 0.27 11.3 3.6 0.29 11.2 0.1 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain 2OG-FeII_Oxy_3 PF13640.6 OAJ12501.1 - 7.1e-05 23.6 0.0 0.00018 22.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Helitron_like_N PF14214.6 OAJ12513.1 - 5.2e-61 206.2 0.2 8.3e-61 205.5 0.2 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus F-box-like PF12937.7 OAJ12513.1 - 0.00041 20.2 0.7 0.0034 17.3 1.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ12513.1 - 0.038 13.9 0.1 0.31 11.0 0.1 2.5 2 0 0 2 2 2 0 F-box domain LRR_11 PF18831.1 OAJ12513.1 - 0.11 12.1 0.1 0.34 10.5 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat tRNA_anti-codon PF01336.25 OAJ12515.1 - 0.54 10.3 2.2 0.74 9.8 0.5 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain 3Beta_HSD PF01073.19 OAJ12523.1 - 1.8e-15 56.7 0.0 1.3e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ12523.1 - 8.4e-13 48.3 1.2 3.4e-12 46.4 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ12523.1 - 1.1e-10 41.8 0.0 1.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAJ12523.1 - 9.3e-08 31.9 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAJ12523.1 - 1.4e-07 30.9 0.0 5.3e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ12523.1 - 2.3e-07 30.5 0.5 5.3e-07 29.4 0.0 1.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAJ12523.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAJ12523.1 - 0.0034 16.9 0.6 0.0086 15.5 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_2 PF03446.15 OAJ12523.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 OAJ12523.1 - 0.013 15.5 0.3 0.23 11.4 0.3 2.3 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 OAJ12523.1 - 0.041 14.1 0.1 0.26 11.5 0.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF5131 PF07505.11 OAJ12523.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Ribosomal_S21 PF01165.20 OAJ12524.1 - 1.6e-10 40.5 5.1 3.1e-10 39.6 5.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Complex1_LYR_2 PF13233.6 OAJ12525.1 - 1.4e-14 54.6 0.0 6.6e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Complex1_LYR-like UFD1 PF03152.14 OAJ12526.1 - 1.6e-66 223.1 0.0 2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 OAJ12526.1 - 0.2 11.8 0.0 4.4 7.5 0.0 2.5 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain LRR_6 PF13516.6 OAJ12527.1 - 0.00021 21.1 2.9 1.6 9.0 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 OAJ12527.1 - 0.00028 21.2 2.3 1.5 9.4 0.0 5.5 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ12527.1 - 0.71 10.7 2.4 64 4.7 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat PPP4R2 PF09184.11 OAJ12527.1 - 0.78 9.3 5.8 1.6 8.3 5.8 1.4 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 OAJ12527.1 - 3.3 5.7 8.7 41 2.1 8.9 2.0 2 0 0 2 2 2 0 DNA polymerase phi DUF3245 PF11595.8 OAJ12527.1 - 5.2 7.5 13.3 25 5.3 13.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) UDPGT PF00201.18 OAJ12528.1 - 4.1e-08 32.5 0.0 1.2e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.6 OAJ12528.1 - 0.046 13.8 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like Put_Phosphatase PF06888.12 OAJ12529.1 - 3.3e-50 170.7 0.0 4e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 OAJ12529.1 - 6.3e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.6 OAJ12530.1 - 2.7e-47 161.3 0.9 3.7e-47 160.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ12530.1 - 5.6e-35 120.6 0.0 7.3e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ12530.1 - 5e-09 36.3 0.1 8.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain HEAT_EZ PF13513.6 OAJ12548.1 - 1.8e-16 60.2 0.4 8e-07 29.4 0.0 5.1 4 1 1 5 5 5 4 HEAT-like repeat HEAT PF02985.22 OAJ12548.1 - 6e-14 51.0 0.6 5.4e-05 23.1 0.1 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 OAJ12548.1 - 1.9e-09 37.8 2.2 0.0013 19.1 0.1 4.3 3 1 1 4 4 4 3 HEAT repeats MMS19_C PF12460.8 OAJ12548.1 - 1.2e-07 31.2 0.1 0.0015 17.7 0.0 3.2 2 2 1 3 3 3 2 RNAPII transcription regulator C-terminal UME PF08064.13 OAJ12548.1 - 7.6e-05 22.6 0.0 0.17 11.8 0.0 3.3 2 2 1 3 3 3 2 UME (NUC010) domain Cnd1 PF12717.7 OAJ12548.1 - 0.00073 19.6 1.1 0.09 12.8 0.0 3.5 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 E3_UbLigase_R4 PF13764.6 OAJ12548.1 - 0.024 12.8 0.1 0.031 12.4 0.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Cohesin_HEAT PF12765.7 OAJ12548.1 - 0.035 14.4 0.1 0.23 11.8 0.0 2.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 OAJ12548.1 - 0.045 14.3 0.1 14 6.4 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Rcd1 PF04078.13 OAJ12548.1 - 0.061 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like KDZ PF18758.1 OAJ12551.1 - 1.9e-42 145.4 0.4 3.2e-42 144.6 0.4 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Cytochrom_NNT PF03264.14 OAJ12552.1 - 0.037 13.7 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region zf-BED PF02892.15 OAJ12552.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger zf-C3HC4_3 PF13920.6 OAJ12554.1 - 2.8e-06 27.1 0.8 4e-06 26.6 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ12554.1 - 0.0064 16.3 1.6 0.014 15.2 1.5 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.14 OAJ12554.1 - 0.0081 15.8 0.3 0.011 15.4 0.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 OAJ12554.1 - 0.025 14.9 0.8 0.044 14.1 0.8 1.4 1 1 0 1 1 1 0 Ring finger domain FdhE PF04216.12 OAJ12554.1 - 0.036 13.9 0.4 0.046 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Prok-RING_4 PF14447.6 OAJ12554.1 - 0.067 13.1 1.6 3 7.8 1.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 OAJ12554.1 - 0.86 9.5 3.5 21 5.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) tRNA-synt_1 PF00133.22 OAJ12555.1 - 2.4e-05 22.8 0.0 2.6e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OAJ12555.1 - 0.02 14.4 0.0 0.023 14.2 0.0 1.0 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 PCI PF01399.27 OAJ12564.1 - 1.1e-05 25.9 0.0 2.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain Dppa2_A PF14049.6 OAJ12565.1 - 0.061 13.5 6.4 0.25 11.5 6.4 2.1 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates Dsh_C PF12316.8 OAJ12566.1 - 0.38 11.1 8.8 0.092 13.1 0.5 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Macoilin PF09726.9 OAJ12568.1 - 0.036 12.6 8.2 0.051 12.1 8.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF1754 PF08555.10 OAJ12568.1 - 0.31 11.9 21.4 0.21 12.4 11.6 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF2968 PF11180.8 OAJ12568.1 - 1.5 8.5 14.2 2.1 7.9 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Pox_Ag35 PF03286.14 OAJ12568.1 - 1.8 8.4 18.8 0.35 10.6 7.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 OAJ12568.1 - 2.8 7.2 9.8 0.33 10.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RNA_pol_3_Rpc31 PF11705.8 OAJ12568.1 - 9.6 6.4 24.0 0.76 10.0 13.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 HTH_Tnp_Tc5 PF03221.16 OAJ12569.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain CIAPIN1 PF05093.13 OAJ12577.1 - 3.8e-32 110.8 1.9 8.9e-32 109.6 1.9 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 OAJ12577.1 - 4.7e-08 33.3 0.0 7.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus RT_RNaseH_2 PF17919.1 OAJ12578.1 - 5.3e-32 109.8 0.0 1.2e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ12578.1 - 9.4e-28 96.6 0.0 2.5e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ12578.1 - 5.5e-20 71.8 0.0 9.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ12578.1 - 2.4e-14 53.5 0.1 1.1e-13 51.5 0.1 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ12578.1 - 2.1e-09 37.4 0.5 4.7e-09 36.2 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 OAJ12578.1 - 0.004 17.2 8.3 0.004 17.2 8.3 2.4 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 OAJ12578.1 - 0.018 14.8 0.0 0.064 13.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain PX PF00787.24 OAJ12590.1 - 1.6e-24 86.0 0.1 1.6e-24 86.0 0.1 1.8 2 0 0 2 2 2 1 PX domain eIF-3_zeta PF05091.12 OAJ12590.1 - 1.5 7.7 15.7 2.6 6.9 15.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 OAJ12590.1 - 4.5 7.0 11.8 6.5 6.5 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABC_trans_N PF14510.6 OAJ12591.1 - 1.5e-12 47.9 0.3 2.5e-12 47.2 0.3 1.4 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 OAJ12591.1 - 2.7e-08 34.4 0.1 1.5e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DnaB_C PF03796.15 OAJ12591.1 - 0.019 14.3 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Sds3 PF08598.11 OAJ12592.1 - 3.2e-09 37.1 9.5 3.2e-09 37.1 9.5 2.2 2 0 0 2 2 2 1 Sds3-like Presenilin PF01080.17 OAJ12592.1 - 0.016 14.0 12.2 0.45 9.2 12.5 2.2 2 0 0 2 2 2 0 Presenilin SUZ PF12752.7 OAJ12592.1 - 0.11 13.3 0.2 0.11 13.3 0.2 5.3 4 2 0 4 4 4 0 SUZ domain EPL1 PF10513.9 OAJ12592.1 - 2.8 8.3 16.1 0.059 13.8 8.5 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Baculo_PP31 PF05311.11 OAJ12592.1 - 5.4 6.4 23.0 0.036 13.6 1.7 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SPX PF03105.19 OAJ12593.1 - 0.02 14.8 1.3 0.029 14.3 1.3 1.2 1 0 0 1 1 1 0 SPX domain Peptidase_C12 PF01088.21 OAJ12594.1 - 1e-52 179.0 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Utp12 PF04003.12 OAJ12595.1 - 1.5e-18 67.1 0.6 3e-18 66.1 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family DnaJ PF00226.31 OAJ12596.1 - 5.9e-16 58.4 0.4 1.2e-15 57.3 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 OAJ12596.1 - 1e-15 57.6 0.0 1.5e-14 53.8 0.0 2.4 1 1 0 1 1 1 1 Sec63 Brl domain LIDHydrolase PF10230.9 OAJ12596.1 - 0.043 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Muted PF14942.6 OAJ12605.1 - 1 9.7 5.3 2 8.7 5.3 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SWIM PF04434.17 OAJ12606.1 - 1.2e-05 24.8 0.4 2.5e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF3844 PF12955.7 OAJ12607.1 - 4.4e-26 91.1 0.2 8.4e-26 90.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Internalin_N PF12354.8 OAJ12607.1 - 0.55 10.3 4.7 0.53 10.4 0.8 2.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal CoA_binding PF02629.19 OAJ12608.1 - 7.6e-29 100.3 1.7 4e-28 97.9 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAJ12608.1 - 1.2e-19 70.6 0.6 2.6e-19 69.5 0.6 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAJ12608.1 - 4e-09 36.4 0.1 8.9e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 OAJ12608.1 - 0.053 14.3 0.0 0.22 12.4 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Prefoldin_2 PF01920.20 OAJ12609.1 - 3.3e-23 81.7 0.6 3.9e-23 81.4 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 OAJ12609.1 - 6.2e-05 22.7 2.1 0.085 12.6 0.0 2.2 1 1 1 2 2 2 2 Septum formation initiator SesA PF17107.5 OAJ12609.1 - 0.0037 17.4 0.2 1.3 9.3 0.1 2.1 2 0 0 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases ADIP PF11559.8 OAJ12609.1 - 0.0052 16.9 0.9 2.6 8.1 0.0 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 OAJ12609.1 - 0.03 14.2 0.9 0.06 13.3 0.9 1.5 1 1 0 1 1 1 0 Prefoldin subunit KASH_CCD PF14662.6 OAJ12609.1 - 0.044 13.6 3.5 0.085 12.7 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc24 PF08286.11 OAJ12609.1 - 0.055 13.7 3.2 3.9 7.8 0.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Lipoprotein_18 PF06804.11 OAJ12609.1 - 0.058 12.4 0.3 0.069 12.2 0.3 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein DUF4164 PF13747.6 OAJ12609.1 - 0.068 13.5 4.7 2.9 8.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.12 OAJ12609.1 - 0.11 13.1 2.2 4.8 7.9 0.0 2.4 2 1 0 2 2 2 0 SlyX DHR10 PF18595.1 OAJ12609.1 - 0.15 12.2 4.3 2 8.5 0.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 OAJ12609.1 - 0.24 11.4 1.5 1.6 8.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAJ12609.1 - 0.4 9.5 4.0 2.8 6.7 4.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Cue1_U7BR PF18499.1 OAJ12610.1 - 0.034 14.2 2.8 0.067 13.2 2.8 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 DUF4834 PF16118.5 OAJ12610.1 - 1.3 10.0 3.3 2.9 8.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Helicase_C PF00271.31 OAJ12636.1 - 3.8e-13 49.7 0.0 8.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ12636.1 - 1.1e-10 41.5 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ12636.1 - 3.8e-05 23.7 0.0 6.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OAJ12636.1 - 0.23 11.1 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Nup35_RRM PF05172.13 OAJ12638.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ASFV_L11L PF05293.11 OAJ12638.1 - 2.4 8.6 3.9 0.79 10.1 0.1 2.2 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein MULE PF10551.9 OAJ12651.1 - 1.5e-17 63.8 0.0 4.4e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ12651.1 - 5.4e-11 42.0 0.0 1.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 OAJ12651.1 - 9.2e-06 25.2 0.3 2.3e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.15 OAJ12651.1 - 0.0023 18.6 0.1 0.0048 17.6 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_Tnp_IS240 PF13610.6 OAJ12651.1 - 0.03 14.6 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 DDE domain DDE_Tnp_ISL3 PF01610.17 OAJ12651.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Transposase FAD_binding_1 PF00667.20 OAJ12652.1 - 9.4e-29 100.6 0.0 1.4e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAJ12652.1 - 1.4e-24 86.9 0.0 3.2e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAJ12652.1 - 4.8e-07 30.4 0.0 1.5e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAJ12652.1 - 0.0049 17.1 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain BLOC1_2 PF10046.9 OAJ12653.1 - 0.057 13.7 3.0 0.096 13.0 3.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 U79_P34 PF03064.16 OAJ12653.1 - 0.21 10.9 8.1 0.3 10.4 8.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spc7 PF08317.11 OAJ12653.1 - 0.38 9.6 9.0 0.49 9.2 9.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HSP70 PF00012.20 OAJ12653.1 - 0.9 7.6 7.7 1.1 7.4 7.7 1.0 1 0 0 1 1 1 0 Hsp70 protein XkdW PF09636.10 OAJ12653.1 - 2.7 8.1 8.1 1.3 9.2 2.6 2.1 1 1 1 2 2 2 0 XkdW protein MatP_C PF17414.2 OAJ12653.1 - 3.4 7.9 5.8 3 8.1 2.9 2.2 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain AMP-binding PF00501.28 OAJ12663.1 - 2.1e-25 89.2 0.0 1.3e-24 86.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ12663.1 - 1.1e-22 80.4 0.0 2.5e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 OAJ12663.1 - 3.8e-08 33.6 0.1 7.1e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAJ12663.1 - 1.8e-06 27.6 0.0 6.8e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ12663.1 - 0.0094 15.9 0.2 0.083 12.8 0.0 2.4 3 0 0 3 3 3 1 KR domain Aldo_ket_red PF00248.21 OAJ12664.1 - 8.8e-63 212.2 0.0 1.1e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADK PF00406.22 OAJ12665.1 - 2.7e-44 150.9 0.1 2.3e-23 83.0 0.0 2.1 1 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OAJ12665.1 - 5.1e-34 117.6 0.4 6.5e-32 110.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ12665.1 - 4.3e-12 46.7 0.0 7.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAJ12665.1 - 3.4e-07 30.1 0.2 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 OAJ12665.1 - 0.0014 18.8 0.0 0.0082 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAJ12665.1 - 0.032 13.5 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 OAJ12665.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 OAJ12665.1 - 0.18 12.2 0.3 0.28 11.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.21 OAJ12666.1 - 1.5e-37 128.8 15.5 2.6e-37 128.1 15.5 1.3 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 OAJ12666.1 - 0.058 13.0 16.8 0.15 11.6 5.5 2.1 1 1 1 2 2 2 0 PspA/IM30 family TPR_MLP1_2 PF07926.12 OAJ12666.1 - 0.17 12.0 9.2 0.61 10.2 8.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 OAJ12666.1 - 0.3 11.0 3.2 15 5.6 0.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YlqD PF11068.8 OAJ12666.1 - 1.1 9.7 12.7 3 8.2 10.0 2.1 1 1 1 2 2 2 0 YlqD protein OmpH PF03938.14 OAJ12666.1 - 4 7.8 14.3 1.9 8.9 2.6 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.6 OAJ12666.1 - 7.9 5.8 11.3 1.5 8.1 3.0 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding MULE PF10551.9 OAJ12667.1 - 1.1e-23 83.5 0.2 3.2e-23 82.0 0.2 1.9 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ12667.1 - 0.00092 18.2 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Transposase, Mutator family DUF1320 PF07030.12 OAJ12667.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Methyltransf_3 PF01596.17 OAJ12668.1 - 1.1e-46 158.6 0.0 1.6e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAJ12668.1 - 9.2e-12 45.9 0.0 1.6e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ12668.1 - 0.054 13.3 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-CHCC PF10276.9 OAJ12669.1 - 1.1e-17 63.7 1.5 1.7e-17 63.1 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain Mito_carr PF00153.27 OAJ12683.1 - 1.8e-47 159.2 2.9 6.3e-16 58.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TrkH PF02386.16 OAJ12684.1 - 2.5e-104 349.5 11.9 2.7e-102 342.8 2.2 2.1 2 0 0 2 2 2 2 Cation transport protein SRP-alpha_N PF04086.13 OAJ12684.1 - 0.022 14.7 2.4 0.042 13.8 2.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TB2_DP1_HVA22 PF03134.19 OAJ12684.1 - 0.24 11.4 3.9 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 TB2/DP1, HVA22 family ERO1 PF04137.15 OAJ12685.1 - 1.7e-121 405.7 0.0 4.7e-120 401.0 0.0 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) LCAT PF02450.15 OAJ12686.1 - 5.4e-89 299.1 0.1 1.7e-87 294.2 0.1 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1275 PF06912.11 OAJ12687.1 - 1e-29 103.8 14.3 1.3e-29 103.5 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) BT1 PF03092.16 OAJ12687.1 - 0.11 10.7 5.8 0.097 10.9 0.7 2.3 2 0 0 2 2 2 0 BT1 family Collectrin PF16959.5 OAJ12687.1 - 0.17 11.6 1.2 0.28 10.9 1.2 1.3 1 0 0 1 1 1 0 Renal amino acid transporter YwiC PF14256.6 OAJ12687.1 - 0.19 12.1 4.8 0.43 10.9 4.8 1.7 1 1 0 1 1 1 0 YwiC-like protein ATP-grasp_2 PF08442.10 OAJ12688.1 - 8.4e-67 224.7 0.3 1.4e-66 223.9 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 OAJ12688.1 - 2.4e-23 82.7 0.8 4.3e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAJ12688.1 - 2.3e-11 43.6 0.1 4.4e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAJ12688.1 - 0.0014 18.5 0.1 0.0033 17.2 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 OAJ12688.1 - 0.031 13.8 0.1 0.079 12.4 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OAJ12688.1 - 0.096 12.3 0.1 0.27 10.8 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain NDC10_II PF16787.5 OAJ12702.1 - 3.5e-58 197.2 0.0 5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Clusterin PF01093.17 OAJ12702.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Clusterin Transposase_21 PF02992.14 OAJ12703.1 - 0.00069 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 CDC45 PF02724.14 OAJ12704.1 - 0.047 12.0 4.7 0.071 11.4 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein LolA_like PF17131.4 OAJ12705.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein ABC_membrane_3 PF13748.6 OAJ12714.1 - 0.055 12.7 0.3 0.1 11.8 0.3 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region TPR_12 PF13424.6 OAJ12715.1 - 1.9e-12 47.3 13.2 6.8e-07 29.5 5.2 4.4 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ12715.1 - 1e-10 41.1 5.2 7.5e-05 22.5 0.6 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ12715.1 - 1.7e-07 30.8 4.1 0.0091 16.0 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ12715.1 - 0.00011 21.8 0.1 0.17 11.8 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ12715.1 - 0.00098 19.2 1.2 0.28 11.2 0.6 2.6 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 OAJ12715.1 - 0.0033 17.5 1.2 2.3 8.3 0.0 3.1 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 OAJ12715.1 - 0.012 16.3 5.4 2.4 9.2 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Vps4_C PF09336.10 OAJ12715.1 - 0.013 15.4 0.0 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain TPR_8 PF13181.6 OAJ12715.1 - 0.017 15.3 2.8 2.1 8.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ12715.1 - 0.06 14.0 6.2 2.2 9.0 1.0 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ12715.1 - 0.073 13.7 2.1 35 5.4 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ12715.1 - 0.089 12.9 2.4 8.3 6.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 OAJ12715.1 - 0.14 12.6 4.3 1.4 9.4 0.1 3.5 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TPR_11 PF13414.6 OAJ12715.1 - 0.22 11.2 1.2 23 4.8 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 OAJ12715.1 - 0.24 12.1 2.5 1.1e+02 3.7 0.0 4.7 5 2 0 5 5 5 0 Tetratricopeptide repeat Helicase_C PF00271.31 OAJ12716.1 - 7.2e-16 58.5 0.0 1.4e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAJ12716.1 - 7.2e-13 48.8 0.7 2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OAJ12716.1 - 1.4e-07 31.5 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ12716.1 - 4.6e-06 27.0 0.0 1.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 OAJ12716.1 - 0.0094 16.3 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_16 PF13191.6 OAJ12716.1 - 0.023 15.1 4.4 0.033 14.6 0.1 3.0 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 OAJ12716.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 OAJ12716.1 - 0.06 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 KaiC IMS PF00817.20 OAJ12717.1 - 5.3e-39 133.6 0.0 1.2e-38 132.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ12717.1 - 8.8e-12 45.8 0.0 3.1e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 OAJ12717.1 - 2.1e-07 31.2 1.0 4.4e-07 30.2 1.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 OAJ12717.1 - 0.0015 17.9 0.6 0.06 12.8 0.2 3.7 3 0 0 3 3 3 1 Ubiquitin binding region DUF1805 PF08827.11 OAJ12717.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) TilS PF09179.11 OAJ12717.1 - 0.14 12.7 0.7 1.2 9.7 0.1 2.7 2 0 0 2 2 2 0 TilS substrate binding domain mCpol PF18182.1 OAJ12717.1 - 0.2 12.0 0.0 0.57 10.5 0.0 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain AAA_5 PF07728.14 OAJ12728.1 - 4.8e-36 123.8 0.0 6.1e-28 97.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TENA_THI-4 PF03070.16 OAJ12742.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF370 PF04025.12 OAJ12743.1 - 0.079 13.1 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF370) Ribosomal_S8 PF00410.19 OAJ12754.1 - 2e-21 76.2 0.0 3.4e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 OAJ12755.1 - 3.8e-59 198.0 0.0 4.6e-59 197.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosom_S12_S23 PF00164.25 OAJ12756.1 - 1.4e-33 114.9 0.1 1.9e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 FAM176 PF14851.6 OAJ12757.1 - 2.9 7.5 7.5 11 5.6 0.8 3.1 3 0 0 3 3 3 0 FAM176 family WD40 PF00400.32 OAJ12773.1 - 3.5e-57 189.0 12.3 1.1e-08 35.6 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12773.1 - 1.5e-20 73.3 0.0 1.8e-05 25.0 0.0 6.3 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 OAJ12773.1 - 1.9e-18 66.5 2.3 1.9e-18 66.5 2.3 2.3 2 0 0 2 2 2 1 Tup N-terminal WD40_like PF17005.5 OAJ12773.1 - 1.4e-11 44.3 0.0 0.0049 16.2 0.0 4.5 5 0 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 OAJ12773.1 - 8.8e-08 31.5 0.0 1.2 8.0 0.0 5.8 3 3 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAJ12773.1 - 1.5e-05 24.8 0.2 20 5.3 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TFIIA PF03153.13 OAJ12773.1 - 0.00058 20.0 46.0 0.00058 20.0 46.0 2.9 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit Nup160 PF11715.8 OAJ12773.1 - 0.01 14.6 0.2 5 5.6 0.1 3.1 1 1 0 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OAJ12773.1 - 0.077 11.5 0.1 0.26 9.8 0.1 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain Apt1 PF10351.9 OAJ12773.1 - 3.4 6.4 16.0 5.5 5.7 16.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain tRNA-synt_2b PF00587.25 OAJ12787.1 - 9.7e-17 61.5 0.0 9.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) TMF_TATA_bd PF12325.8 OAJ12787.1 - 0.044 14.0 0.2 0.076 13.2 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AA_permease PF00324.21 OAJ12790.1 - 1.4e-121 406.5 37.9 1.7e-121 406.2 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ12790.1 - 2.5e-35 122.2 42.4 3.1e-35 121.8 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 OAJ12790.1 - 0.22 12.3 9.5 3.8 8.3 0.2 3.8 3 0 0 3 3 3 0 PrgI family protein HhH-GPD PF00730.25 OAJ12791.1 - 2.1e-09 37.8 0.0 4.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Flot PF15975.5 OAJ12791.1 - 0.045 13.9 1.6 3.1 8.0 0.5 2.4 2 0 0 2 2 2 0 Flotillin DUF3909 PF13077.6 OAJ12791.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) Macoilin PF09726.9 OAJ12791.1 - 1.8 7.0 10.6 0.48 8.9 4.3 2.0 2 0 0 2 2 2 0 Macoilin family DPM3 PF08285.11 OAJ12792.1 - 6.4e-30 103.2 0.0 7.1e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ATG_C PF09333.11 OAJ12793.1 - 1.5e-29 102.2 0.6 4.6e-29 100.6 0.2 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 OAJ12793.1 - 0.00017 21.3 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 OAJ12793.1 - 0.0054 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Fib_alpha PF08702.10 OAJ12793.1 - 0.036 14.2 0.2 0.069 13.3 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 OAJ12793.1 - 0.23 11.6 1.5 0.5 10.5 1.5 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Keratin_2_head PF16208.5 OAJ12793.1 - 3.3 7.8 30.7 0.14 12.3 12.6 3.2 3 0 0 3 3 3 0 Keratin type II head eIF-1a PF01176.19 OAJ12794.1 - 2.2e-21 75.4 0.0 3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Tubulin_3 PF14881.6 OAJ12804.1 - 7.7e-29 100.7 14.0 3.6e-19 69.1 11.0 4.3 2 1 0 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.9 OAJ12804.1 - 1.8e-26 92.8 0.0 6.8e-26 90.9 0.0 2.1 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Toxin_29 PF08116.11 OAJ12805.1 - 0.31 11.1 0.0 0.31 11.1 0.0 5.5 5 1 1 6 6 6 0 PhTx neurotoxin family UPF0506 PF11703.8 OAJ12805.1 - 2.3 8.6 42.8 0.32 11.4 7.1 4.7 2 2 2 4 4 4 0 UPF0506 zf-Sec23_Sec24 PF04810.15 OAJ12806.1 - 0.13 12.4 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Mannosidase_ig PF17786.1 OAJ12807.1 - 3.3e-09 37.2 0.2 9.8e-09 35.7 0.2 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 OAJ12807.1 - 4.5e-08 32.7 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain MT-A70 PF05063.14 OAJ12808.1 - 1.3e-49 168.4 0.0 9.5e-34 116.8 0.0 2.2 2 0 0 2 2 2 2 MT-A70 HHH PF00633.23 OAJ12822.1 - 0.016 15.0 0.1 0.043 13.7 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 OAJ12822.1 - 0.12 13.0 0.4 1.3 9.7 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain HCNGP PF07818.13 OAJ12824.1 - 2.6e-07 31.2 0.0 4.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein FAM220 PF15487.6 OAJ12824.1 - 0.093 12.4 4.6 0.05 13.2 2.0 1.7 1 1 1 2 2 2 0 FAM220 family Apolipoprotein PF01442.18 OAJ12825.1 - 0.00035 20.5 9.9 0.00045 20.1 9.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAJ12825.1 - 0.019 15.0 6.9 0.13 12.3 2.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3461 PF11944.8 OAJ12825.1 - 0.035 14.3 1.5 0.065 13.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF1640 PF07798.11 OAJ12825.1 - 0.045 13.8 5.7 0.24 11.4 5.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Gp-FAR-1 PF05823.12 OAJ12825.1 - 0.074 13.4 0.3 0.11 12.9 0.3 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cor1 PF04803.12 OAJ12825.1 - 0.076 13.2 0.9 0.076 13.2 0.9 2.1 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Fzo_mitofusin PF04799.13 OAJ12825.1 - 0.11 12.0 6.3 0.087 12.4 3.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region Bacillus_HBL PF05791.11 OAJ12825.1 - 0.24 11.2 4.6 0.41 10.5 2.2 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3907 PF13047.6 OAJ12825.1 - 0.29 11.1 1.6 14 5.6 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3907) Helitron_like_N PF14214.6 OAJ12826.1 - 2.1e-22 80.3 0.0 5e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ12826.1 - 2.2e-22 79.8 0.0 2.7e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 OAJ12826.1 - 9.8e-13 48.2 1.5 1.4e-12 47.8 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ12826.1 - 6.3e-08 33.1 0.4 4.7e-07 30.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OAJ12826.1 - 0.0013 19.2 0.0 0.0064 16.9 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 OAJ12826.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.14 OAJ12826.1 - 0.075 13.0 0.1 0.27 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAJ12826.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain COS PF18568.1 OAJ12828.1 - 0.044 13.7 0.3 5.9 6.9 0.0 2.2 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain Pap_E4 PF02711.14 OAJ12839.1 - 6 7.9 11.6 17 6.5 10.9 2.1 1 1 0 1 1 1 0 E4 protein ABC_tran PF00005.27 OAJ12840.1 - 1.9e-15 57.6 0.1 2.4e-13 50.8 0.0 3.3 2 2 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAJ12840.1 - 1.5e-08 34.9 7.1 0.01 15.6 0.3 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAJ12840.1 - 3.9e-06 27.0 0.0 0.037 14.3 0.0 2.9 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAJ12840.1 - 0.00031 21.3 0.1 0.00057 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAJ12840.1 - 0.003 17.2 0.1 0.0063 16.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ12840.1 - 0.0044 16.8 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAJ12840.1 - 0.0053 16.3 1.3 0.2 11.2 0.1 2.6 3 0 0 3 3 3 1 AAA domain SRPRB PF09439.10 OAJ12840.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SMC_N PF02463.19 OAJ12840.1 - 0.031 13.7 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.21 OAJ12840.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_24 PF13479.6 OAJ12840.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAJ12840.1 - 0.15 11.1 1.2 0.22 10.6 0.0 1.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAJ12840.1 - 0.25 10.8 0.0 1.1 8.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region CRAL_TRIO PF00650.20 OAJ12841.1 - 1.5e-28 99.6 0.0 2.7e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ12841.1 - 5.7e-09 36.0 0.6 1.8e-08 34.4 0.4 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ12841.1 - 3.4e-06 27.3 0.0 5.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain AMPKBI PF04739.15 OAJ12842.1 - 1e-26 92.9 0.1 2.6e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 OAJ12842.1 - 1.8e-26 92.2 0.0 3.5e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 OAJ12842.1 - 0.0051 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MF_alpha_N PF05436.11 OAJ12844.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Kdo PF06293.14 OAJ12855.1 - 4e-06 26.3 0.0 5.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAJ12855.1 - 6.6e-05 22.4 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAJ12855.1 - 0.00027 19.9 0.0 0.00036 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ12855.1 - 0.0023 17.9 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OAJ12855.1 - 0.0037 16.6 0.0 0.0072 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.18 OAJ12856.1 - 7.5e-45 153.5 0.1 1.1e-44 153.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.26 OAJ12857.1 - 8e-14 51.6 4.9 1.9e-13 50.4 3.4 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ12857.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4813 PF16072.5 OAJ12857.1 - 0.59 9.7 7.2 0.041 13.6 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Pkinase PF00069.25 OAJ12859.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12859.1 - 0.00061 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ12859.1 - 0.032 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ12859.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BPL_LplA_LipB PF03099.19 OAJ12860.1 - 0.00038 20.4 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 OAJ12860.1 - 0.14 12.2 0.0 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Kdo PF06293.14 OAJ12861.1 - 2.6e-05 23.7 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAJ12861.1 - 0.00017 21.0 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAJ12861.1 - 0.00067 18.5 0.0 0.00089 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OAJ12861.1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 OAJ12861.1 - 0.035 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_ab PF00006.25 OAJ12875.1 - 2.4e-05 24.1 0.0 2.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain RRM_1 PF00076.22 OAJ12876.1 - 3.4e-27 94.1 0.3 2e-16 59.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ12876.1 - 0.00025 21.1 0.0 0.00025 21.1 0.0 2.7 3 0 0 3 3 2 1 RNA binding motif TFIIA PF03153.13 OAJ12876.1 - 0.0003 20.9 35.8 0.0003 20.9 35.8 2.8 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.6 OAJ12876.1 - 0.0026 17.7 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ12876.1 - 0.036 14.2 0.1 1.5 9.0 0.1 2.9 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 OAJ12876.1 - 0.16 11.8 0.0 0.66 9.9 0.0 2.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif PAT1 PF09770.9 OAJ12876.1 - 1.1 7.5 44.8 0.065 11.5 28.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.16 OAJ12876.1 - 2.3 7.0 4.8 3.1 6.6 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Velvet PF11754.8 OAJ12876.1 - 4.1 7.3 24.5 0.37 10.7 11.5 2.8 2 0 0 2 2 2 0 Velvet factor Cellulose_synt PF03552.14 OAJ12876.1 - 4.2 5.8 5.8 6.3 5.2 5.8 1.1 1 0 0 1 1 1 0 Cellulose synthase SID-1_RNA_chan PF13965.6 OAJ12876.1 - 5.6 5.3 5.8 8.9 4.6 5.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF648 PF04890.13 OAJ12876.1 - 7.5 6.2 16.0 12 5.6 16.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF1729 PF08354.10 OAJ12877.1 - 4.4e-36 124.5 0.0 5.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) UPF0061 PF02696.14 OAJ12877.1 - 1.9e-05 23.7 0.1 2.6e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family He_PIG PF05345.12 OAJ12878.1 - 7.9e-14 51.6 11.8 2.2e-05 24.6 0.2 4.1 3 0 0 3 3 3 3 Putative Ig domain IMUP PF15761.5 OAJ12893.1 - 1.6 9.5 7.9 1.2 9.8 5.9 1.9 1 1 0 1 1 1 0 Immortalisation up-regulated protein Glyco_hydro_47 PF01532.20 OAJ12894.1 - 2.5e-150 501.4 0.0 2.9e-150 501.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Myb_DNA-bind_4 PF13837.6 OAJ12895.1 - 0.003 17.9 2.2 0.04 14.3 0.0 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 OAJ12896.1 - 1.7e-21 76.6 0.0 1.7e-21 76.6 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ12896.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.8 3 0 0 3 3 3 0 Transposase DDE domain Macoilin PF09726.9 OAJ12897.1 - 2.2 6.8 9.6 0.47 9.0 6.3 1.6 2 0 0 2 2 2 0 Macoilin family TauD PF02668.16 OAJ12898.1 - 1.8e-51 175.5 2.8 2.3e-51 175.2 2.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Carn_acyltransf PF00755.20 OAJ12899.1 - 1.1e-161 539.5 0.0 1.2e-161 539.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DDE_1 PF03184.19 OAJ12917.1 - 0.00046 19.9 0.0 0.00053 19.7 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease SSP160 PF06933.11 OAJ12921.1 - 1.9 6.6 14.1 2.4 6.2 14.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF913 PF06025.12 OAJ12922.1 - 2.3 7.1 6.0 2.6 6.9 6.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MDM10 PF12519.8 OAJ12922.1 - 8.7 5.1 7.8 8.2 5.2 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FGF-BP1 PF06473.12 OAJ12922.1 - 9.4 6.0 19.5 35 4.1 19.5 1.8 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) GNAT_acetyltr_2 PF13718.6 OAJ12922.1 - 9.5 5.5 8.3 4.6 6.6 5.4 1.8 2 1 1 3 3 3 0 GNAT acetyltransferase 2 HA2 PF04408.23 OAJ12930.1 - 2.3e-19 69.6 0.0 4.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ12930.1 - 4.5e-19 68.6 0.0 1.6e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ12930.1 - 8.5e-16 58.3 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ12930.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ12930.1 - 1.4e-05 25.4 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ12930.1 - 0.0075 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ12930.1 - 0.029 14.4 0.0 0.29 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ12930.1 - 0.061 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ12930.1 - 0.14 11.6 0.0 0.77 9.2 0.0 2.2 2 1 1 3 3 3 0 PhoH-like protein Cwf_Cwc_15 PF04889.12 OAJ12931.1 - 0.0067 16.2 9.4 0.0067 16.2 9.4 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein SLC12 PF03522.15 OAJ12931.1 - 0.65 8.9 9.2 0.096 11.7 1.9 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Presenilin PF01080.17 OAJ12931.1 - 2 7.1 8.6 0.032 13.0 1.3 1.6 2 0 0 2 2 2 0 Presenilin DUF4692 PF15763.5 OAJ12931.1 - 4 7.9 12.9 9.8 6.6 12.9 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FAM60A PF15396.6 OAJ12931.1 - 4.1 7.3 13.9 0.14 12.2 3.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A SR-25 PF10500.9 OAJ12931.1 - 8.8 5.9 43.0 0.14 11.7 29.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MAPEG PF01124.18 OAJ12932.1 - 5e-24 84.7 1.4 5.9e-24 84.4 1.4 1.1 1 0 0 1 1 1 1 MAPEG family LAG1-DNAbind PF09271.11 OAJ12934.1 - 6.5e-22 78.8 0.0 8.6e-21 75.2 0.0 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 OAJ12934.1 - 2.6e-14 53.7 0.0 5.6e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain TPR_12 PF13424.6 OAJ12936.1 - 7.1e-09 35.8 33.8 0.00028 21.1 6.4 7.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ12936.1 - 2.7e-07 30.3 22.3 0.17 11.8 1.5 7.6 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ12936.1 - 0.0013 18.4 13.9 7.1 6.6 0.6 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ12936.1 - 0.0014 19.3 19.7 4.4 8.4 1.3 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OAJ12936.1 - 0.0017 17.2 3.5 0.35 9.6 0.1 3.6 3 2 1 4 4 4 1 Fungal protein kinase SHNi-TPR PF10516.9 OAJ12936.1 - 0.002 17.6 7.4 1.3 8.6 0.1 4.4 5 0 0 5 5 5 2 SHNi-TPR DUF3856 PF12968.7 OAJ12936.1 - 0.0023 18.0 6.3 1.7 8.7 0.4 3.6 1 1 3 4 4 4 3 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 OAJ12936.1 - 0.0052 16.8 15.3 6.8 6.8 0.2 6.4 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 OAJ12936.1 - 0.069 13.3 27.4 13 6.2 1.1 8.6 8 2 1 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ12936.1 - 0.38 11.1 17.6 7.9 7.0 2.1 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat PTPlike_phytase PF14566.6 OAJ12950.1 - 4.3e-120 397.3 0.0 1.8e-47 161.3 0.0 4.0 3 1 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 OAJ12950.1 - 0.0047 16.5 0.1 11 5.5 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ12950.1 - 0.0057 16.5 0.0 2.5 7.9 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain MutS_V PF00488.21 OAJ12952.1 - 1.1e-42 146.2 0.0 2.8e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ12952.1 - 1.4e-22 80.9 0.2 1.4e-22 80.9 0.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OAJ12952.1 - 7.7e-06 26.2 1.4 0.096 13.0 1.0 3.7 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 OAJ12952.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV SMC_N PF02463.19 OAJ12952.1 - 0.012 15.1 0.1 1.8 7.9 0.1 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ12952.1 - 0.11 12.8 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain CD24 PF14984.6 OAJ12952.1 - 0.41 10.9 5.5 1.7 8.9 5.5 2.1 1 0 0 1 1 1 0 CD24 protein DHHA2 PF02833.14 OAJ12966.1 - 3.2e-17 63.1 0.0 7.1e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 DHHA2 domain F-box-like PF12937.7 OAJ12967.1 - 0.041 13.8 0.5 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 F-box-like EB PF01683.18 OAJ12968.1 - 0.00092 19.5 43.6 0.17 12.2 4.2 4.1 2 2 1 3 3 3 3 EB module UPF0506 PF11703.8 OAJ12968.1 - 0.58 10.6 38.9 0.27 11.7 2.9 4.5 3 1 1 4 4 4 0 UPF0506 LEAP-2 PF07359.11 OAJ12968.1 - 0.68 9.8 28.0 0.88 9.5 2.7 3.7 3 1 1 4 4 4 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) HIG_1_N PF04588.13 OAJ12969.1 - 1e-05 25.7 1.1 2.5e-05 24.4 1.1 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 OAJ12969.1 - 0.017 15.0 0.5 0.032 14.1 0.1 1.6 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein TctA PF01970.16 OAJ12969.1 - 0.037 12.7 0.0 0.059 12.1 0.0 1.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Aldo_ket_red PF00248.21 OAJ12970.1 - 2e-28 99.4 0.0 9.4e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Aldo/keto reductase family DUF1640 PF07798.11 OAJ12971.1 - 1.7e-48 165.0 1.6 2.2e-48 164.6 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) F-box-like PF12937.7 OAJ12972.1 - 0.00012 21.9 0.1 0.00025 20.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ12972.1 - 0.00031 20.6 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box PF00646.33 OAJ12973.1 - 3.5e-06 26.7 0.0 9.3e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ12973.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like Dec-1 PF04624.14 OAJ12974.1 - 0.093 12.6 0.3 0.093 12.6 0.3 2.3 2 0 0 2 2 2 0 Dec-1 repeat T3SSipB PF16535.5 OAJ12974.1 - 0.8 10.2 6.4 1.7 9.1 6.4 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB zf-C3HC4 PF00097.25 OAJ12987.1 - 6.5e-08 32.3 12.4 8.5e-08 31.9 9.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ12987.1 - 9.6e-07 28.7 14.1 4.8e-06 26.5 9.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ12987.1 - 1.5e-06 28.0 9.2 1.5e-06 28.0 9.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ12987.1 - 1.7e-06 27.8 3.9 3.6e-06 26.7 3.1 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAJ12987.1 - 6e-06 26.3 9.2 6e-06 26.3 9.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ12987.1 - 1.6e-05 24.7 13.8 3.6e-05 23.6 10.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ12987.1 - 5e-05 23.3 4.9 0.00013 21.9 3.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SAP PF02037.27 OAJ12987.1 - 6.3e-05 22.6 0.8 0.00023 20.8 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-C3HC4_3 PF13920.6 OAJ12987.1 - 6.3e-05 22.7 11.6 0.00071 19.4 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ12987.1 - 0.00014 22.1 15.6 0.00031 21.0 10.1 2.3 2 0 0 2 2 2 1 Ring finger domain Serglycin PF04360.12 OAJ12987.1 - 0.003 17.5 1.1 0.0071 16.3 1.1 1.6 1 0 0 1 1 1 1 Serglycin zf-Nse PF11789.8 OAJ12987.1 - 0.0058 16.4 4.4 0.0058 16.4 4.4 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.6 OAJ12987.1 - 0.0071 16.1 0.3 2.9 7.7 0.1 3.3 3 0 0 3 3 3 1 zinc-ribbon domain Prok-RING_4 PF14447.6 OAJ12987.1 - 0.012 15.5 11.2 1.4 8.8 7.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ12987.1 - 0.11 12.8 10.1 0.068 13.5 5.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAJ12987.1 - 1.2 9.3 6.0 2.7 8.2 6.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 OAJ12987.1 - 1.3 9.2 10.4 8.2 6.7 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.6 OAJ12987.1 - 1.3 8.9 11.3 3.3 7.6 8.8 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.6 OAJ12987.1 - 1.3 10.0 0.0 1.3 10.0 0.0 3.9 3 1 1 4 4 2 0 C2H2-type zinc finger zf-RING_2 PF13639.6 OAJ12989.1 - 3.7e-10 40.0 8.1 5.5e-10 39.4 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ12989.1 - 3.5e-09 36.4 4.7 5.1e-09 35.8 4.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ12989.1 - 6.6e-09 35.6 6.0 9.9e-09 35.0 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ12989.1 - 3.3e-08 33.2 7.6 6.6e-08 32.3 7.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ12989.1 - 4.5e-08 32.8 4.8 7.2e-08 32.2 4.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ12989.1 - 6.4e-08 32.8 5.1 1.1e-07 32.0 5.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAJ12989.1 - 7.8e-08 32.2 2.2 1.4e-07 31.5 0.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ12989.1 - 1.8e-07 30.9 6.1 2.9e-07 30.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ12989.1 - 0.0002 21.5 2.7 0.0002 21.5 2.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAJ12989.1 - 0.0048 16.7 6.6 0.0078 16.0 6.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OAJ12989.1 - 0.0091 15.7 3.3 0.016 15.0 1.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_10 PF16685.5 OAJ12989.1 - 0.014 15.5 4.4 0.027 14.6 4.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OAJ12989.1 - 0.015 15.3 2.3 0.025 14.6 2.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 OAJ12989.1 - 0.019 14.9 0.3 0.028 14.3 0.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) IBR PF01485.21 OAJ12989.1 - 0.036 14.3 4.4 0.072 13.3 4.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 OAJ12989.1 - 0.037 13.9 2.3 0.066 13.1 2.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rtf2 PF04641.12 OAJ12989.1 - 1.3 8.3 6.2 1.1 8.6 0.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Btz PF09405.10 OAJ12990.1 - 2.2e-06 28.0 0.1 2.2e-06 28.0 0.1 4.5 4 1 1 5 5 5 1 CASC3/Barentsz eIF4AIII binding NOA36 PF06524.12 OAJ12990.1 - 2 7.6 17.1 4.3 6.6 17.1 1.5 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OAJ12990.1 - 2.8 7.3 26.3 5.2 6.4 26.3 1.4 1 0 0 1 1 1 0 SDA1 GOLD_2 PF13897.6 OAJ12990.1 - 4.2 7.9 5.7 11 6.5 5.7 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RXT2_N PF08595.11 OAJ12990.1 - 5.1 7.1 6.3 55 3.8 7.7 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Sec15 PF04091.12 OAJ12991.1 - 0.029 13.8 2.0 0.097 12.1 0.0 2.4 3 0 0 3 3 3 0 Exocyst complex subunit Sec15-like REV1_C PF16727.5 OAJ12991.1 - 0.03 14.7 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Peptidase_S8 PF00082.22 OAJ13006.1 - 4e-37 128.1 3.6 6.5e-37 127.4 3.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OAJ13006.1 - 4.5e-26 90.7 0.2 8.8e-26 89.8 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OAJ13006.1 - 0.0045 17.7 2.2 0.047 14.5 2.2 2.4 1 1 0 1 1 1 1 Peptidase S8 pro-domain HlyE PF06109.13 OAJ13007.1 - 0.16 11.2 1.8 0.43 9.8 0.2 1.9 1 1 1 2 2 2 0 Haemolysin E (HlyE) Fungal_trans PF04082.18 OAJ13008.1 - 8e-11 41.5 0.0 1.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAJ13008.1 - 0.00043 20.6 5.9 0.072 13.6 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ13008.1 - 0.28 12.1 14.2 0.18 12.7 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Serglycin PF04360.12 OAJ13008.1 - 4.3 7.3 13.1 0.021 14.8 1.4 2.7 2 0 0 2 2 2 0 Serglycin F-box-like PF12937.7 OAJ13009.1 - 8.8e-12 44.7 0.1 8.8e-12 44.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ13009.1 - 1.4e-07 31.2 1.4 3.1e-07 30.1 0.1 2.1 2 0 0 2 2 2 1 F-box domain PQQ PF01011.21 OAJ13009.1 - 0.0037 17.1 0.0 0.77 9.8 0.0 2.6 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 OAJ13009.1 - 0.027 14.1 0.0 0.14 11.7 0.0 2.1 2 1 0 2 2 2 0 PQQ-like domain Usp PF00582.26 OAJ13010.1 - 0.00063 20.3 4.0 0.13 12.8 0.1 3.7 3 0 0 3 3 3 2 Universal stress protein family RuvX PF03652.15 OAJ13010.1 - 0.018 15.5 0.5 0.16 12.4 0.0 2.7 3 0 0 3 3 3 0 Holliday junction resolvase eIF-3c_N PF05470.12 OAJ13022.1 - 2.5e-181 604.0 4.1 2.5e-181 604.0 4.1 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAJ13022.1 - 9.3e-08 32.5 0.0 3.3e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 PCI domain CABIT PF12736.7 OAJ13022.1 - 0.026 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, DUF3439 PF11921.8 OAJ13022.1 - 2.2 8.3 6.5 0.13 12.2 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CDC45 PF02724.14 OAJ13022.1 - 5.1 5.3 21.5 9.8 4.3 21.3 1.5 1 1 0 1 1 1 0 CDC45-like protein Acyl-CoA_dh_1 PF00441.24 OAJ13023.1 - 9.4e-37 126.5 0.1 1.3e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ13023.1 - 7.2e-18 64.6 0.1 1.2e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAJ13023.1 - 3.7e-14 53.3 0.0 8.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ13023.1 - 5.4e-12 46.1 0.0 8.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RAMP4 PF06624.12 OAJ13024.1 - 4.8e-13 49.0 0.6 6.9e-13 48.5 0.6 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 UQ_con PF00179.26 OAJ13025.1 - 4.6e-44 149.5 0.0 5.3e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TCRP1 PF14944.6 OAJ13025.1 - 0.14 12.1 0.4 5.7 6.8 0.3 2.0 1 1 1 2 2 2 0 Tongue Cancer Chemotherapy Resistant Protein 1 Hydrolase_4 PF12146.8 OAJ13026.1 - 2.5e-12 46.6 0.0 4.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ13026.1 - 6.2e-12 46.6 0.1 8.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ13026.1 - 1.1e-10 41.7 0.2 2.3e-07 30.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ13026.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 OAJ13026.1 - 0.14 11.7 0.0 20 4.6 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 OAJ13026.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Orn_Arg_deC_N PF02784.16 OAJ13027.1 - 3.8e-25 88.7 0.0 5.5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 OAJ13027.1 - 0.0024 18.1 0.1 0.0057 16.9 0.1 1.6 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 OAJ13027.1 - 0.11 13.1 0.0 0.99 10.0 0.0 2.4 1 1 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension Peptidase_M48_N PF16491.5 OAJ13029.1 - 1.8e-58 197.5 3.2 3.4e-58 196.5 3.2 1.5 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAJ13029.1 - 3e-30 105.5 0.1 2.4e-23 82.9 0.0 2.9 2 1 0 2 2 2 2 Peptidase family M48 Peptidase_M56 PF05569.11 OAJ13029.1 - 0.0096 15.1 0.1 0.0096 15.1 0.1 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF1168 PF06658.12 OAJ13030.1 - 1.3e-39 135.1 12.1 1.3e-39 135.1 12.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) CENP-N PF05238.13 OAJ13030.1 - 0.097 12.0 5.2 0.11 11.7 5.2 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like PPL5 PF18168.1 OAJ13030.1 - 0.34 10.2 5.9 0.45 9.8 5.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF966 PF06136.13 OAJ13030.1 - 0.57 9.8 8.7 0.74 9.5 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 OAJ13030.1 - 0.6 8.8 2.3 0.82 8.4 2.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 OAJ13030.1 - 1.5 7.5 3.4 1.5 7.5 3.4 1.1 1 0 0 1 1 1 0 Presenilin TipE PF16972.5 OAJ13030.1 - 6.5 5.8 5.3 4.5 6.3 4.1 1.3 1 1 0 1 1 1 0 Na+ channel auxiliary subunit TipE THOC2_N PF16134.5 OAJ13030.1 - 7.2 5.1 6.5 10 4.6 6.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Phage_integrase PF00589.22 OAJ13043.1 - 1.8e-05 24.6 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Herpes_U44 PF04533.13 OAJ13044.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpes virus U44 protein WD40 PF00400.32 OAJ13045.1 - 1.3e-39 133.4 26.8 3.7e-08 33.9 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ13045.1 - 8.1e-16 58.1 2.2 0.00011 22.4 0.1 6.0 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ13045.1 - 8.5e-14 51.9 0.9 4.9e-08 33.1 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAJ13045.1 - 0.00011 21.3 3.4 0.024 13.6 0.3 3.5 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ13045.1 - 0.00025 20.5 0.0 0.05 12.9 0.0 2.7 2 1 0 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 OAJ13045.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region STAG PF08514.11 OAJ13046.1 - 3.7e-32 110.6 1.5 1.1e-31 109.1 1.5 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 OAJ13046.1 - 0.065 13.5 0.2 12 6.5 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat MA3 PF02847.17 OAJ13046.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 MA3 domain Peptidase_C48 PF02902.19 OAJ13047.1 - 4.5e-16 59.3 0.0 1.1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 OAJ13047.1 - 1.1e-12 48.1 1.9 4.6e-07 30.2 0.2 3.5 3 1 1 4 4 4 2 MULE transposase domain SWIM PF04434.17 OAJ13047.1 - 0.013 15.1 0.5 0.029 14.0 0.5 1.5 1 0 0 1 1 1 0 SWIM zinc finger PALP PF00291.25 OAJ13059.1 - 5.3e-62 209.9 0.5 1.8e-40 139.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Mit_ribos_Mrp51 PF11709.8 OAJ13061.1 - 0.0042 16.7 3.0 1.3 8.6 0.2 3.1 2 1 1 3 3 3 2 Mitochondrial ribosomal protein subunit zf-Mss51 PF13824.6 OAJ13062.1 - 5.5e-22 77.6 2.2 1.3e-21 76.5 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Calreticulin PF00262.18 OAJ13063.1 - 1.1e-160 534.5 11.6 1.4e-160 534.2 11.6 1.1 1 0 0 1 1 1 1 Calreticulin family DUF883 PF05957.13 OAJ13063.1 - 0.0031 18.1 2.7 0.0031 18.1 2.7 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) MtrD PF04207.12 OAJ13063.1 - 0.0036 17.0 0.7 0.0055 16.4 0.7 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D Rad52_Rad22 PF04098.15 OAJ13063.1 - 0.34 10.8 5.1 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Peptidase_S3 PF00944.19 OAJ13077.1 - 0.082 12.7 0.8 0.11 12.3 0.8 1.2 1 0 0 1 1 1 0 Alphavirus core protein DUF4813 PF16072.5 OAJ13077.1 - 0.49 10.0 8.1 0.55 9.9 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Coq4 PF05019.13 OAJ13078.1 - 1.6e-80 269.6 0.0 2.1e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MMS19_N PF14500.6 OAJ13079.1 - 2e-63 214.4 1.9 1.1e-62 212.0 1.9 2.1 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 OAJ13079.1 - 1.5e-28 100.1 0.0 2.6e-26 92.7 0.0 2.9 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal PUL PF08324.11 OAJ13079.1 - 7 5.8 7.5 1.3 8.2 1.3 2.6 2 1 1 3 3 3 0 PUL domain RNase_T PF00929.24 OAJ13080.1 - 1.2e-14 55.2 0.0 1.8e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OAJ13080.1 - 0.0017 18.1 0.0 0.0057 16.4 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease DUF3246 PF11596.8 OAJ13080.1 - 0.026 14.0 0.7 0.046 13.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ndc1_Nup PF09531.10 OAJ13080.1 - 0.066 11.9 0.5 0.079 11.6 0.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sporozoite_P67 PF05642.11 OAJ13080.1 - 0.65 8.0 4.5 1.2 7.1 3.8 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NOA36 PF06524.12 OAJ13080.1 - 1.8 7.8 5.6 2.5 7.4 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ13080.1 - 4.4 5.5 6.1 5.9 5.0 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_H_20C_C PF18088.1 OAJ13081.1 - 1.3e-35 123.1 0.0 1.5e-34 119.5 0.0 2.6 3 0 0 3 3 3 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 OAJ13081.1 - 5e-08 32.7 0.0 3.7e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain S36_mt PF10937.8 OAJ13081.1 - 1.3 10.7 6.3 0.22 13.1 1.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial SPX PF03105.19 OAJ13081.1 - 5.1 6.9 13.9 0.15 11.9 0.4 2.9 3 1 0 3 3 3 0 SPX domain Abhydrolase_3 PF07859.13 OAJ13082.1 - 8e-49 166.4 0.1 1.3e-48 165.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ13082.1 - 1.2e-12 47.4 0.0 2.9e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAJ13082.1 - 0.094 13.3 2.7 0.2 12.2 2.7 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family La PF05383.17 OAJ13094.1 - 2.5e-16 59.5 0.0 4.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 La domain CoA_binding_2 PF13380.6 OAJ13095.1 - 1.2e-32 112.8 0.1 1.4e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 OAJ13095.1 - 0.0007 20.2 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Flg_new PF09479.10 OAJ13095.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) NAD_kinase PF01513.21 OAJ13096.1 - 3.4e-73 246.4 0.0 1.6e-71 240.9 0.0 2.8 1 1 0 1 1 1 1 ATP-NAD kinase DNA_pol_phi PF04931.13 OAJ13096.1 - 0.7 7.9 22.0 1.3 7.0 22.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 OAJ13096.1 - 4.1 5.1 10.1 6.4 4.4 10.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 OAJ13096.1 - 8.2 5.1 9.1 13 4.5 9.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Stn1 PF10451.9 OAJ13097.1 - 1.2e-05 24.5 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 RMI2 PF16100.5 OAJ13097.1 - 0.00093 19.0 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 OAJ13097.1 - 0.0076 16.2 1.2 0.015 15.3 1.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PACT_coil_coil PF10495.9 OAJ13097.1 - 0.16 12.5 0.5 1.4 9.6 0.2 2.4 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein PAP2 PF01569.21 OAJ13098.1 - 3.5e-27 94.8 5.5 7e-27 93.8 5.5 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OAJ13098.1 - 0.01 15.6 10.0 0.038 13.7 10.0 2.0 1 1 0 1 1 1 0 PAP2 superfamily Mlh1_C PF16413.5 OAJ13110.1 - 8.4e-68 228.7 0.0 2.3e-66 224.0 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAJ13110.1 - 4.3e-31 107.1 0.0 7.1e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAJ13110.1 - 1.5e-12 47.5 0.0 6.7e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ13110.1 - 5.2e-08 33.4 0.0 8.7e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YL1 PF05764.13 OAJ13110.1 - 0.00013 22.2 22.1 0.00026 21.2 22.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 OAJ13110.1 - 0.00042 18.7 21.6 0.0006 18.2 21.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 OAJ13110.1 - 0.00056 18.4 16.6 0.0011 17.4 16.6 1.4 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 OAJ13110.1 - 0.00093 18.7 21.2 0.0016 17.9 21.2 1.3 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 OAJ13110.1 - 0.039 13.3 26.1 0.074 12.4 26.1 1.4 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 OAJ13110.1 - 0.041 12.3 22.4 0.063 11.7 22.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Cwf_Cwc_15 PF04889.12 OAJ13110.1 - 0.049 13.4 20.4 0.088 12.5 20.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LAP1C PF05609.12 OAJ13110.1 - 0.19 10.8 8.1 0.28 10.2 8.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PI3K_1B_p101 PF10486.9 OAJ13110.1 - 0.58 7.9 3.7 0.89 7.3 3.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 OAJ13110.1 - 0.93 8.0 27.3 1.7 7.1 27.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.22 OAJ13110.1 - 1 8.5 2.8 1.9 7.6 2.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 OAJ13110.1 - 1.1 8.8 29.8 1.9 8.0 29.6 1.5 1 1 0 1 1 1 0 PPP4R2 Vfa1 PF08432.10 OAJ13110.1 - 1.5 9.2 10.7 2.8 8.2 10.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.10 OAJ13110.1 - 2.6 7.4 19.5 4.1 6.7 19.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 OAJ13110.1 - 3.3 7.5 11.3 5.3 6.8 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SspB PF04386.13 OAJ13110.1 - 7.6 6.4 12.0 2.1e+02 1.7 0.0 2.5 2 0 0 2 2 2 0 Stringent starvation protein B Merozoite_SPAM PF07133.11 OAJ13110.1 - 7.8 6.5 44.6 14 5.6 44.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DCP1 PF06058.13 OAJ13111.1 - 3.7e-24 84.9 0.0 5.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Zn_clus PF00172.18 OAJ13112.1 - 2.2e-05 24.5 2.8 5.5e-05 23.2 2.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltrn_RNA_3 PF02598.17 OAJ13113.1 - 3e-96 322.3 0.0 3.7e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 OAJ13113.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 SpoU rRNA Methylase family PBP1_TM PF14812.6 OAJ13113.1 - 3.3 8.1 11.3 1 9.7 8.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NGP1NT PF08153.12 OAJ13114.1 - 2.7e-46 156.9 0.0 6.7e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAJ13114.1 - 2e-16 60.1 0.0 1.5e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 OAJ13114.1 - 0.00033 20.1 0.1 0.049 13.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 OAJ13114.1 - 0.00056 19.5 0.1 0.0013 18.3 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ13114.1 - 0.0007 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Utp14 PF04615.13 OAJ13114.1 - 0.16 10.5 22.5 0.2 10.2 21.5 1.6 2 0 0 2 2 2 0 Utp14 protein Dynamin_N PF00350.23 OAJ13114.1 - 0.39 10.8 6.1 0.78 9.8 0.0 4.0 4 1 1 5 5 5 0 Dynamin family MSC PF09402.10 OAJ13115.1 - 3.8e-41 141.7 0.0 2.5e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Man1-Src1p-C-terminal domain DinB_2 PF12867.7 OAJ13129.1 - 0.0013 19.2 0.3 0.0022 18.5 0.3 1.4 1 0 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.8 OAJ13129.1 - 0.0045 17.7 0.2 0.0075 17.0 0.2 1.3 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DASH_Dad3 PF08656.10 OAJ13130.1 - 5.3e-19 68.1 0.7 6.7e-19 67.8 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Forkhead PF00250.18 OAJ13131.1 - 5e-24 84.4 0.0 1.4e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Forkhead domain TFIIA PF03153.13 OAJ13131.1 - 0.0019 18.3 15.5 0.0019 18.3 15.5 2.3 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit eIF_4EBP PF05456.11 OAJ13131.1 - 0.018 15.0 1.1 0.018 15.0 1.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Spt20 PF12090.8 OAJ13131.1 - 0.65 9.6 26.0 1.4 8.4 26.0 1.5 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 OAJ13131.1 - 0.98 9.8 8.9 0.3 11.4 5.8 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like CCDC53 PF10152.9 OAJ13131.1 - 1.9 8.9 7.5 0.54 10.7 3.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Neur_chan_memb PF02932.16 OAJ13131.1 - 2.2 8.3 4.7 1.2 9.1 1.5 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 OAJ13131.1 - 3.3 6.6 9.6 5.8 5.8 9.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) API5 PF05918.11 OAJ13131.1 - 4 6.2 11.3 7.1 5.3 11.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) AAA_9 PF12781.7 OAJ13132.1 - 1.9e-74 249.5 3.7 9.2e-74 247.3 0.1 3.3 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 OAJ13132.1 - 2.6e-46 158.3 4.8 4.9e-46 157.3 4.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 OAJ13132.1 - 4.8e-41 141.0 0.7 8.2e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OAJ13132.1 - 2.7e-37 128.1 0.0 6.4e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OAJ13132.1 - 6.2e-29 100.5 0.0 1.3e-27 96.2 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OAJ13132.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DUF948 PF06103.11 OAJ13132.1 - 0.59 10.4 8.4 14 6.0 0.7 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OAJ13132.1 - 1.6 7.5 35.8 0.0096 14.8 12.0 3.8 4 0 0 4 4 4 0 Spc7 kinetochore protein LOH1CR12 PF10158.9 OAJ13132.1 - 2.4 8.2 7.1 0.51 10.4 0.5 2.9 3 0 0 3 3 3 0 Tumour suppressor protein Phlebovirus_NSM PF07246.11 OAJ13132.1 - 5.9 6.2 8.4 2.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Sugar_tr PF00083.24 OAJ13133.1 - 5.2e-72 243.1 8.7 4e-39 134.7 0.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ13133.1 - 5.8e-19 68.2 30.1 5.8e-19 68.2 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.31 OAJ13147.1 - 1.9e-11 44.3 0.0 4.5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ13147.1 - 8.7e-08 32.1 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase EspB PF05802.11 OAJ13147.1 - 0.33 10.9 3.2 0.57 10.1 3.2 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF4337 PF14235.6 OAJ13147.1 - 7.7 6.6 5.6 13 5.9 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UbiA PF01040.18 OAJ13149.1 - 7.9e-48 162.9 24.5 2.5e-46 158.0 20.4 2.1 2 0 0 2 2 2 2 UbiA prenyltransferase family Glyco_transf_20 PF00982.21 OAJ13150.1 - 2.6e-142 474.9 0.0 5.4e-131 437.5 0.0 2.5 2 1 0 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAJ13150.1 - 4.6e-74 248.5 0.0 7.4e-74 247.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAJ13150.1 - 0.00012 21.9 0.0 0.011 15.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAJ13150.1 - 0.0016 18.0 0.1 0.0089 15.6 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase rve_3 PF13683.6 OAJ13150.1 - 0.002 17.9 0.0 0.0057 16.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Protamine_P2 PF00841.19 OAJ13150.1 - 1.1 9.8 3.9 3.7 8.1 3.9 1.9 1 0 0 1 1 1 0 Sperm histone P2 zf-CCHC PF00098.23 OAJ13151.1 - 0.049 13.7 1.3 0.12 12.5 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle TAF4 PF05236.14 OAJ13151.1 - 0.18 11.5 2.3 0.49 10.1 2.3 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Arf PF00025.21 OAJ13167.1 - 4.6e-36 123.9 0.0 1.7e-24 86.2 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OAJ13167.1 - 1.9e-13 50.7 0.0 3.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ13167.1 - 4.6e-13 49.1 0.0 2.1e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 OAJ13167.1 - 3.5e-08 33.1 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ13167.1 - 3.5e-05 23.3 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ13167.1 - 7.8e-05 22.0 0.2 0.00024 20.4 0.1 1.8 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OAJ13167.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAJ13167.1 - 0.11 12.5 0.3 0.22 11.6 0.3 1.5 1 1 0 1 1 1 0 Dynamin family DPBB_1 PF03330.18 OAJ13168.1 - 0.0001 22.5 0.2 0.00059 20.1 0.2 2.2 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ13168.1 - 0.018 14.9 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 Barwin family DUF5061 PF16587.5 OAJ13168.1 - 0.047 13.7 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 17 kDa common-antigen outer membrane protein DUF1962 PF09227.10 OAJ13168.1 - 0.12 12.8 0.6 0.18 12.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) SLC12 PF03522.15 OAJ13170.1 - 0.12 11.3 3.9 0.16 10.9 3.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CTI PF06934.11 OAJ13170.1 - 0.16 10.4 2.4 0.22 10.0 2.4 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) DUF4192 PF13830.6 OAJ13170.1 - 1.3 9.0 10.8 2.4 8.1 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Erythro_esteras PF05139.14 OAJ13170.1 - 4.9 6.9 11.4 7 6.3 11.4 1.2 1 0 0 1 1 1 0 Erythromycin esterase DUF3391 PF11871.8 OAJ13170.1 - 7.6 7.1 9.9 15 6.1 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4384 PF14326.6 OAJ13172.1 - 0.041 14.0 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) Snurportin1 PF11538.8 OAJ13172.1 - 3.1 8.0 9.2 8.4 6.7 3.0 2.6 2 0 0 2 2 2 0 Snurportin1 IBN_N PF03810.19 OAJ13173.1 - 8.6e-07 28.8 0.0 3.5e-05 23.6 0.0 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAJ13173.1 - 0.045 13.8 0.1 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 Exportin 1-like protein Polysacc_deac_1 PF01522.21 OAJ13190.1 - 7.5e-27 93.7 0.0 1.2e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mito_carr PF00153.27 OAJ13192.1 - 2.5e-29 101.0 4.5 7.9e-15 54.6 0.2 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 OAJ13193.1 - 2.3e-17 62.6 0.0 2.5e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GTP_EFTU PF00009.27 OAJ13194.1 - 3e-45 154.2 0.1 6.3e-45 153.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ13194.1 - 8e-31 106.6 0.1 8e-31 106.6 0.1 2.9 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ13194.1 - 1.3e-07 31.9 0.1 4e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ13194.1 - 0.0029 17.7 0.1 0.018 15.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase HTH_23 PF13384.6 OAJ13207.1 - 0.014 15.2 0.1 0.014 15.2 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 OAJ13207.1 - 0.045 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF3853 PF12964.7 OAJ13207.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) TFIIE_alpha PF02002.17 OAJ13208.1 - 3.5e-08 33.3 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit OSTMP1 PF09777.9 OAJ13208.1 - 0.071 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TF_Zn_Ribbon PF08271.12 OAJ13208.1 - 0.33 10.5 2.4 0.91 9.1 2.4 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding ADK_lid PF05191.14 OAJ13208.1 - 1.2 9.2 7.4 0.22 11.6 1.9 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C3HC4_3 PF13920.6 OAJ13209.1 - 0.04 13.8 0.3 0.06 13.2 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PSD1 PF07587.11 OAJ13211.1 - 0.11 11.9 0.4 0.2 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) OrfB_Zn_ribbon PF07282.11 OAJ13226.1 - 0.00017 21.5 0.6 0.017 15.0 0.1 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Glyco_hydro_85 PF03644.13 OAJ13227.1 - 3.6e-09 36.5 0.2 7e-09 35.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 Peptidase_M15_4 PF13539.6 OAJ13229.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase BCDHK_Adom3 PF10436.9 OAJ13230.1 - 1e-05 25.4 0.2 1.6e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Fungal_trans PF04082.18 OAJ13245.1 - 6.5e-14 51.6 1.4 1.6e-13 50.3 1.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ13245.1 - 0.00014 21.9 7.7 0.00026 21.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.13 OAJ13245.1 - 0.0027 17.9 12.2 0.0027 17.9 12.2 2.5 3 0 0 3 3 3 1 YL1 nuclear protein CENP-B_dimeris PF09026.10 OAJ13245.1 - 5.5 7.4 23.3 4.4 7.8 18.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mito_carr PF00153.27 OAJ13246.1 - 7.4e-36 122.0 3.8 6.3e-13 48.5 0.2 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein EB PF01683.18 OAJ13247.1 - 5.2 7.4 77.9 3.1 8.2 8.0 7.3 3 3 5 8 8 8 0 EB module Rrn6 PF10214.9 OAJ13248.1 - 0.048 12.2 14.4 0.079 11.4 14.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Macoilin PF09726.9 OAJ13248.1 - 0.12 10.9 4.4 0.15 10.6 4.4 1.2 1 0 0 1 1 1 0 Macoilin family U79_P34 PF03064.16 OAJ13248.1 - 0.23 10.8 5.4 0.39 10.0 5.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Borrelia_P83 PF05262.11 OAJ13248.1 - 1.1 7.7 11.2 1.6 7.2 11.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CPSF100_C PF13299.6 OAJ13248.1 - 1.2 9.3 6.1 2.8 8.1 6.1 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TAF4 PF05236.14 OAJ13248.1 - 2.1 8.0 15.5 0.16 11.7 8.8 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family RR_TM4-6 PF06459.12 OAJ13248.1 - 2.6 7.8 10.2 4.5 7.0 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 OAJ13248.1 - 3.1 6.6 13.6 4.6 6.0 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Plasmodium_Vir PF05795.11 OAJ13248.1 - 3.6 6.9 5.6 0.68 9.3 2.2 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MCM_bind PF09739.9 OAJ13248.1 - 3.6 5.9 7.0 5 5.5 7.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hid1 PF12722.7 OAJ13248.1 - 9.6 4.2 6.5 12 3.9 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TPR_10 PF13374.6 OAJ13264.1 - 3e-29 100.0 35.4 0.00014 21.6 0.1 12.1 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ13264.1 - 1.1e-28 99.3 36.1 3.6e-06 27.2 2.0 11.4 6 3 5 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ13264.1 - 1.5e-10 40.4 12.3 5 7.6 0.0 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ13264.1 - 7.3e-06 25.6 11.6 0.87 9.5 0.1 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13264.1 - 1.7e-05 24.6 25.5 0.85 9.9 0.1 10.6 12 0 0 12 12 11 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OAJ13264.1 - 4.3e-05 22.9 5.1 5.3 6.6 0.1 6.6 7 0 0 7 7 7 1 SHNi-TPR ANAPC5 PF12862.7 OAJ13264.1 - 0.00093 19.2 10.6 32 4.7 0.0 7.7 4 2 1 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 OAJ13264.1 - 0.0015 19.0 5.3 0.47 11.0 0.0 5.3 6 1 0 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ13264.1 - 0.0015 18.6 4.5 2.7 8.1 0.0 5.3 2 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) Arm PF00514.23 OAJ13264.1 - 0.033 14.2 1.2 2.2 8.5 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 OAJ13264.1 - 0.096 11.4 0.2 17 4.0 0.0 3.9 4 0 0 4 4 4 0 Fungal protein kinase SeqA PF03925.13 OAJ13264.1 - 0.12 12.3 0.0 17 5.4 0.0 4.1 4 1 1 5 5 5 0 SeqA protein C-terminal domain TPR_4 PF07721.14 OAJ13264.1 - 0.64 10.8 11.7 26 5.8 0.6 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat CBP_BcsQ PF06564.12 OAJ13264.1 - 3 7.3 7.1 27 4.1 0.1 4.2 4 0 0 4 4 4 0 Cellulose biosynthesis protein BcsQ TPR_7 PF13176.6 OAJ13264.1 - 3.6 7.8 18.4 0.73 10.0 0.1 7.3 10 0 0 10 10 7 0 Tetratricopeptide repeat ENTH PF01417.20 OAJ13265.1 - 9e-44 148.5 0.1 1.2e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAJ13265.1 - 0.0025 16.9 0.2 0.0036 16.4 0.2 1.1 1 0 0 1 1 1 1 ANTH domain DUF2156 PF09924.9 OAJ13265.1 - 0.004 16.2 0.3 0.0057 15.7 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) VHS PF00790.19 OAJ13265.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain Cytochrom_B558a PF05038.13 OAJ13266.1 - 0.0044 16.6 1.2 0.21 11.1 0.4 2.8 2 0 0 2 2 2 1 Cytochrome Cytochrome b558 alpha-subunit DUF2721 PF11026.8 OAJ13266.1 - 2.6 8.0 12.1 0.72 9.8 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) LST1 PF05083.13 OAJ13266.1 - 7 7.0 5.6 2.6 8.4 0.9 2.4 2 0 0 2 2 2 0 LST-1 protein PQ-loop PF04193.14 OAJ13267.1 - 5e-31 106.3 13.0 3.4e-18 65.1 1.9 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3328 PF11807.8 OAJ13268.1 - 0.32 10.7 2.2 0.36 10.6 0.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3328) Phage_integrase PF00589.22 OAJ13281.1 - 0.018 14.8 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family LRR_8 PF13855.6 OAJ13282.1 - 0.02 14.6 0.4 0.083 12.7 0.2 2.1 2 0 0 2 2 2 0 Leucine rich repeat RVT_1 PF00078.27 OAJ13284.1 - 6.5e-27 94.5 0.0 1.2e-20 74.0 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) WES_acyltransf PF03007.16 OAJ13285.1 - 1.9e-17 63.9 0.0 3.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 OAJ13285.1 - 1.7e-08 34.5 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DSBA PF01323.20 OAJ13297.1 - 2.7e-24 86.0 0.0 3.8e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Formyl_trans_N PF00551.19 OAJ13298.1 - 4.6e-18 65.6 0.0 6.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 OAJ13298.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DKCLD PF08068.12 OAJ13299.1 - 6.2e-33 112.7 0.3 5e-32 109.8 0.6 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 OAJ13299.1 - 1.5e-23 83.8 0.2 2.7e-20 73.3 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAJ13299.1 - 5.5e-22 77.7 0.4 9.7e-22 76.9 0.4 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OAJ13299.1 - 1.4e-19 69.8 0.7 3.1e-19 68.7 0.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAJ13299.1 - 0.0037 17.5 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain SR-25 PF10500.9 OAJ13299.1 - 0.14 11.8 20.3 0.25 10.9 20.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LYRIC PF15686.5 OAJ13299.1 - 2 7.9 28.5 3 7.3 28.5 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Ima1_N PF09779.9 OAJ13300.1 - 8.6e-24 84.9 1.4 3.6e-23 82.9 0.2 2.5 2 0 0 2 2 2 1 Ima1 N-terminal domain Sporozoite_P67 PF05642.11 OAJ13300.1 - 0.029 12.5 10.1 0.044 11.9 10.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 OAJ13300.1 - 0.63 8.2 9.6 1 7.5 9.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Androgen_recep PF02166.16 OAJ13300.1 - 3.5 6.3 14.4 0.05 12.5 1.3 3.3 4 0 0 4 4 4 0 Androgen receptor MTS PF05175.14 OAJ13301.1 - 7.2e-07 28.9 0.0 0.00031 20.4 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAJ13301.1 - 0.024 15.3 0.0 0.047 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAJ13301.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Hydrolase_4 PF12146.8 OAJ13302.1 - 3.9e-39 134.3 0.1 6.3e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ13302.1 - 5.3e-12 45.9 0.5 8.1e-10 38.8 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ13302.1 - 2.5e-10 41.3 0.2 4e-10 40.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAJ13302.1 - 0.00029 20.5 0.0 0.0024 17.5 0.0 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Asp2 PF16929.5 OAJ13302.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Phage_integrase PF00589.22 OAJ13303.1 - 0.00013 21.8 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family 2_5_RNA_ligase2 PF13563.6 OAJ13320.1 - 2.7e-16 59.9 1.3 1.6e-08 34.6 0.1 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 OAJ13320.1 - 0.00012 22.2 0.2 0.25 11.5 0.0 3.0 3 0 0 3 3 3 2 LigT like Phosphoesterase Amidohydro_2 PF04909.14 OAJ13320.1 - 0.07 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Amidohydrolase HU-CCDC81_bac_2 PF18175.1 OAJ13320.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 CPDase PF07823.11 OAJ13320.1 - 0.15 11.7 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein TruB_N PF01509.18 OAJ13321.1 - 8.1e-37 126.9 0.0 9.7e-36 123.4 0.0 2.1 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAJ13321.1 - 9e-07 29.0 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF4637 PF15470.6 OAJ13321.1 - 3 7.6 8.2 0.18 11.5 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) F-box-like PF12937.7 OAJ13322.1 - 0.0002 21.2 0.5 0.00072 19.4 0.5 2.0 1 0 0 1 1 1 1 F-box-like TatD_DNase PF01026.21 OAJ13323.1 - 1.3e-19 70.6 0.3 2.6e-19 69.6 0.3 1.5 1 0 0 1 1 1 1 TatD related DNase DUF913 PF06025.12 OAJ13323.1 - 0.47 9.4 6.7 1.8 7.4 1.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Ribosomal_S13_N PF08069.12 OAJ13324.1 - 0.11 12.6 0.5 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain DIM PF08194.12 OAJ13326.1 - 0.34 11.2 1.8 0.54 10.5 1.8 1.3 1 0 0 1 1 1 0 DIM protein Nop14 PF04147.12 OAJ13327.1 - 0.096 10.9 4.9 0.12 10.6 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ13327.1 - 1.7 6.6 4.2 2.1 6.3 4.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ13327.1 - 8.2 5.6 7.0 11 5.2 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein PH PF00169.29 OAJ13345.1 - 2.8e-14 53.5 0.0 8.9e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 OAJ13345.1 - 4.1e-14 52.2 0.1 8.4e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ13345.1 - 5.1e-12 45.2 0.4 1.2e-11 44.0 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ13345.1 - 3.8e-09 36.1 0.0 8.5e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 OAJ13345.1 - 1.7e-06 28.1 0.0 3.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ13345.1 - 0.00057 20.3 0.1 0.0014 19.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 OAJ13345.1 - 0.23 11.7 0.3 0.47 10.7 0.3 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif KGG PF10685.9 OAJ13346.1 - 8.7e-09 35.4 8.1 9.6e-07 28.9 0.2 4.0 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif SAPS PF04499.15 OAJ13347.1 - 0.0011 17.8 6.3 0.0015 17.4 6.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein BUD22 PF09073.10 OAJ13347.1 - 0.0022 17.4 18.3 0.0022 17.4 18.3 2.1 3 0 0 3 3 3 1 BUD22 DUF2151 PF10221.9 OAJ13347.1 - 0.2 10.2 5.4 0.28 9.8 5.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DDHD PF02862.17 OAJ13347.1 - 0.75 9.9 6.6 0.069 13.3 1.6 1.8 2 0 0 2 2 2 0 DDHD domain Nop14 PF04147.12 OAJ13347.1 - 0.77 7.9 28.2 1 7.5 28.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4407 PF14362.6 OAJ13347.1 - 1 8.6 13.6 1.8 7.9 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPP4R2 PF09184.11 OAJ13347.1 - 1 8.9 21.2 1.9 8.0 21.2 1.4 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 OAJ13347.1 - 2 8.2 17.8 3.4 7.4 17.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 OAJ13347.1 - 2.6 6.2 22.0 4.1 5.6 22.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 OAJ13347.1 - 3.3 6.6 25.1 5.1 6.0 25.1 1.3 1 0 0 1 1 1 0 Paf1 Tim54 PF11711.8 OAJ13347.1 - 6.8 5.4 13.4 12 4.5 13.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Thioredoxin PF00085.20 OAJ13348.1 - 2.8e-35 120.4 0.0 1.3e-21 76.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OAJ13348.1 - 3.2e-10 40.2 0.0 0.0078 16.1 0.0 3.6 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OAJ13348.1 - 1.8e-05 24.7 0.0 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 OAJ13348.1 - 0.002 18.6 0.0 0.71 10.3 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ13348.1 - 0.0047 16.8 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAJ13348.1 - 0.02 15.2 0.1 0.18 12.1 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin-like Redoxin PF08534.10 OAJ13348.1 - 0.083 12.6 0.1 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 Redoxin MSA-2c PF12238.8 OAJ13348.1 - 10 6.1 8.6 18 5.3 8.6 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c KOW PF00467.29 OAJ13349.1 - 2.7e-07 30.3 18.6 0.00076 19.4 0.2 4.6 6 0 0 6 6 6 3 KOW motif CTD PF12815.7 OAJ13349.1 - 0.061 13.9 56.2 0.39 11.3 12.4 5.0 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 GrpE PF01025.19 OAJ13368.1 - 2.2e-42 144.5 0.0 3.3e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 GrpE Sel1 PF08238.12 OAJ13369.1 - 3.9e-16 59.1 19.5 7.7e-08 32.8 0.3 4.5 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 OAJ13369.1 - 4 7.8 5.8 6.7 7.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 OAJ13370.1 - 7.4e-32 111.1 0.0 1.4e-31 110.1 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 OAJ13370.1 - 4.7e-17 61.9 9.5 9.1e-17 61.0 9.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OAJ13370.1 - 2.2e-07 31.3 0.0 5.9e-05 23.5 0.0 2.7 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 OAJ13370.1 - 0.029 14.2 0.1 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Kdo PF06293.14 OAJ13371.1 - 5.3e-05 22.7 0.0 0.0026 17.1 0.0 2.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ13371.1 - 0.00024 21.1 0.0 0.017 15.1 0.0 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAJ13371.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 OAJ13371.1 - 0.016 14.5 0.0 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 OAJ13371.1 - 0.052 13.2 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family TPP1 PF10341.9 OAJ13372.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD TB2_DP1_HVA22 PF03134.19 OAJ13373.1 - 3.9e-25 87.6 6.7 3.9e-25 87.6 6.7 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DNA_topoisoIV PF00521.20 OAJ13374.1 - 1.1e-128 429.8 0.1 5.2e-128 427.6 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAJ13374.1 - 9.8e-49 164.9 0.3 3.6e-48 163.1 0.3 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAJ13374.1 - 5.7e-28 97.6 0.4 1.2e-27 96.5 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAJ13374.1 - 1.7e-12 47.8 0.0 4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAJ13374.1 - 5.4e-08 33.0 0.0 6.6e-07 29.5 0.0 2.9 3 0 0 3 3 3 1 Toprim domain Macoilin PF09726.9 OAJ13374.1 - 0.95 7.9 13.4 1.8 7.0 13.4 1.4 1 0 0 1 1 1 0 Macoilin family GEMIN8 PF15348.6 OAJ13374.1 - 2.3 8.4 6.3 6.9 6.9 6.3 1.8 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2368 PF10166.9 OAJ13386.1 - 1.4 8.6 5.0 2.8 7.5 5.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Metallophos PF00149.28 OAJ13387.1 - 1.1e-37 130.6 0.3 1.5e-37 130.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ13387.1 - 0.011 16.2 0.2 0.022 15.2 0.2 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 OAJ13387.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain HA2 PF04408.23 OAJ13389.1 - 1.2e-20 73.7 2.7 1.9e-20 73.2 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ13389.1 - 5.5e-19 68.3 0.1 1.4e-18 67.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ13389.1 - 6.2e-15 55.5 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ13389.1 - 2e-07 30.9 0.0 5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ13389.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ13389.1 - 0.00057 20.2 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ13389.1 - 0.00084 19.7 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAJ13389.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 OAJ13389.1 - 0.023 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ13389.1 - 0.08 13.3 1.3 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 OAJ13389.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAJ13389.1 - 0.17 12.4 1.0 0.54 10.8 0.1 2.3 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.6 OAJ13389.1 - 0.83 9.7 5.3 4 7.5 0.1 3.7 3 1 0 3 3 3 0 AAA domain CopD PF05425.13 OAJ13409.1 - 0.021 15.2 4.2 0.84 10.1 0.3 2.5 2 1 0 2 2 2 0 Copper resistance protein D LapA_dom PF06305.11 OAJ13409.1 - 0.45 10.4 1.4 4.8 7.1 0.5 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Tetraspanin PF00335.20 OAJ13409.1 - 1.3 8.7 5.1 0.16 11.6 0.8 1.6 2 0 0 2 2 2 0 Tetraspanin family Colicin_V PF02674.16 OAJ13409.1 - 5.8 6.9 7.9 0.23 11.4 1.0 2.1 2 1 0 2 2 2 0 Colicin V production protein PHD PF00628.29 OAJ13410.1 - 0.00082 19.2 7.8 0.00082 19.2 7.8 2.4 3 0 0 3 3 3 1 PHD-finger bZIP_1 PF00170.21 OAJ13410.1 - 0.024 14.7 0.4 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 OAJ13410.1 - 0.077 13.1 2.8 0.16 12.1 1.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-HC5HC2H PF13771.6 OAJ13410.1 - 0.15 12.3 4.8 1.8 8.9 1.3 2.9 3 0 0 3 3 3 0 PHD-like zinc-binding domain TMF_TATA_bd PF12325.8 OAJ13410.1 - 0.2 11.9 1.8 2.1 8.6 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 OAJ13410.1 - 0.5 10.7 2.7 1.1 9.7 0.1 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family zf-HC5HC2H_2 PF13832.6 OAJ13410.1 - 0.91 9.7 7.0 4.9 7.4 1.8 2.8 2 1 0 3 3 3 0 PHD-zinc-finger like domain PRIMA1 PF16101.5 OAJ13412.1 - 1 9.4 16.0 0.025 14.6 5.5 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 rve PF00665.26 OAJ13413.1 - 5.3e-07 29.9 0.0 2.5e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain PQ-loop PF04193.14 OAJ13414.1 - 6.2e-36 122.0 12.4 6.6e-18 64.2 2.7 2.5 2 0 0 2 2 2 2 PQ loop repeat Frag1 PF10277.9 OAJ13414.1 - 0.00096 18.8 5.1 0.0017 18.0 5.1 1.4 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2781 PF10914.8 OAJ13414.1 - 0.0039 17.6 1.3 0.0067 16.8 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Form-deh_trans PF09163.11 OAJ13414.1 - 0.02 14.6 0.1 0.067 13.0 0.1 1.8 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Arteri_Gl PF00951.18 OAJ13414.1 - 0.021 14.6 0.7 0.051 13.4 0.7 1.6 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Mg_trans_NIPA PF05653.14 OAJ13414.1 - 0.021 13.9 2.3 0.06 12.4 2.1 1.7 1 1 1 2 2 2 0 Magnesium transporter NIPA DUF1218 PF06749.12 OAJ13414.1 - 0.48 11.0 4.3 0.25 11.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2975 PF11188.8 OAJ13414.1 - 6.7 6.6 10.4 3.2 7.6 1.9 2.6 2 2 0 3 3 3 0 Protein of unknown function (DUF2975) tRNA_int_endo PF01974.17 OAJ13416.1 - 3.1e-18 65.6 0.1 6.2e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAJ13416.1 - 0.0025 17.5 0.7 0.0057 16.3 0.7 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DnaJ_CXXCXGXG PF00684.19 OAJ13417.1 - 0.00018 21.8 4.8 0.028 14.8 0.3 2.3 2 0 0 2 2 2 2 DnaJ central domain PEX11 PF05648.14 OAJ13427.1 - 6.8e-63 212.1 2.3 7.7e-63 211.9 2.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GPI-anchored PF10342.9 OAJ13428.1 - 8e-12 45.8 1.0 8e-12 45.8 1.0 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1206 PF06724.11 OAJ13428.1 - 0.16 12.1 5.8 3.7 7.7 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Apt1 PF10351.9 OAJ13428.1 - 0.4 9.5 8.6 0.5 9.2 8.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MGC-24 PF05283.11 OAJ13428.1 - 1.7 9.1 12.8 3.6 8.0 12.8 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hamartin PF04388.12 OAJ13428.1 - 2.8 6.5 9.5 3 6.4 9.5 1.1 1 0 0 1 1 1 0 Hamartin protein SSP160 PF06933.11 OAJ13428.1 - 4.1 5.5 29.3 8 4.5 29.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SCHIP-1 PF10148.9 OAJ13428.1 - 4.4 6.9 5.0 33 4.0 5.8 1.8 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 GREB1 PF15782.5 OAJ13428.1 - 5.1 4.1 5.6 6 3.8 5.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 OAJ13428.1 - 8.4 6.2 12.0 11 5.8 12.0 1.1 1 0 0 1 1 1 0 SPX domain Methyltransf_28 PF02636.17 OAJ13429.1 - 9.5e-36 123.8 0.0 1.7e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.10 OAJ13429.1 - 9.9e-26 90.6 10.0 1.4e-09 37.7 0.0 5.8 4 2 1 5 5 5 4 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.20 OAJ13429.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CNDH2_C PF16858.5 OAJ13429.1 - 1.3 8.8 5.6 11 5.7 0.7 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nucleo_P87 PF07267.11 OAJ13429.1 - 1.8 7.3 3.8 0.72 8.6 0.7 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 CPSF100_C PF13299.6 OAJ13430.1 - 3.7e-33 115.1 0.0 3.7e-33 115.1 0.0 2.6 4 0 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_6 PF16661.5 OAJ13430.1 - 2.7e-23 82.4 0.0 7.5e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 OAJ13430.1 - 1.9e-14 53.9 0.0 6.4e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 OAJ13430.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain RVT_1 PF00078.27 OAJ13431.1 - 2.6e-19 69.6 0.0 4.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI3_PI4_kinase PF00454.27 OAJ13443.1 - 1.6e-53 182.1 0.0 1.2e-52 179.2 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAJ13443.1 - 2.3e-31 108.9 1.2 2.3e-31 108.9 1.2 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAJ13443.1 - 2.7e-08 33.5 0.0 6.3e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 FATC domain CENP-Q PF13094.6 OAJ13443.1 - 0.32 11.2 3.8 1.6 8.9 3.8 2.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Aminotran_1_2 PF00155.21 OAJ13444.1 - 5.5e-34 117.9 0.0 6.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2408 PF10303.9 OAJ13445.1 - 5.3e-51 172.7 1.4 8.8e-36 123.5 0.0 4.7 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) CDC45 PF02724.14 OAJ13445.1 - 0.15 10.3 0.9 0.3 9.3 0.9 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF465 PF04325.13 OAJ13445.1 - 0.72 9.9 4.6 1.7 8.8 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) PBP1_TM PF14812.6 OAJ13445.1 - 1.2 9.5 6.9 2.4 8.6 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OAJ13445.1 - 6.3 4.8 9.1 11 4.0 9.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pyridoxal_deC PF00282.19 OAJ13446.1 - 9.4e-42 143.0 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DAO PF01266.24 OAJ13461.1 - 8.6e-23 81.5 0.2 6.7e-13 48.9 0.0 3.3 2 2 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ13461.1 - 0.00029 21.0 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ13461.1 - 0.00057 19.1 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 OAJ13461.1 - 0.0017 18.0 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 OAJ13461.1 - 0.0031 16.8 0.3 0.0079 15.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ13461.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAJ13461.1 - 0.014 15.0 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 OAJ13461.1 - 0.028 15.0 0.6 0.053 14.1 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OAJ13461.1 - 0.069 12.6 0.1 0.26 10.7 0.1 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 OAJ13461.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ13461.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Linker_histone PF00538.19 OAJ13462.1 - 6.1e-19 68.2 0.2 6.1e-19 68.2 0.2 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family Forkhead PF00250.18 OAJ13462.1 - 0.03 14.6 0.0 5.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Forkhead domain Peptidase_S15 PF02129.18 OAJ13462.1 - 0.1 12.2 1.2 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF349 PF03993.12 OAJ13463.1 - 7 7.0 8.8 2 8.8 4.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) MIR PF02815.19 OAJ13464.1 - 1.4e-07 31.5 0.0 5.4e-07 29.6 0.0 1.7 1 1 1 2 2 2 1 MIR domain Cu_amine_oxid PF01179.20 OAJ13465.1 - 9.9e-155 515.5 0.0 1.2e-154 515.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAJ13465.1 - 4.3e-13 49.5 0.0 9.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAJ13465.1 - 0.0097 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_1 PF00515.28 OAJ13478.1 - 1e-23 82.1 1.9 5.6e-09 35.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ13478.1 - 2.5e-18 65.5 5.5 2e-07 30.6 1.3 3.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 OAJ13478.1 - 9.2e-17 59.7 9.6 1.7e-07 30.8 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ13478.1 - 1.6e-12 46.9 0.8 2.1e-06 27.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ13478.1 - 6.5e-12 44.7 1.8 7.9e-06 25.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ13478.1 - 1.2e-08 35.1 14.3 1.3e-05 25.6 0.2 4.7 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ13478.1 - 9.6e-08 31.5 1.2 0.00028 20.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ13478.1 - 4.1e-07 30.4 2.3 0.00023 21.6 0.2 3.2 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ13478.1 - 1.7e-06 27.7 2.3 0.00065 19.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ13478.1 - 4.7e-06 27.1 9.6 0.0012 19.4 0.2 4.1 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ13478.1 - 6.1e-05 23.2 8.5 0.00014 22.0 2.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ13478.1 - 0.00029 20.9 5.5 0.00073 19.6 0.3 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 OAJ13478.1 - 0.0015 18.4 3.0 0.0015 18.4 3.0 2.7 1 1 1 2 2 2 1 STI1 domain RPN7 PF10602.9 OAJ13478.1 - 0.022 14.5 0.9 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 OAJ13478.1 - 0.15 12.8 4.9 5.5 7.8 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 OAJ13478.1 - 1.9 7.3 8.6 0.22 10.4 0.6 2.5 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Glyco_transf_20 PF00982.21 OAJ13479.1 - 3.2e-142 474.6 0.0 5.8e-142 473.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAJ13479.1 - 7.4e-22 77.6 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Cyclase_polyket PF04673.12 OAJ13479.1 - 0.12 12.7 0.4 0.29 11.4 0.4 1.6 1 0 0 1 1 1 0 Polyketide synthesis cyclase CENP-B_dimeris PF09026.10 OAJ13481.1 - 0.14 12.6 7.1 0.3 11.5 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ13481.1 - 0.57 9.4 2.5 0.89 8.8 2.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ13481.1 - 2.3 6.2 4.6 3.2 5.7 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OAJ13481.1 - 4 7.1 4.4 6.5 6.4 3.6 1.7 2 0 0 2 2 2 0 FAM176 family SnoaL_2 PF12680.7 OAJ13482.1 - 0.014 16.0 0.1 0.024 15.3 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain Transposase_21 PF02992.14 OAJ13499.1 - 0.0089 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 zf-C2H2_2 PF12756.7 OAJ13499.1 - 0.19 12.1 0.4 0.43 10.9 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Syntaxin_2 PF14523.6 OAJ13500.1 - 1 9.8 4.4 0.76 10.2 0.3 2.6 3 0 0 3 3 3 0 Syntaxin-like protein zf-BED PF02892.15 OAJ13501.1 - 0.19 11.7 0.2 0.43 10.6 0.2 1.5 1 0 0 1 1 1 0 BED zinc finger Ribosomal_S6e PF01092.19 OAJ13511.1 - 5.6e-55 184.7 0.4 9.4e-55 183.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Lipase_3 PF01764.25 OAJ13513.1 - 2.1e-12 47.1 0.0 1e-11 44.9 0.0 2.1 2 1 0 2 2 2 1 Lipase (class 3) Ribosomal_S13_N PF08069.12 OAJ13514.1 - 8e-31 105.9 0.4 1.3e-30 105.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAJ13514.1 - 1.3e-13 51.0 0.5 1.8e-13 50.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAJ13514.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Fungal_trans PF04082.18 OAJ13515.1 - 1.7e-07 30.6 6.7 0.0027 16.8 0.1 3.1 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ13515.1 - 2.6e-05 24.2 8.8 4.9e-05 23.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.13 OAJ13515.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.8 3 1 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Adap_comp_sub PF00928.21 OAJ13527.1 - 6.4e-66 222.4 0.1 8.5e-66 222.0 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAJ13527.1 - 9.5e-06 25.6 0.8 1.7e-05 24.8 0.4 1.6 1 1 1 2 2 2 1 Clathrin adaptor complex small chain MAM PF00629.23 OAJ13527.1 - 0.047 13.6 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu Erf4 PF10256.9 OAJ13528.1 - 5.7e-31 107.0 0.0 6.9e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.19 OAJ13529.1 - 2.7e-32 110.5 0.0 6.2e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAJ13529.1 - 1.6e-26 92.7 0.1 1.6e-26 92.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 OAJ13529.1 - 2.4e-05 24.3 0.1 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease AP3D1 PF06375.11 OAJ13529.1 - 0.025 14.8 5.3 0.1 12.8 4.4 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PDT PF00800.18 OAJ13529.1 - 0.5 10.2 3.3 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Prephenate dehydratase Presenilin PF01080.17 OAJ13529.1 - 0.64 8.7 3.8 0.77 8.5 3.8 1.2 1 0 0 1 1 1 0 Presenilin CDT1_C PF16679.5 OAJ13529.1 - 3.4 8.2 9.5 43 4.6 8.3 3.0 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Abhydrolase_3 PF07859.13 OAJ13530.1 - 2.4e-19 70.0 0.0 4.7e-19 69.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ13530.1 - 1.6e-07 30.6 0.0 0.0053 15.7 0.0 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase HU-HIG PF18291.1 OAJ13531.1 - 0.079 13.1 0.0 1.7 8.7 0.0 2.3 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif PTPA PF03095.15 OAJ13532.1 - 2.7e-06 27.1 0.1 2.7e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Dynactin_p62 PF05502.13 OAJ13532.1 - 0.19 10.4 0.2 0.27 10.0 0.2 1.1 1 0 0 1 1 1 0 Dynactin p62 family AA_permease PF00324.21 OAJ13544.1 - 2e-118 396.0 31.9 2.4e-118 395.8 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ13544.1 - 4.7e-35 121.2 35.7 6.6e-35 120.8 35.7 1.2 1 0 0 1 1 1 1 Amino acid permease Mlo PF03094.15 OAJ13544.1 - 2.6 6.3 4.0 3.9 5.7 4.0 1.1 1 0 0 1 1 1 0 Mlo family AhpC-TSA PF00578.21 OAJ13546.1 - 1.3e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 OAJ13546.1 - 5.9e-05 23.2 0.1 9.7e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ13546.1 - 0.00019 21.2 0.0 0.00085 19.1 0.0 1.8 2 0 0 2 2 2 1 Redoxin ANAPC4_WD40 PF12894.7 OAJ13548.1 - 4.4e-08 33.3 0.0 0.038 14.3 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ13548.1 - 5.3e-05 23.9 4.2 24 6.0 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.6 OAJ13548.1 - 0.0062 16.1 0.0 0.025 14.2 0.0 2.0 3 0 0 3 3 3 1 PQQ-like domain EamA PF00892.20 OAJ13549.1 - 1e-20 74.3 36.5 1e-12 48.4 10.8 3.6 2 2 1 3 3 3 3 EamA-like transporter family PBP_N PF17093.5 OAJ13549.1 - 0.0046 17.2 0.3 0.0046 17.2 0.3 2.6 3 0 0 3 3 3 1 Penicillin-binding protein N-terminus Nuc_sug_transp PF04142.15 OAJ13549.1 - 0.084 12.0 1.0 0.19 10.8 1.0 1.5 1 0 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.16 OAJ13549.1 - 0.13 11.6 5.4 2.8 7.2 0.6 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family Abhydrolase_1 PF00561.20 OAJ13550.1 - 3.1e-20 72.9 0.3 3.8e-17 62.8 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ13550.1 - 7.3e-13 48.5 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein HABP4_PAI-RBP1 PF04774.15 OAJ13564.1 - 4.1e-13 50.2 2.2 4.1e-13 50.2 2.2 2.5 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 OAJ13564.1 - 0.00037 21.3 2.7 0.00037 21.3 2.7 5.8 5 1 0 5 5 5 1 Stm1 Cyclin_N PF00134.23 OAJ13565.1 - 4.8e-09 36.0 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAJ13565.1 - 0.0094 16.0 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 OAJ13565.1 - 0.28 11.3 0.7 45 4.2 0.0 2.9 2 1 0 2 2 2 0 Cyclin, C-terminal domain Neuraminidase PF18413.1 OAJ13565.1 - 6.5 6.4 6.5 21 4.7 0.1 2.6 2 1 1 3 3 3 0 Neuraminidase-like domain ERAP1_C PF11838.8 OAJ13566.1 - 8.1e-74 249.0 0.1 1.2e-73 248.4 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAJ13566.1 - 4.1e-51 173.6 0.1 6.3e-51 173.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Tex_N PF09371.10 OAJ13566.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain SNF2_N PF00176.23 OAJ13567.1 - 2.8e-53 180.9 0.0 4.5e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAJ13567.1 - 3.3e-41 141.5 0.0 6.1e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 OAJ13567.1 - 3.6e-13 49.8 0.0 8.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ13567.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ13567.1 - 0.00035 20.4 0.0 0.0087 15.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAJ13567.1 - 0.0015 17.8 0.0 0.019 14.2 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 OAJ13567.1 - 0.062 13.6 0.0 20 5.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain zf-CCHC_2 PF13696.6 OAJ13567.1 - 0.96 9.3 3.9 0.49 10.3 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Cupin_4 PF08007.12 OAJ13568.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 OAJ13568.1 - 0.00078 19.1 0.2 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_8 PF13621.6 OAJ13568.1 - 0.00099 18.9 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 OAJ13568.1 - 0.0015 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Cupin PepSY_2 PF13670.6 OAJ13568.1 - 0.11 12.5 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain AraC_binding PF02311.19 OAJ13568.1 - 0.15 12.0 0.5 0.35 10.8 0.5 1.8 1 1 0 1 1 1 0 AraC-like ligand binding domain Peptidase_M1_N PF17900.1 OAJ13569.1 - 3.4e-46 157.8 2.0 1.7e-42 145.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 OAJ13569.1 - 1.1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain HPTransfase PF10090.9 OAJ13569.1 - 0.065 13.0 0.1 1.7 8.5 0.0 2.4 2 1 0 2 2 2 0 Histidine phosphotransferase C-terminal domain Ribosomal_S9 PF00380.19 OAJ13571.1 - 8.3e-31 107.0 0.3 9.5e-31 106.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S3_C PF00189.20 OAJ13572.1 - 7.4e-25 87.3 0.1 3.1e-24 85.3 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAJ13572.1 - 1.6e-08 34.2 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 KH domain HAD_2 PF13419.6 OAJ13585.1 - 5e-15 56.0 0.0 1.3e-12 48.1 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ13585.1 - 4.4e-10 40.2 0.0 1.6e-08 35.1 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ13585.1 - 0.0052 17.2 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAJ13585.1 - 0.043 13.9 0.0 9.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase POB3_N PF17292.2 OAJ13586.1 - 1.5e-23 83.1 0.0 1e-20 74.0 0.0 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 OAJ13586.1 - 6.3e-20 70.9 0.0 1.6e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OAJ13586.1 - 1.9e-19 69.8 0.1 4.7e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like FH2 PF02181.23 OAJ13587.1 - 3e-83 280.0 0.0 3.8e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PMI_typeI PF01238.21 OAJ13589.1 - 6.9e-110 367.8 0.0 2.2e-109 366.1 0.0 1.7 1 1 0 1 1 1 1 Phosphomannose isomerase type I DNA_pol_delta_4 PF04081.13 OAJ13601.1 - 9.9e-25 87.4 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cation_efflux PF01545.21 OAJ13602.1 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 Cation efflux family Transposase_20 PF02371.16 OAJ13602.1 - 0.004 17.4 0.8 0.0086 16.4 0.8 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family zf-C3HC4 PF00097.25 OAJ13603.1 - 1.1e-08 34.7 1.3 1.1e-08 34.7 1.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ13603.1 - 2e-07 30.8 1.6 2.3e-05 24.2 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ13603.1 - 2.7e-06 27.3 4.3 5.9e-06 26.2 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ13603.1 - 4.3e-05 23.3 2.9 4.3e-05 23.3 2.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ13603.1 - 7.9e-05 22.9 2.4 7.9e-05 22.9 2.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ13603.1 - 0.00046 20.3 2.3 0.00099 19.2 2.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ13603.1 - 0.0012 18.8 2.3 0.0012 18.8 2.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ13603.1 - 0.0012 18.7 4.9 0.024 14.5 3.1 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF1644 PF07800.12 OAJ13603.1 - 0.15 12.1 2.5 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-ANAPC11 PF12861.7 OAJ13603.1 - 0.24 11.5 3.8 0.36 10.9 1.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAJ13603.1 - 0.25 11.7 1.7 1.1 9.6 0.3 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Peptidase_M16 PF00675.20 OAJ13604.1 - 1.1e-49 168.2 3.9 2e-49 167.4 2.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ13604.1 - 1.2e-39 136.3 0.0 1.5e-36 126.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Fe-S_biosyn PF01521.20 OAJ13605.1 - 3.1e-05 24.1 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATP-synt_C PF00137.21 OAJ13606.1 - 1.1e-33 115.4 36.7 8.9e-22 77.2 15.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C IncD PF17628.2 OAJ13606.1 - 6.4 6.6 7.1 5.5 6.8 5.7 1.6 1 1 0 1 1 1 0 Inclusion membrane protein D BRO1 PF03097.18 OAJ13617.1 - 1.1e-19 70.6 0.0 3.2e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 BRO1-like domain ABATE PF07336.11 OAJ13617.1 - 0.89 10.2 0.0 0.89 10.2 0.0 3.6 4 1 0 4 4 4 0 Putative stress-induced transcription regulator DOR PF14839.6 OAJ13618.1 - 0.15 12.0 8.5 0.074 13.0 1.2 2.6 2 1 0 2 2 2 0 DOR family Redoxin PF08534.10 OAJ13620.1 - 2e-06 27.6 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ13620.1 - 2.6e-05 24.1 0.0 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family FKBP_C PF00254.28 OAJ13621.1 - 5.3e-28 97.2 0.0 1.1e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OAJ13621.1 - 5.2e-07 30.2 0.0 5.2e-07 30.2 0.0 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain ECM1 PF05782.11 OAJ13621.1 - 0.23 10.3 2.0 0.33 9.8 2.0 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) CC190 PF15768.5 OAJ13621.1 - 2.3 8.2 10.6 3.8 7.5 10.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 DPBB_1 PF03330.18 OAJ13622.1 - 3.6e-09 36.8 0.0 5.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase KH_1 PF00013.29 OAJ13623.1 - 2.9e-94 308.9 30.5 4.4e-13 48.9 0.1 15.8 16 1 0 16 16 16 11 KH domain KH_2 PF07650.17 OAJ13623.1 - 7.5e-11 41.7 24.1 0.43 10.4 0.4 9.2 9 0 0 9 9 9 6 KH domain KH_4 PF13083.6 OAJ13623.1 - 3.3e-06 26.9 19.5 0.082 12.8 0.1 8.9 7 1 2 9 9 9 2 KH domain SLS PF14611.6 OAJ13623.1 - 0.0051 16.7 9.8 25 4.6 0.2 6.0 5 1 0 6 6 6 1 Mitochondrial inner-membrane-bound regulator acVLRF1 PF18859.1 OAJ13623.1 - 0.081 13.2 2.0 0.54 10.6 0.6 3.2 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family5 PF18846.1 OAJ13623.1 - 0.095 12.9 1.4 9.7 6.4 0.0 3.7 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 5 ThrE PF06738.12 OAJ13642.1 - 7.6e-51 172.8 24.4 2.5e-50 171.1 6.7 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ13642.1 - 3e-10 40.3 10.8 3e-10 40.3 10.8 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE HSP90 PF00183.18 OAJ13643.1 - 3e-86 290.4 0.0 3.5e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Hsp90 protein Cofac_haem_bdg PF04187.13 OAJ13643.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN HBS1_N PF08938.10 OAJ13643.1 - 0.04 14.2 0.4 0.04 14.2 0.4 1.8 2 0 0 2 2 2 0 HBS1 N-terminus Ubiq-assoc PF09145.10 OAJ13643.1 - 0.064 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-associated HSP90 PF00183.18 OAJ13644.1 - 1.7e-45 155.9 0.8 2e-45 155.7 0.8 1.0 1 0 0 1 1 1 1 Hsp90 protein MvaI_BcnI PF15515.6 OAJ13644.1 - 0.0078 16.1 0.4 0.0092 15.8 0.4 1.2 1 0 0 1 1 1 1 MvaI/BcnI restriction endonuclease family LOH1CR12 PF10158.9 OAJ13644.1 - 0.037 14.0 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 Tumour suppressor protein Tyrosinase PF00264.20 OAJ13645.1 - 1.6e-34 120.1 1.8 1.6e-34 120.1 1.8 2.2 2 1 0 2 2 2 1 Common central domain of tyrosinase Med19 PF10278.9 OAJ13645.1 - 0.053 13.5 11.5 0.083 12.8 11.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_pol_Rpc4 PF05132.14 OAJ13645.1 - 0.14 12.6 13.0 0.24 11.8 13.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Afi1 PF07792.12 OAJ13645.1 - 0.2 12.2 16.7 0.38 11.2 16.7 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 OAJ13645.1 - 0.57 10.0 19.7 0.79 9.5 19.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 OAJ13645.1 - 0.63 10.2 4.3 1.1 9.4 4.3 1.4 1 0 0 1 1 1 0 DDHD domain Cellulose_synt PF03552.14 OAJ13645.1 - 0.94 7.9 2.4 1.4 7.4 2.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Mpp10 PF04006.12 OAJ13645.1 - 1 7.7 33.1 1.3 7.4 33.1 1.1 1 0 0 1 1 1 0 Mpp10 protein CPSF100_C PF13299.6 OAJ13645.1 - 1.2 9.3 13.0 2.3 8.4 13.0 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 OAJ13645.1 - 1.2 7.4 2.5 1.7 6.9 2.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nop14 PF04147.12 OAJ13645.1 - 1.3 7.1 34.1 1.7 6.8 34.1 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 OAJ13645.1 - 2.1 7.0 11.4 2.6 6.7 11.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Astro_capsid_p PF12226.8 OAJ13645.1 - 2.1 7.4 29.4 3.4 6.7 29.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BORG_CEP PF14957.6 OAJ13645.1 - 3 9.0 10.8 5.5 8.2 10.8 1.4 1 0 0 1 1 1 0 Cdc42 effector V_ATPase_I PF01496.19 OAJ13645.1 - 5.3 4.8 16.7 7.3 4.4 16.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIP PF07454.11 OAJ13645.1 - 6.3 6.2 19.1 12 5.3 19.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HSP90 PF00183.18 OAJ13646.1 - 3e-86 290.4 0.0 3.5e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Hsp90 protein Cofac_haem_bdg PF04187.13 OAJ13646.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN HBS1_N PF08938.10 OAJ13646.1 - 0.04 14.2 0.4 0.04 14.2 0.4 1.8 2 0 0 2 2 2 0 HBS1 N-terminus Ubiq-assoc PF09145.10 OAJ13646.1 - 0.064 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-associated ThrE PF06738.12 OAJ13647.1 - 7.6e-51 172.8 24.4 2.5e-50 171.1 6.7 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ13647.1 - 3e-10 40.3 10.8 3e-10 40.3 10.8 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE TPR_12 PF13424.6 OAJ13663.1 - 2.1e-10 40.8 15.7 0.016 15.5 1.8 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13663.1 - 1.2e-08 34.4 6.9 0.86 9.9 0.5 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ13663.1 - 0.00027 20.4 6.1 0.0028 17.1 0.0 3.7 3 1 1 4 4 4 1 MalT-like TPR region TPR_14 PF13428.6 OAJ13663.1 - 0.00047 20.8 23.9 2.2 9.3 0.0 9.0 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ13663.1 - 0.0012 18.6 1.9 6.3 6.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ13663.1 - 0.0014 18.5 2.9 1.9 8.7 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ13663.1 - 0.0021 18.1 1.0 0.016 15.3 0.2 2.7 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 OAJ13663.1 - 0.0039 17.8 15.2 3.3 8.4 2.3 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ13663.1 - 0.019 14.8 12.2 21 5.2 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ13663.1 - 0.023 15.2 12.0 1.1 9.8 1.7 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ13663.1 - 0.12 13.0 10.8 0.7 10.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SF3b1 PF08920.10 OAJ13664.1 - 8.1e-27 94.1 4.5 1.5e-26 93.2 2.6 2.9 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 OAJ13664.1 - 5e-14 52.4 7.1 0.0094 16.4 0.0 8.3 7 2 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 OAJ13664.1 - 2.4e-10 40.7 11.3 0.00092 19.6 0.2 8.3 4 2 4 8 8 8 2 HEAT repeats Adaptin_N PF01602.20 OAJ13664.1 - 9e-08 31.1 0.6 0.00062 18.4 0.0 3.0 1 1 1 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 OAJ13664.1 - 1.1e-07 31.9 1.4 0.0042 17.0 0.1 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) NUC173 PF08161.12 OAJ13664.1 - 3.7e-06 26.7 1.1 0.4 10.3 0.0 4.7 3 2 2 6 6 6 2 NUC173 domain HEAT PF02985.22 OAJ13664.1 - 7.1e-06 25.8 11.2 2.8 8.4 0.1 9.0 10 0 0 10 10 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 OAJ13664.1 - 1.2e-05 25.8 0.5 1.7 9.3 0.0 5.4 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ13664.1 - 3.8e-05 23.8 1.7 18 5.4 0.0 5.8 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OAJ13664.1 - 7.5e-05 22.4 0.6 0.29 10.7 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.8 OAJ13664.1 - 0.00093 18.4 0.0 2 7.4 0.0 3.8 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 OAJ13664.1 - 0.0011 18.2 1.0 0.026 13.6 0.0 3.0 3 0 0 3 3 3 1 Dopey, N-terminal UME PF08064.13 OAJ13664.1 - 0.011 15.6 0.0 4.1 7.4 0.0 4.5 4 1 1 5 5 5 0 UME (NUC010) domain LIDHydrolase PF10230.9 OAJ13664.1 - 0.012 15.1 0.2 0.041 13.4 0.1 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DNA_pol_phi PF04931.13 OAJ13664.1 - 0.12 10.5 0.2 7 4.6 0.1 2.3 1 1 1 2 2 2 0 DNA polymerase phi RCDG1 PF15725.5 OAJ13665.1 - 0.03 14.7 0.8 0.042 14.3 0.8 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein BAR_3_WASP_bdg PF10456.9 OAJ13665.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein NAD_binding_9 PF13454.6 OAJ13666.1 - 0.021 14.8 0.8 0.032 14.2 0.8 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Med9 PF07544.13 OAJ13666.1 - 0.036 14.2 0.8 5.3 7.2 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AKNA PF12443.8 OAJ13666.1 - 0.071 13.8 0.3 0.12 13.0 0.3 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor Tox-ODYAM1 PF15642.6 OAJ13666.1 - 0.37 9.7 2.3 0.46 9.4 2.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spc7 PF08317.11 OAJ13666.1 - 0.42 9.4 4.0 0.48 9.3 4.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ubiquitin PF00240.23 OAJ13667.1 - 3.8e-30 103.5 0.1 2.9e-11 42.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ13667.1 - 7.6e-13 48.1 0.3 5.3e-06 26.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ13667.1 - 0.0051 17.2 0.2 13 6.4 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin-like domain DDE_Tnp_1_6 PF13751.6 OAJ13667.1 - 0.023 14.9 0.0 6.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain DUF4634 PF15465.6 OAJ13667.1 - 0.043 14.1 0.5 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) ADK_lid PF05191.14 OAJ13681.1 - 0.02 14.8 2.9 0.059 13.4 2.9 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid RNA_pol_3_Rpc31 PF11705.8 OAJ13682.1 - 0.03 14.6 1.9 0.03 14.6 1.9 2.7 2 1 1 3 3 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 OAJ13682.1 - 0.085 12.6 6.4 0.13 12.0 0.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 OAJ13682.1 - 0.21 11.3 17.9 0.52 10.0 2.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 OAJ13682.1 - 0.3 10.7 8.3 0.76 9.4 0.5 2.5 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 OAJ13682.1 - 0.57 10.4 16.5 3 8.1 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PPP4R2 PF09184.11 OAJ13682.1 - 0.69 9.5 8.9 3.2 7.3 0.7 2.2 2 0 0 2 2 2 0 PPP4R2 CENP-B_dimeris PF09026.10 OAJ13682.1 - 1.2 9.6 32.5 0.1 13.0 6.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ13682.1 - 1.2 8.4 22.8 0.69 9.2 4.2 2.2 2 0 0 2 2 2 0 NOA36 protein RXT2_N PF08595.11 OAJ13682.1 - 1.6 8.8 12.1 1.7 8.6 0.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal WRNPLPNID PF15017.6 OAJ13682.1 - 3.9 8.4 19.2 2.8 8.9 3.8 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box FYDLN_acid PF09538.10 OAJ13682.1 - 4.6 8.0 22.3 2.1 9.0 5.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 OAJ13682.1 - 5.6 4.9 21.2 0.25 9.4 2.8 2.0 2 0 0 2 2 2 0 DNA polymerase phi Voldacs PF03517.13 OAJ13682.1 - 7 6.8 10.5 6.8 6.8 2.2 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling SDA1 PF05285.12 OAJ13682.1 - 8.5 5.7 14.9 1.6 8.1 1.0 2.2 2 0 0 2 2 2 0 SDA1 ANAPC15 PF15243.6 OAJ13682.1 - 9.6 6.7 21.0 3.3 8.2 4.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 AAA_2 PF07724.14 OAJ13683.1 - 7.3e-46 156.4 0.0 6.8e-44 150.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAJ13683.1 - 4.7e-30 103.6 2.3 4.7e-30 103.6 2.3 3.8 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 OAJ13683.1 - 2.9e-23 82.8 0.1 4.7e-12 46.5 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAJ13683.1 - 6.3e-22 77.4 0.1 2.7e-21 75.4 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAJ13683.1 - 7.3e-14 51.9 0.0 1.3e-07 31.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ13683.1 - 9.9e-12 45.6 11.7 4e-07 30.6 0.1 5.6 4 2 1 6 6 6 2 AAA ATPase domain Clp_N PF02861.20 OAJ13683.1 - 1.7e-11 44.1 2.8 1e-05 25.5 0.6 3.8 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 OAJ13683.1 - 8.9e-09 35.7 3.7 0.0095 16.2 0.0 4.9 3 2 1 4 4 3 2 AAA domain IstB_IS21 PF01695.17 OAJ13683.1 - 1.5e-07 31.4 0.1 0.03 14.0 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 OAJ13683.1 - 3.9e-06 26.7 0.0 0.0029 17.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 OAJ13683.1 - 9.8e-06 25.8 0.3 0.038 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAJ13683.1 - 2e-05 25.1 0.3 0.088 13.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 OAJ13683.1 - 3.4e-05 23.3 0.0 0.35 10.2 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein DUF815 PF05673.13 OAJ13683.1 - 5.9e-05 22.3 0.0 0.4 9.8 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAJ13683.1 - 6.6e-05 22.5 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ13683.1 - 7.9e-05 23.0 0.0 0.27 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 OAJ13683.1 - 0.0001 22.1 0.0 0.14 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OAJ13683.1 - 0.00023 21.1 6.4 0.22 11.4 0.0 5.0 5 1 0 6 6 5 1 ATPase domain predominantly from Archaea TsaE PF02367.17 OAJ13683.1 - 0.00033 20.7 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OAJ13683.1 - 0.00033 20.6 0.0 0.74 9.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 OAJ13683.1 - 0.00036 20.5 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 OAJ13683.1 - 0.00037 20.7 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 OAJ13683.1 - 0.0005 19.4 0.1 0.38 9.9 0.1 2.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 OAJ13683.1 - 0.00051 20.3 1.6 2.5 8.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 OAJ13683.1 - 0.00067 19.4 0.1 0.49 10.1 0.0 3.4 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ13683.1 - 0.00084 18.8 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAJ13683.1 - 0.0025 18.1 0.0 0.45 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 OAJ13683.1 - 0.0033 17.3 0.0 2.1 8.3 0.0 2.8 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.12 OAJ13683.1 - 0.004 16.5 0.0 1.1 8.5 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 OAJ13683.1 - 0.0041 17.6 0.4 2 9.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 OAJ13683.1 - 0.006 16.3 0.0 2.4 7.9 0.0 3.2 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.22 OAJ13683.1 - 0.0065 16.1 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 OAJ13683.1 - 0.0083 15.9 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 OAJ13683.1 - 0.011 15.6 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 OAJ13683.1 - 0.016 15.0 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cob_adeno_trans PF01923.18 OAJ13683.1 - 0.02 15.1 1.4 0.062 13.4 1.4 1.9 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_14 PF13173.6 OAJ13683.1 - 0.033 14.2 0.1 1.2 9.2 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_23 PF13476.6 OAJ13683.1 - 0.037 14.5 16.5 0.21 12.1 0.0 4.0 3 2 0 3 3 2 0 AAA domain AAA_3 PF07726.11 OAJ13683.1 - 0.08 12.8 0.0 20 5.1 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.7 OAJ13683.1 - 0.1 11.9 0.1 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 ResIII PF04851.15 OAJ13683.1 - 0.13 12.2 0.0 91 3.0 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF3443 PF11925.8 OAJ13683.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) AAA_17 PF13207.6 OAJ13683.1 - 0.42 11.0 3.9 35 4.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF4407 PF14362.6 OAJ13683.1 - 0.45 9.8 7.3 1.1 8.6 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PV-1 PF06637.11 OAJ13683.1 - 0.94 8.2 8.7 1.6 7.5 8.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CorA PF01544.18 OAJ13683.1 - 3.7 6.8 6.5 8.6 5.6 6.5 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_GP20 PF06810.11 OAJ13683.1 - 5.5 6.8 17.8 0.46 10.3 10.5 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 Aft1_HRA PF11786.8 OAJ13685.1 - 1.3e-21 76.7 21.4 1.3e-21 76.7 21.4 4.1 4 1 0 4 4 4 1 Aft1 HRA domain bZIP_1 PF00170.21 OAJ13685.1 - 4.7e-11 42.6 3.4 8.5e-11 41.8 3.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ13685.1 - 2.3e-06 27.6 5.5 5.1e-06 26.5 5.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Nop53 PF07767.11 OAJ13685.1 - 0.0015 18.0 2.4 0.0041 16.6 2.4 1.7 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 OAJ13685.1 - 0.021 13.1 2.5 0.047 12.0 2.5 1.5 1 0 0 1 1 1 0 CDC45-like protein Nnf1 PF03980.14 OAJ13685.1 - 4.7 7.6 6.0 1.2 9.5 2.1 2.1 2 0 0 2 2 2 0 Nnf1 WD40 PF00400.32 OAJ13686.1 - 1.6e-11 44.6 14.4 5.1e-06 27.1 1.2 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ13686.1 - 4e-11 43.1 0.0 0.0088 16.3 0.0 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAJ13686.1 - 1e-05 25.3 0.1 0.023 14.3 0.0 2.8 3 0 0 3 3 3 2 PQQ-like domain eIF2A PF08662.11 OAJ13686.1 - 1e-05 25.5 0.0 0.043 13.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 OAJ13686.1 - 0.045 14.3 0.0 0.78 10.3 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain Mito_fiss_reg PF05308.11 OAJ13686.1 - 0.61 10.1 4.2 0.65 10.0 2.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator TFB6 PF17110.5 OAJ13687.1 - 0.00022 21.0 1.7 2.2 8.0 0.0 3.9 3 1 0 3 3 3 2 Subunit 11 of the general transcription factor TFIIH TMEM171 PF15471.6 OAJ13687.1 - 0.59 9.1 1.4 0.99 8.3 1.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 ADH_zinc_N PF00107.26 OAJ13700.1 - 1.1e-32 112.8 0.4 2e-32 111.9 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ13700.1 - 9.5e-15 55.8 0.0 1.6e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ13700.1 - 8.8e-05 22.4 0.0 0.0003 20.6 0.0 1.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAJ13700.1 - 0.0017 17.7 0.3 0.0031 16.8 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAJ13700.1 - 0.046 13.2 0.2 0.086 12.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase HupF_HypC PF01455.18 OAJ13700.1 - 0.14 12.4 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 HupF/HypC family Ribosomal_L4 PF00573.22 OAJ13702.1 - 3.7e-61 206.2 0.0 6e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Thioredoxin_3 PF13192.6 OAJ13702.1 - 0.096 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain DUF3591 PF12157.8 OAJ13703.1 - 7.7e-171 568.6 0.1 9.9e-171 568.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 OAJ13703.1 - 1.4e-05 24.8 3.7 3.7e-05 23.5 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ13703.1 - 0.035 14.2 1.6 0.058 13.5 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle NDUF_B8 PF05821.11 OAJ13704.1 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Amidohydro_2 PF04909.14 OAJ13706.1 - 4.9e-05 23.3 0.1 0.00016 21.5 0.0 1.7 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 OAJ13706.1 - 9.2e-05 21.9 0.1 0.0004 19.8 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Formyl_trans_N PF00551.19 OAJ13731.1 - 8.3e-32 110.4 0.0 1.1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAJ13731.1 - 7.6e-07 28.8 0.0 2.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAJ13731.1 - 0.00015 21.6 0.2 0.00045 20.1 0.0 1.8 2 0 0 2 2 2 1 ACT domain MDM10 PF12519.8 OAJ13732.1 - 6.7e-86 289.0 0.0 3.7e-58 197.5 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 OAJ13732.1 - 2.6e-05 23.8 0.2 0.0002 20.9 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic porin Septin PF00735.18 OAJ13733.1 - 2.6e-108 361.6 0.0 2.6e-108 361.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAJ13733.1 - 7.4e-08 32.5 0.0 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ13733.1 - 0.00064 19.3 2.7 0.0053 16.3 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAJ13733.1 - 0.00076 19.6 4.6 0.1 12.7 0.4 3.3 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 OAJ13733.1 - 0.0022 18.2 0.7 0.01 16.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.16 OAJ13733.1 - 0.0026 17.1 0.1 0.0053 16.1 0.1 1.6 1 1 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 OAJ13733.1 - 0.0034 16.8 0.4 0.0098 15.3 0.2 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 OAJ13733.1 - 0.0049 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ13733.1 - 0.0062 16.9 0.1 0.23 11.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain IIGP PF05049.13 OAJ13733.1 - 0.0067 15.5 0.1 0.016 14.3 0.1 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.6 OAJ13733.1 - 0.0071 16.6 1.5 0.17 12.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ13733.1 - 0.0095 15.9 5.8 0.012 15.5 0.6 3.2 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OAJ13733.1 - 0.011 16.1 1.0 0.03 14.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OAJ13733.1 - 0.014 15.9 0.4 0.042 14.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Roc PF08477.13 OAJ13733.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ13733.1 - 0.028 14.1 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OAJ13733.1 - 0.037 13.8 0.3 1.4 8.7 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OAJ13733.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 OAJ13733.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.22 OAJ13733.1 - 0.17 11.5 0.7 0.57 9.8 0.0 2.2 3 0 0 3 3 3 0 Ras family AAA_18 PF13238.6 OAJ13733.1 - 0.52 10.9 4.8 0.63 10.6 0.1 3.0 2 2 1 3 3 3 0 AAA domain DUF87 PF01935.17 OAJ13733.1 - 0.54 10.3 4.7 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OAJ13733.1 - 9.4 6.7 17.2 3.7e+02 1.5 17.2 2.2 1 1 0 1 1 1 0 AAA domain TIP120 PF08623.10 OAJ13734.1 - 2.3e-55 186.9 7.5 1.1e-53 181.5 0.2 4.5 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAJ13734.1 - 3.1e-15 56.3 23.8 0.1 13.0 0.2 10.1 6 4 5 11 11 11 7 HEAT repeats HEAT PF02985.22 OAJ13734.1 - 6e-12 44.7 19.6 2.1 8.8 0.0 12.5 15 0 0 15 15 10 3 HEAT repeat HEAT_EZ PF13513.6 OAJ13734.1 - 9e-09 35.7 31.3 0.45 11.1 0.0 11.8 11 3 3 14 14 13 3 HEAT-like repeat Cnd1 PF12717.7 OAJ13734.1 - 3.5e-07 30.4 8.8 0.45 10.5 0.6 6.9 6 2 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ13734.1 - 1.6e-06 27.0 21.5 0.0013 17.4 0.7 6.5 2 2 2 5 5 5 3 Adaptin N terminal region UME PF08064.13 OAJ13734.1 - 3.6e-05 23.6 6.4 2.5 8.1 0.0 6.7 7 1 0 7 7 7 1 UME (NUC010) domain DUF3385 PF11865.8 OAJ13734.1 - 0.00044 20.2 9.3 0.18 11.7 0.3 5.5 7 0 0 7 7 6 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OAJ13734.1 - 0.00078 20.0 0.8 3.2 8.4 0.1 6.7 8 1 2 10 10 6 1 Vacuolar 14 Fab1-binding region SIL1 PF16782.5 OAJ13734.1 - 0.0009 18.5 3.3 0.44 9.7 0.6 3.3 2 1 0 3 3 3 2 Nucleotide exchange factor SIL1 RTP1_C1 PF10363.9 OAJ13734.1 - 0.0016 18.6 8.1 0.56 10.4 0.1 6.7 6 1 3 9 9 9 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 OAJ13734.1 - 0.015 14.9 0.1 6.5 6.2 0.0 4.3 4 0 0 4 4 4 0 Tti2 family Ribosomal_S6 PF01250.17 OAJ13734.1 - 0.045 14.0 1.2 0.4 11.0 0.0 3.2 3 0 0 3 3 2 0 Ribosomal protein S6 ACDC PF14733.6 OAJ13734.1 - 0.076 13.3 1.2 45 4.4 1.2 4.0 2 1 0 2 2 2 0 AP2-coincident C-terminal Cnd3 PF12719.7 OAJ13734.1 - 0.33 10.1 3.4 16 4.6 0.0 4.6 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 OAJ13734.1 - 0.45 10.4 0.0 0.45 10.4 0.0 4.1 4 1 2 6 6 4 0 Domain of unknown function (DUF3361) BTV_NS2 PF04514.12 OAJ13734.1 - 0.45 9.3 4.7 0.81 8.5 4.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FANC_SAP PF18081.1 OAJ13734.1 - 1.1 9.5 3.3 4.3 7.6 0.3 3.7 3 0 0 3 3 2 0 Fanconi anemia-associated nuclease SAP domain RRN3 PF05327.11 OAJ13734.1 - 1.4 7.4 10.6 8.1 4.9 10.6 2.2 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAJ13734.1 - 2.5 8.0 13.5 0.8 9.6 3.1 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region Octopine_DH PF02317.17 OAJ13735.1 - 0.0015 18.6 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF616 PF04765.13 OAJ13735.1 - 0.079 12.2 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) ATPase PF06745.13 OAJ13735.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiC DNA_pol_viral_C PF00336.18 OAJ13736.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.22 OAJ13737.1 - 1.7e-05 24.6 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAJ13737.1 - 0.0014 18.9 0.0 0.0044 17.3 0.0 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3752 PF12572.8 OAJ13738.1 - 2.5e-13 50.8 39.1 3.8e-12 47.0 19.2 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF3752) Macoilin PF09726.9 OAJ13738.1 - 0.88 8.0 23.7 1.3 7.4 23.7 1.3 1 0 0 1 1 1 0 Macoilin family Fungal_trans PF04082.18 OAJ13756.1 - 1e-13 50.9 0.2 2.6e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ13756.1 - 2.1e-07 30.9 9.9 3.2e-07 30.3 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3074 PF11274.8 OAJ13757.1 - 1.8e-45 155.2 0.0 2.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Shugoshin_N PF07558.11 OAJ13759.1 - 0.035 14.0 0.3 0.097 12.6 0.3 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cnn_1N PF07989.11 OAJ13759.1 - 2.2 8.5 10.0 1 9.6 1.0 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 OAJ13759.1 - 2.4 7.2 8.6 0.23 10.5 2.6 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 OAJ13759.1 - 4.8 7.2 21.1 0.8 9.7 3.0 2.8 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 rve PF00665.26 OAJ13777.1 - 1.2e-17 64.2 0.0 3.6e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ13777.1 - 5e-17 61.8 0.0 1.1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ13777.1 - 4.2e-15 55.9 0.0 9.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ13777.1 - 1.6e-14 53.8 0.2 3.5e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OAJ13777.1 - 4.4e-06 27.2 0.0 1.4e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ13777.1 - 4.8e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAJ13777.1 - 7.7e-05 22.3 0.0 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SR-25 PF10500.9 OAJ13777.1 - 0.0069 16.0 29.6 0.02 14.5 29.6 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-H2C2 PF09337.10 OAJ13777.1 - 0.088 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 OAJ13777.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain SAPS PF04499.15 OAJ13777.1 - 1.3 7.7 5.3 2 7.1 5.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4698 PF15769.5 OAJ13777.1 - 1.7 7.6 8.5 0.43 9.6 5.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4698) zf-CCHC PF00098.23 OAJ13777.1 - 2 8.6 4.1 4.3 7.6 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.14 OAJ13777.1 - 3.6 5.7 17.0 6.2 5.0 17.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 OAJ13777.1 - 4.6 5.7 31.2 8.1 4.9 31.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 OAJ13777.1 - 5.9 5.6 18.0 9.3 5.0 18.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribonuclease_3 PF00636.26 OAJ13780.1 - 1.1e-09 38.9 0.1 1.2e-09 38.7 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ13780.1 - 0.0001 22.5 0.4 0.00054 20.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease-III-like NDC10_II PF16787.5 OAJ13787.1 - 1.3e-62 211.7 0.0 2e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ13787.1 - 8.8e-18 64.4 0.3 2.1e-17 63.2 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Xpo1 PF08389.12 OAJ13787.1 - 0.035 14.2 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Exportin 1-like protein Phage_int_SAM_4 PF13495.6 OAJ13787.1 - 1.7 9.2 3.8 25 5.4 0.1 2.8 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 OAJ13787.1 - 2.4 8.5 9.0 5.3 7.4 0.1 4.5 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain Plant_tran PF04827.14 OAJ13788.1 - 0.044 13.4 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_4 PF13359.6 OAJ13788.1 - 0.054 13.2 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.27 OAJ13789.1 - 1.1e-26 93.7 0.0 1.9e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ13789.1 - 3.9e-21 75.0 0.0 7.8e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ13789.1 - 4.5e-16 59.0 0.0 1.2e-09 38.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ13789.1 - 2e-14 53.4 0.1 4e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ13789.1 - 0.004 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MULE PF10551.9 OAJ13790.1 - 2.5e-23 82.3 0.1 1.3e-22 80.0 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OAJ13790.1 - 3e-11 43.1 0.5 7.2e-11 41.9 0.5 1.5 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 OAJ13790.1 - 7.8e-08 31.6 0.0 1.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family zf-CCHC PF00098.23 OAJ13790.1 - 0.063 13.4 2.1 0.18 11.9 2.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Sec2p PF06428.11 OAJ13801.1 - 0.02 14.8 4.0 0.052 13.5 4.0 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PE PF00934.20 OAJ13801.1 - 0.021 15.1 5.4 0.25 11.7 1.9 2.9 1 1 2 3 3 3 0 PE family Apolipoprotein PF01442.18 OAJ13801.1 - 0.077 12.9 7.3 0.16 11.8 7.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DASH_Dad2 PF08654.10 OAJ13801.1 - 0.1 13.0 0.7 0.1 13.0 0.7 2.4 2 1 1 3 3 3 0 DASH complex subunit Dad2 DUF883 PF05957.13 OAJ13801.1 - 0.25 12.0 5.9 3.6 8.2 1.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3138 PF11336.8 OAJ13801.1 - 1.5 7.3 5.8 1.7 7.1 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MFS_1 PF07690.16 OAJ13802.1 - 0.00028 19.9 0.3 0.00031 19.8 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_B_C PF00032.17 OAJ13802.1 - 0.061 13.6 0.4 0.079 13.3 0.4 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD RRM_1 PF00076.22 OAJ13804.1 - 1.3e-16 60.2 0.0 6.2e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ13804.1 - 0.2 11.3 0.0 1.3 8.6 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 OAJ13805.1 - 4.7e-33 114.1 0.0 5.3e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ13805.1 - 1.9e-28 99.1 0.0 2.2e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ13805.1 - 2.4e-08 33.6 0.0 2.7e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ13805.1 - 0.00022 21.3 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ13805.1 - 0.002 17.5 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OAJ13805.1 - 0.028 14.8 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ13805.1 - 0.049 13.5 0.1 0.091 12.7 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 OAJ13805.1 - 0.099 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAJ13805.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein Aldo_ket_red PF00248.21 OAJ13806.1 - 8.9e-43 146.6 0.0 1e-41 143.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Ish1 PF10281.9 OAJ13806.1 - 0.036 14.4 0.0 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Slx4 PF09494.10 OAJ13806.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Slx4 endonuclease Aldo_ket_red PF00248.21 OAJ13807.1 - 1.7e-69 234.3 0.0 2.2e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 OAJ13824.1 - 2e-25 88.8 0.6 3.7e-25 87.9 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ13824.1 - 5.1e-21 75.0 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ13824.1 - 2.9e-08 33.4 0.1 0.0093 15.5 0.0 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OAJ13824.1 - 0.0045 16.3 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 OAJ13824.1 - 0.0059 17.7 0.0 0.017 16.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAJ13824.1 - 0.0077 15.6 0.4 0.014 14.7 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OAJ13824.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 OAJ13824.1 - 0.034 12.9 0.2 0.047 12.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ13824.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ13824.1 - 0.36 11.4 1.8 0.55 10.8 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.29 OAJ13826.1 - 8.2e-15 55.4 0.0 1e-13 51.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ13826.1 - 7.8e-08 32.7 0.0 2.8e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ13826.1 - 1.7e-07 31.8 0.3 1.7e-07 31.8 0.3 3.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_lid_10 PF17872.1 OAJ13826.1 - 1.8e-06 28.0 0.8 1.8e-06 28.0 0.8 2.3 3 0 0 3 3 3 1 AAA lid domain AAA_19 PF13245.6 OAJ13826.1 - 0.011 16.1 0.0 0.011 16.1 0.0 3.1 4 1 0 4 4 4 0 AAA domain TsaE PF02367.17 OAJ13826.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 OAJ13826.1 - 0.54 10.0 0.0 0.54 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 OAJ13826.1 - 8.5 4.5 12.1 14 3.8 12.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Sad1_UNC PF07738.13 OAJ13827.1 - 1.6e-22 79.9 0.0 4.2e-10 39.7 0.0 3.7 2 2 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF1664 PF07889.12 OAJ13827.1 - 0.047 13.7 7.5 0.74 9.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 OAJ13827.1 - 0.31 10.3 17.7 0.041 13.2 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 OAJ13827.1 - 0.5 10.5 7.5 0.28 11.4 2.9 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 OAJ13827.1 - 0.75 9.3 32.8 0.89 9.0 11.2 4.2 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 OAJ13827.1 - 0.99 8.0 10.5 2.1 6.9 10.5 1.6 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 OAJ13827.1 - 1.3 9.1 15.9 3.1 7.9 7.3 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cytochrom_B562 PF07361.11 OAJ13827.1 - 1.9 9.2 5.5 0.96 10.1 2.5 2.2 2 0 0 2 2 1 0 Cytochrome b562 Laminin_II PF06009.12 OAJ13827.1 - 2.3 8.2 14.5 1.8 8.6 5.9 2.8 1 1 1 2 2 2 0 Laminin Domain II LMBR1 PF04791.16 OAJ13827.1 - 3.2 6.5 5.1 4.9 5.9 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 OAJ13827.1 - 4.5 7.3 10.6 5.5 7.0 0.4 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 OAJ13827.1 - 4.7 6.0 22.1 1.1 8.1 6.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 OAJ13827.1 - 5.6 7.3 5.9 25 5.2 0.4 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein Filament PF00038.21 OAJ13827.1 - 8.7 5.8 22.9 2.1 7.9 3.4 2.8 2 1 0 3 3 3 0 Intermediate filament protein F-box-like PF12937.7 OAJ13828.1 - 0.00028 20.7 0.1 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like SPT2 PF08243.11 OAJ13829.1 - 1.4e-13 51.3 28.5 1.4e-13 51.3 28.5 5.7 4 2 0 4 4 4 1 SPT2 chromatin protein TFIIA PF03153.13 OAJ13830.1 - 0.34 10.9 43.3 0.35 10.8 8.3 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAJ13830.1 - 3.6 7.6 10.5 14 5.7 4.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Acatn PF13000.7 OAJ13840.1 - 1.3e-158 529.0 19.3 7e-79 265.8 12.3 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 HGWP PF03578.15 OAJ13841.1 - 0.15 11.6 0.2 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 HGWP repeat MOZ_SAS PF01853.18 OAJ13843.1 - 3.8e-80 267.8 0.0 5.4e-80 267.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ13843.1 - 2.4e-23 81.5 1.7 4.1e-23 80.7 1.7 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OAJ13843.1 - 7.1e-19 67.4 0.2 2.6e-18 65.6 0.2 2.0 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OAJ13843.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ13843.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAM176 PF14851.6 OAJ13843.1 - 0.46 10.1 17.3 0.19 11.4 8.3 3.3 3 0 0 3 3 3 0 FAM176 family Myc_N PF01056.18 OAJ13843.1 - 0.62 9.9 17.8 0.058 13.3 10.5 2.4 2 0 0 2 2 2 0 Myc amino-terminal region SR-25 PF10500.9 OAJ13844.1 - 1.6 8.3 26.1 2.7 7.6 26.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 OAJ13844.1 - 4.4 6.0 5.2 6.1 5.6 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 OAJ13845.1 - 3.9e-62 210.0 0.0 3.8e-61 206.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13845.1 - 4.1e-34 118.0 0.0 9.4e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAJ13845.1 - 7.6e-29 99.6 15.1 7.7e-16 58.0 7.4 2.9 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 OAJ13845.1 - 2.1e-20 72.3 22.8 2.1e-11 43.5 9.2 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OAJ13845.1 - 7e-08 33.1 2.1 2.1e-07 31.5 2.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 OAJ13845.1 - 3.7e-05 23.9 0.1 7.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 OAJ13845.1 - 0.00074 18.9 0.0 0.0028 17.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OAJ13845.1 - 0.031 13.9 0.5 2.1 7.9 0.1 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 OAJ13845.1 - 0.29 11.5 17.6 0.51 10.7 3.7 2.4 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 OAJ13845.1 - 1.2 9.4 8.5 0.95 9.6 2.5 2.7 2 0 0 2 2 2 0 Up-regulated During Septation DUF2937 PF11157.8 OAJ13845.1 - 3 7.5 6.9 4.7 6.9 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4407 PF14362.6 OAJ13845.1 - 3.8 6.8 8.2 11 5.2 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FYVE_2 PF02318.16 OAJ13845.1 - 5 7.4 15.8 25 5.1 6.7 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger Malate_synthase PF01274.22 OAJ13859.1 - 4.8e-202 671.9 0.0 6e-202 671.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase WD40 PF00400.32 OAJ13875.1 - 1.9e-06 28.4 13.9 0.0058 17.5 0.1 5.9 5 1 0 5 5 5 2 WD domain, G-beta repeat RWD PF05773.22 OAJ13875.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Zn_clus PF00172.18 OAJ13878.1 - 8e-05 22.7 6.3 0.00013 22.0 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.6 OAJ13878.1 - 0.13 12.2 4.4 0.32 11.0 4.4 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c EMP24_GP25L PF01105.24 OAJ13879.1 - 7.4e-44 149.9 0.0 9.9e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_S18 PF01084.20 OAJ13880.1 - 3.5e-18 65.6 0.0 5.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 SNARE PF05739.19 OAJ13881.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 SNARE domain FliJ PF02050.16 OAJ13881.1 - 0.0072 16.5 2.7 0.082 13.1 1.0 2.5 3 0 0 3 3 3 1 Flagellar FliJ protein YjcZ PF13990.6 OAJ13881.1 - 0.45 9.9 3.7 0.3 10.4 1.7 1.6 2 0 0 2 2 2 0 YjcZ-like protein SlyX PF04102.12 OAJ13881.1 - 2 9.1 10.6 0.67 10.6 2.3 3.7 3 2 1 4 4 4 0 SlyX CRAL_TRIO PF00650.20 OAJ13897.1 - 4.1e-30 104.6 0.0 5.5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAJ13897.1 - 3.9e-06 27.1 0.0 5.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ13897.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain SSF PF00474.17 OAJ13898.1 - 1.1e-20 73.9 27.4 2.1e-20 73.0 27.4 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family ASH PF15780.5 OAJ13899.1 - 6.5e-06 26.3 0.0 0.1 12.8 0.0 3.8 4 1 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OAJ13899.1 - 0.017 15.2 0.0 31 4.8 0.0 3.6 4 0 0 4 4 4 0 Flagellar-associated PapD-like DUF1090 PF06476.12 OAJ13899.1 - 0.03 14.4 2.3 0.074 13.2 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) FAM101 PF15068.6 OAJ13901.1 - 0.00091 19.2 1.5 0.0026 17.8 1.5 1.8 1 0 0 1 1 1 1 FAM101 family PDZ_5 PF17817.1 OAJ13901.1 - 0.075 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Exo84_C PF16528.5 OAJ13902.1 - 2.2e-53 181.1 0.7 3.5e-53 180.5 0.7 1.3 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAJ13902.1 - 5.5e-16 58.4 0.4 1.7e-15 56.9 0.4 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 OAJ13902.1 - 8.6e-06 25.9 0.3 2.2e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 CEP19 PF14933.6 OAJ13902.1 - 2.2 8.6 6.3 0.49 10.7 1.5 2.3 2 1 1 3 3 3 0 CEP19-like protein Mpp10 PF04006.12 OAJ13914.1 - 1.4e-78 264.9 0.0 1.9e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF3292 PF11696.8 OAJ13914.1 - 1.9 6.8 4.6 2.8 6.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TMF_TATA_bd PF12325.8 OAJ13915.1 - 0.028 14.6 0.7 0.091 13.0 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Phage_integrase PF00589.22 OAJ13916.1 - 2.6e-05 24.1 0.0 9.3e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Phage integrase family Peptidase_C1_2 PF03051.15 OAJ13917.1 - 7e-135 450.2 0.0 2.1e-133 445.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OAJ13917.1 - 8.2e-06 26.1 0.0 0.00069 19.8 0.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Hydantoinase_B PF02538.14 OAJ13933.1 - 1.2e-211 703.6 0.1 1.6e-211 703.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase PRIMA1 PF16101.5 OAJ13936.1 - 6.6 6.8 8.4 1 9.4 2.6 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Unstab_antitox PF09720.10 OAJ13953.1 - 0.03 14.4 2.2 0.11 12.5 0.5 2.7 2 0 0 2 2 2 0 Putative addiction module component Ribonuc_2-5A PF06479.12 OAJ13953.1 - 0.3 11.3 3.2 5.1 7.3 3.7 2.5 2 1 0 2 2 2 0 Ribonuclease 2-5A Spore_III_AF PF09581.10 OAJ13954.1 - 0.018 15.1 7.8 0.044 13.8 7.8 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) BAF1_ABF1 PF04684.13 OAJ13954.1 - 0.31 10.0 15.1 3.6 6.5 11.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor WWE PF02825.20 OAJ13954.1 - 2.5 8.7 10.1 6.3 7.5 10.1 1.7 1 0 0 1 1 1 0 WWE domain FliP PF00813.20 OAJ13954.1 - 3.1 7.6 11.0 29 4.5 0.0 2.4 2 0 0 2 2 2 0 FliP family CLN3 PF02487.17 OAJ13954.1 - 5.9 5.8 16.1 15 4.5 0.1 2.3 2 0 0 2 2 2 0 CLN3 protein RIFIN PF02009.16 OAJ13954.1 - 6.8 6.5 16.4 0.078 12.9 8.2 1.8 2 0 0 2 2 2 0 Rifin TMEM154 PF15102.6 OAJ13954.1 - 7.7 6.4 0.0 7.7 6.4 0.0 4.1 3 1 0 3 3 3 0 TMEM154 protein family DUF4218 PF13960.6 OAJ13956.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) AAA_5 PF07728.14 OAJ13957.1 - 1.1e-26 93.4 0.0 2.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ13957.1 - 0.0025 18.2 0.2 1.1 9.7 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ13957.1 - 0.0079 16.5 0.0 0.078 13.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain HI0933_like PF03486.14 OAJ13957.1 - 0.071 11.8 2.0 0.12 11.1 2.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Asp PF00026.23 OAJ13958.1 - 1.2e-15 57.7 0.0 2.4e-15 56.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SURF6 PF04935.12 OAJ13975.1 - 8.8e-33 113.8 49.5 8.8e-33 113.8 49.5 3.2 2 2 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 OAJ13975.1 - 8e-15 55.2 2.8 8e-15 55.2 2.8 5.2 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 BT1 PF03092.16 OAJ13975.1 - 2.1 6.5 4.8 4.1 5.5 4.8 1.4 1 0 0 1 1 1 0 BT1 family Ceramidase_alk PF04734.13 OAJ13976.1 - 9.1e-174 578.8 0.0 1.1e-172 575.2 0.0 2.2 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAJ13976.1 - 2.7e-36 125.0 0.1 5.6e-36 123.9 0.1 1.6 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Beta-lactamase PF00144.24 OAJ13977.1 - 1.5e-36 126.3 0.0 2.1e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 OAJ13978.1 - 1.2e-58 193.7 25.6 3.8e-09 37.0 0.0 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ13978.1 - 5.8e-16 58.6 0.9 0.00091 19.5 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ13978.1 - 6.8e-05 22.8 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 OAJ13978.1 - 0.00019 21.0 0.2 0.33 10.7 0.1 3.3 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature NLE PF08154.12 OAJ13978.1 - 0.00054 20.4 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 OAJ13978.1 - 0.0012 17.8 0.0 0.3 10.0 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAJ13978.1 - 0.0017 17.2 0.8 1.5 7.5 0.1 4.0 4 1 0 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.6 OAJ13978.1 - 0.0085 15.5 0.9 0.55 9.5 0.0 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OAJ13978.1 - 0.0095 14.6 3.3 19 3.7 0.0 4.3 3 2 1 4 4 4 0 Nucleoporin Nup120/160 IKI3 PF04762.12 OAJ13978.1 - 0.074 11.0 0.1 0.14 10.1 0.1 1.4 1 0 0 1 1 1 0 IKI3 family HMG_box_2 PF09011.10 OAJ13981.1 - 0.025 15.2 0.2 0.096 13.3 0.2 2.0 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.14 OAJ13982.1 - 4e-06 26.3 0.1 3.8e-05 23.1 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ13982.1 - 0.00017 21.0 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ13982.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ13982.1 - 0.0056 16.7 0.5 0.41 10.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 OAJ13982.1 - 0.019 14.1 0.3 0.035 13.2 0.3 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ13982.1 - 0.069 12.4 0.5 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 OAJ13982.1 - 0.093 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAJ13982.1 - 0.28 9.9 3.3 0.9 8.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein PHD PF00628.29 OAJ13998.1 - 0.51 10.3 13.4 0.066 13.1 9.2 1.7 2 0 0 2 2 2 0 PHD-finger Nbl1_Borealin_N PF10444.9 OAJ13999.1 - 0.0021 17.7 0.9 0.62 9.7 0.1 2.4 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal Myb_DNA-bind_3 PF12776.7 OAJ14000.1 - 0.0018 19.2 0.0 0.0022 19.0 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain NinB PF05772.12 OAJ14000.1 - 0.02 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 NinB protein RVT_1 PF00078.27 OAJ14001.1 - 5.3e-24 85.0 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ14001.1 - 1.8e-22 79.2 0.0 1.8e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ14001.1 - 9.1e-16 58.1 0.0 8.4e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ14001.1 - 7.4e-14 51.6 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ14001.1 - 1.5e-08 34.9 0.0 4e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ14001.1 - 4e-05 24.2 0.0 0.00011 22.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ14001.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.9 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ14001.1 - 0.14 12.4 0.4 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Abhydrolase_1 PF00561.20 OAJ14014.1 - 1.2e-13 51.3 0.1 2.2e-12 47.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ14014.1 - 9.9e-12 45.9 0.0 1.6e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ14014.1 - 3.4e-09 36.3 0.0 2.6e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ14014.1 - 0.00067 19.4 0.0 0.00067 19.4 0.0 2.0 2 1 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 OAJ14014.1 - 0.003 17.0 0.0 0.053 13.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ14014.1 - 0.0087 15.9 0.2 0.34 10.7 0.1 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 OAJ14014.1 - 0.035 13.6 1.9 1.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Esterase PHB depolymerase PGAP1 PF07819.13 OAJ14014.1 - 0.16 11.7 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein PepSY_TM_like_2 PF16357.5 OAJ14014.1 - 0.3 11.1 1.7 0.62 10.0 1.7 1.5 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF4407 PF14362.6 OAJ14014.1 - 6.8 5.9 14.3 0.37 10.1 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Retrotrans_gag PF03732.17 OAJ14015.1 - 8.7e-16 58.0 0.6 1.3e-15 57.5 0.6 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ14015.1 - 0.00012 21.9 1.9 0.00022 21.1 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ14015.1 - 0.16 11.8 3.8 0.33 10.8 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Lipocalin_2 PF08212.12 OAJ14016.1 - 2.4e-07 30.8 0.0 6.5e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin_2 PF08212.12 OAJ14017.1 - 4.2e-16 59.2 0.0 5.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain BP28CT PF08146.12 OAJ14018.1 - 7.6e-37 126.6 1.1 3.2e-36 124.6 1.1 2.2 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OAJ14018.1 - 1.5e-05 25.3 0.5 1.5e-05 25.3 0.5 4.1 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 Fanconi_A_N PF15865.5 OAJ14018.1 - 0.056 12.8 5.9 0.06 12.7 0.1 3.8 3 0 0 3 3 3 0 Fanconi anaemia group A protein N terminus DUF3361 PF11841.8 OAJ14018.1 - 0.088 12.7 3.2 0.25 11.3 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DUF3385 PF11865.8 OAJ14018.1 - 0.17 11.8 8.3 0.74 9.7 0.1 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) CLASP_N PF12348.8 OAJ14018.1 - 0.22 11.1 6.9 4.5 6.8 0.1 3.5 3 0 0 3 3 3 0 CLASP N terminal Leo1 PF04004.13 OAJ14019.1 - 2.4e-41 141.3 0.3 8.9e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein Ipi1_N PF12333.8 OAJ14035.1 - 1.4e-13 51.3 1.5 6.5e-13 49.1 0.0 3.1 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation CENP-B_dimeris PF09026.10 OAJ14035.1 - 0.0052 17.2 0.9 0.011 16.1 0.9 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAJ14035.1 - 0.015 15.6 1.3 0.041 14.3 1.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OAJ14035.1 - 0.09 12.4 0.9 0.19 11.4 0.9 1.5 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 OAJ14035.1 - 0.15 11.7 0.5 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 OAJ14035.1 - 5.1 5.1 10.0 8.2 4.4 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_1 PF00583.25 OAJ14036.1 - 4.2e-14 52.8 0.0 7.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ14036.1 - 1e-09 38.4 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ14036.1 - 5.1e-08 33.2 0.0 7.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ14036.1 - 1.1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OAJ14036.1 - 2e-05 24.3 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ14036.1 - 4.3e-05 23.6 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ14036.1 - 0.00021 22.0 0.0 0.00032 21.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAJ14036.1 - 0.028 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CtaG_Cox11 PF04442.14 OAJ14037.1 - 1.2e-55 187.7 0.0 1.8e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Sec3_C PF09763.9 OAJ14038.1 - 4.7e-86 289.7 0.0 3.9e-85 286.7 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAJ14038.1 - 5.6e-18 64.9 0.0 1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 OAJ14038.1 - 0.035 12.9 0.2 0.051 12.3 0.2 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family AAA PF00004.29 OAJ14055.1 - 1.1e-09 38.8 0.1 1.2e-08 35.5 0.0 2.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAJ14055.1 - 1e-06 29.0 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ14055.1 - 1.1e-05 25.8 0.0 1.4e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ14055.1 - 0.00037 20.8 0.0 0.00055 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAJ14055.1 - 0.00039 20.4 0.0 0.00087 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAJ14055.1 - 0.00074 19.1 0.1 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ14055.1 - 0.0016 18.2 0.1 0.0021 17.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ14055.1 - 0.0042 16.9 0.3 0.013 15.3 0.4 1.6 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ14055.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAJ14055.1 - 0.051 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAJ14055.1 - 0.066 13.5 0.3 0.13 12.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ14055.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAJ14055.1 - 0.12 12.0 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 OAJ14055.1 - 0.15 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 OAJ14055.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.6 1 1 1 2 2 2 0 RNA helicase AAA_7 PF12775.7 OAJ14055.1 - 0.2 11.2 0.0 0.74 9.3 0.0 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 OAJ14055.1 - 0.23 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Trypan_PARP PF05887.11 OAJ14055.1 - 0.33 10.9 7.2 0.53 10.3 7.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RVT_1 PF00078.27 OAJ14056.1 - 3.8e-23 82.2 0.0 6.4e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ14056.1 - 3.9e-15 55.7 0.0 7.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ14056.1 - 1.6e-13 50.5 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ14056.1 - 3e-11 43.6 0.0 5.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ14056.1 - 0.0069 16.7 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Strep_pep PF14404.6 OAJ14056.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species CheC PF04509.12 OAJ14056.1 - 0.19 11.7 0.1 0.39 10.7 0.1 1.5 1 0 0 1 1 1 0 CheC-like family Peptidase_C48 PF02902.19 OAJ14058.1 - 0.037 13.9 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Telomerase_RBD PF12009.8 OAJ14074.1 - 3.9e-40 137.1 0.0 9.6e-40 135.8 0.0 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OAJ14074.1 - 1.2e-08 34.8 0.0 3.1e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_A_exo1 PF01612.20 OAJ14075.1 - 2.9e-13 49.9 0.0 6.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Macoilin PF09726.9 OAJ14075.1 - 0.72 8.3 8.0 0.036 12.7 0.2 2.0 2 0 0 2 2 2 0 Macoilin family Zn_clus PF00172.18 OAJ14076.1 - 6.1e-07 29.5 11.1 1.2e-06 28.6 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP19 PF01922.17 OAJ14077.1 - 1.2e-23 83.9 0.1 2.9e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 SRP19 protein MCU PF04678.13 OAJ14077.1 - 0.49 10.5 1.2 3.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Sec10 PF07393.11 OAJ14078.1 - 1.9e-82 277.8 0.0 4.4e-78 263.4 0.0 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.7 OAJ14078.1 - 0.0055 16.6 0.4 0.021 14.7 0.4 2.1 1 0 0 1 1 1 1 F-box-like tRNA-synt_1b PF00579.25 OAJ14079.1 - 4.5e-57 193.6 0.0 1.7e-56 191.8 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAJ14079.1 - 9.7e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 OAJ14079.1 - 0.0015 18.2 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 S4 domain PhoD PF09423.10 OAJ14095.1 - 3.2e-104 348.7 3.6 4e-104 348.4 3.6 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAJ14095.1 - 6e-27 94.0 0.8 1.3e-26 93.0 0.8 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAJ14095.1 - 1.8e-08 34.9 3.5 1.8e-08 34.9 3.5 2.4 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain HNH_2 PF13391.6 OAJ14095.1 - 0.033 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease ALG11_N PF15924.5 OAJ14096.1 - 2.6e-83 279.2 0.0 4.4e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAJ14096.1 - 1.7e-14 53.7 0.0 6e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ14096.1 - 1.7e-06 28.5 0.1 9.5e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ14096.1 - 0.0039 17.2 0.6 0.01 15.8 0.6 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Forkhead PF00250.18 OAJ14097.1 - 1.6e-29 102.0 0.0 2.8e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Mito_carr PF00153.27 OAJ14098.1 - 3.4e-57 190.4 20.1 1.1e-22 79.8 0.0 4.6 4 1 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OAJ14098.1 - 6.9e-05 22.1 0.2 0.00049 19.4 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OAJ14098.1 - 0.00012 21.7 0.1 0.00065 19.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OAJ14098.1 - 0.00064 19.1 0.5 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAJ14098.1 - 0.0062 17.0 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair NOA36 PF06524.12 OAJ14098.1 - 9.4 5.5 6.0 19 4.5 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4477 PF14780.6 OAJ14099.1 - 0.063 12.9 0.2 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) FAM199X PF15814.5 OAJ14099.1 - 6 5.8 8.9 10 5.1 8.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X Abhydrolase_1 PF00561.20 OAJ14100.1 - 1.3e-13 51.2 0.0 8.2e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ14100.1 - 2.2e-11 44.8 0.0 3.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ14100.1 - 6.8e-10 38.6 0.0 5.1e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ14100.1 - 0.0012 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAJ14100.1 - 0.044 13.6 0.1 0.52 10.1 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OAJ14100.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain FSH1 PF03959.13 OAJ14100.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 OAJ14100.1 - 0.34 10.4 1.8 1.8 8.0 0.1 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase Tubulin PF00091.25 OAJ14101.1 - 6e-62 209.3 0.0 3.7e-60 203.5 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ14101.1 - 1.1e-45 154.8 0.0 1.7e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAJ14101.1 - 0.00037 20.2 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ14101.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin like FAM72 PF14976.6 OAJ14116.1 - 7.3e-21 74.8 0.3 1.8e-20 73.6 0.3 1.6 2 0 0 2 2 2 1 FAM72 protein TetR_C_23 PF17931.1 OAJ14116.1 - 1.6 8.8 5.2 3.1 7.9 5.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GST_N PF02798.20 OAJ14117.1 - 5.2e-16 58.8 0.0 1.6e-15 57.2 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ14117.1 - 2.4e-15 56.7 0.0 5.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ14117.1 - 3.2e-11 43.4 0.0 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ14117.1 - 7.9e-09 35.6 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ14117.1 - 5.8e-06 26.3 0.0 1.9e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ14117.1 - 0.0002 21.5 0.0 0.00067 19.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ14117.1 - 0.047 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAJ14117.1 - 0.095 13.5 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Asp_protease_2 PF13650.6 OAJ14118.1 - 0.22 12.2 0.6 5.5 7.7 0.1 3.1 2 1 0 2 2 2 0 Aspartyl protease DHH PF01368.20 OAJ14118.1 - 0.26 11.5 1.3 0.64 10.3 1.3 1.8 1 1 0 1 1 1 0 DHH family HATPase_c PF02518.26 OAJ14134.1 - 8.6e-29 100.3 0.1 3.4e-28 98.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ14134.1 - 6e-24 84.4 0.2 1.3e-23 83.3 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAJ14134.1 - 2.2e-23 82.6 2.3 2.8e-11 43.6 0.0 6.2 5 1 0 5 5 5 3 PAS fold HisKA PF00512.25 OAJ14134.1 - 1.6e-19 69.6 0.1 3.9e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 OAJ14134.1 - 4.7e-13 49.1 0.2 0.0072 16.3 0.0 5.7 6 1 0 6 6 6 3 PAS fold PAS_3 PF08447.12 OAJ14134.1 - 6.4e-13 48.8 1.1 1.1e-12 48.0 0.2 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAJ14134.1 - 2.9e-07 30.7 0.0 5.1e-05 23.5 0.0 3.6 4 1 0 4 4 4 1 PAS domain PAS_8 PF13188.7 OAJ14134.1 - 0.0016 18.4 0.0 27 4.9 0.0 4.3 4 0 0 4 4 4 0 PAS domain HATPase_c_3 PF13589.6 OAJ14134.1 - 0.0046 16.8 0.4 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Retrotran_gag_2 PF14223.6 OAJ14136.1 - 1.9e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ14136.1 - 0.11 12.6 2.9 0.21 11.8 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ14136.1 - 0.74 9.6 4.6 1.6 8.5 4.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Nop14 PF04147.12 OAJ14137.1 - 0.85 7.8 4.0 1 7.5 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 OAJ14137.1 - 4.1 7.1 6.4 6.1 6.5 6.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Shugoshin_N PF07558.11 OAJ14139.1 - 0.009 15.9 0.7 0.05 13.5 0.7 2.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 OAJ14139.1 - 0.045 13.6 0.5 0.045 13.6 0.5 4.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5401 PF17380.2 OAJ14139.1 - 1.1 7.3 18.1 1.9 6.5 18.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YabA PF06156.13 OAJ14139.1 - 1.4 9.6 18.0 2.7 8.7 0.0 4.6 4 1 1 5 5 5 0 Initiation control protein YabA PEHE PF15275.6 OAJ14139.1 - 1.6 9.4 5.5 3.4 8.3 0.0 3.1 2 0 0 2 2 2 0 PEHE domain SHE3 PF17078.5 OAJ14139.1 - 3.5 7.3 17.0 7.7 6.2 11.9 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 JIP_LZII PF16471.5 OAJ14139.1 - 4.2 7.6 17.8 3.5 7.9 3.5 4.9 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II CBFB_NFYA PF02045.15 OAJ14140.1 - 0.054 14.1 0.2 0.16 12.6 0.2 1.9 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Sulfate_transp PF00916.20 OAJ14178.1 - 4.2e-11 42.2 1.0 4.2e-06 25.8 0.1 2.3 2 1 0 2 2 2 2 Sulfate permease family Ribosomal_L36e PF01158.18 OAJ14179.1 - 1.9e-38 130.6 6.0 2.3e-38 130.3 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Asp PF00026.23 OAJ14180.1 - 8.5e-30 104.2 1.2 1.4e-09 37.8 0.0 3.6 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ14180.1 - 1.2e-09 38.7 3.9 6.9e-06 26.4 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal CTP_transf_1 PF01148.20 OAJ14181.1 - 8.9e-68 228.9 16.7 1e-63 215.6 11.2 2.1 2 0 0 2 2 2 2 Cytidylyltransferase family TMCO5 PF14992.6 OAJ14181.1 - 0.12 12.0 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 TMCO5 family ATP-synt_B PF00430.18 OAJ14181.1 - 3.2 7.8 7.0 7.2 6.7 7.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MULE PF10551.9 OAJ14182.1 - 1.1e-22 80.2 0.0 2.8e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ14182.1 - 8.2e-06 24.9 0.2 0.00015 20.7 0.0 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.15 OAJ14182.1 - 0.23 12.2 1.7 0.58 10.9 1.7 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain A_deamin PF02137.18 OAJ14183.1 - 3.7e-40 138.4 0.0 5.7e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Complex1_LYR_2 PF13233.6 OAJ14184.1 - 2.3e-18 66.7 0.1 3.5e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAJ14184.1 - 8.2e-10 38.6 0.1 1.5e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Asparaginase PF00710.20 OAJ14198.1 - 2.7e-57 193.4 0.0 3.1e-51 173.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAJ14198.1 - 8.7e-31 106.5 0.0 2e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 OAJ14198.1 - 1.8e-10 41.2 0.4 1.4e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ14198.1 - 4.7e-10 39.9 0.0 9.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ14198.1 - 3.6e-08 33.0 0.6 0.0005 20.3 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAJ14198.1 - 1.4e-07 31.6 0.2 0.00043 20.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ14198.1 - 0.00049 20.4 1.2 0.47 11.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat zf-CCHC PF00098.23 OAJ14199.1 - 3.3e-06 26.9 2.4 7.5e-06 25.8 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ14199.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 OAJ14199.1 - 0.66 9.8 2.1 0.65 9.8 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.14 OAJ14200.1 - 1.9e-69 234.0 0.0 2.6e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ14200.1 - 2.4e-18 66.4 0.5 3.1e-17 62.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OAJ14200.1 - 0.0048 16.6 0.4 0.043 13.6 0.4 2.5 1 1 0 1 1 1 1 Integrase core domain Arrestin_N PF00339.29 OAJ14201.1 - 0.00046 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OAJ14201.1 - 0.0036 16.5 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Glyco_hydro_cc PF11790.8 OAJ14202.1 - 4.3e-54 183.6 1.8 5.4e-54 183.3 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TMEM135_C_rich PF15982.5 OAJ14203.1 - 0.00047 20.8 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 SNARE_assoc PF09335.11 OAJ14221.1 - 5.3e-16 59.2 4.3 5.3e-16 59.2 4.3 2.9 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 OAJ14221.1 - 0.75 10.1 9.8 0.81 10.0 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Ribosomal_L13 PF00572.18 OAJ14223.1 - 2.7e-53 179.5 1.2 3.5e-53 179.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SH3_9 PF14604.6 OAJ14224.1 - 6.4e-22 77.2 0.7 2e-13 50.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAJ14224.1 - 1.3e-19 69.6 0.0 2.7e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OAJ14224.1 - 5.2e-15 54.9 0.1 1.1e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 OAJ14224.1 - 2.1e-13 50.4 0.0 1.1e-12 48.1 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 OAJ14224.1 - 3.4e-12 46.1 5.1 5.2e-12 45.5 5.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 OAJ14224.1 - 0.012 15.9 0.2 0.012 15.9 0.2 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain JTB PF05439.12 OAJ14224.1 - 0.24 11.5 0.8 0.59 10.2 0.8 1.6 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) TetR_C_24 PF17932.1 OAJ14224.1 - 0.31 11.3 2.3 1.7 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Presenilin PF01080.17 OAJ14225.1 - 0.066 12.0 0.8 0.097 11.4 0.8 1.3 1 0 0 1 1 1 0 Presenilin PDGLE PF13190.6 OAJ14225.1 - 0.14 12.0 2.5 0.18 11.7 0.2 2.4 3 0 0 3 3 3 0 PDGLE domain Endomucin PF07010.12 OAJ14225.1 - 2.4 8.1 39.4 0.15 12.0 33.8 1.7 2 0 0 2 2 2 0 Endomucin Methyltransf_17 PF12692.7 OAJ14227.1 - 0.00083 19.4 0.2 0.0096 15.9 0.1 2.5 2 1 1 3 3 3 1 S-adenosyl-L-methionine methyltransferase Baculo_PEP_C PF04513.12 OAJ14227.1 - 0.054 13.5 0.4 7.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PadR PF03551.14 OAJ14227.1 - 0.054 13.5 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Clp1 PF06807.14 OAJ14227.1 - 0.14 12.6 0.1 0.59 10.6 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 DUF4542 PF15075.6 OAJ14228.1 - 0.052 13.9 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) Ndc1_Nup PF09531.10 OAJ14246.1 - 1.8e-23 83.1 22.8 1.5e-14 53.6 4.2 4.1 3 1 0 3 3 3 2 Nucleoporin protein Ndc1-Nup DUF4615 PF15393.6 OAJ14249.1 - 0.094 13.3 0.4 0.13 12.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) GFP PF01353.22 OAJ14249.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Green fluorescent protein MFS_1 PF07690.16 OAJ14250.1 - 7e-43 146.9 57.9 1.8e-42 145.6 51.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAJ14250.1 - 8.5e-18 64.1 13.4 8.5e-18 64.1 13.4 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ14250.1 - 3e-14 52.7 3.8 3e-14 52.7 3.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAJ14250.1 - 2.9 6.1 16.9 0.0062 14.9 4.1 2.6 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PDR_CDR PF06422.12 OAJ14251.1 - 0.0096 15.8 0.0 0.0098 15.8 0.0 1.0 1 0 0 1 1 1 1 CDR ABC transporter SurE PF01975.17 OAJ14252.1 - 2.8e-15 56.6 0.3 2.8e-15 56.6 0.3 2.1 1 1 1 2 2 2 2 Survival protein SurE SNase PF00565.17 OAJ14272.1 - 5.6e-21 75.0 2.4 2.4e-19 69.8 1.0 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue CBM_21 PF03370.13 OAJ14273.1 - 2.4e-30 105.0 0.1 3.9e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAJ14273.1 - 3.2e-08 34.1 0.2 9.1e-08 32.6 0.2 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) 2Fe-2S_thioredx PF01257.19 OAJ14274.1 - 4.5e-59 198.5 0.1 5.8e-59 198.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HLH PF00010.26 OAJ14289.1 - 2.5e-06 27.3 0.0 6.3e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.12 OAJ14289.1 - 0.4 8.8 18.5 0.25 9.5 4.9 2.2 2 0 0 2 2 2 0 Nop14-like family Prothymosin PF03247.14 OAJ14289.1 - 0.5 10.9 27.3 0.25 11.8 9.1 2.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family NOA36 PF06524.12 OAJ14289.1 - 5.7 6.2 26.6 1.7 7.9 7.6 2.4 2 0 0 2 2 2 0 NOA36 protein RRM_1 PF00076.22 OAJ14290.1 - 1.3e-23 82.6 0.0 1.3e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 OAJ14290.1 - 3.6e-17 61.0 0.0 0.00035 20.1 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 OAJ14290.1 - 0.0013 18.6 0.0 0.66 9.9 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 OAJ14290.1 - 0.083 12.4 0.6 0.47 9.9 0.0 2.4 3 0 0 3 3 3 0 RNA-recognition motif tRNA-synt_1g PF09334.11 OAJ14291.1 - 1e-75 255.0 0.9 1.3e-61 208.6 0.1 4.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAJ14291.1 - 3.1e-12 45.5 0.0 4.9e-05 21.8 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OAJ14291.1 - 3.6e-06 26.5 0.4 0.023 14.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Acyl-CoA_dh_C PF12806.7 OAJ14291.1 - 0.026 14.7 0.9 0.059 13.5 0.9 1.5 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like MT0933_antitox PF14013.6 OAJ14291.1 - 0.21 11.9 0.2 0.67 10.3 0.0 1.9 2 0 0 2 2 2 0 MT0933-like antitoxin protein FAM70 PF14967.6 OAJ14291.1 - 6 6.2 5.5 14 5.0 5.5 1.6 1 0 0 1 1 1 0 FAM70 protein Pkinase PF00069.25 OAJ14317.1 - 8.9e-66 221.9 0.0 2.2e-65 220.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14317.1 - 4.9e-35 121.1 0.0 2.6e-34 118.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAJ14317.1 - 3.8e-10 39.4 0.1 6.8e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OAJ14317.1 - 7.4e-08 32.1 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ14317.1 - 0.0055 15.7 0.3 0.01 14.8 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ14317.1 - 0.023 14.7 0.1 0.055 13.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ14317.1 - 1.1 7.9 6.3 4.3 6.0 6.3 1.9 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OAJ14317.1 - 2.1 7.9 4.8 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 RIO1 family DDE_1 PF03184.19 OAJ14318.1 - 7.6e-19 68.0 0.0 1.9e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ14318.1 - 1e-08 35.1 0.0 4.6e-08 33.0 0.0 2.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAJ14318.1 - 0.0062 16.3 0.5 0.037 13.8 0.0 2.5 3 0 0 3 3 3 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 OAJ14318.1 - 0.13 12.5 2.0 0.52 10.6 0.1 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Mg_trans_NIPA PF05653.14 OAJ14319.1 - 3.5e-61 206.9 0.3 1.3e-56 191.9 0.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OAJ14319.1 - 0.0012 19.0 0.6 0.0012 19.0 0.6 3.0 3 1 0 3 3 3 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 OAJ14319.1 - 0.025 14.5 4.3 0.063 13.2 4.3 1.7 1 0 0 1 1 1 0 7TM diverse intracellular signalling HBS1_N PF08938.10 OAJ14320.1 - 0.05 13.9 0.3 0.085 13.2 0.2 1.6 1 1 0 1 1 1 0 HBS1 N-terminus P22_AR_C PF10548.9 OAJ14320.1 - 0.068 13.3 0.3 0.12 12.5 0.2 1.5 2 0 0 2 2 2 0 P22AR C-terminal domain CLZ PF16526.5 OAJ14320.1 - 0.068 13.5 0.7 0.64 10.4 0.1 2.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cyclin_N PF00134.23 OAJ14321.1 - 1.8e-36 124.7 0.1 4.9e-36 123.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ14321.1 - 3.8e-11 43.1 0.5 1.2e-10 41.6 0.5 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain NOA36 PF06524.12 OAJ14321.1 - 0.35 10.1 4.3 0.53 9.6 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ14321.1 - 1.1 7.3 7.1 1 7.3 5.2 1.8 2 0 0 2 2 2 0 DNA polymerase phi SPT2 PF08243.11 OAJ14321.1 - 1.7 9.2 8.0 4.8 7.8 8.0 1.7 1 0 0 1 1 1 0 SPT2 chromatin protein Raftlin PF15250.6 OAJ14321.1 - 9.8 4.8 11.5 0.085 11.6 0.8 2.1 2 0 0 2 2 2 0 Raftlin Thymidylat_synt PF00303.19 OAJ14322.1 - 3.6e-25 88.6 0.0 3.9e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Sedlin_N PF04628.13 OAJ14340.1 - 3.2e-19 69.3 0.0 1.1e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Adeno_PIX PF03955.14 OAJ14340.1 - 0.069 13.3 8.0 0.1 12.7 0.5 2.9 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) Aconitase PF00330.20 OAJ14341.1 - 1.1e-111 374.1 0.0 1.1e-110 370.8 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ14341.1 - 3.2e-21 76.0 0.0 1e-20 74.4 0.0 1.8 1 1 1 2 2 2 1 Aconitase C-terminal domain SKG6 PF08693.10 OAJ14342.1 - 2.2e-10 39.8 1.6 2.2e-10 39.8 1.6 2.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAJ14342.1 - 0.0006 19.7 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family SARAF PF06682.12 OAJ14342.1 - 0.0025 17.6 4.2 0.0025 17.6 4.2 3.4 3 1 0 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis Adeno_E3_CR2 PF02439.15 OAJ14342.1 - 0.012 15.4 1.1 0.03 14.1 1.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 OAJ14342.1 - 0.033 14.1 0.4 0.063 13.2 0.0 1.5 2 0 0 2 2 2 0 Rifin CD99L2 PF12301.8 OAJ14342.1 - 0.036 14.4 0.2 0.036 14.4 0.2 3.0 2 1 0 2 2 2 0 CD99 antigen like protein 2 DUF4448 PF14610.6 OAJ14342.1 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2627 PF11118.8 OAJ14342.1 - 0.074 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) ELO PF01151.18 OAJ14343.1 - 3.4e-55 187.3 10.1 4.3e-55 186.9 10.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Zn_clus PF00172.18 OAJ14346.1 - 0.00012 22.1 15.3 0.00023 21.2 15.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3_PI4_kinase PF00454.27 OAJ14361.1 - 8e-51 173.2 0.0 1.5e-50 172.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAJ14361.1 - 1.5e-32 113.1 0.0 3.7e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.13 OAJ14361.1 - 1e-19 70.4 0.0 4.8e-19 68.2 0.0 2.4 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 OAJ14361.1 - 1.6e-07 31.0 0.0 6.5e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 FATC domain DUF241 PF03087.14 OAJ14361.1 - 0.007 16.2 2.5 0.22 11.3 0.2 3.4 3 0 0 3 3 3 1 Arabidopsis protein of unknown function DUF3385 PF11865.8 OAJ14361.1 - 0.018 14.9 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 OAJ14361.1 - 0.1 13.1 9.0 1.3 9.6 2.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat DRMBL PF07522.14 OAJ14362.1 - 4.4e-27 94.5 0.0 9.4e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 OAJ14362.1 - 0.0052 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-C2HC_2 PF13913.6 OAJ14362.1 - 0.011 15.6 4.6 0.023 14.6 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CcdB PF01845.17 OAJ14362.1 - 0.029 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 CcdB protein Lactamase_B_2 PF12706.7 OAJ14362.1 - 0.035 13.6 0.0 0.28 10.7 0.0 2.4 3 0 0 3 3 3 0 Beta-lactamase superfamily domain UvrD_C_2 PF13538.6 OAJ14363.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain XFP_N PF09364.10 OAJ14364.1 - 3.4e-122 407.8 0.5 1.6e-101 339.8 0.1 2.2 2 0 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.10 OAJ14364.1 - 6.1e-66 221.7 0.0 1.4e-64 217.3 0.0 2.2 1 1 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAJ14364.1 - 1.3e-57 194.4 0.0 2.3e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 OAJ14364.1 - 0.011 15.5 0.3 0.026 14.3 0.3 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 OAJ14364.1 - 0.12 12.0 0.1 0.78 9.4 0.1 2.4 2 1 0 2 2 2 0 Transketolase, pyrimidine binding domain Cwf_Cwc_15 PF04889.12 OAJ14383.1 - 0.39 10.4 2.8 0.8 9.4 2.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RP-C_C PF11800.8 OAJ14384.1 - 6.9 6.7 7.6 0.95 9.5 0.0 3.0 4 0 0 4 4 4 0 Replication protein C C-terminal region RNase_P_pop3 PF08228.11 OAJ14385.1 - 0.0027 17.8 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 2 RNase P subunit Pop3 Asp_Glu_race PF01177.22 OAJ14386.1 - 9.9e-08 32.1 0.1 4.9e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 OAJ14386.1 - 0.094 12.1 0.1 0.18 11.2 0.1 1.4 1 1 0 1 1 1 0 AroM protein eIF2_C PF09173.11 OAJ14387.1 - 7e-37 125.6 0.5 1.8e-36 124.2 0.5 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAJ14387.1 - 3.8e-22 78.8 0.6 5.4e-21 75.0 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAJ14387.1 - 8e-12 45.4 1.6 1.1e-11 44.9 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OAJ14387.1 - 0.0004 20.3 0.2 0.0048 16.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OAJ14387.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OAJ14387.1 - 0.02 14.9 0.9 0.081 13.0 0.1 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MFS_1 PF07690.16 OAJ14400.1 - 4.4e-42 144.3 26.2 4.9e-39 134.3 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ14400.1 - 7.6e-08 31.6 20.1 2.2e-06 26.8 20.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ14400.1 - 0.00038 19.0 3.7 0.00062 18.3 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.12 OAJ14400.1 - 0.0078 15.9 1.6 0.73 9.5 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF697) MCM PF00493.23 OAJ14401.1 - 1.6e-102 341.4 0.3 2.9e-102 340.5 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ14401.1 - 1.1e-37 128.6 1.0 2.2e-37 127.7 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAJ14401.1 - 2.9e-28 98.3 2.8 7.5e-28 96.9 2.8 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAJ14401.1 - 6.7e-26 90.5 3.0 1.9e-25 89.1 0.8 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ14401.1 - 1.9e-21 76.6 1.8 3.4e-21 75.8 0.4 2.3 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ14401.1 - 8e-08 31.9 0.0 7.4e-07 28.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAJ14401.1 - 0.0013 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAJ14401.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ14401.1 - 0.0021 18.1 0.0 0.0066 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Succ_DH_flav_C PF02910.20 OAJ14401.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Tir_receptor_M PF03549.14 OAJ14401.1 - 0.033 14.5 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain MMR_HSR1 PF01926.23 OAJ14402.1 - 3.9e-16 59.1 0.1 1.1e-14 54.5 0.0 3.1 4 0 0 4 4 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ14402.1 - 1.9e-06 27.5 0.0 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ14402.1 - 1.1e-05 25.4 0.1 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OAJ14402.1 - 0.0013 18.1 0.0 0.0048 16.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family SDA1 PF05285.12 OAJ14402.1 - 0.0042 16.6 13.5 0.0059 16.1 13.5 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OAJ14402.1 - 0.0079 14.5 10.5 0.011 14.1 10.5 1.1 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 OAJ14402.1 - 0.0096 16.2 16.2 0.02 15.1 16.2 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.12 OAJ14402.1 - 0.016 13.7 16.8 0.023 13.2 16.8 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 OAJ14402.1 - 0.099 12.0 14.9 0.15 11.4 14.9 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 OAJ14402.1 - 0.17 11.3 18.8 0.29 10.5 18.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dynamin_N PF00350.23 OAJ14402.1 - 0.21 11.6 6.3 0.21 11.6 0.6 3.0 3 1 1 4 4 4 0 Dynamin family MscS_TM PF12794.7 OAJ14402.1 - 0.42 9.4 4.5 0.66 8.8 4.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nop14 PF04147.12 OAJ14402.1 - 0.66 8.1 22.3 0.9 7.7 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 OAJ14402.1 - 0.8 9.5 15.8 1.8 8.3 15.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 OAJ14402.1 - 1.1 9.2 7.2 2.5 8.0 7.2 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_16 PF13191.6 OAJ14402.1 - 1.3 9.4 7.7 10 6.5 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain Cwf_Cwc_15 PF04889.12 OAJ14402.1 - 2.5 7.8 19.0 4.4 7.0 19.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 OAJ14402.1 - 4.5 6.0 7.7 5.9 5.5 7.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 OAJ14402.1 - 5.4 5.9 5.3 8.9 5.2 5.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MRNIP PF15749.5 OAJ14402.1 - 7.6 7.3 5.9 18 6.1 5.9 1.7 1 0 0 1 1 1 0 MRN-interacting protein AAA PF00004.29 OAJ14403.1 - 1.4e-90 300.6 0.0 4.5e-46 156.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ14403.1 - 7.3e-22 76.9 5.7 1.4e-10 40.8 1.6 2.8 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 OAJ14403.1 - 6.2e-14 52.0 0.0 2.2e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ14403.1 - 2.1e-11 44.5 5.5 0.0017 18.8 0.0 5.0 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAJ14403.1 - 4.2e-11 43.3 0.8 0.014 15.6 0.0 4.9 2 2 1 3 3 2 2 AAA domain AAA_2 PF07724.14 OAJ14403.1 - 8.6e-11 42.2 0.0 0.00024 21.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAJ14403.1 - 1.1e-10 41.7 0.3 0.00081 19.4 0.1 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAJ14403.1 - 1.7e-09 37.4 0.0 2.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 OAJ14403.1 - 1.7e-08 34.7 0.0 0.0065 16.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 OAJ14403.1 - 4.1e-07 29.6 2.0 0.02 14.2 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAJ14403.1 - 4.4e-07 30.0 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAJ14403.1 - 7.1e-07 29.6 0.0 0.057 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAJ14403.1 - 1.3e-06 28.3 0.0 0.037 13.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 OAJ14403.1 - 1.3e-06 28.7 0.0 0.034 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OAJ14403.1 - 2.7e-06 27.4 0.9 0.037 13.9 0.1 3.7 3 1 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 OAJ14403.1 - 5.1e-06 27.0 0.0 0.092 13.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter TsaE PF02367.17 OAJ14403.1 - 9.8e-06 25.6 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAJ14403.1 - 1.5e-05 25.5 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAJ14403.1 - 4.1e-05 23.2 1.9 1.2 8.7 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_3 PF07726.11 OAJ14403.1 - 5.7e-05 23.0 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ14403.1 - 9.6e-05 22.1 0.1 0.49 10.1 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain Rad17 PF03215.15 OAJ14403.1 - 0.00011 22.2 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain ATPase PF06745.13 OAJ14403.1 - 0.00012 21.6 0.1 1.8 7.9 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_17 PF13207.6 OAJ14403.1 - 0.00019 21.9 0.0 0.23 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ14403.1 - 0.00028 20.2 0.1 0.69 9.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Viral_helicase1 PF01443.18 OAJ14403.1 - 0.00038 20.3 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 OAJ14403.1 - 0.0005 20.3 0.0 0.06 13.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.22 OAJ14403.1 - 0.00071 18.8 0.0 0.86 8.7 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_11 PF13086.6 OAJ14403.1 - 0.0011 18.8 1.3 1.2 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OAJ14403.1 - 0.0017 17.9 0.0 0.54 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 OAJ14403.1 - 0.0025 18.0 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 OAJ14403.1 - 0.0027 16.9 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 OAJ14403.1 - 0.0031 16.7 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 OAJ14403.1 - 0.0048 16.6 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 OAJ14403.1 - 0.005 15.8 0.0 0.76 8.6 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase Lzipper-MIP1 PF14389.6 OAJ14403.1 - 0.0074 16.6 0.1 0.04 14.2 0.0 2.2 2 0 0 2 2 1 1 Leucine-zipper of ternary complex factor MIP1 PhoH PF02562.16 OAJ14403.1 - 0.0082 15.6 0.6 2 7.8 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein ATPase_2 PF01637.18 OAJ14403.1 - 0.0088 16.0 0.0 1.9 8.4 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea SKI PF01202.22 OAJ14403.1 - 0.018 15.1 0.1 6.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase TniB PF05621.11 OAJ14403.1 - 0.021 14.2 0.0 20 4.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 OAJ14403.1 - 0.047 13.7 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SPX PF03105.19 OAJ14403.1 - 0.05 13.5 0.9 0.081 12.8 0.9 1.3 1 0 0 1 1 1 0 SPX domain PduV-EutP PF10662.9 OAJ14403.1 - 0.064 13.0 0.0 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 OAJ14403.1 - 0.068 13.1 0.1 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 OAJ14403.1 - 0.099 13.0 1.2 13 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 OAJ14403.1 - 0.13 12.2 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 OAJ14403.1 - 0.23 11.3 0.0 6.6 6.5 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein DUF4810 PF16068.5 OAJ14403.1 - 0.33 11.5 0.6 0.79 10.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) APC_u14 PF16635.5 OAJ14403.1 - 2.4 8.7 4.7 0.45 11.1 0.2 2.0 2 0 0 2 2 1 0 Unstructured region on APC between SAMP and APC_crr SOG2 PF10428.9 OAJ14403.1 - 5.1 6.2 11.3 8.5 5.4 11.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein FAD-oxidase_C PF02913.19 OAJ14404.1 - 7.7e-62 209.2 0.4 1e-61 208.7 0.0 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAJ14404.1 - 1.3e-33 115.7 1.1 2.6e-33 114.7 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.14 OAJ14404.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Ilar_coat PF01787.16 OAJ14404.1 - 0.22 11.3 0.6 0.83 9.4 0.0 2.1 2 1 0 2 2 2 0 Ilarvirus coat protein CHCH PF06747.13 OAJ14405.1 - 0.00012 22.1 5.1 0.00012 22.1 5.1 2.5 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 OAJ14405.1 - 0.00019 21.4 10.7 0.0036 17.3 3.6 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OAJ14405.1 - 0.12 12.7 9.0 4 7.8 0.6 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 OAJ14405.1 - 8.2 6.9 11.0 2.1 8.8 4.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Proteasome PF00227.26 OAJ14406.1 - 4.4e-06 26.3 0.0 0.00019 21.0 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit GFO_IDH_MocA_C PF02894.17 OAJ14406.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Sporozoite_P67 PF05642.11 OAJ14406.1 - 0.16 10.0 0.7 0.16 10.0 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4589 PF15252.6 OAJ14406.1 - 0.23 11.4 2.8 0.3 11.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Nop14 PF04147.12 OAJ14406.1 - 4.7 5.3 5.2 5.4 5.1 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane PF01061.24 OAJ14422.1 - 1.4e-30 106.3 15.7 2.5e-30 105.5 15.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ14422.1 - 1.2e-25 90.6 0.1 2.1e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ14422.1 - 1.2e-06 28.6 0.2 0.01 15.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ14422.1 - 3.8e-05 23.3 0.6 0.00027 20.6 0.4 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ14422.1 - 0.00033 21.1 0.1 0.00071 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ14422.1 - 0.0014 18.5 0.2 0.004 17.1 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAJ14422.1 - 0.0034 17.6 0.4 0.015 15.5 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAJ14422.1 - 0.0093 16.5 0.1 0.015 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ14422.1 - 0.025 14.3 0.1 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAJ14422.1 - 0.08 12.5 0.4 0.64 9.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAJ14422.1 - 0.1 12.5 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OAJ14422.1 - 0.11 12.2 0.1 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 OAJ14422.1 - 0.16 11.0 0.1 0.39 9.7 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FAD_binding_8 PF08022.12 OAJ14423.1 - 1.2e-18 67.1 0.0 2.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ14423.1 - 7.4e-14 52.2 0.1 4.2e-12 46.4 0.0 3.2 2 2 1 3 3 3 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ14423.1 - 1.2e-10 41.5 9.4 2.8e-10 40.4 9.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAJ14424.1 - 1.2e-18 67.1 0.0 2.6e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ14424.1 - 4.1e-15 56.2 0.0 7.3e-14 52.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ14424.1 - 1e-10 41.8 6.1 2.7e-10 40.5 6.1 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component PAT1 PF09770.9 OAJ14425.1 - 1.3e-111 374.4 12.3 5.5e-73 246.6 0.0 4.3 2 2 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Transposase_20 PF02371.16 OAJ14425.1 - 0.15 12.4 2.2 0.18 12.1 0.1 2.2 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family ELYS PF13934.6 OAJ14426.1 - 1.6e-08 34.8 1.8 4.1e-08 33.5 1.8 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly Polysacc_deac_1 PF01522.21 OAJ14444.1 - 2.4e-17 63.0 0.0 4.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_transf_17 PF04724.13 OAJ14445.1 - 8.7e-125 416.4 0.0 1.1e-124 416.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glycos_transf_1 PF00534.20 OAJ14446.1 - 4.5e-29 101.2 0.1 1.2e-27 96.6 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ14446.1 - 3.5e-24 85.7 0.0 7.7e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ14446.1 - 9.9e-23 81.0 0.0 1.8e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAJ14446.1 - 1.2e-12 48.6 0.0 3.6e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAJ14446.1 - 0.0023 18.3 0.6 2.3 8.7 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferases group 1 Cation_ATPase_C PF00689.21 OAJ14447.1 - 1.6e-44 151.8 5.3 1.6e-44 151.8 5.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAJ14447.1 - 2.5e-37 128.2 0.0 2.5e-37 128.2 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAJ14447.1 - 2.3e-21 75.7 0.4 6.4e-21 74.2 0.4 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ14447.1 - 2.2e-15 57.5 8.5 8.3e-15 55.6 8.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ14447.1 - 9.7e-10 38.0 0.1 5.6e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ14447.1 - 0.00019 21.2 1.7 0.023 14.5 0.4 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OAJ14466.1 - 3.7e-47 160.9 0.0 6.6e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14466.1 - 8.7e-33 113.7 0.0 1.5e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ14466.1 - 4.5e-05 22.9 0.0 4.5e-05 22.9 0.0 2.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ14466.1 - 0.0055 16.1 0.0 0.017 14.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like UPF0242 PF06785.11 OAJ14466.1 - 2.7 8.1 16.8 0.66 10.0 4.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 OAJ14466.1 - 9 6.7 30.1 21 5.5 13.7 2.9 1 1 1 2 2 2 0 Fez1 LPD34 PF18852.1 OAJ14468.1 - 0.0024 17.5 0.4 0.0042 16.7 0.4 1.3 1 0 0 1 1 1 1 Large polyvalent protein associated domain 34 Fib_alpha PF08702.10 OAJ14468.1 - 0.26 11.5 1.0 2.4 8.3 0.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 OAJ14468.1 - 3.7 7.8 12.4 0.64 10.2 1.0 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FGAR-AT_N PF18076.1 OAJ14471.1 - 2e-08 34.2 0.0 5.9e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal DUF3719 PF12516.8 OAJ14471.1 - 0.048 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) RCDG1 PF15725.5 OAJ14472.1 - 6.5 7.3 12.3 0.62 10.5 6.3 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF1295 PF06966.12 OAJ14490.1 - 4.9e-42 144.1 0.0 8.9e-42 143.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAJ14490.1 - 0.045 14.2 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 OAJ14490.1 - 0.1 12.6 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Pilin_N PF07790.11 OAJ14490.1 - 0.16 12.9 0.0 0.41 11.6 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Chorismate_synt PF01264.21 OAJ14491.1 - 7.1e-12 44.7 0.1 9.2e-12 44.3 0.1 1.1 1 0 0 1 1 1 1 Chorismate synthase MMR_HSR1_Xtn PF16897.5 OAJ14493.1 - 7.3e-39 132.1 0.1 1.5e-38 131.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAJ14493.1 - 4.5e-22 77.8 0.0 8.7e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAJ14493.1 - 1.1e-20 73.9 0.0 2.2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ14493.1 - 1.2e-09 37.9 0.1 3.3e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ14493.1 - 0.0011 19.0 0.1 0.32 11.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 OAJ14493.1 - 0.019 14.0 0.5 0.052 12.5 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OAJ14493.1 - 0.07 12.7 0.6 10 5.6 0.6 3.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 OAJ14493.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 OAJ14493.1 - 0.23 11.3 1.5 4.8 7.1 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase PLDc_2 PF13091.6 OAJ14494.1 - 5.3e-17 62.0 0.0 4.5e-11 42.8 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain Vault PF01505.18 OAJ14495.1 - 0.22 11.7 1.0 0.56 10.4 0.4 2.0 2 0 0 2 2 2 0 Major Vault Protein repeat domain PIF1 PF05970.14 OAJ14497.1 - 6.7e-14 51.8 0.0 9.8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ14498.1 - 2.2e-28 99.8 0.3 3.3e-28 99.2 0.3 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Abhydrolase_1 PF00561.20 OAJ14518.1 - 6.5e-26 91.5 0.2 7.7e-22 78.2 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ14518.1 - 1.5e-11 44.3 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAJ14518.1 - 0.022 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SMC_Nse1 PF07574.13 OAJ14519.1 - 4.2e-26 92.1 0.1 8.3e-24 84.5 0.1 2.3 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 OAJ14519.1 - 3.9e-05 23.9 8.0 6.4e-05 23.2 8.0 1.4 1 0 0 1 1 1 1 RING-like domain Myc_N PF01056.18 OAJ14519.1 - 0.0015 18.5 2.1 0.0022 18.0 2.1 1.2 1 0 0 1 1 1 1 Myc amino-terminal region CDC45 PF02724.14 OAJ14519.1 - 0.03 12.6 2.5 0.039 12.3 2.5 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ14519.1 - 0.18 11.1 11.7 0.37 10.1 11.7 1.5 1 1 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 OAJ14519.1 - 0.59 9.9 7.2 1.1 9.0 7.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SURF2 PF05477.11 OAJ14519.1 - 0.66 9.6 4.7 0.96 9.1 4.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PBP1_TM PF14812.6 OAJ14519.1 - 1.4 9.3 19.9 0.15 12.4 12.2 2.6 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FANCL_C PF11793.8 OAJ14519.1 - 1.8 8.8 5.5 8 6.7 4.9 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain Nop14 PF04147.12 OAJ14519.1 - 5.2 5.1 11.9 7.6 4.6 11.9 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ14519.1 - 6.7 4.7 6.1 8.6 4.3 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 OAJ14520.1 - 2.5e-24 85.1 10.6 0.00036 21.3 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ14520.1 - 0.0036 17.6 0.0 9.9 6.5 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BAF1_ABF1 PF04684.13 OAJ14520.1 - 5.1 6.0 7.8 0.36 9.8 1.4 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor STE PF02200.16 OAJ14521.1 - 4.4e-35 120.4 0.0 7.3e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor DDE_Tnp_4 PF13359.6 OAJ14522.1 - 9.1e-33 113.2 0.0 1.4e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ14522.1 - 4.3e-08 33.1 0.0 7.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ14522.1 - 7.7e-08 32.2 0.0 4e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 OAJ14522.1 - 0.0031 17.2 0.0 0.0082 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_20 PF12840.7 OAJ14522.1 - 0.0041 17.2 0.1 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 OAJ14522.1 - 0.041 14.0 0.6 0.57 10.3 0.0 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_11 PF08279.12 OAJ14522.1 - 0.048 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 HTH domain V-ATPase_H_N PF03224.14 OAJ14522.1 - 0.058 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H Sigma70_r4 PF04545.16 OAJ14522.1 - 0.061 12.8 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_36 PF13730.6 OAJ14522.1 - 0.064 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 OAJ14522.1 - 0.11 12.3 1.4 0.42 10.5 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain CDC45 PF02724.14 OAJ14523.1 - 3.9 5.6 12.1 6.1 5.0 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-SNAP50_C PF12251.8 OAJ14524.1 - 6.6e-08 32.5 0.0 1.5e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF4246 PF14033.6 OAJ14548.1 - 1.9e-121 406.3 0.0 2.3e-121 406.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.9 OAJ14548.1 - 0.1 12.4 0.0 0.77 9.5 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe dioxygenase PGAP1 PF07819.13 OAJ14549.1 - 1.8e-61 207.8 0.0 2.9e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 OAJ14549.1 - 0.031 13.9 0.0 0.084 12.5 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ14549.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAJ14549.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Utp12 PF04003.12 OAJ14550.1 - 0.0012 19.1 0.8 0.0018 18.6 0.8 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Helicase_C PF00271.31 OAJ14552.1 - 3.8e-11 43.3 0.0 2.3e-08 34.3 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ14552.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ14552.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RR_TM4-6 PF06459.12 OAJ14552.1 - 0.77 9.5 2.8 1.2 8.9 2.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rrn6 PF10214.9 OAJ14552.1 - 1.8 7.0 4.8 2.6 6.5 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Rab5ip PF07019.12 OAJ14553.1 - 5.6e-15 55.7 5.0 7.2e-15 55.4 5.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) tRNA-synt_1e PF01406.19 OAJ14554.1 - 1.1e-121 405.8 0.0 3.3e-73 246.7 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAJ14554.1 - 3.8e-07 29.2 0.8 0.00024 20.0 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 OAJ14554.1 - 4.7e-05 23.8 0.2 0.00029 21.3 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.22 OAJ14554.1 - 0.00015 20.2 0.3 0.0028 16.0 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 OAJ14554.1 - 0.0025 16.8 0.3 0.64 8.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 OAJ14554.1 - 0.025 13.5 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) RTC4 PF14474.6 OAJ14576.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.6 1 1 0 1 1 1 0 RTC4-like domain Nop14 PF04147.12 OAJ14577.1 - 8.7e-05 21.0 11.2 8.7e-05 21.0 11.2 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAJ14577.1 - 0.013 14.9 14.9 0.015 14.8 14.9 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 OAJ14577.1 - 0.12 12.8 1.5 0.15 12.5 1.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 OAJ14577.1 - 0.15 10.1 23.7 0.2 9.7 23.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 OAJ14577.1 - 0.17 12.0 4.0 0.23 11.6 4.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 OAJ14577.1 - 0.18 11.1 20.5 0.27 10.6 20.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OAJ14577.1 - 0.19 10.0 14.3 0.23 9.7 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 OAJ14577.1 - 0.23 11.6 0.7 0.29 11.3 0.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF4637 PF15470.6 OAJ14577.1 - 0.46 10.2 16.8 0.66 9.7 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Roughex PF06020.11 OAJ14577.1 - 0.66 9.0 17.1 0.93 8.5 17.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein RR_TM4-6 PF06459.12 OAJ14577.1 - 2 8.2 9.2 2.6 7.8 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.18 OAJ14577.1 - 2.3 7.0 9.2 2.6 6.8 9.2 1.2 1 0 0 1 1 1 0 Hsp90 protein PI3K_1B_p101 PF10486.9 OAJ14577.1 - 2.7 5.7 6.5 3.7 5.2 6.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpp10 PF04006.12 OAJ14577.1 - 2.7 6.3 21.1 3.4 6.0 21.1 1.0 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 OAJ14577.1 - 6.3 6.0 20.2 8.2 5.7 20.2 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 OAJ14577.1 - 7.1 5.3 7.0 8.7 5.0 7.0 1.1 1 0 0 1 1 1 0 Presenilin TFB6 PF17110.5 OAJ14577.1 - 7.2 6.3 11.1 13 5.5 11.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 OAJ14577.1 - 7.4 5.7 12.1 9 5.4 12.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.13 OAJ14577.1 - 8.2 5.3 20.5 11 4.9 20.5 1.1 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.9 OAJ14577.1 - 8.4 5.4 29.7 11 5.1 29.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 OAJ14577.1 - 8.6 4.3 9.2 12 3.8 9.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SART-1 PF03343.13 OAJ14595.1 - 2.7e-139 465.6 60.9 3.3e-139 465.3 60.9 1.0 1 0 0 1 1 1 1 SART-1 family DNA_Packaging_2 PF11123.8 OAJ14595.1 - 0.034 14.3 0.2 0.1 12.8 0.2 1.8 1 0 0 1 1 1 0 DNA packaging protein MFS_1 PF07690.16 OAJ14596.1 - 2.4e-41 141.8 29.7 2.4e-41 141.8 29.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ14596.1 - 5.1e-11 42.1 3.1 5.1e-11 42.1 3.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ14596.1 - 1.1e-05 24.1 5.8 1.5e-05 23.6 5.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Actin PF00022.19 OAJ14597.1 - 1.6e-58 198.3 0.0 4.7e-34 117.7 0.0 2.3 2 1 0 2 2 2 2 Actin DUF4677 PF15726.5 OAJ14597.1 - 0.055 13.6 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) FAD-oxidase_C PF02913.19 OAJ14597.1 - 0.069 12.8 0.8 0.11 12.1 0.3 1.5 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Cornichon PF03311.14 OAJ14598.1 - 8.9e-53 177.8 12.8 1e-52 177.6 12.8 1.0 1 0 0 1 1 1 1 Cornichon protein GTP_EFTU PF00009.27 OAJ14599.1 - 5.2e-19 68.5 0.0 1.5e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAJ14599.1 - 1.2e-09 38.5 1.1 3.5e-09 36.9 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ14599.1 - 0.0023 18.0 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Erythro-docking PF09277.11 OAJ14599.1 - 0.037 13.9 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 Erythronolide synthase, docking PduV-EutP PF10662.9 OAJ14599.1 - 0.066 13.0 0.1 19 5.0 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CBS PF00571.28 OAJ14600.1 - 1.3e-14 54.3 8.3 0.00073 19.9 0.4 5.7 6 0 0 6 6 6 4 CBS domain YL1 PF05764.13 OAJ14601.1 - 1.5 8.9 7.2 0.12 12.5 1.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Rer1 PF03248.13 OAJ14602.1 - 2.5e-75 251.9 0.0 3.8e-75 251.4 0.0 1.2 1 1 0 1 1 1 1 Rer1 family RVT_1 PF00078.27 OAJ14617.1 - 1.1e-24 87.2 0.0 1.8e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ14617.1 - 8.3e-22 77.1 0.0 3.8e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ14617.1 - 2.7e-16 59.7 0.0 4.3e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ14617.1 - 8.4e-16 57.8 0.3 2e-15 56.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ14617.1 - 8e-09 35.7 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF936 PF06075.12 OAJ14619.1 - 0.035 13.0 12.9 0.042 12.8 12.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SOG2 PF10428.9 OAJ14619.1 - 0.95 8.6 20.0 1.2 8.2 20.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1387 PF07139.11 OAJ14619.1 - 1.2 8.8 11.0 1.5 8.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hydrophobin PF01185.18 OAJ14620.1 - 3.1 8.5 11.2 4.2 8.1 0.1 3.3 2 1 1 3 3 3 0 Fungal hydrophobin Chitin_synth_2 PF03142.15 OAJ14621.1 - 9.2e-246 816.5 0.0 1.2e-245 816.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAJ14621.1 - 1.5e-89 301.0 0.0 8.7e-89 298.5 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 OAJ14621.1 - 2.2e-15 56.5 0.1 1.5e-11 44.3 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAJ14621.1 - 8.7e-15 55.2 0.0 6.2e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ14621.1 - 7.4e-14 52.1 3.1 7.4e-14 52.1 3.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.11 OAJ14621.1 - 4.8e-13 48.8 0.0 1e-11 44.6 0.0 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.26 OAJ14621.1 - 4.3e-09 36.4 0.0 4.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAJ14621.1 - 1.5e-05 24.6 0.0 4.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 UQ_con PF00179.26 OAJ14643.1 - 3.7e-45 153.0 0.0 4.6e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ14643.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B DIM PF08194.12 OAJ14644.1 - 0.36 11.1 1.7 0.54 10.5 1.7 1.3 1 0 0 1 1 1 0 DIM protein HTH_10 PF04967.12 OAJ14645.1 - 0.0069 16.2 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 HTH DNA binding domain DSPc PF00782.20 OAJ14646.1 - 3.9e-18 65.6 0.0 1.8e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ14646.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CPSase_L_D2 PF02786.17 OAJ14646.1 - 1.5 8.3 2.6 6.1 6.3 0.9 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF3128 PF11326.8 OAJ14648.1 - 1.4e-19 70.2 1.3 2.6e-19 69.4 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) ER_lumen_recept PF00810.18 OAJ14648.1 - 0.16 12.8 0.0 0.23 12.3 0.0 1.3 1 0 0 1 1 1 0 ER lumen protein retaining receptor Mus7 PF09462.10 OAJ14649.1 - 1.6e-101 341.1 0.0 2e-101 340.7 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family ETF_QO PF05187.13 OAJ14666.1 - 1.2e-16 60.7 3.3 5.8e-07 29.6 0.0 2.4 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DUF3016 PF11454.8 OAJ14666.1 - 0.047 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Hexokinase_2 PF03727.16 OAJ14668.1 - 6.7e-80 268.0 0.0 9.7e-80 267.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAJ14668.1 - 1.4e-66 224.2 0.0 2.2e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DEAD PF00270.29 OAJ14669.1 - 2e-38 131.9 0.1 3.8e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ14669.1 - 6.7e-27 94.0 0.1 2.7e-25 88.9 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ14669.1 - 3.8e-07 30.3 0.0 8.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ14669.1 - 0.03 13.7 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-RING_UBOX PF13445.6 OAJ14670.1 - 1.9e-07 31.0 2.8 1.9e-07 31.0 2.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ14670.1 - 2.9e-06 27.0 4.4 2.9e-06 27.0 4.4 3.6 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ14670.1 - 1e-05 25.3 2.2 1e-05 25.3 2.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ14670.1 - 0.00016 21.7 4.8 0.00016 21.7 4.8 3.5 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ14670.1 - 0.00073 19.5 8.1 0.00073 19.5 8.1 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ14670.1 - 0.0047 16.8 7.6 0.0047 16.8 7.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ14670.1 - 0.37 11.1 20.9 0.076 13.4 12.0 3.2 2 1 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 OAJ14670.1 - 0.69 9.8 19.7 0.027 14.3 4.3 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 PRIMA1 PF16101.5 OAJ14672.1 - 0.18 11.8 9.4 0.49 10.4 4.0 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DndB PF14072.6 OAJ14688.1 - 1.8e-104 349.7 0.0 2e-104 349.5 0.0 1.0 1 0 0 1 1 1 1 DNA-sulfur modification-associated Clp_N PF02861.20 OAJ14688.1 - 0.025 14.7 0.1 0.091 12.9 0.0 2.1 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component AAA_23 PF13476.6 OAJ14690.1 - 6.5e-11 43.1 3.2 6.5e-11 43.1 3.2 3.3 2 1 0 2 2 1 1 AAA domain SMC_N PF02463.19 OAJ14690.1 - 4.3e-09 36.1 4.4 0.00044 19.8 0.8 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain PAPS_reduct PF01507.19 OAJ14690.1 - 1.4e-08 35.0 0.0 1.4e-08 35.0 0.0 3.0 3 1 0 3 3 3 1 Phosphoadenosine phosphosulfate reductase family AAA_21 PF13304.6 OAJ14690.1 - 0.00053 19.9 0.7 0.024 14.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 OAJ14690.1 - 0.0033 16.2 23.5 0.073 11.7 0.6 3.1 3 0 0 3 3 3 2 AAA domain Spc7 PF08317.11 OAJ14690.1 - 0.0036 16.2 25.9 0.13 11.1 3.9 2.9 2 0 0 2 2 2 2 Spc7 kinetochore protein AAA_29 PF13555.6 OAJ14690.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain XhlA PF10779.9 OAJ14690.1 - 0.02 15.1 0.4 0.02 15.1 0.4 3.4 3 0 0 3 3 3 0 Haemolysin XhlA AAA_15 PF13175.6 OAJ14690.1 - 0.091 12.5 0.1 6.1 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain EzrA PF06160.12 OAJ14690.1 - 0.12 10.5 15.8 0.24 9.6 1.4 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ABC_tran PF00005.27 OAJ14690.1 - 0.17 12.4 7.8 11 6.5 0.0 4.1 2 1 0 2 2 2 0 ABC transporter Snapin_Pallidin PF14712.6 OAJ14690.1 - 0.19 12.2 31.4 3.7 8.0 2.4 4.8 3 1 1 4 4 4 0 Snapin/Pallidin cwf21 PF08312.12 OAJ14690.1 - 0.29 11.3 10.3 0.3 11.3 1.9 4.4 3 1 0 3 3 3 0 cwf21 domain AAA_19 PF13245.6 OAJ14690.1 - 0.49 10.7 3.8 19 5.6 0.4 3.1 3 0 0 3 3 2 0 AAA domain Allexi_40kDa PF05549.11 OAJ14690.1 - 0.62 9.5 8.5 5.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein MscS_porin PF12795.7 OAJ14690.1 - 0.77 9.3 55.0 0.21 11.1 13.3 3.7 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF2730 PF10805.8 OAJ14690.1 - 1.3 9.1 7.3 0.91 9.7 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.10 OAJ14690.1 - 2.2 8.5 14.5 13 5.9 0.5 3.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MEDS PF14417.6 OAJ14690.1 - 5.2 6.9 7.7 3.3 7.5 2.0 3.0 2 1 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Baculo_PEP_C PF04513.12 OAJ14690.1 - 5.6 7.0 10.3 2 8.5 1.1 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 OAJ14690.1 - 8.3 7.0 8.6 20 5.7 2.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OAJ14690.1 - 8.7 6.4 18.3 3.6 7.7 0.7 3.8 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) KxDL PF10241.9 OAJ14690.1 - 9 6.7 17.3 0.74 10.1 0.1 4.2 3 1 0 3 3 3 0 Uncharacterized conserved protein Fmp27_WPPW PF10359.9 OAJ14690.1 - 9.7 4.9 19.3 7.1 5.4 3.4 2.2 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF421 PF04239.12 OAJ14691.1 - 2.3e-12 46.6 0.0 3.1e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF421) Fer2_BFD PF04324.15 OAJ14691.1 - 0.02 15.2 0.5 0.036 14.4 0.5 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Y1_Tnp PF01797.16 OAJ14693.1 - 6.7e-05 23.0 0.1 8.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Transposase IS200 like ABC1 PF03109.16 OAJ14693.1 - 0.17 12.0 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Aminotran_4 PF01063.19 OAJ14694.1 - 2.1e-31 109.5 0.0 2.4e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Isochorismatase PF00857.20 OAJ14695.1 - 2.3e-22 80.0 0.0 2.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family MerR_1 PF13411.6 OAJ14697.1 - 1.8e-12 47.2 0.0 3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 OAJ14697.1 - 8.6e-09 35.0 1.2 8.6e-09 35.0 1.2 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 OAJ14697.1 - 1.8e-06 28.4 0.7 2.3e-06 28.0 0.7 1.2 1 0 0 1 1 1 1 MerR, DNA binding Bro-N PF02498.17 OAJ14698.1 - 5.9e-07 30.1 0.0 8.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 BRO family, N-terminal domain PAAR_motif PF05488.13 OAJ14699.1 - 2.9e-17 62.6 10.8 2.6e-15 56.3 0.5 2.9 1 1 2 3 3 3 3 PAAR motif DUF5347 PF17282.2 OAJ14700.1 - 0.0048 17.2 0.1 0.0061 16.8 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5347) Ank_2 PF12796.7 OAJ14719.1 - 3.8e-11 43.4 0.2 3.2e-06 27.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ14719.1 - 6.1e-07 29.9 0.1 0.011 16.3 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ14719.1 - 0.00061 20.0 0.0 3.7 8.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ14719.1 - 0.0076 16.7 0.0 1.9 9.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OAJ14719.1 - 0.0099 16.3 0.1 74 4.4 0.0 4.9 5 1 0 5 5 5 0 Ankyrin repeat NDC10_II PF16787.5 OAJ14720.1 - 2.9e-46 158.0 0.0 4.7e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ14720.1 - 0.0013 19.1 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_28 PF13518.6 OAJ14720.1 - 0.065 13.4 0.9 0.75 10.0 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 OAJ14720.1 - 0.2 11.5 3.0 0.41 10.5 0.0 3.1 3 1 1 4 4 4 0 Homeodomain-like domain HA2 PF04408.23 OAJ14721.1 - 7.6e-15 55.1 0.1 7.6e-15 55.1 0.1 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ14721.1 - 1.7e-09 37.9 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ14721.1 - 1.8e-07 31.5 0.0 1.3e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain T2SSE PF00437.20 OAJ14721.1 - 0.0026 16.9 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 OAJ14721.1 - 0.0038 17.5 0.1 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OAJ14721.1 - 0.013 15.2 0.2 1 9.1 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 OAJ14721.1 - 0.098 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.15 OAJ14721.1 - 0.13 12.2 0.0 8.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OAJ14721.1 - 0.18 11.2 0.1 0.88 9.0 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein FAM176 PF14851.6 OAJ14721.1 - 3.5 7.3 10.9 26 4.4 0.0 4.0 4 0 0 4 4 4 0 FAM176 family zf-C2H2 PF00096.26 OAJ14722.1 - 2.6e-25 87.4 58.8 0.00068 20.0 1.9 10.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ14722.1 - 2.5e-15 55.8 58.2 0.0077 17.0 1.4 10.5 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ14722.1 - 2.7e-05 24.3 12.7 1.9 8.9 0.0 7.1 7 0 0 7 7 7 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAJ14722.1 - 2.7e-05 24.4 4.7 0.0029 17.9 1.9 11.3 12 0 0 12 12 12 3 Zinc-finger double domain RNA_pol_3_Rpc31 PF11705.8 OAJ14722.1 - 0.00046 20.5 2.8 0.00046 20.5 2.8 4.7 4 1 0 4 4 3 1 DNA-directed RNA polymerase III subunit Rpc31 FOXP-CC PF16159.5 OAJ14722.1 - 0.0045 17.6 28.4 0.78 10.4 0.7 6.9 6 1 1 7 7 7 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 OAJ14722.1 - 0.26 11.6 21.7 1.8 8.9 1.7 6.1 3 2 3 6 6 6 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 OAJ14722.1 - 0.76 9.9 11.2 9.3 6.4 0.0 5.0 6 0 0 6 6 6 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 OAJ14722.1 - 0.9 9.7 4.6 29 4.8 0.1 4.6 4 1 1 5 5 5 0 Aberrant zinc-finger AGH PF17558.2 OAJ14722.1 - 3 8.0 5.7 2.7 8.2 0.3 3.4 3 0 0 3 3 3 0 Androgenic gland hormone Ogr_Delta PF04606.12 OAJ14722.1 - 3.8 7.6 8.1 1.6 8.8 0.5 4.1 5 0 0 5 5 5 0 Ogr/Delta-like zinc finger DUF1741 PF08427.10 OAJ14724.1 - 6.9e-05 22.6 3.7 0.022 14.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1741) Ribosomal_L7Ae PF01248.26 OAJ14740.1 - 7.4e-22 76.9 0.1 1.8e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAJ14740.1 - 0.0028 17.7 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 LicD PF04991.13 OAJ14740.1 - 0.23 11.6 5.3 0.3 11.2 5.3 1.2 1 0 0 1 1 1 0 LicD family CDC27 PF09507.10 OAJ14740.1 - 1.8 7.9 29.7 2.3 7.5 29.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4050 PF13259.6 OAJ14740.1 - 2 8.7 11.6 4 7.7 11.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) BAF1_ABF1 PF04684.13 OAJ14740.1 - 5.3 6.0 19.4 6.4 5.7 19.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med3 PF11593.8 OAJ14740.1 - 8.5 5.4 9.2 2.2 7.4 6.3 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Fe-S_biosyn PF01521.20 OAJ14741.1 - 3.1e-15 56.3 0.0 4.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MutS_V PF00488.21 OAJ14743.1 - 3.9e-65 219.4 0.8 7.8e-65 218.4 0.2 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAJ14743.1 - 7.1e-34 117.7 0.2 3e-33 115.7 0.2 2.1 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ14743.1 - 8.2e-34 116.2 0.3 2.3e-33 114.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain I Acetyltransf_13 PF13880.6 OAJ14743.1 - 1e-13 51.0 0.0 2.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OAJ14743.1 - 3.6e-13 49.1 2.3 7.6e-13 48.1 2.3 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MutS_II PF05188.17 OAJ14743.1 - 6.7e-12 45.9 0.2 2.1e-11 44.3 0.2 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAJ14743.1 - 2.1e-06 28.0 0.5 1e-05 25.8 0.2 2.2 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 OAJ14743.1 - 0.043 13.5 2.0 0.12 12.1 0.2 2.7 3 0 0 3 3 3 0 AAA domain SKN1 PF03935.15 OAJ14744.1 - 3.5e-175 583.2 0.7 4.1e-175 583.0 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RhoGEF PF00621.20 OAJ14745.1 - 1.3e-25 90.7 0.5 1.3e-25 90.7 0.5 1.7 2 0 0 2 2 2 1 RhoGEF domain PPR_2 PF13041.6 OAJ14766.1 - 5.5e-33 112.9 0.0 3.4e-10 39.9 0.0 8.6 8 1 2 10 10 10 6 PPR repeat family PPR_3 PF13812.6 OAJ14766.1 - 1.6e-27 95.4 0.0 9.6e-13 48.0 0.0 5.9 4 2 1 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 OAJ14766.1 - 1.1e-25 88.0 5.0 0.00018 21.5 0.0 11.0 11 2 0 11 11 11 5 PPR repeat PPR_1 PF12854.7 OAJ14766.1 - 5.7e-18 64.3 0.6 7.2e-07 28.8 0.0 6.5 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 OAJ14766.1 - 1.3e-13 50.8 0.0 1.4e-11 44.2 0.0 3.4 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 OAJ14766.1 - 0.012 15.6 0.0 33 4.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.23 OAJ14767.1 - 6.4e-39 132.6 1.0 6.2e-38 129.4 0.6 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ14767.1 - 1.7e-27 95.8 0.0 3.4e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain CBF PF03914.17 OAJ14768.1 - 2.1e-39 135.3 0.1 2.1e-39 135.3 0.1 2.7 2 1 0 2 2 2 1 CBF/Mak21 family DUF2722 PF10846.8 OAJ14768.1 - 0.0041 16.1 7.2 0.0041 16.1 7.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) Cnd1 PF12717.7 OAJ14768.1 - 0.024 14.7 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ14768.1 - 0.048 12.2 0.0 0.44 9.1 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Suf PF05843.14 OAJ14768.1 - 4.3 7.2 11.8 0.31 11.0 3.1 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) CxC1 PF18802.1 OAJ14770.1 - 4.9e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ14770.1 - 9.1e-05 22.6 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 OAJ14770.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases TetR_C_15 PF17918.1 OAJ14770.1 - 0.15 12.9 3.5 0.71 10.7 0.2 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Transposase_21 PF02992.14 OAJ14790.1 - 1.2e-12 47.5 0.1 3.3e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 NDC10_II PF16787.5 OAJ14792.1 - 1.2e-50 172.4 0.0 1.8e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ14792.1 - 2.2e-13 50.3 0.0 5.3e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DNA_repr_REX1B PF14966.6 OAJ14792.1 - 0.019 15.6 0.1 0.097 13.3 0.1 2.3 1 0 0 1 1 1 0 DNA repair REX1-B Sporozoite_P67 PF05642.11 OAJ14792.1 - 0.044 11.9 3.7 0.078 11.0 3.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP_synt_H PF05493.13 OAJ14793.1 - 9.4e-21 74.0 3.1 1.1e-20 73.8 3.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 OAJ14793.1 - 0.59 9.8 2.3 0.64 9.7 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Abhydrolase_3 PF07859.13 OAJ14794.1 - 2.9e-30 105.7 0.1 6.8e-21 75.1 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ14812.1 - 3.5e-39 134.8 0.0 3.3e-31 108.8 0.0 2.8 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ14812.1 - 9.9e-11 41.1 0.0 3.2e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 OAJ14812.1 - 0.0045 15.9 0.1 0.14 11.0 0.0 3.0 4 0 0 4 4 4 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAJ14812.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family NDC10_II PF16787.5 OAJ14813.1 - 2.6e-32 112.2 0.0 3.8e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ14813.1 - 5.9e-10 39.3 0.3 5.9e-10 39.3 0.3 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Phage_integrase PF00589.22 OAJ14813.1 - 3.9e-06 26.8 0.0 1.5e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Phage integrase family Got1 PF04178.12 OAJ14815.1 - 1.2e-28 99.7 19.2 1.6e-28 99.3 19.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4187 PF13821.6 OAJ14816.1 - 5.8e-17 61.2 4.4 1.3e-16 60.1 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DPBB_1 PF03330.18 OAJ14817.1 - 5.9e-07 29.7 0.1 1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Ribonuc_red_sm PF00268.21 OAJ14818.1 - 3.8e-122 407.1 1.2 4.7e-122 406.8 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Glyco_transf_90 PF05686.12 OAJ14831.1 - 1.5e-25 90.0 6.5 1.4e-22 80.2 6.6 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3533 PF12051.8 OAJ14832.1 - 4.3e-73 246.4 11.0 5.5e-73 246.1 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ibs_toxin PF13956.6 OAJ14832.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.4 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system EphA2_TM PF14575.6 OAJ14832.1 - 5.8 7.9 5.5 22 6.0 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain CDH-cyt PF16010.5 OAJ14833.1 - 1.2e-12 47.9 4.3 2.6e-12 46.8 4.3 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAJ14833.1 - 6.3e-09 36.1 8.7 6.3e-09 36.1 8.7 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAJ14833.1 - 0.0042 17.3 0.1 0.0093 16.2 0.1 1.7 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 OAJ14833.1 - 0.0084 16.3 8.5 0.029 14.5 8.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) Ecl1 PF12855.7 OAJ14833.1 - 1.1 10.4 13.4 1.8 9.7 13.4 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2427 PF10348.9 OAJ14833.1 - 1.5 8.6 8.8 0.62 9.9 5.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF3533 PF12051.8 OAJ14834.1 - 3.8e-79 266.4 17.8 4.4e-79 266.1 17.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) BatD PF13584.6 OAJ14834.1 - 0.18 10.6 1.5 8.4 5.1 0.0 2.2 2 0 0 2 2 2 0 Oxygen tolerance HAD_2 PF13419.6 OAJ14835.1 - 2.5e-17 63.5 0.0 1.1e-11 45.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ14835.1 - 1.2e-14 55.1 0.6 4.3e-14 53.3 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ14835.1 - 3.8e-05 23.7 0.0 8.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAJ14835.1 - 0.028 14.8 0.0 0.57 10.6 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase GDPD PF03009.17 OAJ14836.1 - 8.5e-34 117.4 2.1 3.9e-33 115.3 2.1 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 OAJ14836.1 - 2.7e-05 24.5 2.9 6.8e-05 23.2 2.9 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Stevor PF17410.2 OAJ14837.1 - 0.009 15.6 0.2 0.014 15.0 0.2 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF1180 PF06679.12 OAJ14837.1 - 0.011 16.2 6.0 0.033 14.6 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) RCR PF12273.8 OAJ14837.1 - 0.058 14.1 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2905 PF11146.8 OAJ14837.1 - 0.17 12.0 0.7 0.32 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Esterase PF00756.20 OAJ14856.1 - 0.00031 20.5 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Asp2 PF16929.5 OAJ14856.1 - 0.032 13.2 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Ribosomal_S9 PF00380.19 OAJ14856.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 FHA PF00498.26 OAJ14857.1 - 7.4e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ14857.1 - 0.001 19.4 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BUD22 PF09073.10 OAJ14857.1 - 3.4 6.9 18.7 2.3 7.5 6.2 2.2 2 0 0 2 2 2 0 BUD22 Pox_MCEL PF03291.16 OAJ14858.1 - 1.2e-73 248.1 0.0 1.7e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OAJ14858.1 - 5.4e-12 46.3 0.0 1.3e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ14858.1 - 2.6e-10 40.3 0.0 3.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ14858.1 - 2.1e-08 34.2 0.0 3.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ14858.1 - 9.9e-08 32.5 0.0 2.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ14858.1 - 1.3e-06 29.1 0.0 3.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAJ14858.1 - 0.00037 19.8 0.0 0.002 17.3 0.0 1.9 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.14 OAJ14858.1 - 0.004 16.7 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAJ14858.1 - 0.026 13.9 0.1 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PTS_EIIC_2 PF13303.6 OAJ14858.1 - 0.62 9.0 3.6 1 8.3 3.6 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC WD40 PF00400.32 OAJ14859.1 - 1.5e-25 89.0 12.8 7.1e-05 23.5 0.6 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2415 PF10313.9 OAJ14859.1 - 0.0025 17.7 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Gaa1 PF04114.14 OAJ14860.1 - 2.9e-71 241.0 4.0 2.5e-52 178.6 0.0 3.3 3 0 0 3 3 3 3 Gaa1-like, GPI transamidase component LRR_6 PF13516.6 OAJ14861.1 - 4.5e-12 45.0 12.4 0.13 12.4 0.1 8.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 OAJ14861.1 - 8.4e-09 35.6 11.4 0.49 10.9 0.6 6.9 1 1 9 10 10 10 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ14861.1 - 2.4e-07 30.4 0.0 3.3 8.6 0.0 7.2 9 0 0 9 9 7 1 Leucine Rich Repeat LRR_8 PF13855.6 OAJ14861.1 - 1.6e-06 27.8 10.9 1 9.2 0.1 7.2 6 3 1 7 7 7 3 Leucine rich repeat Abhydrolase_6 PF12697.7 OAJ14861.1 - 0.015 15.9 0.1 0.023 15.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Paf1 PF03985.13 OAJ14861.1 - 0.12 11.4 9.0 0.15 11.0 9.0 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 OAJ14861.1 - 0.22 9.7 14.4 0.27 9.4 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 OAJ14861.1 - 0.3 10.2 21.1 0.44 9.6 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATP11 PF06644.11 OAJ14861.1 - 0.48 10.2 2.2 0.65 9.7 2.2 1.2 1 0 0 1 1 1 0 ATP11 protein SDA1 PF05285.12 OAJ14861.1 - 1.5 8.2 16.1 2 7.8 16.1 1.1 1 0 0 1 1 1 0 SDA1 TMEM247 PF15444.6 OAJ14861.1 - 2.1 8.3 6.6 3.5 7.6 6.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 DNA_pol_phi PF04931.13 OAJ14861.1 - 2.5 6.1 22.7 3.6 5.6 22.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OAJ14861.1 - 3 7.5 8.2 5.2 6.7 8.2 1.4 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 OAJ14861.1 - 3.3 7.9 20.9 5 7.3 20.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 OAJ14861.1 - 3.4 7.7 10.2 5.9 6.9 10.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 OAJ14861.1 - 4.9 7.0 15.3 8.4 6.2 15.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pes-10 PF07149.11 OAJ14861.1 - 6 5.8 12.9 8.4 5.3 12.9 1.2 1 0 0 1 1 1 0 Pes-10 Pox_Ag35 PF03286.14 OAJ14861.1 - 6.4 6.5 10.9 10 5.8 10.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 OAJ14861.1 - 9.4 6.7 21.8 23 5.5 21.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.11 OAJ14861.1 - 9.4 4.6 11.8 13 4.2 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CS PF04969.16 OAJ14862.1 - 0.00038 21.4 0.2 0.00076 20.5 0.0 1.6 2 0 0 2 2 2 1 CS domain Oxidored_q6 PF01058.22 OAJ14881.1 - 9.3e-23 80.5 0.1 1.4e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit OPT PF03169.15 OAJ14882.1 - 1.8e-182 608.2 53.5 2.1e-182 608.0 53.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 OAJ14883.1 - 1.6e-65 221.2 0.0 2.6e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14883.1 - 1.8e-33 116.0 0.0 2.6e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14883.1 - 2.1e-08 33.8 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ14883.1 - 0.00081 19.4 0.2 0.00081 19.4 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ14883.1 - 0.00089 18.3 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ14883.1 - 0.0014 17.5 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ14883.1 - 0.0016 17.9 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ14883.1 - 0.07 12.7 0.2 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NDC10_II PF16787.5 OAJ14884.1 - 6.8e-62 209.3 0.0 1.3e-61 208.4 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ14884.1 - 5.1e-21 74.8 0.9 1.1e-20 73.8 0.9 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes OPT PF03169.15 OAJ14885.1 - 6.2e-190 632.9 53.3 7.1e-190 632.7 53.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dimer_Tnp_hAT PF05699.14 OAJ14886.1 - 1.5e-23 82.4 0.0 3.2e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAJ14886.1 - 0.00063 19.6 0.0 0.0027 17.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) zinc_ribbon_4 PF13717.6 OAJ14886.1 - 0.21 11.5 0.9 0.43 10.5 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain PP_kinase_C PF13090.6 OAJ14886.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Glyco_hydro_32N PF00251.20 OAJ14906.1 - 1.9e-36 126.2 0.1 5.7e-25 88.5 0.4 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ14906.1 - 1.9e-21 76.7 0.0 3.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Pkinase PF00069.25 OAJ14907.1 - 5e-73 245.7 0.1 5e-73 245.7 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14907.1 - 2.8e-52 177.6 1.1 6.5e-52 176.4 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 OAJ14907.1 - 1.4e-22 79.7 0.0 3.5e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 OAJ14907.1 - 1.8e-11 44.5 0.9 3.9e-11 43.4 0.9 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 OAJ14907.1 - 1.3e-06 27.4 1.0 4.2e-06 25.8 1.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ14907.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ14907.1 - 0.0011 17.9 1.3 0.0018 17.3 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain PH_11 PF15413.6 OAJ14907.1 - 0.0028 18.1 1.1 0.18 12.2 1.1 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 OAJ14907.1 - 0.027 14.4 6.8 0.037 13.9 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family MAT1 PF06391.13 OAJ14907.1 - 0.88 9.4 6.1 1.5 8.6 6.1 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF3915 PF13054.6 OAJ14907.1 - 1.4 8.9 8.9 2.8 7.9 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Rotamase PF00639.21 OAJ14907.1 - 2.8 8.9 8.1 7.6 7.6 8.1 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain RR_TM4-6 PF06459.12 OAJ14907.1 - 3.3 7.5 8.2 5.9 6.6 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gpr1_Fun34_YaaH PF01184.19 OAJ14909.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family RQC PF09382.10 OAJ14933.1 - 2e-23 82.4 0.1 5e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 OAJ14933.1 - 1.8e-19 70.2 0.0 3.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ14933.1 - 1.9e-19 70.0 0.0 4.5e-18 65.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAJ14933.1 - 1.4e-17 64.2 2.8 1.4e-17 64.2 2.8 2.1 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 OAJ14933.1 - 3.2e-11 43.1 0.0 8.2e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Di19_C PF14571.6 OAJ14933.1 - 0.029 14.9 0.3 1.3 9.6 1.4 3.2 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Ribosomal_S9 PF00380.19 OAJ14934.1 - 7.2e-44 149.2 0.2 1.3e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Fungal_trans PF04082.18 OAJ14935.1 - 1.4e-17 63.6 0.0 5.5e-17 61.7 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 OAJ14936.1 - 2.5e-37 128.9 0.0 4.1e-35 121.7 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAJ14936.1 - 4.2e-05 23.3 0.1 6.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Sterol-sensing PF12349.8 OAJ14937.1 - 1.5e-40 138.5 12.6 3.2e-40 137.4 12.6 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAJ14937.1 - 4.8e-12 44.8 4.0 7.2e-12 44.2 4.0 1.1 1 0 0 1 1 1 1 Patched family His_Phos_2 PF00328.22 OAJ14938.1 - 1.7e-72 244.9 0.2 2.4e-72 244.4 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAJ14938.1 - 7.4e-35 119.0 0.1 1.5e-34 118.0 0.1 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAJ14938.1 - 4.5e-06 26.4 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DIOX_N PF14226.6 OAJ14959.1 - 2.3e-16 60.6 0.0 4.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAJ14959.1 - 5.1e-16 59.0 0.0 9.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.23 OAJ14960.1 - 3.9e-64 216.6 0.1 7e-64 215.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ14960.1 - 6.5e-19 68.3 0.0 4.1e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ14960.1 - 9.9e-11 41.9 0.1 4.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 OAJ14960.1 - 0.054 13.8 16.6 0.39 11.1 16.6 2.5 1 1 0 1 1 1 0 HSA HDA2-3 PF11496.8 OAJ14960.1 - 0.09 11.9 0.2 9.4 5.3 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Tex_N PF09371.10 OAJ14960.1 - 0.094 12.4 3.8 0.67 9.6 3.7 2.2 2 0 0 2 2 2 0 Tex-like protein N-terminal domain NmrA PF05368.13 OAJ14962.1 - 5.4e-14 52.3 0.0 6.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ14962.1 - 4.4e-07 30.0 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAJ14962.1 - 0.082 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0121 PF03661.13 OAJ14963.1 - 1.2e-37 129.6 7.9 1.6e-37 129.2 7.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2101 PF09874.9 OAJ14963.1 - 0.073 12.8 0.1 0.073 12.8 0.1 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) DeoC PF01791.9 OAJ14964.1 - 1.5e-11 44.4 1.0 3.1e-11 43.3 1.0 1.5 1 1 0 1 1 1 1 DeoC/LacD family aldolase RebB PF11747.8 OAJ14964.1 - 0.069 13.3 8.1 0.22 11.7 8.1 1.8 1 0 0 1 1 1 0 Killing trait PMT PF02366.18 OAJ14965.1 - 1.4e-44 152.5 4.3 1.9e-44 152.1 4.3 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4402 PF14352.6 OAJ14965.1 - 0.34 11.5 2.2 1.1 10.0 2.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) LHC PF00556.20 OAJ14966.1 - 0.051 13.8 2.2 0.064 13.5 0.2 2.0 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit PT PF04886.12 OAJ14967.1 - 0.019 14.5 6.5 16 5.2 0.0 4.1 3 1 0 4 4 4 0 PT repeat Methyltransf_32 PF13679.6 OAJ14967.1 - 0.05 13.6 0.7 0.064 13.2 0.7 1.3 1 0 0 1 1 1 0 Methyltransferase domain ESP PF16590.5 OAJ14967.1 - 0.42 10.9 4.6 3.7 7.9 2.0 2.9 1 1 2 3 3 3 0 Exocrine gland-secreting peptide DDE_Tnp_4 PF13359.6 OAJ14984.1 - 2.9e-21 75.8 0.0 4.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ14984.1 - 2.9e-07 30.3 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ14984.1 - 5.5e-05 22.9 0.0 9.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAJ14984.1 - 0.011 16.1 0.7 0.023 15.1 0.1 1.7 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 OAJ14985.1 - 6.1e-18 65.6 2.9 1.1e-17 64.8 2.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ14985.1 - 7.3e-07 29.5 3.2 1.1e-06 28.9 3.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ14985.1 - 0.011 16.0 1.8 0.021 15.0 1.8 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ14985.1 - 0.011 15.9 1.9 0.025 14.8 1.9 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OAJ14985.1 - 0.071 13.2 2.8 0.13 12.3 2.8 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CENP-B_dimeris PF09026.10 OAJ14985.1 - 0.08 13.3 5.7 0.17 12.3 5.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YebG PF07130.12 OAJ14985.1 - 0.14 12.0 0.2 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 YebG protein NOA36 PF06524.12 OAJ14985.1 - 1.1 8.5 4.6 1.5 8.1 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein VWA_2 PF13519.6 OAJ14986.1 - 2.3e-26 92.5 0.1 7e-26 91.0 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAJ14986.1 - 2.3e-10 41.0 1.0 3.5e-10 40.4 0.3 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAJ14986.1 - 8.9e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OAJ14986.1 - 0.00021 21.0 2.7 0.018 15.0 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif CAF1 PF04857.20 OAJ14987.1 - 9.6e-22 77.5 0.0 5.9e-11 42.1 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease Peptidase_M24 PF00557.24 OAJ14988.1 - 3.2e-47 160.9 0.0 3.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DDE_Tnp_4 PF13359.6 OAJ14989.1 - 9e-21 74.2 0.0 1.9e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ14989.1 - 6.9e-05 22.6 0.8 0.031 13.9 0.0 3.3 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 OAJ14990.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain G-alpha PF00503.20 OAJ14991.1 - 3.7e-123 411.2 1.6 4.3e-123 411.0 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ14991.1 - 9.1e-17 61.1 0.6 9.6e-12 44.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ14991.1 - 2.2e-05 23.9 0.3 0.0047 16.3 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ14991.1 - 0.00069 19.8 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 OAJ14991.1 - 0.0034 17.2 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 CHC2 zinc finger MCM PF00493.23 OAJ14991.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MMR_HSR1 PF01926.23 OAJ14991.1 - 0.022 14.9 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ14991.1 - 0.06 13.1 3.4 0.061 13.1 0.1 2.4 2 1 1 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAJ14991.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arm PF00514.23 OAJ14992.1 - 1.2e-74 244.3 10.4 3e-12 46.1 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ14992.1 - 5.2e-21 74.7 5.8 2e-07 31.3 0.0 5.6 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 OAJ14992.1 - 4.1e-18 64.7 0.0 2e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 OAJ14992.1 - 4.9e-16 58.9 6.2 1.1e-06 28.9 0.2 5.5 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 OAJ14992.1 - 1.5e-15 56.0 5.3 0.00047 20.2 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.20 OAJ14992.1 - 7.7e-15 55.1 1.9 1.5e-14 54.1 1.3 1.8 2 0 0 2 2 2 1 Importin beta binding domain RICTOR_V PF14668.6 OAJ14992.1 - 3.3e-06 27.2 1.2 0.091 13.0 0.1 4.1 2 2 2 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 OAJ14992.1 - 0.0056 15.3 0.0 0.014 14.0 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.16 OAJ14992.1 - 0.018 15.7 4.3 2.6 9.0 0.0 4.9 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat CTNNBL PF08216.11 OAJ14992.1 - 0.17 12.1 0.6 7.5 6.8 0.0 3.6 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear tRNA-synt_1e PF01406.19 OAJ15010.1 - 0.62 9.3 2.9 0.92 8.8 2.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TORC_M PF12885.7 OAJ15010.1 - 5.7 6.8 6.4 3.5 7.5 0.3 2.7 3 0 0 3 3 3 0 Transducer of regulated CREB activity middle domain ABC_tran PF00005.27 OAJ15011.1 - 5.8e-37 127.3 1.4 1.3e-19 71.1 0.0 3.9 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OAJ15011.1 - 6.2e-08 32.4 1.9 0.33 10.4 0.1 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ15011.1 - 6.8e-07 29.4 7.1 0.0092 15.8 0.0 4.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OAJ15011.1 - 8.9e-06 25.7 3.6 8.9e-06 25.7 3.6 2.6 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 OAJ15011.1 - 2.4e-05 24.0 0.3 0.052 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ15011.1 - 2.8e-05 24.1 0.5 0.0083 16.0 0.2 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OAJ15011.1 - 0.0009 19.8 7.7 0.4 11.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 OAJ15011.1 - 0.0017 18.4 0.4 0.26 11.4 0.1 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 OAJ15011.1 - 0.0041 17.3 0.0 0.074 13.3 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit HopA1 PF17914.1 OAJ15011.1 - 0.016 14.9 0.6 0.067 13.0 0.1 2.1 2 0 0 2 2 2 0 HopA1 effector protein family MeaB PF03308.16 OAJ15011.1 - 0.017 14.1 1.1 0.06 12.3 0.4 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 OAJ15011.1 - 0.026 14.5 0.1 1.1 9.1 0.0 3.4 4 0 0 4 4 4 0 NTPase RNA_helicase PF00910.22 OAJ15011.1 - 0.053 13.9 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAJ15011.1 - 0.063 13.2 0.0 16 5.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 OAJ15011.1 - 0.082 12.5 0.7 5.7 6.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OAJ15011.1 - 0.12 12.4 0.7 19 5.2 0.0 3.8 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) DUF1515 PF07439.11 OAJ15011.1 - 0.14 12.2 1.0 18 5.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) AAA_7 PF12775.7 OAJ15011.1 - 0.14 11.6 0.0 0.93 9.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ15011.1 - 0.71 10.2 5.7 0.44 10.9 0.2 3.2 2 2 0 2 2 2 0 AAA ATPase domain MRFAP1 PF15155.6 OAJ15011.1 - 5.9 7.4 11.7 0.5 10.9 0.6 3.1 3 0 0 3 3 2 0 MORF4 family-associated protein1 Aa_trans PF01490.18 OAJ15012.1 - 6.7e-07 28.4 0.5 0.0036 16.1 2.4 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Yip1 PF04893.17 OAJ15012.1 - 0.22 11.2 0.0 0.22 11.2 0.0 4.1 5 0 0 5 5 5 0 Yip1 domain COPI_C PF06957.11 OAJ15012.1 - 3.6 6.2 5.8 6.1 5.5 5.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF2070 PF09843.9 OAJ15015.1 - 6.4 4.9 7.7 1 7.6 3.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) tRNA_bind PF01588.20 OAJ15016.1 - 8.5e-27 93.1 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 OAJ15016.1 - 9.9e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ15016.1 - 0.0076 16.2 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ15016.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 OAJ15017.1 - 1.3e-11 44.4 7.1 2.2e-11 43.7 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAL_FSA PF00923.19 OAJ15039.1 - 1.7e-97 326.2 0.3 1.9e-97 326.1 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 OAJ15041.1 - 8.7e-06 25.3 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 OAJ15041.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ15041.1 - 0.00043 19.4 0.0 0.00062 18.9 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OAJ15041.1 - 0.0078 15.0 2.8 0.069 11.9 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OAJ15041.1 - 0.0089 15.4 2.4 0.015 14.6 2.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 OAJ15042.1 - 5.1e-44 149.9 0.1 1.2e-43 148.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ15042.1 - 4e-09 36.3 0.6 1.8e-08 34.2 0.0 2.3 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ15042.1 - 1.8e-08 34.5 0.0 1.1e-07 31.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ15042.1 - 1.3e-07 32.2 0.2 4.6e-05 23.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ15042.1 - 2.4e-07 31.0 0.1 6.4e-07 29.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 OAJ15042.1 - 3.8e-06 26.6 0.1 9.4e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 OAJ15042.1 - 8.1e-06 25.2 0.0 3.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAJ15042.1 - 8.1e-05 22.9 0.6 0.014 15.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ15042.1 - 0.00035 20.3 0.0 0.00086 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ15042.1 - 0.00086 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ15042.1 - 0.00086 19.9 0.0 0.0044 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ15042.1 - 0.00089 19.5 0.1 0.0026 18.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 OAJ15042.1 - 0.0012 18.8 0.1 0.0028 17.6 0.0 1.7 2 0 0 2 2 1 1 NTPase TIP49 PF06068.13 OAJ15042.1 - 0.0024 17.1 0.0 0.0059 15.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAJ15042.1 - 0.0029 17.6 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ15042.1 - 0.005 17.0 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAJ15042.1 - 0.0056 16.2 0.1 0.031 13.8 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ15042.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 OAJ15042.1 - 0.0082 15.5 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ15042.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ15042.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAJ15042.1 - 0.02 14.8 0.1 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 OAJ15042.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 OAJ15042.1 - 0.021 14.2 0.0 0.83 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 OAJ15042.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAJ15042.1 - 0.038 13.9 0.8 0.54 10.1 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prot_ATP_OB_N PF17758.1 OAJ15042.1 - 0.041 13.5 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Bac_DnaA PF00308.18 OAJ15042.1 - 0.061 13.2 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.6 OAJ15042.1 - 0.061 13.1 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAJ15042.1 - 0.066 12.3 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ15042.1 - 0.078 12.5 0.5 0.28 10.7 0.5 1.8 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 OAJ15042.1 - 0.088 11.7 0.1 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.6 OAJ15042.1 - 0.12 12.9 1.0 0.64 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ15042.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAJ15042.1 - 0.19 11.4 0.3 1.8 8.2 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain ArfGap PF01412.18 OAJ15043.1 - 4.5e-40 136.4 0.2 4.5e-40 136.4 0.2 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NAM-associated PF14303.6 OAJ15043.1 - 0.0024 18.6 3.4 0.04 14.6 3.4 2.6 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF4175 PF13779.6 OAJ15043.1 - 0.03 12.3 16.7 0.047 11.6 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BBS2_C PF14782.6 OAJ15043.1 - 0.053 12.3 3.5 0.074 11.8 3.5 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal CSRNP_N PF16019.5 OAJ15043.1 - 0.41 10.5 8.9 1.1 9.2 8.9 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus NUDIX PF00293.28 OAJ15045.1 - 0.00032 20.7 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SCP2 PF02036.17 OAJ15046.1 - 1.7e-26 92.6 1.4 1.9e-26 92.5 1.4 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ15046.1 - 7.3e-05 23.0 0.5 8.9e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ost5 PF05251.12 OAJ15047.1 - 5.4e-16 58.6 6.8 7.1e-16 58.2 6.8 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Fig1 PF12351.8 OAJ15047.1 - 0.013 15.4 0.4 0.013 15.4 0.4 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Aminotran_1_2 PF00155.21 OAJ15048.1 - 1.8e-80 270.9 0.0 2e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SWIRM PF04433.17 OAJ15063.1 - 1.5e-30 105.4 0.0 3.1e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_2 PF16496.5 OAJ15063.1 - 3.9e-30 105.1 6.9 3.4e-21 75.6 1.8 3.5 4 0 0 4 4 4 3 SWIRM-associated domain at the N-terminal SWIRM-assoc_1 PF16495.5 OAJ15063.1 - 5.1e-29 100.1 5.4 1.7e-28 98.4 5.4 2.0 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAJ15063.1 - 2.7e-08 33.9 0.1 5.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 OAJ15063.1 - 2.5e-07 30.4 1.0 4.3e-07 29.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OAJ15063.1 - 2.6e-07 30.8 0.0 7.5e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ODC_AZ PF02100.17 OAJ15065.1 - 9.8e-11 41.6 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme LAGLIDADG_3 PF14528.6 OAJ15066.1 - 0.00023 21.4 0.0 0.0042 17.4 0.0 2.3 2 0 0 2 2 2 1 LAGLIDADG-like domain Hom_end PF05204.14 OAJ15066.1 - 0.011 15.9 0.0 0.5 10.6 0.0 2.5 2 0 0 2 2 2 0 Homing endonuclease Calc_CGRP_IAPP PF00214.19 OAJ15067.1 - 0.067 13.6 0.1 0.075 13.4 0.1 1.3 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family Pcc1 PF09341.10 OAJ15087.1 - 2e-19 69.5 1.8 2.4e-19 69.2 1.8 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3323 PF11796.8 OAJ15088.1 - 6.3e-05 23.0 0.4 6.3e-05 23.0 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) Eclosion PF04736.12 OAJ15088.1 - 0.021 14.5 0.5 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 Eclosion hormone E3_binding PF02817.17 OAJ15088.1 - 0.11 12.9 0.9 23 5.4 0.1 3.3 3 0 0 3 3 3 0 e3 binding domain Glyco_hydro_9 PF00759.19 OAJ15088.1 - 0.13 11.6 11.0 0.63 9.4 3.5 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Transp_inhibit PF18791.1 OAJ15089.1 - 0.062 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain TFIIA PF03153.13 OAJ15090.1 - 0.00011 22.3 1.7 0.00012 22.3 0.3 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3318 PF11780.8 OAJ15090.1 - 0.16 11.9 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF3598 PF12204.8 OAJ15091.1 - 0.27 10.7 0.0 19 4.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) GATA PF00320.27 OAJ15092.1 - 0.00019 20.9 2.1 0.00031 20.3 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Rod_cone_degen PF15201.6 OAJ15092.1 - 0.082 13.0 0.1 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 Progressive rod-cone degeneration T2SSM PF04612.12 OAJ15092.1 - 2.8 8.0 6.0 0.54 10.3 2.6 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M NAM-associated PF14303.6 OAJ15092.1 - 5.6 7.6 8.3 0.78 10.4 0.6 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DHHC PF01529.20 OAJ15093.1 - 3.1e-33 114.7 3.3 3.1e-33 114.7 3.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pox_A12 PF04651.13 OAJ15093.1 - 0.23 11.5 9.4 0.42 10.6 9.4 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Arc_PepC_II PF06847.11 OAJ15093.1 - 0.61 10.6 2.0 1.7 9.2 2.0 1.8 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II TAF4 PF05236.14 OAJ15093.1 - 1.7 8.3 14.6 3.3 7.4 14.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Miga PF10265.9 OAJ15093.1 - 1.7 7.5 5.1 2.7 6.8 5.1 1.2 1 0 0 1 1 1 0 Mitoguardin Sigma70_ner PF04546.13 OAJ15093.1 - 2 8.3 12.9 5 7.0 8.6 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region PI3K_1B_p101 PF10486.9 OAJ15093.1 - 2.5 5.7 14.4 4 5.1 14.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MOSC_N PF03476.16 OAJ15094.1 - 2.1e-17 63.1 0.0 4.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAJ15094.1 - 1.3e-16 60.9 0.0 2.3e-15 56.8 0.0 2.2 1 1 0 1 1 1 1 MOSC domain zf-RING_2 PF13639.6 OAJ15095.1 - 3.7e-09 36.8 0.6 3.7e-09 36.8 0.6 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OAJ15095.1 - 4.1e-09 36.6 2.2 1.1e-08 35.2 2.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 OAJ15095.1 - 3.3e-06 27.2 0.9 3.3e-06 27.2 0.9 2.8 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 OAJ15095.1 - 3.1e-05 23.7 0.7 3.1e-05 23.7 0.7 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ15095.1 - 6.2e-05 22.8 0.2 6.2e-05 22.8 0.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ15095.1 - 8.3e-05 22.4 0.7 8.3e-05 22.4 0.7 2.1 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ15095.1 - 0.00013 21.9 5.7 0.00014 21.8 0.3 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ15095.1 - 0.0007 19.6 2.3 0.0022 18.0 2.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ15095.1 - 0.00087 19.1 2.2 0.00087 19.1 2.2 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ15095.1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 2.8 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OAJ15095.1 - 0.004 16.7 0.5 0.011 15.3 0.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAJ15095.1 - 0.0073 16.3 4.2 0.0084 16.1 1.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OAJ15095.1 - 0.086 13.0 4.2 1.4 9.2 4.2 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 OAJ15095.1 - 0.16 11.8 1.1 0.4 10.6 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HypA PF01155.19 OAJ15095.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OAJ15095.1 - 0.42 10.8 9.1 0.16 12.1 0.6 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 OAJ15095.1 - 0.51 10.4 2.6 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 OAJ15095.1 - 0.82 9.2 5.6 14 5.3 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OAJ15095.1 - 1.6 8.8 7.1 4.1 7.5 0.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-C3H2C3 PF17122.5 OAJ15095.1 - 1.8 8.7 5.0 0.51 10.4 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger Mit_KHE1 PF10173.9 OAJ15113.1 - 8.4e-55 185.8 0.3 1.2e-54 185.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Histone_H2A_C PF16211.5 OAJ15114.1 - 1.6e-14 53.4 0.3 2.4e-14 52.7 0.3 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ15114.1 - 2.8e-09 37.4 0.0 4.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ATP_bind_1 PF03029.17 OAJ15115.1 - 1.1e-67 228.4 0.0 3.5e-63 213.6 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein SRP54 PF00448.22 OAJ15115.1 - 0.002 17.8 0.4 0.013 15.1 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OAJ15115.1 - 0.0024 17.9 0.0 0.043 13.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ15115.1 - 0.0069 16.7 0.2 0.02 15.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 OAJ15115.1 - 0.0078 15.8 0.0 0.65 9.5 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OAJ15115.1 - 0.014 15.1 0.1 0.06 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OAJ15115.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 OAJ15115.1 - 0.02 14.8 0.0 3.8 7.4 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 OAJ15115.1 - 0.024 14.8 0.1 0.024 14.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ15115.1 - 0.038 14.4 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 OAJ15115.1 - 0.043 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 OAJ15115.1 - 0.043 12.8 0.1 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 OAJ15115.1 - 0.076 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAJ15115.1 - 0.15 11.8 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 OAJ15115.1 - 0.16 11.6 0.1 19 4.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OAJ15115.1 - 0.23 12.0 0.1 0.23 12.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 OAJ15115.1 - 0.25 11.0 0.1 0.58 9.9 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 OAJ15115.1 - 4.1 7.4 6.3 0.56 10.3 0.4 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain Thiolase_N PF00108.23 OAJ15116.1 - 8.2e-70 235.1 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ15116.1 - 4e-41 139.5 0.6 1.2e-40 137.9 0.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ15116.1 - 0.0017 18.0 0.7 0.025 14.1 0.7 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ15116.1 - 0.0045 16.8 1.3 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 OAJ15116.1 - 0.006 16.7 0.1 0.019 15.1 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NADH_B2 PF14813.6 OAJ15118.1 - 0.0013 18.5 0.6 0.0016 18.2 0.6 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Ribosomal_S16 PF00886.19 OAJ15119.1 - 3.5e-25 87.9 0.1 9.6e-25 86.4 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S16 VWA PF00092.28 OAJ15120.1 - 1.1e-09 38.8 0.0 2.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAJ15120.1 - 3.3e-08 34.1 0.0 7.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 OAJ15120.1 - 0.0044 16.9 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.18 OAJ15120.1 - 0.038 13.7 0.0 2.6 7.7 0.0 2.2 1 1 1 2 2 2 0 Integrin beta chain VWA domain MC1 PF05854.11 OAJ15120.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 TssR PF17643.1 OAJ15120.1 - 0.12 10.3 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR Ribosomal_L14 PF00238.19 OAJ15121.1 - 4.8e-34 117.1 0.1 1.1e-33 115.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Kri1_C PF12936.7 OAJ15121.1 - 2e-22 79.1 0.1 2e-22 79.1 0.1 3.8 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 OAJ15121.1 - 1.7e-21 76.7 10.6 1.7e-21 76.7 10.6 5.7 4 2 1 5 5 5 1 KRI1-like family RRM_1 PF00076.22 OAJ15122.1 - 8.5e-32 108.8 0.0 3.8e-12 45.9 0.0 4.0 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ15122.1 - 0.00011 22.1 0.0 1.1 9.3 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ15122.1 - 0.0005 20.1 0.0 1.3 9.1 0.0 4.7 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM PF05172.13 OAJ15122.1 - 0.00096 19.1 0.0 0.013 15.4 0.0 2.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAJ15122.1 - 0.039 13.5 0.0 0.54 9.9 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 OAJ15122.1 - 0.15 12.9 1.6 1.6 9.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat P22_portal PF16510.5 OAJ15144.1 - 1.5 7.3 29.1 0.59 8.7 10.0 2.1 2 0 0 2 2 2 0 Phage P22-like portal protein FAD_binding_3 PF01494.19 OAJ15145.1 - 2.5e-25 89.5 0.0 3.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ15145.1 - 1.1e-05 24.8 0.2 0.03 13.5 0.0 2.9 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ15145.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAJ15145.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 OAJ15145.1 - 0.03 13.4 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.27 OAJ15145.1 - 0.031 14.8 0.1 0.28 11.8 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ15145.1 - 0.071 12.3 0.2 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ15145.1 - 0.28 10.7 1.1 1.8 8.0 0.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf_Hakai PF18408.1 OAJ15146.1 - 0.081 12.6 2.2 4.7 7.0 0.1 2.4 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 OAJ15146.1 - 8.2 6.6 7.5 0.53 10.4 0.1 2.6 3 1 0 3 3 3 0 Zic proteins zinc finger domain RabGAP-TBC PF00566.18 OAJ15147.1 - 2.6e-15 56.6 0.0 9.8e-06 25.4 0.0 3.7 3 1 0 3 3 3 3 Rab-GTPase-TBC domain AAA_lid_8 PF17868.1 OAJ15147.1 - 0.24 11.3 0.0 0.53 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain Transposase_21 PF02992.14 OAJ15148.1 - 1.5e-08 34.2 0.0 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ15148.1 - 4e-06 26.4 0.1 7.3e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Prok-RING_4 PF14447.6 OAJ15148.1 - 2.9 7.8 7.2 0.43 10.5 2.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SOG2 PF10428.9 OAJ15149.1 - 0.77 8.9 4.6 5.8 6.0 1.5 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein PspB PF06667.12 OAJ15151.1 - 0.0058 16.7 1.1 0.0058 16.7 1.1 2.9 2 1 1 3 3 3 1 Phage shock protein B DivIC PF04977.15 OAJ15151.1 - 0.025 14.4 3.0 0.025 14.4 3.0 2.9 3 0 0 3 3 3 0 Septum formation initiator Peptidase_S46 PF10459.9 OAJ15151.1 - 0.1 11.2 16.3 0.14 10.8 16.3 1.0 1 0 0 1 1 1 0 Peptidase S46 CALCOCO1 PF07888.11 OAJ15151.1 - 0.2 10.5 32.5 0.12 11.2 3.7 2.1 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 OAJ15151.1 - 1.4 9.5 13.6 1 10.0 0.4 3.6 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Paralemmin PF03285.15 OAJ15151.1 - 1.6 8.2 16.8 0.11 12.1 9.3 2.3 1 1 2 3 3 3 0 Paralemmin FlaC_arch PF05377.11 OAJ15151.1 - 2 8.9 8.8 10 6.6 0.5 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 OAJ15151.1 - 3.9 7.5 12.5 19 5.3 5.3 2.4 1 1 1 2 2 2 0 FlxA-like protein TSC22 PF01166.18 OAJ15151.1 - 4.4 7.7 9.8 1.6 9.1 0.5 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family HAD_2 PF13419.6 OAJ15171.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ15171.1 - 0.095 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like COX6B PF02297.17 OAJ15171.1 - 0.12 12.6 0.3 0.25 11.6 0.0 1.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF1295 PF06966.12 OAJ15172.1 - 5.6e-35 121.0 0.1 3.9e-34 118.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) PIP49_N PF14875.6 OAJ15173.1 - 0.02 14.8 6.1 0.021 14.7 6.1 1.0 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 RNA_pol_Rpb2_5 PF04567.17 OAJ15173.1 - 0.079 13.5 1.3 6.5 7.4 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 Collagen PF01391.18 OAJ15174.1 - 2.1e-28 97.8 130.4 3.2e-11 42.8 36.2 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Pro_isomerase PF00160.21 OAJ15176.1 - 2.2e-42 145.0 0.0 4.3e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 OAJ15176.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF2406 PF10295.9 OAJ15176.1 - 0.4 11.4 2.0 12 6.7 0.2 2.9 1 1 1 2 2 2 0 Uncharacterised protein (DUF2406) Rtf2 PF04641.12 OAJ15176.1 - 0.53 9.6 6.5 0.16 11.3 0.1 3.0 3 1 0 3 3 3 0 Rtf2 RING-finger DUF2373 PF10180.9 OAJ15177.1 - 2.3e-14 53.0 0.1 7e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.18 OAJ15177.1 - 0.15 12.1 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Peptidase_S8 PF00082.22 OAJ15178.1 - 1.5e-21 76.9 0.0 4.3e-10 39.3 0.2 2.3 1 1 1 2 2 2 2 Subtilase family PA PF02225.22 OAJ15178.1 - 0.00036 20.5 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.16 OAJ15178.1 - 0.072 13.8 0.0 2.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I9 Thioredoxin PF00085.20 OAJ15196.1 - 7.7e-19 67.6 0.0 8.4e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ15196.1 - 0.0025 18.2 0.0 0.0044 17.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ15196.1 - 0.0027 18.0 0.0 0.0088 16.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OAJ15196.1 - 0.01 15.2 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAJ15196.1 - 0.028 14.4 0.0 0.037 13.9 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family zf-C3HC4_3 PF13920.6 OAJ15197.1 - 0.11 12.4 8.2 0.21 11.5 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rib_recp_KP_reg PF05104.12 OAJ15198.1 - 9.1 7.3 11.9 1.1 10.3 6.1 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Lipocalin_5 PF13924.6 OAJ15199.1 - 0.004 16.9 0.1 0.0063 16.3 0.1 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Orbi_NS3 PF01616.16 OAJ15199.1 - 0.19 11.4 0.1 2 8.1 0.0 2.0 1 1 0 2 2 2 0 Orbivirus NS3 Pep1_7 PF17232.2 OAJ15200.1 - 0.022 15.2 0.3 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 GTP_cyclohydro2 PF00925.20 OAJ15201.1 - 2e-58 196.6 0.0 5e-58 195.3 0.0 1.7 1 1 0 1 1 1 1 GTP cyclohydrolase II EF-hand_7 PF13499.6 OAJ15202.1 - 1.8e-12 47.6 0.1 1.7e-07 31.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAJ15202.1 - 2.9e-12 45.4 0.1 3e-05 23.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OAJ15202.1 - 5.5e-11 41.2 0.0 1.3e-05 24.3 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OAJ15202.1 - 5e-10 39.6 0.0 5.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OAJ15202.1 - 5.4e-05 23.0 0.3 0.007 16.2 0.0 3.4 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ15202.1 - 0.0041 16.5 0.7 0.026 14.0 0.0 2.5 2 1 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 OAJ15202.1 - 0.083 13.8 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain ExbD PF02472.16 OAJ15202.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR PhetRS_B1 PF18262.1 OAJ15202.1 - 0.14 12.4 0.0 8.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain TFIID-18kDa PF02269.16 OAJ15203.1 - 2.5e-17 62.7 0.1 3.3e-07 30.2 0.4 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit FAM75 PF14650.6 OAJ15203.1 - 0.09 12.3 5.8 0.13 11.8 5.8 1.1 1 0 0 1 1 1 0 FAM75 family Serglycin PF04360.12 OAJ15203.1 - 6.1 6.8 12.7 1.5 8.7 9.0 1.8 2 0 0 2 2 2 0 Serglycin Abhydrolase_1 PF00561.20 OAJ15205.1 - 9.1e-14 51.7 0.0 1.9e-09 37.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ15205.1 - 1.3e-13 50.8 0.0 3e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ15205.1 - 5.5e-13 50.0 0.9 7.3e-13 49.6 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAJ15205.1 - 1.6e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAJ15205.1 - 5.6e-09 35.1 0.0 6.4e-06 25.1 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 OAJ15205.1 - 1.8e-06 27.7 0.2 1.2e-05 25.0 0.2 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAJ15205.1 - 2.2e-06 27.3 0.0 2.7e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAJ15205.1 - 7.8e-06 26.0 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OAJ15205.1 - 0.00098 18.8 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.12 OAJ15205.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PAF-AH_p_II PF03403.13 OAJ15205.1 - 0.0046 15.5 0.0 1.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 OAJ15205.1 - 0.032 14.1 0.3 0.087 12.7 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.11 OAJ15205.1 - 0.077 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) LIP PF03583.14 OAJ15205.1 - 0.16 11.2 0.2 0.35 10.1 0.1 1.5 1 1 1 2 2 2 0 Secretory lipase tRNA-synt_1 PF00133.22 OAJ15227.1 - 3.2e-42 144.6 0.0 2.7e-33 115.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAJ15227.1 - 3.8e-13 48.9 0.0 1.4e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAJ15227.1 - 1.1e-10 41.7 0.0 2.5e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAJ15227.1 - 2.7e-07 30.2 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 OAJ15227.1 - 0.0079 15.7 0.2 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 HVSL PF09749.9 OAJ15228.1 - 2.2e-33 115.7 0.0 2.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein NYN PF01936.18 OAJ15229.1 - 9.7e-23 81.3 0.0 2.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 NYN domain CENP-B_dimeris PF09026.10 OAJ15229.1 - 0.8 10.1 4.4 2.1 8.8 4.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAJ15229.1 - 2 6.4 6.7 3 5.8 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi adh_short_C2 PF13561.6 OAJ15230.1 - 1.1e-37 129.9 0.1 1.4e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ15230.1 - 8.7e-30 103.6 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ15230.1 - 1.2e-06 28.6 0.2 1.7e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAJ15230.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 OAJ15230.1 - 0.04 13.2 0.1 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 OAJ15230.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PIG-P PF08510.12 OAJ15231.1 - 1.7e-25 89.2 3.6 2.9e-25 88.5 3.6 1.4 1 1 0 1 1 1 1 PIG-P RabGAP-TBC PF00566.18 OAJ15232.1 - 1.2e-30 106.8 5.7 1.8e-29 103.0 0.0 3.4 4 0 0 4 4 4 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAJ15232.1 - 0.0034 16.9 0.0 0.062 12.8 0.0 2.8 3 1 0 3 3 3 1 Rab-binding domain (RBD) DUF1348 PF07080.11 OAJ15233.1 - 4.5e-60 201.3 5.6 5.1e-60 201.1 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OAJ15233.1 - 3.1e-07 31.0 0.0 4.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAJ15233.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF936 PF06075.12 OAJ15234.1 - 0.02 13.9 0.6 0.021 13.7 0.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) JmjC PF02373.22 OAJ15254.1 - 0.0041 17.5 0.0 0.0042 17.5 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase HALZ PF02183.18 OAJ15255.1 - 0.089 13.0 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper NDC10_II PF16787.5 OAJ15256.1 - 1.1e-63 215.2 0.0 1.6e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ15256.1 - 3.1e-16 59.5 0.3 7.8e-16 58.2 0.3 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes AMP-binding PF00501.28 OAJ15273.1 - 2.8e-91 306.2 0.0 1.2e-60 205.3 0.1 2.4 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ15273.1 - 3.1e-20 72.9 0.1 8.7e-20 71.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTH2 PF01981.16 OAJ15275.1 - 5.3e-47 158.9 1.2 6.8e-47 158.6 1.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_11 PF13414.6 OAJ15275.1 - 0.022 14.4 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 TPR repeat Nuc_deoxyrib_tr PF05014.15 OAJ15275.1 - 0.047 13.7 0.2 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase NDUFA12 PF05071.16 OAJ15276.1 - 1.7e-30 105.7 0.2 2.3e-30 105.3 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 RVT_1 PF00078.27 OAJ15277.1 - 4.2e-08 33.0 0.0 9.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 OAJ15279.1 - 1.2e-45 155.8 0.1 3.1e-45 154.5 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Asp_protease PF09668.10 OAJ15280.1 - 1.7e-58 195.8 0.0 2.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ15280.1 - 4.3e-21 75.3 0.0 1.2e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ15280.1 - 5.4e-10 39.8 0.0 1.8e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 OAJ15280.1 - 2.3e-09 36.8 0.0 4.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ15280.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ15280.1 - 0.0062 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain RVP PF00077.20 OAJ15280.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 OAJ15280.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Profilin PF00235.19 OAJ15281.1 - 5.2e-46 156.0 0.0 5.8e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Profilin DASH_Dad2 PF08654.10 OAJ15282.1 - 1.5e-21 76.6 0.0 2.8e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 DUF5320 PF17253.2 OAJ15282.1 - 0.37 11.9 4.1 1.6 9.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Yippee-Mis18 PF03226.14 OAJ15302.1 - 3.3e-15 56.2 0.0 1.2e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TFIIA PF03153.13 OAJ15302.1 - 0.39 10.6 6.6 0.65 9.9 6.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CiPC PF15800.5 OAJ15302.1 - 5.9 6.5 19.5 10 5.7 19.5 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian Tom22 PF04281.13 OAJ15303.1 - 1.4e-38 131.8 0.6 1.4e-34 118.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 Shadoo PF14999.6 OAJ15303.1 - 0.0037 17.4 3.5 0.0062 16.6 3.5 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Retinal PF15449.6 OAJ15303.1 - 0.072 10.9 1.0 0.092 10.5 1.0 1.1 1 0 0 1 1 1 0 Retinal protein RXT2_N PF08595.11 OAJ15303.1 - 0.3 11.1 1.7 0.45 10.5 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 OAJ15303.1 - 0.74 8.3 5.6 0.84 8.1 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ15303.1 - 1.2 7.1 8.6 1.4 6.9 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAJ15303.1 - 1.6 8.4 10.9 2.4 7.8 10.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.8 OAJ15303.1 - 3.9 6.7 7.6 5.4 6.2 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RNA_pol_3_Rpc31 PF11705.8 OAJ15303.1 - 7 6.8 12.9 9.7 6.4 12.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 OAJ15303.1 - 7.6 6.2 7.3 0.98 9.1 1.5 2.3 3 0 0 3 3 3 0 FAM176 family CENP-B_dimeris PF09026.10 OAJ15303.1 - 7.9 6.9 15.4 15 6.1 15.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PHD PF00628.29 OAJ15304.1 - 1.3e-05 24.9 19.0 2.2e-05 24.2 19.0 1.4 1 0 0 1 1 1 1 PHD-finger UNC-79 PF14776.6 OAJ15304.1 - 5.1 5.7 5.6 8.1 5.1 5.6 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 SET PF00856.28 OAJ15305.1 - 2.3e-14 54.2 0.0 2.3e-14 54.2 0.0 4.0 3 2 0 3 3 3 1 SET domain Ribosomal_L6e PF01159.19 OAJ15307.1 - 2.1e-34 118.4 0.1 2.1e-34 118.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 OAJ15307.1 - 0.0011 19.1 1.7 0.0011 19.1 1.7 2.4 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain RT_RNaseH_2 PF17919.1 OAJ15324.1 - 7.2e-32 109.4 0.0 1.7e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ15324.1 - 3.7e-28 97.9 0.1 8e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ15324.1 - 7.2e-19 68.2 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ15324.1 - 5.5e-16 58.8 0.1 2e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ15324.1 - 1.8e-11 44.0 0.0 5.6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ15324.1 - 0.0056 16.4 0.1 0.047 13.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ15324.1 - 0.041 14.5 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 OAJ15324.1 - 0.33 11.1 6.9 0.025 14.7 2.0 1.8 2 0 0 2 2 2 0 Zinc knuckle Rit1_C PF17184.4 OAJ15325.1 - 1e-86 290.8 0.0 1.8e-86 289.9 0.0 1.4 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 OAJ15325.1 - 2e-10 40.9 0.0 6.9e-09 36.0 0.0 2.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain Fungal_trans PF04082.18 OAJ15326.1 - 2.4e-08 33.3 0.0 4.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ15326.1 - 8.6e-08 32.2 6.1 1.5e-07 31.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma70_r3 PF04539.16 OAJ15327.1 - 0.0077 16.3 0.1 3.2 7.9 0.0 4.1 3 0 0 3 3 3 1 Sigma-70 region 3 ApoLp-III PF07464.11 OAJ15327.1 - 0.04 14.0 0.1 0.04 14.0 0.1 6.6 6 2 0 6 6 6 0 Apolipophorin-III precursor (apoLp-III) DUF1283 PF06932.11 OAJ15327.1 - 0.063 13.5 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) TraC_F_IV PF11130.8 OAJ15327.1 - 0.17 11.4 1.3 0.67 9.5 0.1 2.6 3 0 0 3 3 3 0 F pilus assembly Type-IV secretion system for plasmid transfer DUF3349 PF11829.8 OAJ15327.1 - 0.26 12.1 1.1 8.1 7.3 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) DUF4164 PF13747.6 OAJ15327.1 - 0.31 11.4 11.8 0.074 13.3 6.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) LEA_4 PF02987.16 OAJ15327.1 - 0.31 11.2 17.2 0.056 13.5 0.9 4.6 3 0 0 3 3 3 0 Late embryogenesis abundant protein Bep_C_terminal PF17841.1 OAJ15327.1 - 3.9 7.8 10.3 9.9 6.5 0.5 5.0 4 0 0 4 4 4 0 BID domain of Bartonella effector protein (Bep) Kinesin PF00225.23 OAJ15328.1 - 3e-91 305.8 0.0 4.7e-91 305.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ15328.1 - 1.4e-21 77.0 0.0 3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding KLRAQ PF10205.9 OAJ15328.1 - 0.084 13.1 1.9 0.22 11.8 0.0 2.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein FlgN PF05130.12 OAJ15328.1 - 1.2 9.6 5.9 2.7 8.5 0.2 2.5 2 0 0 2 2 2 0 FlgN protein ArAE_2 PF10334.9 OAJ15344.1 - 7.7e-45 153.5 0.1 1.3e-44 152.7 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 OAJ15344.1 - 1.2e-42 146.6 2.7 1.7e-41 142.8 2.7 2.4 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAJ15344.1 - 6e-06 26.4 29.2 8e-05 22.8 15.2 3.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like EpuA PF11772.8 OAJ15344.1 - 0.077 12.7 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta AATF-Che1 PF13339.6 OAJ15344.1 - 0.12 13.0 2.1 0.21 12.3 1.2 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor C2 PF00168.30 OAJ15345.1 - 6.8e-22 77.7 0.1 3.8e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain DDE_Tnp_1_6 PF13751.6 OAJ15345.1 - 0.2 11.9 0.4 0.49 10.6 0.4 1.6 1 0 0 1 1 1 0 Transposase DDE domain Herpes_capsid PF06112.11 OAJ15346.1 - 0.084 12.9 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein T3SSipB PF16535.5 OAJ15348.1 - 0.0015 19.0 1.2 0.0047 17.4 1.2 1.8 1 0 0 1 1 1 1 Type III cell invasion protein SipB SDA1 PF05285.12 OAJ15348.1 - 0.07 12.6 26.3 0.13 11.6 26.3 1.5 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 OAJ15348.1 - 0.27 11.3 28.6 0.53 10.4 28.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 OAJ15348.1 - 0.74 8.3 16.7 1.1 7.7 16.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 OAJ15348.1 - 0.76 8.0 20.5 1.1 7.5 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein KxDL PF10241.9 OAJ15348.1 - 0.92 9.8 7.9 2.1 8.7 7.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DNA_pol_phi PF04931.13 OAJ15348.1 - 3.2 5.8 25.7 5.5 5.0 25.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi ADIP PF11559.8 OAJ15348.1 - 3.5 7.7 21.0 0.027 14.6 11.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4218 PF13960.6 OAJ15369.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) UPRTase PF14681.6 OAJ15370.1 - 0.077 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF4055 PF13264.6 OAJ15370.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) ARGLU PF15346.6 OAJ15370.1 - 0.87 9.4 19.3 0.063 13.2 12.0 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 RVT_1 PF00078.27 OAJ15374.1 - 3.8e-27 95.3 0.0 5.5e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OrgA_MxiK PF09482.10 OAJ15375.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) Dimer_Tnp_hAT PF05699.14 OAJ15376.1 - 3.1e-13 49.3 0.0 9.3e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ15376.1 - 0.0072 16.7 0.0 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Pkinase PF00069.25 OAJ15377.1 - 4.1e-41 141.1 0.0 5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15377.1 - 9.8e-17 61.1 0.0 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ15377.1 - 1.6e-06 27.7 0.0 3.8e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAJ15377.1 - 0.0009 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TrkH PF02386.16 OAJ15398.1 - 9.8e-105 350.9 11.6 2e-103 346.6 2.3 2.1 2 0 0 2 2 2 2 Cation transport protein SRP-alpha_N PF04086.13 OAJ15398.1 - 0.048 13.6 5.2 0.11 12.4 5.2 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TB2_DP1_HVA22 PF03134.19 OAJ15398.1 - 9 6.3 10.7 0.17 11.8 2.3 2.6 2 1 0 2 2 2 0 TB2/DP1, HVA22 family ANAPC_CDC26 PF10471.9 OAJ15399.1 - 9.7e-05 23.1 10.3 0.0008 20.2 10.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 MHYT PF03707.16 OAJ15400.1 - 2.2e-19 69.4 19.1 3.4e-07 30.3 1.2 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Fis1_TPR_C PF14853.6 OAJ15401.1 - 7e-24 83.7 0.3 1.1e-23 83.1 0.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAJ15401.1 - 2.4e-13 49.5 0.0 4.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 OAJ15401.1 - 0.001 19.0 0.5 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ15401.1 - 0.038 14.6 1.1 0.13 13.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ15401.1 - 0.079 13.5 1.5 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ15401.1 - 0.53 10.2 2.5 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ESCRT-II PF05871.12 OAJ15402.1 - 9.2e-49 165.3 0.0 9.2e-48 162.1 0.0 2.0 1 1 1 2 2 2 2 ESCRT-II complex subunit SelB-wing_2 PF09106.11 OAJ15402.1 - 0.043 14.0 0.0 9.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix ORMDL PF04061.14 OAJ15403.1 - 8.2e-07 28.9 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 ORMDL family HSP70 PF00012.20 OAJ15403.1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein UPF0016 PF01169.19 OAJ15404.1 - 6e-42 141.9 26.8 4.7e-21 74.9 7.7 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.31 OAJ15404.1 - 0.016 14.5 0.1 0.016 14.5 0.1 2.0 2 0 0 2 2 2 0 Ion transport protein MttA_Hcf106 PF02416.16 OAJ15404.1 - 0.15 11.4 1.0 20 4.6 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family Bac_export_2 PF01312.19 OAJ15404.1 - 0.19 10.9 4.1 0.055 12.7 0.4 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family CobD_Cbib PF03186.13 OAJ15404.1 - 0.48 9.6 4.3 0.21 10.8 0.3 2.0 2 0 0 2 2 2 0 CobD/Cbib protein EF-hand_1 PF00036.32 OAJ15406.1 - 2.9e-20 70.2 0.0 5e-06 25.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OAJ15406.1 - 1.8e-19 68.0 0.3 5.2e-07 29.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAJ15406.1 - 1.1e-15 56.2 0.4 0.00093 18.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OAJ15406.1 - 1.7e-15 57.2 0.0 1.7e-06 28.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OAJ15406.1 - 4.4e-09 36.1 1.1 7.8e-05 22.5 0.0 3.5 3 2 1 4 4 4 3 EF-hand domain pair AT_hook PF02178.19 OAJ15426.1 - 8.6 6.6 10.1 0.58 10.2 2.4 3.0 2 0 0 2 2 2 0 AT hook motif MCM_lid PF17855.1 OAJ15427.1 - 0.11 13.0 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 MCM AAA-lid domain KDZ PF18758.1 OAJ15428.1 - 1.7e-06 27.8 0.2 2.3e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Striatin PF08232.12 OAJ15429.1 - 0.0037 17.9 1.0 0.0037 17.9 1.0 2.7 3 0 0 3 3 3 1 Striatin family Mito_carr PF00153.27 OAJ15430.1 - 2.7e-63 209.9 0.6 1.6e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhomboid PF01694.22 OAJ15431.1 - 2.4e-08 34.1 14.7 0.00057 19.9 0.8 2.7 2 1 0 2 2 2 2 Rhomboid family DDE_3 PF13358.6 OAJ15432.1 - 2.2e-17 63.2 0.0 3.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ15432.1 - 0.00061 20.3 1.0 0.0021 18.6 0.5 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ15432.1 - 0.069 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix rve PF00665.26 OAJ15434.1 - 2.4e-13 50.3 0.0 7.8e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ15434.1 - 5.6e-10 39.2 0.7 1.8e-09 37.6 0.8 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ15434.1 - 0.0026 17.5 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF2268 PF10026.9 OAJ15434.1 - 0.023 14.3 0.7 0.045 13.3 0.7 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RVT_1 PF00078.27 OAJ15435.1 - 1.3e-22 80.4 0.0 2.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ15435.1 - 0.0015 18.6 0.1 0.0073 16.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF2543 PF10820.8 OAJ15454.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) tRNA-synt_His PF13393.6 OAJ15454.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase CDC48_2 PF02933.17 OAJ15455.1 - 0.02 14.7 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 LPD5 PF18799.1 OAJ15457.1 - 0.035 14.5 1.6 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 RVT_1 PF00078.27 OAJ15458.1 - 7.1e-26 91.1 0.0 4.9e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ15458.1 - 1.1e-22 80.0 0.3 1.9e-13 50.3 0.1 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ15458.1 - 1.2e-16 60.9 0.0 1.2e-11 44.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ15458.1 - 3.6e-11 43.0 0.0 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ15458.1 - 3e-10 40.3 0.0 1e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ15458.1 - 0.007 17.0 0.0 0.028 15.0 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OAJ15458.1 - 0.028 14.7 0.0 0.091 13.1 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase_Tyr PF07714.17 OAJ15477.1 - 6e-47 160.1 0.0 8.1e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAJ15477.1 - 2.5e-45 154.9 0.0 3.8e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OAJ15477.1 - 0.0073 15.3 0.1 0.023 13.7 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ15477.1 - 0.051 12.3 4.1 0.081 11.7 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase DUF4637 PF15470.6 OAJ15477.1 - 0.89 9.3 18.8 2.3 7.9 6.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) TLP-20 PF06088.11 OAJ15477.1 - 5.3 6.9 8.3 0.27 11.1 0.3 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PX PF00787.24 OAJ15478.1 - 4.6e-13 49.1 0.0 9e-13 48.2 0.0 1.5 1 1 0 1 1 1 1 PX domain adh_short PF00106.25 OAJ15479.1 - 2.4e-87 291.4 18.0 9.4e-44 149.2 5.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ15479.1 - 4.2e-70 235.9 21.3 4.7e-35 121.2 7.1 2.7 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAJ15479.1 - 9.9e-30 102.6 0.0 2.2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 OAJ15479.1 - 3.1e-28 98.9 10.8 7e-14 52.1 2.3 2.2 2 0 0 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.19 OAJ15479.1 - 3e-06 26.7 2.1 0.034 13.5 0.1 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MaoC_dehydrat_N PF13452.6 OAJ15479.1 - 7.8e-05 22.8 0.0 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 OAJ15479.1 - 0.00017 20.9 0.6 0.12 11.7 0.3 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OAJ15479.1 - 0.00081 19.3 8.5 0.047 13.6 1.4 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 OAJ15479.1 - 0.097 12.7 4.5 1.4 8.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) AdoHcyase_NAD PF00670.21 OAJ15479.1 - 0.4 10.7 5.0 0.63 10.1 0.4 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PglL_A PF15864.5 OAJ15479.1 - 2.3 8.0 8.2 10 6.0 1.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase Spt5_N PF11942.8 OAJ15480.1 - 3.4 8.7 7.9 1.1 10.2 2.0 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Bd3614_N PF14442.6 OAJ15480.1 - 7.9 6.9 6.5 0.75 10.1 0.3 2.5 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal SUR7 PF06687.12 OAJ15481.1 - 3.4e-16 59.5 13.4 4.5e-16 59.1 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4763 PF15960.5 OAJ15481.1 - 0.22 10.8 0.4 0.31 10.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) JAB PF01398.21 OAJ15482.1 - 3.5e-16 59.2 0.0 3.3e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAJ15482.1 - 3.6e-13 49.9 0.1 6.3e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function INCA1 PF15142.6 OAJ15483.1 - 0.0062 16.6 2.4 0.49 10.4 0.0 2.9 2 1 1 3 3 3 2 INCA1 YL1 PF05764.13 OAJ15483.1 - 8.3 6.4 9.8 5.2 7.1 1.7 2.6 2 1 0 2 2 2 0 YL1 nuclear protein Bap31 PF05529.12 OAJ15484.1 - 2.4e-44 150.5 10.9 2.4e-44 150.5 10.9 1.4 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAJ15484.1 - 0.00021 21.2 7.4 0.00035 20.5 7.4 1.5 1 1 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HMG_box PF00505.19 OAJ15484.1 - 0.22 12.0 1.8 0.4 11.1 1.8 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box LSM PF01423.22 OAJ15485.1 - 9.7e-22 76.4 0.4 1.1e-21 76.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ15485.1 - 0.009 16.1 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Got1 PF04178.12 OAJ15501.1 - 7.1e-27 94.1 13.4 1e-26 93.5 13.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Acyl_transf_3 PF01757.22 OAJ15501.1 - 0.18 10.8 18.5 0.23 10.5 18.5 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF2070 PF09843.9 OAJ15501.1 - 0.3 9.3 8.0 0.33 9.2 8.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATP_sub_h PF10775.9 OAJ15502.1 - 1.8e-23 82.3 1.3 2.8e-23 81.7 1.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h HTH_13 PF11972.8 OAJ15502.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain IATP PF04568.12 OAJ15503.1 - 1.2e-12 48.1 0.2 1.4e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP MULE PF10551.9 OAJ15505.1 - 6.4e-05 23.3 0.0 0.00022 21.6 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 OAJ15505.1 - 0.0033 17.1 0.1 0.0092 15.6 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger RTA1 PF04479.13 OAJ15506.1 - 3.3e-47 160.8 6.0 2.9e-36 125.0 0.3 2.4 3 0 0 3 3 3 2 RTA1 like protein TMEM237 PF15383.6 OAJ15506.1 - 0.35 9.9 0.9 0.72 8.9 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 SF3b10 PF07189.11 OAJ15510.1 - 2.5e-32 110.8 0.0 2.8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Metallophos PF00149.28 OAJ15511.1 - 0.013 16.0 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Band_3_cyto PF07565.13 OAJ15530.1 - 0.37 10.6 4.5 0.63 9.8 0.8 2.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain BTB PF00651.31 OAJ15531.1 - 1.5e-14 54.2 0.2 1.4e-09 38.2 0.0 3.7 4 0 0 4 4 4 3 BTB/POZ domain CAP_GLY PF01302.25 OAJ15531.1 - 3.2e-07 30.2 0.7 1.7e-06 27.9 0.1 2.5 3 0 0 3 3 3 1 CAP-Gly domain Pkinase PF00069.25 OAJ15532.1 - 7.8e-77 258.2 0.1 1.1e-76 257.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15532.1 - 2.3e-41 141.8 0.0 3.8e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OAJ15532.1 - 2.8e-21 75.5 0.0 4.6e-09 36.3 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OAJ15532.1 - 1.6e-08 34.2 0.0 3.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ15532.1 - 0.0022 16.8 0.0 0.0043 15.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ15532.1 - 0.004 16.2 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ15532.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ15532.1 - 0.87 9.5 3.6 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family TP6A_N PF04406.14 OAJ15533.1 - 6.5e-16 58.1 0.0 4.7e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Type IIB DNA topoisomerase zf-UBR PF02207.20 OAJ15534.1 - 6.4e-12 45.5 11.1 6.4e-12 45.5 11.1 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 OAJ15534.1 - 0.0005 19.9 2.9 0.0005 19.9 2.9 3.2 3 0 0 3 3 3 1 PHD-finger Zf_RING PF16744.5 OAJ15534.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger RRM_1 PF00076.22 OAJ15535.1 - 9e-05 22.2 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helitron_like_N PF14214.6 OAJ15553.1 - 9.7e-18 65.1 0.1 3e-17 63.5 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ15553.1 - 2.3e-06 27.1 0.0 7.3e-06 25.4 0.0 1.7 1 1 0 2 2 2 1 PIF1-like helicase PLC-beta_C PF08703.10 OAJ15554.1 - 0.054 13.5 8.9 0.036 14.0 7.0 1.6 1 1 1 2 2 2 0 PLC-beta C terminal DUF4778 PF16008.5 OAJ15554.1 - 0.056 13.5 5.2 0.07 13.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Apolipoprotein PF01442.18 OAJ15554.1 - 0.12 12.3 18.4 0.18 11.6 18.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Muted PF14942.6 OAJ15554.1 - 0.5 10.7 12.0 0.51 10.7 10.3 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 OAJ15554.1 - 1 8.9 8.6 1.5 8.3 8.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TerB_C PF15615.6 OAJ15554.1 - 2 8.7 9.5 3.1 8.1 9.5 1.3 1 0 0 1 1 1 0 TerB-C domain Dimer_Tnp_hAT PF05699.14 OAJ15555.1 - 3.9e-08 33.0 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAJ15556.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Macoilin PF09726.9 OAJ15556.1 - 0.64 8.5 11.2 0.95 7.9 11.2 1.2 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 OAJ15556.1 - 3.7 6.4 8.2 6 5.7 8.2 1.3 1 0 0 1 1 1 0 Mitoguardin Dimer_Tnp_hAT PF05699.14 OAJ15558.1 - 1.7e-08 34.1 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAJ15559.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Macoilin PF09726.9 OAJ15559.1 - 0.64 8.5 11.2 0.95 7.9 11.2 1.2 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 OAJ15559.1 - 3.7 6.4 8.2 6 5.7 8.2 1.3 1 0 0 1 1 1 0 Mitoguardin Zn_clus PF00172.18 OAJ15576.1 - 2.8e-08 33.7 12.6 4.5e-08 33.1 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hid1 PF12722.7 OAJ15577.1 - 1.5e-125 420.3 0.0 1.5e-123 413.7 0.0 2.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAJ15577.1 - 4.1e-60 203.9 0.0 5.9e-59 200.1 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein UPF0139 PF03669.13 OAJ15578.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Spike_torovirin PF17072.5 OAJ15578.1 - 0.05 10.8 0.0 0.06 10.5 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein DUF3446 PF11928.8 OAJ15578.1 - 0.11 12.8 0.4 0.11 12.8 0.4 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Mpv17_PMP22 PF04117.12 OAJ15579.1 - 8.3e-24 83.6 0.6 1.2e-23 83.0 0.6 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3864 PF12980.7 OAJ15581.1 - 0.026 14.8 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) C5-epim_C PF06662.13 OAJ15581.1 - 0.091 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus zf-4CXXC_R1 PF10497.9 OAJ15582.1 - 7.2e-08 32.6 10.9 1.6e-07 31.5 10.9 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 K_channel_TID PF07941.11 OAJ15582.1 - 0.0077 16.7 9.7 0.0077 16.7 9.7 8.2 9 1 0 9 9 9 1 Potassium channel Kv1.4 tandem inactivation domain FYVE_2 PF02318.16 OAJ15582.1 - 0.41 10.9 4.5 0.92 9.7 4.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Rotamase_2 PF13145.6 OAJ15582.1 - 0.59 11.0 7.1 4.9 8.0 0.5 2.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain SF-assemblin PF06705.11 OAJ15583.1 - 0.0047 16.3 0.2 0.0056 16.1 0.2 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.18 OAJ15583.1 - 0.0064 16.4 3.8 0.0097 15.8 3.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OAJ15583.1 - 0.27 11.3 6.7 6.7 6.7 6.7 2.1 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4366 PF14283.6 OAJ15583.1 - 3.1 7.8 7.4 0.44 10.6 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) V-ATPase_G_2 PF16999.5 OAJ15583.1 - 3.4 8.1 14.0 9.8 6.7 1.3 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Flot PF15975.5 OAJ15583.1 - 4.3 7.5 11.5 4 7.6 0.5 2.4 2 0 0 2 2 2 0 Flotillin Tox-WTIP PF15654.6 OAJ15583.1 - 7.1 7.1 5.5 2.9 8.4 0.4 2.4 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif Flavoprotein PF02441.19 OAJ15606.1 - 9e-49 165.3 0.0 1.1e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Velvet PF11754.8 OAJ15607.1 - 3.5e-33 115.6 0.3 1.7e-19 70.7 0.1 3.5 2 2 1 3 3 3 2 Velvet factor Velvet PF11754.8 OAJ15609.1 - 6.2e-28 98.4 0.2 7.6e-28 98.1 0.2 1.0 1 0 0 1 1 1 1 Velvet factor FAM199X PF15814.5 OAJ15609.1 - 0.97 8.4 4.0 1.5 7.8 4.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X TPR_11 PF13414.6 OAJ15611.1 - 2.8e-19 68.5 2.3 6.6e-05 22.5 0.0 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.28 OAJ15611.1 - 1.3e-18 66.0 2.5 1.9e-06 27.4 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ15611.1 - 6.2e-18 63.4 3.5 1.8e-05 24.5 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ15611.1 - 6.2e-13 49.2 11.3 1.3e-08 35.3 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ15611.1 - 9e-13 48.5 0.3 1.6e-05 25.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ15611.1 - 1.7e-12 46.5 3.5 0.0088 16.2 0.2 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ15611.1 - 3.9e-09 36.2 0.1 0.18 12.3 0.0 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ15611.1 - 4e-09 36.5 0.7 0.00034 21.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ15611.1 - 7.4e-09 35.8 6.7 0.025 14.9 0.6 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ15611.1 - 8.2e-09 35.6 14.3 0.32 11.9 0.7 6.2 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ15611.1 - 0.00012 21.9 0.8 1.5 9.0 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ15611.1 - 0.00015 21.9 0.0 0.081 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 OAJ15611.1 - 0.00037 20.3 2.4 0.17 11.5 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 OAJ15611.1 - 0.00064 19.9 3.5 0.0015 18.7 0.0 2.7 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAJ15611.1 - 0.0031 16.8 0.3 0.0054 16.0 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ15611.1 - 0.0033 17.2 1.7 2.4 8.1 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 OAJ15611.1 - 0.0089 16.3 2.0 0.027 14.7 1.2 2.1 2 0 0 2 2 2 1 Tetratrico peptide repeat HSCB_C PF07743.13 OAJ15611.1 - 0.039 14.5 7.3 0.041 14.4 4.5 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain T7SS_ESX_EspC PF10824.8 OAJ15611.1 - 0.34 11.4 7.2 0.062 13.8 1.1 2.5 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Metal_resist PF13801.6 OAJ15612.1 - 0.026 14.7 1.8 0.047 13.9 1.8 1.4 1 0 0 1 1 1 0 Heavy-metal resistance DIM PF08194.12 OAJ15612.1 - 0.17 12.2 0.2 0.33 11.2 0.2 1.5 1 0 0 1 1 1 0 DIM protein RTC4 PF14474.6 OAJ15613.1 - 5.8e-12 45.8 0.0 1.4e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 RTC4-like domain Med11 PF10280.9 OAJ15614.1 - 1.7e-07 31.8 0.0 2.7e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Mediator complex protein BLM10_N PF16547.5 OAJ15637.1 - 0.00012 22.3 1.9 0.00014 22.1 1.2 1.6 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal ArAE_2_N PF10337.9 OAJ15637.1 - 0.0051 15.9 1.4 0.0059 15.7 1.4 1.0 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal Nop14 PF04147.12 OAJ15637.1 - 0.038 12.2 17.3 0.042 12.1 17.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4407 PF14362.6 OAJ15637.1 - 0.37 10.1 4.2 0.51 9.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.8 OAJ15637.1 - 0.45 9.4 8.7 0.46 9.3 8.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_11 PF13086.6 OAJ15637.1 - 0.48 10.2 5.0 0.6 9.8 5.0 1.1 1 0 0 1 1 1 0 AAA domain RRN3 PF05327.11 OAJ15637.1 - 2.2 6.7 8.3 2.6 6.5 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cpn60_TCP1 PF00118.24 OAJ15638.1 - 1.7e-143 478.8 8.7 1.9e-143 478.6 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAJ15638.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Glycogen_syn PF05693.13 OAJ15638.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase SLX9 PF15341.6 OAJ15639.1 - 1.4e-17 64.3 3.9 2.7e-17 63.4 3.9 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Zn_clus PF00172.18 OAJ15640.1 - 7.1e-07 29.3 3.8 1.2e-06 28.6 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ15640.1 - 0.0022 17.0 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2722 PF10846.8 OAJ15640.1 - 0.033 13.1 9.9 0.062 12.2 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 OAJ15640.1 - 0.036 13.1 4.4 0.054 12.5 4.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 OAJ15640.1 - 0.049 14.6 0.6 0.14 13.1 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 OAJ15640.1 - 0.64 10.4 4.9 0.45 10.9 0.8 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RAB3GAP2_N PF14655.6 OAJ15640.1 - 1.9 7.7 3.8 3.1 7.0 3.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 OAJ15640.1 - 2.1 7.9 26.3 0.14 11.7 17.3 2.4 2 0 0 2 2 2 0 Spt20 family DUF5421 PF17458.2 OAJ15640.1 - 5.5 6.3 7.9 8.5 5.7 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) TraI PF07057.11 OAJ15641.1 - 0.093 12.9 0.9 0.11 12.6 0.9 1.1 1 0 0 1 1 1 0 DNA helicase TraI Mito_carr PF00153.27 OAJ15642.1 - 4.7e-47 157.9 4.4 1.2e-14 54.0 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein Lipase_3 PF01764.25 OAJ15643.1 - 7.8e-12 45.3 0.0 8.5e-10 38.7 0.1 2.6 2 0 0 2 2 2 2 Lipase (class 3) PsaL PF02605.15 OAJ15643.1 - 0.0025 17.5 0.1 0.0079 15.9 0.0 1.8 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI DPBB_1 PF03330.18 OAJ15644.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ15644.1 - 0.0018 18.1 0.3 0.0031 17.3 0.3 1.3 1 0 0 1 1 1 1 Barwin family DSBA PF01323.20 OAJ15646.1 - 2.9e-21 76.2 0.0 3.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Hyr1 PF15789.5 OAJ15646.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.2 2 1 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 DUF202 PF02656.15 OAJ15663.1 - 1e-06 29.1 7.0 1e-06 29.1 7.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF202) 5-nucleotidase PF06189.12 OAJ15664.1 - 0.072 12.0 0.1 0.077 11.9 0.1 1.0 1 0 0 1 1 1 0 5'-nucleotidase EVE PF01878.18 OAJ15665.1 - 3.3e-40 137.4 0.0 1.1e-39 135.8 0.0 1.8 1 1 0 1 1 1 1 EVE domain Nipped-B_C PF12830.7 OAJ15666.1 - 2.6e-49 167.7 1.4 2.6e-49 167.7 1.4 3.0 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OAJ15666.1 - 1.9e-08 34.5 1.5 2.4e-06 27.7 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 OAJ15666.1 - 8.9e-08 32.4 9.5 0.99 9.8 0.1 6.0 4 0 0 4 4 4 4 HEAT repeats Cnd1 PF12717.7 OAJ15666.1 - 2.6e-05 24.3 1.1 0.00011 22.2 0.8 2.4 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ15666.1 - 0.0047 15.5 4.1 1.7 7.1 0.1 3.6 2 2 1 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ15666.1 - 0.59 10.7 8.7 0.47 11.0 2.2 3.9 3 0 0 3 3 3 0 HEAT-like repeat Peptidase_S26 PF10502.9 OAJ15667.1 - 2.6e-07 30.5 0.0 5.4e-05 23.0 0.0 3.1 3 1 0 3 3 3 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OAJ15667.1 - 0.00074 19.4 0.0 0.0032 17.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Cut8 PF08559.10 OAJ15668.1 - 1.2e-12 47.9 0.0 3.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein 6PF2K PF01591.18 OAJ15670.1 - 2.2e-63 213.5 0.0 3.1e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAJ15670.1 - 8e-22 77.9 0.3 1.5e-19 70.5 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAJ15670.1 - 0.00019 21.6 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ15670.1 - 0.0052 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 HMG_box PF00505.19 OAJ15671.1 - 3.2e-08 33.9 1.3 0.00019 21.8 0.4 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box QRPTase_C PF01729.19 OAJ15695.1 - 4.5e-42 143.7 0.5 1.5e-40 138.7 0.5 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAJ15695.1 - 2.1e-17 63.0 0.2 7.7e-16 57.9 0.1 2.8 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.20 OAJ15695.1 - 0.089 12.1 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 LysR substrate binding domain IMUP PF15761.5 OAJ15695.1 - 0.14 12.8 4.0 0.33 11.7 4.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 OAJ15695.1 - 2.8 7.5 7.8 4.2 6.9 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lung_7-TM_R PF06814.13 OAJ15696.1 - 1.3e-50 172.4 19.1 2.1e-50 171.7 19.1 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor Tub_N PF16322.5 OAJ15696.1 - 0.09 13.2 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Tubby N-terminal DUF3671 PF12420.8 OAJ15696.1 - 0.17 11.9 2.9 0.61 10.2 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function PepSY_TM PF03929.16 OAJ15696.1 - 0.34 10.6 13.7 0.28 10.8 9.4 2.8 2 1 1 3 3 3 0 PepSY-associated TM region YlaC PF10777.9 OAJ15696.1 - 0.53 10.1 8.3 0.58 10.0 3.1 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC WD40 PF00400.32 OAJ15697.1 - 9.5e-12 45.3 16.7 0.00015 22.4 0.2 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Es2 PF09751.9 OAJ15698.1 - 2.6e-72 244.9 19.0 1.6e-70 239.0 19.0 2.3 1 1 0 1 1 1 1 Nuclear protein Es2 Proteasome PF00227.26 OAJ15699.1 - 3.7e-16 59.2 0.0 6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit KilA-N PF04383.13 OAJ15700.1 - 0.001 18.9 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 2 KilA-N domain SAM_2 PF07647.17 OAJ15700.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LIP PF03583.14 OAJ15701.1 - 2.6e-39 135.3 0.3 1.1e-37 129.9 0.3 2.1 1 1 0 1 1 1 1 Secretory lipase Proteasome PF00227.26 OAJ15702.1 - 9e-44 149.2 0.0 1.4e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ15702.1 - 1e-08 34.7 0.4 1e-08 34.7 0.4 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ADH_N PF08240.12 OAJ15722.1 - 8.3e-28 96.4 2.9 1.4e-27 95.7 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ15722.1 - 7.8e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ15722.1 - 0.015 14.7 0.2 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAJ15722.1 - 0.029 15.4 0.0 0.056 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NTP_transferase PF00483.23 OAJ15723.1 - 1.6e-07 31.1 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OAJ15723.1 - 0.00028 21.3 0.3 0.00079 19.8 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain PMT PF02366.18 OAJ15724.1 - 2.1e-75 253.5 12.0 4.2e-75 252.5 12.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ15724.1 - 9.9e-64 214.6 17.9 9.9e-64 214.6 17.9 2.4 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ15724.1 - 1.8e-37 129.0 0.0 5.3e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 MIR domain OppC_N PF12911.7 OAJ15724.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C zf-RING_2 PF13639.6 OAJ15725.1 - 2.9e-09 37.1 10.8 1.7e-07 31.5 1.6 3.7 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ15725.1 - 9e-06 25.6 0.4 0.0027 17.7 0.0 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ15725.1 - 0.00012 21.8 5.6 0.012 15.4 0.7 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ15725.1 - 0.0002 21.3 2.0 0.0039 17.2 0.8 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OAJ15725.1 - 0.00021 21.2 3.8 0.016 15.1 0.4 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAJ15725.1 - 0.00038 20.7 12.0 0.00039 20.6 2.9 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAJ15725.1 - 0.041 13.6 6.3 7.1 6.5 0.0 3.4 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 OAJ15725.1 - 0.42 10.5 6.8 0.22 11.4 1.1 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAJ15725.1 - 0.47 10.4 11.6 0.38 10.7 1.6 3.6 4 1 0 4 4 4 0 PHD-finger Zn_ribbon_17 PF17120.5 OAJ15725.1 - 1.4 8.6 7.5 0.22 11.2 1.4 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-4CXXC_R1 PF10497.9 OAJ15725.1 - 2 8.7 4.5 6.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_4 PF14570.6 OAJ15725.1 - 2.4 8.0 5.1 43 4.0 0.2 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 OAJ15725.1 - 2.7 7.9 12.0 2.6 8.0 0.9 3.3 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ15725.1 - 7.2 6.6 12.1 0.28 11.1 0.2 3.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 SPA PF08616.10 OAJ15726.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Avl9 PF09794.9 OAJ15726.1 - 0.16 10.6 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 FA_hydroxylase PF04116.13 OAJ15727.1 - 1.1e-17 64.7 7.5 1.1e-17 64.7 7.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fes1 PF08609.10 OAJ15729.1 - 1.1e-18 67.9 0.9 1.9e-16 60.7 0.2 3.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 OAJ15729.1 - 6.8e-05 22.8 3.5 2.3 8.7 0.0 5.0 4 1 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 OAJ15729.1 - 0.0092 14.6 0.1 0.67 8.4 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ15729.1 - 3.3 8.3 9.1 20 5.8 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat Thioredoxin PF00085.20 OAJ15730.1 - 6.3e-26 90.4 0.0 8.3e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ15730.1 - 1.7e-07 31.6 0.1 1e-06 29.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ15730.1 - 2.9e-06 27.5 0.0 7.1e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ15730.1 - 6.3e-06 26.3 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OAJ15730.1 - 8.1e-05 22.4 0.3 0.016 14.9 0.1 2.1 1 1 1 2 2 2 2 Redoxin DIM1 PF02966.16 OAJ15730.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 OST3_OST6 PF04756.13 OAJ15730.1 - 0.00023 20.6 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAJ15730.1 - 0.00026 20.9 0.1 0.00073 19.5 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OAJ15730.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 OAJ15730.1 - 0.046 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 OAJ15730.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein YfzA PF14118.6 OAJ15731.1 - 0.35 11.3 2.7 20 5.7 0.4 2.7 2 0 0 2 2 2 0 YfzA-like protein DUF4083 PF13314.6 OAJ15731.1 - 1.6 8.7 9.2 12 6.0 0.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) Methyltransf_16 PF10294.9 OAJ15751.1 - 4.7e-22 78.5 0.0 9.6e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Glyco_hydro_5_C PF18564.1 OAJ15752.1 - 6.7e-09 36.2 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAJ15752.1 - 0.014 14.8 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) HSP70 PF00012.20 OAJ15753.1 - 1.3e-27 96.3 0.1 2e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein RNA_pol_I_A49 PF06870.12 OAJ15753.1 - 3.5e-11 42.6 0.1 5.4e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_U40 PF10464.9 OAJ15753.1 - 0.057 13.1 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase U40 AMP-binding PF00501.28 OAJ15754.1 - 4.4e-77 259.5 0.0 7.7e-77 258.7 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme DUF2462 PF09495.10 OAJ15755.1 - 1e-15 58.2 9.2 1e-15 58.2 9.2 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) DUF2868 PF11067.8 OAJ15755.1 - 0.33 10.4 2.9 0.35 10.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TauD PF02668.16 OAJ15757.1 - 7.9e-43 147.2 0.1 1.6e-42 146.2 0.1 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RT_RNaseH PF17917.1 OAJ15758.1 - 4e-11 43.1 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ15758.1 - 3.9e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAS_I_H PF18314.1 OAJ15759.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain ANAPC1 PF12859.7 OAJ15781.1 - 2.9e-11 44.0 2.8 2.9e-11 44.0 2.8 2.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 OAJ15781.1 - 0.0003 21.0 7.0 5.6 7.6 0.0 5.6 5 0 0 5 5 5 3 Proteasome/cyclosome repeat RNA_pol_L_2 PF13656.6 OAJ15783.1 - 8.1e-28 96.0 0.0 1.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ15783.1 - 7.7e-08 31.7 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ANAPC5 PF12862.7 OAJ15784.1 - 2e-14 53.4 1.4 6e-14 51.9 1.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 UvsW PF11637.8 OAJ15784.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW TPR_12 PF13424.6 OAJ15784.1 - 0.24 11.7 3.0 1.8 8.9 1.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ15784.1 - 3 8.2 4.1 20 5.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 OAJ15786.1 - 1e-16 61.0 14.4 0.0014 19.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15786.1 - 6.1e-10 39.3 0.0 0.14 12.5 0.0 5.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ15786.1 - 3.2e-06 26.4 0.3 1.6e-05 24.1 0.2 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PAP_assoc PF03828.19 OAJ15787.1 - 2.4e-15 56.5 0.1 4.8e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAJ15787.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ15787.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase BRCA-2_OB1 PF09103.10 OAJ15806.1 - 2.4e-32 111.5 0.0 3.9e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 OAJ15806.1 - 1.3e-07 31.5 0.1 2.4e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.18 OAJ15806.1 - 0.0092 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 BRCA2 repeat 2-Hacid_dh_C PF02826.19 OAJ15807.1 - 4.3e-52 176.1 0.0 7.6e-52 175.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ15807.1 - 2.2e-35 121.2 0.0 3e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAJ15807.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Aldedh PF00171.22 OAJ15808.1 - 8.5e-105 350.9 0.1 1e-104 350.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ERCC4 PF02732.15 OAJ15809.1 - 2.3e-20 73.4 0.0 4.6e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.16 OAJ15809.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Tfb2 PF03849.14 OAJ15810.1 - 3.5e-135 450.6 0.0 4.3e-135 450.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAJ15810.1 - 1.5e-23 83.0 0.6 4.4e-23 81.5 0.6 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAJ15810.1 - 0.0002 21.5 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyridox_oxase_2 PF12766.7 OAJ15812.1 - 2.6e-21 76.1 0.0 3.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NIF PF03031.18 OAJ15813.1 - 8.7e-22 77.6 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 OAJ15813.1 - 0.0082 15.9 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family HhH-GPD PF00730.25 OAJ15814.1 - 2.4e-17 63.3 0.0 3.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ15814.1 - 6.3e-08 32.1 0.0 1.8e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif cwf18 PF08315.12 OAJ15814.1 - 0.021 15.5 5.7 0.021 15.5 5.7 1.6 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor HHH_5 PF14520.6 OAJ15814.1 - 0.039 14.6 0.0 0.2 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain TAFII55_N PF04658.13 OAJ15815.1 - 7e-51 172.1 0.2 7e-51 172.1 0.2 2.2 3 0 0 3 3 3 1 TAFII55 protein conserved region SUIM_assoc PF16619.5 OAJ15815.1 - 4.9e-05 23.3 2.1 0.00037 20.5 2.1 2.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 AhpC-TSA_2 PF13911.6 OAJ15837.1 - 7.9e-15 55.0 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ15837.1 - 0.037 13.7 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Redoxin NAD_binding_7 PF13241.6 OAJ15837.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding RCC1 PF00415.18 OAJ15838.1 - 6.2e-37 126.0 5.3 7.5e-08 32.9 0.0 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ15838.1 - 7.9e-22 76.5 13.2 3.1e-05 23.6 0.0 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 OAJ15838.1 - 2.2e-10 40.3 11.0 2.2e-10 40.3 11.0 1.7 2 0 0 2 2 2 1 PHD-finger ADK_lid PF05191.14 OAJ15838.1 - 0.0075 16.2 2.1 0.03 14.3 1.3 2.3 2 0 0 2 2 2 1 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 OAJ15838.1 - 1.4 8.9 9.7 0.28 11.1 5.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 OAJ15838.1 - 1.6 8.6 11.1 0.57 10.1 5.5 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CHCH PF06747.13 OAJ15839.1 - 3.5e-06 27.0 3.9 6.4e-06 26.2 3.9 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 OAJ15839.1 - 0.018 15.5 4.1 0.034 14.6 4.1 1.5 1 0 0 1 1 1 0 GCK domain MAM33 PF02330.16 OAJ15841.1 - 1.7e-60 204.6 0.0 2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein NESP55 PF06390.12 OAJ15841.1 - 3.5 7.1 13.9 0.22 11.1 8.7 1.5 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pyridoxal_deC PF00282.19 OAJ15842.1 - 5.6e-21 74.7 0.0 8e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAJ15842.1 - 2.4e-10 39.9 0.0 4.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAJ15842.1 - 0.0084 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SAGA-Tad1 PF12767.7 OAJ15843.1 - 0.33 10.7 3.0 0.49 10.1 3.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit UPF0220 PF05255.11 OAJ15844.1 - 1.4e-50 171.1 0.0 1.7e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Glyco_transf_41 PF13844.6 OAJ15845.1 - 1.3e-101 340.4 1.3 3.2e-48 164.3 0.0 4.2 3 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 OAJ15845.1 - 5e-19 67.2 0.0 6.7e-05 22.5 0.1 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ15845.1 - 1.4e-16 59.8 1.4 8e-06 25.4 0.1 5.0 3 1 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 OAJ15845.1 - 9.8e-16 56.9 0.8 6e-05 23.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ15845.1 - 5.2e-14 51.1 0.0 0.0031 17.5 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ15845.1 - 7.1e-11 41.4 0.0 0.00049 20.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ15845.1 - 2.2e-10 40.1 9.2 0.0014 18.4 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ15845.1 - 3.3e-08 33.7 4.8 0.2 12.6 0.0 5.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ15845.1 - 1e-07 32.3 0.0 0.092 13.3 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ15845.1 - 2.6e-07 30.8 0.0 0.77 10.1 0.0 4.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ15845.1 - 8.7e-05 22.3 0.1 2 8.6 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ15845.1 - 0.0066 16.6 0.0 0.061 13.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Pkinase PF00069.25 OAJ15870.1 - 7.3e-54 182.9 0.0 1e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15870.1 - 1.2e-18 67.3 0.0 2.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAJ15870.1 - 0.0051 16.4 0.1 0.0099 15.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ15870.1 - 0.031 14.2 0.9 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ15870.1 - 0.1 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Exo_endo_phos_2 PF14529.6 OAJ15872.1 - 3.2e-16 59.2 0.0 5.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ15872.1 - 4.8e-06 26.3 1.8 1e-05 25.2 1.8 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 OAJ15872.1 - 0.65 10.2 7.6 0.044 13.9 1.9 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 OAJ15873.1 - 1.2e-25 90.4 0.0 1.7e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAJ15873.1 - 1e-10 41.9 0.0 3.6e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 RNase H SMN PF06003.12 OAJ15875.1 - 7.3 5.8 7.2 13 4.9 7.2 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Topoisom_bac PF01131.20 OAJ15893.1 - 1.8e-58 198.6 0.0 8.8e-58 196.2 0.0 1.8 1 1 0 1 1 1 1 DNA topoisomerase Pil1 PF13805.6 OAJ15894.1 - 9.7e-49 166.2 0.0 1.8e-48 165.3 0.0 1.5 1 1 0 1 1 1 1 Eisosome component PIL1 CFTR_R PF14396.6 OAJ15894.1 - 0.091 12.3 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Lzipper-MIP1 PF14389.6 OAJ15894.1 - 5 7.5 7.1 33 4.9 0.3 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Glyco_hydro_88 PF07470.13 OAJ15895.1 - 3.7e-15 55.8 0.4 3.5e-14 52.6 0.4 2.0 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 TTL PF03133.15 OAJ15897.1 - 1.9e-41 142.1 0.0 4.8e-28 98.1 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family CENP-B_dimeris PF09026.10 OAJ15897.1 - 0.0003 21.1 1.7 0.00066 20.0 1.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nro1 PF12753.7 OAJ15897.1 - 0.36 9.7 4.0 0.52 9.2 4.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF2457 PF10446.9 OAJ15897.1 - 1 8.4 6.6 1.7 7.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 OAJ15897.1 - 1.8 8.8 6.7 3.5 7.9 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 OAJ15897.1 - 3.1 5.8 8.3 5 5.1 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ15897.1 - 9.7 5.4 8.4 15 4.8 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein Sec23_trunk PF04811.15 OAJ15898.1 - 1.1e-57 195.4 0.0 3.1e-51 174.3 0.0 2.1 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAJ15898.1 - 2.3e-20 72.3 0.0 3.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAJ15898.1 - 2.8e-20 72.9 0.0 6.8e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAJ15898.1 - 1.1e-14 54.2 6.3 2.1e-14 53.3 6.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAJ15898.1 - 0.00039 20.3 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat LSM PF01423.22 OAJ15899.1 - 1e-14 54.0 0.0 1.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain TssC PF17541.2 OAJ15900.1 - 0.16 10.8 0.4 0.22 10.3 0.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DUF4461 PF14688.6 OAJ15900.1 - 0.23 11.2 1.7 0.35 10.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Topoisom_bac PF01131.20 OAJ15902.1 - 8.3e-18 64.6 0.0 1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-CCHC PF00098.23 OAJ15902.1 - 6.3e-07 29.2 4.9 1.5e-06 28.0 4.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ15902.1 - 0.056 13.4 1.8 0.11 12.5 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle MbeD_MobD PF04899.12 OAJ15902.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 MbeD/MobD like eIF3g PF12353.8 OAJ15902.1 - 0.13 12.6 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 OAJ15902.1 - 0.45 10.4 4.5 0.82 9.5 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Topoisom_bac PF01131.20 OAJ15903.1 - 5.8e-23 81.6 0.0 7.9e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OAJ15903.1 - 1.7e-19 69.9 0.0 3.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain TIP41 PF04176.13 OAJ15903.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 TIP41-like family Y_phosphatase PF00102.27 OAJ15920.1 - 4e-28 98.6 0.0 4.6e-13 49.3 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ15920.1 - 2.5e-06 27.3 0.0 5.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TAF4 PF05236.14 OAJ15921.1 - 1.9e-27 96.8 34.7 5.2e-22 78.9 9.8 4.1 2 1 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 OAJ15921.1 - 0.003 17.3 0.3 0.003 17.3 0.3 2.0 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit DPBB_1 PF03330.18 OAJ15922.1 - 0.00059 20.1 0.7 0.002 18.4 0.7 2.0 1 1 0 1 1 1 1 Lytic transglycolase SAPS PF04499.15 OAJ15923.1 - 1.1e-144 482.9 0.0 3.8e-144 481.1 0.0 1.9 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein TSP9 PF11493.8 OAJ15923.1 - 1 10.0 0.0 1 10.0 0.0 4.1 6 0 0 6 6 6 0 Thylakoid soluble phosphoprotein TSP9 HORMA PF02301.18 OAJ15924.1 - 7.2e-51 172.8 0.7 2.2e-50 171.2 0.0 2.1 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 OAJ15924.1 - 1.4e-08 34.5 4.8 2.4e-08 33.7 4.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ15924.1 - 0.0012 18.4 1.8 0.0019 17.7 1.8 1.4 1 0 0 1 1 1 1 PHD-finger Lactamase_B PF00753.27 OAJ15925.1 - 4.6e-07 30.0 1.2 0.0063 16.5 0.1 2.6 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 OAJ15925.1 - 4.7e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 OAJ15925.1 - 0.018 14.5 0.3 0.034 13.6 0.3 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.32 OAJ15926.1 - 1.9e-22 79.1 3.2 1.8e-07 31.7 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OAJ15926.1 - 0.015 13.8 0.0 0.032 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4666 PF15697.5 OAJ15926.1 - 1.2 9.8 7.8 0.14 12.8 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4666) FA_hydroxylase PF04116.13 OAJ15927.1 - 6.8e-22 78.2 16.5 6.8e-22 78.2 16.5 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HPS6 PF15702.5 OAJ15927.1 - 0.097 10.6 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein Peptidase_S8 PF00082.22 OAJ15942.1 - 1.9e-41 142.3 0.0 4.3e-41 141.1 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ15942.1 - 6.8e-09 36.4 0.0 1.7e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain Dcc1 PF09724.9 OAJ15944.1 - 9.5e-67 225.7 0.0 1.7e-66 224.9 0.0 1.4 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 UBA2_C PF16195.5 OAJ15944.1 - 0.18 12.5 3.5 0.43 11.3 0.2 2.6 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus RRM_1 PF00076.22 OAJ15946.1 - 3.3e-32 110.1 0.0 4.1e-16 58.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ15946.1 - 0.0054 16.8 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif DUF3344 PF11824.8 OAJ15946.1 - 0.0078 15.9 0.0 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3344) DUF3343 PF11823.8 OAJ15946.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Macoilin PF09726.9 OAJ15946.1 - 0.35 9.4 7.9 0.42 9.1 7.9 1.0 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 OAJ15946.1 - 1.5 6.8 7.2 1.9 6.5 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 OAJ15946.1 - 1.8 7.6 8.6 2.3 7.2 8.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 OAJ15946.1 - 4 6.2 12.8 5.3 5.8 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ArsA_ATPase PF02374.15 OAJ15948.1 - 1.8e-109 365.6 0.1 2.1e-109 365.4 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAJ15948.1 - 1.6e-11 44.4 0.2 4.4e-11 43.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OAJ15948.1 - 2.3e-10 40.6 0.0 4.2e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OAJ15948.1 - 1.9e-05 24.2 0.2 0.0003 20.3 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 OAJ15948.1 - 2.7e-05 23.8 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OAJ15948.1 - 5.3e-05 22.8 0.0 0.00013 21.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OAJ15948.1 - 0.0006 19.5 0.4 0.0053 16.4 0.2 2.2 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OAJ15948.1 - 0.0062 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 OAJ15948.1 - 0.0096 16.5 0.0 0.076 13.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ15948.1 - 0.014 15.8 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OAJ15948.1 - 0.03 14.0 0.0 0.098 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ15948.1 - 0.064 12.7 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Alba PF01918.21 OAJ15950.1 - 6.8e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Alba Pkinase PF00069.25 OAJ15969.1 - 5.3e-72 242.4 0.0 6.4e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15969.1 - 2.1e-40 138.6 0.0 2.6e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ15969.1 - 1.4e-08 33.9 0.0 2.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ15969.1 - 1.1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ15969.1 - 3.7e-06 26.4 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAJ15969.1 - 0.00065 19.3 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 OAJ15969.1 - 0.0023 17.9 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 OAJ15969.1 - 0.27 11.4 0.9 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain ABC_membrane PF00664.23 OAJ15970.1 - 1.1e-77 261.4 19.8 8.3e-43 147.0 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ15970.1 - 2.8e-50 170.4 0.1 3.5e-31 108.5 0.2 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ15970.1 - 1.2e-06 28.1 0.1 0.009 15.5 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ15970.1 - 3.1e-05 24.4 1.0 0.019 15.3 0.5 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ15970.1 - 0.0001 22.3 0.4 0.17 11.9 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ15970.1 - 0.0012 18.8 0.1 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 OAJ15970.1 - 0.0016 18.6 0.8 0.37 10.8 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 OAJ15970.1 - 0.0045 17.1 0.3 0.59 10.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.17 OAJ15970.1 - 0.013 15.3 0.4 9.1 6.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 OAJ15970.1 - 0.018 14.7 0.8 7.8 6.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OAJ15970.1 - 0.021 14.6 1.2 3 7.5 0.2 3.0 3 1 0 3 3 3 0 AAA domain T2SSE PF00437.20 OAJ15970.1 - 0.06 12.4 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 OAJ15970.1 - 0.21 10.3 0.6 1.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Helitron_like_N PF14214.6 OAJ15971.1 - 1.7e-31 109.9 0.3 2.7e-31 109.3 0.3 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ15972.1 - 7.7e-48 163.5 0.0 1.1e-47 163.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ15972.1 - 5.9e-11 42.4 0.0 9.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ15972.1 - 2.7e-08 34.3 0.0 7e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ15972.1 - 1.1e-05 25.9 0.1 0.13 12.6 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OAJ15972.1 - 0.00076 19.9 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ15972.1 - 0.00097 19.2 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OAJ15972.1 - 0.0035 17.3 0.0 0.0085 16.0 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAJ15972.1 - 0.0052 17.1 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ15972.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 OAJ15972.1 - 0.046 13.0 0.1 0.2 10.8 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 OAJ15972.1 - 0.15 12.1 0.1 0.81 9.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain NmrA PF05368.13 OAJ15973.1 - 1.6e-36 126.0 0.2 1.9e-36 125.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ15973.1 - 9.8e-18 64.7 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Cys_Met_Meta_PP PF01053.20 OAJ15973.1 - 0.002 16.7 0.3 0.01 14.4 0.1 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme 3Beta_HSD PF01073.19 OAJ15973.1 - 0.0058 15.7 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ15973.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 KR domain CIA30 PF08547.12 OAJ15974.1 - 5.6e-20 72.0 0.0 4.6e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 OAJ15974.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain DUF2439 PF10382.9 OAJ15996.1 - 3.8e-13 49.6 0.1 5.6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) AbrB_C PF18277.1 OAJ15996.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AbrB C-terminal domain TLP-20 PF06088.11 OAJ15997.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 OAJ15997.1 - 7.4 5.2 5.9 11 4.6 5.9 1.2 1 0 0 1 1 1 0 Presenilin Mito_carr PF00153.27 OAJ15998.1 - 5.7e-51 170.4 16.6 4.4e-19 68.2 0.1 4.7 5 0 0 5 5 5 4 Mitochondrial carrier protein Spt20 PF12090.8 OAJ15998.1 - 1.2 8.6 5.4 1.9 8.0 5.4 1.3 1 0 0 1 1 1 0 Spt20 family Thioredoxin PF00085.20 OAJ15999.1 - 1.8e-30 105.0 0.0 2.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ15999.1 - 1.1e-07 32.3 0.1 2.3e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OAJ15999.1 - 8e-07 28.9 0.0 9.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ15999.1 - 2.3e-06 27.9 0.0 5.6e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OAJ15999.1 - 3.1e-06 26.8 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 OAJ15999.1 - 8.6e-06 25.7 0.0 9.9e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OAJ15999.1 - 9.7e-06 25.4 0.0 2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ15999.1 - 6.1e-05 22.9 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 OAJ15999.1 - 0.0018 18.4 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 OAJ15999.1 - 0.0067 16.6 0.1 0.0096 16.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.16 OAJ15999.1 - 0.018 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_3 PF13192.6 OAJ15999.1 - 0.075 13.1 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_5 PF13743.6 OAJ15999.1 - 0.11 12.2 0.1 2.7 7.6 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin DUF2847 PF11009.8 OAJ15999.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Hira PF07569.11 OAJ16000.1 - 3.5e-35 121.7 0.0 3.3e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 TUP1-like enhancer of split WD40 PF00400.32 OAJ16000.1 - 5.7e-22 77.6 26.4 1.1e-05 26.0 1.1 7.6 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16000.1 - 1.6e-09 37.9 2.1 0.019 15.2 0.0 5.7 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAJ16000.1 - 0.00011 21.9 0.7 0.00032 20.4 0.7 1.9 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 OAJ16000.1 - 0.2 10.6 0.8 6.7 5.6 0.0 3.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAJ16000.1 - 0.49 10.4 5.5 10 6.2 0.5 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DAO PF01266.24 OAJ16001.1 - 4.6e-40 138.3 0.1 5.5e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ16001.1 - 1.2e-05 25.3 0.6 0.0026 17.8 0.0 2.5 1 1 1 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ16001.1 - 0.0013 18.9 0.2 0.0036 17.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltrans_RNA PF04452.14 OAJ16001.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 RNA methyltransferase DUF2423 PF10338.9 OAJ16002.1 - 4.8e-10 39.5 5.5 8.9e-10 38.6 5.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) DUF4743 PF15916.5 OAJ16003.1 - 1e-12 48.0 0.0 8.7e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OAJ16003.1 - 2.2e-11 43.9 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Cupin_8 PF13621.6 OAJ16004.1 - 7.8e-18 65.1 0.1 1.5e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OAJ16004.1 - 8.2e-18 64.9 0.1 8.3e-17 61.7 0.1 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase PH PF00169.29 OAJ16005.1 - 6.8e-40 135.8 1.4 1.7e-20 73.5 0.3 3.3 3 0 0 3 3 3 3 PH domain PH_3 PF14593.6 OAJ16005.1 - 9.8e-16 57.8 2.0 2.3e-07 30.8 0.4 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 OAJ16005.1 - 2.1e-13 50.6 10.7 7.1e-06 26.4 6.1 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 OAJ16005.1 - 1.4e-11 44.5 5.0 4e-07 30.2 1.3 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 OAJ16005.1 - 7.3e-07 29.6 7.6 0.0009 19.6 1.1 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.7 OAJ16005.1 - 0.0038 17.3 3.0 2.7 8.1 0.7 3.2 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology Spt20 PF12090.8 OAJ16005.1 - 0.01 15.4 8.6 0.01 15.4 8.6 3.9 3 1 0 3 3 3 0 Spt20 family PH_2 PF08458.10 OAJ16005.1 - 0.051 13.9 0.0 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_4 PF15404.6 OAJ16005.1 - 1.9 8.3 11.4 0.92 9.3 0.1 4.1 4 0 0 4 4 4 0 Pleckstrin homology domain Roughex PF06020.11 OAJ16005.1 - 4.9 6.2 12.0 0.49 9.4 1.6 2.9 2 0 0 2 2 2 0 Drosophila roughex protein Got1 PF04178.12 OAJ16006.1 - 5.6e-18 65.4 15.6 7e-18 65.1 15.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Fungal_trans PF04082.18 OAJ16028.1 - 3.1e-11 42.8 0.2 4.7e-11 42.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhomboid PF01694.22 OAJ16029.1 - 4.9e-06 26.6 2.7 9e-06 25.8 2.7 1.5 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OAJ16029.1 - 4.1e-05 24.1 2.9 4.7e-05 23.9 1.5 1.8 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 OAJ16029.1 - 6.3e-05 23.0 6.6 0.00029 20.8 2.8 2.1 2 0 0 2 2 2 1 Der1-like family DUF1631 PF07793.11 OAJ16029.1 - 0.98 7.8 2.5 1.3 7.4 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Oxidored_q2 PF00420.24 OAJ16029.1 - 1.2 8.8 5.4 0.18 11.4 1.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L HECT PF00632.25 OAJ16030.1 - 1.8e-73 247.7 0.0 2.7e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OAJ16031.1 - 1.2e-57 195.3 0.0 4.9e-31 108.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16031.1 - 1.4e-19 70.4 0.0 5.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAJ16031.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ16031.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAJ16031.1 - 0.19 11.6 3.9 0.32 10.9 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family BUD22 PF09073.10 OAJ16031.1 - 4.6 6.5 15.8 0.72 9.1 9.1 2.2 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 OAJ16031.1 - 6.6 4.9 8.2 3.3 5.9 5.6 1.8 2 0 0 2 2 2 0 CDC45-like protein PH_12 PF16457.5 OAJ16032.1 - 6.2e-32 110.9 0.0 1.4e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 OAJ16032.1 - 7.1e-26 91.4 0.0 1.1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 OAJ16032.1 - 1.2e-23 83.8 0.0 4.4e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.16 OAJ16032.1 - 0.00097 18.8 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain V-ATPase_H_N PF03224.14 OAJ16032.1 - 0.012 14.9 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 V-ATPase subunit H PHF5 PF03660.14 OAJ16033.1 - 2.4e-46 156.2 8.3 2.6e-46 156.1 8.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAJ16033.1 - 0.0053 14.7 3.8 0.0054 14.7 3.8 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 OAJ16033.1 - 0.064 13.6 1.7 0.064 13.6 1.7 2.7 2 1 0 2 2 2 0 C1 domain DZR PF12773.7 OAJ16033.1 - 1.7 8.8 14.8 1.1 9.3 1.7 2.9 1 1 1 2 2 2 0 Double zinc ribbon Nbl1_Borealin_N PF10444.9 OAJ16048.1 - 3.2e-08 33.1 0.8 5.7e-08 32.3 0.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Edc3_linker PF16598.5 OAJ16048.1 - 0.062 14.0 0.8 0.062 14.0 0.8 2.5 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 YidD PF01809.18 OAJ16050.1 - 0.052 13.4 0.7 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor GTP_CH_N PF12471.8 OAJ16051.1 - 6.3e-88 293.6 0.0 1e-87 292.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAJ16051.1 - 1.2e-15 57.5 0.0 1.8e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Arf PF00025.21 OAJ16052.1 - 1.4e-79 265.6 0.1 1.6e-79 265.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAJ16052.1 - 1.8e-14 54.0 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ16052.1 - 4.5e-14 52.3 0.0 5.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAJ16052.1 - 2e-13 50.2 0.8 1.7e-09 37.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAJ16052.1 - 3.7e-13 49.4 0.0 4.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAJ16052.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ16052.1 - 3.3e-06 27.2 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAJ16052.1 - 0.0067 15.8 0.5 0.017 14.4 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Peptidase_S10 PF00450.22 OAJ16053.1 - 1.6e-98 330.9 0.0 2.1e-98 330.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 OAJ16054.1 - 7e-27 94.4 5.4 9e-22 77.5 0.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ16054.1 - 5.9e-25 87.9 30.4 4.6e-17 62.0 13.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 OAJ16055.1 - 2.6e-24 86.0 0.3 6.6e-14 51.8 0.0 4.2 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ16055.1 - 5.1e-14 52.6 1.1 2.5e-08 34.4 1.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.19 OAJ16055.1 - 0.057 13.3 0.0 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Thi4 PF01946.17 OAJ16055.1 - 0.066 12.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 OAJ16055.1 - 0.066 12.5 0.0 0.94 8.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 OAJ16081.1 - 1.1e-18 67.7 0.2 4.1e-18 65.9 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ16081.1 - 2.3e-17 63.2 0.0 1.8e-10 41.0 0.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 OAJ16081.1 - 4.3e-16 58.7 0.1 1.2e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Antibiotic_NAT PF02522.14 OAJ16081.1 - 0.0021 17.9 0.6 0.0048 16.7 0.6 1.5 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase FSA_C PF10479.9 OAJ16081.1 - 0.5 8.4 8.4 1.3 7.1 8.4 1.6 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BolA PF01722.18 OAJ16082.1 - 3.2e-29 101.0 0.3 4.2e-29 100.6 0.3 1.2 1 0 0 1 1 1 1 BolA-like protein CNH PF00780.22 OAJ16083.1 - 1.2e-80 271.1 0.0 2.1e-80 270.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 OAJ16083.1 - 4.4e-44 149.8 0.0 9e-44 148.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAJ16083.1 - 2.7e-37 128.8 0.6 4.2e-37 128.1 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAJ16083.1 - 6.2e-13 48.6 0.0 1.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 OAJ16083.1 - 0.0018 18.1 0.2 0.0087 15.9 0.1 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 OAJ16083.1 - 0.2 11.5 0.4 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF3577 PF12101.8 OAJ16084.1 - 8e-75 249.0 0.0 7.4e-44 148.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3577) Ribosomal_L26 PF16906.5 OAJ16085.1 - 0.14 12.6 0.1 65 4.1 0.0 3.4 3 0 0 3 3 3 0 Ribosomal proteins L26 eukaryotic, L24P archaeal HEAT PF02985.22 OAJ16105.1 - 3.9e-24 82.7 20.1 0.085 13.2 0.0 17.3 17 0 0 17 17 17 5 HEAT repeat HEAT_2 PF13646.6 OAJ16105.1 - 2.2e-19 69.7 36.9 0.00023 21.5 0.0 13.0 9 3 3 12 12 12 5 HEAT repeats HEAT_EZ PF13513.6 OAJ16105.1 - 5.1e-14 52.4 38.0 0.00023 21.6 0.0 14.9 16 2 2 18 18 16 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ16105.1 - 7.8e-09 36.0 0.0 0.021 15.4 0.0 5.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAJ16105.1 - 2.8e-07 30.3 0.0 0.00028 20.6 0.0 4.0 2 1 1 3 3 3 1 CLASP N terminal IFRD PF05004.13 OAJ16105.1 - 4.9e-05 22.6 5.6 2.5 7.1 0.0 6.2 7 0 0 7 7 7 1 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 OAJ16105.1 - 5.6e-05 23.3 4.0 0.1 12.9 0.0 5.5 6 0 0 6 6 5 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 OAJ16105.1 - 0.00088 18.5 0.2 6.7 5.8 0.0 3.5 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.7 OAJ16105.1 - 0.0011 17.8 0.5 1.7 7.2 0.0 3.2 2 1 1 3 3 3 2 Proteasome stabiliser RTP1_C1 PF10363.9 OAJ16105.1 - 0.0045 17.1 3.2 8.1 6.7 0.0 5.2 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 DRIM PF07539.12 OAJ16105.1 - 0.0049 15.2 6.3 0.028 12.7 0.0 4.2 3 1 0 4 4 4 1 Down-regulated in metastasis DUF3437 PF11919.8 OAJ16105.1 - 0.18 11.7 0.0 9.7 6.2 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Arm PF00514.23 OAJ16105.1 - 0.86 9.7 3.8 1.1e+02 3.0 0.0 5.0 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat VID27 PF08553.10 OAJ16106.1 - 3.1e-151 503.5 0.0 4.6e-151 502.9 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAJ16106.1 - 3.9e-38 131.0 0.0 3.9e-38 131.0 0.0 3.7 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 OAJ16106.1 - 2.5e-26 92.1 3.3 7.2e-26 90.6 3.3 1.9 1 0 0 1 1 1 1 VID27 PH-like domain YL1 PF05764.13 OAJ16106.1 - 0.45 10.6 35.3 0.066 13.3 22.5 2.4 2 0 0 2 2 2 0 YL1 nuclear protein FAM176 PF14851.6 OAJ16106.1 - 3.7 7.2 18.0 3.8 7.2 2.0 3.7 3 0 0 3 3 3 0 FAM176 family VID27_PH PF17747.1 OAJ16107.1 - 2.1e-25 89.1 5.2 4.8e-25 88.0 5.2 1.6 1 1 0 1 1 1 1 VID27 PH-like domain VID27_N PF17748.1 OAJ16107.1 - 0.019 14.8 0.2 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 VID27 N-terminal region PAS_9 PF13426.7 OAJ16109.1 - 3.9e-24 84.9 0.0 7.1e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 OAJ16109.1 - 5.6e-16 58.5 0.0 4e-09 36.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 OAJ16109.1 - 1.8e-13 50.6 0.0 7.7e-08 32.5 0.0 4.0 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 OAJ16109.1 - 1.2e-08 35.2 0.0 0.0016 18.6 0.0 4.8 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 OAJ16109.1 - 1.6e-05 24.8 0.0 0.0084 16.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 OAJ16109.1 - 0.0084 16.2 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain SH2_2 PF14633.6 OAJ16133.1 - 3e-75 252.3 0.1 3e-75 252.3 0.1 2.0 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 OAJ16133.1 - 3.3e-23 82.0 0.0 6.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OAJ16133.1 - 1.1e-19 70.7 1.3 5.4e-13 49.0 0.0 2.9 3 0 0 3 3 3 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 OAJ16133.1 - 2e-16 60.3 26.0 2e-16 60.3 26.0 7.2 7 1 1 8 8 8 2 Acidic N-terminal SPT6 HTH_44 PF14641.6 OAJ16133.1 - 4.4e-09 36.8 0.1 4.4e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 OAJ16133.1 - 0.00064 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain ADPRTs_Tse2 PF18648.1 OAJ16133.1 - 0.0053 16.8 2.0 0.021 14.9 2.0 2.0 1 0 0 1 1 1 1 Tse2 ADP-ribosyltransferase toxins HHH_3 PF12836.7 OAJ16133.1 - 0.03 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif CTD PF12815.7 OAJ16133.1 - 0.063 13.9 8.9 2.8 8.6 3.5 2.4 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HHH_9 PF17674.1 OAJ16133.1 - 3.2 8.7 6.7 0.32 11.9 0.1 3.0 3 1 0 3 3 3 0 HHH domain dCMP_cyt_deam_1 PF00383.23 OAJ16135.1 - 2.7e-20 72.1 0.0 4.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ16135.1 - 2e-18 66.4 0.1 2.5e-17 62.9 0.1 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAJ16135.1 - 2.3e-05 24.5 0.0 3.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase Cyt-b5 PF00173.28 OAJ16136.1 - 3.1e-25 88.1 0.0 4.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MULE PF10551.9 OAJ16137.1 - 6.4e-21 74.6 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ16137.1 - 2e-06 26.9 0.0 3.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.15 OAJ16137.1 - 5.2e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase zf-C2H2_10 PF16588.5 OAJ16137.1 - 0.037 13.8 2.1 0.082 12.7 2.1 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger EB PF01683.18 OAJ16138.1 - 1.4 9.3 96.9 0.49 10.7 6.2 9.3 2 2 6 8 8 8 0 EB module Glyco_transf_22 PF03901.17 OAJ16139.1 - 1.4e-82 278.2 12.7 4.8e-64 217.1 6.8 2.8 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 OAJ16139.1 - 5.6e-06 26.7 2.1 5.6e-06 26.7 2.1 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 OAJ16140.1 - 1.4e-10 41.5 0.3 9.8e-05 23.1 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16140.1 - 4.9e-05 23.5 0.0 0.14 12.5 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3123 PF11321.8 OAJ16140.1 - 0.057 14.1 0.4 0.15 12.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Y_phosphatase2 PF03162.13 OAJ16141.1 - 1.4e-56 190.6 0.0 2.2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAJ16141.1 - 1.4e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ16141.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ16141.1 - 0.0097 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4050 PF13259.6 OAJ16141.1 - 1.3 9.4 9.4 1.1 9.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) RNA_pol_3_Rpc31 PF11705.8 OAJ16141.1 - 2.3 8.4 12.9 5.2 7.3 12.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cellulase PF00150.18 OAJ16142.1 - 8.7e-16 58.2 0.4 1.3e-15 57.6 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) fn3_2 PF16893.5 OAJ16143.1 - 2.1e-37 127.1 0.1 3.4e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 OAJ16143.1 - 1.1e-25 89.3 0.1 2.2e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 OAJ16143.1 - 4.6e-08 33.3 0.0 8.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ16143.1 - 5.7e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 OAJ16143.1 - 5.9e-05 23.2 0.0 5.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 OAJ16143.1 - 0.0019 18.6 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 OAJ16143.1 - 0.0024 18.2 0.3 0.0097 16.2 0.3 2.0 1 1 0 1 1 1 1 Fibronectin type III domain Myc_N PF01056.18 OAJ16143.1 - 0.27 11.1 8.9 0.5 10.2 8.9 1.5 1 1 0 1 1 1 0 Myc amino-terminal region ADH_zinc_N PF00107.26 OAJ16164.1 - 5.2e-12 45.9 0.1 1.1e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ16164.1 - 7.9e-09 35.4 1.2 1.3e-07 31.4 1.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAJ16164.1 - 1e-07 33.1 0.0 2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HsbA PF12296.8 OAJ16165.1 - 1.7e-07 31.6 4.6 2.8e-07 31.0 4.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A GAT PF03127.14 OAJ16165.1 - 0.003 17.9 0.4 0.07 13.4 0.1 2.3 2 0 0 2 2 2 1 GAT domain SNF2_N PF00176.23 OAJ16166.1 - 3.8e-68 229.8 0.2 8.2e-68 228.7 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ16166.1 - 3.2e-21 75.8 1.2 1.5e-19 70.3 0.0 3.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 OAJ16166.1 - 2e-20 72.9 11.1 2e-20 72.9 11.1 2.5 2 0 0 2 2 2 1 HSA Bromodomain PF00439.25 OAJ16166.1 - 1.9e-15 56.7 0.2 4.6e-15 55.5 0.2 1.6 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 OAJ16166.1 - 9.1e-13 48.6 1.3 9.1e-13 48.6 1.3 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 OAJ16166.1 - 8e-11 41.5 4.0 1.9e-10 40.3 4.0 1.7 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 OAJ16166.1 - 3.7e-10 40.1 0.1 1.5e-08 34.9 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Cpn60_TCP1 PF00118.24 OAJ16167.1 - 2.3e-149 498.2 13.1 2.7e-149 497.9 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 OAJ16167.1 - 0.0002 20.9 0.2 0.00084 18.9 0.1 2.1 2 0 0 2 2 2 1 Telomere recombination Abhydrolase_3 PF07859.13 OAJ16168.1 - 1.4e-06 28.3 1.1 2e-06 27.8 0.3 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OAJ16168.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase COesterase PF00135.28 OAJ16168.1 - 0.23 10.3 0.0 0.84 8.4 0.0 1.8 1 1 0 1 1 1 0 Carboxylesterase family 4HBT_2 PF13279.6 OAJ16170.1 - 0.00046 20.7 0.0 0.00078 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily EI24 PF07264.11 OAJ16171.1 - 3.3e-22 79.6 15.0 4.9e-22 79.0 15.0 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SelP_N PF04592.14 OAJ16173.1 - 1.9 7.8 8.4 2.5 7.4 8.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Bromodomain PF00439.25 OAJ16193.1 - 2.4e-18 66.0 0.0 4.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BC10 PF06726.12 OAJ16194.1 - 1.2e-11 44.6 9.2 2.1e-11 43.8 9.2 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF4698 PF15769.5 OAJ16194.1 - 0.016 14.3 1.9 0.028 13.5 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) FlxA PF14282.6 OAJ16194.1 - 0.031 14.3 10.0 0.068 13.2 10.0 1.5 1 0 0 1 1 1 0 FlxA-like protein SKA1 PF07160.12 OAJ16194.1 - 1 9.1 5.4 2 8.2 5.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DASH_Spc19 PF08287.11 OAJ16194.1 - 4.1 7.3 10.3 7.9 6.3 10.3 1.4 1 0 0 1 1 1 0 Spc19 SWIB PF02201.18 OAJ16195.1 - 4.5e-29 100.1 0.0 7.1e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAJ16195.1 - 5.3e-08 32.7 2.2 3.4e-06 26.9 0.7 3.2 3 0 0 3 3 3 1 DEK C terminal domain TFIIF_alpha PF05793.12 OAJ16195.1 - 4.6 5.7 11.3 0.31 9.6 4.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LSM PF01423.22 OAJ16196.1 - 8.4e-17 60.6 0.1 1e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF5497 PF17601.2 OAJ16196.1 - 0.034 14.4 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5497) Mcl1_mid PF12341.8 OAJ16197.1 - 1.7e-72 244.3 0.0 2.8e-71 240.3 0.0 2.3 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OAJ16197.1 - 2.7e-12 47.0 4.2 0.0025 18.6 0.0 5.7 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16197.1 - 8.8e-06 25.9 0.0 0.1 12.9 0.0 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAJ16197.1 - 0.19 11.7 0.0 0.64 10.1 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Piwi PF02171.17 OAJ16198.1 - 3.8e-78 262.8 0.0 5.5e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAJ16198.1 - 1.6e-15 58.0 0.0 3.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAJ16198.1 - 1e-14 53.9 0.0 2.8e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAJ16198.1 - 1.8e-12 47.4 0.1 4.9e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAJ16198.1 - 3.2e-12 46.5 0.0 7.8e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 OAJ16198.1 - 1.3e-10 41.2 0.0 2.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Alpha-amyl_C2 PF07821.12 OAJ16198.1 - 0.14 12.4 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Alpha-amylase C-terminal beta-sheet domain Ferrochelatase PF00762.19 OAJ16199.1 - 4.7e-107 357.7 0.0 5.7e-107 357.5 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 OAJ16199.1 - 0.0015 18.8 0.0 0.32 11.4 0.0 2.4 2 0 0 2 2 2 2 CbiX Malic_M PF03949.15 OAJ16200.1 - 1.2e-91 306.5 0.0 1.7e-91 306.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAJ16200.1 - 2e-63 213.5 0.0 3.6e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain UMP1 PF05348.11 OAJ16218.1 - 5.9e-29 100.7 1.2 7.5e-29 100.4 1.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 BIR PF00653.21 OAJ16219.1 - 7.2e-29 100.3 3.0 6.5e-21 74.8 1.9 3.0 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain Tfb4 PF03850.14 OAJ16219.1 - 0.22 11.0 4.7 0.5 9.8 4.7 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 Lin-8 PF03353.15 OAJ16219.1 - 0.71 9.4 17.6 2.1 7.9 17.6 1.8 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PI3K_1B_p101 PF10486.9 OAJ16219.1 - 5.8 4.6 12.2 9.9 3.8 12.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Seryl_tRNA_N PF02403.22 OAJ16220.1 - 0.082 13.1 0.7 0.23 11.7 0.7 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 OAJ16220.1 - 1.5 8.9 6.5 0.8 9.8 2.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pectate_lyase_3 PF12708.7 OAJ16221.1 - 4.8e-79 265.2 4.2 5.6e-62 209.4 1.7 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAJ16221.1 - 2.2e-05 24.0 2.0 0.048 13.4 0.0 3.3 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase CAP_N PF01213.19 OAJ16224.1 - 5.6 6.3 9.6 0.17 11.3 1.0 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF572 PF04502.13 OAJ16225.1 - 2.1e-64 218.3 3.0 2.4e-64 218.1 3.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3052 PF11253.8 OAJ16225.1 - 0.026 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) DUF866 PF05907.13 OAJ16225.1 - 0.041 13.8 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Zn-ribbon_8 PF09723.10 OAJ16225.1 - 0.34 11.1 2.1 0.47 10.6 0.5 2.1 2 0 0 2 2 2 0 Zinc ribbon domain EphA2_TM PF14575.6 OAJ16226.1 - 0.015 16.2 0.1 0.075 13.9 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OAJ16226.1 - 0.062 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 TNFR_16_TM PF18422.1 OAJ16226.1 - 1.2 9.1 3.7 1.7 8.6 1.2 2.2 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4097 PF13349.6 OAJ16252.1 - 0.00028 20.3 0.2 0.0046 16.3 0.1 2.5 2 1 0 2 2 2 1 Putative adhesin PBP1_TM PF14812.6 OAJ16252.1 - 2.1 8.8 15.7 7.7 7.0 0.9 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tri3 PF07428.11 OAJ16253.1 - 2.2e-06 26.8 0.0 1.4e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 TP_methylase PF00590.20 OAJ16254.1 - 2.9e-34 118.9 0.2 5.3e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 OAJ16254.1 - 3.3e-11 42.4 0.4 6.7e-11 41.4 0.4 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 OAJ16254.1 - 4.5e-08 33.5 0.0 0.00017 21.9 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAJ16254.1 - 9.8e-08 31.5 0.0 7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Herpes_pp85 PF04637.12 OAJ16254.1 - 0.29 9.5 0.2 0.55 8.6 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tetraspanin PF00335.20 OAJ16255.1 - 0.00065 19.5 10.7 0.00065 19.5 10.7 1.7 1 1 1 2 2 2 1 Tetraspanin family TMEM51 PF15345.6 OAJ16255.1 - 0.021 14.7 0.4 0.5 10.2 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 COX4_pro_2 PF07835.12 OAJ16255.1 - 0.052 13.7 0.4 0.052 13.7 0.4 3.0 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV MIG-14_Wnt-bd PF06664.12 OAJ16255.1 - 0.1 11.8 8.0 0.075 12.2 6.4 1.5 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion EphA2_TM PF14575.6 OAJ16255.1 - 1.3 10.0 0.0 1.3 10.0 0.0 3.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF3446 PF11928.8 OAJ16256.1 - 0.53 10.6 5.6 1.4 9.3 5.6 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain MscS_TM PF12794.7 OAJ16256.1 - 1.4 7.7 3.5 2.2 7.1 3.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Tropomyosin_1 PF12718.7 OAJ16257.1 - 3.3e-47 160.2 29.7 4e-47 160.0 29.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAJ16257.1 - 2.1e-11 43.7 30.6 3e-06 26.8 11.0 2.4 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 OAJ16257.1 - 0.00027 21.0 31.0 0.0017 18.4 8.5 3.3 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 OAJ16257.1 - 0.00089 19.7 2.9 0.00089 19.7 2.9 3.7 2 2 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase HrpB7 PF09486.10 OAJ16257.1 - 0.0014 19.0 20.1 0.011 16.1 6.3 2.3 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 OAJ16257.1 - 0.0021 18.1 12.7 0.0021 18.1 12.7 2.5 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 OAJ16257.1 - 0.0029 17.7 30.0 0.019 15.0 12.9 2.6 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 OAJ16257.1 - 0.0031 16.5 29.1 0.12 11.3 10.7 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Uso1_p115_C PF04871.13 OAJ16257.1 - 0.0035 17.7 32.1 0.005 17.2 13.5 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region RasGAP_C PF03836.15 OAJ16257.1 - 0.0041 17.3 5.3 0.0041 17.3 5.3 2.0 1 1 1 2 2 2 1 RasGAP C-terminus Fez1 PF06818.15 OAJ16257.1 - 0.0053 17.2 23.0 0.0053 17.2 23.0 1.5 1 1 0 1 1 1 1 Fez1 GAS PF13851.6 OAJ16257.1 - 0.0075 15.6 25.6 0.068 12.5 7.2 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ERM PF00769.19 OAJ16257.1 - 0.0086 15.9 33.6 0.44 10.3 15.8 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family FliD_C PF07195.12 OAJ16257.1 - 0.0097 15.4 11.7 0.02 14.3 3.9 2.5 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus ADIP PF11559.8 OAJ16257.1 - 0.012 15.7 26.8 0.61 10.2 7.0 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 OAJ16257.1 - 0.016 14.6 23.1 0.17 11.2 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 OAJ16257.1 - 0.02 14.9 33.8 0.25 11.4 7.8 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4763 PF15960.5 OAJ16257.1 - 0.021 14.2 12.5 0.16 11.2 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) GIT_CC PF16559.5 OAJ16257.1 - 0.039 13.8 1.6 0.039 13.8 1.6 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 OAJ16257.1 - 0.039 14.0 14.2 0.071 13.1 2.3 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) CASP_C PF08172.12 OAJ16257.1 - 0.04 13.3 20.5 0.31 10.3 14.9 2.0 1 1 1 2 2 2 0 CASP C terminal Csm1_N PF18504.1 OAJ16257.1 - 0.041 14.2 5.3 0.041 14.2 5.3 3.5 2 2 2 4 4 4 0 Csm1 N-terminal domain DUF4200 PF13863.6 OAJ16257.1 - 0.047 14.1 28.6 0.27 11.7 8.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 OAJ16257.1 - 0.065 12.7 25.4 0.085 12.3 25.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal XhlA PF10779.9 OAJ16257.1 - 0.086 13.1 22.5 0.21 11.8 5.3 3.9 1 1 2 3 3 3 0 Haemolysin XhlA EzrA PF06160.12 OAJ16257.1 - 0.093 10.9 22.3 0.017 13.3 9.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 OAJ16257.1 - 0.11 13.0 35.2 2.2 8.8 13.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 OAJ16257.1 - 0.12 12.7 16.0 1.1 9.6 2.1 3.0 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 OAJ16257.1 - 0.16 11.7 25.9 0.75 9.6 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Filament PF00038.21 OAJ16257.1 - 0.17 11.5 25.9 0.43 10.1 11.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF919 PF06034.11 OAJ16257.1 - 0.2 11.5 7.4 0.16 11.8 0.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF5082 PF16888.5 OAJ16257.1 - 0.21 11.9 17.6 1.3 9.3 4.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) T3SSipB PF16535.5 OAJ16257.1 - 0.29 11.6 17.9 2.5 8.5 17.5 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB Lebercilin PF15619.6 OAJ16257.1 - 0.37 10.4 30.0 1.6 8.4 13.4 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 OAJ16257.1 - 0.39 8.2 24.7 0.45 8.0 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 OAJ16257.1 - 0.39 10.9 14.3 0.72 10.0 4.1 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4927 PF16279.5 OAJ16257.1 - 0.41 11.7 12.5 0.067 14.2 3.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4927) Jnk-SapK_ap_N PF09744.9 OAJ16257.1 - 0.42 10.8 31.7 0.48 10.6 10.1 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Dynamitin PF04912.14 OAJ16257.1 - 0.46 9.7 22.7 0.13 11.6 17.4 2.3 1 1 1 2 2 2 0 Dynamitin Prefoldin_2 PF01920.20 OAJ16257.1 - 0.53 10.3 26.1 2.6 8.0 4.8 3.7 1 1 1 3 3 3 0 Prefoldin subunit DUF2730 PF10805.8 OAJ16257.1 - 0.54 10.4 10.2 0.23 11.6 2.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) KLRAQ PF10205.9 OAJ16257.1 - 0.69 10.2 18.5 0.43 10.9 6.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 OAJ16257.1 - 0.7 8.9 22.6 0.27 10.3 14.3 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 OAJ16257.1 - 0.84 9.8 29.7 2.6 8.2 11.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OAJ16257.1 - 0.84 10.3 15.3 0.28 11.8 3.1 3.3 1 1 3 4 4 4 0 SlyX Golgin_A5 PF09787.9 OAJ16257.1 - 1.1 8.7 26.1 5.1 6.5 26.1 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 IFT57 PF10498.9 OAJ16257.1 - 1.2 8.0 19.2 0.69 8.8 3.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.8 OAJ16257.1 - 1.3 9.1 33.8 0.45 10.5 11.7 3.7 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 OAJ16257.1 - 1.5 9.2 22.4 0.045 14.1 5.4 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CLZ PF16526.5 OAJ16257.1 - 1.5 9.2 23.5 1.8 9.0 2.5 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF812 PF05667.11 OAJ16257.1 - 1.6 7.5 26.1 3.4 6.5 26.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 OAJ16257.1 - 1.7 7.9 20.3 2.7 7.3 20.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 OAJ16257.1 - 1.9 8.5 5.5 0.65 10.0 1.9 2.1 2 0 0 2 2 2 0 Sec20 Sec34 PF04136.15 OAJ16257.1 - 1.9 8.3 13.5 0.29 11.0 2.7 2.3 1 1 1 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 OAJ16257.1 - 2.1 6.2 15.9 1.9 6.3 14.9 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF5320 PF17253.2 OAJ16257.1 - 2.1 9.4 16.4 1.1 10.4 1.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5320) TRAF_BIRC3_bd PF16673.5 OAJ16257.1 - 2.2 8.2 15.6 0.51 10.2 4.4 3.3 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF2203 PF09969.9 OAJ16257.1 - 2.2 9.0 18.6 1 10.1 4.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CorA PF01544.18 OAJ16257.1 - 2.4 7.4 6.6 3.5 6.8 6.5 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.12 OAJ16257.1 - 2.5 8.1 16.3 2.7 8.0 5.0 2.6 1 1 0 2 2 2 0 Laminin Domain II YscO PF07321.12 OAJ16257.1 - 2.7 8.0 31.2 3.1 7.7 12.6 2.7 1 1 1 2 2 2 0 Type III secretion protein YscO Allexi_40kDa PF05549.11 OAJ16257.1 - 3.3 7.2 13.0 4.1 6.8 6.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF16 PF01519.16 OAJ16257.1 - 3.3 8.3 15.0 1.2 9.7 2.9 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 DUF730 PF05325.11 OAJ16257.1 - 3.3 7.8 11.6 2.3 8.2 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF730) KASH_CCD PF14662.6 OAJ16257.1 - 3.4 7.5 27.3 0.71 9.7 9.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tup_N PF08581.10 OAJ16257.1 - 3.5 8.0 18.1 0.69 10.3 3.4 2.4 2 1 0 2 2 2 0 Tup N-terminal DUF4472 PF14739.6 OAJ16257.1 - 5 7.9 24.0 10 6.9 9.5 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) LPP PF04728.13 OAJ16257.1 - 5.3 7.5 9.7 1.6 9.2 0.1 3.7 2 2 1 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 OAJ16257.1 - 6 7.3 18.5 5.6 7.4 1.5 4.4 1 1 5 6 6 6 0 Flagella accessory protein C (FlaC) GTP-bdg_M PF16360.5 OAJ16257.1 - 6.1 7.5 14.8 0.19 12.3 2.3 3.3 2 2 1 3 3 3 0 GTP-binding GTPase Middle Region KxDL PF10241.9 OAJ16257.1 - 6.8 7.0 15.9 0.49 10.7 2.8 3.4 1 1 3 4 4 4 0 Uncharacterized conserved protein HemX PF04375.14 OAJ16257.1 - 6.9 5.9 19.4 2 7.6 6.7 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Prominin PF05478.11 OAJ16257.1 - 7.8 4.3 8.7 8.8 4.1 8.7 1.1 1 0 0 1 1 1 0 Prominin HAUS-augmin3 PF14932.6 OAJ16257.1 - 8 6.0 26.1 1.1 8.7 13.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Aminotran_5 PF00266.19 OAJ16258.1 - 1.3e-29 103.3 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 OAJ16258.1 - 0.0033 17.4 0.0 0.0096 15.9 0.0 1.8 1 1 0 1 1 1 1 B12 binding domain DUF4097 PF13349.6 OAJ16259.1 - 6.9e-05 22.3 0.8 0.00016 21.1 0.8 1.6 1 1 0 1 1 1 1 Putative adhesin PBP_N PF17093.5 OAJ16259.1 - 0.012 15.9 0.6 0.012 15.9 0.6 2.1 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus TPR_1 PF00515.28 OAJ16285.1 - 3e-29 99.6 28.9 4.2e-05 23.2 0.3 13.9 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ16285.1 - 1.2e-24 84.4 70.5 0.00012 21.9 1.4 19.0 20 0 0 20 20 19 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ16285.1 - 2.8e-24 83.3 16.3 0.017 15.3 0.0 14.9 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ16285.1 - 3.5e-20 71.0 94.6 0.00013 22.5 0.4 18.9 14 3 5 19 19 18 7 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ16285.1 - 3.8e-18 64.9 24.5 0.00016 21.3 0.3 10.8 12 1 1 13 13 13 4 TPR repeat TPR_17 PF13431.6 OAJ16285.1 - 1.3e-16 59.7 23.6 0.022 15.1 0.1 12.9 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ16285.1 - 4.9e-13 49.5 120.8 0.00016 22.3 2.1 18.2 15 4 0 17 17 17 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ16285.1 - 2.2e-10 40.7 74.1 2.2e-09 37.5 2.5 13.4 14 2 2 16 16 16 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ16285.1 - 5.5e-10 39.6 72.6 0.00087 19.8 1.5 12.9 11 3 2 14 14 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ16285.1 - 1.2e-08 35.0 42.0 0.0078 16.8 0.0 13.8 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ16285.1 - 3.8e-08 32.8 29.6 0.38 10.9 0.1 10.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ16285.1 - 7.6e-08 32.0 16.4 0.073 13.0 0.1 8.1 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ16285.1 - 0.0035 17.4 9.3 0.68 10.0 0.8 5.7 5 0 0 5 5 4 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 OAJ16285.1 - 0.0036 17.4 60.1 0.46 10.7 1.4 12.6 12 2 2 14 14 12 3 Tetratricopeptide repeat SNAP PF14938.6 OAJ16285.1 - 0.0044 16.5 4.5 0.0044 16.5 4.5 5.1 5 0 0 5 5 5 1 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 OAJ16285.1 - 0.017 15.8 1.1 14 6.6 0.0 4.8 3 0 0 3 3 3 0 Sel1 repeat TPR_22 PF18833.1 OAJ16285.1 - 0.038 14.1 0.1 0.16 12.1 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ16285.1 - 0.086 13.1 31.4 0.027 14.7 0.9 8.0 9 1 2 11 11 10 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 OAJ16285.1 - 0.14 11.2 2.7 6.1 5.7 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 OAJ16285.1 - 0.18 11.0 8.8 1.5 8.0 0.9 4.5 3 1 2 5 5 5 0 FAT domain TPR_20 PF14561.6 OAJ16285.1 - 0.46 10.9 35.5 1.7 9.1 0.2 8.0 5 3 1 7 7 6 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 OAJ16286.1 - 3.9e-12 46.2 0.1 6e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 OAJ16287.1 - 4.3e-45 153.3 0.4 1.4e-44 151.6 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 OAJ16287.1 - 3.3e-12 46.4 28.5 1e-07 32.1 7.2 3.3 3 0 0 3 3 3 2 LIM domain SUIM_assoc PF16619.5 OAJ16287.1 - 2.3e-09 37.2 0.0 0.00021 21.3 0.0 4.5 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 C1_1 PF00130.22 OAJ16287.1 - 9.9e-06 25.4 7.2 9.9e-06 25.4 7.2 3.5 2 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Serglycin PF04360.12 OAJ16287.1 - 0.033 14.1 0.2 0.033 14.1 0.2 5.1 5 0 0 5 5 5 0 Serglycin Suppressor_APC PF11414.8 OAJ16287.1 - 0.14 12.2 2.7 0.94 9.6 2.7 2.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein GP67 PF17634.2 OAJ16287.1 - 0.6 10.6 9.1 3.2 8.2 0.4 2.5 2 0 0 2 2 2 0 Gene product 67 KH_1 PF00013.29 OAJ16288.1 - 1.8e-31 107.7 0.6 1.4e-08 34.4 0.0 6.2 7 0 0 7 7 7 4 KH domain UQ_con PF00179.26 OAJ16289.1 - 1.4e-11 44.2 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF202 PF02656.15 OAJ16290.1 - 7.5e-14 51.9 5.3 7.5e-14 51.9 5.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX2_TM PF02790.15 OAJ16290.1 - 0.0037 17.4 0.7 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, transmembrane domain DUF5337 PF17272.2 OAJ16290.1 - 1.3 8.9 6.6 1.9 8.4 5.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF2615 PF11027.8 OAJ16290.1 - 3.1 8.0 3.9 1.7 8.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DnaJ PF00226.31 OAJ16291.1 - 1.1e-19 70.3 0.2 1.9e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1682 PF07946.14 OAJ16291.1 - 0.58 9.3 10.7 0.76 8.9 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ENTH PF01417.20 OAJ16315.1 - 4.1e-47 159.3 0.0 9.4e-47 158.1 0.0 1.6 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 OAJ16315.1 - 0.00064 19.5 5.2 0.47 10.5 0.8 3.2 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 OAJ16315.1 - 0.49 9.3 11.3 0.011 14.7 3.1 2.3 2 1 0 2 2 2 0 ANTH domain GAGA_bind PF06217.12 OAJ16315.1 - 7.1 6.8 17.4 1.9 8.7 3.2 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Porin_3 PF01459.22 OAJ16316.1 - 6.6e-61 206.1 0.2 7.9e-61 205.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2911 PF11138.8 OAJ16316.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) ribosomal_L24 PF17136.4 OAJ16317.1 - 0.023 15.1 0.1 0.11 12.9 0.0 2.2 2 1 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 PHD PF00628.29 OAJ16318.1 - 0.062 13.2 14.5 0.036 14.0 10.6 2.7 2 1 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 OAJ16318.1 - 0.1 12.8 1.3 0.25 11.6 1.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain rve PF00665.26 OAJ16319.1 - 9.7e-06 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 OAJ16319.1 - 0.077 12.8 0.3 0.64 9.9 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Cyanate_lyase PF02560.14 OAJ16320.1 - 6.5e-35 118.8 0.0 1.1e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 OAJ16320.1 - 2.2e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 OAJ16320.1 - 0.017 15.1 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.7 OAJ16320.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain RSN1_7TM PF02714.15 OAJ16321.1 - 1.4e-72 244.4 22.8 2.5e-72 243.5 22.8 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ16321.1 - 1.7e-39 135.9 0.3 2.6e-39 135.3 0.3 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ16321.1 - 4e-36 124.1 1.8 1.2e-35 122.6 1.8 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAJ16321.1 - 2.9e-10 40.2 0.0 8.5e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Dicistro_VP4 PF11492.8 OAJ16321.1 - 0.022 14.7 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 LSM PF01423.22 OAJ16322.1 - 5.8e-20 70.8 0.1 6.5e-20 70.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ16322.1 - 4.3e-06 26.8 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAJ16322.1 - 0.00058 19.9 0.1 0.00068 19.7 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Velvet PF11754.8 OAJ16323.1 - 1.9e-43 149.2 0.0 1.6e-30 106.9 0.1 5.1 3 2 1 4 4 4 2 Velvet factor TFIIA PF03153.13 OAJ16323.1 - 3.8 7.4 65.0 0.62 10.0 20.6 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 OAJ16324.1 - 2e-19 69.5 2.6 6.8e-19 67.8 0.2 2.9 2 1 0 2 2 2 1 DnaJ domain Aminotran_3 PF00202.21 OAJ16348.1 - 1.1e-88 297.6 0.0 1.6e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III LprI PF07007.12 OAJ16348.1 - 0.056 14.1 0.6 0.17 12.6 0.6 1.8 1 0 0 1 1 1 0 Lysozyme inhibitor LprI DUF3802 PF12290.8 OAJ16348.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) MS_channel PF00924.18 OAJ16349.1 - 1.8e-16 60.3 0.6 2.9e-16 59.7 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAJ16349.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 EF hand Fringe PF02434.16 OAJ16350.1 - 7.2e-06 25.6 0.2 1.7e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OAJ16350.1 - 0.08 12.7 0.0 1.6 8.5 0.0 2.2 1 1 0 1 1 1 0 Galactosyltransferase MS_channel PF00924.18 OAJ16351.1 - 3e-24 85.7 0.6 5.5e-24 84.9 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Flu_PB2 PF00604.17 OAJ16351.1 - 0.15 9.9 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 Flavin_Reduct PF01613.18 OAJ16352.1 - 2e-22 79.9 0.0 2.7e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain BCS1_N PF08740.11 OAJ16354.1 - 2.2e-49 168.0 0.2 3.1e-49 167.5 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAJ16354.1 - 7.2e-17 62.0 0.0 2.3e-16 60.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ16354.1 - 0.00025 20.3 0.0 0.00057 19.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OAJ16354.1 - 0.00071 20.0 1.4 0.0083 16.5 0.8 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OAJ16354.1 - 0.0031 17.2 0.1 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAJ16354.1 - 0.0079 15.8 0.1 0.13 11.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 OAJ16354.1 - 0.031 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OAJ16354.1 - 0.039 14.0 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OAJ16354.1 - 0.046 14.2 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 OAJ16354.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ16354.1 - 0.15 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 OAJ16382.1 - 1.4e-38 133.1 6.7 1.8e-38 132.8 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ16382.1 - 2.9e-33 115.3 0.0 6.6e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAJ16382.1 - 0.00059 19.3 0.2 0.25 10.7 0.0 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ16382.1 - 0.0021 17.9 0.0 0.11 12.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ16382.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAJ16382.1 - 0.016 15.6 0.0 0.14 12.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ16382.1 - 0.029 14.8 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 OAJ16382.1 - 0.053 13.2 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 OAJ16382.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ16382.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OAJ16382.1 - 0.075 13.3 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ribonuc_red_sm PF00268.21 OAJ16382.1 - 0.13 11.7 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain Lipoprotein_2 PF00921.17 OAJ16384.1 - 0.16 11.5 2.9 0.24 10.9 2.9 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein HemY_N PF07219.13 OAJ16384.1 - 1.5 9.1 7.9 5.1 7.3 7.9 1.9 1 0 0 1 1 1 0 HemY protein N-terminus Lipoprotein_2 PF00921.17 OAJ16385.1 - 0.0049 16.5 3.5 0.0055 16.3 3.5 1.0 1 0 0 1 1 1 1 Borrelia lipoprotein Urease_gamma PF00547.18 OAJ16385.1 - 0.047 14.0 1.4 0.075 13.4 1.4 1.3 1 0 0 1 1 1 0 Urease, gamma subunit DUF740 PF05340.12 OAJ16385.1 - 0.57 8.9 6.3 0.67 8.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) HemY_N PF07219.13 OAJ16385.1 - 1.3 9.3 11.9 3.2 8.0 11.9 1.7 1 1 1 2 2 2 0 HemY protein N-terminus DUF5401 PF17380.2 OAJ16385.1 - 2 6.4 13.1 2.4 6.1 13.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Folliculin PF11704.8 OAJ16385.1 - 2.2 8.1 4.7 3.1 7.7 4.7 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Fungal_trans PF04082.18 OAJ16386.1 - 1.6e-18 66.7 0.0 4.1e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ16386.1 - 3.9e-09 36.5 10.9 6.5e-09 35.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spindle_Spc25 PF08234.12 OAJ16387.1 - 1.6e-15 57.1 0.0 4.1e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Creb_binding PF09030.10 OAJ16387.1 - 0.011 16.5 2.4 0.011 16.5 2.4 3.3 3 1 0 3 3 3 0 Creb binding Macoilin PF09726.9 OAJ16387.1 - 0.049 12.2 4.0 0.057 12.0 4.0 1.1 1 0 0 1 1 1 0 Macoilin family CENP-F_leu_zip PF10473.9 OAJ16387.1 - 0.12 12.4 11.2 0.22 11.5 11.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 OAJ16387.1 - 0.31 8.9 0.8 0.37 8.6 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4936 PF16290.5 OAJ16387.1 - 0.39 11.4 4.4 0.89 10.3 2.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4936) DUF4407 PF14362.6 OAJ16387.1 - 0.48 9.7 10.2 0.72 9.1 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OAJ16387.1 - 1.8 7.6 8.5 3.3 6.7 8.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAJ16387.1 - 1.8 7.3 12.4 9.4 5.0 12.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OAJ16387.1 - 9.9 6.4 9.0 2.3 8.4 1.1 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Pkinase PF00069.25 OAJ16388.1 - 1.6e-59 201.4 0.0 1e-58 198.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16388.1 - 9.1e-28 97.2 0.0 1.9e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ16388.1 - 0.00098 18.5 0.1 0.28 10.4 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OAJ16388.1 - 0.0083 16.1 0.5 0.18 11.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ16388.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 OAJ16388.1 - 0.021 15.5 0.1 0.073 13.8 0.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAJ16388.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Myc-LZ PF02344.15 OAJ16388.1 - 0.059 13.5 4.5 4.7 7.4 1.1 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain RIO1 PF01163.22 OAJ16388.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Herpes_TAF50 PF03326.13 OAJ16388.1 - 0.92 8.1 9.0 1.3 7.5 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) GST_C_2 PF13410.6 OAJ16408.1 - 2.5e-16 59.5 0.0 4.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ16408.1 - 6e-15 55.3 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ16408.1 - 3.9e-07 30.2 0.0 7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ16408.1 - 9.7e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ16408.1 - 0.0066 16.8 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Pmp3 PF01679.17 OAJ16410.1 - 2.8e-12 46.6 3.6 5e-12 45.8 3.6 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PMM PF03332.13 OAJ16411.1 - 4.3e-101 337.3 0.4 5.1e-101 337.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OAJ16411.1 - 0.00012 22.0 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.12 OAJ16411.1 - 0.032 14.3 0.4 0.12 12.4 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function, DUF600 Response_reg PF00072.24 OAJ16412.1 - 1.2e-19 70.6 0.0 2.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAJ16412.1 - 8.6e-17 61.7 0.1 2e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAJ16412.1 - 2.4e-07 30.7 0.4 1.1e-06 28.6 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PmbA_TldD PF01523.16 OAJ16412.1 - 0.17 11.7 8.4 0.03 14.2 1.4 2.4 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Sec63 PF02889.16 OAJ16413.1 - 1.5e-30 106.2 0.0 2.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 OAJ16413.1 - 1.1e-08 35.4 0.0 3.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ16413.1 - 9.3e-08 32.0 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ16413.1 - 0.0068 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OAJ16413.1 - 0.028 14.0 0.6 0.096 12.2 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 OAJ16413.1 - 0.042 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCHC PF00098.23 OAJ16438.1 - 1.4e-10 40.8 38.3 4.9e-07 29.5 1.2 5.3 5 0 0 5 5 5 4 Zinc knuckle Zn_Tnp_IS91 PF14319.6 OAJ16438.1 - 5.1 7.2 15.0 3.1 7.9 4.1 2.8 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-CCHC_4 PF14392.6 OAJ16438.1 - 8.6 6.2 19.3 3.8 7.3 0.7 4.4 4 0 0 4 4 4 0 Zinc knuckle 2-Hacid_dh_C PF02826.19 OAJ16439.1 - 7.4e-40 136.2 0.0 1.7e-28 99.2 0.1 2.2 1 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ16439.1 - 7.3e-24 83.9 0.0 9.9e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AAA PF00004.29 OAJ16441.1 - 2.8e-14 53.7 0.0 6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ16441.1 - 1.4e-11 44.4 0.0 4.8e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OAJ16441.1 - 1.1e-09 38.6 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 OAJ16441.1 - 1.4e-05 25.4 0.0 4.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OAJ16441.1 - 8.3e-05 22.6 0.0 0.00026 21.0 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 OAJ16441.1 - 0.00041 20.6 0.2 0.027 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ16441.1 - 0.00046 20.5 0.0 0.0016 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ16441.1 - 0.00073 20.0 0.1 0.012 16.0 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 OAJ16441.1 - 0.00076 19.3 0.0 0.0024 17.7 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ16441.1 - 0.00078 19.2 0.0 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 OAJ16441.1 - 0.00097 19.4 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DUF2075 PF09848.9 OAJ16441.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OAJ16441.1 - 0.002 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ16441.1 - 0.0024 17.6 0.0 0.0068 16.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAJ16441.1 - 0.0029 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ16441.1 - 0.014 14.7 0.0 0.097 12.0 0.0 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAJ16441.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OAJ16441.1 - 0.093 12.7 0.3 1 9.4 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAJ16441.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 OAJ16441.1 - 0.12 12.3 0.0 2 8.4 0.0 2.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit MCM PF00493.23 OAJ16441.1 - 0.15 11.1 0.1 1.2 8.2 0.1 2.2 1 1 0 1 1 1 0 MCM P-loop domain p450 PF00067.22 OAJ16442.1 - 3e-49 168.0 0.0 4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3071 PF11268.8 OAJ16442.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) p450 PF00067.22 OAJ16443.1 - 1.9e-53 181.9 0.0 2.4e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 OAJ16444.1 - 1.2e-46 156.5 6.2 5.5e-16 58.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Smg4_UPF3 PF03467.15 OAJ16445.1 - 1.5e-52 178.1 0.1 1.5e-52 178.1 0.1 3.4 4 0 0 4 4 4 1 Smg-4/UPF3 family LIAS_N PF16881.5 OAJ16445.1 - 0.13 12.6 0.2 0.13 12.6 0.2 2.7 3 0 0 3 3 3 0 N-terminal domain of lipoyl synthase of Radical_SAM family CAP59_mtransfer PF11735.8 OAJ16445.1 - 0.76 9.4 3.3 3.1 7.4 1.9 2.2 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 DUF4773 PF15998.5 OAJ16446.1 - 0.63 10.6 4.5 0.86 10.2 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4773) zf-CCCH PF00642.24 OAJ16473.1 - 9.2e-24 82.8 32.2 7.7e-07 28.9 0.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ16473.1 - 1.5e-20 72.6 34.0 3.6e-06 26.8 3.0 5.6 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAJ16473.1 - 5.2e-11 43.2 24.0 0.00018 22.1 0.4 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAJ16473.1 - 2.8e-06 27.0 0.8 2.8e-06 27.0 0.8 5.2 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCHC PF00098.23 OAJ16473.1 - 3.8e-06 26.7 1.3 3.8e-06 26.7 1.3 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_3 PF15663.5 OAJ16473.1 - 0.00044 20.4 12.9 0.013 15.7 0.1 3.7 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCHC_3 PF13917.6 OAJ16473.1 - 0.016 15.1 3.8 0.044 13.8 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle NPL4 PF05021.15 OAJ16474.1 - 4.7e-91 305.3 0.0 7.3e-89 298.1 0.0 3.1 2 1 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.15 OAJ16474.1 - 4.6e-65 218.2 0.1 7.2e-65 217.6 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAJ16474.1 - 0.00042 20.7 0.0 0.0009 19.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UIM PF02809.20 OAJ16474.1 - 0.0056 16.5 0.6 0.016 15.1 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif SF1-HH PF16275.5 OAJ16475.1 - 0.0037 17.6 0.0 8.4 6.8 0.0 3.0 3 0 0 3 3 3 2 Splicing factor 1 helix-hairpin domain T2SSF PF00482.23 OAJ16475.1 - 0.12 12.4 0.8 20 5.1 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F LtrA PF06772.11 OAJ16475.1 - 0.14 11.4 3.9 2.7 7.1 2.3 2.2 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) Gastrin PF00918.17 OAJ16475.1 - 7.5 7.5 6.6 43 5.1 0.2 3.2 3 0 0 3 3 3 0 Gastrin/cholecystokinin family BUD22 PF09073.10 OAJ16497.1 - 2.3 7.5 9.1 2.7 7.2 9.1 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OAJ16497.1 - 4.7 6.5 8.1 5.6 6.3 8.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ16497.1 - 5.1 5.2 10.2 6 4.9 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCCH_3 PF15663.5 OAJ16498.1 - 0.36 11.1 4.8 6.6 7.0 4.7 2.1 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 OAJ16498.1 - 0.38 10.6 16.1 0.43 10.4 5.9 3.0 2 2 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ16498.1 - 0.6 10.2 11.2 1.2 9.3 0.3 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-C3H1 PF10650.9 OAJ16498.1 - 0.89 9.3 6.6 1.1 9.1 1.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH PF00642.24 OAJ16498.1 - 1.2 9.2 13.0 4.6 7.3 1.0 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAJ16498.1 - 1.9 9.1 11.0 1.6 9.3 3.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PAM2 PF07145.15 OAJ16498.1 - 4.2 7.3 6.2 2.5 8.0 0.2 3.2 3 0 0 3 3 3 0 Ataxin-2 C-terminal region MFS_1 PF07690.16 OAJ16499.1 - 1.7e-33 116.0 36.8 1.5e-27 96.5 0.4 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 OAJ16499.1 - 0.0093 15.7 0.0 0.096 12.5 0.0 2.4 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Tetraspanin PF00335.20 OAJ16500.1 - 0.0019 18.0 0.6 0.0026 17.5 0.6 1.2 1 0 0 1 1 1 1 Tetraspanin family DDE_1 PF03184.19 OAJ16501.1 - 5.3e-21 75.0 0.0 7.5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OAJ16501.1 - 0.007 16.1 0.1 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4681 PF15732.5 OAJ16502.1 - 0.14 12.4 0.3 0.23 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) DDHD PF02862.17 OAJ16503.1 - 4.5 7.4 6.4 6.2 6.9 6.4 1.4 1 0 0 1 1 1 0 DDHD domain zf-C2H2_2 PF12756.7 OAJ16504.1 - 0.0074 16.6 0.0 0.0088 16.4 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Ig_C17orf99 PF17736.1 OAJ16504.1 - 0.045 13.8 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 C17orf99 Ig domain zf-C2H2_jaz PF12171.8 OAJ16504.1 - 2.9 8.3 5.9 0.34 11.2 1.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAJ16505.1 - 0.078 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GPI-anchored PF10342.9 OAJ16531.1 - 8.7e-12 45.6 0.1 1.7e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dak1 PF02733.17 OAJ16532.1 - 1.2e-81 274.1 0.1 1.8e-81 273.5 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAJ16532.1 - 7.9e-38 130.1 4.6 1.8e-37 128.9 4.6 1.6 1 0 0 1 1 1 1 DAK2 domain DOT1 PF08123.13 OAJ16532.1 - 0.21 11.1 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Peptidase_S28 PF05577.12 OAJ16533.1 - 2.7e-38 131.9 0.5 2.4e-33 115.6 0.0 2.9 3 0 0 3 3 3 2 Serine carboxypeptidase S28 Rnk_N PF14760.6 OAJ16533.1 - 0.23 12.0 0.3 0.56 10.7 0.3 1.7 1 0 0 1 1 1 0 Rnk N-terminus CGI-121 PF08617.10 OAJ16534.1 - 8.8e-36 123.5 0.0 1.1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 SKN1 PF03935.15 OAJ16535.1 - 2.5e-176 587.0 0.0 3.3e-176 586.6 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 OAJ16535.1 - 0.035 13.6 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 Iso_dh PF00180.20 OAJ16536.1 - 4.5e-115 384.5 0.0 5.1e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YebG PF07130.12 OAJ16536.1 - 0.069 13.0 0.0 15 5.5 0.0 2.6 2 0 0 2 2 2 0 YebG protein RCC1 PF00415.18 OAJ16537.1 - 2.3e-06 28.1 0.5 12 6.6 0.0 6.2 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ16537.1 - 0.00026 20.7 12.4 0.11 12.3 1.1 5.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAJ16537.1 - 0.0035 17.2 0.2 0.0094 15.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ16537.1 - 0.099 12.5 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain DUF2034 PF10356.9 OAJ16538.1 - 2.2e-14 53.3 4.1 1.6e-13 50.5 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAJ16538.1 - 3.6e-06 27.0 0.0 9.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease MSA_2 PF00985.17 OAJ16538.1 - 0.016 15.6 1.9 0.016 15.6 1.9 1.8 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family Diphtheria_T PF02764.14 OAJ16538.1 - 0.52 10.3 1.5 0.87 9.6 1.5 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain Ndc1_Nup PF09531.10 OAJ16538.1 - 0.85 8.2 5.1 0.95 8.1 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AT_hook PF02178.19 OAJ16538.1 - 1.1 9.4 18.1 0.28 11.2 1.5 4.1 3 0 0 3 3 3 0 AT hook motif Euplotes_phero PF05842.11 OAJ16538.1 - 2.5 8.7 7.6 4.8 7.8 7.6 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein SRP54 PF00448.22 OAJ16539.1 - 1.7e-45 155.1 0.0 2e-28 99.4 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 OAJ16539.1 - 5.9e-45 154.4 0.0 1.1e-44 153.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 OAJ16539.1 - 5.3e-08 33.0 0.0 2.2e-07 31.0 0.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAJ16539.1 - 0.0065 15.5 0.0 0.063 12.2 0.0 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 OAJ16539.1 - 0.008 16.2 0.0 0.039 14.0 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 OAJ16539.1 - 0.045 14.1 2.6 0.31 11.4 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain Fer4_NifH PF00142.18 OAJ16539.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 OAJ16539.1 - 0.089 12.7 0.0 0.44 10.4 0.0 2.0 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.6 OAJ16539.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ16539.1 - 0.15 12.4 0.0 0.64 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 OAJ16539.1 - 0.15 11.2 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase T3SS_needle_reg PF09025.10 OAJ16539.1 - 0.23 11.4 1.5 1.6 8.7 0.1 2.6 3 0 0 3 3 3 0 YopR, type III needle-polymerisation regulator MMR_HSR1 PF01926.23 OAJ16539.1 - 0.33 11.0 1.6 3 8.0 0.5 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Mto2_bdg PF12808.7 OAJ16560.1 - 0.0043 17.3 0.1 0.0073 16.6 0.1 1.3 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region BRE1 PF08647.11 OAJ16560.1 - 0.027 14.5 0.9 0.036 14.1 0.9 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase IFT57 PF10498.9 OAJ16560.1 - 0.039 12.9 0.3 0.049 12.6 0.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.9 OAJ16560.1 - 0.058 13.4 0.3 0.087 12.9 0.3 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DIM PF08194.12 OAJ16561.1 - 0.58 10.4 0.1 0.58 10.4 0.1 3.0 4 0 0 4 4 4 0 DIM protein BRAP2 PF07576.12 OAJ16562.1 - 6.1e-27 93.8 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OAJ16562.1 - 3.6e-17 62.4 4.5 1.1e-16 60.9 4.5 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OAJ16562.1 - 2.5e-08 34.1 10.3 2.5e-08 34.1 10.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAJ16562.1 - 6.8e-06 26.3 6.9 6.8e-06 26.3 6.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAJ16562.1 - 3.5e-05 23.6 9.4 3.5e-05 23.6 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ16562.1 - 3.8e-05 23.6 4.5 0.00014 21.8 4.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ16562.1 - 0.00013 21.7 10.4 0.00013 21.7 10.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ16562.1 - 0.00026 20.7 4.1 0.00026 20.7 4.1 2.4 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAJ16562.1 - 0.00073 19.4 8.2 0.00073 19.4 8.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ16562.1 - 0.0015 18.6 4.0 0.0015 18.6 4.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAJ16562.1 - 0.011 15.5 7.6 0.011 15.5 7.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DEC-1_C PF04626.13 OAJ16562.1 - 0.032 14.6 4.6 0.079 13.4 4.6 1.6 1 0 0 1 1 1 0 Dec-1 protein, C terminal region zf-RING_4 PF14570.6 OAJ16562.1 - 0.049 13.4 7.0 0.11 12.3 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 OAJ16562.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAUS-augmin3 PF14932.6 OAJ16562.1 - 0.8 9.2 10.3 1.7 8.2 10.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 EzrA PF06160.12 OAJ16562.1 - 1 7.4 7.5 1.7 6.8 7.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-C3HC4_4 PF15227.6 OAJ16562.1 - 4 7.7 7.5 16 5.8 7.5 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2968 PF11180.8 OAJ16562.1 - 5.3 6.6 18.2 0.54 9.9 9.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) VTC PF09359.10 OAJ16563.1 - 4.9e-97 324.6 0.2 1.8e-96 322.8 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 OAJ16563.1 - 9.4e-19 68.6 24.9 1.1e-06 28.9 0.5 4.4 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 OAJ16563.1 - 3.7e-13 49.7 0.6 9e-13 48.5 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) RRM_1 PF00076.22 OAJ16587.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ16587.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif TPR_12 PF13424.6 OAJ16588.1 - 0.13 12.6 0.1 0.13 12.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ16588.1 - 0.16 11.9 1.1 4.5 7.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ16588.1 - 0.47 10.7 0.0 0.47 10.7 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec63 PF02889.16 OAJ16589.1 - 5e-68 229.0 0.0 7.6e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAJ16589.1 - 4e-38 130.9 1.2 2.5e-25 89.2 0.1 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 OAJ16589.1 - 7e-15 55.4 0.0 1.1e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ16589.1 - 4.4e-07 30.2 0.0 0.0028 18.0 0.0 4.4 4 2 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ16589.1 - 0.00032 21.0 0.2 0.03 14.6 0.1 3.6 3 1 0 3 3 3 1 AAA domain Helicase_PWI PF18149.1 OAJ16589.1 - 0.0057 16.8 0.0 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain T2SSE PF00437.20 OAJ16589.1 - 0.0073 15.4 0.0 0.77 8.8 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ16589.1 - 0.052 13.9 0.2 12 6.3 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain UvrD-helicase PF00580.21 OAJ16589.1 - 0.11 12.0 0.2 12 5.3 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf-RRN7 PF11781.8 OAJ16590.1 - 0.0022 17.6 0.1 0.0049 16.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 OAJ16590.1 - 0.027 14.7 0.2 0.055 13.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Med5 PF08689.10 OAJ16590.1 - 0.17 9.6 3.6 0.22 9.3 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF3759 PF12585.8 OAJ16591.1 - 4.9e-41 138.7 10.1 5.4e-41 138.5 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GTP_EFTU PF00009.27 OAJ16592.1 - 1.5e-55 187.8 0.1 2.5e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAJ16592.1 - 2.1e-13 50.1 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAJ16592.1 - 2.1e-08 34.2 0.0 4.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAJ16592.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAJ16592.1 - 0.018 14.8 0.1 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 OAJ16592.1 - 0.02 14.9 0.0 0.066 13.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M43 PF05572.13 OAJ16593.1 - 5.2e-19 68.7 1.8 6e-19 68.5 0.7 1.7 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ16593.1 - 4.6e-07 30.4 0.2 1.7e-05 25.3 0.0 2.3 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ16593.1 - 6e-05 23.3 5.8 8.5e-05 22.8 5.8 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAJ16593.1 - 0.0042 16.9 0.0 0.0057 16.5 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 OAJ16593.1 - 0.029 14.0 5.7 0.05 13.2 5.3 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Rax2 PF12768.7 OAJ16617.1 - 2.5e-37 128.5 0.7 3.2e-35 121.6 0.0 4.2 5 0 0 5 5 5 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 OAJ16617.1 - 9e-15 54.0 0.0 1.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ16617.1 - 4.7e-12 45.6 0.0 9.6e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ16617.1 - 9.9e-07 28.4 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OAJ16617.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Kelch_2 PF07646.15 OAJ16617.1 - 0.14 12.2 6.1 11 6.2 0.0 4.8 5 0 0 5 5 5 0 Kelch motif LapA_dom PF06305.11 OAJ16617.1 - 0.87 9.4 3.4 2.4 8.0 3.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DFP PF04127.15 OAJ16618.1 - 5.1e-20 72.1 0.0 3e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 OAJ16618.1 - 0.0021 18.5 0.0 0.088 13.2 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Amidase PF01425.21 OAJ16619.1 - 1.1e-57 196.0 0.0 2.7e-56 191.4 0.0 2.1 1 1 0 1 1 1 1 Amidase FtsJ PF01728.19 OAJ16620.1 - 2.9e-40 138.3 0.0 3.7e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase HSP9_HSP12 PF04119.12 OAJ16621.1 - 2.3e-18 66.3 5.7 2.3e-18 66.3 5.7 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 VIR_N PF15912.5 OAJ16621.1 - 0.014 15.1 0.3 0.018 14.7 0.3 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1744 PF08490.12 OAJ16622.1 - 1.2e-131 439.0 0.0 1.9e-131 438.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAJ16622.1 - 5.1e-78 262.6 0.0 8.4e-78 261.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAJ16622.1 - 1.3e-12 47.2 0.1 5e-11 42.0 0.2 3.1 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAJ16622.1 - 3e-09 36.9 0.1 9.9e-09 35.2 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAJ16622.1 - 1.6e-05 25.0 0.0 6.4e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily LPD14 PF18827.1 OAJ16622.1 - 0.1 12.8 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 HHH_3 PF12836.7 OAJ16622.1 - 0.17 12.2 0.0 0.69 10.2 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif IDO PF01231.18 OAJ16623.1 - 1.6e-40 139.2 0.0 2.6e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ubiquitin PF00240.23 OAJ16624.1 - 1.6e-08 34.2 0.1 2.6e-08 33.5 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ16624.1 - 1e-05 25.9 0.1 6.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OAJ16624.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OAJ16624.1 - 0.053 13.6 0.1 0.25 11.4 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain PI3K_rbd PF00794.18 OAJ16624.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain 3Beta_HSD PF01073.19 OAJ16646.1 - 7.9e-19 67.7 0.0 3.3e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ16646.1 - 6.9e-14 51.9 0.1 1.3e-13 51.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAJ16646.1 - 2.7e-12 46.4 0.8 8.1e-11 41.6 0.8 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAJ16646.1 - 4.6e-11 43.0 0.1 6.9e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAJ16646.1 - 4.8e-08 32.8 0.1 9.6e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAJ16646.1 - 1.3e-07 31.4 0.2 2.1e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAJ16646.1 - 2.2e-05 24.0 1.0 0.037 13.5 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAJ16646.1 - 6.4e-05 22.2 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 OAJ16646.1 - 0.0077 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ16646.1 - 0.0099 16.1 0.1 0.023 14.9 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAJ16646.1 - 0.041 13.8 0.5 0.76 9.7 0.5 2.2 1 1 0 1 1 1 0 KR domain RNase_PH PF01138.21 OAJ16647.1 - 1.3e-28 100.1 0.0 2.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 3HCDH_N PF02737.18 OAJ16648.1 - 1.4e-44 152.1 0.2 6.8e-44 149.9 0.2 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAJ16648.1 - 4.4e-35 120.2 0.0 9.3e-35 119.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2680 PF10925.8 OAJ16648.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF2813 PF11398.8 OAJ16648.1 - 0.22 10.8 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) FAD_binding_1 PF00667.20 OAJ16649.1 - 9.7e-55 185.5 0.0 1.4e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 OAJ16649.1 - 2.5e-06 27.7 0.0 9.3e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 OAJ16649.1 - 4.1e-06 27.4 0.0 1.7e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 OAJ16649.1 - 0.024 14.9 0.1 0.09 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II AP_endonuc_2 PF01261.24 OAJ16650.1 - 1.1e-14 54.3 0.0 4e-07 29.7 0.0 2.7 3 0 0 3 3 3 2 Xylose isomerase-like TIM barrel Proteasome PF00227.26 OAJ16651.1 - 1.3e-58 197.7 0.0 1.8e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ16651.1 - 9.9e-14 50.7 0.5 1.8e-13 49.9 0.2 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature LSM PF01423.22 OAJ16652.1 - 3.6e-14 52.2 0.1 4.6e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ16652.1 - 0.0039 17.3 0.0 0.0055 16.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAJ16652.1 - 0.042 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Aminotran_1_2 PF00155.21 OAJ16653.1 - 6.8e-44 150.5 0.0 6.7e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 OAJ16653.1 - 0.012 14.3 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OAJ16653.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ16653.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAJ16653.1 - 0.055 12.0 0.0 0.084 11.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L16 PF00252.18 OAJ16654.1 - 2.3e-41 140.9 0.0 3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L30_N PF08079.12 OAJ16655.1 - 3.5e-28 97.6 16.2 3.5e-28 97.6 16.2 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAJ16655.1 - 1.5e-16 60.0 1.9 1.6e-16 59.9 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.11 OAJ16655.1 - 0.083 13.2 0.7 0.15 12.4 0.7 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus DUF3419 PF11899.8 OAJ16656.1 - 5.1e-144 480.2 0.0 6.8e-144 479.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 OAJ16656.1 - 4.6e-09 36.9 0.0 1.1e-07 32.5 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ16656.1 - 7.4e-08 32.9 0.0 9.6e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16656.1 - 9.2e-08 32.1 0.0 4.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ16656.1 - 2.3e-07 30.4 0.0 4.9e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAJ16656.1 - 3e-07 30.4 0.0 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ16656.1 - 2.6e-05 24.9 0.0 8.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAJ16656.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 OAJ16656.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Glutaredoxin PF00462.24 OAJ16682.1 - 7.4e-18 64.5 0.0 1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OAJ16682.1 - 0.00046 20.5 0.0 0.00054 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OAJ16682.1 - 0.002 18.6 0.0 0.0045 17.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF953 PF06110.11 OAJ16682.1 - 0.0058 16.2 0.0 0.0067 16.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 OAJ16682.1 - 0.017 15.2 0.1 0.03 14.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 OAJ16682.1 - 0.038 14.1 0.2 7.3 6.7 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 OAJ16682.1 - 0.042 13.6 0.1 0.43 10.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TusA PF01206.17 OAJ16682.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA DnaJ PF00226.31 OAJ16684.1 - 0.00017 21.6 0.1 0.00028 20.9 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OAJ16684.1 - 0.00017 21.6 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF4781 PF16013.5 OAJ16684.1 - 0.15 10.9 0.3 0.23 10.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DPBB_1 PF03330.18 OAJ16685.1 - 7.5e-05 22.9 0.1 0.00019 21.6 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Gon7 PF08738.10 OAJ16685.1 - 0.0081 16.2 3.5 0.0081 16.2 3.5 1.9 2 0 0 2 2 2 1 Gon7 family SPESP1 PF15754.5 OAJ16685.1 - 0.16 11.2 11.2 0.21 10.8 11.2 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 SOG2 PF10428.9 OAJ16685.1 - 0.16 11.2 8.0 0.21 10.8 8.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2868 PF11067.8 OAJ16685.1 - 0.28 10.6 3.0 0.4 10.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TonB_N PF16031.5 OAJ16685.1 - 1.2 9.6 25.6 2.6 8.6 25.6 1.5 1 0 0 1 1 1 0 TonB polyproline region Menin PF05053.13 OAJ16685.1 - 2.7 6.3 10.0 3.8 5.8 10.0 1.2 1 0 0 1 1 1 0 Menin Lin-8 PF03353.15 OAJ16685.1 - 3.4 7.1 8.9 4.6 6.7 8.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mucin PF01456.17 OAJ16685.1 - 4.3 7.3 18.4 11 6.0 18.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIE-A_C PF11521.8 OAJ16685.1 - 5.7 7.3 14.4 1.5 9.2 1.1 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Apt1 PF10351.9 OAJ16685.1 - 7.2 5.3 13.4 9.3 5.0 13.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM154 PF15102.6 OAJ16685.1 - 8.4 6.3 8.9 18 5.3 8.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family Myb_DNA-binding PF00249.31 OAJ16687.1 - 1.1e-34 118.3 4.3 8.3e-12 45.1 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ16687.1 - 5.1e-28 97.1 0.0 1.6e-11 44.3 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OAJ16687.1 - 0.0008 19.4 2.6 2.6 8.2 1.2 3.2 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OAJ16687.1 - 0.0034 17.2 0.1 0.12 12.3 0.0 2.6 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OAJ16687.1 - 0.094 12.9 0.1 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 OAJ16687.1 - 0.18 11.9 0.0 3.2 7.8 0.0 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) WD40 PF00400.32 OAJ16688.1 - 1.2e-25 89.2 0.2 4.5e-06 27.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16688.1 - 1.3e-09 38.3 0.0 0.0015 18.8 0.2 4.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ16688.1 - 0.0024 16.6 0.1 0.0042 15.8 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 OAJ16688.1 - 0.09 11.8 0.3 6.4 5.7 0.0 2.7 2 1 1 3 3 3 0 Coatomer WD associated region WD40_like PF17005.5 OAJ16688.1 - 0.2 11.0 0.0 2.3 7.4 0.0 2.6 3 1 1 4 4 4 0 WD40-like domain Ge1_WD40 PF16529.5 OAJ16688.1 - 0.27 10.1 1.3 4.5 6.1 0.3 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Aminotran_1_2 PF00155.21 OAJ16689.1 - 2e-15 56.9 0.0 2.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAJ16689.1 - 8.8e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_Tnp_Tc5 PF03221.16 OAJ16690.1 - 9.7e-11 41.5 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3040 PF11239.8 OAJ16690.1 - 0.16 12.3 0.2 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) EXS PF03124.14 OAJ16691.1 - 3.4e-73 246.9 7.8 8.3e-63 212.7 4.9 2.3 2 0 0 2 2 2 2 EXS family MMgT PF10270.9 OAJ16718.1 - 3.1e-14 53.1 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Sugar_tr PF00083.24 OAJ16720.1 - 6.3e-67 226.4 11.3 7.4e-67 226.1 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ16720.1 - 1.2e-12 47.5 21.0 1.2e-12 47.5 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ham1p_like PF01725.16 OAJ16721.1 - 2e-59 200.7 0.0 2.2e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family PIF1 PF05970.14 OAJ16722.1 - 1.9e-104 349.8 0.0 2.6e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ16722.1 - 1.5e-58 198.2 0.1 3.1e-58 197.2 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ16722.1 - 1.1e-09 38.3 0.1 2e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 OAJ16722.1 - 8.6e-08 30.6 0.0 4.4e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 OAJ16722.1 - 0.0023 17.7 0.0 0.0058 16.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 OAJ16722.1 - 0.011 16.1 0.0 0.064 13.6 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OAJ16722.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAJ16722.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein Cation_efflux PF01545.21 OAJ16724.1 - 3.8e-49 167.1 12.6 9.4e-49 165.9 12.6 1.6 1 1 0 1 1 1 1 Cation efflux family NUP50 PF08911.11 OAJ16726.1 - 3e-06 27.8 0.1 3e-06 27.8 0.1 5.9 5 3 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) DUF4632 PF15451.6 OAJ16726.1 - 0.02 14.9 0.1 0.02 14.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4632) Cwf_Cwc_15 PF04889.12 OAJ16726.1 - 0.59 9.8 8.5 1.3 8.7 8.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S9 PF00326.21 OAJ16745.1 - 1.6e-06 27.8 0.1 3.9e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ16745.1 - 0.0012 18.2 0.1 0.0053 16.0 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ16745.1 - 0.011 15.5 0.1 0.028 14.1 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 OAJ16745.1 - 0.048 12.8 0.1 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) NDC10_II PF16787.5 OAJ16746.1 - 5.3e-13 48.7 0.0 7.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ16746.1 - 0.00089 19.5 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SSP160 PF06933.11 OAJ16746.1 - 2.4 6.3 12.1 3.5 5.7 12.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dimer_Tnp_hAT PF05699.14 OAJ16747.1 - 1.7e-05 24.5 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5313 PF17240.2 OAJ16748.1 - 0.038 14.4 0.3 0.06 13.8 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Nnf1 PF03980.14 OAJ16748.1 - 0.088 13.2 1.8 0.13 12.6 1.8 1.2 1 0 0 1 1 1 0 Nnf1 DUF5635 PF18685.1 OAJ16748.1 - 3.1 7.8 5.3 1.5 8.8 0.9 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5635) HTH_Tnp_1_2 PF13022.6 OAJ16750.1 - 0.12 12.6 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_17 PF12728.7 OAJ16750.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Lectin_leg-like PF03388.13 OAJ16779.1 - 1.1e-59 201.7 0.1 1.4e-59 201.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family DUF3561 PF12084.8 OAJ16779.1 - 0.016 15.2 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Lectin_legB PF00139.19 OAJ16779.1 - 0.055 13.0 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain Pribosyltran_N PF13793.6 OAJ16780.1 - 6.8e-43 145.3 0.4 4.4e-42 142.7 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAJ16780.1 - 9.1e-41 139.9 2.1 3.9e-33 115.0 0.1 3.0 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAJ16780.1 - 9.8e-15 54.4 0.1 7.4e-14 51.6 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Nup160 PF11715.8 OAJ16781.1 - 1.2e-17 63.8 0.0 3.8e-10 39.1 0.0 3.2 2 1 0 2 2 2 2 Nucleoporin Nup120/160 FA_hydroxylase PF04116.13 OAJ16782.1 - 1.3e-18 67.6 6.3 1.3e-18 67.6 6.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF515 PF04415.12 OAJ16783.1 - 8.8 4.6 16.3 11 4.3 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Polysacc_deac_1 PF01522.21 OAJ16784.1 - 6.2e-23 81.0 0.0 1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 OAJ16784.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Virulence protein nec1 Polysacc_deac_1 PF01522.21 OAJ16785.1 - 1.2e-23 83.3 0.1 5.3e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 OAJ16785.1 - 0.17 10.0 11.5 0.24 9.5 11.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 OAJ16785.1 - 7.4 4.6 23.6 11 4.0 23.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IATP PF04568.12 OAJ16785.1 - 7.8 7.0 6.0 16 6.0 6.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Peptidase_S10 PF00450.22 OAJ16786.1 - 2.2e-110 369.9 1.3 3e-110 369.5 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Apolipoprotein PF01442.18 OAJ16786.1 - 0.00063 19.7 0.2 0.00095 19.1 0.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OAJ16786.1 - 0.025 14.6 1.0 0.05 13.6 1.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1104 PF06518.11 OAJ16786.1 - 0.14 12.6 0.9 0.34 11.3 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DEAD PF00270.29 OAJ16787.1 - 3.5e-12 46.4 0.0 6.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ16787.1 - 2.9e-08 34.0 0.1 5.8e-06 26.6 0.1 2.4 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ16787.1 - 0.037 14.0 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrbL PF04610.14 OAJ16788.1 - 0.052 13.3 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Rib_5-P_isom_A PF06026.14 OAJ16817.1 - 1.9e-60 203.4 0.0 3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 OAJ16817.1 - 0.052 13.5 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Cellulase PF00150.18 OAJ16818.1 - 8.2e-12 45.1 0.1 1.8e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GREB1 PF15782.5 OAJ16819.1 - 8 3.4 7.0 9.2 3.2 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Bin3 PF06859.12 OAJ16821.1 - 3.2e-17 63.1 0.0 1.5e-13 51.3 0.0 3.0 1 1 0 2 2 2 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 OAJ16821.1 - 0.00038 21.1 0.0 0.0011 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ16821.1 - 0.00069 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ16821.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16821.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.8 OAJ16821.1 - 5.6 7.3 12.0 0.57 10.5 1.6 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain RRM_1 PF00076.22 OAJ16822.1 - 4.5e-09 36.0 0.0 7.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N_2 PF16884.5 OAJ16823.1 - 9.9e-34 115.5 0.0 2e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAJ16823.1 - 2.1e-18 66.5 0.0 3.5e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ16823.1 - 2.5e-08 35.0 0.0 1.1e-07 32.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAJ16823.1 - 0.0072 15.8 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAJ16823.1 - 0.0088 15.5 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ELFV_dehydrog PF00208.21 OAJ16823.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glycos_transf_1 PF00534.20 OAJ16824.1 - 1.5e-18 67.0 0.0 7.3e-13 48.4 0.0 3.3 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ16824.1 - 5.6e-09 36.2 0.7 4.9e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAJ16824.1 - 0.00011 22.6 2.8 0.00017 22.1 0.0 2.6 3 1 0 3 3 3 1 Glycosyl transferases group 1 ALG11_N PF15924.5 OAJ16824.1 - 0.0021 18.2 0.0 0.022 14.8 0.0 2.3 3 0 0 3 3 3 1 ALG11 mannosyltransferase N-terminus Glyco_trans_4_4 PF13579.6 OAJ16824.1 - 0.0071 16.8 0.3 0.0071 16.8 0.3 2.7 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Spem1 PF15670.5 OAJ16824.1 - 0.068 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 Ndc1_Nup PF09531.10 OAJ16825.1 - 6.2 5.4 9.1 8.1 5.0 9.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prenylcys_lyase PF07156.14 OAJ16826.1 - 1.1e-62 212.2 0.0 1.1e-60 205.7 0.0 2.8 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 OAJ16826.1 - 1.3e-10 41.3 0.2 6.1e-10 39.2 0.2 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ16826.1 - 5.9e-05 22.4 0.1 0.0001 21.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ16826.1 - 0.00015 21.5 0.2 0.00031 20.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ16826.1 - 0.0024 17.9 0.2 0.047 13.7 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAJ16826.1 - 0.0025 17.2 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAJ16826.1 - 0.012 15.0 1.8 0.016 14.5 1.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ16826.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 OAJ16826.1 - 0.035 13.2 3.1 0.022 13.9 1.1 1.6 2 0 0 2 2 2 0 FAD binding domain TAFII28 PF04719.14 OAJ16826.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region HI0933_like PF03486.14 OAJ16826.1 - 0.063 12.0 0.1 0.089 11.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAJ16826.1 - 0.23 10.5 4.1 0.42 9.7 1.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A SEN1_N PF12726.7 OAJ16853.1 - 4.4e-79 266.6 3.6 1.5e-78 264.9 3.6 1.9 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAJ16853.1 - 5.3e-69 232.9 3.7 5.3e-69 232.9 3.7 2.5 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 OAJ16853.1 - 1.1e-59 201.4 0.0 1.1e-58 198.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ16853.1 - 1.5e-10 41.6 4.9 6.9e-10 39.4 2.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ16853.1 - 1.7e-09 37.7 0.5 7.3e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAJ16853.1 - 2.6e-05 24.1 0.0 1.4 8.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAJ16853.1 - 5.1e-05 22.9 1.3 5.1e-05 22.9 1.3 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OAJ16853.1 - 0.0066 16.5 0.8 0.051 13.6 0.8 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HAUS6_N PF14661.6 OAJ16853.1 - 0.074 12.6 7.2 0.27 10.8 7.2 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_6 PF12774.7 OAJ16853.1 - 0.16 10.9 0.4 0.81 8.6 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 OAJ16853.1 - 0.6 10.5 4.0 0.75 10.2 1.7 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Med9 PF07544.13 OAJ16853.1 - 0.74 9.9 7.1 2.9 8.0 7.1 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NIR_SIR PF01077.22 OAJ16854.1 - 4.4e-46 156.3 0.0 3.3e-39 133.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAJ16854.1 - 3.2e-28 97.4 0.0 3.6e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAJ16854.1 - 1.6e-26 93.2 0.0 3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAJ16854.1 - 3.6e-09 36.7 0.1 3.6e-09 36.7 0.1 2.5 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg T3SSipB PF16535.5 OAJ16854.1 - 0.0011 19.5 2.0 0.0011 19.5 2.0 2.3 2 0 0 2 2 2 1 Type III cell invasion protein SipB adh_short PF00106.25 OAJ16855.1 - 4e-09 36.2 0.0 6.3e-05 22.5 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ16855.1 - 0.00033 20.3 0.0 0.0044 16.6 0.0 2.3 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ16855.1 - 0.0055 16.2 0.0 1.4 8.4 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ16855.1 - 0.13 11.6 0.0 5 6.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase HsbA PF12296.8 OAJ16856.1 - 2.7e-06 27.8 12.2 0.00056 20.3 0.1 2.8 2 1 1 3 3 3 2 Hydrophobic surface binding protein A Apolipoprotein PF01442.18 OAJ16856.1 - 0.018 14.9 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5481 PF17578.2 OAJ16856.1 - 0.12 12.8 0.3 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5481) Toprim_N PF08275.11 OAJ16857.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain TetR_C_25 PF17933.1 OAJ16857.1 - 0.19 12.1 0.2 2.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GST_N PF02798.20 OAJ16858.1 - 1.4e-16 60.6 0.0 3.2e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ16858.1 - 8.4e-16 58.1 0.0 2.2e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ16858.1 - 1.2e-10 41.5 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OAJ16858.1 - 0.00052 20.7 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OAJ16858.1 - 0.004 17.5 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF1729 PF08354.10 OAJ16860.1 - 2e-45 155.2 0.0 3.2e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_meander PF17951.1 OAJ16860.1 - 8.6e-25 87.3 0.8 7.3e-13 48.6 0.0 2.5 2 1 1 3 3 3 2 Fatty acid synthase meander beta sheet domain Cpn60_TCP1 PF00118.24 OAJ16887.1 - 1.9e-159 531.4 3.2 4.6e-104 348.8 0.1 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF1572 PF07609.11 OAJ16887.1 - 0.11 12.2 0.0 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1572) HLH PF00010.26 OAJ16889.1 - 1.1e-12 47.6 0.0 6.2e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain SHE3 PF17078.5 OAJ16890.1 - 1.8e-08 34.4 1.2 3.3e-08 33.5 1.2 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Cep57_CLD_2 PF14197.6 OAJ16890.1 - 0.012 15.7 5.4 0.012 15.7 5.4 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FPP PF05911.11 OAJ16890.1 - 0.028 12.6 6.5 0.2 9.8 1.3 2.4 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil EzrA PF06160.12 OAJ16890.1 - 0.036 12.3 2.8 1 7.5 0.1 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA THOC7 PF05615.13 OAJ16890.1 - 0.086 13.1 0.2 0.086 13.1 0.2 3.7 3 1 2 5 5 5 0 Tho complex subunit 7 COG5 PF10392.9 OAJ16890.1 - 0.12 12.6 2.4 15 5.7 0.9 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Filament PF00038.21 OAJ16890.1 - 0.31 10.6 18.7 1.3 8.5 3.5 3.2 2 1 1 3 3 3 0 Intermediate filament protein DUF4201 PF13870.6 OAJ16890.1 - 0.95 9.2 5.7 0.56 9.9 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 OAJ16890.1 - 2 8.4 6.1 2.7 8.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAJ16890.1 - 4.1 6.2 15.3 0.15 10.9 1.2 3.1 2 1 0 3 3 3 0 Spc7 kinetochore protein K_oxygenase PF13434.6 OAJ16891.1 - 8.7e-08 31.7 0.0 0.0043 16.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAJ16891.1 - 0.0026 17.1 0.1 1.5 7.9 0.0 3.2 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ16891.1 - 0.33 9.9 0.0 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TAF8_C PF10406.9 OAJ16893.1 - 5e-09 36.6 5.9 1e-06 29.2 4.2 3.1 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term PBP1_TM PF14812.6 OAJ16893.1 - 0.037 14.4 7.6 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Striatin PF08232.12 OAJ16893.1 - 0.5 10.9 3.6 0.95 10.0 3.6 1.4 1 0 0 1 1 1 0 Striatin family LNS2 PF08235.13 OAJ16894.1 - 4.1e-97 324.1 0.0 1.2e-75 253.9 0.0 2.1 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAJ16894.1 - 2.1e-30 104.7 0.1 1.1e-19 70.3 0.0 2.5 2 0 0 2 2 2 2 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 OAJ16894.1 - 0.0098 15.5 0.0 0.048 13.2 0.0 2.0 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Bd3614-deam PF14439.6 OAJ16894.1 - 0.049 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase WRNPLPNID PF15017.6 OAJ16894.1 - 0.1 13.5 0.0 0.1 13.5 0.0 2.4 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box zf-H2C2 PF09337.10 OAJ16894.1 - 0.19 11.9 0.1 0.5 10.6 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Transferase PF02458.15 OAJ16895.1 - 8.1e-08 31.3 0.0 3.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Transferase family OAM_dimer PF16554.5 OAJ16922.1 - 0.00014 22.3 4.9 0.086 13.3 0.0 2.8 3 0 0 3 3 3 2 Dimerisation domain of d-ornithine 4,5-aminomutase DUF1658 PF07871.11 OAJ16922.1 - 0.43 10.6 3.1 72 3.6 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1658) Herpes_U59 PF04529.12 OAJ16923.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein 2OG-FeII_Oxy_3 PF13640.6 OAJ16925.1 - 3e-05 24.8 0.3 6.6e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF494 PF04361.13 OAJ16926.1 - 0.045 13.6 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) ANAPC5 PF12862.7 OAJ16926.1 - 0.057 13.5 0.3 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Imm6 PF14434.6 OAJ16926.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Immunity protein Imm6 zf-RanBP PF00641.18 OAJ16928.1 - 1.1e-11 43.8 10.8 4.8e-07 29.0 0.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DnaJ_C PF01556.18 OAJ16953.1 - 3.2e-36 124.6 0.0 4.4e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ16953.1 - 3.5e-22 78.3 4.2 5.5e-22 77.7 4.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ16953.1 - 2.5e-09 37.4 17.9 3.2e-09 37.0 16.3 2.0 2 0 0 2 2 2 1 DnaJ central domain Binary_toxB PF03495.14 OAJ16953.1 - 0.19 12.0 0.8 7.6 6.8 0.3 2.6 2 1 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Anti-TRAP PF15777.5 OAJ16953.1 - 6.2 6.9 17.0 0.36 10.8 3.7 3.4 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Peptidase_C48 PF02902.19 OAJ16954.1 - 1.6e-25 90.2 0.0 4.6e-25 88.7 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SUR7 PF06687.12 OAJ16955.1 - 2.7e-21 76.2 4.4 3.4e-21 75.8 4.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family Ost5 PF05251.12 OAJ16955.1 - 0.85 9.9 12.5 0.28 11.5 7.9 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF2207 PF09972.9 OAJ16955.1 - 2.4 6.8 6.0 3.6 6.2 6.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Cellulase PF00150.18 OAJ16957.1 - 4.4e-10 39.5 2.1 9.1e-10 38.4 2.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5337 PF17272.2 OAJ16957.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Zip PF02535.22 OAJ16980.1 - 5.6e-28 98.1 22.0 1.1e-20 74.2 1.8 3.9 4 1 0 4 4 4 3 ZIP Zinc transporter FGF PF00167.18 OAJ16980.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor ATE_C PF04377.15 OAJ16980.1 - 0.12 12.9 0.0 0.58 10.8 0.0 1.9 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus FH2 PF02181.23 OAJ16981.1 - 1.2e-64 218.8 4.0 1.2e-64 218.8 4.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OAJ16981.1 - 1.5e-44 151.8 0.0 1.5e-44 151.8 0.0 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAJ16981.1 - 2.8e-42 144.6 0.3 4e-41 140.8 0.0 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain HD_5 PF13487.6 OAJ16981.1 - 0.038 14.2 0.1 1 9.7 0.1 2.7 2 0 0 2 2 2 0 HD domain G-gamma PF00631.22 OAJ16981.1 - 1.5 8.9 4.4 1.3 9.1 0.2 2.8 2 0 0 2 2 2 0 GGL domain TPR_2 PF07719.17 OAJ16982.1 - 1.1e-07 31.4 4.8 0.11 12.7 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ16982.1 - 5.1e-07 29.2 2.3 0.13 12.2 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ16982.1 - 0.0006 20.4 12.5 0.0021 18.7 2.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANTAR PF03861.14 OAJ16982.1 - 0.0052 16.6 1.0 0.023 14.6 0.0 2.5 2 0 0 2 2 2 1 ANTAR domain TPR_11 PF13414.6 OAJ16982.1 - 0.009 15.7 0.7 0.32 10.7 0.1 2.7 2 0 0 2 2 2 1 TPR repeat zf-RING_4 PF14570.6 OAJ16982.1 - 0.096 12.5 0.7 0.2 11.4 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.6 OAJ16982.1 - 8.8 5.6 21.2 46 3.2 17.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Sfi1 PF08457.10 OAJ16983.1 - 3.4e-11 42.4 85.7 2.3e-05 23.1 29.8 5.9 1 1 3 4 4 4 4 Sfi1 spindle body protein Arm PF00514.23 OAJ16984.1 - 0.0013 18.7 6.5 0.034 14.2 0.1 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Exo_endo_phos PF03372.23 OAJ16985.1 - 7.3e-06 25.7 0.0 2.6e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RPN2_C PF18004.1 OAJ16985.1 - 1.3 8.9 4.9 0.48 10.3 0.6 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 OAJ16985.1 - 2.1 8.1 6.6 5 6.9 1.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 OAJ16985.1 - 5.5 6.3 8.4 0.84 9.0 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PFK PF00365.20 OAJ16986.1 - 2.3e-184 611.2 0.2 1.8e-102 342.5 0.2 2.6 2 1 0 2 2 2 2 Phosphofructokinase DUF308 PF03729.13 OAJ16986.1 - 0.28 11.5 1.4 5.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Dimer_Tnp_hAT PF05699.14 OAJ17011.1 - 1.9e-26 91.6 0.2 2.3e-26 91.4 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEC-1_N PF04625.13 OAJ17013.1 - 0.042 12.9 2.3 0.064 12.3 2.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TFIIA PF03153.13 OAJ17015.1 - 0.013 15.6 10.4 0.014 15.4 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 OAJ17015.1 - 0.015 15.2 3.2 0.018 15.0 3.2 1.1 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.9 OAJ17015.1 - 0.28 9.4 7.4 0.26 9.5 7.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 OAJ17015.1 - 0.51 9.1 5.4 0.57 9.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pex14_N PF04695.13 OAJ17015.1 - 1.6 9.4 17.4 3.4 8.3 17.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.6 OAJ17015.1 - 4.7 6.3 20.5 7.3 5.7 20.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MULE PF10551.9 OAJ17016.1 - 1.3e-11 44.8 0.6 2.2e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OAJ17016.1 - 0.0022 18.0 0.1 0.0041 17.1 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase AMP-binding PF00501.28 OAJ17017.1 - 3.7e-82 276.2 0.0 4.6e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Collagen PF01391.18 OAJ17018.1 - 1.4e-46 156.0 258.6 1.8e-09 37.2 31.0 8.0 3 2 5 8 8 8 8 Collagen triple helix repeat (20 copies) GATase_6 PF13522.6 OAJ17049.1 - 1.3e-14 54.5 0.0 3.3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ17049.1 - 1.4e-10 41.2 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAJ17049.1 - 2.5e-09 36.9 0.2 4.2e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OAJ17049.1 - 7.4e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Alpha_E2_glycop PF00943.19 OAJ17050.1 - 0.082 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Histone PF00125.24 OAJ17051.1 - 3.3e-15 56.6 0.0 4.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAJ17051.1 - 2.5e-09 36.7 0.1 4.2e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAJ17051.1 - 9.2e-06 25.9 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 OAJ17052.1 - 0.15 11.4 13.1 0.21 10.9 13.1 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 OAJ17052.1 - 0.24 10.0 8.8 0.36 9.4 8.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 OAJ17052.1 - 0.24 10.8 10.0 0.32 10.4 10.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 OAJ17052.1 - 0.26 10.4 16.2 0.48 9.5 16.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OAJ17052.1 - 0.31 9.1 11.9 0.39 8.8 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ17052.1 - 0.4 8.8 9.3 0.5 8.5 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ17052.1 - 1.6 6.9 6.0 2 6.6 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 OAJ17052.1 - 1.6 5.7 3.7 2.1 5.3 3.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4820 PF16091.5 OAJ17052.1 - 3 7.2 6.7 0.19 11.1 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RSN1_7TM PF02714.15 OAJ17053.1 - 2.4e-58 197.6 20.9 3.8e-58 197.0 20.9 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAJ17053.1 - 1.9e-21 76.4 0.3 1.9e-21 76.4 0.3 2.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAJ17053.1 - 1.7e-19 70.7 0.0 4e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DUF4611 PF15387.6 OAJ17053.1 - 9.7 6.5 10.1 1.6 9.0 2.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) EF-hand_4 PF12763.7 OAJ17054.1 - 5.1e-34 116.3 0.0 1.3e-14 53.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAJ17054.1 - 1e-06 29.1 0.0 0.046 14.2 0.0 4.0 3 1 1 4 4 4 3 EF-hand domain pair ATG16 PF08614.11 OAJ17054.1 - 8.8e-05 22.8 0.2 8.8e-05 22.8 0.2 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) EF-hand_1 PF00036.32 OAJ17054.1 - 0.0077 15.7 3.4 4.2 7.2 0.0 4.0 4 0 0 4 4 4 1 EF hand DUF4472 PF14739.6 OAJ17054.1 - 0.023 15.4 1.5 0.039 14.7 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Spc7 PF08317.11 OAJ17054.1 - 1.2 8.0 4.0 1.6 7.5 4.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 OAJ17054.1 - 1.6 8.8 11.4 2.8 8.0 11.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 OAJ17054.1 - 1.8 8.8 9.6 8.2 6.8 3.3 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4140 PF13600.6 OAJ17054.1 - 5.6 7.5 7.4 4e+02 1.5 7.4 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.20 OAJ17055.1 - 3.3e-18 65.6 0.5 4.7e-18 65.1 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit GlnE PF03710.15 OAJ17055.1 - 0.01 15.3 1.2 0.011 15.1 1.2 1.1 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DUF4407 PF14362.6 OAJ17055.1 - 0.4 10.0 6.5 0.49 9.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTA_holin_3TM PF11351.8 OAJ17055.1 - 2.7 8.5 5.8 0.6 10.7 2.3 1.6 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Tetraspanin PF00335.20 OAJ17056.1 - 4.5e-05 23.3 12.6 7.9e-05 22.5 12.6 1.4 1 1 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.15 OAJ17056.1 - 5.8 6.5 8.9 2.8 7.5 2.4 2.4 1 1 1 2 2 2 0 O-Antigen ligase DUF5060 PF16586.5 OAJ17058.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) DNA_pol_viral_C PF00336.18 OAJ17083.1 - 0.0043 16.5 0.1 0.0092 15.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain TAF4 PF05236.14 OAJ17084.1 - 0.029 14.1 2.2 0.036 13.8 2.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-CCHC PF00098.23 OAJ17084.1 - 0.033 14.3 1.3 0.033 14.3 1.3 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ17084.1 - 3.8 7.3 9.5 1 9.1 1.8 2.4 2 0 0 2 2 2 0 Zinc knuckle LUC7 PF03194.15 OAJ17112.1 - 4.9e-71 239.3 2.3 7.5e-71 238.7 2.3 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Prenyltrans PF00432.21 OAJ17113.1 - 1.7e-36 123.6 12.2 6.4e-12 45.0 0.2 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAJ17113.1 - 0.066 12.3 0.1 1.3 8.0 0.1 2.8 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain Thiamine_BP PF01910.17 OAJ17114.1 - 6.5e-21 74.1 0.0 8e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 OAJ17114.1 - 0.005 17.3 0.0 0.0073 16.8 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family Ceramidase PF05875.12 OAJ17115.1 - 4.3e-70 236.1 4.6 5e-70 235.9 4.6 1.0 1 0 0 1 1 1 1 Ceramidase DASH_Dad4 PF08650.10 OAJ17116.1 - 1.5e-24 85.7 0.0 1.9e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 OAJ17116.1 - 0.015 15.5 0.2 0.019 15.1 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 PRMT5 PF05185.16 OAJ17117.1 - 4.8e-58 195.8 0.0 7.6e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 OAJ17117.1 - 5.5e-58 196.2 0.0 8.9e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 OAJ17117.1 - 8e-52 175.7 0.0 1.1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 OAJ17117.1 - 0.00055 20.6 0.0 0.0018 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ17117.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ17117.1 - 0.013 16.1 0.0 0.041 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 OAJ17118.1 - 0.017 15.0 1.5 0.28 11.1 0.2 2.6 2 0 0 2 2 2 0 F-box-like ADH_N PF08240.12 OAJ17119.1 - 5.7e-31 106.6 0.2 1e-30 105.8 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ17119.1 - 3.5e-25 88.5 0.1 5.5e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ17119.1 - 9e-06 25.3 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAJ17119.1 - 2.2e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAJ17119.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.6 OAJ17119.1 - 0.0026 18.8 0.0 0.0048 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAJ17119.1 - 0.0026 18.4 0.0 0.0063 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 OAJ17119.1 - 0.0032 17.7 0.2 0.0058 16.9 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_N_assoc PF13823.6 OAJ17119.1 - 0.14 12.1 1.1 0.37 10.8 1.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Ssu72 PF04722.13 OAJ17122.1 - 2.9e-85 284.7 0.0 3.3e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DNA_repr_REX1B PF14966.6 OAJ17123.1 - 0.0014 19.2 2.5 0.14 12.9 0.1 3.1 2 1 0 2 2 2 1 DNA repair REX1-B ARA70 PF12489.8 OAJ17123.1 - 0.069 13.3 0.2 0.069 13.3 0.2 1.8 2 1 0 2 2 2 0 Nuclear coactivator DUF5132 PF17195.4 OAJ17123.1 - 0.33 11.1 2.6 0.79 9.9 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) PTPRCAP PF15713.5 OAJ17123.1 - 0.33 11.2 8.1 0.19 12.0 0.7 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated GvpL_GvpF PF06386.11 OAJ17123.1 - 1.6 8.6 8.9 0.3 11.0 5.3 1.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF SET PF00856.28 OAJ17124.1 - 0.0029 18.0 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 SET domain Methyltransf_13 PF08421.11 OAJ17124.1 - 0.094 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative zinc binding domain HMG_box PF00505.19 OAJ17125.1 - 7.2e-14 52.0 1.7 7.9e-14 51.8 0.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ17125.1 - 1.2e-09 38.6 0.2 2.7e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain STG PF15809.5 OAJ17147.1 - 0.019 15.0 1.5 0.025 14.7 1.5 1.2 1 0 0 1 1 1 0 Simian taste bud-specific gene product family Iso_dh PF00180.20 OAJ17148.1 - 2.4e-71 240.7 0.0 2.9e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SR-25 PF10500.9 OAJ17148.1 - 9.3 5.8 6.9 18 4.9 6.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M3 PF01432.20 OAJ17149.1 - 1.9e-129 432.9 0.0 2.5e-129 432.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 OAJ17149.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Effector protein Glycos_transf_2 PF00535.26 OAJ17150.1 - 9.9e-22 77.5 0.0 7.6e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAJ17150.1 - 8.6e-07 29.1 0.0 0.00076 19.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Mss4 PF04421.13 OAJ17151.1 - 1.4e-11 44.4 0.3 7.2e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.25 OAJ17151.1 - 0.00044 20.5 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ17151.1 - 0.2 12.1 0.1 1.1 9.8 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain SHR3_chaperone PF08229.11 OAJ17152.1 - 4.6e-36 123.6 0.0 7e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 Med21 PF11221.8 OAJ17152.1 - 1.2 9.4 3.9 1.9 8.7 3.9 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF676 PF05057.14 OAJ17153.1 - 2.7e-29 102.3 0.0 4.9e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) GREB1 PF15782.5 OAJ17153.1 - 0.013 12.7 1.8 0.017 12.3 1.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RVT_1 PF00078.27 OAJ17154.1 - 2.9e-13 49.9 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.23 OAJ17155.1 - 3.7e-61 206.8 0.0 1.5e-59 201.5 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ17155.1 - 8.8e-22 77.6 0.2 5.8e-20 71.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ17155.1 - 7.7e-09 35.8 0.0 3.3e-08 33.7 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ17155.1 - 3.5e-08 33.0 0.4 1.3e-06 27.8 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 E1_dh PF00676.20 OAJ17155.1 - 0.031 13.2 1.2 0.053 12.5 1.2 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF676 PF05057.14 OAJ17156.1 - 9.9e-27 93.9 0.0 1.9e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAJ17156.1 - 0.0077 16.9 1.2 0.0077 16.9 1.2 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ17156.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein NUC173 PF08161.12 OAJ17179.1 - 1.8e-46 158.4 0.1 8.7e-46 156.2 0.0 2.3 2 0 0 2 2 2 1 NUC173 domain MMS19_C PF12460.8 OAJ17179.1 - 0.0015 17.7 20.4 0.0052 16.0 3.0 3.5 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal MFMR PF07777.11 OAJ17179.1 - 1.7 9.2 3.2 3.7 8.1 0.0 3.1 4 0 0 4 4 4 0 G-box binding protein MFMR CDC73_C PF05179.14 OAJ17180.1 - 2.9e-45 153.8 0.0 9.4e-31 106.6 0.3 2.2 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 OAJ17180.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal HMGL-like PF00682.19 OAJ17181.1 - 3.4e-81 272.7 0.5 6.2e-81 271.8 0.5 1.4 1 0 0 1 1 1 1 HMGL-like GAD PF02938.14 OAJ17181.1 - 0.066 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 GAD domain Utp14 PF04615.13 OAJ17183.1 - 1.9e-171 572.4 38.3 1.9e-171 572.4 38.3 2.6 1 1 1 2 2 2 1 Utp14 protein UPF0113_N PF17833.1 OAJ17184.1 - 4.6e-27 94.4 0.0 6.9e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OAJ17184.1 - 2.9e-23 81.9 0.0 4.5e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 OAJ17184.1 - 0.051 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain PI3_PI4_kinase PF00454.27 OAJ17185.1 - 4.6e-34 118.3 0.0 9.8e-32 110.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAJ17185.1 - 2.4e-26 92.3 0.2 7.9e-26 90.6 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Thioredoxin PF00085.20 OAJ17210.1 - 9.1e-21 73.8 0.0 1.2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ17210.1 - 1.4e-05 25.4 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 OAJ17210.1 - 0.017 15.3 0.1 0.13 12.5 0.4 1.9 1 1 1 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 OAJ17210.1 - 0.089 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 OAJ17210.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OAJ17210.1 - 0.22 11.8 0.5 1.3 9.4 0.1 2.2 2 1 1 3 3 3 0 Thioredoxin-like Ribosomal_L34e PF01199.18 OAJ17211.1 - 2.2e-43 146.4 3.5 2.9e-43 146.1 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.6 OAJ17211.1 - 0.0093 15.9 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c FhuF_C PF11575.8 OAJ17211.1 - 0.028 14.3 2.1 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF2199 PF09965.9 OAJ17211.1 - 0.046 13.8 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) DAGK_cat PF00781.24 OAJ17212.1 - 1.5e-21 76.3 0.1 3.1e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TFIIF_alpha PF05793.12 OAJ17213.1 - 0.00048 18.9 0.0 0.00048 18.9 0.0 5.1 4 1 0 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Endostatin PF06482.11 OAJ17214.1 - 0.86 9.0 19.4 0.11 12.0 9.6 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF2052 PF09747.9 OAJ17214.1 - 1.3 9.2 21.0 2.8 8.0 10.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Asparaginase_2 PF01112.18 OAJ17214.1 - 2 7.4 6.4 0.22 10.5 2.0 1.6 2 0 0 2 2 2 0 Asparaginase Maf1 PF09174.10 OAJ17214.1 - 2.8 8.0 12.6 0.3 11.2 6.5 2.2 2 0 0 2 2 2 0 Maf1 regulator HemX PF04375.14 OAJ17214.1 - 3.1 7.0 23.8 5.6 6.2 23.8 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MGC-24 PF05283.11 OAJ17214.1 - 4.4 7.7 12.4 11 6.5 0.7 2.5 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Membralin PF09746.9 OAJ17214.1 - 7.8 5.4 11.8 0.74 8.8 5.6 1.9 2 0 0 2 2 2 0 Tumour-associated protein Gtr1_RagA PF04670.12 OAJ17215.1 - 7.4e-31 107.3 0.0 1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ17215.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ17215.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 OAJ17215.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OAJ17215.1 - 0.033 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OAJ17215.1 - 0.052 13.0 0.0 0.27 10.7 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ17215.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 OAJ17216.1 - 5.8e-10 38.8 0.0 0.00072 19.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cuticle_1 PF08140.11 OAJ17216.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Lactamase_B_2 PF12706.7 OAJ17217.1 - 5.5e-22 78.3 0.0 1.6e-15 57.2 0.0 3.4 3 0 0 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAJ17217.1 - 2.3e-06 27.6 0.0 5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GAPT PF11770.8 OAJ17218.1 - 0.018 14.9 0.1 0.097 12.5 0.0 2.1 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) DUF5527 PF17665.1 OAJ17218.1 - 0.038 13.5 0.2 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Roughex PF06020.11 OAJ17218.1 - 2 7.5 5.0 3.6 6.6 5.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein EphA2_TM PF14575.6 OAJ17243.1 - 0.16 12.8 0.0 2.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain tRNA-synt_1g PF09334.11 OAJ17246.1 - 1.4e-150 501.4 0.1 1.7e-150 501.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAJ17246.1 - 2e-07 29.7 0.6 3.5e-05 22.3 0.0 2.7 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.20 OAJ17246.1 - 3.3e-06 27.1 3.5 3.3e-06 27.1 3.5 2.2 1 1 1 2 2 2 1 WHEP-TRS domain DZR PF12773.7 OAJ17246.1 - 0.12 12.4 3.7 0.28 11.2 3.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAJ17246.1 - 0.45 10.7 2.1 6.1 7.0 0.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 OAJ17246.1 - 0.82 9.5 0.0 0.82 9.5 0.0 2.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OAJ17246.1 - 4.3 6.9 5.6 28 4.3 1.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Brix PF04427.18 OAJ17247.1 - 2e-21 77.0 0.0 2.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 OAJ17247.1 - 0.14 11.5 35.1 0.007 15.8 25.0 2.2 2 0 0 2 2 2 0 BUD22 FHA PF00498.26 OAJ17250.1 - 0.032 14.6 0.0 0.08 13.3 0.0 1.8 2 0 0 2 2 2 0 FHA domain MSA-2c PF12238.8 OAJ17250.1 - 0.69 9.9 3.3 0.99 9.4 3.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c PPR PF01535.20 OAJ17251.1 - 4.7e-07 29.6 0.0 0.27 11.6 0.0 4.4 4 0 0 4 4 4 3 PPR repeat PPR_2 PF13041.6 OAJ17251.1 - 0.00027 21.1 0.0 0.87 9.8 0.0 4.4 5 0 0 5 5 5 1 PPR repeat family PPR_1 PF12854.7 OAJ17251.1 - 0.0054 16.4 0.5 0.034 13.9 0.1 2.3 2 0 0 2 2 2 1 PPR repeat MscS_porin PF12795.7 OAJ17252.1 - 0.0016 18.0 0.9 0.0017 17.9 0.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Sugarporin_N PF11471.8 OAJ17252.1 - 0.0041 17.0 0.2 0.0071 16.3 0.2 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension eIF3m_C_helix PF18005.1 OAJ17252.1 - 0.078 12.7 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix UBX PF00789.20 OAJ17280.1 - 1.2e-06 28.6 0.0 4.5e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 OAJ17280.1 - 7.4e-05 22.6 0.0 0.00023 21.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DUF572 PF04502.13 OAJ17280.1 - 0.015 14.9 17.1 0.021 14.5 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2 PF00096.26 OAJ17280.1 - 0.044 14.3 0.1 0.072 13.6 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 OAJ17280.1 - 0.096 12.6 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Rtf2 PF04641.12 OAJ17280.1 - 0.13 11.6 21.0 0.21 10.9 21.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger GREB1 PF15782.5 OAJ17280.1 - 0.59 7.2 3.3 0.63 7.1 3.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 OAJ17280.1 - 1.7 8.6 23.0 2.6 8.1 23.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-C2H2_2 PF12756.7 OAJ17280.1 - 2.6 8.4 7.2 0.33 11.3 0.3 2.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SKN1 PF03935.15 OAJ17281.1 - 2.8e-175 583.5 2.8 3.2e-175 583.3 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aminotran_1_2 PF00155.21 OAJ17282.1 - 2.4e-40 138.9 0.0 4.3e-40 138.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ17282.1 - 0.00014 20.5 0.0 0.00035 19.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fasciclin PF02469.22 OAJ17283.1 - 8.9e-39 132.6 0.0 5e-08 33.2 0.0 6.5 5 2 0 5 5 5 5 Fasciclin domain DUF4381 PF14316.6 OAJ17283.1 - 0.22 11.7 1.5 0.6 10.3 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) E1-E2_ATPase PF00122.20 OAJ17284.1 - 7.6e-39 133.1 13.8 4.1e-30 104.7 0.0 3.5 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ17284.1 - 3.1e-30 105.2 2.8 3.1e-30 105.2 2.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ17284.1 - 2.2e-21 77.1 0.0 1.3e-19 71.3 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ17284.1 - 5.2e-20 71.3 0.1 1.2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ17284.1 - 8.3e-15 54.2 0.0 8.3e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ17284.1 - 1.7e-07 31.3 0.1 9.2e-06 25.6 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP19 PF01922.17 OAJ17284.1 - 0.073 14.0 0.0 0.75 10.8 0.0 2.5 2 0 0 2 2 2 0 SRP19 protein Tyr_Deacylase PF02580.16 OAJ17285.1 - 1.8e-52 177.7 0.0 2.2e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sec16_C PF12931.7 OAJ17286.1 - 1e-91 307.8 0.0 1.4e-91 307.3 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAJ17286.1 - 2.1e-19 70.3 0.1 6.9e-19 68.6 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region BAR_2 PF10455.9 OAJ17287.1 - 1.4e-41 142.5 0.0 4.3e-41 140.9 0.0 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAJ17287.1 - 6.5e-12 45.6 1.1 3.2e-09 36.8 0.2 2.1 2 0 0 2 2 2 2 BAR domain HAUS2 PF15003.6 OAJ17287.1 - 0.066 12.9 0.8 0.17 11.6 0.8 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Seryl_tRNA_N PF02403.22 OAJ17287.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1090 PF06476.12 OAJ17287.1 - 1.7 8.8 9.0 0.1 12.7 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF4112 PF13430.6 OAJ17288.1 - 2.4e-31 108.1 0.1 3.2e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF3983 PF13137.6 OAJ17288.1 - 0.19 11.6 2.0 7.7 6.4 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3983) Asp PF00026.23 OAJ17315.1 - 2.2e-07 30.6 0.0 2.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OAJ17315.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3432 PF11914.8 OAJ17316.1 - 0.77 10.0 18.2 1.3 9.3 18.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) F-box-like PF12937.7 OAJ17317.1 - 3.4e-14 52.4 4.1 9.5e-14 51.0 0.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 OAJ17317.1 - 2.8e-10 39.8 3.3 4.9e-10 39.0 0.1 2.6 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 OAJ17317.1 - 0.0042 16.9 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 F-box RXT2_N PF08595.11 OAJ17317.1 - 0.84 9.6 5.5 12 5.9 0.0 2.1 1 1 1 2 2 2 0 RXT2-like, N-terminal CPBP PF02517.16 OAJ17318.1 - 1.2e-17 64.0 4.7 1.2e-17 64.0 4.7 2.5 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease PCI PF01399.27 OAJ17319.1 - 2.6e-07 31.1 0.1 7.2e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 OAJ17319.1 - 0.13 12.4 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1180 PF06679.12 OAJ17319.1 - 9.5 6.6 9.2 21 5.5 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) START PF01852.19 OAJ17320.1 - 0.00091 18.7 0.1 0.002 17.6 0.1 1.5 1 0 0 1 1 1 1 START domain RPA43_OB PF17875.1 OAJ17320.1 - 0.0048 17.5 0.1 2.4 8.8 0.0 2.9 2 0 0 2 2 2 2 RPA43 OB domain in RNA Pol I BSP_II PF05432.11 OAJ17320.1 - 1.9 8.1 8.6 2.5 7.7 3.1 2.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) F-box-like PF12937.7 OAJ17321.1 - 3.5e-05 23.6 0.2 0.00026 20.8 0.2 2.2 1 1 0 1 1 1 1 F-box-like CENP-B_dimeris PF09026.10 OAJ17321.1 - 0.058 13.8 0.7 0.16 12.4 0.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PALP PF00291.25 OAJ17322.1 - 4.8e-48 164.1 0.4 1.7e-45 155.7 0.4 2.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LapA_dom PF06305.11 OAJ17322.1 - 0.04 13.7 0.3 0.04 13.7 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ADH_zinc_N PF00107.26 OAJ17322.1 - 0.041 13.9 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ribonuclease_3 PF00636.26 OAJ17323.1 - 1.1e-36 125.6 0.0 2.1e-18 66.9 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ17323.1 - 2.2e-20 73.1 5.4 6.1e-12 45.8 0.3 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 OAJ17323.1 - 4.9e-17 62.3 0.0 1.4e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 OAJ17323.1 - 3.1e-16 59.3 0.1 3.5e-15 55.9 0.2 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 OAJ17323.1 - 2.4e-08 34.0 0.0 6.6e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ17323.1 - 2.2e-07 31.1 0.0 1.1e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.26 OAJ17323.1 - 0.0064 17.2 0.0 0.058 14.1 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif p450 PF00067.22 OAJ17324.1 - 2.5e-35 122.1 0.0 2.1e-17 63.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Inositol_P PF00459.25 OAJ17325.1 - 9.6e-61 205.7 0.0 1.2e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cytomega_UL84 PF06284.11 OAJ17348.1 - 0.064 11.7 2.1 0.1 11.1 2.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 OAJ17348.1 - 0.14 12.5 3.9 0.31 11.5 3.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAJ17348.1 - 4.1 5.4 5.5 5.7 4.9 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi HTH_23 PF13384.6 OAJ17349.1 - 0.0029 17.3 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OAJ17349.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Rubredoxin PF00301.20 OAJ17350.1 - 0.016 15.3 0.1 0.061 13.4 0.1 2.1 1 0 0 1 1 1 0 Rubredoxin RGS12_us2 PF16611.5 OAJ17350.1 - 0.9 10.0 10.8 2.2 8.8 4.2 2.5 2 0 0 2 2 2 0 Unstructured region between RBD and GoLoco Amino_oxidase PF01593.24 OAJ17351.1 - 7.1e-60 203.6 0.1 9.2e-60 203.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ17351.1 - 1.3e-08 34.9 3.7 9.3e-08 32.2 3.7 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ17351.1 - 8.2e-06 25.6 5.9 0.00013 21.7 5.9 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ17351.1 - 0.00047 19.5 0.1 0.018 14.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ17351.1 - 0.011 14.9 1.8 0.028 13.5 1.8 1.7 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAJ17351.1 - 0.028 13.6 0.7 0.084 12.1 0.5 1.8 1 1 1 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAJ17351.1 - 0.031 14.8 0.1 12 6.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ17351.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAJ17351.1 - 0.18 11.8 0.1 0.86 9.6 0.1 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 OAJ17353.1 - 4.5e-33 114.6 37.3 7.4e-33 113.9 37.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAJ17353.1 - 0.0028 16.0 1.1 0.0028 16.0 1.1 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_32N PF00251.20 OAJ17354.1 - 3.9e-22 79.2 0.0 9.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ17354.1 - 9.3e-14 51.7 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 OAJ17354.1 - 0.15 12.2 1.9 1.6 9.0 0.1 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Utp11 PF03998.13 OAJ17355.1 - 1.7e-54 185.4 12.4 2e-54 185.1 12.4 1.1 1 0 0 1 1 1 1 Utp11 protein Syntaxin_2 PF14523.6 OAJ17355.1 - 0.12 12.8 2.0 1 9.8 0.0 2.7 3 0 0 3 3 3 0 Syntaxin-like protein SLATT_5 PF18160.1 OAJ17355.1 - 0.13 11.6 0.7 0.23 10.8 0.4 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Acyl-thio_N PF12590.8 OAJ17355.1 - 0.4 11.2 2.1 3.8 8.1 0.4 2.2 1 1 1 2 2 2 0 Acyl-ATP thioesterase ABC1 PF03109.16 OAJ17356.1 - 6.7e-21 74.7 0.0 3.2e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family Pkinase PF00069.25 OAJ17357.1 - 1.7e-17 63.7 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17357.1 - 3.4e-12 46.2 0.0 9.5e-12 44.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OAJ17357.1 - 0.46 10.9 1.7 5.7 7.5 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat Peptidase_S9 PF00326.21 OAJ17358.1 - 9e-33 113.5 0.0 2.2e-32 112.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAJ17358.1 - 1.1e-05 25.1 0.0 8.8e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAJ17358.1 - 2.7e-05 23.5 0.1 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 OAJ17358.1 - 9.4e-05 22.4 0.0 0.00025 21.0 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 OAJ17358.1 - 0.0015 17.3 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 OAJ17358.1 - 0.0047 16.6 0.6 0.21 11.2 0.3 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17358.1 - 0.011 16.4 0.8 0.011 16.4 0.8 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAJ17358.1 - 0.016 15.1 0.1 0.11 12.3 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 OAJ17384.1 - 1.1e-40 139.8 0.0 1.6e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ17384.1 - 2.3e-12 47.3 0.2 2.9e-08 34.2 0.1 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 OAJ17384.1 - 2.8e-08 33.0 3.1 0.00013 21.6 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ17384.1 - 4.2e-08 32.2 4.0 8e-05 21.9 1.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAJ17384.1 - 5.4e-08 33.2 0.2 0.002 18.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ17384.1 - 1.8e-05 24.0 2.8 0.0042 16.5 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OAJ17384.1 - 0.0018 18.1 2.9 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair NAD_binding_7 PF13241.6 OAJ17384.1 - 0.015 15.7 0.5 4.3 7.8 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ17384.1 - 0.028 13.7 5.4 0.29 10.3 3.8 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SPARC_Ca_bdg PF10591.9 OAJ17384.1 - 0.23 11.8 1.5 6.4 7.1 0.2 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CAP_N PF01213.19 OAJ17384.1 - 1.8 8.0 5.5 3.1 7.2 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 OAJ17384.1 - 4.3 7.4 5.2 9.4 6.3 5.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 P21-Arc PF04062.14 OAJ17385.1 - 1.7e-78 262.6 0.0 1.9e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit vATP-synt_E PF01991.18 OAJ17386.1 - 1.8e-60 203.8 14.2 2.1e-60 203.6 14.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 OAJ17386.1 - 3.2 7.6 6.1 1.8 8.4 3.5 1.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport zf-RING_2 PF13639.6 OAJ17388.1 - 2.1e-12 47.2 4.3 4.8e-12 46.0 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAJ17388.1 - 1.4e-10 40.7 2.1 1.4e-10 40.7 2.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ17388.1 - 1.3e-06 28.1 3.7 2.5e-06 27.2 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 OAJ17388.1 - 2.4e-05 24.3 0.1 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 1 PA domain zf-C3HC4 PF00097.25 OAJ17388.1 - 3e-05 23.8 1.7 6.1e-05 22.8 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ17388.1 - 3e-05 23.9 2.0 5.6e-05 23.0 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ17388.1 - 0.00038 20.4 0.3 0.00038 20.4 0.3 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAJ17388.1 - 0.00064 20.0 4.7 0.0025 18.1 4.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAJ17388.1 - 0.0012 18.7 5.4 0.0027 17.5 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ17388.1 - 0.038 14.0 1.9 0.1 12.7 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 OAJ17388.1 - 0.099 12.9 1.3 0.2 11.9 1.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family Baculo_RING PF05883.11 OAJ17388.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.6 OAJ17388.1 - 0.44 10.4 5.6 1 9.2 5.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 OAJ17388.1 - 2.8 8.2 4.5 12 6.2 4.4 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain PBP1_TM PF14812.6 OAJ17388.1 - 6.1 7.3 16.0 0.031 14.6 2.2 3.8 5 0 0 5 5 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP2C PF00481.21 OAJ17389.1 - 7.9e-29 101.1 0.0 1.4e-27 97.0 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.7 OAJ17391.1 - 1.4e-08 34.9 0.8 0.76 10.3 0.1 5.9 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAJ17391.1 - 3.5e-05 23.6 2.9 3.5e-05 23.6 2.9 2.5 3 0 0 3 3 3 1 F-box-like CRAL_TRIO PF00650.20 OAJ17392.1 - 8.1e-36 123.1 0.1 1.3e-35 122.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ17392.1 - 1.1e-11 44.8 0.2 1.1e-11 44.8 0.2 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain Ras PF00071.22 OAJ17420.1 - 6.6e-54 181.9 0.0 7.5e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ17420.1 - 3e-21 75.8 0.0 4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17420.1 - 6.9e-06 25.6 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ17420.1 - 0.0031 17.1 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ribo_biogen_C PF04034.13 OAJ17421.1 - 6e-47 158.5 0.0 8.8e-47 158.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAJ17421.1 - 6.8e-14 51.4 0.1 1.3e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.12 OAJ17421.1 - 4.2 6.7 22.8 1.2 8.4 15.5 2.1 2 0 0 2 2 2 0 SDA1 TFIIA PF03153.13 OAJ17421.1 - 6.5 6.6 21.6 23 4.8 17.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SURF2 PF05477.11 OAJ17421.1 - 8.9 5.9 13.1 9.6 5.8 8.2 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) ICL PF00463.21 OAJ17422.1 - 3.5e-264 877.2 1.5 4e-264 877.0 1.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAJ17422.1 - 2.6e-09 36.9 0.0 4.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 OAJ17422.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Rhomboid_N PF12122.8 OAJ17422.1 - 0.12 12.6 0.0 20 5.4 0.0 2.9 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Mad3_BUB1_I PF08311.12 OAJ17423.1 - 2.4e-36 124.5 0.2 3.8e-36 123.8 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OAJ17423.1 - 1.7e-06 27.6 0.0 3.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain DUF4632 PF15451.6 OAJ17423.1 - 0.14 12.2 1.1 0.96 9.6 1.1 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Pkinase_Tyr PF07714.17 OAJ17423.1 - 0.19 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Translin PF01997.16 OAJ17424.1 - 4.9e-44 150.8 0.1 6e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.9 OAJ17424.1 - 0.027 14.8 0.1 0.58 10.5 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EST1_DNA_bind PF10373.9 OAJ17425.1 - 4.5e-31 108.4 0.0 7.9e-24 84.6 0.0 3.2 2 1 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 OAJ17425.1 - 9.4e-17 61.9 0.0 4e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 Secretin_N_2 PF07655.13 OAJ17425.1 - 0.027 15.0 0.2 0.027 15.0 0.2 3.8 4 0 0 4 4 4 0 Secretin N-terminal domain CDP-OH_P_transf PF01066.21 OAJ17426.1 - 2.9e-13 50.4 0.4 8.5e-13 48.9 0.4 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase NAD_binding_11 PF14833.6 OAJ17427.1 - 2.9e-29 101.8 0.1 5.8e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAJ17427.1 - 3.9e-29 101.9 0.0 8.1e-29 100.8 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ntox10 PF15520.6 OAJ17427.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Novel toxin 10 Tubulin_2 PF13809.6 OAJ17427.1 - 0.089 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Tubulin like LcrG PF07216.12 OAJ17427.1 - 0.17 11.8 0.0 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 LcrG protein Cellulase PF00150.18 OAJ17429.1 - 8e-18 64.9 5.1 2.4e-17 63.3 5.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1554 PF07588.11 OAJ17429.1 - 1.4 8.7 5.8 0.18 11.6 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1554) Reprolysin_2 PF13574.6 OAJ17455.1 - 8.2 6.3 7.7 29 4.5 0.1 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Acyltransferase PF01553.21 OAJ17456.1 - 5.1e-17 61.8 0.1 8e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Peptidase_M20 PF01546.28 OAJ17457.1 - 8.3e-18 64.8 3.3 5.7e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 OAJ17457.1 - 5.2e-11 42.9 14.4 0.00034 21.3 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat M20_dimer PF07687.14 OAJ17457.1 - 2.5e-08 33.8 0.0 6.6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 OAJ17457.1 - 0.00025 21.3 0.2 0.27 11.6 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BSP_II PF05432.11 OAJ17457.1 - 1.2 8.7 5.7 2.6 7.7 5.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.9 OAJ17457.1 - 1.4 7.4 4.3 2.2 6.7 4.3 1.2 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 OAJ17458.1 - 2.7e-59 200.7 4.5 3.8e-59 200.2 4.5 1.2 1 0 0 1 1 1 1 VIT family GAS2 PF02187.17 OAJ17459.1 - 0.019 15.0 0.3 0.052 13.6 0.3 1.7 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain KAR9 PF08580.10 OAJ17459.1 - 0.32 9.5 81.5 0.0066 15.1 53.2 5.8 2 1 1 3 3 3 0 Yeast cortical protein KAR9 IF4E PF01652.18 OAJ17461.1 - 3.9e-44 150.2 0.0 7.6e-44 149.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cation_efflux PF01545.21 OAJ17461.1 - 9.3e-40 136.5 7.5 7.9e-39 133.5 7.5 2.0 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ17461.1 - 2.3e-07 30.8 0.3 8.3e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter SPX PF03105.19 OAJ17461.1 - 1.3 8.9 8.2 2.1 8.2 0.9 2.3 2 0 0 2 2 2 0 SPX domain LEA_2 PF03168.13 OAJ17462.1 - 0.11 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein T2SSF PF00482.23 OAJ17462.1 - 1.2 9.1 3.1 0.56 10.2 0.3 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Glyco_hydro_5_C PF18564.1 OAJ17463.1 - 6.2e-11 42.7 0.0 1.3e-08 35.2 0.0 2.8 3 0 0 3 3 3 2 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAJ17463.1 - 6.8e-09 35.6 0.0 9.4e-08 31.8 0.1 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) ATP-synt_D PF01813.17 OAJ17492.1 - 0.081 12.7 0.2 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 ATP synthase subunit D RRN3 PF05327.11 OAJ17492.1 - 0.16 10.5 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_UL69 PF05459.12 OAJ17494.1 - 0.017 14.5 0.5 0.021 14.2 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family ROF PF07073.12 OAJ17494.1 - 0.043 14.0 0.7 0.099 12.8 0.7 1.6 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) MFS_1 PF07690.16 OAJ17495.1 - 6.5e-42 143.7 49.8 6.5e-42 143.7 49.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ17495.1 - 2.9e-15 55.7 20.6 3.6e-15 55.4 20.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ17495.1 - 1.2e-11 44.2 10.3 1.2e-11 44.2 10.3 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter MRAP PF15183.6 OAJ17495.1 - 0.48 10.4 0.1 0.48 10.4 0.1 2.4 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family HCV_NS4a PF01006.20 OAJ17495.1 - 2.6 7.9 5.7 1.3 8.8 1.7 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a DUF3930 PF13067.6 OAJ17495.1 - 4.6 7.6 5.2 1.7 8.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) PS_Dcarbxylase PF02666.15 OAJ17496.1 - 1.3e-50 171.8 0.0 2.2e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAJ17496.1 - 5.6e-32 110.1 0.0 5.9e-17 61.8 0.0 4.0 3 1 0 3 3 3 3 C2 domain EF-hand_6 PF13405.6 OAJ17496.1 - 0.059 13.3 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain CNDH2_C PF16858.5 OAJ17496.1 - 0.19 11.6 4.2 0.4 10.5 0.4 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BNIP2 PF12496.8 OAJ17496.1 - 0.26 11.7 14.0 0.4 11.1 7.8 2.8 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC45 PF02724.14 OAJ17496.1 - 0.62 8.3 13.2 0.037 12.3 6.5 1.9 2 0 0 2 2 2 0 CDC45-like protein RVT_2 PF07727.14 OAJ17498.1 - 1.5e-60 204.8 0.0 2.1e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ17498.1 - 1.8e-20 73.3 0.2 8.9e-20 71.1 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ17498.1 - 9.4e-07 28.6 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ17498.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ17499.1 - 4.5e-12 45.8 0.1 7.5e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OAJ17499.1 - 1.3e-08 35.0 0.0 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ17499.1 - 0.24 11.5 3.1 0.46 10.6 3.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ17499.1 - 4.6 7.2 4.4 8.7 6.3 4.4 1.3 1 0 0 1 1 1 0 Zinc knuckle SpoIIE PF07228.12 OAJ17530.1 - 1.3e-07 31.7 0.0 0.033 14.1 0.0 3.3 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OAJ17530.1 - 9.1e-06 25.5 0.8 0.013 15.2 0.2 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.21 OAJ17530.1 - 5.9e-05 22.8 0.0 0.00069 19.3 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C zf-CCHC_3 PF13917.6 OAJ17532.1 - 0.0017 18.3 1.2 0.0032 17.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ17532.1 - 0.0034 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ17532.1 - 0.0037 17.3 4.5 0.0063 16.5 4.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ17532.1 - 0.011 15.5 7.9 0.02 14.7 7.9 1.3 1 0 0 1 1 1 0 Zinc knuckle VbhA PF18495.1 OAJ17532.1 - 0.25 11.3 1.1 5.6 6.9 0.0 3.1 3 0 0 3 3 3 0 Antitoxin VbhA zf-CCHC_5 PF14787.6 OAJ17532.1 - 0.26 11.0 8.5 0.071 12.8 4.9 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.14 OAJ17533.1 - 9.8e-73 244.8 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ17533.1 - 1.7e-19 70.2 0.0 4.5e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ17533.1 - 5.8e-06 26.0 0.1 1.7e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ17533.1 - 6.1e-05 22.8 0.5 0.00014 21.7 0.5 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_3 PF13358.6 OAJ17533.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease TPR_1 PF00515.28 OAJ17534.1 - 1e-29 101.1 20.9 2.5e-06 27.0 1.1 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17534.1 - 1.1e-29 100.1 22.5 3.1e-05 23.7 0.0 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ17534.1 - 3.2e-22 77.2 11.5 1.9e-05 24.7 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ17534.1 - 3.3e-22 78.9 14.0 7.5e-07 29.7 0.0 6.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ17534.1 - 1.8e-21 74.5 18.8 1.5e-05 24.8 0.1 8.8 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ17534.1 - 1.4e-17 63.7 17.8 9.5e-05 22.6 0.0 7.9 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ17534.1 - 5.8e-17 61.1 21.9 4.3e-07 29.5 0.0 7.8 5 2 3 8 8 7 5 TPR repeat TPR_14 PF13428.6 OAJ17534.1 - 8.3e-14 51.1 16.2 3.1e-05 24.4 0.0 8.8 2 2 8 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ17534.1 - 2.3e-13 50.4 21.8 7.2e-05 23.2 1.0 6.5 4 2 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ17534.1 - 5.4e-12 45.7 7.3 1.6e-05 25.0 0.1 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ17534.1 - 1.4e-10 41.2 12.1 0.00055 20.1 0.1 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAJ17534.1 - 5.7e-08 32.3 15.7 0.37 10.9 0.1 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ17534.1 - 1.7e-05 24.4 1.2 0.00015 21.3 0.1 2.9 3 1 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 OAJ17534.1 - 0.00015 22.0 10.5 0.057 13.8 0.0 5.3 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ17534.1 - 0.00053 19.3 10.6 0.073 12.3 1.7 4.2 2 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ17534.1 - 0.0028 17.5 18.4 12 5.9 0.0 8.2 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ17534.1 - 0.021 14.9 10.9 0.15 12.1 0.0 5.0 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 OAJ17534.1 - 0.021 15.4 1.3 23 6.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 OAJ17534.1 - 0.058 13.5 0.2 1.4 9.1 0.0 3.1 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPR_3 PF07720.12 OAJ17534.1 - 6.4 6.9 7.1 3.4 7.7 0.6 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Methyltransf_2 PF00891.18 OAJ17535.1 - 8.4e-24 84.0 0.0 2.7e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 OAJ17535.1 - 0.022 15.5 0.0 0.052 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_1b PF00579.25 OAJ17536.1 - 1.2e-59 202.1 0.0 3.2e-59 200.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 OAJ17536.1 - 0.15 10.9 0.0 5 5.9 0.0 2.3 2 1 0 2 2 2 0 tRNA synthetases class I (K) MSP1_C PF07462.11 OAJ17536.1 - 2.3 6.8 6.3 4.3 5.9 6.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rad60-SLD PF11976.8 OAJ17537.1 - 2.8e-22 78.3 0.2 3.3e-22 78.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ17537.1 - 6e-12 45.1 0.0 6.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family GTP_EFTU PF00009.27 OAJ17538.1 - 1.4e-56 191.2 0.1 2.4e-56 190.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAJ17538.1 - 3.4e-37 126.9 0.2 1.1e-36 125.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 OAJ17538.1 - 2.6e-29 101.1 0.0 5.9e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAJ17538.1 - 1.3e-22 79.6 0.2 3.2e-22 78.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ17538.1 - 5.4e-12 45.9 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAJ17538.1 - 1e-06 28.6 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain PPR_2 PF13041.6 OAJ17539.1 - 1.6e-27 95.4 0.1 1e-07 32.0 0.0 8.0 6 2 3 9 9 9 6 PPR repeat family PPR PF01535.20 OAJ17539.1 - 6.3e-20 70.0 4.0 0.014 15.6 0.0 9.2 12 1 0 12 12 12 4 PPR repeat PPR_3 PF13812.6 OAJ17539.1 - 1.5e-16 60.2 0.0 1.5e-06 28.2 0.0 7.2 4 1 4 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAJ17539.1 - 1.3e-12 47.2 0.1 0.00031 20.4 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 OAJ17539.1 - 5.2e-09 35.8 0.0 7.1e-08 32.1 0.0 2.7 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OAJ17539.1 - 0.0004 21.0 10.8 4.5 8.3 0.0 7.6 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ17539.1 - 0.0025 17.7 0.0 2.6 8.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Borrelia_REV PF03978.13 OAJ17539.1 - 0.22 11.5 0.0 0.6 10.1 0.0 1.6 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein Retrotrans_gag PF03732.17 OAJ17569.1 - 9e-09 35.5 0.1 7.6e-08 32.5 0.1 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 OAJ17570.1 - 4.8e-31 107.2 0.1 8.5e-31 106.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ17570.1 - 5e-31 106.7 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ17570.1 - 3.1e-30 105.3 0.1 2e-28 99.4 0.0 3.1 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ17570.1 - 1.6e-16 60.6 0.1 4.3e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ17570.1 - 6.7e-16 58.1 0.0 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ17570.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1639 PF07797.14 OAJ17571.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) MFS_1 PF07690.16 OAJ17573.1 - 1.3e-36 126.2 22.3 9.7e-36 123.4 23.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ThrE PF06738.12 OAJ17573.1 - 0.0019 17.6 2.1 0.0019 17.6 2.1 2.5 2 1 0 2 2 2 1 Putative threonine/serine exporter LapA_dom PF06305.11 OAJ17573.1 - 0.39 10.6 0.0 0.39 10.6 0.0 3.3 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain Hydrolase_4 PF12146.8 OAJ17574.1 - 6.4e-45 153.3 0.8 4.9e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ17574.1 - 7.7e-10 38.8 0.3 1.9e-09 37.6 0.3 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17574.1 - 1.7e-08 35.4 0.0 2.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAJ17574.1 - 0.00015 21.5 1.6 0.025 14.2 0.1 3.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAJ17574.1 - 0.019 14.6 0.1 0.038 13.6 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Asp2 PF16929.5 OAJ17574.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter DUF2771 PF10969.8 OAJ17574.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) Hydrolase_4 PF12146.8 OAJ17575.1 - 1.6e-23 83.2 0.1 3.9e-23 82.0 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ17575.1 - 4.9e-08 33.9 0.4 8.1e-08 33.1 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ17575.1 - 5e-08 32.9 1.3 9.2e-08 32.0 1.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SH3_2 PF07653.17 OAJ17576.1 - 0.00033 20.3 0.0 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAJ17576.1 - 0.0013 18.2 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Ldh_1_N PF00056.23 OAJ17577.1 - 0.0021 18.2 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAJ17579.1 - 8.7e-42 143.3 26.3 8.7e-42 143.3 26.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Rdx PF10262.9 OAJ17580.1 - 8.5e-23 80.3 0.0 1.8e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Rdx family ACPS PF01648.20 OAJ17613.1 - 2.3e-09 37.4 0.0 7.4e-09 35.7 0.0 1.8 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Myc_N PF01056.18 OAJ17615.1 - 0.38 10.6 3.7 6.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region TFIIE-A_C PF11521.8 OAJ17615.1 - 0.84 10.0 12.9 0.25 11.7 0.4 2.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Mito_fiss_reg PF05308.11 OAJ17615.1 - 6.2 6.8 6.6 1.8 8.6 0.8 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator CitMHS PF03600.16 OAJ17617.1 - 1.3 8.2 6.3 3.2 6.9 6.3 1.6 1 1 0 1 1 1 0 Citrate transporter Q_salvage PF10343.9 OAJ17618.1 - 2.3e-10 40.5 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family START PF01852.19 OAJ17619.1 - 9.2e-05 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 START domain F-box-like PF12937.7 OAJ17621.1 - 0.0022 17.9 0.3 0.0049 16.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like Pyr_redox_2 PF07992.14 OAJ17622.1 - 1.4e-39 136.1 0.0 1.1e-25 90.5 0.0 3.3 4 0 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ17622.1 - 4.5e-13 49.6 0.1 9.5e-08 32.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ17622.1 - 0.0051 17.0 0.0 7.3 6.9 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAJ17622.1 - 0.0063 15.8 0.0 14 4.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAJ17622.1 - 0.0073 16.7 0.0 0.4 11.2 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.18 OAJ17622.1 - 0.01 16.1 0.0 5 7.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 OAJ17622.1 - 0.015 14.4 0.0 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAJ17622.1 - 0.037 13.1 0.2 1.6 7.7 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain Ins_P5_2-kin PF06090.12 OAJ17649.1 - 1.4e-64 218.7 0.0 1.7e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C2H2 PF00096.26 OAJ17649.1 - 1.6e-11 44.0 7.4 2.3e-05 24.6 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ17649.1 - 1.2e-05 25.7 6.6 0.04 14.8 2.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ17649.1 - 0.02 15.3 10.2 0.02 15.3 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain DUF3268 PF11672.8 OAJ17649.1 - 0.099 13.0 0.5 0.2 12.0 0.5 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2_11 PF16622.5 OAJ17649.1 - 0.36 10.6 3.1 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OAJ17649.1 - 0.63 10.0 3.9 14 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 OAJ17649.1 - 1.4 9.0 4.1 6.4 6.9 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Ketoacyl-synt_C PF02801.22 OAJ17650.1 - 0.05 13.6 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Glypican PF01153.19 OAJ17650.1 - 3.8 6.2 5.1 9.3 4.9 5.1 1.6 1 0 0 1 1 1 0 Glypican DUF3337 PF11816.8 OAJ17652.1 - 7.5e-34 117.1 0.0 1.3e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAJ17652.1 - 1.8e-20 72.9 22.2 1.3e-05 25.9 0.1 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17652.1 - 9.9e-06 25.8 0.0 0.019 15.3 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ17652.1 - 0.26 10.2 0.0 0.59 9.0 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pirin PF02678.16 OAJ17653.1 - 6e-28 97.0 0.9 9.3e-28 96.4 0.9 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 OAJ17653.1 - 1.7e-06 27.6 1.6 1.6e-05 24.5 0.5 2.4 2 0 0 2 2 2 1 Cupin domain Tubulin PF00091.25 OAJ17654.1 - 1.1e-71 241.2 0.0 3e-71 239.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ17654.1 - 3e-42 143.8 0.3 4.6e-42 143.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ17654.1 - 6.6e-07 29.7 0.1 1.8e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ17654.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ17654.1 - 0.0022 17.2 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Iwr1 PF08574.10 OAJ17683.1 - 0.0022 19.0 12.8 0.0022 19.0 12.8 3.8 2 1 1 3 3 3 1 Transcription factor Iwr1 Thioesterase PF00975.20 OAJ17684.1 - 8.6e-08 32.6 0.1 1.9e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF2235 PF09994.9 OAJ17685.1 - 2.6e-70 237.1 0.0 3.8e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TauD PF02668.16 OAJ17686.1 - 1.6e-27 97.0 0.0 2.7e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RRN3 PF05327.11 OAJ17687.1 - 0.55 8.7 4.9 1 7.9 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OAJ17687.1 - 1.6 6.8 13.9 3.4 5.8 13.9 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ17687.1 - 3.2 5.9 10.6 5.7 5.1 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OAJ17687.1 - 3.8 7.2 6.3 0.7 9.5 1.9 2.1 2 0 0 2 2 2 0 FAM176 family BTAD PF03704.17 OAJ17689.1 - 0.0019 18.6 1.9 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_2 PF07719.17 OAJ17689.1 - 0.016 15.2 2.1 1.4 9.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ17689.1 - 0.086 13.1 1.1 17 5.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ17689.1 - 0.27 11.6 5.2 19 5.7 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 OAJ17690.1 - 1.2e-07 31.8 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_4 PF01565.23 OAJ17691.1 - 9.2e-22 77.3 3.0 2.1e-21 76.1 3.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ17691.1 - 0.01 15.9 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like CENP-B_dimeris PF09026.10 OAJ17694.1 - 0.12 12.8 7.9 0.063 13.7 4.5 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3245 PF11595.8 OAJ17694.1 - 2.1 8.8 7.4 21 5.6 6.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) NOA36 PF06524.12 OAJ17694.1 - 4.7 6.4 8.3 0.85 8.9 4.7 1.5 2 0 0 2 2 2 0 NOA36 protein OPT PF03169.15 OAJ17724.1 - 2.4e-133 446.0 45.8 3.1e-130 435.7 39.5 2.5 1 1 1 2 2 2 2 OPT oligopeptide transporter protein SUR7 PF06687.12 OAJ17725.1 - 1.3e-14 54.4 6.9 1.8e-14 53.9 6.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 OAJ17725.1 - 8.3e-09 35.5 0.5 8.3e-09 35.5 0.5 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction V_ATPase_I PF01496.19 OAJ17725.1 - 0.00038 18.5 0.0 0.00091 17.3 0.0 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Phage_holin_3_6 PF07332.11 OAJ17725.1 - 0.013 15.6 15.3 1.5 8.9 12.1 3.1 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SPC25 PF06703.11 OAJ17725.1 - 0.063 13.1 0.4 0.1 12.4 0.4 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3357 PF11837.8 OAJ17725.1 - 0.83 10.1 4.9 1.5 9.3 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) SLATT_3 PF18184.1 OAJ17725.1 - 2 8.5 5.3 4.1 7.5 5.3 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 LptF_LptG PF03739.14 OAJ17725.1 - 4.7 5.9 12.1 0.096 11.5 5.2 1.7 1 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF2070 PF09843.9 OAJ17725.1 - 5 5.3 14.1 7.7 4.7 14.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UAA PF08449.11 OAJ17726.1 - 1.3e-39 136.2 6.6 1.1e-38 133.1 6.6 2.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAJ17726.1 - 6.2e-06 26.4 3.2 6.2e-06 26.4 3.2 4.7 5 1 0 5 5 5 1 EamA-like transporter family Nuc_sug_transp PF04142.15 OAJ17726.1 - 0.0015 17.7 1.6 0.56 9.3 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 OAJ17726.1 - 0.0021 17.5 4.9 0.27 10.6 0.6 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family CRT-like PF08627.10 OAJ17726.1 - 0.02 13.9 3.9 0.84 8.5 0.2 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like CbiG_N PF11760.8 OAJ17726.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.3 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal TMEM234 PF10639.9 OAJ17726.1 - 0.25 11.4 4.9 4.5 7.4 0.3 2.8 3 0 0 3 3 3 0 Putative transmembrane family 234 EthD PF07110.11 OAJ17727.1 - 0.00029 21.9 0.7 0.084 14.0 0.2 2.8 2 1 0 2 2 2 2 EthD domain UDPGP PF01704.18 OAJ17728.1 - 2.1e-202 672.2 0.2 2.4e-202 672.0 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase tRNA-synt_2d PF01409.20 OAJ17729.1 - 3.9e-43 147.7 0.2 1.3e-25 90.3 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAJ17729.1 - 4.7e-23 81.4 0.0 1.2e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GATase_7 PF13537.6 OAJ17730.1 - 1.2e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAJ17730.1 - 3.1e-08 33.9 0.0 3.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain RBD PF02196.15 OAJ17730.1 - 0.0095 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain DUF1400 PF07176.11 OAJ17730.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Adap_comp_sub PF00928.21 OAJ17731.1 - 3.6e-93 311.8 0.0 6.7e-93 310.9 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAJ17731.1 - 8.1e-08 32.3 0.1 1.4e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OAJ17731.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF883 PF05957.13 OAJ17732.1 - 0.049 14.2 0.4 0.049 14.2 0.4 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) RRM_1 PF00076.22 OAJ17733.1 - 4.3e-14 52.1 0.0 5.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18 PF17135.4 OAJ17734.1 - 8.8e-90 299.1 2.0 1.1e-89 298.9 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAJ17734.1 - 0.00082 20.1 0.0 0.002 18.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HTH_Tnp_Tc3_2 PF01498.18 OAJ17735.1 - 2.3e-16 59.8 2.8 6.6e-16 58.3 2.8 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 OAJ17735.1 - 4.2e-14 52.5 0.0 7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.6 OAJ17735.1 - 0.0049 16.6 1.1 0.59 9.9 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.6 OAJ17735.1 - 0.018 15.6 1.0 0.018 15.6 1.0 3.5 3 1 0 3 3 3 0 Homeodomain-like domain HTH_31 PF13560.6 OAJ17735.1 - 0.36 11.2 3.4 4.1 7.8 0.7 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain MBOAT_2 PF13813.6 OAJ17761.1 - 2.1e-05 24.7 1.8 0.0026 18.0 0.3 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family PGA2 PF07543.12 OAJ17761.1 - 0.009 16.0 4.8 0.014 15.3 4.8 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 MetJ PF01340.20 OAJ17762.1 - 0.094 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Torus PF16131.5 OAJ17764.1 - 1.4e-06 28.9 0.0 4.1e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 OAJ17764.1 - 6.3e-06 26.1 3.1 1.8e-05 24.6 3.1 1.9 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 OAJ17764.1 - 6.5e-06 25.9 0.0 4.6e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ17764.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAJ17764.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 FYVE PF01363.21 OAJ17764.1 - 0.012 15.8 1.5 0.015 15.4 0.2 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_3 PF15663.5 OAJ17764.1 - 0.013 15.8 0.1 0.037 14.2 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 OAJ17764.1 - 0.037 13.9 1.2 0.037 13.9 1.2 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAJ17764.1 - 3 8.4 5.6 0.94 10.0 2.3 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MA3 PF02847.17 OAJ17765.1 - 9.1e-30 102.9 2.4 1e-28 99.5 0.3 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 OAJ17765.1 - 1.3e-08 34.8 0.4 9.3e-08 32.0 0.0 2.5 2 1 0 2 2 2 1 MIF4G domain RXT2_N PF08595.11 OAJ17765.1 - 0.069 13.2 0.0 0.069 13.2 0.0 5.9 8 0 0 8 8 8 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 OAJ17765.1 - 6.5 4.7 21.5 1.9 6.5 16.4 2.3 2 0 0 2 2 2 0 DNA polymerase phi MFS_1 PF07690.16 OAJ17766.1 - 5.4e-08 32.2 22.0 5.4e-08 32.2 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.12 OAJ17766.1 - 1.1 9.4 7.2 8.2 6.5 0.8 3.5 2 1 0 3 3 3 0 Invasion gene expression up-regulator, SirB Pro_CA PF00484.19 OAJ17795.1 - 5.6e-37 127.4 0.0 8.1e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 OAJ17795.1 - 0.037 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2236 PF09995.9 OAJ17796.1 - 9e-32 111.1 1.2 2.4e-31 109.7 1.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Maf PF02545.14 OAJ17797.1 - 3.3e-46 157.2 0.0 3.8e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SOG2 PF10428.9 OAJ17798.1 - 0.42 9.7 9.3 0.51 9.5 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GATA PF00320.27 OAJ17799.1 - 0.0045 16.6 3.0 0.0045 16.6 3.0 2.8 3 0 0 3 3 3 1 GATA zinc finger FAM76 PF16046.5 OAJ17799.1 - 0.24 10.7 9.4 0.42 9.9 2.0 2.4 2 0 0 2 2 2 0 FAM76 protein DUF5310 PF17237.2 OAJ17800.1 - 8.5e-19 67.2 5.7 1e-18 66.9 5.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) ADH_zinc_N PF00107.26 OAJ17801.1 - 5.1e-09 36.2 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ17801.1 - 0.0079 16.1 0.0 0.093 12.6 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 OAJ17802.1 - 3.7e-10 40.6 0.1 5.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 OAJ17803.1 - 6.3e-47 159.5 0.0 5.4e-27 95.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ17803.1 - 2.1e-45 155.5 19.2 5.4e-24 85.3 11.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.6 OAJ17803.1 - 3.4e-11 44.0 1.5 5.1e-06 27.1 0.5 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OAJ17803.1 - 8.7e-09 35.1 6.4 0.0034 16.9 0.2 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ17803.1 - 2.6e-08 33.5 1.0 0.0033 17.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ17803.1 - 4.7e-08 33.2 2.7 0.023 14.5 0.3 4.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAJ17803.1 - 9e-07 28.9 0.2 0.02 14.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ17803.1 - 2.2e-06 27.8 0.7 0.0082 16.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 OAJ17803.1 - 3.3e-06 26.3 0.2 0.015 14.3 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ17803.1 - 8.2e-06 26.3 3.1 0.13 12.6 0.1 3.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 OAJ17803.1 - 8.7e-05 22.4 3.8 0.00095 19.0 0.3 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OAJ17803.1 - 9.2e-05 21.8 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OAJ17803.1 - 0.00021 21.6 0.1 2 8.7 0.0 3.3 4 0 0 4 4 3 2 AAA domain DUF87 PF01935.17 OAJ17803.1 - 0.00029 21.0 2.4 0.0019 18.3 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 OAJ17803.1 - 0.00038 20.2 0.2 5.5 6.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OAJ17803.1 - 0.0013 18.9 0.5 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 OAJ17803.1 - 0.0014 18.8 6.1 0.39 10.8 0.1 2.6 3 0 0 3 3 2 2 Dynamin family AAA_27 PF13514.6 OAJ17803.1 - 0.0016 18.0 0.1 0.0055 16.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAJ17803.1 - 0.0028 17.3 0.0 1.4 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ17803.1 - 0.0032 16.9 0.2 0.59 9.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 OAJ17803.1 - 0.014 14.2 0.2 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ABC_ATPase PF09818.9 OAJ17803.1 - 0.021 13.7 4.4 3.7 6.2 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_7 PF12775.7 OAJ17803.1 - 0.021 14.4 0.2 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 OAJ17803.1 - 0.048 13.9 0.1 12 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ17803.1 - 0.06 13.1 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAJ17803.1 - 0.073 13.0 2.0 11 5.9 0.3 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 OAJ17803.1 - 0.085 12.4 2.8 3.7 7.1 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OAJ17803.1 - 0.091 12.0 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 OAJ17803.1 - 0.097 13.1 0.2 30 5.0 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ17803.1 - 0.13 11.4 0.2 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 OAJ17803.1 - 0.13 11.9 0.1 16 5.1 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OAJ17803.1 - 0.15 12.5 0.3 32 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 OAJ17803.1 - 0.16 11.7 0.7 10 5.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OAJ17803.1 - 0.19 11.6 0.4 14 5.5 0.0 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 OAJ17803.1 - 0.23 10.6 0.1 11 5.1 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 OAJ17803.1 - 0.39 11.3 1.9 10 6.6 0.3 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OAJ17803.1 - 0.4 10.9 2.1 8 6.7 0.1 3.2 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase UDPGT PF00201.18 OAJ17804.1 - 8.2e-14 51.3 0.1 1.2e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.13 OAJ17804.1 - 0.09 13.1 0.1 4.6 7.7 0.1 2.5 1 1 0 1 1 1 0 GHMP kinases C terminal UDPGT PF00201.18 OAJ17805.1 - 3.3e-12 46.0 0.1 5.4e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 OAJ17806.1 - 7.7e-13 48.1 0.2 1.2e-12 47.5 0.2 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase TubC_N PF18563.1 OAJ17806.1 - 0.22 11.5 0.2 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 TubC N-terminal docking domain Ank_4 PF13637.6 OAJ17829.1 - 2.9e-11 43.6 0.7 2e-06 28.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ17829.1 - 2e-06 28.3 0.0 5.3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ17829.1 - 1e-05 25.5 0.1 0.00027 21.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAJ17829.1 - 2.3e-05 24.6 0.0 7.8e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAJ17829.1 - 0.00062 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Methyltransf_11 PF08241.12 OAJ17829.1 - 0.0027 18.3 0.0 0.0061 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ17829.1 - 0.0053 17.8 0.1 0.033 15.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ17829.1 - 0.0059 17.3 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TB2_DP1_HVA22 PF03134.19 OAJ17831.1 - 5.5e-07 29.4 0.2 2.4e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Myb_DNA-binding PF00249.31 OAJ17834.1 - 9.8e-11 41.7 1.1 9.8e-11 41.7 1.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ17834.1 - 2.4e-07 30.9 2.0 3.7e-07 30.3 0.9 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ17834.1 - 0.048 13.6 0.3 0.09 12.7 0.3 1.4 1 0 0 1 1 1 0 Myb DNA-binding like SOCS PF12610.8 OAJ17834.1 - 0.19 12.2 5.0 0.099 13.0 0.9 2.9 2 0 0 2 2 2 0 Suppressor of cytokine signalling JAKMIP_CC3 PF16034.5 OAJ17834.1 - 7.1 6.5 9.6 4.6 7.1 5.3 2.3 2 0 0 2 2 2 0 JAKMIP CC3 domain Dynactin_p22 PF07426.11 OAJ17835.1 - 6.3e-09 35.9 2.3 2.5e-07 30.7 0.3 2.8 2 1 0 2 2 2 2 Dynactin subunit p22 Pox_A_type_inc PF04508.12 OAJ17835.1 - 0.0016 18.2 1.1 0.87 9.5 0.2 2.6 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Lebercilin PF15619.6 OAJ17835.1 - 0.3 10.7 7.8 0.13 11.9 3.8 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease F-box-like PF12937.7 OAJ17836.1 - 0.07 13.0 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 F-box-like AAA PF00004.29 OAJ17837.1 - 7.9e-52 175.2 0.0 9.6e-39 132.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 OAJ17837.1 - 3.8e-09 36.2 0.3 6.5e-08 32.3 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 OAJ17837.1 - 8.3e-09 35.1 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ17837.1 - 3.8e-08 33.6 0.1 2.4e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAJ17837.1 - 2.4e-07 31.3 0.0 0.019 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ17837.1 - 4.1e-07 30.4 0.0 0.00014 22.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ17837.1 - 4.7e-07 29.7 0.1 0.023 14.4 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAJ17837.1 - 1.4e-06 27.8 0.1 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 OAJ17837.1 - 4.2e-06 27.3 0.0 0.033 14.7 0.0 3.1 2 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 OAJ17837.1 - 7.8e-06 25.9 0.0 0.0027 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ17837.1 - 8.9e-06 25.2 0.3 0.0077 15.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ17837.1 - 1.3e-05 25.4 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OAJ17837.1 - 7.8e-05 22.5 0.1 0.062 13.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 OAJ17837.1 - 0.00013 22.0 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAJ17837.1 - 0.00018 21.8 0.0 0.12 12.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 OAJ17837.1 - 0.00024 21.1 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 OAJ17837.1 - 0.0003 20.0 0.0 0.19 10.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OAJ17837.1 - 0.00035 20.9 0.0 0.83 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAJ17837.1 - 0.00046 20.0 0.2 0.051 13.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 OAJ17837.1 - 0.0014 19.1 0.4 0.045 14.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 OAJ17837.1 - 0.0016 17.8 0.4 0.013 14.8 0.1 2.2 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 OAJ17837.1 - 0.0024 17.4 1.6 0.031 13.8 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region KTI12 PF08433.10 OAJ17837.1 - 0.0024 17.4 0.1 0.79 9.1 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 OAJ17837.1 - 0.0026 17.5 0.0 0.96 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAJ17837.1 - 0.0047 16.8 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 OAJ17837.1 - 0.0055 16.6 0.1 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 OAJ17837.1 - 0.007 16.3 1.1 4.4 7.2 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_25 PF13481.6 OAJ17837.1 - 0.0083 15.7 0.1 2.9 7.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 OAJ17837.1 - 0.011 15.5 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ17837.1 - 0.018 14.5 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 OAJ17837.1 - 0.019 14.9 0.3 29 4.5 0.0 3.5 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea CDC48_N PF02359.18 OAJ17837.1 - 0.022 14.9 0.0 0.11 12.7 0.0 2.2 3 0 0 3 3 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_30 PF13604.6 OAJ17837.1 - 0.028 14.2 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 OAJ17837.1 - 0.041 14.1 0.3 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 OAJ17837.1 - 0.06 12.4 0.1 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 OAJ17837.1 - 0.098 12.0 0.4 2.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 OAJ17837.1 - 0.099 13.1 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ17837.1 - 0.1 11.8 0.2 9.1 5.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 OAJ17837.1 - 0.14 12.1 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ17837.1 - 0.27 11.6 2.3 1.4 9.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain Fungal_trans PF04082.18 OAJ17865.1 - 2.8e-08 33.1 0.0 6.7e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ17865.1 - 1.1e-07 31.9 6.2 1.8e-07 31.2 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsbQ PF05757.11 OAJ17865.1 - 1.9 8.2 12.6 0.46 10.2 1.6 3.1 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) Polysacc_deac_1 PF01522.21 OAJ17866.1 - 4.8e-12 45.9 0.0 9.2e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Brr6_like_C_C PF10104.9 OAJ17869.1 - 0.043 13.6 0.7 0.043 13.6 0.7 1.7 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain PetN PF03742.14 OAJ17869.1 - 0.085 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 PetN Radical_SAM PF04055.21 OAJ17869.1 - 0.19 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Zn_clus PF00172.18 OAJ17870.1 - 2.5e-07 30.7 8.2 4.6e-07 29.8 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ17870.1 - 3.4e-07 29.6 0.0 6.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.12 OAJ17870.1 - 1.2 9.7 9.5 2.5 8.6 9.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Sec20 PF03908.13 OAJ17871.1 - 4.7e-20 71.3 0.7 4.7e-20 71.3 0.7 1.9 2 0 0 2 2 2 1 Sec20 DUF4813 PF16072.5 OAJ17871.1 - 3.3 7.3 22.3 6.4 6.3 22.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) EHN PF06441.12 OAJ17872.1 - 3.4e-24 85.3 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ17872.1 - 3.2e-10 40.1 0.1 5.7e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17872.1 - 0.00041 21.0 5.6 0.00041 21.0 5.6 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DNA_ligase_A_N PF04675.14 OAJ17873.1 - 1.4e-08 35.2 0.0 1.9e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus Suppressor_APC PF11414.8 OAJ17897.1 - 0.2 11.7 1.9 0.59 10.2 1.9 1.8 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Glypican PF01153.19 OAJ17897.1 - 0.34 9.7 2.3 0.76 8.5 2.3 1.5 1 0 0 1 1 1 0 Glypican DUF4149 PF13664.6 OAJ17898.1 - 7.2e-20 71.2 3.7 7.2e-20 71.2 3.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Hva1_TUDOR PF11160.8 OAJ17899.1 - 2.6e-13 49.9 0.1 2.6e-13 49.9 0.1 3.1 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain GREB1 PF15782.5 OAJ17899.1 - 9.5 3.2 25.6 10 3.0 25.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CAP_GLY PF01302.25 OAJ17900.1 - 3.5e-19 68.6 0.1 8.1e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 OAJ17900.1 - 4.5e-06 26.3 6.8 0.019 14.7 0.5 4.9 3 2 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OAJ17900.1 - 0.0014 19.0 7.4 1.8 9.1 0.0 4.8 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) FRG1 PF06229.12 OAJ17901.1 - 4.5e-21 75.4 4.2 3.7e-08 33.3 0.1 3.3 3 0 0 3 3 3 3 FRG1-like domain Fascin PF06268.13 OAJ17901.1 - 2.8e-06 27.5 0.0 0.0023 18.1 0.0 2.5 2 0 0 2 2 2 2 Fascin domain DUF4126 PF13548.6 OAJ17901.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) SNARE_assoc PF09335.11 OAJ17902.1 - 1.1e-13 51.8 1.3 2.3e-13 50.7 1.3 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PUF PF00806.19 OAJ17903.1 - 1.2e-14 53.0 0.9 2.8e-07 29.8 0.0 4.8 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat DUF676 PF05057.14 OAJ17904.1 - 0.00019 21.0 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OAJ17904.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OAJ17904.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 OAJ17904.1 - 1.4 8.5 10.2 0.1 12.2 0.8 3.3 3 1 0 3 3 3 0 alpha/beta hydrolase fold Herpes_BLLF1 PF05109.13 OAJ17905.1 - 7.7 4.4 11.3 7.4 4.4 11.3 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DNase_NucA_NucB PF14040.6 OAJ17906.1 - 1.6e-25 89.7 2.1 2.1e-25 89.3 2.1 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB FGGY_N PF00370.21 OAJ17907.1 - 8.9e-73 244.9 0.1 1.3e-72 244.3 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OAJ17907.1 - 7.5e-68 228.2 2.6 2.7e-67 226.3 1.4 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Polyketide_cyc PF03364.20 OAJ17935.1 - 2.3e-22 79.6 0.1 5.3e-22 78.4 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAJ17935.1 - 0.00036 20.8 0.1 0.026 14.8 0.1 2.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PAP1 PF08601.10 OAJ17935.1 - 1.4 8.6 7.2 1.6 8.4 7.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pheromone PF08015.11 OAJ17935.1 - 1.8 9.7 10.9 0.32 12.0 6.2 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone BTB PF00651.31 OAJ17936.1 - 7.5e-06 26.2 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_L32p PF01783.23 OAJ17937.1 - 1.5e-14 54.0 6.7 3.7e-14 52.7 6.7 1.7 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 OAJ17937.1 - 0.011 15.6 1.2 0.022 14.7 1.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GcpE PF04551.14 OAJ17937.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 GcpE protein DUF1180 PF06679.12 OAJ17937.1 - 3.8 7.9 7.7 6.3 7.2 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Nkap_C PF06047.11 OAJ17938.1 - 2.4e-44 149.6 4.7 2.4e-44 149.6 4.7 1.9 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain Macoilin PF09726.9 OAJ17938.1 - 0.0015 17.2 12.0 0.002 16.8 12.0 1.3 1 0 0 1 1 1 1 Macoilin family ABC_ATPase PF09818.9 OAJ17939.1 - 4.5e-08 32.3 0.0 6.7e-08 31.7 0.0 1.2 1 1 0 1 1 1 1 Predicted ATPase of the ABC class FGase PF05013.12 OAJ17939.1 - 0.1 12.8 0.0 5.6 7.1 0.0 2.1 1 1 1 2 2 2 0 N-formylglutamate amidohydrolase EF-hand_6 PF13405.6 OAJ17940.1 - 4.9e-07 29.2 0.2 0.015 15.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OAJ17940.1 - 6.3e-07 29.8 0.3 2.1e-06 28.1 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAJ17940.1 - 1.4e-06 27.5 0.0 0.014 14.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OAJ17940.1 - 2.1e-05 23.7 0.2 0.13 11.8 0.0 2.8 2 0 0 2 2 2 2 EF hand OCRE PF17780.1 OAJ17940.1 - 0.051 13.6 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 OCRE domain SPARC_Ca_bdg PF10591.9 OAJ17940.1 - 0.31 11.4 4.7 3.1 8.1 0.0 3.7 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.32 OAJ17941.1 - 3.8e-36 122.5 15.6 7.4e-07 29.8 0.4 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17941.1 - 3.7e-09 36.7 1.2 1.6 9.1 0.0 6.4 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 OAJ17941.1 - 4.6e-05 23.0 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 OAJ17941.1 - 0.011 14.8 0.5 1 8.2 0.0 3.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ17941.1 - 0.015 14.0 0.3 1 8.0 0.1 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Caudo_TAP PF02413.17 OAJ17941.1 - 0.82 9.8 6.4 0.27 11.4 0.6 2.5 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK NOA36 PF06524.12 OAJ17941.1 - 2.2 7.5 4.6 4.8 6.4 4.6 1.5 1 0 0 1 1 1 0 NOA36 protein SUIM_assoc PF16619.5 OAJ17941.1 - 3.9 7.6 16.4 11 6.1 6.2 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FtsJ PF01728.19 OAJ17942.1 - 7.6e-54 182.5 0.0 3.1e-43 148.0 0.0 2.1 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 OAJ17942.1 - 0.00012 22.7 0.0 0.00055 20.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OAJ17942.1 - 0.0057 16.3 0.2 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 OAJ17942.1 - 0.0066 16.3 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ17942.1 - 0.0078 16.0 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ17942.1 - 0.17 11.2 0.0 0.55 9.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Mur_ligase_M PF08245.12 OAJ17943.1 - 0.0009 19.3 0.5 0.25 11.3 0.5 2.9 1 1 0 1 1 1 1 Mur ligase middle domain AAR2 PF05282.11 OAJ17944.1 - 1.4e-43 149.6 1.4 1.5e-43 149.5 0.4 1.5 1 1 1 2 2 2 1 AAR2 protein Sorting_nexin PF03700.13 OAJ17944.1 - 0.019 15.5 3.7 0.019 15.5 3.7 3.1 3 0 0 3 3 3 0 Sorting nexin, N-terminal domain BPA_C PF18040.1 OAJ17944.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 beta porphyranase A C-terminal MID_MedPIWI PF18296.1 OAJ17944.1 - 1.2 8.8 7.3 3.9 7.2 2.0 2.3 2 0 0 2 2 2 0 MID domain of medPIWI TFIIA PF03153.13 OAJ17944.1 - 1.8 8.5 13.3 0.17 11.9 2.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 OAJ17944.1 - 3.8 8.3 7.4 67 4.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 OAJ17945.1 - 3.2e-07 30.6 8.1 6.1e-07 29.7 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAJ17945.1 - 0.00072 19.8 5.6 0.0016 18.7 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ17945.1 - 0.0013 18.7 1.5 0.0031 17.5 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OAJ17945.1 - 0.0059 16.8 3.7 0.013 15.6 3.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 OAJ17945.1 - 0.014 15.3 8.4 0.024 14.5 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OAJ17945.1 - 0.021 14.9 6.1 0.05 13.7 6.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 OAJ17945.1 - 0.037 13.9 7.6 0.075 12.9 7.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 OAJ17945.1 - 0.06 13.3 2.8 0.26 11.2 3.5 1.7 2 0 0 2 2 1 0 Putative zinc-RING and/or ribbon Phage_lysis PF03245.13 OAJ17945.1 - 0.12 12.5 0.4 0.91 9.7 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF4611 PF15387.6 OAJ17945.1 - 0.27 11.5 5.5 0.92 9.8 5.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) C1_1 PF00130.22 OAJ17945.1 - 0.44 10.5 3.4 0.87 9.5 3.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 OAJ17945.1 - 0.94 9.8 5.1 1.8 9.0 5.1 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OAJ17945.1 - 1 9.0 3.7 2 8.1 3.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CENP-B_dimeris PF09026.10 OAJ17945.1 - 1.5 9.2 8.6 4.9 7.6 8.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PHD PF00628.29 OAJ17945.1 - 2.4 8.1 5.2 4.4 7.3 5.2 1.4 1 0 0 1 1 1 0 PHD-finger Cullin PF00888.22 OAJ17947.1 - 1.5e-139 466.5 0.0 2.8e-139 465.6 0.0 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ17947.1 - 2.5e-20 72.2 0.8 7.1e-20 70.8 0.8 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 OAJ17947.1 - 0.048 14.2 0.4 0.18 12.4 0.4 2.0 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal SEP PF08059.13 OAJ17971.1 - 3.8e-19 69.0 0.0 7.9e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OAJ17971.1 - 1.9e-13 50.4 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAJ17971.1 - 9.4e-10 38.2 1.7 1.7e-09 37.4 1.7 1.4 1 0 0 1 1 1 1 UBA-like domain ACC_central PF08326.12 OAJ17972.1 - 2.4e-194 647.7 0.0 3e-194 647.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAJ17972.1 - 2.6e-165 550.8 0.0 3.5e-165 550.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAJ17972.1 - 1.5e-52 178.1 0.0 3.3e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAJ17972.1 - 2e-28 99.1 0.1 6.4e-28 97.5 0.1 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ17972.1 - 7.4e-22 77.5 0.0 3e-20 72.3 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ17972.1 - 3.9e-15 55.4 0.2 7.7e-15 54.5 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ17972.1 - 2.2e-06 27.4 0.0 6.5e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 OAJ17972.1 - 0.0032 17.4 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Ubiq_cyt_C_chap PF03981.12 OAJ17973.1 - 5.5e-29 101.1 0.1 2.4e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone DUF1631 PF07793.11 OAJ17974.1 - 0.58 8.5 12.4 0.74 8.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Gpi16 PF04113.14 OAJ17975.1 - 6.5e-99 331.9 0.0 1.2e-48 166.0 0.0 3.9 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component Aminotran_1_2 PF00155.21 OAJ17976.1 - 3.6e-43 148.1 0.0 1.7e-42 145.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II zf-CCHC PF00098.23 OAJ17977.1 - 0.00093 19.2 3.5 0.0017 18.3 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ17977.1 - 0.35 10.7 4.4 0.75 9.7 4.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 OAJ17978.1 - 2.8e-09 36.6 0.0 7.9e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RTC_insert PF05189.13 OAJ17978.1 - 0.058 13.9 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain LAG1-DNAbind PF09271.11 OAJ18007.1 - 1e-30 107.4 1.6 4.9e-30 105.2 0.0 2.5 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 OAJ18007.1 - 6.5e-06 26.5 0.0 2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4616 PF15394.6 OAJ18007.1 - 0.1 11.5 1.4 0.2 10.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) UvrD-helicase PF00580.21 OAJ18008.1 - 3.4e-68 230.5 0.3 6.8e-68 229.5 0.3 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OAJ18008.1 - 3.9e-58 197.5 0.0 3.8e-28 98.9 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OAJ18008.1 - 6.9e-31 107.6 0.0 1.6e-30 106.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAJ18008.1 - 8e-11 41.6 0.1 3.2e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OAJ18008.1 - 1.3e-05 25.1 0.1 0.22 11.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OAJ18008.1 - 0.0011 18.4 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_12 PF13087.6 OAJ18008.1 - 0.14 11.7 0.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain WLM PF08325.10 OAJ18009.1 - 2.5e-48 164.7 1.7 3.3e-48 164.3 0.0 2.0 3 1 0 3 3 3 1 WLM domain zf-RanBP PF00641.18 OAJ18009.1 - 4.9e-06 25.7 3.2 8.1e-06 25.1 3.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 OAJ18009.1 - 0.11 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 PhdYeFM_antitox PF02604.19 OAJ18009.1 - 0.11 12.3 0.4 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Med8 PF10232.9 OAJ18010.1 - 0.012 15.3 0.0 0.2 11.2 0.0 2.6 1 1 2 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 APG6_N PF17675.1 OAJ18010.1 - 0.47 11.0 9.5 0.041 14.4 2.9 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region 4HBT PF03061.22 OAJ18011.1 - 1.6e-09 38.0 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAJ18011.1 - 0.041 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Ald_Xan_dh_C2 PF02738.18 OAJ18013.1 - 3.9e-185 616.5 0.0 5.4e-185 616.0 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OAJ18013.1 - 2e-30 105.4 0.0 4.9e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 OAJ18013.1 - 5.9e-28 97.7 0.0 1.2e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OAJ18013.1 - 2.9e-24 84.9 0.1 6.2e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OAJ18013.1 - 2.4e-20 72.6 1.0 1.4e-19 70.1 0.0 2.8 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OAJ18013.1 - 1.8e-06 27.8 0.1 2.2e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CRAL_TRIO PF00650.20 OAJ18050.1 - 2e-11 43.9 0.0 1e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain Bunya_NS-S PF01104.17 OAJ18050.1 - 0.2 11.5 0.9 0.43 10.4 0.9 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Peptidase_M43 PF05572.13 OAJ18051.1 - 2.1e-08 34.2 0.1 5e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ18051.1 - 0.081 13.4 1.4 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.25 OAJ18053.1 - 0.00038 19.9 0.0 0.57 9.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18053.1 - 0.034 13.4 0.0 8 5.7 0.0 2.5 2 1 0 2 2 2 0 Protein tyrosine kinase Trimer_CC PF08954.11 OAJ18054.1 - 0.02 14.4 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Trimerisation motif Oxidored_FMN PF00724.20 OAJ18055.1 - 3.1e-60 204.2 0.0 3.9e-56 190.8 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Nuc_deoxyrib_tr PF05014.15 OAJ18055.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Redoxin PF08534.10 OAJ18056.1 - 2.4e-32 111.7 0.0 2.7e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ18056.1 - 1.5e-07 31.4 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Cellulase PF00150.18 OAJ18057.1 - 9.5e-12 44.9 5.9 1.4e-11 44.4 5.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) rve PF00665.26 OAJ18058.1 - 9.3e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Trp_repressor PF01371.19 OAJ18058.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein WTX PF09422.10 OAJ18059.1 - 0.087 11.9 3.5 0.084 11.9 3.5 1.1 1 0 0 1 1 1 0 WTX protein Metal_resist PF13801.6 OAJ18059.1 - 0.41 10.8 7.2 0.68 10.1 7.2 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Pkinase PF00069.25 OAJ18060.1 - 9.1e-08 31.8 0.0 6.3e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18060.1 - 1.3e-05 24.6 0.0 0.11 11.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Chitin_synth_2 PF03142.15 OAJ18089.1 - 1.6e-281 934.5 0.1 2e-281 934.2 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 OAJ18089.1 - 6.5e-13 49.1 0.1 2.1e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ18089.1 - 6.7e-11 42.5 1.8 1.9e-10 41.0 1.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAJ18089.1 - 0.00075 19.0 0.1 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ18089.1 - 0.017 15.0 0.0 0.074 12.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 RT_RNaseH PF17917.1 OAJ18090.1 - 1.9e-12 47.4 0.0 2.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ18090.1 - 4.3e-07 29.9 0.1 9.1e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 OAJ18092.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein rhaM PF05336.13 OAJ18092.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 L-rhamnose mutarotase RVT_1 PF00078.27 OAJ18093.1 - 2.5e-22 79.5 0.0 4.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ18093.1 - 1.2e-15 57.4 0.0 2.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ18093.1 - 5.7e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ18093.1 - 0.00045 20.8 0.2 0.0018 18.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ18093.1 - 0.095 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 OAJ18096.1 - 1.8e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 OAJ18098.1 - 1.3e-17 64.0 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 OAJ18098.1 - 0.0058 15.7 0.0 0.0058 15.7 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain rve PF00665.26 OAJ18098.1 - 0.027 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.14 OAJ18126.1 - 1e-65 221.8 0.0 1.7e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAJ18126.1 - 1.3e-20 73.5 0.2 2.4e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ18126.1 - 4.6e-14 52.6 0.0 3.7e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ18126.1 - 4.3e-10 39.3 0.1 1.2e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ18126.1 - 5.4e-07 29.4 1.4 1.2e-06 28.3 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.6 OAJ18126.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Carboxyl_trans PF01039.22 OAJ18127.1 - 0.019 13.6 0.0 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain Cutinase PF01083.22 OAJ18128.1 - 2.4e-23 83.0 0.3 2.8e-23 82.8 0.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ18128.1 - 0.032 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain RLAN PF14401.6 OAJ18131.1 - 0.00063 19.4 0.1 0.00092 18.9 0.1 1.3 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain DUF4566 PF15130.6 OAJ18131.1 - 0.058 12.8 0.5 0.11 11.9 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4566) Retrotrans_gag PF03732.17 OAJ18133.1 - 0.0034 17.6 0.2 0.006 16.8 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein RNA_pol_I_A49 PF06870.12 OAJ18133.1 - 0.33 9.8 1.2 1.5 7.6 1.2 1.8 1 1 0 1 1 1 0 A49-like RNA polymerase I associated factor RVT_1 PF00078.27 OAJ18135.1 - 4.2e-26 91.8 0.0 7.2e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ18135.1 - 9.1e-19 67.4 0.1 1.6e-10 40.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ18135.1 - 6.5e-16 58.5 0.0 2.3e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18135.1 - 5.9e-15 55.1 0.1 1.5e-14 53.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ18135.1 - 6.3e-12 45.7 0.0 1.7e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ18135.1 - 9.1e-05 23.0 0.0 0.00029 21.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 OAJ18135.1 - 0.0045 17.2 0.2 0.01 16.1 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein dUTPase PF00692.19 OAJ18135.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 dUTPase gag-asp_proteas PF13975.6 OAJ18135.1 - 0.011 16.3 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_21 PF13276.6 OAJ18135.1 - 0.33 11.1 1.1 4.8 7.4 0.4 2.7 2 0 0 2 2 2 0 HTH-like domain RVT_1 PF00078.27 OAJ18136.1 - 5.9e-25 88.1 0.0 9.9e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ18136.1 - 1.7e-21 76.1 0.0 6.1e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18136.1 - 4.1e-14 52.4 0.0 1.1e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ18136.1 - 1.2e-11 44.8 0.0 3.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ18136.1 - 1.2e-10 41.6 0.0 3.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ18136.1 - 0.00033 21.2 0.0 0.001 19.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease CCDC53 PF10152.9 OAJ18136.1 - 0.027 14.9 0.4 0.11 12.9 0.4 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex dUTPase PF00692.19 OAJ18136.1 - 0.04 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 dUTPase gag-asp_proteas PF13975.6 OAJ18136.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease FHA PF00498.26 OAJ18167.1 - 0.00026 21.3 0.0 0.00076 19.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain ORC6 PF05460.13 OAJ18167.1 - 0.13 11.5 9.7 0.19 11.0 9.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) GFO_IDH_MocA_C PF02894.17 OAJ18167.1 - 0.2 11.6 0.4 2.3 8.3 0.2 2.1 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Spt5_N PF11942.8 OAJ18168.1 - 3.6e-20 72.8 10.3 3.6e-20 72.8 10.3 3.5 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 OAJ18168.1 - 6.9e-19 67.5 0.1 2e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OAJ18168.1 - 1.2e-07 31.4 21.6 0.0081 16.1 0.4 5.3 5 0 0 5 5 5 4 KOW motif DUF4537 PF15057.6 OAJ18168.1 - 0.005 16.8 0.9 13 5.9 0.3 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4537) Utp14 PF04615.13 OAJ18168.1 - 7.1 5.1 23.3 10 4.5 23.3 1.1 1 0 0 1 1 1 0 Utp14 protein OPT PF03169.15 OAJ18170.1 - 4.8e-142 474.7 33.6 6.3e-142 474.3 33.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HMG_box PF00505.19 OAJ18171.1 - 8.7e-08 32.5 0.6 1.9e-07 31.4 0.9 4.5 4 1 0 5 5 5 2 HMG (high mobility group) box DUF2461 PF09365.10 OAJ18172.1 - 5.3e-59 199.7 0.1 7.6e-59 199.2 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Pkinase PF00069.25 OAJ18173.1 - 8.1e-59 199.1 0.0 8.4e-35 120.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18173.1 - 2e-22 79.7 0.0 2.7e-20 72.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ18173.1 - 0.22 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Metallophos PF00149.28 OAJ18174.1 - 4e-36 125.4 0.1 6.4e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ18174.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 OAJ18174.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) WD40 PF00400.32 OAJ18175.1 - 0.0036 18.1 11.5 0.22 12.5 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat SPX PF03105.19 OAJ18175.1 - 0.41 10.5 12.4 2.1 8.2 0.2 2.8 2 1 0 2 2 2 0 SPX domain Ldh_1_N PF00056.23 OAJ18201.1 - 0.0021 18.2 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Methyltrn_RNA_2 PF04013.12 OAJ18203.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase GCR1_C PF12550.8 OAJ18204.1 - 5.2e-20 71.6 1.1 7.1e-20 71.1 1.1 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Dus PF01207.17 OAJ18205.1 - 1e-46 159.4 0.0 1.5e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Dppa2_A PF14049.6 OAJ18207.1 - 0.0024 17.9 0.5 0.074 13.2 0.0 2.2 2 0 0 2 2 2 1 Dppa2/4 conserved region in higher vertebrates SLT_2 PF13406.6 OAJ18207.1 - 0.07 12.4 0.5 0.097 11.9 0.5 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF4794 PF16042.5 OAJ18207.1 - 0.13 13.3 2.3 0.27 12.3 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4794) Nup192 PF11894.8 OAJ18208.1 - 1.7e-223 744.9 4.4 2.1e-223 744.6 4.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 OAJ18208.1 - 0.12 10.3 0.1 0.31 8.9 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin subcomplex protein binding to Pom34 F-box PF00646.33 OAJ18209.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ18209.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 OAJ18209.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like 4HBT_3 PF13622.6 OAJ18210.1 - 5.8e-56 190.5 0.0 1.1e-55 189.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ18210.1 - 1.2e-21 77.0 0.0 1.9e-18 66.6 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase RVT_1 PF00078.27 OAJ18211.1 - 2.5e-25 89.3 0.0 4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ18211.1 - 1.5e-21 76.3 0.0 1.3e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ18211.1 - 7.7e-15 55.1 0.0 3.7e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18211.1 - 1.1e-13 51.1 0.0 2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ18211.1 - 4.1e-12 46.3 0.0 1.3e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Serglycin PF04360.12 OAJ18238.1 - 0.16 11.9 1.0 0.29 11.1 1.0 1.4 1 0 0 1 1 1 0 Serglycin DUF3381 PF11861.8 OAJ18238.1 - 4.7 7.0 16.4 1.2 9.0 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) WD40 PF00400.32 OAJ18239.1 - 1e-15 57.8 8.8 0.0084 16.9 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAJ18239.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 GCIP PF13324.6 OAJ18239.1 - 1.6 8.3 8.7 2.8 7.5 8.7 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Vfa1 PF08432.10 OAJ18239.1 - 2.4 8.5 8.0 6.3 7.1 8.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 OAJ18239.1 - 6.2 5.0 12.3 9.5 4.4 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 OAJ18239.1 - 9.7 4.6 17.6 20 3.6 17.6 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.16 OAJ18240.1 - 4.5e-37 127.8 37.2 4.5e-37 127.8 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ18240.1 - 1.4e-09 37.4 5.5 1.4e-09 37.4 5.5 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter VWA_3 PF13768.6 OAJ18241.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 OAJ18241.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain T2SS-T3SS_pil_N PF13629.6 OAJ18241.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region Gram_pos_anchor PF00746.21 OAJ18241.1 - 0.35 10.8 3.6 0.74 9.8 0.6 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DEAD PF00270.29 OAJ18242.1 - 1.4e-22 80.3 0.0 1.8e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ18242.1 - 0.0083 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 OAJ18243.1 - 6.9e-19 68.6 0.0 4.7e-09 36.8 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAJ18243.1 - 1.8e-13 50.9 1.2 7.4e-13 48.9 1.2 2.0 1 1 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 OAJ18243.1 - 0.0013 19.1 0.7 0.0091 16.4 0.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OAJ18243.1 - 0.0064 16.3 0.1 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ18243.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ18243.1 - 0.033 14.5 0.1 0.37 11.1 0.0 2.6 1 1 1 2 2 2 0 AAA domain Pex14_N PF04695.13 OAJ18243.1 - 0.078 13.6 12.0 2.2 8.9 0.4 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM240 PF15207.6 OAJ18243.1 - 0.11 12.2 0.2 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 TMEM240 family ABC_tran PF00005.27 OAJ18243.1 - 0.14 12.7 0.1 2.8 8.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Trypan_PARP PF05887.11 OAJ18243.1 - 9.3 6.2 14.6 2.4 8.1 5.0 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Hist_deacetyl PF00850.19 OAJ18244.1 - 4.8e-38 131.4 0.0 9.2e-38 130.4 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain PIG-X PF08320.12 OAJ18245.1 - 1.5e-19 70.8 0.0 1.5e-10 41.4 0.0 2.9 2 1 0 2 2 2 2 PIG-X / PBN1 Med22 PF06179.12 OAJ18246.1 - 2e-14 53.7 0.2 3e-14 53.1 0.2 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Brix PF04427.18 OAJ18247.1 - 4.9e-34 118.1 0.0 6.7e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.12 OAJ18247.1 - 0.37 9.0 34.6 0.5 8.5 34.6 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 OAJ18247.1 - 1.7 8.0 25.6 2.8 7.3 25.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CNDH2_C PF16858.5 OAJ18247.1 - 2 8.2 10.3 3.6 7.4 10.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Paf1 PF03985.13 OAJ18247.1 - 2.2 7.2 15.9 3.8 6.4 15.9 1.3 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 OAJ18247.1 - 6.6 4.9 24.6 10 4.3 24.6 1.3 1 0 0 1 1 1 0 CDC45-like protein S1 PF00575.23 OAJ18280.1 - 8.3e-32 109.4 9.6 4.8e-07 30.0 0.8 8.4 8 0 0 8 8 8 5 S1 RNA binding domain Suf PF05843.14 OAJ18280.1 - 2e-09 37.9 1.3 5.8e-07 29.8 0.0 3.6 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 OAJ18280.1 - 2.9e-06 27.7 0.0 2.6 8.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat NRDE-2 PF08424.10 OAJ18280.1 - 7.4e-06 25.3 4.6 0.00021 20.5 1.7 2.9 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 OAJ18280.1 - 0.00026 21.5 2.4 0.0071 17.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18280.1 - 0.0004 21.0 1.9 9.6 7.3 0.0 5.8 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ18280.1 - 0.0019 17.5 2.7 0.0088 15.3 2.2 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF2110 PF09883.9 OAJ18280.1 - 0.0044 16.7 0.3 3.4 7.2 0.0 3.9 3 1 1 4 4 4 1 Uncharacterized protein conserved in archaea (DUF2110) TPR_6 PF13174.6 OAJ18280.1 - 0.043 14.5 0.8 2.4 9.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 OAJ18282.1 - 2.8e-16 59.8 0.7 4.7e-16 59.0 0.7 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sigma_M_inh PF17453.2 OAJ18282.1 - 0.19 12.2 0.9 0.43 11.1 0.9 1.5 1 0 0 1 1 1 0 Sigma-M inhibitor Ribosomal_L29 PF00831.23 OAJ18283.1 - 5.9e-19 67.8 3.5 5.9e-19 67.8 3.5 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein VirB8 PF04335.13 OAJ18283.1 - 0.026 14.4 0.2 0.028 14.3 0.2 1.1 1 0 0 1 1 1 0 VirB8 protein Peptidase_M18 PF02127.15 OAJ18284.1 - 2.4e-158 527.5 0.0 3.2e-158 527.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OAJ18284.1 - 0.00061 18.9 0.0 0.097 11.7 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase RRM_1 PF00076.22 OAJ18285.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_11 PF08241.12 OAJ18286.1 - 1.1e-19 70.8 0.1 8.2e-19 68.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ18286.1 - 2.9e-19 69.6 0.0 1e-18 67.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ18286.1 - 7.5e-16 58.3 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ18286.1 - 5.9e-11 43.0 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ18286.1 - 1.4e-10 40.9 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAJ18286.1 - 6.6e-09 35.8 0.0 9.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OAJ18286.1 - 0.00024 20.8 0.0 0.0011 18.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OAJ18286.1 - 0.00033 20.2 0.0 0.0014 18.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 OAJ18286.1 - 0.0005 18.7 0.0 0.00065 18.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 OAJ18286.1 - 0.00054 19.5 0.0 0.0016 17.9 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 OAJ18286.1 - 0.0057 16.7 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ18286.1 - 0.0073 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 OAJ18286.1 - 0.0075 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 OAJ18286.1 - 0.059 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 OAJ18286.1 - 0.12 13.4 0.0 0.32 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 OAJ18286.1 - 0.15 11.9 0.0 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.13 OAJ18286.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Transglut_core3 PF13471.6 OAJ18287.1 - 0.029 14.3 0.7 0.071 13.0 0.1 1.9 1 1 0 2 2 2 0 Transglutaminase-like superfamily zf-C2H2 PF00096.26 OAJ18288.1 - 0.62 10.6 5.2 1.5 9.5 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1654 PF07867.11 OAJ18323.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) MSSP PF03940.13 OAJ18324.1 - 8.7 6.0 14.4 0.089 12.4 2.4 2.3 2 1 0 2 2 2 0 Male specific sperm protein Brix PF04427.18 OAJ18325.1 - 1.7e-42 145.7 0.0 2.1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain SE PF08491.10 OAJ18326.1 - 1e-80 270.8 0.0 7.2e-37 126.9 0.0 3.2 3 0 0 3 3 3 3 Squalene epoxidase DAO PF01266.24 OAJ18326.1 - 1.5e-11 44.5 0.9 4.6e-08 33.0 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ18326.1 - 2.4e-10 40.2 0.3 3.6e-06 26.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ18326.1 - 2.3e-05 24.5 0.9 6e-05 23.2 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ18326.1 - 0.00063 18.9 2.2 0.0023 17.1 1.6 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAJ18326.1 - 0.00074 18.7 0.8 0.0011 18.2 0.4 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAJ18326.1 - 0.00095 18.5 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAJ18326.1 - 0.00098 18.8 0.2 0.0023 17.6 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ18326.1 - 0.0012 18.7 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAJ18326.1 - 0.0013 18.1 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAJ18326.1 - 0.0015 18.0 1.4 0.0027 17.1 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ18326.1 - 0.002 18.6 0.2 0.0071 16.9 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAJ18326.1 - 0.0026 16.7 0.8 0.024 13.5 0.2 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Rossmann-like PF10727.9 OAJ18326.1 - 0.0063 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAJ18326.1 - 0.0086 16.3 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OAJ18326.1 - 0.029 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 OAJ18326.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.15 OAJ18326.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAJ18326.1 - 0.23 11.5 0.0 0.42 10.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAJ18326.1 - 0.36 9.8 1.8 0.41 9.6 0.4 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Med10 PF09748.9 OAJ18327.1 - 1.3e-18 67.1 0.1 1.8e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex EMG1 PF03587.14 OAJ18328.1 - 4.6e-77 258.1 0.0 5.8e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF3498 PF12004.8 OAJ18328.1 - 0.2 10.8 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) RNase_PH PF01138.21 OAJ18329.1 - 1e-22 81.1 0.0 1.5e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Arf PF00025.21 OAJ18330.1 - 3.5e-77 257.8 0.0 4e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAJ18330.1 - 2.1e-15 57.0 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ18330.1 - 7.2e-13 48.5 0.0 7.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OAJ18330.1 - 4.7e-12 45.7 0.8 1.8e-07 30.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAJ18330.1 - 2.4e-11 43.4 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ18330.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ18330.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAJ18330.1 - 0.0011 18.4 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DUF4185 PF13810.6 OAJ18330.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) PP2C PF00481.21 OAJ18331.1 - 1.2e-66 225.0 0.4 5.2e-51 173.8 0.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C E3_UbLigase_RBR PF18091.1 OAJ18331.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain Pap_E4 PF02711.14 OAJ18331.1 - 0.18 12.8 1.7 35 5.4 0.0 2.9 2 0 0 2 2 2 0 E4 protein BAR PF03114.18 OAJ18332.1 - 2.8e-13 50.1 0.9 4.5e-13 49.4 0.9 1.3 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OAJ18332.1 - 0.00019 20.7 0.2 0.00036 19.8 0.2 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 OAJ18332.1 - 0.002 17.8 0.4 0.0033 17.2 0.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF4349 PF14257.6 OAJ18332.1 - 0.056 12.9 3.7 0.12 11.8 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Med3 PF11593.8 OAJ18332.1 - 5.3 6.1 7.9 12 4.9 7.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Acetyltransf_5 PF13444.6 OAJ18333.1 - 0.00011 22.9 0.0 0.00054 20.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ18333.1 - 0.00017 21.5 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ18333.1 - 0.027 14.9 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ18333.1 - 0.17 12.1 0.0 1.3 9.3 0.1 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Methyltransf_31 PF13847.6 OAJ18335.1 - 3.9e-17 62.5 0.0 5.4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ18335.1 - 1e-14 55.0 0.0 1.8e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ18335.1 - 6.2e-13 49.2 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ18335.1 - 7.2e-12 45.9 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ18335.1 - 1.2e-09 38.3 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ18335.1 - 5.7e-06 26.2 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OAJ18335.1 - 8.3e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAJ18335.1 - 8.5e-05 22.2 0.0 0.00019 21.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 OAJ18335.1 - 0.00017 21.3 0.0 0.00036 20.3 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 OAJ18335.1 - 0.00033 20.2 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OAJ18335.1 - 0.0024 17.2 0.0 0.0045 16.3 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAJ18335.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 OAJ18335.1 - 0.038 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase CheR PF01739.18 OAJ18335.1 - 0.045 13.2 0.0 4.1 6.8 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain CAV_VP3 PF04771.12 OAJ18335.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 1 0 Chicken anaemia virus VP-3 protein Methyltransf_9 PF08003.11 OAJ18335.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltr_RsmB-F PF01189.17 OAJ18335.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DNA_gyraseA_C PF03989.13 OAJ18359.1 - 0.11 12.0 0.2 0.41 10.1 0.1 1.9 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller RVT_2 PF07727.14 OAJ18360.1 - 5.7e-70 235.7 0.0 7.9e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ18361.1 - 4.9e-07 29.6 0.0 8.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ18361.1 - 5.1e-06 27.0 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 OAJ18361.1 - 2.1e-05 24.4 2.3 4e-05 23.5 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 OAJ18361.1 - 7.6e-05 23.3 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_6 PF15288.6 OAJ18361.1 - 0.0018 18.1 0.8 0.0064 16.3 0.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ18361.1 - 0.0025 17.6 1.6 0.005 16.6 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAJ18361.1 - 0.012 15.9 1.0 0.072 13.4 0.0 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_3 PF13917.6 OAJ18361.1 - 0.026 14.5 0.2 0.062 13.3 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 OAJ18361.1 - 0.048 13.6 1.6 0.13 12.2 1.6 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle Myb_DNA-bind_5 PF13873.6 OAJ18362.1 - 0.006 16.6 0.2 0.075 13.1 0.2 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ18362.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain BUD22 PF09073.10 OAJ18362.1 - 0.15 11.3 12.5 0.21 10.9 12.5 1.2 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 OAJ18362.1 - 0.17 12.6 14.3 0.3 11.8 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 OAJ18362.1 - 0.56 8.3 10.1 0.68 8.1 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 OAJ18363.1 - 5.8e-06 26.1 2.4 1.5e-05 24.8 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ18363.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type BUD22 PF09073.10 OAJ18363.1 - 0.24 10.7 9.5 0.044 13.1 4.1 2.0 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 OAJ18363.1 - 0.37 9.0 6.0 0.78 8.0 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ18363.1 - 0.42 10.0 12.4 0.015 14.7 5.0 2.0 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 OAJ18363.1 - 0.43 8.7 9.0 0.16 10.2 5.9 1.7 2 0 0 2 2 2 0 Nop14-like family RT_RNaseH PF17917.1 OAJ18364.1 - 1.7e-28 98.9 0.1 4.8e-28 97.5 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ18364.1 - 3.7e-20 71.8 0.0 8e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18364.1 - 2.6e-17 62.7 0.2 6.5e-17 61.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ18364.1 - 4e-17 62.5 0.2 7.3e-17 61.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ18364.1 - 1.2e-11 44.9 0.0 3.7e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ18364.1 - 1.1e-05 25.5 0.0 3.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 OAJ18364.1 - 0.016 15.1 0.1 0.045 13.7 0.1 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 OAJ18366.1 - 2.5e-06 27.4 0.0 1.7e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ18366.1 - 3.9e-05 23.9 0.0 0.0035 17.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UPF0489 PF12640.7 OAJ18394.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 UPF0489 domain rve PF00665.26 OAJ18395.1 - 5.6e-12 45.9 0.0 6.3e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Transcript_VP30 PF11507.8 OAJ18395.1 - 0.024 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 gag_pre-integrs PF13976.6 OAJ18396.1 - 5.5e-05 22.9 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAJ18396.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type L27_2 PF09045.10 OAJ18396.1 - 0.022 14.7 0.0 0.08 12.9 0.0 2.0 1 0 0 1 1 1 0 L27_2 DUF883 PF05957.13 OAJ18399.1 - 1.4 9.6 9.1 7.2 7.3 3.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GFA PF04828.14 OAJ18400.1 - 0.027 14.8 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme 2OG-FeII_Oxy_2 PF13532.6 OAJ18433.1 - 2e-25 90.1 0.0 3.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSP90 PF00183.18 OAJ18434.1 - 2e-51 175.5 0.2 3.6e-34 118.6 0.4 2.2 1 1 1 2 2 2 2 Hsp90 protein Scm3 PF10384.9 OAJ18434.1 - 4.5e-07 29.5 0.8 2.7e-06 27.0 0.8 2.2 1 1 0 1 1 1 1 Centromere protein Scm3 F_actin_cap_B PF01115.17 OAJ18435.1 - 4.8e-81 271.9 0.0 5.8e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit TRAM_LAG1_CLN8 PF03798.16 OAJ18436.1 - 5.2e-41 140.6 17.6 6.4e-41 140.3 17.6 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 OAJ18436.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein ANAPC4_WD40 PF12894.7 OAJ18437.1 - 1.9e-09 37.7 0.0 0.28 11.5 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ18437.1 - 9.5e-08 32.6 7.0 0.061 14.2 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ18437.1 - 2.3e-06 27.9 0.6 0.00065 20.1 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain RAB3GAP2_N PF14655.6 OAJ18437.1 - 1.1 8.5 2.4 19 4.4 0.0 2.7 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus HTH_Tnp_Tc5 PF03221.16 OAJ18438.1 - 3.4e-05 23.8 0.1 0.00035 20.6 0.0 2.3 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain RPOL_N PF14700.6 OAJ18439.1 - 0.022 14.2 0.1 0.024 14.0 0.1 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF2201_N PF13203.6 OAJ18439.1 - 0.024 14.2 1.4 0.025 14.2 1.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_S10 PF00338.22 OAJ18462.1 - 9.7e-23 80.3 0.0 1.8e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Amino_oxidase PF01593.24 OAJ18464.1 - 3.3e-14 53.0 0.0 4.1e-12 46.1 0.0 3.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ18464.1 - 1e-11 44.8 0.1 2.2e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ18464.1 - 1.7e-08 34.0 0.4 1.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ18464.1 - 2.6e-07 30.6 0.0 8.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ18464.1 - 9.4e-05 21.7 1.2 0.00028 20.1 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ18464.1 - 0.0013 19.3 3.4 0.0021 18.6 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ18464.1 - 0.0019 17.0 0.2 0.0028 16.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ18464.1 - 0.0048 16.2 0.1 0.0084 15.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAJ18464.1 - 0.0057 15.9 1.0 0.01 15.1 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAJ18464.1 - 0.012 14.4 0.9 1.5 7.6 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 OAJ18464.1 - 0.018 15.3 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 OAJ18464.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ18464.1 - 0.038 13.1 0.2 0.068 12.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAJ18464.1 - 0.046 13.4 0.4 0.098 12.3 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OAJ18464.1 - 0.063 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 OAJ18464.1 - 0.077 12.2 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 OAJ18464.1 - 0.17 12.4 0.2 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAJ18464.1 - 0.18 11.8 0.8 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 OAJ18464.1 - 0.18 12.4 0.3 0.46 11.1 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 OAJ18464.1 - 0.27 10.3 3.5 0.24 10.4 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A AA_permease_2 PF13520.6 OAJ18465.1 - 1.5e-76 258.0 33.9 1.9e-76 257.6 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ18466.1 - 1.5e-42 145.9 21.1 1.9e-42 145.6 21.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ18466.1 - 2.1e-09 36.5 18.5 2.8e-09 36.1 18.5 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.20 OAJ18467.1 - 2.6e-30 106.0 0.0 2.6e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain 3-HAO PF06052.12 OAJ18468.1 - 1.4e-58 196.8 0.0 1.6e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 OAJ18468.1 - 3.8e-07 29.7 0.1 5.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAJ18468.1 - 0.0078 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAJ18468.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 OAJ18468.1 - 0.057 13.6 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family DEAD PF00270.29 OAJ18469.1 - 1.2e-14 54.5 0.0 1.2e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ18469.1 - 0.00025 21.4 0.0 0.00085 19.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lin-8 PF03353.15 OAJ18469.1 - 0.49 9.9 14.3 1.1 8.7 14.3 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BRF1 PF07741.13 OAJ18469.1 - 0.53 10.7 9.2 0.081 13.3 4.6 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain HA2 PF04408.23 OAJ18469.1 - 0.64 10.3 4.0 20 5.5 2.2 2.7 2 0 0 2 2 2 0 Helicase associated domain (HA2) MecA PF05389.12 OAJ18469.1 - 0.77 9.4 5.0 1.6 8.3 5.0 1.5 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) FAM60A PF15396.6 OAJ18469.1 - 5.2 7.0 6.2 11 5.9 6.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Metallopep PF12044.8 OAJ18470.1 - 5.6e-10 38.4 0.0 4.6e-09 35.4 0.0 1.9 2 0 0 2 2 2 2 Putative peptidase family Phage_integrase PF00589.22 OAJ18471.1 - 3.1e-05 23.8 0.0 7.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family PhyH PF05721.13 OAJ18500.1 - 4.3e-08 33.7 0.0 1.5e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DIOX_N PF14226.6 OAJ18500.1 - 0.18 12.5 0.0 0.45 11.3 0.0 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF1325 PF07039.11 OAJ18501.1 - 9e-30 103.5 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 OAJ18501.1 - 0.026 15.0 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Agenet domain PGM_PMM_I PF02878.16 OAJ18502.1 - 7.6e-38 129.3 0.3 1.3e-37 128.6 0.3 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OAJ18502.1 - 2.3e-23 82.8 0.1 1.4e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAJ18502.1 - 9.4e-10 38.7 0.0 2.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OAJ18502.1 - 2e-07 31.1 0.2 1.1e-06 28.8 0.1 2.3 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GATA PF00320.27 OAJ18503.1 - 1.1e-12 47.4 5.7 2e-12 46.5 5.7 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-rbx1 PF12678.7 OAJ18504.1 - 2.9e-06 27.5 3.8 6.4e-06 26.4 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ18504.1 - 3.6e-06 27.2 4.3 3.6e-06 27.2 4.3 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ18504.1 - 2.5e-05 24.0 3.3 2.5e-05 24.0 3.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ18504.1 - 0.0015 18.4 2.8 0.0015 18.4 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ18504.1 - 0.0018 18.1 1.7 0.0018 18.1 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ18504.1 - 0.0097 15.5 5.7 0.022 14.4 5.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OAJ18504.1 - 0.013 15.5 2.5 0.013 15.5 2.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ18504.1 - 0.02 15.0 1.0 0.05 13.7 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAJ18504.1 - 2.1 8.5 4.7 1.5 8.9 1.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zinc_ribbon_16 PF17034.5 OAJ18504.1 - 5.6 7.2 7.3 2.1 8.6 3.8 2.1 2 1 0 2 2 2 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 OAJ18504.1 - 8.8 6.3 11.4 0.038 13.9 2.5 1.6 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 Putative_PNPOx PF01243.20 OAJ18505.1 - 0.00046 20.3 0.0 0.16 12.1 0.0 3.2 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase MIF4G PF02854.19 OAJ18506.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 MIF4G domain EAR PF07897.11 OAJ18506.1 - 0.91 9.2 3.7 1.8 8.2 1.0 2.4 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression DUF543 PF04418.12 OAJ18507.1 - 6.9e-29 99.7 0.2 1.8e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4536 PF15055.6 OAJ18507.1 - 9.7e-06 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF883 PF05957.13 OAJ18507.1 - 0.26 11.9 3.3 5 7.8 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA PF00004.29 OAJ18508.1 - 3.5e-84 279.9 0.0 1.6e-41 141.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ18508.1 - 1.3e-25 88.9 3.7 1.1e-11 44.4 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 OAJ18508.1 - 4.4e-14 52.7 0.1 3.9e-06 26.9 0.0 4.8 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ18508.1 - 2.1e-13 50.3 0.0 4.8e-06 26.4 0.0 3.2 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ18508.1 - 3.5e-13 50.3 2.4 6e-07 30.0 0.4 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ18508.1 - 4e-09 36.8 0.6 0.0016 18.7 0.1 4.4 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ18508.1 - 8.1e-08 31.9 0.1 0.00055 19.2 0.0 2.6 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_25 PF13481.6 OAJ18508.1 - 2.1e-07 30.7 4.9 0.067 12.8 0.1 4.7 3 2 1 4 4 4 2 AAA domain AAA_33 PF13671.6 OAJ18508.1 - 1.2e-06 28.7 0.0 0.013 15.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OAJ18508.1 - 1.3e-06 28.6 0.0 0.052 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAJ18508.1 - 5.2e-06 26.5 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAJ18508.1 - 6.8e-06 25.9 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 OAJ18508.1 - 1.1e-05 25.4 0.1 0.063 13.2 0.0 3.4 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_18 PF13238.6 OAJ18508.1 - 3.1e-05 24.5 0.0 0.012 16.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ18508.1 - 3.2e-05 24.3 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 OAJ18508.1 - 3.7e-05 23.2 2.7 0.096 12.1 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAJ18508.1 - 0.00011 22.5 0.0 0.17 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAJ18508.1 - 0.00019 21.0 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAJ18508.1 - 0.00021 21.1 0.0 0.0098 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ18508.1 - 0.00074 18.8 0.0 0.058 12.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 OAJ18508.1 - 0.0019 18.2 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAJ18508.1 - 0.0031 17.5 0.1 4.7 7.1 0.0 3.2 2 1 0 2 2 2 1 NACHT domain ATPase PF06745.13 OAJ18508.1 - 0.0038 16.6 0.0 2.2 7.6 0.0 3.0 4 0 0 4 4 3 1 KaiC AAA_3 PF07726.11 OAJ18508.1 - 0.0039 17.1 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 OAJ18508.1 - 0.005 17.3 0.1 4.1 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 OAJ18508.1 - 0.0085 15.8 0.1 7.5 6.2 0.0 3.8 3 1 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OAJ18508.1 - 0.0089 16.1 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 OAJ18508.1 - 0.011 16.2 0.0 0.88 10.1 0.0 3.0 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 OAJ18508.1 - 0.017 15.0 0.7 1.3 8.9 0.0 3.6 3 2 1 5 5 4 0 NTPase AAA_11 PF13086.6 OAJ18508.1 - 0.022 14.5 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ18508.1 - 0.027 13.9 0.4 0.79 9.1 0.1 2.5 3 0 0 3 3 2 0 PhoH-like protein Parvo_NS1 PF01057.17 OAJ18508.1 - 0.027 13.5 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 OAJ18508.1 - 0.038 13.7 0.0 0.67 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAJ18508.1 - 0.048 14.0 0.3 0.99 9.7 0.2 2.8 2 1 1 3 3 2 0 AAA domain PduV-EutP PF10662.9 OAJ18508.1 - 0.14 11.9 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAJ18508.1 - 0.17 11.0 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Peptidase_M13_N PF05649.13 OAJ18509.1 - 2.6e-85 287.4 0.0 3.4e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAJ18509.1 - 4.5e-57 193.0 0.0 7.9e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF4164 PF13747.6 OAJ18509.1 - 0.4 11.0 2.2 0.46 10.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF2040 PF09745.9 OAJ18510.1 - 8.1e-32 109.8 20.2 8.1e-32 109.8 20.2 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) KDZ PF18758.1 OAJ18531.1 - 1.2e-22 80.7 0.0 1.9e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ18531.1 - 4.5e-10 39.6 0.1 9.2e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ18531.1 - 7.2e-07 29.3 0.4 2.3e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CENP-M PF11111.8 OAJ18531.1 - 0.09 12.0 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Centromere protein M (CENP-M) tRNA-synt_1 PF00133.22 OAJ18532.1 - 4.7e-18 64.8 0.1 5.6e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Zn_clus PF00172.18 OAJ18534.1 - 3.4e-05 23.9 8.0 6e-05 23.1 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OAJ18534.1 - 1.1 9.2 20.6 1.1 9.2 13.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ18534.1 - 5.7 6.5 22.8 0.87 9.1 15.0 2.2 2 0 0 2 2 2 0 Spt20 family tRNA-synt_1 PF00133.22 OAJ18535.1 - 1.4e-112 376.9 0.0 1.7e-112 376.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) PITH PF06201.13 OAJ18536.1 - 2.8e-36 125.0 0.0 5.4e-18 65.7 0.0 3.4 2 1 0 2 2 2 2 PITH domain Anticodon_1 PF08264.13 OAJ18536.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Secapin PF17521.2 OAJ18536.1 - 0.065 13.0 0.6 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Honey bee peptides Cyclin_N PF00134.23 OAJ18537.1 - 2.4e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OAJ18537.1 - 1.4e-08 35.1 0.1 4.3e-06 27.0 0.1 2.7 3 0 0 3 3 3 2 Cyclin C-terminal domain TFIIB PF00382.19 OAJ18537.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF4592 PF15262.6 OAJ18537.1 - 2.9 8.6 6.9 0.42 11.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) Trimer_CC PF08954.11 OAJ18538.1 - 0.089 12.4 0.1 3.2 7.4 0.0 2.8 2 1 1 3 3 3 0 Trimerisation motif E2_bind PF08825.10 OAJ18538.1 - 0.1 12.7 0.8 0.18 12.0 0.8 1.4 1 0 0 1 1 1 0 E2 binding domain HTH_37 PF13744.6 OAJ18538.1 - 0.18 11.8 0.3 0.18 11.8 0.3 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain DPBB_1 PF03330.18 OAJ18539.1 - 0.00026 21.2 0.0 0.00048 20.4 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ18539.1 - 0.0051 16.6 0.2 0.0084 16.0 0.2 1.4 1 1 0 1 1 1 1 Barwin family RRM_1 PF00076.22 OAJ18564.1 - 2.7e-26 91.1 0.0 2.2e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sox17_18_mid PF12067.8 OAJ18564.1 - 0.42 10.7 2.5 0.84 9.7 0.0 2.7 2 0 0 2 2 2 0 Sox 17/18 central domain COX14 PF14880.6 OAJ18565.1 - 0.0038 17.0 0.2 0.0064 16.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Rep_fac_C PF08542.11 OAJ18566.1 - 4.7e-18 65.4 0.0 9.8e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAJ18566.1 - 1.6e-17 64.2 0.0 6.5e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ18566.1 - 2.5e-15 56.6 0.0 3.3e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OAJ18566.1 - 8.8e-10 38.8 0.0 2.4e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 OAJ18566.1 - 1.1e-05 25.3 0.2 0.00044 20.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OAJ18566.1 - 2.6e-05 23.5 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAJ18566.1 - 3.1e-05 23.8 0.0 7.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OAJ18566.1 - 3.9e-05 23.9 0.1 0.00013 22.3 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 OAJ18566.1 - 5.8e-05 23.1 0.1 0.00024 21.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAJ18566.1 - 9.8e-05 22.1 0.0 0.00025 20.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAJ18566.1 - 0.00012 22.5 0.0 0.00038 20.9 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 OAJ18566.1 - 0.00023 21.0 0.0 0.00086 19.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 OAJ18566.1 - 0.00034 20.9 0.1 0.088 13.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAJ18566.1 - 0.0004 20.2 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ18566.1 - 0.00051 20.1 0.0 0.002 18.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 OAJ18566.1 - 0.00061 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ18566.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 OAJ18566.1 - 0.0055 16.7 0.0 0.25 11.3 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 OAJ18566.1 - 0.0056 16.1 0.1 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 OAJ18566.1 - 0.0068 16.8 0.0 0.016 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ18566.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 OAJ18566.1 - 0.023 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 OAJ18566.1 - 0.045 13.5 0.1 0.46 10.2 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 OAJ18566.1 - 0.05 14.1 0.0 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 OAJ18566.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAJ18566.1 - 0.092 12.3 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAJ18566.1 - 0.12 11.7 0.0 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.7 OAJ18566.1 - 0.13 11.1 0.1 2.9 6.7 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain TIP41 PF04176.13 OAJ18567.1 - 1.3e-46 158.2 0.0 5.7e-45 152.9 0.0 3.0 2 1 0 2 2 2 1 TIP41-like family Nop14 PF04147.12 OAJ18568.1 - 0.026 12.7 14.6 0.036 12.3 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ18568.1 - 0.11 11.8 10.9 0.19 11.0 10.9 1.3 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 OAJ18568.1 - 0.22 9.6 2.4 0.32 9.0 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.19 OAJ18568.1 - 0.34 11.5 11.0 0.86 10.2 11.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein SAPS PF04499.15 OAJ18568.1 - 0.52 9.0 4.5 0.7 8.6 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 OAJ18568.1 - 1.5 8.0 4.5 2.6 7.2 4.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 OAJ18568.1 - 2.2 7.9 8.2 0.27 10.9 2.5 2.1 2 0 0 2 2 2 0 FAM176 family Mcp5_PH PF12814.7 OAJ18569.1 - 2.4e-43 147.1 0.2 8.6e-43 145.3 0.0 2.1 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 OAJ18569.1 - 0.058 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 PH domain INCENP_ARK-bind PF03941.15 OAJ18571.1 - 6.5e-11 42.0 0.3 1.6e-10 40.7 0.3 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DNA_primase_S PF01896.19 OAJ18572.1 - 9.8e-54 182.1 0.0 2.2e-53 180.9 0.0 1.6 1 1 0 1 1 1 1 DNA primase small subunit Ctr PF04145.15 OAJ18573.1 - 2e-18 67.4 0.2 1.7e-17 64.4 0.2 2.0 1 1 0 1 1 1 1 Ctr copper transporter family RVT_1 PF00078.27 OAJ18574.1 - 1.2e-14 54.3 0.0 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nucleo_P87 PF07267.11 OAJ18574.1 - 1.5 7.6 6.4 2.4 6.9 6.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CBFD_NFYB_HMF PF00808.23 OAJ18575.1 - 1.2e-07 31.9 0.3 2.1e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 OAJ18575.1 - 0.0044 16.4 19.7 0.0052 16.2 19.7 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 OAJ18575.1 - 0.0073 16.4 14.5 0.0092 16.0 14.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 OAJ18575.1 - 0.011 15.8 0.9 0.011 15.8 0.9 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CDC27 PF09507.10 OAJ18575.1 - 0.039 13.3 17.3 0.04 13.3 17.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Histone PF00125.24 OAJ18575.1 - 0.07 13.5 0.2 0.07 13.5 0.2 2.3 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PIEZO PF15917.5 OAJ18575.1 - 0.31 10.5 6.9 0.46 9.9 6.9 1.2 1 0 0 1 1 1 0 Piezo Afi1 PF07792.12 OAJ18575.1 - 1.1 9.8 8.9 13 6.2 8.9 2.2 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking GRAB PF10375.9 OAJ18576.1 - 7.6e-06 25.6 1.3 7.6e-06 25.6 1.3 2.8 3 0 0 3 3 3 1 GRIP-related Arf-binding domain Macoilin PF09726.9 OAJ18576.1 - 0.00035 19.3 6.8 0.00035 19.3 6.8 3.6 3 1 1 4 4 3 1 Macoilin family DUF4407 PF14362.6 OAJ18576.1 - 0.002 17.6 17.1 0.002 17.6 17.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OAJ18576.1 - 0.0022 17.9 1.2 0.0022 17.9 1.2 4.5 3 2 0 5 5 5 1 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 OAJ18576.1 - 0.31 11.3 44.5 0.72 10.1 9.4 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein Serglycin PF04360.12 OAJ18576.1 - 0.62 10.0 0.0 0.62 10.0 0.0 3.7 3 1 1 4 4 3 0 Serglycin Phage_GP20 PF06810.11 OAJ18576.1 - 1.1 9.1 14.1 2.4 7.9 0.1 3.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.12 OAJ18576.1 - 5.3 7.1 13.5 7.4 6.6 0.4 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OAJ18576.1 - 6.5 6.8 11.5 6.5 6.8 0.9 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 OAJ18576.1 - 8.1 5.7 18.1 0.34 10.2 3.7 2.3 1 1 0 2 2 2 0 FAM76 protein BBP1_C PF15272.6 OAJ18576.1 - 9.1 6.1 22.9 0.21 11.4 14.9 2.3 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Serine_rich PF08824.10 OAJ18606.1 - 0.085 12.9 0.6 0.34 10.9 0.1 2.1 2 1 1 3 3 3 0 Serine rich protein interaction domain MARVEL PF01284.23 OAJ18607.1 - 2.6e-07 30.8 16.8 4.1e-07 30.1 16.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Wzy_C PF04932.15 OAJ18607.1 - 0.97 9.1 6.6 0.42 10.2 2.3 2.1 2 1 0 2 2 2 0 O-Antigen ligase DUF621 PF04789.15 OAJ18608.1 - 9.9 5.2 8.6 11 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF621) YjcB PF15940.5 OAJ18609.1 - 0.072 13.3 1.7 0.45 10.7 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function SQS_PSY PF00494.19 OAJ18610.1 - 2e-32 112.8 0.1 5.7e-32 111.2 0.0 1.8 2 0 0 2 2 2 1 Squalene/phytoene synthase Coatomer_WDAD PF04053.14 OAJ18611.1 - 7.6e-138 460.3 0.0 1.2e-137 459.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAJ18611.1 - 4.5e-96 322.1 0.0 5.6e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAJ18611.1 - 2.1e-42 142.2 11.8 1.1e-08 35.5 0.3 8.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18611.1 - 8.4e-13 48.4 0.2 0.0011 19.3 0.0 6.5 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OAJ18611.1 - 0.0099 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_2 PF07719.17 OAJ18611.1 - 0.1 12.8 0.1 13 6.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup160 PF11715.8 OAJ18611.1 - 0.18 10.4 5.1 1.5 7.4 0.0 3.4 1 1 3 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 OAJ18611.1 - 2.3 9.3 8.4 1.9e+02 3.3 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PGA2 PF07543.12 OAJ18612.1 - 0.02 14.9 2.4 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 SOG2 PF10428.9 OAJ18612.1 - 0.04 13.1 11.0 0.063 12.5 11.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 OAJ18612.1 - 0.75 8.8 7.6 1.1 8.2 7.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 OAJ18612.1 - 1 9.3 16.3 0.11 12.5 11.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 OAJ18612.1 - 4.3 5.8 14.0 0.86 8.1 10.6 1.4 2 0 0 2 2 2 0 Macoilin family Hid1 PF12722.7 OAJ18612.1 - 7.1 4.6 10.7 9.1 4.3 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 OAJ18612.1 - 9.2 5.4 7.9 15 4.6 7.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M20 PF01546.28 OAJ18613.1 - 1.4e-31 109.8 0.0 1.8e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAJ18613.1 - 2.4e-13 49.9 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Alk_phosphatase PF00245.20 OAJ18614.1 - 1.3e-78 264.9 0.1 5.9e-78 262.7 0.1 1.8 1 1 0 1 1 1 1 Alkaline phosphatase AAA PF00004.29 OAJ18615.1 - 6.1e-41 139.9 0.0 1.3e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ18615.1 - 1.3e-06 28.1 0.1 3.5e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAJ18615.1 - 4.2e-05 23.6 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ18615.1 - 9.2e-05 22.7 0.0 0.0047 17.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ18615.1 - 0.00024 21.2 0.0 0.00083 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAJ18615.1 - 0.00089 19.7 0.8 0.022 15.2 0.1 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAJ18615.1 - 0.0016 17.6 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAJ18615.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAJ18615.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ18615.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ18615.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ18615.1 - 0.048 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAJ18615.1 - 0.056 12.8 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAJ18615.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 OAJ18615.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ18615.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAJ18615.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 OAJ18615.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAJ18615.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Glutaredoxin PF00462.24 OAJ18616.1 - 2.5e-18 66.0 0.0 3.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OAJ18616.1 - 0.00017 22.0 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OAJ18616.1 - 0.00075 19.9 0.1 0.0016 18.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_2 PF13409.6 OAJ18616.1 - 0.0023 18.2 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TraF PF13728.6 OAJ18616.1 - 0.0093 15.8 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein GST_N_3 PF13417.6 OAJ18616.1 - 0.015 15.7 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 OAJ18616.1 - 0.052 13.7 0.6 1.6 8.8 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 OAJ18616.1 - 0.055 13.6 0.0 0.084 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 OAJ18616.1 - 0.07 12.9 0.1 0.35 10.6 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain bZIP_1 PF00170.21 OAJ18637.1 - 2.4e-07 30.7 25.1 4.2e-07 30.0 8.2 3.1 2 1 1 3 3 3 2 bZIP transcription factor Hap4_Hap_bind PF10297.9 OAJ18637.1 - 1.5e-06 28.1 4.8 1.5e-06 28.1 4.8 2.8 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 CBM60 PF16841.5 OAJ18638.1 - 0.12 12.9 0.0 9.6 6.7 0.0 2.2 1 1 1 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding SNF2_N PF00176.23 OAJ18639.1 - 6.3e-63 212.6 1.7 1.2e-62 211.7 1.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 OAJ18639.1 - 1.8e-51 174.0 20.6 1.8e-51 174.0 20.6 2.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 OAJ18639.1 - 7.2e-17 61.7 0.0 1.7e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ18639.1 - 1.1e-06 28.8 0.0 2.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ18639.1 - 0.021 14.0 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Paramyx_P_V_C PF03210.13 OAJ18639.1 - 0.69 9.7 5.5 3.2 7.5 1.7 2.6 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal LIP PF03583.14 OAJ18640.1 - 1.5e-45 155.8 0.1 2e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ18640.1 - 0.00012 21.6 0.2 0.0076 15.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ18640.1 - 0.084 12.1 0.6 5.9 6.1 0.0 2.7 3 1 0 3 3 3 0 Serine aminopeptidase, S33 PIP5K PF01504.18 OAJ18641.1 - 6.8e-43 146.8 0.1 1.8e-33 115.9 0.0 3.1 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAJ18641.1 - 7.5e-27 94.1 0.2 1.2e-26 93.4 0.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAJ18641.1 - 1.5e-15 57.0 9.3 1.5e-15 57.0 9.3 1.8 2 0 0 2 2 2 1 FYVE zinc finger ANAPC_CDC26 PF10471.9 OAJ18641.1 - 0.039 14.8 7.0 0.052 14.4 2.2 3.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 OAJ18641.1 - 5.5 6.5 10.0 0.16 11.6 3.3 1.8 2 0 0 2 2 2 0 Spt20 family APG5 PF04106.12 OAJ18671.1 - 3e-63 213.5 0.0 3.9e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 adh_short PF00106.25 OAJ18672.1 - 6.9e-25 87.7 0.0 8.3e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ18672.1 - 1.2e-20 74.1 0.0 1.5e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mon2_C PF16206.5 OAJ18673.1 - 0.064 11.4 0.0 0.094 10.8 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein V-ATPase_H_N PF03224.14 OAJ18673.1 - 0.14 11.5 0.0 5.3 6.2 0.0 2.3 2 0 0 2 2 2 0 V-ATPase subunit H DUF572 PF04502.13 OAJ18673.1 - 0.28 10.8 10.8 0.47 10.0 10.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GRP PF07172.11 OAJ18673.1 - 7.7 7.3 13.2 0.34 11.6 7.2 1.9 2 0 0 2 2 2 0 Glycine rich protein family COPIIcoated_ERV PF07970.12 OAJ18674.1 - 8.2e-38 130.5 0.3 1.3e-37 129.8 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAJ18674.1 - 1.2e-24 86.4 0.0 2.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NIF3 PF01784.18 OAJ18675.1 - 5.9e-58 196.4 0.0 7.2e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RVT_1 PF00078.27 OAJ18676.1 - 3.5e-28 98.6 0.0 6.4e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ18676.1 - 1.7e-16 60.1 1.4 2.3e-15 56.5 0.1 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 OAJ18676.1 - 5.5e-08 33.1 0.0 2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 OAJ18676.1 - 0.011 16.4 0.1 0.041 14.6 0.1 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 OAJ18676.1 - 0.024 14.2 0.0 0.061 12.8 0.0 1.8 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PQ-loop PF04193.14 OAJ18678.1 - 6e-19 67.6 15.8 4.1e-10 39.3 0.2 3.2 3 0 0 3 3 3 2 PQ loop repeat BSP_II PF05432.11 OAJ18678.1 - 0.0023 17.7 1.3 0.0033 17.2 1.3 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF3328 PF11807.8 OAJ18678.1 - 0.0044 16.8 1.2 2 8.1 0.5 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3328) Bindin PF02084.15 OAJ18678.1 - 0.012 15.9 5.6 0.021 15.1 5.6 1.3 1 0 0 1 1 1 0 Bindin DUF2613 PF11021.8 OAJ18678.1 - 0.072 13.2 9.5 0.18 11.9 8.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Syndecan PF01034.20 OAJ18678.1 - 0.21 11.6 0.0 0.21 11.6 0.0 3.0 3 0 0 3 3 2 0 Syndecan domain FAM176 PF14851.6 OAJ18678.1 - 0.33 10.6 4.3 1.5 8.4 2.5 2.3 2 0 0 2 2 2 0 FAM176 family Astro_capsid_p PF12226.8 OAJ18678.1 - 0.43 9.7 4.3 0.69 9.0 4.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 OAJ18678.1 - 0.99 7.4 6.9 1.5 6.9 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2207 PF09972.9 OAJ18678.1 - 1 8.0 10.2 0.4 9.4 0.0 3.4 2 2 2 4 4 4 0 Predicted membrane protein (DUF2207) DUF1218 PF06749.12 OAJ18678.1 - 1.1 9.9 9.3 12 6.5 1.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF4637 PF15470.6 OAJ18678.1 - 1.2 8.8 6.2 1.9 8.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Annexin PF00191.20 OAJ18679.1 - 1.5e-53 178.8 0.2 1.4e-13 50.7 0.1 4.1 4 0 0 4 4 4 4 Annexin Peptidase_M43 PF05572.13 OAJ18680.1 - 6.1e-17 62.0 0.1 8.9e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAJ18680.1 - 0.0011 19.1 0.6 0.002 18.3 0.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAJ18680.1 - 0.0015 19.1 0.1 0.0048 17.4 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ18680.1 - 0.0043 16.9 0.1 0.0064 16.3 0.1 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.16 OAJ18680.1 - 0.05 13.7 0.8 0.22 11.6 0.3 2.2 2 1 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.6 OAJ18680.1 - 0.067 12.8 0.2 0.096 12.3 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 OAJ18680.1 - 0.2 10.9 0.5 0.41 9.8 0.5 1.4 1 0 0 1 1 1 0 Met-zincin DUF4407 PF14362.6 OAJ18681.1 - 0.5 9.7 9.8 0.58 9.5 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDK PF00334.19 OAJ18682.1 - 0.0006 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.19 OAJ18715.1 - 1.7e-29 102.5 0.0 2.1e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Tcf25 PF04910.14 OAJ18716.1 - 5.7e-89 298.6 0.0 7.2e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TetR_C_28 PF17937.1 OAJ18716.1 - 0.017 15.6 1.1 6.9 7.2 0.2 3.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain XPC-binding PF09280.11 OAJ18716.1 - 0.23 11.2 1.3 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 XPC-binding domain YL1 PF05764.13 OAJ18716.1 - 1.8 8.6 25.0 0.76 9.8 10.0 2.4 2 0 0 2 2 2 0 YL1 nuclear protein NARP1 PF12569.8 OAJ18716.1 - 8.1 5.2 7.1 24 3.7 5.4 2.4 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 6PF2K PF01591.18 OAJ18717.1 - 2.7e-69 232.9 0.0 3.9e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAJ18717.1 - 1.6e-33 116.1 0.0 4.7e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAJ18717.1 - 1.6e-08 34.8 0.0 3.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAJ18717.1 - 0.0055 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain GBP PF02263.19 OAJ18717.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Spt20 PF12090.8 OAJ18718.1 - 2e-30 106.2 0.0 2e-30 106.2 0.0 7.5 4 4 0 4 4 4 1 Spt20 family TFIIF_alpha PF05793.12 OAJ18718.1 - 1.4 7.4 60.1 0.0083 14.8 43.7 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA PF00004.29 OAJ18719.1 - 1.6e-13 51.2 0.0 3.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ18719.1 - 1.3e-05 25.2 0.0 0.00097 19.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 OAJ18719.1 - 8.3e-05 22.4 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAJ18719.1 - 0.00015 21.8 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAJ18719.1 - 0.00025 21.2 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAJ18719.1 - 0.00027 21.4 1.0 0.002 18.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ18719.1 - 0.019 15.3 0.0 0.068 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAJ18719.1 - 0.019 15.2 0.1 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 OAJ18719.1 - 0.022 15.1 0.1 0.068 13.5 0.1 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_30 PF13604.6 OAJ18719.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAJ18719.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OAJ18719.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 OAJ18719.1 - 0.072 13.0 0.1 0.19 11.6 0.1 1.7 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.6 OAJ18719.1 - 0.081 13.1 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ18719.1 - 0.084 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 OAJ18719.1 - 0.099 13.0 0.2 0.3 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ18719.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 OAJ18719.1 - 0.27 11.1 0.1 0.58 10.0 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase Mito_carr PF00153.27 OAJ18720.1 - 2.8e-29 100.9 5.2 4.2e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Copper-fist PF00649.18 OAJ18721.1 - 6.1e-15 54.4 0.9 1.6e-14 53.1 0.9 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Spore_GerAC PF05504.11 OAJ18724.1 - 0.048 13.9 1.8 0.081 13.1 1.8 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Spc7 PF08317.11 OAJ18724.1 - 0.078 11.8 17.4 0.058 12.3 15.9 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAJ18724.1 - 0.18 11.9 14.0 0.3 11.2 14.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2570 PF10828.8 OAJ18724.1 - 6.4 6.6 13.5 3.9 7.3 9.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) DivIC PF04977.15 OAJ18724.1 - 8.3 6.3 17.6 3.4 7.5 4.9 2.7 1 1 1 2 2 2 0 Septum formation initiator Vps53_N PF04100.12 OAJ18726.1 - 5e-86 289.0 3.3 9.2e-86 288.2 3.3 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 OAJ18726.1 - 0.00018 21.5 0.0 0.0013 18.7 0.0 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 OAJ18726.1 - 0.0029 16.9 5.9 0.006 15.9 5.9 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RecG_N PF17190.4 OAJ18726.1 - 0.086 13.6 0.7 0.3 11.9 0.7 2.0 1 0 0 1 1 1 0 RecG N-terminal helical domain Sec5 PF15469.6 OAJ18726.1 - 0.15 11.8 2.9 0.35 10.6 2.9 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 Fib_alpha PF08702.10 OAJ18726.1 - 4.4 7.5 5.3 17 5.6 4.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OAJ18726.1 - 4.6 7.3 9.4 13 5.9 7.6 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAT PF02184.16 OAJ18727.1 - 5.2e-17 61.5 56.7 3.2e-09 36.6 0.6 14.1 16 0 0 16 16 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OAJ18727.1 - 9.2e-15 54.1 34.9 0.0021 18.8 0.1 11.3 5 2 8 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ18727.1 - 1.6e-12 47.7 1.3 0.0011 19.5 0.0 6.2 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18727.1 - 1e-07 31.5 4.7 3.5 8.0 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18727.1 - 3.2e-06 26.9 0.7 0.55 10.6 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18727.1 - 0.0025 17.6 1.0 86 3.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ18727.1 - 0.0052 17.1 0.2 0.46 11.0 0.0 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OAJ18727.1 - 0.024 14.7 7.2 0.52 10.4 0.3 4.6 3 1 1 4 4 4 0 U3 small nucleolar RNA-associated protein 6 ECSIT PF06239.11 OAJ18727.1 - 0.034 13.3 2.6 0.5 9.5 0.4 2.6 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 OAJ18727.1 - 0.037 14.1 6.2 23 5.3 0.0 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ18727.1 - 0.13 11.4 0.0 0.13 11.4 0.0 5.6 2 2 4 6 6 6 0 Tetratricopeptide repeat PcfK PF14058.6 OAJ18727.1 - 0.34 11.2 3.1 0.96 9.7 0.8 2.6 2 0 0 2 2 2 0 PcfK-like protein Mad3_BUB1_I PF08311.12 OAJ18727.1 - 0.4 10.7 16.6 5.3 7.0 0.1 6.4 6 2 0 6 6 6 0 Mad3/BUB1 homology region 1 NOA36 PF06524.12 OAJ18727.1 - 9.7 5.4 8.7 4.5 6.5 2.5 2.2 2 0 0 2 2 2 0 NOA36 protein BSD PF03909.17 OAJ18727.1 - 9.8 6.3 7.1 0.65 10.0 0.2 2.6 3 0 0 3 3 3 0 BSD domain Acetyltransf_1 PF00583.25 OAJ18728.1 - 4.2e-05 23.8 0.0 6.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GTP_EFTU PF00009.27 OAJ18754.1 - 5.6e-33 114.1 0.0 2.7e-32 111.9 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAJ18754.1 - 9.1e-17 61.1 0.2 3e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAJ18754.1 - 9.3e-11 42.0 11.1 1.3e-09 38.3 0.2 4.0 3 1 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ18754.1 - 7.1e-07 29.3 0.1 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ18754.1 - 0.00024 21.3 0.0 0.00068 19.8 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 OAJ18754.1 - 0.0055 16.6 0.2 0.017 15.0 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.6 OAJ18754.1 - 0.12 12.7 0.3 1 9.6 0.3 2.4 1 1 0 1 1 1 0 AAA domain PapB PF03333.13 OAJ18754.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein Trm112p PF03966.16 OAJ18755.1 - 8.6e-17 61.5 0.1 1.3e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zf-RING_7 PF02591.15 OAJ18755.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain DHHC PF01529.20 OAJ18756.1 - 1.1e-11 44.9 3.7 1.1e-11 44.9 3.7 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3290 PF11694.8 OAJ18756.1 - 0.31 11.0 2.9 0.67 9.9 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) tRNA-synt_2b PF00587.25 OAJ18757.1 - 1.6e-07 31.5 0.0 2.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Abhydrolase_3 PF07859.13 OAJ18758.1 - 1.5e-29 103.4 0.0 4.3e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ18758.1 - 0.00016 20.7 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAJ18758.1 - 0.11 12.0 0.0 8.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GYF PF02213.16 OAJ18759.1 - 6.9e-19 67.2 1.6 1.5e-18 66.2 1.6 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAJ18759.1 - 5.3e-06 26.1 0.2 1.4e-05 24.8 0.2 1.8 1 0 0 1 1 1 1 GYF domain 2 Xpo1 PF08389.12 OAJ18760.1 - 3.8e-26 91.9 0.0 3e-24 85.8 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 OAJ18760.1 - 8.6e-08 32.0 0.1 2.9e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 OAJ18760.1 - 0.0012 19.0 0.0 0.0086 16.2 0.0 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 OAJ18760.1 - 0.0017 18.5 0.1 0.42 10.7 0.0 3.1 2 1 1 3 3 3 1 Parkin co-regulated protein RasGEF_N_2 PF14663.6 OAJ18760.1 - 0.013 15.9 0.2 0.9 10.0 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2489 PF10675.9 OAJ18760.1 - 0.023 14.6 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) HEAT PF02985.22 OAJ18760.1 - 0.049 13.9 2.5 0.3 11.5 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat 2_5_RNA_ligase2 PF13563.6 OAJ18760.1 - 0.074 13.0 0.9 0.25 11.3 0.1 2.4 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily TetR_C_22 PF17928.1 OAJ18760.1 - 0.089 13.1 0.8 9.9 6.5 0.0 3.8 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain FerA PF08165.11 OAJ18760.1 - 0.1 12.6 0.1 0.47 10.4 0.1 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain HEAT_EZ PF13513.6 OAJ18760.1 - 2 9.0 10.9 4.2 8.0 0.0 5.7 5 1 1 6 6 6 0 HEAT-like repeat Indigoidine_A PF04227.12 OAJ18761.1 - 2.2e-109 365.3 1.5 4e-109 364.5 1.5 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAJ18761.1 - 1.5e-18 67.2 1.9 8.9e-10 38.4 0.2 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Myb_DNA-binding PF00249.31 OAJ18762.1 - 7.2e-20 70.9 6.8 5.3e-15 55.3 3.8 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ18762.1 - 6.1e-14 52.0 7.5 1.1e-09 38.4 0.8 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ18762.1 - 9.5e-05 22.7 6.8 0.028 14.8 0.0 3.2 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ18762.1 - 0.021 15.0 0.2 1.7 8.9 0.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 ANAPC4 PF12896.7 OAJ18762.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Cwf_Cwc_15 PF04889.12 OAJ18762.1 - 3 7.5 36.4 2.1 8.0 6.3 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_ligase_A_M PF01068.21 OAJ18763.1 - 1.4e-38 132.6 0.0 8.7e-26 90.8 0.0 3.8 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ18763.1 - 1.7e-30 106.6 0.0 3.2e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAJ18763.1 - 3.2e-17 63.0 0.2 1.2e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DUF2433 PF10360.9 OAJ18764.1 - 4.3e-45 152.8 0.1 6.9e-45 152.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 OAJ18764.1 - 0.076 13.2 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF155 PF02582.14 OAJ18791.1 - 2.1e-49 168.0 0.0 3.4e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 VHS PF00790.19 OAJ18792.1 - 2e-35 121.7 1.7 2.8e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 OAJ18792.1 - 5.3e-16 58.5 9.1 1e-15 57.6 9.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OAJ18792.1 - 6.9e-05 23.1 2.2 0.00014 22.1 2.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.20 OAJ18792.1 - 0.00073 19.3 8.8 0.038 13.9 1.9 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF3602 PF12223.8 OAJ18792.1 - 0.0015 19.1 0.3 0.0092 16.6 0.3 2.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) zf-RING_5 PF14634.6 OAJ18792.1 - 1.1 9.3 11.5 1.8 8.6 11.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain OAD_gamma PF04277.13 OAJ18792.1 - 1.8 9.2 3.4 3 8.5 0.0 3.1 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DnaJ PF00226.31 OAJ18793.1 - 5.5e-23 80.9 0.2 9.7e-23 80.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 OAJ18793.1 - 1.6e-19 70.1 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Sporozoite_P67 PF05642.11 OAJ18794.1 - 0.54 8.3 3.0 0.79 7.7 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.8 OAJ18794.1 - 2.2 7.4 6.7 3.3 6.8 6.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cpn60_TCP1 PF00118.24 OAJ18795.1 - 3.1e-159 530.7 4.8 3.5e-159 530.5 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 OAJ18795.1 - 0.028 13.6 0.4 0.24 10.6 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase COLFI PF01410.18 OAJ18796.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Tmemb_14 PF03647.13 OAJ18797.1 - 6e-16 59.0 10.1 6.9e-16 58.8 10.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Ig_mannosidase PF17753.1 OAJ18798.1 - 1e-15 57.2 0.2 5.7e-15 54.8 0.0 2.4 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 OAJ18798.1 - 3e-09 37.4 0.1 1.7e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAJ18798.1 - 5e-08 33.6 0.1 1.1e-07 32.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Endomucin PF07010.12 OAJ18799.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.4 3 1 1 4 4 4 0 Endomucin AMP-binding PF00501.28 OAJ18800.1 - 7.3e-50 169.8 0.0 1.3e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAJ18800.1 - 2.2e-11 44.0 0.4 4.9e-11 42.8 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 OAJ18800.1 - 1.4e-10 40.5 1.8 0.00014 21.5 0.1 5.9 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) GH3 PF03321.13 OAJ18800.1 - 0.044 12.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter AMP-binding_C PF13193.6 OAJ18800.1 - 0.067 14.2 4.6 0.13 13.2 0.0 3.2 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 OAJ18800.1 - 0.31 10.8 10.0 2.4 8.0 0.1 4.6 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase CBFB_NFYA PF02045.15 OAJ18833.1 - 3.5e-18 65.9 18.8 1.8e-11 44.5 5.1 3.0 2 2 0 2 2 2 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GHMP_kinases_C PF08544.13 OAJ18833.1 - 0.00037 20.8 2.2 0.69 10.3 0.1 2.3 2 0 0 2 2 2 2 GHMP kinases C terminal Atrophin-1 PF03154.15 OAJ18833.1 - 0.61 8.3 7.9 0.95 7.7 7.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family PHD PF00628.29 OAJ18835.1 - 4.5e-05 23.3 8.7 4.5e-05 23.3 8.7 2.5 2 1 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 OAJ18835.1 - 0.0084 16.3 1.2 0.0084 16.3 1.2 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain FANCL_C PF11793.8 OAJ18835.1 - 0.0087 16.2 1.2 0.024 14.8 1.2 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain PHD_Oberon PF07227.11 OAJ18835.1 - 0.01 15.7 2.0 0.01 15.7 2.0 2.0 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Zf_RING PF16744.5 OAJ18835.1 - 0.47 10.6 5.3 3.8 7.7 5.3 2.5 1 1 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 OAJ18835.1 - 2.4 8.1 7.8 0.71 9.8 0.3 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_S10 PF00450.22 OAJ18837.1 - 2e-98 330.6 0.0 2.5e-98 330.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4148 PF13663.6 OAJ18837.1 - 0.4 10.9 3.4 0.77 10.0 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) NEMP PF10225.9 OAJ18838.1 - 0.0045 16.7 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 NEMP family UL42 PF17638.2 OAJ18838.1 - 6.9 6.7 7.5 1.6 8.7 0.9 2.8 2 1 1 3 3 3 0 HCMV UL42 TraV PF09676.10 OAJ18840.1 - 9.6 7.2 9.6 4.8 8.2 3.6 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) UCH PF00443.29 OAJ18841.1 - 0.03 13.8 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ADH_zinc_N_2 PF13602.6 OAJ18842.1 - 1.2e-18 68.5 0.0 4.1e-18 66.7 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ18842.1 - 3.8e-14 52.8 1.1 9.6e-14 51.5 0.5 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ18842.1 - 1.8e-10 40.7 0.2 2.3e-07 30.6 0.0 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ18842.1 - 0.0016 18.4 0.0 0.009 15.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 OAJ18842.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PALP PF00291.25 OAJ18842.1 - 0.03 13.8 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PIN_4 PF13638.6 OAJ18844.1 - 6.4e-07 29.7 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 PIN domain UCH PF00443.29 OAJ18845.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FAD_binding_3 PF01494.19 OAJ18880.1 - 1.9e-17 63.5 0.0 3.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ18880.1 - 5.7e-06 25.8 0.0 0.0099 15.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ18880.1 - 0.0049 17.1 0.1 0.0099 16.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAJ18880.1 - 0.012 14.7 0.0 0.043 12.9 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.16 OAJ18880.1 - 0.021 14.5 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAJ18880.1 - 0.076 12.3 0.2 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ18880.1 - 0.11 12.1 0.1 3.3 7.2 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ18880.1 - 0.15 12.0 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 OAJ18881.1 - 5.2e-46 157.4 1.6 6.1e-44 150.6 0.5 2.7 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ18881.1 - 4.7e-29 101.8 0.1 8.3e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ18881.1 - 3.7e-06 26.3 0.3 0.00054 19.2 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ18881.1 - 7.5e-06 26.1 0.2 2.1e-05 24.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAJ18881.1 - 1.4e-05 24.3 0.1 2.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAJ18881.1 - 0.00038 20.2 0.7 0.00038 20.2 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ18881.1 - 0.0007 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ18881.1 - 0.0011 18.3 0.3 0.0024 17.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ18881.1 - 0.0042 16.4 1.3 0.0058 15.9 0.2 1.7 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 OAJ18881.1 - 0.03 14.6 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAJ18881.1 - 0.04 13.2 0.1 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ18881.1 - 0.054 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAJ18881.1 - 0.091 11.4 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAJ18881.1 - 0.16 12.6 0.1 0.3 11.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S25 PF03297.15 OAJ18882.1 - 1.3e-37 128.0 2.3 1.7e-37 127.7 2.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 OAJ18882.1 - 0.02 14.5 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 OAJ18882.1 - 0.033 14.1 0.2 0.064 13.2 0.1 1.5 2 0 0 2 2 2 0 MarR family CoA_trans PF01144.23 OAJ18882.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.5 1 1 1 2 2 2 0 Coenzyme A transferase S10_plectin PF03501.15 OAJ18883.1 - 8.2e-40 134.8 0.1 1e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sulfotransfer_4 PF17784.1 OAJ18884.1 - 7e-47 160.0 0.0 1e-46 159.5 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAJ18884.1 - 6.2e-05 23.5 0.1 0.0024 18.3 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family CBM_5_12 PF02839.14 OAJ18884.1 - 0.024 15.2 0.3 0.076 13.6 0.3 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain Enolase_like_N PF18374.1 OAJ18884.1 - 0.048 13.1 2.5 0.49 9.8 0.1 2.9 3 0 0 3 3 3 0 Enolase N-terminal domain-like F_bP_aldolase PF01116.20 OAJ18885.1 - 2.4e-78 263.4 0.7 1.3e-49 169.1 0.2 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-II DER1 PF04511.15 OAJ18886.1 - 4e-31 108.4 1.0 5.3e-31 108.0 1.0 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 OAJ18886.1 - 0.1 12.6 3.0 0.17 11.9 3.0 1.3 1 0 0 1 1 1 0 Rhomboid family Nup88 PF10168.9 OAJ18887.1 - 2e-13 49.1 1.7 0.00036 18.5 0.0 5.0 5 0 0 5 5 5 4 Nuclear pore component ZapB PF06005.12 OAJ18887.1 - 4.2 7.9 6.0 4.6 7.8 0.1 3.2 3 0 0 3 3 3 0 Cell division protein ZapB TolA_bind_tri PF16331.5 OAJ18887.1 - 7.6 6.7 15.2 9.6 6.4 0.2 4.2 4 0 0 4 4 4 0 TolA binding protein trimerisation SKA2 PF16740.5 OAJ18887.1 - 7.7 6.4 9.6 7.1 6.5 0.1 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Dickkopf_N PF04706.12 OAJ18888.1 - 0.12 12.9 26.0 0.039 14.4 11.1 3.6 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region SUR7 PF06687.12 OAJ18888.1 - 0.17 11.5 0.6 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 SUR7/PalI family V-ATPase_C PF03223.15 OAJ18889.1 - 1.1e-129 433.0 4.1 1.3e-129 432.9 4.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C YscK PF06578.12 OAJ18889.1 - 0.0046 16.5 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 YOP proteins translocation protein K (YscK) DUF3818 PF12825.7 OAJ18890.1 - 1.8e-51 175.2 0.0 2.7e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ18890.1 - 7.9e-23 80.9 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 PX-associated zf-CCCH PF00642.24 OAJ18891.1 - 3.3e-09 36.4 2.7 6.2e-09 35.5 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 OAJ18891.1 - 1.4e-07 31.3 5.4 2.3e-07 30.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ18891.1 - 2.5e-06 27.4 8.7 4.7e-06 26.5 8.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ18891.1 - 4.6e-06 26.5 8.8 7.5e-06 25.8 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 OAJ18891.1 - 2e-05 24.5 4.4 3.9e-05 23.6 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 OAJ18891.1 - 2.9e-05 23.8 8.2 5.2e-05 23.0 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ18891.1 - 3e-05 23.8 8.5 5.2e-05 23.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ18891.1 - 8.8e-05 22.8 6.7 0.00016 21.9 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ18891.1 - 0.00013 22.0 7.6 0.00027 21.0 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OAJ18891.1 - 0.00055 20.0 3.3 0.0013 18.8 3.3 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 OAJ18891.1 - 0.0016 18.2 2.9 0.0039 17.0 2.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-Nse PF11789.8 OAJ18891.1 - 0.037 13.9 2.6 0.067 13.0 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.9 OAJ18891.1 - 0.07 13.7 0.2 0.19 12.3 0.2 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Prok-RING_4 PF14447.6 OAJ18891.1 - 0.075 12.9 5.8 0.14 12.0 5.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C1_2 PF03107.16 OAJ18891.1 - 0.62 10.4 5.0 2.7 8.4 1.0 2.5 1 1 1 2 2 2 0 C1 domain zf-rbx1 PF12678.7 OAJ18891.1 - 2.3 8.6 5.3 7.1 7.0 5.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Aldedh PF00171.22 OAJ18892.1 - 1.3e-154 515.2 0.0 1.4e-154 515.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Thx PF17070.5 OAJ18892.1 - 0.0014 18.7 0.5 0.0014 18.7 0.5 1.7 2 0 0 2 2 2 1 30S ribosomal protein Thx LuxC PF05893.14 OAJ18892.1 - 0.0028 16.7 0.1 0.0045 16.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pkinase PF00069.25 OAJ18922.1 - 2.5e-69 233.6 0.0 5.1e-69 232.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18922.1 - 1.6e-29 103.0 0.0 1.6e-28 99.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ18922.1 - 0.00012 21.5 0.8 2.6 7.3 0.1 3.2 3 0 0 3 3 3 3 Kinase-like RIO1 PF01163.22 OAJ18922.1 - 0.00035 20.2 0.6 0.00066 19.3 0.6 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OAJ18922.1 - 0.0081 15.0 0.1 0.019 13.8 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ18922.1 - 0.0096 15.9 3.3 0.52 10.2 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family F-box-like PF12937.7 OAJ18924.1 - 5.9e-10 38.9 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 OAJ18924.1 - 2.4e-05 25.0 0.0 2.4 9.2 0.0 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat F-box PF00646.33 OAJ18924.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 OAJ18924.1 - 0.00067 19.4 10.1 0.17 11.9 0.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif F-box_4 PF15966.5 OAJ18924.1 - 0.00078 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 F-box Ribosomal_L29e PF01779.17 OAJ18926.1 - 3.4e-06 27.3 12.8 3.4e-06 27.3 12.8 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_L11 PF00298.19 OAJ18926.1 - 0.036 14.6 1.0 0.044 14.3 1.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Noc2 PF03715.13 OAJ18927.1 - 1.3e-108 362.8 0.3 2.7e-108 361.7 0.0 1.6 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 OAJ18927.1 - 0.13 10.5 31.0 1 7.5 0.1 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 OAJ18927.1 - 0.46 9.8 27.8 0.88 8.8 27.8 1.4 1 0 0 1 1 1 0 BUD22 RrnaAD PF00398.20 OAJ18928.1 - 5.7e-59 199.4 0.0 7.6e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAJ18928.1 - 1.2e-07 32.3 0.0 2.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ18928.1 - 3e-05 24.6 0.0 5.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ18928.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 OAJ18928.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 OAJ18928.1 - 0.00028 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OAJ18928.1 - 0.00047 20.0 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 OAJ18928.1 - 0.00087 20.0 0.0 0.0016 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ18928.1 - 0.0048 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ18928.1 - 0.0059 16.4 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAJ18928.1 - 0.016 14.9 0.0 0.086 12.5 0.0 1.9 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.18 OAJ18928.1 - 0.046 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_28 PF02636.17 OAJ18928.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 OAJ18928.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-C2H2 PF00096.26 OAJ18929.1 - 5e-09 36.1 7.3 0.00044 20.6 3.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ18929.1 - 9.6e-08 32.1 9.6 2.3e-06 27.8 1.7 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ18929.1 - 6.7e-07 29.6 6.9 0.00069 20.2 3.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ18929.1 - 0.00032 20.9 4.1 0.01 16.1 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 OAJ18929.1 - 0.028 15.1 2.1 0.044 14.5 2.1 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.7 OAJ18929.1 - 0.038 14.4 1.8 0.062 13.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Spt46 PF17734.1 OAJ18929.1 - 0.039 13.8 0.2 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-Di19 PF05605.12 OAJ18929.1 - 0.097 13.0 1.6 0.17 12.2 1.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OAJ18929.1 - 0.76 9.9 4.6 0.5 10.4 2.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger CUE PF02845.16 OAJ18930.1 - 4.4e-09 35.9 0.0 8.4e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 OAJ18930.1 - 0.04 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) COX6B PF02297.17 OAJ18962.1 - 6.6e-23 80.7 0.2 8.3e-23 80.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OAJ18962.1 - 0.3 11.4 2.5 12 6.3 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Glyco_hydro_9 PF00759.19 OAJ18963.1 - 9.2e-97 325.1 6.1 1.1e-96 324.8 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 T2SSM PF04612.12 OAJ18963.1 - 2.7 8.0 7.4 0.34 11.0 0.7 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M GspL_C PF12693.7 OAJ18963.1 - 4.6 7.1 10.0 0.3 10.9 2.3 2.7 3 0 0 3 3 3 0 GspL periplasmic domain CENP-F_leu_zip PF10473.9 OAJ18964.1 - 0.0027 17.7 15.5 0.0027 17.7 15.5 3.8 2 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OAJ18964.1 - 0.2 11.0 25.0 0.25 10.7 1.7 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding YgaB PF14182.6 OAJ18964.1 - 1.6 9.2 6.6 0.2 12.0 1.3 2.3 2 0 0 2 2 2 0 YgaB-like protein DDE_Tnp_4 PF13359.6 OAJ18965.1 - 2.6e-17 63.0 0.0 3.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ18965.1 - 0.00046 19.9 0.0 0.0011 18.6 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ18965.1 - 0.009 15.6 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 OAJ18965.1 - 0.014 15.7 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 OAJ18966.1 - 1.1e-21 77.6 4.8 6e-14 52.8 0.2 2.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ18966.1 - 7.9e-09 35.8 5.4 0.00043 20.6 0.6 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Gag_p10 PF02337.17 OAJ18966.1 - 0.0011 18.8 0.9 1.9 8.5 0.1 2.4 2 0 0 2 2 2 2 Retroviral GAG p10 protein EF-hand_14 PF17959.1 OAJ18966.1 - 0.011 16.1 0.0 9.7 6.6 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain PSK PF06404.12 OAJ18966.1 - 0.015 16.2 0.2 17 6.5 0.0 2.9 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) HHH_2 PF12826.7 OAJ18966.1 - 0.071 13.2 0.1 23 5.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif TilS_C PF11734.8 OAJ18966.1 - 0.14 11.6 0.8 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 TilS substrate C-terminal domain DUF2277 PF10041.9 OAJ18966.1 - 0.34 11.3 1.9 39 4.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) adh_short PF00106.25 OAJ19000.1 - 9.5e-25 87.2 0.0 6.1e-16 58.5 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ19000.1 - 4.6e-14 52.5 0.0 1.4e-12 47.7 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ19000.1 - 5.3e-08 32.6 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ19000.1 - 0.00029 20.8 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAJ19000.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) MBG PF17883.1 OAJ19000.1 - 0.04 14.5 0.1 0.074 13.7 0.0 1.4 1 1 0 1 1 1 0 MBG domain MoCF_biosynth PF00994.24 OAJ19001.1 - 2.3e-33 114.9 0.0 4.2e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAP1 PF08601.10 OAJ19001.1 - 0.044 13.5 1.4 0.066 12.9 1.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Erp_C PF06780.11 OAJ19001.1 - 0.16 12.0 0.2 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus ELO PF01151.18 OAJ19002.1 - 1.8e-54 184.9 6.8 2.3e-54 184.6 6.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LPD24 PF18839.1 OAJ19002.1 - 0.39 11.0 2.1 0.5 10.7 0.7 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 MaoC_dehydratas PF01575.19 OAJ19003.1 - 1.2e-23 82.9 0.0 2.9e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAJ19003.1 - 4.6e-06 26.8 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Antimicrobial_5 PF08026.11 OAJ19003.1 - 2 8.6 7.8 9.9 6.3 2.4 3.2 3 0 0 3 3 3 0 Bee antimicrobial peptide PepSY_TM PF03929.16 OAJ19004.1 - 0.46 10.1 7.9 0.72 9.5 7.1 1.6 1 1 0 1 1 1 0 PepSY-associated TM region DUF1072 PF06380.11 OAJ19004.1 - 2.4 8.1 6.6 2.5 8.0 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) GSAP-16 PF14959.6 OAJ19005.1 - 0.24 11.3 0.1 0.47 10.3 0.1 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term S4 PF01479.25 OAJ19006.1 - 5.2e-11 42.1 1.3 5.2e-11 42.1 1.3 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 OAJ19006.1 - 2e-06 28.6 0.2 5.2e-06 27.3 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 OAJ19007.1 - 2.5e-45 152.5 1.7 2.5e-45 152.5 1.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e TRAP-gamma PF07074.12 OAJ19007.1 - 0.12 11.9 0.4 0.16 11.5 0.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Alanine_zipper PF11839.8 OAJ19008.1 - 0.0015 18.9 5.1 0.0015 18.9 5.1 3.8 4 0 0 4 4 4 1 Alanine-zipper, major outer membrane lipoprotein CENP-F_leu_zip PF10473.9 OAJ19008.1 - 0.033 14.2 12.3 0.51 10.4 7.8 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BCNT PF07572.12 OAJ19008.1 - 0.067 13.3 0.9 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Bucentaur or craniofacial development PRMT5_C PF17286.2 OAJ19008.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Sec2p PF06428.11 OAJ19008.1 - 0.17 11.9 6.6 2.2 8.3 0.8 3.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Coprogen_oxidas PF01218.18 OAJ19009.1 - 4.7e-124 412.9 0.0 1.2e-123 411.6 0.0 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Vfa1 PF08432.10 OAJ19010.1 - 3.6e-33 115.4 0.1 8.2e-33 114.2 0.1 1.5 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PV-1 PF06637.11 OAJ19010.1 - 0.047 12.5 2.9 0.069 12.0 2.9 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) SKA1 PF07160.12 OAJ19010.1 - 0.14 12.0 1.6 0.19 11.5 1.6 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF5427 PF10310.9 OAJ19010.1 - 0.18 10.7 4.5 0.23 10.4 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NTF2 PF02136.20 OAJ19011.1 - 0.11 13.1 0.0 5.3 7.6 0.0 3.0 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Sacchrp_dh_NADP PF03435.18 OAJ19012.1 - 6.4e-16 58.8 0.1 1e-15 58.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAJ19012.1 - 1e-06 28.4 0.1 1.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ19012.1 - 1.8e-06 27.9 0.2 4.3e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAJ19012.1 - 0.00018 21.1 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAJ19012.1 - 0.0004 19.9 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ19012.1 - 0.0018 17.3 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ19012.1 - 0.004 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 OAJ19012.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 OAJ19012.1 - 0.023 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 OAJ19012.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 OAJ19012.1 - 0.072 12.2 0.3 0.41 9.8 0.1 2.3 2 1 0 2 2 2 0 Male sterility protein RNA_pol_Rpc4 PF05132.14 OAJ19013.1 - 4.8 7.6 12.6 5.7 7.3 12.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4834 PF16118.5 OAJ19013.1 - 5 8.2 8.7 5.7 8.0 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Phospho_p8 PF10195.9 OAJ19013.1 - 9 6.9 12.2 1.4e+02 3.0 12.2 2.1 1 1 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Coilin_N PF15862.5 OAJ19013.1 - 9.1 6.1 13.9 11 5.8 13.9 1.2 1 0 0 1 1 1 0 Coilin N-terminus TRAPPC-Trs85 PF12739.7 OAJ19014.1 - 3.4e-101 339.2 0.0 4.9e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit WD40 PF00400.32 OAJ19015.1 - 2.3e-10 40.9 14.0 0.012 16.4 0.0 6.7 5 2 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19015.1 - 0.00045 20.5 0.0 8.5 6.7 0.0 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NUDIX PF00293.28 OAJ19049.1 - 1.7e-11 44.2 0.0 3.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NDK PF00334.19 OAJ19051.1 - 3.3e-50 169.6 0.0 4.3e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase RCC1 PF00415.18 OAJ19052.1 - 1.2e-10 41.9 1.1 0.19 12.4 0.0 6.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ19052.1 - 0.00063 19.5 14.3 0.14 12.0 1.0 5.4 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat TRAPPC9-Trs120 PF08626.11 OAJ19053.1 - 3.6e-156 521.5 0.0 7e-155 517.3 0.0 2.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit His_Phos_2 PF00328.22 OAJ19055.1 - 2.4e-17 63.4 0.0 4.6e-17 62.4 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NepR PF18557.1 OAJ19055.1 - 0.33 10.6 1.5 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Anti-sigma factor NepR Tim17 PF02466.19 OAJ19056.1 - 7.4e-09 36.0 1.3 8.7e-09 35.8 0.4 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MRP-S33 PF08293.11 OAJ19057.1 - 5e-20 71.5 0.4 1.9e-19 69.7 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Pkinase PF00069.25 OAJ19058.1 - 1.6e-71 240.8 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19058.1 - 1.9e-33 115.9 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ19058.1 - 0.00051 19.1 0.0 0.00071 18.6 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ19058.1 - 0.00061 19.8 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ19058.1 - 0.00085 18.7 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OAJ19058.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 OAJ19058.1 - 0.066 12.8 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ADH_zinc_N PF00107.26 OAJ19059.1 - 7.2e-06 26.0 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ19059.1 - 0.0083 17.2 0.0 0.019 16.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Catalase PF00199.19 OAJ19060.1 - 5.1e-154 513.0 2.0 1.4e-137 458.9 0.6 2.1 2 0 0 2 2 2 2 Catalase Catalase-rel PF06628.12 OAJ19060.1 - 1.1e-13 51.2 0.2 3e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Disaggr_repeat PF06848.11 OAJ19060.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Disaggregatase related repeat Pkinase PF00069.25 OAJ19061.1 - 7.1e-73 245.2 0.0 8e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19061.1 - 1.1e-31 110.1 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ19061.1 - 6e-05 22.5 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ19061.1 - 0.00048 19.2 0.1 0.0007 18.6 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ19061.1 - 0.00091 19.2 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ19061.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OAJ19061.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fez1 PF06818.15 OAJ19087.1 - 0.32 11.4 9.0 0.46 10.9 8.5 1.4 1 1 0 1 1 1 0 Fez1 DivIVA PF05103.13 OAJ19087.1 - 0.47 10.5 8.4 0.83 9.7 8.4 1.3 1 0 0 1 1 1 0 DivIVA protein Seryl_tRNA_N PF02403.22 OAJ19087.1 - 0.96 9.7 12.4 3.5 7.9 11.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OAJ19087.1 - 1.1 9.1 11.9 0.75 9.6 2.5 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 OAJ19087.1 - 1.4 8.2 11.9 2.9 7.1 11.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 OAJ19087.1 - 1.8 8.6 10.2 5.3 7.1 10.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5320 PF17253.2 OAJ19087.1 - 2.5 9.2 5.3 15 6.7 0.5 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Phage_GP20 PF06810.11 OAJ19087.1 - 2.8 7.7 12.7 5.6 6.8 5.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4140 PF13600.6 OAJ19087.1 - 4.2 7.9 11.6 6.2 7.3 1.9 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 OAJ19087.1 - 4.4 7.4 17.2 0.15 12.1 4.6 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Dimer_Tnp_hAT PF05699.14 OAJ19088.1 - 5.1e-15 55.0 0.4 1e-14 54.1 0.4 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ19088.1 - 0.00045 20.5 0.0 0.0012 19.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) HAUS6_N PF14661.6 OAJ19088.1 - 0.0052 16.4 0.0 0.025 14.2 0.0 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Pkinase PF00069.25 OAJ19089.1 - 1.1e-37 129.9 0.0 1.4e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19089.1 - 1.5e-18 67.0 0.0 2.4e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ19089.1 - 3e-07 30.1 0.1 4.4e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Fuseless PF15993.5 OAJ19089.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Fuseless DAO PF01266.24 OAJ19115.1 - 3.6e-53 181.4 2.3 4.1e-53 181.2 2.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ19115.1 - 3.3e-06 27.6 0.2 0.026 15.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ19115.1 - 5.2e-05 22.6 0.2 0.0041 16.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ19115.1 - 0.00045 20.4 1.5 0.0011 19.2 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ19115.1 - 0.0043 16.3 0.1 0.011 15.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 OAJ19115.1 - 0.035 13.4 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAJ19115.1 - 0.052 12.4 0.3 0.52 9.1 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 OAJ19115.1 - 0.16 12.2 0.2 0.42 10.9 0.2 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 OAJ19115.1 - 0.22 11.5 0.7 0.43 10.6 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Aminotran_3 PF00202.21 OAJ19116.1 - 5.7e-90 301.9 0.0 8.1e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SUZ PF12752.7 OAJ19117.1 - 2.9e-10 40.7 12.3 2.9e-10 40.7 12.3 8.7 9 1 0 9 9 9 1 SUZ domain R3H PF01424.22 OAJ19117.1 - 4.5e-05 23.4 0.1 8.6e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 R3H domain UCH PF00443.29 OAJ19118.1 - 1.4e-38 132.9 0.0 2e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ19118.1 - 0.00014 21.6 0.0 0.29 10.7 0.2 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Adaptin_N PF01602.20 OAJ19119.1 - 1.5e-100 337.2 10.5 2.6e-100 336.5 10.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 OAJ19119.1 - 2.3e-60 202.2 0.0 6.6e-60 200.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 OAJ19119.1 - 4.1e-60 201.7 0.1 9.5e-60 200.6 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 OAJ19119.1 - 1.8e-12 47.6 8.2 3.9e-08 33.5 0.1 3.8 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ19119.1 - 5.4e-10 39.5 7.4 0.017 15.5 0.0 5.9 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.22 OAJ19119.1 - 3.6e-07 29.9 0.2 0.046 14.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 OAJ19119.1 - 0.0031 17.6 0.2 0.051 13.7 0.0 2.8 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform ParcG PF10274.9 OAJ19119.1 - 0.024 14.8 0.8 0.99 9.5 0.0 2.7 2 1 0 2 2 2 0 Parkin co-regulated protein HEAT_EZ PF13513.6 OAJ19119.1 - 0.026 15.0 0.4 6.7 7.3 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat Hairpins PF04877.12 OAJ19119.1 - 0.032 13.9 0.3 0.063 12.9 0.3 1.4 1 0 0 1 1 1 0 HrpZ Arm PF00514.23 OAJ19119.1 - 0.041 14.0 0.5 70 3.7 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF5071 PF16804.5 OAJ19119.1 - 0.11 12.8 1.0 7.5 6.8 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5071) Dabb PF07876.12 OAJ19120.1 - 1.5e-15 57.6 0.1 1.7e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Peptidase_S9 PF00326.21 OAJ19122.1 - 3.7e-49 167.1 0.2 5.7e-49 166.5 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAJ19122.1 - 0.00092 18.8 0.2 0.0018 17.8 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 OAJ19122.1 - 0.0014 18.4 0.4 0.0057 16.3 0.3 2.1 2 1 0 2 2 2 1 Putative esterase AXE1 PF05448.12 OAJ19122.1 - 0.0071 15.1 0.4 0.64 8.6 0.0 2.4 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.12 OAJ19122.1 - 0.021 14.7 1.0 0.063 13.2 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RNA12 PF10443.9 OAJ19124.1 - 1.1e-127 426.5 0.5 1.7e-127 425.9 0.5 1.3 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 OAJ19124.1 - 0.0026 17.7 0.0 0.0065 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea CENP-F_leu_zip PF10473.9 OAJ19124.1 - 0.44 10.6 3.7 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Amino_oxidase PF01593.24 OAJ19125.1 - 1.9e-17 63.7 0.4 3.2e-16 59.7 0.4 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ19125.1 - 2.7e-13 49.9 0.1 6.5e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ19125.1 - 1.7e-05 24.6 1.1 1.7e-05 24.6 1.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ19125.1 - 0.00015 21.0 0.5 0.00015 21.0 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAJ19125.1 - 0.0015 18.5 0.1 0.036 14.0 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ19125.1 - 0.0031 16.8 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ19125.1 - 0.028 15.0 0.3 0.058 14.0 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ19125.1 - 0.19 10.9 0.1 0.38 9.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAJ19125.1 - 0.2 10.9 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ19125.1 - 0.27 9.9 0.2 0.41 9.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAJ19125.1 - 0.8 8.7 1.6 1.2 8.1 1.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.25 OAJ19126.1 - 5.1e-50 169.7 0.5 6.3e-50 169.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ19126.1 - 7.5e-35 120.6 0.2 9.5e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ19126.1 - 1e-14 54.9 0.2 1.3e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OAJ19126.1 - 0.0015 18.0 0.1 0.0035 16.7 0.1 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 OAJ19126.1 - 0.0015 18.0 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAJ19126.1 - 0.0066 15.9 0.1 0.0091 15.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAJ19126.1 - 0.009 15.9 0.5 0.016 15.1 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAJ19126.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAJ19126.1 - 0.057 12.7 0.2 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP_bind_3 PF01171.20 OAJ19127.1 - 1.5e-36 125.9 0.0 3.3e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 PP-loop family MMR_HSR1 PF01926.23 OAJ19127.1 - 4.1e-12 46.2 0.0 9.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ19127.1 - 0.00018 21.5 0.1 0.0082 16.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAJ19127.1 - 0.0014 19.0 2.3 0.025 15.0 0.1 3.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAJ19127.1 - 0.015 15.9 0.3 0.04 14.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 OAJ19127.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 OAJ19127.1 - 0.074 13.3 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NAD_synthase PF02540.17 OAJ19127.1 - 0.14 11.2 0.0 0.58 9.2 0.0 1.8 2 0 0 2 2 2 0 NAD synthase TetR_C_11 PF16859.5 OAJ19127.1 - 0.26 11.6 4.8 14 6.0 0.1 3.9 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L13e PF01294.18 OAJ19127.1 - 0.38 10.6 1.9 0.56 10.0 0.0 2.2 3 0 0 3 3 3 0 Ribosomal protein L13e Ribosomal_L22 PF00237.19 OAJ19155.1 - 5.8e-25 87.5 0.5 5.8e-25 87.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e KAR9 PF08580.10 OAJ19155.1 - 0.041 12.4 0.4 0.045 12.3 0.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPT_ssu-like PF11779.8 OAJ19156.1 - 1.5e-06 27.8 0.4 2.1e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Jiraiya PF15038.6 OAJ19156.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Jiraiya Epiglycanin_C PF14654.6 OAJ19156.1 - 0.034 14.2 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Smim3 PF17307.2 OAJ19156.1 - 0.035 13.6 2.0 0.064 12.8 2.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 PMP1_2 PF08114.11 OAJ19156.1 - 8.1 6.3 7.1 0.29 10.9 0.6 1.8 2 0 0 2 2 2 0 ATPase proteolipid family ADH_zinc_N PF00107.26 OAJ19159.1 - 1.7e-26 92.7 0.2 2.5e-26 92.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ19159.1 - 4.3e-13 50.5 0.0 7.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ19159.1 - 4e-08 33.1 0.0 1.2e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.18 OAJ19159.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 HupF/HypC family APH PF01636.23 OAJ19160.1 - 8.5e-20 71.7 0.2 8.5e-20 71.7 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ19160.1 - 0.04 13.5 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Hva1_TUDOR PF11160.8 OAJ19161.1 - 3.7e-18 65.4 1.3 4.4e-18 65.2 1.3 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain SIR2 PF02146.17 OAJ19162.1 - 9.5e-30 103.8 0.0 3.9e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Sir2 family TIM21 PF08294.11 OAJ19163.1 - 9.4e-13 48.3 0.1 1.8e-11 44.1 0.0 2.6 2 1 0 2 2 2 1 TIM21 Aconitase_2_N PF06434.13 OAJ19164.1 - 0.054 13.1 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Sec8_exocyst PF04048.14 OAJ19166.1 - 0.19 11.6 3.7 0.41 10.5 0.3 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF16 PF01519.16 OAJ19166.1 - 1.2 9.7 11.4 0.45 11.0 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function DUF16 SpoVR PF04293.13 OAJ19167.1 - 5.6 5.5 9.0 8.9 4.9 9.0 1.2 1 0 0 1 1 1 0 SpoVR like protein VSG_B PF13206.6 OAJ19167.1 - 6 6.0 13.9 12 5.0 13.9 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain MFS_1 PF07690.16 OAJ19168.1 - 1.9e-38 132.3 39.7 1.9e-38 132.3 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RabGAP-TBC PF00566.18 OAJ19199.1 - 2.2e-35 122.3 0.1 2.9e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OTCace_N PF02729.21 OAJ19200.1 - 1.5e-46 158.1 0.1 2.5e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 OAJ19200.1 - 8.5e-46 155.9 0.0 1.2e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF5432 PF17497.2 OAJ19200.1 - 0.19 11.8 0.1 0.59 10.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5432) Pribosyltran_N PF13793.6 OAJ19202.1 - 6.7e-44 148.5 0.0 7e-43 145.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAJ19202.1 - 7.3e-35 120.7 2.8 1.8e-31 109.6 0.6 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAJ19202.1 - 2.6e-15 56.3 1.4 5.2e-14 52.1 0.9 2.8 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAJ19202.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 OAJ19202.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase Sterol_MT_C PF08498.10 OAJ19202.1 - 0.16 12.3 1.3 5.6 7.4 0.1 2.5 1 1 1 2 2 2 0 Sterol methyltransferase C-terminal Rft-1 PF04506.13 OAJ19203.1 - 4.9e-109 365.4 0.0 5.6e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Rft protein Git3 PF11710.8 OAJ19204.1 - 1.3e-09 38.2 8.8 3.4e-09 36.8 8.8 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAJ19204.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OAJ19204.1 - 0.00063 19.8 0.5 0.0042 17.1 0.0 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Cwf_Cwc_15 PF04889.12 OAJ19204.1 - 4.4 7.0 5.3 7.9 6.1 0.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MULE PF10551.9 OAJ19205.1 - 9.6e-17 61.2 0.1 3.4e-16 59.5 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ19205.1 - 4.1e-07 29.2 1.1 1.6e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 OAJ19205.1 - 0.0002 21.1 0.1 0.00052 19.8 0.1 1.7 1 0 0 1 1 1 1 Transposase FAR1 PF03101.15 OAJ19205.1 - 0.0013 19.3 0.0 0.0031 18.2 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_Tnp_IS240 PF13610.6 OAJ19205.1 - 0.0048 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 DDE domain rve PF00665.26 OAJ19205.1 - 0.011 15.9 0.2 0.029 14.6 0.2 1.7 1 0 0 1 1 1 0 Integrase core domain DUF5575 PF17738.1 OAJ19205.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Abhydrolase_1 PF00561.20 OAJ19206.1 - 1.8e-36 126.1 0.1 2.3e-18 66.8 0.1 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold COX6A PF02046.15 OAJ19208.1 - 1.2e-31 109.5 0.1 1.4e-31 109.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Xpo1 PF08389.12 OAJ19243.1 - 0.0026 17.8 0.0 0.0058 16.7 0.0 1.5 2 0 0 2 2 2 1 Exportin 1-like protein p450 PF00067.22 OAJ19244.1 - 2.2e-05 23.4 0.0 2.2e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sporozoite_P67 PF05642.11 OAJ19245.1 - 0.24 9.5 21.3 0.28 9.2 21.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen D123 PF07065.14 OAJ19245.1 - 0.92 8.6 13.4 1 8.4 13.4 1.2 1 0 0 1 1 1 0 D123 POX PF07526.11 OAJ19245.1 - 5.8 7.5 9.8 6.8 7.3 9.8 1.2 1 0 0 1 1 1 0 Associated with HOX CobT PF06213.12 OAJ19245.1 - 8.9 5.6 33.6 9.1 5.6 33.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Fasciclin PF02469.22 OAJ19246.1 - 3.4e-11 43.5 0.0 5.1e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain DDE_1 PF03184.19 OAJ19247.1 - 7.3e-22 77.9 0.0 9.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OAJ19247.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease FAD_binding_7 PF03441.14 OAJ19248.1 - 5.4e-48 163.2 0.9 1.2e-45 155.5 0.9 2.3 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ19248.1 - 3e-35 121.6 0.0 5.1e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-H2C2_2 PF13465.6 OAJ19249.1 - 6.1e-11 42.2 9.4 0.00014 22.1 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ19249.1 - 9.9e-11 41.5 9.7 0.0011 19.7 0.0 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ19249.1 - 1.1e-08 35.0 23.1 0.00066 20.0 0.0 4.9 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAJ19249.1 - 0.007 16.3 4.5 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAJ19249.1 - 0.031 14.2 0.9 0.031 14.2 0.9 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIA PF03153.13 OAJ19249.1 - 0.063 13.3 33.7 0.012 15.6 11.2 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IBR PF01485.21 OAJ19249.1 - 0.11 12.8 1.7 0.27 11.5 1.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 OAJ19249.1 - 0.44 10.9 16.1 1 9.8 0.0 5.3 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 OAJ19249.1 - 6.1 6.9 7.6 0.4 10.7 0.2 2.8 3 0 0 3 3 3 0 BED zinc finger TauD PF02668.16 OAJ19250.1 - 6.9e-32 111.3 2.3 6.9e-32 111.3 0.1 2.1 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAJ19250.1 - 4.1e-14 53.0 1.9 4.1e-13 49.8 0.0 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF971) Pex14_N PF04695.13 OAJ19250.1 - 6.4 7.4 18.3 1.8 9.2 3.0 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_cc PF11790.8 OAJ19251.1 - 2.4e-49 168.1 1.7 3e-49 167.8 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VPS28 PF03997.12 OAJ19286.1 - 3.6e-58 196.4 0.0 5.8e-58 195.7 0.0 1.3 1 1 0 1 1 1 1 VPS28 protein PAPS_reduct PF01507.19 OAJ19287.1 - 1.5e-36 126.1 0.0 1.9e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Myb_DNA-bind_3 PF12776.7 OAJ19289.1 - 7.4e-05 23.7 1.7 0.0073 17.3 0.1 2.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Fibrillarin_2 PF10113.9 OAJ19289.1 - 0.093 11.3 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein TFIIA PF03153.13 OAJ19289.1 - 0.28 11.1 32.2 0.19 11.7 20.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MBF1 PF08523.10 OAJ19291.1 - 1.6e-19 70.1 0.8 3.3e-19 69.1 0.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAJ19291.1 - 2.1e-11 43.7 0.3 3.7e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OAJ19291.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OAJ19291.1 - 0.0055 16.7 0.2 0.0086 16.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HpcH_HpaI PF03328.14 OAJ19291.1 - 0.043 13.0 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family SNF5 PF04855.12 OAJ19292.1 - 2e-56 191.5 2.8 1.8e-53 181.8 2.8 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 FbpC_C_terminal PF17845.1 OAJ19292.1 - 0.0067 16.5 0.3 0.016 15.3 0.3 1.5 1 0 0 1 1 1 1 FbpC C-terminal regulatory nucleotide binding domain DUF3432 PF11914.8 OAJ19292.1 - 6.6 7.0 12.4 12 6.2 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Phage_holin_3_6 PF07332.11 OAJ19293.1 - 0.018 15.0 1.9 0.45 10.6 0.1 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MscS_TM PF12794.7 OAJ19293.1 - 0.83 8.4 5.7 12 4.6 3.6 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 NA37 PF04245.13 OAJ19294.1 - 0.035 13.6 1.4 0.053 13.0 1.4 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein X PF00739.19 OAJ19294.1 - 4.5 7.4 5.6 8.4 6.5 5.6 1.5 1 0 0 1 1 1 0 Trans-activation protein X Polysacc_synt_4 PF04669.13 OAJ19295.1 - 2.2e-19 69.7 3.1 9.9e-18 64.4 3.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis NDUF_B12 PF08122.12 OAJ19296.1 - 1.4e-16 60.2 0.2 2.1e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family TPR_2 PF07719.17 OAJ19297.1 - 0.01 15.9 0.1 13 6.2 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19297.1 - 0.073 13.4 4.7 1.3 9.4 1.0 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat AAA_10 PF12846.7 OAJ19297.1 - 0.28 10.1 3.7 0.87 8.4 0.4 2.2 2 0 0 2 2 2 0 AAA-like domain Nbl1_Borealin_N PF10444.9 OAJ19297.1 - 0.53 10.0 3.0 1.7 8.3 0.2 3.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF4439 PF14530.6 OAJ19297.1 - 2.9 8.6 8.2 0.57 10.9 3.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4439) Pkinase PF00069.25 OAJ19298.1 - 2.9e-39 135.0 0.0 7.5e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19298.1 - 1.4e-23 83.5 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ19298.1 - 9.9e-08 31.2 0.0 2.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase ATP-synt_C PF00137.21 OAJ19298.1 - 0.15 12.4 4.7 0.3 11.5 4.7 1.4 1 0 0 1 1 1 0 ATP synthase subunit C RRM_1 PF00076.22 OAJ19299.1 - 5.3e-16 58.2 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ19299.1 - 0.00089 18.8 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ19299.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 OAJ19299.1 - 0.026 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PGI PF00342.19 OAJ19300.1 - 4.5e-225 747.8 0.1 5.2e-225 747.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Inhibitor_Mig-6 PF11555.8 OAJ19300.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 DUF5052 PF16475.5 OAJ19300.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) F1F0-ATPsyn_F PF10791.9 OAJ19301.1 - 8.3e-31 106.3 0.0 1.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Hexapep PF00132.24 OAJ19302.1 - 1.8e-09 36.9 8.7 5e-06 26.0 1.1 4.1 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ19302.1 - 0.0002 21.1 8.6 0.25 11.1 0.0 3.6 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2673 PF10880.8 OAJ19340.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Aminotran_4 PF01063.19 OAJ19343.1 - 2e-26 93.3 0.0 5.7e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV tRNA_U5-meth_tr PF05958.11 OAJ19344.1 - 1.6e-18 66.8 0.0 3.5e-17 62.4 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 OAJ19344.1 - 1.5e-05 24.7 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OAJ19344.1 - 5.3e-05 23.8 0.0 0.00022 21.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ19344.1 - 8.6e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.20 OAJ19344.1 - 0.0002 21.3 1.3 0.00044 20.2 1.3 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_11 PF08241.12 OAJ19344.1 - 0.002 18.7 0.0 0.006 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OAJ19344.1 - 0.0063 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OAJ19344.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain MEF2_binding PF09047.10 OAJ19344.1 - 0.019 14.8 0.1 3.2 7.7 0.0 2.9 2 0 0 2 2 2 0 MEF2 binding PrmA PF06325.13 OAJ19344.1 - 0.028 13.8 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 OAJ19344.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein MSP1a PF11670.8 OAJ19344.1 - 0.48 9.7 6.3 0.96 8.7 6.3 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) SKN1 PF03935.15 OAJ19345.1 - 3.3e-182 606.4 0.5 4.2e-182 606.0 0.5 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 OAJ19345.1 - 0.00032 20.2 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Cwf_Cwc_15 PF04889.12 OAJ19348.1 - 0.24 11.1 1.5 0.33 10.7 1.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CNDH2_M PF16869.5 OAJ19348.1 - 0.66 10.7 9.0 1.4 9.6 9.0 1.5 1 0 0 1 1 1 0 PF16858 Med13_C PF06333.12 OAJ19348.1 - 2.5 7.3 11.2 3.7 6.7 11.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Acyltransferase PF01553.21 OAJ19349.1 - 2.2e-24 85.6 0.0 3.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAJ19349.1 - 7.9e-08 32.3 0.3 2.9e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Actin PF00022.19 OAJ19386.1 - 3.4e-19 68.7 0.0 2.1e-10 39.8 0.0 3.3 3 1 0 3 3 3 3 Actin Actin_micro PF17003.5 OAJ19386.1 - 5.5e-11 42.3 0.0 9.4e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family SAC3_GANP PF03399.16 OAJ19387.1 - 7e-25 88.0 5.2 7.2e-23 81.4 5.2 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAJ19387.1 - 0.001 19.0 0.2 0.0029 17.6 0.2 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GST_C_6 PF17171.4 OAJ19389.1 - 0.0019 18.0 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain p47_phox_C PF08944.11 OAJ19389.1 - 0.49 9.8 7.7 0.19 11.1 1.0 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain DUF3188 PF11384.8 OAJ19390.1 - 0.0087 15.7 1.4 0.018 14.7 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) PspB PF06667.12 OAJ19390.1 - 0.075 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B Neur_chan_memb PF02932.16 OAJ19390.1 - 0.099 12.7 6.0 0.3 11.1 6.0 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4381 PF14316.6 OAJ19390.1 - 0.24 11.6 1.5 0.3 11.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) RCR PF12273.8 OAJ19390.1 - 3.6 8.3 11.8 1.4 9.6 2.4 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red YEATS PF03366.16 OAJ19391.1 - 1.8e-38 130.4 0.0 2.9e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 YEATS family DUF2570 PF10828.8 OAJ19391.1 - 1.5 8.6 4.1 1.3 8.9 2.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Kinesin PF00225.23 OAJ19392.1 - 3.8e-93 312.1 0.3 3.5e-92 308.9 0.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ19392.1 - 2.4e-49 167.1 0.0 5.1e-49 166.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Macoilin PF09726.9 OAJ19392.1 - 3.4e-05 22.6 10.8 3.4e-05 22.6 10.8 1.4 2 0 0 2 2 2 1 Macoilin family CENP-K PF11802.8 OAJ19392.1 - 0.025 14.2 13.4 0.05 13.2 13.4 1.5 1 0 0 1 1 1 0 Centromere-associated protein K Surfac_D-trimer PF09006.11 OAJ19392.1 - 0.036 14.0 4.0 0.063 13.2 2.6 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation AAA_13 PF13166.6 OAJ19392.1 - 2.7 6.5 15.4 5.2 5.6 15.4 1.4 1 0 0 1 1 1 0 AAA domain BAG PF02179.16 OAJ19393.1 - 4.5e-14 52.6 0.0 1.3e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OAJ19393.1 - 9.6e-09 34.9 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TarH PF02203.15 OAJ19393.1 - 0.0065 16.4 6.0 0.011 15.7 6.0 1.3 1 0 0 1 1 1 1 Tar ligand binding domain homologue Ubiquitin_2 PF14560.6 OAJ19393.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Thioredoxin_8 PF13905.6 OAJ19394.1 - 7.2e-10 39.1 0.0 2.4e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OAJ19394.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ19394.1 - 0.0064 16.4 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family DUF3439 PF11921.8 OAJ19394.1 - 0.33 10.9 10.0 0.63 10.0 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Anoctamin PF04547.12 OAJ19395.1 - 2.5e-97 326.6 0.2 3.1e-97 326.3 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel LapA_dom PF06305.11 OAJ19395.1 - 2.4 8.0 6.2 0.69 9.8 1.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain GATase_2 PF00310.21 OAJ19397.1 - 6.4e-179 595.1 0.0 8.6e-179 594.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAJ19397.1 - 2.6e-156 520.4 0.1 7.4e-156 518.9 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAJ19397.1 - 3.6e-111 371.1 0.0 9.6e-111 369.7 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAJ19397.1 - 3.5e-87 290.9 2.6 6.2e-87 290.1 2.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAJ19397.1 - 2.1e-28 99.4 0.1 1.9e-27 96.3 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAJ19397.1 - 1.4e-21 76.3 0.1 3.9e-21 74.9 0.0 1.8 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OAJ19397.1 - 4.4e-09 36.4 0.0 1.5e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAJ19397.1 - 1.9e-07 30.7 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAJ19397.1 - 3.9e-07 30.5 3.2 0.00014 22.3 0.3 3.9 3 1 1 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ19397.1 - 1.8e-05 24.3 0.3 1.8e-05 24.3 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ19397.1 - 5.1e-05 22.7 0.2 0.041 13.1 0.0 3.9 3 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ19397.1 - 9e-05 22.2 1.4 0.0011 18.6 0.5 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ19397.1 - 9.8e-05 21.2 0.2 9.8e-05 21.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ19397.1 - 0.00018 20.9 0.1 0.5 9.6 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAJ19397.1 - 0.00039 19.8 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAJ19397.1 - 0.00053 19.2 3.0 0.00063 18.9 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 OAJ19397.1 - 0.00093 18.5 0.1 0.00093 18.5 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAJ19397.1 - 0.0025 16.9 0.1 0.67 8.9 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein FMN_dh PF01070.18 OAJ19397.1 - 0.0054 15.8 3.4 0.021 13.9 1.8 2.6 3 0 0 3 3 3 1 FMN-dependent dehydrogenase GIDA PF01134.22 OAJ19397.1 - 0.0097 15.0 0.6 0.061 12.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 OAJ19397.1 - 0.0099 15.2 0.1 0.049 13.0 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAJ19397.1 - 0.013 15.9 0.9 1.1 9.7 0.1 3.1 2 0 0 2 2 2 0 Putative NAD(P)-binding GATase_6 PF13522.6 OAJ19397.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_Gly3P_dh_N PF01210.23 OAJ19397.1 - 0.096 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.24 OAJ19397.1 - 0.17 11.7 2.2 38 4.0 0.1 3.3 1 1 2 3 3 3 0 DJ-1/PfpI family AdoHcyase_NAD PF00670.21 OAJ19397.1 - 0.3 11.1 3.9 15 5.6 0.0 3.5 4 0 0 4 4 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rossmann-like PF10727.9 OAJ19397.1 - 0.4 10.5 1.7 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain MFS_1 PF07690.16 OAJ19431.1 - 1.2e-37 129.7 39.8 1.4e-31 109.7 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2484 PF10658.9 OAJ19431.1 - 0.009 16.3 4.0 0.009 16.3 4.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2484) DUF4023 PF13215.6 OAJ19431.1 - 0.32 11.0 0.5 3 7.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DUF3693 PF12472.8 OAJ19431.1 - 0.35 10.6 1.9 11 5.8 0.1 3.2 3 0 0 3 3 3 0 Phage related protein RabGAP-TBC PF00566.18 OAJ19432.1 - 2.9e-22 79.4 3.1 5.4e-18 65.4 0.8 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain UCH PF00443.29 OAJ19434.1 - 6e-30 104.6 0.0 1.6e-29 103.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ19434.1 - 3.2e-11 43.4 0.0 5.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OAJ19434.1 - 0.0034 17.0 0.2 0.016 14.9 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 OAJ19435.1 - 5e-48 161.0 9.0 2.3e-16 59.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein K_channel_TID PF07941.11 OAJ19435.1 - 0.075 13.5 0.3 0.075 13.5 0.3 2.4 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain SNF2_N PF00176.23 OAJ19436.1 - 1.6e-57 194.8 0.1 2.5e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ19436.1 - 6e-12 45.9 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XPG_I PF00867.18 OAJ19436.1 - 3.5e-06 27.3 0.0 1.3e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 XPG I-region zf-RING_5 PF14634.6 OAJ19436.1 - 3.6e-05 23.6 0.6 8.1e-05 22.5 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ19436.1 - 0.0017 18.3 0.2 0.0039 17.2 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ19436.1 - 0.0021 17.9 0.7 0.0021 17.9 0.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ19436.1 - 0.0034 17.2 1.9 0.0034 17.2 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) XPG_N PF00752.17 OAJ19436.1 - 0.0062 17.0 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain zf-C3HC4_3 PF13920.6 OAJ19436.1 - 0.0076 16.1 3.0 0.016 15.1 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ19436.1 - 0.0099 15.7 0.9 0.023 14.6 0.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAJ19436.1 - 0.016 15.6 1.0 0.039 14.3 1.0 1.6 1 0 0 1 1 1 0 Ring finger domain DUF5643 PF18705.1 OAJ19436.1 - 0.09 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5643) zf-C3HC4_4 PF15227.6 OAJ19436.1 - 0.097 12.9 1.6 0.34 11.1 1.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING 5_3_exonuc PF01367.20 OAJ19436.1 - 0.11 13.1 0.0 0.45 11.1 0.0 2.0 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold ResIII PF04851.15 OAJ19436.1 - 0.35 10.8 4.5 1.1 9.2 0.1 3.1 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit IF-2B PF01008.17 OAJ19437.1 - 1.7e-34 119.3 0.3 6.4e-31 107.6 0.0 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family Nop14 PF04147.12 OAJ19437.1 - 0.031 12.5 10.2 0.053 11.7 10.2 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAJ19437.1 - 0.81 8.1 12.0 1.5 7.3 12.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 OAJ19437.1 - 6.8 5.9 14.9 11 5.3 14.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1244 PF06844.11 OAJ19438.1 - 0.04 14.1 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf_CCCH_4 PF18345.1 OAJ19439.1 - 0.00011 22.1 5.2 0.00019 21.4 5.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ19439.1 - 0.0019 17.9 2.9 0.0033 17.2 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAJ19439.1 - 0.015 15.2 2.0 0.028 14.4 2.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MutS_V PF00488.21 OAJ19440.1 - 9.5e-60 201.8 0.1 2.5e-58 197.2 0.1 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ19440.1 - 2e-35 122.8 0.9 3.9e-35 121.8 0.9 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ19440.1 - 4.2e-24 85.0 0.0 1.4e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAJ19440.1 - 7.8e-10 39.2 0.0 1.8e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAJ19440.1 - 9.9e-09 35.4 0.0 2.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV COesterase PF00135.28 OAJ19475.1 - 8.6e-87 292.1 0.0 1e-86 291.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ19475.1 - 0.00039 20.3 0.1 0.00078 19.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ19475.1 - 0.01 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family ANTH PF07651.16 OAJ19476.1 - 5.4e-48 163.4 0.0 7.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAJ19476.1 - 3.9e-05 23.7 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ENTH domain F-box-like PF12937.7 OAJ19477.1 - 0.06 13.3 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like Phyto_Pns9_10 PF05878.11 OAJ19477.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 HSBP1 PF06825.12 OAJ19478.1 - 1.1e-14 54.0 0.4 1.4e-14 53.6 0.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Vps16_C PF04840.12 OAJ19479.1 - 1.4e-07 30.9 0.3 0.0042 16.2 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region K_channel_TID PF07941.11 OAJ19479.1 - 0.00075 19.9 11.7 0.00075 19.9 11.7 2.3 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.32 OAJ19480.1 - 9.9e-09 35.7 0.8 0.0037 18.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.33 OAJ19480.1 - 4.1e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain HAD_2 PF13419.6 OAJ19480.1 - 3.9e-05 23.8 0.1 7.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase F-box-like PF12937.7 OAJ19480.1 - 0.00017 21.4 0.1 0.00042 20.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF2608 PF11019.8 OAJ19480.1 - 0.00083 18.9 0.0 0.0058 16.2 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2608) Hydrolase PF00702.26 OAJ19480.1 - 0.0015 18.9 0.0 0.033 14.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nup160 PF11715.8 OAJ19480.1 - 0.028 13.1 0.4 0.082 11.5 0.0 1.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Mg_trans_NIPA PF05653.14 OAJ19481.1 - 4.2e-92 308.4 26.9 5.7e-92 308.0 26.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAJ19481.1 - 0.00016 21.9 10.2 0.00016 21.9 10.2 3.6 2 2 1 3 3 3 1 EamA-like transporter family PP2C PF00481.21 OAJ19482.1 - 6.8e-48 163.5 0.1 1.3e-47 162.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAJ19482.1 - 2.8e-39 132.7 53.3 1.1e-08 34.7 3.0 9.6 4 2 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OAJ19482.1 - 1.3e-33 114.4 65.5 9.1e-06 25.9 0.4 12.2 4 2 11 17 17 17 15 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OAJ19482.1 - 1.1e-24 87.0 0.0 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 OAJ19482.1 - 0.0003 20.9 34.0 4.4 8.2 0.0 13.1 11 3 0 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.6 OAJ19482.1 - 0.032 13.7 17.8 0.022 14.3 1.5 4.2 2 1 3 5 5 5 0 Leucine-rich repeat Pkinase PF00069.25 OAJ19483.1 - 9.6e-51 172.7 0.0 9.6e-51 172.7 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19483.1 - 1.2e-19 70.6 0.0 1.2e-19 70.6 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OAJ19483.1 - 0.0038 17.2 0.1 0.0038 17.2 0.1 3.8 3 1 0 4 4 4 1 Phosphotransferase enzyme family STE2 PF02116.15 OAJ19484.1 - 0.00025 20.4 3.2 0.00045 19.6 3.2 1.3 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR ABC_tran PF00005.27 OAJ19517.1 - 1e-28 100.6 0.0 2.3e-28 99.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 OAJ19517.1 - 1.6e-12 47.7 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAJ19517.1 - 1.2e-06 28.1 0.0 4.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ19517.1 - 0.0032 17.9 0.2 0.017 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAJ19517.1 - 0.01 15.6 0.3 0.028 14.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 OAJ19517.1 - 0.013 15.7 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 OAJ19517.1 - 0.022 14.0 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 OAJ19517.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OAJ19517.1 - 0.034 13.9 0.0 0.31 10.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 OAJ19517.1 - 0.056 13.7 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OAJ19517.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABA_GPCR PF12430.8 OAJ19518.1 - 3.6e-35 121.3 6.3 9.2e-35 120.0 6.3 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAJ19518.1 - 5.2e-14 52.1 0.9 1.2e-13 51.0 0.9 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal LcrR PF09621.10 OAJ19518.1 - 0.031 13.7 0.1 0.077 12.4 0.1 1.7 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) SBDS PF01172.18 OAJ19519.1 - 9.6e-13 48.0 0.6 7.3e-12 45.2 0.6 1.9 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF2439 PF10382.9 OAJ19519.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2439) Ribosomal_L13 PF00572.18 OAJ19519.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L13 PI3_PI4_kinase PF00454.27 OAJ19520.1 - 3e-36 125.5 0.0 5.9e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase K_oxygenase PF13434.6 OAJ19521.1 - 1.6e-89 300.4 0.0 2.6e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ19521.1 - 1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ19521.1 - 0.00055 19.3 0.0 0.0076 15.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ19521.1 - 0.013 16.1 0.0 0.074 13.6 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 OAJ19522.1 - 0.00036 21.2 0.0 0.0012 19.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ19522.1 - 0.001 18.9 0.2 0.002 17.9 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ19522.1 - 0.004 16.9 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAJ19522.1 - 0.0057 16.5 0.0 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ19522.1 - 0.17 12.6 0.0 0.48 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAJ19522.1 - 0.22 10.4 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MRP-L20 PF12824.7 OAJ19523.1 - 1.9e-18 67.2 0.1 3.1e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 GntR PF00392.21 OAJ19523.1 - 0.15 11.8 0.1 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family PEPCK_ATP PF01293.20 OAJ19524.1 - 1.4e-214 713.0 0.0 1.7e-214 712.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 OAJ19524.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 OAJ19526.1 - 4.3e-92 308.7 20.0 1.5e-50 172.4 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ19526.1 - 1.3e-31 109.9 0.0 2.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAJ19526.1 - 2.6e-06 27.0 0.5 4.3e-05 23.1 0.3 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ19526.1 - 0.0028 18.0 0.3 0.27 11.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ19526.1 - 0.0042 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.17 OAJ19526.1 - 0.0059 16.7 0.1 0.012 15.8 0.1 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 OAJ19526.1 - 0.0094 16.4 1.4 0.82 10.0 2.4 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OAJ19526.1 - 0.034 13.9 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAJ19526.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF349 PF03993.12 OAJ19527.1 - 3.8 7.9 10.2 0.13 12.6 1.8 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Cnd3 PF12719.7 OAJ19563.1 - 3.5e-77 259.5 0.0 3.6e-75 252.9 0.0 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 OAJ19563.1 - 0.00012 22.1 3.0 5 7.2 0.0 4.6 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ19563.1 - 0.00016 22.0 12.3 0.0015 18.8 0.8 5.4 5 1 1 6 6 6 2 HEAT repeats CLASP_N PF12348.8 OAJ19563.1 - 0.0025 17.4 0.5 5.6 6.4 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 OAJ19563.1 - 0.0067 16.6 10.5 19 5.9 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 OAJ19563.1 - 0.056 14.0 5.8 46 4.7 0.0 6.0 6 1 0 6 6 6 0 HEAT-like repeat FANCI_S2 PF14676.6 OAJ19563.1 - 0.24 11.7 1.3 6.1 7.1 0.0 2.8 2 1 0 2 2 2 0 FANCI solenoid 2 RTP1_C1 PF10363.9 OAJ19563.1 - 0.38 11.0 2.6 2 8.6 0.0 3.3 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Homeodomain PF00046.29 OAJ19564.1 - 1.1e-18 66.8 4.9 2e-18 66.0 4.9 1.5 1 0 0 1 1 1 1 Homeodomain Rad4 PF03835.15 OAJ19565.1 - 1.7e-26 92.7 0.0 1.7e-26 92.7 0.0 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAJ19565.1 - 2.5e-24 85.5 0.0 4.5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAJ19565.1 - 8.9e-18 63.9 0.0 1.6e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 OAJ19565.1 - 1.5e-07 31.8 1.1 1.4e-06 28.7 0.0 3.1 3 0 0 3 3 3 1 Transglutaminase-like superfamily BHD_2 PF10404.9 OAJ19565.1 - 1e-05 26.3 0.3 1e-05 26.3 0.3 4.0 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 EBP PF05241.12 OAJ19566.1 - 4.2e-61 205.5 8.8 5e-61 205.3 8.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_binding_8 PF13450.6 OAJ19566.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF996 PF06195.13 OAJ19566.1 - 0.05 13.9 0.8 0.078 13.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF996) HR_lesion PF05514.11 OAJ19566.1 - 0.27 11.4 6.1 1.3 9.2 0.1 2.5 3 0 0 3 3 3 0 HR-like lesion-inducing Nas2_N PF18265.1 OAJ19567.1 - 9.8e-26 89.5 0.8 1.5e-25 88.9 0.8 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OAJ19567.1 - 4.8e-09 35.9 0.1 9.6e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OAJ19567.1 - 1.2e-05 25.5 0.0 2.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAJ19567.1 - 0.00087 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OAJ19567.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.6 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain dCMP_cyt_deam_1 PF00383.23 OAJ19569.1 - 1.1e-25 89.4 0.7 1.9e-25 88.7 0.7 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ19569.1 - 1.5e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 OAJ19569.1 - 0.0002 21.9 0.0 0.00057 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ19569.1 - 0.017 15.2 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SNAD4 PF18750.1 OAJ19569.1 - 0.045 13.9 0.7 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 OAJ19569.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase TRAM_LAG1_CLN8 PF03798.16 OAJ19570.1 - 3e-34 118.5 24.5 3e-34 118.5 24.5 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAJ19570.1 - 2.3e-19 68.8 0.1 7.4e-19 67.2 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein E1_dh PF00676.20 OAJ19573.1 - 7.3e-62 209.0 0.0 1.3e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 OAJ19573.1 - 5.4e-61 205.4 0.0 7.9e-61 204.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OAJ19573.1 - 2.1e-50 170.4 0.0 4.1e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OAJ19573.1 - 5.9e-15 54.6 0.2 1.3e-14 53.4 0.2 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus HGTP_anticodon PF03129.20 OAJ19574.1 - 1.2e-20 73.5 0.5 3.8e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAJ19574.1 - 5.3e-09 36.3 0.0 1.2e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) InPase PF18823.1 OAJ19574.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase Mito_carr PF00153.27 OAJ19575.1 - 3.2e-41 139.1 9.0 8.5e-16 57.7 0.6 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1691 PF07950.11 OAJ19614.1 - 1.9e-05 25.3 7.1 3.6e-05 24.4 0.5 3.4 3 2 0 3 3 3 1 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 OAJ19614.1 - 0.00018 21.6 1.1 0.0019 18.2 0.1 2.6 2 1 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4405 PF14358.6 OAJ19614.1 - 0.011 16.3 0.5 0.46 11.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Yip1 PF04893.17 OAJ19615.1 - 5.5e-09 36.0 11.5 5.5e-09 36.0 11.5 1.5 2 0 0 2 2 2 1 Yip1 domain DUF2070 PF09843.9 OAJ19615.1 - 2.5 6.3 8.2 3.3 5.9 8.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HOIP-UBA PF16678.5 OAJ19616.1 - 0.0022 18.0 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 HOIP UBA domain pair UBA PF00627.31 OAJ19616.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain SAICAR_synt PF01259.18 OAJ19617.1 - 2.8e-91 305.6 0.0 5.3e-91 304.7 0.0 1.4 1 1 0 1 1 1 1 SAICAR synthetase Pro-kuma_activ PF09286.11 OAJ19617.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain SCA7 PF08313.12 OAJ19618.1 - 2.5e-25 88.2 0.2 5.3e-25 87.1 0.2 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain MAS20 PF02064.15 OAJ19618.1 - 0.016 15.3 4.6 0.016 15.3 4.6 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor TAF4 PF05236.14 OAJ19618.1 - 0.26 11.0 13.4 0.021 14.6 6.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Rrn6 PF10214.9 OAJ19618.1 - 0.82 8.1 2.3 0.93 7.9 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pro-kuma_activ PF09286.11 OAJ19619.1 - 4.8e-17 62.6 0.0 1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAJ19619.1 - 2.9e-10 39.9 2.6 2.9e-10 39.9 2.6 1.7 2 0 0 2 2 2 1 Subtilase family Jiraiya PF15038.6 OAJ19620.1 - 0.11 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Jiraiya zf-C3Hc3H PF13891.6 OAJ19620.1 - 0.79 10.1 6.6 0.21 12.0 2.4 2.0 1 1 1 2 2 2 0 Potential DNA-binding domain NTP_transf_9 PF04248.12 OAJ19621.1 - 5.9e-31 106.2 1.0 6.2e-30 102.9 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF427) Peptidase_M43 PF05572.13 OAJ19622.1 - 9.1e-08 32.2 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Exonuc_VII_L PF02601.15 OAJ19624.1 - 0.33 10.5 4.9 0.69 9.4 4.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit LCM PF04072.14 OAJ19625.1 - 4.2e-14 52.9 0.0 5.5e-08 33.0 0.0 2.6 3 0 0 3 3 3 2 Leucine carboxyl methyltransferase PC_rep PF01851.22 OAJ19626.1 - 2e-42 141.5 22.4 1.2e-09 38.1 0.0 8.9 8 0 0 8 8 8 8 Proteasome/cyclosome repeat RPN2_C PF18004.1 OAJ19626.1 - 1.5e-40 138.7 0.2 1.5e-40 138.7 0.2 2.3 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 OAJ19626.1 - 1.3e-22 79.9 5.9 2.8e-14 53.3 0.0 4.9 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 OAJ19626.1 - 2.7e-05 24.0 2.7 1 9.8 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 OAJ19626.1 - 4.8e-05 23.8 5.5 2.8 8.5 0.1 5.8 5 1 1 6 6 6 3 HEAT-like repeat HEAT_PBS PF03130.16 OAJ19626.1 - 0.0042 17.6 2.1 71 4.5 0.0 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OAJ19626.1 - 0.1 12.6 0.0 5.8 6.9 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 OAJ19626.1 - 0.14 12.7 6.9 3.7 8.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ19626.1 - 1.8 8.9 4.5 5.6 7.3 0.2 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3439 PF11921.8 OAJ19626.1 - 1.9 8.5 4.0 4.2 7.4 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S15 PF02129.18 OAJ19627.1 - 5.5e-08 32.7 0.1 1.3e-05 24.9 0.0 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAJ19627.1 - 6.8e-08 32.5 0.1 0.00023 20.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ19627.1 - 3.3e-07 29.8 0.1 0.00077 18.8 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAJ19627.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 OAJ19627.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ku PF02735.16 OAJ19665.1 - 3.5e-24 85.6 0.1 5.9e-23 81.6 0.0 2.9 3 1 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 OAJ19665.1 - 5.6e-19 68.4 0.0 5.2e-18 65.3 0.0 2.6 3 0 0 3 3 3 1 Ku C terminal domain like Pyridoxal_deC PF00282.19 OAJ19666.1 - 1.1e-65 221.8 0.0 1.6e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAJ19666.1 - 0.0082 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GMP_synt_C PF00958.22 OAJ19667.1 - 1.1e-43 147.2 0.0 2e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OAJ19667.1 - 2.1e-36 125.5 0.0 3.4e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 OAJ19667.1 - 7.6e-11 41.6 0.1 1.4e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAJ19667.1 - 1.4e-08 34.8 0.0 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 OAJ19667.1 - 0.00057 18.8 0.2 0.001 17.9 0.2 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 OAJ19667.1 - 0.0038 16.8 0.0 0.0076 15.9 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 OAJ19667.1 - 0.017 14.7 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 OAJ19667.1 - 0.073 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 OAJ19667.1 - 0.097 12.4 0.2 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Pil1 PF13805.6 OAJ19668.1 - 1e-33 117.0 0.2 1e-33 117.0 0.2 1.7 2 0 0 2 2 2 1 Eisosome component PIL1 FUSC PF04632.12 OAJ19668.1 - 0.0038 15.8 0.9 0.0057 15.3 0.9 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family SUIM_assoc PF16619.5 OAJ19668.1 - 0.013 15.6 12.2 0.17 12.0 4.5 3.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GrpE PF01025.19 OAJ19668.1 - 0.062 13.0 0.3 0.16 11.6 0.3 1.7 1 1 0 1 1 1 0 GrpE DUF1664 PF07889.12 OAJ19668.1 - 0.098 12.7 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OAJ19668.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.5 3 0 0 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 OAJ19668.1 - 0.11 12.6 0.2 0.11 12.6 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAJ19668.1 - 0.12 11.3 0.7 0.21 10.5 0.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 OAJ19668.1 - 0.16 12.1 1.3 0.31 11.1 1.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor TBCC_N PF16752.5 OAJ19668.1 - 1.2 9.7 5.4 0.28 11.6 0.3 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain MGC-24 PF05283.11 OAJ19670.1 - 3.3 8.2 16.6 6.6 7.2 16.6 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RA PF00788.23 OAJ19671.1 - 5.1e-11 43.1 4.5 1.5e-09 38.3 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 OAJ19671.1 - 4.7e-07 29.3 0.0 9.9e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Med15 PF09606.10 OAJ19671.1 - 0.0015 17.3 30.3 0.0015 17.3 30.3 3.5 3 1 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal SH3_9 PF14604.6 OAJ19671.1 - 0.0083 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain MRI PF15325.6 OAJ19672.1 - 0.43 11.7 5.5 0.55 11.3 5.5 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection CCDC106 PF15794.5 OAJ19672.1 - 0.66 9.6 4.7 0.7 9.6 4.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Hexapep PF00132.24 OAJ19673.1 - 3.3e-07 29.8 14.0 0.066 13.0 1.2 4.0 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ19673.1 - 0.00093 18.9 12.3 0.031 14.0 3.8 3.4 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MIF4G PF02854.19 OAJ19674.1 - 3.4e-13 49.7 0.0 1.7e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OAJ19674.1 - 6.3e-11 42.3 0.0 1.6e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 MA3 domain Nop14 PF04147.12 OAJ19674.1 - 0.017 13.4 23.4 0.024 12.9 23.4 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 OAJ19674.1 - 0.11 12.6 33.5 0.11 12.5 14.8 2.4 2 0 0 2 2 2 0 YL1 nuclear protein DUF5558 PF17713.1 OAJ19674.1 - 0.19 12.1 5.9 0.48 10.8 4.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5558) COX5B PF01215.19 OAJ19675.1 - 1e-46 157.8 0.0 1.3e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 OAJ19675.1 - 0.00021 21.3 0.4 0.00031 20.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain Mito_carr PF00153.27 OAJ19676.1 - 1.4e-62 207.6 2.4 1.8e-23 82.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vta1 PF04652.16 OAJ19710.1 - 2.5e-50 170.2 0.9 3.6e-50 169.7 0.3 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OAJ19710.1 - 9e-12 44.5 2.2 9e-12 44.5 2.2 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Frag1 PF10277.9 OAJ19711.1 - 0.73 9.3 6.0 24 4.4 6.3 2.1 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family GDA1_CD39 PF01150.17 OAJ19712.1 - 2.6e-75 253.7 0.0 1.6e-58 198.4 0.0 3.0 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OAJ19712.1 - 0.053 13.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Translin PF01997.16 OAJ19713.1 - 7.8e-45 153.4 0.1 2e-33 116.1 0.0 2.2 1 1 1 2 2 2 2 Translin family Sterile PF03015.19 OAJ19713.1 - 0.11 12.7 0.1 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein DAO PF01266.24 OAJ19715.1 - 1.1e-42 146.9 1.5 8e-42 144.1 1.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ19715.1 - 6.8e-05 23.0 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ19715.1 - 0.024 13.9 0.1 0.075 12.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAJ19715.1 - 0.046 14.3 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ19715.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAJ19715.1 - 0.068 11.7 0.1 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) SnoaL_2 PF12680.7 OAJ19715.1 - 0.091 13.4 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain TrkA_N PF02254.18 OAJ19715.1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain TPR_12 PF13424.6 OAJ19717.1 - 0.0051 17.1 13.5 3.1 8.1 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19717.1 - 0.04 14.7 11.3 77 4.5 0.1 7.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19717.1 - 0.085 13.0 8.7 2.2 8.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 OAJ19718.1 - 2.6e-52 177.7 3.9 4.2e-42 144.3 2.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ19718.1 - 5.8e-47 159.7 1.5 7.4e-47 159.3 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ19718.1 - 4.7e-15 56.0 1.8 1.4e-14 54.4 1.8 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAJ19718.1 - 0.00032 20.6 0.6 0.00055 19.9 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ19718.1 - 0.015 16.0 0.2 0.031 15.0 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.20 OAJ19718.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ19718.1 - 0.05 12.9 0.2 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAJ19718.1 - 0.051 13.5 0.5 0.14 12.1 0.5 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF2007 PF09413.10 OAJ19718.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein E1-E2_ATPase PF00122.20 OAJ19719.1 - 5.2e-48 162.9 1.2 5.2e-48 162.9 1.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ19719.1 - 6.7e-46 156.3 4.7 3.3e-45 154.0 2.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ19719.1 - 4.9e-20 72.7 0.0 2.2e-06 28.1 0.2 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ19719.1 - 2.2e-17 62.5 0.0 4.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ19719.1 - 1e-15 57.6 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ19719.1 - 0.00024 20.9 1.7 0.0071 16.1 2.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ19719.1 - 0.078 13.4 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TMEM151 PF14857.6 OAJ19749.1 - 0.0056 15.7 0.3 0.7 8.8 0.0 2.7 2 0 0 2 2 2 2 TMEM151 family TPR_10 PF13374.6 OAJ19750.1 - 0.005 16.7 0.2 4.5 7.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19751.1 - 3.5e-11 43.2 12.6 0.0019 18.4 1.6 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19751.1 - 3.5e-11 42.3 4.1 0.19 11.9 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ19751.1 - 1.2e-10 40.9 3.6 0.28 11.1 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19751.1 - 4.9e-10 38.8 0.6 0.29 11.4 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19751.1 - 3.5e-08 32.9 2.1 1.5 8.7 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19751.1 - 2.6e-05 24.6 6.3 0.021 15.6 2.3 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19751.1 - 3.1e-05 23.7 4.0 5.7 7.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19751.1 - 0.0017 18.8 2.9 0.1 13.1 0.1 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ19751.1 - 0.0062 16.6 0.5 4.4 7.4 0.0 4.1 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 OAJ19751.1 - 0.013 16.1 2.8 41 5.1 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19751.1 - 0.015 15.9 3.6 0.015 15.9 3.6 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ19751.1 - 0.039 14.2 0.4 20 5.5 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAJ19751.1 - 0.42 11.4 0.2 0.42 11.4 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ19751.1 - 1.9 8.2 8.0 3.7 7.3 0.9 4.2 5 0 0 5 5 5 0 TPR repeat DUF4543 PF15076.6 OAJ19752.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Glyco_transf_54 PF04666.13 OAJ19754.1 - 1.3e-05 24.2 0.0 0.023 13.6 0.0 3.0 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MFS_1 PF07690.16 OAJ19755.1 - 7e-39 133.7 40.8 7e-39 133.7 40.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ19755.1 - 9.3e-13 47.4 16.3 1.2e-12 47.1 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PH_9 PF15410.6 OAJ19756.1 - 3.9e-05 24.0 0.5 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 OAJ19756.1 - 0.00019 21.9 0.1 0.0023 18.4 0.1 2.2 2 0 0 2 2 2 1 PH domain NOA36 PF06524.12 OAJ19756.1 - 9.8 5.4 6.5 17 4.6 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein FA_desaturase PF00487.24 OAJ19759.1 - 3.6e-13 50.0 2.8 4.9e-13 49.5 2.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PHBC_N PF12551.8 OAJ19759.1 - 0.19 11.5 2.6 0.2 11.5 0.5 2.3 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal Tfb2 PF03849.14 OAJ19790.1 - 1.8e-16 60.1 0.0 2.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Pkinase PF00069.25 OAJ19791.1 - 0.0012 18.3 0.0 0.0014 18.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Aldedh PF00171.22 OAJ19792.1 - 5.7e-22 77.9 0.0 6.6e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rrn6 PF10214.9 OAJ19793.1 - 0.0035 15.9 16.1 0.0043 15.6 16.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor AF-4 PF05110.13 OAJ19793.1 - 0.0092 14.1 20.8 0.011 13.8 20.8 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Macoilin PF09726.9 OAJ19793.1 - 0.41 9.1 13.0 0.52 8.8 13.0 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 OAJ19793.1 - 0.95 8.2 6.9 1.1 8.0 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 OAJ19793.1 - 3.8 6.3 16.3 4.9 5.9 16.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DTHCT PF08070.11 OAJ19793.1 - 9.9 7.0 36.1 21 5.9 35.8 1.8 1 1 0 1 1 1 0 DTHCT (NUC029) region PI3K_1B_p101 PF10486.9 OAJ19794.1 - 0.0079 14.0 0.6 0.012 13.5 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Roughex PF06020.11 OAJ19794.1 - 0.021 14.0 1.0 0.033 13.3 1.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 OAJ19794.1 - 0.41 9.9 3.1 0.69 9.2 3.1 1.4 1 0 0 1 1 1 0 NOA36 protein Tub_N PF16322.5 OAJ19794.1 - 0.52 10.7 5.2 0.14 12.6 1.3 2.0 2 0 0 2 2 2 0 Tubby N-terminal CENP-B_dimeris PF09026.10 OAJ19794.1 - 1.9 9.0 10.5 5.4 7.5 10.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4813 PF16072.5 OAJ19794.1 - 3.9 7.1 31.3 7.4 6.2 31.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) GREB1 PF15782.5 OAJ19794.1 - 8.8 3.3 6.1 12 2.8 6.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Histone PF00125.24 OAJ19795.1 - 2.7e-46 157.2 1.9 3.1e-46 157.0 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ19795.1 - 7e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ19795.1 - 3.8e-05 23.8 0.7 5.2e-05 23.3 0.2 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ19795.1 - 0.041 14.2 1.5 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OAJ19795.1 - 0.056 14.0 0.8 0.069 13.7 0.8 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain DUF4840 PF16128.5 OAJ19795.1 - 0.18 11.9 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) Ion_trans PF00520.31 OAJ19796.1 - 0.1 11.8 0.2 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 Ion transport protein DUF3541 PF12060.8 OAJ19796.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) tRNA-synt_2b PF00587.25 OAJ19797.1 - 5.7e-32 111.1 0.0 4.3e-29 101.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ19797.1 - 1.1e-16 60.7 0.2 2.5e-16 59.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 OAJ19797.1 - 2.4e-13 49.9 0.0 5.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 OAJ19797.1 - 8.1e-11 41.8 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.13 OAJ19797.1 - 0.041 13.8 0.0 0.5 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF502) SICA_alpha PF12887.7 OAJ19797.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 SICA extracellular alpha domain Peptidase_S8 PF00082.22 OAJ19798.1 - 3.5e-32 111.8 0.8 5.1e-32 111.3 0.8 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ19798.1 - 1.4e-09 38.7 0.0 2.8e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain zf-LYAR PF08790.11 OAJ19799.1 - 1.2e-11 44.3 1.1 1.2e-11 44.3 1.1 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 OAJ19799.1 - 0.18 11.5 1.7 0.63 9.7 1.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain eIF3_subunit PF08597.10 OAJ19800.1 - 9.2e-46 156.7 25.0 1e-45 156.5 25.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 OAJ19800.1 - 0.02 15.2 11.0 0.02 15.2 11.0 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OAJ19800.1 - 0.38 9.0 11.3 0.44 8.8 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ19800.1 - 2.5 6.1 19.0 4 5.4 19.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 OAJ19800.1 - 7.5 6.3 24.8 1.7 8.4 8.9 2.9 2 1 1 3 3 3 0 Pox virus Ag35 surface protein Aldedh PF00171.22 OAJ19801.1 - 1.2e-14 53.7 0.1 1.4e-14 53.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family KDZ PF18758.1 OAJ19802.1 - 4.7e-54 183.3 0.0 8.1e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ19802.1 - 1.1e-06 28.8 0.0 3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ19802.1 - 1.1e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases FA PF08736.11 OAJ19802.1 - 0.031 14.4 1.1 0.14 12.3 1.1 2.2 1 0 0 1 1 1 0 FERM adjacent (FA) CxC3 PF18804.1 OAJ19802.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases TMF_DNA_bd PF12329.8 OAJ19841.1 - 0.19 11.8 15.8 0.16 12.0 9.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Use1 PF09753.9 OAJ19841.1 - 1.9 8.2 18.3 2.6 7.7 18.3 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Cyclin PF08613.11 OAJ19842.1 - 1e-36 126.8 3.8 1.8e-22 80.4 0.0 3.1 3 1 0 3 3 3 2 Cyclin DUF4834 PF16118.5 OAJ19842.1 - 0.75 10.8 3.4 5 8.2 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Pyridoxal_deC PF00282.19 OAJ19843.1 - 6.3e-22 77.8 0.0 8.1e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF2183 PF09949.9 OAJ19848.1 - 3.4e-25 88.2 0.0 6.1e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 OAJ19848.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) AAA PF00004.29 OAJ19849.1 - 3.4e-40 137.5 0.1 9.3e-40 136.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ19849.1 - 2.2e-19 69.1 0.0 4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAJ19849.1 - 2.2e-09 37.0 0.3 5.6e-09 35.7 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ19849.1 - 2.2e-05 24.9 0.2 0.021 15.2 0.0 2.7 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 OAJ19849.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ19849.1 - 0.0013 19.0 0.4 0.065 13.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAJ19849.1 - 0.0013 18.7 0.7 0.0092 16.0 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 OAJ19849.1 - 0.0019 17.7 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.14 OAJ19849.1 - 0.0019 18.3 2.2 0.0086 16.2 0.0 2.7 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 OAJ19849.1 - 0.0072 16.1 1.1 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OAJ19849.1 - 0.011 15.2 0.1 0.046 13.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ19849.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ19849.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAJ19849.1 - 0.059 13.1 0.1 0.17 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain CENP-H PF05837.12 OAJ19849.1 - 0.064 13.7 1.8 0.17 12.3 1.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_14 PF13173.6 OAJ19849.1 - 0.096 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAJ19849.1 - 0.096 13.0 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAJ19849.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ribosomal_S19 PF00203.21 OAJ19849.1 - 0.14 12.1 0.1 22 5.0 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S19 Cutinase PF01083.22 OAJ19850.1 - 9.6e-19 68.0 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 OAJ19850.1 - 0.017 14.8 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 OAJ19850.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain Hydrolase_4 PF12146.8 OAJ19850.1 - 0.71 9.1 5.2 4.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 G-gamma PF00631.22 OAJ19852.1 - 2.1e-21 75.7 0.0 2.3e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain YjbE PF11106.8 OAJ19853.1 - 0.0018 18.4 3.9 0.0033 17.6 3.9 1.5 1 0 0 1 1 1 1 Exopolysaccharide production protein YjbE U71 PF17474.2 OAJ19853.1 - 0.032 14.1 0.0 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Tegument protein UL11 homolog DUF1155 PF06633.11 OAJ19853.1 - 0.16 11.4 0.1 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) Cutinase PF01083.22 OAJ19854.1 - 3.1e-18 66.3 0.0 3.8e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 OAJ19854.1 - 0.0021 18.7 0.3 0.0025 18.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ19854.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Nsp3_PL2pro PF12124.8 OAJ19854.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain YgaB PF14182.6 OAJ19855.1 - 0.2 12.1 1.6 0.37 11.2 1.6 1.6 1 1 0 1 1 1 0 YgaB-like protein Collagen PF01391.18 OAJ19889.1 - 1.2e-18 66.6 77.2 1.5e-10 40.7 36.0 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) THEG4 PF15834.5 OAJ19891.1 - 0.074 13.0 0.1 0.086 12.8 0.1 1.1 1 0 0 1 1 1 0 Testis highly expressed protein 4 RTA1 PF04479.13 OAJ19893.1 - 0.021 14.4 0.4 0.042 13.4 0.4 1.6 1 0 0 1 1 1 0 RTA1 like protein TMEM141 PF15110.6 OAJ19893.1 - 0.055 14.1 1.6 6.2 7.5 0.2 2.5 2 0 0 2 2 2 0 TMEM141 protein family Acetyltransf_1 PF00583.25 OAJ19896.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ19896.1 - 0.011 16.1 0.1 0.039 14.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_S8e PF01201.22 OAJ19897.1 - 1.1e-47 161.6 0.8 1.5e-47 161.2 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Methyltransf_16 PF10294.9 OAJ19898.1 - 1.8e-12 47.3 0.3 2.8e-10 40.2 0.2 3.0 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 OAJ19898.1 - 0.067 12.7 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 OAJ19898.1 - 0.069 12.9 0.0 0.95 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 OAJ19899.1 - 2.1e-26 92.8 0.0 2.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19899.1 - 1.1e-12 47.8 0.0 1.6e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ19899.1 - 1.5e-08 33.9 0.0 2.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sporozoite_P67 PF05642.11 OAJ19899.1 - 0.16 10.0 13.0 0.21 9.6 13.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phage_integrase PF00589.22 OAJ19900.1 - 1.4e-05 24.9 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family GSH_synth_ATP PF03917.17 OAJ19902.1 - 4.1e-111 371.4 0.0 5.5e-110 367.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAJ19902.1 - 3.1e-29 101.4 0.0 4.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Dynamin_M PF01031.20 OAJ19933.1 - 1.2e-99 333.1 0.0 4.7e-99 331.2 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAJ19933.1 - 4.8e-55 186.2 0.1 1.1e-54 185.0 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAJ19933.1 - 9.1e-30 102.7 5.2 9.1e-30 102.7 5.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain IBN_N PF03810.19 OAJ19933.1 - 6.3e-06 26.0 0.1 5.1e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain MMR_HSR1 PF01926.23 OAJ19933.1 - 0.00049 20.2 0.2 0.0026 17.8 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Xpo1 PF08389.12 OAJ19933.1 - 0.053 13.6 0.0 0.23 11.5 0.0 2.1 1 0 0 1 1 1 0 Exportin 1-like protein AAA_15 PF13175.6 OAJ19933.1 - 0.13 11.9 0.2 15 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain PUF PF00806.19 OAJ19934.1 - 6.4e-59 192.5 16.5 6.6e-08 31.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RA PF00788.23 OAJ19934.1 - 0.1 13.2 0.3 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Cys_rich_CPCC PF14206.6 OAJ19935.1 - 0.04 13.7 3.3 0.058 13.2 3.3 1.3 1 0 0 1 1 1 0 Cysteine-rich CPCC Glyco_hydro_79C PF16862.5 OAJ19936.1 - 2.2e-13 51.0 0.0 4.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain HEAT PF02985.22 OAJ19937.1 - 3.5e-05 23.7 15.7 0.28 11.5 0.1 8.6 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 OAJ19937.1 - 0.0023 18.0 0.3 4.6 7.3 0.0 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 OAJ19937.1 - 0.0025 17.0 15.3 0.0043 16.2 0.0 5.5 6 0 0 6 6 6 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 OAJ19937.1 - 0.0064 16.9 15.7 2.1 8.8 0.0 6.9 6 1 0 6 6 6 2 HEAT repeats Arm PF00514.23 OAJ19937.1 - 0.019 15.0 0.2 0.019 15.0 0.2 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 OAJ19937.1 - 0.064 12.4 0.8 22 4.1 0.2 4.3 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 OAJ19937.1 - 0.74 10.4 22.8 1.7 9.2 0.6 7.4 7 0 0 7 7 7 0 HEAT-like repeat CoaE PF01121.20 OAJ19938.1 - 5.4e-58 195.6 0.0 9.4e-58 194.8 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 OAJ19938.1 - 0.0003 21.3 0.0 0.0013 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 OAJ19938.1 - 0.0037 17.4 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 OAJ19938.1 - 0.0038 17.4 0.1 0.019 15.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 OAJ19938.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase-like family T3SS_ExsE PF18286.1 OAJ19938.1 - 0.19 11.7 1.0 0.57 10.2 0.2 2.1 2 0 0 2 2 2 0 Type III secretion system ExsE WW PF00397.26 OAJ19939.1 - 1.6e-08 34.5 2.1 2.6e-08 33.8 2.1 1.4 1 0 0 1 1 1 1 WW domain RhoGEF PF00621.20 OAJ19940.1 - 1e-17 64.9 0.0 1.9e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.20 OAJ19941.1 - 3.5e-20 72.3 0.0 7.7e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ19941.1 - 1.2e-17 64.9 0.0 2.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ19941.1 - 0.0028 17.4 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ19941.1 - 0.0042 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 OAJ19941.1 - 0.092 12.3 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase IPP-2 PF04979.14 OAJ19943.1 - 1.2e-15 58.4 15.1 2.9e-12 47.5 15.1 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Cadherin_4 PF17803.1 OAJ19976.1 - 0.077 13.6 4.3 0.15 12.7 4.3 1.5 1 0 0 1 1 1 0 Bacterial cadherin-like domain Abhydrolase_1 PF00561.20 OAJ19977.1 - 2.2e-16 60.3 0.4 1.8e-12 47.5 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ19977.1 - 8.3e-15 56.0 0.3 1.2e-14 55.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ19977.1 - 5.2e-12 45.5 0.0 1e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ19977.1 - 0.0047 16.6 0.0 0.0064 16.2 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAJ19977.1 - 0.0048 16.7 0.0 0.19 11.5 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 OAJ19977.1 - 0.017 15.0 0.0 0.12 12.2 0.0 2.0 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 OAJ19977.1 - 0.033 14.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase FSH1 PF03959.13 OAJ19977.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) SDA1 PF05285.12 OAJ19978.1 - 0.00028 20.4 8.4 0.00029 20.4 8.4 1.2 1 0 0 1 1 1 1 SDA1 BSP_II PF05432.11 OAJ19978.1 - 0.0012 18.6 12.1 0.002 17.9 12.1 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 OAJ19978.1 - 0.0024 16.2 12.1 0.0025 16.1 12.1 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4637 PF15470.6 OAJ19978.1 - 0.065 13.0 13.3 0.11 12.3 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 OAJ19978.1 - 0.067 12.5 13.6 0.075 12.4 13.6 1.2 1 0 0 1 1 1 0 BUD22 PTPRCAP PF15713.5 OAJ19978.1 - 0.16 12.3 17.7 0.33 11.2 17.7 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mpp10 PF04006.12 OAJ19978.1 - 0.18 10.2 13.4 0.25 9.7 13.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Pox_Ag35 PF03286.14 OAJ19978.1 - 1.6 8.5 9.9 4.1 7.1 10.1 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.14 OAJ19978.1 - 2.1 6.5 13.3 2.7 6.2 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 OAJ19978.1 - 3.7 7.9 5.8 8.5 6.8 5.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 OAJ19978.1 - 4.5 5.9 4.8 5.6 5.6 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 OAJ19978.1 - 6 4.8 26.3 7.7 4.5 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 OAJ19978.1 - 9.5 4.4 6.5 12 4.1 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus His_Phos_1 PF00300.22 OAJ19979.1 - 6.5e-39 133.6 0.0 7.6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.18 OAJ19982.1 - 4.3e-56 189.7 1.4 7.8e-56 188.8 1.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAJ19982.1 - 1.3e-34 118.6 0.0 3.1e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 OAJ19982.1 - 0.0018 18.6 0.2 0.0056 16.9 0.2 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OAJ19982.1 - 0.0023 17.9 0.2 0.0044 17.0 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.11 OAJ19982.1 - 0.0064 16.1 0.2 0.02 14.4 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.14 OAJ19982.1 - 0.02 14.4 0.6 0.082 12.5 0.6 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 OAJ19982.1 - 0.04 14.0 1.1 0.58 10.2 0.2 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OAJ19982.1 - 0.057 13.6 3.2 0.25 11.5 2.2 2.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 OAJ19982.1 - 0.12 12.5 1.9 0.54 10.4 0.9 2.4 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus BRE1 PF08647.11 OAJ19983.1 - 0.0038 17.3 1.1 0.42 10.7 0.1 2.6 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase DUF4746 PF15928.5 OAJ19983.1 - 3.8 6.9 6.8 6.7 6.1 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) KDZ PF18758.1 OAJ19984.1 - 5.2e-07 29.5 0.6 8.4e-07 28.8 0.6 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 OAJ19984.1 - 0.001 18.9 2.3 0.0014 18.5 0.3 2.3 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases START PF01852.19 OAJ19986.1 - 0.0039 16.6 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 START domain CybS PF05328.12 OAJ19987.1 - 7.6e-41 138.9 0.0 1.1e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Ion_trans PF00520.31 OAJ19988.1 - 0.00036 19.8 0.1 0.00059 19.1 0.1 1.3 1 1 0 1 1 1 1 Ion transport protein RTC4 PF14474.6 OAJ19989.1 - 3e-12 46.8 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain SBF PF01758.16 OAJ19989.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Sodium Bile acid symporter family Fcf2 PF08698.11 OAJ20019.1 - 4.4e-18 65.5 0.2 7.4e-17 61.5 0.0 2.6 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing SAP30_Sin3_bdg PF13867.6 OAJ20020.1 - 9e-07 29.1 0.1 6.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CDC45 PF02724.14 OAJ20020.1 - 0.0063 14.9 3.1 0.007 14.7 3.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 OAJ20020.1 - 0.037 13.4 5.2 0.053 12.9 5.2 1.3 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 OAJ20020.1 - 0.073 12.8 8.2 0.21 11.2 2.4 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 OAJ20020.1 - 0.21 9.8 3.6 0.24 9.6 3.6 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 OAJ20020.1 - 1.4 8.7 5.3 0.56 10.0 2.6 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Ldh_1_C PF02866.18 OAJ20022.1 - 2.3e-46 157.8 0.0 5.5e-46 156.6 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAJ20022.1 - 7.1e-44 149.3 0.1 1e-43 148.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAJ20022.1 - 0.0034 16.4 0.0 0.0067 15.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAJ20022.1 - 0.015 15.7 0.2 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAJ20022.1 - 0.044 13.1 0.6 0.89 8.9 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HopA1 PF17914.1 OAJ20022.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 HopA1 effector protein family Sas10 PF09368.10 OAJ20023.1 - 2.1e-26 92.2 4.0 2.1e-26 92.2 4.0 1.9 2 0 0 2 2 2 1 Sas10 C-terminal domain TMEM171 PF15471.6 OAJ20024.1 - 0.035 13.1 0.5 0.053 12.5 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Pkinase PF00069.25 OAJ20025.1 - 4.5e-40 137.7 3.0 4.8e-27 95.0 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20025.1 - 1.6e-26 93.1 0.0 5.3e-18 65.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ20025.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SpoIIP PF07454.11 OAJ20025.1 - 0.34 10.3 3.4 2.6 7.4 3.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) LSM PF01423.22 OAJ20026.1 - 4.7e-17 61.4 0.0 6.8e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain AAA_23 PF13476.6 OAJ20028.1 - 1.6e-16 61.4 56.1 1.6e-16 61.4 56.1 8.3 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.6 OAJ20028.1 - 1.5e-12 47.9 2.8 1.8e-05 24.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAJ20028.1 - 1.4e-11 44.8 0.0 1.4e-11 44.8 0.0 5.3 1 1 3 4 4 2 2 AAA ATPase domain SMC_N PF02463.19 OAJ20028.1 - 4.4e-09 36.1 0.1 4.4e-09 36.1 0.1 3.3 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OAJ20028.1 - 7.8e-06 26.0 0.1 5.9e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OAJ20028.1 - 4.7e-05 23.1 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAJ20028.1 - 0.0015 19.0 0.0 0.0015 19.0 0.0 7.1 3 2 1 5 5 3 1 ABC transporter Roc PF08477.13 OAJ20028.1 - 0.0081 16.4 0.4 0.083 13.1 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 OAJ20028.1 - 0.026 13.2 0.1 0.026 13.2 0.1 7.7 3 1 4 7 7 6 0 AAA domain Spidroin_MaSp PF11260.8 OAJ20028.1 - 0.14 12.5 0.0 0.67 10.3 0.0 2.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 AAA_16 PF13191.6 OAJ20028.1 - 0.4 11.0 0.0 0.4 11.0 0.0 5.2 4 2 1 5 5 3 0 AAA ATPase domain AAA_22 PF13401.6 OAJ20028.1 - 0.63 10.3 0.0 0.63 10.3 0.0 4.0 4 1 0 4 4 3 0 AAA domain AAA_assoc_2 PF16193.5 OAJ20028.1 - 3 8.3 10.7 34 4.8 0.0 5.3 4 0 0 4 4 4 0 AAA C-terminal domain Sas10 PF09368.10 OAJ20030.1 - 1.5e-25 89.4 4.0 1.5e-25 89.4 4.0 2.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAJ20030.1 - 1e-06 29.3 1.5 2.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Pkinase PF00069.25 OAJ20031.1 - 7.1e-68 228.8 0.0 8.8e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20031.1 - 4.6e-30 104.8 0.0 6.5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ20031.1 - 0.0034 17.3 3.5 0.056 13.4 0.1 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ20031.1 - 0.047 12.6 0.0 0.09 11.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAJ20031.1 - 0.079 12.3 0.2 0.24 10.7 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Esterase PF00756.20 OAJ20061.1 - 2e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 OAJ20061.1 - 0.049 13.3 0.0 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DsbC_N PF10411.9 OAJ20061.1 - 0.059 12.8 0.1 0.25 10.8 0.0 2.0 1 1 1 2 2 2 0 Disulfide bond isomerase protein N-terminus DUF4189 PF13827.6 OAJ20061.1 - 0.11 13.1 0.4 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4189) DNA_pol_viral_C PF00336.18 OAJ20062.1 - 0.087 12.2 0.1 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAJ20062.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like PMP1_2 PF08114.11 OAJ20065.1 - 0.16 11.8 0.3 0.28 11.0 0.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Phage_integrase PF00589.22 OAJ20066.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAJ20066.1 - 0.026 14.8 0.0 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain UPF0086 PF01868.16 OAJ20067.1 - 1.7e-16 59.9 0.0 6.3e-16 58.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function UPF0086 PAP_PilO PF06864.12 OAJ20067.1 - 0.13 11.1 2.4 1.6 7.5 0.2 2.5 3 0 0 3 3 3 0 Pilin accessory protein (PilO) Sdh5 PF03937.16 OAJ20068.1 - 1.3e-24 86.0 0.5 7.9e-24 83.4 0.2 2.1 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DUF1674 PF07896.12 OAJ20068.1 - 0.00093 19.6 0.6 0.0045 17.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Pterin_4a PF01329.19 OAJ20069.1 - 1.2e-24 86.2 0.2 1.6e-24 85.8 0.2 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase KSHV_K8 PF07188.11 OAJ20069.1 - 0.066 12.6 0.1 0.066 12.6 0.1 1.1 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein GIY-YIG PF01541.24 OAJ20070.1 - 7.6e-10 38.9 0.0 4e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain 4HBT_3 PF13622.6 OAJ20071.1 - 2.5e-29 103.3 1.6 3.3e-29 102.9 1.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ20071.1 - 0.0008 19.3 0.1 0.0025 17.7 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase Cyclin PF08613.11 OAJ20072.1 - 6.5e-07 29.8 0.0 1.6e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Cyclin DUF1604 PF07713.13 OAJ20073.1 - 8e-35 118.5 8.7 4.3e-34 116.2 8.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAJ20073.1 - 0.00014 21.6 0.4 0.00049 19.9 0.0 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ20073.1 - 0.0049 16.9 4.3 0.008 16.2 0.1 3.1 3 0 0 3 3 3 1 G-patch domain GPI-anchored PF10342.9 OAJ20074.1 - 9.2e-06 26.3 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TubC_N PF18563.1 OAJ20074.1 - 0.15 12.1 0.4 9.1 6.4 0.0 2.8 3 0 0 3 3 3 0 TubC N-terminal docking domain SLD5_C PF16922.5 OAJ20075.1 - 4.1e-13 49.3 0.0 9.6e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAJ20075.1 - 5.7e-05 23.5 0.1 0.00011 22.6 0.1 1.6 1 0 0 1 1 1 1 GINS complex protein ANAPC4_WD40 PF12894.7 OAJ20076.1 - 0.13 12.6 0.5 2.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DDE_Tnp_4 PF13359.6 OAJ20077.1 - 0.00021 21.0 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MIS13 PF08202.11 OAJ20113.1 - 1.6e-17 63.8 0.0 1.8e-14 53.8 0.1 3.4 2 1 0 2 2 2 2 Mis12-Mtw1 protein family Mito_carr PF00153.27 OAJ20114.1 - 2.8e-17 62.4 2.1 1.4e-05 24.9 0.0 5.3 5 0 0 5 5 5 5 Mitochondrial carrier protein TMEM214 PF10151.9 OAJ20114.1 - 0.098 11.1 1.3 0.14 10.6 1.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Phytase-like PF13449.6 OAJ20115.1 - 2.2e-35 123.0 0.3 3.4e-35 122.4 0.3 1.3 1 1 0 1 1 1 1 Esterase-like activity of phytase PQQ PF01011.21 OAJ20115.1 - 0.032 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat HEAT_EZ PF13513.6 OAJ20116.1 - 2.4e-24 85.4 16.2 3.9e-12 46.4 0.0 9.1 8 2 1 9 9 9 4 HEAT-like repeat HEAT PF02985.22 OAJ20116.1 - 1.5e-15 56.0 16.8 0.009 16.2 0.0 9.3 10 0 0 10 10 8 4 HEAT repeat HEAT_2 PF13646.6 OAJ20116.1 - 9e-15 54.8 5.7 0.00018 21.8 0.0 7.5 5 3 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 OAJ20116.1 - 8.9e-11 42.2 0.0 0.0022 18.6 0.0 5.0 3 2 1 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ20116.1 - 4.1e-07 30.2 0.0 0.014 15.4 0.0 4.8 5 2 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAJ20116.1 - 2.5e-06 26.9 9.7 0.0055 15.9 0.1 4.5 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 OAJ20116.1 - 2.1e-05 24.7 0.1 0.00021 21.4 0.0 2.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 OAJ20116.1 - 7e-05 22.7 0.0 0.00028 20.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3437 PF11919.8 OAJ20116.1 - 0.00012 21.9 0.1 0.87 9.5 0.0 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3437) Arm PF00514.23 OAJ20116.1 - 0.0018 18.3 8.6 0.71 10.0 0.0 5.3 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 OAJ20116.1 - 0.0026 17.7 0.1 2.5 8.0 0.0 4.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) ParcG PF10274.9 OAJ20116.1 - 0.0026 17.9 0.1 2.8 8.0 0.0 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein Cnd3 PF12719.7 OAJ20116.1 - 0.023 13.9 0.3 2.1 7.5 0.1 3.4 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain Tti2 PF10521.9 OAJ20116.1 - 0.1 12.1 0.1 8.4 5.8 0.0 3.0 4 0 0 4 4 4 0 Tti2 family Ecm29 PF13001.7 OAJ20116.1 - 0.17 10.5 0.0 5 5.7 0.0 2.7 2 0 0 2 2 2 0 Proteasome stabiliser DUF3295 PF11702.8 OAJ20116.1 - 2.4 7.4 4.5 3.7 6.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TRM PF02005.16 OAJ20117.1 - 6.1e-116 387.7 0.0 2.6e-87 293.5 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF3138 PF11336.8 OAJ20117.1 - 0.26 9.8 3.9 0.43 9.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ferric_reduct PF01794.19 OAJ20118.1 - 2.8e-17 63.0 14.2 5.8e-17 62.0 14.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAJ20118.1 - 6.3e-16 58.4 0.0 2e-10 40.7 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 OAJ20118.1 - 2.1e-11 44.2 0.0 6.9e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Hamartin PF04388.12 OAJ20118.1 - 8.7 4.9 7.9 19 3.8 7.9 1.4 1 0 0 1 1 1 0 Hamartin protein Esterase PF00756.20 OAJ20119.1 - 7.4e-36 124.1 0.0 1e-35 123.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 OAJ20119.1 - 0.064 12.2 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Gti1_Pac2 PF09729.9 OAJ20120.1 - 1.6e-27 96.7 2.6 3.3e-25 89.2 0.1 6.3 5 3 1 6 6 6 3 Gti1/Pac2 family Ric8 PF10165.9 OAJ20122.1 - 4.3e-74 250.2 4.1 1.2e-43 149.9 0.0 2.2 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn U1snRNP70_N PF12220.8 OAJ20122.1 - 0.33 11.6 3.5 0.74 10.5 2.1 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Tom5 PF10642.9 OAJ20155.1 - 0.18 11.9 4.7 2.6 8.2 1.5 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase NIF PF03031.18 OAJ20157.1 - 4.1e-40 137.1 0.0 6e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acyltransferase PF01553.21 OAJ20157.1 - 2.1e-22 79.2 0.0 3.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HORMA PF02301.18 OAJ20158.1 - 3.2e-27 95.5 0.0 3.7e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain AAA_22 PF13401.6 OAJ20159.1 - 4e-10 40.1 0.0 1.4e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAJ20159.1 - 2.5e-06 27.9 0.4 0.0049 17.3 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ20159.1 - 4.7e-05 23.8 0.1 0.00025 21.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 OAJ20159.1 - 0.00038 20.5 0.1 0.0009 19.3 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_33 PF13671.6 OAJ20159.1 - 0.0068 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ20159.1 - 0.01 15.8 0.2 0.077 12.9 0.2 2.3 1 1 0 1 1 1 0 NACHT domain TniB PF05621.11 OAJ20159.1 - 0.012 15.0 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OAJ20159.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 OAJ20159.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF5510 PF17629.2 OAJ20160.1 - 0.026 14.4 1.3 0.041 13.8 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5510) tRNA-synt_2b PF00587.25 OAJ20161.1 - 2.2e-40 138.5 0.0 4e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ20161.1 - 3e-11 43.3 0.1 4.1e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Anticodon binding domain DEAD PF00270.29 OAJ20162.1 - 4.7e-06 26.5 0.0 1.6e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ20162.1 - 0.0021 18.1 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 OAJ20162.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Helicase Vps5 PF09325.10 OAJ20164.1 - 0.074 12.6 2.7 0.073 12.6 0.9 1.8 2 0 0 2 2 2 0 Vps5 C terminal like MFS_1 PF07690.16 OAJ20165.1 - 7.8e-07 28.3 13.4 0.00064 18.8 0.6 4.2 4 0 0 4 4 4 2 Major Facilitator Superfamily BUD22 PF09073.10 OAJ20165.1 - 0.0017 17.8 3.6 0.64 9.3 0.3 2.4 2 0 0 2 2 2 2 BUD22 FAM176 PF14851.6 OAJ20165.1 - 0.011 15.4 0.7 0.91 9.2 0.3 3.4 3 0 0 3 3 3 0 FAM176 family Sugar_tr PF00083.24 OAJ20165.1 - 0.02 13.8 0.7 0.93 8.3 0.5 3.2 4 1 1 5 5 5 0 Sugar (and other) transporter Tub_N PF16322.5 OAJ20165.1 - 0.25 11.7 4.9 29 5.0 3.4 2.8 2 1 0 2 2 2 0 Tubby N-terminal TRAP_alpha PF03896.16 OAJ20165.1 - 0.32 10.2 2.0 0.85 8.8 0.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Orf78 PF06024.12 OAJ20165.1 - 0.38 11.1 1.5 4.5 7.6 0.5 3.0 3 0 0 3 3 3 0 Orf78 (ac78) Sigma70_ner PF04546.13 OAJ20165.1 - 5.8 6.7 7.5 2.8 7.8 2.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region UbiA PF01040.18 OAJ20166.1 - 3e-50 170.9 24.5 3.8e-48 164.0 24.5 2.2 1 1 0 1 1 1 1 UbiA prenyltransferase family TIP49_C PF17856.1 OAJ20166.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 AAA-lid domain Glucosamine_iso PF01182.20 OAJ20167.1 - 3.6e-75 252.7 0.0 4.4e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF202 PF02656.15 OAJ20168.1 - 3.1e-05 24.3 4.9 5.8e-05 23.5 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TC1 PF15063.6 OAJ20168.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Thyroid cancer protein 1 Pex14_N PF04695.13 OAJ20168.1 - 0.054 14.1 11.4 0.13 12.9 2.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.15 OAJ20168.1 - 0.15 12.7 2.9 0.2 12.3 0.0 2.0 1 1 1 2 2 2 0 Ctr copper transporter family DUF4834 PF16118.5 OAJ20168.1 - 0.16 12.9 0.2 37 5.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Chitin_synth_2 PF03142.15 OAJ20169.1 - 1.3e-236 786.3 0.0 1.8e-236 785.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 OAJ20169.1 - 2.9e-11 43.7 0.4 1.6e-10 41.3 0.2 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ20169.1 - 2.9e-10 40.4 10.8 2.9e-10 40.4 10.8 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF3149 PF11346.8 OAJ20169.1 - 0.4 10.3 4.8 1.6 8.4 4.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) GMC_oxred_N PF00732.19 OAJ20199.1 - 7.6e-60 202.8 0.0 9.9e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ20199.1 - 2e-27 96.5 0.0 3.9e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ20199.1 - 1.1e-06 28.8 0.0 1.1e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ20199.1 - 2e-05 24.4 0.3 4.8e-05 23.1 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ20199.1 - 2.5e-05 23.6 0.0 0.00013 21.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ20199.1 - 3.4e-05 23.1 0.0 6.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAJ20199.1 - 5.6e-05 22.5 0.1 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAJ20199.1 - 0.0086 15.3 0.1 0.019 14.2 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ20199.1 - 0.071 11.8 0.4 0.19 10.4 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAJ20199.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Alpha_GJ PF03229.13 OAJ20199.1 - 8.2 7.0 16.3 7.1 7.2 3.3 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Iso_dh PF00180.20 OAJ20200.1 - 1.2e-102 343.6 0.0 1.7e-102 343.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhzC-PhzF PF02567.16 OAJ20201.1 - 1.4e-37 129.7 0.0 1.7e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 OAJ20201.1 - 0.0028 16.8 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.18 OAJ20202.1 - 2.2e-09 36.8 0.1 3.3e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ20202.1 - 4.2e-07 30.0 10.0 6.9e-07 29.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 OAJ20202.1 - 0.77 10.4 8.1 2.2 8.9 8.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein SRP68 PF16969.5 OAJ20203.1 - 3e-59 201.5 32.3 7.1e-49 167.3 13.4 3.6 3 1 0 3 3 3 2 RNA-binding signal recognition particle 68 HSP70 PF00012.20 OAJ20204.1 - 5e-256 850.6 14.3 5.7e-256 850.4 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ20204.1 - 5.7e-19 68.1 0.4 4.9e-17 61.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OAJ20204.1 - 0.00067 18.8 0.5 0.02 13.9 0.3 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 OAJ20204.1 - 0.023 14.5 0.0 0.084 12.6 0.0 1.9 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OAJ20204.1 - 0.038 14.4 4.5 31 5.1 0.3 3.5 3 1 0 3 3 3 0 Cell division protein FtsA Zincin_2 PF10103.9 OAJ20204.1 - 0.076 12.3 0.1 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Zincin-like metallopeptidase Hydantoinase_A PF01968.18 OAJ20204.1 - 0.17 11.1 1.9 0.67 9.2 0.2 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2680 PF10925.8 OAJ20204.1 - 1.9 8.5 4.3 7.1 6.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Spectrin PF00435.21 OAJ20204.1 - 3.1 8.3 8.0 24 5.5 1.4 2.7 1 1 0 1 1 1 0 Spectrin repeat Seryl_tRNA_N PF02403.22 OAJ20204.1 - 5.5 7.3 14.7 3.3 8.0 6.3 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TRAF_BIRC3_bd PF16673.5 OAJ20204.1 - 8.5 6.3 7.4 6.3 6.7 0.4 3.5 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain MAD PF05557.13 OAJ20205.1 - 0.47 8.7 16.9 0.014 13.8 10.0 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein HAUS-augmin3 PF14932.6 OAJ20205.1 - 0.85 9.1 5.2 2 7.9 4.4 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Bromodomain PF00439.25 OAJ20206.1 - 5.6e-30 103.2 1.9 2e-13 50.2 0.1 3.5 3 1 0 3 3 3 2 Bromodomain BET PF17035.5 OAJ20206.1 - 2e-18 66.3 0.1 3.6e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Abhydro_lipase PF04083.16 OAJ20207.1 - 1e-13 50.6 0.0 2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAJ20207.1 - 1.3e-06 28.2 0.3 2.1e-06 27.6 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ20207.1 - 0.00031 20.1 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 F-box-like PF12937.7 OAJ20208.1 - 7.5e-09 35.3 1.6 1.8e-08 34.2 1.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ20208.1 - 5.3e-07 29.3 1.2 9.2e-07 28.6 1.2 1.4 1 0 0 1 1 1 1 F-box domain HsbA PF12296.8 OAJ20209.1 - 1e-19 71.1 15.6 1e-19 71.1 15.6 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A DUF1326 PF07040.11 OAJ20209.1 - 0.036 14.1 0.6 0.055 13.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1326) Baculo_PEP_C PF04513.12 OAJ20209.1 - 0.21 11.6 7.6 0.26 11.3 7.3 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.22 OAJ20242.1 - 0.001 18.9 0.0 0.2 11.5 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 OAJ20242.1 - 0.12 10.6 32.9 0.2 9.8 9.9 2.0 2 0 0 2 2 2 0 Nop14-like family RhoGEF PF00621.20 OAJ20243.1 - 6e-12 46.2 0.0 4.6e-08 33.5 0.0 2.8 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.29 OAJ20243.1 - 0.0032 17.9 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 PH domain UBA2_C PF16195.5 OAJ20244.1 - 0.031 15.0 0.3 0.084 13.6 0.3 1.7 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Sulfate_transp PF00916.20 OAJ20245.1 - 7.1e-38 130.3 14.2 1e-37 129.8 14.2 1.2 1 0 0 1 1 1 1 Sulfate permease family Complex1_LYR PF05347.15 OAJ20247.1 - 2.1e-07 30.9 5.9 3.9e-07 30.0 5.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ORC6 PF05460.13 OAJ20247.1 - 0.07 12.4 0.2 0.097 11.9 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MWFE PF15879.5 OAJ20248.1 - 8.7e-25 86.7 0.6 1.1e-24 86.3 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DUF4405 PF14358.6 OAJ20248.1 - 0.13 12.9 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) UPF0052 PF01933.18 OAJ20249.1 - 2.1e-39 135.5 0.0 2.3e-24 86.1 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 TFIIA PF03153.13 OAJ20249.1 - 0.0013 18.8 3.9 0.002 18.2 3.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Drc1-Sld2 PF11719.8 OAJ20249.1 - 3.3 7.2 10.2 1.3 8.5 7.8 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein GST_C_3 PF14497.6 OAJ20250.1 - 7.2e-26 90.3 0.1 1.4e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ20250.1 - 8.5e-06 25.9 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ20250.1 - 0.00027 20.9 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CDC45 PF02724.14 OAJ20251.1 - 0.0016 16.9 0.7 0.0016 16.9 0.7 1.7 2 0 0 2 2 2 1 CDC45-like protein YL1 PF05764.13 OAJ20251.1 - 0.0045 17.1 0.4 0.0045 17.1 0.4 1.8 2 0 0 2 2 2 1 YL1 nuclear protein Sulfate_transp PF00916.20 OAJ20252.1 - 1e-12 47.6 0.7 1e-12 47.6 0.7 1.4 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 OAJ20252.1 - 3e-11 43.2 0.0 6.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAJ20252.1 - 2.3e-10 40.1 0.1 5.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain Cullin PF00888.22 OAJ20287.1 - 0.03 12.9 0.0 0.12 11.0 0.0 1.8 1 1 0 1 1 1 0 Cullin family TAF4 PF05236.14 OAJ20287.1 - 0.14 11.8 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SYF2 PF08231.12 OAJ20288.1 - 2.4e-46 158.0 6.8 2.4e-46 158.0 6.8 2.0 2 0 0 2 2 2 1 SYF2 splicing factor WD40 PF00400.32 OAJ20288.1 - 0.074 13.9 0.4 2.1 9.3 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat COQ7 PF03232.13 OAJ20290.1 - 2e-67 226.3 0.1 2.7e-67 225.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin PF00210.24 OAJ20290.1 - 0.0088 16.0 0.2 0.24 11.3 0.0 2.3 2 0 0 2 2 2 1 Ferritin-like domain Rubrerythrin PF02915.17 OAJ20290.1 - 0.04 14.3 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Rubrerythrin DUF3446 PF11928.8 OAJ20290.1 - 0.074 13.4 0.3 0.074 13.4 0.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Prenyltrans PF00432.21 OAJ20291.1 - 1.5e-28 98.2 10.1 1.3e-07 31.2 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OAJ20291.1 - 0.00071 18.8 0.0 0.62 9.1 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain AKAP2_C PF15304.6 OAJ20291.1 - 0.0046 16.3 0.2 0.0046 16.3 0.2 1.9 3 0 0 3 3 3 1 A-kinase anchor protein 2 C-terminus Response_reg PF00072.24 OAJ20292.1 - 2.3e-07 31.0 0.0 2.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain MRP-L46 PF11788.8 OAJ20293.1 - 6.8e-19 68.8 0.3 2.8e-18 66.8 0.1 2.2 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 YjfB_motility PF14070.6 OAJ20293.1 - 0.14 12.3 6.8 0.29 11.3 0.0 2.6 2 0 0 2 2 2 0 Putative motility protein Tautomerase PF01361.21 OAJ20293.1 - 0.35 10.8 1.4 7.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme Symplekin_C PF12295.8 OAJ20294.1 - 4.8e-55 186.5 0.4 1e-54 185.5 0.1 1.7 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 OAJ20294.1 - 4.8e-35 121.2 0.1 9.9e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 OAJ20294.1 - 0.0088 16.4 1.8 0.85 10.1 0.1 3.8 3 0 0 3 3 3 1 HEAT repeats PAC4 PF16093.5 OAJ20295.1 - 2.8e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 zf-H2C2_2 PF13465.6 OAJ20296.1 - 4.2e-09 36.4 5.8 1.7e-08 34.5 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAJ20296.1 - 3.2e-05 24.2 14.0 0.00011 22.5 0.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAJ20296.1 - 4e-05 24.2 11.4 0.15 12.7 1.1 3.6 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAJ20296.1 - 0.0014 19.3 0.9 0.0014 19.3 0.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ20296.1 - 0.0015 18.4 0.5 0.0015 18.4 0.5 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAJ20296.1 - 0.43 10.7 1.5 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf_ZIC PF18366.1 OAJ20296.1 - 8.9 6.5 6.6 6 7.1 0.3 3.0 2 1 1 3 3 3 0 Zic proteins zinc finger domain DUF1746 PF08508.10 OAJ20297.1 - 1.7e-16 60.6 2.0 3.5e-16 59.6 2.0 1.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DIOX_N PF14226.6 OAJ20298.1 - 1.6e-21 77.2 0.0 2.5e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAJ20298.1 - 5.5e-18 65.3 0.0 9.2e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 OAJ20299.1 - 6.8e-43 146.5 0.0 1.2e-20 74.4 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAJ20299.1 - 4.4e-24 84.3 2.3 4.4e-24 84.3 2.3 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OAJ20299.1 - 3.7e-13 49.4 0.1 7.6e-06 25.5 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ20299.1 - 6.4e-13 49.2 5.3 0.0026 17.6 0.3 4.6 4 1 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ20299.1 - 1.3e-06 28.0 0.1 0.012 15.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ20299.1 - 6.7e-06 26.2 0.6 0.021 14.9 0.1 3.2 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ20299.1 - 1.5e-05 25.3 0.1 0.13 12.5 0.1 3.3 4 1 0 4 4 2 2 AAA domain DUF87 PF01935.17 OAJ20299.1 - 0.00023 21.4 2.5 0.036 14.2 0.0 3.5 3 1 0 3 3 3 1 Helicase HerA, central domain NACHT PF05729.12 OAJ20299.1 - 0.00027 20.9 0.4 0.24 11.3 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_33 PF13671.6 OAJ20299.1 - 0.00037 20.7 1.1 1.6 8.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OAJ20299.1 - 0.00041 20.3 0.1 0.16 11.8 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 OAJ20299.1 - 0.00041 20.6 0.8 1.1 9.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 OAJ20299.1 - 0.00073 19.3 0.0 0.44 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ20299.1 - 0.0009 19.6 0.0 0.077 13.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 OAJ20299.1 - 0.0022 17.8 3.5 0.34 10.6 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 OAJ20299.1 - 0.0073 16.8 8.8 0.24 11.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 OAJ20299.1 - 0.0098 15.9 0.0 3.9 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAJ20299.1 - 0.014 14.4 0.0 3 6.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OAJ20299.1 - 0.019 15.3 5.2 1.5 9.2 0.0 3.4 4 0 0 4 4 3 0 AAA ATPase domain AAA_18 PF13238.6 OAJ20299.1 - 0.03 14.9 0.1 1 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF287 PF03384.14 OAJ20299.1 - 0.042 14.2 0.3 0.19 12.1 0.1 2.2 2 0 0 2 2 1 0 Drosophila protein of unknown function, DUF287 T2SSE PF00437.20 OAJ20299.1 - 0.049 12.7 0.0 0.86 8.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAJ20299.1 - 0.049 13.0 0.0 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 OAJ20299.1 - 0.054 13.4 0.0 9.5 6.1 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 OAJ20299.1 - 0.057 12.9 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 OAJ20299.1 - 0.068 12.8 0.1 12 5.4 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OAJ20299.1 - 0.08 12.5 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OAJ20299.1 - 0.15 11.8 5.8 0.76 9.5 0.2 3.8 3 2 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 OAJ20299.1 - 0.37 10.8 4.4 1.7 8.7 0.0 3.2 4 0 0 4 4 3 0 Dynamin family TFIID_30kDa PF03540.13 OAJ20329.1 - 9.3e-25 86.3 0.0 1.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.28 OAJ20329.1 - 5.5e-05 23.5 0.0 0.0091 16.4 0.0 2.5 2 0 0 2 2 2 1 CBS domain Ribosomal_60s PF00428.19 OAJ20329.1 - 0.24 12.0 0.1 0.24 12.0 0.1 3.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein FoP_duplication PF13865.6 OAJ20329.1 - 2.9 8.5 12.2 0.1 13.2 2.8 2.6 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 PGK PF00162.19 OAJ20332.1 - 1.9e-148 494.5 3.5 2.1e-148 494.3 3.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NTF2 PF02136.20 OAJ20333.1 - 9.6e-33 113.3 0.1 1.2e-32 113.0 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAJ20333.1 - 0.029 14.8 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Glutaredoxin PF00462.24 OAJ20334.1 - 7e-19 67.8 0.0 1.2e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAJ20334.1 - 1.9e-16 59.9 0.0 3.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ20334.1 - 5.6e-05 23.4 0.1 0.044 14.1 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ20334.1 - 0.0004 20.8 0.0 0.0024 18.3 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 OAJ20334.1 - 0.0023 17.8 0.0 0.011 15.6 0.0 2.0 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DUF3246 PF11596.8 OAJ20334.1 - 0.01 15.3 1.8 0.015 14.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) OST3_OST6 PF04756.13 OAJ20334.1 - 0.062 12.6 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HMG_box PF00505.19 OAJ20335.1 - 4.5e-10 39.8 1.2 8.5e-10 38.9 1.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 OAJ20335.1 - 0.00089 18.6 0.2 0.0015 17.8 0.2 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box TPT PF03151.16 OAJ20336.1 - 4e-45 154.4 13.9 5.9e-45 153.8 12.4 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ20336.1 - 5.1e-10 39.7 25.8 3.3e-06 27.3 11.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAJ20336.1 - 9e-06 25.1 13.2 1.5e-05 24.3 13.2 1.3 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 OAJ20336.1 - 0.24 12.1 9.2 0.038 14.6 4.9 1.9 2 0 0 2 2 2 0 Small Multidrug Resistance protein A_deaminase PF00962.22 OAJ20337.1 - 1.1e-118 396.3 0.1 1.8e-118 395.6 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase TFIIA PF03153.13 OAJ20337.1 - 0.9 9.5 14.1 1.5 8.8 14.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 4HBT PF03061.22 OAJ20338.1 - 1.8e-07 31.4 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily PX PF00787.24 OAJ20339.1 - 2.1e-11 43.8 0.0 4.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 PX domain SpoIIIAH PF12685.7 OAJ20339.1 - 0.27 11.0 1.1 0.8 9.5 0.5 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein Pinin_SDK_N PF04697.13 OAJ20339.1 - 2.3 8.8 7.1 0.15 12.7 0.3 2.7 3 0 0 3 3 3 0 pinin/SDK conserved region DEAD PF00270.29 OAJ20340.1 - 6.6e-44 149.8 0.5 1.1e-43 149.1 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20340.1 - 3.1e-34 117.6 0.1 1.4e-33 115.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ20340.1 - 0.00048 20.2 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ20340.1 - 0.0006 20.2 0.1 0.024 15.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ20340.1 - 0.0035 17.1 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 OAJ20340.1 - 0.044 12.6 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 OAJ20340.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 OAJ20340.1 - 0.073 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SF3A3 PF16837.5 OAJ20341.1 - 1.2e-23 83.5 0.6 3.5e-23 81.9 0.2 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 OAJ20341.1 - 0.00038 20.3 0.1 0.001 18.9 0.1 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 OAJ20341.1 - 0.00045 20.5 0.1 0.001 19.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.8 OAJ20341.1 - 0.00087 19.1 1.6 0.013 15.3 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.8 OAJ20341.1 - 0.0033 17.7 0.1 0.0098 16.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding NIF PF03031.18 OAJ20342.1 - 5.6e-51 172.4 0.0 2.4e-50 170.3 0.0 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 OAJ20342.1 - 0.13 11.0 1.1 0.15 10.7 1.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Baculo_PP31 PF05311.11 OAJ20342.1 - 1.1 8.7 5.4 1.5 8.3 5.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NPR3 PF03666.13 OAJ20342.1 - 1.2 7.9 9.0 1.5 7.5 9.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 OAJ20342.1 - 1.3 8.2 15.0 1.5 8.0 15.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PPP4R2 PF09184.11 OAJ20342.1 - 3.2 7.3 13.0 4.5 6.8 13.0 1.2 1 0 0 1 1 1 0 PPP4R2 Spem1 PF15670.5 OAJ20342.1 - 5.1 6.6 12.0 7.6 6.0 12.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 FAM60A PF15396.6 OAJ20342.1 - 5.4 7.0 8.3 8.8 6.3 8.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Afi1 PF07792.12 OAJ20342.1 - 6.3 7.3 11.7 11 6.5 11.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Homoserine_dh PF00742.19 OAJ20343.1 - 2.3e-46 157.9 0.0 3.6e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAJ20343.1 - 1.6e-16 61.0 0.1 3e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Evr1_Alr PF04777.13 OAJ20382.1 - 2.2e-27 95.4 0.1 3.2e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF4585 PF15232.6 OAJ20382.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) RNA_pol_Rpb1_1 PF04997.12 OAJ20383.1 - 3.4e-106 355.1 0.0 5e-106 354.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OAJ20383.1 - 1.4e-100 336.2 0.1 1.9e-100 335.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAJ20383.1 - 1.5e-73 246.5 0.0 2.7e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OAJ20383.1 - 6.1e-59 199.1 0.1 9.8e-59 198.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OAJ20383.1 - 4.4e-45 153.4 0.0 9e-45 152.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAJ20383.1 - 1.4e-43 148.1 0.4 2.6e-43 147.2 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAJ20383.1 - 2.2e-36 124.1 0.1 5.1e-36 122.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAJ20383.1 - 2.5e-24 84.3 234.4 0.005 17.1 10.0 16.0 11 3 6 18 18 18 16 RNA polymerase Rpb1 C-terminal repeat PCI PF01399.27 OAJ20384.1 - 1.8e-20 73.4 0.0 4.6e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 OAJ20384.1 - 1.7e-11 44.0 0.1 5e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5588 PF17826.1 OAJ20384.1 - 0.00037 19.5 0.2 0.00054 18.9 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TonB_N PF16031.5 OAJ20384.1 - 0.0029 18.1 6.3 0.0049 17.4 6.3 1.3 1 0 0 1 1 1 1 TonB polyproline region TPR_14 PF13428.6 OAJ20384.1 - 0.14 13.1 4.2 10 7.3 2.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ20384.1 - 0.24 11.7 2.7 1.8 9.0 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ20384.1 - 0.56 11.0 3.6 18 6.4 2.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ20384.1 - 0.59 10.7 5.0 6.4 7.4 1.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RrnaAD PF00398.20 OAJ20385.1 - 1.1e-15 57.4 0.0 2.8e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase AT_hook PF02178.19 OAJ20385.1 - 0.012 15.3 16.8 0.13 12.2 4.1 2.7 2 0 0 2 2 2 0 AT hook motif ABC_tran PF00005.27 OAJ20386.1 - 9.2e-36 123.4 0.1 8.2e-18 65.2 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 OAJ20386.1 - 1.7e-14 53.3 5.7 4.4e-14 52.0 5.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OAJ20386.1 - 2e-09 37.2 5.1 0.001 18.6 1.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ20386.1 - 5.7e-09 36.2 3.9 0.17 11.7 0.8 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 OAJ20386.1 - 2.5e-07 30.2 3.3 2.5e-07 30.2 3.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 OAJ20386.1 - 4.1e-06 26.7 1.6 0.052 13.2 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OAJ20386.1 - 1.1e-05 25.9 0.0 0.042 14.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAJ20386.1 - 1.2e-05 25.3 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Fer4_10 PF13237.6 OAJ20386.1 - 5.7e-05 23.1 8.9 0.00071 19.6 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.6 OAJ20386.1 - 5.9e-05 23.5 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Fer4_6 PF12837.7 OAJ20386.1 - 7.3e-05 22.7 11.5 9.4e-05 22.3 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 OAJ20386.1 - 0.00011 22.4 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ20386.1 - 0.00016 21.4 0.2 0.51 10.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_7 PF12838.7 OAJ20386.1 - 0.00043 20.8 8.7 0.0014 19.2 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_24 PF13479.6 OAJ20386.1 - 0.00081 19.2 0.1 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ20386.1 - 0.00087 19.5 0.3 0.5 10.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OAJ20386.1 - 0.0011 18.9 1.1 0.098 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 OAJ20386.1 - 0.0013 18.3 0.9 0.015 14.9 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 OAJ20386.1 - 0.0016 19.0 5.4 0.035 14.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ20386.1 - 0.0016 18.8 0.0 0.4 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.22 OAJ20386.1 - 0.0022 17.7 1.3 0.27 10.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 OAJ20386.1 - 0.0029 17.6 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_2 PF12797.7 OAJ20386.1 - 0.0037 17.3 1.3 0.0037 17.3 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 OAJ20386.1 - 0.0038 17.2 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_21 PF14697.6 OAJ20386.1 - 0.0049 17.0 12.9 0.011 15.8 12.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.11 OAJ20386.1 - 0.0051 16.6 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 1 Virulence-associated protein E NB-ARC PF00931.22 OAJ20386.1 - 0.0067 15.7 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 OAJ20386.1 - 0.0077 16.5 0.0 5.7 7.2 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 OAJ20386.1 - 0.0082 17.1 0.3 0.0082 17.1 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_28 PF13521.6 OAJ20386.1 - 0.01 16.1 2.0 1.5 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 OAJ20386.1 - 0.01 16.4 0.1 3.1 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 OAJ20386.1 - 0.012 15.7 11.8 0.042 14.0 12.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ20386.1 - 0.022 15.2 4.4 0.08 13.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OAJ20386.1 - 0.022 15.3 0.1 0.022 15.3 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 OAJ20386.1 - 0.027 14.5 0.4 13 5.9 0.1 3.2 2 1 1 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 OAJ20386.1 - 0.047 13.4 0.4 9 5.9 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase AAA_30 PF13604.6 OAJ20386.1 - 0.12 12.1 1.6 4.4 7.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OAJ20386.1 - 0.23 11.4 0.9 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OAJ20386.1 - 0.37 10.9 2.5 22 5.1 0.1 3.0 3 1 0 3 3 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 OAJ20386.1 - 0.7 9.8 2.6 6.7 6.6 0.1 3.2 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 OAJ20386.1 - 2.5 8.8 14.6 0.42 11.2 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain LSM PF01423.22 OAJ20387.1 - 5.1e-11 42.1 0.0 8.5e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 LSM domain DUF5440 PF17509.2 OAJ20387.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5440) Hep_59 PF07052.11 OAJ20388.1 - 2.4e-27 95.8 0.6 2.4e-27 95.8 0.6 3.0 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 HTH_23 PF13384.6 OAJ20389.1 - 0.00017 21.3 0.1 0.00083 19.1 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain T3SS_needle_F PF09392.10 OAJ20389.1 - 0.0039 17.3 0.1 0.33 11.2 0.2 2.8 3 0 0 3 3 3 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CPSase_L_D3 PF02787.19 OAJ20389.1 - 0.036 14.4 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_7 PF02796.15 OAJ20389.1 - 0.11 12.6 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Sedlin_N PF04628.13 OAJ20391.1 - 4.4e-33 114.2 0.0 2.4e-29 102.1 0.0 2.0 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAJ20391.1 - 3.6e-05 23.7 0.0 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sporozoite_P67 PF05642.11 OAJ20391.1 - 0.68 8.0 6.1 0.79 7.7 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF508 PF04370.12 OAJ20391.1 - 4.5 7.0 7.1 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) FA_hydroxylase PF04116.13 OAJ20392.1 - 4.1e-19 69.2 2.1 4.1e-19 69.2 2.1 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TraG_N PF07916.11 OAJ20393.1 - 2.8 6.7 5.3 2.2 7.0 2.8 1.8 1 1 1 2 2 2 0 TraG-like protein, N-terminal region Band_7 PF01145.25 OAJ20393.1 - 2.8 7.9 25.6 20 5.1 0.0 4.2 2 1 0 2 2 2 0 SPFH domain / Band 7 family Cutinase PF01083.22 OAJ20427.1 - 3.5e-24 85.7 0.0 4.1e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ20427.1 - 0.0057 16.2 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 OAJ20427.1 - 0.027 14.6 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_8 PF06259.12 OAJ20427.1 - 0.03 14.0 0.1 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_2 PF02230.16 OAJ20427.1 - 0.053 13.3 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 OAJ20427.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.16 OAJ20428.1 - 2.4e-40 138.5 48.3 5.3e-26 91.4 18.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily AMP-binding PF00501.28 OAJ20430.1 - 5.7e-48 163.5 0.0 8.1e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAJ20430.1 - 1.2e-11 44.4 1.0 1.6e-11 44.0 0.2 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAJ20430.1 - 0.0022 18.9 0.0 0.0048 17.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tim17 PF02466.19 OAJ20431.1 - 2.2e-25 89.2 6.1 2.2e-25 89.2 6.1 1.8 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family FxsA PF04186.13 OAJ20431.1 - 4.9 7.3 6.7 0.93 9.6 1.1 2.3 1 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Golgin_A5 PF09787.9 OAJ20432.1 - 0.0037 16.8 8.0 0.0037 16.8 8.0 7.0 2 1 6 8 8 8 3 Golgin subfamily A member 5 SNARE PF05739.19 OAJ20432.1 - 0.61 10.1 2.5 1.4 9.0 0.4 2.9 2 0 0 2 2 2 0 SNARE domain FAM184 PF15665.5 OAJ20432.1 - 0.83 9.4 132.7 0.11 12.3 26.9 6.0 1 1 4 5 5 5 0 Family with sequence similarity 184, A and B Sugar_tr PF00083.24 OAJ20433.1 - 1e-32 113.6 21.0 9.5e-32 110.4 21.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20433.1 - 2.9e-28 98.8 35.8 2.9e-28 98.8 35.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ20434.1 - 3.4e-34 118.5 22.1 2.6e-33 115.6 22.1 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20434.1 - 2.1e-24 86.1 33.4 2.1e-24 86.1 33.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF347 PF03988.12 OAJ20434.1 - 0.93 9.7 0.0 0.93 9.7 0.0 4.2 4 1 0 4 4 4 0 Repeat of Unknown Function (DUF347) Cutinase PF01083.22 OAJ20436.1 - 1.9e-20 73.6 0.0 2.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ20436.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Pkinase PF00069.25 OAJ20438.1 - 8.6e-59 199.0 0.0 3.4e-58 197.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 OAJ20438.1 - 1e-39 136.4 0.1 3.6e-35 121.6 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 OAJ20438.1 - 1.7e-38 132.4 0.0 4.2e-38 131.1 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ20438.1 - 0.0047 16.3 0.0 2.8 7.2 0.0 3.0 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAJ20438.1 - 0.0077 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ20438.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tom22 PF04281.13 OAJ20439.1 - 0.27 11.0 0.0 39 4.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 NTF2 PF02136.20 OAJ20484.1 - 5.6e-30 104.4 0.0 8.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OAJ20484.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 OAJ20484.1 - 0.0032 16.7 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) RRM_occluded PF16842.5 OAJ20484.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif EF-hand_1 PF00036.32 OAJ20485.1 - 5.9e-42 138.1 13.0 1.5e-10 39.8 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAJ20485.1 - 4e-36 123.3 2.7 2.5e-18 66.3 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAJ20485.1 - 1.4e-31 105.7 7.4 1.8e-09 36.8 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ20485.1 - 3.8e-31 106.7 10.9 1.5e-14 53.5 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OAJ20485.1 - 6.1e-27 91.9 9.3 9.9e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAJ20485.1 - 2.6e-16 59.7 0.2 2.1e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAJ20485.1 - 3.8e-10 39.7 0.6 3.5e-05 23.7 0.3 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAJ20485.1 - 1.7e-08 34.8 0.0 0.00092 19.5 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAJ20485.1 - 3.5e-06 27.0 1.7 0.041 13.9 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OAJ20485.1 - 6.4e-06 27.0 0.0 0.0051 17.7 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OAJ20485.1 - 0.00013 22.1 5.6 0.017 15.3 0.7 3.1 1 1 3 4 4 4 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 OAJ20485.1 - 0.00014 21.9 0.3 0.00051 20.1 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 OAJ20485.1 - 0.00068 19.3 1.2 0.00079 19.1 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 OAJ20485.1 - 0.0013 18.7 1.5 0.47 10.4 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein Poly_export PF02563.16 OAJ20485.1 - 0.0034 17.6 0.1 0.69 10.2 0.0 2.9 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 OAJ20485.1 - 0.0037 17.7 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 OAJ20485.1 - 0.0052 16.7 0.2 1.3 9.0 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.10 OAJ20485.1 - 0.0075 16.4 0.2 0.12 12.5 0.1 2.2 2 1 0 2 2 2 1 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.16 OAJ20485.1 - 0.0091 16.3 0.3 3.8 7.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 OAJ20485.1 - 0.013 14.1 0.0 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 OAJ20485.1 - 0.025 14.6 0.5 18 5.5 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 dCache_2 PF08269.11 OAJ20485.1 - 0.034 13.3 0.1 0.61 9.2 0.1 2.2 1 1 0 1 1 1 0 Cache domain SurA_N_2 PF13623.6 OAJ20485.1 - 0.039 13.8 0.6 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 OAJ20485.1 - 0.061 13.7 0.1 15 6.0 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 OAJ20485.1 - 0.071 13.3 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Fe_hyd_lg_C PF02906.14 OAJ20485.1 - 0.076 12.7 0.2 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RuvA_C PF07499.13 OAJ20485.1 - 0.15 12.5 0.1 16 6.1 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain DDE_1 PF03184.19 OAJ20486.1 - 8.2e-21 74.4 0.0 1.8e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ20486.1 - 1.2e-08 34.8 0.0 5.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAJ20486.1 - 0.00014 21.6 0.1 0.0031 17.3 0.1 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4776 PF16003.5 OAJ20486.1 - 1.7 7.6 6.6 0.16 10.9 0.9 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4776) RPN1_RPN2_N PF17781.1 OAJ20488.1 - 2.2e-114 382.0 0.0 5.8e-114 380.6 0.0 1.8 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAJ20488.1 - 2.8e-28 97.7 0.4 8.2e-28 96.2 0.0 2.0 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAJ20488.1 - 1.3e-15 56.9 18.3 0.0011 19.3 0.0 8.3 8 0 0 8 8 8 5 Proteasome/cyclosome repeat T2SSF PF00482.23 OAJ20488.1 - 0.12 12.3 0.9 15 5.5 0.0 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FYDLN_acid PF09538.10 OAJ20488.1 - 1.9 9.2 17.8 1.8 9.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HEAT_2 PF13646.6 OAJ20488.1 - 8.6 6.8 13.6 1.5 9.3 0.1 4.9 5 1 0 5 5 5 0 HEAT repeats Sel1 PF08238.12 OAJ20489.1 - 3.7e-36 122.7 22.3 1.8e-06 28.4 0.4 8.5 8 0 0 8 8 8 7 Sel1 repeat HLH PF00010.26 OAJ20489.1 - 1.8e-14 53.4 3.8 9.3e-09 35.1 0.0 3.0 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain TSC22 PF01166.18 OAJ20490.1 - 0.0061 16.8 0.4 0.0061 16.8 0.4 2.1 2 0 0 2 2 2 1 TSC-22/dip/bun family HOOK PF05622.12 OAJ20490.1 - 0.037 12.2 5.8 0.055 11.6 5.8 1.2 1 0 0 1 1 1 0 HOOK protein GAS PF13851.6 OAJ20490.1 - 0.072 12.4 6.2 3 7.1 0.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 OAJ20490.1 - 0.2 11.7 10.5 2.3 8.2 1.3 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 OAJ20490.1 - 0.24 12.1 4.1 1.8 9.3 0.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA HAP1_N PF04849.13 OAJ20490.1 - 0.63 9.2 9.3 1.9 7.6 0.4 2.4 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF4472 PF14739.6 OAJ20490.1 - 1.6 9.5 8.1 9.5 7.0 1.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 OAJ20490.1 - 2.6 8.6 9.5 6.8 7.2 4.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_60s PF00428.19 OAJ20491.1 - 7.8e-20 71.3 9.5 7.8e-20 71.3 9.5 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sulf_transp PF04143.14 OAJ20491.1 - 0.00024 20.8 3.9 0.00024 20.8 3.9 2.9 1 1 1 2 2 2 1 Sulphur transport CD20 PF04103.15 OAJ20491.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 CD20-like family DUF1631 PF07793.11 OAJ20491.1 - 0.023 13.1 1.1 0.035 12.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Cyclase PF04199.13 OAJ20532.1 - 4.5e-12 46.4 0.0 9.4e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase SAE2 PF08573.10 OAJ20533.1 - 2.7e-12 47.8 2.9 2.7e-12 47.8 2.9 3.7 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DctP PF03480.13 OAJ20533.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Mvb12 PF09452.10 OAJ20533.1 - 0.19 12.2 2.8 0.18 12.3 0.5 2.2 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 CPSase_L_D2 PF02786.17 OAJ20534.1 - 5.5e-83 277.6 0.1 9.6e-83 276.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAJ20534.1 - 9.4e-70 234.4 0.0 1.8e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAJ20534.1 - 1.1e-39 135.4 0.1 2.8e-39 134.1 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ20534.1 - 3.4e-31 107.5 0.0 8.3e-31 106.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAJ20534.1 - 3.9e-28 98.7 0.0 8.5e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAJ20534.1 - 1.2e-13 50.7 0.7 2.4e-13 49.7 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ20534.1 - 6.5e-11 41.9 0.5 7e-05 22.6 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 OAJ20534.1 - 3.6e-10 39.7 0.0 6.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAJ20534.1 - 4e-07 29.8 0.0 9.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAJ20534.1 - 3.5e-05 23.9 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAJ20534.1 - 4.3e-05 24.2 0.2 0.5 11.1 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 OAJ20534.1 - 9.1e-05 21.8 0.0 0.026 13.8 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 OAJ20534.1 - 0.00075 19.1 0.0 0.0024 17.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 OAJ20534.1 - 0.0027 17.3 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAJ20534.1 - 0.0049 16.6 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Sacchrp_dh_NADP PF03435.18 OAJ20534.1 - 0.074 13.3 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Acyl-CoA_dh_1 PF00441.24 OAJ20535.1 - 3e-28 98.9 2.4 4.7e-28 98.3 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ20535.1 - 2.9e-18 65.8 0.0 9.6e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ20535.1 - 1.5e-12 48.0 4.8 1.5e-12 48.0 4.8 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ20535.1 - 1.9e-10 41.4 0.0 3.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain RVT_1 PF00078.27 OAJ20537.1 - 1.2e-23 83.8 0.0 2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ20537.1 - 1e-14 54.3 0.0 1.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ20537.1 - 1.8e-14 53.6 0.0 5.4e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ20537.1 - 1.1e-09 38.4 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ20537.1 - 0.0034 17.6 0.0 0.0079 16.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ20537.1 - 0.0092 16.6 0.5 0.036 14.7 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ20537.1 - 0.12 13.0 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Patatin PF01734.22 OAJ20539.1 - 0.029 14.5 1.1 0.05 13.8 1.1 1.4 1 1 0 1 1 1 0 Patatin-like phospholipase CDC45 PF02724.14 OAJ20539.1 - 0.97 7.6 3.4 1.3 7.2 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TT_ORF2 PF02957.15 OAJ20539.1 - 2 9.3 11.1 3.6 8.5 0.7 2.3 2 0 0 2 2 2 0 TT viral ORF2 Apt1 PF10351.9 OAJ20539.1 - 2.3 6.9 3.7 2.8 6.7 3.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mlf1IP PF10248.9 OAJ20540.1 - 0.079 12.9 2.8 0.19 11.7 2.8 1.6 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein PBP1_TM PF14812.6 OAJ20541.1 - 0.012 15.9 7.5 0.2 12.0 2.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Plavaka PF18759.1 OAJ20541.1 - 0.047 12.9 0.1 0.12 11.6 0.1 1.6 1 1 0 1 1 1 0 Plavaka transposase DUF3827 PF12877.7 OAJ20541.1 - 0.15 10.4 4.9 0.25 9.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Histone PF00125.24 OAJ20542.1 - 1.2e-36 126.0 0.2 1.4e-36 125.7 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ20542.1 - 9.6e-06 25.7 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ20542.1 - 0.00068 20.0 0.0 0.00096 19.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAJ20542.1 - 0.087 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ20542.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OAJ20543.1 - 4.8e-37 127.2 0.2 5.3e-37 127.1 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ20543.1 - 1.2e-05 25.3 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ20543.1 - 0.00079 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAJ20543.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ20543.1 - 0.13 12.4 0.1 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Zn_clus PF00172.18 OAJ20581.1 - 2.3e-06 27.6 9.1 4.1e-06 26.8 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAJ20581.1 - 0.77 9.3 10.9 2 8.0 10.9 1.6 1 0 0 1 1 1 0 Spt20 family LIM_bind PF01803.16 OAJ20581.1 - 1.7 8.1 6.0 0.4 10.2 2.1 1.8 2 0 0 2 2 2 0 LIM-domain binding protein Transposase_21 PF02992.14 OAJ20583.1 - 1.7e-10 40.5 0.0 3.6e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ20583.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) ETF_QO PF05187.13 OAJ20584.1 - 2.9e-41 139.8 0.2 4.8e-41 139.1 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 OAJ20584.1 - 8.2e-08 31.7 0.2 5.7e-05 22.4 0.3 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ20584.1 - 1.5e-06 28.1 1.3 0.0016 18.1 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ20584.1 - 1.7e-06 28.2 0.0 5.6e-06 26.5 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ20584.1 - 1.6e-05 24.3 0.0 0.00045 19.5 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAJ20584.1 - 7.4e-05 21.6 0.2 0.00012 20.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ20584.1 - 9.6e-05 21.8 0.4 0.00016 21.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ20584.1 - 0.00014 21.2 0.1 0.00033 20.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ20584.1 - 0.00035 19.7 0.0 0.00062 18.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 OAJ20584.1 - 0.0042 17.6 1.1 0.01 16.4 1.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.7 OAJ20584.1 - 0.0051 16.2 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ20584.1 - 0.0074 16.8 0.2 0.63 10.6 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ20584.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAJ20584.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_21 PF14697.6 OAJ20584.1 - 0.031 14.4 0.3 0.069 13.3 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 OAJ20584.1 - 0.082 13.0 0.4 0.082 13.0 0.4 1.7 2 0 0 2 2 1 0 4Fe-4S binding domain FAD_binding_3 PF01494.19 OAJ20584.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Fer4_6 PF12837.7 OAJ20584.1 - 1.7 8.8 4.2 0.83 9.8 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain CDC50 PF03381.15 OAJ20586.1 - 5.6e-87 291.8 0.0 6.8e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF382 PF04037.13 OAJ20589.1 - 2.1e-53 179.8 0.0 4e-53 178.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 OAJ20589.1 - 1.1e-18 66.8 4.6 2.3e-18 65.8 4.6 1.6 1 0 0 1 1 1 1 PSP PBP1_TM PF14812.6 OAJ20589.1 - 3.4 8.1 23.0 1.2 9.6 0.6 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Elongin_A PF06881.11 OAJ20590.1 - 1e-25 90.2 0.2 1.5e-25 89.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Thioredoxin_4 PF13462.6 OAJ20591.1 - 1.7e-06 28.3 0.0 1.4e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin tRNA_synthFbeta PF17759.1 OAJ20592.1 - 3e-44 151.0 0.0 6.1e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAJ20592.1 - 2.3e-29 101.4 0.1 9.2e-28 96.3 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAJ20592.1 - 1.4e-27 96.5 0.0 3e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAJ20592.1 - 5.1e-20 71.6 0.0 4.2e-18 65.4 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain Slu7 PF11708.8 OAJ20593.1 - 1.2e-103 346.5 20.4 1.2e-103 346.5 20.4 2.9 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Beta_elim_lyase PF01212.21 OAJ20594.1 - 5.5e-61 206.4 0.0 7e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAJ20594.1 - 1.1e-05 24.8 0.0 0.00069 18.9 0.0 2.2 3 0 0 3 3 3 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAJ20594.1 - 0.00036 20.0 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family bZIP_1 PF00170.21 OAJ20595.1 - 3.3e-08 33.5 6.8 3.5e-06 27.0 3.7 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OAJ20595.1 - 7.5e-06 25.9 5.5 7.5e-06 25.9 5.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper RAC_head PF16717.5 OAJ20595.1 - 0.0029 18.6 2.1 0.0055 17.7 2.1 1.4 1 0 0 1 1 1 1 Ribosome-associated complex head domain DUF3450 PF11932.8 OAJ20595.1 - 0.024 13.9 2.0 0.038 13.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PGBA_C PF15437.6 OAJ20595.1 - 0.12 12.8 1.6 0.25 11.8 1.6 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Glutaredoxin2_C PF04399.13 OAJ20595.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain YabA PF06156.13 OAJ20595.1 - 0.55 10.9 1.8 2.3 8.9 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PKcGMP_CC PF16808.5 OAJ20595.1 - 0.74 9.7 3.1 0.54 10.2 0.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_S20p PF01649.18 OAJ20595.1 - 2.4 8.8 5.3 2.6 8.7 3.1 2.1 2 1 0 2 2 2 0 Ribosomal protein S20 Ribosomal_L28e PF01778.17 OAJ20631.1 - 6.7e-35 120.3 1.7 8.4e-35 120.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 OAJ20631.1 - 4.5e-23 81.7 30.3 4.5e-23 81.7 30.3 3.3 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAJ20631.1 - 1.2e-06 28.2 25.5 1.6e-06 27.8 25.5 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 OAJ20631.1 - 0.0076 16.0 2.3 0.013 15.3 2.3 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain TFIIA PF03153.13 OAJ20631.1 - 0.14 12.2 17.8 0.2 11.6 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OAJ20631.1 - 0.83 7.8 38.4 1.1 7.4 38.4 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 OAJ20631.1 - 1 8.0 12.3 1.4 7.6 12.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GST_N PF02798.20 OAJ20632.1 - 6e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ20632.1 - 4e-13 49.6 0.0 5.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ20632.1 - 2.2e-09 37.5 0.0 3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OAJ20632.1 - 0.0024 18.6 0.0 0.0038 17.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OAJ20632.1 - 0.026 14.8 0.0 0.035 14.4 0.0 1.3 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein RRM_1 PF00076.22 OAJ20633.1 - 1.8e-26 91.7 0.1 2.9e-12 46.2 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ20633.1 - 0.00045 20.3 0.0 0.0047 17.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 OAJ20633.1 - 0.0098 15.7 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RhoGAP PF00620.27 OAJ20634.1 - 2.1e-37 128.3 0.1 4.6e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 OAJ20634.1 - 3.9e-23 81.4 33.8 7.6e-10 38.9 6.3 5.1 5 0 0 5 5 5 4 LIM domain Gar1 PF04410.14 OAJ20635.1 - 2.5e-35 121.5 0.0 3.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region P5CR_dimer PF14748.6 OAJ20636.1 - 7e-38 129.0 3.4 1.9e-37 127.6 3.4 1.8 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAJ20636.1 - 7.2e-14 52.2 0.0 3.8e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent TrmK PF04816.12 OAJ20636.1 - 0.08 12.5 0.0 2.4 7.6 0.1 2.2 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Collagen PF01391.18 OAJ20637.1 - 5.8e-08 32.4 19.0 9.3e-08 31.7 19.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) AA_permease PF00324.21 OAJ20638.1 - 4.4e-65 220.1 31.6 5.8e-65 219.7 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAJ20638.1 - 5.5e-18 65.2 6.3 4.2e-09 35.9 0.0 4.3 4 0 0 4 4 4 3 Solute carrier family 12 WD40 PF00400.32 OAJ20639.1 - 4.2e-22 78.0 11.7 1.1e-09 38.8 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ20639.1 - 1.3e-07 31.8 0.3 0.067 13.5 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ20639.1 - 0.0042 16.1 0.0 0.063 12.2 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ20639.1 - 0.16 10.6 0.1 9.4 4.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 FAM60A PF15396.6 OAJ20640.1 - 7.1 6.6 9.5 1.7 8.6 5.7 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Ssl1 PF04056.14 OAJ20641.1 - 3.3e-69 232.5 0.0 7.1e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 OAJ20641.1 - 3.2e-15 56.1 4.7 3.2e-15 56.1 4.7 3.3 2 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 OAJ20641.1 - 5.7e-12 46.2 0.0 1.4e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 OAJ20641.1 - 0.00029 21.5 4.6 0.0078 16.9 1.9 3.0 2 1 0 2 2 2 1 zinc-ribbon family IBR PF01485.21 OAJ20641.1 - 0.0024 18.0 0.7 0.0024 18.0 0.7 3.0 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain VWA PF00092.28 OAJ20641.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-C4H2 PF10146.9 OAJ20641.1 - 0.072 13.4 3.4 17 5.6 0.0 2.6 2 1 0 2 2 2 0 Zinc finger-containing protein Tfb4 PF03850.14 OAJ20641.1 - 0.57 9.6 6.7 4 6.9 6.2 2.4 2 1 1 3 3 3 0 Transcription factor Tfb4 DZR PF12773.7 OAJ20641.1 - 1.8 8.6 23.6 1.1 9.3 8.1 3.2 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 OAJ20641.1 - 2.8 8.0 11.2 40 4.3 2.1 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Dynein_light PF01221.18 OAJ20642.1 - 6.7e-35 119.3 0.1 7.9e-35 119.0 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4726 PF15855.5 OAJ20642.1 - 0.0029 17.8 0.6 0.0041 17.3 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4726) Pkinase PF00069.25 OAJ20643.1 - 4.4e-72 242.6 0.0 5.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20643.1 - 1.1e-45 155.9 0.0 1.7e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAJ20643.1 - 1.4e-22 79.8 0.1 3e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OAJ20643.1 - 6.6e-06 25.1 0.0 9.9e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ20643.1 - 0.00025 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 OAJ20643.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 OAJ20643.1 - 0.033 14.1 0.6 0.73 9.7 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ20643.1 - 0.17 11.2 1.7 1.7 7.9 0.3 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ20643.1 - 0.36 9.7 1.0 0.93 8.4 1.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain ORC5_C PF14630.6 OAJ20675.1 - 3.2e-49 168.0 0.2 8e-49 166.7 0.2 1.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAJ20675.1 - 0.00056 20.3 2.8 0.00096 19.6 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain zf-HIT PF04438.16 OAJ20676.1 - 1.9e-08 34.0 9.2 3.1e-08 33.3 9.2 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF5516 PF17637.2 OAJ20678.1 - 0.037 13.8 0.2 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5516) Beta_protein PF14350.6 OAJ20678.1 - 0.053 12.9 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 Beta protein DUF2012 PF09430.10 OAJ20679.1 - 5.1e-21 75.0 0.0 1.3e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) Cnd1 PF12717.7 OAJ20680.1 - 1.5e-54 184.4 2.3 1.2e-47 161.9 0.1 3.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 OAJ20680.1 - 4.9e-37 127.3 0.0 4.9e-37 127.3 0.0 4.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 OAJ20680.1 - 1.5e-08 33.7 1.9 0.013 14.1 0.1 4.6 4 2 1 5 5 5 4 Adaptin N terminal region HEAT PF02985.22 OAJ20680.1 - 1.1e-06 28.4 0.7 0.82 10.1 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OAJ20680.1 - 4.1e-06 27.1 1.3 0.45 10.9 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats Cnd3 PF12719.7 OAJ20680.1 - 8.9e-06 25.1 1.0 0.00021 20.6 0.3 2.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OAJ20680.1 - 0.00017 21.8 0.5 0.44 10.7 0.1 3.8 2 2 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAJ20680.1 - 0.068 13.7 6.2 1.9 9.1 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat XAP5 PF04921.14 OAJ20680.1 - 6.2 6.6 11.0 18 5.0 11.0 1.7 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.14 OAJ20680.1 - 7.2 4.8 23.3 0.023 13.0 13.7 1.5 2 0 0 2 2 2 0 CDC45-like protein Fungal_trans PF04082.18 OAJ20681.1 - 6.1e-06 25.5 0.0 1.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ20681.1 - 0.0027 17.8 5.9 0.27 11.4 0.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CcdA PF07362.12 OAJ20681.1 - 0.24 11.9 0.5 0.6 10.6 0.5 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA DSPc PF00782.20 OAJ20682.1 - 3.5e-06 26.9 0.0 7.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ20682.1 - 8.7e-05 22.2 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.12 OAJ20682.1 - 0.047 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 OAJ20682.1 - 0.094 12.8 0.2 0.4 10.8 0.0 2.1 3 0 0 3 3 3 0 Inositol hexakisphosphate CX9C PF16860.5 OAJ20683.1 - 4.5e-14 52.2 1.3 5.3e-10 39.1 0.7 2.5 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 OAJ20683.1 - 0.0013 19.0 2.8 0.065 13.6 0.3 2.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 OAJ20683.1 - 0.022 15.2 0.6 1.7 9.1 0.2 2.2 1 1 1 2 2 2 0 GCK domain Cmc1 PF08583.10 OAJ20683.1 - 0.03 14.3 6.2 1.7 8.7 1.2 3.4 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like YbfN PF13982.6 OAJ20683.1 - 0.034 14.4 0.3 11 6.4 0.0 2.3 2 0 0 2 2 2 0 YbfN-like lipoprotein CHCH PF06747.13 OAJ20683.1 - 0.25 11.5 3.7 13 6.0 0.2 3.3 3 1 0 3 3 3 0 CHCH domain NDUF_B7 PF05676.13 OAJ20683.1 - 0.62 9.8 8.9 5.9 6.7 1.2 3.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 OAJ20683.1 - 3 8.1 6.7 32 4.9 0.2 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0203) Zn_clus PF00172.18 OAJ20684.1 - 2e-06 27.8 4.8 1.2e-05 25.3 4.8 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyr-DNA_phospho PF06087.12 OAJ20685.1 - 6.3e-38 130.8 0.0 4.1e-26 91.9 0.0 2.7 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase DCP2 PF05026.13 OAJ20686.1 - 6.1e-24 84.2 0.1 1.1e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OAJ20686.1 - 2.2e-15 56.8 0.0 4.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SH3_1 PF00018.28 OAJ20737.1 - 9.5e-25 86.0 0.0 2e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAJ20737.1 - 2.4e-14 52.9 0.0 2.6e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 OAJ20737.1 - 1.2e-13 50.5 0.0 9.3e-09 34.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 OAJ20737.1 - 1.3e-10 41.2 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 OAJ20737.1 - 7.4e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rxt3 PF08642.10 OAJ20738.1 - 1.9e-16 61.0 0.0 1.9e-16 61.0 0.0 7.7 4 3 1 5 5 5 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAJ20738.1 - 0.023 14.8 0.0 0.078 13.1 0.0 1.8 1 0 0 1 1 1 0 LCCL domain zf-BED PF02892.15 OAJ20740.1 - 0.072 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 BED zinc finger MULE PF10551.9 OAJ20742.1 - 8.5e-11 42.1 1.0 1.2e-06 28.9 0.1 3.0 2 1 1 3 3 3 2 MULE transposase domain Peptidase_C48 PF02902.19 OAJ20742.1 - 2.7e-09 37.2 0.1 7.2e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain BSP_II PF05432.11 OAJ20742.1 - 3 7.5 9.4 1.4 8.5 0.9 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) bVLRF1 PF18826.1 OAJ20743.1 - 1.9e-41 141.4 0.0 3.5e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_3 PF13606.6 OAJ20743.1 - 0.17 12.5 0.0 0.7 10.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat TT_ORF2 PF02957.15 OAJ20743.1 - 0.84 10.6 7.3 4 8.4 7.3 2.2 1 0 0 1 1 1 0 TT viral ORF2 E3_binding PF02817.17 OAJ20744.1 - 2.4e-07 31.0 0.0 7.4e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Response_reg PF00072.24 OAJ20745.1 - 4.9e-09 36.3 0.0 5.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain CBFD_NFYB_HMF PF00808.23 OAJ20746.1 - 5.7e-13 48.9 0.5 1.1e-12 48.1 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1180 PF06679.12 OAJ20746.1 - 0.0032 17.9 2.0 0.0032 17.9 2.0 2.2 2 0 0 2 2 1 1 Protein of unknown function (DUF1180) TFIIA PF03153.13 OAJ20746.1 - 0.05 13.6 10.7 0.069 13.1 10.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ20746.1 - 0.14 11.8 11.7 0.2 11.3 11.7 1.3 1 0 0 1 1 1 0 Spt20 family KAR9 PF08580.10 OAJ20746.1 - 0.44 9.0 4.3 0.54 8.7 4.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPX PF03105.19 OAJ20746.1 - 1.3 8.9 11.4 1.9 8.3 11.4 1.2 1 1 0 1 1 1 0 SPX domain SOG2 PF10428.9 OAJ20746.1 - 2.3 7.3 7.1 3 7.0 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SAGA-Tad1 PF12767.7 OAJ20746.1 - 2.6 7.7 6.1 11 5.7 6.1 1.9 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CNDH2_M PF16869.5 OAJ20746.1 - 3 8.5 16.5 1.8 9.3 3.6 2.5 2 0 0 2 2 2 0 PF16858 Ndc1_Nup PF09531.10 OAJ20746.1 - 3.3 6.3 5.7 3.8 6.1 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Histone PF00125.24 OAJ20746.1 - 4.3 7.7 16.3 39 4.6 14.4 2.7 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Ku PF02735.16 OAJ20747.1 - 5e-32 111.3 0.0 2.8e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAJ20747.1 - 7.2e-14 52.1 0.0 1.7e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 OAJ20747.1 - 1.1e-07 31.4 0.4 2.6e-07 30.2 0.2 1.7 2 0 0 2 2 2 1 SAP domain Ku_C PF03730.14 OAJ20747.1 - 0.0029 18.2 6.0 0.0034 18.0 0.1 3.3 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm Nop53 PF07767.11 OAJ20747.1 - 0.0074 15.7 2.3 0.015 14.7 2.3 1.4 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PDE6_gamma PF04868.12 OAJ20747.1 - 0.043 14.0 0.2 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Spt5_N PF11942.8 OAJ20747.1 - 0.046 14.7 8.7 0.059 14.4 6.8 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BNIP2 PF12496.8 OAJ20747.1 - 0.2 12.1 4.3 0.2 12.1 2.7 1.8 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Cwf_Cwc_15 PF04889.12 OAJ20747.1 - 0.25 11.0 6.1 0.44 10.2 6.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med4 PF10018.9 OAJ20749.1 - 2.3e-15 56.8 3.2 3.4e-15 56.3 3.2 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 zf-C2HC5 PF06221.13 OAJ20750.1 - 7.9e-08 32.2 7.3 1.5e-07 31.3 7.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TT_ORF2 PF02957.15 OAJ20750.1 - 0.53 11.2 14.0 2 9.3 2.7 3.6 3 0 0 3 3 3 0 TT viral ORF2 Mito_carr PF00153.27 OAJ20751.1 - 1.4e-62 207.6 6.6 2.3e-20 72.3 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein HAD_2 PF13419.6 OAJ20789.1 - 5.1e-11 43.0 0.0 3.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ20789.1 - 9.5e-09 35.8 0.0 1.5e-07 32.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ20789.1 - 2.2e-06 27.6 0.0 4.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 OAJ20789.1 - 0.072 12.7 0.0 1.5 8.4 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial PGP phosphatase 5_nucleotid PF05761.14 OAJ20789.1 - 0.22 10.4 0.0 7.2 5.4 0.0 2.1 2 0 0 2 2 2 0 5' nucleotidase family PTP_tm PF18861.1 OAJ20790.1 - 0.044 13.8 0.7 0.072 13.1 0.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 OAJ20790.1 - 0.2 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless RNA_pol_Rpb1_1 PF04997.12 OAJ20792.1 - 1.8e-87 293.6 0.1 2.9e-87 292.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OAJ20792.1 - 4.6e-82 275.4 0.2 7.4e-82 274.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAJ20792.1 - 4.7e-69 231.8 0.0 8.4e-69 231.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ20792.1 - 7.7e-38 129.9 0.0 1.7e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAJ20792.1 - 2.2e-27 95.1 0.0 5.3e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 adh_short PF00106.25 OAJ20793.1 - 5.2e-26 91.3 0.0 2e-24 86.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ20793.1 - 6.4e-14 52.1 0.1 1.5e-12 47.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ20793.1 - 3.7e-08 33.5 0.8 1.2e-07 31.8 0.8 1.8 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAJ20793.1 - 0.0016 17.8 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 OAJ20793.1 - 0.023 14.6 0.1 0.68 9.8 0.1 2.4 1 1 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 OAJ20793.1 - 0.035 14.7 0.2 0.075 13.6 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAJ20793.1 - 0.036 14.0 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 OAJ20793.1 - 0.084 12.8 0.1 0.25 11.2 0.2 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus AICARFT_IMPCHas PF01808.18 OAJ20794.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Pex24p PF06398.11 OAJ20795.1 - 9.2e-34 117.0 0.4 3.1e-27 95.5 0.0 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Polysacc_deac_1 PF01522.21 OAJ20796.1 - 5.2e-23 81.3 0.0 9.5e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 OAJ20796.1 - 0.0033 16.9 0.0 0.007 15.9 0.0 1.7 1 0 0 1 1 1 1 Virulence protein nec1 HTH_Tnp_ISL3 PF13542.6 OAJ20797.1 - 0.0081 15.5 2.1 0.031 13.7 2.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 SufE PF02657.15 OAJ20797.1 - 0.093 12.6 1.1 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 Fe-S metabolism associated domain FAM176 PF14851.6 OAJ20797.1 - 4.1 7.1 12.9 3.9 7.1 2.1 3.1 2 0 0 2 2 2 0 FAM176 family Arm PF00514.23 OAJ20797.1 - 6.4 7.0 9.9 5.6 7.1 0.4 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.25 OAJ20798.1 - 1.7e-12 47.4 0.0 4.4e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) NOA36 PF06524.12 OAJ20798.1 - 1.2 8.3 13.1 3.2 7.0 13.1 1.6 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OAJ20798.1 - 1.3 7.2 17.2 2.5 6.2 17.2 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ20798.1 - 2.3 6.2 14.3 4 5.4 14.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pro_isomerase PF00160.21 OAJ20799.1 - 1.3e-51 175.0 0.0 1.5e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA_21 PF13304.6 OAJ20800.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1168 PF06658.12 OAJ20800.1 - 0.81 9.5 7.9 2.1 8.2 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pox_Ag35 PF03286.14 OAJ20800.1 - 2 8.2 8.8 0.9 9.3 3.6 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Aminotran_1_2 PF00155.21 OAJ20801.1 - 1.5e-54 185.6 0.0 2.6e-54 184.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ20801.1 - 0.021 14.1 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase zn-ribbon_14 PF16503.5 OAJ20836.1 - 1.5e-17 62.8 2.7 1.5e-17 62.8 2.7 3.1 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 OAJ20836.1 - 2e-15 57.0 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 OAJ20836.1 - 0.0079 15.7 1.7 0.0079 15.7 1.7 3.0 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 OAJ20836.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DZR PF12773.7 OAJ20836.1 - 0.77 9.8 9.0 6.1 7.0 0.1 3.3 3 0 0 3 3 3 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OAJ20836.1 - 2 8.0 10.4 0.68 9.5 0.5 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding NuA4 PF09340.10 OAJ20837.1 - 2e-20 72.5 0.0 3.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Cyt-b5 PF00173.28 OAJ20838.1 - 3.9e-18 65.4 0.0 5.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3530 PF12048.8 OAJ20838.1 - 0.95 8.8 5.4 1.1 8.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DAD PF02109.16 OAJ20839.1 - 2.1e-46 156.7 2.7 3e-46 156.2 2.7 1.2 1 0 0 1 1 1 1 DAD family Pex14_N PF04695.13 OAJ20839.1 - 0.0099 16.5 8.3 0.017 15.8 8.3 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MDFI PF15316.6 OAJ20839.1 - 0.026 14.6 0.5 0.037 14.1 0.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Med13_C PF06333.12 OAJ20839.1 - 0.031 13.5 3.8 0.029 13.7 3.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rotamase_2 PF13145.6 OAJ20839.1 - 0.54 11.1 5.8 0.21 12.5 3.5 1.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain MAGE_N PF12440.8 OAJ20839.1 - 3 8.6 20.3 5.4 7.8 20.3 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Calpain_inhib PF00748.19 OAJ20839.1 - 5.7 7.5 12.7 10 6.6 12.7 1.5 1 0 0 1 1 1 0 Calpain inhibitor Alpha_GJ PF03229.13 OAJ20839.1 - 9.7 6.8 13.8 11 6.6 10.1 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Bac_surface_Ag PF01103.23 OAJ20840.1 - 3.7e-25 89.1 0.4 7.6e-25 88.1 0.4 1.4 1 1 0 1 1 1 1 Surface antigen DUF3381 PF11861.8 OAJ20842.1 - 0.0053 16.6 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Paf1 PF03985.13 OAJ20845.1 - 4e-43 148.0 33.4 1.8e-22 80.0 0.0 4.9 4 1 1 5 5 5 3 Paf1 Pex24p PF06398.11 OAJ20846.1 - 0.00014 21.0 2.0 0.00026 20.1 2.0 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin ATP-synt_B PF00430.18 OAJ20846.1 - 5.1 7.2 12.4 7.3 6.7 12.4 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Retrotrans_gag PF03732.17 OAJ20847.1 - 3.4e-07 30.5 0.1 9.4e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 OAJ20847.1 - 1e-06 28.5 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 OAJ20847.1 - 0.1 12.3 1.9 0.2 11.4 1.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger rve PF00665.26 OAJ20848.1 - 8.3e-23 80.8 0.1 1.7e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ20848.1 - 1.1e-06 28.4 0.0 7.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ20848.1 - 0.0016 18.2 0.1 0.0075 16.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain TcpQ PF10671.9 OAJ20848.1 - 0.054 13.6 1.3 3.7 7.7 0.3 2.5 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q PRCC PF10253.9 OAJ20849.1 - 1.6e-12 48.7 12.5 2.7e-12 48.0 12.5 1.4 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Macoilin PF09726.9 OAJ20849.1 - 6.2 5.2 9.2 4.9 5.6 7.2 1.8 2 0 0 2 2 2 0 Macoilin family Het-C PF07217.11 OAJ20850.1 - 8.6e-211 701.3 0.0 2.3e-210 699.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF502 PF04367.13 OAJ20850.1 - 0.014 15.3 0.1 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DUF2780 PF11075.8 OAJ20850.1 - 0.036 14.2 0.5 0.87 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) NAD_binding_1 PF00175.21 OAJ20852.1 - 1.3e-25 90.2 0.0 2.9e-25 89.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAJ20852.1 - 3e-20 72.4 0.0 7e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAJ20852.1 - 4e-07 30.3 0.0 2.4e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAJ20852.1 - 0.0068 16.6 0.0 0.041 14.1 0.0 2.3 3 0 0 3 3 3 1 Siderophore-interacting FAD-binding domain DUF5336 PF17270.2 OAJ20852.1 - 0.0076 15.9 1.1 0.012 15.3 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5336) ATP19 PF11022.8 OAJ20853.1 - 7.7e-20 71.0 0.2 9.4e-20 70.8 0.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit K HA2 PF04408.23 OAJ20854.1 - 8.9e-24 83.9 2.1 9.6e-24 83.8 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ20854.1 - 6.3e-21 74.5 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ20854.1 - 6.3e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 OAJ20854.1 - 0.00018 20.6 0.0 0.00046 19.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 OAJ20854.1 - 0.00025 21.3 0.1 0.00062 20.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAJ20854.1 - 0.00027 20.7 0.8 0.00056 19.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ20854.1 - 0.00071 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ20854.1 - 0.02 15.2 0.1 0.02 15.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAJ20854.1 - 0.051 14.1 0.3 0.52 10.8 0.3 2.4 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OAJ20854.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ20854.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein YqcI_YcgG PF08892.11 OAJ20855.1 - 0.049 13.4 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 YqcI/YcgG family FAM176 PF14851.6 OAJ20897.1 - 0.068 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 OAJ20897.1 - 0.12 12.8 7.1 0.19 12.1 7.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFB6 PF17110.5 OAJ20897.1 - 0.24 11.1 1.7 0.39 10.4 1.7 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PBP1_TM PF14812.6 OAJ20897.1 - 0.67 10.4 9.0 1.2 9.6 9.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 OAJ20897.1 - 1.2 8.2 11.8 1.7 7.7 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OAJ20897.1 - 3.3 5.7 6.6 3.6 5.6 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ20897.1 - 4.3 6.6 11.3 5.9 6.1 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 OAJ20899.1 - 7.7e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAJ20899.1 - 1.2e-07 32.2 3.6 1.2e-07 32.2 3.6 2.9 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 SDH_alpha PF03313.15 OAJ20900.1 - 3.9e-100 334.8 1.5 5.2e-100 334.4 1.5 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 OAJ20900.1 - 1.7e-55 187.7 0.1 6.7e-55 185.7 0.0 2.0 3 0 0 3 3 3 1 Serine dehydratase beta chain Suf PF05843.14 OAJ20901.1 - 1.7e-82 277.7 0.3 8.1e-79 265.7 0.0 4.2 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAJ20901.1 - 1.9e-06 28.2 8.0 7.4 7.7 0.0 8.4 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ20901.1 - 2.2e-05 24.9 0.0 0.54 10.8 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_23 PF13489.6 OAJ20902.1 - 1e-09 38.4 0.0 2.5e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ20902.1 - 4.8e-08 33.6 0.0 1.3e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ20902.1 - 5e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ20902.1 - 0.0033 18.1 0.0 0.0066 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ20902.1 - 0.0056 16.2 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Sacchrp_dh_NADP PF03435.18 OAJ20902.1 - 0.13 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-C2H2 PF00096.26 OAJ20903.1 - 6.3e-10 39.0 7.7 0.00019 21.7 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ20903.1 - 4e-06 27.0 0.7 4e-06 27.0 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ20903.1 - 7.6e-06 26.3 7.4 0.001 19.7 0.5 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ20903.1 - 1.3e-05 25.3 3.4 0.1 12.9 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAJ20903.1 - 0.16 12.5 6.2 0.14 12.7 0.7 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger AKAP95 PF04988.12 OAJ20904.1 - 0.072 13.3 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) CDC37_N PF03234.14 OAJ20904.1 - 1.9 9.4 5.5 1.3 9.9 3.1 1.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Peptidase_A22B PF04258.13 OAJ20905.1 - 1.2e-77 261.3 4.9 1.7e-77 260.7 4.9 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OAJ20905.1 - 4e-07 29.8 3.8 7.6e-07 28.9 3.8 1.5 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease CENP-B_dimeris PF09026.10 OAJ20905.1 - 0.00091 19.6 0.3 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.6 OAJ20905.1 - 0.015 15.0 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 FAM176 family zf-C2HE PF16278.5 OAJ20906.1 - 0.00047 20.5 0.0 0.0011 19.4 0.0 1.6 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 OAJ20906.1 - 0.00051 20.5 0.6 0.00092 19.7 0.6 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Abhydrolase_1 PF00561.20 OAJ20907.1 - 1.7e-15 57.4 0.1 9.3e-12 45.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ20907.1 - 6e-14 52.0 0.0 1.8e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein DcpS_C PF11969.8 OAJ20908.1 - 1.7e-10 41.4 0.5 0.00056 20.4 0.2 2.4 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ20908.1 - 1.6e-06 28.8 0.5 0.062 14.1 0.0 2.4 2 0 0 2 2 2 2 HIT domain zf-C2HE PF16278.5 OAJ20908.1 - 0.00031 21.1 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Pkinase PF00069.25 OAJ20909.1 - 6.5e-66 222.4 0.0 9.1e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20909.1 - 4.4e-42 144.2 0.0 6.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 OAJ20909.1 - 6.6e-12 45.7 0.1 2.8e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAJ20909.1 - 2e-11 43.8 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 OAJ20909.1 - 4.1e-11 43.1 0.0 9.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 OAJ20909.1 - 1.6e-07 30.9 0.0 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Mpp10 PF04006.12 OAJ20909.1 - 0.05 12.0 1.7 0.082 11.4 1.7 1.2 1 0 0 1 1 1 0 Mpp10 protein SAM_4 PF18017.1 OAJ20909.1 - 0.062 13.3 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RA PF00788.23 OAJ20909.1 - 0.18 12.5 0.0 0.64 10.7 0.0 2.0 1 1 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PPP4R2 PF09184.11 OAJ20909.1 - 0.75 9.3 5.6 1.9 8.0 5.6 1.7 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAJ20909.1 - 3.7 6.8 8.8 6.6 6.0 8.8 1.3 1 0 0 1 1 1 0 NOA36 protein Cep57_MT_bd PF06657.13 OAJ20910.1 - 1.3e-08 35.1 1.8 1.3e-08 35.1 1.8 3.4 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Vpu PF00558.19 OAJ20910.1 - 0.23 11.2 3.9 18 5.2 3.0 2.8 2 0 0 2 2 2 0 Vpu protein CTU2 PF10288.9 OAJ20910.1 - 0.36 11.1 1.4 2.6 8.3 1.4 2.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 F-box-like PF12937.7 OAJ20946.1 - 0.0016 18.3 0.1 0.0048 16.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like PikAIV_N PF18605.1 OAJ20947.1 - 0.065 12.8 3.3 0.16 11.6 3.3 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain SIKE PF05769.11 OAJ20947.1 - 0.24 11.3 0.1 0.36 10.7 0.1 1.2 1 0 0 1 1 1 0 SIKE family DUF3437 PF11919.8 OAJ20948.1 - 8.7e-28 96.1 0.1 1.2e-25 89.2 0.1 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 OAJ20948.1 - 0.00075 19.8 0.2 0.1 13.0 0.0 4.1 3 2 2 5 5 5 1 HEAT repeats HEAT PF02985.22 OAJ20948.1 - 0.0024 18.0 0.0 0.33 11.3 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat TAF6_C PF07571.13 OAJ20948.1 - 0.071 13.4 0.6 1.8 8.9 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain DUF4404 PF14357.6 OAJ20948.1 - 0.76 10.4 3.5 2.9 8.6 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Nop PF01798.18 OAJ20949.1 - 1.4e-70 237.4 0.0 2.3e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAJ20949.1 - 1.6e-37 129.1 7.5 1.6e-37 129.1 7.5 2.1 2 0 0 2 2 2 1 Prp31 C terminal domain NOA36 PF06524.12 OAJ20949.1 - 0.7 9.2 18.0 1.3 8.3 18.0 1.3 1 0 0 1 1 1 0 NOA36 protein Rhomboid PF01694.22 OAJ20952.1 - 1.1e-27 96.9 11.2 1.1e-27 96.9 11.2 1.8 3 0 0 3 3 3 1 Rhomboid family Intg_mem_TP0381 PF09529.10 OAJ20952.1 - 0.068 12.7 2.9 0.49 9.9 0.8 2.8 3 1 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) zf-C2H2_2 PF12756.7 OAJ20953.1 - 8.5e-36 122.3 2.1 6e-28 97.1 0.0 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAJ20953.1 - 2.2e-09 37.3 12.0 1.3e-06 28.5 0.7 3.4 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ20953.1 - 6.2e-07 29.6 5.2 8.7e-07 29.1 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAJ20953.1 - 0.00041 20.9 10.6 0.35 11.8 0.1 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ20953.1 - 0.0068 16.4 2.4 0.25 11.4 0.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger DUF4674 PF15719.5 OAJ20953.1 - 0.12 12.4 6.0 0.37 10.8 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) DUF4551 PF15087.6 OAJ20953.1 - 0.25 10.1 7.5 0.44 9.3 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-C2H2 PF00096.26 OAJ20953.1 - 0.29 11.7 19.0 0.43 11.1 0.3 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type TFIIA PF03153.13 OAJ20953.1 - 0.96 9.4 16.5 1 9.3 14.6 2.0 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit TEX19 PF15553.6 OAJ20953.1 - 1.8 8.5 10.9 5 7.1 3.7 2.6 2 1 0 2 2 2 0 Testis-expressed protein 19 Abhydrolase_3 PF07859.13 OAJ20954.1 - 5.4e-40 137.5 0.7 2.7e-39 135.2 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAJ20954.1 - 4.3e-09 35.8 0.1 9.6e-09 34.6 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Lactamase_B_2 PF12706.7 OAJ20954.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain tRNA-synt_2 PF00152.20 OAJ20955.1 - 2e-71 240.7 0.0 2.7e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAJ20955.1 - 2.7e-15 56.2 0.1 4.5e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAJ20955.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ20955.1 - 0.01 15.3 0.2 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Acetyltransf_6 PF13480.7 OAJ20955.1 - 0.042 14.0 2.1 0.081 13.1 0.8 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 OAJ20957.1 - 2.7e-40 138.4 0.0 5.7e-24 84.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20957.1 - 1.1e-22 80.6 0.0 7.4e-16 58.2 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Serglycin PF04360.12 OAJ20957.1 - 0.023 14.6 7.3 0.077 12.9 7.3 1.9 1 0 0 1 1 1 0 Serglycin FhuF PF06276.12 OAJ20957.1 - 0.099 13.0 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Kinase-like PF14531.6 OAJ20957.1 - 0.11 11.8 0.0 1.1 8.6 0.0 2.0 1 1 0 1 1 1 0 Kinase-like LSM PF01423.22 OAJ20958.1 - 3e-15 55.7 0.0 4.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ20958.1 - 0.001 19.2 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 OAJ20958.1 - 0.06 13.5 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF4006 PF13179.6 OAJ20959.1 - 1.6 8.7 3.4 1.2 9.1 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Macoilin PF09726.9 OAJ20959.1 - 8.7 4.8 5.3 11 4.4 5.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4799 PF16056.5 OAJ21002.1 - 0.059 12.5 0.1 0.065 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) Xan_ur_permease PF00860.20 OAJ21003.1 - 6.9e-54 183.0 30.8 1.7e-52 178.4 30.8 2.1 1 1 0 1 1 1 1 Permease family TFIIA PF03153.13 OAJ21004.1 - 9.6e-50 170.8 7.5 3.8e-29 102.9 5.0 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 OAJ21005.1 - 3.4e-09 36.7 0.0 5.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ21005.1 - 0.00021 21.3 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cyclin_N PF00134.23 OAJ21008.1 - 2.7e-11 43.3 1.6 4.9e-11 42.5 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAJ21008.1 - 0.00042 20.3 0.4 0.001 19.0 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat SUIM_assoc PF16619.5 OAJ21008.1 - 0.04 14.0 3.6 0.16 12.0 3.6 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cyclin_C_2 PF16899.5 OAJ21008.1 - 0.2 12.1 0.8 0.67 10.4 0.2 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain Spt20 PF12090.8 OAJ21008.1 - 0.4 10.3 5.0 0.61 9.7 5.0 1.2 1 0 0 1 1 1 0 Spt20 family ERCC3_RAD25_C PF16203.5 OAJ21009.1 - 1.8e-122 407.3 0.0 3e-122 406.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAJ21009.1 - 2e-35 121.7 0.0 4.2e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ21009.1 - 2.3e-16 60.3 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ21009.1 - 2e-10 41.0 0.1 4.8e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAJ21009.1 - 8.5e-08 31.3 0.0 1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 OAJ21009.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.14 OAJ21009.1 - 5.8 5.1 7.7 9.3 4.4 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_A_bac PF01000.26 OAJ21010.1 - 1.1e-26 93.4 0.0 2.5e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAJ21010.1 - 2.5e-22 78.1 0.0 3.2e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 OAJ21010.1 - 0.022 14.5 0.0 0.086 12.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF22 Peptidase_M24 PF00557.24 OAJ21011.1 - 2.8e-50 170.9 0.0 4.1e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAJ21011.1 - 4.7e-40 136.2 0.0 1.2e-39 134.9 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 OAJ21011.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Creatinase_N_2 PF16189.5 OAJ21012.1 - 9.9e-44 149.3 0.0 5.2e-43 146.9 0.0 2.1 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAJ21012.1 - 1.6e-42 145.6 0.0 2.2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OAJ21012.1 - 4.5e-19 68.3 0.0 1.1e-17 63.8 0.0 2.7 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OAJ21012.1 - 7.1e-17 62.3 0.0 3.1e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Lipase_3 PF01764.25 OAJ21012.1 - 0.073 12.9 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) S4 PF01479.25 OAJ21013.1 - 3e-11 42.8 0.0 5.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OAJ21013.1 - 4e-10 40.5 0.1 5.3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Abhydrolase_3 PF07859.13 OAJ21014.1 - 1.6e-32 113.1 0.0 2e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ21014.1 - 0.03 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DLH PF01738.18 OAJ21014.1 - 0.084 12.4 0.1 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 OAJ21014.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OAJ21014.1 - 0.23 11.0 0.6 2.2 7.9 0.2 2.5 2 1 0 2 2 2 0 Putative esterase TRP PF06011.12 OAJ21015.1 - 3.4e-68 230.3 2.0 5.2e-68 229.7 2.0 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAJ21015.1 - 5.1e-29 101.4 0.1 7.7e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 OAJ21015.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ML domain LapA_dom PF06305.11 OAJ21015.1 - 1.5 8.7 10.3 0.39 10.6 0.2 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Ribosomal_L27 PF01016.19 OAJ21016.1 - 6e-35 119.1 0.3 1.1e-34 118.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF1180 PF06679.12 OAJ21016.1 - 0.94 9.9 6.5 0.64 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sin_N PF04801.13 OAJ21065.1 - 1.9e-19 70.2 0.0 1.6e-16 60.6 0.0 2.3 2 0 0 2 2 2 2 Sin-like protein conserved region RRM_1 PF00076.22 OAJ21066.1 - 3.2e-16 58.9 0.0 4.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ21066.1 - 3.7e-07 29.8 0.0 4.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MoaE PF02391.17 OAJ21067.1 - 2.1e-36 124.6 0.0 2.9e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 MoaE protein TOM13 PF08219.11 OAJ21068.1 - 2.7e-10 40.1 1.1 7.8e-10 38.6 1.1 1.9 1 1 0 1 1 1 1 Outer membrane protein TOM13 LAT PF15234.6 OAJ21068.1 - 0.006 16.3 0.9 0.006 16.3 0.9 1.9 2 0 0 2 2 2 1 Linker for activation of T-cells CENP-B_dimeris PF09026.10 OAJ21068.1 - 0.028 14.8 10.7 0.057 13.8 10.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 OAJ21068.1 - 0.067 11.9 0.2 0.089 11.5 0.2 1.2 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 OAJ21068.1 - 0.18 11.1 7.3 0.24 10.7 7.3 1.1 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 OAJ21068.1 - 0.42 10.6 5.2 0.57 10.1 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 OAJ21068.1 - 0.51 9.9 9.6 0.68 9.5 9.6 1.1 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 OAJ21068.1 - 0.63 10.1 8.9 1.7 8.6 8.9 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 OAJ21068.1 - 0.82 8.5 6.1 0.98 8.2 6.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.12 OAJ21068.1 - 2.5 6.2 10.0 3 5.9 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 OAJ21068.1 - 2.7 7.3 5.1 3.3 7.1 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-Tim10_DDP PF02953.15 OAJ21069.1 - 2.4e-20 72.0 1.0 2.9e-20 71.7 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger QCR10 PF09796.9 OAJ21070.1 - 2.5e-22 78.7 0.7 3.7e-22 78.1 0.4 1.4 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 OAJ21070.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Rep_fac_C PF08542.11 OAJ21071.1 - 4.1e-25 88.0 0.0 8.2e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAJ21071.1 - 2.4e-12 47.4 0.0 4.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ21071.1 - 4.2e-12 46.1 0.0 3.3e-10 40.0 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OAJ21071.1 - 3.2e-07 30.9 0.1 2.7e-05 24.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 OAJ21071.1 - 4.9e-06 26.4 0.0 8.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ21071.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ21071.1 - 2.8e-05 24.4 0.1 0.052 13.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 OAJ21071.1 - 0.00012 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 OAJ21071.1 - 0.00031 19.8 0.0 0.00062 18.8 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 OAJ21071.1 - 0.00032 20.5 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OAJ21071.1 - 0.00085 19.6 0.1 0.28 11.5 0.0 3.0 3 0 0 3 3 3 1 AAA C-terminal domain Viral_helicase1 PF01443.18 OAJ21071.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OAJ21071.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ21071.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OAJ21071.1 - 0.0092 15.9 0.0 0.073 13.0 0.0 2.1 1 1 1 2 2 2 1 NTPase DUF5119 PF17145.4 OAJ21071.1 - 0.011 15.6 0.0 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) Mg_chelatase PF01078.21 OAJ21071.1 - 0.015 14.7 0.0 0.11 11.9 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MipZ PF09140.11 OAJ21071.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ KTI12 PF08433.10 OAJ21071.1 - 0.03 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 OAJ21071.1 - 0.033 14.5 0.1 0.097 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAJ21071.1 - 0.034 13.5 0.0 8.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 OAJ21071.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAJ21071.1 - 0.038 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OAJ21071.1 - 0.048 13.3 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 OAJ21071.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 OAJ21071.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_11 PF13086.6 OAJ21071.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain B12-binding_2 PF02607.17 OAJ21071.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain DEAD PF00270.29 OAJ21071.1 - 0.14 11.9 0.1 0.47 10.2 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase DNA_pol3_delta PF06144.13 OAJ21071.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Mito_carr PF00153.27 OAJ21072.1 - 4.3e-35 119.5 6.8 1.4e-15 57.0 0.2 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ21072.1 - 0.97 8.5 0.0 0.97 8.5 0.0 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease RAP1 PF07218.11 OAJ21072.1 - 1.5 7.0 4.3 2 6.6 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 OAJ21072.1 - 6.9 5.6 7.0 11 5.0 7.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X ApbA_C PF08546.11 OAJ21073.1 - 8.8e-19 67.9 0.0 4.4e-09 36.6 0.0 3.1 4 1 0 4 4 4 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAJ21073.1 - 5.6e-16 58.6 0.0 1.3e-11 44.4 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 OAJ21076.1 - 2.6e-18 67.3 0.0 3.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ21076.1 - 1e-08 35.2 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ21076.1 - 0.053 13.0 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus RNase_PH PF01138.21 OAJ21077.1 - 2.5e-15 57.1 0.0 5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ADH_zinc_N_2 PF13602.6 OAJ21078.1 - 7.4e-18 65.9 0.0 1.9e-17 64.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ21078.1 - 8.7e-18 64.5 0.3 1.4e-17 63.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ21078.1 - 7.5e-09 35.4 0.0 2.1e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CMAS PF02353.20 OAJ21078.1 - 0.054 12.8 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SSB PF00436.25 OAJ21078.1 - 0.077 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Single-strand binding protein family Peptidase_S9_N PF02897.15 OAJ21079.1 - 1.9e-76 257.5 0.1 2.4e-76 257.2 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OAJ21079.1 - 8.3e-46 156.1 0.0 1.5e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Adap_comp_sub PF00928.21 OAJ21080.1 - 2.6e-37 128.7 0.0 8.3e-37 127.0 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family PX PF00787.24 OAJ21081.1 - 3.5e-19 68.8 0.0 6.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 PX domain SNF2_N PF00176.23 OAJ21082.1 - 1.1e-48 165.8 0.0 1.1e-48 165.8 0.0 3.0 3 1 1 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ21082.1 - 1.5e-17 63.9 0.0 5.7e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OAJ21082.1 - 3.5e-11 42.8 0.1 3.5e-11 42.8 0.1 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 OAJ21082.1 - 1.6e-08 34.4 0.2 0.0012 18.7 0.0 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 OAJ21082.1 - 8.7e-06 25.5 5.9 0.021 14.7 0.1 2.9 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAJ21082.1 - 0.00073 19.2 2.3 0.00073 19.2 2.3 5.0 5 0 0 5 5 5 2 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 OAJ21082.1 - 0.22 11.7 5.0 3.7 7.7 0.1 2.9 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 OAJ21082.1 - 3.8 7.7 8.9 22 5.3 1.7 3.6 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 OAJ21082.1 - 8.9 6.3 10.4 7.2 6.6 0.1 3.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MULE PF10551.9 OAJ21117.1 - 1.2e-22 80.1 0.0 3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ21117.1 - 9.4e-06 24.7 0.2 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.15 OAJ21117.1 - 0.25 12.1 1.7 0.62 10.8 1.7 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF3381 PF11861.8 OAJ21119.1 - 0.13 12.0 0.9 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) NAT PF04768.13 OAJ21120.1 - 1.6e-26 93.0 0.0 1.2e-17 64.1 0.0 2.5 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase CdiA_C_tRNase PF18664.1 OAJ21120.1 - 0.17 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain Adaptin_N PF01602.20 OAJ21122.1 - 4.9e-143 477.5 5.6 5.7e-143 477.2 5.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAJ21122.1 - 7.3e-25 87.4 4.0 1.5e-24 86.5 3.9 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAJ21122.1 - 7.3e-06 26.1 6.9 0.00026 21.1 0.5 3.3 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ21122.1 - 0.00033 21.0 2.0 3.3 8.2 0.2 4.6 4 1 0 4 4 4 2 HEAT repeats RIX1 PF08167.12 OAJ21122.1 - 0.0066 16.2 0.3 0.21 11.3 0.0 3.2 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 OAJ21122.1 - 0.076 13.3 0.2 1e+02 3.6 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat TGF_beta_GS PF08515.12 OAJ21122.1 - 0.092 12.3 0.3 0.3 10.6 0.3 2.0 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Peptidase_M73 PF12389.8 OAJ21122.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase RT_RNaseH PF17917.1 OAJ21123.1 - 1.4e-09 38.1 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ21123.1 - 7.3e-07 29.4 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ21123.1 - 0.00034 20.6 0.0 0.00082 19.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ21124.1 - 1.3e-26 93.6 0.0 1.9e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F8 PF05886.11 OAJ21125.1 - 0.0067 16.5 6.0 0.14 12.3 1.9 3.3 2 0 0 2 2 2 2 Orthopoxvirus F8 protein Orn_Arg_deC_N PF02784.16 OAJ21126.1 - 1e-24 87.3 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 OAJ21126.1 - 0.0069 16.6 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Phos_pyr_kin PF08543.12 OAJ21127.1 - 1.1e-69 234.6 0.1 2.7e-52 177.6 0.1 3.2 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OAJ21127.1 - 5.5e-25 88.4 0.5 3.8e-24 85.7 0.5 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 OAJ21127.1 - 0.0097 15.3 0.9 0.98 8.7 0.0 2.6 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.24 OAJ21127.1 - 0.055 12.8 0.2 1.6 8.0 0.0 2.7 3 0 0 3 3 3 0 pfkB family carbohydrate kinase Cyclin_C PF02984.19 OAJ21127.1 - 0.17 12.0 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Peptidase_M43 PF05572.13 OAJ21128.1 - 1.1e-14 54.7 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ21128.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ21128.1 - 0.0019 18.4 1.4 0.0048 17.1 1.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 OAJ21128.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Peptidase_M10 PF00413.24 OAJ21128.1 - 0.012 15.4 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 OAJ21128.1 - 0.018 14.7 0.8 0.047 13.3 0.8 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 OAJ21129.1 - 4.9e-16 59.0 0.0 7.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ21129.1 - 4.6e-06 27.1 0.0 9.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ21129.1 - 4.5e-05 23.7 1.0 6.3e-05 23.2 1.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAJ21129.1 - 0.0001 22.0 0.3 0.00028 20.6 0.3 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ21129.1 - 0.024 14.5 0.1 0.045 13.6 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.11 OAJ21129.1 - 0.033 14.2 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 OAJ21129.1 - 0.052 12.8 0.2 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Met-zincin Metallophos PF00149.28 OAJ21172.1 - 1.5e-08 35.4 1.5 2.5e-08 34.7 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Myc_target_1 PF15179.6 OAJ21172.1 - 0.19 11.6 3.8 0.36 10.7 3.8 1.3 1 0 0 1 1 1 0 Myc target protein 1 PseudoU_synth_1 PF01416.20 OAJ21173.1 - 5.9e-24 84.6 0.3 2.7e-20 72.9 0.1 3.6 3 1 0 3 3 3 2 tRNA pseudouridine synthase TT_ORF2 PF02957.15 OAJ21173.1 - 2.9 8.8 5.5 6.5 7.7 0.5 2.9 2 0 0 2 2 2 0 TT viral ORF2 CBF PF03914.17 OAJ21176.1 - 2.1e-22 80.0 0.1 7.3e-22 78.2 0.1 2.0 1 0 0 1 1 1 1 CBF/Mak21 family AIM5 PF17050.5 OAJ21176.1 - 0.011 16.5 0.1 0.075 13.9 0.1 2.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 KRAB PF01352.27 OAJ21177.1 - 0.21 11.3 0.7 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 KRAB box VIR_N PF15912.5 OAJ21177.1 - 0.62 9.6 0.0 0.62 9.6 0.0 3.1 2 1 1 3 3 3 0 Virilizer, N-terminal WLM PF08325.10 OAJ21178.1 - 4.2e-47 160.7 0.0 1e-46 159.4 0.0 1.7 2 0 0 2 2 2 1 WLM domain YL1 PF05764.13 OAJ21179.1 - 0.44 10.6 17.3 0.042 14.0 7.9 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Casc1 PF12366.8 OAJ21179.1 - 8.4 5.8 9.5 5.8 6.4 1.0 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Acetyltransf_1 PF00583.25 OAJ21180.1 - 9.7e-07 29.0 0.0 0.0028 17.9 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ21180.1 - 9e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ21180.1 - 4.8e-05 23.3 0.0 0.034 14.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ21180.1 - 0.048 13.7 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SDA1 PF05285.12 OAJ21180.1 - 0.066 12.6 24.5 0.21 11.0 4.5 3.2 3 0 0 3 3 3 0 SDA1 FR47 PF08445.10 OAJ21180.1 - 0.15 12.1 0.0 6.7 6.8 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_8 PF13523.6 OAJ21180.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Spt5_N PF11942.8 OAJ21180.1 - 0.41 11.7 32.8 0.62 11.1 7.1 4.6 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.12 OAJ21180.1 - 2.5 6.2 21.7 1.9 6.6 3.0 3.1 3 0 0 3 3 3 0 Nop14-like family Sas10_Utp3 PF04000.15 OAJ21181.1 - 3.7e-08 33.9 0.4 1e-07 32.5 0.4 1.8 1 1 0 1 1 1 1 Sas10/Utp3/C1D family TMEM51 PF15345.6 OAJ21181.1 - 0.037 13.9 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 Actino_peptide PF14408.6 OAJ21181.1 - 0.15 12.2 4.2 0.21 11.7 0.9 2.7 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes tRNA-synt_2 PF00152.20 OAJ21182.1 - 4.9e-76 255.8 0.1 6.4e-76 255.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ21182.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ21182.1 - 0.065 12.7 0.5 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) APG6_N PF17675.1 OAJ21183.1 - 1.3 9.5 3.2 0.54 10.8 0.8 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region PAP2 PF01569.21 OAJ21184.1 - 5e-12 45.8 3.0 5.7e-11 42.3 3.0 2.2 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 OAJ21184.1 - 0.036 14.2 2.1 0.25 11.5 0.1 2.5 2 2 0 2 2 2 0 Divergent PAP2 family DUF2517 PF10725.9 OAJ21184.1 - 0.051 13.3 0.4 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) SNF2_N PF00176.23 OAJ21185.1 - 9.2e-70 235.1 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAJ21185.1 - 9.5e-19 67.1 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAJ21185.1 - 1.3e-16 60.9 0.0 2.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ21185.1 - 7e-07 29.4 0.0 8.8e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 OAJ21185.1 - 0.00039 20.2 11.3 0.00071 19.4 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ21185.1 - 0.0018 18.1 13.8 0.0032 17.3 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ21185.1 - 0.029 14.7 13.9 0.054 13.8 13.9 1.5 1 0 0 1 1 1 0 Ring finger domain Ribosomal_L23eN PF03939.13 OAJ21185.1 - 0.035 14.3 5.3 0.11 12.8 5.3 1.9 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain zf-RING_5 PF14634.6 OAJ21185.1 - 0.09 12.8 14.3 0.16 11.9 14.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ21185.1 - 0.61 10.0 13.1 1.2 9.0 13.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L22e PF01776.17 OAJ21186.1 - 1.8e-44 150.6 0.1 2e-44 150.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family NIF PF03031.18 OAJ21187.1 - 3.4e-19 69.2 0.0 1.5e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase BRCT PF00533.26 OAJ21187.1 - 8.5e-06 26.1 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ21187.1 - 2.3e-05 24.2 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain SDA1 PF05285.12 OAJ21187.1 - 0.0047 16.4 3.3 0.0047 16.4 3.3 3.3 3 0 0 3 3 3 2 SDA1 Ustilago_mating PF05722.12 OAJ21187.1 - 0.29 10.6 5.7 0.03 13.9 1.0 1.7 2 0 0 2 2 2 0 Ustilago B locus mating-type protein UQ_con PF00179.26 OAJ21232.1 - 3.2e-47 159.7 0.0 3.7e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ21232.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAJ21232.1 - 0.024 14.5 0.1 0.049 13.5 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OAJ21232.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Pkinase PF00069.25 OAJ21233.1 - 3.6e-67 226.5 0.0 7.5e-67 225.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21233.1 - 7.8e-50 169.6 0.0 1.3e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ21233.1 - 0.00013 20.9 0.0 0.00013 20.9 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ21233.1 - 0.029 13.3 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 OAJ21233.1 - 0.13 12.3 16.1 0.18 11.8 16.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 OAJ21233.1 - 0.27 10.5 1.9 0.85 8.9 0.0 2.6 4 0 0 4 4 4 0 Kinase-like SOG2 PF10428.9 OAJ21233.1 - 1.5 7.9 16.1 2.1 7.4 16.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Asp PF00026.23 OAJ21234.1 - 6.6e-43 147.3 0.0 8.4e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21234.1 - 4.7e-10 40.0 2.9 5.9e-09 36.4 1.5 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal PHD PF00628.29 OAJ21235.1 - 8.2e-07 28.8 13.9 1.4e-06 28.0 13.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ21235.1 - 0.13 11.8 4.6 0.23 11.1 4.6 1.3 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 OAJ21235.1 - 0.38 10.8 3.7 0.81 9.8 3.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger SET PF00856.28 OAJ21235.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.4 3 2 0 3 3 3 0 SET domain HEAT PF02985.22 OAJ21236.1 - 9.1e-05 22.4 6.5 0.72 10.3 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OAJ21236.1 - 0.00031 21.1 0.5 0.029 14.8 0.1 5.1 5 1 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 OAJ21236.1 - 0.00044 20.3 1.8 0.0076 16.3 0.0 3.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Het-C PF07217.11 OAJ21236.1 - 0.075 11.6 0.1 0.18 10.3 0.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C HEAT_EZ PF13513.6 OAJ21236.1 - 0.29 11.7 4.2 73 4.0 0.0 4.9 4 0 0 4 4 4 0 HEAT-like repeat Actin PF00022.19 OAJ21237.1 - 1e-127 426.2 0.0 5e-127 423.9 0.0 1.8 1 1 0 1 1 1 1 Actin Rad21_Rec8 PF04824.16 OAJ21237.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Sec63 PF02889.16 OAJ21238.1 - 9.1e-149 493.6 0.0 8e-82 274.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAJ21238.1 - 1.5e-42 145.3 0.0 9e-25 87.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAJ21238.1 - 5.6e-37 126.3 0.2 1.7e-36 124.8 0.2 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 OAJ21238.1 - 5.6e-20 72.0 0.0 8.3e-15 55.2 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ21238.1 - 1.5e-11 44.7 0.0 1.2e-07 32.0 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAJ21238.1 - 1.9e-06 27.7 0.1 0.0053 16.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAJ21238.1 - 2.7e-05 24.4 0.1 0.019 15.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 OAJ21238.1 - 0.071 12.6 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Mis14 PF08641.12 OAJ21239.1 - 3.7e-09 37.0 1.5 3.7e-09 37.0 1.5 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like RNA_pol_Rpb2_6 PF00562.28 OAJ21240.1 - 7.3e-127 423.6 0.1 1.1e-126 423.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ21240.1 - 2.3e-59 200.3 0.1 3.6e-59 199.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAJ21240.1 - 1.5e-33 116.0 0.2 3.1e-33 115.0 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ21240.1 - 1.4e-29 102.4 0.1 3.3e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 OAJ21240.1 - 3.6e-25 88.0 0.3 8e-25 86.9 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAJ21240.1 - 2.1e-20 72.6 0.0 4.9e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAJ21240.1 - 4.7e-09 36.7 1.7 1.8e-08 34.8 1.7 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Aldo_ket_red PF00248.21 OAJ21240.1 - 0.046 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family UQ_con PF00179.26 OAJ21241.1 - 3.8e-22 78.4 0.0 7.6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ21241.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain IBR PF01485.21 OAJ21241.1 - 0.019 15.2 0.5 0.047 13.9 0.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ALMT PF11744.8 OAJ21241.1 - 0.82 8.4 2.3 1.4 7.6 2.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter WD40 PF00400.32 OAJ21242.1 - 2e-09 37.9 9.8 0.019 15.8 1.0 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat OEP PF02321.18 OAJ21242.1 - 0.0051 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein Sugar_tr PF00083.24 OAJ21281.1 - 3.6e-46 158.0 13.6 4.9e-46 157.5 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ21281.1 - 2.5e-24 85.9 25.1 2.4e-14 53.0 13.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Peptidase_S24 PF00717.23 OAJ21281.1 - 0.00022 21.1 0.1 0.001 19.0 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like OATP PF03137.20 OAJ21281.1 - 0.19 10.0 2.6 0.97 7.6 0.1 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tudor_3 PF18115.1 OAJ21282.1 - 0.00017 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain SMN PF06003.12 OAJ21282.1 - 0.00055 19.3 0.0 0.00055 19.3 0.0 1.9 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) LBR_tudor PF09465.10 OAJ21282.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PWWP PF00855.17 OAJ21282.1 - 0.0015 18.8 0.7 0.19 12.1 0.7 2.4 1 1 0 1 1 1 1 PWWP domain TUDOR PF00567.24 OAJ21282.1 - 0.0035 17.4 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Tudor_2 PF18104.1 OAJ21282.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain BRF1 PF07741.13 OAJ21282.1 - 0.22 11.9 4.0 19 5.7 3.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NAM-associated PF14303.6 OAJ21282.1 - 0.29 11.8 10.3 0.55 10.9 10.3 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SPX PF03105.19 OAJ21283.1 - 0.3 11.0 43.8 0.17 11.7 7.9 2.4 2 0 0 2 2 2 0 SPX domain Trypsin_2 PF13365.6 OAJ21284.1 - 0.0001 23.3 0.0 0.028 15.3 0.0 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain UCH PF00443.29 OAJ21285.1 - 3.2e-42 144.8 0.0 5.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ21285.1 - 1.1e-21 76.9 5.9 2.2e-18 66.3 1.5 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 OAJ21285.1 - 1.6e-19 69.4 1.3 2.7e-10 39.9 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 OAJ21285.1 - 1.9e-18 66.0 10.1 5.5e-17 61.3 4.8 3.7 2 1 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 OAJ21285.1 - 3.2e-18 66.4 0.0 3.1e-17 63.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Misat_Tub_SegII PF10644.9 OAJ21285.1 - 0.056 13.7 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain LIAS_N PF16881.5 OAJ21286.1 - 1.8e-15 57.3 0.2 6.3e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAJ21286.1 - 3.6e-14 53.5 0.1 5.7e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ABC_tran PF00005.27 OAJ21287.1 - 2e-14 54.2 0.0 1.6e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ21287.1 - 3.4e-07 30.4 2.0 0.0015 18.4 0.5 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ21287.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ21287.1 - 0.0036 17.8 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ21287.1 - 0.0041 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 OAJ21287.1 - 0.0042 17.3 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 OAJ21287.1 - 0.012 15.2 0.2 0.074 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAJ21287.1 - 0.013 15.3 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 OAJ21287.1 - 0.024 14.1 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 OAJ21287.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.10 OAJ21287.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.21 OAJ21287.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase AAA_16 PF13191.6 OAJ21287.1 - 0.059 13.8 0.3 0.092 13.1 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 OAJ21287.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 OAJ21287.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ21287.1 - 0.085 13.0 0.1 0.22 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAJ21287.1 - 0.11 12.7 0.0 0.46 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 OAJ21287.1 - 0.14 12.6 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 OAJ21287.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OAJ21287.1 - 0.2 11.2 0.2 0.32 10.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rhomboid PF01694.22 OAJ21290.1 - 1.3e-24 86.9 1.1 2.2e-24 86.2 1.1 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OAJ21290.1 - 0.0029 18.1 0.1 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) adh_short PF00106.25 OAJ21291.1 - 2.1e-18 66.5 0.0 1.5e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ21291.1 - 1.7e-11 44.1 0.0 7.4e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ21291.1 - 0.00047 20.1 0.1 0.00066 19.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ21291.1 - 0.0043 16.5 0.1 0.027 13.9 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ21291.1 - 0.0063 16.0 0.4 0.066 12.6 0.0 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAJ21291.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HECT PF00632.25 OAJ21292.1 - 6.6e-97 324.7 0.0 8.4e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Tau95 PF09734.9 OAJ21292.1 - 0.14 13.0 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PfkB PF00294.24 OAJ21293.1 - 2.6e-40 138.6 0.1 3.4e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RabGAP-TBC PF00566.18 OAJ21294.1 - 2.3e-49 167.9 0.0 4.3e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Metal_resist PF13801.6 OAJ21294.1 - 4.9 7.4 10.2 0.93 9.7 2.1 3.1 3 0 0 3 3 3 0 Heavy-metal resistance Aldedh PF00171.22 OAJ21340.1 - 3.4e-145 484.1 0.3 3.8e-145 483.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SIS PF01380.22 OAJ21342.1 - 4.6e-65 217.4 0.2 6e-36 123.2 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAJ21342.1 - 1.9e-15 57.2 0.0 4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ21342.1 - 1.3e-11 44.4 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAJ21342.1 - 0.0022 17.0 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TTRAP PF14203.6 OAJ21342.1 - 0.03 14.3 0.3 0.19 11.7 0.1 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein SIS_2 PF13580.6 OAJ21342.1 - 0.083 12.9 0.0 0.92 9.5 0.0 2.7 3 1 1 4 4 4 0 SIS domain YoeB_toxin PF06769.14 OAJ21342.1 - 0.19 11.8 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system UTP25 PF06862.12 OAJ21343.1 - 2e-142 475.3 0.0 3.4e-142 474.6 0.0 1.3 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TFIIA PF03153.13 OAJ21343.1 - 0.019 15.0 9.3 0.027 14.5 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AICARFT_IMPCHas PF01808.18 OAJ21344.1 - 4e-84 282.6 0.3 5.6e-84 282.1 0.3 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAJ21344.1 - 1.4e-21 76.5 0.0 2.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain SET PF00856.28 OAJ21345.1 - 3.2e-06 27.6 0.0 0.00015 22.2 0.0 2.7 1 1 0 1 1 1 1 SET domain PAP1 PF08601.10 OAJ21345.1 - 0.19 11.4 4.5 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 GATase_6 PF13522.6 OAJ21347.1 - 4.8e-16 59.2 0.0 7.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ21347.1 - 4.2e-12 46.1 0.0 6.7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAJ21347.1 - 0.00056 18.9 0.0 0.00082 18.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS PF01380.22 OAJ21347.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 SIS domain RNA_pol_Rpb6 PF01192.22 OAJ21348.1 - 0.0087 16.0 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb6 CAP PF00188.26 OAJ21348.1 - 0.02 15.7 0.1 0.063 14.1 0.1 1.8 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF659 PF04937.15 OAJ21348.1 - 0.041 13.7 0.3 0.12 12.2 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) BUD22 PF09073.10 OAJ21348.1 - 1.9 7.7 13.6 3.5 6.9 13.6 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ21348.1 - 7.7 4.6 15.5 12 4.0 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family Peptidase_M16_M PF16187.5 OAJ21349.1 - 7.1e-86 288.0 0.0 1.2e-85 287.2 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OAJ21349.1 - 3.6e-41 140.6 0.1 2.8e-40 137.7 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ21349.1 - 5.7e-35 121.0 0.1 3.9e-20 72.6 0.0 3.7 4 1 0 4 4 4 2 Peptidase M16 inactive domain Coagulin PF02035.15 OAJ21349.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Coagulin P16-Arc PF04699.14 OAJ21350.1 - 1e-49 168.8 0.0 1.2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF5102 PF17104.5 OAJ21351.1 - 1.5e-18 67.9 5.4 3.4e-18 66.7 5.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) zf-RING_11 PF17123.5 OAJ21351.1 - 0.00011 21.8 3.2 0.07 12.9 0.2 2.4 2 0 0 2 2 2 2 RING-like zinc finger EI24 PF07264.11 OAJ21351.1 - 1.8 8.8 9.4 0.64 10.2 5.3 2.2 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DAGK_cat PF00781.24 OAJ21353.1 - 4.5e-12 45.7 0.0 1.7e-11 43.8 0.0 1.9 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain FMO-like PF00743.19 OAJ21401.1 - 4.6e-18 64.9 0.0 2.2e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAJ21401.1 - 4.8e-08 32.6 0.0 0.00087 18.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ21401.1 - 2.5e-07 30.3 0.0 8.7e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ21401.1 - 5.3e-06 26.5 0.2 0.0002 21.4 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAJ21401.1 - 0.00069 19.3 0.1 0.0051 16.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ21401.1 - 0.0021 17.3 0.0 0.04 13.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ21401.1 - 0.0025 18.0 0.0 0.0064 16.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RNA_pol_Rpc4 PF05132.14 OAJ21402.1 - 5.8e-23 82.0 1.1 5.8e-23 82.0 1.1 5.3 5 1 0 5 5 5 1 RNA polymerase III RPC4 Leo1 PF04004.13 OAJ21402.1 - 0.057 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Leo1-like protein Metal_resist PF13801.6 OAJ21403.1 - 0.0086 16.3 1.8 0.0086 16.3 1.8 2.4 2 0 0 2 2 2 1 Heavy-metal resistance Med9 PF07544.13 OAJ21403.1 - 0.05 13.7 0.1 0.05 13.7 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 OEP PF02321.18 OAJ21403.1 - 0.061 13.1 0.3 0.061 13.1 0.3 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein PRP38 PF03371.15 OAJ21404.1 - 3e-59 199.8 0.3 3.7e-59 199.5 0.3 1.1 1 0 0 1 1 1 1 PRP38 family Adeno_VII PF03228.14 OAJ21404.1 - 0.058 14.0 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 Adenoviral core protein VII Cwf_Cwc_15 PF04889.12 OAJ21404.1 - 0.98 9.1 16.1 0.041 13.6 7.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TMA7 PF09072.10 OAJ21405.1 - 0.096 13.5 0.1 0.13 13.1 0.1 1.2 1 0 0 1 1 1 0 Translation machinery associated TMA7 ABM PF03992.16 OAJ21406.1 - 2.9e-08 33.7 0.1 3.6e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABC_tran PF00005.27 OAJ21407.1 - 7.4e-33 114.0 0.0 1.5e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAJ21407.1 - 9.1e-32 110.8 4.6 2e-31 109.6 4.6 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 OAJ21407.1 - 0.0012 19.3 0.2 0.0043 17.4 0.2 2.0 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 OAJ21407.1 - 0.0012 18.3 0.0 0.033 13.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ21407.1 - 0.0035 17.3 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OAJ21407.1 - 0.0036 17.6 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OAJ21407.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAJ21407.1 - 0.037 13.8 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system HpcH_HpaI PF03328.14 OAJ21408.1 - 7.9e-38 129.8 0.1 3.8e-37 127.6 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAJ21408.1 - 2e-08 33.8 0.0 0.00084 18.6 0.0 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PLDc_2 PF13091.6 OAJ21410.1 - 8.2e-18 64.6 0.0 2.6e-07 30.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAJ21410.1 - 2.2e-15 56.1 0.6 9.8e-07 28.7 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 OAJ21410.1 - 0.037 13.2 0.4 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Y_phosphatase PF00102.27 OAJ21411.1 - 4e-52 177.1 0.1 9.7e-45 152.9 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAJ21411.1 - 0.0023 18.4 0.0 0.037 14.5 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 OAJ21411.1 - 0.016 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAJ21411.1 - 0.031 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Dicty_REP PF05086.12 OAJ21411.1 - 0.3 9.0 2.2 0.58 8.1 2.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pyridoxal_deC PF00282.19 OAJ21412.1 - 2.9e-94 315.9 0.0 5e-63 213.1 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 OAJ21412.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II HflK_N PF12221.8 OAJ21412.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Aminotran_5 PF00266.19 OAJ21412.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V ResB PF05140.14 OAJ21413.1 - 0.17 10.6 1.5 0.21 10.3 1.5 1.0 1 0 0 1 1 1 0 ResB-like family TetR_C_33 PF13305.6 OAJ21413.1 - 0.19 12.5 3.9 0.27 12.0 3.8 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Asp PF00026.23 OAJ21414.1 - 1e-48 166.4 0.1 5e-48 164.1 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21414.1 - 1.1e-06 29.0 0.3 0.024 14.9 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ21414.1 - 1.1e-05 26.0 0.6 0.061 14.0 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease Arv1 PF04161.13 OAJ21415.1 - 5.7e-25 88.7 0.4 2.3e-19 70.4 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family Dor1 PF04124.12 OAJ21463.1 - 0.1 11.3 5.8 0.37 9.4 0.9 2.6 3 0 0 3 3 3 0 Dor1-like family Herpes_capsid PF06112.11 OAJ21463.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.3 1 1 1 2 2 2 0 Gammaherpesvirus capsid protein G-patch PF01585.23 OAJ21464.1 - 7.3e-06 25.8 0.2 1.7e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 OAJ21464.1 - 0.0096 16.2 4.0 0.016 15.5 4.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 OAJ21464.1 - 0.015 15.1 0.1 0.015 15.1 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Rpr2 PF04032.16 OAJ21466.1 - 0.0045 17.2 0.1 0.044 14.1 0.1 2.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain WD40 PF00400.32 OAJ21467.1 - 2.9e-07 31.1 9.0 0.00074 20.3 0.4 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21467.1 - 0.0002 21.6 0.0 0.12 12.6 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA_Me_trans PF03054.16 OAJ21468.1 - 5.7e-93 311.5 0.0 8.3e-81 271.5 0.0 2.9 2 1 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 OAJ21468.1 - 1.4e-05 24.3 0.0 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 OAJ21468.1 - 0.0041 16.7 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Mitoc_mL59 PF18126.1 OAJ21469.1 - 2.3e-27 95.8 14.5 5.4e-27 94.6 14.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Mcm10 PF09332.11 OAJ21470.1 - 0.0083 15.6 2.2 0.013 15.0 2.2 1.2 1 0 0 1 1 1 1 Mcm10 replication factor Borrelia_P83 PF05262.11 OAJ21470.1 - 0.014 13.9 3.1 0.017 13.6 3.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Uds1 PF15456.6 OAJ21470.1 - 0.089 13.0 5.6 0.15 12.2 5.6 1.3 1 0 0 1 1 1 0 Up-regulated During Septation WDCP PF15390.6 OAJ21470.1 - 0.17 10.2 0.4 0.25 9.7 0.4 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Tho2 PF11262.8 OAJ21470.1 - 0.19 10.9 3.8 0.28 10.3 3.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1764 PF08576.10 OAJ21470.1 - 0.21 12.5 4.5 0.56 11.1 4.5 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Casc1_N PF15927.5 OAJ21470.1 - 0.21 11.2 10.0 0.34 10.6 10.0 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3584 PF12128.8 OAJ21470.1 - 0.3 8.6 5.6 0.42 8.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 OAJ21470.1 - 0.32 10.2 1.6 0.45 9.7 1.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Med30 PF11315.8 OAJ21470.1 - 0.34 11.1 3.7 0.58 10.3 3.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 HemX PF04375.14 OAJ21470.1 - 0.77 9.0 4.4 1.4 8.2 4.4 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Seryl_tRNA_N PF02403.22 OAJ21470.1 - 2 8.7 9.5 4.4 7.6 9.5 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 OAJ21470.1 - 2.8 7.2 8.7 4.6 6.5 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 OAJ21470.1 - 3 7.1 12.8 4.8 6.5 12.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DNA_pol_phi PF04931.13 OAJ21471.1 - 0.009 14.2 19.6 0.012 13.8 19.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi YL1 PF05764.13 OAJ21471.1 - 0.021 15.0 33.0 0.041 14.0 33.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DUF1822 PF08852.11 OAJ21471.1 - 0.045 12.8 0.0 0.045 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) CDC45 PF02724.14 OAJ21471.1 - 0.75 8.0 25.0 1.2 7.3 25.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 OAJ21471.1 - 0.9 8.9 38.9 1.4 8.2 38.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Raftlin PF15250.6 OAJ21471.1 - 4.2 6.0 12.1 5 5.8 11.4 1.4 1 1 0 1 1 1 0 Raftlin eIF3_subunit PF08597.10 OAJ21471.1 - 4.8 7.0 37.3 8.7 6.2 37.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CENP-B_dimeris PF09026.10 OAJ21471.1 - 5 7.6 16.8 36 4.8 17.1 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myc_N PF01056.18 OAJ21472.1 - 0.016 15.1 1.4 0.025 14.5 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pep3_Vps18 PF05131.14 OAJ21473.1 - 1.7e-46 157.8 0.0 4.7e-46 156.3 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAJ21473.1 - 3.4e-08 33.5 8.4 5.9e-07 29.5 0.3 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 OAJ21473.1 - 0.00016 21.2 0.7 0.00053 19.5 0.7 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OAJ21473.1 - 0.00074 19.5 2.4 0.00074 19.5 2.4 1.9 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 OAJ21473.1 - 0.0012 18.7 1.0 0.003 17.5 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ21473.1 - 0.034 14.0 1.9 0.089 12.7 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 OAJ21473.1 - 0.059 13.8 0.6 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 OAJ21473.1 - 0.079 13.3 3.9 0.048 14.0 1.2 2.0 2 0 0 2 2 2 0 Ring finger domain DUF2175 PF09943.9 OAJ21473.1 - 0.2 12.0 1.9 0.89 9.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) RRM_1 PF00076.22 OAJ21474.1 - 4.4e-19 68.1 0.0 6.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ21474.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif MID_MedPIWI PF18296.1 OAJ21475.1 - 0.0011 18.9 0.9 0.0015 18.4 0.9 1.3 1 0 0 1 1 1 1 MID domain of medPIWI FUSC PF04632.12 OAJ21475.1 - 2.8 6.4 10.7 0.15 10.5 2.9 2.2 2 1 0 2 2 2 0 Fusaric acid resistance protein family Kelch_4 PF13418.6 OAJ21476.1 - 1.2e-34 118.1 11.6 1.1e-05 25.4 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ21476.1 - 3.4e-29 100.2 4.5 9.4e-06 25.1 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 OAJ21476.1 - 8.5e-28 95.9 7.0 2.9e-06 27.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OAJ21476.1 - 4.5e-24 84.2 17.1 1.7e-06 28.2 0.3 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ21476.1 - 4e-23 80.9 5.3 0.0002 21.5 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OAJ21476.1 - 3.6e-22 77.4 8.8 5.3e-05 23.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Adaptin_N PF01602.20 OAJ21477.1 - 2.3e-55 188.2 0.0 1e-32 113.4 0.0 3.2 3 0 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 OAJ21477.1 - 1.9e-10 41.0 0.0 9.3e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ21477.1 - 2.4e-05 24.2 4.4 1.5 9.3 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OAJ21477.1 - 3.8e-05 24.0 3.5 3.8e-05 24.0 3.5 5.5 6 2 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 OAJ21477.1 - 7e-05 23.2 1.4 7e-05 23.2 1.4 5.3 3 1 2 5 5 5 2 HEAT-like repeat Myc_N PF01056.18 OAJ21477.1 - 0.0054 16.7 1.3 0.0054 16.7 1.3 3.5 3 0 0 3 3 3 1 Myc amino-terminal region CTNNBL PF08216.11 OAJ21478.1 - 7.8e-33 112.8 0.3 2.7e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.6 OAJ21478.1 - 0.019 15.3 2.0 0.43 11.0 0.2 3.6 2 0 0 2 2 2 0 HEAT repeats Arm PF00514.23 OAJ21478.1 - 0.085 12.9 1.9 2 8.6 0.1 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAJ21478.1 - 0.1 12.9 0.6 4.7 7.7 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat Pox_E10 PF04805.12 OAJ21478.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 E10-like protein conserved region NAM-associated PF14303.6 OAJ21478.1 - 5.2 7.8 8.0 1.4 9.6 2.0 2.7 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain AT_hook PF02178.19 OAJ21479.1 - 0.0073 16.1 21.0 0.072 13.0 4.6 3.1 2 0 0 2 2 2 2 AT hook motif RVT_1 PF00078.27 OAJ21517.1 - 5.3e-30 104.6 0.0 7.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-SNARE_C PF12352.8 OAJ21518.1 - 3.3e-13 49.7 0.3 7.7e-13 48.5 0.3 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAJ21518.1 - 4.5e-06 26.5 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Sec20 DSPn PF14671.6 OAJ21519.1 - 4e-33 114.8 0.0 5.2e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAJ21519.1 - 1.2e-12 47.7 0.0 2.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ21519.1 - 0.00024 20.8 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAJ21519.1 - 0.008 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate COG2 PF06148.11 OAJ21519.1 - 0.39 10.8 1.5 0.75 9.9 1.5 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sld5 PF05916.11 OAJ21520.1 - 1.2e-20 73.9 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FMN_dh PF01070.18 OAJ21521.1 - 4.5e-117 391.0 0.0 5.4e-117 390.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAJ21521.1 - 1.5e-20 73.1 0.2 3.8e-20 71.8 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAJ21521.1 - 8.4e-06 25.2 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAJ21521.1 - 0.00055 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAJ21521.1 - 0.015 14.7 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 OAJ21521.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Vps5 PF09325.10 OAJ21521.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Nop14 PF04147.12 OAJ21522.1 - 0.0056 15.0 3.6 0.0087 14.3 3.6 1.2 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.18 OAJ21522.1 - 0.15 12.0 5.2 0.26 11.2 4.7 1.3 1 1 0 1 1 1 0 Myc amino-terminal region dCMP_cyt_deam_1 PF00383.23 OAJ21523.1 - 1.7e-06 27.8 3.6 0.12 12.3 4.9 3.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region F-box-like PF12937.7 OAJ21524.1 - 0.00012 21.9 0.2 0.0043 16.9 0.0 3.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ21524.1 - 0.31 11.0 2.0 4 7.4 0.3 2.4 2 0 0 2 2 2 0 F-box domain DUF3632 PF12311.8 OAJ21524.1 - 3.9 7.9 5.1 19 5.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3632) Aldedh PF00171.22 OAJ21525.1 - 6.4e-178 592.0 0.9 7.2e-178 591.8 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.18 OAJ21527.1 - 8.9e-13 48.3 8.9 2.6e-12 46.8 8.9 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 OAJ21528.1 - 1.8e-17 62.9 0.0 4.3e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ21528.1 - 0.037 14.1 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif OB_RNB PF08206.11 OAJ21528.1 - 0.086 12.5 0.3 0.34 10.6 0.3 1.8 1 1 0 1 1 1 0 Ribonuclease B OB domain RRM_occluded PF16842.5 OAJ21528.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DbpA PF03880.15 OAJ21528.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_5 PF13893.6 OAJ21528.1 - 0.25 10.9 0.0 0.34 10.5 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_1 PF00018.28 OAJ21529.1 - 6e-14 51.4 0.4 1.7e-06 27.5 0.1 3.1 3 0 0 3 3 3 2 SH3 domain RA PF00788.23 OAJ21529.1 - 6.5e-11 42.7 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 OAJ21529.1 - 6e-10 39.1 0.0 9.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ21529.1 - 2.2e-09 37.6 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 OAJ21529.1 - 8.8e-08 31.9 4.6 0.0052 16.6 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 OAJ21529.1 - 9.5e-05 22.0 1.3 0.14 11.9 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain SAM_PNT PF02198.16 OAJ21529.1 - 0.24 11.4 0.0 0.94 9.5 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain PET117 PF15786.5 OAJ21530.1 - 1.9e-18 66.5 4.8 8.3e-18 64.4 4.8 1.9 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial TFIIA PF03153.13 OAJ21530.1 - 0.42 10.6 14.3 0.44 10.5 14.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 OAJ21530.1 - 1.1 8.4 11.1 1.2 8.3 11.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Stm1_N PF09598.10 OAJ21530.1 - 2.4 9.1 14.3 0.39 11.6 10.3 1.8 2 1 0 2 2 2 0 Stm1 DUF4050 PF13259.6 OAJ21531.1 - 0.29 11.5 2.8 0.87 9.9 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) NAP PF00956.18 OAJ21532.1 - 4e-22 78.7 3.8 5.6e-20 71.6 0.6 2.6 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 OAJ21532.1 - 1.3 9.2 7.4 0.2 11.9 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TFA2_Winged_2 PF18121.1 OAJ21534.1 - 5.3e-11 42.1 0.1 1.4e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OAJ21534.1 - 7.3e-11 42.2 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain PIP5K PF01504.18 OAJ21574.1 - 7.9e-38 130.2 0.0 2.1e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase GRDP-like PF07173.12 OAJ21575.1 - 7.5e-15 55.8 1.3 4.6e-12 46.8 0.1 3.8 3 1 1 4 4 4 1 Glycine-rich domain-containing protein-like DUF4301 PF14134.6 OAJ21575.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) FSA_C PF10479.9 OAJ21576.1 - 0.57 8.3 1.4 0.78 7.8 1.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CDC50 PF03381.15 OAJ21577.1 - 1.3e-68 231.6 0.0 1.7e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ACOX PF01756.19 OAJ21578.1 - 2.8e-32 111.7 0.0 5.4e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAJ21578.1 - 1e-18 68.1 0.0 2.2e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAJ21578.1 - 1.5e-07 31.5 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ21578.1 - 3.6e-07 30.5 0.0 1.3e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Sec7 PF01369.20 OAJ21579.1 - 1.2e-65 220.6 0.0 2.1e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAJ21579.1 - 1.2e-10 41.5 0.0 3.8e-07 30.1 0.0 3.6 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF5067 PF16729.5 OAJ21579.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) F-box-like PF12937.7 OAJ21580.1 - 0.0079 16.1 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like GWT1 PF06423.12 OAJ21581.1 - 2.3e-34 118.7 0.0 6e-22 78.4 0.0 2.9 2 0 0 2 2 2 2 GWT1 DUF4818 PF16089.5 OAJ21581.1 - 0.82 10.2 4.6 0.25 11.8 0.1 2.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4818) UDPGT PF00201.18 OAJ21582.1 - 2e-13 50.0 0.0 3.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PolyA_pol PF01743.20 OAJ21583.1 - 3.1e-23 82.6 0.0 5.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAJ21583.1 - 0.0019 17.9 0.1 0.0043 16.8 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A ABC_tran PF00005.27 OAJ21631.1 - 1.4e-44 151.9 0.0 1.4e-29 103.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ21631.1 - 2.1e-29 103.0 17.2 1.6e-28 100.2 7.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ21631.1 - 2.8e-10 40.0 1.9 0.00032 20.2 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ21631.1 - 3.7e-07 30.8 0.3 0.025 15.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAJ21631.1 - 8.8e-07 28.6 0.3 0.063 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ21631.1 - 1.4e-05 25.3 1.1 0.0048 17.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ21631.1 - 1.8e-05 25.2 0.4 0.054 13.9 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAJ21631.1 - 4.1e-05 23.5 0.0 0.069 12.9 0.0 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OAJ21631.1 - 0.00091 18.4 0.0 0.2 10.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 OAJ21631.1 - 0.0013 18.5 0.1 1.4 8.6 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ21631.1 - 0.0015 18.6 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 OAJ21631.1 - 0.0025 16.7 0.1 1.1 8.0 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF87 PF01935.17 OAJ21631.1 - 0.0025 17.9 0.3 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 OAJ21631.1 - 0.0036 17.2 0.2 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OAJ21631.1 - 0.0042 17.2 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ21631.1 - 0.0064 15.9 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 OAJ21631.1 - 0.016 15.3 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 OAJ21631.1 - 0.021 14.5 1.3 0.063 13.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAJ21631.1 - 0.046 14.3 0.1 4.7 7.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 OAJ21631.1 - 0.069 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 OAJ21631.1 - 0.069 13.0 0.1 6.4 6.6 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OAJ21631.1 - 0.083 12.9 0.0 9.6 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 OAJ21631.1 - 0.26 10.9 0.9 6.5 6.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF5345 PF17280.2 OAJ21631.1 - 2.6 8.1 11.0 0.93 9.5 5.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) AAA_25 PF13481.6 OAJ21631.1 - 3.2 7.3 6.2 31 4.1 1.4 3.3 2 2 0 2 2 2 0 AAA domain HIG_1_N PF04588.13 OAJ21632.1 - 1.1e-16 60.8 0.2 1.6e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3446 PF11928.8 OAJ21632.1 - 3.3 8.1 13.7 3.6 8.0 1.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain TPR_MLP1_2 PF07926.12 OAJ21633.1 - 2.3 8.3 14.2 0.024 14.7 4.5 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Metallopep PF12044.8 OAJ21634.1 - 5.7e-85 285.5 0.0 1.8e-68 231.1 0.0 3.0 2 1 0 2 2 2 2 Putative peptidase family Jacalin PF01419.17 OAJ21634.1 - 1.8e-17 63.5 0.0 0.00047 20.1 0.0 5.0 5 0 0 5 5 5 4 Jacalin-like lectin domain Peptidase_M66 PF10462.9 OAJ21634.1 - 0.0029 16.6 0.1 0.0049 15.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 PCNA_N PF00705.18 OAJ21635.1 - 2.4e-50 169.5 2.6 7.9e-50 167.8 1.1 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OAJ21635.1 - 4.3e-43 146.5 0.0 1.4e-22 80.2 0.2 2.5 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 OAJ21635.1 - 5.4e-07 29.0 0.3 2.1e-05 23.7 0.3 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OAJ21635.1 - 0.00013 21.5 0.0 0.00044 19.8 0.0 1.8 1 1 0 1 1 1 1 Rad9 DUF3246 PF11596.8 OAJ21635.1 - 0.058 12.8 1.1 0.1 12.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FmiP_Thoc5 PF09766.9 OAJ21635.1 - 0.066 12.5 0.1 0.097 11.9 0.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 LRS4 PF10422.9 OAJ21635.1 - 0.32 10.5 3.7 0.73 9.4 1.0 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 ABC_membrane PF00664.23 OAJ21636.1 - 3.9e-06 26.7 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region PRD1_DD PF11087.8 OAJ21636.1 - 0.57 9.9 4.3 0.15 11.8 0.4 2.1 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery SAP130_C PF16014.5 OAJ21638.1 - 3 6.8 9.7 3.9 6.5 9.7 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Abhydrolase_6 PF12697.7 OAJ21639.1 - 5.1e-18 66.5 0.8 5.9e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ21639.1 - 1.3e-13 51.2 0.1 4.4e-12 46.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ21639.1 - 3.4e-13 49.4 0.1 5.4e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAJ21639.1 - 8.8e-08 32.1 0.0 2.7e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OAJ21639.1 - 0.0019 18.4 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.16 OAJ21639.1 - 0.0026 17.3 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Chlorophyllase PF07224.11 OAJ21639.1 - 0.0032 16.5 0.0 0.0046 16.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Palm_thioest PF02089.15 OAJ21639.1 - 0.0087 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 OAJ21639.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 OAJ21639.1 - 0.023 14.3 0.0 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 OAJ21639.1 - 0.06 12.2 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAJ21639.1 - 0.075 11.5 0.0 3.4 6.1 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.15 OAJ21639.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.8 OAJ21639.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Peptidase_S9 PF00326.21 OAJ21639.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family RsgA_GTPase PF03193.16 OAJ21639.1 - 0.22 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Hamartin PF04388.12 OAJ21640.1 - 4.8 5.7 6.3 6 5.4 6.3 1.1 1 0 0 1 1 1 0 Hamartin protein zf-RING_2 PF13639.6 OAJ21642.1 - 2.5e-07 30.9 1.5 9.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ21642.1 - 2.7e-07 30.5 0.3 2.7e-07 30.5 0.3 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OAJ21642.1 - 1.9e-06 27.5 2.1 4e-06 26.5 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAJ21642.1 - 3.2e-06 27.0 1.3 1.3e-05 25.1 0.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ21642.1 - 9.3e-05 22.2 0.1 9.3e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ21642.1 - 0.0019 18.0 0.4 0.0019 18.0 0.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ21642.1 - 0.014 15.7 2.7 0.015 15.6 0.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF4407 PF14362.6 OAJ21642.1 - 1.7 7.9 20.0 3.3 7.0 20.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JHY PF15261.6 OAJ21642.1 - 2.8 8.7 25.8 2.4 8.9 6.9 2.8 2 0 0 2 2 2 0 Jhy protein Prok-RING_4 PF14447.6 OAJ21642.1 - 4.7 7.2 6.6 1.5 8.7 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF87 PF01935.17 OAJ21642.1 - 9.2 6.3 8.0 18 5.3 8.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain zf-C3HC4_3 PF13920.6 OAJ21642.1 - 9.3 6.2 7.1 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 OAJ21643.1 - 7.8e-35 118.3 28.0 2.1e-06 28.3 0.5 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21643.1 - 2.9e-14 53.1 1.1 0.0039 17.5 0.0 6.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 OAJ21643.1 - 4.3e-10 39.3 0.2 9.4e-10 38.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 OAJ21643.1 - 1.1e-07 30.9 7.0 3.3 6.3 0.1 6.0 5 1 1 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 OAJ21643.1 - 4.9e-07 29.4 0.1 0.00038 19.9 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 OAJ21643.1 - 0.00029 20.5 0.8 0.043 13.4 0.1 3.3 2 1 0 2 2 2 1 PQQ-like domain F-box PF00646.33 OAJ21643.1 - 0.00037 20.3 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 OAJ21643.1 - 0.00065 20.1 5.5 6.6 7.4 0.2 5.8 5 1 0 6 6 6 2 PQQ-like domain DUF5046 PF16465.5 OAJ21643.1 - 0.034 13.6 0.0 1.3 8.4 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5046) PGAP1 PF07819.13 OAJ21644.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 OAJ21644.1 - 0.21 10.3 0.0 0.56 8.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family Transposase_21 PF02992.14 OAJ21691.1 - 0.082 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Transposase family tnp2 FCP1_C PF09309.10 OAJ21692.1 - 0.0066 16.4 7.9 0.0066 16.4 7.9 1.6 2 0 0 2 2 2 1 FCP1, C-terminal Nop53 PF07767.11 OAJ21692.1 - 0.011 15.1 22.7 0.0085 15.5 20.9 1.6 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 OAJ21692.1 - 0.15 10.3 9.1 0.17 10.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 OAJ21692.1 - 0.33 10.5 18.2 2 8.0 13.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein XAP5 PF04921.14 OAJ21692.1 - 0.36 10.6 8.2 0.61 9.9 8.2 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF1943 PF09172.11 OAJ21692.1 - 0.67 9.1 2.6 0.93 8.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) RR_TM4-6 PF06459.12 OAJ21692.1 - 0.78 9.5 8.1 1.2 8.9 8.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Aa_trans PF01490.18 OAJ21693.1 - 2.2e-30 105.7 31.7 2.6e-30 105.5 31.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 OAJ21695.1 - 3.1e-15 56.2 0.0 4.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21695.1 - 4.9e-07 29.3 0.0 6.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MULE PF10551.9 OAJ21697.1 - 1.8e-22 79.5 0.1 1.4e-21 76.7 0.0 2.4 3 0 0 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 OAJ21697.1 - 8.7e-06 24.8 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Fis1_TPR_N PF14852.6 OAJ21697.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Pex14_N PF04695.13 OAJ21698.1 - 0.0084 16.8 27.8 0.0084 16.8 27.8 4.0 4 0 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 OAJ21698.1 - 0.65 9.8 19.7 1.7 8.4 19.7 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM10 PF12519.8 OAJ21698.1 - 3.4 6.4 13.5 6.1 5.6 13.5 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 OAJ21698.1 - 7.7 3.5 19.5 12 2.9 19.5 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM76 PF16046.5 OAJ21698.1 - 9.8 5.4 28.4 17 4.6 28.4 1.3 1 0 0 1 1 1 0 FAM76 protein DEAD PF00270.29 OAJ21699.1 - 6.2e-43 146.6 0.4 9.2e-43 146.0 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ21699.1 - 1.3e-27 96.3 0.6 7.9e-27 93.8 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OAJ21699.1 - 0.00059 19.3 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 OAJ21699.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ21699.1 - 0.09 13.1 0.4 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 AAA domain End3 PF12761.7 OAJ21699.1 - 0.11 12.7 0.1 1.9 8.6 0.2 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TPR_2 PF07719.17 OAJ21700.1 - 9.5e-05 22.2 12.5 4.6 7.6 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ21700.1 - 0.0027 17.5 17.5 4 7.4 0.0 6.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ21700.1 - 0.0031 17.2 0.9 5.1 7.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ21700.1 - 0.094 13.0 3.6 8.4 6.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 OAJ21700.1 - 0.17 11.2 0.9 0.37 10.2 0.2 1.9 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 OAJ21700.1 - 0.57 10.9 5.6 7.5 7.4 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21700.1 - 2 9.2 9.9 8.3 7.2 0.3 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ21700.1 - 2.7 8.6 12.9 62 4.2 0.1 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat SH3_1 PF00018.28 OAJ21702.1 - 4.5e-13 48.6 0.1 7.2e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ21702.1 - 7.6e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ21702.1 - 2.2e-07 30.4 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OAJ21702.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SusE PF14292.6 OAJ21702.1 - 0.023 14.9 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 SusE outer membrane protein SH3_3 PF08239.11 OAJ21702.1 - 0.033 14.5 0.2 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain DUF4750 PF15938.5 OAJ21703.1 - 0.012 15.2 0.9 0.012 15.2 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4750) TrbC PF04956.13 OAJ21703.1 - 3.1 8.1 14.9 0.5 10.6 0.2 4.4 4 0 0 4 4 4 0 TrbC/VIRB2 family CLP1_P PF16575.5 OAJ21704.1 - 1.5e-24 86.9 0.0 4.7e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 OAJ21704.1 - 0.025 15.0 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 OAJ21704.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 OAJ21704.1 - 0.14 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 OAJ21704.1 - 0.22 11.6 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain WW PF00397.26 OAJ21753.1 - 3.7e-08 33.3 0.6 5.7e-08 32.7 0.6 1.3 1 0 0 1 1 1 1 WW domain Peptidase_M16 PF00675.20 OAJ21754.1 - 1.9e-15 57.1 0.0 4.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ21754.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Robl_LC7 PF03259.17 OAJ21754.1 - 3.2 7.6 5.1 0.9 9.4 0.2 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain PhoLip_ATPase_C PF16212.5 OAJ21755.1 - 6.1e-71 239.1 25.4 6.1e-71 239.1 25.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ21755.1 - 4.9e-20 71.0 3.3 4.9e-20 71.0 3.3 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAJ21755.1 - 1.4e-12 47.5 0.0 6.9e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ21755.1 - 2.9e-10 40.8 1.2 1.9e-05 25.1 0.5 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ21755.1 - 1e-06 28.4 0.7 5.2e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ21755.1 - 0.00059 19.6 0.7 0.0087 15.8 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 OAJ21756.1 - 0.0011 19.8 0.0 0.58 11.1 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Sugar_tr PF00083.24 OAJ21757.1 - 8.6e-44 150.1 22.8 3e-42 145.1 22.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ21757.1 - 5.9e-16 58.3 36.0 7e-08 31.8 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ21757.1 - 0.00024 19.6 1.8 0.011 14.0 0.0 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Acyltransferase PF01553.21 OAJ21759.1 - 2.8e-10 39.9 0.0 0.00017 21.2 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase RNA_pol_3_Rpc31 PF11705.8 OAJ21759.1 - 0.47 10.7 11.9 0.41 10.9 9.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAJ21759.1 - 4.8 5.3 5.7 8.7 4.4 5.7 1.3 1 0 0 1 1 1 0 Nop14-like family DDE_1 PF03184.19 OAJ21760.1 - 1.2e-18 67.4 0.0 2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ21760.1 - 1.4e-09 37.8 0.1 6.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TMEM191C PF15194.6 OAJ21760.1 - 0.03 14.5 0.5 0.08 13.1 0.5 1.7 1 0 0 1 1 1 0 TMEM191C family DUF5338 PF17273.2 OAJ21760.1 - 8.8 6.5 7.1 0.42 10.7 0.4 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5338) VHS PF00790.19 OAJ21761.1 - 1.2e-19 70.6 0.0 2.6e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAJ21761.1 - 2.7e-06 27.6 0.9 7.6e-06 26.1 0.7 1.9 2 0 0 2 2 2 1 GAT domain mRNA_stabil PF13929.6 OAJ21761.1 - 0.047 12.7 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 mRNA stabilisation DUF572 PF04502.13 OAJ21761.1 - 0.85 9.2 12.2 0.11 12.1 8.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) CCDC50_N PF15295.6 OAJ21761.1 - 2.1 8.5 15.7 0.084 13.0 9.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus AAA_11 PF13086.6 OAJ21761.1 - 2.8 7.6 9.9 2.5 7.8 8.8 1.6 1 1 0 1 1 1 0 AAA domain Tfb4 PF03850.14 OAJ21761.1 - 9.5 5.6 8.1 4.2 6.8 4.4 2.0 2 0 0 2 2 2 0 Transcription factor Tfb4 ATG11 PF10377.9 OAJ21762.1 - 5.5e-27 94.4 0.0 1.7e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 11 GIT_CC PF16559.5 OAJ21762.1 - 0.16 11.8 0.3 13 5.8 0.1 3.0 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_PEP_C PF04513.12 OAJ21762.1 - 7.9 6.5 18.6 1.2 9.2 0.3 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Histone PF00125.24 OAJ21812.1 - 7.5e-35 120.2 0.0 9e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ21812.1 - 4.1e-05 23.7 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ21812.1 - 0.047 14.1 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein CDC45 PF02724.14 OAJ21813.1 - 0.024 12.9 0.7 0.041 12.2 0.7 1.3 1 0 0 1 1 1 0 CDC45-like protein 3Beta_HSD PF01073.19 OAJ21814.1 - 9.7e-19 67.4 0.0 6e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ21814.1 - 3e-16 59.6 0.1 6.2e-16 58.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ21814.1 - 1.4e-12 47.9 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAJ21814.1 - 4.6e-11 42.4 0.0 1.3e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ21814.1 - 3.1e-08 33.4 0.0 1.7e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAJ21814.1 - 5.1e-08 32.8 0.0 7.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OAJ21814.1 - 3.4e-05 23.1 0.1 5.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAJ21814.1 - 0.00014 21.3 0.8 0.014 14.9 0.1 2.6 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ21814.1 - 0.0064 16.8 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAJ21814.1 - 0.0093 16.1 0.0 0.038 14.2 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 OAJ21814.1 - 0.048 12.8 0.1 0.089 11.9 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 OAJ21814.1 - 0.078 12.9 0.3 1.8 8.4 0.3 2.2 1 1 0 1 1 1 0 KR domain Transposase_21 PF02992.14 OAJ21815.1 - 2.6e-07 30.1 0.0 4.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ21815.1 - 1.6e-06 27.7 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PBP1_TM PF14812.6 OAJ21815.1 - 0.00025 21.4 3.8 0.0019 18.6 2.8 2.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1258 PF06869.12 OAJ21815.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Plavaka PF18759.1 OAJ21815.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Plavaka transposase TLP-20 PF06088.11 OAJ21815.1 - 0.27 11.1 1.3 0.59 10.0 1.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pns11_12 PF17464.2 OAJ21815.1 - 0.82 9.3 6.1 1.7 8.3 6.1 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Spt20 PF12090.8 OAJ21817.1 - 1.4 8.5 5.9 4.2 6.9 5.9 1.8 1 0 0 1 1 1 0 Spt20 family Ribosomal_S8 PF00410.19 OAJ21818.1 - 7.2e-12 45.4 0.0 7.2e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 vATP-synt_AC39 PF01992.16 OAJ21819.1 - 3.3e-108 362.2 0.0 3.7e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SRP40_C PF05022.12 OAJ21821.1 - 1e-28 100.0 5.7 4.7e-28 97.8 5.7 2.3 1 0 0 1 1 1 1 SRP40, C-terminal domain Asp PF00026.23 OAJ21823.1 - 1.5e-72 244.7 0.2 2.2e-72 244.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21823.1 - 1.7e-11 44.7 0.2 9.9e-09 35.7 0.2 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal KdgM PF06178.13 OAJ21823.1 - 0.22 11.1 0.1 0.45 10.1 0.0 1.5 2 0 0 2 2 2 0 Oligogalacturonate-specific porin protein (KdgM) Hfq PF17209.3 OAJ21824.1 - 0.23 11.1 0.0 0.47 10.1 0.0 1.5 1 0 0 1 1 1 0 Hfq protein Lum_binding PF00677.17 OAJ21825.1 - 1.8e-36 124.0 0.0 4.3e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain GDP_Man_Dehyd PF16363.5 OAJ21826.1 - 8.8e-47 160.1 0.0 7.3e-42 143.9 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ21826.1 - 9.2e-45 153.0 0.0 1.8e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ21826.1 - 7.2e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ21826.1 - 4.1e-08 32.7 0.0 0.00031 20.0 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAJ21826.1 - 7.2e-08 31.9 0.0 2.3e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAJ21826.1 - 2.1e-05 23.8 0.0 0.062 12.4 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein DUF410 PF04190.13 OAJ21827.1 - 2.3e-58 198.0 0.0 3e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Sld5 PF05916.11 OAJ21828.1 - 7.8e-06 26.3 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein PRP1_N PF06424.12 OAJ21829.1 - 4.2e-47 160.3 3.7 1.2e-46 158.8 3.7 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OAJ21829.1 - 1.3e-26 91.0 27.8 0.011 16.5 0.0 13.9 6 5 8 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ21829.1 - 6.3e-22 77.9 6.9 0.00087 19.8 0.0 8.1 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21829.1 - 2.8e-09 37.4 14.9 0.0068 17.0 1.2 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ21829.1 - 1.4e-08 34.2 0.4 12 6.3 0.0 8.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ21829.1 - 2.6e-07 30.7 1.7 0.035 14.3 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ21829.1 - 2.1e-05 24.5 0.2 2.9 8.5 0.0 5.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ21829.1 - 0.00036 21.0 1.7 14 6.6 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ21829.1 - 0.00088 19.3 0.4 55 4.3 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat FAT PF02259.23 OAJ21829.1 - 0.0011 18.3 13.1 0.013 14.7 2.2 4.1 2 1 1 3 3 3 2 FAT domain Suf PF05843.14 OAJ21829.1 - 0.017 15.1 0.6 3.1 7.7 0.0 4.4 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 OAJ21829.1 - 0.16 10.9 7.4 2.3 7.0 0.1 4.5 4 1 2 6 6 6 0 NMDA receptor-regulated protein 1 zf-DNL PF05180.12 OAJ21830.1 - 4.4e-30 103.4 0.0 6.6e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 OAJ21830.1 - 1.2 9.1 3.7 8.3 6.4 0.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Cyclin PF08613.11 OAJ21892.1 - 2.5e-08 34.5 0.2 6.4e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Cyclin Syntaxin-6_N PF09177.11 OAJ21893.1 - 2.1e-16 60.3 1.0 2.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4407 PF14362.6 OAJ21893.1 - 0.00028 20.4 0.0 0.00049 19.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) FliJ PF02050.16 OAJ21893.1 - 0.00034 20.8 2.7 0.0086 16.3 0.5 2.5 2 1 1 3 3 3 1 Flagellar FliJ protein DUF2046 PF09755.9 OAJ21893.1 - 0.00081 18.7 2.4 0.38 9.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Use1 PF09753.9 OAJ21893.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 HisKA_3 PF07730.13 OAJ21893.1 - 0.011 16.2 4.1 0.47 11.0 0.1 2.4 2 0 0 2 2 2 0 Histidine kinase FlaC_arch PF05377.11 OAJ21893.1 - 0.022 15.2 0.3 12 6.4 0.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ARTD15_N PF18084.1 OAJ21893.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ARTD15 N-terminal domain SNARE PF05739.19 OAJ21893.1 - 0.11 12.5 8.1 0.054 13.5 4.5 2.3 2 1 0 2 2 2 0 SNARE domain DUF1664 PF07889.12 OAJ21893.1 - 0.14 12.2 0.3 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 OAJ21893.1 - 0.3 11.6 1.2 5.5 7.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 ZapB PF06005.12 OAJ21893.1 - 1.6 9.3 7.5 1.7 9.2 0.3 3.0 3 1 1 4 4 4 0 Cell division protein ZapB ATG16 PF08614.11 OAJ21893.1 - 3.8 7.7 8.9 24 5.1 0.1 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OAJ21893.1 - 5.1 7.2 8.8 8.6 6.4 2.6 3.0 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein G10 PF01125.17 OAJ21894.1 - 4.6e-56 188.7 7.6 8.4e-56 187.8 7.6 1.4 1 0 0 1 1 1 1 G10 protein DHQ_synthase PF01761.20 OAJ21894.1 - 0.00052 19.3 0.0 0.00095 18.4 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase Phage_integrase PF00589.22 OAJ21898.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUF596 PF04591.12 OAJ21898.1 - 0.028 14.6 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF596 AMP-binding PF00501.28 OAJ21899.1 - 3.4e-70 236.8 0.0 4.3e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ21899.1 - 0.00081 20.3 0.2 0.0023 18.9 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ig_Tie2_1 PF10430.9 OAJ21899.1 - 0.065 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 EF_assoc_2 PF08356.12 OAJ21900.1 - 6.5e-24 83.7 0.0 4.6e-23 81.0 0.0 2.3 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 OAJ21900.1 - 1.7e-20 72.4 2.2 2.4e-20 71.9 0.5 2.1 2 1 0 2 2 1 1 EF hand associated Ras PF00071.22 OAJ21900.1 - 5.5e-16 58.6 0.0 0.00032 20.3 0.0 4.9 5 0 0 5 5 5 3 Ras family Roc PF08477.13 OAJ21900.1 - 2.2e-07 31.1 0.0 0.003 17.8 0.0 4.4 5 0 0 5 5 4 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ21900.1 - 1e-06 28.8 0.0 0.00047 20.2 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 OAJ21900.1 - 3.3e-06 27.4 0.4 0.046 14.2 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.6 OAJ21900.1 - 9.5e-06 25.9 0.0 0.26 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OAJ21900.1 - 2.1e-05 24.5 0.6 0.0047 16.9 0.0 3.7 4 0 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 OAJ21900.1 - 3.3e-05 24.4 0.5 0.052 13.9 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain ABC_tran PF00005.27 OAJ21900.1 - 5.4e-05 23.7 0.1 0.037 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter EF-hand_6 PF13405.6 OAJ21900.1 - 9.2e-05 22.1 4.9 0.063 13.2 0.2 3.0 3 0 0 3 3 2 2 EF-hand domain Dynamin_N PF00350.23 OAJ21900.1 - 0.00037 20.6 0.1 0.98 9.5 0.1 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 OAJ21900.1 - 0.00043 20.0 0.1 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AIG1 PF04548.16 OAJ21900.1 - 0.00059 19.2 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family NACHT PF05729.12 OAJ21900.1 - 0.0024 17.8 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 OAJ21900.1 - 0.0055 17.2 0.1 0.32 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ21900.1 - 0.0095 16.1 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ21900.1 - 0.013 15.9 0.1 0.83 10.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ21900.1 - 0.017 14.3 0.2 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 OAJ21900.1 - 0.025 13.9 0.0 0.088 12.1 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 OAJ21900.1 - 0.03 14.6 0.1 8.6 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ21900.1 - 0.031 13.8 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OAJ21900.1 - 0.032 13.9 0.3 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ21900.1 - 0.037 13.8 0.0 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ21900.1 - 0.056 13.8 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase EF-hand_1 PF00036.32 OAJ21900.1 - 0.058 13.0 12.4 0.21 11.2 0.1 3.4 4 0 0 4 4 3 0 EF hand Viral_helicase1 PF01443.18 OAJ21900.1 - 0.078 12.7 0.0 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 OAJ21900.1 - 0.081 12.4 0.1 0.081 12.4 0.1 3.2 4 0 0 4 4 3 0 EF hand cobW PF02492.19 OAJ21900.1 - 0.12 11.9 0.2 11 5.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 OAJ21900.1 - 0.16 11.1 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 OAJ21900.1 - 0.2 12.2 0.2 16 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OAJ21900.1 - 0.23 11.3 0.0 1.5 8.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 OAJ21900.1 - 0.24 11.1 0.3 37 4.0 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Ras PF00071.22 OAJ21901.1 - 4e-62 208.6 0.1 4.7e-62 208.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ21901.1 - 1.1e-33 116.0 0.0 1.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ21901.1 - 2.5e-12 46.6 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ21901.1 - 5.7e-06 26.4 0.0 9.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ21901.1 - 0.00016 21.3 0.1 0.00086 18.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ21901.1 - 0.0012 18.8 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAJ21901.1 - 0.0037 17.6 0.1 0.052 13.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAJ21901.1 - 0.0039 17.6 0.1 0.0066 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OAJ21901.1 - 0.0055 16.1 0.0 0.0076 15.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ21901.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAJ21901.1 - 0.025 14.3 0.0 0.079 12.7 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OAJ21901.1 - 0.043 14.3 0.1 0.072 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 OAJ21901.1 - 0.043 14.1 0.2 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ21901.1 - 0.052 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ21901.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAJ21901.1 - 0.084 12.3 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 OAJ21901.1 - 0.086 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 OAJ21901.1 - 0.087 12.6 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OAJ21901.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AEP1 PF17049.5 OAJ21901.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 DUF2420 PF10336.9 OAJ21902.1 - 4.6e-05 23.4 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) RCC1 PF00415.18 OAJ21903.1 - 1.2e-14 54.6 5.2 0.011 16.3 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAJ21903.1 - 1.5e-10 41.2 0.0 3.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 OAJ21903.1 - 1.2e-08 35.1 0.3 2.2e-06 27.8 0.2 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ21903.1 - 2.3e-07 31.2 0.4 8.4e-05 23.1 0.4 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 OAJ21903.1 - 5.1e-06 26.1 14.5 0.0017 18.1 0.0 6.3 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 OAJ21903.1 - 5.6e-06 26.9 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ21903.1 - 5.9e-05 23.2 1.1 0.39 11.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OAJ21903.1 - 0.0063 16.9 3.9 0.29 11.7 0.3 3.4 3 0 0 3 3 3 1 Ankyrin repeat THF_DHG_CYH PF00763.23 OAJ21904.1 - 1.1e-22 80.5 0.0 2.3e-22 79.4 0.0 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAJ21904.1 - 2e-13 50.0 0.1 6.1e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 OAJ21904.1 - 0.086 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family MFAP1 PF06991.11 OAJ21905.1 - 1.6e-63 214.4 20.8 1.6e-63 214.4 20.8 2.4 3 0 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 OAJ21905.1 - 0.12 12.5 1.0 0.28 11.3 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Rep_fac-A_C PF08646.10 OAJ21957.1 - 3.1e-56 189.2 2.1 3.2e-55 185.9 1.0 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAJ21957.1 - 1.5e-35 121.0 0.3 4.4e-35 119.5 0.3 1.8 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 OAJ21957.1 - 3e-24 84.9 0.0 6.9e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAJ21957.1 - 6.3e-13 48.5 0.4 1.1e-10 41.3 0.0 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 OAJ21957.1 - 0.00013 22.2 0.2 0.0069 16.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 OAJ21957.1 - 0.013 15.3 0.1 0.67 9.6 0.0 2.7 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 F-box-like PF12937.7 OAJ21958.1 - 0.0023 17.8 0.8 0.006 16.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like CHASE2 PF05226.11 OAJ21958.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain AMP-binding PF00501.28 OAJ21959.1 - 1.1e-211 702.9 0.0 4.5e-74 249.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 OAJ21959.1 - 4.1e-106 355.4 0.0 8.3e-32 110.4 0.0 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 OAJ21959.1 - 7.1e-38 128.8 2.9 5.8e-09 36.2 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ21959.1 - 1.5e-05 25.9 0.1 3 8.9 0.0 4.5 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 OAJ21959.1 - 0.0046 15.7 0.0 0.43 9.2 0.0 3.1 3 0 0 3 3 3 1 Transferase family WES_acyltransf PF03007.16 OAJ21959.1 - 0.042 13.6 0.1 6.7 6.4 0.1 2.9 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Peptidase_M50B PF13398.6 OAJ21960.1 - 4.8e-56 189.6 15.1 6e-56 189.2 15.1 1.0 1 0 0 1 1 1 1 Peptidase M50B-like HATPase_c PF02518.26 OAJ21961.1 - 5.8e-29 100.9 0.0 1.4e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ21961.1 - 5.1e-25 87.8 0.0 3.6e-24 85.1 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAJ21961.1 - 1.7e-19 69.6 0.1 4.9e-19 68.1 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAJ21961.1 - 6.9e-19 67.9 1.2 1.3e-18 67.1 0.4 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAJ21961.1 - 2.6e-16 59.8 1.0 2.5e-07 30.9 0.0 4.8 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 OAJ21961.1 - 6e-11 42.3 0.0 0.013 15.5 0.0 4.6 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 OAJ21961.1 - 6.1e-08 32.9 0.0 1.8e-06 28.1 0.0 3.4 4 1 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.6 OAJ21961.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_31 PF13614.6 OAJ21961.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PWI PF01480.17 OAJ21962.1 - 7.5e-26 90.3 0.0 1.1e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.25 OAJ21963.1 - 6.8e-63 212.5 0.0 9.4e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21963.1 - 9.7e-28 97.1 0.0 4.9e-27 94.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ21963.1 - 1.8e-05 25.3 2.5 5.2e-05 23.9 0.7 2.8 2 1 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OAJ21963.1 - 0.0023 16.8 0.0 0.0075 15.1 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OAJ21963.1 - 0.0062 16.2 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAJ21963.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ21963.1 - 0.11 12.4 3.9 2.3 8.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family EB PF01683.18 OAJ21964.1 - 6.3 7.2 11.6 5.2 7.5 2.9 2.2 2 0 0 2 2 2 0 EB module SOG2 PF10428.9 OAJ21965.1 - 0.24 10.5 19.9 0.24 10.5 19.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Lir1 PF07207.11 OAJ21965.1 - 1.7 8.9 9.6 1.4 9.2 8.5 1.4 1 1 0 1 1 1 0 Light regulated protein Lir1 TRAPPC9-Trs120 PF08626.11 OAJ21965.1 - 1.9 5.7 7.9 1.8 5.8 7.9 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit PAP1 PF08601.10 OAJ21965.1 - 3.6 7.2 22.3 3.9 7.1 22.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 QWRF PF04484.12 OAJ21965.1 - 5.2 6.7 13.7 5.4 6.7 13.7 1.0 1 0 0 1 1 1 0 QWRF family Pkinase PF00069.25 OAJ22014.1 - 5.2e-32 111.3 0.0 1.3e-31 109.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22014.1 - 6.1e-09 35.5 0.0 1.7e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase FAM76 PF16046.5 OAJ22015.1 - 0.0051 16.2 0.3 0.0068 15.8 0.3 1.1 1 0 0 1 1 1 1 FAM76 protein CtIP_N PF10482.9 OAJ22015.1 - 0.051 13.6 1.6 0.084 12.9 1.6 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 OAJ22015.1 - 0.061 13.8 4.0 0.12 12.9 4.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Spond_N PF06468.13 OAJ22015.1 - 0.12 12.5 1.5 0.17 12.0 0.4 1.7 2 0 0 2 2 2 0 Spondin_N DUF3450 PF11932.8 OAJ22015.1 - 0.83 8.9 7.2 1.2 8.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BST2 PF16716.5 OAJ22015.1 - 1.1 9.9 5.6 1.7 9.3 5.6 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DivIC PF04977.15 OAJ22015.1 - 2.9 7.7 5.5 5.2 6.9 5.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Pro_isomerase PF00160.21 OAJ22016.1 - 3.4e-45 154.2 0.1 6.4e-45 153.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Xpo1 PF08389.12 OAJ22016.1 - 8e-15 55.2 0.0 7.6e-14 52.0 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 OAJ22016.1 - 0.00088 19.6 0.3 0.0047 17.3 0.3 2.3 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OAJ22016.1 - 0.024 14.9 0.1 0.4 11.1 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 OAJ22016.1 - 0.12 12.4 0.1 0.71 10.0 0.1 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3295 PF11702.8 OAJ22017.1 - 7e-12 45.5 1.9 7e-12 45.5 1.9 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3295) SDA1 PF05285.12 OAJ22017.1 - 4 6.8 16.7 6.7 6.0 16.5 1.4 1 1 0 1 1 1 0 SDA1 EPL1 PF10513.9 OAJ22018.1 - 1e-18 68.2 0.0 1e-18 68.2 0.0 5.0 4 1 0 4 4 4 2 Enhancer of polycomb-like Glyco_hydro_16 PF00722.21 OAJ22019.1 - 4.4e-05 23.0 0.1 9.5e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 ISG65-75 PF11727.8 OAJ22020.1 - 0.0061 15.8 6.7 0.0098 15.2 6.7 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein MarC PF01914.17 OAJ22020.1 - 0.44 9.9 0.8 0.98 8.8 0.8 1.5 1 0 0 1 1 1 0 MarC family integral membrane protein NARP1 PF12569.8 OAJ22020.1 - 3.9 6.3 13.3 6.8 5.5 13.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peroxidase_2 PF01328.17 OAJ22021.1 - 1.2e-42 146.6 0.0 1.6e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Solute_trans_a PF03619.16 OAJ22022.1 - 8.4e-85 284.5 25.2 1e-84 284.2 25.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 OAJ22022.1 - 0.005 17.0 2.1 0.005 17.0 2.1 2.1 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_3 PF07859.13 OAJ22023.1 - 1.5e-33 116.4 0.0 2.1e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ22023.1 - 0.00014 21.4 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ22023.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAJ22023.1 - 0.0026 18.4 0.7 0.0051 17.4 0.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OAJ22023.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) BAAT_C PF08840.11 OAJ22023.1 - 0.004 17.1 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAJ22023.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAJ22023.1 - 0.024 13.9 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 HECT_2 PF09814.9 OAJ22024.1 - 1.8e-32 112.6 0.0 2.2e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Mannosyl_trans3 PF11051.8 OAJ22067.1 - 3.4e-05 23.3 0.0 0.00044 19.7 0.0 2.4 2 1 0 2 2 2 1 Mannosyltransferase putative XAP5 PF04921.14 OAJ22068.1 - 4.7e-89 298.5 7.6 4.7e-89 298.5 7.6 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator Mucin PF01456.17 OAJ22068.1 - 0.2 11.6 10.2 0.3 11.1 10.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S64 PF08192.11 OAJ22068.1 - 2.5 6.5 9.9 2.9 6.3 9.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 MOZART1 PF12554.8 OAJ22069.1 - 1.4e-15 56.7 0.1 1.7e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SelB-wing_2 PF09106.11 OAJ22069.1 - 0.055 13.7 0.2 0.15 12.3 0.0 1.7 1 1 1 2 2 2 0 Elongation factor SelB, winged helix UPF0181 PF03701.14 OAJ22069.1 - 0.091 12.4 0.2 0.22 11.2 0.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0181) Ribul_P_3_epim PF00834.19 OAJ22070.1 - 4.9e-67 225.2 0.0 5.9e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OAJ22070.1 - 0.0016 18.2 0.0 0.006 16.4 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain BATS PF06968.13 OAJ22070.1 - 0.16 12.1 0.0 7.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain Abhydrolase_3 PF07859.13 OAJ22071.1 - 3.2e-10 40.2 0.0 4.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ22071.1 - 4.3e-09 37.3 2.3 9.5e-09 36.2 2.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ22071.1 - 5.3e-09 35.7 0.4 2e-07 30.5 0.1 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ22071.1 - 2.4e-06 27.4 0.1 4.8e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ22071.1 - 0.0089 15.5 0.1 0.072 12.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 OAJ22071.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Methyltr_RsmB-F PF01189.17 OAJ22072.1 - 8.3e-72 241.0 0.0 1.2e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAJ22072.1 - 5.5e-09 36.4 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAJ22072.1 - 0.0012 19.0 0.0 0.0078 16.3 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 OAJ22072.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 OAJ22072.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAJ22072.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 OAJ22072.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) XPG_I PF00867.18 OAJ22073.1 - 1.1e-15 57.7 0.0 8.5e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAJ22073.1 - 5e-06 26.9 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 OAJ22073.1 - 0.0048 17.8 1.7 0.0048 17.8 1.7 5.7 5 3 0 5 5 5 1 Holliday junction resolvase Gen1 C-terminal domain PP2C PF00481.21 OAJ22075.1 - 7.8e-35 120.7 0.0 2.1e-32 112.8 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C Radical_SAM_C PF16199.5 OAJ22076.1 - 2e-31 107.8 0.0 4.3e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAJ22076.1 - 9.9e-19 68.3 0.4 8.2e-18 65.3 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAJ22076.1 - 9.1e-08 32.3 0.1 2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ22076.1 - 8.1e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ22076.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.11 OAJ22077.1 - 2.2e-09 37.9 0.9 4.8e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAJ22077.1 - 3.4e-09 36.6 0.1 5.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 OAJ22077.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 HTH_20 PF12840.7 OAJ22077.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain BOF PF04076.13 OAJ22077.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein 4F5 PF04419.14 OAJ22079.1 - 2.4e-09 37.9 8.8 2.4e-09 37.9 8.8 2.2 2 0 0 2 2 2 1 4F5 protein family CdhC PF03598.15 OAJ22079.1 - 0.089 12.7 0.0 0.094 12.6 0.0 1.0 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Chs7 PF12271.8 OAJ22080.1 - 1.1e-50 172.7 10.7 1.3e-50 172.4 10.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Soyouz_module PF14313.6 OAJ22080.1 - 0.00012 21.8 0.5 0.00063 19.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of Paramyxovirinae phosphoprotein (P) PsbX PF06596.11 OAJ22080.1 - 4.9 7.2 7.8 3.1 7.9 0.2 3.4 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Syja_N PF02383.18 OAJ22081.1 - 1.1e-77 261.5 0.0 1.5e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAJ22081.1 - 3.5e-28 97.6 0.0 1.6e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase RRM_1 PF00076.22 OAJ22132.1 - 3.1e-31 107.0 0.1 3.4e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ22132.1 - 1.1e-11 44.6 0.1 7.1e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Mpt_N PF09176.11 OAJ22132.1 - 0.016 15.4 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Nup35_RRM_2 PF14605.6 OAJ22132.1 - 0.017 15.1 0.0 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAJ22132.1 - 0.095 12.8 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Sec1 PF00995.23 OAJ22133.1 - 1.5e-129 433.9 0.0 1.7e-129 433.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YxiJ PF14176.6 OAJ22133.1 - 0.014 15.9 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 YxiJ-like protein Methyltransf_16 PF10294.9 OAJ22134.1 - 7.2e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAJ22134.1 - 0.00025 20.5 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAJ22134.1 - 0.0025 18.5 0.1 0.0086 16.8 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ22134.1 - 0.052 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22134.1 - 0.069 13.8 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22134.1 - 0.12 12.2 0.0 2.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ22134.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain KDZ PF18758.1 OAJ22135.1 - 3e-53 180.7 0.0 5.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ22135.1 - 1.3e-05 25.3 0.0 2.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ22135.1 - 3.3e-05 24.0 0.0 7.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 OAJ22135.1 - 0.022 14.6 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases UPF0020 PF01170.18 OAJ22137.1 - 3.4e-08 33.4 0.1 1.9e-06 27.7 0.1 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OAJ22137.1 - 4.5e-05 23.3 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 DNA methylase N6_Mtase PF02384.16 OAJ22137.1 - 0.0054 16.0 0.0 0.018 14.3 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 OAJ22137.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 OAJ22137.1 - 0.074 13.8 0.0 0.23 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22137.1 - 0.17 12.6 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M76 PF09768.9 OAJ22138.1 - 5.8e-51 172.7 0.0 7.6e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OAJ22138.1 - 0.0023 17.8 0.0 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 SprT-like family Ferritin_2 PF13668.6 OAJ22139.1 - 7.8e-43 145.9 5.0 1.2e-42 145.4 5.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ribosomal_L1 PF00687.21 OAJ22140.1 - 6e-24 84.9 0.0 6e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family PhdYeFM_antitox PF02604.19 OAJ22140.1 - 0.056 13.3 0.2 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Lyase_1 PF00206.20 OAJ22141.1 - 8.6e-118 393.3 0.0 1.3e-117 392.7 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAJ22141.1 - 2.2e-19 69.6 0.0 6.6e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus GLTSCR1 PF15249.6 OAJ22142.1 - 8.8e-10 38.9 0.5 1.8e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein RNA_pol_Rpb2_6 PF00562.28 OAJ22143.1 - 2.8e-121 405.3 0.3 1.5e-117 393.0 0.2 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ22143.1 - 2e-62 210.3 0.1 3e-62 209.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAJ22143.1 - 2.5e-47 161.0 0.0 4.9e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ22143.1 - 1.5e-31 108.6 0.1 3.9e-31 107.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAJ22143.1 - 1e-25 89.6 0.1 3e-25 88.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OAJ22143.1 - 2.2e-23 82.3 0.4 6.1e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OAJ22143.1 - 1.3e-19 70.5 0.1 3.5e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Haspin_kinase PF12330.8 OAJ22144.1 - 5.8e-49 167.0 0.0 1.4e-48 165.7 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain DUF5343 PF17278.2 OAJ22144.1 - 0.029 14.4 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) RRN3 PF05327.11 OAJ22144.1 - 5.2 5.5 4.5 8.8 4.7 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CWC25 PF12542.8 OAJ22145.1 - 2e-25 89.7 1.0 2e-25 89.7 1.0 3.7 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAJ22145.1 - 6.3e-14 51.9 12.2 6.3e-14 51.9 12.2 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DEAD PF00270.29 OAJ22146.1 - 0.00043 20.1 0.0 0.00049 19.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.25 OAJ22147.1 - 0.00033 20.5 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Phage_integrase PF00589.22 OAJ22188.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Med26 PF08711.11 OAJ22189.1 - 1.1e-09 38.2 0.1 4.6e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain eIF-5_eIF-2B PF01873.17 OAJ22191.1 - 3.2e-39 133.4 0.1 7.1e-39 132.3 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 OAJ22191.1 - 2.3e-18 66.1 0.2 1e-17 64.0 0.1 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4611 PF15387.6 OAJ22191.1 - 2.1 8.6 8.0 21 5.4 4.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF974 PF06159.13 OAJ22192.1 - 1.8e-42 145.8 0.0 1.2e-35 123.5 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF974) Nop14 PF04147.12 OAJ22193.1 - 0.032 12.5 5.8 0.039 12.2 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pro_isomerase PF00160.21 OAJ22194.1 - 1.4e-14 54.7 0.0 1.9e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ins_beta PF03488.14 OAJ22195.1 - 0.069 13.2 0.8 0.069 13.2 0.8 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Vanabin-2 PF11437.8 OAJ22195.1 - 0.074 13.2 0.2 0.074 13.2 0.2 2.3 2 0 0 2 2 2 0 Vanadium-binding protein 2 R3H PF01424.22 OAJ22197.1 - 8.5e-11 41.7 0.2 1.9e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAJ22197.1 - 1.1e-06 28.4 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.18 OAJ22198.1 - 1.7e-20 72.7 0.0 4.5e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 NAC domain Striatin PF08232.12 OAJ22199.1 - 2.4e-46 158.2 1.9 2.4e-46 158.2 1.9 5.0 3 2 0 3 3 3 1 Striatin family WD40 PF00400.32 OAJ22199.1 - 4.1e-29 100.2 6.9 5.7e-06 27.0 0.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ22199.1 - 8.9e-05 22.7 0.0 0.41 11.0 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain adh_short_C2 PF13561.6 OAJ22200.1 - 3.4e-45 154.4 0.0 4e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ22200.1 - 1.9e-36 125.4 0.0 2.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ22200.1 - 2.5e-09 37.3 0.1 3.1e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAJ22200.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Integrase_H2C2 PF17921.1 OAJ22201.1 - 3.8e-05 23.7 0.1 3.8e-05 23.7 0.1 2.2 2 0 0 2 2 1 1 Integrase zinc binding domain Utp21 PF04192.12 OAJ22201.1 - 0.026 14.1 8.0 0.057 12.9 1.3 2.3 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Med3 PF11593.8 OAJ22201.1 - 0.1 11.8 20.2 0.13 11.5 6.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal FAM193_C PF15914.5 OAJ22201.1 - 0.24 11.2 0.4 0.48 10.2 0.4 1.4 1 0 0 1 1 1 0 FAM193 family C-terminal TFIIA PF03153.13 OAJ22201.1 - 0.28 11.2 33.5 0.28 11.1 14.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 OAJ22201.1 - 1.1 7.7 21.2 0.15 10.6 7.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 EPL1 PF10513.9 OAJ22201.1 - 1.4 9.3 11.0 1.1 9.7 3.0 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Presenilin PF01080.17 OAJ22201.1 - 1.5 7.5 6.7 11 4.6 3.3 2.2 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 OAJ22201.1 - 5.3 7.0 9.1 0.74 9.8 1.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 OAJ22201.1 - 7 6.5 15.9 0.62 10.0 5.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.6 OAJ22201.1 - 7.3 5.7 9.3 1 8.5 1.9 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DEAD PF00270.29 OAJ22203.1 - 1.7e-41 141.9 0.6 3.5e-41 140.9 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ22203.1 - 2.2e-25 89.1 0.3 9.3e-25 87.1 0.1 2.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Pyridox_ox_2 PF12900.7 OAJ22203.1 - 6.6e-06 26.2 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ResIII PF04851.15 OAJ22203.1 - 7.1e-05 22.9 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ22203.1 - 0.00013 22.3 0.4 0.0011 19.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ22203.1 - 0.0018 18.1 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 OAJ22203.1 - 0.05 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 OAJ22203.1 - 0.072 12.4 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 OAJ22203.1 - 0.074 12.6 0.1 0.096 12.2 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MARVEL PF01284.23 OAJ22256.1 - 1.8e-06 28.0 8.8 2.9e-06 27.4 8.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.14 OAJ22256.1 - 0.048 14.1 0.1 0.078 13.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) TAN PF11640.8 OAJ22257.1 - 0.042 14.0 0.1 2.8 8.1 0.0 3.0 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Mito_carr PF00153.27 OAJ22258.1 - 0.068 13.1 0.4 4.4 7.3 0.1 3.2 3 0 0 3 3 3 0 Mitochondrial carrier protein Methyltransf_23 PF13489.6 OAJ22259.1 - 1.4e-20 73.7 0.0 3.2e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22259.1 - 1.5e-16 60.8 0.3 6.9e-16 58.7 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ22259.1 - 6.4e-14 52.4 0.3 8e-12 45.7 0.3 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22259.1 - 2.6e-13 50.0 0.0 1.6e-05 24.8 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ22259.1 - 4.9e-13 49.7 0.1 3e-12 47.1 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ22259.1 - 1.2e-06 28.0 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAJ22259.1 - 7.7e-06 25.0 0.0 0.0054 15.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) PrmA PF06325.13 OAJ22259.1 - 0.0002 20.8 0.0 0.00043 19.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OAJ22259.1 - 0.001 19.1 0.1 0.0024 17.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAJ22259.1 - 0.0062 16.2 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) DREV PF05219.12 OAJ22259.1 - 0.024 13.7 0.0 0.078 12.1 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase TPMT PF05724.11 OAJ22259.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OAJ22259.1 - 0.047 13.2 0.1 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OAJ22259.1 - 0.063 12.6 0.0 0.45 9.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 OAJ22259.1 - 0.099 12.2 0.0 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Hydant_A_N PF05378.13 OAJ22260.1 - 3.4e-21 75.8 0.1 4.4e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Sorting_nexin PF03700.13 OAJ22261.1 - 0.038 14.5 3.9 0.05 14.2 3.6 1.3 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain Peptidase_C1_2 PF03051.15 OAJ22262.1 - 1.7e-32 112.8 0.0 1e-29 103.6 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Pectate_lyase_3 PF12708.7 OAJ22263.1 - 9.4e-79 264.2 9.8 2.1e-64 217.3 1.8 2.9 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAJ22263.1 - 0.00013 21.6 4.4 0.039 13.7 0.0 3.3 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 OAJ22263.1 - 0.011 15.6 2.3 0.043 13.7 1.9 2.3 2 0 0 2 2 2 0 Right handed beta helix region Sigma70_ner PF04546.13 OAJ22263.1 - 0.091 12.6 2.2 0.19 11.6 2.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.14 OAJ22263.1 - 1.7 8.4 5.7 3.1 7.5 5.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Calc_CGRP_IAPP PF00214.19 OAJ22264.1 - 0.01 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family SLM4 PF16818.5 OAJ22264.1 - 0.02 14.9 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein SLM4 Glyco_tran_28_C PF04101.16 OAJ22265.1 - 4.7e-22 78.7 0.0 6.5e-22 78.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RVT_2 PF07727.14 OAJ22266.1 - 2.2e-28 99.6 0.0 3.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ22266.1 - 0.0028 17.5 0.8 0.0086 15.9 0.8 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like RAI16-like PF10257.9 OAJ22267.1 - 1.1e-52 179.2 0.0 2.9e-52 177.8 0.0 1.7 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Pox_Ag35 PF03286.14 OAJ22267.1 - 0.075 12.8 1.9 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PGA2 PF07543.12 OAJ22267.1 - 4 7.4 14.8 3.1 7.8 0.4 3.7 3 0 0 3 3 3 0 Protein trafficking PGA2 Apt1 PF10351.9 OAJ22267.1 - 4.1 6.1 10.8 3.9 6.2 1.3 3.1 3 0 0 3 3 3 0 Golgi-body localisation protein domain Sigma70_ner PF04546.13 OAJ22267.1 - 7.5 6.4 11.3 0.83 9.5 1.9 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region TPR_2 PF07719.17 OAJ22268.1 - 4.2e-05 23.3 9.4 1.5 9.1 2.2 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ22268.1 - 0.00014 22.1 21.7 1.5 9.2 5.0 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ22268.1 - 0.0084 16.4 0.1 13 6.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ22268.1 - 0.017 15.9 13.2 2.8 9.0 0.0 6.6 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ22268.1 - 0.025 14.4 8.7 1.7 8.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ22268.1 - 0.036 14.1 0.1 0.36 10.9 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OAJ22268.1 - 0.043 13.7 16.6 1.1 9.2 1.6 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ22268.1 - 0.048 13.9 6.8 7.8 6.8 0.0 5.2 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OAJ22268.1 - 0.054 13.6 2.1 15 5.8 0.0 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 OAJ22268.1 - 0.075 13.1 7.3 22 5.3 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ22268.1 - 0.095 13.0 4.9 6.8 7.2 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ22268.1 - 0.72 10.7 11.6 3.4 8.6 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ22268.1 - 3 8.4 17.4 24 5.5 0.8 7.1 6 2 0 6 6 6 0 Tetratricopeptide repeat RAI16-like PF10257.9 OAJ22269.1 - 1.8e-07 30.4 0.0 1.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TPR_14 PF13428.6 OAJ22272.1 - 8.2e-06 26.2 42.1 4 8.5 0.0 13.3 11 4 2 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 OAJ22272.1 - 5.2e-05 23.4 3.0 0.12 12.4 0.1 4.6 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 OAJ22272.1 - 0.0066 16.7 9.9 17 6.0 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAJ22272.1 - 0.13 12.3 7.5 0.22 11.5 0.2 5.0 8 0 0 8 8 8 0 Mad3/BUB1 homology region 1 HAT PF02184.16 OAJ22272.1 - 0.49 10.4 8.1 2.9 7.9 0.1 5.7 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 OAJ22272.1 - 0.93 9.8 19.5 5.8 7.3 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ22272.1 - 5.5 7.8 9.7 2e+02 2.9 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3246 PF11596.8 OAJ22272.1 - 9.6 5.6 7.6 6.8 6.0 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Hus1 PF04005.12 OAJ22274.1 - 7e-71 238.7 0.1 8.6e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 Hus1-like protein DUF1681 PF07933.14 OAJ22275.1 - 4.3e-50 169.3 0.0 5e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Ribonuclease_T2 PF00445.18 OAJ22346.1 - 1.8e-30 106.5 0.0 2.7e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Melibiase PF02065.18 OAJ22346.1 - 0.12 11.4 0.0 0.95 8.3 0.0 1.9 2 0 0 2 2 2 0 Melibiase Cyt-b5 PF00173.28 OAJ22347.1 - 1.2e-19 70.2 0.1 2.3e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 OAJ22347.1 - 0.57 10.5 2.6 0.93 9.8 0.5 2.2 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily SHMT PF00464.19 OAJ22348.1 - 5.7e-167 555.3 0.0 6.7e-167 555.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OAJ22348.1 - 0.006 15.9 0.1 0.011 15.0 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAJ22348.1 - 0.023 13.9 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TspO_MBR PF03073.15 OAJ22349.1 - 1.1e-38 132.3 12.9 1.3e-38 132.1 12.9 1.0 1 0 0 1 1 1 1 TspO/MBR family PDH PF02153.17 OAJ22350.1 - 2.1e-13 49.9 0.0 2.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 OAJ22350.1 - 7.2e-08 32.9 0.4 1.8e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAJ22350.1 - 0.00014 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAJ22350.1 - 0.0002 21.4 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ22350.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAJ22350.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 OAJ22350.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ22350.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rad21_Rec8_N PF04825.13 OAJ22351.1 - 1.1e-38 131.8 0.0 2e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAJ22351.1 - 5.7e-15 54.3 1.3 8.8e-15 53.7 0.1 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 OAJ22351.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA A_deaminase PF00962.22 OAJ22352.1 - 2.1e-26 93.1 0.0 3.7e-26 92.2 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 OAJ22352.1 - 2.2e-05 24.6 0.0 4.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal NOB1_Zn_bind PF08772.11 OAJ22354.1 - 2.3e-30 104.6 1.2 4.3e-30 103.7 1.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAJ22354.1 - 5.5e-26 90.9 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease Nudix_N_2 PF14803.6 OAJ22354.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.11 OAJ22354.1 - 2.1 8.1 5.1 1.3 8.8 0.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain GTP_EFTU PF00009.27 OAJ22355.1 - 2.3e-50 170.9 0.0 3.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAJ22355.1 - 3.1e-38 130.2 0.1 5.7e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAJ22355.1 - 1.4e-12 47.4 0.0 3.9e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ22355.1 - 8.8e-07 29.2 0.2 1.8e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ22355.1 - 8.8e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 OAJ22355.1 - 0.00036 20.6 0.0 0.0009 19.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 OAJ22355.1 - 0.0037 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 OAJ22355.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain IMUP PF15761.5 OAJ22355.1 - 5 7.9 11.5 3.6 8.3 4.9 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein Dimer_Tnp_hAT PF05699.14 OAJ22356.1 - 2.2e-15 56.2 0.1 5.8e-15 54.8 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 OAJ22357.1 - 8.2e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glutenin_hmw PF03157.13 OAJ22358.1 - 0.00061 18.4 6.5 0.00077 18.0 6.5 1.0 1 0 0 1 1 1 1 High molecular weight glutenin subunit Amelogenin PF02948.15 OAJ22358.1 - 0.13 12.9 14.7 0.19 12.4 14.7 1.1 1 0 0 1 1 1 0 Amelogenin FdhE PF04216.12 OAJ22359.1 - 0.02 14.8 0.2 0.028 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation adh_short PF00106.25 OAJ22360.1 - 1.9e-17 63.4 0.3 2e-17 63.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ22360.1 - 1e-14 54.7 0.2 1.4e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-synt_DE_N PF02823.16 OAJ22361.1 - 0.00054 19.8 0.0 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Kinesin PF00225.23 OAJ22436.1 - 1.8e-105 352.6 0.1 4.4e-105 351.3 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ22436.1 - 2e-26 92.7 0.0 5.1e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Type2_restr_D3 PF16902.5 OAJ22436.1 - 0.066 13.1 0.0 0.48 10.4 0.0 2.5 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain LapA_dom PF06305.11 OAJ22437.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HemY_N PF07219.13 OAJ22437.1 - 0.58 10.4 1.6 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus Gcd10p PF04189.13 OAJ22438.1 - 5.3e-64 216.2 0.0 9.4e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family Ribosomal_S10 PF00338.22 OAJ22439.1 - 1.8e-27 95.4 0.2 2.2e-27 95.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Aminotran_3 PF00202.21 OAJ22440.1 - 3.9e-35 121.3 0.0 1.2e-16 60.4 0.0 3.4 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 OAJ22440.1 - 7.9e-12 45.4 0.0 4.2e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain GST_N PF02798.20 OAJ22441.1 - 2.5e-15 56.5 0.0 3e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ22441.1 - 2e-14 53.7 0.0 2.5e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ22441.1 - 1.5e-10 41.2 0.0 1.9e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OAJ22441.1 - 0.087 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin DUF2076 PF09849.9 OAJ22442.1 - 0.0056 16.8 0.4 0.0094 16.0 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Clr2_transil PF16761.5 OAJ22444.1 - 9.2e-08 32.8 1.3 1.7e-07 32.0 1.3 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAJ22444.1 - 0.00023 22.0 0.0 0.00045 21.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ABC_tran PF00005.27 OAJ22445.1 - 1.2e-44 152.2 0.0 1.2e-23 84.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAJ22445.1 - 1.9e-16 60.7 0.3 0.0023 17.8 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ22445.1 - 1.9e-10 40.6 0.0 0.014 14.8 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ22445.1 - 1.4e-08 35.5 0.0 0.0013 19.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 OAJ22445.1 - 1.3e-06 28.2 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 OAJ22445.1 - 2.1e-06 27.4 0.1 0.076 12.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_EZ PF13513.6 OAJ22445.1 - 4.1e-05 24.0 6.9 5.9 7.5 0.2 6.4 5 1 0 5 5 5 1 HEAT-like repeat AAA_16 PF13191.6 OAJ22445.1 - 4.6e-05 23.9 4.0 0.027 14.9 0.0 4.3 4 1 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ22445.1 - 5e-05 23.4 0.0 0.017 15.2 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ22445.1 - 7.2e-05 23.1 0.1 1.3 9.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain HEAT PF02985.22 OAJ22445.1 - 0.00014 21.8 5.3 3 8.4 0.1 6.1 6 0 0 6 6 5 1 HEAT repeat AAA_28 PF13521.6 OAJ22445.1 - 0.00024 21.4 0.1 3.6 7.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain HEAT_2 PF13646.6 OAJ22445.1 - 0.0003 21.1 10.4 0.025 15.0 1.1 5.0 4 2 2 6 6 4 2 HEAT repeats RsgA_GTPase PF03193.16 OAJ22445.1 - 0.0016 18.4 0.2 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OAJ22445.1 - 0.0036 17.5 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ22445.1 - 0.0042 16.8 0.2 0.86 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OAJ22445.1 - 0.0055 16.6 0.1 3.7 7.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain MeaB PF03308.16 OAJ22445.1 - 0.0055 15.7 0.4 0.53 9.2 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Adaptin_N PF01602.20 OAJ22445.1 - 0.0056 15.3 0.7 0.13 10.8 0.7 2.5 1 1 0 1 1 1 1 Adaptin N terminal region AAA_15 PF13175.6 OAJ22445.1 - 0.0058 16.4 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Cnd1 PF12717.7 OAJ22445.1 - 0.012 15.7 0.4 1 9.4 0.0 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 AAA_24 PF13479.6 OAJ22445.1 - 0.012 15.3 0.1 3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAJ22445.1 - 0.023 14.8 0.7 9.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 OAJ22445.1 - 0.046 14.3 0.1 11 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 OAJ22445.1 - 0.05 13.2 0.1 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.8 OAJ22445.1 - 0.067 12.8 0.2 1.7 8.2 0.1 2.7 1 1 1 2 2 2 0 CLASP N terminal Zeta_toxin PF06414.12 OAJ22445.1 - 0.1 11.8 0.2 23 4.2 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.14 OAJ22445.1 - 0.16 11.1 0.1 17 4.5 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain Dopey_N PF04118.14 OAJ22445.1 - 0.17 11.0 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Dopey, N-terminal RNA_helicase PF00910.22 OAJ22445.1 - 0.2 12.1 0.0 7.5 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase MFS_1 PF07690.16 OAJ22446.1 - 3.4e-33 115.0 27.5 3.4e-33 115.0 27.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FCH PF00611.23 OAJ22447.1 - 7.4e-16 58.2 1.8 1.6e-14 54.0 0.1 3.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SUI1 PF01253.22 OAJ22448.1 - 2.3e-12 47.3 0.1 4.4e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 YscO PF07321.12 OAJ22448.1 - 0.012 15.6 2.8 0.021 14.8 2.8 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO GA PF01468.17 OAJ22448.1 - 0.78 10.1 7.6 0.18 12.1 1.9 2.7 3 0 0 3 3 3 0 GA module BRO1 PF03097.18 OAJ22449.1 - 6.1e-103 344.6 0.0 1.5e-102 343.3 0.0 1.7 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAJ22449.1 - 7e-68 229.1 13.3 7e-68 229.1 13.3 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CAP_N PF01213.19 OAJ22449.1 - 0.0068 15.9 2.7 0.016 14.8 2.7 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF3294 PF07957.11 OAJ22449.1 - 0.032 14.0 2.1 0.073 12.8 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) ABC_tran_CTD PF16326.5 OAJ22449.1 - 1.1 9.6 8.0 0.23 11.7 0.3 3.3 2 2 1 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 OAJ22449.1 - 7.1 5.9 10.5 6.1 6.1 4.3 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PI-PLC-C1 PF16670.5 OAJ22450.1 - 0.0026 16.9 0.4 1.4 7.9 0.0 2.4 1 1 1 2 2 2 2 Phosphoinositide phospholipase C, Ca2+-dependent PI-PLC-C1 PF16670.5 OAJ22451.1 - 0.021 13.9 0.1 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent GCV_H PF01597.19 OAJ22517.1 - 1.8e-40 137.7 0.9 2.1e-40 137.4 0.9 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OAJ22517.1 - 0.0014 18.4 0.3 0.0031 17.3 0.3 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme GP70 PF17429.2 OAJ22517.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Gene product 70 RnfC_N PF13375.6 OAJ22517.1 - 0.0051 16.7 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain TfoX_C PF04994.13 OAJ22517.1 - 0.089 12.9 0.0 2.3 8.3 0.0 2.4 1 1 1 2 2 2 0 TfoX C-terminal domain tRNA_m1G_MT PF01746.21 OAJ22518.1 - 3.4e-17 62.8 0.3 1.3e-12 47.8 0.0 3.2 3 0 0 3 3 3 3 tRNA (Guanine-1)-methyltransferase FA_hydroxylase PF04116.13 OAJ22519.1 - 3.2e-19 69.6 10.3 3.2e-19 69.6 10.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1772 PF08592.11 OAJ22519.1 - 0.0055 17.0 8.1 0.08 13.3 0.5 3.2 2 1 0 3 3 3 2 Domain of unknown function (DUF1772) zf-CSL PF05207.13 OAJ22520.1 - 4.5e-22 77.5 0.9 7.7e-22 76.8 0.9 1.4 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 OAJ22520.1 - 0.00067 19.7 0.5 0.0012 18.9 0.5 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 OAJ22520.1 - 0.0071 16.2 1.0 0.011 15.6 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.6 OAJ22520.1 - 0.035 13.9 0.5 0.069 13.0 0.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_7 PF02591.15 OAJ22520.1 - 0.046 13.9 0.3 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain Sad1_UNC PF07738.13 OAJ22521.1 - 1.3e-19 70.6 0.0 4.8e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF2849 PF11011.8 OAJ22521.1 - 5.4 7.8 9.8 2.4 8.9 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) DUF1768 PF08719.11 OAJ22523.1 - 6.8e-24 84.9 0.0 8.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OAJ22523.1 - 0.0024 17.7 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 Bacteriophage protein GP30.3 zf-Tim10_DDP PF02953.15 OAJ22524.1 - 1.2e-18 66.5 4.5 1.2e-18 66.5 4.5 1.8 2 1 1 3 3 3 1 Tim10/DDP family zinc finger Syja_N PF02383.18 OAJ22525.1 - 2.9e-87 293.0 0.0 3.6e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Hydrolase_4 PF12146.8 OAJ22526.1 - 2.2e-15 56.6 0.0 6.3e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ22526.1 - 3.9e-13 49.6 0.4 7.9e-08 32.3 0.3 2.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAJ22526.1 - 2.1e-06 26.7 0.0 0.0064 15.2 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAJ22526.1 - 0.0012 19.5 3.2 0.0012 19.5 3.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OAJ22526.1 - 0.0027 17.6 0.0 0.033 14.1 0.0 2.5 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OAJ22526.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 OAJ22526.1 - 0.029 13.9 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 OAJ22526.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ub-Mut7C PF14451.6 OAJ22526.1 - 0.077 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin PAP2 PF01569.21 OAJ22528.1 - 0.026 14.3 1.2 0.026 14.3 1.2 3.4 2 1 1 3 3 3 0 PAP2 superfamily Wzy_C PF04932.15 OAJ22528.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.7 2 1 0 2 2 2 0 O-Antigen ligase Med13_C PF06333.12 OAJ22529.1 - 1.9 7.7 4.4 2.7 7.2 4.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DEAD PF00270.29 OAJ22530.1 - 1e-08 35.2 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ22530.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Spb1_C PF07780.12 OAJ22531.1 - 1.2e-73 247.2 27.2 1.2e-73 247.2 27.2 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAJ22531.1 - 1e-55 188.6 0.2 4.1e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAJ22531.1 - 8e-40 136.3 10.7 8e-40 136.3 10.7 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) Rtf2 PF04641.12 OAJ22532.1 - 2.2e-55 187.8 0.0 9.1e-55 185.8 0.0 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger SUIM_assoc PF16619.5 OAJ22602.1 - 0.0084 16.2 1.6 0.0084 16.2 1.6 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 OAJ22602.1 - 0.055 13.6 7.8 0.14 12.3 7.4 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAJ22602.1 - 1.2 8.7 7.7 2.7 7.5 7.7 1.5 1 0 0 1 1 1 0 Spt20 family Syndecan PF01034.20 OAJ22603.1 - 0.15 12.0 0.5 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain MAT1 PF06391.13 OAJ22604.1 - 4.2e-41 141.0 3.8 6.4e-41 140.4 3.8 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAJ22604.1 - 3.8e-17 61.9 7.5 5.9e-17 61.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ22604.1 - 0.00019 21.2 8.1 0.00041 20.1 8.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ22604.1 - 0.00021 21.1 2.1 0.00021 21.1 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ22604.1 - 0.0011 19.2 6.7 0.002 18.4 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAJ22604.1 - 0.0019 18.1 8.3 0.0058 16.6 8.6 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 OAJ22604.1 - 0.024 14.4 8.4 0.072 12.9 4.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAJ22604.1 - 0.17 11.6 3.5 0.27 10.9 3.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 OAJ22604.1 - 0.38 10.8 7.4 0.74 9.9 7.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-UDP PF14569.6 OAJ22604.1 - 1.1 9.4 5.3 7.3 6.8 1.6 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 OAJ22604.1 - 3.2 8.0 9.9 31 4.8 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_4 PF14447.6 OAJ22604.1 - 3.4 7.6 12.0 12 5.9 12.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FAD_binding_3 PF01494.19 OAJ22605.1 - 5.8e-22 78.4 0.3 1.7e-11 44.0 0.0 3.3 2 2 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ22605.1 - 2.4e-06 27.4 0.1 6.6e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ22605.1 - 2.7e-06 27.5 0.0 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ22605.1 - 0.00051 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ22605.1 - 0.0008 18.7 0.0 0.0017 17.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAJ22605.1 - 0.0011 18.0 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase HI0933_like PF03486.14 OAJ22605.1 - 0.0013 17.5 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 OAJ22605.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAJ22605.1 - 0.0046 16.1 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAJ22605.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAJ22605.1 - 0.095 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAJ22605.1 - 0.27 10.5 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PBP PF01161.20 OAJ22606.1 - 6.3e-10 39.5 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein KfrB PF18790.1 OAJ22606.1 - 0.057 13.7 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 KfrB protein PRR18 PF15671.5 OAJ22606.1 - 4.8 7.0 8.1 10 5.9 8.1 1.5 1 0 0 1 1 1 0 Proline-rich protein family 18 ALG3 PF05208.13 OAJ22607.1 - 5.4e-131 437.3 6.1 6.7e-131 437.0 6.1 1.1 1 0 0 1 1 1 1 ALG3 protein Drc1-Sld2 PF11719.8 OAJ22608.1 - 2.5e-11 43.8 10.9 2.5e-11 43.8 10.9 5.5 4 2 2 6 6 6 1 DNA replication and checkpoint protein Clathrin PF00637.20 OAJ22609.1 - 5.7e-15 55.4 0.4 3.5e-06 26.9 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.8 OAJ22609.1 - 8.7e-11 41.9 0.5 8.7e-11 41.9 0.5 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 OAJ22609.1 - 1.1e-09 38.2 7.0 2.5e-09 37.0 7.0 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 OAJ22609.1 - 0.0032 17.3 7.3 0.0054 16.5 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ22609.1 - 0.054 13.8 6.5 0.096 13.0 6.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OAJ22609.1 - 0.14 12.1 6.5 0.24 11.4 6.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.22 OAJ22609.1 - 1.2 9.1 6.9 2.3 8.2 6.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 OAJ22609.1 - 1.4 9.0 5.7 2.9 8.0 5.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ22609.1 - 7.2 6.6 6.6 13 5.8 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 2-oxoacid_dh PF00198.23 OAJ22610.1 - 4.4e-53 180.1 0.0 9.8e-53 179.0 0.0 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ22610.1 - 4.7e-19 68.0 0.1 7.3e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAJ22610.1 - 4.2e-15 55.8 0.1 1.1e-14 54.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAJ22610.1 - 0.023 14.5 0.0 0.082 12.7 0.0 1.9 1 1 1 2 2 2 0 Biotin-lipoyl like PYNP_C PF07831.13 OAJ22610.1 - 0.087 12.5 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.7 OAJ22610.1 - 0.12 11.1 0.0 0.39 9.4 0.0 1.6 1 1 1 2 2 2 0 HlyD family secretion protein Nop25 PF09805.9 OAJ22611.1 - 3.4e-19 69.7 14.8 3.4e-19 69.7 14.8 2.6 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) ALC PF17527.2 OAJ22611.1 - 1.8 8.2 14.9 0.2 11.3 5.8 2.2 1 1 0 2 2 2 0 Phage ALC protein CNDH2_C PF16858.5 OAJ22611.1 - 2.1 8.1 14.8 0.22 11.3 10.5 1.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RTA1 PF04479.13 OAJ22613.1 - 3.7e-48 163.9 10.2 5.5e-48 163.3 10.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Phage_integrase PF00589.22 OAJ22615.1 - 9.6e-06 25.5 0.0 5.7e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Phage integrase family RVT_1 PF00078.27 OAJ22616.1 - 3.7e-31 108.4 0.0 5.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ22616.1 - 4.7e-11 42.6 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ22616.1 - 2.3e-06 27.3 1.8 6.4e-06 25.9 0.1 2.6 3 1 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 OAJ22617.1 - 6.5e-09 36.1 0.1 1.4e-08 35.0 0.1 1.6 1 1 0 1 1 1 1 RNase H Tam41_Mmp37 PF09139.11 OAJ22688.1 - 6.6e-105 351.1 0.0 1.1e-104 350.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF4667 PF15700.5 OAJ22688.1 - 0.027 14.6 13.7 0.047 13.8 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SPX PF03105.19 OAJ22688.1 - 0.1 12.5 15.4 0.16 11.9 15.4 1.3 1 0 0 1 1 1 0 SPX domain Herpes_pp85 PF04637.12 OAJ22688.1 - 0.88 7.9 11.4 1.3 7.3 11.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HlyIII PF03006.20 OAJ22691.1 - 4e-48 164.1 23.6 1.2e-47 162.5 23.6 1.8 1 1 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.15 OAJ22691.1 - 0.086 13.1 3.4 0.079 13.2 0.9 2.3 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Form-deh_trans PF09163.11 OAJ22691.1 - 0.11 12.3 3.9 5.1 7.0 0.1 3.3 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Cation_ATPase_C PF00689.21 OAJ22691.1 - 0.17 11.6 6.6 0.37 10.5 0.3 2.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_4 PF01565.23 OAJ22693.1 - 3.2e-16 59.3 5.7 3.3e-09 36.6 0.0 3.9 4 0 0 4 4 4 2 FAD binding domain BBE PF08031.12 OAJ22693.1 - 1.2e-06 28.6 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Med3 PF11593.8 OAJ22693.1 - 0.062 12.5 15.4 0.11 11.7 15.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MCLC PF05934.11 OAJ22693.1 - 4.5 5.9 10.4 6.7 5.3 10.4 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) SMC_N PF02463.19 OAJ22696.1 - 1.3e-68 230.8 0.0 1.9e-68 230.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ22696.1 - 7.1e-29 100.5 0.2 2.1e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ22696.1 - 1.7e-18 67.8 13.3 1.7e-18 67.8 13.3 7.1 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.6 OAJ22696.1 - 1.5e-17 64.4 24.8 1.7e-13 51.0 6.4 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 OAJ22696.1 - 5.3e-13 49.5 8.0 1.4e-06 28.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ22696.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAJ22696.1 - 0.12 11.8 0.0 0.12 11.8 0.0 3.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 OAJ22696.1 - 0.21 12.1 19.5 5 7.6 4.9 5.2 3 2 0 3 3 3 0 ABC transporter HMA PF00403.26 OAJ22696.1 - 2.4 8.7 4.2 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 Heavy-metal-associated domain YebO PF13974.6 OAJ22697.1 - 5.4 7.2 6.4 0.77 9.9 0.1 2.3 2 0 0 2 2 2 0 YebO-like protein SNF2_N PF00176.23 OAJ22698.1 - 8.7e-61 205.6 0.0 1.5e-30 106.1 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 OAJ22698.1 - 3.9e-11 42.6 4.9 7.3e-11 41.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 OAJ22698.1 - 6e-11 42.7 0.0 6.1e-09 36.2 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 OAJ22698.1 - 4.7e-09 36.0 5.3 9.1e-09 35.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ22698.1 - 1e-07 32.1 4.9 2.1e-07 31.2 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ22698.1 - 1.1e-07 31.7 7.0 2.6e-07 30.5 7.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ22698.1 - 8.5e-07 28.7 2.6 1.6e-06 27.8 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ22698.1 - 4.7e-06 26.7 7.7 1e-05 25.6 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ22698.1 - 6.2e-05 22.8 3.8 0.00014 21.6 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ22698.1 - 9.6e-05 22.3 2.8 0.00021 21.2 2.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAJ22698.1 - 0.00054 20.2 2.7 0.0019 18.5 2.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAJ22698.1 - 0.058 13.3 2.4 0.13 12.1 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OAJ22698.1 - 0.2 11.5 6.0 0.42 10.4 6.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 OAJ22698.1 - 0.27 11.4 2.5 0.68 10.1 2.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 FGGY_C PF02782.16 OAJ22699.1 - 1.3e-44 152.3 0.1 2e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAJ22699.1 - 2.2e-22 79.8 0.0 1e-21 77.6 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAJ22699.1 - 3e-05 23.6 0.2 8.4e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 OAJ22699.1 - 0.00079 19.4 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 Hexokinase Response_reg PF00072.24 OAJ22789.1 - 6.5e-23 81.0 0.0 1.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAJ22789.1 - 1.8e-17 63.8 0.0 3.5e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAJ22789.1 - 4.8e-10 39.3 0.1 2e-09 37.4 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Phosducin PF02114.16 OAJ22790.1 - 0.023 13.7 0.8 4.4 6.2 0.5 2.3 2 0 0 2 2 2 0 Phosducin Pap_E4 PF02711.14 OAJ22790.1 - 5.4 8.1 7.3 1.6 9.7 3.0 2.2 2 0 0 2 2 2 0 E4 protein Linker_histone PF00538.19 OAJ22792.1 - 0.012 16.0 0.0 0.13 12.6 0.0 2.4 1 1 0 1 1 1 0 linker histone H1 and H5 family Presenilin PF01080.17 OAJ22792.1 - 2.6 6.7 3.4 4 6.1 3.4 1.2 1 0 0 1 1 1 0 Presenilin FKBP_C PF00254.28 OAJ22793.1 - 7e-34 116.0 0.0 8.1e-34 115.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 OAJ22795.1 - 3.6e-31 107.3 0.0 4.1e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Metallophos PF00149.28 OAJ22796.1 - 1.4e-10 42.0 0.0 2.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ferric_reduct PF01794.19 OAJ22797.1 - 1.2e-23 83.6 11.3 1.2e-23 83.6 11.3 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ22797.1 - 2.2e-17 63.6 0.0 3.2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ22797.1 - 4.1e-10 39.7 0.0 9.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAJ22797.1 - 0.0064 17.1 0.0 0.063 13.9 0.0 2.2 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain ssDBP PF17878.1 OAJ22798.1 - 0.066 13.5 0.3 0.09 13.0 0.3 1.2 1 0 0 1 1 1 0 Single-stranded DNA-binding protein Ferritin_2 PF13668.6 OAJ22799.1 - 1e-10 42.0 0.0 1.3e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Keratin_2_head PF16208.5 OAJ22802.1 - 7.5 6.7 19.4 1 9.5 10.0 2.2 2 0 0 2 2 2 0 Keratin type II head UPF0565 PF10561.9 OAJ22802.1 - 8.2 5.5 7.2 0.64 9.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 SNARE_assoc PF09335.11 OAJ22804.1 - 1.4e-12 48.2 4.5 1.4e-12 48.2 4.5 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Nop14 PF04147.12 OAJ22804.1 - 4.4 5.4 10.2 8.1 4.5 10.2 1.3 1 0 0 1 1 1 0 Nop14-like family HAD PF12710.7 OAJ22805.1 - 4.3e-05 24.0 0.0 0.16 12.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MASE2 PF05230.11 OAJ22897.1 - 0.023 14.8 0.3 0.023 14.8 0.3 1.8 2 0 0 2 2 2 0 MASE2 domain DUF2651 PF10852.8 OAJ22897.1 - 1.5 9.5 14.1 0.14 12.8 2.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2651) DUF1768 PF08719.11 OAJ22898.1 - 5.9e-09 36.4 1.4 9.2e-09 35.7 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UPF0167 PF03691.14 OAJ22898.1 - 0.078 12.8 0.4 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) UCH PF00443.29 OAJ22899.1 - 2.6e-38 132.0 0.0 3.7e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ22899.1 - 5.5e-08 32.8 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Herpes_BLRF2 PF05812.12 OAJ22899.1 - 0.003 17.7 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DNApol_Exo PF18136.1 OAJ22900.1 - 3.2e-81 272.6 0.1 7.7e-71 238.5 0.0 3.4 2 1 0 2 2 2 2 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAJ22900.1 - 1.2e-46 159.5 0.2 9e-46 156.6 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family A PARP PF00644.20 OAJ22901.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 OAJ22902.1 - 3.4e-22 79.4 0.0 5.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1769 PF08588.10 OAJ22904.1 - 8.1e-23 80.4 0.2 1.7e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Glyco_hydro_3_C PF01915.22 OAJ22905.1 - 3.8e-50 170.7 0.0 7.7e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAJ22905.1 - 8e-39 133.9 0.0 1.4e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAJ22905.1 - 3.7e-19 68.6 0.0 8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain P34-Arc PF04045.14 OAJ22906.1 - 7.8e-108 359.7 1.0 1e-107 359.3 0.0 1.7 2 0 0 2 2 2 1 Arp2/3 complex, 34 kD subunit p34-Arc XRN_M PF17846.1 OAJ22906.1 - 3.5e-105 352.5 0.1 9.7e-105 351.1 0.1 1.6 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 OAJ22906.1 - 5.7e-92 307.5 0.0 1.1e-91 306.6 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 OAJ22906.1 - 1.7e-67 226.9 0.0 3.3e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 OAJ22906.1 - 1.1e-22 80.1 0.0 2.6e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 OAJ22906.1 - 6.1e-19 67.9 0.3 1.9e-18 66.3 0.1 2.0 2 0 0 2 2 2 1 Xrn1 SH3-like domain adh_short PF00106.25 OAJ22907.1 - 8e-41 139.6 0.1 1.1e-40 139.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ22907.1 - 2.4e-21 76.4 0.0 3.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ22907.1 - 0.00018 21.5 0.0 0.00036 20.5 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF4078 PF13300.6 OAJ22908.1 - 1.2e-15 57.6 4.0 1.2e-15 57.6 0.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) Exo_endo_phos PF03372.23 OAJ22909.1 - 4.9e-06 26.2 0.0 1.5e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cys_Met_Meta_PP PF01053.20 OAJ22910.1 - 4e-21 75.0 0.0 2.5e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAJ22910.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SelK_SelG PF10961.8 OAJ22910.1 - 0.84 10.3 3.8 3.3 8.4 3.8 2.0 1 0 0 1 1 1 0 Selenoprotein SelK_SelG An_peroxidase PF03098.15 OAJ22916.1 - 6.9e-38 130.5 0.9 4.6e-20 71.7 0.0 4.0 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 OAJ22916.1 - 1.4e-12 47.2 0.0 2.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 OAJ22917.1 - 7.4e-85 284.8 0.0 1.6e-84 283.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 OAJ22917.1 - 0.028 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ribosomal_L30_N PF08079.12 OAJ22917.1 - 2.2 8.6 7.6 0.091 13.0 1.7 1.6 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Cutinase PF01083.22 OAJ22918.1 - 2e-20 73.5 0.0 2.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 OAJ22918.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 OAJ22918.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase PE-PPE PF08237.11 OAJ22918.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.22 OAJ22919.1 - 1.7e-23 83.5 0.0 4.5e-23 82.1 0.0 1.6 1 1 0 1 1 1 1 Cutinase FSH1 PF03959.13 OAJ22919.1 - 0.0029 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OAJ22919.1 - 0.007 16.0 0.0 0.011 15.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.11 OAJ22919.1 - 0.056 13.0 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF676 PF05057.14 OAJ22919.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 OAJ22919.1 - 0.09 12.4 0.0 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase BAR_3_WASP_bdg PF10456.9 OAJ22921.1 - 2e-08 34.0 0.5 7.8e-08 32.1 0.5 1.8 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 OAJ22922.1 - 6.4e-17 61.6 0.1 5.1e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 PX domain SH3_1 PF00018.28 OAJ22922.1 - 1.3e-05 24.7 0.0 2.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Zn_clus PF00172.18 OAJ22923.1 - 1.7e-05 24.8 10.2 2.7e-05 24.2 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3684 PF12449.8 OAJ22924.1 - 5.6e-294 978.1 0.2 1.2e-276 920.7 0.0 4.1 2 2 0 2 2 2 2 Protein of unknown function (DUF3684) EMC3_TMCO1 PF01956.16 OAJ22925.1 - 3.4e-57 192.9 0.7 4.2e-57 192.6 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Cwf_Cwc_15 PF04889.12 OAJ22927.1 - 3.1e-74 249.8 20.4 4.2e-74 249.4 20.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAJ22927.1 - 0.36 9.0 36.5 0.46 8.6 36.5 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ22927.1 - 6.2 6.0 29.2 8.8 5.5 29.2 1.3 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 OAJ22928.1 - 6.5e-10 39.4 4.0 0.016 16.0 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ22928.1 - 0.00028 21.1 0.0 1.6 9.0 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ22928.1 - 0.014 14.4 0.0 0.23 10.4 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MULE PF10551.9 OAJ22929.1 - 1.2e-22 80.1 0.0 3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ22929.1 - 9.4e-06 24.7 0.2 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.15 OAJ22929.1 - 0.25 12.1 1.7 0.62 10.8 1.7 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain p450 PF00067.22 OAJ22930.1 - 3.4e-63 214.0 0.0 8e-63 212.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAJ22931.1 - 4.9e-63 213.5 0.0 1e-62 212.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Stress-antifung PF01657.17 OAJ22937.1 - 0.03 14.9 6.1 0.035 14.7 6.1 1.1 1 0 0 1 1 1 0 Salt stress response/antifungal TRAPPC10 PF12584.8 OAJ22938.1 - 4.5e-25 88.2 0.0 9.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gpi1 PF05024.15 OAJ22939.1 - 7.6e-55 185.9 0.5 1.2e-54 185.3 0.5 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) FXMR_C2 PF16098.5 OAJ22939.1 - 8.2 7.0 7.4 8.2 7.0 0.1 2.7 2 1 1 3 3 3 0 Fragile X-related mental retardation protein C-terminal region 2 FMO-like PF00743.19 OAJ22940.1 - 1.9e-33 115.7 0.0 5.9e-19 67.9 0.0 3.1 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAJ22940.1 - 3.9e-10 39.5 0.1 8e-05 22.0 0.0 3.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ22940.1 - 4.8e-06 25.9 0.1 0.0021 17.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAJ22940.1 - 9.1e-06 25.1 0.0 0.00019 20.8 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ22940.1 - 2.5e-05 24.3 0.0 0.00051 20.1 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ22940.1 - 0.0014 18.8 0.1 0.003 17.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ22940.1 - 0.0073 15.9 0.2 0.21 11.1 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ22940.1 - 0.017 14.4 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.15 OAJ22940.1 - 0.044 13.1 0.0 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DUF1279 PF06916.13 OAJ22941.1 - 0.022 15.3 0.0 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) MSA-2c PF12238.8 OAJ22941.1 - 0.93 9.5 5.7 1.6 8.7 5.7 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Aldo_ket_red PF00248.21 OAJ22942.1 - 1.1e-12 47.8 0.0 4.2e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family ELFV_dehydrog PF00208.21 OAJ22943.1 - 9e-51 172.9 0.0 1.3e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAJ22943.1 - 2.7e-19 68.3 0.0 8.4e-14 50.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase DNA_ligase_OB_2 PF14743.6 OAJ22945.1 - 1e-27 95.9 1.3 1.7e-27 95.2 0.3 1.9 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_OB_2 PF14743.6 OAJ22946.1 - 2.6e-28 97.8 0.3 7.8e-28 96.3 0.3 1.8 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 OAJ22946.1 - 1.4e-07 31.4 0.0 3.9e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OAJ22946.1 - 0.002 18.5 0.0 0.0046 17.3 0.0 1.6 1 1 0 1 1 1 1 RNA ligase SWIM PF04434.17 OAJ22946.1 - 0.0079 15.8 0.5 0.015 15.0 0.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger Peroxidase_2 PF01328.17 OAJ22947.1 - 1.5e-42 146.3 0.0 2.1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Transp_cyt_pur PF02133.15 OAJ22948.1 - 7.9e-129 430.3 42.5 2e-121 405.8 33.8 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Methyltransf_11 PF08241.12 OAJ22949.1 - 1.2e-21 77.2 0.0 3e-09 37.4 0.0 4.1 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ22949.1 - 4.3e-20 72.2 0.0 8e-08 32.9 0.0 5.0 3 2 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ22949.1 - 7.1e-13 49.2 0.0 0.00027 21.6 0.0 4.5 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ22949.1 - 4.3e-06 26.7 0.0 0.075 12.9 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22949.1 - 0.0094 15.8 0.0 13 5.6 0.0 3.9 3 1 0 3 3 3 1 Methyltransferase domain Neuro_bHLH PF12533.8 OAJ22949.1 - 0.061 14.5 0.0 13 6.9 0.0 2.5 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor Phage_int_SAM_1 PF02899.17 OAJ22949.1 - 0.25 11.7 0.4 0.6 10.5 0.0 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DCP2 PF05026.13 OAJ22949.1 - 0.94 9.8 3.7 15 6.0 1.1 2.9 2 1 0 2 2 2 0 Dcp2, box A domain Meth_synt_2 PF01717.18 OAJ22950.1 - 4.9e-150 499.2 0.0 1.6e-143 477.9 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAJ22950.1 - 2.9e-116 388.4 0.0 2.7e-110 368.8 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain TPR_MLP1_2 PF07926.12 OAJ22950.1 - 0.42 10.7 2.6 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein UQ_con PF00179.26 OAJ22951.1 - 2.4e-41 140.6 0.0 3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAJ22951.1 - 2.8e-21 75.0 0.1 4.2e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 OAJ22951.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain DUF1421 PF07223.11 OAJ22951.1 - 0.0031 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain (DUF1421) UBA PF00627.31 OAJ22951.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Sporozoite_P67 PF05642.11 OAJ22951.1 - 0.62 8.1 6.4 0.8 7.7 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gastrin PF00918.17 OAJ22952.1 - 0.071 14.1 6.0 0.086 13.8 6.0 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family TraV PF09676.10 OAJ22952.1 - 4.8 8.2 12.2 7 7.6 12.2 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) FHA PF00498.26 OAJ22954.1 - 2e-14 53.7 0.0 3.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ22954.1 - 0.0036 17.6 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Apt1 PF10351.9 OAJ22954.1 - 0.97 8.2 4.8 1.1 8.0 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EBV-NA3 PF05009.12 OAJ22956.1 - 0.076 12.5 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribosomal_L44 PF00935.19 OAJ22956.1 - 0.16 12.5 4.2 0.076 13.5 1.4 1.9 2 0 0 2 2 2 0 Ribosomal protein L44 FF PF01846.19 OAJ22957.1 - 2.4e-19 69.2 8.6 2.1e-08 34.2 0.1 4.9 5 1 0 5 5 5 2 FF domain WW PF00397.26 OAJ22957.1 - 8.2e-13 48.2 14.8 1.9e-06 27.8 2.2 2.6 2 0 0 2 2 2 2 WW domain DUF5338 PF17273.2 OAJ22957.1 - 0.0068 16.5 0.5 0.026 14.6 0.5 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5338) RhoGAP-FF1 PF16512.5 OAJ22957.1 - 0.02 15.5 0.3 0.02 15.5 0.3 3.0 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain DDE_3 PF13358.6 OAJ22958.1 - 3.9e-28 98.1 0.0 6.1e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ22958.1 - 0.00071 20.1 0.2 0.0019 18.8 0.2 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ22958.1 - 0.0019 17.8 0.2 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 OAJ22958.1 - 0.0032 17.6 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF3405 PF11885.8 OAJ22959.1 - 4.1e-81 273.1 7.2 5.8e-51 173.7 0.3 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3405) QueF_N PF14819.6 OAJ22960.1 - 0.19 12.1 0.2 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Aldo_ket_red PF00248.21 OAJ22961.1 - 1.9e-17 63.4 0.0 7.1e-13 48.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family AAA PF00004.29 OAJ22962.1 - 1.5e-47 161.3 0.0 3.2e-43 147.3 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAJ22962.1 - 2.5e-20 72.6 0.0 5.3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAJ22962.1 - 3.3e-14 52.4 3.3 6.4e-08 32.3 0.0 2.8 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 OAJ22962.1 - 9.1e-08 32.7 10.9 0.005 17.2 0.8 4.7 2 2 2 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 OAJ22962.1 - 1.5e-05 25.5 0.0 0.28 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAJ22962.1 - 3e-05 24.2 0.0 0.046 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ22962.1 - 3.5e-05 24.1 4.7 0.37 11.1 0.2 4.6 4 2 1 5 5 3 2 AAA domain AAA_5 PF07728.14 OAJ22962.1 - 8.5e-05 22.6 0.1 0.6 10.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ22962.1 - 0.00024 20.9 0.0 0.0034 17.1 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OAJ22962.1 - 0.00028 20.9 0.1 0.52 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 OAJ22962.1 - 0.00056 19.4 0.2 0.94 8.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OAJ22962.1 - 0.00059 19.5 4.5 1.7 8.1 0.5 4.4 2 2 0 3 3 3 1 AAA domain NACHT PF05729.12 OAJ22962.1 - 0.00081 19.3 1.7 5.4 6.9 0.2 4.2 4 0 0 4 4 4 0 NACHT domain RNA_helicase PF00910.22 OAJ22962.1 - 0.0018 18.6 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase APS_kinase PF01583.20 OAJ22962.1 - 0.0021 18.0 0.0 0.1 12.5 0.0 2.9 2 1 1 3 3 3 1 Adenylylsulphate kinase DUF2075 PF09848.9 OAJ22962.1 - 0.0027 17.0 0.0 0.62 9.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 OAJ22962.1 - 0.0028 17.9 0.3 2.6 8.3 0.4 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAJ22962.1 - 0.0035 17.1 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 OAJ22962.1 - 0.0038 17.7 0.1 0.48 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ22962.1 - 0.01 15.0 0.2 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_2 PF07724.14 OAJ22962.1 - 0.011 15.8 0.0 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 OAJ22962.1 - 0.016 14.9 0.1 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OAJ22962.1 - 0.023 14.6 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 OAJ22962.1 - 0.028 13.8 0.2 4.2 6.6 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 OAJ22962.1 - 0.035 13.6 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 OAJ22962.1 - 0.038 13.2 0.8 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 OAJ22962.1 - 0.047 13.4 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 OAJ22962.1 - 0.074 13.4 0.1 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ22962.1 - 0.084 12.0 0.2 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 OAJ22962.1 - 0.098 12.7 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAJ22962.1 - 0.13 11.3 0.2 0.57 9.2 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 OAJ22962.1 - 0.14 12.2 0.1 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain SKI PF01202.22 OAJ22962.1 - 0.18 11.9 0.2 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.6 OAJ22962.1 - 0.18 11.5 0.1 14 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ22962.1 - 0.3 10.9 1.7 2.3 8.0 1.5 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.6 OAJ22962.1 - 0.32 11.1 1.3 1.2 9.3 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase-like family Ribosomal_S11 PF00411.19 OAJ22963.1 - 2.4e-08 34.3 7.8 4.9e-08 33.3 0.7 3.1 3 1 0 3 3 3 1 Ribosomal protein S11 LEAP-2 PF07359.11 OAJ22964.1 - 0.089 12.6 0.3 0.089 12.6 0.3 5.1 5 0 0 5 5 5 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) MT-A70 PF05063.14 OAJ22965.1 - 4.4e-37 127.6 0.3 9.3e-27 94.0 0.1 2.9 2 1 0 2 2 2 2 MT-A70 RNase_PH PF01138.21 OAJ22967.1 - 4.5e-16 59.6 0.0 1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Amidohydro_1 PF01979.20 OAJ22968.1 - 4.6e-67 226.8 0.2 7.7e-67 226.0 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 OAJ22968.1 - 3.1e-58 195.4 0.6 9.9e-58 193.7 0.6 1.9 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 OAJ22968.1 - 8.1e-43 144.8 0.3 1.8e-42 143.6 0.3 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 OAJ22968.1 - 1.1e-35 121.5 0.0 2.9e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 OAJ22968.1 - 1.1e-07 31.7 0.1 6.4e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family HlyD_D4 PF16572.5 OAJ22968.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Vezatin PF12632.7 OAJ22969.1 - 3.5e-10 39.7 0.0 2.2e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Mysoin-binding motif of peroxisomes RRP36 PF06102.12 OAJ22970.1 - 1e-34 119.9 12.3 1e-34 119.9 12.3 3.6 3 1 0 3 3 3 2 rRNA biogenesis protein RRP36 Sugar_tr PF00083.24 OAJ22971.1 - 8.9e-106 354.4 13.8 1.1e-105 354.2 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ22971.1 - 4.4e-28 98.2 23.1 1.2e-27 96.8 23.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 OAJ22971.1 - 0.035 12.5 2.8 0.047 12.1 0.4 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 OAJ22971.1 - 5.3 7.4 5.8 0.83 9.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Aldo_ket_red PF00248.21 OAJ22972.1 - 1.2e-09 37.8 0.0 1.3e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 OAJ22976.1 - 8.9e-62 209.1 0.0 1.3e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ22976.1 - 3e-27 95.9 0.0 7e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ22976.1 - 7.3e-06 25.3 0.1 0.00088 18.5 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ22976.1 - 1.8e-05 24.9 0.1 7.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ22976.1 - 0.00018 21.2 2.2 0.00098 18.8 2.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ22976.1 - 0.00023 20.4 0.2 0.00034 19.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAJ22976.1 - 0.00059 19.2 0.8 0.13 11.5 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ22976.1 - 0.00096 18.0 0.5 0.0051 15.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAJ22976.1 - 0.0034 16.7 0.2 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ22976.1 - 0.047 12.9 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family RT_RNaseH_2 PF17919.1 OAJ22977.1 - 2.6e-29 101.2 0.0 5.5e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ22977.1 - 2.4e-27 95.3 0.0 4.6e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ22977.1 - 1.3e-13 51.2 0.0 5e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain p450 PF00067.22 OAJ22977.1 - 1.6e-12 46.9 0.0 2.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Integrase_H2C2 PF17921.1 OAJ22977.1 - 4.8e-12 45.8 0.0 9.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ22977.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.6 OAJ22978.1 - 0.0058 17.2 0.0 0.019 15.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 OAJ22978.1 - 0.0088 16.1 3.5 0.015 15.3 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 OAJ22978.1 - 0.22 11.0 0.0 0.42 10.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 OAJ22978.1 - 0.26 11.2 1.6 0.46 10.4 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle AP3D1 PF06375.11 OAJ22982.1 - 0.0058 16.9 5.1 0.0058 16.9 5.1 3.3 3 0 0 3 3 3 1 AP-3 complex subunit delta-1 Med19 PF10278.9 OAJ22982.1 - 0.15 12.0 8.8 0.35 10.8 8.8 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 OAJ22982.1 - 0.21 11.4 1.8 0.62 9.8 1.8 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 OAJ22982.1 - 0.28 11.3 1.1 0.95 9.5 1.1 2.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein PPL5 PF18168.1 OAJ22982.1 - 0.31 10.3 2.3 0.62 9.3 2.3 1.4 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 OAJ22982.1 - 0.36 9.1 2.4 0.94 7.7 2.4 1.7 1 0 0 1 1 1 0 CDC45-like protein DUF3464 PF11947.8 OAJ22982.1 - 0.56 10.0 2.3 3.1 7.6 2.3 2.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DNA_pol_phi PF04931.13 OAJ22982.1 - 0.56 8.2 4.0 0.99 7.4 4.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi NARP1 PF12569.8 OAJ22982.1 - 3 6.6 11.2 5.2 5.9 11.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DEAD PF00270.29 OAJ22983.1 - 1.4e-19 70.5 0.0 2.1e-16 60.2 0.0 3.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ22983.1 - 0.0002 21.6 1.7 0.0051 17.1 1.7 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ22983.1 - 0.00056 20.0 0.0 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BORG_CEP PF14957.6 OAJ22983.1 - 0.67 11.1 7.7 1.1 10.4 3.5 2.6 2 0 0 2 2 2 0 Cdc42 effector PAP_assoc PF03828.19 OAJ22984.1 - 4.7e-14 52.3 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAJ22984.1 - 6.7e-10 39.1 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_C93 PF06035.11 OAJ22984.1 - 0.12 12.1 0.4 8.6 6.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial transglutaminase-like cysteine proteinase BTLCP SPT6_acidic PF14632.6 OAJ22984.1 - 6.2 7.5 13.1 0.8 10.3 1.2 3.5 2 1 1 3 3 3 0 Acidic N-terminal SPT6 DEAD PF00270.29 OAJ22985.1 - 5.8e-50 169.5 0.0 3.1e-49 167.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ22985.1 - 5.1e-27 94.4 0.0 4.1e-26 91.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ22985.1 - 0.0034 17.4 0.0 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YqgF PF14639.6 OAJ22985.1 - 0.32 10.8 3.0 9.1 6.1 0.3 3.0 2 1 1 3 3 3 0 Holliday-junction resolvase-like of SPT6 zf-CCHC PF00098.23 OAJ22986.1 - 0.0018 18.2 5.6 0.0033 17.4 5.6 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.14 OAJ22987.1 - 4.8e-66 222.9 0.0 7e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ22987.1 - 6.8e-20 71.4 0.1 1.8e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ22987.1 - 2.9e-07 30.2 0.0 6.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ22987.1 - 1.9e-05 24.3 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 OAJ22988.1 - 2.7e-30 103.9 19.0 2.4e-05 25.0 0.0 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.12 OAJ22988.1 - 1.8e-17 63.6 0.0 4.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAJ22988.1 - 1.4e-12 47.7 0.0 0.96 9.8 0.0 8.1 2 2 6 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ22988.1 - 0.00026 19.8 0.0 0.23 10.1 0.0 3.6 2 2 2 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OAJ22988.1 - 0.0018 17.9 0.4 0.06 12.9 0.1 3.0 2 1 1 3 3 3 1 PQQ-like domain DUF1513 PF07433.11 OAJ22988.1 - 0.0055 15.8 0.2 0.36 9.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 OAJ22988.1 - 0.0093 14.5 0.0 1.7 7.1 0.0 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OAJ22988.1 - 0.012 14.5 1.8 30 3.4 0.1 4.6 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 OAJ22988.1 - 0.016 14.9 0.0 0.086 12.6 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ PF01011.21 OAJ22988.1 - 0.022 14.7 0.1 2.6 8.1 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat PD40 PF07676.12 OAJ22988.1 - 0.38 10.8 3.9 32 4.6 0.0 5.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 OAJ22988.1 - 0.66 10.5 5.6 61 4.3 0.1 5.1 3 1 1 4 4 4 0 PQQ-like domain Baculo_PEP_C PF04513.12 OAJ22993.1 - 2.2 8.3 6.4 1.8 8.6 1.0 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aminotran_3 PF00202.21 OAJ22994.1 - 4.6e-108 361.5 0.1 5.6e-108 361.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAJ22994.1 - 2.7e-05 23.5 0.0 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Neisseria_PilC PF05567.11 OAJ22994.1 - 0.058 12.4 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain POP1 PF06978.11 OAJ22995.1 - 1.6e-23 83.8 17.9 1.6e-23 83.8 17.9 4.0 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAJ22995.1 - 1.5e-14 54.1 0.0 1.5e-14 54.1 0.0 2.8 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T_C PF08669.11 OAJ22995.1 - 0.05 13.5 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain PPP4R2 PF09184.11 OAJ22995.1 - 7.6 6.0 9.2 10 5.6 5.9 2.4 2 0 0 2 2 2 0 PPP4R2 NADH-u_ox-rdase PF10785.9 OAJ22996.1 - 3.3e-31 107.8 0.0 5.1e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 OAJ22996.1 - 4.6e-11 42.5 0.0 7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Acyl_transf_3 PF01757.22 OAJ22996.1 - 0.0078 15.3 0.6 0.01 14.9 0.6 1.1 1 0 0 1 1 1 1 Acyltransferase family TPR_1 PF00515.28 OAJ22997.1 - 1.4e-09 37.3 18.0 0.32 10.9 0.0 8.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ22997.1 - 1.3e-06 28.1 30.3 0.1 12.8 0.2 10.1 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ22997.1 - 3e-06 27.2 3.1 3.4 8.3 0.2 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ22997.1 - 0.00084 19.0 12.5 5.4 6.8 0.0 7.4 9 0 0 9 9 9 2 TPR repeat TPR_8 PF13181.6 OAJ22997.1 - 0.0019 18.2 17.8 1.6 9.1 0.0 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ22997.1 - 0.033 14.8 0.2 0.033 14.8 0.2 9.9 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ22997.1 - 0.048 14.5 0.6 0.048 14.5 0.6 11.4 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ22997.1 - 0.19 12.2 43.6 0.76 10.3 0.0 9.6 8 2 1 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ22997.1 - 0.55 10.6 0.0 0.55 10.6 0.0 8.6 11 0 0 11 11 11 0 Tetratricopeptide repeat Roughex PF06020.11 OAJ22998.1 - 4.8 6.2 4.9 7.5 5.5 4.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein ubiquitin PF00240.23 OAJ22999.1 - 1e-33 114.9 0.7 1e-33 114.9 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAJ22999.1 - 3.3e-26 91.2 0.9 3.3e-26 91.2 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAJ22999.1 - 4.5e-16 58.4 0.8 8e-16 57.6 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ22999.1 - 6.2e-06 26.6 0.4 0.00014 22.3 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ22999.1 - 0.00057 20.0 0.7 0.0013 18.8 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAJ22999.1 - 0.0064 16.4 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ22999.1 - 0.0074 16.6 0.7 0.013 15.8 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 OAJ22999.1 - 0.0098 16.4 1.1 0.014 15.9 1.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.21 OAJ22999.1 - 0.01 16.1 0.2 0.018 15.3 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 OAJ22999.1 - 0.022 14.8 1.1 6.4 6.9 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Chorein_N PF12624.7 OAJ23000.1 - 0.26 11.4 2.5 47 4.1 0.0 3.3 1 1 3 4 4 4 0 N-terminal region of Chorein or VPS13 NOA36 PF06524.12 OAJ23000.1 - 0.4 9.9 1.3 0.66 9.2 1.3 1.2 1 0 0 1 1 1 0 NOA36 protein Cornifin PF02389.15 OAJ23000.1 - 5.5 7.2 16.8 0.038 14.2 6.9 2.5 2 1 1 3 3 3 0 Cornifin (SPRR) family efThoc1 PF11957.8 OAJ23001.1 - 5.2e-58 196.9 0.9 6.1e-29 101.0 0.0 4.6 3 1 0 3 3 3 3 THO complex subunit 1 transcription elongation factor Ribosomal_60s PF00428.19 OAJ23001.1 - 0.01 16.4 8.6 0.01 16.4 8.6 6.7 6 2 2 8 8 8 0 60s Acidic ribosomal protein RRM_1 PF00076.22 OAJ23002.1 - 1.1e-15 57.1 0.1 1.9e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ23002.1 - 0.0046 17.0 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RT_RNaseH PF17917.1 OAJ23003.1 - 2.8e-10 40.4 0.0 4.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ23003.1 - 4.8e-05 23.3 0.0 8.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribonuc_P_40 PF08584.11 OAJ23004.1 - 3.2e-42 144.8 0.0 8.4e-25 87.6 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit CDC45 PF02724.14 OAJ23004.1 - 0.15 10.3 6.2 0.22 9.8 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.8 OAJ23004.1 - 0.34 10.3 3.2 0.63 9.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nop14 PF04147.12 OAJ23004.1 - 1.2 7.3 7.3 1.7 6.8 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 OAJ23004.1 - 1.8 7.6 6.9 3.1 6.8 6.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CDC27 PF09507.10 OAJ23004.1 - 2.3 7.5 10.4 3.8 6.8 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2_4 PF13894.6 OAJ23006.1 - 0.011 16.5 9.2 2.5 9.2 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAJ23006.1 - 0.02 15.0 8.0 0.74 9.9 0.0 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 OAJ23006.1 - 0.027 15.1 0.1 0.079 13.6 0.0 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain SSP160 PF06933.11 OAJ23006.1 - 0.15 10.3 3.3 0.17 10.1 3.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2 PF00096.26 OAJ23006.1 - 0.58 10.7 10.8 3 8.5 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Retrotran_gag_2 PF14223.6 OAJ23007.1 - 4.6e-11 42.5 0.2 8.5e-11 41.7 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ23007.1 - 1.6e-05 24.4 0.1 3.1e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 OAJ23007.1 - 0.00077 19.4 4.5 0.002 18.1 4.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ23007.1 - 0.031 14.1 2.1 0.081 12.8 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_3 PF14244.6 OAJ23007.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type eIF3g PF12353.8 OAJ23007.1 - 2.1 8.8 5.5 2.6 8.5 1.5 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G UQ_con PF00179.26 OAJ23008.1 - 1.7e-16 60.1 0.0 1.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAJ23008.1 - 0.024 14.9 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain DNA_pol_B PF00136.21 OAJ23009.1 - 6.3e-115 384.5 0.0 8.5e-115 384.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OAJ23009.1 - 1.7e-54 184.4 0.0 2.9e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAJ23009.1 - 1.3e-32 113.3 0.0 3.7e-32 111.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAJ23009.1 - 7.8e-23 80.3 3.3 2e-22 79.0 3.3 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF3246 PF11596.8 OAJ23009.1 - 3.3 7.1 6.6 8.4 5.8 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) BAR PF03114.18 OAJ23010.1 - 4e-41 141.2 0.8 6.4e-41 140.6 0.8 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 OAJ23010.1 - 3e-16 58.7 0.0 5.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ23010.1 - 4.2e-11 42.5 0.0 7.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ23010.1 - 2.4e-10 39.9 0.0 5.9e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain Auxin_resp PF06507.13 OAJ23010.1 - 0.088 13.1 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Auxin response factor DUF3104 PF11302.8 OAJ23010.1 - 0.2 11.4 0.1 0.43 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Spt20 PF12090.8 OAJ23010.1 - 1.7 8.2 8.8 0.43 10.2 5.4 1.7 2 0 0 2 2 2 0 Spt20 family FAM76 PF16046.5 OAJ23010.1 - 4.2 6.6 7.3 8.4 5.6 0.4 2.1 2 0 0 2 2 2 0 FAM76 protein F-box-like PF12937.7 OAJ23011.1 - 0.026 14.4 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 0 F-box-like Dimer_Tnp_hAT PF05699.14 OAJ23018.1 - 1.4e-09 37.6 0.0 3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3727 PF12527.8 OAJ23018.1 - 0.057 13.7 2.0 0.15 12.3 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) Chs7 PF12271.8 OAJ23020.1 - 1.7e-18 67.0 1.0 1.9e-08 34.1 0.1 2.1 2 0 0 2 2 2 2 Chitin synthase export chaperone DNA_pol_E_B PF04042.16 OAJ23021.1 - 6.3e-39 133.5 0.0 1.3e-38 132.4 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAJ23021.1 - 2.3e-38 131.3 0.0 3.7e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF4611 PF15387.6 OAJ23021.1 - 6.5 7.1 14.5 0.36 11.1 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sugar_tr PF00083.24 OAJ23022.1 - 3.1e-122 408.7 21.2 3.6e-122 408.5 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ23022.1 - 2.8e-21 75.8 40.9 8.9e-20 70.9 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 OAJ23022.1 - 1.8 8.4 5.1 2.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_45 PF02015.16 OAJ23023.1 - 4.9e-51 173.7 8.5 5.7e-51 173.4 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.16 OAJ23024.1 - 2.2e-24 86.6 0.3 3e-24 86.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.14 OAJ23024.1 - 0.46 9.9 9.9 0.66 9.3 9.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SIR2 PF02146.17 OAJ23025.1 - 3e-05 24.0 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family ATP-synt_ab_N PF02874.23 OAJ23025.1 - 9.6e-05 22.8 0.5 0.00017 22.0 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RVT_2 PF07727.14 OAJ23026.1 - 2.2e-59 201.1 0.0 3.1e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ23026.1 - 0.018 14.8 0.5 0.053 13.3 0.5 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like MFS_1 PF07690.16 OAJ23027.1 - 6.7e-46 156.8 46.8 6.7e-46 156.8 46.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Septin PF00735.18 OAJ23028.1 - 1.3e-121 405.2 0.1 2.5e-121 404.3 0.1 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ23028.1 - 5e-08 33.0 0.1 1.8e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ23028.1 - 9e-06 25.7 4.9 4e-05 23.6 0.1 2.8 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ23028.1 - 6.5e-05 22.5 2.9 0.00055 19.5 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 OAJ23028.1 - 0.00036 20.1 0.3 0.004 16.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 OAJ23028.1 - 0.002 18.4 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ23028.1 - 0.0021 18.5 0.1 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 OAJ23028.1 - 0.0022 17.3 1.4 0.0047 16.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 OAJ23028.1 - 0.0057 17.2 7.5 1.1 9.7 7.5 2.6 1 1 0 1 1 1 1 ABC transporter baeRF_family3 PF18845.1 OAJ23028.1 - 0.0069 16.7 2.8 0.015 15.6 2.8 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 Dynamin_N PF00350.23 OAJ23028.1 - 0.0099 16.0 6.9 0.082 13.0 0.0 3.4 2 2 0 3 3 3 1 Dynamin family Roc PF08477.13 OAJ23028.1 - 0.01 16.0 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ23028.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAJ23028.1 - 0.036 14.4 0.1 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAJ23028.1 - 0.048 12.8 1.3 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 OAJ23028.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAJ23028.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 OAJ23028.1 - 0.53 10.7 10.8 57 4.1 10.8 2.2 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 OAJ23028.1 - 0.73 9.3 7.0 1.2 8.6 7.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 OAJ23028.1 - 1.7 8.4 5.3 24 4.6 0.0 3.5 3 2 0 3 3 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.11 OAJ23028.1 - 5.7 7.1 9.5 0.48 10.5 0.6 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Vps26 PF03643.15 OAJ23029.1 - 6.1e-130 432.2 3.6 7e-130 432.0 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 COX16 PF14138.6 OAJ23031.1 - 8e-27 93.6 0.1 1.6e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.13 OAJ23031.1 - 1.1e-23 83.6 0.0 2.6e-23 82.4 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family KH_1 PF00013.29 OAJ23032.1 - 1.2e-46 156.3 9.3 2e-17 62.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAJ23032.1 - 1.7e-15 56.6 5.3 3.2e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAJ23032.1 - 8.2e-06 25.6 1.5 1 9.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAJ23032.1 - 0.0095 16.0 8.0 0.42 10.7 0.2 3.6 3 1 0 3 3 3 2 NusA-like KH domain zf-CHY PF05495.12 OAJ23033.1 - 5.6e-13 49.2 12.0 1.3e-12 48.0 12.0 1.6 1 1 0 1 1 1 1 CHY zinc finger HypA PF01155.19 OAJ23033.1 - 0.061 13.4 1.4 0.061 13.4 1.4 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cys_rich_KTR PF14205.6 OAJ23033.1 - 0.12 12.1 4.1 0.11 12.3 1.1 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR SP2 PF03014.14 OAJ23033.1 - 0.3 9.5 0.9 0.36 9.2 0.9 1.1 1 0 0 1 1 1 0 Structural protein 2 Elf1 PF05129.13 OAJ23033.1 - 0.54 10.4 9.5 0.11 12.6 5.8 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 OAJ23033.1 - 1.1 9.5 11.2 0.13 12.4 1.3 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Sugar_tr PF00083.24 OAJ23034.1 - 2.4e-88 297.0 16.7 2e-72 244.5 3.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ23034.1 - 1e-21 77.3 15.8 1e-21 77.3 15.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3809 PF12723.7 OAJ23034.1 - 0.018 15.4 0.2 0.035 14.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) RRM_1 PF00076.22 OAJ23038.1 - 5.1e-44 148.0 0.0 2.9e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ23038.1 - 3.2e-09 36.8 0.0 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OAJ23038.1 - 1.1e-05 25.0 0.0 0.0017 18.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ23038.1 - 1.9e-05 24.4 0.0 0.0087 15.9 0.0 2.6 2 1 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAJ23038.1 - 5e-05 23.3 0.0 0.44 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ23038.1 - 0.00026 20.9 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 OAJ23038.1 - 0.17 11.6 0.0 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SNAP PF14938.6 OAJ23039.1 - 2.2e-94 316.0 12.4 2.5e-94 315.9 12.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 OAJ23039.1 - 0.0032 17.6 1.6 4.4 7.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ23039.1 - 0.0055 17.3 19.2 12 6.8 0.2 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ23039.1 - 0.0074 16.9 2.5 0.0074 16.9 2.5 5.4 2 1 4 6 6 6 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 OAJ23039.1 - 0.015 14.4 3.4 0.31 10.1 0.6 2.2 1 1 0 2 2 2 0 Spatacsin C-terminus PerC PF06069.11 OAJ23039.1 - 0.033 14.5 0.7 2.2 8.6 0.1 2.6 2 1 1 3 3 3 0 PerC transcriptional activator DUF4170 PF13773.6 OAJ23039.1 - 0.25 11.5 0.0 0.25 11.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) TPR_2 PF07719.17 OAJ23039.1 - 0.57 10.4 20.4 7.4 7.0 0.1 7.0 3 3 6 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ23039.1 - 2.1 8.3 17.6 4.2 7.4 0.1 6.7 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ23039.1 - 6.7 7.2 10.8 28 5.3 0.1 5.7 4 2 3 8 8 8 0 Tetratricopeptide repeat Bud13 PF09736.9 OAJ23040.1 - 8.1e-47 159.3 5.5 8.1e-47 159.3 5.5 2.6 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF4618 PF15397.6 OAJ23040.1 - 0.021 14.3 2.0 0.028 13.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) eIF-3_zeta PF05091.12 OAJ23040.1 - 0.23 10.4 5.2 0.33 9.9 5.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3350 PF11830.8 OAJ23040.1 - 0.28 11.5 6.2 8.9 6.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3350) RRM_1 PF00076.22 OAJ23041.1 - 2.1e-46 155.6 0.0 3.9e-22 77.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ23041.1 - 1.2e-08 34.6 0.0 0.0016 18.0 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ23041.1 - 1.7e-08 34.4 0.0 0.0035 17.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OAJ23041.1 - 1.4e-06 28.3 2.7 0.022 14.8 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 OAJ23041.1 - 0.00017 21.4 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAJ23041.1 - 0.0019 18.2 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif 4HBT_3 PF13622.6 OAJ23042.1 - 1.2e-29 104.3 1.0 3.9e-29 102.6 1.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily FAD_binding_4 PF01565.23 OAJ23043.1 - 7.4e-26 90.5 4.1 1.5e-25 89.5 2.7 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ23043.1 - 2.6e-06 27.4 0.2 4.6e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like SprB PF13573.6 OAJ23043.1 - 0.09 12.6 1.5 0.81 9.5 0.1 3.2 3 0 0 3 3 3 0 SprB repeat DUF1829 PF08862.10 OAJ23043.1 - 0.16 12.5 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1829 XPG_I_2 PF12813.7 OAJ23045.1 - 7.7e-06 25.6 0.1 0.0021 17.6 0.0 3.1 3 0 0 3 3 3 1 XPG domain containing XPG_N PF00752.17 OAJ23045.1 - 0.0071 16.8 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain K_channel_TID PF07941.11 OAJ23045.1 - 2 8.9 8.4 7 7.2 8.4 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain NTPase_P4 PF11602.8 OAJ23047.1 - 0.15 11.2 1.1 0.17 11.1 1.1 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Pkinase PF00069.25 OAJ23048.1 - 5.3e-70 235.8 0.0 7.6e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23048.1 - 4.6e-35 121.1 0.0 8.3e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 OAJ23048.1 - 4.8e-06 26.3 0.0 0.00039 20.1 0.0 2.5 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 OAJ23048.1 - 0.00061 19.2 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ23048.1 - 0.0048 16.8 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ23048.1 - 0.0096 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ23048.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAJ23048.1 - 0.04 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Asp PF00026.23 OAJ23049.1 - 2.6e-27 96.1 0.0 4.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 OAJ23049.1 - 6.5e-06 26.7 0.1 0.0024 18.5 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ23049.1 - 0.005 17.4 0.0 0.069 13.7 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tma16 PF11176.8 OAJ23050.1 - 7e-40 136.3 0.0 8.6e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF5436 PF17504.2 OAJ23050.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5436) AIP3 PF03915.13 OAJ23051.1 - 6.7e-121 404.2 0.0 1e-120 403.6 0.0 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1640 PF07798.11 OAJ23051.1 - 0.016 15.3 0.1 0.057 13.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Halo_GVPC PF05465.13 OAJ23051.1 - 0.4 11.0 2.8 0.82 10.0 0.3 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat FliJ PF02050.16 OAJ23051.1 - 0.9 9.8 3.5 7.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Flagellar FliJ protein TFIIA PF03153.13 OAJ23052.1 - 0.021 14.9 31.1 0.052 13.5 31.1 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCP_C_terminal PF04130.13 OAJ23053.1 - 1.5e-42 146.1 0.0 3.1e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAJ23053.1 - 2.7e-09 37.1 0.0 2e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Histone_H2A_C PF16211.5 OAJ23057.1 - 1.4e-10 40.7 0.2 1.4e-10 40.7 0.2 1.5 2 0 0 2 2 2 1 C-terminus of histone H2A Glyco_tranf_2_3 PF13641.6 OAJ23059.1 - 3.7e-14 53.2 0.4 8.8e-10 38.9 0.3 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 OAJ23059.1 - 6.1e-11 41.6 8.7 5.4e-09 35.2 8.2 3.2 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.6 OAJ23059.1 - 1.6e-10 40.7 0.0 3.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 OAJ23059.1 - 2.4e-10 40.7 6.1 2.4e-10 40.7 6.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAJ23059.1 - 0.0019 18.0 0.0 1.1 9.1 0.1 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 SlyX PF04102.12 OAJ23061.1 - 0.11 13.1 3.2 9.2 7.0 0.0 3.2 3 0 0 3 3 3 0 SlyX DUF4218 PF13960.6 OAJ23063.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Glyco_hydro_16 PF00722.21 OAJ23064.1 - 5.1e-13 48.9 1.3 7.7e-13 48.3 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 OrsD PF12013.8 OAJ23065.1 - 1.1e-05 25.8 0.1 1.4e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 OAJ23065.1 - 0.0062 16.1 1.7 0.096 12.3 0.1 2.5 2 1 0 2 2 2 1 Zinc-finger C2H2-type Prefoldin_2 PF01920.20 OAJ23066.1 - 0.13 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit zf-CGNR PF11706.8 OAJ23066.1 - 0.22 11.4 2.5 0.41 10.5 2.5 1.4 1 0 0 1 1 1 0 CGNR zinc finger Transposase_21 PF02992.14 OAJ23067.1 - 1.8e-19 69.9 0.0 3.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 OAJ23067.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) HA2 PF04408.23 OAJ23068.1 - 8e-24 84.0 0.2 1.6e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ23068.1 - 2.5e-18 66.2 0.0 6.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ23068.1 - 2.7e-09 37.4 0.0 5.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ23068.1 - 8.2e-07 29.4 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAJ23068.1 - 3.4e-06 27.0 0.0 7.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAJ23068.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAJ23068.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 OAJ23068.1 - 0.017 15.6 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAJ23068.1 - 0.019 14.6 0.0 0.073 12.7 0.0 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OAJ23068.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ23068.1 - 0.023 14.1 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 OAJ23068.1 - 0.056 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAJ23068.1 - 0.21 12.1 0.0 0.48 10.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MULE PF10551.9 OAJ23069.1 - 0.0017 18.8 0.0 0.0053 17.2 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain DUF4224 PF13986.6 OAJ23069.1 - 0.066 13.1 0.1 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4224) FAR1 PF03101.15 OAJ23069.1 - 0.12 13.0 0.3 0.21 12.3 0.3 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF5071 PF16804.5 OAJ23069.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) F-box PF00646.33 OAJ23070.1 - 1.8e-07 30.8 0.3 3.7e-07 29.9 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ23070.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 OAJ23070.1 - 0.00044 20.1 1.9 0.00064 19.6 0.2 2.2 3 0 0 3 3 3 1 F-box-like PRELI PF04707.14 OAJ23071.1 - 3.9e-32 111.2 0.0 4.1e-24 85.2 0.0 2.0 2 0 0 2 2 2 2 PRELI-like family Clathrin_lg_ch PF01086.17 OAJ23072.1 - 5.5e-38 131.3 17.9 4.3e-37 128.4 17.9 2.1 1 1 0 1 1 1 1 Clathrin light chain UCH PF00443.29 OAJ23073.1 - 2.4e-49 168.2 0.0 3.4e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ23073.1 - 1.5e-21 77.4 0.0 4.3e-20 72.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MAM1 PF10434.9 OAJ23073.1 - 0.094 12.3 0.1 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Monopolin complex protein MAM1 DUF4590 PF15257.6 OAJ23074.1 - 0.016 15.1 1.7 0.02 14.8 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Cid2 PF09774.9 OAJ23075.1 - 5.3e-23 82.2 1.0 5.1e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Caffeine-induced death protein 2 SR-25 PF10500.9 OAJ23076.1 - 0.0095 15.6 9.9 0.013 15.1 9.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Acyl-thio_N PF12590.8 OAJ23076.1 - 0.011 16.3 3.5 0.02 15.5 3.5 1.4 1 0 0 1 1 1 0 Acyl-ATP thioesterase Saccharop_dh_N PF04455.12 OAJ23076.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region TcA_TcB_BD PF18276.1 OAJ23076.1 - 0.13 11.3 0.5 0.16 11.0 0.5 1.1 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Lyase_1 PF00206.20 OAJ23083.1 - 5.1e-22 78.6 0.0 8.5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAJ23083.1 - 3.5e-17 62.7 0.0 9.6e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus RNA_pol_L_2 PF13656.6 OAJ23084.1 - 1.2e-27 95.5 0.0 1.5e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ23084.1 - 1.7e-07 30.5 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.6 OAJ23084.1 - 0.0021 16.1 0.0 0.0024 16.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase MFS_1 PF07690.16 OAJ23086.1 - 4.3e-28 98.2 28.0 1.6e-27 96.4 27.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Med13_C PF06333.12 OAJ23087.1 - 2.1e-20 73.2 4.3 2.1e-20 73.2 4.3 3.7 4 1 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain G-patch_2 PF12656.7 OAJ23088.1 - 3.7e-22 78.2 1.3 3.7e-22 78.2 1.3 2.7 3 0 0 3 3 3 1 G-patch domain G-patch PF01585.23 OAJ23088.1 - 7.1e-06 25.8 3.7 1.5e-05 24.8 3.7 1.5 1 0 0 1 1 1 1 G-patch domain CAS_CSE1 PF03378.15 OAJ23089.1 - 8.2e-126 420.1 0.0 1.3e-125 419.4 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAJ23089.1 - 1.3e-117 392.7 0.0 2.2e-117 392.0 0.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAJ23089.1 - 1.3e-09 37.8 0.2 5.1e-07 29.5 0.2 3.7 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 OAJ23089.1 - 0.91 10.0 2.8 18 5.9 0.1 4.1 4 0 0 4 4 4 0 HEAT repeat CH PF00307.31 OAJ23090.1 - 1.5e-46 157.1 0.1 6e-24 84.3 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OAJ23090.1 - 6.3e-19 67.8 0.0 1.8e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OAJ23090.1 - 1.2e-11 44.3 0.1 3.6e-07 29.9 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 OAJ23090.1 - 0.12 12.4 0.0 0.75 9.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain DUF1664 PF07889.12 OAJ23090.1 - 0.15 12.1 0.4 0.35 10.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAJ23090.1 - 0.17 10.8 3.7 0.26 10.1 3.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 OAJ23090.1 - 0.2 11.2 5.2 0.37 10.3 5.2 1.4 1 0 0 1 1 1 0 PspA/IM30 family Spectrin PF00435.21 OAJ23090.1 - 0.54 10.8 5.0 2.8 8.5 0.7 3.1 2 1 0 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 OAJ23090.1 - 0.72 9.9 3.7 0.98 9.5 2.0 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 OAJ23090.1 - 0.93 10.1 4.2 0.58 10.8 1.5 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Redoxin PF08534.10 OAJ23091.1 - 4.2e-29 101.1 0.1 4.9e-29 100.9 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ23091.1 - 1.1e-11 44.7 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family M20_dimer PF07687.14 OAJ23094.1 - 1.9e-09 37.4 0.0 3.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAJ23094.1 - 2.1e-05 24.3 0.3 4e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 NKWYS PF10364.9 OAJ23094.1 - 0.076 13.1 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein HCNGP PF07818.13 OAJ23095.1 - 8e-22 77.7 0.0 1.5e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.7 OAJ23095.1 - 0.0056 17.3 26.5 0.0056 17.3 26.5 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paramyxo_ncap PF00973.19 OAJ23095.1 - 0.13 11.2 9.0 0.18 10.7 9.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glycos_transf_2 PF00535.26 OAJ23096.1 - 4.5e-31 107.9 0.0 5.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAJ23096.1 - 1.4e-11 44.7 0.0 2.6e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAJ23096.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ23096.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 OAJ23096.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 DUF4799 PF16056.5 OAJ23096.1 - 0.087 12.0 0.4 0.13 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) IMUP PF15761.5 OAJ23097.1 - 0.052 14.2 5.7 0.066 13.9 5.7 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 OAJ23097.1 - 0.08 12.5 8.4 0.1 12.2 8.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hamartin PF04388.12 OAJ23097.1 - 1.1 7.8 5.1 1.2 7.7 5.1 1.0 1 0 0 1 1 1 0 Hamartin protein Med3 PF11593.8 OAJ23097.1 - 3.6 6.7 13.0 4.2 6.5 13.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NST1 PF13945.6 OAJ23102.1 - 2.8e-47 161.3 0.0 2.8e-47 161.3 0.0 9.5 7 2 1 9 9 9 1 Salt tolerance down-regulator Nop14 PF04147.12 OAJ23102.1 - 0.00044 18.6 13.9 0.00044 18.6 13.9 4.8 5 1 1 6 6 6 1 Nop14-like family YL1 PF05764.13 OAJ23102.1 - 0.00076 19.7 18.0 0.00076 19.7 18.0 8.0 6 2 0 6 6 6 1 YL1 nuclear protein Nsp1_C PF05064.13 OAJ23103.1 - 2.2e-21 75.8 0.0 8.2e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Spt20 PF12090.8 OAJ23103.1 - 3.2 7.3 14.2 5.9 6.4 14.2 1.4 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 OAJ23107.1 - 0.0016 16.8 12.1 0.0016 16.8 12.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 OAJ23107.1 - 0.0029 16.1 13.3 0.0027 16.2 13.3 1.2 1 0 0 1 1 1 1 Mpp10 protein PI3K_1B_p101 PF10486.9 OAJ23107.1 - 0.0056 14.5 4.6 0.0057 14.5 4.6 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 OAJ23107.1 - 0.028 13.8 13.7 0.024 14.0 13.7 1.2 1 0 0 1 1 1 0 BUD22 PhnA_Zn_Ribbon PF08274.12 OAJ23107.1 - 0.039 13.9 5.3 0.25 11.3 0.6 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon TMEM51 PF15345.6 OAJ23107.1 - 0.067 13.0 0.4 0.077 12.8 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 XAP5 PF04921.14 OAJ23107.1 - 0.079 12.8 3.9 0.088 12.6 3.9 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Nop14 PF04147.12 OAJ23107.1 - 0.15 10.3 23.1 0.2 9.9 23.1 1.1 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 OAJ23107.1 - 0.25 10.1 1.7 0.28 9.9 1.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 OAJ23107.1 - 0.31 10.0 3.1 0.37 9.7 3.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3c_N PF05470.12 OAJ23107.1 - 0.47 8.7 8.3 0.43 8.8 8.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.17 OAJ23107.1 - 0.53 9.0 0.6 0.53 9.0 0.6 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 OAJ23107.1 - 0.59 10.3 3.4 0.86 9.8 3.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Atrophin-1 PF03154.15 OAJ23107.1 - 0.71 8.1 5.1 0.86 7.8 5.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Zip PF02535.22 OAJ23107.1 - 0.84 8.8 1.5 0.84 8.8 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 OAJ23107.1 - 1.9 7.2 3.9 2.2 7.0 3.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 OAJ23107.1 - 2.5 7.4 24.3 3.6 6.9 24.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 OAJ23107.1 - 3.2 7.5 9.4 0.23 11.2 4.8 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 OAJ23107.1 - 3.2 6.6 18.9 4.1 6.3 18.9 1.1 1 0 0 1 1 1 0 Paf1 Polyoma_lg_T_C PF06431.11 OAJ23107.1 - 3.3 6.5 7.4 4.6 6.0 7.4 1.4 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus RNA_pol_Rpc4 PF05132.14 OAJ23107.1 - 3.4 8.1 6.5 5.3 7.5 6.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sigma70_ner PF04546.13 OAJ23107.1 - 5.9 6.7 21.4 12 5.7 21.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region SAPS PF04499.15 OAJ23107.1 - 7.1 5.3 8.7 9.1 4.9 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.10 OAJ23107.1 - 8.3 5.7 16.4 10 5.4 16.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sporozoite_P67 PF05642.11 OAJ23107.1 - 9.1 4.2 15.6 14 3.6 15.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CAS_CSE1 PF03378.15 OAJ23108.1 - 2.8e-08 32.7 0.3 1.7e-06 26.8 0.0 1.9 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus PTPlike_phytase PF14566.6 OAJ23109.1 - 5.7 7.0 12.6 2.3 8.3 9.3 2.0 1 1 0 1 1 1 0 Inositol hexakisphosphate E1-E2_ATPase PF00122.20 OAJ23113.1 - 1.4e-50 171.3 1.3 7.9e-50 168.9 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ23113.1 - 3e-16 60.4 2.6 1.4e-15 58.1 2.6 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ23113.1 - 2.2e-10 40.1 0.1 8.3e-10 38.2 0.1 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ23113.1 - 0.001 18.9 0.1 0.001 18.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ23113.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) F-box PF00646.33 OAJ23114.1 - 6e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ23114.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box mRNA_cap_enzyme PF01331.19 OAJ23115.1 - 4e-50 170.4 0.4 5.3e-50 170.0 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAJ23115.1 - 9.5e-26 90.6 0.0 1.6e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAJ23115.1 - 1e-07 31.8 0.0 5.7e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain IPK PF03770.16 OAJ23117.1 - 3.9e-52 177.0 0.0 1.3e-51 175.3 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase TFIIA PF03153.13 OAJ23117.1 - 0.0008 19.5 23.0 0.0008 19.5 23.0 3.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 OAJ23117.1 - 0.055 14.0 6.4 0.28 11.8 6.4 2.2 1 0 0 1 1 1 0 TCP family transcription factor ROQ_II PF18386.1 OAJ23118.1 - 0.056 13.3 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Roquin II domain Pkinase PF00069.25 OAJ23120.1 - 1.9e-61 207.7 0.0 2.5e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23120.1 - 2.5e-39 135.1 0.0 3.3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ23120.1 - 3.3e-06 26.6 0.0 5.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Dicty_REP PF05086.12 OAJ23121.1 - 1.1 7.2 9.1 2.2 6.2 9.1 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chitin_synth_1 PF01644.17 OAJ23123.1 - 5e-78 260.7 0.0 9.6e-78 259.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ23123.1 - 6.7e-27 93.2 0.0 1.5e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ23123.1 - 3e-22 79.0 6.1 1.1e-16 60.5 0.0 2.6 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ23123.1 - 4.4e-05 23.5 6.2 0.00018 21.5 6.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 LRR19-TM PF15176.6 OAJ23123.1 - 0.013 15.4 0.2 0.055 13.5 0.2 2.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Spt20 PF12090.8 OAJ23123.1 - 8.4 5.9 14.9 14 5.2 14.9 1.2 1 0 0 1 1 1 0 Spt20 family PGM_PMM_I PF02878.16 OAJ23124.1 - 2.2e-36 124.6 0.1 3.4e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAJ23124.1 - 5.7e-28 97.4 0.0 1.6e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAJ23124.1 - 1.4e-14 54.5 0.0 4.6e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAJ23124.1 - 3.3e-06 27.2 0.0 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MPC PF03650.13 OAJ23128.1 - 9.8e-42 141.6 0.3 1.2e-41 141.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ILVD_EDD PF00920.21 OAJ23129.1 - 8.7e-200 664.7 0.0 1e-199 664.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.7 OAJ23130.1 - 5.1e-08 33.8 0.3 8.9e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ23130.1 - 7.9e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ23130.1 - 6.4e-07 29.3 0.1 1.1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L16 PF00252.18 OAJ23132.1 - 1.5e-17 63.8 0.4 1.7e-15 57.2 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L16p/L10e TFIIF_beta_N PF17683.1 OAJ23134.1 - 2.8e-14 53.9 0.0 4.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Serglycin PF04360.12 OAJ23134.1 - 0.74 9.8 2.7 2.7 7.9 0.3 2.3 2 1 0 2 2 2 0 Serglycin V-SNARE_C PF12352.8 OAJ23135.1 - 0.11 12.8 0.3 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus RNA_pol_I_A49 PF06870.12 OAJ23136.1 - 5.4e-78 262.5 0.0 8.4e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Chitin_synth_1 PF01644.17 OAJ23137.1 - 3.2e-36 124.8 0.0 3.5e-32 111.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.15 OAJ23137.1 - 2.1e-11 43.2 0.0 3.6e-06 25.9 0.0 2.9 3 1 1 4 4 4 2 Chitin synthase Chitin_synth_1N PF08407.11 OAJ23137.1 - 3.7e-10 39.6 0.0 1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal DLIC PF05783.11 OAJ23138.1 - 1.5e-41 142.8 18.8 4.2e-27 95.1 0.0 6.9 5 2 0 6 6 6 5 Dynein light intermediate chain (DLIC) MCM PF00493.23 OAJ23138.1 - 9.6e-05 21.6 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 OAJ23138.1 - 0.00048 20.5 0.5 0.0045 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 OAJ23138.1 - 0.0089 15.6 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ23138.1 - 0.067 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OAJ23138.1 - 0.068 13.4 0.6 0.16 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ23138.1 - 0.091 12.5 0.1 0.28 11.0 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPR_2 PF13041.6 OAJ23139.1 - 8.1e-27 93.2 0.0 2.2e-06 27.7 0.0 9.0 8 1 1 9 9 9 4 PPR repeat family PPR PF01535.20 OAJ23139.1 - 8e-21 72.8 7.8 0.028 14.7 0.0 11.5 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 OAJ23139.1 - 5.3e-11 42.4 0.0 0.0029 17.6 0.0 6.1 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAJ23139.1 - 2.5e-10 39.9 0.0 14 5.5 0.0 8.9 11 0 0 11 11 11 2 PPR repeat PPR_long PF17177.4 OAJ23139.1 - 6.2e-06 25.7 1.8 0.0015 17.9 0.1 3.6 2 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OAJ23139.1 - 0.21 12.5 0.1 0.21 12.5 0.1 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ23139.1 - 0.58 10.7 0.0 0.58 10.7 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ23139.1 - 9.3 6.6 12.0 11 6.5 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 OAJ23140.1 - 0.12 11.2 0.7 0.24 10.2 0.7 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain Phage_integrase PF00589.22 OAJ23141.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family SAVED PF18145.1 OAJ23141.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain tRNA-synt_1 PF00133.22 OAJ23142.1 - 1.2e-213 710.7 0.0 2.6e-212 706.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ23142.1 - 5.3e-35 120.6 0.2 1.1e-34 119.6 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ23142.1 - 7.3e-16 57.9 0.4 1.1e-08 34.3 0.2 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAJ23142.1 - 2.8e-07 30.2 5.8 8.7e-06 25.4 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAJ23142.1 - 0.00056 19.3 0.0 0.54 9.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 OAJ23142.1 - 0.12 11.3 0.3 1.5 7.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Sugar_tr PF00083.24 OAJ23143.1 - 1e-121 407.0 28.7 1.2e-121 406.8 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ23143.1 - 4.2e-20 72.0 46.1 7.6e-18 64.5 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TFIID-31kDa PF02291.15 OAJ23144.1 - 1.7e-45 154.0 0.0 2.3e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAJ23144.1 - 0.0036 17.3 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated MAD PF05557.13 OAJ23145.1 - 1.6e-42 145.8 57.7 9e-35 120.2 9.7 2.3 2 1 0 2 2 2 2 Mitotic checkpoint protein HALZ PF02183.18 OAJ23145.1 - 1.4e-05 25.2 26.9 0.065 13.5 3.1 6.5 5 1 1 6 6 6 3 Homeobox associated leucine zipper SKA2 PF16740.5 OAJ23145.1 - 0.00018 21.3 3.3 0.00018 21.3 3.3 5.7 6 1 1 7 7 7 2 Spindle and kinetochore-associated protein 2 COG5 PF10392.9 OAJ23145.1 - 0.0047 17.1 5.1 0.0047 17.1 5.1 3.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF5101 PF17031.5 OAJ23145.1 - 0.18 11.9 8.0 1.3 9.2 0.4 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5101) KIAA1430 PF13879.6 OAJ23145.1 - 0.4 11.4 0.0 0.4 11.4 0.0 3.6 4 2 0 4 4 4 0 KIAA1430 homologue KIP1 PF07765.12 OAJ23145.1 - 0.62 10.2 8.1 0.17 12.1 2.5 3.1 3 0 0 3 3 3 0 KIP1-like protein DUF4407 PF14362.6 OAJ23145.1 - 9.7 5.4 62.1 0.059 12.7 2.6 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) RNA_pol_Rpb4 PF03874.16 OAJ23149.1 - 6.3e-12 45.9 0.2 1e-11 45.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 AKAP2_C PF15304.6 OAJ23149.1 - 0.19 11.0 0.9 0.24 10.7 0.9 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus NAD_binding_5 PF07994.12 OAJ23150.1 - 3.7e-141 470.2 0.0 5.2e-141 469.7 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAJ23150.1 - 4.6e-42 142.7 0.1 8.2e-42 141.9 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase WD40 PF00400.32 OAJ23152.1 - 9.6e-24 83.2 17.5 5.5e-07 30.2 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ23152.1 - 3.5e-10 40.0 0.0 0.00029 21.1 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ23152.1 - 0.0026 16.8 0.7 0.16 10.9 0.1 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 OAJ23152.1 - 0.017 13.6 0.6 0.024 13.1 0.6 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family WD40_like PF17005.5 OAJ23152.1 - 0.053 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain eIF2A PF08662.11 OAJ23152.1 - 0.25 11.2 0.2 0.76 9.6 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Fungal_trans PF04082.18 OAJ23153.1 - 2.1e-14 53.2 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ23153.1 - 2.4e-06 27.6 9.7 4.2e-06 26.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cwf_Cwc_15 PF04889.12 OAJ23153.1 - 1.2 8.8 6.0 3.1 7.5 6.0 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Adaptin_binding PF10199.9 OAJ23154.1 - 0.083 13.5 21.6 1.1 9.9 17.6 3.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Velvet PF11754.8 OAJ23155.1 - 4.9e-64 216.7 0.0 8.1e-64 215.9 0.0 1.3 1 1 0 1 1 1 1 Velvet factor DUF5572 PF17733.1 OAJ23156.1 - 6.1e-18 64.4 0.5 1.2e-17 63.5 0.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DEC-1_N PF04625.13 OAJ23156.1 - 0.14 11.1 9.7 0.19 10.7 9.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MRP-S26 PF14943.6 OAJ23157.1 - 2.5 8.0 7.0 0.47 10.3 2.4 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PX PF00787.24 OAJ23158.1 - 2.3e-21 75.9 0.0 2.9e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 PX domain UPF0020 PF01170.18 OAJ23159.1 - 1.8e-11 44.1 0.0 9.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 AviRa PF11599.8 OAJ23159.1 - 0.0032 17.0 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 OAJ23159.1 - 0.005 17.6 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ23159.1 - 0.01 16.5 0.0 0.051 14.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ23159.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ23159.1 - 0.16 11.3 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family zf-CCCH_4 PF18044.1 OAJ23160.1 - 1.7e-06 27.7 3.6 3.1e-06 26.9 3.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ23160.1 - 2e-06 27.7 5.5 3.5e-06 26.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAJ23160.1 - 0.00059 19.7 2.2 0.001 18.9 2.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NupH_GANP PF16768.5 OAJ23160.1 - 0.0085 15.8 24.6 0.0085 15.8 24.6 6.2 1 1 5 6 6 6 3 Nucleoporin homology of Germinal-centre associated nuclear protein Torus PF16131.5 OAJ23160.1 - 0.15 12.8 0.3 0.24 12.1 0.3 1.3 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 OAJ23160.1 - 0.29 11.7 3.5 0.55 10.8 3.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 OAJ23160.1 - 0.54 11.1 170.4 12 6.8 33.5 6.9 1 1 6 7 7 7 0 Nucleoporin FG repeat region APS_kinase PF01583.20 OAJ23161.1 - 1.7e-70 236.0 0.0 2e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAJ23161.1 - 2.2e-06 27.9 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ23161.1 - 0.00045 20.8 0.0 0.00067 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ23161.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 OAJ23161.1 - 0.0073 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ23161.1 - 0.02 15.3 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.12 OAJ23161.1 - 0.042 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Arf PF00025.21 OAJ23161.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Zeta_toxin PF06414.12 OAJ23161.1 - 0.098 11.9 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 OAJ23161.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 OAJ23161.1 - 0.14 12.0 0.0 6.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Ribosomal_L1 PF00687.21 OAJ23162.1 - 1e-42 146.2 0.6 1.2e-42 146.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RL10P_insert PF17777.1 OAJ23163.1 - 3.5e-23 81.4 0.4 9.8e-23 79.9 0.1 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAJ23163.1 - 3.9e-16 59.0 0.0 6.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 PBP1_TM PF14812.6 OAJ23163.1 - 0.14 12.6 5.2 0.3 11.5 5.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAJ23163.1 - 0.26 11.7 9.1 0.47 10.9 9.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAJ23163.1 - 1.9 6.5 5.8 2.8 6.0 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ23163.1 - 2.1 7.6 6.0 3.3 7.0 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein NUC153 PF08159.12 OAJ23165.1 - 6e-11 42.0 0.3 1e-10 41.2 0.3 1.4 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.12 OAJ23165.1 - 0.4 8.8 18.8 0.57 8.3 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 OAJ23165.1 - 4.5 7.1 12.7 7.2 6.5 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ23166.1 - 0.49 10.0 8.1 0.76 9.4 6.2 1.9 2 0 0 2 2 2 0 Spt20 family Spt5_N PF11942.8 OAJ23166.1 - 2.3 9.2 7.2 2.1 9.4 1.8 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DASH_Spc34 PF08657.10 OAJ23166.1 - 2.6 7.8 5.9 17 5.1 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Spc34 DivIC PF04977.15 OAJ23166.1 - 3.5 7.4 9.0 24 4.8 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator Pmp3 PF01679.17 OAJ23167.1 - 2.5e-20 72.4 8.5 2.5e-20 72.4 8.5 1.6 2 0 0 2 2 2 1 Proteolipid membrane potential modulator DUF3446 PF11928.8 OAJ23167.1 - 6.5 7.1 8.6 13 6.2 8.6 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Peptidase_M17 PF00883.21 OAJ23168.1 - 2.7e-112 375.1 0.2 3.6e-112 374.7 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 OAJ23168.1 - 2.9e-08 33.6 0.1 7.1e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain BshC PF10079.9 OAJ23175.1 - 0.019 13.8 0.6 0.024 13.4 0.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Rrn6 PF10214.9 OAJ23175.1 - 0.029 12.9 0.1 0.029 12.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Auts2 PF15336.6 OAJ23175.1 - 0.062 13.4 8.1 0.088 12.9 8.1 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein MCM_bind PF09739.9 OAJ23175.1 - 0.17 10.3 2.1 0.21 10.0 2.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Neur_chan_memb PF02932.16 OAJ23175.1 - 0.17 11.9 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 OAJ23175.1 - 0.23 11.2 0.3 0.27 10.9 0.3 1.2 1 0 0 1 1 1 0 Connexin MotA_ExbB PF01618.16 OAJ23175.1 - 0.26 11.1 1.1 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family CDC45 PF02724.14 OAJ23175.1 - 0.41 8.9 3.6 0.54 8.5 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAJ23175.1 - 0.44 9.2 1.4 0.57 8.9 1.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAJ23175.1 - 0.72 9.6 7.1 0.88 9.3 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tho2 PF11262.8 OAJ23175.1 - 1.1 8.4 4.6 1.4 8.0 4.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3043 PF11241.8 OAJ23175.1 - 3.7 7.6 10.1 5.5 7.0 10.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) NARP1 PF12569.8 OAJ23175.1 - 4.5 6.1 9.9 5.5 5.8 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S8 PF00082.22 OAJ23176.1 - 2.7e-30 105.7 2.0 4.3e-30 105.0 2.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ23176.1 - 2.6e-09 37.8 0.0 6.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAJ23176.1 - 7.3e-05 22.7 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 PA domain ASH PF15780.5 OAJ23176.1 - 0.11 12.8 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MFS_1 PF07690.16 OAJ23177.1 - 2.2e-26 92.6 63.5 5.6e-21 74.8 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ23177.1 - 7.8e-07 28.3 34.9 6.5e-05 22.0 11.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Spt5_N PF11942.8 OAJ23178.1 - 3.8 8.6 17.2 13 6.9 3.4 3.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal TFIIE-A_C PF11521.8 OAJ23178.1 - 9.3 6.6 16.6 5.9 7.3 4.2 3.6 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha SNO PF01174.19 OAJ23179.1 - 1.9e-50 171.3 0.0 1.4e-39 135.9 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAJ23179.1 - 3e-08 33.5 0.0 4.1e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OAJ23179.1 - 0.0019 17.8 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 OAJ23179.1 - 0.051 13.4 0.1 0.082 12.7 0.1 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family KAR9 PF08580.10 OAJ23179.1 - 7.8 4.9 7.8 9.9 4.6 7.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 adh_short PF00106.25 OAJ23180.1 - 1.7e-09 37.5 0.0 3.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ23180.1 - 4.8e-06 26.3 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CMAS PF02353.20 OAJ23181.1 - 7.5e-56 189.4 0.0 1.8e-51 175.0 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ23181.1 - 9.2e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ23181.1 - 7.5e-10 39.3 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ23181.1 - 2.3e-08 34.0 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ23181.1 - 3.8e-08 33.3 0.0 9.5e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ23181.1 - 5.5e-05 23.8 0.0 0.0001 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OAJ23181.1 - 0.0039 17.0 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 OAJ23181.1 - 0.017 16.1 0.0 0.036 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 OAJ23181.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 OAJ23181.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 OAJ23181.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_16 PF10294.9 OAJ23181.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 2 0 0 2 2 2 0 Lysine methyltransferase Stealth_CR2 PF11380.8 OAJ23182.1 - 3e-31 107.8 0.1 5.9e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OAJ23182.1 - 1.5e-09 37.6 0.7 1.5e-09 37.6 0.7 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 OAJ23182.1 - 1.2e-06 28.2 0.0 2.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 MAGI_u5 PF16666.5 OAJ23182.1 - 0.59 10.3 3.5 1.1 9.4 3.5 1.3 1 0 0 1 1 1 0 Unstructured region on MAGI DUF4028 PF13220.6 OAJ23183.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) COesterase PF00135.28 OAJ23184.1 - 2.7e-83 280.6 0.0 3.3e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ23184.1 - 2e-06 27.8 0.4 0.0062 16.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sulfatase PF00884.23 OAJ23185.1 - 6.2e-59 199.9 0.0 8.7e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OAJ23185.1 - 0.0095 14.6 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 OAJ23185.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAJ23185.1 - 0.025 15.3 0.1 1.4 9.7 0.1 2.7 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.18 OAJ23185.1 - 0.061 12.7 0.0 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily Metallophos PF00149.28 OAJ23186.1 - 2.2e-09 38.1 0.3 4.9e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAJ23186.1 - 0.0033 17.6 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain ABC_membrane_2 PF06472.15 OAJ23187.1 - 2.5e-93 312.4 4.6 3.4e-93 311.9 4.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAJ23187.1 - 1.7e-17 64.2 0.0 3.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 OAJ23187.1 - 0.0021 17.8 0.1 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ23187.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 OAJ23187.1 - 0.023 15.1 0.1 0.052 14.0 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ23187.1 - 0.024 15.0 0.0 0.073 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAJ23187.1 - 0.027 14.2 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ23187.1 - 0.029 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OAJ23187.1 - 0.032 14.8 0.0 0.096 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAJ23187.1 - 0.037 14.5 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAJ23187.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ23187.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 OAJ23187.1 - 0.26 8.8 0.0 0.42 8.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rad60-SLD PF11976.8 OAJ23188.1 - 2.4e-11 43.3 0.3 2.4e-11 43.3 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ23188.1 - 1.1e-05 25.1 0.6 1.1e-05 25.1 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin family SPT6_acidic PF14632.6 OAJ23188.1 - 2.2 8.9 16.7 9.2 6.9 1.1 3.7 3 0 0 3 3 3 0 Acidic N-terminal SPT6 DnaJ PF00226.31 OAJ23189.1 - 7.3e-08 32.4 0.0 6.8e-07 29.3 0.0 2.5 1 1 1 2 2 2 1 DnaJ domain DnaJ PF00226.31 OAJ23191.1 - 1.8e-09 37.6 1.5 3e-09 36.9 0.0 2.1 2 1 0 2 2 1 1 DnaJ domain Peptidase_C37 PF05416.12 OAJ23191.1 - 0.00059 18.5 8.0 0.0007 18.2 8.0 1.1 1 0 0 1 1 1 1 Southampton virus-type processing peptidase TFIIA PF03153.13 OAJ23191.1 - 0.05 13.6 24.7 0.058 13.4 24.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRP14 PF15459.6 OAJ23191.1 - 0.056 14.1 2.0 0.056 14.1 2.0 3.1 1 1 2 3 3 2 0 60S ribosome biogenesis protein Rrp14 SpoIIP PF07454.11 OAJ23191.1 - 0.13 11.8 9.9 0.16 11.4 9.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 OAJ23191.1 - 0.16 12.1 8.0 0.2 11.8 8.0 1.3 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 OAJ23191.1 - 0.17 11.0 8.6 0.2 10.8 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OAJ23191.1 - 0.18 11.8 10.6 0.24 11.4 10.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 OAJ23191.1 - 0.35 9.7 11.4 0.49 9.2 11.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 OAJ23191.1 - 0.6 8.4 2.2 0.57 8.5 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UCR_TM PF02921.14 OAJ23191.1 - 0.71 10.4 0.0 0.71 10.4 0.0 2.4 2 1 0 2 2 1 0 Ubiquinol cytochrome reductase transmembrane region MMR1 PF08505.10 OAJ23191.1 - 0.79 10.0 15.3 1 9.6 15.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.14 OAJ23191.1 - 0.9 7.8 21.3 1.1 7.4 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 OAJ23191.1 - 0.97 8.4 14.8 1.2 8.1 14.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 OAJ23191.1 - 1.1 9.2 14.3 1.5 8.8 14.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Asp-B-Hydro_N PF05279.11 OAJ23191.1 - 1.3 9.0 15.5 1.7 8.7 15.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3523 PF12037.8 OAJ23191.1 - 2.9 7.2 35.4 4.5 6.6 35.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF913 PF06025.12 OAJ23191.1 - 2.9 6.8 8.6 4.1 6.3 8.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2370 PF10176.9 OAJ23191.1 - 3 7.4 5.8 4 7.0 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4228 PF14009.6 OAJ23191.1 - 3.8 7.9 11.4 3.6 7.9 10.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF3492 PF11997.8 OAJ23191.1 - 3.9 7.1 8.4 5.9 6.5 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) VIR_N PF15912.5 OAJ23191.1 - 4.7 6.7 12.1 5.8 6.4 12.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1980 PF09323.10 OAJ23191.1 - 5.4 6.9 6.3 8.3 6.3 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) LMBR1 PF04791.16 OAJ23191.1 - 7 5.4 6.1 7.8 5.3 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NPR3 PF03666.13 OAJ23191.1 - 9.2 4.9 20.1 11 4.7 20.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PI3Ka PF00613.20 OAJ23194.1 - 1e-52 178.2 0.0 1.6e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OAJ23194.1 - 3e-47 161.5 0.0 7.2e-33 114.4 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OAJ23194.1 - 1.4e-33 115.7 0.0 2.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 OAJ23194.1 - 0.004 17.4 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.6 OAJ23194.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Transketolase_N PF00456.21 OAJ23196.1 - 9.8e-16 57.6 2.6 3.7e-14 52.4 2.6 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 OAJ23196.1 - 2.5e-11 43.5 0.0 8e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 OAJ23196.1 - 3.1e-05 23.7 0.1 7.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 OAJ23196.1 - 0.0012 19.1 0.1 0.0054 17.0 0.0 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 OAJ23196.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component TMEM214 PF10151.9 OAJ23196.1 - 0.087 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator NUC205 PF08168.11 OAJ23196.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain TPP_enzyme_C PF02775.21 OAJ23196.1 - 0.14 12.0 0.2 0.58 9.9 0.1 2.1 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TFIIA PF03153.13 OAJ23197.1 - 1.7 8.6 37.3 2.4 8.1 37.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP_sp32 PF07222.12 OAJ23197.1 - 5.9 6.3 8.3 9.6 5.6 8.3 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Phage_GPD PF05954.11 OAJ23197.1 - 7.9 5.7 16.3 1.2 8.3 9.8 2.5 2 1 1 3 3 3 0 Phage late control gene D protein (GPD) RasGEF PF00617.19 OAJ23198.1 - 2.8e-40 138.4 0.0 6.7e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ23198.1 - 1.4e-17 63.8 0.0 3.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 OAJ23198.1 - 4e-14 52.0 0.1 8.9e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAJ23198.1 - 1.6e-13 50.3 0.0 3.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ23198.1 - 7.8e-13 47.8 0.0 1.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain RhoGAP PF00620.27 OAJ23198.1 - 0.18 11.6 0.0 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.25 OAJ23201.1 - 4e-20 72.3 0.0 1.1e-19 70.8 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23201.1 - 8.6e-06 25.2 0.0 2.9e-05 23.5 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAJ23201.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ23201.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OAJ23201.1 - 0.097 12.6 0.1 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ACBP PF00887.19 OAJ23202.1 - 3.1e-23 81.8 0.0 4.9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein YL1 PF05764.13 OAJ23202.1 - 0.042 14.0 5.3 0.06 13.5 5.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 OAJ23202.1 - 0.37 10.5 7.6 0.52 10.0 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ23202.1 - 1.1 8.5 8.1 1.7 7.9 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.27 OAJ23203.1 - 1.4e-47 161.7 0.0 2.7e-26 92.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ23203.1 - 1.1e-38 133.5 15.4 2.7e-21 76.5 3.8 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 OAJ23203.1 - 1.5e-11 44.2 0.2 3.1e-05 23.5 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ23203.1 - 2.4e-05 24.3 0.1 0.05 13.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OAJ23203.1 - 4e-05 23.7 2.2 0.054 13.6 0.2 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 OAJ23203.1 - 0.00011 21.8 0.9 0.48 10.2 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ23203.1 - 0.00016 22.0 1.2 0.59 10.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 OAJ23203.1 - 0.00025 21.2 0.6 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAJ23203.1 - 0.00037 20.6 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 OAJ23203.1 - 0.00049 19.7 0.0 0.55 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAJ23203.1 - 0.00072 20.1 0.1 0.14 12.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ23203.1 - 0.0013 18.2 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_15 PF13175.6 OAJ23203.1 - 0.0037 17.0 0.1 0.96 9.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 OAJ23203.1 - 0.0047 17.3 0.3 3.4 8.0 0.1 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAJ23203.1 - 0.005 16.7 2.6 7.8 6.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 OAJ23203.1 - 0.0082 15.9 0.1 0.91 9.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 OAJ23203.1 - 0.015 14.3 0.0 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 OAJ23203.1 - 0.016 14.5 0.2 3.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 OAJ23203.1 - 0.039 14.2 0.1 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 OAJ23203.1 - 0.049 14.2 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAJ23203.1 - 0.05 12.8 0.2 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAJ23203.1 - 0.074 12.8 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ23203.1 - 0.24 11.5 2.1 20 5.3 0.2 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAJ23203.1 - 1.3 9.3 3.3 1.5 9.1 0.0 2.7 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF1097 PF06496.11 OAJ23203.1 - 8 6.6 14.2 0.23 11.6 3.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) KH_1 PF00013.29 OAJ23204.1 - 3.3e-42 142.2 10.4 1.7e-16 59.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAJ23204.1 - 2.2e-09 37.0 9.1 0.0062 16.3 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAJ23204.1 - 2.3e-07 30.6 1.8 0.062 13.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAJ23204.1 - 0.0052 16.8 6.4 0.37 10.9 0.3 3.3 3 0 0 3 3 3 1 NusA-like KH domain Complex1_LYR PF05347.15 OAJ23205.1 - 5e-05 23.3 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ23205.1 - 0.0085 16.8 1.5 0.014 16.1 1.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like TIMELESS PF04821.14 OAJ23206.1 - 6.3e-72 242.2 0.0 6.3e-72 242.2 0.0 2.1 2 0 0 2 2 2 1 Timeless protein NDUF_B12 PF08122.12 OAJ23208.1 - 1.1 9.4 3.2 0.97 9.5 0.2 2.2 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family adh_short_C2 PF13561.6 OAJ23214.1 - 2.7e-43 148.2 0.3 5.9e-43 147.1 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ23214.1 - 5.6e-43 146.7 0.1 8.6e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ23214.1 - 1e-08 35.3 2.1 3.3e-08 33.7 0.5 2.2 3 0 0 3 3 3 1 KR domain Epimerase PF01370.21 OAJ23214.1 - 7.2e-05 22.4 1.7 0.00064 19.3 1.7 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ23214.1 - 0.00033 20.2 0.7 0.0049 16.3 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 OAJ23214.1 - 0.016 14.5 0.4 0.029 13.7 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 OAJ23214.1 - 0.017 15.2 0.2 0.05 13.7 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 OAJ23214.1 - 0.021 14.2 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) YjeF_N PF03853.15 OAJ23214.1 - 0.063 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus MukF_M PF17192.4 OAJ23214.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 MukF middle domain Robl_LC7 PF03259.17 OAJ23215.1 - 5.5e-06 26.1 0.0 8.6e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain Glyco_hydro_18 PF00704.28 OAJ23216.1 - 2.4e-56 191.8 0.4 2.8e-56 191.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2002 PF09400.10 OAJ23216.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) OHCU_decarbox PF09349.10 OAJ23217.1 - 5.3e-22 79.0 0.0 1.3e-21 77.8 0.0 1.6 1 0 0 1 1 1 1 OHCU decarboxylase SCO1-SenC PF02630.14 OAJ23218.1 - 2e-41 141.0 0.0 3.2e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAJ23218.1 - 0.02 14.8 0.0 0.069 13.1 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family HAD_2 PF13419.6 OAJ23219.1 - 4.4e-10 39.9 0.0 1.1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ23219.1 - 2.9e-09 37.6 0.0 8.8e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ23219.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like SKN1 PF03935.15 OAJ23220.1 - 4.3e-154 513.6 0.1 6.3e-154 513.1 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DASH_Ask1 PF08655.10 OAJ23221.1 - 5.9e-28 96.6 0.0 9.3e-28 95.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 PBP1_TM PF14812.6 OAJ23221.1 - 9.1 6.7 11.9 1.4e+02 3.0 0.1 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC4_2 PF13923.6 OAJ23223.1 - 2.5e-10 40.0 10.5 2.5e-10 40.0 10.5 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ23223.1 - 4.2e-09 36.1 6.1 4.2e-09 36.1 6.1 3.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ23223.1 - 6.8e-09 35.6 4.6 6.8e-09 35.6 4.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ23223.1 - 2.2e-08 34.3 9.3 2.2e-08 34.3 9.3 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ23223.1 - 1e-07 31.7 9.0 1e-07 31.7 9.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ23223.1 - 1.1e-06 28.5 6.1 1.1e-06 28.5 6.1 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAJ23223.1 - 2e-05 24.3 1.3 7.6e-05 22.5 1.3 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OAJ23223.1 - 0.00039 20.2 8.7 0.00039 20.2 8.7 2.4 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ23223.1 - 0.00067 19.8 9.4 0.00067 19.8 9.4 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAJ23223.1 - 0.0014 18.8 7.0 0.0055 17.0 7.0 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAJ23223.1 - 0.0062 16.7 6.0 0.0062 16.7 6.0 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 OAJ23223.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 OAJ23223.1 - 0.27 11.1 3.2 0.61 9.9 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OAJ23223.1 - 2.1 8.1 6.0 1.9 8.3 4.2 1.9 2 0 0 2 2 1 0 RING-like zinc finger zf-P11 PF03854.14 OAJ23223.1 - 2.8 7.7 10.8 1.1 9.0 6.2 2.6 2 1 1 3 3 3 0 P-11 zinc finger Ras PF00071.22 OAJ23224.1 - 3.6e-57 192.5 0.1 4.2e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ23224.1 - 6.1e-32 110.4 0.0 9.4e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ23224.1 - 4.4e-14 52.3 0.0 5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ23224.1 - 6.5e-08 32.7 0.0 1.2e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ23224.1 - 1.3e-06 28.1 0.1 4.4e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ23224.1 - 5.5e-06 25.9 0.1 7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAJ23224.1 - 4.5e-05 23.4 0.2 0.0042 17.0 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 OAJ23224.1 - 0.00041 20.2 0.5 0.016 15.0 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OAJ23224.1 - 0.0013 18.5 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OAJ23224.1 - 0.0049 16.2 0.2 0.076 12.3 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.19 OAJ23224.1 - 0.0063 16.1 0.0 0.024 14.2 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAJ23224.1 - 0.0084 16.5 0.1 0.019 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ23224.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ23224.1 - 0.016 15.0 0.0 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 OAJ23224.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OAJ23224.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OAJ23224.1 - 0.036 14.1 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OAJ23224.1 - 0.051 13.5 0.3 0.099 12.5 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 OAJ23224.1 - 0.056 13.7 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 OAJ23224.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OAJ23224.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 OAJ23224.1 - 0.15 11.2 0.2 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MutS_V PF00488.21 OAJ23225.1 - 2.5e-50 171.1 0.0 4e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ23225.1 - 1.8e-07 31.6 0.5 1.8e-07 31.6 0.5 2.8 2 1 1 3 3 3 1 MutS domain III AAA_29 PF13555.6 OAJ23225.1 - 0.025 14.3 0.1 0.082 12.7 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OAJ23225.1 - 0.09 12.4 1.3 0.21 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 OAJ23225.1 - 0.96 9.9 0.0 0.96 9.9 0.0 2.7 4 0 0 4 4 4 0 AAA domain TMEM223 PF14640.6 OAJ23227.1 - 0.01 16.0 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 223 SF1-HH PF16275.5 OAJ23228.1 - 1.1e-38 132.1 1.7 1.8e-38 131.4 1.7 1.3 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 OAJ23228.1 - 8.6e-10 38.2 14.4 8.3e-05 22.5 3.5 2.7 3 0 0 3 3 3 2 Zinc knuckle DUF1897 PF09005.10 OAJ23228.1 - 8.9e-09 34.7 15.5 0.00013 21.4 2.6 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) KH_1 PF00013.29 OAJ23228.1 - 2.1e-08 33.9 0.1 3.9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 OAJ23228.1 - 4.8e-07 29.6 10.3 0.00016 21.5 3.5 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ23228.1 - 0.33 10.8 14.9 0.45 10.4 5.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ23228.1 - 3.8 7.3 7.5 6.2 6.6 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Tnp_zf-ribbon_2 PF13842.6 OAJ23228.1 - 6.6 7.6 6.9 14 6.6 6.9 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Zn_clus PF00172.18 OAJ23229.1 - 1.5e-06 28.2 9.6 2.5e-06 27.5 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2781 PF10914.8 OAJ23230.1 - 1.9e-34 119.2 7.0 2.2e-34 119.0 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Asp PF00026.23 OAJ23231.1 - 4.5e-15 55.9 0.0 1.4e-11 44.4 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ23231.1 - 0.02 15.1 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal BING4CT PF08149.11 OAJ23236.1 - 1.4e-36 124.1 0.0 3e-34 116.7 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 OAJ23236.1 - 0.00034 19.8 0.0 0.00051 19.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OAJ23236.1 - 0.00083 20.1 0.3 0.084 13.8 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ23236.1 - 0.0099 16.2 0.1 4.1 7.8 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4665 PF15679.5 OAJ23236.1 - 1.9 9.1 6.1 0.21 12.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Arm PF00514.23 OAJ23237.1 - 2.2e-96 313.3 12.4 2.6e-13 49.5 0.1 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAJ23237.1 - 2.2e-23 82.5 3.6 4.7e-23 81.4 3.6 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 OAJ23237.1 - 3.8e-23 81.7 0.2 1.7e-05 25.1 0.0 6.8 3 1 6 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 OAJ23237.1 - 1.9e-22 79.3 4.7 2.8e-08 34.1 0.0 6.7 5 1 2 7 7 7 6 HEAT-like repeat Arm_3 PF16186.5 OAJ23237.1 - 6.5e-19 67.2 0.1 2e-18 65.7 0.1 1.9 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 OAJ23237.1 - 3.5e-17 61.0 2.6 0.00062 19.8 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 OAJ23237.1 - 9.9e-05 22.7 2.7 0.062 14.0 0.0 5.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Arm_2 PF04826.13 OAJ23237.1 - 0.0003 20.3 0.0 0.91 8.9 0.0 3.8 2 1 2 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.8 OAJ23237.1 - 0.00061 19.9 0.4 0.25 11.5 0.0 4.1 3 2 1 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.20 OAJ23237.1 - 0.0033 16.1 0.0 0.034 12.7 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 OAJ23237.1 - 0.0064 16.7 3.2 1.9 8.8 0.1 4.2 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 ABC_tran PF00005.27 OAJ23239.1 - 5.2e-47 159.8 0.2 5.1e-23 82.1 0.0 2.9 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAJ23239.1 - 1.4e-20 73.1 4.0 1.4e-20 73.1 4.0 2.3 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 OAJ23239.1 - 6.5e-16 59.0 8.2 0.002 18.0 0.1 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ23239.1 - 2.4e-09 38.0 7.2 0.0023 18.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.19 OAJ23239.1 - 1.1e-08 34.8 2.2 0.31 10.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ23239.1 - 1.9e-08 33.9 0.3 0.0054 16.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ23239.1 - 5.6e-07 29.6 4.2 0.0055 16.5 0.0 4.2 2 2 1 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ23239.1 - 9.8e-06 25.6 1.9 0.0085 16.2 0.2 3.3 4 0 0 4 4 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ23239.1 - 2.6e-05 24.7 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 OAJ23239.1 - 9.8e-05 22.7 0.0 0.27 11.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 OAJ23239.1 - 0.00027 20.7 0.7 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 OAJ23239.1 - 0.00058 20.2 0.5 0.84 9.9 0.0 3.1 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 OAJ23239.1 - 0.00091 19.2 0.5 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 OAJ23239.1 - 0.0011 18.8 4.6 0.095 12.6 0.1 3.5 4 0 0 4 4 4 1 RsgA GTPase MeaB PF03308.16 OAJ23239.1 - 0.002 17.1 0.1 0.42 9.6 0.0 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAJ23239.1 - 0.004 17.7 0.0 6.1 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ23239.1 - 0.0041 17.3 0.4 6.1 7.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.22 OAJ23239.1 - 0.0042 16.3 0.1 4.4 6.4 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain T2SSE PF00437.20 OAJ23239.1 - 0.0044 16.1 0.1 0.56 9.2 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.14 OAJ23239.1 - 0.0054 16.6 0.8 5.4 6.9 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 OAJ23239.1 - 0.0068 16.8 0.4 1.7 9.1 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAJ23239.1 - 0.014 15.8 1.1 9.1 6.7 0.1 3.1 3 0 0 3 3 3 0 RNA helicase FeoB_N PF02421.18 OAJ23239.1 - 0.016 14.7 0.0 0.57 9.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 OAJ23239.1 - 0.017 15.4 0.0 3.8 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OAJ23239.1 - 0.018 14.4 0.2 1.8 7.8 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 OAJ23239.1 - 0.021 14.6 4.1 1.1 9.0 0.2 3.5 3 1 0 3 3 3 0 AAA domain AAA_27 PF13514.6 OAJ23239.1 - 0.024 14.2 0.1 11 5.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 OAJ23239.1 - 0.029 14.0 0.0 1.7 8.2 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 OAJ23239.1 - 0.03 14.4 11.7 1 9.4 0.3 4.2 4 2 1 5 5 4 0 Dynamin family NTPase_1 PF03266.15 OAJ23239.1 - 0.039 13.9 4.2 12 5.7 0.2 3.6 4 0 0 4 4 3 0 NTPase cobW PF02492.19 OAJ23239.1 - 0.043 13.4 1.3 5.1 6.7 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OAJ23239.1 - 0.049 13.6 0.9 11 6.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 OAJ23239.1 - 0.059 13.6 0.0 4.5 7.6 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 OAJ23239.1 - 0.063 13.0 0.2 9.1 6.0 0.0 3.2 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 OAJ23239.1 - 0.11 11.9 0.6 6.9 6.1 0.1 3.0 4 0 0 4 4 3 0 P-loop containing dynein motor region DUF87 PF01935.17 OAJ23239.1 - 0.18 11.9 5.5 4.8 7.2 0.1 3.7 4 1 1 5 5 4 0 Helicase HerA, central domain Pox_A32 PF04665.12 OAJ23239.1 - 0.22 10.9 3.2 2.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein TsaE PF02367.17 OAJ23239.1 - 0.31 11.1 2.6 4.5 7.3 0.0 3.5 3 1 1 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 OAJ23239.1 - 0.54 9.5 4.5 15 4.8 0.0 3.3 4 0 0 4 4 3 0 Septin CAP PF00188.26 OAJ23240.1 - 2.5e-18 67.1 0.7 4.5e-18 66.3 0.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Tyrosinase PF00264.20 OAJ23240.1 - 0.016 15.5 1.0 0.024 15.0 1.0 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF5349 PF17298.2 OAJ23240.1 - 4.9 6.8 10.0 7.1 6.3 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Formyl_trans_N PF00551.19 OAJ23241.1 - 4.4e-26 91.7 0.1 1.3e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase DnaJ PF00226.31 OAJ23241.1 - 2e-18 66.3 0.1 3.7e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DHH PF01368.20 OAJ23241.1 - 2.1e-07 31.1 0.0 6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 DHH family MAGE PF01454.19 OAJ23243.1 - 9.8e-25 87.5 0.0 6.1e-23 81.7 0.0 3.1 1 1 0 1 1 1 1 MAGE family MRP-L27 PF09809.9 OAJ23244.1 - 1.6e-06 28.0 0.4 2.8e-05 23.9 0.4 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 MFS_1 PF07690.16 OAJ23246.1 - 1.1e-08 34.4 21.1 1.1e-08 34.4 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1761 PF08570.10 OAJ23246.1 - 0.52 10.6 12.7 0.11 12.7 0.7 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) Baculo_PEP_C PF04513.12 OAJ23247.1 - 0.14 12.2 7.1 1.3 9.0 1.5 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG9 PF04109.16 OAJ23248.1 - 1.2e-194 647.8 1.1 1.4e-194 647.6 1.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Cwf_Cwc_15 PF04889.12 OAJ23248.1 - 1 9.0 4.2 1.7 8.3 4.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_hydro_92 PF07971.12 OAJ23249.1 - 2.8e-99 333.1 0.0 4.2e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ23249.1 - 2.1e-43 149.0 0.7 3.1e-43 148.4 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_17 PF00332.18 OAJ23250.1 - 1.6e-08 34.5 0.3 0.00014 21.6 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DDE_3 PF13358.6 OAJ23253.1 - 1.8e-14 53.7 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OAJ23253.1 - 7.6e-10 38.9 2.8 7.6e-10 38.9 2.8 2.9 3 0 0 3 3 3 1 Transposase HTH_Tnp_ISL3 PF13542.6 OAJ23253.1 - 7.6e-06 25.3 2.1 0.00017 20.9 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 OAJ23253.1 - 9.7e-06 25.2 1.7 4.9e-05 23.0 0.1 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 OAJ23253.1 - 3.1e-05 23.7 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 OAJ23253.1 - 9.8e-05 22.5 0.5 0.042 14.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.13 OAJ23253.1 - 0.00031 20.3 0.0 0.00072 19.1 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain GerE PF00196.19 OAJ23253.1 - 0.0013 18.2 0.1 0.0051 16.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_50 PF18024.1 OAJ23253.1 - 0.0029 17.2 0.1 0.0079 15.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 OAJ23253.1 - 0.0082 16.2 0.1 0.023 14.8 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 OAJ23253.1 - 0.022 15.1 0.6 0.044 14.1 0.2 1.8 2 0 0 2 2 1 0 Transposase HTH_29 PF13551.6 OAJ23253.1 - 0.025 14.6 0.1 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 OAJ23253.1 - 0.039 13.6 0.3 0.21 11.3 0.1 2.4 2 0 0 2 2 1 0 Sigma-70, region 4 HTH_32 PF13565.6 OAJ23253.1 - 0.041 14.5 4.1 0.11 13.1 0.4 3.1 2 1 1 3 3 3 0 Homeodomain-like domain YdaS_antitoxin PF15943.5 OAJ23253.1 - 0.084 12.7 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_7 PF02796.15 OAJ23253.1 - 0.11 12.6 0.5 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 OAJ23253.1 - 0.11 12.6 0.3 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix Wbp11 PF09429.10 OAJ23253.1 - 0.12 12.7 5.8 0.14 12.6 4.3 2.0 2 0 0 2 2 1 0 WW domain binding protein 11 HTH_31 PF13560.6 OAJ23253.1 - 0.15 12.4 0.9 0.76 10.2 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Epimerase PF01370.21 OAJ23255.1 - 6.8e-05 22.4 0.0 8.6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ23255.1 - 0.00093 19.1 0.0 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAJ23255.1 - 0.027 13.5 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ23255.1 - 0.036 13.2 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 OAJ23255.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAJ23255.1 - 0.24 10.8 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Med15 PF09606.10 OAJ23256.1 - 0.68 8.5 147.7 0.018 13.8 73.6 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1542 PF07564.11 OAJ23257.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) NosL PF05573.12 OAJ23257.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 NosL Nop14 PF04147.12 OAJ23258.1 - 8e-270 897.9 4.5 1.2e-269 897.2 4.5 1.2 1 0 0 1 1 1 1 Nop14-like family Dus PF01207.17 OAJ23259.1 - 3e-48 164.5 0.0 9.2e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 OAJ23259.1 - 1.7e-07 31.0 5.5 0.0024 17.7 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ23259.1 - 6.9e-07 29.1 13.5 0.0015 18.5 4.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ23259.1 - 2.4e-06 27.2 11.6 0.00012 21.8 2.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OAJ23259.1 - 5.3e-06 27.1 1.0 0.00079 20.1 0.4 2.6 2 0 0 2 2 2 1 Torus domain Lustrin_cystein PF14625.6 OAJ23259.1 - 0.078 13.4 1.7 6.9 7.1 0.3 2.6 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain PPR_2 PF13041.6 OAJ23260.1 - 2.5e-08 34.0 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 OAJ23260.1 - 0.017 15.2 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DUF5560 PF17715.1 OAJ23260.1 - 0.025 14.1 2.1 0.28 10.6 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5560) DUF778 PF05608.12 OAJ23260.1 - 0.57 10.5 2.6 0.62 10.4 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF778) Glyco_hydro_cc PF11790.8 OAJ23261.1 - 2.1e-51 174.8 2.1 2.8e-51 174.4 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Apolipoprotein PF01442.18 OAJ23262.1 - 0.0011 18.9 10.2 0.0022 17.9 10.2 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAJ23262.1 - 0.011 15.8 3.8 0.68 10.0 0.4 2.6 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 OAJ23262.1 - 0.017 15.0 2.8 0.02 14.8 1.1 1.9 2 0 0 2 2 2 0 Prefoldin subunit GAS PF13851.6 OAJ23262.1 - 0.02 14.3 7.0 0.054 12.8 7.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Muted PF14942.6 OAJ23262.1 - 0.023 15.1 2.2 0.023 15.1 2.2 1.5 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein GIDA_assoc PF13932.6 OAJ23262.1 - 0.023 14.9 1.6 0.038 14.2 1.6 1.3 1 0 0 1 1 1 0 GidA associated domain Exonuc_VII_L PF02601.15 OAJ23262.1 - 0.029 13.9 5.2 0.045 13.3 5.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Occludin_ELL PF07303.13 OAJ23262.1 - 0.032 15.0 1.8 0.064 14.0 1.3 1.8 1 1 1 2 2 2 0 Occludin homology domain Cep57_MT_bd PF06657.13 OAJ23262.1 - 0.038 14.4 5.5 0.082 13.4 4.6 2.1 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 OAJ23262.1 - 0.042 14.2 9.5 0.094 13.0 9.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CHAD PF05235.14 OAJ23262.1 - 0.046 13.7 8.2 0.069 13.1 7.9 1.4 1 1 0 1 1 1 0 CHAD domain Cob_adeno_trans PF01923.18 OAJ23262.1 - 0.048 13.8 4.3 1.6 8.8 1.0 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prominin PF05478.11 OAJ23262.1 - 0.053 11.5 0.7 0.075 11.0 0.7 1.3 1 0 0 1 1 1 0 Prominin ApoLp-III PF07464.11 OAJ23262.1 - 0.07 13.2 4.6 0.1 12.7 1.9 2.4 2 1 1 3 3 2 0 Apolipophorin-III precursor (apoLp-III) DUF842 PF05811.13 OAJ23262.1 - 0.088 12.5 8.5 0.052 13.3 5.7 2.0 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CENP-F_leu_zip PF10473.9 OAJ23262.1 - 0.12 12.4 5.7 0.31 11.1 5.7 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 OAJ23262.1 - 0.13 12.6 9.5 0.59 10.5 6.0 3.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 OAJ23262.1 - 0.14 12.4 6.6 1.1 9.6 0.0 2.4 1 1 2 3 3 3 0 Tup N-terminal DUF1640 PF07798.11 OAJ23262.1 - 0.15 12.1 7.4 0.3 11.1 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) IZUMO PF15005.6 OAJ23262.1 - 0.15 12.5 1.9 0.39 11.2 0.7 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF1664 PF07889.12 OAJ23262.1 - 0.32 11.0 5.8 0.93 9.5 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RYDR_ITPR PF01365.21 OAJ23262.1 - 0.33 10.3 5.2 0.54 9.6 5.2 1.3 1 0 0 1 1 1 0 RIH domain KxDL PF10241.9 OAJ23262.1 - 0.64 10.3 8.8 2.9 8.3 5.8 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein HIP1_clath_bdg PF16515.5 OAJ23262.1 - 0.87 10.2 12.9 0.91 10.2 9.4 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spectrin PF00435.21 OAJ23262.1 - 0.89 10.1 7.7 11 6.6 7.7 2.2 1 1 0 1 1 1 0 Spectrin repeat DUF4456 PF14644.6 OAJ23262.1 - 0.94 9.1 11.3 8.2 6.0 10.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) Phage_GPO PF05929.11 OAJ23262.1 - 1.2 8.7 6.3 1.5 8.4 5.8 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fzo_mitofusin PF04799.13 OAJ23262.1 - 2.2 7.8 9.3 14 5.2 1.9 2.5 1 1 1 2 2 2 0 fzo-like conserved region DUF883 PF05957.13 OAJ23262.1 - 3.4 8.3 9.2 32 5.2 3.9 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Cellulase PF00150.18 OAJ23263.1 - 0.037 13.4 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PMT PF02366.18 OAJ23264.1 - 3.4e-16 59.6 1.5 4.3e-16 59.2 1.5 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CxC4 PF18717.1 OAJ23265.1 - 0.00079 19.3 0.5 0.002 17.9 0.5 1.7 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases DUF3330 PF11809.8 OAJ23265.1 - 0.038 14.0 0.1 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) DUF4482 PF14818.6 OAJ23266.1 - 0.21 12.5 4.3 0.096 13.6 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) EXS PF03124.14 OAJ23267.1 - 2.4e-70 237.5 34.4 4.8e-40 137.9 13.4 2.2 1 1 1 2 2 2 2 EXS family SPX PF03105.19 OAJ23267.1 - 2.5e-30 106.7 8.0 2.5e-30 106.7 8.0 1.8 2 0 0 2 2 2 1 SPX domain MMR_HSR1 PF01926.23 OAJ23268.1 - 1e-15 57.8 0.1 1.3e-13 51.1 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ23268.1 - 2.3e-07 30.5 0.1 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ23268.1 - 0.00013 21.9 0.4 0.1 12.5 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ23268.1 - 0.00024 20.7 0.0 0.011 15.3 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAJ23268.1 - 0.00035 20.7 1.3 0.21 11.6 0.1 3.3 2 1 1 3 3 3 1 Dynamin family Herpes_UL56 PF04534.12 OAJ23268.1 - 0.056 12.9 0.1 0.056 12.9 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus UL56 protein InPase PF18823.1 OAJ23270.1 - 0.099 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Inorganic Pyrophosphatase ACPS PF01648.20 OAJ23271.1 - 1.3e-08 35.0 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Dehydrin PF00257.19 OAJ23271.1 - 0.023 15.2 3.6 0.034 14.7 3.6 1.3 1 0 0 1 1 1 0 Dehydrin IMUP PF15761.5 OAJ23271.1 - 0.74 10.5 10.2 1.2 9.9 10.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Helicase_C_2 PF13307.6 OAJ23272.1 - 8.7e-25 87.9 0.0 2.8e-22 79.7 0.0 2.1 1 1 1 2 2 2 2 Helicase C-terminal domain Hist_deacetyl PF00850.19 OAJ23279.1 - 5e-28 98.5 0.0 6.8e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NDC10_II PF16787.5 OAJ23280.1 - 2.2e-18 66.4 0.0 2.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Phage_int_SAM_1 PF02899.17 OAJ23280.1 - 0.078 13.3 0.1 9.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain NDC10_II PF16787.5 OAJ23281.1 - 2e-63 214.4 0.0 2.8e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ23281.1 - 5.3e-17 61.9 1.8 1e-16 61.0 1.8 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes CCDC24 PF15669.5 OAJ23281.1 - 0.00037 20.4 0.8 0.00081 19.3 0.8 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family TFIIA PF03153.13 OAJ23282.1 - 0.00056 20.0 5.0 0.00056 20.0 5.0 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 OAJ23282.1 - 0.029 14.8 5.3 0.17 12.4 5.3 2.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type BUD22 PF09073.10 OAJ23282.1 - 1.1 8.6 16.5 1.9 7.8 16.5 1.3 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.12 OAJ23282.1 - 8.4 5.2 11.8 13 4.5 11.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Methyltransf_23 PF13489.6 OAJ23283.1 - 5.9e-05 23.0 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ23283.1 - 0.052 14.3 0.0 0.35 11.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain NOA36 PF06524.12 OAJ23283.1 - 0.37 10.1 12.0 0.8 9.0 12.0 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ23283.1 - 5.9 5.1 15.6 0.056 11.7 7.7 1.5 2 0 0 2 2 2 0 CDC45-like protein RGS PF00615.19 OAJ23284.1 - 1.1e-11 45.1 0.0 1.1e-07 32.2 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain His_Phos_1 PF00300.22 OAJ23285.1 - 5e-18 65.5 0.0 7.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SVIP PF15811.5 OAJ23285.1 - 0.11 12.9 4.4 0.28 11.7 4.4 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Sdh_cyt PF01127.22 OAJ23286.1 - 2.9e-23 82.2 4.9 3.9e-23 81.8 4.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pam16 PF03656.13 OAJ23286.1 - 0.099 12.7 0.3 0.14 12.2 0.3 1.2 1 0 0 1 1 1 0 Pam16 AAA_18 PF13238.6 OAJ23287.1 - 2.3e-25 89.7 0.0 1.1e-24 87.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ23287.1 - 0.0099 16.3 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAJ23287.1 - 0.012 15.7 0.8 1.6 8.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAJ23287.1 - 0.017 15.6 0.0 0.84 10.1 0.0 2.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAJ23287.1 - 0.031 14.5 2.1 0.044 14.0 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ23287.1 - 0.032 14.5 0.0 0.074 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 OAJ23287.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 OAJ23287.1 - 0.038 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 OAJ23287.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 OAJ23287.1 - 0.083 12.2 0.3 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ADK PF00406.22 OAJ23287.1 - 0.11 12.6 0.1 9.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_24 PF13479.6 OAJ23287.1 - 0.14 11.8 0.0 0.4 10.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain DUF383 PF04063.14 OAJ23288.1 - 1.1e-49 168.7 0.0 8.5e-49 165.8 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAJ23288.1 - 9e-18 63.9 2.8 1.9e-17 62.9 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF883 PF05957.13 OAJ23288.1 - 0.087 13.4 0.5 0.087 13.4 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4805 PF16063.5 OAJ23288.1 - 0.19 11.0 2.5 0.32 10.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Cpn60_TCP1 PF00118.24 OAJ23289.1 - 7.4e-147 489.9 13.7 1.6e-92 310.7 4.7 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3808 PF10300.9 OAJ23290.1 - 8e-77 259.0 0.0 1.3e-76 258.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.20 OAJ23290.1 - 5.6e-31 107.4 0.0 1.1e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ23290.1 - 9.8e-13 48.1 0.6 2.9e-12 46.6 0.6 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ23290.1 - 4.4e-10 39.8 0.0 1.2e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TPR_8 PF13181.6 OAJ23290.1 - 0.13 12.5 2.1 0.48 10.8 0.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23290.1 - 0.2 11.8 10.9 24 5.3 1.7 5.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ23290.1 - 0.88 9.5 7.3 1.2 9.1 1.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Adeno_PV PF03910.13 OAJ23290.1 - 3.7 6.2 5.0 6.4 5.4 5.0 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV TPR_7 PF13176.6 OAJ23290.1 - 3.9 7.7 6.9 8.5 6.7 0.7 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ23290.1 - 4.1 7.8 6.1 4.3 7.7 2.3 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 OAJ23291.1 - 1.8e-13 50.6 0.1 5.1e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OAJ23291.1 - 4.2e-06 26.8 2.3 2.9e-05 24.1 2.3 2.3 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OAJ23291.1 - 6.7e-05 22.7 0.0 0.0032 17.3 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-C2H2 PF00096.26 OAJ23296.1 - 6.7e-07 29.4 2.2 0.0024 18.3 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ23296.1 - 2e-06 28.2 3.0 0.0049 17.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAJ23296.1 - 0.0002 21.6 2.2 0.11 12.9 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OAJ23296.1 - 0.00071 19.8 5.1 0.014 15.6 0.7 2.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding HypA PF01155.19 OAJ23296.1 - 0.026 14.5 0.2 0.041 13.9 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ima1_N PF09779.9 OAJ23296.1 - 0.029 15.2 0.0 0.037 14.9 0.0 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-C2H2_9 PF16293.5 OAJ23296.1 - 0.13 12.1 0.2 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) PyrI_C PF02748.15 OAJ23296.1 - 2.2 8.3 3.8 4.5 7.3 0.3 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ank_2 PF12796.7 OAJ23297.1 - 9e-31 106.3 0.1 2.2e-09 37.8 0.1 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ23297.1 - 7.8e-26 90.1 3.9 7.2e-10 39.2 0.0 5.4 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ23297.1 - 4.4e-25 87.4 11.3 1.1e-07 32.0 0.1 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) SPX PF03105.19 OAJ23297.1 - 3.7e-24 86.4 3.8 1.8e-15 57.8 0.4 4.3 3 2 0 3 3 3 2 SPX domain Ank_3 PF13606.6 OAJ23297.1 - 3.7e-21 73.0 4.0 0.00085 19.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 OAJ23297.1 - 8.8e-20 70.2 5.9 1.8e-05 24.9 0.0 6.9 6 1 0 6 6 6 3 Ankyrin repeat GDPD PF03009.17 OAJ23297.1 - 8.1e-13 48.7 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RVT_2 PF07727.14 OAJ23299.1 - 1.6e-59 201.5 0.0 2.3e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ23299.1 - 4.6e-17 62.3 0.3 1.9e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ23299.1 - 1.4e-08 34.5 0.4 1.7e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAJ23299.1 - 5.2e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ23299.1 - 4.4e-05 23.4 7.6 0.013 15.6 0.9 2.5 2 0 0 2 2 2 2 Zinc knuckle rve_3 PF13683.6 OAJ23299.1 - 0.0014 18.4 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RNA_bind PF08675.11 OAJ23299.1 - 0.068 13.2 0.1 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain DUF1820 PF08850.11 OAJ23299.1 - 0.074 13.6 0.1 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1820) zf-CCHC_3 PF13917.6 OAJ23299.1 - 0.75 9.8 2.6 11 6.1 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle Med3 PF11593.8 OAJ23300.1 - 1.5 7.9 10.9 1.6 7.9 10.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Integrase_H2C2 PF17921.1 OAJ23301.1 - 6.7e-15 54.9 0.0 1.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ23301.1 - 2.1e-13 50.1 0.1 5e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ23301.1 - 5.1e-11 42.8 0.0 1.8e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ23301.1 - 9.2e-11 41.7 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ23301.1 - 0.00019 22.0 0.6 0.00052 20.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ23301.1 - 0.012 16.2 0.0 0.042 14.4 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ23301.1 - 0.043 14.1 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 OAJ23301.1 - 0.048 14.0 0.1 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DDE_Tnp_4 PF13359.6 OAJ23302.1 - 3.6e-32 111.2 0.0 4.8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ23302.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ23302.1 - 3.6e-06 26.7 0.0 4.3e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 OAJ23302.1 - 0.00032 20.3 0.1 0.001 18.8 0.1 1.9 1 1 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Ribosomal_60s PF00428.19 OAJ23303.1 - 8.5e-27 93.6 6.7 1e-26 93.3 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein THOC2_N PF16134.5 OAJ23303.1 - 0.069 11.8 0.1 0.08 11.6 0.1 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Ntox27 PF15531.6 OAJ23303.1 - 0.07 13.0 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial toxin 27 CRM1_C PF08767.11 OAJ23304.1 - 2.9e-122 407.8 4.2 3.3e-122 407.7 1.1 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OAJ23304.1 - 2.1e-39 135.0 2.0 2.1e-39 135.0 2.0 3.8 4 1 1 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAJ23304.1 - 1.6e-33 114.1 4.1 5.4e-33 112.5 4.1 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAJ23304.1 - 8.2e-29 99.5 0.8 8.2e-29 99.5 0.8 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAJ23304.1 - 8.7e-20 69.9 2.5 2.6e-19 68.4 2.5 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAJ23304.1 - 6.1e-15 54.9 0.5 2.8e-14 52.8 0.5 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2294 PF10057.9 OAJ23304.1 - 0.0071 16.5 1.2 5.8 7.1 0.2 3.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2294) DUF1654 PF07867.11 OAJ23304.1 - 0.65 9.8 2.4 12 5.7 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DnaJ PF00226.31 OAJ23305.1 - 3.6e-06 27.0 0.2 5.3e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain HsbA PF12296.8 OAJ23306.1 - 1.6e-17 64.0 7.3 2.8e-17 63.3 7.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A TPP_enzyme_C PF02775.21 OAJ23306.1 - 0.078 12.8 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.25 OAJ23307.1 - 2.6e-71 240.1 0.0 3.1e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23307.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ23307.1 - 0.0041 16.5 0.0 0.095 12.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OAJ23307.1 - 0.062 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OAJ23307.1 - 0.066 13.1 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ23307.1 - 0.42 9.5 2.3 2.8 6.8 0.0 2.5 3 0 0 3 3 3 0 Haspin like kinase domain MINDY_DUB PF04424.13 OAJ23312.1 - 1.6e-22 79.7 0.0 1.5e-21 76.6 0.0 2.3 2 1 0 2 2 2 1 MINDY deubiquitinase InaF-motif PF15018.6 OAJ23313.1 - 0.27 11.2 1.3 0.3 11.0 0.2 1.5 2 0 0 2 2 2 0 TRP-interacting helix TFIIA PF03153.13 OAJ23313.1 - 0.54 10.2 4.0 0.7 9.8 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP_N PF14636.6 OAJ23313.1 - 0.8 10.7 4.3 1.2 10.1 4.3 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Hydrolase PF00702.26 OAJ23317.1 - 6.7e-05 23.3 0.2 0.00011 22.6 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ23317.1 - 0.0018 18.1 0.2 0.0027 17.5 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Transposase_21 PF02992.14 OAJ23318.1 - 8.6e-08 31.7 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Period_C PF12114.8 OAJ23321.1 - 6.7 6.2 8.7 8.7 5.9 8.7 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DIM1 PF02966.16 OAJ23322.1 - 8.9e-66 219.7 0.1 1e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAJ23322.1 - 0.00069 19.6 0.0 0.00087 19.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ23322.1 - 0.027 14.8 0.1 0.042 14.2 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like DUF3192 PF11399.8 OAJ23322.1 - 0.11 12.5 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Myb_Cef PF11831.8 OAJ23324.1 - 2.8e-56 190.7 0.3 2.8e-56 190.7 0.3 4.3 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAJ23324.1 - 3e-23 81.7 4.5 4.2e-11 42.8 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ23324.1 - 8.7e-20 70.7 6.9 4.6e-13 49.2 3.5 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2271 PF10029.9 OAJ23324.1 - 0.0086 15.7 0.3 0.02 14.5 0.3 1.6 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) VAPB_antitox PF02697.14 OAJ23324.1 - 0.013 16.3 1.8 0.095 13.5 1.8 2.6 1 0 0 1 1 1 0 Putative antitoxin Rap1_C PF11626.8 OAJ23324.1 - 0.2 11.8 1.2 2.2 8.4 0.1 2.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Peptidase_C2 PF00648.21 OAJ23325.1 - 3.8e-23 81.9 0.0 7.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAJ23325.1 - 1.8e-17 63.9 0.0 1.4e-08 35.1 0.0 3.1 3 0 0 3 3 3 2 Calpain large subunit, domain III E1-E2_ATPase PF00122.20 OAJ23328.1 - 0.11 12.0 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Sec1 PF00995.23 OAJ23329.1 - 5.4e-21 75.4 0.1 2.7e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Sec1 family LSM PF01423.22 OAJ23329.1 - 0.076 12.7 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 LSM domain Acetyltransf_1 PF00583.25 OAJ23334.1 - 1.3e-07 31.8 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ23334.1 - 2.8e-06 27.6 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ23334.1 - 0.00011 22.1 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 OAJ23334.1 - 0.00014 21.8 0.1 0.068 13.1 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAJ23334.1 - 0.007 15.9 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 OAJ23334.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAT PF02259.23 OAJ23335.1 - 5.4e-65 219.9 2.0 5.4e-65 219.9 2.0 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAJ23335.1 - 4.3e-28 98.8 0.0 2.6e-27 96.2 0.0 2.4 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAJ23335.1 - 0.032 14.1 0.2 0.078 12.8 0.2 1.7 1 0 0 1 1 1 0 FATC domain Ribosomal_L13e PF01294.18 OAJ23336.1 - 1.7e-69 233.3 6.9 2.4e-69 232.8 6.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.19 OAJ23338.1 - 3.3 8.3 10.0 0.56 10.8 5.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein U3_assoc_6 PF08640.11 OAJ23340.1 - 4.2e-13 49.2 0.2 1.4e-11 44.3 0.1 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Apc13p PF05839.11 OAJ23340.1 - 4.6 7.5 8.2 5.7 7.2 0.0 3.3 3 0 0 3 3 3 0 Apc13p protein MoaC PF01967.21 OAJ23342.1 - 4.9e-44 149.7 3.0 2.1e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.13 OAJ23343.1 - 4.8e-33 113.8 0.0 3.7e-32 111.0 0.0 2.2 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAJ23343.1 - 7.8e-29 101.2 0.0 1.2e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAJ23343.1 - 8.8e-06 26.0 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAJ23343.1 - 0.19 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain ELFV_dehydrog PF00208.21 OAJ23347.1 - 3.8e-49 167.6 0.2 4.7e-49 167.3 0.2 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2255 PF10012.9 OAJ23347.1 - 0.023 14.8 0.2 0.053 13.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) SKN1 PF03935.15 OAJ23348.1 - 7.3e-99 331.4 0.0 2.8e-60 204.2 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lipase_3 PF01764.25 OAJ23349.1 - 5.2e-14 52.3 0.0 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ23349.1 - 0.019 15.5 0.0 0.019 15.5 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ23349.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 OAJ23349.1 - 0.069 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TMEM171 PF15471.6 OAJ23349.1 - 0.084 11.8 4.5 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF3246 PF11596.8 OAJ23349.1 - 0.099 12.1 0.7 0.24 10.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2974 PF11187.8 OAJ23349.1 - 0.2 11.2 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SKN1 PF03935.15 OAJ23352.1 - 7.1e-20 70.9 0.0 7.6e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ23353.1 - 3.6e-13 48.8 0.0 4.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aconitase PF00330.20 OAJ23354.1 - 1.6e-150 502.1 0.0 2.6e-150 501.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ23354.1 - 3.1e-43 147.2 0.0 5.5e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NUDIX PF00293.28 OAJ23355.1 - 7.7e-13 48.6 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAJ23355.1 - 4.6e-10 40.1 3.2 1.8e-09 38.2 3.2 2.1 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain SKN1 PF03935.15 OAJ23356.1 - 6.3e-133 443.8 1.4 9.4e-94 314.6 1.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ23357.1 - 7.3e-139 463.4 14.0 9.5e-138 459.7 14.0 2.1 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ23358.1 - 4.6e-176 586.1 5.2 7.7e-94 314.9 1.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Clathrin_propel PF01394.20 OAJ23358.1 - 0.0043 17.3 0.3 3.9 7.9 0.0 2.7 2 0 0 2 2 2 2 Clathrin propeller repeat MBG PF17883.1 OAJ23358.1 - 0.016 15.8 0.5 3 8.5 0.1 2.7 2 0 0 2 2 2 0 MBG domain WGG PF10273.9 OAJ23359.1 - 1.4e-21 76.9 0.0 2.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 PPP4R2 PF09184.11 OAJ23359.1 - 0.0064 16.1 6.7 0.0086 15.7 6.7 1.2 1 0 0 1 1 1 1 PPP4R2 RRP7 PF12923.7 OAJ23359.1 - 0.0096 16.1 0.6 0.021 14.9 0.6 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CDC45 PF02724.14 OAJ23359.1 - 0.055 11.8 9.9 0.068 11.5 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 OAJ23359.1 - 0.73 8.9 15.7 1.2 8.2 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 OAJ23359.1 - 0.99 9.7 11.8 0.053 13.8 6.1 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 OAJ23359.1 - 3.3 5.8 11.6 3.4 5.7 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 OAJ23359.1 - 7.5 6.6 8.6 13 5.8 8.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Oxysterol_BP PF01237.18 OAJ23365.1 - 7e-68 229.1 0.5 1.7e-57 195.0 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein FSH1 PF03959.13 OAJ23366.1 - 5.3e-54 183.1 0.0 6.1e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OAJ23366.1 - 0.028 14.0 0.2 0.059 12.9 0.2 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAJ23366.1 - 0.087 12.6 0.1 0.76 9.5 0.1 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OAJ23366.1 - 0.15 12.0 0.0 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAJ23366.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IGPD PF00475.18 OAJ23367.1 - 3.6e-60 202.5 0.8 4.9e-60 202.0 0.3 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF913 PF06025.12 OAJ23369.1 - 1.3e-91 307.3 0.0 1.3e-91 307.3 0.0 7.2 8 1 0 8 8 8 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 OAJ23369.1 - 2.3e-88 297.0 1.7 2.3e-88 297.0 1.7 4.8 6 1 0 6 6 6 1 Domain of Unknown Function (DUF908) UBM PF14377.6 OAJ23369.1 - 1.1e-19 69.2 12.0 2.4e-11 42.7 0.6 4.0 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 OAJ23369.1 - 1.7e-09 37.4 0.1 4.9e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain COX15-CtaA PF02628.15 OAJ23370.1 - 3e-88 296.0 13.5 2.9e-86 289.5 13.5 3.3 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein GYF PF02213.16 OAJ23371.1 - 0.0074 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 GYF domain ParA PF10609.9 OAJ23372.1 - 4.6e-80 268.6 0.1 3.3e-42 144.7 0.0 3.0 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ23372.1 - 8.4e-06 25.9 0.5 0.00068 19.7 0.3 2.8 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OAJ23372.1 - 0.00073 18.8 0.2 0.0014 17.8 0.2 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase SelB-wing_3 PF09107.11 OAJ23372.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix RsgA_GTPase PF03193.16 OAJ23372.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_31 PF13614.6 OAJ23372.1 - 0.027 14.4 0.3 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 OAJ23372.1 - 0.055 12.9 0.0 6.1 6.2 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 OAJ23372.1 - 0.058 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ23372.1 - 0.062 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OAJ23372.1 - 0.072 13.5 0.0 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 OAJ23372.1 - 0.093 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_26 PF13500.6 OAJ23372.1 - 0.12 12.2 0.0 0.91 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4611 PF15387.6 OAJ23372.1 - 1.7 8.9 5.5 3.6 7.9 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ABC_tran PF00005.27 OAJ23373.1 - 2.5e-42 144.6 0.0 7.9e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ23373.1 - 4.1e-41 141.4 29.3 1.8e-23 83.6 5.6 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ23373.1 - 2.1e-09 37.2 0.0 6.1e-05 22.6 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ23373.1 - 1.3e-05 25.5 0.3 0.024 14.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAJ23373.1 - 0.00044 19.9 0.0 0.56 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 OAJ23373.1 - 0.00085 18.5 0.1 0.3 10.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 OAJ23373.1 - 0.0014 18.3 1.4 0.15 11.9 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain ATPase PF06745.13 OAJ23373.1 - 0.02 14.3 0.2 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.9 OAJ23373.1 - 0.063 12.2 0.1 8.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 OAJ23373.1 - 0.073 12.6 0.7 0.42 10.2 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 OAJ23373.1 - 0.075 12.8 0.4 18 5.1 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 OAJ23373.1 - 0.077 12.7 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OAJ23373.1 - 0.14 11.6 0.2 4 6.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 OAJ23373.1 - 0.14 11.6 0.0 7.2 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAJ23373.1 - 0.16 11.7 1.7 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_16 PF13191.6 OAJ23373.1 - 0.48 10.8 10.3 0.82 10.0 3.3 3.6 3 1 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 OAJ23373.1 - 0.78 10.2 9.4 1.9 8.9 0.1 3.3 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 OAJ23373.1 - 1.1 9.3 3.9 0.25 11.4 0.1 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain Roughex PF06020.11 OAJ23374.1 - 0.15 11.1 1.2 0.24 10.5 1.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Sigma70_ner PF04546.13 OAJ23374.1 - 5.2 6.9 8.6 12 5.7 8.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NCBP3 PF10309.9 OAJ23375.1 - 2.7e-11 43.1 0.0 4.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DASH_Spc19 PF08287.11 OAJ23376.1 - 3.8e-13 49.6 15.3 8.1e-13 48.6 6.8 3.4 3 1 0 3 3 3 1 Spc19 Filament PF00038.21 OAJ23376.1 - 0.0018 17.9 2.9 0.0029 17.2 2.9 1.3 1 0 0 1 1 1 1 Intermediate filament protein DUF812 PF05667.11 OAJ23376.1 - 0.012 14.6 9.1 0.014 14.3 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GCN5L1 PF06320.13 OAJ23376.1 - 0.023 14.8 0.1 0.023 14.8 0.1 2.7 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) BLOC1_2 PF10046.9 OAJ23376.1 - 0.52 10.6 7.9 4 7.8 1.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHR10 PF18595.1 OAJ23376.1 - 0.53 10.3 16.5 0.4 10.7 8.4 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FluMu_N PF17891.1 OAJ23376.1 - 0.55 10.0 0.1 0.55 10.0 0.1 2.3 3 0 0 3 3 3 0 Mu-like prophage FluMu N-terminal domain DUF4140 PF13600.6 OAJ23376.1 - 2.3 8.7 12.4 0.54 10.7 0.2 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TubC_N PF18563.1 OAJ23377.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TubC N-terminal docking domain MIP PF00230.20 OAJ23378.1 - 2.4e-45 155.0 5.9 3.5e-45 154.5 5.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein Apt1 PF10351.9 OAJ23383.1 - 2.6e-117 392.6 1.0 2.6e-117 392.6 1.0 3.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 OAJ23383.1 - 4.6e-60 203.9 0.0 3.6e-59 200.9 0.0 2.2 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 OAJ23383.1 - 1.2e-44 152.2 0.0 2.3e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OAJ23383.1 - 4.9e-38 130.5 0.0 1e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 OAJ23383.1 - 3.4e-23 82.3 0.1 3.4e-22 79.1 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain ARID PF01388.21 OAJ23384.1 - 1.5e-16 60.8 0.0 1.5e-16 60.8 0.0 4.3 4 1 0 4 4 4 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 OAJ23385.1 - 7.7e-72 241.8 0.0 1e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23385.1 - 3.9e-30 105.0 0.0 2.5e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ23385.1 - 3.1e-07 30.0 2.2 0.00087 18.7 0.1 3.0 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAJ23385.1 - 0.022 13.6 0.0 0.073 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OAJ23385.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_2 PF13519.6 OAJ23386.1 - 5.4e-06 27.0 0.0 1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAJ23386.1 - 9.8e-05 22.7 0.0 0.00025 21.4 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Abhydrolase_3 PF07859.13 OAJ23389.1 - 3.9e-23 82.4 0.0 5e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 OAJ23389.1 - 0.0062 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 OAJ23389.1 - 0.0069 16.0 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family WD40 PF00400.32 OAJ23390.1 - 6.1e-11 42.7 17.1 0.046 14.6 0.5 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ23390.1 - 2.8e-08 34.0 0.1 0.0018 18.5 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 OAJ23390.1 - 0.0067 15.2 0.6 0.27 9.9 0.8 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1748 PF08520.10 OAJ23391.1 - 2.7e-27 94.4 0.0 3e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Sad1_UNC PF07738.13 OAJ23392.1 - 5.4e-07 29.7 0.1 0.046 13.7 0.2 2.9 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Moricin PF06451.11 OAJ23392.1 - 0.04 13.7 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Moricin PRKCSH-like PF12999.7 OAJ23393.1 - 7.2e-43 146.4 6.5 7.2e-43 146.4 6.5 2.2 1 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OAJ23393.1 - 1.3e-27 96.3 0.1 3.3e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAJ23393.1 - 1e-09 39.2 1.4 2.4e-09 38.1 1.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Effector_1 PF04518.12 OAJ23393.1 - 0.00077 18.7 0.9 0.0013 17.9 0.9 1.3 1 0 0 1 1 1 1 Effector from type III secretion system DUF2968 PF11180.8 OAJ23393.1 - 0.0012 18.5 7.3 0.028 14.1 7.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.9 OAJ23393.1 - 0.0039 16.1 0.4 0.0061 15.5 0.4 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain bZIP_1 PF00170.21 OAJ23393.1 - 0.1 12.7 7.1 2.6 8.2 1.7 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF3584 PF12128.8 OAJ23393.1 - 0.11 10.0 6.8 0.012 13.2 2.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HALZ PF02183.18 OAJ23393.1 - 0.14 12.4 3.2 0.33 11.2 3.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF773 PF05600.12 OAJ23393.1 - 0.19 10.4 0.0 0.19 10.4 0.0 2.6 2 1 0 3 3 3 0 CDK5 regulatory subunit-associated protein 3 Mt_ATP-synt_B PF05405.14 OAJ23393.1 - 0.2 11.3 1.7 0.42 10.2 1.7 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) GAS PF13851.6 OAJ23393.1 - 0.62 9.4 7.9 0.088 12.2 3.7 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 OAJ23393.1 - 0.89 9.0 6.8 0.3 10.6 3.9 1.7 2 0 0 2 2 2 0 Leucine zipper UPF0242 PF06785.11 OAJ23393.1 - 1 9.4 6.2 14 5.8 6.2 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Gp-FAR-1 PF05823.12 OAJ23393.1 - 2.1 8.7 5.1 0.55 10.6 1.0 2.1 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ABC_tran_CTD PF16326.5 OAJ23393.1 - 4.7 7.5 10.2 55 4.1 6.0 3.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain Glycoprotein_G PF00802.19 OAJ23394.1 - 0.003 17.0 15.1 0.0049 16.3 15.1 1.3 1 0 0 1 1 1 1 Pneumovirus attachment glycoprotein G DUF4894 PF16235.5 OAJ23394.1 - 0.082 13.3 3.1 0.8 10.1 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4894) QueF_N PF14819.6 OAJ23394.1 - 0.16 12.3 1.4 3.9 7.8 0.0 3.0 2 1 1 3 3 3 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Polysacc_deac_1 PF01522.21 OAJ23398.1 - 1.8e-16 60.2 0.0 2.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Ets PF00178.22 OAJ23399.1 - 0.14 12.7 0.0 0.95 10.0 0.0 2.4 2 0 0 2 2 2 0 Ets-domain DUF3808 PF10300.9 OAJ23401.1 - 8.1e-82 275.4 0.0 2.2e-81 274.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 OAJ23401.1 - 2.1e-05 24.3 0.9 0.058 13.5 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ23401.1 - 0.00031 20.7 0.3 0.1 12.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ23401.1 - 0.0029 18.1 0.4 3.2 8.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ23401.1 - 0.077 13.7 0.1 4.5 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 OAJ23401.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family TPR_1 PF00515.28 OAJ23401.1 - 0.16 11.9 0.9 1.5 8.8 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HIT PF01230.23 OAJ23402.1 - 4.4e-22 78.6 0.1 7.1e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ23402.1 - 1.1e-10 42.0 0.0 1.8e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAJ23402.1 - 4e-06 26.7 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Phage_integrase PF00589.22 OAJ23404.1 - 6.5e-05 22.8 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Pkinase PF00069.25 OAJ23405.1 - 6.4e-32 111.0 0.0 9.2e-30 103.9 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain FHA PF00498.26 OAJ23405.1 - 1e-09 38.6 0.1 2e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.17 OAJ23405.1 - 1.2e-09 37.9 0.0 6.8e-07 28.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Yop-YscD_cpl PF16697.5 OAJ23405.1 - 0.00022 21.5 0.0 0.00048 20.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 OAJ23405.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 FHA domain Kinase-like PF14531.6 OAJ23405.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AA_permease PF00324.21 OAJ23406.1 - 1.6e-134 449.1 37.4 1.9e-134 448.9 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ23406.1 - 8.2e-42 143.5 41.6 1.1e-41 143.1 41.6 1.2 1 0 0 1 1 1 1 Amino acid permease RVT_3 PF13456.6 OAJ23407.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like DUF4685 PF15737.5 OAJ23407.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) SPOB_ab PF14682.6 OAJ23407.1 - 0.24 11.5 0.0 0.45 10.6 0.0 1.4 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal LRR_8 PF13855.6 OAJ23408.1 - 6e-09 35.5 17.3 9.1e-09 35.0 8.5 4.4 6 0 0 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 OAJ23408.1 - 8.5e-09 35.6 19.7 4.4e-06 27.0 1.6 5.6 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAJ23408.1 - 6.4e-05 22.5 3.0 0.086 12.3 1.8 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OAJ23408.1 - 0.62 10.3 0.0 0.62 10.3 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat LSM PF01423.22 OAJ23409.1 - 5.1e-16 58.1 0.1 6.1e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OAJ23409.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain PROCN PF08083.11 OAJ23411.1 - 3e-225 747.5 7.4 5.2e-225 746.7 7.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAJ23411.1 - 7.1e-126 418.4 0.5 1.3e-125 417.6 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAJ23411.1 - 5.2e-88 293.0 2.5 1.5e-87 291.5 2.5 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAJ23411.1 - 1.7e-82 274.8 2.9 1.7e-82 274.8 2.9 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAJ23411.1 - 1.5e-65 219.3 0.0 2.8e-65 218.4 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 OAJ23411.1 - 4.9e-45 151.8 0.1 1.2e-44 150.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OAJ23411.1 - 1.7e-39 134.6 0.0 3.3e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 OAJ23411.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FHA PF00498.26 OAJ23412.1 - 9e-05 22.8 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Plk4_PB1 PF18190.1 OAJ23413.1 - 0.084 13.0 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 DUF2370 PF10176.9 OAJ23414.1 - 2e-68 230.4 0.0 7.2e-68 228.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF3611 PF12263.8 OAJ23414.1 - 0.055 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF202 PF02656.15 OAJ23414.1 - 0.4 11.1 4.6 0.26 11.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) ECH_1 PF00378.20 OAJ23416.1 - 4.3e-40 137.6 0.9 2.3e-20 73.0 0.1 3.8 3 1 0 4 4 4 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ23416.1 - 1.2e-21 77.6 0.2 1.1e-10 41.6 0.0 2.8 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase GET2 PF08690.10 OAJ23419.1 - 8.7e-11 42.0 0.0 3.9e-06 26.8 0.0 2.5 2 1 0 2 2 2 2 GET complex subunit GET2 DUF676 PF05057.14 OAJ23420.1 - 0.0038 16.8 0.0 0.0073 15.8 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAJ23420.1 - 0.05 14.2 5.1 0.13 12.9 5.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family CwsA PF10814.8 OAJ23420.1 - 0.12 12.6 1.1 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA SLATT_1 PF18181.1 OAJ23420.1 - 0.16 11.9 0.3 0.42 10.5 0.3 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PGAP1 PF07819.13 OAJ23420.1 - 0.37 10.5 2.3 1.2 8.8 2.3 1.8 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 OAJ23420.1 - 1.5 8.1 4.9 0.52 9.5 0.4 2.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 NDUFA12 PF05071.16 OAJ23422.1 - 1.8e-09 38.3 0.1 3.2e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hid1 PF12722.7 OAJ23422.1 - 1.3 7.0 3.5 1.4 7.0 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UDPG_MGDP_dh_N PF03721.14 OAJ23423.1 - 7e-62 208.3 0.0 1.3e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OAJ23423.1 - 1.2e-34 118.9 0.1 2.3e-33 114.8 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OAJ23423.1 - 1.2e-32 111.9 0.0 2.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 OAJ23423.1 - 0.0086 16.6 0.1 7.1 7.3 0.1 2.9 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OAJ23423.1 - 0.054 13.5 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 OAJ23423.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAJ23423.1 - 0.14 12.3 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UBX PF00789.20 OAJ23425.1 - 7.9e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain NUDIX_4 PF14815.6 OAJ23426.1 - 1.8e-15 56.9 0.0 6.6e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 OAJ23426.1 - 2.9e-14 53.4 0.0 6.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ23426.1 - 0.0001 22.0 0.1 0.00024 20.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Bul1_C PF04426.12 OAJ23426.1 - 0.014 14.8 2.1 0.027 13.9 2.1 1.4 1 0 0 1 1 1 0 Bul1 C terminus PG_binding_2 PF08823.11 OAJ23426.1 - 0.056 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Pannexin_like PF12534.8 OAJ23426.1 - 5.6 6.0 9.0 9.8 5.2 9.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 EAP30 PF04157.16 OAJ23427.1 - 6.4e-55 186.0 0.0 8e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Defensin_2 PF01097.18 OAJ23428.1 - 0.042 13.8 1.4 0.11 12.4 1.4 1.7 1 0 0 1 1 1 0 Arthropod defensin TPT PF03151.16 OAJ23429.1 - 2e-24 86.5 14.0 2.5e-24 86.2 14.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ23429.1 - 1.5e-10 41.4 22.5 3.2e-05 24.1 7.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OAJ23429.1 - 5.9e-05 22.5 14.4 5.9e-05 22.5 14.4 1.6 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 OAJ23429.1 - 0.15 11.3 17.5 0.22 10.7 15.3 2.0 1 1 0 1 1 1 0 UAA transporter family ADH_zinc_N_2 PF13602.6 OAJ23430.1 - 2.6e-10 41.5 0.0 6.9e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ23430.1 - 0.0002 21.2 0.3 0.00041 20.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ23430.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4150 PF13665.6 OAJ23430.1 - 0.02 15.1 0.6 11 6.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4150) RhlB PF12300.8 OAJ23431.1 - 0.022 14.9 4.0 0.022 14.9 4.0 1.8 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Prefoldin_3 PF13758.6 OAJ23431.1 - 0.054 13.6 0.6 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit Serglycin PF04360.12 OAJ23431.1 - 0.064 13.2 3.6 0.12 12.3 3.6 1.4 1 0 0 1 1 1 0 Serglycin AKNA PF12443.8 OAJ23431.1 - 0.1 13.2 0.4 0.27 11.9 0.2 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF4407 PF14362.6 OAJ23431.1 - 2 7.7 8.0 4.1 6.7 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SAP PF02037.27 OAJ23432.1 - 3.5e-10 39.4 0.4 5.8e-10 38.7 0.4 1.4 1 0 0 1 1 1 1 SAP domain Presenilin PF01080.17 OAJ23432.1 - 1.4 7.6 3.1 3 6.5 3.1 1.6 1 0 0 1 1 1 0 Presenilin LPP20 PF02169.16 OAJ23432.1 - 3.8 7.9 18.7 1.5 9.2 2.0 4.0 4 0 0 4 4 4 0 LPP20 lipoprotein HAGH_C PF16123.5 OAJ23433.1 - 6.4e-19 68.2 0.0 1.2e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAJ23433.1 - 5.6e-10 39.6 2.7 2.7e-07 30.8 2.7 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAJ23433.1 - 0.0034 16.9 0.3 0.0087 15.6 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RCC1 PF00415.18 OAJ23434.1 - 2.2e-22 79.4 13.7 4.5e-08 33.6 0.4 8.3 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ23434.1 - 1.2e-12 47.3 17.2 5.9e-08 32.3 1.3 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat SUIM_assoc PF16619.5 OAJ23435.1 - 0.28 11.3 4.6 1.5 8.9 4.6 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mitofilin PF09731.9 OAJ23436.1 - 4e-63 214.3 40.3 1.2e-31 110.3 22.6 3.7 2 1 2 4 4 4 4 Mitochondrial inner membrane protein Thiolase_N PF00108.23 OAJ23437.1 - 8.9e-93 310.4 2.8 1.4e-92 309.8 2.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ23437.1 - 2.4e-43 146.7 1.6 4e-42 142.7 0.5 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ23437.1 - 4.9e-07 29.6 2.4 1.8e-05 24.5 1.2 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ23437.1 - 2.7 7.9 9.6 2.9 7.8 0.2 3.8 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1264 PF06884.11 OAJ23439.1 - 2e-48 164.2 0.0 3.5e-48 163.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1264) SRPRB PF09439.10 OAJ23440.1 - 1.2e-09 37.9 0.1 2.6e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAJ23440.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF374 PF04028.13 OAJ23440.1 - 0.023 14.3 0.7 0.08 12.5 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF374) AAA_16 PF13191.6 OAJ23440.1 - 0.024 15.0 1.9 0.16 12.4 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 OAJ23440.1 - 0.034 14.3 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OAJ23440.1 - 0.04 14.2 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAJ23440.1 - 0.058 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 OAJ23440.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Gtr1_RagA PF04670.12 OAJ23440.1 - 0.28 10.5 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4210 PF13915.6 OAJ23444.1 - 2.4e-22 79.3 0.1 6.2e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAJ23444.1 - 1.8e-12 47.2 0.0 3.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis adh_short PF00106.25 OAJ23444.1 - 5.3e-05 22.8 0.0 0.001 18.5 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase Aldose_epim PF01263.20 OAJ23445.1 - 6.2e-30 104.5 0.0 7.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PRELI PF04707.14 OAJ23446.1 - 1.8e-18 66.8 0.9 3.5e-07 30.2 0.1 3.3 2 1 0 2 2 2 2 PRELI-like family Pkinase PF00069.25 OAJ23447.1 - 9.3e-40 136.6 0.0 8.1e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23447.1 - 2.3e-19 69.7 0.0 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ23447.1 - 1.6e-07 31.0 0.0 6.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAJ23447.1 - 0.063 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family ECH_2 PF16113.5 OAJ23448.1 - 2.9e-76 257.1 1.3 5.7e-73 246.3 1.3 3.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAJ23448.1 - 1.4e-17 63.8 1.9 9.1e-17 61.2 0.1 2.5 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase F-box-like PF12937.7 OAJ23449.1 - 2.8e-08 33.5 0.5 1.6e-07 31.1 0.8 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ23449.1 - 0.021 14.7 0.5 0.077 12.9 0.5 2.0 1 1 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAJ23449.1 - 0.13 12.1 0.1 0.9 9.4 0.0 2.5 3 0 0 3 3 3 0 F-box Urb2 PF10441.9 OAJ23450.1 - 4.9e-40 137.7 1.7 3e-39 135.1 0.0 3.3 3 0 0 3 3 3 1 Urb2/Npa2 family TetR_C_20 PF17925.1 OAJ23450.1 - 0.0028 17.9 0.8 0.037 14.3 0.1 3.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Peptidase_S8 PF00082.22 OAJ23451.1 - 2.9e-43 148.2 0.1 5.6e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ23451.1 - 0.082 13.6 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Fn3-like domain DUF1279 PF06916.13 OAJ23452.1 - 1.5e-14 54.3 0.0 5.5e-14 52.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF4473 PF14747.6 OAJ23452.1 - 0.079 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Sld5 PF05916.11 OAJ23453.1 - 5.5e-05 23.6 0.0 9.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Peptidase_M17 PF00883.21 OAJ23453.1 - 0.039 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain Peptidase_M24_C PF16188.5 OAJ23453.1 - 0.039 14.0 0.2 0.57 10.3 0.0 2.4 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 DMRL_synthase PF00885.19 OAJ23454.1 - 3.3e-52 176.0 0.0 4.2e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase BaffR-Tall_bind PF09256.10 OAJ23454.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding TANGO2 PF05742.12 OAJ23455.1 - 9.6e-06 25.8 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 BCNT PF07572.12 OAJ23456.1 - 6.1e-15 55.0 0.0 1.3e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Bucentaur or craniofacial development DUF1180 PF06679.12 OAJ23456.1 - 3.8 7.9 6.6 3.8 7.9 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Na_Ca_ex PF01699.24 OAJ23457.1 - 1.4e-13 51.1 2.4 1.7e-13 50.8 2.4 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein OATP PF03137.20 OAJ23457.1 - 0.091 11.0 0.6 0.11 10.7 0.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PASTA PF03793.19 OAJ23458.1 - 0.15 12.0 2.6 0.19 11.6 0.9 2.1 2 0 0 2 2 2 0 PASTA domain Transcrip_reg PF01709.20 OAJ23460.1 - 9.5e-60 202.0 0.0 6.1e-59 199.4 0.0 1.9 1 1 0 1 1 1 1 Transcriptional regulator HTH_31 PF13560.6 OAJ23460.1 - 0.032 14.6 0.5 0.34 11.3 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain Spore_III_AB PF09548.10 OAJ23460.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DnaJ PF00226.31 OAJ23461.1 - 6.6e-15 55.0 1.8 1.6e-14 53.8 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain PGM_PMM_I PF02878.16 OAJ23462.1 - 7.6e-22 77.5 0.1 9.3e-12 44.8 0.2 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAJ23462.1 - 6.2e-09 35.9 0.2 1.8e-08 34.4 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OAJ23462.1 - 9.6e-05 22.5 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAJ23462.1 - 0.12 13.0 0.3 3.3 8.4 0.3 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Alg6_Alg8 PF03155.15 OAJ23463.1 - 5.1e-151 503.9 0.5 6e-146 487.2 0.0 2.2 1 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Mitoc_L55 PF09776.9 OAJ23464.1 - 0.26 11.1 2.0 0.39 10.5 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 zf-C2H2 PF00096.26 OAJ23466.1 - 3.4e-10 39.8 11.8 0.012 16.0 0.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ23466.1 - 8.7e-09 35.5 9.4 0.014 16.2 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ23466.1 - 8.5e-08 32.3 13.5 0.0017 18.7 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAJ23466.1 - 7.8e-06 25.8 3.2 0.0013 18.6 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 OAJ23466.1 - 0.0063 16.9 9.3 0.089 13.2 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OAJ23466.1 - 0.09 13.1 4.6 0.29 11.5 3.5 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon Biotin_carb_N PF00289.22 OAJ23466.1 - 0.2 12.2 0.2 0.5 10.9 0.2 1.6 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain zf-C2HC PF01530.18 OAJ23466.1 - 1.5 9.0 7.6 15 5.8 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2HC type zf-C2H2_aberr PF17017.5 OAJ23466.1 - 1.7 8.8 2.9 37 4.4 0.6 2.7 1 1 2 3 3 3 0 Aberrant zinc-finger SIT PF15330.6 OAJ23466.1 - 8.9 6.8 9.7 0.56 10.7 2.8 2.4 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DPBB_1 PF03330.18 OAJ23467.1 - 9.7e-08 32.2 0.2 1.9e-07 31.2 0.1 1.5 1 1 1 2 2 2 1 Lytic transglycolase Barwin PF00967.17 OAJ23467.1 - 0.0017 18.2 0.9 0.0029 17.4 0.9 1.6 1 1 0 1 1 1 1 Barwin family Pro_dh PF01619.18 OAJ23468.1 - 2.7e-51 174.9 0.0 7.6e-32 111.0 0.0 3.1 1 1 1 2 2 2 2 Proline dehydrogenase SET PF00856.28 OAJ23469.1 - 2.6e-15 57.2 0.0 7.1e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 OAJ23469.1 - 3.4e-05 24.4 2.3 3.4e-05 24.4 2.3 1.7 2 0 0 2 2 2 1 Pre-SET motif PPR_2 PF13041.6 OAJ23471.1 - 2.6e-16 59.5 0.3 0.00045 20.4 0.0 4.9 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 OAJ23471.1 - 3.2e-11 43.1 0.0 9.5e-06 25.6 0.0 3.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 OAJ23471.1 - 1.1e-06 28.5 2.4 0.45 10.9 0.1 5.3 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 OAJ23471.1 - 8.3e-06 25.3 0.1 1.2 8.5 0.0 3.8 4 0 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAJ23471.1 - 7.5e-05 22.3 0.1 1.3 8.8 0.0 4.3 4 0 0 4 4 4 2 PPR repeat ATP13 PF12921.7 OAJ23471.1 - 0.00053 19.8 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ATPase expression Na_H_Exchanger PF00999.21 OAJ23472.1 - 3.5e-67 226.8 35.5 4.7e-67 226.4 35.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pex16 PF08610.10 OAJ23473.1 - 6.5e-111 370.6 0.0 1.5e-110 369.4 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) KfrA_N PF11740.8 OAJ23473.1 - 0.16 12.7 1.2 0.31 11.7 0.1 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF2431 PF10354.9 OAJ23474.1 - 3.1e-41 141.5 0.0 4.7e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.6 OAJ23474.1 - 0.075 13.4 0.3 0.075 13.4 0.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 OAJ23474.1 - 0.17 11.9 2.1 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Band_3_cyto PF07565.13 OAJ23474.1 - 0.33 10.7 1.0 0.47 10.2 1.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CN_hydrolase PF00795.22 OAJ23475.1 - 9.2e-19 67.8 0.0 3.5e-14 52.8 0.0 3.0 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase RVT_1 PF00078.27 OAJ23476.1 - 2.2e-12 47.0 0.0 1.3e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ23476.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase LTV PF04180.14 OAJ23478.1 - 1.3e-69 235.8 27.0 1.3e-69 235.8 27.0 1.9 1 1 1 2 2 2 1 Low temperature viability protein Peptidase_C8 PF03569.13 OAJ23478.1 - 0.0078 15.8 0.3 0.017 14.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase family C8 Importin_rep_6 PF18829.1 OAJ23478.1 - 0.49 10.6 3.6 1.5 9.0 3.6 1.8 1 0 0 1 1 1 0 Importin repeat 6 RTC PF01137.21 OAJ23480.1 - 8.8e-51 172.2 0.0 1.1e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OAJ23480.1 - 2.8e-33 114.5 0.0 5e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Zn_clus PF00172.18 OAJ23481.1 - 0.00042 20.4 15.1 0.0006 19.9 15.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 OAJ23487.1 - 1.5e-13 50.0 1.0 0.0021 17.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23487.1 - 4.1e-11 42.1 1.3 0.0076 16.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ23487.1 - 1.5e-07 31.8 0.3 6.1e-05 23.5 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ23487.1 - 6.9e-07 29.4 0.4 1e-06 28.9 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OAJ23487.1 - 0.00011 22.8 0.3 0.057 14.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ23487.1 - 0.0015 18.2 0.2 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 OAJ23487.1 - 0.0019 18.1 0.3 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ23487.1 - 0.0048 17.2 0.7 2 8.8 0.0 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ23487.1 - 0.0062 17.3 3.8 0.51 11.3 2.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ23487.1 - 0.014 15.6 1.2 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HHH_8 PF14716.6 OAJ23487.1 - 0.033 14.6 0.6 5.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_17 PF13431.6 OAJ23487.1 - 0.075 13.5 0.8 1.8 9.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ23487.1 - 0.11 13.2 1.9 23 5.9 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SSF PF00474.17 OAJ23488.1 - 1.4e-12 47.3 25.3 5.4e-12 45.3 25.3 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family RELT PF12606.8 OAJ23489.1 - 1.1 8.3 5.0 42 3.2 5.0 2.3 1 1 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Sod_Fe_C PF02777.18 OAJ23490.1 - 6.3e-34 116.2 1.4 9.2e-34 115.7 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ23490.1 - 7.6e-32 109.6 5.1 1.6e-31 108.6 5.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.6 OAJ23490.1 - 0.05 13.1 0.0 0.21 11.0 0.0 1.9 1 1 1 2 2 2 0 AsmA-like C-terminal region Ribosomal_S19 PF00203.21 OAJ23491.1 - 2.2e-26 91.5 0.0 2.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF1242 PF06842.12 OAJ23492.1 - 1.1e-18 66.7 2.1 1.5e-18 66.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.6 OAJ23492.1 - 0.083 13.2 0.4 0.12 12.7 0.4 1.3 1 0 0 1 1 1 0 Jag N-terminus LST1 PF05083.13 OAJ23492.1 - 0.14 12.4 0.1 0.53 10.6 0.1 1.7 2 0 0 2 2 2 0 LST-1 protein RPN7 PF10602.9 OAJ23493.1 - 5.4e-39 133.7 0.0 1.2e-38 132.5 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAJ23493.1 - 1.3e-12 48.2 0.0 2.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain HORMA PF02301.18 OAJ23494.1 - 1.1e-07 31.6 0.0 2.5e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 HORMA domain Vps54 PF07928.12 OAJ23495.1 - 1.6e-52 177.5 1.6 1.6e-52 177.5 1.6 2.6 2 0 0 2 2 2 1 Vps54-like protein TFIIA PF03153.13 OAJ23495.1 - 9.5e-05 22.6 42.0 9.5e-05 22.6 42.0 2.9 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Vps54_N PF10475.9 OAJ23495.1 - 0.00039 19.8 2.0 0.00039 19.8 2.0 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF4667 PF15700.5 OAJ23495.1 - 0.0015 18.7 2.3 0.0015 18.7 2.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4667) RBM39linker PF15519.6 OAJ23495.1 - 4 8.6 12.2 61 4.8 12.2 3.3 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Inhibitor_I71 PF12628.7 OAJ23495.1 - 6.5 6.6 6.1 2.4e+02 1.5 0.0 2.6 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor SET PF00856.28 OAJ23496.1 - 1e-18 68.3 0.6 5.4e-18 66.0 0.0 2.7 2 0 0 2 2 2 1 SET domain N-SET PF11764.8 OAJ23496.1 - 7.6e-11 42.4 0.8 7.6e-11 42.4 0.8 3.9 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SUIM_assoc PF16619.5 OAJ23496.1 - 0.0008 19.4 2.1 5.6 7.1 0.0 3.9 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 BUD22 PF09073.10 OAJ23496.1 - 0.002 17.5 14.7 0.007 15.8 14.7 1.9 1 0 0 1 1 1 1 BUD22 UCH PF00443.29 OAJ23497.1 - 4.1e-36 124.8 0.0 1.8e-31 109.5 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ23497.1 - 3e-05 23.8 0.0 0.53 9.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase MCM3AP_GANP PF16769.5 OAJ23497.1 - 0.25 9.5 0.7 1.2 7.2 0.1 2.0 2 0 0 2 2 2 0 MCM3AP domain of GANP CSRNP_N PF16019.5 OAJ23497.1 - 0.33 10.8 3.5 1.6 8.6 3.5 2.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus ProRS-C_1 PF09180.11 OAJ23499.1 - 1e-27 96.1 1.8 2e-27 95.2 1.8 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 OAJ23499.1 - 2.4e-16 59.6 0.0 4.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAJ23499.1 - 6.9e-16 58.7 0.0 1.9e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn-ribbon_8 PF09723.10 OAJ23499.1 - 0.23 11.6 1.8 0.97 9.6 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain EzrA PF06160.12 OAJ23499.1 - 0.49 8.5 1.5 0.43 8.7 0.2 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ChAPs PF09295.10 OAJ23500.1 - 1.5e-151 505.0 0.0 3.1e-151 503.9 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 OAJ23500.1 - 0.00014 22.3 0.0 1.5 9.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23500.1 - 0.013 15.6 0.3 6.2 7.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ23500.1 - 0.017 15.3 2.6 4.4 7.6 0.1 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AMP-binding PF00501.28 OAJ23501.1 - 6.4e-88 295.2 0.0 9e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ23501.1 - 3.6e-08 34.3 0.2 8.2e-08 33.1 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SNF2_N PF00176.23 OAJ23502.1 - 2.9e-57 194.0 0.1 4.5e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ23502.1 - 1.2e-16 61.1 0.0 4.2e-16 59.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ23502.1 - 3.9e-09 36.7 0.0 9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ23502.1 - 6.2e-07 28.9 1.8 6.3e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 OAJ23502.1 - 9.6e-05 22.2 0.1 0.00024 20.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HDA2-3 PF11496.8 OAJ23502.1 - 0.016 14.4 0.2 3.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 TrwB_AAD_bind PF10412.9 OAJ23502.1 - 0.55 9.1 4.6 0.28 10.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pkinase PF00069.25 OAJ23503.1 - 3e-56 190.7 0.0 4.1e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23503.1 - 1.5e-28 99.8 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ23503.1 - 4.8e-06 26.1 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ23503.1 - 0.038 13.9 0.1 3.1 7.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ23503.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OAJ23503.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIF1 PF05970.14 OAJ23512.1 - 6.1e-20 71.7 0.0 8.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ23512.1 - 2.3e-14 53.5 0.0 5.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ23512.1 - 2.3e-09 37.8 0.0 7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ23512.1 - 0.0001 22.7 0.5 0.00028 21.3 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ23512.1 - 0.003 17.8 0.0 0.0084 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAJ23512.1 - 0.0043 16.9 1.0 1.5 8.5 0.0 2.6 2 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 OAJ23512.1 - 0.0066 16.0 0.1 0.27 10.7 0.0 2.4 1 1 1 2 2 2 1 P-loop containing dynein motor region Torsin PF06309.11 OAJ23512.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Torsin Sigma54_activat PF00158.26 OAJ23512.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ23512.1 - 0.045 13.7 0.0 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 OAJ23512.1 - 0.075 13.0 0.1 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAJ23512.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OAJ23512.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Croc_4 PF17691.1 OAJ23512.1 - 0.16 12.0 1.4 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Contingent replication of cDNA 4 TPR_1 PF00515.28 OAJ23513.1 - 5.3e-22 76.7 0.5 6.2e-08 32.1 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23513.1 - 1.9e-21 74.4 7.1 4e-06 26.5 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ23513.1 - 7.4e-14 51.3 8.3 0.00016 22.2 0.1 5.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ23513.1 - 2e-13 49.4 1.7 0.0074 16.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ23513.1 - 6.9e-12 44.9 8.8 0.00053 19.6 0.1 5.0 3 1 2 5 5 5 3 TPR repeat TPR_19 PF14559.6 OAJ23513.1 - 1.8e-10 41.2 6.6 0.0015 19.0 0.2 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ23513.1 - 2.1e-09 37.9 7.0 1.5e-05 25.5 0.3 4.6 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ23513.1 - 8.1e-09 35.3 2.6 0.00045 20.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ23513.1 - 2.5e-08 34.1 8.0 0.0032 17.7 2.8 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ23513.1 - 0.0001 22.7 9.1 5.4 7.9 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ23513.1 - 0.00015 21.5 7.7 0.26 11.4 0.0 4.4 6 0 0 6 6 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ23513.1 - 0.00025 21.3 2.3 0.9 9.9 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ23513.1 - 0.0091 16.1 5.0 0.034 14.3 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 OAJ23513.1 - 0.0096 16.4 11.1 0.86 10.0 1.7 4.1 4 0 0 4 4 4 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 OAJ23513.1 - 0.015 15.5 3.6 0.018 15.3 0.4 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAJ23513.1 - 0.031 13.5 3.9 2.9 7.0 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAJ23513.1 - 0.1 12.6 0.5 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ23513.1 - 0.17 11.8 12.8 0.69 9.9 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OAJ23513.1 - 0.74 9.7 4.9 4.5 7.2 0.1 3.2 2 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal CSRNP_N PF16019.5 OAJ23513.1 - 2.8 7.8 5.7 0.19 11.6 0.4 1.6 2 0 0 2 2 1 0 Cysteine/serine-rich nuclear protein N-terminus FUSC PF04632.12 OAJ23514.1 - 0.069 11.7 0.0 0.074 11.6 0.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cyclin_N PF00134.23 OAJ23515.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAJ23515.1 - 0.00019 21.8 0.2 0.00019 21.8 0.2 2.6 2 1 0 2 2 2 1 Cyclin zf-CCCH_2 PF14608.6 OAJ23516.1 - 9.1e-13 48.2 37.6 0.00053 20.4 3.8 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger OSCP PF00213.18 OAJ23517.1 - 6.4e-39 133.8 0.7 7.7e-39 133.6 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Nuc_sug_transp PF04142.15 OAJ23518.1 - 5.4e-66 222.9 6.7 3.3e-49 167.8 1.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 OAJ23518.1 - 0.0012 19.0 8.0 0.0012 19.0 8.0 3.7 2 2 1 3 3 3 1 EamA-like transporter family DUF3439 PF11921.8 OAJ23518.1 - 0.0093 15.9 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) CRT-like PF08627.10 OAJ23518.1 - 0.3 10.0 4.4 0.12 11.3 1.0 1.8 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPR_10 PF13374.6 OAJ23520.1 - 8.9e-06 25.4 4.6 0.086 12.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23520.1 - 0.0005 20.0 0.3 5.9 7.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ23520.1 - 0.0023 18.2 2.3 0.36 11.2 1.4 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat RHH_4 PF13467.6 OAJ23520.1 - 0.027 14.3 0.2 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain Muted PF14942.6 OAJ23520.1 - 0.034 14.5 1.1 0.069 13.5 0.4 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ANAPC5 PF12862.7 OAJ23520.1 - 0.12 12.5 3.9 10 6.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 GST_C_4 PF14834.6 OAJ23521.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HMMR_C PF15908.5 OAJ23521.1 - 0.1 12.8 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Apolipoprotein PF01442.18 OAJ23522.1 - 0.00024 21.1 10.2 0.00056 19.8 9.9 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Cast PF10174.9 OAJ23522.1 - 0.00097 17.5 1.9 0.0012 17.2 1.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF842 PF05811.13 OAJ23522.1 - 0.003 17.2 2.3 0.0049 16.6 2.3 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1664 PF07889.12 OAJ23522.1 - 0.0036 17.3 6.7 0.083 12.9 5.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OAJ23522.1 - 0.0098 15.5 2.9 0.012 15.2 2.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit BORCS6 PF10157.9 OAJ23522.1 - 0.022 15.0 1.1 0.039 14.2 1.1 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 ApoLp-III PF07464.11 OAJ23522.1 - 0.032 14.3 4.6 0.036 14.2 0.4 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OAJ23522.1 - 0.072 13.1 5.4 0.28 11.2 4.4 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atypical_Card PF18461.1 OAJ23522.1 - 0.081 13.2 0.9 0.18 12.1 0.7 1.6 1 1 0 1 1 1 0 Atypical caspase recruitment domain Prominin PF05478.11 OAJ23522.1 - 0.082 10.9 1.8 0.089 10.7 1.8 1.1 1 0 0 1 1 1 0 Prominin V-ATPase_G_2 PF16999.5 OAJ23522.1 - 0.12 12.8 5.3 0.09 13.2 2.5 2.0 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Fzo_mitofusin PF04799.13 OAJ23522.1 - 0.18 11.3 8.3 0.6 9.6 7.7 2.0 1 1 1 2 2 2 0 fzo-like conserved region AKNA PF12443.8 OAJ23522.1 - 1.4 9.7 8.7 1.4 9.6 0.7 3.1 2 1 2 4 4 4 0 AT-hook-containing transcription factor DUF883 PF05957.13 OAJ23522.1 - 3.7 8.2 7.5 3.7 8.2 4.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CENP-T_C PF15511.6 OAJ23524.1 - 8e-10 38.8 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ23524.1 - 0.00096 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ23524.1 - 0.0026 18.1 0.1 0.0044 17.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein PCP_red PF08369.10 OAJ23524.1 - 0.087 13.0 0.3 5.7 7.2 0.0 2.5 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Histone PF00125.24 OAJ23524.1 - 0.09 13.1 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 UPF0137 PF03677.13 OAJ23524.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Bromo_TP PF07524.13 OAJ23524.1 - 0.15 12.0 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PALP PF00291.25 OAJ23526.1 - 9.1e-68 228.8 0.1 1.3e-67 228.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATG13 PF10033.9 OAJ23527.1 - 1.7e-35 122.9 0.0 2.4e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 TBCC PF07986.12 OAJ23530.1 - 2.3e-14 53.2 1.4 4.9e-13 48.9 1.1 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 OAJ23530.1 - 0.0066 16.1 0.5 0.011 15.4 0.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal WD40 PF00400.32 OAJ23531.1 - 1.2e-15 57.6 24.5 0.0026 18.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 OAJ23531.1 - 1.6e-15 57.3 0.0 2.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 OAJ23531.1 - 0.0085 16.4 0.0 16 5.9 0.0 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAJ23531.1 - 0.056 13.9 2.4 1.9 9.1 0.1 4.4 5 0 0 5 5 5 0 PQQ-like domain PhoLip_ATPase_C PF16212.5 OAJ23532.1 - 1.6e-49 168.9 21.2 1.6e-49 168.9 21.2 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ23532.1 - 2.1e-18 65.8 2.9 5.7e-18 64.4 2.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAJ23532.1 - 2.4e-14 54.1 2.1 5.3e-09 36.7 0.6 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ23532.1 - 1.4e-13 50.7 0.9 2.7e-05 23.8 0.2 3.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 OAJ23532.1 - 2e-10 40.6 0.0 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ23532.1 - 0.0022 17.8 0.1 0.0057 16.4 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UBA2_C PF16195.5 OAJ23532.1 - 8 7.2 8.5 0.46 11.2 1.5 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Ribosomal_S6 PF01250.17 OAJ23533.1 - 1.7e-23 82.7 0.0 2.2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 ANAPC4_WD40 PF12894.7 OAJ23534.1 - 1.1e-10 41.7 0.0 9.8e-05 22.6 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ23534.1 - 2.6e-06 28.0 3.6 0.027 15.4 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 OAJ23534.1 - 4e-05 23.4 0.3 0.93 9.5 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat His_Phos_1 PF00300.22 OAJ23535.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_GDSL_2 PF13472.6 OAJ23536.1 - 1.8e-24 87.2 0.0 2.4e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAJ23536.1 - 4.9e-15 56.0 0.0 8e-15 55.3 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CHORD PF04968.12 OAJ23537.1 - 2.9e-41 140.0 14.8 2.3e-21 76.3 4.1 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAJ23537.1 - 2.2e-08 35.0 0.0 3.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 OAJ23537.1 - 0.022 14.6 4.9 0.14 12.0 0.4 2.8 2 0 0 2 2 2 0 BTK motif OppC_N PF12911.7 OAJ23539.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C UQ_con PF00179.26 OAJ23540.1 - 1.5e-17 63.5 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-4CXXC_R1 PF10497.9 OAJ23540.1 - 0.012 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RWD PF05773.22 OAJ23540.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 RWD domain WW_FCH_linker PF16623.5 OAJ23542.1 - 0.13 13.0 0.2 5.7 7.8 0.2 2.0 1 1 1 2 2 2 0 Unstructured linker region between on GAS7 protein Acetyltransf_1 PF00583.25 OAJ23544.1 - 3.1e-14 53.2 0.0 4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ23544.1 - 2.2e-10 40.8 0.0 3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ23544.1 - 1e-09 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ23544.1 - 0.00029 20.8 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAJ23544.1 - 0.0014 19.4 0.0 0.0018 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ23544.1 - 0.0027 17.8 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mastoparan_2 PF08251.11 OAJ23544.1 - 4.6 7.7 4.5 1.2 9.5 0.6 2.1 2 0 0 2 2 2 0 Mastoparan peptide PRIMA1 PF16101.5 OAJ23545.1 - 1.7 8.7 4.9 3.2 7.8 4.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CLTH PF10607.9 OAJ23546.1 - 1.2e-18 67.4 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAJ23546.1 - 0.032 14.2 0.2 0.088 12.8 0.2 1.8 1 0 0 1 1 1 0 LisH FA_hydroxylase PF04116.13 OAJ23549.1 - 1.9e-19 70.4 17.9 1.9e-19 70.4 17.9 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3360 PF11840.8 OAJ23549.1 - 0.14 10.9 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) API5 PF05918.11 OAJ23549.1 - 2.4 6.8 6.1 3.3 6.4 6.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2013 PF09431.10 OAJ23550.1 - 1.5e-53 180.6 2.1 2.8e-53 179.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) RRM_1 PF00076.22 OAJ23551.1 - 2.5e-34 116.9 0.0 7.7e-20 70.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAJ23551.1 - 9.3e-11 42.7 2.1 2.1e-09 38.4 2.1 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAJ23551.1 - 3.1e-06 27.0 0.0 0.036 13.9 0.0 2.9 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAJ23551.1 - 0.00046 19.8 0.0 0.1 12.2 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ23551.1 - 0.0015 18.5 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ23551.1 - 0.018 15.1 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif TEA PF01285.18 OAJ23552.1 - 2.3e-28 98.0 0.0 4.6e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Ribonucleas_3_3 PF14622.6 OAJ23555.1 - 1.7e-20 73.5 0.1 1.7e-20 73.5 0.1 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like TFIIA PF03153.13 OAJ23555.1 - 0.013 15.6 13.2 0.018 15.1 13.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ23555.1 - 0.14 11.8 16.2 0.21 11.2 16.2 1.2 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 OAJ23555.1 - 0.21 11.5 10.2 0.25 11.2 10.2 1.2 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 OAJ23555.1 - 0.41 9.4 9.4 0.61 8.9 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Helicase_RecD PF05127.14 OAJ23555.1 - 1 9.2 3.6 1.9 8.3 3.6 1.5 1 0 0 1 1 1 0 Helicase EPL1 PF10513.9 OAJ23555.1 - 1.1 9.6 6.2 1.6 9.1 6.2 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Hid1 PF12722.7 OAJ23555.1 - 1.1 7.2 5.4 1.4 6.9 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 OAJ23555.1 - 1.4 7.1 16.7 1.7 6.8 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 OAJ23555.1 - 2.7 7.1 9.1 4.2 6.5 9.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.14 OAJ23555.1 - 5.3 6.9 10.9 8 6.3 10.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 OAJ23555.1 - 9.1 7.3 7.1 18 6.4 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Catalase PF00199.19 OAJ23556.1 - 4.1e-168 559.4 0.1 5.4e-168 559.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ23556.1 - 4.4e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DAO PF01266.24 OAJ23557.1 - 5.5e-33 115.0 1.0 2.2e-32 113.0 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ23557.1 - 0.00033 20.8 0.0 0.0013 18.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ23557.1 - 0.033 13.4 0.0 0.56 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OAJ23557.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Mqo PF06039.15 OAJ23557.1 - 0.2 10.2 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) PCI PF01399.27 OAJ23558.1 - 6.3e-13 49.1 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain SSP160 PF06933.11 OAJ23558.1 - 0.033 12.4 2.6 0.044 12.0 2.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Rpn9_C PF18261.1 OAJ23558.1 - 0.051 13.2 0.2 0.092 12.4 0.2 1.4 1 0 0 1 1 1 0 Rpn9 C-terminal helix LRR_9 PF14580.6 OAJ23559.1 - 0.32 10.5 1.5 9.7 5.6 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeat FHA PF00498.26 OAJ23560.1 - 1e-14 54.6 0.0 2.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ23560.1 - 0.0051 17.1 0.9 0.0093 16.3 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain UBA_4 PF14555.6 OAJ23561.1 - 1e-08 34.9 0.2 1.4e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 OAJ23561.1 - 0.018 14.9 8.4 0.39 10.7 1.6 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif HBM PF16591.5 OAJ23561.1 - 0.1 12.0 0.4 1.1 8.7 0.6 2.2 2 0 0 2 2 2 0 Helical bimodular sensor domain Ribosomal_S17 PF00366.20 OAJ23562.1 - 1.8e-20 72.8 0.4 3.1e-20 72.1 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Stealth_CR2 PF11380.8 OAJ23563.1 - 1.8e-16 60.3 0.0 1.3e-05 25.3 0.0 5.2 5 0 0 5 5 5 4 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OAJ23563.1 - 2.3e-05 24.2 0.2 2.3e-05 24.2 0.2 2.5 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 OAJ23563.1 - 0.00018 21.3 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 OAJ23563.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DUF3506 PF12014.8 OAJ23564.1 - 8.6e-12 45.2 0.0 3.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 OAJ23564.1 - 0.00066 19.5 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ23564.1 - 0.014 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain Myb_DNA-bind_3 PF12776.7 OAJ23564.1 - 0.017 16.1 0.0 0.045 14.7 0.0 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HHH_8 PF14716.6 OAJ23564.1 - 0.033 14.6 0.1 0.071 13.5 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Mito_carr PF00153.27 OAJ23565.1 - 5.6e-59 196.1 3.7 1e-21 76.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OAJ23566.1 - 1.8e-50 170.7 0.0 2.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ23566.1 - 1.5e-22 80.1 0.0 2.2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ23566.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ23566.1 - 0.051 13.9 0.6 0.2 12.0 0.6 2.1 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OAJ23566.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CTP_transf_like PF01467.26 OAJ23567.1 - 7.1e-23 81.4 0.0 1.2e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like YL1 PF05764.13 OAJ23567.1 - 0.049 13.7 10.5 0.086 12.9 10.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OAJ23567.1 - 0.081 11.2 10.3 0.11 10.8 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Rota_VP4_MID PF17477.2 OAJ23567.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain SDA1 PF05285.12 OAJ23567.1 - 0.16 11.4 9.8 0.24 10.8 9.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ23567.1 - 0.86 7.7 12.7 1.4 7.1 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 OAJ23567.1 - 2 5.4 7.3 2.8 5.0 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM176 PF14851.6 OAJ23567.1 - 6.5 6.4 11.9 9.1 5.9 9.2 2.3 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 OAJ23567.1 - 6.8 4.7 19.7 11 4.0 19.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAJ23567.1 - 7.2 6.3 23.2 0.74 9.5 17.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein LRR_9 PF14580.6 OAJ23568.1 - 1.8 8.0 4.4 17 4.9 0.2 2.6 2 1 1 3 3 3 0 Leucine-rich repeat S-antigen PF05756.11 OAJ23568.1 - 2.5 8.5 5.0 4.5 7.7 5.0 1.4 1 0 0 1 1 1 0 S-antigen protein ALO PF04030.14 OAJ23569.1 - 1.3e-56 192.3 0.1 2.6e-48 165.1 0.0 2.7 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAJ23569.1 - 6.2e-18 64.9 0.1 1.6e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain HC2 PF07382.11 OAJ23573.1 - 7.8e-14 52.2 73.3 3.6e-13 50.0 46.1 9.9 3 3 5 9 9 9 5 Histone H1-like nucleoprotein HC2 NMT_C PF02799.15 OAJ23574.1 - 1.4e-72 243.6 0.0 3.4e-72 242.3 0.0 1.6 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAJ23574.1 - 8.9e-72 240.1 0.0 1.4e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAJ23574.1 - 0.006 16.6 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ23574.1 - 0.029 14.6 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ23574.1 - 0.18 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IMS PF00817.20 OAJ23575.1 - 4.8e-30 104.5 0.0 9.6e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ23575.1 - 1.4e-05 25.8 0.0 5.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ23575.1 - 0.023 15.0 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Nuf2 PF03800.14 OAJ23575.1 - 0.031 14.4 0.0 0.084 13.0 0.0 1.7 2 0 0 2 2 2 0 Nuf2 family Ank_2 PF12796.7 OAJ23576.1 - 8.9e-15 55.1 0.0 5.8e-07 30.0 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ23576.1 - 1.5e-10 41.4 0.0 1.7e-05 25.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ23576.1 - 9.1e-06 25.9 0.1 0.48 10.8 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ23576.1 - 2.9e-05 24.1 0.0 0.56 10.9 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAJ23576.1 - 0.013 15.9 0.0 28 5.4 0.2 3.5 3 0 0 3 3 3 0 Ankyrin repeat HSCB_C PF07743.13 OAJ23577.1 - 1.4e-18 67.2 0.6 1.4e-18 67.2 0.6 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAJ23577.1 - 2.6e-06 27.4 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain cwf21 PF08312.12 OAJ23577.1 - 0.017 15.3 1.1 0.043 14.0 1.1 1.7 1 0 0 1 1 1 0 cwf21 domain EF-hand_1 PF00036.32 OAJ23578.1 - 5.9e-28 94.3 13.7 5.9e-08 31.7 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OAJ23578.1 - 6.6e-22 75.5 8.6 3.7e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OAJ23578.1 - 2.9e-21 75.7 8.7 1.1e-12 48.2 2.6 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ23578.1 - 5.7e-18 63.5 15.2 8e-06 25.1 1.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OAJ23578.1 - 3.1e-12 46.2 15.8 0.0063 16.3 1.6 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAJ23578.1 - 2.6e-05 24.5 0.0 0.046 14.0 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAJ23578.1 - 0.00023 21.1 6.7 0.0091 15.9 0.8 3.6 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAJ23578.1 - 0.0009 19.5 0.1 0.62 10.4 0.2 3.1 2 1 1 3 3 3 1 EF-hand domain Nse4-Nse3_bdg PF15412.6 OAJ23578.1 - 0.06 13.5 0.5 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE RTA1 PF04479.13 OAJ23579.1 - 7.5e-43 146.5 7.8 7.5e-43 146.5 7.8 1.7 1 1 1 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.21 OAJ23579.1 - 0.015 15.0 10.8 1.1 8.9 10.8 2.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Syndecan PF01034.20 OAJ23579.1 - 2.7 8.0 8.3 1.4 8.9 0.1 3.0 3 0 0 3 3 3 0 Syndecan domain LapA_dom PF06305.11 OAJ23579.1 - 5.6 6.9 6.2 2.9 7.8 0.2 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SelR PF01641.18 OAJ23580.1 - 1.7e-50 170.2 0.1 2.3e-50 169.7 0.1 1.2 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 OAJ23580.1 - 0.1 12.7 2.4 0.14 12.3 0.3 2.3 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Dicty_REP PF05086.12 OAJ23580.1 - 1.5 6.7 2.7 1.7 6.5 2.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TSGP1 PF07771.11 OAJ23581.1 - 0.3 11.2 5.8 1.2 9.3 0.1 3.3 3 1 0 3 3 3 0 Tick salivary peptide group 1 Prenyltransf PF01255.19 OAJ23582.1 - 3.2e-72 242.7 0.0 4.2e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rer1 PF03248.13 OAJ23582.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Rer1 family CX9C PF16860.5 OAJ23583.1 - 0.00092 19.2 3.2 0.31 11.1 0.4 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 OAJ23583.1 - 0.079 13.2 0.5 0.16 12.3 0.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 OAJ23583.1 - 0.09 12.8 1.5 0.46 10.5 2.0 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rhodanese PF00581.20 OAJ23585.1 - 1.2e-12 48.3 0.0 2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Spt20 PF12090.8 OAJ23586.1 - 0.13 11.8 11.0 0.21 11.2 11.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF3292 PF11696.8 OAJ23586.1 - 1.1 7.6 5.0 1.5 7.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TFIIA PF03153.13 OAJ23586.1 - 1.3 8.9 23.4 1.6 8.6 23.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 OAJ23586.1 - 8.6 5.3 6.4 12 4.8 6.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein MFS_1 PF07690.16 OAJ23587.1 - 6.4e-29 101.0 25.9 6.4e-29 101.0 25.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ23587.1 - 2e-19 69.8 17.0 1.2e-18 67.2 4.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAJ23587.1 - 0.032 13.1 7.0 0.016 14.1 1.6 2.8 2 1 0 2 2 2 0 MFS_1 like family Ribosomal_S13 PF00416.22 OAJ23588.1 - 4.9e-21 75.5 0.0 3.2e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 OAJ23588.1 - 0.0029 16.4 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Abhydrolase_3 PF07859.13 OAJ23589.1 - 1.1e-14 54.8 0.0 1.5e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ23589.1 - 3.1e-06 26.8 0.0 3.4e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 OAJ23589.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF5423 PF17461.2 OAJ23589.1 - 0.28 10.0 3.0 0.43 9.4 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) CSN8_PSD8_EIF3K PF10075.9 OAJ23590.1 - 5.4e-30 104.3 0.0 8.4e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OAJ23590.1 - 1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Nup188 PF10487.9 OAJ23591.1 - 5.6e-24 84.2 0.0 4e-11 41.6 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Rhodanese PF00581.20 OAJ23592.1 - 1.4e-12 48.0 0.0 5.9e-12 46.1 0.0 1.9 1 1 1 2 2 2 1 Rhodanese-like domain Oxysterol_BP PF01237.18 OAJ23593.1 - 3.8e-18 65.5 0.0 4.9e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein UL73_N PF12522.8 OAJ23593.1 - 0.27 11.0 3.0 0.29 10.9 1.5 2.0 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Proteasome PF00227.26 OAJ23595.1 - 3.8e-39 134.2 0.0 4.3e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glyco_transf_8 PF01501.20 OAJ23598.1 - 1.2e-18 67.7 0.0 9.8e-16 58.1 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAJ23598.1 - 0.038 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Thiol_cytolysin PF01289.19 OAJ23598.1 - 0.2 10.5 0.0 0.4 9.5 0.0 1.4 1 0 0 1 1 1 0 Thiol-activated cytolysin MFS_1 PF07690.16 OAJ23599.1 - 2.8e-16 59.4 43.0 2.8e-16 59.4 43.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily CDT1_C PF16679.5 OAJ23600.1 - 2.3e-14 53.6 2.4 9.4e-12 45.2 0.1 3.3 2 1 0 2 2 2 2 DNA replication factor Cdt1 C-terminal domain She9_MDM33 PF05546.11 OAJ23601.1 - 0.028 14.2 0.4 0.2 11.5 0.3 2.0 2 0 0 2 2 2 0 She9 / Mdm33 family DUF2884 PF11101.8 OAJ23601.1 - 0.18 11.3 0.2 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Mating_N PF12731.7 OAJ23601.1 - 0.23 11.6 2.5 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 Nodulin_late PF07127.11 OAJ23602.1 - 0.2 12.0 2.5 2.2 8.7 0.1 2.6 3 0 0 3 3 3 0 Late nodulin protein Pyrid_ox_like PF16242.5 OAJ23603.1 - 2.5e-29 101.8 0.2 4.1e-29 101.1 0.2 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAJ23603.1 - 3.4e-11 43.2 0.0 1.6e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF374 PF04028.13 OAJ23603.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) eIF-5_eIF-2B PF01873.17 OAJ23604.1 - 5.6e-40 135.9 0.3 9.1e-40 135.2 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OAJ23604.1 - 0.00051 19.5 0.2 0.00086 18.8 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Bclt PF15318.6 OAJ23604.1 - 0.25 11.2 5.3 0.089 12.6 2.3 1.9 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis Arc_trans_TRASH PF08394.10 OAJ23604.1 - 8.1 6.9 12.2 0.54 10.6 0.2 2.8 2 1 1 3 3 3 0 Archaeal TRASH domain PITH PF06201.13 OAJ23605.1 - 1.2e-35 122.9 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain ATP-synt PF00231.19 OAJ23606.1 - 1.8e-64 218.2 1.4 2e-64 218.0 1.4 1.0 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.10 OAJ23606.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain ATP-synt PF00231.19 OAJ23607.1 - 1.2e-10 41.6 7.2 1.7e-10 41.1 7.1 1.4 1 1 0 1 1 1 1 ATP synthase NOP5NT PF08156.13 OAJ23607.1 - 0.069 13.5 0.5 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 NOP5NT (NUC127) domain DUF4404 PF14357.6 OAJ23607.1 - 0.37 11.5 2.4 11 6.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Myb_DNA-bind_4 PF13837.6 OAJ23608.1 - 9e-05 22.8 0.2 9e-05 22.8 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Neur_chan_memb PF02932.16 OAJ23608.1 - 1.6 8.7 3.3 1 9.4 0.8 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DDE_Tnp_4 PF13359.6 OAJ23609.1 - 2.3e-23 82.6 0.0 4.4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease LSM PF01423.22 OAJ23610.1 - 1.1e-15 57.1 0.0 1.9e-15 56.3 0.0 1.4 2 0 0 2 2 2 1 LSM domain DUF3510 PF12022.8 OAJ23610.1 - 0.0044 17.4 0.0 0.0053 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) GRP PF07172.11 OAJ23610.1 - 2.6 8.8 28.4 3.8 8.3 28.4 1.2 1 0 0 1 1 1 0 Glycine rich protein family CRAL_TRIO PF00650.20 OAJ23611.1 - 6e-29 100.8 0.0 9.1e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAJ23611.1 - 2.4e-08 34.2 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ23611.1 - 1.8e-07 31.2 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Cation_efflux PF01545.21 OAJ23612.1 - 3.5e-16 59.5 2.3 4.4e-16 59.2 2.3 1.1 1 0 0 1 1 1 1 Cation efflux family SKI PF01202.22 OAJ23613.1 - 1.3e-05 25.3 0.2 0.0006 20.0 0.0 2.5 2 1 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 OAJ23613.1 - 1.9e-05 25.2 1.6 0.0076 16.8 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAJ23613.1 - 0.00028 21.1 0.2 0.033 14.4 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAJ23613.1 - 0.0016 18.1 0.7 0.0031 17.1 0.2 1.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ23613.1 - 0.0077 16.5 1.7 0.015 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 OAJ23613.1 - 0.023 14.6 0.3 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 OAJ23613.1 - 0.024 14.3 0.0 0.045 13.5 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase APS_kinase PF01583.20 OAJ23613.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 OAJ23613.1 - 0.15 11.8 0.4 0.3 10.9 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.6 OAJ23613.1 - 0.21 11.7 2.3 0.64 10.1 0.0 2.4 2 1 0 3 3 3 0 Cytidylate kinase-like family IstB_IS21 PF01695.17 OAJ23613.1 - 0.73 9.5 1.9 0.69 9.6 0.2 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF305 PF03713.13 OAJ23613.1 - 1 9.5 4.0 0.26 11.4 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF305) AAA_16 PF13191.6 OAJ23613.1 - 1 9.7 3.2 1.3 9.4 1.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain Synaptobrevin PF00957.21 OAJ23616.1 - 0.99 9.2 2.4 2.2 8.1 2.4 1.7 1 0 0 1 1 1 0 Synaptobrevin Cutinase PF01083.22 OAJ23619.1 - 6.6e-23 81.6 0.2 8e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ23619.1 - 0.057 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain F-box-like PF12937.7 OAJ23624.1 - 4.5e-10 39.3 0.8 1.5e-09 37.6 0.8 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ23624.1 - 9.2e-06 25.4 0.9 2.7e-05 23.9 0.9 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 OAJ23624.1 - 0.022 15.6 1.1 0.57 11.2 0.2 3.3 3 1 0 3 3 3 0 WD domain, G-beta repeat Phage_integrase PF00589.22 OAJ23625.1 - 0.024 14.5 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family Zn_clus PF00172.18 OAJ23626.1 - 4.2e-06 26.8 11.3 6.8e-06 26.1 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.13 OAJ23626.1 - 1.9 8.5 5.5 2 8.5 2.6 2.0 2 0 0 2 2 2 0 YL1 nuclear protein F-box PF00646.33 OAJ23627.1 - 1.4e-07 31.2 0.1 3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ23627.1 - 0.0028 17.5 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ23627.1 - 0.029 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box Peroxin-3 PF04882.12 OAJ23629.1 - 2.5e-109 366.4 19.5 6.2e-106 355.2 19.5 2.2 1 1 0 1 1 1 1 Peroxin-3 Acyltransferase PF01553.21 OAJ23630.1 - 1.9e-20 72.8 0.0 5.1e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase ELL PF10390.9 OAJ23630.1 - 0.014 14.9 2.2 0.022 14.2 2.2 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL SR-25 PF10500.9 OAJ23630.1 - 0.47 10.0 7.8 0.84 9.2 7.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 OAJ23631.1 - 1.3e-11 44.5 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIN3 PF04873.13 OAJ23631.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethylene insensitive 3 ATP-synt_E PF05680.12 OAJ23632.1 - 6.3e-21 74.5 0.1 7e-21 74.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain LdpA_C PF12617.8 OAJ23632.1 - 0.15 11.7 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Complex1_30kDa PF00329.19 OAJ23633.1 - 6.1e-46 156.0 0.0 8.3e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Pkinase PF00069.25 OAJ23634.1 - 7.1e-35 120.6 0.0 1.8e-34 119.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23634.1 - 1.5e-19 70.3 0.0 2.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ23634.1 - 0.28 9.9 0.0 0.47 9.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NAD_Gly3P_dh_C PF07479.14 OAJ23635.1 - 8.8e-47 159.0 0.1 2e-46 157.8 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OAJ23635.1 - 9.3e-47 158.9 0.0 3.5e-46 157.0 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OAJ23635.1 - 1.9e-05 25.2 0.7 0.00056 20.4 0.7 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OAJ23635.1 - 0.0051 16.4 0.4 0.58 9.7 0.0 2.4 1 1 1 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain Na_H_Exchanger PF00999.21 OAJ23636.1 - 1.4e-65 221.6 22.8 1.8e-65 221.2 22.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3811 PF11656.8 OAJ23636.1 - 0.031 14.7 1.0 0.088 13.2 1.0 1.7 1 0 0 1 1 1 0 YjbD family (DUF3811) YrhC PF14143.6 OAJ23636.1 - 0.11 12.6 1.1 0.38 10.9 1.1 1.9 1 0 0 1 1 1 0 YrhC-like protein SCP2 PF02036.17 OAJ23638.1 - 6.4e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ23638.1 - 0.0029 17.9 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 OAJ23638.1 - 0.0091 16.4 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 Sterol carrier protein domain SCP_3 PF17844.1 OAJ23638.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial SCP ortholog Pro_isomerase PF00160.21 OAJ23639.1 - 1.4e-42 145.7 0.3 9.1e-42 143.0 0.3 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_47 PF01532.20 OAJ23640.1 - 9.1e-118 394.0 0.1 1.1e-117 393.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Bot1p PF12298.8 OAJ23641.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Perilipin PF03036.16 OAJ23642.1 - 1.2e-06 27.9 0.6 0.00027 20.1 0.0 2.6 1 1 2 3 3 3 2 Perilipin family ApoLp-III PF07464.11 OAJ23642.1 - 0.16 12.1 2.2 0.26 11.4 1.2 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 OAJ23642.1 - 0.19 11.6 2.5 0.44 10.4 2.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 OAJ23642.1 - 0.37 11.4 1.7 0.74 10.4 1.0 1.8 2 0 0 2 2 2 0 YtxH-like protein DUF1958 PF09211.10 OAJ23643.1 - 0.056 13.8 0.0 0.08 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) adh_short PF00106.25 OAJ23646.1 - 1.5e-05 24.5 0.0 0.066 12.7 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase AAA_6 PF12774.7 OAJ23647.1 - 2.8e-130 434.1 0.0 1.5e-129 431.7 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OAJ23647.1 - 5.5e-115 384.6 6.1 5.5e-115 384.6 6.1 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OAJ23647.1 - 3.1e-109 366.2 11.7 3.1e-109 366.2 11.7 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 OAJ23647.1 - 1.7e-42 145.0 0.0 3.5e-36 124.4 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 OAJ23647.1 - 1.1e-40 139.6 0.0 4.3e-40 137.7 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 OAJ23647.1 - 1.3e-27 96.5 0.0 4.3e-13 49.4 0.0 6.1 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OAJ23647.1 - 1e-14 54.7 0.0 3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OAJ23647.1 - 7e-14 52.3 0.3 0.0055 17.0 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 OAJ23647.1 - 7.5e-14 52.3 0.0 0.0068 16.8 0.0 5.3 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ23647.1 - 4.2e-10 40.3 1.8 0.073 13.5 0.2 6.5 5 1 0 6 6 5 2 AAA ATPase domain AAA_33 PF13671.6 OAJ23647.1 - 1.3e-09 38.3 0.0 0.12 12.6 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAJ23647.1 - 1.4e-07 32.2 0.0 1.5 9.4 0.0 4.9 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 OAJ23647.1 - 3.3e-07 29.6 0.0 0.0053 15.9 0.0 3.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 OAJ23647.1 - 6e-06 26.1 0.8 4.3 7.0 0.0 4.7 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 OAJ23647.1 - 4.7e-05 22.9 2.9 0.59 9.5 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ23647.1 - 0.00021 21.1 0.7 0.71 9.6 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 OAJ23647.1 - 0.00066 20.0 8.5 0.28 11.5 0.0 5.6 6 1 1 7 7 5 1 AAA domain AAA_lid_1 PF17857.1 OAJ23647.1 - 0.00069 19.8 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 OAJ23647.1 - 0.0034 17.1 0.1 9.2 6.1 0.0 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rad17 PF03215.15 OAJ23647.1 - 0.0035 17.3 0.1 23 4.8 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_24 PF13479.6 OAJ23647.1 - 0.0074 16.0 0.3 20 4.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 OAJ23647.1 - 0.012 15.1 0.0 0.54 9.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAJ23647.1 - 0.017 15.5 0.0 18 5.7 0.0 4.3 4 0 0 4 4 4 0 RNA helicase AAA_11 PF13086.6 OAJ23647.1 - 0.021 14.6 1.9 1.2 8.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ23647.1 - 0.023 14.1 0.0 18 4.6 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 OAJ23647.1 - 0.027 15.0 3.9 62 4.1 0.0 5.1 5 0 0 5 5 4 0 ABC transporter RuvB_N PF05496.12 OAJ23647.1 - 0.042 13.6 0.2 4.2 7.1 0.0 3.6 4 0 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 OAJ23647.1 - 0.41 10.2 1.3 51 3.4 0.0 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF148 PF02520.17 OAJ23647.1 - 4.7 7.4 8.2 3.7 7.7 2.5 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF1664 PF07889.12 OAJ23647.1 - 5 7.2 5.8 19 5.3 0.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) CRC_subunit PF08624.10 OAJ23648.1 - 9.8e-39 132.9 0.0 1.7e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TFIIA PF03153.13 OAJ23648.1 - 0.23 11.4 24.0 0.35 10.8 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.9 OAJ23651.1 - 2.1e-08 34.1 0.0 2.8e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase ESSS PF10183.9 OAJ23651.1 - 0.12 12.6 0.2 0.37 11.0 0.2 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NUP214 PF16755.5 OAJ23652.1 - 3.6e-05 23.2 0.0 0.00031 20.1 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 RVT_1 PF00078.27 OAJ23654.1 - 4.6e-28 98.2 0.0 6.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ23654.1 - 1.1e-16 60.8 0.6 3.6e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase VESA1_N PF12785.7 OAJ23655.1 - 0.17 10.8 9.6 0.23 10.4 9.6 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 zf-CCHC PF00098.23 OAJ23655.1 - 0.64 10.2 9.0 0.069 13.3 2.5 2.6 2 0 0 2 2 2 0 Zinc knuckle Sad1_UNC PF07738.13 OAJ23656.1 - 3.5e-13 49.7 0.0 1.7e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Chordopox_A30L PF06015.12 OAJ23656.1 - 0.055 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A30L protein RPAP1_N PF08621.10 OAJ23657.1 - 2.3e-07 30.5 1.5 4.8e-07 29.4 1.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 OAJ23657.1 - 0.011 15.8 1.6 0.063 13.4 1.6 2.3 1 1 0 1 1 1 0 RPAP1-like, C-terminal YdaT_toxin PF06254.11 OAJ23657.1 - 0.12 13.0 0.1 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Putative bacterial toxin ydaT FlxA PF14282.6 OAJ23657.1 - 1.7 8.6 6.4 7.1 6.7 6.4 2.0 1 0 0 1 1 1 0 FlxA-like protein Maf1 PF09174.10 OAJ23658.1 - 2e-29 102.9 0.0 6.5e-18 65.5 0.0 3.5 3 0 0 3 3 3 3 Maf1 regulator DUF1749 PF08538.10 OAJ23660.1 - 0.00041 19.5 0.0 0.00059 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 OAJ23660.1 - 0.033 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 OAJ23660.1 - 0.051 13.1 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.12 OAJ23660.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 OAJ23660.1 - 0.15 11.3 0.0 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zf-rbx1 PF12678.7 OAJ23661.1 - 2e-25 88.8 12.4 3.2e-25 88.2 12.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ23661.1 - 1.4e-17 63.5 11.9 1.9e-17 63.1 11.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAJ23661.1 - 1e-06 29.0 16.7 9.6e-05 22.6 16.7 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ23661.1 - 1.5e-05 24.8 3.0 1.5e-05 24.8 3.0 2.4 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ23661.1 - 0.00033 20.5 10.7 0.0036 17.1 10.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ23661.1 - 0.0097 15.8 10.0 0.097 12.6 3.6 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ23661.1 - 0.17 11.5 14.6 0.063 12.9 4.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAJ23661.1 - 3 7.9 11.7 0.8 9.8 7.7 2.2 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 OAJ23661.1 - 3.2 8.0 16.5 0.2 11.8 9.3 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OAJ23661.1 - 3.2 7.6 20.4 49 3.8 17.3 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 OAJ23661.1 - 4 7.5 11.9 20 5.2 11.9 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Pkinase_Tyr PF07714.17 OAJ23667.1 - 7.8e-09 35.2 0.0 8.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ23667.1 - 8e-09 35.2 0.0 7.6e-06 25.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 OAJ23667.1 - 0.0012 18.8 0.2 0.002 18.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ23667.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OAJ23667.1 - 0.11 11.9 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_Tnp_4 PF13359.6 OAJ23668.1 - 6.4e-22 77.9 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ23668.1 - 7.7e-05 22.4 3.0 0.00051 19.7 0.2 2.7 2 1 0 2 2 2 1 Transposase DDE domain API5 PF05918.11 OAJ23668.1 - 6.4 5.5 7.5 9.6 4.9 7.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4718 PF15842.5 OAJ23670.1 - 1.9 8.3 6.2 1.7 8.4 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) HRG PF16954.5 OAJ23671.1 - 0.0044 17.4 3.2 0.033 14.6 0.1 2.9 2 0 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene Wzy_C PF04932.15 OAJ23671.1 - 0.011 15.3 1.6 0.15 11.7 0.1 2.5 2 0 0 2 2 2 0 O-Antigen ligase ATG27 PF09451.10 OAJ23671.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Pneumo_M2 PF07380.11 OAJ23673.1 - 0.18 12.1 0.9 0.27 11.5 0.9 1.3 1 0 0 1 1 1 0 Pneumovirus M2 protein SecA_SW PF07516.13 OAJ23674.1 - 0.039 14.0 5.6 0.091 12.8 2.0 2.7 2 1 0 2 2 2 0 SecA Wing and Scaffold domain CR6_interact PF10147.9 OAJ23674.1 - 0.066 12.9 0.4 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ribosomal_S14 PF00253.21 OAJ23676.1 - 2.9e-21 75.0 0.2 4.9e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e QLQ PF08880.11 OAJ23676.1 - 0.026 14.3 0.9 0.065 13.0 0.1 2.1 2 1 0 2 2 2 0 QLQ RNA_pol_Rpb6 PF01192.22 OAJ23677.1 - 7e-16 57.9 0.1 9.8e-16 57.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pkinase PF00069.25 OAJ23678.1 - 1.9e-46 158.6 0.0 3.6e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23678.1 - 5.2e-25 88.2 0.0 8.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ23678.1 - 0.0047 16.9 0.3 0.018 14.9 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ23678.1 - 0.04 12.8 0.2 0.078 11.9 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OAJ23678.1 - 0.049 12.9 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OAJ23678.1 - 0.16 11.6 0.2 6.4 6.3 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 OAJ23680.1 - 1.6e-59 201.3 2.1 2e-59 201.0 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ23680.1 - 4.4e-44 150.3 1.0 5.8e-44 149.9 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ23680.1 - 1.5e-10 41.2 0.2 2.4e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAJ23680.1 - 0.025 15.2 0.3 0.051 14.2 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAJ23680.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OAJ23680.1 - 0.054 12.9 0.1 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PATR PF12951.7 OAJ23680.1 - 0.13 12.4 0.9 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Passenger-associated-transport-repeat HATPase_c PF02518.26 OAJ23680.1 - 0.16 12.5 0.0 0.42 11.1 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med7 PF05983.11 OAJ23681.1 - 2.7e-41 141.8 1.0 6.8e-41 140.5 1.0 1.6 1 1 0 1 1 1 1 MED7 protein FapA PF03961.13 OAJ23681.1 - 0.031 12.9 0.2 0.043 12.4 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FdhE PF04216.12 OAJ23681.1 - 0.052 13.4 0.4 0.07 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation FlaC_arch PF05377.11 OAJ23681.1 - 0.079 13.4 0.4 6 7.3 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliT PF05400.13 OAJ23681.1 - 0.62 10.9 6.6 1 10.2 5.5 1.8 2 0 0 2 2 2 0 Flagellar protein FliT Ribosomal_L12 PF00542.19 OAJ23683.1 - 2.2e-20 72.7 8.3 9.1e-20 70.8 5.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OAJ23683.1 - 3.9e-12 45.7 7.0 3.9e-12 45.7 7.0 4.6 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Tautomerase_3 PF14832.6 OAJ23685.1 - 3.4e-37 127.7 0.0 4e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme RIBIOP_C PF04950.12 OAJ23688.1 - 8.9e-102 340.4 0.0 1.3e-101 339.9 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAJ23688.1 - 3.5e-22 78.3 0.0 1e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain E1_DerP2_DerF2 PF02221.15 OAJ23691.1 - 6.5e-27 94.6 0.0 8.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 ML domain YTH PF04146.15 OAJ23692.1 - 2.4e-52 177.2 0.0 2.4e-52 177.2 0.0 3.6 2 2 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 OAJ23692.1 - 0.0032 17.2 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaredoxin PF00462.24 OAJ23693.1 - 1.2e-18 67.1 0.0 8.2e-18 64.4 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAJ23693.1 - 2e-15 56.6 0.0 3.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ23693.1 - 0.0001 22.6 0.0 0.089 13.1 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ23693.1 - 0.00076 19.9 0.0 0.0055 17.1 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 OAJ23693.1 - 0.0033 17.4 0.0 0.014 15.4 0.0 2.0 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DUF726 PF05277.12 OAJ23694.1 - 5.6e-35 120.9 15.9 2.2e-26 92.6 10.0 3.6 2 2 0 2 2 2 2 Protein of unknown function (DUF726) Ser_hydrolase PF06821.13 OAJ23694.1 - 0.00056 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 OAJ23694.1 - 0.019 15.6 0.1 0.019 15.6 0.1 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family DUF900 PF05990.12 OAJ23694.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 OAJ23694.1 - 0.16 11.1 0.1 0.37 9.9 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase CoA_transf_3 PF02515.17 OAJ23695.1 - 8.2e-126 420.0 0.0 1e-125 419.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF1729 PF08354.10 OAJ23696.1 - 6.8e-20 71.3 0.0 8.8e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) F-box PF00646.33 OAJ23696.1 - 2e-07 30.7 1.0 4.7e-07 29.5 0.5 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ23696.1 - 0.00017 21.4 0.7 0.00049 19.9 0.4 1.9 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OAJ23696.1 - 0.098 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 F-box Galactosyl_T PF01762.21 OAJ23699.1 - 1.7e-12 47.6 0.4 3e-07 30.5 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase T3SSipB PF16535.5 OAJ23700.1 - 0.039 14.4 0.2 0.039 14.4 0.2 2.8 4 0 0 4 4 4 0 Type III cell invasion protein SipB Use1 PF09753.9 OAJ23701.1 - 6.3e-09 35.9 0.0 7.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 ANXA2R PF15721.5 OAJ23701.1 - 0.022 15.3 2.6 0.035 14.6 2.6 1.3 1 0 0 1 1 1 0 Annexin-2 receptor EF-hand_1 PF00036.32 OAJ23702.1 - 1.8e-25 86.5 7.6 2.5e-08 32.9 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 OAJ23702.1 - 4.2e-25 88.0 5.0 2.4e-15 56.7 1.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAJ23702.1 - 2.4e-21 73.8 4.0 1.5e-06 27.7 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ23702.1 - 2e-12 46.8 5.3 0.00034 20.4 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAJ23702.1 - 1.1e-10 40.5 11.6 0.00013 21.3 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 OAJ23702.1 - 7.6e-10 38.7 6.0 0.00097 19.1 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAJ23702.1 - 5.1e-06 26.7 0.9 0.00032 21.0 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OAJ23702.1 - 0.023 15.0 2.5 1.5 9.1 0.2 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OAJ23702.1 - 1 9.2 4.4 18 5.2 0.1 3.2 2 1 1 3 3 3 0 Caleosin related protein Abhydrolase_1 PF00561.20 OAJ23703.1 - 1.3e-08 34.8 0.0 1.5e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold zf-C2H2 PF00096.26 OAJ23705.1 - 1.2e-08 34.9 13.0 0.00093 19.5 2.1 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ23705.1 - 7.4e-08 32.5 17.0 0.00021 21.6 4.3 4.0 3 0 0 3 3 3 3 Zinc-finger double domain HsbA PF12296.8 OAJ23706.1 - 4.1e-14 53.0 3.5 4.1e-14 53.0 3.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A CheZ PF04344.13 OAJ23706.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF2969 PF11184.8 OAJ23706.1 - 0.043 14.2 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) Helicase_C PF00271.31 OAJ23707.1 - 2e-12 47.4 0.0 5.7e-12 46.0 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ23707.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAJ23707.1 - 0.047 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase OrfB_IS605 PF01385.19 OAJ23709.1 - 0.00068 19.9 7.0 0.0088 16.3 0.6 3.0 1 1 1 2 2 2 2 Probable transposase adh_short PF00106.25 OAJ23714.1 - 0.0013 18.2 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ23714.1 - 0.0062 16.1 0.1 0.0093 15.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PEHE PF15275.6 OAJ23715.1 - 0.15 12.6 2.5 0.17 12.5 2.5 1.1 1 0 0 1 1 1 0 PEHE domain DUF3099 PF11298.8 OAJ23715.1 - 5.5 7.2 0.0 5.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Helitron_like_N PF14214.6 OAJ23717.1 - 4.7e-24 85.7 0.0 1.3e-23 84.3 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ23717.1 - 1.2e-20 74.0 0.1 3.9e-20 72.3 0.1 1.8 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ23717.1 - 1.1e-13 51.4 0.7 3.1e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ23717.1 - 1.5e-08 35.1 0.3 7.9e-07 29.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OAJ23717.1 - 0.0028 18.0 0.0 0.0095 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF4164 PF13747.6 OAJ23718.1 - 0.026 14.8 4.1 0.074 13.3 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.13 OAJ23718.1 - 0.11 12.1 1.9 0.16 11.5 1.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF1043 PF06295.12 OAJ23718.1 - 0.15 12.1 1.3 0.21 11.6 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Apolipoprotein PF01442.18 OAJ23718.1 - 0.15 11.9 7.1 0.31 10.9 7.2 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.13 OAJ23718.1 - 0.17 12.4 2.3 0.24 11.9 1.0 1.9 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ArsA_HSP20 PF17886.1 OAJ23719.1 - 0.077 12.6 0.0 21 4.8 0.0 3.1 3 0 0 3 3 3 0 HSP20-like domain found in ArsA H_lectin PF09458.10 OAJ23720.1 - 5.7e-07 29.6 0.0 2.1e-05 24.6 0.0 2.9 2 0 0 2 2 2 1 H-type lectin domain RNase_PH_C PF03725.15 OAJ23720.1 - 0.012 15.7 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF948 PF06103.11 OAJ23721.1 - 0.42 10.9 5.9 7.1 7.0 0.8 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TRAF_BIRC3_bd PF16673.5 OAJ23721.1 - 4.6 7.1 10.9 0.13 12.0 2.3 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Jacalin PF01419.17 OAJ23722.1 - 0.0006 19.7 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Jacalin PF01419.17 OAJ23723.1 - 1.7e-07 31.2 0.0 0.00014 21.8 0.0 2.7 2 1 0 2 2 2 2 Jacalin-like lectin domain TraV PF09676.10 OAJ23727.1 - 1.1 10.2 5.2 1 10.4 4.3 1.3 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) JCAD PF15351.6 OAJ23728.1 - 0.12 10.2 0.5 0.16 9.7 0.5 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Histone_H2A_C PF16211.5 OAJ23729.1 - 2.1e-18 65.7 0.8 4.8e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ23729.1 - 9.9e-12 45.4 0.0 1.6e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MFS_1 PF07690.16 OAJ23730.1 - 1.3e-40 139.4 27.4 1e-36 126.6 9.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ23730.1 - 4e-09 35.9 1.4 4e-09 35.9 1.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter UPF0242 PF06785.11 OAJ23730.1 - 0.049 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COX2-transmemb PF09125.10 OAJ23730.1 - 0.39 10.5 0.0 0.39 10.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane OATP PF03137.20 OAJ23730.1 - 0.61 8.3 12.4 0.021 13.2 2.3 3.1 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PALP PF00291.25 OAJ23732.1 - 2.7e-79 266.7 0.1 2.7e-79 266.7 0.1 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAJ23732.1 - 3.7e-07 29.8 0.0 0.00017 21.3 0.0 3.0 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase DUF3818 PF12825.7 OAJ23736.1 - 9.9e-46 156.3 0.0 1.3e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ23736.1 - 3.8e-27 94.8 0.0 6.8e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 PX-associated NicO PF03824.16 OAJ23737.1 - 4e-31 108.4 9.4 4.2e-14 52.6 0.0 5.0 4 1 1 5 5 5 3 High-affinity nickel-transport protein TRP PF06011.12 OAJ23737.1 - 0.0016 17.2 0.0 0.0025 16.6 0.0 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel PDGLE PF13190.6 OAJ23737.1 - 0.21 11.5 2.0 0.37 10.7 0.0 2.4 2 1 0 2 2 2 0 PDGLE domain DUF3309 PF11752.8 OAJ23737.1 - 0.48 10.5 11.9 0.63 10.1 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DsbD_2 PF13386.6 OAJ23737.1 - 0.48 10.3 7.9 13 5.7 0.0 4.4 4 1 0 4 4 4 0 Cytochrome C biogenesis protein transmembrane region RNA_pol_Rpb8 PF03870.15 OAJ23738.1 - 5.8e-45 152.9 0.0 8e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OAJ23738.1 - 0.0099 15.9 0.0 4.2 7.5 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF1899 PF08953.11 OAJ23739.1 - 1.5e-30 104.8 0.7 3.5e-30 103.7 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OAJ23739.1 - 1.1e-18 66.8 0.9 5.4e-17 61.4 0.3 2.6 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 OAJ23739.1 - 5e-10 39.8 7.0 0.059 14.3 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ23739.1 - 0.0056 16.9 0.0 21 5.5 0.0 4.0 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ23739.1 - 0.013 14.5 0.0 0.97 8.3 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 OAJ23739.1 - 0.056 12.5 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain PRCC PF10253.9 OAJ23739.1 - 0.17 12.6 5.5 0.3 11.9 5.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting V_ATPase_I PF01496.19 OAJ23740.1 - 2.6 5.8 7.0 3.9 5.3 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 OAJ23740.1 - 3.2 7.3 17.6 0.097 12.3 11.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) LCD1 PF09798.9 OAJ23740.1 - 6.7 5.1 10.3 4.5 5.7 0.0 2.3 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF1115 PF06544.12 OAJ23741.1 - 0.0015 18.7 0.0 0.03 14.4 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) Not3 PF04065.15 OAJ23741.1 - 0.11 11.9 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component zinc_ribbon_10 PF10058.9 OAJ23743.1 - 3.6e-07 29.8 0.0 7.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein TFIIA PF03153.13 OAJ23743.1 - 5.5 6.9 17.4 7.7 6.4 17.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 OAJ23743.1 - 5.5 6.1 10.0 8 5.5 10.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein polyprenyl_synt PF00348.17 OAJ23744.1 - 1.4e-53 181.6 0.0 5.1e-27 94.6 0.0 2.3 2 1 0 2 2 2 2 Polyprenyl synthetase Rep_fac-A_C PF08646.10 OAJ23745.1 - 0.11 12.2 2.4 0.13 12.0 2.4 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain DUF1151 PF06625.11 OAJ23745.1 - 3.1 7.8 12.9 0.38 10.7 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) CPP1-like PF11833.8 OAJ23745.1 - 5.2 6.7 5.9 7.3 6.2 5.9 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CwfJ_C_1 PF04677.15 OAJ23747.1 - 1.6e-21 76.4 0.0 3.7e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 OAJ23747.1 - 1e-11 44.4 11.6 1.8e-08 34.0 4.0 2.4 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 OAJ23747.1 - 3e-07 31.2 1.5 4.2e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 OAJ23747.1 - 0.016 15.3 0.3 0.05 13.7 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle Oxidored_FMN PF00724.20 OAJ23749.1 - 7.6e-43 147.1 0.0 3.1e-35 122.0 0.0 3.1 3 0 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OAJ23749.1 - 0.014 14.9 0.0 4 6.8 0.0 2.3 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Dus PF01207.17 OAJ23749.1 - 0.17 10.9 0.1 0.45 9.6 0.1 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) SNARE_assoc PF09335.11 OAJ23750.1 - 6.3e-22 78.3 5.5 1.4e-13 51.3 0.0 3.3 4 0 0 4 4 4 2 SNARE associated Golgi protein Myb_DNA-binding PF00249.31 OAJ23751.1 - 1.2e-10 41.4 0.2 4.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ23751.1 - 0.023 14.6 1.3 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like UQ_con PF00179.26 OAJ23752.1 - 8.8e-54 181.0 0.0 9.8e-54 180.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ23752.1 - 0.0077 15.9 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ23752.1 - 0.063 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAJ23752.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Na_Ca_ex PF01699.24 OAJ23761.1 - 4.8e-26 91.5 15.3 4.8e-26 91.5 15.3 1.6 2 0 0 2 2 2 1 Sodium/calcium exchanger protein DUF2589 PF11655.8 OAJ23761.1 - 1.2 9.5 3.4 0.53 10.6 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) Phage_holin_3_5 PF16085.5 OAJ23761.1 - 3.5 7.8 6.1 4.5 7.5 2.2 2.4 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III AAA_lid_7 PF17867.1 OAJ23762.1 - 0.02 15.1 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 Midasin AAA lid domain PDE6_gamma PF04868.12 OAJ23762.1 - 0.31 11.3 5.8 5.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Ribosomal_60s PF00428.19 OAJ23762.1 - 7.3 7.3 16.5 9.1 6.9 8.7 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Npa1 PF11707.8 OAJ23763.1 - 3.3e-75 253.6 0.4 1.2e-45 156.4 0.0 3.7 4 1 0 4 4 4 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAJ23763.1 - 9.9e-47 159.1 0.6 2.9e-46 157.6 0.6 1.9 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Lactonase PF10282.9 OAJ23765.1 - 8.2e-68 229.2 0.0 1e-67 228.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SCAB-Ig PF16709.5 OAJ23765.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Cadherin_4 PF17803.1 OAJ23765.1 - 5.3 7.7 12.4 3.6 8.3 4.9 3.6 2 2 0 2 2 2 0 Bacterial cadherin-like domain Na_Ca_ex PF01699.24 OAJ23767.1 - 1.6e-20 73.6 17.2 3.2e-20 72.6 17.2 1.5 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4027 PF13219.6 OAJ23767.1 - 0.034 14.0 0.9 0.09 12.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) CDC45 PF02724.14 OAJ23767.1 - 3.4 5.9 10.5 0.76 8.0 1.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Spt5_N PF11942.8 OAJ23767.1 - 5.6 8.0 23.3 2 9.4 0.6 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal PPP4R2 PF09184.11 OAJ23767.1 - 9.5 5.7 13.9 0.38 10.3 4.4 2.1 2 0 0 2 2 2 0 PPP4R2 Ctr PF04145.15 OAJ23769.1 - 6.6 7.3 7.5 54 4.4 2.9 3.7 2 2 0 2 2 2 0 Ctr copper transporter family RRM_1 PF00076.22 OAJ23770.1 - 1.5e-12 47.1 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ23770.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ23770.1 - 0.079 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif SET PF00856.28 OAJ23771.1 - 7e-19 68.8 0.3 7e-19 68.8 0.3 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.11 OAJ23771.1 - 4.6e-17 62.0 7.6 4.6e-17 62.0 7.6 2.0 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 OAJ23771.1 - 7.3e-13 48.3 4.0 7.3e-13 48.3 4.0 2.2 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 OAJ23771.1 - 0.029 14.4 1.2 0.055 13.5 0.1 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain SOAR PF16533.5 OAJ23771.1 - 0.041 13.8 0.6 0.041 13.8 0.6 2.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region Macoilin PF09726.9 OAJ23771.1 - 1.9 6.9 13.1 3.7 6.0 13.1 1.4 1 0 0 1 1 1 0 Macoilin family GNAT_acetyltr_2 PF13718.6 OAJ23772.1 - 1.3e-74 250.4 0.0 3.2e-74 249.2 0.0 1.6 1 1 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OAJ23772.1 - 5.6e-53 180.1 0.2 9.1e-51 172.8 0.2 2.4 1 1 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OAJ23772.1 - 1.3e-50 171.7 0.0 2.2e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 OAJ23772.1 - 1.4e-27 95.4 0.0 3.3e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) TIP_N PF12457.8 OAJ23772.1 - 7.7 7.0 9.1 0.99 9.8 1.0 2.4 2 0 0 2 2 2 0 Tuftelin interacting protein N terminal NIF PF03031.18 OAJ23773.1 - 2.4e-07 30.6 0.0 0.0048 16.7 0.0 3.2 4 0 0 4 4 4 2 NLI interacting factor-like phosphatase Endonuclease_NS PF01223.23 OAJ23774.1 - 1.4e-53 182.0 0.0 8.5e-51 172.9 0.0 2.1 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease RabGAP-TBC PF00566.18 OAJ23775.1 - 5.7e-49 166.7 0.0 7.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 OAJ23775.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ23775.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Autophagy_act_C PF03987.15 OAJ23776.1 - 4.4e-16 59.2 1.1 7.9e-16 58.4 0.2 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain DUF515 PF04415.12 OAJ23776.1 - 5 5.4 10.3 7 4.9 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FancD2 PF14631.6 OAJ23777.1 - 8 3.7 8.0 19 2.5 8.0 1.5 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Asp PF00026.23 OAJ23782.1 - 2.5e-49 168.4 5.7 1.1e-48 166.3 5.7 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ23782.1 - 1.9e-06 28.2 3.6 0.055 13.7 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ23782.1 - 0.0031 17.3 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 OAJ23782.1 - 0.023 15.2 0.7 0.21 12.2 0.2 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ23782.1 - 0.031 14.9 1.6 0.56 10.9 0.9 2.6 2 0 0 2 2 2 0 Aspartyl protease DUF4497 PF14924.6 OAJ23782.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) OrsD PF12013.8 OAJ23783.1 - 8e-20 71.4 1.4 3.7e-11 43.5 0.2 4.3 4 0 0 4 4 4 2 Orsellinic acid/F9775 biosynthesis cluster protein D MPP6 PF10175.9 OAJ23783.1 - 5 7.6 18.5 1.2 9.6 0.1 3.6 3 0 0 3 3 3 0 M-phase phosphoprotein 6 zf_C2H2_ZHX PF18387.1 OAJ23783.1 - 8.2 6.2 13.5 31 4.3 0.0 3.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Rpr2 PF04032.16 OAJ23784.1 - 4e-12 46.2 0.1 4e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 OAJ23784.1 - 0.0051 16.8 0.9 0.0091 16.0 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon SMC_N PF02463.19 OAJ23785.1 - 7.3e-27 94.2 0.0 2.5e-26 92.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ23785.1 - 2.1e-14 54.5 10.2 2.1e-14 54.5 10.2 5.5 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 OAJ23785.1 - 8.8e-13 48.7 8.6 8.8e-13 48.7 8.6 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAJ23785.1 - 0.00021 21.2 9.0 0.053 13.3 0.4 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4527 PF15030.6 OAJ23785.1 - 0.00039 19.9 11.8 0.0049 16.3 0.7 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4527) AAA_29 PF13555.6 OAJ23785.1 - 0.0035 17.0 0.2 0.0085 15.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 OAJ23785.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.13 OAJ23785.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Fer4_NifH PF00142.18 OAJ23785.1 - 2.6 7.4 4.8 0.62 9.5 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APC_N_CC PF16689.5 OAJ23785.1 - 9.4 6.4 9.6 17 5.5 1.4 3.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain RNase_HII PF01351.18 OAJ23786.1 - 2.5e-43 148.2 0.0 6.4e-39 133.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII FXMRP1_C_core PF12235.8 OAJ23786.1 - 0.048 14.3 5.3 0.15 12.7 5.3 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal CD52 PF15116.6 OAJ23786.1 - 6 7.0 8.1 12 6.0 1.2 3.0 2 0 0 2 2 2 0 CAMPATH-1 antigen Mannosyl_trans PF05007.13 OAJ23790.1 - 1.4e-52 179.1 19.0 4.5e-48 164.4 16.0 3.5 2 1 0 2 2 2 2 Mannosyltransferase (PIG-M) Piwi PF02171.17 OAJ23791.1 - 7.8e-74 248.6 0.0 1.1e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAJ23791.1 - 6.9e-14 52.6 0.0 2.6e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAJ23791.1 - 3.4e-11 42.6 0.4 9.2e-11 41.3 0.4 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 OAJ23791.1 - 8.1e-10 38.6 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 OAJ23791.1 - 1e-09 38.5 1.0 2.1e-09 37.6 0.2 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAJ23791.1 - 2e-08 34.4 0.0 4.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute DUF1797 PF08796.10 OAJ23791.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) DNA_pol_A_exo1 PF01612.20 OAJ23792.1 - 7.3e-38 130.0 0.2 1.1e-37 129.5 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAJ23792.1 - 3.5e-20 72.5 0.1 4.6e-19 68.9 0.0 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAJ23792.1 - 1.1e-11 44.5 0.2 2.2e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 HRDC domain WD40 PF00400.32 OAJ23793.1 - 5.6e-20 71.3 13.7 0.0014 19.4 0.1 6.7 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ23793.1 - 1.3e-07 31.9 0.1 0.28 11.5 0.0 4.6 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 OAJ23793.1 - 0.0011 18.9 0.1 0.0017 18.3 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SGL PF08450.12 OAJ23793.1 - 0.0031 17.1 0.0 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 OAJ23793.1 - 0.81 9.7 4.3 69 3.6 0.1 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat HLH PF00010.26 OAJ23794.1 - 0.00013 21.8 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1_dh PF00676.20 OAJ23796.1 - 3.4e-56 190.4 0.9 4.5e-56 190.0 0.9 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAJ23796.1 - 0.00034 19.9 0.0 0.00069 18.9 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OAJ23796.1 - 0.013 15.3 1.1 0.03 14.1 0.8 1.7 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain V-ATPase_H_N PF03224.14 OAJ23797.1 - 8.8e-81 271.6 0.0 2.9e-80 269.9 0.0 1.8 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAJ23797.1 - 6.8e-31 106.8 0.0 3.3e-30 104.6 0.0 2.3 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 OAJ23797.1 - 0.0097 16.1 0.0 0.9 10.0 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat ORC6 PF05460.13 OAJ23797.1 - 0.17 11.1 2.5 0.35 10.1 2.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ORC2 PF04084.14 OAJ23802.1 - 1.6e-37 129.2 0.0 7.6e-32 110.5 0.0 2.8 2 1 0 2 2 2 2 Origin recognition complex subunit 2 PBP1_TM PF14812.6 OAJ23802.1 - 0.49 10.8 15.8 4.8 7.6 0.1 5.4 5 0 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPP_enzyme_N PF02776.18 OAJ23803.1 - 1.2e-52 178.0 2.3 4.7e-52 176.0 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAJ23803.1 - 1.3e-47 161.4 0.1 4.2e-46 156.5 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAJ23803.1 - 8.8e-41 138.9 0.7 1.8e-40 137.8 0.3 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RhoGAP PF00620.27 OAJ23804.1 - 2.3e-06 27.5 0.0 0.00011 22.1 0.0 3.2 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.23 OAJ23804.1 - 0.046 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain NIF PF03031.18 OAJ23805.1 - 4.4e-53 179.2 0.1 6.2e-53 178.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 OAJ23805.1 - 0.097 13.1 0.1 0.58 10.5 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CENP-B_dimeris PF09026.10 OAJ23805.1 - 0.51 10.8 9.8 1.2 9.6 9.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAJ23805.1 - 5.4 5.0 15.6 8.2 4.4 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ23805.1 - 5.5 6.2 10.9 13 5.0 10.9 1.5 1 0 0 1 1 1 0 NOA36 protein Aldose_epim PF01263.20 OAJ23806.1 - 2.9e-57 194.3 0.1 4.8e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase SQS_PSY PF00494.19 OAJ23807.1 - 1.3e-47 162.5 1.1 1.7e-47 162.1 1.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase BCIP PF13862.6 OAJ23808.1 - 1.5e-34 119.6 0.1 6.1e-34 117.6 0.1 1.9 1 1 0 1 1 1 1 p21-C-terminal region-binding protein FRQ PF09421.10 OAJ23808.1 - 4e-05 21.9 3.1 0.017 13.2 0.0 2.1 2 0 0 2 2 2 2 Frequency clock protein D123 PF07065.14 OAJ23808.1 - 0.016 14.4 0.1 0.016 14.4 0.1 1.8 2 0 0 2 2 2 0 D123 YL1 PF05764.13 OAJ23808.1 - 0.02 15.0 0.2 0.02 15.0 0.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.6 OAJ23808.1 - 0.47 10.8 12.9 2 8.8 2.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 OAJ23808.1 - 0.73 9.8 9.2 5.4 7.0 2.0 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 TLP-20 PF06088.11 OAJ23808.1 - 0.76 9.6 3.7 6.1 6.7 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 OAJ23808.1 - 1.1 8.9 5.0 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 FAM176 family SURF2 PF05477.11 OAJ23808.1 - 1.1 8.9 5.6 1.4 8.5 1.2 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF3246 PF11596.8 OAJ23808.1 - 1.2 8.6 9.0 0.55 9.6 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 OAJ23808.1 - 1.6 8.4 11.0 0.56 9.9 2.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 OAJ23808.1 - 7.1 6.2 7.0 10 5.6 0.8 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 OAJ23808.1 - 7.1 5.9 9.6 2.4 7.4 2.0 2.1 2 0 0 2 2 2 0 NOA36 protein MFS_1 PF07690.16 OAJ23809.1 - 4.2e-46 157.5 38.2 3e-45 154.7 16.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ23809.1 - 1.2e-08 34.2 8.0 1.2e-08 34.2 8.0 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAJ23809.1 - 1.8e-06 26.6 0.6 4.3e-06 25.3 0.6 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 OAJ23809.1 - 1.4e-05 23.7 4.4 2.8e-05 22.7 4.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAJ23809.1 - 0.0089 14.5 4.4 0.017 13.6 4.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF21 PF01595.20 OAJ23809.1 - 0.048 13.4 0.2 0.048 13.4 0.2 3.1 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain JmjC PF02373.22 OAJ23810.1 - 5.4e-41 139.6 0.1 1.2e-40 138.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ23810.1 - 1.2e-10 41.2 0.1 2.9e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 OAJ23810.1 - 8.9e-10 38.7 1.8 8.9e-10 38.7 1.8 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAJ23810.1 - 6.8e-09 35.9 4.5 1.7e-08 34.6 1.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 OAJ23810.1 - 2.8 7.9 6.3 7.3 6.6 6.3 1.7 1 0 0 1 1 1 0 PHD-finger Spt20 PF12090.8 OAJ23810.1 - 4.5 6.8 23.3 12 5.4 23.3 1.7 1 0 0 1 1 1 0 Spt20 family zf-C3HC4_3 PF13920.6 OAJ23811.1 - 1.5e-06 27.9 7.9 1.5e-06 27.9 7.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF971 PF06155.12 OAJ23811.1 - 0.49 11.1 0.0 0.49 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF971) zf-C2H2 PF00096.26 OAJ23811.1 - 2.6 8.7 24.2 0.13 12.7 0.5 5.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type Abhydrolase_1 PF00561.20 OAJ23812.1 - 1.6e-21 77.1 0.0 1.1e-20 74.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ23812.1 - 1.9e-16 61.3 0.9 2.4e-15 57.8 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ23812.1 - 9.8e-14 51.2 0.0 2.8e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAJ23812.1 - 2.5e-06 27.4 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 OAJ23812.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 OAJ23812.1 - 0.0014 18.6 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAJ23812.1 - 0.0016 18.4 0.2 0.0086 16.0 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OAJ23812.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 OAJ23812.1 - 0.035 12.8 0.0 0.06 12.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF2207 PF09972.9 OAJ23813.1 - 0.13 11.0 0.6 6.2 5.5 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) PI3K_1B_p101 PF10486.9 OAJ23814.1 - 0.029 12.2 3.1 0.07 10.9 3.1 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.6 OAJ23814.1 - 1.1 9.7 11.5 0.78 10.2 5.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.16 OAJ23815.1 - 1e-32 113.5 11.7 1.5e-32 113.0 11.7 1.2 1 0 0 1 1 1 1 TLC domain zf-HIT PF04438.16 OAJ23816.1 - 7.7e-08 32.1 9.6 1.3e-07 31.4 9.6 1.3 1 0 0 1 1 1 1 HIT zinc finger NUDIX PF00293.28 OAJ23821.1 - 5.6e-08 32.9 0.1 1.3e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain GATase_4 PF13230.6 OAJ23821.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF1768 PF08719.11 OAJ23822.1 - 0.19 12.0 0.0 0.25 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) DUF1768 PF08719.11 OAJ23823.1 - 5.6e-24 85.2 0.0 1.2e-23 84.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 OAJ23824.1 - 4.8e-23 82.2 0.5 1.4e-22 80.6 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 OAJ23826.1 - 5.7e-15 55.9 1.8 8.8e-13 48.8 1.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) GCS PF03074.16 OAJ23827.1 - 6e-159 529.3 0.0 7.3e-133 443.4 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase DUF3246 PF11596.8 OAJ23827.1 - 0.47 9.8 2.7 0.91 8.9 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 OAJ23827.1 - 1.6 9.2 6.5 0.48 10.8 2.7 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OAJ23827.1 - 3.1 7.5 6.0 6.6 6.4 6.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RIO1 PF01163.22 OAJ23828.1 - 2.3e-38 131.7 0.1 2.4e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 OAJ23828.1 - 3.9e-29 100.7 0.0 9e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OAJ23828.1 - 2.6e-07 30.8 0.8 0.00036 20.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAJ23828.1 - 0.0031 16.9 0.0 0.027 13.8 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.19 OAJ23828.1 - 0.76 10.4 0.0 0.76 10.4 0.0 4.5 3 1 0 3 3 3 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 OAJ23828.1 - 4.8 7.4 41.1 0.075 13.3 15.6 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 SpoIIIAH PF12685.7 OAJ23828.1 - 8.4 6.2 25.1 0.31 10.9 8.2 2.4 3 0 0 3 3 3 0 SpoIIIAH-like protein Muted PF14942.6 OAJ23829.1 - 0.0057 17.0 3.1 5 7.4 0.1 3.6 1 1 3 4 4 4 2 Organelle biogenesis, Muted-like protein DUF35_N PF12172.8 OAJ23829.1 - 0.0073 16.2 1.6 33 4.5 0.0 4.7 5 0 0 5 5 5 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DrsE_2 PF13686.6 OAJ23829.1 - 0.09 12.7 1.3 21 5.0 0.0 4.1 6 0 0 6 6 6 0 DsrE/DsrF/DrsH-like family DUF4423 PF14394.6 OAJ23829.1 - 0.12 12.1 1.0 76 3.0 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4423) Phage_CI_C PF16452.5 OAJ23829.1 - 0.27 11.5 14.1 5.7 7.3 0.2 5.6 5 2 1 7 7 7 0 Bacteriophage CI repressor C-terminal domain DUF2540 PF10802.8 OAJ23829.1 - 0.29 11.2 2.4 6.1 7.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2540) DUF4588 PF15251.6 OAJ23829.1 - 0.63 9.8 6.4 2.6 7.7 0.3 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4588) Endonuc-PvuII PF09225.10 OAJ23829.1 - 0.77 9.5 11.1 1.6 8.5 0.1 4.5 3 2 2 6 6 6 0 Restriction endonuclease PvuII Late_protein_L2 PF00513.18 OAJ23829.1 - 2.7 6.9 7.3 2.1 7.3 0.3 3.0 1 1 1 3 3 3 0 Late Protein L2 Lon_C PF05362.13 OAJ23830.1 - 2.7e-66 223.0 0.2 5.6e-66 222.0 0.2 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAJ23830.1 - 1.9e-31 109.5 0.0 4.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAJ23830.1 - 1.9e-21 76.8 0.0 7.2e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 OAJ23830.1 - 1.5e-06 28.0 0.0 3.9e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 OAJ23830.1 - 4.6e-06 26.9 0.0 8.5e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAJ23830.1 - 6.5e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 OAJ23830.1 - 7.4e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 OAJ23830.1 - 0.0011 18.7 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ23830.1 - 0.0012 19.2 0.0 0.0045 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ23830.1 - 0.0017 18.6 0.4 0.069 13.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ23830.1 - 0.0041 17.7 0.9 0.01 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ23830.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ23830.1 - 0.041 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OAJ23830.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 OAJ23830.1 - 0.086 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 OAJ23830.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ23830.1 - 0.099 11.8 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.12 OAJ23830.1 - 0.12 12.2 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 OAJ23830.1 - 0.15 12.6 1.5 0.37 11.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 OAJ23830.1 - 0.23 11.3 2.9 17 5.2 0.0 3.3 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea RT_RNaseH PF17917.1 OAJ23831.1 - 8.4e-13 48.5 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ23831.1 - 2.1e-07 30.9 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Y_phosphatase2 PF03162.13 OAJ23832.1 - 2.8e-22 79.0 0.0 3.8e-13 49.4 0.0 2.5 3 0 0 3 3 3 2 Tyrosine phosphatase family Ribosomal_60s PF00428.19 OAJ23832.1 - 0.012 16.2 9.5 0.028 15.0 9.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RXT2_N PF08595.11 OAJ23832.1 - 0.17 11.9 6.4 0.29 11.2 4.3 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Myc_N PF01056.18 OAJ23832.1 - 0.48 10.3 5.3 0.083 12.8 0.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region BSP_II PF05432.11 OAJ23832.1 - 0.64 9.7 15.0 25 4.4 13.7 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4746 PF15928.5 OAJ23832.1 - 1.5 8.2 7.7 2.1 7.7 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 OAJ23832.1 - 1.7 8.5 5.8 1.8 8.5 1.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 OAJ23832.1 - 5.9 6.2 5.8 4.6 6.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Sporozoite_P67 PF05642.11 OAJ23832.1 - 7.8 4.4 7.8 0.59 8.1 1.5 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2722 PF10846.8 OAJ23832.1 - 8.9 5.1 9.4 12 4.7 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) muHD PF10291.9 OAJ23833.1 - 7.7e-37 127.2 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OAJ23833.1 - 6.1e-06 26.4 0.5 3.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.21 OAJ23833.1 - 7.9e-06 25.4 0.0 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Atg14 PF10186.9 OAJ23833.1 - 0.1 11.7 1.3 0.2 10.7 1.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAJ23833.1 - 0.11 11.4 1.7 0.17 10.8 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 OAJ23833.1 - 0.11 12.7 1.2 0.44 10.8 1.2 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain BCDHK_Adom3 PF10436.9 OAJ23833.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PKcGMP_CC PF16808.5 OAJ23833.1 - 0.3 11.0 1.8 0.27 11.1 0.3 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HrpB7 PF09486.10 OAJ23833.1 - 1 9.8 12.5 0.027 14.9 5.2 2.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) APG6_N PF17675.1 OAJ23833.1 - 3.3 8.2 5.7 3.4 8.2 4.0 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DDE_3 PF13358.6 OAJ23834.1 - 1.6e-27 96.1 0.0 2.8e-27 95.3 0.0 1.4 1 1 1 2 2 2 1 DDE superfamily endonuclease rve PF00665.26 OAJ23834.1 - 0.11 12.7 0.0 0.41 10.8 0.0 1.7 1 1 1 2 2 2 0 Integrase core domain Ank_4 PF13637.6 OAJ23835.1 - 2e-20 72.8 0.7 4.5e-12 46.2 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ23835.1 - 6.1e-17 62.0 0.1 6.8e-09 36.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ23835.1 - 2.8e-14 52.8 0.0 0.00017 21.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAJ23835.1 - 9.9e-14 51.2 0.4 1.1e-06 28.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ23835.1 - 5.2e-11 41.8 0.1 0.005 17.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 OAJ23835.1 - 1.6e-05 24.7 1.7 9.9e-05 22.2 0.2 2.5 2 1 0 2 2 2 1 KilA-N domain SOAR PF16533.5 OAJ23835.1 - 0.17 11.8 0.6 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF4407 PF14362.6 OAJ23835.1 - 0.66 9.3 9.7 0.58 9.5 6.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Epimerase PF01370.21 OAJ23836.1 - 3.2e-15 56.3 0.0 6.8e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ23836.1 - 6.5e-14 51.6 0.0 3.3e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ23836.1 - 3.1e-09 36.4 0.0 1.4e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAJ23836.1 - 4.2e-07 30.0 0.0 6.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAJ23836.1 - 5.3e-05 22.8 0.0 0.00015 21.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1490 PF07371.12 OAJ23836.1 - 0.094 12.8 0.3 9.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) RmlD_sub_bind PF04321.17 OAJ23836.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain zf-C3HC4_3 PF13920.6 OAJ23838.1 - 1.4e-08 34.4 7.6 4.6e-08 32.8 7.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ23838.1 - 1.9e-05 24.4 4.2 3.4e-05 23.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ23838.1 - 0.00062 20.0 6.4 0.0015 18.8 6.4 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAJ23838.1 - 0.0012 18.8 3.8 0.0021 18.0 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ23838.1 - 0.0016 18.2 5.3 0.016 15.1 5.3 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAJ23838.1 - 0.0037 17.2 2.8 0.019 15.0 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ23838.1 - 0.091 12.6 5.7 0.054 13.3 2.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAJ23838.1 - 1.1 9.1 3.8 3.3 7.6 3.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sec62 PF03839.16 OAJ23838.1 - 2.5 7.6 3.7 34 3.9 0.0 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 CRAL_TRIO PF00650.20 OAJ23839.1 - 9.5e-27 93.7 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ23839.1 - 1.8e-10 40.9 0.5 6e-10 39.2 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ23839.1 - 2.3e-06 27.8 0.0 3.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Brr6_like_C_C PF10104.9 OAJ23840.1 - 1e-36 125.7 0.3 1.4e-36 125.2 0.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain p450 PF00067.22 OAJ23841.1 - 7.8e-60 202.9 0.6 1.5e-49 169.0 0.6 3.8 1 1 1 2 2 2 2 Cytochrome P450 TM_helix PF05552.12 OAJ23841.1 - 6.2 6.9 7.2 14 5.7 7.2 1.6 1 0 0 1 1 1 0 Conserved TM helix Pet127 PF08634.10 OAJ23845.1 - 5.5e-103 344.2 0.2 7.4e-103 343.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DHHC PF01529.20 OAJ23846.1 - 2.9e-31 108.3 13.0 5.9e-31 107.4 13.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OAJ23846.1 - 3.1e-24 85.4 0.2 1.5e-14 54.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ23846.1 - 1.1e-19 70.5 5.6 5e-08 33.3 0.2 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ23846.1 - 1.4e-18 65.0 3.0 0.00032 20.9 0.1 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OAJ23846.1 - 5.8e-17 61.5 3.2 0.0014 18.9 0.0 5.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAJ23846.1 - 4.3e-13 49.1 11.4 0.0004 20.7 0.2 6.2 7 0 0 7 7 7 3 Ankyrin repeat vMSA PF00695.19 OAJ23846.1 - 0.31 10.1 8.1 0.57 9.2 8.1 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DEAD PF00270.29 OAJ23849.1 - 3.2e-18 66.1 0.1 8.8e-18 64.7 0.0 1.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ23849.1 - 0.021 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Epimerase PF01370.21 OAJ23851.1 - 0.0002 20.9 0.0 0.00054 19.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ23851.1 - 0.0059 16.5 0.5 0.017 15.0 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAJ23851.1 - 0.046 12.8 0.0 0.24 10.5 0.0 2.1 2 1 1 3 3 3 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAJ23851.1 - 0.095 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RVT_2 PF07727.14 OAJ23852.1 - 1.5e-71 240.9 0.0 2.1e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ23852.1 - 3.9e-16 59.3 0.2 2.8e-15 56.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ23852.1 - 1.2e-05 25.0 0.4 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ23852.1 - 0.00027 20.6 0.0 0.00085 19.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ23852.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Tcp11 PF05794.13 OAJ23853.1 - 1.5e-08 34.2 0.1 3.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 T-complex protein 11 Phage_r1t_holin PF16945.5 OAJ23853.1 - 0.047 13.9 0.6 0.047 13.9 0.6 2.2 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin ABC_membrane PF00664.23 OAJ23854.1 - 5.3e-45 154.2 33.0 2e-27 96.5 12.8 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ23854.1 - 3.8e-41 140.8 0.0 3.3e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ23854.1 - 3.1e-08 33.3 3.3 0.013 14.9 0.1 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ23854.1 - 0.00018 22.1 0.0 0.8 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAJ23854.1 - 0.00035 20.2 0.3 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ23854.1 - 0.0016 18.7 0.6 2 8.7 0.1 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAJ23854.1 - 0.011 15.9 0.2 0.011 15.9 0.2 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_7 PF12775.7 OAJ23854.1 - 0.015 14.8 0.4 0.66 9.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ23854.1 - 0.017 15.5 0.1 0.21 12.0 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OAJ23854.1 - 0.025 14.5 0.3 0.66 9.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 OAJ23854.1 - 0.051 14.0 0.3 4.9 7.6 0.2 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAJ23854.1 - 0.084 12.6 0.4 13 5.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OAJ23854.1 - 0.099 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ23854.1 - 0.11 12.4 0.2 16 5.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 OAJ23854.1 - 0.13 11.6 0.4 12 5.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF5506 PF17611.2 OAJ23854.1 - 0.18 11.7 2.9 0.2 11.6 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5506) AAA_18 PF13238.6 OAJ23854.1 - 0.2 12.2 0.2 3.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ23854.1 - 0.2 12.0 1.0 3.5 8.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.6 OAJ23854.1 - 0.4 10.8 3.3 19 5.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain zf-CCHC PF00098.23 OAJ23855.1 - 0.13 12.4 1.7 0.26 11.4 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ23855.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 OAJ23856.1 - 8.9e-73 244.9 0.0 1.3e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ23856.1 - 1.3e-14 54.4 0.0 1.5e-13 51.0 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ23856.1 - 1.7e-05 24.6 0.0 7.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain UBM PF14377.6 OAJ23857.1 - 0.078 12.5 0.2 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin binding region RVT_2 PF07727.14 OAJ23858.1 - 8.1e-29 101.0 0.0 1e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Voldacs PF03517.13 OAJ23858.1 - 7e-18 65.1 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DHHC PF01529.20 OAJ23859.1 - 1.5e-34 118.9 5.4 1.5e-34 118.9 5.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 OAJ23859.1 - 0.45 10.7 3.1 1.1 9.4 3.1 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Skp1_POZ PF03931.15 OAJ23860.1 - 0.00073 19.7 0.0 0.0047 17.1 0.0 2.0 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain RVT_1 PF00078.27 OAJ23861.1 - 9.4e-25 87.4 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ23861.1 - 4.5e-22 78.0 0.0 1.1e-13 51.0 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ23861.1 - 1.2e-15 57.3 0.0 2.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ23861.1 - 2.1e-15 56.9 0.0 2.2e-10 40.7 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ23861.1 - 1.7e-11 44.4 0.0 6.4e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ23861.1 - 5.8e-05 23.7 0.0 0.00017 22.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ23861.1 - 0.0036 17.8 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Sod_Fe_C PF02777.18 OAJ23862.1 - 5.6e-35 119.6 0.2 1.2e-34 118.5 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ23862.1 - 2.5e-32 111.2 3.1 4.7e-32 110.3 3.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RRM_1 PF00076.22 OAJ23863.1 - 3e-58 193.6 0.0 1.3e-19 69.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ23863.1 - 7.5e-11 41.7 0.0 5e-05 22.9 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ23863.1 - 1e-06 28.5 0.0 0.00019 21.2 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAJ23863.1 - 4.4e-05 23.5 0.0 0.11 12.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ23863.1 - 0.00026 20.9 0.0 1.5 8.9 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 OAJ23863.1 - 0.00074 19.8 0.0 0.06 13.6 0.0 2.7 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 OAJ23863.1 - 0.013 15.2 0.0 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Cas_Cas2CT1978 PF09707.10 OAJ23863.1 - 0.043 13.9 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF4523 PF15023.6 OAJ23863.1 - 0.28 11.0 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) GST_N_3 PF13417.6 OAJ23869.1 - 0.00035 20.9 0.0 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF1365 PF07103.11 OAJ23870.1 - 2.4e-53 181.3 0.0 3.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) HLH PF00010.26 OAJ23871.1 - 3.1e-16 59.1 0.1 6.7e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.19 OAJ23871.1 - 0.0027 18.2 3.5 0.0027 18.2 3.5 6.5 6 0 0 6 6 6 1 60s Acidic ribosomal protein IML1 PF12257.8 OAJ23872.1 - 2e-112 375.0 0.0 2.7e-112 374.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OAJ23872.1 - 7.5e-16 58.0 0.1 2.3e-15 56.4 0.1 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) rve_3 PF13683.6 OAJ23872.1 - 0.12 12.2 1.9 0.35 10.7 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain ACBP PF00887.19 OAJ23873.1 - 9.6e-31 105.8 0.2 1.3e-30 105.4 0.2 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Exonuc_X-T_C PF08411.10 OAJ23873.1 - 0.1 11.7 0.4 0.14 11.3 0.4 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal COX6B PF02297.17 OAJ23874.1 - 3.7e-19 68.7 8.6 4.5e-19 68.5 8.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RSN1_7TM PF02714.15 OAJ23875.1 - 1.7e-74 250.6 21.2 2.8e-74 249.9 21.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ23875.1 - 1e-39 136.5 0.2 1.6e-39 136.0 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ23875.1 - 1.6e-34 118.9 2.2 1.6e-34 118.9 2.2 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAJ23875.1 - 1.5e-09 37.9 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Dicistro_VP4 PF11492.8 OAJ23875.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 Hydrolase_4 PF12146.8 OAJ23876.1 - 0.0002 20.7 0.1 0.011 15.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Methyltransf_28 PF02636.17 OAJ23876.1 - 0.063 12.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lipase_3 PF01764.25 OAJ23876.1 - 0.089 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Phage_integrase PF00589.22 OAJ23877.1 - 3e-05 23.9 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF3504 PF12012.8 OAJ23877.1 - 0.096 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) RVT_2 PF07727.14 OAJ23878.1 - 2.4e-70 237.0 0.0 3.4e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ23878.1 - 1.6e-20 73.5 0.0 4.8e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ23878.1 - 0.0001 22.0 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 OAJ23878.1 - 0.00012 21.7 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ23878.1 - 0.002 17.9 0.1 0.007 16.2 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3128 PF11326.8 OAJ23878.1 - 0.055 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Transcript_VP30 PF11507.8 OAJ23878.1 - 0.11 12.6 0.5 0.25 11.4 0.2 1.7 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 Porin_3 PF01459.22 OAJ23879.1 - 1.1e-69 234.9 1.0 1.3e-69 234.7 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rrp15p PF07890.12 OAJ23880.1 - 1.3e-29 103.2 1.2 2.3e-28 99.2 0.0 2.9 2 1 0 2 2 2 1 Rrp15p YL1 PF05764.13 OAJ23880.1 - 2.1e-06 28.0 13.6 4.6e-06 26.9 13.6 1.5 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAJ23880.1 - 0.0053 15.1 8.9 0.0078 14.6 8.9 1.2 1 0 0 1 1 1 1 CDC45-like protein TFB6 PF17110.5 OAJ23880.1 - 0.03 14.1 4.0 0.073 12.8 3.1 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TFIIF_alpha PF05793.12 OAJ23880.1 - 0.032 12.8 20.6 0.057 12.0 20.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF5632 PF18646.1 OAJ23880.1 - 0.045 13.8 0.2 0.1 12.7 0.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5632) Nop14 PF04147.12 OAJ23880.1 - 0.25 9.5 18.7 0.045 12.0 15.3 1.5 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ23880.1 - 1.1 7.3 33.0 1.9 6.5 33.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 OAJ23880.1 - 1.4 8.2 29.2 0.086 12.2 21.8 2.0 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 OAJ23880.1 - 8.9 5.6 25.4 17 4.7 25.4 1.5 1 1 0 1 1 1 0 SDA1 PMT_4TMC PF16192.5 OAJ23882.1 - 2.7e-52 177.3 5.7 1.1e-51 175.3 5.7 2.1 1 1 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 OAJ23882.1 - 2.6e-39 135.3 18.6 4.2e-39 134.6 18.6 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 OAJ23882.1 - 2.9e-26 92.5 0.1 5e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 MIR domain Pro-kuma_activ PF09286.11 OAJ23883.1 - 1.4e-16 61.1 0.0 2.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAJ23883.1 - 7.5e-11 41.8 5.1 1.6e-10 40.8 5.1 1.5 1 0 0 1 1 1 1 Subtilase family YlaH PF14036.6 OAJ23884.1 - 0.067 13.5 0.8 0.067 13.5 0.8 2.3 3 0 0 3 3 3 0 YlaH-like protein LIP PF03583.14 OAJ23893.1 - 2.2e-43 148.7 0.4 8.3e-42 143.5 0.4 2.1 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ23893.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SPRY PF00622.28 OAJ23894.1 - 7.7e-05 22.8 0.0 0.04 14.0 0.0 3.0 3 0 0 3 3 3 2 SPRY domain SUIM_assoc PF16619.5 OAJ23894.1 - 0.25 11.4 5.5 0.31 11.1 2.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CUE PF02845.16 OAJ23896.1 - 2.6e-12 46.2 0.1 4.4e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 CUE domain UNC-93 PF05978.16 OAJ23897.1 - 1.3e-05 24.9 5.6 1.3e-05 24.9 5.6 2.7 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAJ23897.1 - 2.1e-05 23.6 26.9 4.1e-05 22.7 26.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily ComJ PF11033.8 OAJ23897.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Competence protein J (ComJ) eIF3g PF12353.8 OAJ23898.1 - 1.5e-41 141.7 0.5 2.9e-41 140.8 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAJ23898.1 - 2.6e-18 65.6 0.0 4.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Svf1_C PF17187.4 OAJ23899.1 - 5.8e-46 156.3 0.0 1.2e-45 155.3 0.0 1.6 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 OAJ23899.1 - 7.5e-40 136.7 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain GCP_C_terminal PF04130.13 OAJ23900.1 - 5.2e-22 78.7 1.4 4.2e-13 49.5 0.0 3.3 3 1 0 3 3 3 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAJ23900.1 - 2.4e-16 60.3 0.1 1.3e-15 57.8 0.1 2.2 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal REC114-like PF15165.6 OAJ23900.1 - 3.4 7.4 8.5 6.6 6.4 8.5 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Activator_LAG-3 PF11498.8 OAJ23900.1 - 7.1 5.5 23.2 12 4.8 23.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA_gamma_N PF02268.16 OAJ23901.1 - 1.9e-24 85.4 0.1 2.4e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 OAJ23901.1 - 1.1e-19 70.3 0.2 1.6e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit NCBP3 PF10309.9 OAJ23902.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 OAJ23902.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain CDK2AP PF09806.9 OAJ23902.1 - 6.8 6.7 6.8 7.2 6.6 5.6 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein La PF05383.17 OAJ23903.1 - 6.4e-15 55.0 0.2 2.5e-14 53.1 0.2 2.0 1 1 0 1 1 1 1 La domain RRM_1 PF00076.22 OAJ23903.1 - 1.7e-05 24.5 0.1 4.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ23903.1 - 0.11 12.5 0.1 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif Cyt-b5 PF00173.28 OAJ23904.1 - 3.3e-23 81.6 0.3 3.6e-23 81.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 OAJ23904.1 - 0.11 12.7 0.0 0.37 10.9 0.0 1.8 1 1 1 2 2 2 0 V-ATPase subunit H HlyIII PF03006.20 OAJ23905.1 - 1.1e-49 169.1 20.0 1.4e-49 168.8 20.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_5 PF13346.6 OAJ23905.1 - 5 6.6 7.8 14 5.2 5.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Arrestin_C PF02752.22 OAJ23906.1 - 0.00027 21.4 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ23906.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SOUL PF04832.12 OAJ23906.1 - 0.086 13.0 0.2 0.3 11.3 0.2 1.9 1 0 0 1 1 1 0 SOUL heme-binding protein MFS_1 PF07690.16 OAJ23909.1 - 7.2e-36 123.8 12.1 1.1e-35 123.2 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Tad_C PF09977.9 OAJ23909.1 - 1.5 10.1 6.5 4.6 8.5 4.7 2.4 2 0 0 2 2 2 0 Putative Tad-like Flp pilus-assembly CTD_bind PF04818.13 OAJ23910.1 - 5.2e-05 24.0 0.0 0.00049 20.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase II-binding domain. DUF4054 PF13262.6 OAJ23910.1 - 2.8 8.0 5.2 0.6 10.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Pkinase PF00069.25 OAJ23914.1 - 4e-62 210.0 0.0 5.5e-60 203.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23914.1 - 1.5e-22 80.2 0.0 1.2e-20 73.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ23914.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IMUP PF15761.5 OAJ23914.1 - 0.0072 17.0 2.6 0.011 16.4 2.6 1.2 1 0 0 1 1 1 1 Immortalisation up-regulated protein APH PF01636.23 OAJ23914.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ23914.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAM199X PF15814.5 OAJ23914.1 - 0.032 13.3 0.7 0.045 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X FTA2 PF13095.6 OAJ23914.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1679 PF07914.11 OAJ23914.1 - 0.082 11.8 0.5 0.18 10.6 0.4 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 OAJ23914.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3138 PF11336.8 OAJ23914.1 - 0.35 9.4 2.6 0.48 9.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) D123 PF07065.14 OAJ23915.1 - 2.5e-77 260.0 0.0 5.4e-77 259.0 0.0 1.6 1 1 0 1 1 1 1 D123 Ofd1_CTDD PF10637.9 OAJ23916.1 - 1.1e-81 274.0 0.3 7e-77 258.2 0.4 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAJ23916.1 - 6.2e-33 113.3 0.0 1.4e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAJ23916.1 - 1.9e-15 57.5 0.0 4.8e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cwf_Cwc_15 PF04889.12 OAJ23916.1 - 0.62 9.8 10.1 1.5 8.5 10.1 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAJ23916.1 - 2.3 6.3 12.1 4.1 5.5 12.1 1.3 1 0 0 1 1 1 0 Nop14-like family ThrE PF06738.12 OAJ23917.1 - 2.2e-55 187.6 4.7 2.2e-55 187.6 4.7 2.5 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ23917.1 - 8.6e-08 32.4 7.7 8.6e-08 32.4 7.7 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE FA_desaturase PF00487.24 OAJ23917.1 - 0.14 11.9 5.2 0.15 11.8 3.1 2.2 2 0 0 2 2 2 0 Fatty acid desaturase F-box PF00646.33 OAJ23918.1 - 2e-07 30.7 1.6 3.5e-07 30.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ23918.1 - 0.00063 19.6 0.3 0.0024 17.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 OAJ23918.1 - 0.0082 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 F-box Fusion_gly PF00523.18 OAJ23918.1 - 0.17 10.1 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 LYTB PF02401.18 OAJ23918.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 LytB protein UDPGT PF00201.18 OAJ23919.1 - 2.5e-12 46.3 0.0 3.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF4913 PF16259.5 OAJ23920.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) Helicase_C PF00271.31 OAJ23921.1 - 1.4e-22 80.1 0.1 6.6e-22 78.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ23921.1 - 7.8e-21 74.8 0.0 2e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ23921.1 - 2.1e-15 56.9 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAJ23921.1 - 0.00091 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase WD40 PF00400.32 OAJ23922.1 - 4.5e-08 33.6 14.2 0.00058 20.6 0.2 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ23922.1 - 0.069 13.5 0.0 7.6 6.9 0.0 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 OAJ23922.1 - 0.081 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split Equine_IAV_S2 PF06502.11 OAJ23922.1 - 0.081 13.0 0.2 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein SCP2 PF02036.17 OAJ23923.1 - 1.3e-15 57.7 0.1 2.2e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family zf-AN1 PF01428.16 OAJ23924.1 - 1.2e-15 57.4 20.5 4.7e-11 42.7 5.4 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 OAJ23924.1 - 0.00031 21.0 13.1 0.039 14.3 2.8 3.2 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 OAJ23924.1 - 0.004 17.3 9.7 0.027 14.7 0.3 2.7 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain C1_4 PF07975.12 OAJ23924.1 - 0.16 12.3 8.6 0.97 9.7 0.3 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zf-CRD PF17979.1 OAJ23924.1 - 3.2 7.8 8.6 2.2 8.4 3.2 2.2 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions RCC1 PF00415.18 OAJ23925.1 - 6.1e-23 81.2 3.2 5e-05 23.8 0.0 7.2 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ23925.1 - 2.1e-15 56.1 11.1 8.1e-05 22.3 0.1 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 OAJ23925.1 - 0.02 15.1 0.2 0.17 12.1 0.0 2.8 2 1 0 2 2 2 0 Putative heavy-metal chelation CarbpepA_inh PF02977.15 OAJ23926.1 - 0.03 14.1 1.7 0.03 14.1 1.7 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Hydrophobin PF01185.18 OAJ23926.1 - 0.049 14.3 1.0 0.049 14.3 1.0 2.0 1 1 1 2 2 2 0 Fungal hydrophobin Aminotran_1_2 PF00155.21 OAJ23927.1 - 3.6e-58 197.5 0.0 4.8e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-Tim10_DDP PF02953.15 OAJ23928.1 - 1.2e-21 76.1 1.8 1.6e-21 75.7 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.20 OAJ23928.1 - 0.011 15.8 0.2 0.015 15.4 0.2 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FANCI_S3 PF14677.6 OAJ23928.1 - 0.016 15.0 0.6 0.019 14.7 0.6 1.1 1 0 0 1 1 1 0 FANCI solenoid 3 Herpes_UL42 PF02282.16 OAJ23928.1 - 0.045 13.6 0.1 0.059 13.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) WD40 PF00400.32 OAJ23930.1 - 3.6e-08 33.9 9.4 0.12 13.3 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ArfGap PF01412.18 OAJ23931.1 - 1.2e-31 109.2 0.7 2.3e-31 108.3 0.7 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OAJ23931.1 - 3.3e-08 34.0 0.0 7.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1724 PF08350.10 OAJ23931.1 - 0.078 13.1 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) FAD_binding_4 PF01565.23 OAJ23932.1 - 4e-16 59.0 1.7 7e-16 58.2 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ23932.1 - 3.3e-09 36.7 0.4 7.5e-09 35.6 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Mito_carr PF00153.27 OAJ23938.1 - 3.5e-60 199.9 3.8 3.9e-21 74.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 OAJ23939.1 - 8.3e-22 77.1 1.4 1.3e-21 76.4 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain Acid_PPase PF12689.7 OAJ23940.1 - 2.9e-52 176.9 0.0 3.5e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 OAJ23940.1 - 0.022 14.8 0.0 3.8 7.6 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NIF PF03031.18 OAJ23940.1 - 0.068 12.9 0.0 0.34 10.7 0.0 1.9 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase RGS PF00615.19 OAJ23941.1 - 4.1e-36 123.8 0.1 1e-25 90.3 0.0 3.5 3 1 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.21 OAJ23941.1 - 1.1e-13 51.0 0.1 5e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Hist_deacetyl PF00850.19 OAJ23942.1 - 5.2e-85 285.6 0.0 7.7e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 OAJ23942.1 - 1.3e-29 103.1 0.1 6.6e-12 45.1 0.0 3.1 3 0 0 3 3 3 3 Arb2 domain DPBB_1 PF03330.18 OAJ23943.1 - 2.1e-10 40.7 0.1 4.6e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Lytic transglycolase SDA1 PF05285.12 OAJ23943.1 - 0.0094 15.4 11.5 0.012 15.0 11.5 1.1 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 OAJ23943.1 - 0.02 14.5 11.9 0.031 13.9 11.9 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OAJ23943.1 - 0.078 11.2 16.1 0.097 10.9 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAJ23943.1 - 0.44 9.8 21.2 0.7 9.2 21.2 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 OAJ23943.1 - 0.81 9.9 17.4 1.6 8.9 17.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 OAJ23943.1 - 0.98 7.4 23.1 1.3 7.0 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAJ23943.1 - 1 9.1 20.6 1.7 8.4 20.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 OAJ23943.1 - 2.2 6.5 9.3 2.7 6.2 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 OAJ23943.1 - 8.5 5.6 19.4 12 5.2 19.4 1.1 1 0 0 1 1 1 0 BUD22 EF_assoc_1 PF08355.12 OAJ23944.1 - 3e-05 23.5 0.0 6.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated BSP_II PF05432.11 OAJ23944.1 - 0.00049 19.9 2.0 0.00077 19.2 2.0 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) EF_assoc_2 PF08356.12 OAJ23944.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Apt1 PF10351.9 OAJ23944.1 - 0.33 9.8 5.2 0.38 9.6 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 OAJ23944.1 - 0.72 9.4 2.9 1.1 8.8 2.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4637 PF15470.6 OAJ23944.1 - 1 9.1 6.3 1.8 8.3 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Rrn6 PF10214.9 OAJ23944.1 - 1.2 7.5 13.5 1.7 7.1 13.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BUD22 PF09073.10 OAJ23944.1 - 3.1 7.1 11.5 4.3 6.6 11.5 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 OAJ23944.1 - 3.5 7.5 11.5 4.7 7.0 11.5 1.2 1 0 0 1 1 1 0 SPX domain KH_6 PF15985.5 OAJ23945.1 - 2.5e-09 37.3 0.0 4.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 OAJ23945.1 - 1e-06 28.5 2.9 7.3e-06 25.8 1.4 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain Tub_N PF16322.5 OAJ23945.1 - 1 9.7 3.1 0.4 11.0 0.5 1.6 2 0 0 2 2 2 0 Tubby N-terminal Macoilin PF09726.9 OAJ23946.1 - 1.3 7.4 5.0 1.7 7.1 5.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 OAJ23946.1 - 3.5 6.3 6.6 4 6.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nitroreductase PF00881.24 OAJ23947.1 - 5.1e-11 42.9 0.0 6.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1688 PF07958.11 OAJ23948.1 - 1.8e-152 507.9 0.0 7.3e-151 502.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) HK PF02110.15 OAJ23949.1 - 9.8e-58 195.4 9.5 2.8e-56 190.7 6.0 2.6 2 1 1 3 3 3 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAJ23949.1 - 8.8e-44 149.0 0.1 1.4e-42 145.1 0.1 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 OAJ23949.1 - 2.5e-07 30.4 0.8 4.2e-07 29.6 0.8 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Actin PF00022.19 OAJ23950.1 - 2.5e-26 92.2 0.0 2e-16 59.6 0.0 3.8 3 1 0 3 3 3 2 Actin Sporozoite_P67 PF05642.11 OAJ23950.1 - 1.1 7.3 9.3 0.18 9.9 4.7 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen bZIP_1 PF00170.21 OAJ23951.1 - 3e-05 24.0 4.3 8e-05 22.7 4.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ23951.1 - 0.00026 21.0 4.9 0.00053 20.0 4.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_BLRF2 PF05812.12 OAJ23951.1 - 0.023 14.8 2.0 0.13 12.5 2.0 2.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein LCD1 PF09798.9 OAJ23951.1 - 0.041 12.4 0.1 0.054 12.0 0.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Allexi_40kDa PF05549.11 OAJ23951.1 - 0.07 12.6 0.9 0.2 11.1 0.9 1.8 1 0 0 1 1 1 0 Allexivirus 40kDa protein Uso1_p115_C PF04871.13 OAJ23951.1 - 0.077 13.4 1.7 0.24 11.8 1.7 1.8 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc24 PF08286.11 OAJ23951.1 - 0.13 12.6 0.6 0.27 11.5 0.6 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SHE3 PF17078.5 OAJ23951.1 - 0.64 9.7 3.9 0.27 10.9 0.9 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Pkinase PF00069.25 OAJ23952.1 - 7.1e-60 202.6 0.0 2.8e-40 138.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23952.1 - 5.7e-26 91.4 0.0 9.3e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAJ23952.1 - 2.2e-10 40.7 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAJ23952.1 - 2.2e-07 30.5 0.0 2.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ23952.1 - 0.00068 19.6 0.0 0.012 15.5 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ23952.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_4 PF08448.10 OAJ23952.1 - 0.021 15.1 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold Kdo PF06293.14 OAJ23952.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ23952.1 - 0.024 14.3 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAJ23952.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family OKR_DC_1_N PF03709.15 OAJ23952.1 - 0.18 12.1 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PALP PF00291.25 OAJ23953.1 - 6.3e-48 163.7 6.7 1.4e-46 159.3 6.7 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 OAJ23953.1 - 0.082 12.7 0.5 0.19 11.6 0.5 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RVT_1 PF00078.27 OAJ23954.1 - 1.2e-24 87.1 0.0 2.1e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ23954.1 - 6.9e-21 74.2 0.0 1.6e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ23954.1 - 1.1e-15 57.8 0.0 7.3e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ23954.1 - 3.6e-15 55.8 0.5 6.4e-15 55.0 0.5 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ23954.1 - 4.3e-11 43.0 0.0 1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ23954.1 - 0.00021 21.9 0.0 0.00064 20.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ23954.1 - 0.014 16.0 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease NCA2 PF08637.10 OAJ23960.1 - 1.5e-75 254.0 0.0 3.2e-75 253.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Thioredoxin_13 PF18401.1 OAJ23960.1 - 0.1 12.5 0.3 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like domain Nrap_D4 PF17405.2 OAJ23961.1 - 1.6e-53 181.2 0.0 2.8e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 OAJ23961.1 - 2.5e-44 151.0 0.0 4.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 OAJ23961.1 - 7.4e-39 132.9 0.1 6.2e-38 129.9 0.0 2.4 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 OAJ23961.1 - 1.8e-37 128.9 0.0 3.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 OAJ23961.1 - 1.7e-34 119.0 0.0 4.7e-34 117.5 0.0 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 OAJ23961.1 - 1.2e-26 93.5 0.0 3e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 6 BUD22 PF09073.10 OAJ23961.1 - 0.051 12.9 30.2 0.077 12.3 30.2 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OAJ23961.1 - 0.28 10.6 25.0 0.5 9.7 25.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ23961.1 - 0.39 8.9 26.1 0.55 8.4 26.1 1.1 1 0 0 1 1 1 0 Nop14-like family FAD-oxidase_C PF02913.19 OAJ23962.1 - 3.6e-53 180.8 0.1 1.1e-52 179.2 0.1 1.7 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAJ23962.1 - 1.4e-25 89.6 0.0 7.9e-25 87.2 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ23962.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Acyl-thio_N PF12590.8 OAJ23963.1 - 0.029 15.0 1.4 0.029 15.0 1.4 1.7 2 0 0 2 2 2 0 Acyl-ATP thioesterase Apt1 PF10351.9 OAJ23963.1 - 0.2 10.5 5.7 0.23 10.3 5.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 OAJ23963.1 - 7.3 4.7 13.3 7.8 4.6 13.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_membrane PF00664.23 OAJ23967.1 - 3.4e-62 210.6 21.1 3.9e-38 131.7 8.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ23967.1 - 2.7e-50 170.4 0.0 5.5e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OAJ23967.1 - 2.8e-06 27.0 0.1 0.037 13.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ23967.1 - 3e-06 27.3 0.2 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 OAJ23967.1 - 8.3e-06 25.4 1.7 0.63 9.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ23967.1 - 0.00015 22.2 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ23967.1 - 0.00041 20.3 0.1 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAJ23967.1 - 0.00094 19.1 0.0 0.52 10.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ23967.1 - 0.00099 19.7 5.0 0.36 11.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 OAJ23967.1 - 0.0056 16.4 0.2 2.8 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 OAJ23967.1 - 0.0072 15.9 0.2 0.37 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ23967.1 - 0.012 14.9 1.0 0.24 10.7 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 OAJ23967.1 - 0.026 14.6 7.2 0.45 10.6 0.0 3.1 4 0 0 4 4 2 0 Dynamin family IstB_IS21 PF01695.17 OAJ23967.1 - 0.038 13.7 0.1 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAJ23967.1 - 0.051 13.3 3.8 1.7 8.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.14 OAJ23968.1 - 2.8e-59 201.1 0.6 2.9e-46 158.3 0.1 2.1 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 OAJ23968.1 - 2.1e-22 79.8 0.0 3.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ23968.1 - 4.9e-12 46.4 0.0 8.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ23968.1 - 5.7e-06 26.7 0.0 1.9e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ23968.1 - 2.8e-05 23.7 0.1 0.00014 21.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OAJ23968.1 - 0.00051 19.8 0.1 0.57 9.9 0.1 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAJ23968.1 - 0.00075 19.3 0.5 0.0064 16.3 0.2 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 OAJ23968.1 - 0.0018 17.4 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 OAJ23968.1 - 0.0022 17.3 0.0 0.0043 16.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OAJ23968.1 - 0.0033 17.8 0.1 0.0082 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAJ23968.1 - 0.0036 17.7 0.0 0.0077 16.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 OAJ23968.1 - 0.0072 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 OAJ23968.1 - 0.0097 15.8 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain SH3_13 PF18335.1 OAJ23968.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ATPase_2 PF01637.18 OAJ23968.1 - 0.034 14.1 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 OAJ23968.1 - 0.038 13.7 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 OAJ23968.1 - 0.038 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.14 OAJ23968.1 - 0.046 11.7 0.1 0.49 8.2 0.0 2.1 2 0 0 2 2 2 0 Helicase NB-ARC PF00931.22 OAJ23968.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 OAJ23968.1 - 0.059 13.4 0.0 0.41 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAJ23968.1 - 0.066 12.6 0.1 0.28 10.6 0.1 1.8 1 1 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 OAJ23968.1 - 0.084 12.6 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OAJ23968.1 - 0.092 12.6 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 OAJ23968.1 - 0.13 12.2 0.2 1.1 9.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 OAJ23968.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NAD_kinase PF01513.21 OAJ23969.1 - 7.4e-53 179.6 0.0 9.3e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAJ23969.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain E1-E2_ATPase PF00122.20 OAJ23970.1 - 8.7e-27 93.8 0.0 2.6e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 OAJ23970.1 - 4.2e-26 91.5 0.0 5e-23 81.6 0.0 2.4 2 0 0 2 2 2 2 P5-type ATPase cation transporter Hydrolase PF00702.26 OAJ23970.1 - 1.4e-16 61.4 0.4 2.9e-08 34.3 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 OAJ23970.1 - 1.1e-06 28.5 10.0 2.8e-06 27.2 10.0 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAJ23970.1 - 8.5e-05 22.6 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ23970.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Sortilin-Vps10 PF15902.5 OAJ23971.1 - 4e-135 451.1 0.0 4.9e-135 450.8 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAJ23971.1 - 2.6e-40 138.5 1.6 2.6e-40 138.5 1.6 1.6 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal CHB_HEX_C PF03174.13 OAJ23971.1 - 0.001 19.0 0.4 2 8.5 0.0 3.5 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain F5_F8_type_C PF00754.25 OAJ23971.1 - 0.066 13.3 1.0 4.2 7.5 0.0 4.0 6 0 0 6 6 6 0 F5/8 type C domain Macoilin PF09726.9 OAJ23972.1 - 0.089 11.3 1.3 0.19 10.2 1.3 1.4 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 OAJ23973.1 - 6.1e-81 272.6 17.0 7.9e-50 170.0 0.0 4.5 3 2 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 OAJ23973.1 - 0.00087 18.2 1.4 0.62 8.8 0.0 2.9 3 0 0 3 3 3 2 Nitrogen permease regulator 2 PTPLA PF04387.14 OAJ23974.1 - 4.5e-50 169.6 6.5 4.5e-50 169.6 6.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA ATG101 PF07855.12 OAJ23975.1 - 9.5e-18 64.6 0.0 1.3e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Autophagy-related protein 101 Ribosomal_L27A PF00828.19 OAJ23976.1 - 9.6e-35 120.1 0.0 1.4e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Romo1 PF10247.9 OAJ23982.1 - 3.9e-20 72.0 15.7 5.9e-20 71.4 15.7 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pex14_N PF04695.13 OAJ23982.1 - 0.04 14.6 11.0 0.066 13.9 11.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SARAF PF06682.12 OAJ23982.1 - 0.072 12.7 4.0 0.099 12.3 4.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CPP1-like PF11833.8 OAJ23982.1 - 0.074 12.7 1.1 0.13 11.9 1.1 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CCDC53 PF10152.9 OAJ23982.1 - 0.77 10.2 5.8 1.1 9.7 5.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_M28 PF04389.17 OAJ23983.1 - 9.7e-33 113.5 0.0 3.3e-32 111.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Lectin_N PF03954.14 OAJ23983.1 - 0.23 11.2 0.2 0.39 10.5 0.2 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DOT1 PF08123.13 OAJ23985.1 - 6.2e-65 218.6 0.0 8.3e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 ABC_membrane PF00664.23 OAJ23987.1 - 3.7e-51 174.4 0.8 4.8e-51 174.0 0.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ23987.1 - 1.6e-31 109.6 0.0 5e-31 108.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OAJ23987.1 - 0.0016 18.8 0.3 0.0081 16.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 OAJ23987.1 - 0.0016 17.9 0.5 0.052 13.0 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 OAJ23987.1 - 0.006 17.0 0.0 0.09 13.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ23987.1 - 0.016 15.5 0.0 0.11 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 OAJ23987.1 - 0.023 13.5 0.5 0.036 12.9 0.0 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OAJ23987.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 OAJ23987.1 - 0.038 14.0 0.0 0.83 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 OAJ23987.1 - 0.046 13.5 0.2 5.2 6.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_polI_A34 PF08208.11 OAJ23988.1 - 1.9e-12 47.7 21.8 1.9e-12 47.7 21.8 2.3 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 TFIIA PF03153.13 OAJ23988.1 - 0.0029 17.7 14.8 0.0043 17.1 14.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 OAJ23988.1 - 0.025 14.0 28.6 0.032 13.6 28.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SID-1_RNA_chan PF13965.6 OAJ23988.1 - 1.5 7.1 2.3 1.5 7.2 2.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HMG_box PF00505.19 OAJ23989.1 - 1.6e-11 44.5 0.3 2.8e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ23989.1 - 2.7e-10 40.7 0.3 5.5e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain PXA PF02194.15 OAJ23991.1 - 1.2e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 OAJ23991.1 - 1.1e-12 48.5 0.0 3e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.9 OAJ23991.1 - 0.49 10.4 2.0 0.89 9.6 2.0 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DSPc PF00782.20 OAJ23992.1 - 2.6e-16 59.7 0.0 1.1e-14 54.3 0.2 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ23992.1 - 0.027 14.0 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase WD40 PF00400.32 OAJ23993.1 - 4.1e-07 30.6 4.4 0.11 13.4 0.3 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat YL1 PF05764.13 OAJ23993.1 - 5.3 7.1 27.5 2 8.5 15.1 2.7 3 0 0 3 3 3 0 YL1 nuclear protein CENP-F_leu_zip PF10473.9 OAJ23994.1 - 0.0013 18.8 1.2 0.0017 18.4 1.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc29 PF17082.5 OAJ23994.1 - 0.0092 15.9 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 Cnn_1N PF07989.11 OAJ23994.1 - 0.016 15.3 3.1 0.016 15.3 3.1 1.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 OAJ23994.1 - 0.021 15.4 3.2 0.035 14.6 3.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3410 PF11890.8 OAJ23994.1 - 0.081 12.7 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DivIC PF04977.15 OAJ23994.1 - 0.086 12.6 4.9 0.13 12.1 4.1 1.6 1 1 1 2 2 2 0 Septum formation initiator VGPC1_C PF16799.5 OAJ23994.1 - 0.16 12.0 1.9 0.26 11.3 0.2 2.0 1 1 1 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 adh_short PF00106.25 OAJ23996.1 - 1.7e-15 57.0 0.3 6.6e-14 51.8 0.8 2.6 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ23996.1 - 3.4e-07 30.0 1.2 0.022 14.3 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ23996.1 - 0.00021 21.2 3.2 0.0017 18.3 0.5 2.2 2 0 0 2 2 2 1 KR domain TPR_8 PF13181.6 OAJ23997.1 - 0.003 17.6 0.0 0.027 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ23997.1 - 0.1 12.7 0.3 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 OAJ23997.1 - 0.16 12.3 5.3 0.24 11.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Myotub-related PF06602.14 OAJ23998.1 - 4.8e-141 469.8 0.0 9.4e-141 468.8 0.0 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain UCH PF00443.29 OAJ23999.1 - 4.9e-42 144.2 0.0 2.1e-41 142.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ23999.1 - 2.4e-20 73.4 0.1 1.6e-10 41.1 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ23999.1 - 1.9e-08 34.5 1.0 1.9e-08 34.5 1.0 3.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein PBP1_TM PF14812.6 OAJ23999.1 - 4.5 7.7 14.8 1 9.8 6.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 OAJ23999.1 - 4.6 7.5 11.5 10 6.4 6.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 OAJ23999.1 - 6 6.6 7.3 0.82 9.4 1.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RabGAP-TBC PF00566.18 OAJ24000.1 - 4e-43 147.6 0.2 5.4e-43 147.2 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Importin_rep_3 PF18806.1 OAJ24004.1 - 0.085 12.9 0.2 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Importin 13 repeat I_LWEQ PF01608.17 OAJ24004.1 - 0.21 11.8 0.9 2.7 8.2 0.0 2.4 2 1 0 2 2 2 0 I/LWEQ domain EB PF01683.18 OAJ24005.1 - 0.018 15.3 2.3 0.018 15.3 2.3 3.8 3 2 0 3 3 3 0 EB module Dickkopf_N PF04706.12 OAJ24005.1 - 0.026 15.0 31.6 0.31 11.5 7.1 3.7 2 1 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF2721 PF11026.8 OAJ24006.1 - 0.018 14.9 0.4 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2207 PF09972.9 OAJ24006.1 - 0.042 12.6 0.0 2.3 6.9 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF5319 PF17252.2 OAJ24006.1 - 0.044 14.0 0.2 0.077 13.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Sporozoite_P67 PF05642.11 OAJ24007.1 - 1.4 6.9 10.4 1.7 6.6 10.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NUDE_C PF04880.13 OAJ24007.1 - 6.2 7.3 7.6 11 6.5 7.6 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region RRF PF01765.19 OAJ24008.1 - 2.7e-32 112.0 0.1 4.5e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Ribosomal_S6 PF01250.17 OAJ24008.1 - 0.16 12.3 0.2 0.66 10.3 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein S6 PBP1_TM PF14812.6 OAJ24008.1 - 4.2 7.8 13.2 0.12 12.8 6.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tho2 PF11262.8 OAJ24008.1 - 4.4 6.4 5.4 7.2 5.7 5.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3446 PF11928.8 OAJ24009.1 - 0.12 12.7 2.8 0.24 11.7 1.9 1.7 1 1 1 2 2 2 0 Early growth response N-terminal domain VCBS PF13517.6 OAJ24011.1 - 5.8e-20 71.6 13.6 3.4e-06 27.5 0.5 5.5 3 2 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OAJ24011.1 - 4.8e-09 36.2 4.9 0.0035 17.4 0.0 5.7 5 0 0 5 5 5 3 FG-GAP repeat zf-CCHC PF00098.23 OAJ24012.1 - 7.6e-48 158.5 63.9 2.8e-07 30.3 2.1 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ24012.1 - 7.1e-12 45.1 31.1 0.11 12.5 0.0 7.0 4 2 2 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ24012.1 - 2.8e-11 43.0 43.2 0.019 14.7 1.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ24012.1 - 5.5e-05 22.9 12.3 0.0017 18.2 0.7 7.1 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ24012.1 - 0.00043 19.9 36.9 0.19 11.5 0.7 7.0 7 0 0 7 7 7 5 GAG-polyprotein viral zinc-finger DUF3446 PF11928.8 OAJ24013.1 - 0.0056 17.0 0.3 0.009 16.3 0.3 1.3 1 0 0 1 1 1 1 Early growth response N-terminal domain Tuberculin PF12198.8 OAJ24014.1 - 0.085 13.0 3.8 0.14 12.3 3.8 1.3 1 0 0 1 1 1 0 Theoretical tuberculin protein NUC153 PF08159.12 OAJ24015.1 - 1.6e-10 40.6 7.1 1.4e-09 37.5 0.0 3.5 3 0 0 3 3 3 1 NUC153 domain TMEM51 PF15345.6 OAJ24015.1 - 0.023 14.5 0.9 0.023 14.5 0.9 2.7 3 1 0 3 3 3 0 Transmembrane protein 51 Ank_2 PF12796.7 OAJ24016.1 - 1.9e-50 169.4 0.0 2.1e-19 69.9 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ24016.1 - 3.6e-35 119.9 1.5 2e-12 47.4 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ24016.1 - 6.5e-34 115.6 1.1 1e-10 41.7 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ24016.1 - 3.1e-22 76.3 0.6 0.00024 21.3 0.0 5.5 5 0 0 5 5 4 4 Ankyrin repeat Ank PF00023.30 OAJ24016.1 - 2.5e-18 65.6 0.1 0.00068 20.0 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 OAJ24016.1 - 2.7e-18 65.9 9.7 2.7e-18 65.9 9.7 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 OAJ24016.1 - 3.5e-08 33.6 3.3 3.5e-08 33.6 3.3 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OAJ24016.1 - 6.2e-05 22.7 4.6 0.00016 21.4 4.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ24016.1 - 0.00037 20.3 2.7 0.00037 20.3 2.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ24016.1 - 0.01 16.1 2.5 0.01 16.1 2.5 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAJ24016.1 - 0.013 15.5 3.3 0.013 15.5 3.3 2.6 3 0 0 3 3 2 0 RING-type zinc-finger CMS1 PF14617.6 OAJ24016.1 - 0.064 12.6 0.0 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FYVE_2 PF02318.16 OAJ24016.1 - 0.17 12.1 7.7 0.073 13.3 2.8 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.19 OAJ24016.1 - 1.8 8.6 4.3 17 5.4 4.3 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FANCL_C PF11793.8 OAJ24016.1 - 2.6 8.3 6.0 1.2 9.4 2.7 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain Exo70 PF03081.15 OAJ24018.1 - 3.1e-52 177.9 0.0 1.2e-51 175.9 0.0 1.8 1 1 0 1 1 1 1 Exo70 exocyst complex subunit Vps52 PF04129.12 OAJ24018.1 - 0.013 14.2 0.1 0.16 10.7 0.0 2.4 3 0 0 3 3 3 0 Vps52 / Sac2 family Baculo_PEP_C PF04513.12 OAJ24018.1 - 0.046 13.8 0.2 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 OAJ24018.1 - 0.097 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Sec34-like family FmiP_Thoc5 PF09766.9 OAJ24018.1 - 0.24 10.6 0.1 0.39 10.0 0.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Cauli_VI PF01693.16 OAJ24020.1 - 4.5e-15 55.7 1.7 8.1e-15 54.9 1.7 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Helicase_C PF00271.31 OAJ24021.1 - 2.7e-14 53.4 0.0 5.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 OAJ24021.1 - 0.00019 21.5 0.1 0.0005 20.2 0.1 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain SR-25 PF10500.9 OAJ24021.1 - 0.31 10.6 3.7 0.54 9.8 3.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_10 PF13374.6 OAJ24022.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat RNase_H PF00075.24 OAJ24023.1 - 4.9e-33 114.3 0.0 6.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 OAJ24023.1 - 1.6e-20 73.1 0.2 2.8e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin SUI1 PF01253.22 OAJ24025.1 - 2.2e-30 105.0 0.4 3.4e-30 104.4 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribonuclease_3 PF00636.26 OAJ24026.1 - 0.015 15.9 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain Fe_hyd_lg_C PF02906.14 OAJ24027.1 - 7e-54 183.1 0.0 1.7e-53 181.8 0.0 1.6 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HSP70 PF00012.20 OAJ24030.1 - 5.1e-157 523.7 0.1 6.5e-157 523.3 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ24030.1 - 2.4e-08 33.2 0.1 1.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Not1 PF04054.15 OAJ24032.1 - 5.1e-117 390.9 0.0 1.7e-116 389.2 0.0 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAJ24032.1 - 3e-95 317.9 0.0 5.8e-94 313.7 0.2 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAJ24032.1 - 3.4e-57 192.5 3.6 7.1e-57 191.4 3.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAJ24032.1 - 7.9e-54 181.7 0.2 2.3e-53 180.2 0.2 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAJ24032.1 - 1.9e-45 154.6 1.8 1.9e-45 154.6 1.8 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FerA PF08165.11 OAJ24032.1 - 0.092 12.7 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 FerA (NUC095) domain Usp PF00582.26 OAJ24033.1 - 2.2e-19 70.4 6.8 5.1e-19 69.2 0.1 3.3 3 0 0 3 3 3 2 Universal stress protein family DER1 PF04511.15 OAJ24037.1 - 8.7e-48 162.8 2.5 9.9e-48 162.6 2.5 1.0 1 0 0 1 1 1 1 Der1-like family CitMHS PF03600.16 OAJ24037.1 - 0.06 12.5 0.5 0.07 12.3 0.5 1.2 1 0 0 1 1 1 0 Citrate transporter DUF2070 PF09843.9 OAJ24037.1 - 0.072 11.4 3.0 0.08 11.2 3.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGAP PF00620.27 OAJ24038.1 - 1.6e-38 131.9 0.0 3.7e-38 130.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 OAJ24038.1 - 2.8e-14 53.7 0.0 1.2e-12 48.4 0.0 2.7 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OAJ24038.1 - 4.4e-09 36.5 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.6 OAJ24038.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ24038.1 - 0.0024 18.4 0.0 0.36 11.4 0.0 2.4 2 0 0 2 2 2 1 PH domain RdgC PF04381.12 OAJ24038.1 - 0.093 12.0 0.3 0.2 10.9 0.3 1.5 1 0 0 1 1 1 0 Putative exonuclease, RdgC SPESP1 PF15754.5 OAJ24038.1 - 0.1 11.7 0.2 0.22 10.7 0.2 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 OAJ24038.1 - 0.94 9.5 11.6 0.18 11.8 7.3 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) R3H PF01424.22 OAJ24039.1 - 6.9e-14 51.6 0.2 1.1e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 R3H domain FliN_N PF16973.5 OAJ24039.1 - 0.065 13.1 0.4 0.27 11.1 0.4 2.0 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal SHNi-TPR PF10516.9 OAJ24040.1 - 0.00035 19.9 0.8 0.00035 19.9 0.8 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 OAJ24040.1 - 0.00055 19.9 7.7 0.39 10.9 1.2 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat Sigma70_ner PF04546.13 OAJ24040.1 - 0.0056 16.6 1.4 0.0056 16.6 1.4 2.6 3 0 0 3 3 3 1 Sigma-70, non-essential region YceD PF02620.17 OAJ24040.1 - 0.052 13.7 1.7 0.069 13.3 0.1 2.0 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD TPR_17 PF13431.6 OAJ24040.1 - 0.066 13.6 0.1 66 4.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ24040.1 - 0.092 12.6 4.1 6.7 6.7 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ24040.1 - 0.098 12.8 5.3 7.3 6.8 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 OAJ24040.1 - 0.38 8.8 6.6 0.64 8.0 6.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ24040.1 - 0.5 9.6 9.2 0.91 8.8 9.2 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_14 PF13428.6 OAJ24040.1 - 0.51 11.3 10.7 1.6 9.8 0.9 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat MSP1_C PF07462.11 OAJ24040.1 - 1.4 7.5 3.0 3 6.4 3.0 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TPR_12 PF13424.6 OAJ24040.1 - 1.4 9.2 12.8 1.1 9.6 0.7 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Tubulin PF00091.25 OAJ24041.1 - 1.6e-68 230.8 0.0 2.4e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ24041.1 - 7.4e-41 139.2 0.0 1.4e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ24041.1 - 0.00094 19.5 0.0 0.0025 18.1 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ24041.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain zf-C3HC4_3 PF13920.6 OAJ24042.1 - 0.00062 19.6 2.8 0.0013 18.6 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ24042.1 - 0.00071 19.9 6.6 0.0012 19.1 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ24042.1 - 0.0028 17.5 5.2 0.0048 16.7 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C2 PF00168.30 OAJ24043.1 - 1.5e-25 89.5 0.0 1.5e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain Flagellin_IN PF07196.13 OAJ24043.1 - 0.096 12.9 0.5 0.51 10.6 0.1 2.4 2 0 0 2 2 2 0 Flagellin hook IN motif WD40 PF00400.32 OAJ24046.1 - 3.4e-30 103.6 19.3 2.1e-06 28.3 1.5 9.5 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24046.1 - 2.7e-07 30.8 1.2 0.077 13.3 0.0 5.5 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ24046.1 - 5.2e-05 22.4 0.1 1 8.3 0.0 4.0 5 0 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_2b PF00587.25 OAJ24047.1 - 2.4e-29 102.6 0.0 5.1e-29 101.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ24047.1 - 0.00013 22.1 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Transposase_21 PF02992.14 OAJ24048.1 - 0.055 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Kinesin PF00225.23 OAJ24050.1 - 4.2e-110 367.8 0.0 7.2e-110 367.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 OAJ24050.1 - 2.6e-41 141.7 4.6 7.2e-33 114.2 1.2 3.2 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 OAJ24050.1 - 2.2e-33 116.1 0.1 7.9e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 OAJ24050.1 - 3.7e-25 88.6 0.0 8.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 OAJ24050.1 - 4.2e-16 59.4 0.1 1.3e-15 57.8 0.1 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 OAJ24050.1 - 1.9e-09 37.8 0.1 5.7e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 OAJ24050.1 - 1.1e-05 25.7 0.0 4.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.6 OAJ24050.1 - 0.062 13.7 0.1 0.25 11.8 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain RVT_1 PF00078.27 OAJ24051.1 - 2.3e-21 76.4 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ24051.1 - 4.7e-19 68.3 0.0 4.7e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ24051.1 - 3.1e-15 56.0 0.0 6.7e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ24051.1 - 1.1e-13 51.4 0.0 2.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ24051.1 - 5.2e-07 29.9 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ24051.1 - 0.0038 17.8 0.1 0.012 16.2 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ24051.1 - 0.031 14.5 0.1 0.08 13.2 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 OAJ24051.1 - 0.14 12.5 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag_pre-integrs PF13976.6 OAJ24052.1 - 9.3e-06 25.4 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF2451 PF10474.9 OAJ24052.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) RVT_2 PF07727.14 OAJ24053.1 - 9.9e-61 205.5 0.0 1.3e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ24053.1 - 0.00045 20.0 0.1 0.0013 18.5 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Cys_Met_Meta_PP PF01053.20 OAJ24054.1 - 1.7e-59 201.3 0.0 1.9e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 OAJ24055.1 - 1e-36 124.3 12.4 2.7e-07 31.2 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24055.1 - 5.3e-11 42.7 0.1 0.016 15.5 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAJ24055.1 - 0.0017 16.9 0.0 0.59 8.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain VID27 PF08553.10 OAJ24055.1 - 0.12 11.5 0.1 0.24 10.4 0.1 1.4 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain FA_desaturase PF00487.24 OAJ24056.1 - 2.2e-05 24.4 16.0 2.2e-05 24.4 16.0 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Tim29 PF10171.9 OAJ24057.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.4 1 1 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 LETM1 PF07766.13 OAJ24059.1 - 1.5e-100 336.0 1.7 1.5e-100 336.0 1.7 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 OAJ24059.1 - 2.1e-05 24.9 3.8 0.0036 17.7 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 OAJ24059.1 - 0.0033 17.2 2.2 3.8 7.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OAJ24059.1 - 0.0066 16.3 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OAJ24059.1 - 0.094 12.3 2.8 4.1 7.2 0.0 3.5 4 0 0 4 4 4 0 EF hand DUF1682 PF07946.14 OAJ24059.1 - 0.38 9.9 9.9 0.66 9.1 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ALMT PF11744.8 OAJ24059.1 - 0.87 8.3 9.8 1.4 7.7 9.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Rot1 PF10681.9 OAJ24060.1 - 1.3e-55 188.2 0.9 1.6e-55 187.9 0.9 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal NAD_synthase PF02540.17 OAJ24061.1 - 2.6e-23 82.4 0.0 1.3e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.22 OAJ24061.1 - 4e-21 75.5 0.0 6.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CcmD PF04995.14 OAJ24063.1 - 0.19 11.9 0.6 0.36 11.0 0.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pox_Ag35 PF03286.14 OAJ24063.1 - 4.9 6.9 9.1 0.43 10.3 3.9 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein LETM1 PF07766.13 OAJ24065.1 - 1.7e-19 70.2 0.1 1.8e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 LETM1-like protein RAP1 PF07218.11 OAJ24065.1 - 7.3 4.7 7.7 14 3.8 7.7 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fas_alpha_ACP PF18325.1 OAJ24066.1 - 5.8e-30 104.8 0.0 1.7e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 OAJ24066.1 - 1e-22 80.9 1.0 2.5e-22 79.7 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAJ24066.1 - 3.2e-17 62.6 0.6 8.3e-17 61.3 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain FAS_I_H PF18314.1 OAJ24066.1 - 2.5e-14 53.4 0.0 6.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ACPS PF01648.20 OAJ24066.1 - 5.1e-14 52.4 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 OAJ24066.1 - 5.5e-10 39.0 0.1 5.6e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24066.1 - 3.3e-08 33.4 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ24066.1 - 3.9e-05 23.6 0.3 0.0042 17.0 0.0 2.6 2 0 0 2 2 2 1 KR domain Thiolase_N PF00108.23 OAJ24066.1 - 0.011 15.1 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain RNA_pol_Rpc34 PF05158.12 OAJ24067.1 - 1.5e-73 248.1 2.7 3.2e-64 217.4 0.6 2.4 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit SOG2 PF10428.9 OAJ24067.1 - 0.046 12.9 36.1 0.074 12.2 36.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein MRC1 PF09444.10 OAJ24068.1 - 3.3e-19 69.8 24.4 3.3e-19 69.8 24.4 6.0 6 1 0 6 6 6 1 MRC1-like domain GP38 PF05268.11 OAJ24068.1 - 0.79 9.3 10.9 1.3 8.6 10.9 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Jnk-SapK_ap_N PF09744.9 OAJ24069.1 - 0.0089 16.3 0.5 0.011 16.0 0.5 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ZapB PF06005.12 OAJ24069.1 - 0.15 12.5 4.4 0.21 12.1 4.4 1.1 1 0 0 1 1 1 0 Cell division protein ZapB LapA_dom PF06305.11 OAJ24069.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DDE_Tnp_4 PF13359.6 OAJ24071.1 - 1e-20 74.0 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ24071.1 - 8.3e-11 41.9 0.0 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ24071.1 - 2.1e-07 30.8 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAJ24071.1 - 0.11 12.8 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain Acetyltransf_2 PF00797.17 OAJ24071.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase Myb_DNA-bind_3 PF12776.7 OAJ24072.1 - 3.3e-15 56.8 5.7 3.5e-15 56.8 2.1 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ24072.1 - 6.3e-06 26.5 0.7 1.8e-05 25.0 0.7 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ24072.1 - 0.13 12.5 0.2 0.37 11.1 0.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain NAM-associated PF14303.6 OAJ24072.1 - 1.7 9.3 19.2 3.2 8.4 5.0 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 OAJ24072.1 - 5.3 6.6 23.3 0.068 12.8 6.5 2.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein GST_C_2 PF13410.6 OAJ24073.1 - 3.2e-07 30.3 1.3 5.8e-07 29.4 1.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ24073.1 - 3.8e-06 27.2 0.0 6.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ24073.1 - 2.6e-05 24.4 0.0 4.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAJ24073.1 - 0.0057 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ24073.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L35p PF01632.19 OAJ24074.1 - 4.5e-13 49.5 2.8 9.5e-13 48.4 2.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 HsbA PF12296.8 OAJ24075.1 - 3.2e-13 50.2 6.6 4.4e-13 49.7 6.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.13 OAJ24075.1 - 0.0049 16.8 0.1 0.0059 16.5 0.1 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ FmiP_Thoc5 PF09766.9 OAJ24076.1 - 1.8e-24 86.7 12.3 2.3e-24 86.4 12.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 HAUS-augmin3 PF14932.6 OAJ24076.1 - 5.8 6.4 14.4 6.6 6.2 13.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 HsbA PF12296.8 OAJ24078.1 - 2.2e-14 53.9 3.5 3.7e-14 53.2 3.5 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A PIF1 PF05970.14 OAJ24079.1 - 9.4e-52 176.4 0.0 1.7e-51 175.5 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ24079.1 - 1.5e-29 103.5 0.1 1.5e-29 103.5 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ24079.1 - 5.6e-11 42.5 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ24079.1 - 0.00014 22.2 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ24079.1 - 0.0031 17.4 0.0 0.052 13.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 OAJ24079.1 - 0.013 15.3 0.4 2.3 7.9 0.2 3.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OAJ24079.1 - 0.013 14.8 0.0 0.21 10.8 0.0 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OAJ24079.1 - 0.018 15.5 0.0 0.056 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OAJ24079.1 - 0.025 13.7 0.7 0.058 12.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 OAJ24079.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OAJ24079.1 - 0.07 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 OAJ24079.1 - 0.12 11.3 0.0 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 OAJ24079.1 - 0.14 12.4 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAJ24079.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OAJ24079.1 - 0.37 10.5 2.7 0.3 10.8 0.0 2.2 2 1 0 2 2 1 0 AAA domain Dimer_Tnp_hAT PF05699.14 OAJ24082.1 - 4.6e-09 36.0 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region U1snRNP70_N PF12220.8 OAJ24083.1 - 5e-22 78.4 6.8 9.9e-22 77.4 6.8 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OAJ24083.1 - 2.7e-20 71.9 0.0 7e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ24083.1 - 0.02 15.0 0.0 0.064 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 OAJ24083.1 - 0.23 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif AAA_12 PF13087.6 OAJ24086.1 - 3e-32 111.9 0.0 4.8e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ24086.1 - 1.5e-28 100.3 1.8 6e-27 95.1 1.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ24086.1 - 4.6e-09 36.8 0.0 8.2e-08 32.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ24086.1 - 1.1e-07 31.8 0.1 0.00089 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OAJ24086.1 - 0.00016 21.0 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAJ24086.1 - 0.00042 20.4 0.0 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OAJ24086.1 - 0.0091 15.5 0.0 0.69 9.4 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 OAJ24086.1 - 0.061 13.2 0.0 1 9.2 0.0 2.9 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OAJ24086.1 - 0.14 12.5 0.5 0.85 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Cytochrome_C7 PF14522.6 OAJ24087.1 - 0.12 12.3 1.7 0.26 11.3 1.7 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Pro_CA PF00484.19 OAJ24088.1 - 6.2e-35 120.8 0.1 1.5e-34 119.6 0.1 1.6 1 1 0 1 1 1 1 Carbonic anhydrase Phospholip_A2_2 PF05826.12 OAJ24088.1 - 0.089 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase A2 DUF745 PF05335.13 OAJ24089.1 - 0.0029 17.4 2.6 0.0029 17.4 2.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF745) Zn-ribbon_8 PF09723.10 OAJ24089.1 - 0.8 9.9 3.4 7.3 6.8 0.5 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 OAJ24089.1 - 1.2 8.6 3.9 25 4.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 OAJ24089.1 - 8.3 6.5 6.5 7.9 6.5 0.1 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain ADH_N PF08240.12 OAJ24091.1 - 2.1e-26 91.9 2.0 5.7e-26 90.5 2.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ24091.1 - 1.9e-22 79.7 0.2 3.2e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQQ PF01011.21 OAJ24091.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat AlaDh_PNT_C PF01262.21 OAJ24091.1 - 0.0078 15.5 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 OAJ24091.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase RVT_3 PF13456.6 OAJ24092.1 - 0.00034 20.4 0.2 0.00054 19.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Spt5_N PF11942.8 OAJ24094.1 - 0.66 11.0 3.0 1.2 10.1 3.0 1.7 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Caskin1-CID PF16600.5 OAJ24094.1 - 3.3 8.4 7.2 2.7 8.6 5.8 1.6 1 1 0 1 1 1 0 Caskin1 CASK-interaction domain SRP-alpha_N PF04086.13 OAJ24094.1 - 3.4 7.5 5.7 4.1 7.2 5.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Helicase_C PF00271.31 OAJ24095.1 - 2.8e-05 24.4 0.0 5.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ24095.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2 PF00096.26 OAJ24095.1 - 0.05 14.1 3.6 0.035 14.6 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 OAJ24095.1 - 5.5 6.5 7.3 21 4.7 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAJ24095.1 - 5.8 7.1 11.4 0.68 10.1 1.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Thi4 PF01946.17 OAJ24097.1 - 5.4e-54 182.9 0.0 7.1e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family TPR_2 PF07719.17 OAJ24098.1 - 2e-10 39.9 19.3 0.21 11.8 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ24098.1 - 1.5e-08 34.1 9.6 0.33 10.9 0.4 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ24098.1 - 3.8e-08 33.5 22.2 0.015 15.6 1.9 7.8 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ24098.1 - 1e-07 32.2 29.7 0.35 11.8 0.5 10.8 10 1 2 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ24098.1 - 3e-06 27.8 24.5 0.018 15.7 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ24098.1 - 9.9e-06 25.2 11.1 4.5 7.5 0.4 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat BTAD PF03704.17 OAJ24098.1 - 2.5e-05 24.7 10.4 0.0058 17.1 0.8 3.6 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_19 PF14559.6 OAJ24098.1 - 2.8e-05 24.6 18.6 0.00015 22.2 1.1 6.0 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ24098.1 - 0.00016 22.1 18.0 0.8 10.5 0.3 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ24098.1 - 0.0005 20.2 15.0 0.22 11.7 2.6 6.6 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ24098.1 - 0.0022 18.1 6.5 0.51 10.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ24098.1 - 0.0099 16.2 0.2 5.7 7.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ24098.1 - 0.01 16.0 0.4 0.01 16.0 0.4 5.1 5 2 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAJ24098.1 - 0.05 14.3 9.7 0.93 10.3 0.1 5.8 6 0 0 6 6 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAJ24098.1 - 0.051 13.2 0.9 1.4 8.6 0.2 2.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 OAJ24098.1 - 0.067 13.1 14.3 5 7.1 0.7 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ24098.1 - 0.097 13.0 8.0 1.1 9.7 0.2 5.3 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ24098.1 - 0.6 9.8 6.6 6.9 6.4 0.2 4.4 5 0 0 5 5 5 0 TPR repeat MMM1 PF10296.9 OAJ24099.1 - 3.8e-09 36.0 1.3 0.0017 17.4 0.0 3.6 3 1 0 4 4 4 3 Maintenance of mitochondrial morphology protein 1 DUF4366 PF14283.6 OAJ24099.1 - 0.0081 16.2 0.0 0.053 13.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF2052 PF09747.9 OAJ24099.1 - 0.1 12.8 12.2 1.2 9.2 7.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 OAJ24099.1 - 0.32 10.6 7.2 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 FAM176 family BSP_II PF05432.11 OAJ24099.1 - 1.4 8.5 9.7 3.7 7.2 0.6 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 OAJ24099.1 - 1.8 6.7 7.6 0.29 9.4 0.5 2.0 2 0 0 2 2 2 0 CDC45-like protein Glypican PF01153.19 OAJ24101.1 - 0.12 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Glypican DPBB_1 PF03330.18 OAJ24104.1 - 0.034 14.4 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Barwin PF00967.17 OAJ24104.1 - 0.04 13.8 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Barwin family GN3L_Grn1 PF08701.11 OAJ24109.1 - 7.6e-25 86.8 17.3 7.6e-25 86.8 17.3 2.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MRP-S25 PF13741.6 OAJ24110.1 - 2.3e-48 164.8 0.1 2.9e-47 161.1 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAJ24110.1 - 2.1e-06 28.0 0.3 0.009 16.3 0.0 2.5 1 1 0 2 2 2 2 Mitochondrial ribosomal protein S23 STG PF15809.5 OAJ24110.1 - 0.022 14.8 1.0 0.04 14.0 1.0 1.3 1 0 0 1 1 1 0 Simian taste bud-specific gene product family SR-25 PF10500.9 OAJ24110.1 - 0.33 10.6 8.5 0.58 9.7 8.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cullin_binding PF03556.15 OAJ24114.1 - 4.1e-32 111.1 0.0 8.1e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 OAJ24114.1 - 2.3e-07 30.5 0.1 4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Herpes_UL21 PF03252.13 OAJ24114.1 - 0.054 12.2 0.3 0.09 11.5 0.1 1.4 2 0 0 2 2 2 0 Herpesvirus UL21 Abhydrolase_6 PF12697.7 OAJ24116.1 - 2.1e-05 25.2 3.8 2.1e-05 25.2 3.8 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family TBK1_ULD PF18396.1 OAJ24116.1 - 0.0028 17.6 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain zf-CCHC PF00098.23 OAJ24117.1 - 1.7e-31 106.9 53.3 8.6e-08 31.9 1.0 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ24117.1 - 3e-07 30.0 37.7 0.016 15.0 0.5 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ24117.1 - 5.7e-07 29.4 33.9 0.0094 15.9 0.3 6.1 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ24117.1 - 4.1e-06 26.4 35.0 0.042 13.6 1.3 6.1 5 1 1 6 6 6 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OAJ24117.1 - 0.077 12.8 52.9 0.25 11.2 4.4 6.4 6 0 0 6 6 6 0 Zinc knuckle Mu-like_Com PF10122.9 OAJ24117.1 - 0.16 11.5 0.1 0.16 11.5 0.1 5.0 5 1 0 5 5 5 0 Mu-like prophage protein Com zf-C2H2 PF00096.26 OAJ24118.1 - 0.00035 20.9 9.1 0.031 14.7 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ24118.1 - 0.0012 19.2 10.3 0.0029 18.0 1.7 2.8 2 0 0 2 2 2 2 Zinc-finger double domain GTP_EFTU PF00009.27 OAJ24119.1 - 3.4e-49 167.0 0.0 5.7e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAJ24119.1 - 3.9e-21 74.9 0.3 6.6e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Elongation Factor G, domain II EFG_C PF00679.24 OAJ24119.1 - 7.9e-16 57.9 0.2 4.7e-08 33.0 0.0 2.5 1 1 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ24119.1 - 1.9e-08 34.6 0.0 5.4e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAJ24119.1 - 0.00065 19.5 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OAJ24119.1 - 0.016 15.3 0.4 0.056 13.5 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase EFG_IV PF03764.18 OAJ24119.1 - 0.023 14.5 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G, domain IV AvrPtoB_bdg PF16847.5 OAJ24119.1 - 0.026 15.0 0.0 0.077 13.5 0.0 1.8 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain OGG_N PF07934.12 OAJ24120.1 - 2.3e-22 79.3 0.0 8e-22 77.6 0.0 1.9 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain NmrA PF05368.13 OAJ24120.1 - 1.8e-11 44.1 0.1 0.0005 19.7 0.0 3.3 3 0 0 3 3 3 3 NmrA-like family HhH-GPD PF00730.25 OAJ24120.1 - 9e-11 42.2 0.0 1.8e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ24120.1 - 0.00058 19.6 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif NAD_binding_10 PF13460.6 OAJ24120.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Aim19 PF10315.9 OAJ24121.1 - 2.1e-18 66.7 7.8 2.7e-17 63.1 7.8 2.6 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 HSP90 PF00183.18 OAJ24127.1 - 1e-75 255.6 16.7 1.2e-75 255.4 16.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAJ24127.1 - 1.6e-15 57.6 0.0 3.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ24127.1 - 4.4e-10 39.5 0.1 4.4e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF45 PF01863.17 OAJ24127.1 - 0.44 10.6 5.3 0.91 9.5 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 YIF1 PF03878.15 OAJ24128.1 - 3.5e-90 301.7 0.0 4.5e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OAJ24128.1 - 0.84 9.3 17.6 0.034 13.9 8.2 2.3 1 1 1 2 2 2 0 Yip1 domain Ribosomal_L11_N PF03946.14 OAJ24128.1 - 5 7.0 7.5 0.2 11.5 1.3 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain SUV3_C PF12513.8 OAJ24129.1 - 2.4e-15 56.2 0.4 5.2e-15 55.1 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 OAJ24129.1 - 8.6e-11 42.2 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRN3 PF05327.11 OAJ24129.1 - 0.47 8.9 3.2 0.87 8.0 3.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNase_PH PF01138.21 OAJ24130.1 - 3e-33 115.1 0.1 4.5e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ24130.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MCM PF00493.23 OAJ24131.1 - 4.5e-97 323.5 0.0 6.2e-97 323.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ24131.1 - 1.5e-38 131.5 0.6 2.7e-38 130.6 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ24131.1 - 3e-27 94.9 1.5 3e-27 94.9 1.5 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ24131.1 - 8.6e-17 61.6 0.0 3.1e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 OAJ24131.1 - 3.8e-08 33.4 0.0 1e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ24131.1 - 4.5e-07 29.5 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ24131.1 - 9.5e-05 22.3 0.0 0.0018 18.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ24131.1 - 0.0098 15.6 0.0 0.59 9.8 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 OAJ24131.1 - 0.0099 16.3 0.1 0.07 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF3256 PF11644.8 OAJ24131.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) DUF3552 PF12072.8 OAJ24131.1 - 0.23 10.8 1.4 0.39 10.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ldh_1_N PF00056.23 OAJ24132.1 - 0.0021 18.2 0.1 0.0029 17.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PIF1 PF05970.14 OAJ24133.1 - 4.7e-47 160.9 0.0 8.2e-47 160.1 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ24133.1 - 1.2e-27 97.4 0.0 2.7e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ24133.1 - 2.7e-07 30.5 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ24133.1 - 1.4e-05 25.4 0.1 4.5e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 OAJ24133.1 - 0.026 13.4 0.1 0.23 10.3 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 OAJ24133.1 - 0.038 14.4 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 OAJ24133.1 - 0.06 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ24133.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 OAJ24133.1 - 0.71 9.6 4.7 2 8.1 0.3 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Med12 PF09497.10 OAJ24134.1 - 2.3e-25 88.6 0.0 8.5e-25 86.8 0.0 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 HMG_CoA_synt_N PF01154.17 OAJ24135.1 - 1.3e-83 279.1 0.3 2.4e-83 278.3 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 OAJ24135.1 - 1.2e-82 277.7 0.0 1.6e-82 277.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Med14 PF08638.11 OAJ24136.1 - 2.3e-44 151.1 0.0 4.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 TAtT PF16811.5 OAJ24136.1 - 0.099 11.9 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 TRAP transporter T-component ARPC4 PF05856.12 OAJ24137.1 - 4.3e-80 267.2 3.9 4.8e-80 267.0 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) CBP4 PF07960.11 OAJ24138.1 - 1.1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 OAJ24138.1 - 0.00042 20.2 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CsbD PF05532.12 OAJ24139.1 - 7.7e-05 22.5 20.6 0.0088 15.9 6.3 3.1 1 1 1 2 2 2 2 CsbD-like RIX1 PF08167.12 OAJ24141.1 - 1.7e-09 37.7 2.0 6.5e-08 32.5 0.2 2.9 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis DUF3025 PF11227.8 OAJ24141.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) RAP1 PF07218.11 OAJ24142.1 - 4.2 5.5 4.1 5.7 5.1 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAP PF00956.18 OAJ24143.1 - 2.3e-95 318.8 4.9 2.3e-95 318.8 4.9 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 OAJ24143.1 - 5.5 7.3 20.7 3.2 8.0 1.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Drc1-Sld2 PF11719.8 OAJ24143.1 - 7.9 5.9 15.2 0.041 13.4 3.7 2.1 1 1 0 2 2 2 0 DNA replication and checkpoint protein Kelch_4 PF13418.6 OAJ24144.1 - 2.9e-23 81.6 0.6 6.8e-07 29.2 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ24144.1 - 5.4e-19 68.0 2.7 0.00054 20.2 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ24144.1 - 3.8e-12 45.6 0.1 1.1e-05 24.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OAJ24144.1 - 1.9e-10 40.6 0.3 0.017 15.4 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 OAJ24144.1 - 3.6e-10 39.6 0.1 0.073 13.1 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OAJ24144.1 - 5.5e-05 23.0 1.0 0.24 11.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif PQQ_3 PF13570.6 OAJ24144.1 - 0.025 15.0 0.1 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain G-alpha PF00503.20 OAJ24145.1 - 4.7e-103 345.1 0.1 5.3e-103 344.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ24145.1 - 2.4e-12 46.7 0.1 2.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 OAJ24145.1 - 0.019 14.3 0.1 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 OAJ24145.1 - 0.024 14.9 0.0 2.8 8.2 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ24145.1 - 0.041 13.6 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OAJ24145.1 - 0.042 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OAJ24145.1 - 0.05 12.9 0.1 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CPT PF07931.12 OAJ24145.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.23 OAJ24145.1 - 0.1 12.7 0.0 17 5.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase MCM PF00493.23 OAJ24145.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Rad1 PF02144.16 OAJ24146.1 - 1.3e-67 227.8 0.0 1.8e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OAJ24146.1 - 0.043 13.3 0.1 4.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Rad9 DUF2834 PF11196.8 OAJ24147.1 - 0.26 11.7 8.9 3.8 7.9 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) MDD_C PF18376.1 OAJ24148.1 - 5.9e-69 231.6 0.0 7.7e-69 231.2 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAJ24148.1 - 5.7e-06 26.5 3.5 8.1e-06 26.0 1.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain DNA_pol_B_palm PF14792.6 OAJ24151.1 - 5.3e-20 71.7 0.1 3.5e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 OAJ24151.1 - 2.4e-19 69.3 0.0 7.8e-19 67.6 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OAJ24151.1 - 1.9e-08 34.0 0.1 1.2e-07 31.4 0.0 2.4 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAJ24151.1 - 4.2e-06 27.0 0.1 9e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAJ24151.1 - 4e-05 23.9 0.0 0.0046 17.3 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 OAJ24151.1 - 0.00048 20.7 0.0 0.058 14.0 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain LIG3_BRCT PF16759.5 OAJ24151.1 - 0.33 11.3 1.3 11 6.4 0.0 3.0 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain XPG_N PF00752.17 OAJ24152.1 - 4e-25 88.2 0.0 9.6e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ24152.1 - 2.1e-24 85.7 0.0 4.8e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OAJ24152.1 - 0.00081 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAJ24152.1 - 0.058 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_14 PF13428.6 OAJ24152.1 - 0.19 12.6 1.5 0.66 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Hemerythrin PF01814.23 OAJ24153.1 - 4.8e-07 30.5 7.9 4.8e-07 30.5 7.9 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF2031 PF09592.10 OAJ24153.1 - 0.52 9.8 3.5 0.19 11.2 0.7 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2031) NAD_binding_2 PF03446.15 OAJ24154.1 - 6.1e-23 81.7 0.2 9.6e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAJ24154.1 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAJ24154.1 - 8.1e-08 32.4 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAJ24154.1 - 3e-05 24.5 0.1 0.00049 20.6 0.0 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UvrC_HhH_N PF08459.11 OAJ24154.1 - 0.031 14.2 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal JmjC PF02373.22 OAJ24156.1 - 1.1e-12 48.4 0.0 2.8e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OAJ24156.1 - 8.7e-10 38.7 0.0 4.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Cupin-like domain F-box-like PF12937.7 OAJ24156.1 - 0.0013 18.6 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 OAJ24156.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein CTP_synth_N PF06418.14 OAJ24157.1 - 8.5e-120 399.0 0.0 1.1e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAJ24157.1 - 1.4e-47 161.9 0.0 2.7e-37 128.4 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.23 OAJ24157.1 - 0.081 13.0 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Acetate_kinase PF00871.17 OAJ24158.1 - 6.2e-07 28.5 0.0 0.0051 15.5 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family Acetate_kinase PF00871.17 OAJ24160.1 - 3.7e-57 193.8 0.0 8e-43 146.6 0.0 2.1 1 1 0 2 2 2 2 Acetokinase family AAA PF00004.29 OAJ24163.1 - 3.6e-32 111.6 0.0 7.3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ24163.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ24163.1 - 7.7e-05 23.1 0.0 0.00057 20.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAJ24163.1 - 0.00014 21.9 0.2 0.0019 18.2 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ24163.1 - 0.0099 16.2 0.1 0.44 10.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ24163.1 - 0.027 14.2 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 OAJ24163.1 - 0.035 14.2 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAJ24163.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ24163.1 - 0.074 12.6 0.3 0.28 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain OrfB_Zn_ribbon PF07282.11 OAJ24163.1 - 0.12 12.3 0.2 0.5 10.3 0.1 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Radial_spoke PF04712.12 OAJ24163.1 - 0.17 10.8 2.4 0.28 10.1 2.4 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein CN_hydrolase PF00795.22 OAJ24164.1 - 2.7e-53 181.0 0.0 3.2e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.22 OAJ24165.1 - 7.4e-30 102.6 0.1 9.5e-18 63.8 0.2 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAJ24165.1 - 6.4e-13 48.7 1.3 7e-05 22.9 0.1 3.1 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain YfdX PF10938.8 OAJ24165.1 - 0.0083 16.1 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 YfdX protein Nup35_RRM PF05172.13 OAJ24165.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ndc80_HEC PF03801.13 OAJ24167.1 - 9.7e-36 122.7 0.0 1.2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 HEC/Ndc80p family LSM PF01423.22 OAJ24168.1 - 2e-18 65.8 0.8 2.5e-18 65.5 0.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ24168.1 - 0.028 14.6 0.2 0.034 14.3 0.2 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 OAJ24168.1 - 0.09 12.7 0.9 0.15 12.0 0.9 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF4826 PF16108.5 OAJ24168.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) SRP9-21 PF05486.12 OAJ24169.1 - 2.1e-10 40.9 1.0 3.4e-08 33.8 1.0 2.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Med3 PF11593.8 OAJ24169.1 - 0.77 8.9 3.2 0.77 8.9 3.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Exo_endo_phos PF03372.23 OAJ24170.1 - 2.9e-12 46.6 0.1 5.7e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MtrG PF04210.13 OAJ24172.1 - 0.071 13.0 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G UBX PF00789.20 OAJ24173.1 - 5.4e-11 42.5 0.0 8.3e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain Auxin_repressed PF05564.12 OAJ24173.1 - 7.9 7.2 10.0 3.5 8.3 3.4 2.7 3 0 0 3 3 3 0 Dormancy/auxin associated protein HIT PF01230.23 OAJ24174.1 - 3.2e-23 82.3 0.0 4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ24174.1 - 1.3e-05 25.7 0.0 1.8e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glycos_transf_3 PF00591.21 OAJ24175.1 - 1.1e-67 228.3 0.0 1.3e-63 215.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAJ24175.1 - 0.0011 18.7 0.5 0.0011 18.7 0.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DUF5401 PF17380.2 OAJ24175.1 - 9.8 4.1 11.0 13 3.7 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Methyltransf_23 PF13489.6 OAJ24176.1 - 1.7e-08 34.5 0.0 3.8e-08 33.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ24176.1 - 1.8e-08 35.0 0.0 5.7e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ24176.1 - 4.1e-08 33.8 0.0 1.6e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ24176.1 - 3.9e-06 27.5 0.0 2.4e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ24176.1 - 1.1e-05 25.2 0.0 3.4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ24176.1 - 0.00012 21.5 0.0 0.00029 20.2 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 OAJ24176.1 - 0.068 12.8 0.2 0.16 11.6 0.1 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 OAJ24176.1 - 0.078 12.3 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAJ24176.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAJ24176.1 - 0.13 11.8 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain MFS_1 PF07690.16 OAJ24180.1 - 4.3e-22 78.5 45.4 4.2e-12 45.7 29.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ24180.1 - 4.2 5.5 10.5 14 3.8 5.3 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Rep_fac-A_3 PF08661.11 OAJ24181.1 - 2.2e-26 92.2 0.2 2.4e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 PIF3 PF05006.12 OAJ24181.1 - 0.058 13.5 0.0 0.069 13.2 0.0 1.0 1 0 0 1 1 1 0 Per os infectivity factor 3 DEAD PF00270.29 OAJ24183.1 - 1.1e-15 57.8 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ24183.1 - 9.4e-06 25.9 0.0 3.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ24183.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RFX_DNA_binding PF02257.15 OAJ24184.1 - 1.2e-18 67.5 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain POT1PC PF16686.5 OAJ24185.1 - 8.6e-16 58.2 0.1 5.7e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAJ24185.1 - 2.3e-10 40.5 0.0 4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 OAJ24185.1 - 0.034 14.1 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Replication protein A OB domain DZR PF12773.7 OAJ24185.1 - 0.074 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OAJ24185.1 - 0.62 9.9 2.9 1.2 9.0 2.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Cyto_heme_lyase PF01265.17 OAJ24186.1 - 1.2e-41 143.2 1.6 5.1e-39 134.6 0.2 2.3 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase PX PF00787.24 OAJ24187.1 - 4.8e-22 78.1 0.5 1.2e-21 76.8 0.5 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAJ24187.1 - 6.2e-05 22.7 4.5 0.078 12.5 0.1 3.4 4 0 0 4 4 4 2 Vps5 C terminal like ANAPC2 PF08672.11 OAJ24187.1 - 0.051 14.1 1.0 5.9 7.5 0.1 3.1 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Peptidase_M75 PF09375.10 OAJ24187.1 - 0.36 10.2 1.9 0.4 10.1 0.1 1.8 2 0 0 2 2 2 0 Imelysin RVT_1 PF00078.27 OAJ24192.1 - 7.3e-15 55.1 0.0 9.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RBR PF17208.3 OAJ24193.1 - 0.00083 20.0 1.4 0.0022 18.7 0.1 2.3 2 0 0 2 2 2 1 RNA binding Region PS-DH PF14765.6 OAJ24193.1 - 0.049 12.9 0.1 0.08 12.2 0.1 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Homeodomain PF00046.29 OAJ24194.1 - 7.6e-19 67.3 1.6 1.1e-18 66.7 1.6 1.3 1 0 0 1 1 1 1 Homeodomain CD34_antigen PF06365.12 OAJ24194.1 - 1.3 8.5 3.1 2 7.9 3.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family API5 PF05918.11 OAJ24194.1 - 1.8 7.3 9.7 2.6 6.8 9.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DRIM PF07539.12 OAJ24195.1 - 3.2e-159 531.2 4.5 3.2e-159 531.2 4.5 3.4 4 1 0 4 4 4 1 Down-regulated in metastasis ParcG PF10274.9 OAJ24195.1 - 0.041 14.0 0.5 0.88 9.7 0.1 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Condensin2nSMC PF12422.8 OAJ24195.1 - 0.099 12.8 0.4 0.58 10.3 0.4 2.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Telomere_reg-2 PF10193.9 OAJ24195.1 - 0.54 10.7 3.0 0.94 9.9 0.2 3.1 3 0 0 3 3 3 0 Telomere length regulation protein Nop14 PF04147.12 OAJ24195.1 - 5 5.2 25.2 1.8 6.7 13.4 2.4 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 OAJ24195.1 - 9.8 4.3 24.5 5.9 5.0 14.2 2.5 2 0 0 2 2 2 0 CDC45-like protein G-alpha PF00503.20 OAJ24196.1 - 1e-113 380.1 0.0 1.2e-113 380.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ24196.1 - 1.3e-14 54.1 0.1 7.3e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ24196.1 - 2.2e-05 24.0 0.1 0.085 12.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ24196.1 - 0.0033 17.7 0.1 0.54 10.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ24196.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvdE PF03851.14 OAJ24197.1 - 5.7e-91 304.6 0.0 8.1e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE CRISPR_Cse1 PF09481.10 OAJ24198.1 - 0.047 12.8 0.1 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) PAP2_3 PF14378.6 OAJ24202.1 - 4.3e-21 75.5 14.5 4.3e-21 75.5 14.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 OAJ24202.1 - 6.6e-08 32.4 5.5 2.1e-07 30.8 5.5 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OAJ24202.1 - 1.4 9.5 7.0 0.83 10.2 3.7 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Ribosomal_L37ae PF01780.19 OAJ24203.1 - 1.5e-40 137.2 8.8 1.6e-40 137.0 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 OAJ24203.1 - 0.0013 18.8 1.2 0.0019 18.3 1.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 OAJ24203.1 - 0.002 18.0 2.1 0.0033 17.4 2.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 OAJ24203.1 - 0.017 15.1 5.4 0.45 10.6 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 OAJ24203.1 - 0.078 13.4 7.6 0.34 11.4 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.11 OAJ24203.1 - 0.12 12.0 1.2 1 9.0 0.0 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF2175 PF09943.9 OAJ24203.1 - 0.12 12.7 2.1 3.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) C1_2 PF03107.16 OAJ24203.1 - 0.54 10.6 3.7 1.6 9.1 3.8 1.7 1 1 0 1 1 1 0 C1 domain Zn_ribbon_SprT PF17283.2 OAJ24203.1 - 4.3 7.3 7.5 0.95 9.4 3.1 2.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Sec8_exocyst PF04048.14 OAJ24204.1 - 1.7e-34 118.7 0.3 4.7e-34 117.3 0.3 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 OAJ24204.1 - 4.5e-05 23.6 0.5 0.00052 20.1 0.1 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 OAJ24204.1 - 0.00069 19.0 0.8 0.0016 17.8 0.8 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 OAJ24204.1 - 0.0076 14.9 0.9 0.014 14.0 0.9 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 NAD_binding_10 PF13460.6 OAJ24204.1 - 0.039 13.8 4.4 0.33 10.8 0.1 3.6 4 0 0 4 4 4 0 NAD(P)H-binding Metal_resist PF13801.6 OAJ24205.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance GCH_III PF05165.12 OAJ24205.1 - 0.26 10.5 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase III PhoLip_ATPase_C PF16212.5 OAJ24206.1 - 5.3e-75 252.4 22.7 1.1e-74 251.3 22.7 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ24206.1 - 1.6e-27 95.0 2.9 3.7e-27 93.8 2.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAJ24206.1 - 9.1e-12 44.9 0.0 4.1e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ24206.1 - 3.1e-11 44.0 1.6 2.2e-06 28.1 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ24206.1 - 1.7e-05 24.5 0.0 0.00015 21.4 0.0 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ24206.1 - 0.0033 17.2 0.1 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 2TM PF13239.6 OAJ24206.1 - 6.6 7.1 11.0 5.1 7.5 3.8 3.4 3 0 0 3 3 3 0 2TM domain eIF2A PF08662.11 OAJ24207.1 - 7.8e-82 273.9 0.2 2.1e-79 265.9 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAJ24207.1 - 7.5e-06 26.6 0.7 0.66 10.9 0.2 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Proteasome_A_N PF10584.9 OAJ24207.1 - 0.047 13.4 0.8 14 5.4 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDV3 PF15359.6 OAJ24207.1 - 0.43 11.1 4.0 2.2 8.8 1.0 2.6 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 IATP PF04568.12 OAJ24207.1 - 0.63 10.5 4.8 0.58 10.6 0.4 2.6 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP EBP PF05241.12 OAJ24208.1 - 0.32 10.4 8.0 0.87 9.0 8.0 1.6 1 1 0 1 1 1 0 Emopamil binding protein Pkinase PF00069.25 OAJ24209.1 - 1.9e-63 214.3 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24209.1 - 1.1e-19 70.7 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ24209.1 - 4.8e-07 29.9 0.6 2.6e-05 24.3 0.3 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ24209.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ24209.1 - 0.018 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OAJ24209.1 - 0.019 14.6 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 OAJ24209.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HTH_Tnp_1 PF01527.20 OAJ24210.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.6 OAJ24210.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Nup54 PF13874.6 OAJ24211.1 - 1.2e-24 87.0 3.7 4.6e-23 81.9 0.0 2.8 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 OAJ24211.1 - 0.0064 16.4 0.2 0.0064 16.4 0.2 2.3 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain Nucleoporin_FG PF13634.6 OAJ24211.1 - 0.029 15.2 63.6 0.36 11.7 26.6 3.9 2 1 1 3 3 3 0 Nucleoporin FG repeat region Spt20 PF12090.8 OAJ24211.1 - 5.5 6.5 14.4 9.3 5.8 14.4 1.3 1 0 0 1 1 1 0 Spt20 family DUF1748 PF08520.10 OAJ24212.1 - 5.7e-21 74.2 0.0 6.7e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MmgE_PrpD PF03972.14 OAJ24213.1 - 9.4e-144 479.2 0.5 1.4e-143 478.6 0.5 1.2 1 0 0 1 1 1 1 MmgE/PrpD family 5_3_exonuc PF01367.20 OAJ24213.1 - 0.12 12.9 0.1 1.8 9.3 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold VPS13_mid_rpt PF16910.5 OAJ24215.1 - 6.1e-94 313.8 9.7 8.4e-92 306.8 2.8 4.8 4 0 0 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 OAJ24215.1 - 9.6e-83 277.7 0.0 6.1e-79 265.2 0.0 4.1 4 0 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OAJ24215.1 - 2.2e-82 276.4 2.9 3.4e-79 266.0 0.1 3.6 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAJ24215.1 - 1.1e-75 253.3 3.5 6.2e-70 234.6 0.1 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAJ24215.1 - 7e-40 135.8 0.1 5.7e-39 132.8 0.0 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAJ24215.1 - 1.5e-09 38.0 0.2 3.1e-08 33.8 0.0 2.9 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Serinc PF03348.15 OAJ24216.1 - 0.0049 15.8 0.1 0.0062 15.5 0.1 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) RNB PF00773.19 OAJ24218.1 - 1.1e-92 310.8 0.0 1.5e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 OAJ24218.1 - 4.4e-24 84.9 0.0 9e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAJ24218.1 - 1.6e-20 72.9 0.1 3e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 OAJ24218.1 - 9.2e-19 67.3 0.0 2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OAJ24218.1 - 5.9e-08 32.8 0.0 2.6e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 OAJ24218.1 - 1e-07 32.3 0.0 4.1e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 PIN domain Apolipoprotein PF01442.18 OAJ24225.1 - 0.014 15.3 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Helitron_like_N PF14214.6 OAJ24226.1 - 7.6e-21 75.2 0.0 1.2e-20 74.5 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cellulase PF00150.18 OAJ24229.1 - 0.00048 19.6 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4604 PF15377.6 OAJ24231.1 - 2.5e-19 70.4 22.6 2.9e-19 70.1 22.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF572 PF04502.13 OAJ24231.1 - 1.3 8.6 16.0 1.6 8.2 16.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.13 OAJ24231.1 - 7.1 6.5 21.3 9.4 6.1 21.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Herpes_DNAp_acc PF04929.12 OAJ24231.1 - 9.6 5.1 10.9 1.1 8.1 6.4 1.6 2 0 0 2 2 2 0 Herpes DNA replication accessory factor ATP-synt_ab PF00006.25 OAJ24232.1 - 1.8e-67 227.1 0.0 2.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAJ24232.1 - 6e-13 49.1 0.2 1e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OAJ24232.1 - 0.056 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) zf-FCS PF06467.14 OAJ24234.1 - 0.048 13.6 3.8 0.1 12.6 3.8 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif EF_assoc_2 PF08356.12 OAJ24235.1 - 8.7e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 EF hand associated DinB_2 PF12867.7 OAJ24235.1 - 0.059 13.9 0.0 1.6 9.2 0.0 2.0 2 0 0 2 2 2 0 DinB superfamily NDC10_II PF16787.5 OAJ24236.1 - 0.001 18.2 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 p450 PF00067.22 OAJ24238.1 - 2.4e-65 221.1 0.0 8.2e-50 169.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1864 PF08933.11 OAJ24238.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) FAD_binding_2 PF00890.24 OAJ24239.1 - 2.1e-08 33.7 0.0 3.2e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain His_Phos_2 PF00328.22 OAJ24240.1 - 5.4e-30 105.0 0.0 6.7e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aminotran_MocR PF12897.7 OAJ24240.1 - 0.058 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DDE_Tnp_4 PF13359.6 OAJ24241.1 - 2.1e-24 86.0 0.0 3.9e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease YrbL-PhoP_reg PF10707.9 OAJ24241.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DDE_Tnp_1 PF01609.21 OAJ24241.1 - 0.058 13.0 4.6 0.11 12.1 0.0 2.9 2 1 0 2 2 2 0 Transposase DDE domain CsbD PF05532.12 OAJ24243.1 - 5.4e-18 64.6 16.5 1.4e-09 37.7 4.9 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 OAJ24243.1 - 0.0026 18.1 1.0 0.005 17.2 0.8 1.6 1 1 0 1 1 1 1 Heat shock protein 9/12 UCH PF00443.29 OAJ24244.1 - 2.9e-56 190.8 0.0 3.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ24244.1 - 4.5e-32 111.9 0.0 6.8e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OAJ24244.1 - 0.00022 20.8 0.9 0.039 13.4 1.3 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase CCDC24 PF15669.5 OAJ24244.1 - 0.27 11.1 1.5 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family adh_short PF00106.25 OAJ24245.1 - 3.5e-13 49.5 0.4 6.1e-11 42.1 0.2 3.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24245.1 - 7e-09 35.6 0.3 2.3e-07 30.6 0.1 2.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAJ24245.1 - 0.00016 21.6 0.2 0.00026 20.9 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ24245.1 - 0.0026 18.3 1.8 0.0077 16.8 0.6 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 OAJ24245.1 - 0.0041 17.0 0.1 0.0067 16.4 0.1 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 OAJ24245.1 - 0.011 15.7 0.1 0.052 13.5 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ApbA PF02558.16 OAJ24245.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAJ24245.1 - 0.13 12.3 0.5 0.95 9.5 0.2 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DEAD PF00270.29 OAJ24246.1 - 2.6e-52 177.1 0.0 2.6e-51 173.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ24246.1 - 7.8e-32 109.9 0.0 4.8e-29 100.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ24246.1 - 6.2e-07 29.6 0.0 5.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ24246.1 - 0.002 18.5 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 OAJ24246.1 - 0.0083 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain Glyco_hydro_65m PF03632.15 OAJ24247.1 - 3.7e-38 131.4 2.3 5.9e-15 55.0 0.1 3.3 1 1 2 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 OAJ24247.1 - 4.6e-27 95.1 0.0 8.4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 OAJ24247.1 - 5.3e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 OAJ24247.1 - 0.0037 17.4 0.0 0.034 14.3 0.0 2.6 2 1 0 2 2 2 1 F5/8 type C domain MobB PF03205.14 OAJ24247.1 - 0.038 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Borrelia_rep PF03183.13 OAJ24247.1 - 8.7 6.6 5.6 0.79 9.8 0.2 2.2 2 0 0 2 2 2 0 Borrelia repeat protein PRKCSH PF07915.13 OAJ24251.1 - 6.7e-11 43.0 0.0 7.6e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein TPR_12 PF13424.6 OAJ24253.1 - 0.015 15.5 0.1 0.047 14.0 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TRIC PF05197.13 OAJ24254.1 - 0.00011 21.8 0.2 0.0013 18.4 0.2 2.2 1 1 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 OAJ24254.1 - 0.055 13.4 9.9 0.2 11.6 1.4 3.5 3 1 0 3 3 3 0 UPF0126 domain ETC_C1_NDUFA4 PF04800.12 OAJ24255.1 - 8.7e-35 118.9 0.1 1.1e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Proteasome PF00227.26 OAJ24256.1 - 6.9e-47 159.4 0.0 8.7e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ24256.1 - 7.9e-14 51.0 0.1 1.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SLAC1 PF03595.17 OAJ24257.1 - 3.4e-63 213.9 45.6 5.6e-63 213.2 45.6 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel adh_short PF00106.25 OAJ24258.1 - 4e-18 65.6 0.3 5.3e-07 29.3 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24258.1 - 4.6e-09 36.2 0.5 2.8e-05 23.8 0.0 2.8 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ24258.1 - 3.4e-06 27.1 0.1 1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 KR domain Complex1_49kDa PF00346.19 OAJ24261.1 - 2e-121 404.2 0.0 2.6e-121 403.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OAJ24261.1 - 0.0061 15.5 0.0 0.011 14.7 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase MAS20 PF02064.15 OAJ24262.1 - 3.1e-27 95.2 3.2 1.5e-26 93.0 3.2 2.2 1 1 0 1 1 1 1 MAS20 protein import receptor Thioredoxin PF00085.20 OAJ24263.1 - 1.3e-25 89.4 0.0 4.9e-21 74.7 0.0 3.0 3 1 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 OAJ24263.1 - 4.2e-06 26.3 0.0 0.00041 19.8 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAJ24263.1 - 1e-05 25.9 0.1 2.8e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OAJ24263.1 - 0.0019 18.4 0.1 0.032 14.4 0.1 2.6 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 OAJ24263.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 OAJ24263.1 - 0.051 13.9 0.1 0.24 11.8 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like COPIIcoated_ERV PF07970.12 OAJ24264.1 - 1.2e-77 260.7 0.0 1.8e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAJ24264.1 - 4.6e-26 91.0 0.1 1.7e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PNP_phzG_C PF10590.9 OAJ24265.1 - 2.8e-20 72.1 3.2 5.3e-20 71.2 3.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 OAJ24265.1 - 6.1e-17 61.6 0.1 8.1e-16 58.0 0.1 2.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNase_H2_suC PF08615.11 OAJ24266.1 - 4.7e-08 33.3 5.2 4.7e-08 33.3 5.2 5.4 3 2 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3123 PF11321.8 OAJ24268.1 - 4.6 7.9 8.2 4.1 8.1 6.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) Holin_BhlA PF10960.8 OAJ24270.1 - 0.23 11.4 0.1 0.55 10.2 0.1 1.6 1 0 0 1 1 1 0 BhlA holin family BUD22 PF09073.10 OAJ24270.1 - 1.6 8.0 4.3 2.3 7.5 4.3 1.1 1 0 0 1 1 1 0 BUD22 DUF3584 PF12128.8 OAJ24273.1 - 0.2 9.1 2.6 0.3 8.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Glyco_tranf_2_3 PF13641.6 OAJ24274.1 - 2.8e-20 73.2 0.0 3.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ24274.1 - 1.1e-16 61.3 4.6 1.1e-16 61.3 4.6 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAJ24274.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ24274.1 - 3.2e-07 30.3 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Gate PF07670.14 OAJ24274.1 - 0.035 14.4 2.7 0.076 13.3 2.7 1.6 1 0 0 1 1 1 0 Nucleoside recognition TPR_12 PF13424.6 OAJ24280.1 - 0.012 15.9 0.7 0.037 14.3 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Tyrosinase PF00264.20 OAJ24281.1 - 6.6e-40 137.8 2.8 8.4e-40 137.4 2.1 1.4 1 1 1 2 2 2 1 Common central domain of tyrosinase DUF1465 PF07323.12 OAJ24283.1 - 0.027 14.3 4.0 0.39 10.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Laminin_II PF06009.12 OAJ24283.1 - 0.027 14.5 1.7 0.038 14.0 0.3 1.8 1 1 1 2 2 2 0 Laminin Domain II TBCA PF02970.16 OAJ24283.1 - 0.027 14.8 0.6 0.04 14.3 0.6 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A Jnk-SapK_ap_N PF09744.9 OAJ24283.1 - 0.056 13.7 1.7 0.14 12.3 1.8 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Cep57_CLD PF14073.6 OAJ24283.1 - 0.057 13.4 1.7 0.069 13.2 1.7 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Seryl_tRNA_N PF02403.22 OAJ24283.1 - 0.1 12.8 3.1 0.27 11.5 3.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TssO PF17561.2 OAJ24283.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssO GreA_GreB_N PF03449.15 OAJ24283.1 - 0.16 12.2 2.7 0.3 11.3 2.4 1.7 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Tyrosinase PF00264.20 OAJ24284.1 - 1.9e-36 126.5 4.3 2.6e-36 126.0 4.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OAJ24285.1 - 1.4e-39 136.7 1.2 1.9e-39 136.2 1.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OAJ24287.1 - 3.6e-36 125.5 1.1 3.6e-36 125.5 1.1 1.7 1 1 1 2 2 2 1 Common central domain of tyrosinase RPEL PF02755.15 OAJ24288.1 - 0.059 13.1 0.0 15 5.4 0.1 2.5 2 0 0 2 2 2 0 RPEL repeat tRNA-synt_2c PF01411.19 OAJ24290.1 - 4.9e-212 705.3 0.0 7.9e-212 704.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAJ24290.1 - 4.6e-17 61.8 0.2 1.1e-16 60.7 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAJ24290.1 - 0.12 12.8 8.9 1.7 9.0 8.7 2.6 1 1 0 1 1 1 0 DHHA1 domain Pkinase PF00069.25 OAJ24291.1 - 9.5e-60 202.2 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24291.1 - 2.6e-38 131.8 0.0 3.4e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ24291.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ24291.1 - 0.0023 17.0 0.0 0.0046 16.0 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ24291.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAJ24291.1 - 0.026 14.4 0.1 0.31 10.9 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family cobW PF02492.19 OAJ24293.1 - 1.9e-43 148.1 4.3 2.1e-42 144.7 4.3 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAJ24293.1 - 7.5e-18 64.3 0.2 2e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAJ24293.1 - 0.017 15.0 0.6 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OAJ24293.1 - 0.029 14.7 0.6 0.46 10.7 0.6 2.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OAJ24293.1 - 0.033 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SDA1 PF05285.12 OAJ24293.1 - 0.033 13.6 3.1 0.077 12.4 3.1 1.5 1 1 0 1 1 1 0 SDA1 MobB PF03205.14 OAJ24293.1 - 0.054 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 OAJ24293.1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 OAJ24293.1 - 0.12 12.4 0.1 0.64 10.1 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 OAJ24293.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 OAJ24293.1 - 0.17 10.2 1.8 0.24 9.7 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ24293.1 - 0.93 9.6 6.3 1.9 8.6 6.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein AAA_16 PF13191.6 OAJ24293.1 - 1.2 9.5 3.0 1 9.7 0.4 2.5 3 1 0 3 3 3 0 AAA ATPase domain RRN3 PF05327.11 OAJ24293.1 - 1.2 7.6 3.9 2.6 6.5 3.9 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ24293.1 - 8.8 4.3 12.9 14 3.6 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cutinase PF01083.22 OAJ24294.1 - 9.2e-23 81.1 0.0 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF726 PF05277.12 OAJ24294.1 - 0.76 8.6 0.0 0.76 8.6 0.0 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF726) Pyr_redox_2 PF07992.14 OAJ24296.1 - 4.1e-37 128.0 0.7 6.7e-37 127.3 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAJ24296.1 - 1.9e-18 66.5 0.0 3.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAJ24296.1 - 2.6e-15 56.7 2.3 9e-14 51.8 0.3 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ24296.1 - 7.4e-15 54.8 0.0 6.6e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 OAJ24296.1 - 8.7e-12 45.2 9.7 5.9e-10 39.3 6.2 3.0 3 0 0 3 3 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 OAJ24296.1 - 9.5e-12 44.7 0.1 5.2e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAJ24296.1 - 6.7e-11 41.9 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 OAJ24296.1 - 9.6e-06 25.4 0.0 0.011 15.7 0.1 2.9 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 OAJ24296.1 - 0.00018 21.5 3.2 0.33 10.9 0.1 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAJ24296.1 - 0.0031 16.7 0.7 1.5 7.8 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ24296.1 - 0.008 15.8 5.2 0.07 12.7 0.2 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ24296.1 - 0.016 15.4 0.4 0.056 13.7 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAJ24296.1 - 0.14 11.2 0.2 6.3 5.8 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 OAJ24296.1 - 0.15 12.3 5.3 3 8.1 0.1 3.6 4 0 0 4 4 4 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAJ24296.1 - 0.22 10.8 0.7 20 4.3 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Retrotrans_gag PF03732.17 OAJ24297.1 - 0.00049 20.3 0.2 0.00089 19.5 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF5476 PF17570.2 OAJ24297.1 - 0.14 12.5 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5476) SPX PF03105.19 OAJ24302.1 - 1.9e-17 64.2 4.7 4.8e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 SPX domain Phage_integrase PF00589.22 OAJ24302.1 - 6.9e-06 26.0 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family FTR1 PF03239.14 OAJ24304.1 - 0.0067 15.6 0.4 0.008 15.4 0.4 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3262 PF11660.8 OAJ24304.1 - 0.012 16.0 2.9 0.025 14.9 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3262) DUF485 PF04341.12 OAJ24304.1 - 0.053 13.5 0.6 0.058 13.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UCR_TM PF02921.14 OAJ24305.1 - 7.7e-12 45.5 3.0 3.8e-11 43.3 3.0 2.2 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 OAJ24305.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Cwf_Cwc_15 PF04889.12 OAJ24306.1 - 0.0041 16.9 9.7 0.0053 16.5 9.7 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SLC12 PF03522.15 OAJ24306.1 - 0.013 14.5 5.6 0.021 13.9 5.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 OAJ24306.1 - 0.12 10.9 9.6 0.12 10.9 9.6 1.1 1 0 0 1 1 1 0 Macoilin family Pox_Ag35 PF03286.14 OAJ24306.1 - 0.23 11.2 12.7 0.41 10.4 12.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Apt1 PF10351.9 OAJ24306.1 - 1.6 7.5 13.1 1.9 7.3 13.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWIRM-assoc_2 PF16496.5 OAJ24306.1 - 1.6 7.5 12.6 2.3 7.0 12.6 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SAPS PF04499.15 OAJ24306.1 - 1.8 7.3 5.4 2 7.1 5.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein P_C PF06640.11 OAJ24306.1 - 2 8.5 18.4 4.3 7.4 18.4 1.5 1 0 0 1 1 1 0 P protein C-terminus Miga PF10265.9 OAJ24306.1 - 2.2 7.1 8.0 3 6.7 8.0 1.2 1 0 0 1 1 1 0 Mitoguardin SURF2 PF05477.11 OAJ24306.1 - 5 6.8 13.9 7.8 6.1 13.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) THEG PF14912.6 OAJ24307.1 - 0.089 13.3 1.2 0.18 12.3 1.2 1.6 1 1 0 1 1 1 0 Testicular haploid expressed repeat E1-E2_ATPase PF00122.20 OAJ24308.1 - 3.2e-40 137.6 3.8 4.5e-38 130.6 0.1 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 OAJ24308.1 - 2.9e-17 63.7 0.3 6.7e-17 62.5 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ24308.1 - 1.2e-12 47.4 0.3 2.8e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ24308.1 - 0.002 17.9 0.1 0.0039 17.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ24308.1 - 0.033 14.3 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Ni_hydr_CYTB PF01292.20 OAJ24308.1 - 0.079 12.5 4.5 0.14 11.8 0.0 2.9 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 PsbI PF02532.14 OAJ24308.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.3 3 0 0 3 3 3 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Pex2_Pex12 PF04757.14 OAJ24309.1 - 9e-42 143.2 0.1 1.2e-41 142.8 0.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OAJ24309.1 - 1.6e-06 27.8 0.5 2.4e-06 27.3 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ24309.1 - 0.00075 19.3 0.6 0.0012 18.6 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ24309.1 - 0.016 15.5 0.3 0.025 14.9 0.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OAJ24309.1 - 0.057 13.5 1.3 0.097 12.7 1.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ24309.1 - 0.28 11.1 0.3 0.42 10.5 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kinesin PF00225.23 OAJ24310.1 - 9.8e-103 343.6 0.0 3.4e-102 341.8 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ24310.1 - 2.8e-24 85.8 0.0 1.2e-23 83.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Apolipoprotein PF01442.18 OAJ24310.1 - 0.0025 17.7 6.8 0.0025 17.7 6.8 4.7 1 1 4 5 5 5 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAJ24310.1 - 0.29 11.1 13.5 1.6 8.8 0.1 4.5 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 OAJ24310.1 - 9.5 4.0 9.4 0.29 9.1 0.8 2.1 2 0 0 2 2 2 0 Prominin PWWP PF00855.17 OAJ24311.1 - 1.5e-05 25.3 0.3 3.1e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 PWWP domain SURF1 PF02104.15 OAJ24312.1 - 8.7e-40 136.8 0.0 1.2e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family VCPO_N PF17897.1 OAJ24312.1 - 0.006 16.4 1.1 0.018 14.9 1.1 1.6 1 1 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain Dynamitin PF04912.14 OAJ24313.1 - 3.4e-53 181.4 0.0 4.6e-38 131.6 0.0 2.2 2 0 0 2 2 2 2 Dynamitin DASH_Dad2 PF08654.10 OAJ24313.1 - 0.35 11.3 1.3 6.6 7.2 0.3 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF2020 PF09449.10 OAJ24313.1 - 0.61 9.9 7.0 0.24 11.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Snf7 PF03357.21 OAJ24314.1 - 8.8e-44 149.1 12.4 8.8e-44 149.1 12.4 2.0 2 0 0 2 2 2 1 Snf7 Misat_Tub_SegII PF10644.9 OAJ24314.1 - 0.02 15.2 0.2 0.044 14.1 0.2 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ribosomal_60s PF00428.19 OAJ24314.1 - 0.095 13.3 2.6 2.4 8.8 0.1 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein TraC PF07820.12 OAJ24314.1 - 0.099 13.0 4.7 2 8.8 0.9 2.4 2 0 0 2 2 2 0 TraC-like protein DUF3138 PF11336.8 OAJ24314.1 - 0.27 9.8 3.4 0.26 9.9 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF5082 PF16888.5 OAJ24314.1 - 0.52 10.6 9.7 0.25 11.6 6.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Sin3_corepress PF08295.12 OAJ24314.1 - 2 8.5 4.8 0.4 10.8 0.4 2.1 3 0 0 3 3 3 0 Sin3 family co-repressor NUDIX PF00293.28 OAJ24315.1 - 9.1e-20 71.0 0.1 6.9e-19 68.2 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 OAJ24315.1 - 0.058 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase zf-rbx1 PF12678.7 OAJ24316.1 - 6.4e-13 48.8 2.8 1.1e-12 48.0 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ24316.1 - 5.5e-10 39.4 7.7 1.5e-09 38.1 7.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ24316.1 - 9.7e-07 28.6 2.5 1.9e-06 27.6 2.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ24316.1 - 1.2e-06 28.5 0.8 2.3e-06 27.6 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAJ24316.1 - 5.4e-06 26.3 3.1 9.6e-06 25.5 3.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ24316.1 - 1.1e-05 25.2 5.4 1.1e-05 25.2 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ24316.1 - 0.00014 21.7 2.9 0.00025 20.9 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ24316.1 - 0.00024 20.9 2.7 0.00043 20.1 2.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAJ24316.1 - 0.0014 18.2 2.3 0.0027 17.3 2.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OAJ24316.1 - 0.0014 18.4 7.2 0.011 15.6 7.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ24316.1 - 0.0029 17.3 2.1 0.0029 17.3 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAJ24316.1 - 0.0078 16.4 3.0 0.013 15.7 2.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAJ24316.1 - 0.043 14.0 0.2 0.096 12.9 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 OAJ24316.1 - 0.48 10.8 3.9 0.84 10.0 3.9 1.3 1 0 0 1 1 1 0 RING-like domain TMEM154 PF15102.6 OAJ24317.1 - 1.8e-06 27.9 0.2 4e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 OAJ24317.1 - 0.0069 15.8 0.4 0.0097 15.3 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) EphA2_TM PF14575.6 OAJ24317.1 - 0.074 13.9 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OAJ24317.1 - 0.085 12.7 2.0 0.29 10.9 2.0 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 MGC-24 PF05283.11 OAJ24317.1 - 0.31 11.5 11.8 0.11 13.0 6.3 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 OAJ24317.1 - 1.1 9.2 26.7 0.077 13.0 20.0 2.2 3 0 0 3 3 3 0 Mucin-like glycoprotein CAP_N PF01213.19 OAJ24318.1 - 2.5e-94 316.4 21.8 2.5e-94 316.4 21.8 4.0 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAJ24318.1 - 1.8e-53 180.4 3.7 2.3e-53 180.0 3.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAJ24318.1 - 0.0038 17.0 1.0 0.0067 16.1 1.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CCDC53 PF10152.9 OAJ24318.1 - 0.2 12.0 0.4 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Metal_resist PF13801.6 OAJ24318.1 - 3.9 7.7 13.6 6 7.1 3.5 2.9 3 0 0 3 3 3 0 Heavy-metal resistance GRA6 PF05084.13 OAJ24320.1 - 0.025 14.5 1.0 0.025 14.5 1.0 1.8 2 1 0 2 2 2 0 Granule antigen protein (GRA6) TMEM154 PF15102.6 OAJ24320.1 - 0.034 14.0 0.7 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Rab_eff_C PF04698.12 OAJ24320.1 - 0.66 8.2 3.4 0.99 7.6 3.4 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Alpha_GJ PF03229.13 OAJ24320.1 - 7.8 7.1 20.7 0.068 13.7 7.8 2.6 2 1 0 2 2 2 0 Alphavirus glycoprotein J Ribosomal_S7 PF00177.21 OAJ24321.1 - 2.5e-36 124.6 1.2 3.2e-36 124.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.32 OAJ24322.1 - 1.7e-36 123.6 11.1 1.8e-06 28.6 0.0 8.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24322.1 - 1.4e-16 60.5 0.1 0.0027 17.9 0.0 5.4 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAJ24322.1 - 2e-05 24.4 0.1 4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 OAJ24322.1 - 0.015 13.9 2.4 1.6 7.3 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ctr PF04145.15 OAJ24323.1 - 2.1e-37 129.0 3.2 5.2e-37 127.7 3.2 1.7 1 1 0 1 1 1 1 Ctr copper transporter family HHV-5_US34A PF17087.5 OAJ24323.1 - 0.15 12.2 0.5 0.15 12.2 0.5 2.2 2 0 0 2 2 2 0 Herpesvirus US34A protein family PE_PPE_C PF12484.8 OAJ24323.1 - 7.8 7.5 10.6 0.5 11.3 0.5 2.7 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal dUTPase PF00692.19 OAJ24324.1 - 8.3e-45 151.6 0.0 1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF2015 PF09435.10 OAJ24328.1 - 1.4e-25 89.3 0.0 2e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ammonium_transp PF00909.21 OAJ24329.1 - 1.3e-105 353.4 25.8 1.5e-105 353.2 25.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sec6 PF06046.13 OAJ24330.1 - 1.4e-146 489.3 0.0 2.3e-146 488.6 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 OAJ24330.1 - 0.00075 18.6 1.5 0.00075 18.6 1.5 2.5 3 0 0 3 3 3 1 Vps53-like, N-terminal Stanniocalcin PF03298.13 OAJ24330.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Stanniocalcin family Ribosomal_60s PF00428.19 OAJ24331.1 - 1.9e-25 89.3 9.1 2.2e-25 89.1 9.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Metallophos_3 PF14582.6 OAJ24331.1 - 0.095 12.0 0.3 0.11 11.8 0.3 1.3 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily RNA_pol_Rpb1_5 PF04998.17 OAJ24332.1 - 1.2e-16 61.0 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 CCDC106 PF15794.5 OAJ24332.1 - 1.3 8.6 7.7 2 8.1 7.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DNA_pol_phi PF04931.13 OAJ24332.1 - 1.6 6.7 14.7 2.1 6.3 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OAJ24332.1 - 8.9 6.0 7.6 19 4.9 7.6 1.6 1 0 0 1 1 1 0 FAM176 family GHMP_kinases_N PF00288.26 OAJ24333.1 - 2.6e-10 40.4 0.3 8.2e-10 38.8 0.2 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ24333.1 - 0.0027 18.0 0.0 0.0087 16.4 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal Thioredoxin PF00085.20 OAJ24334.1 - 3.8e-23 81.4 0.0 2.3e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ24334.1 - 6.8e-05 23.3 0.0 0.00029 21.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ24334.1 - 0.012 15.6 0.2 0.031 14.2 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 OAJ24334.1 - 0.013 14.9 0.1 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAJ24334.1 - 0.019 15.3 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ24334.1 - 0.093 12.9 0.0 0.093 12.9 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like Aha1_N PF09229.11 OAJ24336.1 - 2.4e-29 102.3 0.0 3.7e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAJ24336.1 - 8.2e-17 61.6 0.0 1.6e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Sporozoite_P67 PF05642.11 OAJ24336.1 - 0.27 9.3 8.4 0.34 8.9 8.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MAGE_N PF12440.8 OAJ24336.1 - 0.49 11.1 13.9 1.3 9.7 13.9 1.8 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal VHS PF00790.19 OAJ24337.1 - 2.5e-32 111.6 0.0 5.5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 OAJ24337.1 - 6.4e-15 54.5 0.1 1.1e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ24337.1 - 1e-13 50.9 0.3 1.8e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ24337.1 - 1.4e-10 40.7 0.2 2.4e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAJ24337.1 - 8.3e-08 32.4 1.5 1.4e-07 31.8 0.3 2.0 2 0 0 2 2 2 1 GAT domain HEPN_AbiU2 PF18734.1 OAJ24337.1 - 0.001 18.6 0.9 0.0021 17.6 0.9 1.5 1 0 0 1 1 1 1 AbiU2 Hrs_helical PF12210.8 OAJ24337.1 - 0.017 15.7 0.2 0.057 14.0 0.2 1.9 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Med26 PF08711.11 OAJ24337.1 - 0.16 12.1 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain TTSSLRR PF12468.8 OAJ24337.1 - 0.47 10.7 4.2 1.8 8.9 4.2 2.0 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DUF775 PF05603.12 OAJ24338.1 - 5e-44 150.2 0.0 5.7e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF2237 PF09996.9 OAJ24339.1 - 1.2e-38 131.6 0.0 1.5e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) HEAT_EZ PF13513.6 OAJ24340.1 - 5.2e-24 84.3 6.6 3.7e-06 27.3 0.0 8.9 9 0 0 9 9 9 6 HEAT-like repeat HEAT PF02985.22 OAJ24340.1 - 9.3e-19 65.9 9.4 0.00022 21.2 0.1 8.8 8 0 0 8 8 7 5 HEAT repeat HEAT_2 PF13646.6 OAJ24340.1 - 1.4e-17 63.9 10.2 0.017 15.5 0.0 8.3 4 3 3 8 8 7 6 HEAT repeats UME PF08064.13 OAJ24340.1 - 1.8e-08 34.2 0.0 0.079 12.9 0.0 5.3 4 1 1 5 5 5 2 UME (NUC010) domain MMS19_C PF12460.8 OAJ24340.1 - 2.2e-07 30.3 0.3 0.0028 16.8 0.0 4.9 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OAJ24340.1 - 4.4e-07 29.7 1.6 1e-06 28.6 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 OAJ24340.1 - 6.2e-07 29.6 0.0 0.012 15.7 0.0 4.1 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CAS_CSE1 PF03378.15 OAJ24340.1 - 1.3e-05 24.0 1.3 0.0039 15.7 0.0 3.7 5 0 0 5 5 5 1 CAS/CSE protein, C-terminus Vac14_Fab1_bd PF12755.7 OAJ24340.1 - 2.8e-05 24.6 0.0 0.47 11.1 0.0 4.9 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAJ24340.1 - 4.2e-05 22.3 0.2 0.31 9.5 0.0 4.0 4 0 0 4 4 4 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 OAJ24340.1 - 5.9e-05 23.3 0.1 0.84 10.0 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 OAJ24340.1 - 6.5e-05 22.6 0.0 2.3 7.7 0.0 4.9 4 1 1 5 5 5 2 CLASP N terminal DUF3385 PF11865.8 OAJ24340.1 - 0.00016 21.6 0.5 38 4.2 0.0 6.3 8 0 0 8 8 8 0 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 OAJ24340.1 - 0.00058 20.0 0.3 22 5.3 0.1 4.7 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 BP28CT PF08146.12 OAJ24340.1 - 0.0009 19.1 0.0 0.47 10.3 0.0 4.3 4 1 0 4 4 4 1 BP28CT (NUC211) domain Arm PF00514.23 OAJ24340.1 - 0.12 12.5 9.4 30 4.9 0.1 6.9 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat PHD PF00628.29 OAJ24341.1 - 6e-08 32.5 6.1 1.2e-07 31.5 6.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ24341.1 - 0.0027 17.2 8.6 0.0048 16.4 8.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 OAJ24341.1 - 0.13 12.3 3.2 0.25 11.4 3.2 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_4 PF16866.5 OAJ24341.1 - 0.31 11.2 3.8 0.63 10.2 3.8 1.5 1 0 0 1 1 1 0 PHD-finger Dscam_C PF12355.8 OAJ24341.1 - 0.7 10.9 6.3 0.29 12.1 2.3 2.5 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal MRP-S28 PF10213.9 OAJ24342.1 - 1.7e-26 93.1 0.0 9.2e-26 90.7 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein SR-25 PF10500.9 OAJ24342.1 - 0.031 13.9 12.7 0.048 13.3 12.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.8 OAJ24342.1 - 0.2 11.3 10.1 0.3 10.6 10.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region IMUP PF15761.5 OAJ24342.1 - 0.2 12.3 14.6 0.4 11.4 13.9 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein TPPII_N PF12583.8 OAJ24342.1 - 0.9 10.1 7.3 0.86 10.2 6.0 1.5 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal RAP1 PF07218.11 OAJ24342.1 - 2.5 6.3 4.4 3.3 5.9 4.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sde2_N_Ubi PF13019.6 OAJ24343.1 - 1.3e-39 135.7 1.4 2.2e-39 134.9 0.0 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF755 PF05501.11 OAJ24343.1 - 3.1 8.1 10.7 5.5 7.3 10.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Rotamase PF00639.21 OAJ24343.1 - 8.5 7.4 7.1 0.83 10.7 0.7 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain PNRC PF15365.6 OAJ24344.1 - 1.1e-08 34.7 2.0 1.1e-08 34.7 2.0 3.6 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif CENP-K PF11802.8 OAJ24344.1 - 0.12 12.0 4.3 0.16 11.5 4.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K TFIIF_alpha PF05793.12 OAJ24344.1 - 0.45 9.0 16.4 0.58 8.7 16.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PCI PF01399.27 OAJ24345.1 - 3.5e-15 56.4 0.2 1.2e-14 54.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain FeoC PF09012.10 OAJ24345.1 - 0.00026 21.0 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator FmiP_Thoc5 PF09766.9 OAJ24345.1 - 0.014 14.7 1.4 0.021 14.1 1.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TPR_14 PF13428.6 OAJ24345.1 - 0.051 14.4 0.4 25 6.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3116 PF11313.8 OAJ24345.1 - 0.23 11.4 2.0 1.2 9.1 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3116) TPR_2 PF07719.17 OAJ24345.1 - 1.2 9.4 4.3 36 4.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DDRGK PF09756.9 OAJ24345.1 - 1.2 8.7 0.0 1.2 8.7 0.0 2.9 3 1 0 3 3 3 0 DDRGK domain Raptor_N PF14538.6 OAJ24346.1 - 2e-50 170.6 0.0 3.9e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OAJ24346.1 - 4.6e-07 30.4 2.9 1.2 10.1 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat HEAT PF02985.22 OAJ24346.1 - 0.00011 22.2 3.6 0.047 14.0 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 OAJ24346.1 - 0.027 14.5 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF1508 PF07411.12 OAJ24346.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Spt20 PF12090.8 OAJ24346.1 - 1.4 8.4 14.3 2.6 7.6 14.3 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 OAJ24346.1 - 2.8 7.0 8.9 5.8 5.9 8.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF2722 PF10846.8 OAJ24346.1 - 4 6.3 14.7 0.19 10.6 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 OAJ24346.1 - 4.6 7.2 7.4 9 6.3 7.4 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Acetyltransf_1 PF00583.25 OAJ24347.1 - 7.3e-11 42.3 0.0 9.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ24347.1 - 6.7e-08 32.9 0.0 9.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ24347.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ24347.1 - 0.00056 19.8 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAJ24347.1 - 0.0029 17.7 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAJ24347.1 - 0.0046 17.1 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ24347.1 - 0.0057 17.3 0.0 0.0076 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ24347.1 - 0.0085 16.2 0.3 0.38 10.9 0.3 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CLASP_N PF12348.8 OAJ24348.1 - 8.1e-66 221.8 5.1 5.3e-53 179.9 0.3 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 OAJ24348.1 - 0.00043 20.3 7.1 0.083 13.2 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat DUF3361 PF11841.8 OAJ24348.1 - 0.0079 16.1 0.1 0.57 10.1 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 OAJ24348.1 - 0.016 15.2 0.1 4.1 7.4 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 INTS5_C PF14838.6 OAJ24348.1 - 0.15 10.7 0.7 9.2 4.8 0.1 2.2 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus HEAT_2 PF13646.6 OAJ24348.1 - 1.6 9.2 16.4 2.2 8.7 0.0 5.8 5 1 1 6 6 6 0 HEAT repeats Aldo_ket_red PF00248.21 OAJ24351.1 - 3.7e-48 164.2 0.0 4.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 OAJ24352.1 - 1.4e-47 162.6 0.1 5.3e-24 85.1 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ24352.1 - 1.2e-30 106.9 0.0 2.5e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ24352.1 - 7.7e-06 26.1 0.2 2.6e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ24352.1 - 1.8e-05 24.0 0.5 0.00071 18.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ24352.1 - 3.6e-05 23.0 0.0 5.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAJ24352.1 - 0.00081 18.7 0.1 0.0022 17.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ24352.1 - 0.005 16.5 1.7 0.0089 15.7 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ24352.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAJ24352.1 - 0.023 13.4 0.1 0.077 11.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 OAJ24352.1 - 0.033 14.5 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 OAJ24352.1 - 0.047 12.9 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAJ24352.1 - 0.072 13.1 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ24352.1 - 0.083 12.1 0.1 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_6 PF00970.24 OAJ24354.1 - 3.2e-33 114.0 0.0 5.2e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ24354.1 - 2.3e-30 105.4 0.0 4.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAJ24354.1 - 2.8e-06 27.6 0.0 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Adeno_knob PF00541.17 OAJ24354.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) IQ PF00612.27 OAJ24357.1 - 0.002 17.8 0.2 0.0045 16.7 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DNA_pol_phi PF04931.13 OAJ24357.1 - 3.7 5.5 11.2 5.9 4.9 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4604 PF15377.6 OAJ24358.1 - 0.11 12.9 13.3 0.18 12.2 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Paramyxo_ncap PF00973.19 OAJ24358.1 - 0.24 10.3 5.2 0.25 10.2 5.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 OAJ24358.1 - 0.56 8.4 10.6 0.6 8.3 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 OAJ24358.1 - 1.6 8.8 17.6 2 8.5 17.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF501 PF04417.12 OAJ24358.1 - 5.8 6.7 9.1 0.2 11.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) PPP4R2 PF09184.11 OAJ24358.1 - 6.6 6.2 11.8 9.5 5.7 11.8 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 OAJ24358.1 - 7.5 5.2 6.4 7.4 5.2 6.4 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 OAJ24360.1 - 1.6e-08 35.0 0.5 0.029 14.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ24360.1 - 7.2e-08 32.5 2.0 0.038 14.3 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ24360.1 - 9.6e-07 28.7 0.5 0.13 12.9 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAJ24360.1 - 1.5e-05 25.4 0.3 0.47 11.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 OAJ24360.1 - 0.00083 19.2 0.0 0.0032 17.3 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.30 OAJ24360.1 - 0.055 13.9 10.4 0.52 10.9 0.1 4.2 5 0 0 5 5 5 0 Ankyrin repeat Spc7 PF08317.11 OAJ24360.1 - 0.31 9.9 1.4 0.49 9.2 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SET PF00856.28 OAJ24362.1 - 8e-18 65.4 1.2 2.2e-16 60.7 0.0 3.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAJ24362.1 - 1.1e-14 55.0 10.5 1.1e-14 55.0 10.5 1.8 2 0 0 2 2 2 1 Pre-SET motif preSET_CXC PF18264.1 OAJ24362.1 - 0.024 15.1 2.6 0.024 15.1 2.6 3.1 4 0 0 4 4 4 0 CXC domain eIF3_subunit PF08597.10 OAJ24362.1 - 0.073 13.0 4.5 0.15 12.0 4.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 OAJ24362.1 - 2 6.6 6.2 3.6 5.8 6.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DHHA2 PF02833.14 OAJ24363.1 - 0.00091 19.4 0.0 0.00092 19.4 0.0 1.1 1 0 0 1 1 1 1 DHHA2 domain KDZ PF18758.1 OAJ24365.1 - 5.6e-48 163.5 0.0 7.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Hydrolase_4 PF12146.8 OAJ24366.1 - 0.00032 20.0 0.1 0.4 9.9 0.1 2.7 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ24366.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 3.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ24366.1 - 0.097 12.8 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein CDP-OH_P_transf PF01066.21 OAJ24368.1 - 9.6e-10 39.1 0.8 9.6e-10 39.1 0.8 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GRIM-19 PF06212.12 OAJ24369.1 - 1.3e-31 109.3 0.0 1.5e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Benyvirus_P25 PF05744.11 OAJ24370.1 - 0.06 12.6 0.1 0.063 12.6 0.1 1.0 1 0 0 1 1 1 0 Benyvirus P25/P26 protein DUF4781 PF16013.5 OAJ24371.1 - 0.014 14.2 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Ail_Lom PF06316.11 OAJ24371.1 - 0.04 13.6 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Alpha_GJ PF03229.13 OAJ24371.1 - 0.067 13.7 2.5 14 6.3 0.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DDE_3 PF13358.6 OAJ24372.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DSPc PF00782.20 OAJ24373.1 - 8.5e-12 45.0 0.0 1.6e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ24373.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RCC1 PF00415.18 OAJ24377.1 - 1.1e-15 58.0 12.6 0.00015 22.3 0.1 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ24377.1 - 1.2e-06 28.2 19.6 0.46 10.4 0.1 7.4 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat tRNA-synt_1b PF00579.25 OAJ24378.1 - 8.9e-68 228.7 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Choline_kinase PF01633.20 OAJ24379.1 - 1.1e-33 116.6 0.0 5.7e-22 78.3 0.0 2.8 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.23 OAJ24379.1 - 0.018 15.0 0.1 0.51 10.2 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallopep PF12044.8 OAJ24380.1 - 2.7e-85 286.6 0.0 5.4e-35 120.8 0.0 3.1 3 0 0 3 3 3 3 Putative peptidase family Peptidase_M66 PF10462.9 OAJ24380.1 - 0.0014 17.6 0.2 0.0025 16.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Jacalin PF01419.17 OAJ24380.1 - 0.004 17.1 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 OAJ24380.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 Matrixin Thymidylate_kin PF02223.17 OAJ24382.1 - 9.3e-45 152.6 0.0 1.2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 OAJ24382.1 - 7.6e-05 23.0 0.0 0.00012 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ24382.1 - 0.00055 20.1 0.5 0.013 15.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.10 OAJ24382.1 - 0.0021 17.5 0.0 0.005 16.3 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 OAJ24382.1 - 0.058 13.8 0.8 0.23 11.8 0.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 OAJ24382.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GCV_T PF01571.21 OAJ24383.1 - 1.4e-84 283.5 0.0 1.7e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OAJ24383.1 - 2.4e-21 75.4 0.0 5e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 OAJ24383.1 - 0.0022 18.2 0.0 0.0071 16.5 0.0 1.9 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family DUF4946 PF16304.5 OAJ24383.1 - 0.057 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Gpr1_Fun34_YaaH PF01184.19 OAJ24384.1 - 1.5e-27 96.5 13.9 2.1e-27 96.1 13.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ycf4 PF02392.16 OAJ24384.1 - 1.7 8.2 4.2 0.49 10.0 0.5 1.9 2 0 0 2 2 2 0 Ycf4 DNA_ligase_A_M PF01068.21 OAJ24385.1 - 3.4e-07 30.1 0.0 4.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain L51_S25_CI-B8 PF05047.16 OAJ24386.1 - 8.4e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lactamase_B_2 PF12706.7 OAJ24387.1 - 2.8e-07 30.3 0.0 3e-05 23.6 0.0 2.7 2 1 1 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OAJ24387.1 - 5.3e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OAJ24387.1 - 0.00017 21.6 0.0 0.00055 20.0 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 OAJ24387.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II COesterase PF00135.28 OAJ24388.1 - 5.3e-07 28.9 0.2 9.4e-07 28.1 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ24388.1 - 0.00019 21.3 0.8 0.0029 17.5 0.0 3.0 3 1 1 4 4 4 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ24388.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ24388.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FHA PF00498.26 OAJ24389.1 - 0.00017 21.9 0.5 0.0003 21.1 0.5 1.4 1 0 0 1 1 1 1 FHA domain HIP1_clath_bdg PF16515.5 OAJ24389.1 - 0.14 12.8 1.8 1.3 9.7 0.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SH3_1 PF00018.28 OAJ24390.1 - 6.9e-38 128.0 8.5 5.1e-16 58.0 0.2 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAJ24390.1 - 9.3e-37 124.7 10.9 2.3e-13 49.8 0.3 4.0 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 OAJ24390.1 - 1.2e-28 98.7 0.0 2.4e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 OAJ24390.1 - 6.7e-21 73.7 0.0 3.6e-07 29.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 OAJ24390.1 - 0.00027 20.8 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 OAJ24390.1 - 0.0015 18.5 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 OAJ24390.1 - 0.0038 17.5 2.3 0.086 13.1 0.1 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain PfkB PF00294.24 OAJ24391.1 - 1.5e-59 201.8 0.3 1.7e-59 201.6 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAJ24391.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Asp PF00026.23 OAJ24392.1 - 3.6e-114 381.4 0.2 4.3e-114 381.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ24392.1 - 3.9e-16 59.8 0.8 8.6e-14 52.2 0.8 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ24392.1 - 2.1e-05 24.4 0.0 0.0005 19.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAJ24392.1 - 0.00042 20.9 0.0 0.36 11.5 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ24392.1 - 0.0038 17.7 0.0 2.2 8.9 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF3564 PF12087.8 OAJ24392.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) BDHCT_assoc PF16204.5 OAJ24392.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Aldo_ket_red PF00248.21 OAJ24393.1 - 2.8e-43 148.2 0.2 3.3e-41 141.4 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.18 OAJ24394.1 - 3.8e-49 165.1 9.2 6.5e-07 29.9 0.0 8.7 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ24394.1 - 5.8e-32 108.8 29.6 2.8e-06 27.0 0.1 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Nup96 PF12110.8 OAJ24395.1 - 3.7e-90 302.0 0.4 5.8e-90 301.4 0.4 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAJ24395.1 - 2.7e-50 170.4 0.0 4.5e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAJ24395.1 - 3.4e-25 88.7 270.8 3.2e-11 43.9 27.4 12.4 4 3 10 14 14 14 9 Nucleoporin FG repeat region PPP4R2 PF09184.11 OAJ24395.1 - 0.38 10.3 7.4 0.64 9.6 7.4 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAJ24395.1 - 3.1 7.0 8.1 5.2 6.3 8.1 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 OAJ24395.1 - 9.6 5.9 13.3 77 3.0 0.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CBFD_NFYB_HMF PF00808.23 OAJ24396.1 - 2.9e-15 56.3 0.3 5e-15 55.5 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ24396.1 - 1.4e-12 48.1 1.4 3.9e-12 46.7 1.4 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 OAJ24396.1 - 0.033 14.0 0.6 0.054 13.2 0.4 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BUD22 PF09073.10 OAJ24398.1 - 1 8.6 20.8 1.1 8.5 20.8 1.0 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 OAJ24398.1 - 4 6.5 30.4 2.6 7.1 21.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Dicty_REP PF05086.12 OAJ24398.1 - 5.7 4.8 7.5 6.8 4.5 7.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.12 OAJ24398.1 - 5.8 5.0 17.4 7.1 4.7 17.4 1.2 1 0 0 1 1 1 0 Nop14-like family Kelch_4 PF13418.6 OAJ24399.1 - 2.9e-28 97.6 15.7 2.9e-08 33.6 0.1 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ24399.1 - 2.2e-25 88.4 23.1 1.7e-08 34.5 0.3 6.8 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ24399.1 - 3.5e-23 81.1 7.6 1.3e-06 28.2 0.0 6.1 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 OAJ24399.1 - 6.1e-21 74.3 0.7 6.1e-21 74.3 0.7 3.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 OAJ24399.1 - 2.9e-19 68.6 11.0 4.2e-06 26.8 0.1 6.1 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OAJ24399.1 - 3.7e-14 52.0 6.2 4.4e-06 26.2 0.0 5.7 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OAJ24399.1 - 1.8e-11 43.5 3.2 0.00029 20.7 0.0 5.6 5 1 0 5 5 5 3 Kelch motif S36_mt PF10937.8 OAJ24404.1 - 7.2e-08 34.0 7.2 3.6e-07 31.8 7.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Adenylsucc_synt PF00709.21 OAJ24407.1 - 1.1e-174 581.3 0.0 1.3e-174 581.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Serinc PF03348.15 OAJ24408.1 - 3.9e-152 507.1 5.7 4.7e-152 506.9 5.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YqhR PF11085.8 OAJ24408.1 - 0.055 13.4 3.0 0.09 12.7 2.3 1.7 1 1 0 1 1 1 0 Conserved membrane protein YqhR Pkinase PF00069.25 OAJ24409.1 - 4.6e-07 29.5 0.0 3e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24409.1 - 0.0032 16.8 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase AAA PF00004.29 OAJ24410.1 - 0.00043 20.7 0.2 0.0033 17.9 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ24410.1 - 0.039 14.4 0.3 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 OAJ24410.1 - 0.039 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_Ag35 PF03286.14 OAJ24410.1 - 0.17 11.7 0.5 0.36 10.6 0.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TIP49 PF06068.13 OAJ24410.1 - 0.26 10.5 0.0 0.39 9.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain RIBIOP_C PF04950.12 OAJ24412.1 - 1.6e-84 283.8 0.0 1.6e-84 283.8 0.0 1.8 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAJ24412.1 - 6.3e-32 109.5 0.0 1.7e-31 108.1 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 OAJ24412.1 - 2.5e-05 24.8 4.5 2.6e-05 24.7 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain GTP_EFTU PF00009.27 OAJ24412.1 - 7.5e-05 22.3 0.0 0.0039 16.8 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAJ24412.1 - 0.0001 22.6 0.0 0.00034 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ24412.1 - 0.00023 21.3 1.6 0.00075 19.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OAJ24412.1 - 0.0013 18.5 0.1 0.0044 16.8 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OAJ24412.1 - 0.0022 17.9 0.2 0.0058 16.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 OAJ24412.1 - 0.0058 17.1 0.6 0.012 16.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAJ24412.1 - 0.01 15.9 0.1 0.048 13.8 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OAJ24412.1 - 0.013 15.1 0.0 0.043 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ24412.1 - 0.03 14.7 0.0 0.076 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OAJ24412.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ24412.1 - 0.034 14.6 1.4 0.071 13.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 OAJ24412.1 - 0.05 14.2 0.3 0.27 11.8 0.0 2.5 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 OAJ24412.1 - 0.059 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OAJ24412.1 - 0.065 13.1 0.5 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 OAJ24412.1 - 0.095 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 OAJ24412.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OAJ24412.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OAJ24412.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region OsmC PF02566.19 OAJ24413.1 - 7.2e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein Nop14 PF04147.12 OAJ24414.1 - 0.066 11.4 1.6 0.15 10.2 1.6 1.6 1 0 0 1 1 1 0 Nop14-like family FAM60A PF15396.6 OAJ24417.1 - 2.5 8.1 11.3 5.7 6.9 11.3 1.6 1 0 0 1 1 1 0 Protein Family FAM60A EF-hand_1 PF00036.32 OAJ24418.1 - 2.4e-06 26.7 0.2 2.7e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OAJ24418.1 - 6.9e-06 25.6 0.1 3.3e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OAJ24418.1 - 1.4e-05 25.5 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAJ24418.1 - 0.006 16.0 0.0 0.02 14.4 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OAJ24418.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF4211 PF13926.6 OAJ24419.1 - 8.4e-05 22.7 0.3 0.00047 20.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) RRM_1 PF00076.22 OAJ24420.1 - 9.1e-17 60.7 0.0 1.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ24420.1 - 3e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif P19Arf_N PF07392.12 OAJ24420.1 - 0.27 11.7 1.2 0.87 10.1 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus GPI2 PF06432.11 OAJ24421.1 - 7.7e-73 245.4 0.0 9.5e-72 241.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase EcsB PF05975.12 OAJ24421.1 - 0.26 10.1 4.0 2.9 6.6 0.3 2.5 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB GCIP PF13324.6 OAJ24422.1 - 0.00042 20.0 14.6 0.00042 20.0 14.6 2.9 2 1 1 3 3 3 1 Grap2 and cyclin-D-interacting CNDH2_C PF16858.5 OAJ24422.1 - 0.0091 15.9 4.0 0.018 14.9 4.0 1.5 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 OAJ24422.1 - 5.8 5.6 5.7 8.8 5.0 5.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 OAJ24422.1 - 7.5 6.3 14.5 1.5 8.6 8.0 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Peptidase_S10 PF00450.22 OAJ24423.1 - 1.7e-89 301.1 0.0 2.4e-89 300.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sporozoite_P67 PF05642.11 OAJ24423.1 - 7.2 4.6 5.6 11 4.0 5.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Keratin_2_head PF16208.5 OAJ24423.1 - 7.7 6.6 18.0 20 5.3 18.0 1.7 1 0 0 1 1 1 0 Keratin type II head Arrestin_C PF02752.22 OAJ24424.1 - 2.5e-07 31.2 0.0 1.9e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ24424.1 - 0.00063 19.8 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Serglycin PF04360.12 OAJ24424.1 - 0.098 12.6 9.2 1.9 8.4 1.6 3.3 2 0 0 2 2 2 0 Serglycin MG2 PF01835.19 OAJ24424.1 - 0.12 12.9 0.1 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 MG2 domain NDK PF00334.19 OAJ24425.1 - 1.4e-53 180.5 0.0 1.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 OAJ24425.1 - 0.0083 16.6 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ Peptidase_C97 PF05903.14 OAJ24430.1 - 9.4e-38 129.4 0.0 2.7e-37 127.9 0.0 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain SRR1 PF07985.12 OAJ24430.1 - 2.2e-13 50.0 0.3 4.2e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 SRR1 tRNA-synt_1d PF00750.19 OAJ24432.1 - 3.5e-96 322.2 2.0 4.8e-96 321.7 2.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAJ24432.1 - 1.1e-20 73.9 0.0 4.8e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain POT1 PF02765.17 OAJ24432.1 - 0.0095 15.8 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 WAC_Acf1_DNA_bd PF10537.9 OAJ24433.1 - 1.2e-32 112.4 0.0 3.4e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAJ24433.1 - 2.8e-25 88.7 0.5 2.8e-25 88.7 0.5 2.9 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAJ24433.1 - 4.5e-11 42.9 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 OAJ24433.1 - 6.9e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PPP4R2 PF09184.11 OAJ24434.1 - 0.014 15.0 5.6 0.019 14.5 5.6 1.3 1 0 0 1 1 1 0 PPP4R2 FancD2 PF14631.6 OAJ24434.1 - 0.12 9.8 1.8 0.15 9.4 1.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Nop14 PF04147.12 OAJ24434.1 - 0.17 10.1 10.4 0.21 9.8 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 OAJ24434.1 - 0.24 10.8 1.5 0.38 10.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_Ag35 PF03286.14 OAJ24434.1 - 0.29 10.9 6.9 0.49 10.1 6.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 OAJ24434.1 - 0.33 9.2 4.9 0.4 8.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 OAJ24434.1 - 0.83 9.5 9.2 1.5 8.7 9.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 OAJ24434.1 - 2.8 7.3 7.9 4.6 6.6 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 OAJ24434.1 - 3.5 5.6 18.6 5.1 5.1 18.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 OAJ24434.1 - 4.5 6.2 9.1 7.8 5.4 9.1 1.4 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 OAJ24434.1 - 5.4 6.2 11.3 8.7 5.6 11.3 1.3 1 0 0 1 1 1 0 NOA36 protein NARP1 PF12569.8 OAJ24434.1 - 6.1 5.6 6.7 9.4 5.0 6.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM176 PF14851.6 OAJ24434.1 - 7.1 6.3 7.7 14 5.3 7.7 1.5 1 0 0 1 1 1 0 FAM176 family ORC_WH_C PF18137.1 OAJ24434.1 - 7.1 6.7 14.8 0.99 9.5 0.1 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Nop14 PF04147.12 OAJ24436.1 - 0.62 8.2 22.8 0.79 7.9 22.8 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ24436.1 - 2.1 6.6 14.3 3.2 6.0 14.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 OAJ24436.1 - 8.4 4.8 15.3 13 4.2 15.3 1.3 1 0 0 1 1 1 0 Utp14 protein DUF1793 PF08760.11 OAJ24437.1 - 3e-65 219.7 1.0 8e-65 218.3 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAJ24437.1 - 8.6e-65 217.6 0.0 1.4e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAJ24437.1 - 3.4e-46 157.8 2.9 9e-46 156.5 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ24437.1 - 3.8e-07 29.6 1.4 0.029 13.9 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ24437.1 - 0.0014 18.2 0.2 0.0032 17.0 0.2 1.6 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term MutL_C PF08676.11 OAJ24440.1 - 5.6e-22 78.1 0.1 3.5e-21 75.5 0.1 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAJ24440.1 - 3.2e-16 59.1 0.0 7.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAJ24440.1 - 1.4e-11 44.4 0.4 8e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ24440.1 - 1.1e-07 32.3 0.0 3.9e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ccdc124 PF06244.12 OAJ24441.1 - 1e-15 58.4 10.1 3e-12 47.2 9.0 2.3 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 124 /Oxs1 CBP4 PF07960.11 OAJ24441.1 - 0.96 9.3 4.9 0.25 11.2 0.5 2.2 1 1 1 2 2 2 0 CBP4 HSP70 PF00012.20 OAJ24442.1 - 1.8e-64 218.0 0.4 1.1e-38 132.9 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein Actin PF00022.19 OAJ24442.1 - 0.001 17.8 0.0 0.33 9.5 0.0 2.2 2 0 0 2 2 2 2 Actin PilX_N PF14341.6 OAJ24443.1 - 0.06 13.3 1.8 0.16 11.9 1.8 1.8 1 0 0 1 1 1 0 PilX N-terminal An_peroxidase PF03098.15 OAJ24444.1 - 2.3e-30 105.7 0.0 6.5e-21 74.5 0.0 4.5 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAJ24444.1 - 3.8e-15 55.6 0.0 4.6e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 Actin PF00022.19 OAJ24445.1 - 4.1e-112 374.8 0.0 3.3e-111 371.8 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAJ24445.1 - 0.029 13.2 0.0 0.24 10.2 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein RINGv PF12906.7 OAJ24446.1 - 8.8e-15 54.6 11.3 1.6e-14 53.7 11.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAJ24446.1 - 0.11 12.8 10.6 0.23 11.8 10.6 1.5 1 0 0 1 1 1 0 Ring finger domain DUF2968 PF11180.8 OAJ24446.1 - 1.2 8.7 4.6 2.8 7.6 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HemY_N PF07219.13 OAJ24446.1 - 1.8 8.8 8.5 0.79 9.9 0.4 3.4 3 0 0 3 3 3 0 HemY protein N-terminus FANCL_C PF11793.8 OAJ24446.1 - 4.2 7.6 8.5 10 6.4 8.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RHD3 PF05879.12 OAJ24451.1 - 3.7e-247 822.2 0.0 4.6e-247 821.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 OAJ24451.1 - 2e-05 24.6 0.0 5.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAJ24451.1 - 2.6e-05 24.4 0.3 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GBP PF02263.19 OAJ24451.1 - 5.9e-05 22.5 0.2 0.00012 21.4 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 OAJ24451.1 - 0.009 16.3 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF4259 PF14078.6 OAJ24451.1 - 0.047 14.4 0.4 0.11 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) AAA_16 PF13191.6 OAJ24451.1 - 0.15 12.4 2.1 1.3 9.3 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain DUF21 PF01595.20 OAJ24452.1 - 5.5e-37 127.2 0.3 5.5e-37 127.2 0.3 1.6 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAJ24452.1 - 0.023 15.1 1.5 7.1 7.2 0.1 3.5 3 0 0 3 3 3 0 CBS domain NDC10_II PF16787.5 OAJ24453.1 - 4.9e-53 180.2 0.0 7.3e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 MFS_1 PF07690.16 OAJ24454.1 - 5.5e-33 114.4 34.4 4.9e-31 107.9 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ24454.1 - 7.3e-10 38.3 15.0 1.9e-09 37.0 15.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ24454.1 - 2.7e-06 26.1 4.8 5.8e-06 25.0 3.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 OAJ24454.1 - 0.32 11.0 2.8 0.25 11.3 0.2 2.1 3 0 0 3 3 3 0 HCMV UL42 DDE_Tnp_4 PF13359.6 OAJ24455.1 - 1.2e-21 77.1 0.0 1.5e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ24455.1 - 5.7e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ24455.1 - 0.013 15.1 0.0 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Plant transposon protein BCA_ABC_TP_C PF12399.8 OAJ24455.1 - 0.029 14.3 0.3 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DDE_Tnp_1_2 PF13586.6 OAJ24455.1 - 0.074 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 OAJ24456.1 - 4.4e-15 56.4 0.5 7.3e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HHH_8 PF14716.6 OAJ24456.1 - 0.0066 16.8 0.9 0.019 15.3 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Myb_DNA-bind_4 PF13837.6 OAJ24456.1 - 0.33 11.4 4.0 0.081 13.3 0.6 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sec2p PF06428.11 OAJ24457.1 - 9.4e-18 64.0 8.8 2.4e-17 62.7 8.8 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Roughex PF06020.11 OAJ24457.1 - 0.19 10.8 9.6 0.4 9.7 9.6 1.5 1 0 0 1 1 1 0 Drosophila roughex protein SlyX PF04102.12 OAJ24457.1 - 2.2 8.9 7.5 4 8.1 0.2 3.4 2 1 0 3 3 3 0 SlyX HAT_KAT11 PF08214.11 OAJ24458.1 - 2.2e-26 93.0 0.1 3.2e-14 53.0 0.0 4.4 3 2 0 3 3 3 2 Histone acetylation protein zf-PARP PF00645.18 OAJ24458.1 - 8.7e-20 71.4 0.0 2.6e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 OAJ24458.1 - 0.043 13.7 1.6 0.21 11.6 1.6 2.3 1 0 0 1 1 1 0 AT hook motif Transp_cyt_pur PF02133.15 OAJ24459.1 - 5.9e-19 68.2 31.4 8e-19 67.7 31.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Lyase_aromatic PF00221.19 OAJ24460.1 - 2.8e-120 402.1 2.8 4e-120 401.6 2.8 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase Nitroreductase PF00881.24 OAJ24460.1 - 0.031 14.3 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 Nitroreductase family TBCA PF02970.16 OAJ24461.1 - 2.6e-27 95.0 5.1 2.6e-27 95.0 5.1 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor A TaqI_C PF12950.7 OAJ24461.1 - 0.11 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain eIF-4B PF06273.11 OAJ24461.1 - 0.13 11.3 4.5 0.14 11.2 4.5 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Phage_Gp23 PF10669.9 OAJ24461.1 - 0.21 11.9 8.3 0.046 14.1 5.1 1.5 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Atg14 PF10186.9 OAJ24461.1 - 4.6 6.2 10.0 5 6.1 10.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 OAJ24461.1 - 6.6 6.0 10.7 7.6 5.8 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rad52_Rad22 PF04098.15 OAJ24462.1 - 7.7e-56 188.3 0.0 1.2e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein CENP-F_N PF10481.9 OAJ24463.1 - 0.049 13.3 0.1 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain Abhydrolase_1 PF00561.20 OAJ24465.1 - 2.5e-16 60.1 0.0 6.1e-13 49.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ24465.1 - 2.2e-15 56.6 0.0 6.8e-15 55.0 0.0 1.8 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.7 OAJ24465.1 - 2e-05 25.3 7.2 7.7e-05 23.4 2.1 2.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family V4R PF02830.18 OAJ24465.1 - 0.15 12.1 0.5 0.38 10.8 0.1 1.9 1 1 1 2 2 2 0 V4R domain Dec-1 PF04624.14 OAJ24465.1 - 0.26 11.1 3.3 2.4 8.1 0.4 2.3 2 0 0 2 2 2 0 Dec-1 repeat Aminotran_5 PF00266.19 OAJ24466.1 - 2.3e-35 122.2 0.0 2.6e-34 118.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Ig_4 PF16680.5 OAJ24466.1 - 0.17 12.2 0.0 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain IPPT PF01715.17 OAJ24467.1 - 4e-42 144.6 0.0 1.7e-41 142.5 0.0 1.8 1 1 0 1 1 1 1 IPP transferase AAA_22 PF13401.6 OAJ24467.1 - 0.002 18.4 0.1 0.0064 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ24467.1 - 0.0035 17.9 0.1 0.039 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OAJ24467.1 - 0.05 13.1 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase3 PF18751.1 OAJ24467.1 - 0.056 13.3 0.3 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 OAJ24467.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 OAJ24467.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase IstB_IS21 PF01695.17 OAJ24467.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OAJ24467.1 - 0.081 13.3 0.1 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.18 OAJ24468.1 - 1.3e-19 70.3 0.0 5.1e-19 68.3 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ24468.1 - 4.4e-07 29.9 8.0 4.4e-07 29.9 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.21 OAJ24469.1 - 1.9e-17 63.3 4.8 1.9e-17 63.3 4.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily RecT PF03837.14 OAJ24469.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RecT family DUF202 PF02656.15 OAJ24476.1 - 1.3e-21 76.8 0.2 1.3e-21 76.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glyco_hydro_18 PF00704.28 OAJ24477.1 - 1e-81 275.1 0.0 1.2e-81 274.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LsmAD PF06741.13 OAJ24478.1 - 6.4e-27 93.9 1.2 1.5e-26 92.8 1.2 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 OAJ24478.1 - 4.1e-12 46.1 0.0 7.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DIRP PF06584.13 OAJ24478.1 - 0.2 11.8 0.7 0.42 10.8 0.7 1.4 1 0 0 1 1 1 0 DIRP L31 PF09784.9 OAJ24479.1 - 5.2e-43 145.6 0.5 5.9e-43 145.4 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Na_H_Exchanger PF00999.21 OAJ24481.1 - 3.2e-44 151.3 18.7 4.2e-44 150.9 18.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_3_3 PF16083.5 OAJ24481.1 - 0.087 13.0 0.2 0.087 13.0 0.2 3.3 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III TMEM238 PF15125.6 OAJ24481.1 - 7.6 6.8 13.6 0.32 11.2 1.3 3.3 3 0 0 3 3 3 0 TMEM238 protein family HSF_DNA-bind PF00447.17 OAJ24482.1 - 1.3e-31 109.0 0.1 1.3e-31 109.0 0.1 2.5 2 0 0 2 2 2 1 HSF-type DNA-binding FA_desaturase PF00487.24 OAJ24483.1 - 1.2e-23 84.3 26.7 7.6e-23 81.6 26.7 2.0 1 1 0 1 1 1 1 Fatty acid desaturase Metallophos PF00149.28 OAJ24484.1 - 1e-27 98.0 0.0 1.3e-26 94.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OAJ24484.1 - 7.9e-18 64.5 0.0 1.8e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 OAJ24484.1 - 3.7e-14 51.8 0.9 3.2e-06 26.7 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ24484.1 - 7e-09 35.1 3.3 0.003 17.6 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ24484.1 - 0.00052 20.2 0.1 0.14 12.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ24484.1 - 0.0081 16.3 0.5 0.48 10.8 0.0 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ24484.1 - 0.011 14.9 0.0 0.35 10.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ24484.1 - 0.017 14.8 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 OAJ24484.1 - 0.088 13.7 0.2 13 6.9 0.0 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ24484.1 - 0.19 12.0 1.5 5.6 7.3 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat CoA_trans PF01144.23 OAJ24486.1 - 1.1e-104 348.6 0.2 2.6e-64 216.6 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 OAJ24486.1 - 0.14 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 OAJ24486.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Y_phosphatase2 PF03162.13 OAJ24487.1 - 2.3e-30 105.4 0.0 1.3e-23 83.4 0.0 3.1 3 0 0 3 3 3 3 Tyrosine phosphatase family Cas_GSU0054 PF09609.10 OAJ24488.1 - 0.0058 15.4 0.4 0.011 14.5 0.4 1.3 1 0 0 1 1 1 1 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Sds3 PF08598.11 OAJ24489.1 - 6.2e-29 101.6 2.3 1.2e-28 100.6 2.3 1.5 1 0 0 1 1 1 1 Sds3-like MULE PF10551.9 OAJ24490.1 - 1.8e-11 44.3 0.0 5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain LEAP-2 PF07359.11 OAJ24490.1 - 0.0027 17.5 0.1 0.0069 16.2 0.1 1.6 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Transposase_mut PF00872.18 OAJ24490.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family SWIM PF04434.17 OAJ24490.1 - 0.023 14.4 1.5 0.058 13.1 0.0 2.3 2 0 0 2 2 2 0 SWIM zinc finger MAPEG PF01124.18 OAJ24491.1 - 7e-26 90.7 0.6 8.1e-26 90.5 0.6 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M3 PF01432.20 OAJ24491.1 - 0.36 10.1 0.9 8.9 5.4 0.4 2.0 1 1 1 2 2 2 0 Peptidase family M3 MFS_1 PF07690.16 OAJ24492.1 - 5.3e-35 121.0 11.8 5.3e-35 121.0 11.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ24492.1 - 5.9e-08 32.0 1.8 5.9e-08 32.0 1.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAJ24492.1 - 0.0035 15.8 0.9 0.0059 15.1 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nuc_H_symport PF03825.16 OAJ24492.1 - 0.013 14.5 7.5 0.028 13.4 0.7 2.4 2 0 0 2 2 2 0 Nucleoside H+ symporter Ada_Zn_binding PF02805.16 OAJ24493.1 - 1.9e-20 72.7 8.9 3.3e-20 71.9 8.9 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAJ24493.1 - 0.004 17.2 0.1 0.0084 16.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family ADIP PF11559.8 OAJ24494.1 - 2.2e-20 73.3 4.5 3.9e-20 72.5 4.5 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CCDC144C PF14915.6 OAJ24494.1 - 0.0049 16.0 8.1 0.0076 15.4 8.1 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF1664 PF07889.12 OAJ24494.1 - 0.17 12.0 2.8 0.33 11.0 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OAJ24494.1 - 0.31 11.6 7.8 0.4 11.2 6.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ERM PF00769.19 OAJ24494.1 - 7 6.4 14.7 13 5.5 14.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HAUS-augmin3 PF14932.6 OAJ24494.1 - 8.5 5.9 9.9 19 4.8 7.2 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Asp PF00026.23 OAJ24495.1 - 1.7e-64 218.2 0.0 2.2e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ24495.1 - 2.3e-11 44.2 0.8 9.9e-09 35.7 0.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ24495.1 - 2.1e-05 25.1 0.6 0.013 16.1 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ24495.1 - 0.00016 22.1 0.2 0.014 16.0 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease adh_short PF00106.25 OAJ24496.1 - 1.7e-45 154.9 0.2 2.3e-45 154.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24496.1 - 2.6e-31 109.0 0.1 3.6e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ24496.1 - 6.6e-14 52.2 3.3 5e-13 49.4 3.2 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ24496.1 - 2.1e-06 27.4 0.2 1.6e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ24496.1 - 5.6e-05 22.7 0.0 8.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ24496.1 - 0.00055 19.0 0.4 0.00082 18.5 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ24496.1 - 0.0024 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FAD_binding_3 PF01494.19 OAJ24496.1 - 0.013 14.8 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Urocanase PF01175.18 OAJ24496.1 - 0.036 13.7 0.3 0.058 13.0 0.1 1.4 1 1 0 1 1 1 0 Urocanase Rossmann-like domain NAD_binding_10 PF13460.6 OAJ24496.1 - 0.039 13.8 0.9 0.061 13.2 0.9 1.6 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 OAJ24496.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RAI1 PF08652.11 OAJ24497.1 - 2.4e-21 75.7 0.0 6.1e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Lipase_GDSL_2 PF13472.6 OAJ24504.1 - 1.7e-05 25.3 0.0 2.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAJ24504.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase E1-E2_ATPase PF00122.20 OAJ24505.1 - 3.9e-47 160.1 3.0 7.3e-47 159.2 3.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ24505.1 - 2.6e-30 106.3 1.4 1.1e-23 84.7 0.1 3.4 4 1 0 4 4 4 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAJ24505.1 - 3.9e-20 72.1 0.0 1.3e-11 44.8 0.0 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.7 OAJ24505.1 - 0.00096 19.6 0.1 0.0037 17.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ24505.1 - 0.022 14.5 0.4 0.071 12.8 0.7 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 OAJ24505.1 - 3 7.9 8.1 3.4 7.7 2.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) DnaJ PF00226.31 OAJ24506.1 - 2e-14 53.5 0.7 4.2e-14 52.4 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3699 PF12480.8 OAJ24506.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) Ras PF00071.22 OAJ24507.1 - 2.4e-56 189.8 0.3 3e-56 189.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ24507.1 - 1.4e-33 115.6 0.1 2.1e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ24507.1 - 3.1e-13 49.6 0.2 3.7e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ24507.1 - 1.4e-05 24.8 0.2 3.3e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ24507.1 - 0.00021 20.8 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAJ24507.1 - 0.00085 19.4 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sugar_tr PF00083.24 OAJ24508.1 - 3e-118 395.5 13.5 3.9e-118 395.2 13.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ24508.1 - 5e-27 94.8 43.7 9.2e-26 90.6 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.6 OAJ24508.1 - 0.25 11.4 1.5 0.56 10.2 1.5 1.5 1 0 0 1 1 1 0 CoA-binding domain OATP PF03137.20 OAJ24508.1 - 3.8 5.7 7.1 6.5 4.9 2.1 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MIT PF04212.18 OAJ24510.1 - 7.4e-08 32.3 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Myosin_head PF00063.21 OAJ24511.1 - 1.2e-238 793.8 2.5 1.4e-238 793.5 2.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OAJ24511.1 - 4e-49 166.8 0.0 6.2e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 OAJ24511.1 - 4e-10 39.1 0.2 8.4e-10 38.1 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ24511.1 - 1.7e-09 37.4 0.1 4.3e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ24511.1 - 0.00013 21.5 0.0 0.00043 19.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 OAJ24511.1 - 0.0023 18.2 0.7 0.0054 17.0 0.7 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.12 OAJ24511.1 - 0.062 12.8 0.5 9.3 5.7 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 OAJ24511.1 - 0.062 13.7 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAJ24511.1 - 0.062 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ24511.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 OAJ24511.1 - 0.21 11.5 0.2 0.44 10.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain Peptidase_C50 PF03568.17 OAJ24512.1 - 2.4e-107 359.5 0.0 3.2e-107 359.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_7 PF13176.6 OAJ24512.1 - 0.09 12.9 0.3 26 5.1 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ24512.1 - 0.96 9.4 2.8 28 4.8 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ24512.1 - 1.6 9.0 9.7 4.4 7.7 0.8 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L6 PF00347.23 OAJ24513.1 - 8.1e-18 64.9 0.0 1.1e-10 42.1 0.0 3.7 4 0 0 4 4 4 3 Ribosomal protein L6 MULE PF10551.9 OAJ24514.1 - 9.4e-25 86.9 0.2 2.7e-24 85.4 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ24514.1 - 6.4e-06 26.8 0.3 1.3e-05 25.8 0.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Glyco_trans_1_3 PF13528.6 OAJ24514.1 - 0.087 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF5071 PF16804.5 OAJ24514.1 - 0.16 12.3 1.7 2 8.7 0.1 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF5071) Cytomega_UL20A PF05984.12 OAJ24515.1 - 0.21 11.9 5.4 0.17 12.2 3.1 2.0 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein MULE PF10551.9 OAJ24516.1 - 3.4e-17 62.6 0.0 9.6e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ24516.1 - 8.5e-11 41.3 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.15 OAJ24516.1 - 4.7e-06 27.2 0.9 1.2e-05 25.9 0.9 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.17 OAJ24516.1 - 0.0018 17.9 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 OAJ24516.1 - 0.006 16.3 0.1 0.027 14.2 0.0 1.7 1 1 1 2 2 2 1 Transposase DDE_Tnp_IS240 PF13610.6 OAJ24516.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 DDE domain rve PF00665.26 OAJ24516.1 - 0.059 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Striatin PF08232.12 OAJ24517.1 - 3.9e-19 69.8 4.8 1.9e-13 51.3 0.3 2.4 2 1 1 3 3 3 2 Striatin family G-alpha PF00503.20 OAJ24517.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ADIP PF11559.8 OAJ24518.1 - 0.0089 16.1 3.6 0.0089 16.1 3.6 1.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 OAJ24518.1 - 0.011 14.6 5.1 0.015 14.2 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAJ24518.1 - 0.065 12.6 3.3 0.081 12.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OAJ24518.1 - 0.073 11.7 0.2 0.092 11.3 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Filament PF00038.21 OAJ24518.1 - 0.092 12.3 6.0 0.12 11.9 6.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein CHDCT2 PF08074.11 OAJ24518.1 - 0.25 11.5 1.9 0.35 11.0 1.9 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain SPATA24 PF15175.6 OAJ24518.1 - 0.92 9.4 4.8 7.4 6.4 0.7 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 NUFIP1 PF10453.9 OAJ24519.1 - 5e-10 39.1 0.5 1.3e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) NPR3 PF03666.13 OAJ24519.1 - 6.5 5.4 10.6 11 4.6 10.6 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 OAJ24519.1 - 8.5 4.5 16.4 13 4.0 16.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PLDc_2 PF13091.6 OAJ24520.1 - 5.6e-13 48.9 0.0 3.2e-06 27.1 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAJ24520.1 - 9.7e-06 25.6 4.2 0.063 13.5 0.1 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif NIPSNAP PF07978.13 OAJ24525.1 - 1.5e-37 127.9 2.4 6.8e-30 103.3 0.2 2.3 2 0 0 2 2 2 2 NIPSNAP Mito_carr PF00153.27 OAJ24526.1 - 8.5e-62 205.1 3.8 3.6e-21 74.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Carboxyl_trans PF01039.22 OAJ24527.1 - 2.2e-134 448.8 0.0 2.8e-134 448.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 OAJ24527.1 - 0.0072 16.2 0.1 3.2 7.6 0.0 2.7 3 0 0 3 3 3 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ECH_1 PF00378.20 OAJ24527.1 - 0.057 12.7 0.5 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CLPTM1 PF05602.12 OAJ24528.1 - 5.3e-100 335.4 0.0 1.5e-96 324.0 0.0 2.4 1 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OAJ24528.1 - 5.7e-09 35.6 1.0 2.3e-07 30.5 0.5 2.5 2 0 0 2 2 2 1 PQ loop repeat ER_lumen_recept PF00810.18 OAJ24528.1 - 0.13 13.1 2.5 0.32 11.8 2.5 1.7 1 1 0 1 1 1 0 ER lumen protein retaining receptor DUF2417 PF10329.9 OAJ24529.1 - 4.3e-13 49.2 0.0 1.3e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 Region of unknown function (DUF2417) DUF3951 PF13131.6 OAJ24529.1 - 0.017 15.3 2.8 1.4 9.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF2070 PF09843.9 OAJ24529.1 - 4.1 5.6 9.7 6.1 5.0 9.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PDCD2_C PF04194.13 OAJ24531.1 - 8e-28 97.7 12.2 8e-28 97.7 12.2 3.3 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain RXT2_N PF08595.11 OAJ24531.1 - 1 9.4 15.3 2.4 8.2 3.4 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal BSP_II PF05432.11 OAJ24531.1 - 2.8 7.6 15.6 0.037 13.7 4.3 2.6 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 OAJ24531.1 - 7.4 5.8 27.3 5.1 6.3 11.9 2.3 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ24531.1 - 7.6 6.2 33.3 0.43 10.3 10.6 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Glutaredoxin PF00462.24 OAJ24532.1 - 8e-18 64.4 0.0 1.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin NAD_binding_8 PF13450.6 OAJ24533.1 - 1.2e-08 35.0 0.0 3.9e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ24533.1 - 0.006 15.9 0.0 0.083 12.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ24533.1 - 0.025 13.6 0.7 0.064 12.3 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 OAJ24533.1 - 0.031 14.8 0.1 16 6.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ24533.1 - 0.036 13.7 0.6 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ24533.1 - 0.23 10.1 0.1 0.72 8.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Met_10 PF02475.16 OAJ24534.1 - 8e-51 172.6 0.0 3.1e-40 138.1 0.0 2.3 2 0 0 2 2 2 2 Met-10+ like-protein PBD PF00786.28 OAJ24535.1 - 0.0013 19.1 0.0 0.0013 19.1 0.0 2.1 3 0 0 3 3 3 1 P21-Rho-binding domain F-box PF00646.33 OAJ24536.1 - 3.7e-07 29.8 0.1 6.5e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ24536.1 - 0.00012 21.9 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ24536.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 F-box EOS1 PF12326.8 OAJ24538.1 - 0.034 14.1 0.1 0.034 14.1 0.1 1.9 2 0 0 2 2 2 0 N-glycosylation protein DUF1418 PF07214.12 OAJ24538.1 - 5.4 6.9 7.6 1.3 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) PhoD PF09423.10 OAJ24539.1 - 0.00042 19.4 0.0 0.035 13.1 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Dehydrin PF00257.19 OAJ24539.1 - 0.0044 17.6 0.1 0.0096 16.5 0.1 1.5 1 0 0 1 1 1 1 Dehydrin F-box-like PF12937.7 OAJ24540.1 - 1e-05 25.3 0.1 2.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ24540.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ24540.1 - 0.052 13.4 0.2 0.092 12.6 0.2 1.3 1 0 0 1 1 1 0 F-box E3_binding PF02817.17 OAJ24540.1 - 0.081 13.3 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 e3 binding domain LIP PF03583.14 OAJ24541.1 - 4.7e-41 141.0 0.3 3.1e-39 135.0 0.3 2.0 1 1 0 1 1 1 1 Secretory lipase Complex1_LYR PF05347.15 OAJ24542.1 - 2.5e-05 24.2 1.3 0.00019 21.4 1.3 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_23 PF13489.6 OAJ24542.1 - 0.026 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.20 OAJ24542.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_31 PF13847.6 OAJ24542.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF445 PF04286.12 OAJ24543.1 - 0.062 13.1 0.0 0.071 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4692 PF15763.5 OAJ24543.1 - 0.088 13.3 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Spt5_N PF11942.8 OAJ24543.1 - 1.5 9.9 8.9 0.15 13.1 4.0 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_85 PF03644.13 OAJ24545.1 - 3.5e-56 190.8 0.0 4.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SecY PF00344.20 OAJ24547.1 - 0.073 12.3 6.6 0.54 9.4 5.2 2.3 2 1 0 2 2 2 0 SecY translocase DUF3176 PF11374.8 OAJ24547.1 - 0.43 10.8 6.5 1.6 9.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) PH PF00169.29 OAJ24553.1 - 2.7e-05 24.6 0.0 5.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAJ24553.1 - 0.011 16.1 0.2 0.097 13.1 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain NOA36 PF06524.12 OAJ24553.1 - 0.26 10.6 4.8 0.51 9.6 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Anoctamin PF04547.12 OAJ24554.1 - 1.5 7.6 4.4 1.9 7.2 4.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2207 PF09972.9 OAJ24554.1 - 3.4 6.3 16.8 4.2 6.0 16.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPX PF03105.19 OAJ24556.1 - 3.8e-34 119.2 8.3 1.8e-24 87.4 0.6 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 OAJ24556.1 - 3.3e-32 112.1 36.9 4.9e-32 111.6 36.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OAJ24556.1 - 3.5e-27 95.4 38.5 2.4e-20 72.9 9.0 2.3 1 1 1 2 2 2 2 Citrate transporter DUF997 PF06196.12 OAJ24556.1 - 2.2 8.3 8.1 5.9 7.0 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DEAD PF00270.29 OAJ24557.1 - 3.1e-19 69.4 0.3 7.2e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Metallophos PF00149.28 OAJ24557.1 - 3.8e-17 63.5 0.0 8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Helicase_C PF00271.31 OAJ24557.1 - 2.2e-14 53.8 0.1 1e-12 48.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pur_ac_phosph_N PF16656.5 OAJ24557.1 - 4.8e-11 43.1 0.9 4.8e-11 43.1 0.9 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OAJ24557.1 - 5.9e-11 43.1 0.0 1.6e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C RecQ_Zn_bind PF16124.5 OAJ24557.1 - 2.9e-08 34.3 0.0 7e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 RecQ zinc-binding PhoD_N PF16655.5 OAJ24557.1 - 0.0092 16.5 0.0 0.031 14.8 0.0 1.9 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 OAJ24557.1 - 0.0092 16.3 1.0 0.023 15.1 1.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain HEM4 PF02602.15 OAJ24557.1 - 0.039 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Pex24p PF06398.11 OAJ24558.1 - 3.7e-26 92.0 2.0 3.7e-26 92.0 2.0 2.6 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Rad21_Rec8_N PF04825.13 OAJ24560.1 - 1.5e-24 86.2 0.0 2.9e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAJ24560.1 - 1.1e-07 31.0 0.0 2.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SUIM_assoc PF16619.5 OAJ24560.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2236 PF09995.9 OAJ24561.1 - 2e-14 54.4 3.8 2e-14 54.4 3.8 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Fcf1 PF04900.12 OAJ24562.1 - 5.1e-17 62.1 0.0 9.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Fcf1 mRNA_triPase PF02940.15 OAJ24563.1 - 8.3e-48 163.0 0.1 9.7e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CPSF_A PF03178.15 OAJ24564.1 - 5.7e-65 219.7 0.1 9e-65 219.1 0.1 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAJ24564.1 - 4.2e-08 32.3 0.0 1.2e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Fer2 PF00111.27 OAJ24565.1 - 2.5e-10 40.1 0.4 4.7e-10 39.3 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain N2227 PF07942.12 OAJ24566.1 - 1.4e-87 293.4 0.0 1.9e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein PSII_Pbs27 PF13326.6 OAJ24566.1 - 0.024 14.9 0.1 0.085 13.2 0.0 2.0 3 0 0 3 3 3 0 Photosystem II Pbs27 Tho2 PF11262.8 OAJ24566.1 - 0.59 9.3 2.6 1.1 8.4 1.0 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4602 PF15375.6 OAJ24566.1 - 1.2 9.5 7.2 2.7 8.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) SNase PF00565.17 OAJ24567.1 - 5.8e-45 152.2 0.9 2.9e-17 63.1 0.0 7.2 7 0 0 7 7 7 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OAJ24567.1 - 9.1e-20 70.9 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 OAJ24567.1 - 1.6e-05 25.2 0.0 0.00017 22.0 0.0 2.6 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 OAJ24567.1 - 0.0046 17.0 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) WD40 PF00400.32 OAJ24568.1 - 6.3e-36 121.8 19.4 1.2e-08 35.5 0.5 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24568.1 - 7.2e-14 51.9 0.0 0.0022 18.3 0.0 4.6 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ24568.1 - 0.011 14.7 0.2 5.5 5.8 0.1 3.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 OAJ24568.1 - 0.023 14.4 0.1 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Abhydrolase_1 PF00561.20 OAJ24569.1 - 1.7e-23 83.6 0.0 1.2e-20 74.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ24569.1 - 8.1e-13 48.4 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF836 PF05768.14 OAJ24570.1 - 9.5e-10 38.8 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OAJ24570.1 - 0.015 15.7 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Tfb2 PF03849.14 OAJ24571.1 - 2.1e-28 99.3 0.0 2.5e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 UDPGP PF01704.18 OAJ24572.1 - 2.6e-25 89.0 0.0 8e-15 54.4 0.0 2.3 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase Prp18 PF02840.15 OAJ24573.1 - 3.2e-61 205.6 0.0 5.2e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 OAJ24573.1 - 1.6e-11 43.5 4.4 3.9e-11 42.3 4.4 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like RabGAP-TBC PF00566.18 OAJ24578.1 - 2.4e-17 63.3 0.0 4.6e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phage_Cox PF10743.9 OAJ24579.1 - 0.015 15.3 0.0 14 5.8 0.0 4.0 3 1 1 5 5 5 0 Regulatory phage protein cox RIFIN PF02009.16 OAJ24580.1 - 0.00067 19.7 0.2 0.42 10.5 0.0 2.1 2 0 0 2 2 2 2 Rifin DUF2749 PF10907.8 OAJ24580.1 - 0.0087 16.2 0.7 0.58 10.4 0.0 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2749) DUF2755 PF10954.8 OAJ24580.1 - 0.036 14.0 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Saf_2TM PF18303.1 OAJ24580.1 - 0.044 13.4 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4381 PF14316.6 OAJ24580.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Stevor PF17410.2 OAJ24580.1 - 3.2 7.2 3.3 6.7 6.2 3.3 1.4 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame C2 PF00168.30 OAJ24581.1 - 1.9e-12 47.4 0.0 5.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain DUF4597 PF15366.6 OAJ24581.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Bac_luciferase PF00296.20 OAJ24582.1 - 1.8e-59 201.7 0.6 2.5e-59 201.3 0.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF5362 PF17319.2 OAJ24583.1 - 0.077 12.8 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5362) Staphylcoagulse PF04022.12 OAJ24584.1 - 0.023 14.2 0.1 0.062 12.8 0.1 1.7 1 0 0 1 1 1 0 Staphylocoagulase repeat Ras PF00071.22 OAJ24585.1 - 1.4e-44 151.6 0.0 6e-42 143.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAJ24585.1 - 1.1e-30 106.4 0.0 1.8e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ24585.1 - 2e-11 43.7 0.0 3.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ24585.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ24585.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ24585.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAJ24585.1 - 0.19 11.6 0.0 0.86 9.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase cNMP_binding PF00027.29 OAJ24586.1 - 2.3e-37 126.9 0.1 5.8e-19 68.0 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAJ24586.1 - 2.3e-12 46.4 0.2 4.2e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2722 PF10846.8 OAJ24586.1 - 0.00034 19.7 6.9 0.00047 19.2 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 OAJ24586.1 - 0.0024 17.9 7.9 0.0034 17.5 7.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ24586.1 - 0.0068 16.0 14.1 0.01 15.5 14.1 1.2 1 0 0 1 1 1 1 Spt20 family SEFIR PF08357.11 OAJ24586.1 - 0.2 11.9 1.5 34 4.7 2.9 2.2 2 0 0 2 2 2 0 SEFIR domain UPF0560 PF10577.9 OAJ24586.1 - 0.75 8.2 5.4 1 7.8 5.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Activator_LAG-3 PF11498.8 OAJ24586.1 - 6.2 5.7 28.4 11 4.8 28.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 S4 PF01479.25 OAJ24587.1 - 1.1e-12 47.5 0.0 1.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 OAJ24587.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 S4 domain Plasmodium_Vir PF05795.11 OAJ24587.1 - 0.85 9.0 4.0 0.52 9.7 2.1 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein GREB1 PF15782.5 OAJ24587.1 - 2.3 5.2 3.2 2.8 4.9 3.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spore_coat_CotO PF14153.6 OAJ24587.1 - 3.5 7.5 10.0 5.5 6.9 10.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF3856 PF12968.7 OAJ24588.1 - 0.0089 16.1 1.6 5.2 7.1 0.2 3.3 3 0 0 3 3 3 2 Domain of Unknown Function (DUF3856) HTH_Mga PF08280.11 OAJ24588.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_14 PF13428.6 OAJ24588.1 - 2.6 9.1 5.6 25 6.0 0.9 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ24588.1 - 3.7 7.5 14.2 11 6.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 OAJ24589.1 - 3.9e-07 30.6 2.9 0.11 13.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ24589.1 - 0.032 14.7 0.2 0.27 11.8 0.3 2.2 2 0 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 OAJ24589.1 - 0.18 12.1 0.0 1.7 9.0 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CRT10 PF08728.10 OAJ24589.1 - 0.3 9.2 0.0 0.4 8.8 0.0 1.1 1 0 0 1 1 1 0 CRT10 PARP PF00644.20 OAJ24590.1 - 0.00026 20.7 0.7 0.0019 17.8 0.7 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pkinase PF00069.25 OAJ24591.1 - 6.7e-22 78.1 0.1 4.2e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24591.1 - 3e-09 36.6 0.8 2.9e-07 30.0 0.8 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 OAJ24592.1 - 3.8e-40 135.1 12.4 5.2e-07 30.3 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24592.1 - 1.2e-13 51.2 0.0 0.00075 19.8 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAJ24592.1 - 0.00058 18.5 0.0 0.005 15.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 OAJ24592.1 - 0.0015 17.9 0.0 0.042 13.2 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 OAJ24592.1 - 0.0044 16.0 0.1 0.19 10.7 0.0 3.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OAJ24592.1 - 0.031 12.6 0.0 0.071 11.4 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 OAJ24592.1 - 0.031 12.9 0.2 13 4.3 0.1 3.5 1 1 2 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 OAJ24592.1 - 0.036 14.0 1.3 7.2 6.7 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 OAJ24592.1 - 0.093 13.3 3.3 1.1 9.9 0.5 3.7 3 1 0 3 3 3 0 PQQ-like domain SH3_1 PF00018.28 OAJ24593.1 - 5e-14 51.6 0.2 1e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 OAJ24593.1 - 3.8e-13 49.8 0.0 7.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 OAJ24593.1 - 8.5e-11 41.5 0.1 1.7e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ24593.1 - 6.8e-08 32.1 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 OAJ24593.1 - 1.7e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ24593.1 - 5.3e-06 26.8 0.1 1.2e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 OAJ24593.1 - 0.0005 20.3 0.2 0.00092 19.4 0.2 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Cwf_Cwc_15 PF04889.12 OAJ24594.1 - 0.1 12.3 13.0 0.24 11.1 13.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAJ24594.1 - 0.17 12.1 11.2 0.42 10.8 11.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 OAJ24594.1 - 0.26 10.6 12.0 0.43 9.8 12.0 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OAJ24594.1 - 1.1 9.0 6.6 2.9 7.6 6.6 1.8 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 OAJ24594.1 - 2 8.0 7.6 3.3 7.2 7.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 OAJ24594.1 - 2.3 6.3 10.2 3.5 5.7 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 OAJ24594.1 - 3.6 7.6 6.5 8.5 6.4 6.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 OAJ24594.1 - 3.9 8.2 12.9 13 6.6 12.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Gtr1_RagA PF04670.12 OAJ24595.1 - 1.3e-83 279.9 0.0 2e-83 279.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ24595.1 - 3.9e-07 30.3 0.0 9.4e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ24595.1 - 6e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAJ24595.1 - 0.0002 21.0 0.1 0.00043 19.9 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.21 OAJ24595.1 - 0.00039 19.9 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OAJ24595.1 - 0.013 15.3 0.9 0.047 13.4 0.4 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAJ24595.1 - 0.039 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 OAJ24595.1 - 0.085 12.0 0.4 12 5.0 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 OAJ24595.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TPR_MLP1_2 PF07926.12 OAJ24596.1 - 5.4e-05 23.3 39.8 0.019 15.0 6.9 3.0 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein HALZ PF02183.18 OAJ24596.1 - 0.0012 19.0 0.4 0.0012 19.0 0.4 4.7 3 2 1 4 4 4 1 Homeobox associated leucine zipper Mt_ATP-synt_B PF05405.14 OAJ24596.1 - 0.0094 15.6 9.9 0.0094 15.6 9.9 2.1 1 1 1 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Erythro-docking PF09277.11 OAJ24596.1 - 0.043 13.7 0.5 0.12 12.3 0.5 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking CENP-F_leu_zip PF10473.9 OAJ24596.1 - 0.06 13.4 30.9 0.57 10.2 8.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CcdB PF01845.17 OAJ24596.1 - 0.16 12.2 1.9 1 9.6 0.1 2.7 2 1 0 3 3 3 0 CcdB protein FUSC PF04632.12 OAJ24596.1 - 0.23 9.9 15.5 0.28 9.7 15.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ApoO PF09769.9 OAJ24596.1 - 0.56 10.2 6.0 0.36 10.8 0.9 2.5 1 1 1 2 2 2 0 Apolipoprotein O DASH_Dam1 PF08653.10 OAJ24596.1 - 0.68 9.8 4.8 1.9 8.3 0.1 3.4 2 1 2 4 4 4 0 DASH complex subunit Dam1 COG5 PF10392.9 OAJ24596.1 - 0.72 10.0 11.8 0.14 12.4 6.3 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 FAM184 PF15665.5 OAJ24596.1 - 0.78 9.5 29.2 1.4 8.6 29.2 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B ATPase PF06745.13 OAJ24596.1 - 1.1 8.6 6.6 0.1 11.9 0.8 1.9 2 0 0 2 2 2 0 KaiC Spc7 PF08317.11 OAJ24596.1 - 1.1 8.0 32.3 0.051 12.5 23.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAJ24596.1 - 1.2 8.4 22.3 3.4 6.9 22.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1690 PF07956.11 OAJ24596.1 - 1.7 9.0 28.7 0.092 13.2 14.7 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) YabA PF06156.13 OAJ24596.1 - 2 9.1 21.1 2.2 9.0 4.0 2.8 1 1 2 3 3 3 0 Initiation control protein YabA DUF4472 PF14739.6 OAJ24596.1 - 2.3 9.0 27.3 5.6 7.8 13.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) GAS PF13851.6 OAJ24596.1 - 2.9 7.2 28.6 1.5 8.1 19.3 2.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 OAJ24596.1 - 3.1 8.3 37.9 3.7 8.1 12.6 3.9 1 1 2 3 3 3 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 OAJ24596.1 - 4.4 7.5 35.8 0.43 10.8 12.3 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MRP-S27 PF10037.9 OAJ24596.1 - 6.7 5.5 19.7 7.1 5.4 19.0 1.3 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 TBD PF12845.7 OAJ24596.1 - 7.7 6.5 13.6 0.37 10.7 1.4 2.9 3 0 0 3 3 3 0 TBD domain PIN_8 PF18476.1 OAJ24596.1 - 8.2 6.2 13.4 6.3 6.6 11.9 1.5 1 1 0 1 1 1 0 PIN like domain KIP1 PF07765.12 OAJ24596.1 - 9.2 6.5 10.5 1.7 8.9 2.9 2.5 2 1 0 2 2 2 0 KIP1-like protein Ank_2 PF12796.7 OAJ24597.1 - 1.7e-15 57.4 0.7 3.4e-06 27.6 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ24597.1 - 8.9e-13 48.5 4.2 5.7e-05 23.6 0.8 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ24597.1 - 6.7e-10 39.0 1.2 0.0002 21.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ24597.1 - 8.4e-10 38.0 1.9 0.0084 16.6 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OAJ24597.1 - 1.3e-09 38.0 12.8 1.9e-05 24.9 1.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat TERB2 PF15101.6 OAJ24597.1 - 0.15 12.1 5.8 0.34 10.9 5.8 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2368 PF10166.9 OAJ24597.1 - 0.87 9.2 7.3 2.7 7.6 5.2 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) RSF PF14876.6 OAJ24597.1 - 1 8.2 5.0 1.6 7.6 5.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Spt20 PF12090.8 OAJ24597.1 - 1.4 8.5 20.4 0.35 10.4 17.0 1.7 2 0 0 2 2 2 0 Spt20 family EPL1 PF10513.9 OAJ24597.1 - 2.4 8.5 7.0 0.29 11.5 2.1 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Roughex PF06020.11 OAJ24597.1 - 3 6.8 7.2 5.7 5.9 7.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein UQ_con PF00179.26 OAJ24598.1 - 2.2e-39 134.3 0.0 2.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ24598.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain MFS_1 PF07690.16 OAJ24599.1 - 1.2e-20 73.8 38.3 1.9e-13 50.1 22.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAJ24599.1 - 1.1e-11 44.7 5.2 1.1e-11 44.7 5.2 2.4 2 1 0 2 2 2 1 Nodulin-like zf-CCHH PF10283.9 OAJ24599.1 - 0.066 13.2 1.5 0.12 12.4 1.5 1.4 1 0 0 1 1 1 0 PBZ domain 4HBT PF03061.22 OAJ24600.1 - 2.4e-08 34.2 0.0 3.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAJ24600.1 - 0.0037 17.5 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ABC2_membrane PF01061.24 OAJ24606.1 - 1.2e-56 191.4 44.1 4.5e-31 107.9 23.9 3.0 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 OAJ24606.1 - 1.6e-29 101.7 8.8 4.3e-28 97.0 0.1 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 OAJ24606.1 - 8.5e-19 68.4 0.0 1.7e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAJ24606.1 - 2.7e-06 27.4 0.0 5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OAJ24606.1 - 2.7e-05 24.6 0.1 6.4e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAJ24606.1 - 0.00098 18.8 0.1 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAJ24606.1 - 0.016 15.0 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAJ24606.1 - 0.027 14.7 0.2 0.066 13.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OAJ24606.1 - 0.028 14.4 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAJ24606.1 - 0.034 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 OAJ24606.1 - 0.064 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ24606.1 - 0.082 12.7 0.7 0.32 10.8 0.1 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain cobW PF02492.19 OAJ24606.1 - 0.16 11.5 0.3 0.28 10.8 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L31 PF01197.18 OAJ24608.1 - 0.074 13.3 0.4 0.17 12.2 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 PTPRCAP PF15713.5 OAJ24608.1 - 0.3 11.4 12.5 0.56 10.5 12.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 OAJ24608.1 - 0.48 10.5 13.6 0.13 12.3 3.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 OAJ24608.1 - 1.7 6.8 8.3 2.2 6.5 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zinc_ribbon_15 PF17032.5 OAJ24608.1 - 2.4 9.0 6.0 3.8 8.3 0.6 2.6 1 1 1 2 2 2 0 zinc-ribbon family Cytochrom_c3_2 PF14537.6 OAJ24608.1 - 8.4 6.9 12.4 0.24 11.9 3.4 2.5 2 0 0 2 2 2 0 Cytochrome c3 DDE_1 PF03184.19 OAJ24609.1 - 2.3e-19 69.7 0.0 4.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_11 PF13086.6 OAJ24609.1 - 2.8 7.7 16.2 5.5 6.7 16.2 1.6 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 OAJ24609.1 - 7 5.0 34.0 9.4 4.6 34.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_13 PF13166.6 OAJ24609.1 - 8.6 4.9 19.7 12 4.4 19.7 1.2 1 0 0 1 1 1 0 AAA domain TAF4 PF05236.14 OAJ24610.1 - 0.00046 20.0 21.3 0.00054 19.8 21.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family EPL1 PF10513.9 OAJ24610.1 - 0.00061 20.2 11.2 0.00073 19.9 11.2 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like TFIIA PF03153.13 OAJ24610.1 - 0.00098 19.2 25.5 0.001 19.1 25.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OAJ24610.1 - 0.0044 15.9 16.6 0.0039 16.0 16.6 1.1 1 0 0 1 1 1 1 Presenilin NPR3 PF03666.13 OAJ24610.1 - 0.0067 15.3 14.6 0.0058 15.5 14.6 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 MMR1 PF08505.10 OAJ24610.1 - 0.017 15.4 13.5 0.018 15.4 13.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DDHD PF02862.17 OAJ24610.1 - 0.024 14.8 9.7 0.029 14.6 9.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF3807 PF12720.7 OAJ24610.1 - 0.041 14.2 26.9 0.069 13.4 26.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2514 PF10721.9 OAJ24610.1 - 0.078 13.0 21.8 0.13 12.3 21.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) SAPS PF04499.15 OAJ24610.1 - 0.086 11.6 10.7 0.089 11.6 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Bud13 PF09736.9 OAJ24610.1 - 0.093 13.1 23.1 0.16 12.4 23.1 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peptidase_S64 PF08192.11 OAJ24610.1 - 0.096 11.2 12.2 0.094 11.2 12.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2151 PF10221.9 OAJ24610.1 - 0.15 10.6 9.5 0.16 10.5 9.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF3295 PF11702.8 OAJ24610.1 - 0.16 11.3 20.3 0.18 11.1 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PAT1 PF09770.9 OAJ24610.1 - 0.18 10.0 25.2 0.2 9.9 25.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 OAJ24610.1 - 0.26 11.5 17.0 0.47 10.6 17.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 OAJ24610.1 - 0.3 10.5 9.0 0.29 10.5 9.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PTPRCAP PF15713.5 OAJ24610.1 - 0.37 11.1 24.5 0.045 14.1 20.8 1.5 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated Hid1 PF12722.7 OAJ24610.1 - 0.38 8.8 15.2 0.4 8.8 15.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 OAJ24610.1 - 0.4 10.0 19.8 0.48 9.7 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tim54 PF11711.8 OAJ24610.1 - 0.43 9.3 18.5 0.54 9.0 18.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spt20 PF12090.8 OAJ24610.1 - 0.44 10.1 44.1 0.63 9.6 44.1 1.2 1 0 0 1 1 1 0 Spt20 family CSRNP_N PF16019.5 OAJ24610.1 - 0.65 9.9 16.7 1 9.2 16.7 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Hydin_ADK PF17213.3 OAJ24610.1 - 0.73 10.1 15.7 0.95 9.7 15.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MDM10 PF12519.8 OAJ24610.1 - 0.74 8.6 16.1 0.87 8.4 16.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SRP-alpha_N PF04086.13 OAJ24610.1 - 0.76 9.7 21.7 1.1 9.2 21.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 OAJ24610.1 - 0.81 8.8 6.9 0.81 8.8 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter IER PF05760.12 OAJ24610.1 - 1.1 9.6 18.3 1.2 9.3 18.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) LAP1C PF05609.12 OAJ24610.1 - 1.5 7.8 17.7 1.7 7.6 17.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peroxin-3 PF04882.12 OAJ24610.1 - 2.3 7.1 16.1 2.3 7.1 16.1 1.2 1 0 0 1 1 1 0 Peroxin-3 Sporozoite_P67 PF05642.11 OAJ24610.1 - 2.5 6.1 14.7 3.2 5.7 14.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UPF0565 PF10561.9 OAJ24610.1 - 2.7 7.1 8.0 3 7.0 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF4551 PF15087.6 OAJ24610.1 - 3 6.6 15.5 3.3 6.4 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SLC12 PF03522.15 OAJ24610.1 - 3.5 6.6 21.7 4.6 6.2 21.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 OAJ24610.1 - 4.1 4.4 18.7 4.7 4.2 18.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AF-4 PF05110.13 OAJ24610.1 - 6 4.8 28.4 7.1 4.6 28.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4746 PF15928.5 OAJ24610.1 - 6.2 6.2 19.7 8.8 5.7 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2126 PF09899.9 OAJ24610.1 - 7.3 4.5 15.0 8.6 4.3 15.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 OAJ24610.1 - 8.3 5.8 24.9 11 5.4 24.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIF_alpha PF05793.12 OAJ24610.1 - 9.9 4.6 29.1 16 3.9 29.1 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Titin_Z PF09042.11 OAJ24611.1 - 0.015 15.2 3.4 0.043 13.8 3.4 1.9 1 1 0 1 1 1 0 Titin Z Na_trans_assoc PF06512.13 OAJ24611.1 - 0.043 14.1 2.6 0.057 13.7 2.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated 2OG-FeII_Oxy_5 PF13759.6 OAJ24612.1 - 0.074 13.5 0.3 5 7.6 0.0 2.9 3 0 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase RRF PF01765.19 OAJ24613.1 - 0.0097 15.9 0.2 0.013 15.5 0.2 1.3 1 1 0 1 1 1 1 Ribosome recycling factor Calc_CGRP_IAPP PF00214.19 OAJ24613.1 - 0.043 14.2 0.9 0.049 14.0 0.9 1.3 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family CpXC PF14353.6 OAJ24613.1 - 0.085 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 CpXC protein DUF1192 PF06698.11 OAJ24613.1 - 9.6 6.3 10.9 0.22 11.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) F-box-like PF12937.7 OAJ24614.1 - 7.4e-05 22.6 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 OAJ24615.1 - 0.013 15.4 1.3 0.022 14.7 0.2 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAJ24615.1 - 0.24 11.3 1.5 0.54 10.2 0.3 2.2 2 0 0 2 2 2 0 F-box domain ResB PF05140.14 OAJ24617.1 - 0.066 11.9 0.1 0.066 11.9 0.1 1.6 2 0 0 2 2 2 0 ResB-like family MSA-2c PF12238.8 OAJ24617.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c TPR_2 PF07719.17 OAJ24618.1 - 4.3e-25 85.8 18.0 0.0004 20.3 0.2 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ24618.1 - 1.1e-22 78.9 12.9 0.0051 16.6 0.1 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat DnaJ PF00226.31 OAJ24618.1 - 3.4e-21 75.1 1.6 7.2e-21 74.1 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 OAJ24618.1 - 3.1e-17 62.8 20.9 0.00046 20.6 7.1 6.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ24618.1 - 8.3e-16 58.4 23.7 0.00012 22.6 1.1 6.5 4 3 2 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ24618.1 - 8.9e-15 54.8 16.7 1.4e-05 25.3 0.1 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ24618.1 - 1.2e-13 50.7 21.1 0.033 15.0 0.1 6.7 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ24618.1 - 1.2e-12 46.9 16.2 0.02 15.1 0.1 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ24618.1 - 7.3e-11 42.2 9.7 0.02 15.1 1.3 4.4 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ24618.1 - 5.1e-09 36.1 8.0 0.0085 16.2 0.4 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ24618.1 - 4e-07 29.6 4.2 0.33 11.1 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ24618.1 - 1.1e-06 28.2 22.6 0.0011 18.6 1.7 6.5 5 2 2 7 7 7 2 TPR repeat TPR_17 PF13431.6 OAJ24618.1 - 7.3e-06 26.0 7.5 1.1 9.8 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ24618.1 - 3.2e-05 23.5 8.9 0.01 15.2 0.8 3.4 1 1 1 3 3 3 2 MalT-like TPR region Fis1_TPR_C PF14853.6 OAJ24618.1 - 8e-05 22.6 10.6 0.01 15.9 0.2 4.8 4 1 1 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OAJ24618.1 - 0.00021 21.7 19.8 0.54 11.0 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF1840 PF08895.11 OAJ24618.1 - 0.021 15.1 7.2 0.09 13.1 1.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) TPR_4 PF07721.14 OAJ24618.1 - 0.029 15.0 4.6 0.52 11.1 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GATase1_like PF07090.11 OAJ24618.1 - 0.078 12.4 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative glutamine amidotransferase SMBP PF16785.5 OAJ24618.1 - 0.11 12.8 13.6 0.29 11.4 1.3 4.6 4 1 1 5 5 4 0 Small metal-binding protein PTN_MK_C PF01091.18 OAJ24618.1 - 0.24 11.8 1.8 0.36 11.2 0.2 2.1 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain DUF3856 PF12968.7 OAJ24618.1 - 0.3 11.2 3.9 2.5 8.2 0.3 3.2 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPM_phosphatase PF04536.14 OAJ24618.1 - 0.32 11.2 3.7 56 3.9 0.0 3.6 2 1 1 3 3 3 0 TPM domain ANAPC5 PF12862.7 OAJ24618.1 - 1.8 8.7 4.3 25 5.0 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 OAJ24618.1 - 2.1 8.4 17.4 7.8 6.6 0.1 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Glyco_hydro_45 PF02015.16 OAJ24619.1 - 9.1e-16 58.4 0.3 1.5e-15 57.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 PUF PF00806.19 OAJ24620.1 - 3.4e-11 42.2 0.0 0.02 14.5 0.0 5.9 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Bot1p PF12298.8 OAJ24621.1 - 4e-23 82.4 0.0 4e-23 82.4 0.0 1.9 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 OAJ24621.1 - 0.05 13.8 0.0 0.05 13.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 Macoilin PF09726.9 OAJ24621.1 - 0.38 9.3 9.3 0.0052 15.4 0.9 1.9 2 0 0 2 2 2 0 Macoilin family Rrp44_CSD1 PF17216.3 OAJ24622.1 - 0.009 15.7 4.8 0.011 15.5 4.8 1.1 1 0 0 1 1 1 1 Rrp44-like cold shock domain Lin-8 PF03353.15 OAJ24622.1 - 0.062 12.9 2.1 0.062 12.9 2.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pep1_7 PF17232.2 OAJ24622.1 - 0.66 10.5 8.9 1.4 9.4 8.7 1.7 1 1 0 1 1 1 0 Elicitor peptide 1-7 DNA_pol_phi PF04931.13 OAJ24622.1 - 0.9 7.6 5.4 0.88 7.6 5.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi SR-25 PF10500.9 OAJ24622.1 - 3.2 7.3 19.5 3.5 7.2 19.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PI3K_1B_p101 PF10486.9 OAJ24622.1 - 6.9 4.3 12.2 6.5 4.4 12.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cwf_Cwc_15 PF04889.12 OAJ24622.1 - 7.2 6.3 12.0 8.1 6.1 12.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_10 PF13374.6 OAJ24623.1 - 0.003 17.4 1.8 0.077 12.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ24623.1 - 0.016 15.5 1.2 0.082 13.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ24623.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF3584 PF12128.8 OAJ24624.1 - 0.00015 19.5 0.7 0.00017 19.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4337 PF14235.6 OAJ24624.1 - 0.0066 16.6 0.7 0.011 15.9 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) DUF883 PF05957.13 OAJ24624.1 - 0.0086 16.6 8.2 0.0086 16.6 8.2 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) RRF PF01765.19 OAJ24624.1 - 0.018 15.0 4.6 0.026 14.5 4.6 1.2 1 0 0 1 1 1 0 Ribosome recycling factor FPN1 PF06963.12 OAJ24624.1 - 0.024 13.2 0.1 0.031 12.8 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TMPIT PF07851.13 OAJ24624.1 - 0.032 13.5 0.4 0.042 13.1 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 OAJ24624.1 - 0.034 14.4 6.1 0.048 13.9 6.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 OAJ24624.1 - 0.042 14.3 4.0 0.059 13.8 4.0 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SET PF00856.28 OAJ24624.1 - 0.076 13.4 0.2 0.086 13.2 0.2 1.2 1 0 0 1 1 1 0 SET domain Borrelia_P83 PF05262.11 OAJ24624.1 - 0.13 10.8 5.2 0.16 10.4 5.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3810 PF12725.7 OAJ24624.1 - 0.17 11.2 0.3 0.23 10.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ATP-synt_B PF00430.18 OAJ24624.1 - 0.45 10.6 10.0 0.83 9.8 10.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4366 PF14283.6 OAJ24624.1 - 0.57 10.2 5.4 0.056 13.5 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Peptidase_S49_N PF08496.10 OAJ24624.1 - 0.84 9.7 5.9 1.4 8.9 5.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal XhlA PF10779.9 OAJ24624.1 - 8.5 6.7 6.8 6.2 7.1 4.7 1.9 1 1 1 2 2 2 0 Haemolysin XhlA Leu_leader PF08054.11 OAJ24625.1 - 0.0063 16.1 0.8 0.017 14.7 0.8 1.7 1 0 0 1 1 1 1 Leucine operon leader peptide Zw10 PF06248.13 OAJ24625.1 - 0.032 12.8 0.9 0.55 8.7 0.0 2.6 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 tRNA-synt_1b PF00579.25 OAJ24627.1 - 4.4e-19 68.9 0.0 2.2e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Oxysterol_BP PF01237.18 OAJ24628.1 - 3e-44 151.4 1.3 2.8e-27 95.5 1.1 3.9 2 1 0 2 2 2 2 Oxysterol-binding protein 2OG-FeII_Oxy_3 PF13640.6 OAJ24629.1 - 0.089 13.7 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BLIP PF07467.11 OAJ24629.1 - 0.15 12.7 0.1 0.62 10.7 0.1 1.9 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) Sugar_tr PF00083.24 OAJ24630.1 - 1.5e-40 139.5 12.8 2.8e-40 138.5 12.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ24630.1 - 5.7e-25 88.0 26.6 2.8e-12 46.3 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1115 PF06544.12 OAJ24631.1 - 3.4e-06 27.2 0.0 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) SR-25 PF10500.9 OAJ24631.1 - 7.3 6.1 9.1 11 5.5 1.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Elong_Iki1 PF10483.9 OAJ24632.1 - 2e-12 47.3 0.4 1.4e-06 28.0 0.2 2.9 2 1 0 2 2 2 2 Elongator subunit Iki1 Acyl-CoA_dh_N PF02771.16 OAJ24633.1 - 7.6e-29 100.7 0.1 1.4e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAJ24633.1 - 1.4e-23 83.8 0.0 2.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ24633.1 - 1.9e-22 79.3 0.0 3.6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ24633.1 - 0.00031 21.0 0.3 0.00031 21.0 0.3 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 OAJ24634.1 - 7.2e-45 152.9 4.8 7.2e-45 152.9 4.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ24634.1 - 2.6e-28 98.9 0.0 7.8e-28 97.4 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ24634.1 - 4e-24 84.7 0.1 7e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ24634.1 - 8.8e-22 77.8 2.2 8.8e-22 77.8 2.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Iso_dh PF00180.20 OAJ24635.1 - 3.4e-78 263.2 0.0 5e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTH2 PF01981.16 OAJ24636.1 - 1.1e-08 35.3 0.5 3.6e-08 33.7 0.5 1.8 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4527 PF15030.6 OAJ24636.1 - 0.031 13.7 0.6 0.068 12.6 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) DUF1077 PF06417.12 OAJ24637.1 - 5.1e-47 158.7 0.6 7.1e-47 158.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF5589 PF17672.1 OAJ24637.1 - 0.027 14.4 0.0 0.49 10.3 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5589) COesterase PF00135.28 OAJ24639.1 - 1.5e-72 245.1 0.2 2.4e-63 214.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ24639.1 - 6.9e-05 22.8 0.1 0.0002 21.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.22 OAJ24640.1 - 3.4e-16 60.1 0.1 5e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pro_Al_protease PF02983.14 OAJ24640.1 - 0.098 12.7 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain TFIIA PF03153.13 OAJ24641.1 - 0.029 14.4 26.3 0.014 15.5 17.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TetR_C_14 PF17754.1 OAJ24641.1 - 0.067 13.1 0.3 17 5.4 0.1 2.5 2 0 0 2 2 2 0 MftR C-terminal domain TMEM51 PF15345.6 OAJ24641.1 - 0.92 9.3 9.8 1.5 8.6 9.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.8 OAJ24641.1 - 2 7.9 28.3 0.57 9.7 17.3 2.3 2 0 0 2 2 2 0 Spt20 family Ribonuclease_T2 PF00445.18 OAJ24642.1 - 2.2e-34 119.3 0.1 2.8e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Peptidase_C54 PF03416.19 OAJ24643.1 - 2.5e-99 332.2 0.0 3.9e-99 331.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 CBM_26 PF16824.5 OAJ24645.1 - 0.13 12.4 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 C-terminal carbohydrate-binding module AAA_2 PF07724.14 OAJ24646.1 - 3.3e-43 147.8 0.0 4.2e-40 137.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAJ24646.1 - 1.2e-28 99.0 0.4 1.2e-28 99.0 0.4 2.5 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAJ24646.1 - 2.6e-26 91.5 0.9 1.2e-25 89.4 0.1 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAJ24646.1 - 1.7e-19 70.5 0.0 5.5e-10 39.8 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ24646.1 - 4.1e-11 42.9 0.1 1.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ24646.1 - 7.6e-11 42.2 0.0 9.5e-06 25.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ24646.1 - 4.3e-08 33.7 10.1 0.00016 22.1 0.4 4.7 3 2 0 3 3 2 2 AAA ATPase domain TniB PF05621.11 OAJ24646.1 - 2.5e-06 27.0 0.0 0.00022 20.7 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 OAJ24646.1 - 4.4e-06 26.3 0.2 0.03 13.8 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 OAJ24646.1 - 2.5e-05 24.3 0.2 0.0074 16.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OAJ24646.1 - 3.8e-05 23.5 0.0 0.07 12.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OAJ24646.1 - 7.2e-05 22.8 0.1 0.55 10.1 0.0 3.3 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 OAJ24646.1 - 0.00011 21.7 0.0 0.26 10.6 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAJ24646.1 - 0.00013 21.3 0.0 0.071 12.4 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 OAJ24646.1 - 0.00019 21.5 0.0 0.39 10.7 0.0 3.5 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit DUF853 PF05872.12 OAJ24646.1 - 0.00042 19.0 1.6 0.22 10.0 0.0 2.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 OAJ24646.1 - 0.0005 20.4 9.1 0.097 12.9 0.1 5.2 4 3 0 4 4 3 1 AAA domain NACHT PF05729.12 OAJ24646.1 - 0.0005 20.0 0.2 0.8 9.6 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_6 PF12774.7 OAJ24646.1 - 0.00051 19.1 0.1 0.042 12.8 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 OAJ24646.1 - 0.00059 20.4 0.0 1.1 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 OAJ24646.1 - 0.00073 18.6 0.0 0.69 8.8 0.0 2.8 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 OAJ24646.1 - 0.0029 17.6 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAJ24646.1 - 0.0038 17.5 4.8 1.2 9.3 0.0 3.8 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 OAJ24646.1 - 0.0042 16.9 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 OAJ24646.1 - 0.0048 16.0 0.0 0.062 12.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 OAJ24646.1 - 0.0048 17.3 0.1 3.5 8.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.6 OAJ24646.1 - 0.005 17.2 1.7 1 9.7 0.2 3.3 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ24646.1 - 0.0055 16.0 3.9 0.072 12.3 0.0 2.8 4 0 0 4 4 2 1 TIP49 P-loop domain CENP-F_leu_zip PF10473.9 OAJ24646.1 - 0.0056 16.7 10.6 0.013 15.6 10.6 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Torsin PF06309.11 OAJ24646.1 - 0.0063 16.6 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 Torsin SRP54 PF00448.22 OAJ24646.1 - 0.0081 15.8 0.2 2.9 7.5 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OAJ24646.1 - 0.0098 16.1 1.4 7.9 6.6 0.1 3.6 3 0 0 3 3 3 0 AAA domain T3SS_needle_E PF08988.10 OAJ24646.1 - 0.017 15.2 2.1 0.42 10.8 0.9 3.4 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle AAA_24 PF13479.6 OAJ24646.1 - 0.039 13.7 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 OAJ24646.1 - 0.059 12.9 0.1 0.059 12.9 0.1 3.4 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain AAA_3 PF07726.11 OAJ24646.1 - 0.063 13.1 0.1 0.61 10.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ24646.1 - 0.065 12.4 0.6 7.5 5.6 0.1 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 OAJ24646.1 - 0.13 11.7 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 OAJ24646.1 - 0.49 10.4 5.3 5.6 7.0 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain RasGAP PF00616.19 OAJ24647.1 - 2.2e-18 66.8 0.0 3.1e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 OAJ24647.1 - 5.7e-07 29.8 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain She9_MDM33 PF05546.11 OAJ24652.1 - 2.8e-60 203.5 7.4 2.8e-60 203.5 7.4 1.4 1 1 0 1 1 1 1 She9 / Mdm33 family DUF2207 PF09972.9 OAJ24652.1 - 0.064 12.0 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cauli_VI PF01693.16 OAJ24653.1 - 1.2e-06 28.7 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Nop14 PF04147.12 OAJ24653.1 - 4.7 5.3 10.3 6.6 4.8 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 OAJ24653.1 - 5.1 6.7 7.1 8 6.1 7.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2857 PF11198.8 OAJ24655.1 - 0.014 15.2 0.1 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) TetR_C_27 PF17935.1 OAJ24655.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sipho_Gp157 PF05565.11 OAJ24655.1 - 0.026 14.5 0.6 0.032 14.2 0.6 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 PhaP_Bmeg PF09602.10 OAJ24655.1 - 0.068 13.1 0.1 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SGL PF08450.12 OAJ24656.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region GDC-P PF02347.16 OAJ24657.1 - 7.1e-182 605.0 0.0 4.6e-171 569.4 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAJ24657.1 - 0.0058 15.9 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Pkinase PF00069.25 OAJ24659.1 - 3.1e-49 167.7 0.0 8.9e-49 166.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24659.1 - 3.2e-20 72.5 0.0 1.4e-19 70.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAJ24659.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TIP49 PF06068.13 OAJ24660.1 - 4.7e-150 499.6 0.0 6.3e-150 499.2 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ24660.1 - 6.6e-24 83.8 1.5 3.3e-23 81.6 1.5 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAJ24660.1 - 4.9e-12 46.4 0.7 4e-09 37.0 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ24660.1 - 6.7e-12 45.4 1.6 1.1e-08 34.9 0.1 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ24660.1 - 5e-07 30.3 0.1 1.8e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 OAJ24660.1 - 1.6e-06 27.7 0.3 3e-06 26.7 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OAJ24660.1 - 1.7e-06 28.4 0.1 0.084 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ24660.1 - 7.9e-06 25.9 0.2 0.0038 17.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ24660.1 - 1.3e-05 24.7 0.7 0.00051 19.5 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAJ24660.1 - 1.9e-05 25.0 0.3 0.00016 22.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAJ24660.1 - 4.3e-05 23.3 0.1 0.066 12.9 0.1 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 OAJ24660.1 - 0.0006 19.4 0.3 0.0025 17.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 OAJ24660.1 - 0.00069 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 OAJ24660.1 - 0.00073 20.0 0.1 0.0017 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAJ24660.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 OAJ24660.1 - 0.0021 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OAJ24660.1 - 0.0029 18.2 1.8 0.0043 17.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAJ24660.1 - 0.0047 16.5 0.1 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 OAJ24660.1 - 0.006 16.6 0.0 7.2 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OAJ24660.1 - 0.0068 16.1 0.3 0.17 11.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAJ24660.1 - 0.0072 16.3 0.3 0.018 15.0 0.0 1.8 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ24660.1 - 0.0087 16.2 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ24660.1 - 0.0099 15.7 0.2 0.021 14.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAJ24660.1 - 0.011 15.0 0.3 0.039 13.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAJ24660.1 - 0.012 15.6 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 OAJ24660.1 - 0.017 14.4 0.1 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 OAJ24660.1 - 0.02 15.4 0.1 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAJ24660.1 - 0.02 15.0 0.0 0.99 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PIF1 PF05970.14 OAJ24660.1 - 0.021 14.0 0.6 0.89 8.6 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 OAJ24660.1 - 0.026 14.0 0.1 0.069 12.6 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAJ24660.1 - 0.029 14.6 0.1 0.078 13.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAJ24660.1 - 0.037 14.2 0.2 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 OAJ24660.1 - 0.047 13.6 0.4 0.19 11.6 0.1 2.3 2 1 0 2 2 1 0 NTPase RNA_helicase PF00910.22 OAJ24660.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAJ24660.1 - 0.097 12.4 0.2 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain CDP-OH_P_transf PF01066.21 OAJ24662.1 - 1.4e-12 48.2 0.2 3.4e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Tetraspanin PF00335.20 OAJ24663.1 - 1.9e-06 27.8 0.8 1.9e-06 27.8 0.8 1.9 1 1 1 2 2 2 1 Tetraspanin family Shisa PF13908.6 OAJ24663.1 - 0.00063 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3357 PF11837.8 OAJ24663.1 - 0.062 13.8 0.6 26 5.3 0.0 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF3357) DUF2569 PF10754.9 OAJ24663.1 - 0.25 11.8 7.6 0.15 12.5 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2207 PF09972.9 OAJ24663.1 - 4.3 6.0 4.6 42 2.7 4.7 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4389 PF14333.6 OAJ24663.1 - 6.5 6.8 6.3 9 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) zf-HIT PF04438.16 OAJ24664.1 - 6.7e-09 35.5 10.3 9.5e-09 35.0 10.3 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 OAJ24664.1 - 1.4 9.2 4.9 2.3 8.5 4.9 1.3 1 0 0 1 1 1 0 B-box zinc finger RNA_POL_M_15KD PF02150.16 OAJ24665.1 - 6.5e-13 48.3 4.0 6.5e-13 48.3 4.0 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 OAJ24665.1 - 1.9e-10 40.4 13.6 7.5e-10 38.5 4.1 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 OAJ24665.1 - 0.0017 18.4 8.0 1.2 9.3 0.1 3.9 4 0 0 4 4 4 2 Zinc ribbon domain GFA PF04828.14 OAJ24665.1 - 0.0024 18.2 7.1 0.0089 16.3 0.1 2.7 1 1 2 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme CpXC PF14353.6 OAJ24665.1 - 0.54 10.3 7.1 6.9 6.7 2.2 2.7 1 1 1 2 2 2 0 CpXC protein zf-ISL3 PF14690.6 OAJ24665.1 - 0.55 10.9 5.2 1.6 9.4 0.0 3.0 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 OAJ24665.1 - 1.1 9.3 11.6 6.8 6.8 4.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 OAJ24665.1 - 1.2 8.7 12.6 0.48 10.0 3.8 3.4 3 1 1 4 4 4 0 TFIIB zinc-binding DUF3268 PF11672.8 OAJ24665.1 - 1.4 9.3 6.7 4 7.8 1.7 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain Ribosomal_L31e PF01198.19 OAJ24666.1 - 6.1e-36 122.5 1.8 1.2e-35 121.6 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e Arginosuc_synth PF00764.19 OAJ24667.1 - 3e-157 523.9 0.0 3.6e-157 523.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAJ24667.1 - 0.00016 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OAJ24667.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase LolA PF03548.15 OAJ24667.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA DUF3535 PF12054.8 OAJ24668.1 - 2.4e-104 350.0 0.0 1.4e-102 344.2 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAJ24668.1 - 5.1e-63 212.9 0.0 8.3e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ24668.1 - 3.7e-16 59.4 0.0 9.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAJ24668.1 - 6.6e-13 47.7 31.1 0.045 14.0 0.0 11.2 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.6 OAJ24668.1 - 0.011 16.3 29.1 5.6 7.6 0.0 11.4 13 0 0 13 13 13 0 HEAT-like repeat HEAT_2 PF13646.6 OAJ24668.1 - 0.012 16.0 21.7 9 6.8 0.1 8.8 10 0 0 10 10 10 0 HEAT repeats RIX1 PF08167.12 OAJ24668.1 - 0.023 14.4 0.6 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 OAJ24668.1 - 0.034 14.7 0.0 0.68 10.6 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region SUIM_assoc PF16619.5 OAJ24668.1 - 0.21 11.7 1.4 1.1 9.4 1.4 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Smr PF01713.21 OAJ24669.1 - 3.2e-08 33.8 0.0 3.5e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Smr domain ANAPC9 PF12856.7 OAJ24669.1 - 0.4 10.9 2.4 1.1 9.5 2.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 DNA_pol_phi PF04931.13 OAJ24669.1 - 0.43 8.6 2.5 0.82 7.7 2.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi ATP13 PF12921.7 OAJ24674.1 - 0.038 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF5407 PF17401.2 OAJ24674.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) Ribosomal_L14e PF01929.17 OAJ24675.1 - 3.1e-27 94.9 0.7 4.7e-27 94.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAJ24675.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 KOW motif Ribosomal_L44 PF00935.19 OAJ24676.1 - 4.8e-36 123.1 12.7 7.1e-36 122.5 12.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Dynamin_N PF00350.23 OAJ24680.1 - 3.8e-17 62.8 0.0 9.9e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAJ24680.1 - 4.5e-12 46.0 0.0 1.6e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ24680.1 - 4.3e-08 32.9 0.3 2.3e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ24680.1 - 0.00058 19.8 1.3 0.88 9.5 0.1 3.0 2 1 0 2 2 2 2 RsgA GTPase IIGP PF05049.13 OAJ24680.1 - 0.0042 16.2 0.2 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) cobW PF02492.19 OAJ24680.1 - 0.012 15.2 0.1 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 OAJ24680.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OAJ24680.1 - 0.031 14.5 0.2 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TPR_MLP1_2 PF07926.12 OAJ24680.1 - 0.038 14.1 6.7 0.03 14.4 3.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_29 PF13555.6 OAJ24680.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 OAJ24680.1 - 0.1 12.1 0.2 6.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NPV_P10 PF05531.12 OAJ24680.1 - 0.29 11.6 6.9 27 5.3 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein AAA_16 PF13191.6 OAJ24680.1 - 1 9.7 4.6 0.87 9.9 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 OAJ24681.1 - 2.9e-40 138.3 0.0 1.3e-26 93.6 0.0 4.2 3 2 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24681.1 - 4e-23 82.0 0.0 1.6e-19 70.3 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ24681.1 - 0.0011 18.9 0.0 0.15 12.0 0.0 2.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ24681.1 - 0.032 13.6 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like PBP1_TM PF14812.6 OAJ24681.1 - 3.6 8.0 17.6 17 5.9 6.6 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.6 OAJ24682.1 - 1.9e-23 82.9 0.0 2.7e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ24682.1 - 6.1e-07 29.3 0.0 0.00026 20.7 0.0 2.2 2 0 0 2 2 2 2 Plant transposon protein Myb_DNA-bind_3 PF12776.7 OAJ24683.1 - 2.3e-14 54.2 0.6 3.5e-14 53.6 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ24683.1 - 0.0051 17.2 1.2 0.0082 16.5 0.4 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Zn_clus PF00172.18 OAJ24684.1 - 4.7e-06 26.6 9.9 9.8e-06 25.6 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ24684.1 - 7.4e-06 25.2 0.1 2.2e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugarporin_N PF11471.8 OAJ24684.1 - 0.13 12.2 3.3 0.72 9.8 3.3 2.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF1932 PF09130.11 OAJ24684.1 - 0.17 11.9 1.4 0.45 10.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) CDT1_C PF16679.5 OAJ24684.1 - 0.25 11.8 7.0 1.3 9.5 0.1 4.4 4 0 0 4 4 4 0 DNA replication factor Cdt1 C-terminal domain Proteasome PF00227.26 OAJ24685.1 - 6.3e-38 130.2 0.0 7.1e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit COX6A PF02046.15 OAJ24686.1 - 0.098 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Glyco_hydro_45 PF02015.16 OAJ24687.1 - 6.7e-50 169.9 3.1 8.4e-50 169.6 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Yae1_N PF09811.9 OAJ24688.1 - 0.00042 20.0 9.7 0.00074 19.2 9.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Lipase_3 PF01764.25 OAJ24689.1 - 1.5e-23 83.2 0.0 2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ24689.1 - 0.00034 21.3 0.3 0.00061 20.4 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ24689.1 - 0.0022 17.3 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAJ24689.1 - 0.02 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RHH_8 PF17723.1 OAJ24689.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family Aldo_ket_red PF00248.21 OAJ24692.1 - 4.8e-46 157.3 0.0 2.8e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Opi1 PF08618.10 OAJ24693.1 - 0.18 11.0 0.1 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DSBA PF01323.20 OAJ24694.1 - 3.5e-25 88.9 0.0 4.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RVT_1 PF00078.27 OAJ24695.1 - 3e-23 82.5 0.0 5.2e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ24695.1 - 1.7e-20 72.9 0.2 2.4e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ24695.1 - 5e-15 55.7 0.0 3.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ24695.1 - 1.9e-14 53.5 0.0 4.8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ24695.1 - 7.6e-10 39.0 0.0 2.6e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ24695.1 - 0.09 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger ArgoMid PF16487.5 OAJ24699.1 - 0.0042 17.3 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 OAJ24700.1 - 0.0025 17.6 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 PAZ domain DUF1797 PF08796.10 OAJ24700.1 - 0.041 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) API5 PF05918.11 OAJ24700.1 - 8.4 5.1 5.3 10 4.8 5.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_M13_N PF05649.13 OAJ24704.1 - 5.6e-06 26.3 0.0 6.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 eIF3m_C_helix PF18005.1 OAJ24708.1 - 8.8e-07 28.5 0.6 2.1e-06 27.3 0.6 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 OAJ24708.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 PCI domain Sec1 PF00995.23 OAJ24709.1 - 5.8e-34 118.3 0.0 6.6e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_63 PF03200.16 OAJ24711.1 - 6.4e-10 38.4 3.3 2.1e-07 30.1 0.3 4.2 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Methyltransf_16 PF10294.9 OAJ24711.1 - 6.1e-08 32.6 0.0 0.0043 16.8 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase ubiquitin PF00240.23 OAJ24713.1 - 1.1e-20 73.1 0.3 1.8e-20 72.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAJ24713.1 - 3e-14 52.6 4.3 2e-07 30.8 0.7 2.8 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 OAJ24713.1 - 2e-12 46.7 13.9 3.9e-12 45.7 13.9 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 OAJ24713.1 - 9.6e-06 25.3 0.5 1.5e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAJ24713.1 - 0.001 19.2 0.1 0.0021 18.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 OAJ24713.1 - 0.0076 16.0 0.0 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 UBA-like domain Ubiquitin_5 PF18037.1 OAJ24713.1 - 0.0088 16.4 0.2 0.019 15.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain MCM_N PF14551.6 OAJ24713.1 - 0.025 15.2 0.2 0.07 13.7 0.1 1.7 2 0 0 2 2 2 0 MCM N-terminal domain DUF2407 PF10302.9 OAJ24713.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CSTF2_hinge PF14327.6 OAJ24713.1 - 0.19 12.2 5.1 7.1 7.2 5.4 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Med13_C PF06333.12 OAJ24713.1 - 0.49 9.6 4.9 0.79 8.9 4.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Ndc1_Nup PF09531.10 OAJ24713.1 - 0.63 8.7 1.6 0.64 8.6 1.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.11 OAJ24713.1 - 1.8 6.8 5.2 2.3 6.4 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF483 PF04467.12 OAJ24714.1 - 0.0054 16.7 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF483) Ribosomal_L23 PF00276.20 OAJ24715.1 - 5.4e-07 29.9 0.0 3.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 MULE PF10551.9 OAJ24716.1 - 5.4e-08 33.2 0.2 1.7e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 OAJ24716.1 - 0.024 14.3 0.1 0.067 12.9 0.1 1.8 1 0 0 1 1 1 0 SWIM zinc finger DDE_Tnp_IS240 PF13610.6 OAJ24716.1 - 0.05 13.8 0.0 4.5 7.5 0.0 2.9 1 1 0 1 1 1 0 DDE domain Herpes_UL6 PF01763.16 OAJ24716.1 - 0.65 8.4 2.2 1.2 7.6 2.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like PNP_UDP_1 PF01048.20 OAJ24718.1 - 1.1e-35 123.0 0.6 1.3e-35 122.8 0.6 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily p450 PF00067.22 OAJ24719.1 - 1.4e-50 172.4 0.0 1.8e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4075 PF13294.6 OAJ24720.1 - 0.048 13.8 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) Pkinase PF00069.25 OAJ24721.1 - 4.4e-58 196.7 0.0 5.6e-34 117.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24721.1 - 1.9e-33 115.9 0.0 3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ24721.1 - 0.00011 22.3 0.1 0.00011 22.3 0.1 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ24721.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3584 PF12128.8 OAJ24721.1 - 0.068 10.7 11.9 0.11 9.9 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2203 PF09969.9 OAJ24721.1 - 0.69 10.6 7.1 0.24 12.1 3.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ubie_methyltran PF01209.18 OAJ24731.1 - 1e-70 237.7 0.0 1.6e-37 129.1 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAJ24731.1 - 1.2e-12 48.4 0.0 6.2e-11 42.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ24731.1 - 4.1e-12 46.6 0.0 7e-10 39.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ24731.1 - 2e-10 41.3 0.0 4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ24731.1 - 2.6e-07 30.5 0.0 2.6e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ24731.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAJ24731.1 - 0.0098 15.8 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase Glyco_transf_90 PF05686.12 OAJ24731.1 - 0.13 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Cullin PF00888.22 OAJ24732.1 - 1.2e-175 585.7 1.8 1.7e-175 585.2 1.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ24732.1 - 4.6e-27 93.8 1.6 1e-26 92.7 1.6 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 OAJ24732.1 - 0.015 15.6 2.9 15 6.0 0.1 4.0 4 0 0 4 4 4 0 Penicillinase repressor HTH_20 PF12840.7 OAJ24732.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4404 PF14357.6 OAJ24732.1 - 0.33 11.6 3.0 11 6.7 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) GPI-anchored PF10342.9 OAJ24733.1 - 1.4e-10 41.8 1.4 1.5e-10 41.7 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF11 PF01345.18 OAJ24733.1 - 0.38 11.1 6.2 3 8.2 4.9 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF11 DUF952 PF06108.12 OAJ24734.1 - 4.3e-14 52.3 0.0 5.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF1264 PF06884.11 OAJ24734.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) Glycos_transf_4 PF00953.21 OAJ24735.1 - 1e-32 113.3 6.7 2e-32 112.4 6.7 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 Mob1_phocein PF03637.17 OAJ24736.1 - 7e-59 198.6 0.8 9.2e-59 198.2 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family CAP59_mtransfer PF11735.8 OAJ24737.1 - 8.5e-70 235.2 0.0 1.4e-69 234.4 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Dicty_REP PF05086.12 OAJ24737.1 - 0.66 7.9 5.6 0.89 7.4 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.16 OAJ24739.1 - 5.4e-26 91.4 34.2 3.3e-17 62.4 11.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ24739.1 - 2.3e-14 53.1 4.4 2.3e-14 53.1 4.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Choline_transpo PF04515.12 OAJ24740.1 - 3.1e-78 263.3 25.9 3.1e-78 263.3 25.9 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter Pex14_N PF04695.13 OAJ24740.1 - 0.041 14.6 3.5 0.12 13.0 3.5 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fasciclin PF02469.22 OAJ24741.1 - 7e-28 97.4 8.1 8.1e-21 74.6 2.9 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF4993 PF16384.5 OAJ24741.1 - 0.012 14.6 0.7 0.077 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DIL PF01843.19 OAJ24741.1 - 0.16 12.2 0.6 0.44 10.8 0.6 1.7 1 0 0 1 1 1 0 DIL domain DnaJ PF00226.31 OAJ24742.1 - 1.3e-07 31.6 0.0 3.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_S9 PF00326.21 OAJ24743.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Bestrophin PF01062.21 OAJ24744.1 - 6.9e-15 55.2 0.1 4.3e-08 32.9 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF591 PF04569.14 OAJ24744.1 - 0.016 15.3 0.2 0.04 14.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function tRNA-synt_1c PF00749.21 OAJ24745.1 - 7.3e-107 356.9 0.0 1.3e-106 356.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAJ24745.1 - 4.8e-36 124.2 0.2 7.7e-36 123.6 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 OAJ24745.1 - 0.013 15.6 0.2 0.12 12.6 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ24745.1 - 0.026 14.7 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ24745.1 - 0.028 14.5 0.4 0.1 12.6 0.4 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DSS1_SEM1 PF05160.13 OAJ24745.1 - 0.032 14.3 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 DSS1/SEM1 family tRNA-synt_1e PF01406.19 OAJ24745.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CS PF04969.16 OAJ24746.1 - 7.8e-08 33.2 0.0 2.4e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 CS domain Isochorismatase PF00857.20 OAJ24747.1 - 1.2e-22 80.9 0.1 3e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family zf-ZPR1 PF03367.13 OAJ24748.1 - 1.1e-105 350.3 0.4 3.7e-52 176.4 0.0 2.7 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 OAJ24748.1 - 0.013 15.5 3.8 0.68 10.0 0.4 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 OAJ24748.1 - 0.024 14.7 8.4 6 7.0 0.4 3.3 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 OAJ24748.1 - 0.049 13.7 8.6 3.4 7.8 0.2 4.1 3 1 0 4 4 4 0 Double zinc ribbon DUF2688 PF10892.8 OAJ24748.1 - 0.11 11.9 0.1 0.41 10.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) zinc-ribbons_6 PF07191.12 OAJ24748.1 - 3.8 7.6 7.8 16 5.5 0.6 3.1 3 1 0 3 3 3 0 zinc-ribbons Fungal_trans PF04082.18 OAJ24749.1 - 2.1e-28 99.1 0.0 3.8e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAJ24749.1 - 1.5e-07 31.5 15.4 0.00026 21.2 0.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ24749.1 - 0.00042 20.9 10.7 0.0054 17.5 0.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ24749.1 - 0.02 15.5 3.3 3.3 8.4 0.1 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 OAJ24749.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 OAJ24749.1 - 0.67 10.1 4.8 0.3 11.2 1.6 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 OAJ24749.1 - 1 9.7 5.3 0.22 11.8 1.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon HSF_DNA-bind PF00447.17 OAJ24750.1 - 1.6e-19 70.3 0.0 1.7e-18 67.0 0.0 2.2 1 1 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.21 OAJ24751.1 - 9.2e-46 156.0 0.1 1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.7 OAJ24752.1 - 2e-05 24.4 0.2 4.3e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ24752.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain PI3K_1B_p101 PF10486.9 OAJ24752.1 - 0.12 10.2 1.9 0.19 9.4 1.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleo_P87 PF07267.11 OAJ24752.1 - 2.4 6.9 6.7 0.19 10.6 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PI-PLC-X PF00388.19 OAJ24753.1 - 2.5e-46 156.9 0.0 3.9e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAJ24753.1 - 1.5e-36 125.2 0.0 3e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAJ24753.1 - 0.029 14.7 0.0 0.098 13.0 0.0 1.9 1 1 0 1 1 1 0 C2 domain F-box-like PF12937.7 OAJ24757.1 - 0.019 14.8 0.3 0.05 13.5 0.1 1.8 2 0 0 2 2 2 0 F-box-like UPF0147 PF03685.13 OAJ24757.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Na_Ca_ex PF01699.24 OAJ24763.1 - 1.4e-24 86.7 24.3 3.9e-14 52.8 9.7 2.8 2 1 0 2 2 2 2 Sodium/calcium exchanger protein UBN_AB PF14075.6 OAJ24764.1 - 6.1e-29 101.3 0.0 6.1e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 OAJ24764.1 - 7.4e-11 41.9 0.1 7.4e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 HPC2 and ubinuclein domain DUF4207 PF13904.6 OAJ24764.1 - 0.0022 17.7 0.9 0.0022 17.7 0.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) FAM176 PF14851.6 OAJ24764.1 - 2.9 7.6 14.8 3.4 7.3 6.5 2.6 2 0 0 2 2 2 0 FAM176 family PPP4R2 PF09184.11 OAJ24764.1 - 9.6 5.7 14.8 4.2 6.9 8.2 2.5 2 0 0 2 2 2 0 PPP4R2 Aldo_ket_red PF00248.21 OAJ24766.1 - 7.5e-49 166.5 0.0 4.8e-48 163.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family ARGLU PF15346.6 OAJ24767.1 - 0.034 14.0 8.9 0.044 13.7 8.9 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Ribosomal_S17_N PF16205.5 OAJ24767.1 - 2.9 8.3 10.6 1.5 9.2 2.3 2.1 2 0 0 2 2 2 0 Ribosomal_S17 N-terminal B12D PF06522.11 OAJ24767.1 - 3.5 7.5 8.0 0.19 11.6 0.7 2.1 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RNase_PH_C PF03725.15 OAJ24769.1 - 0.095 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 H_lectin PF09458.10 OAJ24770.1 - 7e-08 32.5 0.0 0.0002 21.5 0.0 2.7 2 0 0 2 2 2 2 H-type lectin domain Endotoxin_N PF03945.14 OAJ24771.1 - 0.088 12.5 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain CCDC53 PF10152.9 OAJ24771.1 - 0.22 11.9 4.6 0.53 10.7 4.6 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Rnk_N PF14760.6 OAJ24773.1 - 0.054 14.0 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Rnk N-terminus T2SSK PF03934.13 OAJ24775.1 - 0.029 13.8 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Sigma54_CBD PF04963.13 OAJ24775.1 - 0.079 12.8 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain V-SNARE PF05008.15 OAJ24775.1 - 0.095 13.1 0.4 2 8.9 0.1 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus adh_short_C2 PF13561.6 OAJ24780.1 - 6.9e-54 182.9 1.9 1e-53 182.3 1.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ24780.1 - 1.7e-43 148.4 0.5 2.3e-43 147.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ24780.1 - 5.6e-10 39.4 3.8 1.2e-09 38.4 1.4 2.4 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAJ24780.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BLM10_mid PF16507.5 OAJ24781.1 - 2.7e-116 389.3 0.0 3.9e-116 388.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAJ24781.1 - 1e-17 63.8 0.0 8.9e-17 60.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 OAJ24781.1 - 0.00093 19.5 0.2 0.054 13.9 0.0 3.7 2 1 0 2 2 2 1 HEAT repeats TetR_C_30 PF17939.1 OAJ24781.1 - 0.098 12.9 2.3 2.1 8.6 0.0 3.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain HLH PF00010.26 OAJ24781.1 - 0.13 12.3 0.0 0.48 10.4 0.0 2.0 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain zf_C2H2_6 PF18450.1 OAJ24781.1 - 0.48 10.2 1.5 2.8 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc Finger domain NAPRTase PF04095.16 OAJ24782.1 - 2.7e-43 148.3 0.0 6.2e-33 114.4 0.0 3.3 2 1 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAJ24782.1 - 1.7e-30 106.0 0.1 2.5e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Exo_endo_phos PF03372.23 OAJ24783.1 - 1.5e-09 37.7 0.2 4.4e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family DUF2589 PF11655.8 OAJ24783.1 - 0.089 13.1 0.7 0.24 11.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) Robl_LC7 PF03259.17 OAJ24783.1 - 3.4 7.5 4.5 3.9 7.3 2.0 2.4 2 0 0 2 2 2 0 Roadblock/LC7 domain WD40 PF00400.32 OAJ24784.1 - 3.1e-07 31.0 5.0 0.033 15.1 0.1 3.4 3 1 0 3 3 3 3 WD domain, G-beta repeat COesterase PF00135.28 OAJ24785.1 - 1.7e-96 324.1 0.0 2.2e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ24785.1 - 2.3e-09 37.4 0.5 2.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF4131 PF13567.6 OAJ24787.1 - 0.12 12.1 1.2 0.25 11.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 OAJ24787.1 - 0.53 10.6 14.9 1.3 9.3 8.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2070 PF09843.9 OAJ24787.1 - 2.6 6.2 11.3 0.78 8.0 5.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Methyltransf_11 PF08241.12 OAJ24788.1 - 7.3e-07 29.7 0.0 4.2e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ24788.1 - 5e-06 27.1 0.3 0.00019 22.1 0.2 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ24788.1 - 0.00012 21.9 0.0 0.0006 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ24788.1 - 0.0071 17.1 0.0 0.02 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF3663 PF12404.8 OAJ24788.1 - 0.079 13.0 1.8 0.58 10.2 0.6 2.2 2 0 0 2 2 2 0 Peptidase Mt_ATP-synt_D PF05873.12 OAJ24790.1 - 1.2e-13 51.2 0.3 1.6e-13 50.8 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HsbA PF12296.8 OAJ24790.1 - 0.0028 18.0 0.9 0.035 14.5 0.2 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1366 PF07104.11 OAJ24790.1 - 0.012 15.3 1.5 0.02 14.6 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) MiaE_2 PF13794.6 OAJ24790.1 - 0.015 15.0 0.2 0.027 14.2 0.2 1.4 1 1 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like RPW8 PF05659.11 OAJ24790.1 - 0.016 14.9 1.4 0.21 11.3 0.5 2.6 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMPIT PF07851.13 OAJ24790.1 - 0.038 13.2 1.0 0.047 12.9 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Glyco_hydro_36N PF16875.5 OAJ24790.1 - 0.041 13.5 0.1 0.067 12.7 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain Phage_GP20 PF06810.11 OAJ24790.1 - 0.041 13.7 5.9 0.22 11.3 6.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 SUB1_ProdP9 PF18213.1 OAJ24790.1 - 0.06 13.2 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Cauli_AT PF03233.13 OAJ24790.1 - 0.11 12.4 1.3 0.19 11.6 1.3 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF2408 PF10303.9 OAJ24790.1 - 0.16 12.5 1.6 0.28 11.7 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Peptidase_M17_N PF02789.17 OAJ24790.1 - 0.18 11.7 0.2 0.18 11.7 0.2 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain MbeB_N PF04837.12 OAJ24790.1 - 0.31 11.4 3.3 0.2 12.0 0.9 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Pribosyltran PF00156.27 OAJ24791.1 - 0.00058 19.4 0.2 0.0042 16.6 0.2 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF3915 PF13054.6 OAJ24792.1 - 0.34 10.9 10.1 0.63 10.0 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3106 PF11304.8 OAJ24794.1 - 0.57 10.7 6.7 0.94 10.0 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Fe-ADH PF00465.19 OAJ24795.1 - 1.4e-66 224.8 0.0 1.8e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ24795.1 - 5.8e-16 59.0 0.6 1.2e-14 54.6 0.6 2.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OAJ24795.1 - 0.026 13.7 0.0 1 8.4 0.0 2.4 2 0 0 2 2 2 0 3-dehydroquinate synthase PFK PF00365.20 OAJ24795.1 - 0.057 12.7 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphofructokinase SPT16 PF08644.11 OAJ24796.1 - 2e-51 174.1 0.1 7.7e-51 172.2 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAJ24796.1 - 4.4e-44 150.1 1.1 1.2e-43 148.7 1.1 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAJ24796.1 - 1e-25 90.7 0.0 1.9e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAJ24796.1 - 2.1e-15 56.9 0.1 7.2e-15 55.2 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 OAJ24796.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Cys_Met_Meta_PP PF01053.20 OAJ24797.1 - 9.2e-120 399.7 0.0 4.1e-119 397.5 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 OAJ24797.1 - 6.7e-13 48.7 2.0 6.7e-13 48.7 2.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ24797.1 - 0.00012 22.4 0.4 0.0018 18.6 0.2 3.0 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAJ24797.1 - 0.00085 18.8 0.5 0.002 17.7 0.5 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.21 OAJ24797.1 - 0.081 12.1 0.5 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II HEAT PF02985.22 OAJ24798.1 - 3.2e-13 48.7 12.8 0.014 15.6 0.0 9.7 8 1 2 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 OAJ24798.1 - 6.9e-10 39.2 16.0 9.1e-06 26.0 0.1 5.8 5 2 0 5 5 5 3 HEAT repeats Cnd1 PF12717.7 OAJ24798.1 - 1.9e-05 24.7 3.2 0.036 14.1 0.0 4.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ24798.1 - 0.0031 16.2 3.6 0.089 11.3 0.0 2.8 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ24798.1 - 0.16 12.5 1.7 4.8 7.8 0.1 4.2 5 0 0 5 5 5 0 HEAT-like repeat Atg8 PF02991.16 OAJ24799.1 - 4.3e-52 174.7 0.2 5e-52 174.4 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAJ24799.1 - 6.3e-07 29.7 0.0 7.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Macro PF01661.21 OAJ24806.1 - 6.2e-42 142.4 0.1 9e-42 141.8 0.1 1.2 1 0 0 1 1 1 1 Macro domain Aminotran_3 PF00202.21 OAJ24807.1 - 7.7e-121 403.5 0.0 9.6e-121 403.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OAJ24807.1 - 0.04 13.2 0.0 0.24 10.6 0.0 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase Alpha_GJ PF03229.13 OAJ24807.1 - 4.7 7.8 8.6 1.3 9.6 5.4 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J ABC_membrane_2 PF06472.15 OAJ24808.1 - 4e-96 321.5 3.3 5.2e-96 321.2 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAJ24808.1 - 6.2e-20 72.1 0.0 2.1e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAJ24808.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ24808.1 - 0.013 16.0 4.1 0.11 13.0 4.1 2.3 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 OAJ24808.1 - 0.014 14.8 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 OAJ24808.1 - 0.048 13.6 0.3 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 OAJ24808.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 OAJ24808.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 OAJ24808.1 - 0.29 10.8 0.6 0.54 9.9 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain OMPdecase PF00215.24 OAJ24809.1 - 2.6e-74 249.6 0.0 3.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TauD PF02668.16 OAJ24809.1 - 0.073 12.9 0.2 10 5.8 0.0 2.1 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Elf1 PF05129.13 OAJ24810.1 - 2.3e-25 88.4 1.9 2.7e-25 88.2 1.9 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Acetyltransf_1 PF00583.25 OAJ24811.1 - 1.5e-09 38.1 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ24811.1 - 1.5e-06 28.2 0.1 2.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ24811.1 - 6.4e-06 26.5 0.2 1.2e-05 25.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ24811.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAJ24811.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain VPS9 PF02204.18 OAJ24813.1 - 3.7e-31 107.4 0.1 7e-31 106.5 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAJ24813.1 - 9.6e-12 45.0 0.0 2.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) SNARE PF05739.19 OAJ24813.1 - 0.01 15.8 1.7 0.023 14.7 0.0 2.3 3 0 0 3 3 3 0 SNARE domain Pre-PUA PF17832.1 OAJ24814.1 - 1.3e-24 86.7 0.0 1.9e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OAJ24814.1 - 3.7e-15 55.6 0.0 6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain MgtE PF01769.16 OAJ24815.1 - 4.6e-33 114.2 35.3 1.8e-20 73.6 4.0 4.6 4 1 0 4 4 4 2 Divalent cation transporter RbpA PF13397.6 OAJ24818.1 - 0.046 14.3 0.2 0.098 13.3 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase-binding protein NDC10_II PF16787.5 OAJ24819.1 - 2.4e-21 76.1 0.0 4.4e-21 75.3 0.0 1.4 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_28 PF13518.6 OAJ24819.1 - 0.00058 19.9 0.0 0.0037 17.4 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 OAJ24819.1 - 0.016 15.5 0.0 0.055 13.8 0.0 1.9 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 OAJ24819.1 - 0.041 13.9 0.0 0.66 10.0 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn helix MULE PF10551.9 OAJ24820.1 - 1.8e-22 79.5 0.1 4.6e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ24820.1 - 3.1e-08 32.9 0.0 4.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family zf-C2H2 PF00096.26 OAJ24822.1 - 4.7e-06 26.8 2.8 0.035 14.6 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ24822.1 - 0.0012 19.5 1.7 1.9 9.6 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Mpp10 PF04006.12 OAJ24822.1 - 6 5.2 15.0 0.84 8.0 9.1 2.0 2 0 0 2 2 2 0 Mpp10 protein SnoaL_2 PF12680.7 OAJ24823.1 - 0.00049 20.7 0.3 0.014 16.0 0.0 2.8 2 1 1 3 3 3 1 SnoaL-like domain BcrAD_BadFG PF01869.20 OAJ24824.1 - 1.2e-05 24.9 0.1 0.00017 21.2 0.1 2.1 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family CDC45 PF02724.14 OAJ24824.1 - 0.00082 17.8 0.6 0.00082 17.8 0.6 2.2 2 1 0 2 2 2 1 CDC45-like protein NOA36 PF06524.12 OAJ24824.1 - 2.2 7.5 10.4 5.6 6.2 10.4 1.6 1 0 0 1 1 1 0 NOA36 protein TFIIS_C PF01096.18 OAJ24825.1 - 1.5e-06 28.0 0.0 1.5e-06 28.0 0.0 3.3 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) C1_1 PF00130.22 OAJ24825.1 - 0.0077 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_POL_M_15KD PF02150.16 OAJ24825.1 - 0.0098 15.8 0.3 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zf-RING_12 PF17976.1 OAJ24825.1 - 0.17 12.2 2.7 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain HscB_4_cys PF18256.1 OAJ24825.1 - 1.8 8.5 6.1 2.9 7.8 0.6 2.7 2 1 1 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif ERG2_Sigma1R PF04622.12 OAJ24826.1 - 1.3e-88 295.8 0.0 1.6e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein RRM_1 PF00076.22 OAJ24827.1 - 2.5e-31 107.3 0.0 5.6e-12 45.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ24827.1 - 0.0011 18.5 0.0 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 OAJ24827.1 - 0.17 11.4 8.5 0.36 10.4 8.5 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ24827.1 - 4.2 7.2 10.1 0.25 11.3 4.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 OAJ24829.1 - 4.2e-10 39.5 10.3 4e-05 23.8 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ24829.1 - 6.5e-05 23.2 2.1 6.5e-05 23.2 2.1 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ24829.1 - 0.00024 21.7 9.0 0.16 12.9 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ24829.1 - 0.026 15.2 6.4 2.4 8.8 0.1 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain TPR_12 PF13424.6 OAJ24830.1 - 0.00034 20.8 13.5 0.028 14.7 0.7 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ24830.1 - 0.00075 19.3 1.7 7 6.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 OAJ24830.1 - 0.0091 16.0 0.3 0.4 10.8 0.2 2.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OAJ24830.1 - 0.067 13.3 14.8 1 9.7 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ24830.1 - 0.12 12.3 8.2 19 5.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ24830.1 - 0.32 11.3 3.8 13 6.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_C_6 PF17171.4 OAJ24831.1 - 3.9e-09 36.2 0.0 7.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAJ24831.1 - 0.00039 20.7 0.2 0.00069 19.9 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SUIM_assoc PF16619.5 OAJ24832.1 - 1.8e-06 27.9 6.3 0.15 12.1 0.0 2.9 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Oxysterol_BP PF01237.18 OAJ24833.1 - 1.2e-43 149.4 14.8 6.5e-27 94.3 2.4 4.1 2 1 1 3 3 3 2 Oxysterol-binding protein Pinin_SDK_memA PF04696.13 OAJ24833.1 - 0.68 10.0 8.3 0.11 12.5 1.7 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region zf-RVT PF13966.6 OAJ24834.1 - 0.00037 21.2 0.2 0.00061 20.5 0.2 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Arabinose_Iso_C PF11762.8 OAJ24834.1 - 0.029 14.2 0.6 0.048 13.5 0.0 1.7 2 0 0 2 2 2 0 L-arabinose isomerase C-terminal domain DUF3754 PF12576.8 OAJ24835.1 - 0.12 12.4 2.0 0.23 11.4 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) ADH_zinc_N PF00107.26 OAJ24836.1 - 1.2e-24 86.7 0.7 3.7e-24 85.2 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ24836.1 - 7.1e-16 59.5 0.0 2e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ24836.1 - 1.2e-07 31.6 0.0 1.8e-06 27.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ24836.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Trp_syntA PF00290.20 OAJ24837.1 - 1.5e-81 273.1 0.2 3.1e-81 272.0 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 OAJ24837.1 - 3.4e-49 167.8 0.8 6.8e-49 166.8 0.8 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 OAJ24837.1 - 1.3e-05 24.8 0.2 4.7e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein DFP PF04127.15 OAJ24837.1 - 0.04 13.7 0.1 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PA PF02225.22 OAJ24837.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.8 2 1 0 2 2 2 0 PA domain MULE PF10551.9 OAJ24838.1 - 0.0015 18.9 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ24838.1 - 0.14 12.8 1.7 0.63 10.8 1.7 2.1 1 0 0 1 1 1 0 FAR1 DNA-binding domain LTXXQ PF07813.12 OAJ24838.1 - 1 10.1 4.0 28 5.5 0.0 3.2 3 0 0 3 3 3 0 LTXXQ motif family protein Amidohydro_1 PF01979.20 OAJ24840.1 - 3.6e-59 200.8 0.0 2e-38 132.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAJ24840.1 - 2.3e-07 30.7 0.1 0.00065 19.3 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAJ24840.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 OAJ24841.1 - 1.6e-69 234.2 0.0 4.1e-69 232.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24841.1 - 2.9e-52 177.5 0.0 4.4e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ24841.1 - 1.7e-06 27.6 0.0 0.00019 20.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like CH PF00307.31 OAJ24841.1 - 2.3e-06 27.8 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Zn_ribbon_17 PF17120.5 OAJ24841.1 - 0.00033 20.2 3.7 0.0006 19.4 3.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 OAJ24841.1 - 0.00057 19.7 7.5 0.001 18.9 7.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CDC24 PF06395.11 OAJ24841.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin PHD PF00628.29 OAJ24841.1 - 0.41 10.6 7.1 0.76 9.7 7.1 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 OAJ24841.1 - 9 6.3 7.9 17 5.4 7.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NTP_transf_2 PF01909.23 OAJ24842.1 - 3.9e-05 23.9 0.0 7.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ24842.1 - 0.031 14.3 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3395 PF11875.8 OAJ24843.1 - 8e-41 139.5 0.0 1.7e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 OAJ24843.1 - 1e-20 73.6 0.7 1e-20 73.6 0.7 2.0 2 0 0 2 2 2 1 DnaJ domain Surp PF01805.20 OAJ24844.1 - 1.2e-11 44.4 0.3 2.4e-11 43.4 0.3 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 OAJ24844.1 - 6.2e-06 25.9 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.8 OAJ24844.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 OAJ24844.1 - 0.045 14.6 0.0 0.097 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Mito_carr PF00153.27 OAJ24845.1 - 8.8e-45 150.6 4.9 6.6e-16 58.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PMSR PF01625.21 OAJ24846.1 - 1.7e-56 190.6 0.3 2.1e-56 190.3 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GatB_N PF02934.15 OAJ24847.1 - 1.5e-85 286.9 0.0 1.6e-82 277.0 0.0 2.4 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAJ24847.1 - 1.6e-25 89.7 0.1 5.8e-14 52.2 0.0 2.5 3 0 0 3 3 3 2 GatB domain UvrD_C PF13361.6 OAJ24848.1 - 5.2e-15 55.7 0.1 9.1e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OAJ24848.1 - 4.7e-14 53.0 0.0 1.2e-13 51.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAJ24848.1 - 5.5e-11 42.1 0.1 2.2e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OAJ24848.1 - 9.2e-11 41.8 0.7 9.2e-11 41.8 0.7 3.2 4 1 0 4 4 4 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 OAJ24848.1 - 6e-09 35.9 0.0 0.00097 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAJ24848.1 - 2.2e-07 30.9 0.1 0.1 12.3 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase BORG_CEP PF14957.6 OAJ24848.1 - 0.088 14.0 3.2 1.1 10.5 0.2 2.7 2 0 0 2 2 2 0 Cdc42 effector Pkinase PF00069.25 OAJ24854.1 - 4.8e-50 170.4 0.0 7e-30 104.3 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24854.1 - 4.3e-22 78.7 0.0 8.5e-14 51.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ24854.1 - 0.00015 21.2 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OAJ24854.1 - 0.00067 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ24854.1 - 0.013 15.5 0.0 0.043 13.7 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ24854.1 - 0.083 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAJ24854.1 - 0.18 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIE-A_C PF11521.8 OAJ24854.1 - 2.5 8.5 8.0 0.59 10.5 3.7 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-C2H2_4 PF13894.6 OAJ24856.1 - 1.2e-05 25.8 6.7 0.056 14.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ24856.1 - 0.00013 22.2 12.3 0.0019 18.5 0.8 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAJ24856.1 - 0.053 13.5 0.9 0.12 12.4 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAJ24856.1 - 0.63 10.5 4.2 0.34 11.4 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.25 OAJ24857.1 - 1.1e-62 211.9 0.0 1.6e-61 208.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24857.1 - 3.5e-26 92.0 0.0 6.9e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ24857.1 - 2.1e-07 30.2 0.0 4.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ24857.1 - 0.0044 16.4 0.0 0.015 14.6 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ24857.1 - 0.066 12.0 0.0 0.066 12.0 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase Kinase-like PF14531.6 OAJ24857.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.5 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 OAJ24857.1 - 0.1 12.5 0.1 0.1 12.5 0.1 4.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAJ24857.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 OAJ24857.1 - 0.21 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3000 PF11452.8 OAJ24857.1 - 0.22 11.0 1.5 0.49 9.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Formyl_trans_N PF00551.19 OAJ24858.1 - 0.011 15.5 0.2 0.013 15.2 0.2 1.1 1 0 0 1 1 1 0 Formyl transferase Amidohydro_2 PF04909.14 OAJ24859.1 - 0.00054 19.8 0.0 0.23 11.2 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase DUF1754 PF08555.10 OAJ24859.1 - 0.25 12.2 2.4 0.6 10.9 2.4 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RIC1 PF07064.13 OAJ24861.1 - 1.2e-91 306.7 0.0 1.6e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 OAJ24861.1 - 0.0017 18.6 0.1 0.41 11.0 0.1 4.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribophorin_II PF05817.14 OAJ24862.1 - 6e-10 38.3 1.3 4.1e-07 28.9 1.0 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II HAT_KAT11 PF08214.11 OAJ24863.1 - 0.24 10.6 0.5 0.38 10.0 0.5 1.2 1 0 0 1 1 1 0 Histone acetylation protein Glyoxalase PF00903.25 OAJ24864.1 - 8.9e-05 22.7 0.0 0.0004 20.6 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAJ24864.1 - 0.12 12.4 0.0 5.8 6.9 0.0 2.5 3 0 0 3 3 3 0 Glyoxalase-like domain Pkinase_Tyr PF07714.17 OAJ24865.1 - 5.7e-07 29.1 0.0 0.0066 15.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ24865.1 - 1.8e-06 27.6 0.0 0.00057 19.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OAJ24865.1 - 0.00023 20.6 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ24865.1 - 0.0025 17.8 0.2 0.0059 16.6 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ24865.1 - 0.009 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OAJ24865.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GP67 PF17634.2 OAJ24865.1 - 0.31 11.5 6.2 0.68 10.4 6.2 1.5 1 0 0 1 1 1 0 Gene product 67 GalP_UDP_transf PF01087.22 OAJ24866.1 - 1.9e-60 204.5 0.1 2.8e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAJ24866.1 - 7.4e-42 142.9 0.0 2.4e-21 76.2 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 OAJ24866.1 - 0.075 11.8 0.0 6.7 5.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) GP57 PF17594.2 OAJ24866.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 WD40 PF00400.32 OAJ24867.1 - 0.00091 20.0 0.5 20 6.3 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat AT_hook PF02178.19 OAJ24867.1 - 0.00092 18.8 90.7 2.3 8.4 6.9 8.5 7 0 0 7 7 7 7 AT hook motif Rpn3_C PF08375.11 OAJ24869.1 - 1.3e-24 86.3 1.2 1.3e-24 86.3 1.2 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAJ24869.1 - 1.8e-17 63.8 0.1 4.8e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 OAJ24869.1 - 0.009 16.1 1.7 0.12 12.6 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ24869.1 - 1.2 9.9 9.7 1.6 9.5 1.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ24869.1 - 3.3 8.8 5.8 25 6.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN7a_helixI PF18392.1 OAJ24870.1 - 4.3e-05 23.3 0.2 7e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 OAJ24870.1 - 0.1 13.1 0.1 0.34 11.4 0.1 1.9 1 1 0 1 1 1 0 PCI domain DUF3767 PF12597.8 OAJ24871.1 - 1.3e-27 95.5 0.1 1.6e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) SSB PF00436.25 OAJ24872.1 - 3.1e-14 52.9 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family XRN_M PF17846.1 OAJ24874.1 - 3.1e-145 484.5 0.3 3.4e-108 362.4 0.0 2.5 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 OAJ24874.1 - 5.7e-100 333.7 0.0 1.1e-99 332.8 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 OAJ24874.1 - 0.00069 19.6 2.4 0.0016 18.4 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Antistasin PF02822.14 OAJ24874.1 - 0.22 12.2 1.1 2 9.1 0.7 2.4 2 0 0 2 2 2 0 Antistasin family ETC_C1_NDUFA5 PF04716.14 OAJ24876.1 - 2.3e-21 75.3 0.2 3.9e-21 74.6 0.2 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Prefoldin_2 PF01920.20 OAJ24876.1 - 0.00081 19.3 0.3 0.0013 18.7 0.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Abhydrolase_1 PF00561.20 OAJ24877.1 - 1.5e-18 67.4 0.3 6e-07 29.4 0.1 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ24877.1 - 9.4e-15 55.8 1.9 1.7e-14 55.0 1.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ24877.1 - 0.00026 20.3 0.1 0.0011 18.3 0.2 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 OAJ24877.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus TPP_enzyme_N PF02776.18 OAJ24878.1 - 3e-33 114.9 0.1 4.4e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAJ24878.1 - 4.7e-23 81.4 0.0 9.8e-22 77.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAJ24878.1 - 8.4e-16 58.1 0.2 1.5e-14 54.0 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cutinase PF01083.22 OAJ24879.1 - 8.4e-08 32.4 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF21 PF01595.20 OAJ24883.1 - 1e-36 126.3 0.4 2.3e-36 125.1 0.4 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAJ24883.1 - 3.1e-08 33.9 0.1 0.02 15.3 0.1 3.2 3 0 0 3 3 3 2 CBS domain PIN_4 PF13638.6 OAJ24884.1 - 9.9e-19 67.9 2.0 2.1e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 OAJ24884.1 - 2.4e-07 30.6 0.0 1.1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 OAJ24884.1 - 0.0066 16.7 0.2 0.49 10.7 0.0 2.8 2 1 0 2 2 2 1 PIN like domain YL1 PF05764.13 OAJ24884.1 - 0.011 15.9 1.1 0.011 15.9 1.1 2.1 2 0 0 2 2 2 0 YL1 nuclear protein eIF3_subunit PF08597.10 OAJ24884.1 - 0.11 12.4 10.4 0.28 11.1 10.4 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DNA_pol_phi PF04931.13 OAJ24884.1 - 1.3 7.0 7.7 2.2 6.3 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RT_RNaseH_2 PF17919.1 OAJ24885.1 - 1.1e-21 76.7 0.0 1.2e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ24885.1 - 6.3e-21 74.9 0.0 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ24885.1 - 1.4e-16 60.6 0.0 1.1e-10 41.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ24885.1 - 4.6e-12 46.2 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ24885.1 - 8e-07 29.1 1.6 2.6e-06 27.4 1.6 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain DPBB_1 PF03330.18 OAJ24887.1 - 0.00016 21.9 0.7 0.00063 20.0 0.7 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ24887.1 - 0.001 18.9 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Barwin family RVT_1 PF00078.27 OAJ24888.1 - 2.4e-24 86.1 0.0 4.1e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ24888.1 - 1.7e-14 53.6 0.0 3.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ24888.1 - 3.3e-13 49.5 0.1 5.7e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ24888.1 - 1.2e-12 48.0 0.0 3.9e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 OAJ24888.1 - 0.0006 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sigma70_ner PF04546.13 OAJ24889.1 - 1.5 8.7 3.9 6.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region BNIP2 PF12496.8 OAJ24889.1 - 1.8 9.0 7.0 0.45 11.0 1.0 2.3 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TFR_dimer PF04253.15 OAJ24891.1 - 1.8e-21 76.4 0.1 9.7e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAJ24891.1 - 4.8e-16 59.0 0.0 8.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ24891.1 - 4.1e-11 42.8 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 PA domain PPR_2 PF13041.6 OAJ24891.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family SOBP PF15279.6 OAJ24892.1 - 3.3 8.2 7.6 6.5 7.3 7.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein tRNA-synt_2 PF00152.20 OAJ24893.1 - 7.3e-74 248.7 0.0 9e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ24893.1 - 9.4e-11 41.6 0.0 2.8e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ24893.1 - 9.6e-08 31.8 0.0 0.00016 21.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DFRP_C PF16543.5 OAJ24894.1 - 6.3 7.4 10.0 0.47 11.0 0.2 3.4 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 Actin PF00022.19 OAJ24895.1 - 3.3e-48 164.3 0.0 4.8e-47 160.5 0.0 2.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAJ24895.1 - 0.008 15.0 0.0 0.02 13.7 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein CDC27 PF09507.10 OAJ24895.1 - 0.016 14.6 7.0 0.045 13.1 7.0 1.7 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2457 PF10446.9 OAJ24895.1 - 1.5 7.8 26.4 3.6 6.6 26.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 OAJ24895.1 - 7.6 5.8 20.3 11 5.4 16.5 2.2 2 0 0 2 2 2 0 SDA1 TFR_dimer PF04253.15 OAJ24896.1 - 2.2e-15 56.8 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAJ24896.1 - 4.3e-15 55.9 0.0 9.4e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ24896.1 - 4e-11 42.8 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1765 PF08578.10 OAJ24897.1 - 1.6e-26 93.2 1.5 2.6e-26 92.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) GATase_5 PF13507.6 OAJ24898.1 - 1.1e-93 313.0 0.0 1.7e-93 312.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAJ24898.1 - 1.4e-39 135.7 4.1 1.4e-25 90.2 0.1 2.6 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAJ24898.1 - 1.5e-30 105.5 0.0 3.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAJ24898.1 - 6e-21 74.7 0.0 1.4e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Tannase PF07519.11 OAJ24903.1 - 3.1e-38 131.9 0.2 4.9e-38 131.2 0.2 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.11 OAJ24904.1 - 5.4e-61 206.9 0.0 2.1e-60 205.0 0.0 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.11 OAJ24905.1 - 2.4e-38 132.3 0.0 1.2e-37 130.0 0.0 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase Mob1_phocein PF03637.17 OAJ24906.1 - 8.6e-77 256.9 0.1 1e-76 256.7 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Pyridoxal_deC PF00282.19 OAJ24907.1 - 8.1e-72 242.0 0.0 1e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAJ24907.1 - 6.1e-05 22.4 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAJ24907.1 - 6.4e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 OAJ24907.1 - 0.0045 15.8 0.0 0.0071 15.1 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain RRM_1 PF00076.22 OAJ24908.1 - 1.1e-26 92.4 0.9 7e-07 29.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OAJ24908.1 - 0.00043 20.1 0.0 2 8.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 OAJ24908.1 - 0.0012 18.6 0.0 11 5.9 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAJ24908.1 - 0.031 14.3 0.0 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 RNA binding motif DUF202 PF02656.15 OAJ24909.1 - 8.4e-19 67.8 1.4 1.5e-18 67.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Yae1_N PF09811.9 OAJ24910.1 - 1.9e-07 30.7 4.8 3.7e-07 29.7 4.8 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 OAJ24910.1 - 0.00022 21.0 0.1 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.22 OAJ24910.1 - 0.13 11.4 5.5 0.21 10.8 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EPL1 PF10513.9 OAJ24910.1 - 0.14 12.5 7.4 0.31 11.4 7.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like BORG_CEP PF14957.6 OAJ24910.1 - 0.78 10.9 7.9 0.37 11.9 4.3 2.2 2 0 0 2 2 2 0 Cdc42 effector PAT1 PF09770.9 OAJ24910.1 - 1.8 6.7 28.0 2.9 6.0 28.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.8 OAJ24910.1 - 3.1 6.5 8.7 5.4 5.7 8.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3292 PF11696.8 OAJ24910.1 - 5.8 5.2 12.3 8.6 4.6 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Endostatin PF06482.11 OAJ24910.1 - 7.8 5.9 15.7 14 5.0 15.7 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin AMP-binding PF00501.28 OAJ24911.1 - 2.8e-81 273.3 0.0 6.7e-58 196.3 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ24911.1 - 2.2e-11 44.5 0.0 5.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 OAJ24911.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DIL PF01843.19 OAJ24912.1 - 6.3e-27 93.9 1.0 1.3e-26 92.9 1.0 1.6 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 OAJ24912.1 - 7.4e-11 42.4 0.0 2.3e-09 37.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ24912.1 - 9.4e-11 42.2 0.0 6.2e-10 39.5 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ24912.1 - 8.1e-10 38.1 0.1 0.00074 19.8 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAJ24912.1 - 2.3e-07 30.9 0.0 2.3e-05 24.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ24912.1 - 5.2e-06 26.7 0.0 0.0033 17.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat UPF0061 PF02696.14 OAJ24914.1 - 6.4e-85 285.7 0.0 1.5e-84 284.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family adh_short PF00106.25 OAJ24915.1 - 3.3e-36 124.6 0.1 4.7e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24915.1 - 5.6e-29 101.4 0.3 9e-29 100.7 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ24915.1 - 7.7e-09 35.7 0.3 2.8e-08 33.9 0.3 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ24915.1 - 0.063 12.7 0.2 0.49 9.8 0.1 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family MmoB_DmpM PF02406.17 OAJ24915.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 MmoB/DmpM family Transket_pyr PF02779.24 OAJ24916.1 - 5.1e-47 159.8 0.0 9.4e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAJ24916.1 - 1.9e-39 134.3 0.1 9.3e-39 132.1 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain Hamartin PF04388.12 OAJ24916.1 - 1.8 7.1 3.3 2.3 6.8 3.3 1.1 1 0 0 1 1 1 0 Hamartin protein KTI12 PF08433.10 OAJ24917.1 - 2.4e-55 187.9 0.0 3.9e-55 187.2 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAJ24917.1 - 2.3e-08 34.3 0.5 7.5e-08 32.6 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ24917.1 - 0.0012 19.3 0.0 0.0034 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Aldedh PF00171.22 OAJ24918.1 - 1.5e-71 241.3 0.0 1.9e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family APG6_N PF17675.1 OAJ24919.1 - 0.016 15.7 23.6 0.016 15.7 23.6 5.8 3 2 3 6 6 6 0 Apg6 coiled-coil region Med9 PF07544.13 OAJ24919.1 - 0.04 14.0 0.5 0.04 14.0 0.5 5.5 5 2 1 7 7 7 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 OAJ24919.1 - 1 9.9 16.5 22 5.6 0.0 5.7 2 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 OAJ24919.1 - 2.7 6.8 73.1 0.12 11.2 31.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Sec34 PF04136.15 OAJ24919.1 - 4.1 7.3 19.9 8 6.3 2.2 4.5 2 2 3 5 5 5 0 Sec34-like family DFRP_C PF16543.5 OAJ24920.1 - 1.6e-28 99.0 3.1 1.6e-28 99.0 3.1 4.1 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_3 PF15663.5 OAJ24920.1 - 0.0045 17.2 4.6 0.039 14.2 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger containing family Torus PF16131.5 OAJ24920.1 - 0.31 11.7 11.6 17 6.2 0.0 4.2 3 1 0 3 3 3 0 Torus domain Cwf_Cwc_15 PF04889.12 OAJ24920.1 - 0.92 9.2 28.3 0.13 12.0 15.0 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-CCCH_2 PF14608.6 OAJ24920.1 - 2.2 8.9 9.7 8.5 7.0 1.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Lyase_1 PF00206.20 OAJ24921.1 - 1.1e-92 310.8 0.0 1.7e-92 310.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAJ24921.1 - 4e-25 88.4 0.1 1e-24 87.1 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal UAA PF08449.11 OAJ24922.1 - 2.2e-10 40.2 13.0 5.4e-06 25.8 0.9 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 OAJ24922.1 - 0.00046 20.4 4.2 0.00046 20.4 4.2 2.7 2 1 0 2 2 2 1 EamA-like transporter family PHO4 PF01384.20 OAJ24922.1 - 0.011 14.9 1.0 0.011 14.9 1.0 2.4 2 1 0 2 2 2 0 Phosphate transporter family Peptidase_M30 PF10460.9 OAJ24922.1 - 0.072 12.0 0.2 0.1 11.5 0.2 1.1 1 0 0 1 1 1 0 Peptidase M30 zf-RING_UBOX PF13445.6 OAJ24923.1 - 4.1e-07 29.9 6.6 4.1e-07 29.9 6.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ24923.1 - 1.3e-06 28.1 5.8 1.3e-06 28.1 5.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ24923.1 - 4.3e-06 26.5 7.2 2.4e-05 24.1 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ24923.1 - 6.4e-06 25.9 4.7 6.4e-06 25.9 4.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ24923.1 - 1.5e-05 25.2 4.0 1.5e-05 25.2 4.0 2.6 3 0 0 3 3 3 1 Ring finger domain DUF1644 PF07800.12 OAJ24923.1 - 0.00012 22.2 1.5 0.024 14.7 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 OAJ24923.1 - 0.00034 20.5 5.7 0.00034 20.5 5.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ24923.1 - 0.00043 20.1 6.9 0.0068 16.3 4.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ24923.1 - 0.0023 18.0 5.7 0.0023 18.0 5.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OAJ24923.1 - 2.6 7.9 6.3 5.8 6.8 6.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger HSP70 PF00012.20 OAJ24929.1 - 1.4e-39 135.8 10.6 3.5e-36 124.6 0.1 3.8 3 1 0 3 3 3 2 Hsp70 protein DUF4726 PF15855.5 OAJ24929.1 - 0.039 14.2 0.6 0.039 14.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) ATF7IP_BD PF16788.5 OAJ24929.1 - 0.2 11.7 4.5 0.52 10.4 4.5 1.6 1 0 0 1 1 1 0 ATF-interacting protein binding domain Myb_DNA-bind_3 PF12776.7 OAJ24930.1 - 3.8e-13 50.3 0.6 3.8e-13 50.3 0.6 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1752 PF08550.10 OAJ24930.1 - 6e-11 42.0 4.2 1.3e-10 40.9 4.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Myb_DNA-bind_4 PF13837.6 OAJ24930.1 - 0.045 14.1 0.9 0.11 12.9 0.9 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Mak16 PF04874.14 OAJ24930.1 - 3.5 8.3 8.6 0.2 12.3 2.3 2.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region DNA_pol_phi PF04931.13 OAJ24930.1 - 8.6 4.3 11.2 14 3.6 11.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi GMC_oxred_N PF00732.19 OAJ24931.1 - 5.5e-61 206.5 0.0 1.3e-60 205.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ24931.1 - 3.8e-28 98.8 0.1 7.8e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAJ24931.1 - 6e-05 22.8 0.3 0.0001 22.0 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ24931.1 - 7e-05 22.1 0.0 0.00057 19.1 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ24931.1 - 0.00011 22.4 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ24931.1 - 0.00035 19.9 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ24931.1 - 0.00038 19.6 0.2 0.00057 19.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAJ24931.1 - 0.0022 17.3 0.3 0.045 13.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ24931.1 - 0.022 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAJ24931.1 - 0.025 13.3 0.5 0.05 12.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 OAJ24931.1 - 0.15 11.3 0.0 5.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase RRM_1 PF00076.22 OAJ24932.1 - 1.5e-19 69.6 0.0 2e-11 43.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ24932.1 - 0.0055 16.8 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif SLX9 PF15341.6 OAJ24932.1 - 0.28 11.6 4.4 0.63 10.4 4.4 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PPR_2 PF13041.6 OAJ24933.1 - 0.061 13.5 0.0 1.5 9.1 0.0 3.1 4 0 0 4 4 4 0 PPR repeat family Pkinase PF00069.25 OAJ24934.1 - 1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24934.1 - 3e-31 108.6 0.0 4.6e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ24934.1 - 1e-06 28.3 0.4 0.0049 16.2 0.1 2.3 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 OAJ24934.1 - 0.0011 18.7 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OAJ24934.1 - 0.04 12.9 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAJ24934.1 - 0.062 13.2 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family SEEEED PF14797.6 OAJ24934.1 - 0.071 13.3 8.5 0.098 12.8 8.5 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Kdo PF06293.14 OAJ24934.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH_4 PF18044.1 OAJ24935.1 - 6.2e-07 29.1 14.1 0.0005 19.8 3.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAJ24935.1 - 3.5e-06 27.3 18.6 4.7e-06 26.9 6.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 OAJ24935.1 - 1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ24935.1 - 7.6e-05 22.9 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ24935.1 - 0.00011 22.3 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Torus PF16131.5 OAJ24935.1 - 0.00044 20.9 1.8 0.015 16.0 0.1 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 OAJ24935.1 - 0.001 18.9 12.7 0.033 14.1 2.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank PF00023.30 OAJ24935.1 - 0.0039 17.6 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat zf_CCCH_4 PF18345.1 OAJ24935.1 - 0.022 14.8 1.5 0.022 14.8 1.5 2.6 3 0 0 3 3 2 0 Zinc finger domain Ank_4 PF13637.6 OAJ24935.1 - 0.022 15.3 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) NST1 PF13945.6 OAJ24935.1 - 0.71 9.9 5.7 2.3 8.3 5.7 1.8 1 0 0 1 1 1 0 Salt tolerance down-regulator AMP-binding PF00501.28 OAJ24937.1 - 1.1e-68 231.8 0.0 1.6e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 OAJ24937.1 - 0.0018 17.9 9.7 2.2 8.1 0.7 6.1 7 1 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 OAJ24937.1 - 0.0035 17.7 0.0 0.0089 16.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site HLH PF00010.26 OAJ24939.1 - 0.053 13.5 0.8 0.1 12.6 0.8 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Dopey_N PF04118.14 OAJ24940.1 - 7.4e-105 350.4 0.0 2.8e-104 348.6 0.0 2.1 2 0 0 2 2 2 1 Dopey, N-terminal UCR_hinge PF02320.16 OAJ24941.1 - 4.2e-11 42.9 3.2 7.2e-11 42.1 3.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein ORC_WH_C PF18137.1 OAJ24941.1 - 0.017 15.2 2.0 0.023 14.7 2.0 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal CEND1 PF15677.5 OAJ24941.1 - 0.098 13.2 6.5 0.071 13.7 3.9 1.8 1 1 1 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 Merozoite_SPAM PF07133.11 OAJ24941.1 - 0.12 12.4 9.2 0.13 12.3 9.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3292 PF11696.8 OAJ24942.1 - 5.2e-202 672.7 0.0 4e-122 408.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Solute_trans_a PF03619.16 OAJ24943.1 - 1e-73 248.1 12.7 1.3e-73 247.8 12.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Nramp PF01566.18 OAJ24943.1 - 0.028 13.4 0.2 0.049 12.6 0.2 1.3 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein PepSY_TM PF03929.16 OAJ24943.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.4 2 1 0 2 2 2 0 PepSY-associated TM region Mon1 PF03164.14 OAJ24944.1 - 2e-79 267.6 0.0 1.3e-51 175.9 0.0 2.6 2 1 0 2 2 2 2 Trafficking protein Mon1 GST_N PF02798.20 OAJ24952.1 - 2.1e-12 47.2 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ24952.1 - 3.6e-12 46.5 0.0 6.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ24952.1 - 7e-10 39.0 0.1 1.2e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ24952.1 - 1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ24952.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ24952.1 - 4.3e-08 33.0 0.1 9.3e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEC-1_N PF04625.13 OAJ24953.1 - 0.37 9.8 11.7 0.53 9.2 11.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GST_N PF02798.20 OAJ24954.1 - 2.1e-12 47.2 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ24954.1 - 3.6e-12 46.5 0.0 6.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ24954.1 - 7e-10 39.0 0.1 1.2e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ24954.1 - 1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ24954.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ24954.1 - 4.3e-08 33.0 0.1 9.3e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ebp2 PF05890.12 OAJ24956.1 - 6.2e-76 255.5 3.3 6.2e-76 255.5 3.3 1.8 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF573 PF04504.14 OAJ24956.1 - 0.07 13.8 0.8 0.17 12.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Hamartin PF04388.12 OAJ24956.1 - 0.29 9.7 1.9 0.46 9.1 1.9 1.3 1 0 0 1 1 1 0 Hamartin protein Polysacc_deac_1 PF01522.21 OAJ24959.1 - 8.6e-23 80.6 0.0 1.6e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAJ24959.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) LRR_4 PF12799.7 OAJ24960.1 - 0.0003 21.1 1.3 9.3 6.8 0.0 5.2 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ24960.1 - 0.0087 16.0 6.0 2.1 8.6 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 OAJ24960.1 - 0.021 15.3 3.8 36 5.5 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.7 OAJ24960.1 - 0.029 14.3 0.4 0.094 12.6 0.4 1.9 1 1 0 1 1 1 0 F-box-like SDA1 PF05285.12 OAJ24960.1 - 0.031 13.7 0.2 0.031 13.7 0.2 2.2 2 0 0 2 2 2 0 SDA1 LRR_8 PF13855.6 OAJ24960.1 - 0.032 14.0 0.8 8.1 6.3 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat BUD22 PF09073.10 OAJ24960.1 - 1.3 8.3 22.2 1.7 7.9 6.1 2.2 2 0 0 2 2 2 0 BUD22 MFS_1 PF07690.16 OAJ24961.1 - 3.2e-17 62.5 31.1 3.2e-17 62.5 31.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAJ24961.1 - 1.5e-14 54.0 7.2 1.5e-14 54.0 7.2 2.8 4 1 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 OAJ24961.1 - 0.09 11.6 12.4 0.0085 15.0 6.2 2.3 1 1 2 3 3 3 0 MFS_1 like family MFS_1 PF07690.16 OAJ24962.1 - 6.2e-41 140.5 45.7 1.3e-40 139.4 43.1 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ24962.1 - 4.4e-17 61.7 10.6 4.4e-17 61.7 10.6 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ24962.1 - 1.5e-12 47.2 13.0 1.5e-12 47.2 13.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter bZIP_2 PF07716.15 OAJ24963.1 - 1.4e-08 34.7 12.4 1.4e-08 34.7 12.4 3.1 2 1 0 2 2 1 1 Basic region leucine zipper TFIIA PF03153.13 OAJ24963.1 - 2.6e-05 24.4 41.3 2.6e-05 24.4 41.3 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 OAJ24963.1 - 0.00081 19.6 7.4 0.00081 19.6 7.4 1.8 2 0 0 2 2 2 1 DDHD domain PAT1 PF09770.9 OAJ24963.1 - 0.011 14.0 33.1 0.017 13.5 33.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 OAJ24963.1 - 0.015 15.7 15.3 0.043 14.2 15.3 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like CLN3 PF02487.17 OAJ24963.1 - 0.019 14.0 9.4 0.031 13.3 9.4 1.2 1 0 0 1 1 1 0 CLN3 protein Velvet PF11754.8 OAJ24963.1 - 0.032 14.2 15.3 0.08 12.9 15.3 1.6 1 0 0 1 1 1 0 Velvet factor ABC2_membrane_2 PF12679.7 OAJ24963.1 - 0.046 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.22 OAJ24963.1 - 0.14 11.4 5.6 0.23 10.6 5.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 OAJ24963.1 - 0.87 6.6 20.9 1.2 6.2 20.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 OAJ24963.1 - 1.4 8.3 21.1 2.9 7.3 21.1 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin ALMT PF11744.8 OAJ24963.1 - 1.5 7.5 22.2 2.6 6.8 22.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 OAJ24963.1 - 1.6 7.7 21.4 3.1 6.7 21.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 YabA PF06156.13 OAJ24963.1 - 2 9.1 0.0 2 9.1 0.0 2.4 2 0 0 2 2 1 0 Initiation control protein YabA SpoIIP PF07454.11 OAJ24963.1 - 2.8 7.4 23.0 5.6 6.3 23.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DcuA_DcuB PF03605.14 OAJ24963.1 - 3 6.6 4.7 4.9 5.9 4.7 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF913 PF06025.12 OAJ24963.1 - 3.5 6.5 12.5 6.3 5.7 12.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 OAJ24963.1 - 4.7 5.5 10.0 6.6 5.0 10.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM222A PF15258.6 OAJ24963.1 - 5.4 6.0 42.5 11 5.0 42.5 1.5 1 0 0 1 1 1 0 Protein family of FAM222A Band_3_cyto PF07565.13 OAJ24963.1 - 5.9 6.6 20.8 11 5.7 20.8 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.11 OAJ24963.1 - 6.1 6.1 12.5 0.35 10.2 7.1 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein XPG_N PF00752.17 OAJ24964.1 - 9.9e-35 119.1 0.0 1.8e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ24964.1 - 2.5e-31 107.9 0.0 5.3e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OAJ24964.1 - 1.9e-07 31.6 0.0 5.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OAJ24964.1 - 0.0026 18.3 0.1 0.012 16.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 OAJ24964.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M20 PF01546.28 OAJ24965.1 - 1.2e-24 87.2 0.0 2.8e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAJ24965.1 - 3.5e-11 43.0 1.7 1.8e-10 40.7 1.7 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3152 PF11350.8 OAJ24965.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) BST2 PF16716.5 OAJ24965.1 - 0.14 12.8 1.1 0.29 11.7 1.1 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF3953 PF13129.6 OAJ24965.1 - 2.2 8.1 3.3 4.4 7.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) MFS_1 PF07690.16 OAJ24966.1 - 2.6e-32 112.2 29.7 8.2e-31 107.2 7.9 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ24966.1 - 7.9e-10 38.2 0.5 7.9e-10 38.2 0.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAJ24966.1 - 0.0057 16.0 5.4 0.0057 16.0 5.4 2.9 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PGA2 PF07543.12 OAJ24966.1 - 2.2 8.3 9.0 8.3 6.4 0.4 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Pro_CA PF00484.19 OAJ24968.1 - 4.4e-38 131.0 0.0 6.5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 OAJ24968.1 - 0.0065 16.1 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sda PF08970.10 OAJ24968.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Sporulation inhibitor A UreF PF01730.16 OAJ24969.1 - 5e-18 66.0 3.3 1e-17 65.0 3.3 1.5 1 0 0 1 1 1 1 UreF NUDE_C PF04880.13 OAJ24970.1 - 6.6e-14 52.8 10.7 6.6e-14 52.8 10.7 3.2 3 1 1 4 4 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.8 OAJ24970.1 - 7.8e-06 23.7 14.9 1.1e-05 23.3 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 OAJ24970.1 - 0.00021 21.4 23.4 0.0026 17.8 3.0 2.9 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DivIC PF04977.15 OAJ24970.1 - 0.0048 16.6 14.6 0.22 11.3 0.9 3.6 2 1 1 3 3 3 2 Septum formation initiator Filament PF00038.21 OAJ24970.1 - 0.008 15.8 7.4 0.008 15.8 7.4 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF2353 PF09789.9 OAJ24970.1 - 0.034 13.5 18.6 0.029 13.7 8.3 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Laminin_II PF06009.12 OAJ24970.1 - 0.041 13.9 17.6 0.034 14.1 5.3 3.6 2 1 2 4 4 3 0 Laminin Domain II Prefoldin_2 PF01920.20 OAJ24970.1 - 0.072 13.1 23.9 0.28 11.2 10.9 3.1 2 1 1 3 3 2 0 Prefoldin subunit Tektin PF03148.14 OAJ24970.1 - 0.072 11.8 20.9 1.5 7.5 15.8 2.4 1 1 1 2 2 2 0 Tektin family Phage_GP20 PF06810.11 OAJ24970.1 - 0.1 12.4 17.3 0.13 12.1 4.8 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 HALZ PF02183.18 OAJ24970.1 - 0.38 11.0 8.5 0.34 11.1 2.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 OAJ24970.1 - 0.44 11.0 25.5 0.17 12.4 5.9 3.8 2 1 3 5 5 4 0 Cell division protein ZapB DUF4407 PF14362.6 OAJ24970.1 - 0.49 9.7 9.9 0.17 11.2 4.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 OAJ24970.1 - 0.54 10.5 12.1 0.69 10.2 1.0 3.1 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.13 OAJ24970.1 - 0.58 10.3 9.8 0.45 10.6 2.8 3.4 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 OAJ24970.1 - 0.78 10.2 4.9 5.2 7.6 0.8 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 OAJ24970.1 - 0.79 7.8 25.6 3.1 5.9 4.6 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fmp27_WPPW PF10359.9 OAJ24970.1 - 0.97 8.2 15.5 1.4 7.7 0.5 2.3 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.12 OAJ24970.1 - 1 9.4 6.2 0.46 10.5 1.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 OAJ24970.1 - 1.1 9.0 20.5 0.78 9.5 17.2 2.3 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Bacillus_HBL PF05791.11 OAJ24970.1 - 1.3 8.8 7.4 0.23 11.3 3.5 1.7 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 OAJ24970.1 - 1.3 9.4 16.1 8.3 6.9 0.7 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 OAJ24970.1 - 1.5 8.3 22.4 3 7.2 12.5 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 ADIP PF11559.8 OAJ24970.1 - 1.5 8.9 19.7 0.32 11.1 10.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 OAJ24970.1 - 1.6 8.1 23.6 4.5 6.7 23.8 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PRKG1_interact PF15898.5 OAJ24970.1 - 1.9 9.5 27.6 0.049 14.5 12.5 2.8 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 OAJ24970.1 - 2 6.2 11.5 3.3 5.5 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 OAJ24970.1 - 2.4 6.9 23.2 0.36 9.6 13.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2115 PF09888.9 OAJ24970.1 - 2.4 8.6 5.3 3.2 8.3 4.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) RasGAP_C PF03836.15 OAJ24970.1 - 3.8 7.7 11.4 43 4.3 7.8 3.0 1 1 0 2 2 2 0 RasGAP C-terminus Syntaxin-6_N PF09177.11 OAJ24970.1 - 5 7.7 21.8 4.1 8.0 4.9 3.7 2 1 2 4 4 3 0 Syntaxin 6, N-terminal Prominin PF05478.11 OAJ24970.1 - 5.3 4.9 7.3 8.9 4.1 7.3 1.3 1 0 0 1 1 1 0 Prominin SKA1 PF07160.12 OAJ24970.1 - 5.6 6.7 13.6 1.5 8.6 8.0 2.2 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CENP-H PF05837.12 OAJ24970.1 - 6 7.3 21.8 2.8 8.4 4.0 3.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 OAJ24970.1 - 7 6.8 16.6 0.52 10.4 0.6 4.3 3 1 2 5 5 4 0 TolA binding protein trimerisation COG2 PF06148.11 OAJ24970.1 - 7.8 6.6 13.6 0.66 10.1 2.4 3.0 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 OAJ24970.1 - 7.9 5.5 14.5 11 5.0 8.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 OAJ24970.1 - 8 7.3 13.3 16 6.3 2.6 3.4 2 1 2 4 4 4 0 Occludin homology domain bZIP_1 PF00170.21 OAJ24970.1 - 8.3 6.6 19.0 1.5 9.0 1.5 4.0 3 1 1 4 4 4 0 bZIP transcription factor Cnn_1N PF07989.11 OAJ24970.1 - 9.1 6.5 15.8 22 5.3 0.9 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 ADH_N PF08240.12 OAJ24971.1 - 5.3e-25 87.4 3.6 5.3e-25 87.4 3.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ24971.1 - 1.1e-13 51.3 0.2 1.8e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ24971.1 - 0.00052 19.4 0.1 0.0013 18.2 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAJ24971.1 - 0.0057 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAJ24971.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 OAJ24971.1 - 0.019 13.7 0.1 0.045 12.5 0.0 1.6 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_2 PF03446.15 OAJ24971.1 - 0.029 14.6 0.2 0.067 13.4 0.2 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 OAJ24971.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF983 PF06170.12 OAJ24971.1 - 0.33 11.4 1.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) AMP-binding PF00501.28 OAJ24972.1 - 8.6e-13 47.7 0.1 6.4e-12 44.8 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme B12-binding PF02310.19 OAJ24972.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Med5 PF08689.10 OAJ24973.1 - 4e-23 81.3 0.0 5.6e-20 70.9 0.0 2.0 2 0 0 2 2 2 2 Mediator complex subunit Med5 COesterase PF00135.28 OAJ24974.1 - 1.1e-95 321.5 0.0 1.3e-95 321.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ24974.1 - 8e-10 38.9 1.0 5.6e-06 26.4 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ24974.1 - 0.011 15.2 0.2 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FMN_dh PF01070.18 OAJ24975.1 - 1.4e-101 340.0 0.2 4.3e-91 305.5 0.1 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAJ24975.1 - 4e-05 22.9 0.1 6.4e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAJ24975.1 - 0.00025 20.2 2.2 0.00046 19.3 2.0 1.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAJ24975.1 - 0.0089 15.4 0.7 1.9 7.7 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG TGT PF01702.18 OAJ24975.1 - 0.26 10.4 0.1 6.8 5.7 0.0 2.2 1 1 1 2 2 2 0 Queuine tRNA-ribosyltransferase COesterase PF00135.28 OAJ24977.1 - 3e-21 75.9 0.0 3.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Ribosomal_S26e PF01283.19 OAJ24983.1 - 1.9e-53 179.5 9.1 2.4e-53 179.1 9.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 OAJ24983.1 - 0.0057 17.2 1.6 0.016 15.8 1.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAJ24983.1 - 0.012 16.6 0.8 0.026 15.5 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OAJ24983.1 - 0.14 12.3 2.4 0.56 10.4 2.6 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 OAJ24983.1 - 0.17 11.8 0.8 0.17 11.8 0.8 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Pro_isomerase PF00160.21 OAJ24984.1 - 1.1e-46 159.0 0.0 1.5e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 OAJ24984.1 - 0.00034 20.5 5.6 0.28 11.4 0.7 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ24984.1 - 0.56 10.1 2.7 9.2 6.3 0.3 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Secretin_N PF03958.17 OAJ24985.1 - 0.24 11.8 2.0 0.77 10.2 0.3 2.8 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain HEAT PF02985.22 OAJ24986.1 - 9.2e-06 25.5 0.0 0.2 12.0 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 OAJ24986.1 - 2e-05 25.0 0.1 0.0019 18.7 0.0 3.0 2 1 1 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 OAJ24986.1 - 6.7e-05 23.2 0.0 0.29 11.5 0.0 2.4 2 1 0 2 2 2 2 HEAT repeats UME PF08064.13 OAJ24986.1 - 0.1 12.6 0.0 0.33 10.9 0.0 1.8 1 1 1 2 2 2 0 UME (NUC010) domain adh_short PF00106.25 OAJ24987.1 - 5.4e-23 81.5 0.0 1.4e-21 76.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24987.1 - 1.9e-18 66.9 0.0 3.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ24987.1 - 6.1e-07 29.5 0.0 9.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAJ24987.1 - 0.0093 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OAJ24987.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAJ24987.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAM165 PF14981.6 OAJ24987.1 - 0.023 14.5 0.9 0.04 13.7 0.9 1.3 1 0 0 1 1 1 0 FAM165 family TFIIB PF00382.19 OAJ24987.1 - 0.046 13.8 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 Transcription factor TFIIB repeat 2-Hacid_dh_C PF02826.19 OAJ24987.1 - 0.055 12.8 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HR1 PF02185.16 OAJ24987.1 - 0.084 13.0 1.2 0.15 12.2 1.2 1.4 1 0 0 1 1 1 0 Hr1 repeat NAD_binding_7 PF13241.6 OAJ24987.1 - 0.17 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.16 OAJ24988.1 - 8.9e-09 34.7 42.9 1.5e-07 30.7 35.3 3.2 1 1 1 2 2 2 1 Major Facilitator Superfamily PSRT PF07636.11 OAJ24988.1 - 0.13 11.9 5.1 0.37 10.5 5.1 1.7 1 0 0 1 1 1 0 PSRT PHD PF00628.29 OAJ24990.1 - 4e-07 29.8 8.4 4e-07 29.8 8.4 2.0 2 0 0 2 2 2 1 PHD-finger Retrotrans_gag PF03732.17 OAJ24992.1 - 0.12 12.7 0.4 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Glyco_hydro_130 PF04041.13 OAJ24994.1 - 0.027 13.4 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase DUF4449 PF14613.6 OAJ24994.1 - 0.036 14.2 0.5 0.036 14.2 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4449) Cofilin_ADF PF00241.20 OAJ24995.1 - 1.3e-19 70.2 0.0 1.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TraX PF05857.11 OAJ24995.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 TraX protein IBR PF01485.21 OAJ24996.1 - 1.2e-20 73.4 46.8 5.1e-12 45.8 6.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAJ24996.1 - 0.00044 20.1 5.8 0.00044 20.1 5.8 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ24996.1 - 0.0067 16.7 5.3 0.0067 16.7 5.3 4.0 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ24996.1 - 0.008 16.2 2.1 0.008 16.2 2.1 4.0 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ24996.1 - 0.019 14.8 4.0 0.019 14.8 4.0 4.6 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 OAJ24997.1 - 2.6e-15 56.0 0.0 9.1e-07 28.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ24997.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif TAF PF02969.17 OAJ24998.1 - 1.5e-21 76.3 0.0 3.8e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 OAJ24998.1 - 2.8e-14 53.2 0.0 8e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 OAJ24998.1 - 5.2e-05 23.6 0.8 0.00011 22.5 0.5 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OAJ24998.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Spt5_N PF11942.8 OAJ24998.1 - 0.046 14.7 5.2 0.37 11.8 1.6 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 OAJ24998.1 - 0.1 12.9 1.1 3.2 8.0 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) WD40 PF00400.32 OAJ24999.1 - 1.5e-11 44.6 5.3 0.041 14.8 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 OAJ24999.1 - 0.073 11.7 0.6 0.41 9.2 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF1241 PF06840.11 OAJ24999.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) zf-C3HC4_2 PF13923.6 OAJ25000.1 - 4.7e-08 32.7 13.6 7.5e-08 32.1 13.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ25000.1 - 3.8e-07 30.3 13.3 6e-07 29.7 13.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ25000.1 - 2.5e-06 27.2 13.0 4.2e-06 26.5 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ25000.1 - 6.3e-06 26.0 14.4 9.3e-06 25.4 14.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ25000.1 - 0.00017 21.5 13.5 0.00029 20.7 13.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAJ25000.1 - 0.0052 17.1 11.2 0.012 15.9 11.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3450 PF11932.8 OAJ25000.1 - 0.0055 16.0 0.1 0.0087 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Taxilin PF09728.9 OAJ25000.1 - 0.0057 15.9 0.7 0.0092 15.2 0.7 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Prok-RING_4 PF14447.6 OAJ25000.1 - 0.0068 16.2 10.7 0.015 15.2 10.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAJ25000.1 - 0.0069 16.4 10.9 0.013 15.5 10.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAJ25000.1 - 0.012 15.7 12.4 0.023 14.8 12.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OAJ25000.1 - 0.024 14.8 5.4 0.042 14.0 5.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 TolA_bind_tri PF16331.5 OAJ25000.1 - 0.031 14.3 0.2 0.061 13.4 0.2 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation YlqD PF11068.8 OAJ25000.1 - 0.061 13.7 1.8 0.12 12.7 1.8 1.4 1 0 0 1 1 1 0 YlqD protein TMF_DNA_bd PF12329.8 OAJ25000.1 - 0.07 13.1 2.1 0.13 12.2 2.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 OAJ25000.1 - 0.13 11.1 1.4 0.2 10.5 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 OAJ25000.1 - 0.25 11.6 0.4 0.47 10.7 0.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA zf-RING_6 PF14835.6 OAJ25000.1 - 1.6 8.6 9.0 2.8 7.9 9.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OAJ25000.1 - 4.3 7.2 12.7 7.4 6.5 12.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pellino PF04710.14 OAJ25000.1 - 5.8 5.5 6.7 0.3 9.7 0.8 1.7 2 0 0 2 2 2 0 Pellino Uds1 PF15456.6 OAJ25000.1 - 9.3 6.4 10.3 32 4.7 10.3 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Ras PF00071.22 OAJ25001.1 - 1.3e-64 216.7 0.8 1.5e-64 216.5 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ25001.1 - 5e-36 123.5 0.1 7.9e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ25001.1 - 2.3e-17 63.0 0.1 2.9e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ25001.1 - 4e-06 26.8 1.0 0.042 13.7 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 OAJ25001.1 - 6.4e-06 25.7 0.1 7.6e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ25001.1 - 1.1e-05 25.1 0.3 2.8e-05 23.7 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ25001.1 - 5e-05 23.3 0.0 7.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ25001.1 - 9.2e-05 21.9 0.1 0.00012 21.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAJ25001.1 - 0.0027 17.2 0.1 0.021 14.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OAJ25001.1 - 0.0087 16.5 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAJ25001.1 - 0.0093 16.4 0.1 0.53 10.7 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAJ25001.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OAJ25001.1 - 0.05 13.6 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ25001.1 - 0.058 13.7 0.0 0.086 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAJ25001.1 - 0.078 12.4 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OAJ25001.1 - 0.08 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AIRC PF00731.20 OAJ25001.1 - 0.091 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 AIR carboxylase PduV-EutP PF10662.9 OAJ25001.1 - 0.093 12.5 0.0 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OAJ25001.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 OAJ25001.1 - 0.17 11.5 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain COG4 PF08318.12 OAJ25002.1 - 9.9e-73 245.1 0.0 3.5e-72 243.3 0.0 1.8 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 OAJ25002.1 - 0.17 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family PIRT PF15099.6 OAJ25004.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.3 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family TMEM154 PF15102.6 OAJ25004.1 - 0.61 10.0 2.2 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Ribosomal_60s PF00428.19 OAJ25005.1 - 0.023 15.2 3.2 0.051 14.2 3.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SWIRM-assoc_2 PF16496.5 OAJ25005.1 - 2.7 6.8 9.2 3.5 6.4 9.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pro_isomerase PF00160.21 OAJ25007.1 - 6.1e-48 163.1 0.1 1.8e-47 161.6 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAJ25007.1 - 8.5e-11 42.2 1.3 0.00097 19.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ25007.1 - 0.00084 19.6 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ25007.1 - 0.033 13.1 0.8 0.86 8.5 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Prefoldin_2 PF01920.20 OAJ25008.1 - 4.3e-17 62.0 7.9 5.5e-17 61.7 7.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 OAJ25008.1 - 0.014 15.6 1.4 0.014 15.6 1.4 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF2408 PF10303.9 OAJ25008.1 - 0.03 14.9 2.7 0.04 14.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Cortex-I_coil PF09304.10 OAJ25008.1 - 0.69 10.2 7.3 0.22 11.8 1.1 2.2 1 1 0 2 2 2 0 Cortexillin I, coiled coil Coat_F PF07875.12 OAJ25008.1 - 1 9.7 4.2 8.1 6.8 0.3 2.7 2 1 1 3 3 3 0 Coat F domain Cep57_MT_bd PF06657.13 OAJ25008.1 - 1.7 9.2 8.6 11 6.6 0.4 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FlxA PF14282.6 OAJ25008.1 - 3.1 7.8 11.9 1.7 8.7 0.3 2.3 2 0 0 2 2 2 0 FlxA-like protein Cyt-b5 PF00173.28 OAJ25012.1 - 9.3e-09 35.3 0.1 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.18 OAJ25013.1 - 1.5e-19 70.1 0.0 4e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2722 PF10846.8 OAJ25013.1 - 0.0012 17.9 2.7 0.0012 17.9 2.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 OAJ25013.1 - 0.0019 18.3 15.0 0.0021 18.1 3.5 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 OAJ25013.1 - 0.87 8.5 30.6 0.17 10.8 19.5 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SR-25 PF10500.9 OAJ25013.1 - 2.9 7.4 8.2 15 5.1 4.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 OAJ25013.1 - 4.2 8.0 17.3 1.3 9.7 3.4 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 OAJ25013.1 - 8.2 6.7 8.8 1.7 8.9 0.4 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF5020 PF16412.5 OAJ25014.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) DUF3712 PF12505.8 OAJ25016.1 - 1.4e-109 361.3 42.8 9.6e-24 84.0 0.0 10.3 10 0 0 10 10 10 8 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAJ25016.1 - 0.00025 21.5 19.5 0.17 12.4 0.1 7.6 8 0 0 8 8 8 3 Late embryogenesis abundant protein LON_substr_bdg PF02190.16 OAJ25017.1 - 6e-25 88.4 0.0 2.8e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAJ25017.1 - 5.2e-15 55.0 21.2 6.4e-11 41.9 9.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ25017.1 - 1e-11 44.7 19.7 2.1e-06 27.7 3.6 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ25017.1 - 2.3e-10 40.2 17.3 5.7e-07 29.3 5.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ25017.1 - 6.8e-10 38.9 20.8 7.9e-06 25.9 3.7 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ25017.1 - 1.6e-09 37.9 20.4 6.6e-07 29.6 9.2 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 OAJ25017.1 - 4.6e-09 36.0 21.1 5.9e-05 22.9 8.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ25017.1 - 1.1e-08 34.9 19.0 3.3e-05 23.8 8.0 2.4 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ25017.1 - 2.4e-08 33.7 19.6 2.1e-06 27.5 7.0 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAJ25017.1 - 0.0015 18.6 14.1 0.003 17.6 3.4 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OAJ25017.1 - 0.0045 16.8 3.5 0.0045 16.8 3.5 3.1 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 OAJ25017.1 - 0.021 14.7 17.1 0.045 13.6 1.4 3.0 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OAJ25017.1 - 0.21 11.9 13.3 0.047 14.0 6.3 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 OAJ25017.1 - 5.6 6.7 14.6 0.17 11.6 6.9 2.2 2 0 0 2 2 2 0 P-11 zinc finger CLTH PF10607.9 OAJ25018.1 - 1.4e-18 67.2 0.0 6e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF4248 PF14053.6 OAJ25018.1 - 0.096 12.7 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) EF1_GNE PF00736.19 OAJ25019.1 - 2.1e-32 111.2 1.4 3.4e-32 110.5 1.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAJ25019.1 - 1.5e-11 44.5 6.2 1.5e-11 44.5 6.2 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 OAJ25019.1 - 0.00036 20.5 0.3 0.0026 17.7 0.3 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ25019.1 - 0.00083 19.5 0.3 0.0038 17.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ25019.1 - 0.001 19.2 0.1 0.003 17.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 OAJ25019.1 - 0.011 15.5 4.3 0.015 15.1 4.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_6 PF17171.4 OAJ25019.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 OAJ25019.1 - 0.23 11.1 3.9 0.29 10.7 3.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3246 PF11596.8 OAJ25019.1 - 5.3 6.4 6.5 6.3 6.2 5.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) MAJIN PF15077.6 OAJ25020.1 - 1.7 8.4 21.4 0.093 12.5 14.9 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein SOBP PF15279.6 OAJ25020.1 - 7.8 7.0 34.4 5.3 7.6 29.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein DS PF01916.17 OAJ25022.1 - 2.3e-130 434.0 0.0 3.3e-130 433.5 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA PF00004.29 OAJ25022.1 - 1.4e-57 193.8 0.0 7.2e-45 152.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ25022.1 - 4.2e-08 33.7 0.6 0.011 16.2 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 OAJ25022.1 - 1.6e-07 31.0 5.9 0.00054 19.7 1.6 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_18 PF13238.6 OAJ25022.1 - 3.5e-05 24.4 0.0 0.048 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ25022.1 - 6e-05 23.1 0.1 0.045 13.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ25022.1 - 0.00054 19.7 0.0 0.007 16.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAJ25022.1 - 0.0011 19.1 0.0 0.59 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAJ25022.1 - 0.0012 18.8 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OAJ25022.1 - 0.0014 18.9 0.2 0.04 14.2 0.1 2.8 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.6 OAJ25022.1 - 0.0019 18.2 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAJ25022.1 - 0.0025 17.5 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 OAJ25022.1 - 0.003 17.8 0.0 0.77 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAJ25022.1 - 0.0043 16.4 0.2 0.0087 15.4 0.0 1.5 2 0 0 2 2 1 1 KaiC AAA_25 PF13481.6 OAJ25022.1 - 0.0048 16.5 0.1 0.032 13.8 0.1 2.0 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ25022.1 - 0.0049 16.1 0.0 0.052 12.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 OAJ25022.1 - 0.0054 15.9 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OAJ25022.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAJ25022.1 - 0.01 16.0 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.14 OAJ25022.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 OAJ25022.1 - 0.014 14.6 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 OAJ25022.1 - 0.016 14.6 0.3 0.073 12.4 0.1 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAJ25022.1 - 0.033 13.7 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ25022.1 - 0.038 14.4 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAJ25022.1 - 0.058 13.3 1.7 5.4 6.9 0.1 2.9 3 0 0 3 3 2 0 NACHT domain Vps4_C PF09336.10 OAJ25022.1 - 0.087 12.8 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 OAJ25022.1 - 0.1 12.5 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OAJ25022.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 OAJ25022.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OAJ25022.1 - 0.14 11.9 0.4 15 5.2 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase Cupin_8 PF13621.6 OAJ25024.1 - 9.4e-54 182.8 0.0 1.2e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 OAJ25024.1 - 0.016 14.9 0.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.22 OAJ25024.1 - 0.049 14.1 0.1 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase PI3_PI4_kinase PF00454.27 OAJ25025.1 - 6.6e-33 114.6 0.0 1.2e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OAJ25025.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) adh_short PF00106.25 OAJ25026.1 - 2.2e-21 76.2 0.0 3.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ25026.1 - 1e-17 64.5 0.2 1.3e-17 64.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ25026.1 - 8.5e-11 42.1 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ25026.1 - 2.8e-07 30.2 0.5 4.3e-06 26.4 0.5 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ25026.1 - 0.00014 21.4 0.1 0.049 13.0 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 OAJ25026.1 - 0.00015 21.8 0.1 0.00084 19.5 0.2 2.0 1 1 1 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAJ25026.1 - 0.001 18.3 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 OAJ25026.1 - 0.011 15.6 1.5 0.076 12.9 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ25026.1 - 0.085 13.4 1.1 0.37 11.4 0.7 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAJ25026.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3712 PF12505.8 OAJ25027.1 - 2.5e-107 354.1 43.9 5.9e-24 84.7 0.1 8.2 8 0 0 8 8 8 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAJ25027.1 - 8.3e-08 32.7 15.0 0.051 14.1 0.1 7.6 8 0 0 8 8 8 3 Late embryogenesis abundant protein Kelch_4 PF13418.6 OAJ25028.1 - 5.1e-11 42.4 1.8 0.02 14.9 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ25028.1 - 1.2e-10 41.3 2.1 0.051 13.9 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OAJ25028.1 - 8.7e-08 32.0 0.1 0.00012 21.9 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 OAJ25028.1 - 2.4e-06 27.0 0.3 0.77 9.4 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OAJ25028.1 - 4.6e-05 23.6 11.6 5.9e-05 23.3 0.1 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ25028.1 - 0.00013 21.7 0.3 0.012 15.6 0.1 3.6 2 0 0 2 2 2 1 Kelch motif LrgB PF04172.16 OAJ25033.1 - 4.9e-24 85.1 0.9 1.4e-23 83.6 0.9 1.8 1 0 0 1 1 1 1 LrgB-like family LrgA PF03788.14 OAJ25033.1 - 0.0041 17.0 6.9 0.0042 17.0 0.4 3.7 2 2 1 3 3 3 1 LrgA family DsbG_N PF18257.1 OAJ25034.1 - 0.085 13.0 0.0 4.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Palm_thioest PF02089.15 OAJ25034.1 - 0.16 11.7 0.1 0.45 10.3 0.0 1.6 1 1 1 2 2 2 0 Palmitoyl protein thioesterase Gp_dh_C PF02800.20 OAJ25035.1 - 4.4e-69 231.1 0.0 5.9e-69 230.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAJ25035.1 - 2e-38 130.8 0.1 4.1e-38 129.8 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain G_glu_transpept PF01019.21 OAJ25036.1 - 3.4e-142 474.8 0.0 2.6e-122 409.2 0.0 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Peroxidase_2 PF01328.17 OAJ25039.1 - 3.3e-53 181.0 0.0 4.6e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 SNF5 PF04855.12 OAJ25040.1 - 3.6e-59 200.4 2.0 3.6e-59 200.4 2.0 4.1 3 1 1 4 4 4 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 OAJ25040.1 - 0.0097 15.5 1.3 0.026 14.1 1.3 1.8 1 0 0 1 1 1 1 GATA zinc finger FYDLN_acid PF09538.10 OAJ25040.1 - 0.18 12.5 0.1 0.18 12.5 0.1 6.0 6 0 0 6 6 6 0 Protein of unknown function (FYDLN_acid) cwf18 PF08315.12 OAJ25042.1 - 1.8e-29 103.1 8.6 2.5e-29 102.7 8.6 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor RRM_1 PF00076.22 OAJ25043.1 - 5.9e-33 112.5 0.0 4.1e-17 61.8 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ25043.1 - 0.00038 20.5 0.0 0.0022 18.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 OAJ25043.1 - 0.0008 19.0 0.0 0.37 10.4 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAJ25043.1 - 0.083 13.1 0.0 5.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 OAJ25043.1 - 0.086 12.5 0.2 0.27 10.9 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain EF1G PF00647.19 OAJ25044.1 - 4.7e-47 158.5 0.3 9e-47 157.6 0.3 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 OAJ25044.1 - 2.4e-16 59.8 0.2 1.1e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ25044.1 - 1.7e-12 47.3 0.0 4.3e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ25044.1 - 1.5e-08 34.5 0.0 3.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ25044.1 - 8.1e-07 29.2 0.2 3.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ25044.1 - 3.5e-06 27.3 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ25044.1 - 1.8e-05 24.9 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SRP-alpha_N PF04086.13 OAJ25044.1 - 0.014 15.3 0.5 0.021 14.7 0.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_60s PF00428.19 OAJ25044.1 - 2 9.1 13.1 5.3 7.7 13.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein OAD_gamma PF04277.13 OAJ25044.1 - 8.4 7.1 8.6 17 6.1 8.6 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CPDase PF07823.11 OAJ25045.1 - 1.2e-17 64.2 0.0 2.6e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OAJ25045.1 - 1.5e-05 24.9 0.1 6.6e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3349 PF11829.8 OAJ25045.1 - 0.086 13.6 0.0 0.22 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HemN_C PF06969.16 OAJ25045.1 - 0.12 12.4 0.1 0.79 9.8 0.1 2.1 1 1 0 1 1 1 0 HemN C-terminal domain RhoGEF PF00621.20 OAJ25046.1 - 2.1e-35 122.6 0.2 3.2e-35 122.0 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 OAJ25046.1 - 1.7e-31 109.1 0.0 3.4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 OAJ25046.1 - 6.9e-21 74.3 0.2 2e-12 47.2 0.1 2.5 2 0 0 2 2 2 2 CDC24 Calponin PB1 PF00564.24 OAJ25046.1 - 4.8e-10 39.2 0.2 8.7e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 OAJ25046.1 - 0.0034 17.9 0.1 0.016 15.7 0.1 2.1 1 1 0 1 1 1 1 PH domain Glyco_hydro_25 PF01183.20 OAJ25047.1 - 2.4e-48 164.7 2.5 3e-48 164.4 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RNA_pol PF00940.19 OAJ25049.1 - 2.6e-171 570.0 0.0 3.6e-171 569.6 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAJ25049.1 - 9.4e-84 281.7 1.3 9.4e-84 281.7 1.3 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal AP3D1 PF06375.11 OAJ25049.1 - 0.0054 17.0 1.4 0.012 15.8 1.4 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 HEAT PF02985.22 OAJ25050.1 - 6.3e-25 85.1 10.9 0.00031 20.8 0.0 11.3 12 0 0 12 12 10 4 HEAT repeat HEAT_EZ PF13513.6 OAJ25050.1 - 7.6e-16 58.2 15.2 8.7e-10 38.9 0.1 8.3 9 0 0 9 9 8 2 HEAT-like repeat HEAT_2 PF13646.6 OAJ25050.1 - 9.6e-13 48.3 9.3 0.036 14.4 0.0 6.5 2 2 4 6 6 6 5 HEAT repeats IBN_N PF03810.19 OAJ25050.1 - 4.3e-10 39.4 1.8 8.7e-07 28.8 0.2 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 OAJ25050.1 - 0.00022 21.1 11.1 0.0089 16.0 0.1 5.4 6 1 0 6 6 6 2 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 OAJ25050.1 - 0.00066 19.5 0.7 3.4 7.4 0.0 3.8 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.7 OAJ25050.1 - 0.00079 20.0 0.1 0.58 10.8 0.1 4.7 5 1 2 7 7 6 2 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 OAJ25050.1 - 0.0017 18.0 0.2 0.057 13.0 0.5 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF3385 PF11865.8 OAJ25050.1 - 0.005 16.8 0.4 6 6.8 0.0 4.3 2 1 2 5 5 5 1 Domain of unknown function (DUF3385) Xpo1 PF08389.12 OAJ25050.1 - 0.0068 16.5 0.5 0.21 11.6 0.1 3.2 2 1 1 3 3 3 1 Exportin 1-like protein CLASP_N PF12348.8 OAJ25050.1 - 0.1 12.2 0.3 3.7 7.0 0.0 3.3 3 1 0 4 4 4 0 CLASP N terminal Cnd3 PF12719.7 OAJ25050.1 - 0.11 11.7 0.9 3.5 6.7 0.3 3.2 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pex14_N PF04695.13 OAJ25051.1 - 3.6e-26 92.7 0.0 3.6e-26 92.7 0.0 3.8 3 1 0 4 4 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NPV_P10 PF05531.12 OAJ25051.1 - 0.00036 20.9 5.7 0.033 14.6 0.4 3.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 OAJ25051.1 - 0.00044 20.3 16.4 0.0014 18.7 2.6 2.3 2 1 1 3 3 2 2 Laminin Domain II Atg14 PF10186.9 OAJ25051.1 - 0.0019 17.3 2.7 0.0033 16.6 2.7 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAJ25051.1 - 0.003 16.5 9.9 0.0046 15.9 9.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 OAJ25051.1 - 0.0041 17.6 3.8 0.0068 16.9 3.8 1.3 1 0 0 1 1 1 1 Fez1 DUF885 PF05960.11 OAJ25051.1 - 0.0046 16.7 1.7 0.006 16.3 1.7 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF4795 PF16043.5 OAJ25051.1 - 0.0056 16.3 5.2 0.0088 15.7 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Golgin_A5 PF09787.9 OAJ25051.1 - 0.0093 15.5 8.0 0.014 14.8 8.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 IFT57 PF10498.9 OAJ25051.1 - 0.015 14.3 4.8 0.013 14.5 3.1 1.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5314 PF17241.2 OAJ25051.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DLP_helical PF18709.1 OAJ25051.1 - 0.024 13.9 4.5 0.035 13.3 4.5 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain Baculo_PEP_C PF04513.12 OAJ25051.1 - 0.025 14.6 0.7 0.09 12.8 0.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRP36 PF06102.12 OAJ25051.1 - 0.027 14.4 6.3 0.046 13.7 6.3 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PI3K_P85_iSH2 PF16454.5 OAJ25051.1 - 0.029 14.0 3.9 0.045 13.3 3.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4835 PF16119.5 OAJ25051.1 - 0.033 13.3 1.0 0.049 12.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) DUF2968 PF11180.8 OAJ25051.1 - 0.034 13.8 10.4 0.071 12.7 10.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) BshC PF10079.9 OAJ25051.1 - 0.036 12.8 3.6 0.049 12.4 3.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PilJ PF13675.6 OAJ25051.1 - 0.043 13.8 5.8 0.17 11.9 4.0 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prominin PF05478.11 OAJ25051.1 - 0.075 11.0 1.0 0.1 10.5 1.0 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 OAJ25051.1 - 0.087 10.3 9.7 0.11 9.9 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin PF00804.25 OAJ25051.1 - 0.094 12.4 5.5 0.19 11.4 5.4 1.5 1 1 0 1 1 1 0 Syntaxin zf-C4H2 PF10146.9 OAJ25051.1 - 0.11 12.8 7.7 0.13 12.6 6.5 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein Mt_ATP-synt_D PF05873.12 OAJ25051.1 - 0.16 11.8 4.0 1.2 9.0 4.0 2.0 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF948 PF06103.11 OAJ25051.1 - 0.16 12.2 9.4 2 8.7 0.7 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CEP63 PF17045.5 OAJ25051.1 - 0.17 11.8 7.7 0.33 10.8 7.6 1.5 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa FlgN PF05130.12 OAJ25051.1 - 0.21 12.1 10.7 0.34 11.4 10.7 1.2 1 0 0 1 1 1 0 FlgN protein DUF1664 PF07889.12 OAJ25051.1 - 0.22 11.6 10.4 0.25 11.4 0.8 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAJ25051.1 - 0.31 10.3 3.7 0.46 9.7 3.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Osmo_CC PF08946.10 OAJ25051.1 - 0.32 11.3 7.1 2.1 8.7 3.4 2.6 1 1 1 2 2 2 0 Osmosensory transporter coiled coil AAA_13 PF13166.6 OAJ25051.1 - 0.34 9.5 4.4 0.48 9.0 4.4 1.1 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 OAJ25051.1 - 0.38 9.3 3.5 0.56 8.7 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A EzrA PF06160.12 OAJ25051.1 - 0.39 8.8 7.6 1.4 7.0 7.6 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CHIP_TPR_N PF18391.1 OAJ25051.1 - 0.41 11.4 5.8 0.46 11.3 3.6 2.1 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain BST2 PF16716.5 OAJ25051.1 - 0.49 11.0 8.1 1.2 9.8 3.1 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ISG65-75 PF11727.8 OAJ25051.1 - 0.5 9.5 6.0 0.88 8.7 6.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.10 OAJ25051.1 - 0.58 10.3 3.5 1 9.5 0.8 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TipAS PF07739.13 OAJ25051.1 - 0.64 10.6 6.8 0.55 10.8 3.4 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain APG6_N PF17675.1 OAJ25051.1 - 0.87 10.1 17.3 0.87 10.1 10.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 OAJ25051.1 - 1.1 9.4 8.2 19 5.5 3.7 2.9 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 CLZ PF16526.5 OAJ25051.1 - 1.2 9.6 10.5 6.2 7.2 2.8 3.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 OAJ25051.1 - 1.2 9.2 6.6 0.93 9.6 2.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.9 OAJ25051.1 - 1.2 9.8 4.4 2.6 8.8 4.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Cdh1_DBD_1 PF18196.1 OAJ25051.1 - 1.3 9.4 5.8 1.6 9.1 4.8 1.6 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 YabA PF06156.13 OAJ25051.1 - 1.7 9.4 5.6 17 6.1 1.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FTA4 PF13093.6 OAJ25051.1 - 1.7 8.5 9.2 4 7.3 8.0 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BLOC1_2 PF10046.9 OAJ25051.1 - 1.8 8.9 6.9 1.5 9.2 1.5 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 OAJ25051.1 - 1.8 7.8 11.2 3.5 6.9 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 OAJ25051.1 - 2 9.2 4.3 7.7 7.3 4.3 1.9 1 1 0 1 1 1 0 Occludin homology domain FUSC PF04632.12 OAJ25051.1 - 2.1 6.8 7.8 0.66 8.4 0.6 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 OAJ25051.1 - 2.1 8.4 12.6 34 4.5 12.4 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAJ25051.1 - 2.3 8.3 9.2 0.62 10.1 4.7 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 OAJ25051.1 - 2.3 8.7 8.2 0.61 10.6 2.5 2.2 1 1 1 2 2 2 0 Spectrin repeat CdvA PF18822.1 OAJ25051.1 - 2.4 8.0 9.3 1.2 9.0 5.5 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain UPF0242 PF06785.11 OAJ25051.1 - 3.1 7.8 9.7 4.9 7.2 9.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Serglycin PF04360.12 OAJ25051.1 - 3.8 7.5 12.0 0.05 13.6 4.6 1.6 2 0 0 2 2 1 0 Serglycin HIP1_clath_bdg PF16515.5 OAJ25051.1 - 5.5 7.7 12.2 31 5.2 11.9 2.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 OAJ25051.1 - 5.6 7.3 15.7 5.8 7.3 10.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 OAJ25051.1 - 7.4 6.6 10.5 12 6.0 5.6 2.9 1 1 2 3 3 3 0 Prefoldin subunit HALZ PF02183.18 OAJ25051.1 - 7.8 6.8 8.4 15 5.9 0.1 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper V-SNARE PF05008.15 OAJ25051.1 - 8 6.9 9.4 24 5.4 7.4 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus zf-primase PF09329.11 OAJ25053.1 - 1.3e-12 47.3 1.8 2.3e-12 46.5 1.8 1.4 1 0 0 1 1 1 1 Primase zinc finger Proteasome PF00227.26 OAJ25054.1 - 5.2e-33 114.1 0.0 8.2e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_1 PF00561.20 OAJ25060.1 - 2.6e-21 76.4 0.0 8.8e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ25060.1 - 4.9e-14 52.3 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAJ25060.1 - 0.067 12.5 0.0 3.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Erp_C PF06780.11 OAJ25060.1 - 0.18 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Erp protein C-terminus KilA-N PF04383.13 OAJ25062.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 KilA-N domain Bac_rhodopsin PF01036.18 OAJ25063.1 - 6.1e-50 169.9 20.3 8e-50 169.5 20.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein AgrB PF04647.15 OAJ25063.1 - 0.0099 15.2 1.3 0.0099 15.2 1.3 1.8 2 0 0 2 2 2 1 Accessory gene regulator B Heliorhodopsin PF18761.1 OAJ25063.1 - 0.038 13.3 10.5 0.011 15.1 7.2 1.7 1 1 0 1 1 1 0 Heliorhodopsin Arteri_Gl PF00951.18 OAJ25063.1 - 0.97 9.2 5.6 0.16 11.7 1.3 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4131 PF13567.6 OAJ25063.1 - 1.2 8.7 7.8 1.5 8.5 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF2754 PF10953.8 OAJ25063.1 - 9.5 6.5 7.9 10 6.4 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) zf-CCHC_3 PF13917.6 OAJ25064.1 - 1.2e-07 31.6 3.9 2.6e-07 30.5 3.9 1.6 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 OAJ25064.1 - 3.1 6.0 8.7 3.9 5.7 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC14 PF08045.11 OAJ25065.1 - 9.8e-09 34.7 3.7 0.00078 18.6 1.2 2.8 2 1 0 2 2 2 2 Cell division control protein 14, SIN component TPR_1 PF00515.28 OAJ25066.1 - 5.9e-09 35.4 0.2 3.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ25066.1 - 1.2e-05 25.1 0.3 0.2 11.8 0.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAJ25066.1 - 0.0016 18.5 0.2 0.0073 16.4 0.1 2.2 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OAJ25066.1 - 0.015 15.5 1.1 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ25066.1 - 0.038 14.4 0.1 3.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ25066.1 - 0.13 12.4 0.4 2.5 8.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ25066.1 - 0.14 13.1 0.8 44 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 OAJ25067.1 - 2.8e-45 154.2 0.0 5.1e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ25067.1 - 1.2e-31 109.3 0.0 2.1e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAJ25067.1 - 0.0059 15.4 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OAJ25067.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Acyltransferase PF01553.21 OAJ25068.1 - 1e-14 54.3 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase MOSC PF03473.17 OAJ25069.1 - 1.5e-18 67.1 0.0 2.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAJ25069.1 - 5.5e-08 32.7 0.0 0.00027 20.8 0.0 2.7 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OAJ25069.1 - 7.5e-08 31.7 0.0 3.8e-06 26.1 0.0 3.1 2 1 0 2 2 2 1 Aminotransferase class-V AAA PF00004.29 OAJ25070.1 - 3.5e-27 95.4 0.0 3.9e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ25070.1 - 0.00091 19.5 0.1 0.1 12.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ25070.1 - 0.0078 16.6 0.0 0.0097 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OAJ25070.1 - 0.015 15.1 0.1 0.016 15.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ25070.1 - 0.016 14.9 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ25070.1 - 0.017 15.5 0.1 0.022 15.1 0.1 1.5 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 OAJ25070.1 - 0.018 15.0 0.1 0.05 13.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAJ25070.1 - 0.019 15.2 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAJ25070.1 - 0.022 14.1 0.0 0.05 13.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAJ25070.1 - 0.027 13.7 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 OAJ25070.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 OAJ25070.1 - 0.054 13.1 0.1 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 OAJ25070.1 - 0.12 12.0 0.0 7.6 6.1 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 OAJ25070.1 - 0.18 12.1 0.1 0.37 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain SKN1 PF03935.15 OAJ25071.1 - 2.9e-176 586.8 1.8 3.3e-176 586.6 1.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Phage_integrase PF00589.22 OAJ25073.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family GST_N PF02798.20 OAJ25074.1 - 2.9e-13 50.0 0.3 8.5e-13 48.5 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ25074.1 - 6.2e-10 39.2 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ25074.1 - 9.7e-10 38.7 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ25074.1 - 6.3e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ25074.1 - 6.9e-07 29.2 0.1 1.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ25074.1 - 2.5e-05 24.4 0.0 6.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ25074.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RT_RNaseH PF17917.1 OAJ25075.1 - 2.2e-12 47.2 0.0 3.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ25075.1 - 2.1e-06 27.7 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop53 PF07767.11 OAJ25076.1 - 0.066 12.6 12.5 0.08 12.3 12.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRN3 PF05327.11 OAJ25076.1 - 3.5 6.1 5.7 4.3 5.8 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDE_Tnp_4 PF13359.6 OAJ25077.1 - 7e-18 64.8 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ25077.1 - 0.0042 16.8 1.0 0.066 12.9 0.0 3.0 4 0 0 4 4 4 1 Transposase DDE domain Herpes_UL42 PF02282.16 OAJ25077.1 - 0.045 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) ATG22 PF11700.8 OAJ25078.1 - 8.4e-122 407.2 20.1 1e-121 406.9 20.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like ORC_WH_C PF18137.1 OAJ25079.1 - 0.91 9.6 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Methyltransf_33 PF10017.9 OAJ25080.1 - 1.3e-63 215.0 0.0 7.6e-52 176.4 0.0 2.3 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAJ25080.1 - 2.6e-17 63.3 1.7 4.4e-17 62.5 0.2 2.0 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAJ25080.1 - 5.3e-05 23.7 2.6 0.00013 22.4 0.9 2.6 3 0 0 3 3 3 1 DinB superfamily DUF2076 PF09849.9 OAJ25081.1 - 4e-05 23.8 26.4 0.00014 22.0 26.4 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAJ25081.1 - 0.006 16.7 4.9 0.01 15.9 4.9 1.4 1 0 0 1 1 1 1 CHCH domain RskA PF10099.9 OAJ25081.1 - 0.037 14.3 10.2 0.046 14.0 10.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Utp21 PF04192.12 OAJ25081.1 - 0.069 12.6 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain CX9C PF16860.5 OAJ25081.1 - 0.093 12.8 1.7 0.16 12.0 1.7 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAJ25081.1 - 0.35 10.9 2.3 18 5.4 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 OAJ25081.1 - 0.35 11.3 2.7 1.9 8.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Aa_trans PF01490.18 OAJ25082.1 - 4.1e-82 276.1 32.2 5.1e-82 275.8 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PTPRCAP PF15713.5 OAJ25082.1 - 0.00071 19.9 0.5 0.0012 19.1 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Ctr PF04145.15 OAJ25082.1 - 0.0073 16.9 0.0 0.44 11.2 0.0 2.7 2 0 0 2 2 2 1 Ctr copper transporter family FAM176 PF14851.6 OAJ25082.1 - 0.39 10.4 1.1 0.8 9.4 1.1 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OAJ25082.1 - 1.6 6.9 3.1 2.3 6.4 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ25082.1 - 1.9 7.7 4.4 2.7 7.2 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 OAJ25085.1 - 3.9e-64 216.6 0.0 3.9e-64 216.6 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25085.1 - 2.7e-43 148.1 0.3 7.3e-43 146.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ25085.1 - 1.7e-06 27.5 0.0 2.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like HNOBA PF07701.14 OAJ25085.1 - 0.008 15.6 0.9 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Heme NO binding associated Pkinase_fungal PF17667.1 OAJ25085.1 - 0.043 12.6 0.0 0.043 12.6 0.0 3.4 3 0 0 3 3 3 0 Fungal protein kinase Spt20 PF12090.8 OAJ25085.1 - 0.13 11.9 61.5 0.53 9.9 17.6 2.6 2 0 0 2 2 2 0 Spt20 family DUF4770 PF15994.5 OAJ25085.1 - 1.7 8.8 19.2 0.84 9.9 6.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Spore_YhcN_YlaJ PF09580.10 OAJ25085.1 - 3.6 7.6 20.4 0.24 11.5 2.3 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Vps39_2 PF10367.9 OAJ25086.1 - 3.6e-06 27.4 0.9 8.1e-06 26.2 0.9 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAJ25086.1 - 8.9e-06 25.5 0.0 4e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 OAJ25086.1 - 0.086 13.1 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 OAJ25086.1 - 2.4 9.2 10.2 71 4.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HAD PF12710.7 OAJ25087.1 - 4.4e-21 76.2 0.0 5.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 OAJ25087.1 - 4.3e-06 26.4 0.0 2.2e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 OAJ25087.1 - 0.00015 21.3 0.3 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 OAJ25087.1 - 0.00081 19.7 0.7 0.014 15.7 0.0 2.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 OAJ25088.1 - 2.1e-36 126.3 0.5 3e-36 125.8 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ25088.1 - 0.0017 18.8 0.1 0.0033 17.8 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 OAJ25088.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PLA2_B PF01735.18 OAJ25089.1 - 1.3e-136 455.9 1.6 1.5e-136 455.7 1.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 OAJ25089.1 - 3.1e-05 24.2 1.9 0.00013 22.2 1.9 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase XPG_N PF00752.17 OAJ25090.1 - 6.6e-30 103.6 0.0 1.3e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ25090.1 - 3.8e-27 94.5 0.0 1.1e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region HHH_5 PF14520.6 OAJ25090.1 - 0.091 13.4 0.0 0.58 10.8 0.0 2.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain NDUF_B8 PF05821.11 OAJ25091.1 - 3.2e-09 36.9 0.2 9.8e-09 35.3 0.2 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF4380 PF14315.6 OAJ25091.1 - 0.027 13.4 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) SR-25 PF10500.9 OAJ25091.1 - 2.5 7.7 6.1 3.5 7.2 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cnd2 PF05786.14 OAJ25093.1 - 5.1e-156 521.5 0.0 1.6e-126 424.0 0.0 5.0 2 1 2 4 4 4 2 Condensin complex subunit 2 DUF4152 PF13680.6 OAJ25093.1 - 2e-05 24.1 0.1 3.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4152) CNDH2_N PF06278.11 OAJ25093.1 - 0.14 12.4 1.0 0.95 9.7 0.0 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal GCFC PF07842.12 OAJ25094.1 - 2.7e-66 224.0 14.3 3.8e-66 223.5 14.3 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAJ25094.1 - 8.5e-08 32.0 0.2 8.5e-08 32.0 0.2 2.6 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 OAJ25094.1 - 0.00081 19.4 0.3 0.00081 19.4 0.3 4.1 4 1 1 5 5 5 1 G-patch domain p450 PF00067.22 OAJ25095.1 - 2.2e-49 168.5 0.0 4.5e-48 164.2 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 TatD_DNase PF01026.21 OAJ25096.1 - 1e-49 169.3 0.0 1.5e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Birna_VP4 PF01768.16 OAJ25097.1 - 0.26 11.0 2.0 0.18 11.6 0.4 1.5 2 0 0 2 2 2 0 Birnavirus VP4 protein Fer2_4 PF13510.6 OAJ25098.1 - 3.7e-19 68.5 0.1 1.2e-18 66.9 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 OAJ25098.1 - 4.9e-15 54.8 0.1 4.9e-15 54.8 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region WD40 PF00400.32 OAJ25098.1 - 9.1e-15 54.8 0.9 9.1e-07 29.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Fer2 PF00111.27 OAJ25098.1 - 4.4e-08 33.0 1.5 6.4e-08 32.4 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain ANAPC4_WD40 PF12894.7 OAJ25098.1 - 4.2e-05 23.7 0.0 0.4 11.0 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Molybdopterin PF00384.22 OAJ25098.1 - 0.00063 18.8 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase His_Phos_1 PF00300.22 OAJ25099.1 - 2.5e-17 63.2 0.7 1.1e-09 38.3 0.3 4.4 3 1 1 4 4 4 4 Histidine phosphatase superfamily (branch 1) FDF PF09532.10 OAJ25100.1 - 6.7e-08 33.4 0.0 6.7e-08 33.4 0.0 3.3 5 0 0 5 5 5 1 FDF domain LSM14 PF12701.7 OAJ25100.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain Molybdopterin PF00384.22 OAJ25101.1 - 5.1e-72 243.2 0.0 1.7e-36 126.2 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 OAJ25101.1 - 2.1e-14 53.9 0.1 5.3e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal TPP_enzyme_M PF00205.22 OAJ25101.1 - 0.0033 17.2 0.1 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DNA_pol_E_B PF04042.16 OAJ25102.1 - 2.2e-47 161.1 0.2 3e-47 160.7 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FleQ PF06490.11 OAJ25102.1 - 0.084 13.3 0.0 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ UPF0270 PF06794.12 OAJ25102.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Zn_clus PF00172.18 OAJ25103.1 - 1.3e-11 44.4 7.1 2.2e-11 43.7 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOPS PF08075.11 OAJ25107.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.2 3 0 0 3 3 3 0 NOPS (NUC059) domain CENP-C_C PF11699.8 OAJ25109.1 - 1.2e-27 95.9 0.3 2.2e-27 95.1 0.3 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 OAJ25109.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DTHCT PF08070.11 OAJ25109.1 - 0.02 15.6 1.4 0.02 15.6 1.4 5.8 5 1 1 6 6 6 0 DTHCT (NUC029) region Flavi_NS2B PF01002.19 OAJ25110.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Exo_endo_phos_2 PF14529.6 OAJ25111.1 - 4.1e-07 29.9 0.0 9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ25111.1 - 0.015 14.8 1.4 0.015 14.8 1.4 1.7 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family SOG2 PF10428.9 OAJ25111.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RVT_1 PF00078.27 OAJ25112.1 - 3.4e-23 82.3 0.0 4.4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF1_Zn_bind PF09416.10 OAJ25114.1 - 2.5e-71 238.6 7.2 2.5e-71 238.6 7.2 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OAJ25114.1 - 1e-58 198.3 0.0 2.8e-58 196.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAJ25114.1 - 1.7e-50 172.3 3.3 4.2e-29 102.1 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OAJ25114.1 - 1.4e-33 114.9 0.0 3e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OAJ25114.1 - 6.7e-13 48.8 0.0 3.1e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ25114.1 - 2.2e-10 41.0 0.0 7.1e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ25114.1 - 1.9e-05 24.5 0.9 0.29 10.8 0.0 3.4 2 1 2 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAJ25114.1 - 2.4e-05 24.4 0.0 6.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OAJ25114.1 - 5.4e-05 22.6 0.4 0.0026 17.0 0.1 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OAJ25114.1 - 0.00031 20.6 0.1 0.0011 18.8 0.1 2.0 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 OAJ25114.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 OAJ25114.1 - 0.022 13.9 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 OAJ25114.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OAJ25114.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 OAJ25114.1 - 0.096 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA PF00004.29 OAJ25114.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OAJ25114.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein KDZ PF18758.1 OAJ25118.1 - 3.6e-49 167.4 0.0 5.7e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 OAJ25118.1 - 0.11 12.7 0.2 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases RasGEF PF00617.19 OAJ25119.1 - 1.4e-40 139.4 0.0 3e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ25119.1 - 6.5e-10 39.2 0.4 1.5e-09 38.0 0.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Acyl-CoA_dh_2 PF08028.11 OAJ25120.1 - 4e-09 36.8 0.0 7.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ25120.1 - 1.2e-05 25.9 0.1 2.6e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ25120.1 - 0.0026 17.9 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ25120.1 - 0.013 15.7 1.0 0.031 14.5 0.1 2.1 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ADH_zinc_N PF00107.26 OAJ25121.1 - 1.2e-08 35.0 0.0 6.2e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ25121.1 - 1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ25121.1 - 0.00034 20.5 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAJ25121.1 - 0.018 16.1 0.0 0.035 15.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.16 OAJ25121.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 OAJ25122.1 - 6.9e-36 123.5 0.2 1.4e-35 122.6 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ25122.1 - 7.4e-29 101.0 0.6 1e-28 100.5 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ25122.1 - 5.5e-09 36.2 0.2 9.6e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Bac_luciferase PF00296.20 OAJ25124.1 - 0.76 9.1 7.7 0.34 10.3 3.0 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase Med15 PF09606.10 OAJ25125.1 - 0.00036 19.4 17.6 0.00072 18.4 17.5 1.5 1 1 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Gly_transf_sug PF04488.15 OAJ25126.1 - 2.4e-20 73.0 0.1 4e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAJ25126.1 - 0.047 13.0 0.6 1.6 7.9 0.5 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DSS1_SEM1 PF05160.13 OAJ25127.1 - 6.4e-18 64.6 14.3 4e-17 62.0 14.3 2.0 1 1 0 1 1 1 1 DSS1/SEM1 family Myb_DNA-binding PF00249.31 OAJ25128.1 - 2.9e-11 43.4 0.0 9.7e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OAJ25128.1 - 9.9e-11 41.8 0.0 4.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 OAJ25128.1 - 1.3e-08 34.5 5.4 2.1e-08 33.8 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OAJ25128.1 - 1.8e-06 28.1 0.0 5.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SAM_decarbox PF01536.16 OAJ25131.1 - 1.4e-115 386.2 0.0 2e-115 385.6 0.0 1.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase LSM PF01423.22 OAJ25132.1 - 1.3e-18 66.4 0.4 1.9e-18 65.9 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAJ25132.1 - 0.014 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Hfq protein 60KD_IMP PF02096.20 OAJ25133.1 - 5.9e-09 36.0 0.0 0.002 18.1 0.0 2.5 2 1 0 2 2 2 2 60Kd inner membrane protein Peptidase_S10 PF00450.22 OAJ25138.1 - 4.2e-70 237.3 0.0 6.3e-70 236.7 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 OAJ25140.1 - 2.4e-71 241.4 0.1 2.9e-71 241.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PLU-1 PF08429.11 OAJ25141.1 - 1.1e-47 162.8 1.7 1.9e-47 162.1 1.7 1.4 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 OAJ25141.1 - 2.3e-42 144.0 0.4 4.7e-42 143.0 0.4 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 OAJ25141.1 - 3.4e-22 78.1 45.2 1.5e-12 47.2 3.2 4.5 4 0 0 4 4 4 4 PHD-finger ARID PF01388.21 OAJ25141.1 - 2.9e-17 63.1 0.0 7.2e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 OAJ25141.1 - 7.8e-13 48.6 0.2 7.8e-13 48.6 0.2 3.1 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 OAJ25141.1 - 2.1e-12 46.8 1.1 4.2e-12 45.8 1.1 1.6 1 0 0 1 1 1 1 jmjN domain TIM PF00121.18 OAJ25142.1 - 3.5e-92 308.2 0.2 4e-92 308.0 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 OAJ25142.1 - 0.0086 15.6 0.2 0.099 12.1 0.0 2.0 1 1 1 2 2 2 1 CutC family MEDS PF14417.6 OAJ25142.1 - 0.071 12.9 0.1 0.18 11.6 0.1 1.7 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain INO80_Ies4 PF08193.11 OAJ25143.1 - 0.00044 20.3 0.6 0.00044 20.3 0.6 3.8 2 2 2 4 4 4 1 INO80 complex subunit Ies4 Mis12 PF05859.12 OAJ25144.1 - 6.8e-25 87.7 0.3 1.5e-24 86.6 0.3 1.6 1 1 0 1 1 1 1 Mis12 protein Cyclin_N PF00134.23 OAJ25145.1 - 1.7e-09 37.5 0.0 1.8e-07 30.9 0.0 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OAJ25145.1 - 0.051 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin C-terminal domain Pyr_redox_2 PF07992.14 OAJ25146.1 - 0.00025 20.4 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 OAJ25146.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Pyr_redox PF00070.27 OAJ25146.1 - 0.079 13.5 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ25146.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TauE PF01925.19 OAJ25146.1 - 4.9 6.7 8.3 0.17 11.5 1.7 1.7 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Myb_DNA-binding PF00249.31 OAJ25147.1 - 3.4e-16 59.1 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ25147.1 - 7.4e-12 45.3 0.0 6.6e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop16 PF09420.10 OAJ25147.1 - 0.04 13.9 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 SLIDE PF09111.10 OAJ25147.1 - 0.25 11.4 0.0 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 SLIDE Phos_pyr_kin PF08543.12 OAJ25148.1 - 6.4e-09 35.6 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAJ25148.1 - 8.6e-06 25.3 0.0 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase NUMOD3 PF07460.11 OAJ25148.1 - 0.058 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) OrfB_Zn_ribbon PF07282.11 OAJ25149.1 - 1.2e-12 47.6 0.1 2.4e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 OAJ25149.1 - 9.3e-10 37.8 0.3 2.4e-09 36.6 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 OAJ25149.1 - 7.3e-05 23.0 0.1 0.00022 21.4 0.1 1.8 1 0 0 1 1 1 1 Probable transposase Chorismate_synt PF01264.21 OAJ25150.1 - 0.00029 19.7 0.0 0.00035 19.4 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase FAM153 PF15722.5 OAJ25150.1 - 0.084 13.2 0.4 0.14 12.5 0.4 1.4 1 0 0 1 1 1 0 FAM153 family NAD_binding_2 PF03446.15 OAJ25151.1 - 3.3e-52 176.8 0.0 4.3e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 OAJ25151.1 - 5.7e-48 163.8 0.0 8.1e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 OAJ25151.1 - 0.0045 17.5 0.1 0.0076 16.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 OAJ25151.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CoatB PF10389.9 OAJ25151.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B OrfB_Zn_ribbon PF07282.11 OAJ25152.1 - 9.9e-05 22.2 1.6 0.0035 17.2 1.6 2.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain BORCS8 PF10167.9 OAJ25152.1 - 0.017 15.1 1.1 0.028 14.3 0.2 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF3932 PF13068.6 OAJ25152.1 - 0.024 14.9 0.1 3.1 8.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) MIP PF00230.20 OAJ25155.1 - 8.1e-41 140.2 13.4 1.1e-40 139.8 13.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Metallophos PF00149.28 OAJ25156.1 - 4.4e-37 128.6 0.1 6.9e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAJ25156.1 - 0.0042 16.7 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 OAJ25156.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OAJ25156.1 - 0.24 10.7 0.0 0.35 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) DUF155 PF02582.14 OAJ25157.1 - 1.1e-46 159.2 0.0 1.6e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Helo_like_N PF17111.5 OAJ25157.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Gpr1_Fun34_YaaH PF01184.19 OAJ25158.1 - 4.6e-83 277.9 18.4 5.6e-83 277.6 18.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 6PGD PF00393.19 OAJ25159.1 - 2.3e-13 50.2 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain DUF1793 PF08760.11 OAJ25159.1 - 5e-05 23.8 0.1 0.00015 22.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) NAD_binding_2 PF03446.15 OAJ25159.1 - 0.04 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAJ25159.1 - 0.079 13.2 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Cgr1 PF03879.14 OAJ25160.1 - 5.6e-15 55.6 23.6 6.1e-15 55.5 23.6 1.0 1 0 0 1 1 1 1 Cgr1 family Titin_Z PF09042.11 OAJ25160.1 - 0.5 10.4 6.6 0.16 11.9 1.4 2.4 1 1 1 2 2 2 0 Titin Z PEARLI-4 PF05278.12 OAJ25160.1 - 2 8.0 11.6 2.3 7.7 11.6 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Atg14 PF10186.9 OAJ25162.1 - 2.1e-14 53.4 6.3 1.6e-08 34.0 0.0 3.6 3 1 0 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA PF03153.13 OAJ25162.1 - 0.25 11.3 1.4 0.45 10.5 1.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit E1_dh PF00676.20 OAJ25163.1 - 1.5e-85 286.7 0.0 1.9e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAJ25163.1 - 0.23 10.7 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase AAA PF00004.29 OAJ25164.1 - 5.3e-41 140.1 0.0 8.5e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ25164.1 - 1.2e-10 41.1 0.1 2.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAJ25164.1 - 1.8e-10 40.4 0.1 3.5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ25164.1 - 1.2e-05 25.6 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OAJ25164.1 - 2.3e-05 23.7 0.0 6.1e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAJ25164.1 - 3.9e-05 23.9 0.4 0.033 14.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 OAJ25164.1 - 0.00043 20.7 0.4 0.0096 16.3 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ25164.1 - 0.00069 19.6 0.4 0.0059 16.6 0.3 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ25164.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 OAJ25164.1 - 0.0014 18.2 0.7 0.0044 16.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 OAJ25164.1 - 0.0051 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ25164.1 - 0.0054 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAJ25164.1 - 0.006 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAJ25164.1 - 0.0061 15.9 0.1 0.22 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_14 PF13173.6 OAJ25164.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ25164.1 - 0.023 14.3 0.6 2.6 7.6 0.1 2.5 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ25164.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAJ25164.1 - 0.043 13.0 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 OAJ25164.1 - 0.086 13.1 0.3 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ25164.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 OAJ25164.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OAJ25164.1 - 0.13 12.1 0.2 0.79 9.6 0.1 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 OAJ25164.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ25164.1 - 0.26 11.0 2.3 0.36 10.5 0.3 2.1 2 1 0 2 2 2 0 AAA domain NUDIX PF00293.28 OAJ25165.1 - 1.4e-15 57.5 0.0 5.3e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain DUF1770 PF08589.10 OAJ25166.1 - 0.00092 20.1 0.1 0.00092 20.1 0.1 2.2 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) AWS PF17907.1 OAJ25167.1 - 0.36 10.9 5.5 0.33 11.0 2.2 2.1 2 0 0 2 2 2 0 AWS domain zf-met PF12874.7 OAJ25167.1 - 0.62 10.5 0.1 0.62 10.5 0.1 2.6 2 1 1 3 3 3 0 Zinc-finger of C2H2 type DUF3915 PF13054.6 OAJ25168.1 - 0.026 14.5 6.4 0.038 14.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) eIF3_subunit PF08597.10 OAJ25168.1 - 0.076 12.9 9.3 0.096 12.6 9.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit STAG PF08514.11 OAJ25168.1 - 0.16 11.9 2.8 0.12 12.2 1.4 1.5 1 1 0 1 1 1 0 STAG domain DUF4337 PF14235.6 OAJ25168.1 - 0.4 10.8 2.8 0.5 10.5 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Conotoxin PF02950.17 OAJ25168.1 - 0.47 11.5 2.0 1 10.5 0.8 2.0 1 1 1 2 2 2 0 Conotoxin Connexin PF00029.19 OAJ25168.1 - 0.51 10.1 1.4 0.57 9.9 1.4 1.1 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 OAJ25168.1 - 0.77 8.9 9.9 0.94 8.6 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3824 PF12868.7 OAJ25168.1 - 4.6 7.9 17.4 5.8 7.6 9.8 2.0 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Presenilin PF01080.17 OAJ25168.1 - 6.4 5.4 6.9 6.9 5.3 6.9 1.1 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 OAJ25168.1 - 7 4.8 26.6 1.2 7.4 23.2 1.4 1 1 0 1 1 1 0 Atrophin-1 family Whi5 PF08528.11 OAJ25169.1 - 3e-09 36.3 0.0 4.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Fringe PF02434.16 OAJ25170.1 - 2.4e-08 33.8 0.0 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PGP_phosphatase PF09419.10 OAJ25171.1 - 1.5e-39 135.3 0.0 7.1e-35 120.1 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OAJ25171.1 - 0.077 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like FAD_binding_3 PF01494.19 OAJ25172.1 - 2.5e-16 59.9 4.3 8.4e-07 28.5 0.3 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 OAJ25172.1 - 0.00086 19.0 0.0 0.0022 17.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ25172.1 - 0.0059 15.7 7.3 0.15 11.1 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ25172.1 - 0.007 16.6 0.2 0.028 14.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ25172.1 - 0.031 14.8 0.1 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAJ25172.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 OAJ25172.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAJ25172.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DDE_3 PF13358.6 OAJ25174.1 - 7.7e-28 97.1 0.0 1.3e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ25174.1 - 0.00056 20.5 0.0 0.0017 18.9 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OAJ25174.1 - 0.0079 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.6 OAJ25174.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix FTHFS PF01268.19 OAJ25176.1 - 9.1e-250 829.6 0.1 2.1e-249 828.4 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAJ25176.1 - 6.4e-63 210.9 0.9 6.4e-63 210.9 0.9 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAJ25176.1 - 1.6e-31 108.9 0.1 4.1e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain F-box PF00646.33 OAJ25176.1 - 0.00031 20.5 0.4 0.00067 19.5 0.4 1.5 1 0 0 1 1 1 1 F-box domain MHB PF16525.5 OAJ25177.1 - 0.035 14.3 0.0 4 7.8 0.0 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding NDT80_PhoG PF05224.12 OAJ25178.1 - 2e-11 44.5 0.0 1.5e-10 41.6 0.0 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family 2-oxoacid_dh PF00198.23 OAJ25180.1 - 2.8e-79 265.8 0.0 4.6e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ25180.1 - 9.4e-19 67.0 1.7 1.8e-18 66.1 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ25180.1 - 0.00011 22.0 0.0 0.073 12.9 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 OAJ25180.1 - 0.0015 19.2 0.0 0.66 10.7 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 OAJ25180.1 - 0.014 15.3 0.5 0.028 14.3 0.5 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HSF_DNA-bind PF00447.17 OAJ25181.1 - 8.2e-31 106.5 0.5 1.4e-30 105.7 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 OAJ25181.1 - 1.2e-24 86.6 0.1 2.4e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain RMI1_N PF08585.12 OAJ25181.1 - 0.055 13.2 0.5 0.098 12.4 0.5 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Bromodomain PF00439.25 OAJ25182.1 - 1.3e-14 54.0 0.1 3.1e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Bromodomain CBM_6 PF03422.15 OAJ25182.1 - 0.033 14.5 1.5 0.53 10.6 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) LMF1 PF06762.14 OAJ25182.1 - 0.26 10.4 0.0 0.38 9.8 0.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor SCAMP PF04144.13 OAJ25183.1 - 6.9e-48 163.2 3.8 8.2e-48 163.0 3.8 1.1 1 0 0 1 1 1 1 SCAMP family SAE2 PF08573.10 OAJ25183.1 - 0.064 14.4 0.2 0.1 13.7 0.2 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Phage_holin_2_4 PF16082.5 OAJ25183.1 - 0.13 12.0 0.2 0.35 10.6 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3958 PF13125.6 OAJ25183.1 - 0.71 10.1 4.8 9.1 6.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) SAM_2 PF07647.17 OAJ25184.1 - 1.1e-08 35.0 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ25184.1 - 8.5e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 OAJ25184.1 - 0.068 13.4 0.6 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) Ank_4 PF13637.6 OAJ25185.1 - 6.7e-14 52.1 0.0 9.4e-08 32.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ25185.1 - 8.2e-12 44.2 0.0 0.0005 20.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAJ25185.1 - 6.7e-11 42.6 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ25185.1 - 2.7e-10 40.3 0.3 9.2e-08 32.2 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAJ25185.1 - 1.8e-08 34.4 0.0 0.0028 18.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat SMC_N PF02463.19 OAJ25186.1 - 5.3e-66 222.2 32.9 9.6e-65 218.1 32.9 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ25186.1 - 2.4e-24 85.9 0.0 7e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ25186.1 - 1.3e-12 48.7 4.0 1.3e-12 48.7 4.0 7.3 3 2 3 7 7 2 1 AAA domain AAA_21 PF13304.6 OAJ25186.1 - 7.6e-11 42.4 12.9 1.8e-05 24.8 0.0 4.0 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ25186.1 - 0.0001 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 OAJ25186.1 - 0.00086 17.0 29.6 0.00086 17.0 29.6 4.5 4 1 0 4 4 3 1 Protein of unknown function (DUF3584) Img2 PF05046.14 OAJ25186.1 - 0.064 13.6 3.5 0.5 10.7 0.8 3.3 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Baculo_PEP_C PF04513.12 OAJ25186.1 - 0.12 12.4 15.4 0.21 11.7 0.5 4.9 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SpoOE-like PF09388.10 OAJ25186.1 - 0.39 10.6 9.7 0.13 12.2 0.2 4.4 4 0 0 4 4 4 0 Spo0E like sporulation regulatory protein PKcGMP_CC PF16808.5 OAJ25186.1 - 0.68 9.8 16.8 0.2 11.5 0.3 6.2 5 1 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran PF00005.27 OAJ25186.1 - 1 9.9 0.0 1 9.9 0.0 6.3 4 2 0 5 5 4 0 ABC transporter Thiolase_N PF00108.23 OAJ25187.1 - 3.4e-79 265.9 2.3 4.5e-79 265.5 2.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ25187.1 - 4.9e-49 165.1 0.5 1.2e-48 163.8 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ25187.1 - 0.00016 21.3 1.7 0.00045 19.9 1.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain RVT_2 PF07727.14 OAJ25190.1 - 1e-60 205.4 0.0 1.5e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ25190.1 - 1.6e-12 47.7 0.2 1.2e-11 44.8 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.6 OAJ25190.1 - 0.086 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain GTP_cyclohydroI PF01227.22 OAJ25191.1 - 4.6e-75 251.0 0.1 7.6e-75 250.3 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OAJ25191.1 - 0.002 18.3 0.0 0.0072 16.5 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 OAJ25191.1 - 0.04 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Abhydrolase_1 PF00561.20 OAJ25192.1 - 6.9e-17 61.9 1.5 2.4e-13 50.3 0.3 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ25192.1 - 3.6e-11 42.8 0.0 6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ25192.1 - 1.2e-10 42.4 1.8 1.2e-10 42.4 1.8 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 OAJ25192.1 - 7.6e-05 21.5 0.0 9.9e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 OAJ25192.1 - 7.9e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAJ25192.1 - 0.005 16.7 0.0 0.049 13.4 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Endosulfine PF04667.17 OAJ25193.1 - 3.3e-23 81.6 0.1 8.3e-23 80.3 0.1 1.7 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Zn_clus PF00172.18 OAJ25194.1 - 4.7e-07 29.8 9.1 8e-07 29.1 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ25194.1 - 0.00042 19.4 0.4 0.013 14.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain CDC45 PF02724.14 OAJ25194.1 - 1.6 6.9 13.9 2.9 6.1 1.4 2.1 2 0 0 2 2 2 0 CDC45-like protein MFS_1 PF07690.16 OAJ25195.1 - 3.8e-29 101.7 46.4 5e-27 94.8 25.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_5 PF18160.1 OAJ25195.1 - 0.68 9.2 3.4 2.3 7.5 0.4 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 WD40 PF00400.32 OAJ25196.1 - 3.2e-18 65.7 2.5 1.5e-07 32.0 0.0 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.25 OAJ25196.1 - 3.9e-14 52.7 0.0 4.5e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25196.1 - 1.9e-07 30.7 0.0 0.00075 18.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 OAJ25196.1 - 9.7e-06 25.4 11.6 0.054 13.8 0.5 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OAJ25196.1 - 0.00022 21.5 0.2 1.3 9.4 0.0 3.5 2 0 0 2 2 2 2 HEAT repeats Cohesin_HEAT PF12765.7 OAJ25196.1 - 0.012 15.9 1.0 0.036 14.4 0.1 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion ANAPC4_WD40 PF12894.7 OAJ25196.1 - 0.017 15.4 0.0 2.2 8.6 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 OAJ25196.1 - 0.073 13.1 0.4 12 5.9 0.1 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 OAJ25196.1 - 0.22 10.5 0.0 0.41 9.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2_aberr PF17017.5 OAJ25198.1 - 0.2 11.8 1.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Aberrant zinc-finger Myb_DNA-bind_4 PF13837.6 OAJ25199.1 - 0.0076 16.6 0.2 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain KKLCAg1 PF15204.6 OAJ25199.1 - 8.4 6.6 7.2 0.95 9.6 0.5 2.6 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 PfkB PF00294.24 OAJ25200.1 - 3.7e-17 62.6 0.0 1.9e-12 47.1 0.0 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Retrotran_gag_2 PF14223.6 OAJ25202.1 - 2.6e-22 79.0 0.1 3.6e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ25202.1 - 6.7e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 OAJ25202.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Copper-fist PF00649.18 OAJ25202.1 - 0.082 12.4 0.2 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain RVP PF00077.20 OAJ25202.1 - 0.09 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ25202.1 - 0.51 10.5 3.4 1.3 9.2 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle HA2 PF04408.23 OAJ25203.1 - 3.3e-24 85.2 0.0 3.2e-23 82.1 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ25203.1 - 1.9e-13 50.6 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ25203.1 - 2.8e-10 40.5 0.3 2.9e-09 37.2 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ25203.1 - 2.5e-06 27.4 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ25203.1 - 0.0026 18.0 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ25203.1 - 0.018 15.4 0.6 0.54 10.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 OAJ25203.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Inhibitor_I53 PF11714.8 OAJ25203.1 - 8 6.7 7.3 1.2 9.4 1.8 2.5 2 0 0 2 2 2 0 Thrombin inhibitor Madanin ERG4_ERG24 PF01222.17 OAJ25204.1 - 1.7e-139 465.3 4.1 2e-139 465.1 4.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAJ25204.1 - 3.4e-05 23.5 0.1 7.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OAJ25204.1 - 0.00098 19.5 1.4 0.0026 18.1 0.0 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 OAJ25204.1 - 0.0037 17.7 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TMEM119 PF15724.5 OAJ25204.1 - 0.21 11.6 1.0 0.33 11.0 1.0 1.2 1 0 0 1 1 1 0 TMEM119 family DDE_3 PF13358.6 OAJ25205.1 - 7.5e-26 90.6 0.0 1.2e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ25205.1 - 5.7e-09 36.5 0.4 3.9e-06 27.4 0.3 2.9 2 0 0 2 2 2 2 Homeodomain-like domain HTH_33 PF13592.6 OAJ25205.1 - 7.4e-06 25.5 0.1 3.1e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.11 OAJ25205.1 - 0.036 13.0 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 OAJ25205.1 - 0.055 13.7 0.9 0.25 11.6 0.2 2.3 2 0 0 2 2 2 0 Transposase HTH_23 PF13384.6 OAJ25205.1 - 0.066 13.0 0.2 1.5 8.7 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 OAJ25205.1 - 0.074 13.1 0.3 2.1 8.5 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase RNase_II_C_S1 PF18614.1 OAJ25207.1 - 0.0025 17.7 0.2 0.0065 16.4 0.2 1.6 1 0 0 1 1 1 1 RNase II-type exonuclease C-terminal S1 domain DPM2 PF07297.12 OAJ25207.1 - 0.11 12.8 0.5 0.18 12.2 0.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BolA PF01722.18 OAJ25208.1 - 3.8e-12 46.3 0.0 1e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein GCD14 PF08704.10 OAJ25209.1 - 1.3e-72 244.5 2.9 1.1e-29 103.9 0.1 4.2 4 0 0 4 4 4 4 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OAJ25209.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sec39 PF08314.11 OAJ25210.1 - 0.24 9.8 0.3 0.39 9.1 0.3 1.3 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Mito_carr PF00153.27 OAJ25211.1 - 4.6e-25 87.4 4.0 6.2e-14 51.7 0.1 2.4 3 0 0 3 3 3 2 Mitochondrial carrier protein Ribosomal_S24e PF01282.19 OAJ25212.1 - 4.5e-32 109.8 0.1 7.9e-32 109.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e NUDIX PF00293.28 OAJ25213.1 - 7.8e-11 42.1 0.0 1.7e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain EF_assoc_1 PF08355.12 OAJ25214.1 - 0.021 14.4 0.5 0.5 10.0 0.2 2.2 2 0 0 2 2 2 0 EF hand associated Tctex-1 PF03645.13 OAJ25218.1 - 8.8e-11 42.0 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Totivirus_coat PF05518.11 OAJ25218.1 - 4 5.4 11.6 4.8 5.1 11.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Complex1_LYR PF05347.15 OAJ25219.1 - 6.8e-05 22.8 0.3 0.00013 22.0 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ25219.1 - 0.024 15.4 0.3 0.037 14.8 0.3 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Kelch_4 PF13418.6 OAJ25220.1 - 7.5e-20 70.7 0.5 9.8e-06 25.5 0.0 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ25220.1 - 3.1e-13 49.4 1.8 0.0006 19.7 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 OAJ25220.1 - 7.3e-12 45.1 3.5 0.00036 20.7 0.1 5.4 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.25 OAJ25220.1 - 5.1e-09 35.6 0.0 0.031 13.9 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OAJ25220.1 - 4.3e-08 33.2 15.0 0.77 10.1 0.1 6.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ25220.1 - 0.0026 17.7 0.0 6.9 6.8 0.0 4.7 5 0 0 5 5 5 1 Kelch motif RCR PF12273.8 OAJ25221.1 - 4.3e-05 24.1 5.2 9.9e-05 23.0 5.2 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.6 OAJ25221.1 - 4.4e-05 23.5 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 GRP PF07172.11 OAJ25221.1 - 0.0024 18.5 1.9 0.0052 17.4 1.9 1.5 1 1 0 1 1 1 1 Glycine rich protein family EphA2_TM PF14575.6 OAJ25221.1 - 0.0082 17.0 0.6 0.019 15.8 0.6 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 OAJ25221.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 TMEM9 DUF1180 PF06679.12 OAJ25221.1 - 0.014 15.8 1.4 0.014 15.8 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) SIT PF15330.6 OAJ25221.1 - 0.024 15.1 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Mid2 PF04478.12 OAJ25221.1 - 0.028 14.3 0.9 0.044 13.6 0.4 1.5 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 OAJ25221.1 - 0.04 13.4 0.2 0.059 12.8 0.2 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4834 PF16118.5 OAJ25221.1 - 0.045 14.7 0.7 0.1 13.6 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 OAJ25221.1 - 0.049 13.5 0.2 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 OAJ25221.1 - 0.067 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Epiglycanin_C PF14654.6 OAJ25221.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.6 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region CD34_antigen PF06365.12 OAJ25221.1 - 0.13 11.8 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Rhabdo_glycop PF00974.18 OAJ25221.1 - 0.42 9.0 4.3 0.19 10.1 0.6 1.9 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein LapA_dom PF06305.11 OAJ25221.1 - 0.52 10.2 6.9 0.88 9.4 4.6 2.0 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain CDP-OH_P_transf PF01066.21 OAJ25222.1 - 9.9e-16 58.3 0.2 9.9e-16 58.3 0.2 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 OAJ25223.1 - 4.2e-46 157.4 0.0 7.2e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25223.1 - 3.7e-43 147.7 0.0 5.2e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIF_alpha PF05793.12 OAJ25223.1 - 0.00011 21.0 17.3 0.00011 21.0 17.3 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) C1_1 PF00130.22 OAJ25223.1 - 0.00056 19.7 5.8 0.0011 18.8 5.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Haspin_kinase PF12330.8 OAJ25223.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.6 2 0 0 2 2 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ25223.1 - 0.012 14.5 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAJ25223.1 - 0.015 15.3 1.2 0.016 15.1 0.0 1.5 2 0 0 2 2 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ25223.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H PF13771.6 OAJ25223.1 - 0.067 13.5 2.0 0.18 12.1 2.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAJ25223.1 - 0.15 12.2 3.9 0.33 11.1 3.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Macoilin PF09726.9 OAJ25223.1 - 0.44 9.0 16.3 0.94 8.0 16.3 1.4 1 0 0 1 1 1 0 Macoilin family Rrn6 PF10214.9 OAJ25223.1 - 0.45 9.0 20.3 0.7 8.3 20.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MAP65_ASE1 PF03999.12 OAJ25223.1 - 0.88 8.2 15.3 1.4 7.6 15.3 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Paf1 PF03985.13 OAJ25223.1 - 1.9 7.4 18.5 3.5 6.5 18.5 1.4 1 0 0 1 1 1 0 Paf1 PHD PF00628.29 OAJ25223.1 - 2.1 8.3 6.8 4.4 7.3 6.8 1.5 1 0 0 1 1 1 0 PHD-finger DUF2956 PF11169.8 OAJ25223.1 - 2.1 8.6 11.8 5.5 7.2 11.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) SpoIIIAH PF12685.7 OAJ25223.1 - 2.4 7.9 15.9 0.26 11.1 10.4 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein PI3K_1B_p101 PF10486.9 OAJ25223.1 - 2.5 5.8 14.9 3.7 5.2 14.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LRIF1 PF15741.5 OAJ25223.1 - 3.1 6.2 17.4 4.7 5.6 17.4 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 FAM60A PF15396.6 OAJ25223.1 - 5.8 6.9 14.5 17 5.3 14.5 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 OAJ25223.1 - 6.4 6.4 18.9 8.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GREB1 PF15782.5 OAJ25223.1 - 7 3.6 14.0 9.6 3.2 14.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4638 PF15472.6 OAJ25223.1 - 7.5 6.2 11.8 14 5.3 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Cullin PF00888.22 OAJ25225.1 - 2.7e-191 637.4 0.0 3.5e-191 637.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ25225.1 - 1.9e-28 98.3 0.4 4.4e-28 97.1 0.4 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 OAJ25225.1 - 0.025 14.9 0.3 0.096 13.0 0.0 2.3 2 0 0 2 2 2 0 Penicillinase repressor TrmB PF01978.19 OAJ25225.1 - 0.027 14.4 0.2 0.97 9.4 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MIEAP PF16026.5 OAJ25225.1 - 0.063 13.5 0.6 3.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Mitochondria-eating protein TetR_C_29 PF17938.1 OAJ25225.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Phyto-Amp PF15438.6 OAJ25226.1 - 0.043 13.6 2.4 0.29 11.0 0.4 2.1 1 1 1 2 2 2 0 Antigenic membrane protein of phytoplasma PTR PF12789.7 OAJ25226.1 - 0.049 13.7 0.1 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 Phage tail repeat like DEAD_2 PF06733.15 OAJ25227.1 - 1.8e-49 167.8 0.2 1.3e-43 148.7 0.0 2.5 3 0 0 3 3 3 2 DEAD_2 Helicase_C_2 PF13307.6 OAJ25227.1 - 2e-44 151.8 0.0 4.2e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 OAJ25227.1 - 1.2e-42 145.8 0.9 4.4e-39 134.1 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 OAJ25227.1 - 0.00035 20.6 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ25227.1 - 0.021 14.6 0.0 2.8 7.7 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ25227.1 - 0.042 14.1 0.1 8 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain HECT PF00632.25 OAJ25228.1 - 8.1e-97 324.4 0.0 1.1e-96 324.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAJ25228.1 - 9.5e-35 118.4 13.1 1.1e-11 44.5 2.4 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 OAJ25228.1 - 3.7e-19 68.9 0.0 1e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain VanZ PF04892.12 OAJ25229.1 - 2.2e-07 31.6 2.0 3.2e-07 31.0 2.0 1.2 1 0 0 1 1 1 1 VanZ like family Serglycin PF04360.12 OAJ25229.1 - 1.1 9.2 4.9 58 3.6 5.1 2.5 2 0 0 2 2 2 0 Serglycin Integrase_H2C2 PF17921.1 OAJ25230.1 - 2e-14 53.4 0.0 4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ25230.1 - 5.3e-14 52.1 0.0 1.6e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-BED PF02892.15 OAJ25230.1 - 1.1e-06 28.5 0.6 2.2e-06 27.6 0.6 1.5 1 0 0 1 1 1 1 BED zinc finger rve PF00665.26 OAJ25230.1 - 7.8e-06 26.1 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DBD_Tnp_Mut PF03108.15 OAJ25230.1 - 0.00018 21.4 0.8 0.0031 17.5 0.2 2.6 2 0 0 2 2 2 1 MuDR family transposase RT_RNaseH PF17917.1 OAJ25230.1 - 0.0069 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4219 PF13961.6 OAJ25231.1 - 6.5e-06 25.7 0.1 1.1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 OAJ25231.1 - 0.00078 19.2 0.2 0.0015 18.3 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SPX PF03105.19 OAJ25231.1 - 0.61 9.9 3.8 1 9.2 3.8 1.3 1 0 0 1 1 1 0 SPX domain Ribosomal_S3Ae PF01015.18 OAJ25232.1 - 3.4e-89 297.8 0.4 3.9e-89 297.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 OAJ25232.1 - 0.16 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SET PF00856.28 OAJ25233.1 - 5.9e-06 26.8 0.2 0.0028 18.1 0.0 2.5 2 1 1 3 3 3 2 SET domain SAF PF08666.12 OAJ25233.1 - 0.12 13.1 0.0 4.3 8.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain HalOD2 PF18547.1 OAJ25234.1 - 0.78 9.7 3.4 1.9 8.4 3.4 1.6 1 0 0 1 1 1 0 Halobacterial output domain 2 NpwBP PF12622.7 OAJ25234.1 - 2.2 9.1 0.0 2.2 9.1 0.0 2.9 2 1 0 2 2 2 0 mRNA biogenesis factor FHA PF00498.26 OAJ25235.1 - 3.4e-05 24.1 0.0 6.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain DDE_Tnp_4 PF13359.6 OAJ25237.1 - 1.7e-06 27.8 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Solute_trans_a PF03619.16 OAJ25238.1 - 2.5e-79 266.5 12.7 3.1e-79 266.2 12.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ABC_tran PF00005.27 OAJ25239.1 - 5.7e-45 153.2 0.1 3.2e-22 79.5 0.0 4.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAJ25239.1 - 3e-20 73.3 0.1 0.0003 20.7 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ25239.1 - 6.7e-15 55.1 1.6 0.011 15.2 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ25239.1 - 3.6e-09 36.2 0.4 0.0031 17.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ25239.1 - 5e-06 27.1 7.0 0.014 15.9 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OAJ25239.1 - 6.5e-06 26.5 0.0 0.7 10.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAJ25239.1 - 2e-05 25.1 0.1 0.19 12.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ25239.1 - 3.3e-05 23.9 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ25239.1 - 5.1e-05 23.3 0.0 0.34 11.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 OAJ25239.1 - 8.4e-05 22.4 0.0 0.23 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Chromo PF00385.24 OAJ25239.1 - 0.00025 20.9 0.1 0.0007 19.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 OAJ25239.1 - 0.00026 20.9 0.0 1.1 9.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain G-alpha PF00503.20 OAJ25239.1 - 0.00036 19.8 0.0 0.41 9.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 OAJ25239.1 - 0.00046 20.4 3.3 0.038 14.1 0.2 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_30 PF13604.6 OAJ25239.1 - 0.00072 19.3 0.5 5.8 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAJ25239.1 - 0.00077 19.8 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase 4HB PF17947.1 OAJ25239.1 - 0.00085 19.3 0.0 0.0043 17.1 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain ATPase_2 PF01637.18 OAJ25239.1 - 0.0011 19.0 0.7 1.9 8.4 0.0 3.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OAJ25239.1 - 0.0012 19.1 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.6 OAJ25239.1 - 0.0012 19.3 1.9 8.6 7.0 0.0 4.8 5 0 0 5 5 4 0 HEAT-like repeat AAA_33 PF13671.6 OAJ25239.1 - 0.0012 19.0 0.1 2 8.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain CLASP_N PF12348.8 OAJ25239.1 - 0.0013 18.4 0.1 0.95 9.0 0.0 2.5 1 1 1 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 OAJ25239.1 - 0.0015 18.9 0.2 0.2 12.0 0.0 4.1 4 1 1 5 5 3 1 HEAT repeats AAA_16 PF13191.6 OAJ25239.1 - 0.0015 18.9 0.0 0.75 10.2 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 OAJ25239.1 - 0.0017 17.1 0.1 1.8 7.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 OAJ25239.1 - 0.0025 17.1 0.0 1.4 8.1 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 OAJ25239.1 - 0.003 16.6 0.2 0.38 9.7 0.0 2.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 OAJ25239.1 - 0.0038 17.4 0.1 0.57 10.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OAJ25239.1 - 0.0041 17.5 0.0 7.4 7.0 0.0 4.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAJ25239.1 - 0.0064 16.2 0.0 0.54 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 OAJ25239.1 - 0.0074 16.5 1.6 3.8 8.0 0.0 4.6 6 0 0 6 6 3 1 HEAT repeat Roc PF08477.13 OAJ25239.1 - 0.025 14.8 0.0 6.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 OAJ25239.1 - 0.041 13.5 0.0 2.5 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ25239.1 - 0.047 13.0 0.1 7.5 5.8 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 OAJ25239.1 - 0.047 13.5 0.3 4.9 6.9 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 OAJ25239.1 - 0.052 13.6 0.1 14 5.7 0.0 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OAJ25239.1 - 0.062 12.4 0.1 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAJ25239.1 - 0.071 13.1 2.1 11 6.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OAJ25239.1 - 0.081 13.0 0.0 17 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 OAJ25239.1 - 0.09 12.7 0.0 10 6.0 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 OAJ25239.1 - 0.12 11.9 0.2 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 OAJ25239.1 - 0.29 10.7 3.1 14 5.3 0.0 3.5 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 OAJ25240.1 - 3e-24 86.1 0.0 7.8e-23 81.5 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAJ25240.1 - 1.3e-08 35.1 0.1 0.0017 18.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ25240.1 - 9.3e-08 31.8 0.2 0.0034 16.9 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 OAJ25240.1 - 0.00012 21.9 0.1 0.0003 20.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 OAJ25240.1 - 0.00072 19.2 0.2 0.0014 18.3 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ25240.1 - 0.0099 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 OAJ25240.1 - 0.016 15.3 0.1 0.016 15.3 0.1 2.3 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 OAJ25240.1 - 0.021 15.4 0.5 0.072 13.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAJ25240.1 - 0.028 14.1 0.1 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAJ25240.1 - 0.031 14.5 0.1 0.24 11.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAJ25240.1 - 0.033 14.2 0.2 5.1 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OAJ25240.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 OAJ25240.1 - 0.066 13.7 0.0 0.066 13.7 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 OAJ25240.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ25240.1 - 0.099 13.0 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OAJ25240.1 - 0.13 12.6 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ25240.1 - 0.13 12.6 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 OAJ25240.1 - 0.14 12.6 0.1 3.1 8.2 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran_Xtn PF12848.7 OAJ25240.1 - 2.7 8.1 7.1 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 ABC transporter MAPEG PF01124.18 OAJ25241.1 - 1.6e-09 37.8 6.4 3.6e-09 36.6 6.4 1.8 1 1 0 1 1 1 1 MAPEG family Gram_pos_anchor PF00746.21 OAJ25241.1 - 4 7.5 8.6 7.9 6.5 0.6 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Proteasome PF00227.26 OAJ25246.1 - 9.2e-59 198.1 0.1 1.3e-58 197.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ25246.1 - 8.9e-15 54.1 0.8 3.1e-14 52.3 0.3 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 OAJ25246.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DsrH PF04077.12 OAJ25246.1 - 0.13 12.4 0.3 0.28 11.3 0.1 1.6 2 0 0 2 2 2 0 DsrH like protein zf-CCCH PF00642.24 OAJ25247.1 - 4e-13 48.9 15.3 1.4e-06 28.0 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ25247.1 - 0.00071 19.6 9.3 0.0018 18.2 1.9 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ25247.1 - 0.013 15.7 0.2 0.013 15.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 OAJ25247.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.4 2 1 0 2 2 2 0 Torus domain Spc24 PF08286.11 OAJ25248.1 - 4.8e-05 23.5 0.1 0.0049 17.1 0.0 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 ABC_membrane_2 PF06472.15 OAJ25248.1 - 0.023 14.1 0.6 0.037 13.4 0.6 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 KELK PF15796.5 OAJ25248.1 - 0.11 12.9 7.7 1.7 9.1 0.2 2.4 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CHGN PF05679.16 OAJ25248.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase LpxK PF02606.14 OAJ25248.1 - 0.19 10.8 0.9 0.29 10.2 0.9 1.3 1 1 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase FapA PF03961.13 OAJ25248.1 - 0.2 10.2 0.4 0.27 9.8 0.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med21 PF11221.8 OAJ25248.1 - 0.97 9.7 4.2 29 4.9 2.0 3.0 3 0 0 3 3 3 0 Subunit 21 of Mediator complex CBFD_NFYB_HMF PF00808.23 OAJ25249.1 - 3.3e-16 59.3 0.1 6.7e-16 58.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 OAJ25249.1 - 0.0038 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DEAD PF00270.29 OAJ25251.1 - 2.3e-26 92.7 0.0 7.3e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAJ25251.1 - 6.3e-19 68.5 1.2 2.2e-18 66.8 1.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAJ25251.1 - 1.7e-13 50.9 0.3 4.1e-12 46.4 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mito_carr PF00153.27 OAJ25251.1 - 5.3e-09 35.9 0.1 7.8e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein CDT1 PF08839.11 OAJ25251.1 - 4.4e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 OAJ25251.1 - 5.6e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_16 PF10294.9 OAJ25252.1 - 2.4e-15 56.7 0.0 1.4e-14 54.2 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase JAB PF01398.21 OAJ25253.1 - 3.8e-06 26.9 0.0 4.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NUMOD3 PF07460.11 OAJ25254.1 - 0.18 12.0 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Pet20 PF08692.10 OAJ25255.1 - 0.13 13.0 0.1 0.24 12.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Sigma54_activ_2 PF14532.6 OAJ25255.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Tnp_22_trimer PF17489.2 OAJ25255.1 - 3.5 7.7 7.2 3.1 7.8 5.0 2.0 2 0 0 2 2 2 0 L1 transposable element trimerization domain tRNA-synt_1c PF00749.21 OAJ25256.1 - 5.1e-69 232.6 0.0 9.1e-69 231.7 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ESSS PF10183.9 OAJ25257.1 - 2.8e-08 33.9 0.1 3.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Use1 PF09753.9 OAJ25258.1 - 0.036 13.8 1.9 0.056 13.2 1.9 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 TAF4 PF05236.14 OAJ25259.1 - 0.1 12.3 1.6 0.15 11.8 1.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IATP PF04568.12 OAJ25259.1 - 4 7.9 7.9 8.2 6.9 6.9 2.0 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DNA_pol_viral_C PF00336.18 OAJ25260.1 - 0.0047 16.3 0.1 0.0077 15.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Parvo_NS1 PF01057.17 OAJ25261.1 - 0.041 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2785 PF10978.8 OAJ25261.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) DUF4203 PF13886.6 OAJ25262.1 - 3.2e-44 151.0 23.6 3.2e-44 151.0 23.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) RVT_1 PF00078.27 OAJ25262.1 - 5.1e-14 52.3 0.0 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HCMV_UL124 PF17609.2 OAJ25262.1 - 0.016 15.4 7.8 0.14 12.4 7.8 2.8 1 0 0 1 1 1 0 Family of unknown function FAM220 PF15487.6 OAJ25263.1 - 0.024 14.3 2.1 0.033 13.8 2.1 1.2 1 0 0 1 1 1 0 FAM220 family RNA_pol_Rpb2_6 PF00562.28 OAJ25264.1 - 9.1e-109 364.1 0.0 2.6e-108 362.6 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ25264.1 - 8.2e-36 123.4 0.0 1.5e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAJ25264.1 - 1.9e-27 95.2 0.0 5.1e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 OAJ25264.1 - 6.6e-24 83.7 0.0 1.4e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 OAJ25264.1 - 1.4e-19 70.4 0.0 3.3e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ25264.1 - 1.5e-17 63.8 0.2 8.9e-15 54.9 0.1 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 ThuA PF06283.11 OAJ25267.1 - 1.6e-55 188.6 4.6 1.3e-45 156.2 0.1 3.0 3 0 0 3 3 3 2 Trehalose utilisation Pkinase PF00069.25 OAJ25268.1 - 7.3e-66 222.2 0.0 9e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25268.1 - 1.8e-28 99.5 0.1 2.9e-28 98.9 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ25268.1 - 3.3e-05 23.3 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ25268.1 - 3.7e-05 23.2 0.4 7.1e-05 22.3 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ25268.1 - 0.0026 16.8 0.1 0.0038 16.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ25268.1 - 0.01 15.8 0.7 1.2 8.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ25268.1 - 0.058 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family RNA_pol_L_2 PF13656.6 OAJ25269.1 - 4.1e-28 96.9 0.0 5.6e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ25269.1 - 1e-08 34.5 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.6 OAJ25269.1 - 0.12 10.4 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF1707 PF08044.11 OAJ25269.1 - 0.46 10.6 4.7 6.5 6.9 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1707) ox_reductase_C PF08635.10 OAJ25270.1 - 2.4e-77 257.4 0.1 3.8e-77 256.8 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OAJ25270.1 - 1.8e-21 77.2 0.0 5.7e-21 75.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAJ25270.1 - 0.017 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain ZZ PF00569.17 OAJ25277.1 - 1.8e-10 40.4 63.5 8.8e-06 25.4 2.1 6.7 6 1 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 OAJ25277.1 - 1.7e-05 24.7 0.1 3.8e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 OAJ25277.1 - 0.55 10.6 46.8 0.28 11.6 3.4 6.0 6 0 0 6 6 6 0 C1 domain Trp_DMAT PF11991.8 OAJ25278.1 - 1.7e-66 225.1 0.0 2.2e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Acetyltransf_17 PF17668.1 OAJ25278.1 - 0.019 15.8 0.0 0.091 13.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mei5_like PF17021.5 OAJ25278.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative double-strand recombination repair-like WD40 PF00400.32 OAJ25279.1 - 2.6e-44 148.3 22.0 3.2e-06 27.8 0.1 9.7 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 OAJ25279.1 - 3.2e-11 42.9 0.1 6.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ25279.1 - 8.7e-10 38.2 0.1 1.8e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAJ25279.1 - 1.8e-07 30.2 10.7 0.075 11.7 0.2 6.5 4 2 2 7 7 7 5 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAJ25279.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box ANAPC4_WD40 PF12894.7 OAJ25279.1 - 0.0036 17.6 0.2 23 5.4 0.0 4.8 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain E2_bind PF08825.10 OAJ25279.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain PALB2_WD40 PF16756.5 OAJ25279.1 - 0.33 9.8 5.6 6.7 5.5 0.3 4.0 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain RNA_lig_T4_1 PF09511.10 OAJ25280.1 - 1e-83 280.5 0.0 1.6e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 OAJ25280.1 - 1.3e-23 83.7 0.0 8e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 OAJ25280.1 - 1.6e-23 83.6 0.2 2.1e-14 53.9 0.0 2.4 1 1 1 2 2 2 2 tRNA ligase kinase domain KTI12 PF08433.10 OAJ25280.1 - 0.053 13.0 0.3 2.2 7.6 0.3 2.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF3381 PF11861.8 OAJ25280.1 - 4 7.2 9.7 9.3 6.0 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) MTHFR PF02219.17 OAJ25281.1 - 1.3e-110 369.3 0.0 1.7e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ThiF PF00899.21 OAJ25282.1 - 2.1e-24 86.2 0.0 5.7e-24 84.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family Pkinase PF00069.25 OAJ25284.1 - 3.6e-69 233.1 0.0 7.3e-69 232.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25284.1 - 1.2e-48 165.7 0.0 2e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ25284.1 - 0.00014 21.3 0.0 0.00097 18.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ25284.1 - 0.0078 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RTTN_N PF14726.6 OAJ25284.1 - 0.11 13.3 1.0 1.1 10.1 0.1 2.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning PYRIN PF02758.16 OAJ25284.1 - 0.17 12.1 0.1 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain 2-oxoacid_dh PF00198.23 OAJ25285.1 - 1.6e-77 260.1 0.1 2.1e-77 259.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ25285.1 - 3.9e-21 74.7 3.1 3.9e-21 74.7 3.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OAJ25285.1 - 9.9e-16 57.8 0.1 3e-15 56.2 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAJ25285.1 - 0.0094 15.8 1.3 4.5 7.2 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like Endostatin PF06482.11 OAJ25285.1 - 0.058 12.9 0.5 0.1 12.1 0.5 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DNA_alkylation PF08713.11 OAJ25285.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme YqfD PF06898.11 OAJ25285.1 - 0.42 9.4 1.3 0.73 8.6 1.3 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD RNA_pol_Rpc4 PF05132.14 OAJ25285.1 - 0.65 10.4 9.5 0.23 11.9 5.9 2.1 1 1 1 2 2 2 0 RNA polymerase III RPC4 SspB PF04386.13 OAJ25285.1 - 0.65 9.9 5.8 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Stringent starvation protein B Roughex PF06020.11 OAJ25285.1 - 5.3 6.0 7.3 8.5 5.4 7.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 OAJ25285.1 - 7.4 4.6 4.9 9.3 4.2 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.9 OAJ25285.1 - 7.5 6.1 29.7 4.5 6.8 16.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 OAJ25286.1 - 3.4 6.8 13.7 1.7 7.8 3.2 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter Nuf2 PF03800.14 OAJ25287.1 - 3.9e-33 114.5 0.0 1e-32 113.2 0.0 1.7 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 OAJ25287.1 - 1.4e-19 70.3 21.4 1.4e-19 70.3 21.4 4.0 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain EcKinase PF02958.20 OAJ25287.1 - 0.0084 15.5 3.0 0.016 14.6 2.4 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase DUF4083 PF13314.6 OAJ25287.1 - 0.21 11.6 0.9 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) VPS11_C PF12451.8 OAJ25287.1 - 0.97 9.7 5.5 12 6.2 0.3 3.5 3 0 0 3 3 2 0 Vacuolar protein sorting protein 11 C terminal DUF948 PF06103.11 OAJ25287.1 - 3.3 8.0 7.3 1 9.7 0.4 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OAJ25287.1 - 4.7 6.0 40.4 13 4.5 25.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 OAJ25287.1 - 5.9 7.0 21.0 0.35 10.9 5.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 OAJ25287.1 - 6.3 5.8 31.8 2.2 7.3 16.8 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 OAJ25287.1 - 6.4 6.8 37.2 0.37 10.9 2.9 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 OAJ25287.1 - 7.5 5.8 41.0 1.6 8.1 15.3 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding SIR2 PF02146.17 OAJ25288.1 - 3.9e-52 176.7 0.0 2.4e-51 174.2 0.0 2.2 2 1 0 2 2 2 1 Sir2 family DUF592 PF04574.13 OAJ25288.1 - 2.2e-08 34.0 0.3 2.9e-07 30.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 OAJ25288.1 - 0.18 11.5 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain WD40 PF00400.32 OAJ25289.1 - 2.6e-12 47.1 9.1 7.5e-06 26.6 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ25289.1 - 2.6e-05 24.4 0.0 0.00038 20.7 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Arf PF00025.21 OAJ25290.1 - 1.5e-64 216.6 0.0 1.7e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ25290.1 - 4.7e-09 35.9 0.0 1.7e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAJ25290.1 - 8.2e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OAJ25290.1 - 6.2e-08 32.4 0.0 7.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAJ25290.1 - 7.9e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ25290.1 - 8.5e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OAJ25290.1 - 2.8e-05 23.6 0.0 3.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ25290.1 - 0.04 13.5 0.1 0.86 9.1 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CENP-M PF11111.8 OAJ25290.1 - 0.042 13.0 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 OAJ25290.1 - 0.045 13.3 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAJ25290.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L26 PF16906.5 OAJ25291.1 - 5.9e-39 132.4 2.2 7.2e-39 132.1 2.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAJ25291.1 - 1.5e-08 34.3 1.9 3.2e-08 33.3 1.9 1.6 1 0 0 1 1 1 1 KOW motif dsDNA_bind PF01984.20 OAJ25292.1 - 1.3e-31 109.1 6.9 4e-31 107.6 6.9 1.7 1 1 0 1 1 1 1 Double-stranded DNA-binding domain PIG-S PF10510.9 OAJ25293.1 - 3.9e-109 365.8 0.1 5.4e-109 365.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myosin_head PF00063.21 OAJ25294.1 - 1.1e-260 866.6 0.6 1.8e-260 865.9 0.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 OAJ25294.1 - 1.8e-27 95.7 1.0 1.8e-27 95.7 1.0 3.4 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 OAJ25294.1 - 9.6e-06 25.0 33.8 0.6 10.1 0.4 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif CALCOCO1 PF07888.11 OAJ25294.1 - 0.0011 18.0 21.9 0.002 17.1 21.9 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.10 OAJ25294.1 - 0.0012 19.0 5.5 0.0012 19.0 5.5 3.1 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family FlxA PF14282.6 OAJ25294.1 - 0.005 16.8 10.5 0.2 11.6 1.2 3.0 2 0 0 2 2 2 2 FlxA-like protein AAA_22 PF13401.6 OAJ25294.1 - 0.0052 17.1 0.4 0.024 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain DivIC PF04977.15 OAJ25294.1 - 0.0057 16.4 6.3 0.0057 16.4 6.3 3.1 2 1 1 3 3 3 1 Septum formation initiator Med9 PF07544.13 OAJ25294.1 - 0.02 15.0 13.9 0.035 14.2 3.2 3.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 OAJ25294.1 - 0.22 10.1 16.2 0.38 9.4 15.7 1.6 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ25294.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.4 3 1 0 3 3 2 0 AAA ATPase domain Phage_GPO PF05929.11 OAJ25294.1 - 1 8.9 11.5 2.5 7.7 11.5 1.7 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_GP20 PF06810.11 OAJ25294.1 - 1.3 8.8 17.8 1 9.1 5.7 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 OAJ25294.1 - 1.4 9.1 29.0 1.1e+02 2.9 29.0 2.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 OAJ25294.1 - 1.9 7.3 29.4 56 2.4 29.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 OAJ25294.1 - 1.9 8.5 15.7 0.84 9.7 1.7 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OAJ25294.1 - 2 8.5 31.7 0.76 9.8 11.3 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ABC_tran PF00005.27 OAJ25294.1 - 2.6 8.6 5.2 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter TolA_bind_tri PF16331.5 OAJ25294.1 - 4.4 7.4 18.8 0.023 14.8 2.6 3.6 3 0 0 3 3 3 0 TolA binding protein trimerisation His_kinase PF06580.13 OAJ25294.1 - 4.6 7.6 5.8 6 7.3 0.0 3.8 4 0 0 4 4 4 0 Histidine kinase Dynactin PF12455.8 OAJ25296.1 - 2.1e-52 178.1 1.4 2.1e-52 178.1 1.4 4.4 3 2 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 OAJ25296.1 - 9.1e-21 73.7 1.1 1.8e-20 72.7 1.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain TraI PF07057.11 OAJ25296.1 - 0.47 10.6 4.9 2.4 8.3 4.9 2.3 1 0 0 1 1 1 0 DNA helicase TraI RNA_pol_Rpb1_5 PF04998.17 OAJ25299.1 - 1.6e-88 296.6 0.0 3.2e-88 295.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAJ25299.1 - 1.4e-63 214.0 0.0 2.6e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ25299.1 - 5.4e-34 117.4 0.0 1.1e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAJ25299.1 - 1.7e-29 103.2 0.3 3e-23 82.6 0.0 4.2 5 0 0 5 5 5 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAJ25299.1 - 8.1e-22 77.2 0.0 2.8e-21 75.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Il13Ra_Ig PF18001.1 OAJ25299.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain DUF913 PF06025.12 OAJ25299.1 - 6 5.7 7.5 15 4.5 4.7 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) adh_short_C2 PF13561.6 OAJ25300.1 - 2.6e-53 181.0 0.0 3.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ25300.1 - 1.9e-43 148.2 0.1 2.3e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ25300.1 - 4.9e-12 46.1 0.0 6.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF2235 PF09994.9 OAJ25302.1 - 8.1e-73 245.3 0.0 1.1e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 OAJ25303.1 - 1.2e-73 248.0 0.0 1.8e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DoxX_2 PF13564.6 OAJ25303.1 - 0.0068 16.5 0.2 19 5.4 0.0 3.3 3 0 0 3 3 3 2 DoxX-like family Gln-synt_C PF00120.24 OAJ25304.1 - 6.5e-15 55.0 0.0 6.8e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAJ25304.1 - 6.5e-13 48.2 0.0 1.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.24 OAJ25304.1 - 0.074 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PAPS_reduct PF01507.19 OAJ25305.1 - 3.7e-20 72.7 0.0 6.4e-15 55.6 0.0 2.6 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF2235 PF09994.9 OAJ25306.1 - 2.2e-71 240.6 0.0 2.9e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 OAJ25307.1 - 2.1e-64 217.7 0.0 3.4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SH3_9 PF14604.6 OAJ25309.1 - 1.1e-14 54.0 0.3 1.4e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ25309.1 - 7.5e-13 47.9 0.1 9.5e-13 47.5 0.1 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ25309.1 - 1.6e-07 30.9 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain LRR_8 PF13855.6 OAJ25310.1 - 7.5e-11 41.6 2.4 1.4e-10 40.7 2.4 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OAJ25310.1 - 2.7e-08 34.0 2.7 1.7e-06 28.2 0.2 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ25310.1 - 0.00085 19.5 2.2 8.6 7.3 0.2 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat DUF1772 PF08592.11 OAJ25311.1 - 2.6e-16 60.2 1.5 2.9e-16 60.0 1.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Cation_efflux PF01545.21 OAJ25312.1 - 4.7e-26 91.8 9.7 6.2e-26 91.4 9.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ25312.1 - 6.1e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pkinase PF00069.25 OAJ25314.1 - 1.5e-28 99.9 0.0 6.1e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25314.1 - 1.9e-13 50.3 0.0 1.2e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ25314.1 - 0.029 13.7 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Urm1 PF09138.11 OAJ25315.1 - 3.9e-32 110.5 0.0 5.9e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) His_Phos_1 PF00300.22 OAJ25315.1 - 5.9e-30 104.4 1.7 5.3e-28 98.0 1.7 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThiS PF02597.20 OAJ25315.1 - 0.022 15.4 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 ThiS family DAGAT PF03982.13 OAJ25316.1 - 2.7e-94 315.4 0.0 1.6e-49 168.5 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Glyco_trans_2_3 PF13632.6 OAJ25316.1 - 0.083 12.8 1.0 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Glycosyl transferase family group 2 DUF2235 PF09994.9 OAJ25317.1 - 2.2e-65 220.9 0.0 3.6e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tim17 PF02466.19 OAJ25318.1 - 7.2e-19 68.2 8.2 1.1e-18 67.6 8.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pex14_N PF04695.13 OAJ25318.1 - 1.3 9.7 11.0 2.2 8.9 11.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK2AP PF09806.9 OAJ25318.1 - 1.4 8.9 6.2 2.1 8.4 6.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2235 PF09994.9 OAJ25319.1 - 1.2e-66 225.0 0.0 1.6e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Mgm101p PF06420.12 OAJ25320.1 - 1.4e-82 275.3 0.0 1.8e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 RRM_1 PF00076.22 OAJ25321.1 - 1.5e-12 47.1 0.0 2.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAF1_ABF1 PF04684.13 OAJ25321.1 - 4.1 6.4 6.1 5.7 5.9 6.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RasGAP PF00616.19 OAJ25325.1 - 1.8e-47 161.8 2.3 1.7e-46 158.5 0.0 3.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAJ25325.1 - 1.3e-46 158.2 4.3 5.6e-46 156.1 4.3 2.3 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 OAJ25325.1 - 6e-23 78.4 28.0 0.024 14.4 0.0 10.0 9 0 0 9 9 9 8 IQ calmodulin-binding motif CH PF00307.31 OAJ25325.1 - 3.8e-16 59.2 0.0 8.5e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain ATPase_2 PF01637.18 OAJ25326.1 - 6.2e-07 29.6 0.1 1.5e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OAJ25326.1 - 0.00026 21.4 1.9 0.0026 18.2 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ25326.1 - 0.015 15.6 0.0 0.055 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ25326.1 - 0.32 10.8 1.6 0.82 9.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain UDG PF03167.19 OAJ25327.1 - 2.4e-16 60.1 0.0 9.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily FAM199X PF15814.5 OAJ25327.1 - 2.5 7.1 12.9 0.034 13.2 5.0 1.8 2 0 0 2 2 2 0 Protein family FAM199X adh_short PF00106.25 OAJ25328.1 - 4.6e-20 71.9 0.0 8.7e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ25328.1 - 1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF282 PF03380.14 OAJ25328.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 KR PF08659.10 OAJ25328.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 KR domain Polysacc_deac_1 PF01522.21 OAJ25329.1 - 1.7e-13 50.5 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase Retrotran_gag_2 PF14223.6 OAJ25330.1 - 6.3e-24 84.2 0.3 8.2e-24 83.8 0.3 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RBFA PF02033.18 OAJ25330.1 - 0.026 15.0 0.1 0.06 13.8 0.1 1.6 1 1 0 1 1 1 0 Ribosome-binding factor A Zn_clus PF00172.18 OAJ25333.1 - 2.3e-06 27.6 6.8 4.1e-06 26.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 OAJ25333.1 - 0.12 12.5 0.9 0.24 11.6 0.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Xan_ur_permease PF00860.20 OAJ25334.1 - 3.3e-26 91.9 28.5 1.1e-24 86.9 28.5 2.2 1 1 0 1 1 1 1 Permease family F-box-like PF12937.7 OAJ25336.1 - 0.17 11.8 2.9 0.23 11.4 0.4 2.5 3 0 0 3 3 3 0 F-box-like Ribosomal_L5e PF17144.4 OAJ25338.1 - 3e-76 255.0 0.0 3e-76 255.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAJ25338.1 - 1.3e-33 115.8 5.2 1.3e-33 115.8 5.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 OAJ25338.1 - 0.035 14.5 0.2 0.035 14.5 0.2 1.8 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast MtrA PF04208.14 OAJ25338.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A PI-PLC-X PF00388.19 OAJ25340.1 - 4.4e-50 169.0 0.0 7.6e-50 168.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAJ25340.1 - 3.9e-38 130.3 0.1 1e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 OAJ25340.1 - 0.016 15.7 2.8 0.24 11.9 0.1 3.2 2 2 1 3 3 3 0 Pleckstrin homology domain ZFYVE21_C PF16696.5 OAJ25340.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus GDPD PF03009.17 OAJ25340.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF4744 PF15918.5 OAJ25341.1 - 0.031 15.1 0.1 0.12 13.2 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) DUF3040 PF11239.8 OAJ25342.1 - 0.5 10.7 3.4 0.94 9.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4307 PF14155.6 OAJ25342.1 - 4.5 7.1 6.7 12 5.8 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Ribosomal_L15e PF00827.17 OAJ25345.1 - 2.4e-87 291.6 7.4 2.7e-87 291.4 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF5310 PF17237.2 OAJ25346.1 - 3.2e-17 62.1 5.2 3.9e-17 61.8 5.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) PK PF00224.21 OAJ25347.1 - 6.3e-160 531.8 1.1 7.7e-160 531.5 1.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAJ25347.1 - 2.8e-37 127.5 0.0 6.7e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAJ25347.1 - 0.00028 20.1 0.9 0.001 18.3 0.9 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAJ25347.1 - 0.0045 16.0 0.3 0.051 12.6 0.0 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 OAJ25347.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 OAJ25354.1 - 5.5e-08 32.5 0.0 7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ25354.1 - 0.00021 20.9 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ25354.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Dickkopf_N PF04706.12 OAJ25355.1 - 0.12 12.9 0.4 0.12 12.9 0.4 9.8 7 4 3 10 10 10 0 Dickkopf N-terminal cysteine-rich region Utp14 PF04615.13 OAJ25355.1 - 5 5.6 20.1 6.3 5.2 20.1 1.0 1 0 0 1 1 1 0 Utp14 protein Chs7 PF12271.8 OAJ25356.1 - 1.2e-115 385.8 17.8 1.4e-115 385.6 17.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Methyltransf_16 PF10294.9 OAJ25357.1 - 3.3e-40 137.6 0.0 4.8e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAJ25357.1 - 0.0024 17.4 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAJ25357.1 - 0.038 14.7 0.1 0.078 13.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ25357.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Dioxygenase_C PF00775.21 OAJ25358.1 - 7.9e-05 22.2 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase MG4 PF17789.1 OAJ25358.1 - 0.073 13.2 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 Macroglobulin domain MG4 HIT PF01230.23 OAJ25359.1 - 5.7e-16 59.1 0.0 1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ25359.1 - 6.3e-08 33.1 0.0 1.8e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAJ25359.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 SOG2 PF10428.9 OAJ25360.1 - 0.14 11.3 24.2 0.2 10.8 24.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dickkopf_N PF04706.12 OAJ25360.1 - 0.17 12.4 0.2 0.17 12.4 0.2 10.0 6 4 2 9 9 9 0 Dickkopf N-terminal cysteine-rich region PHD PF00628.29 OAJ25361.1 - 0.0033 17.3 10.6 0.0072 16.2 10.6 1.5 1 0 0 1 1 1 1 PHD-finger Aldo_ket_red PF00248.21 OAJ25362.1 - 1.2e-69 234.8 0.0 1.4e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UVR PF02151.19 OAJ25362.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif rve PF00665.26 OAJ25364.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 OAJ25364.1 - 0.028 14.2 0.1 0.084 12.7 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Meleagrin PF08189.11 OAJ25365.1 - 0.36 10.6 3.2 9.4 6.0 0.3 2.7 2 1 0 2 2 2 0 Meleagrin/Cygnin family DUF659 PF04937.15 OAJ25367.1 - 7.8e-14 51.8 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 OAJ25367.1 - 0.00019 21.2 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PTPA PF03095.15 OAJ25369.1 - 3.2e-96 322.3 0.0 4e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SecY PF00344.20 OAJ25370.1 - 9.9e-75 251.6 7.3 1.2e-74 251.3 7.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAJ25370.1 - 8.9e-17 60.6 0.3 2.5e-16 59.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Proton_antipo_N PF00662.20 OAJ25370.1 - 0.087 12.9 0.4 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Claudin_3 PF06653.11 OAJ25370.1 - 0.97 9.4 5.2 1.5 8.7 0.0 3.3 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Glyco_hydro_79C PF16862.5 OAJ25371.1 - 6.5e-14 52.7 0.2 1.4e-13 51.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain BH3 PF15285.6 OAJ25371.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting AhpC-TSA PF00578.21 OAJ25374.1 - 3.3e-20 72.2 0.0 5.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ25374.1 - 1.3e-12 47.6 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin FIST PF08495.10 OAJ25375.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FIST N domain Abhydrolase_1 PF00561.20 OAJ25376.1 - 2.2e-20 73.4 0.0 2.1e-19 70.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ25376.1 - 1.8e-14 54.9 1.9 1.8e-14 54.9 1.9 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ25376.1 - 8.3e-09 35.1 0.0 2.9e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 OAJ25376.1 - 1.3e-06 28.4 2.1 1.1e-05 25.4 0.0 3.0 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Esterase PF00756.20 OAJ25376.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 OAJ25376.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Zn_clus PF00172.18 OAJ25377.1 - 1.6e-07 31.3 9.6 2.9e-07 30.5 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.33 OAJ25378.1 - 1.6e-09 37.4 1.0 3.7e-09 36.2 1.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ25378.1 - 0.0013 18.5 0.2 0.0033 17.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 OAJ25378.1 - 0.015 15.3 0.1 0.03 14.3 0.0 1.6 2 0 0 2 2 2 0 F-box-like domain F-box_4 PF15966.5 OAJ25378.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 F-box DUF1771 PF08590.10 OAJ25379.1 - 2.8e-18 66.0 4.0 4.1e-18 65.5 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAJ25379.1 - 7.5e-13 48.7 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF3450 PF11932.8 OAJ25380.1 - 0.0054 16.1 0.3 0.23 10.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) DUF4140 PF13600.6 OAJ25380.1 - 0.0099 16.3 1.3 0.49 10.9 1.3 2.1 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 OAJ25380.1 - 0.011 16.2 0.2 1.7 9.1 0.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Hamartin PF04388.12 OAJ25385.1 - 0.0037 16.0 0.0 0.0037 16.0 0.0 3.6 3 1 0 3 3 3 2 Hamartin protein Aminotran_4 PF01063.19 OAJ25385.1 - 0.005 16.7 0.0 0.052 13.4 0.0 2.6 1 1 0 1 1 1 1 Amino-transferase class IV DUF1843 PF08898.10 OAJ25385.1 - 1.1 9.8 7.4 3.2 8.3 0.2 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Phlebovirus_NSM PF07246.11 OAJ25385.1 - 2.2 7.6 6.7 1.1 8.5 3.6 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M tRNA-synt_1c PF00749.21 OAJ25386.1 - 7.3e-106 353.6 0.4 1.1e-105 353.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 OAJ25386.1 - 2.3e-36 125.3 0.0 4.8e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 OAJ25386.1 - 3e-29 102.1 0.1 1e-28 100.4 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 OAJ25386.1 - 9e-08 32.9 6.2 9e-08 32.9 6.2 2.5 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_S5 PF00333.20 OAJ25387.1 - 1.5e-29 101.7 0.5 3.7e-29 100.5 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAJ25387.1 - 4.5e-23 80.5 0.1 7.5e-23 79.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OAJ25387.1 - 3.9 8.1 8.4 8.4 7.0 8.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-ANAPC11 PF12861.7 OAJ25388.1 - 6e-31 106.4 9.1 7.7e-31 106.0 9.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAJ25388.1 - 2.7e-19 69.2 14.0 3.9e-19 68.7 14.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ25388.1 - 1.1e-06 28.9 14.5 1.1e-05 25.6 14.5 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ25388.1 - 2.1e-05 24.3 11.5 7.9e-05 22.5 11.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ25388.1 - 0.011 15.6 17.7 0.16 11.8 17.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ25388.1 - 0.78 9.5 13.8 14 5.5 13.8 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-HC5HC2H_2 PF13832.6 OAJ25388.1 - 1.1 9.5 10.4 0.28 11.3 7.6 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain TAFII28 PF04719.14 OAJ25389.1 - 6e-29 100.0 0.0 8.2e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF4770 PF15994.5 OAJ25389.1 - 0.08 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Peptidase_M14 PF00246.24 OAJ25390.1 - 6.8e-08 32.7 0.0 4.7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OAJ25390.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide UPF0184 PF03670.13 OAJ25390.1 - 0.15 12.5 0.1 0.29 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Sel1 PF08238.12 OAJ25391.1 - 2.1e-15 56.8 19.4 0.013 16.1 0.2 8.4 8 0 0 8 8 8 6 Sel1 repeat TPR_1 PF00515.28 OAJ25391.1 - 0.0087 15.8 3.6 0.26 11.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ25391.1 - 0.098 12.8 0.0 0.098 12.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ25391.1 - 0.2 12.0 0.0 0.2 12.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ25391.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.18 OAJ25392.1 - 4.5e-38 129.5 1.6 7.2e-38 128.8 1.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAJ25392.1 - 0.00018 21.3 0.7 0.00041 20.2 0.7 1.6 1 0 0 1 1 1 1 KOW motif Ribosom_S12_S23 PF00164.25 OAJ25393.1 - 7.8e-48 160.8 0.6 9.9e-48 160.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Arrestin_C PF02752.22 OAJ25394.1 - 9.1e-15 55.3 0.0 4.2e-13 49.9 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ25394.1 - 1.5e-06 28.3 0.0 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain SKIP_SNW PF02731.15 OAJ25395.1 - 3.4e-70 234.8 1.3 3.4e-70 234.8 1.3 1.9 2 0 0 2 2 2 1 SKIP/SNW domain FAD_binding_2 PF00890.24 OAJ25396.1 - 8.9e-87 291.9 0.1 1e-86 291.7 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ25396.1 - 3.7e-08 33.5 0.5 1.7e-07 31.4 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ25396.1 - 5e-07 29.6 2.9 3e-06 27.1 2.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ25396.1 - 9.8e-07 28.3 0.1 7.4e-05 22.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ25396.1 - 1.8e-06 27.4 0.1 5.2e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ25396.1 - 5.1e-06 27.0 0.9 0.00022 21.7 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ25396.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ25396.1 - 0.00012 20.9 0.1 0.00012 20.9 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ25396.1 - 0.00062 19.1 0.0 0.00062 19.1 0.0 1.9 3 0 0 3 3 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAJ25396.1 - 0.0015 17.7 0.6 0.0015 17.7 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAJ25396.1 - 0.0045 16.1 0.6 0.0081 15.2 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAJ25396.1 - 0.022 14.0 2.1 0.034 13.4 0.2 2.1 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.6 OAJ25396.1 - 0.024 13.9 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAJ25396.1 - 0.027 14.9 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAJ25396.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ25396.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 OAJ25396.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ribosomal_S5 PF00333.20 OAJ25397.1 - 2.3e-17 62.7 3.0 3e-17 62.3 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAJ25397.1 - 3e-17 61.8 0.0 7.2e-17 60.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRP1_N PF06424.12 OAJ25397.1 - 0.13 12.7 5.0 5.3 7.4 0.8 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Pex14_N PF04695.13 OAJ25397.1 - 0.4 11.3 6.5 0.77 10.4 6.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.9 OAJ25397.1 - 0.84 8.4 6.3 1 8.1 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 OAJ25397.1 - 1.3 8.9 8.2 1.7 8.5 8.2 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 OAJ25397.1 - 5.2 7.0 15.1 9.5 6.2 15.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Rsa3 PF14615.6 OAJ25398.1 - 8.6e-07 28.4 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TPR_1 PF00515.28 OAJ25400.1 - 5.9e-19 67.0 0.1 4.8e-05 23.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ25400.1 - 1.4e-14 53.0 1.3 0.00075 19.4 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ25400.1 - 1.5e-13 50.2 0.4 0.036 13.8 0.0 4.9 4 1 1 5 5 5 4 TPR repeat TPR_14 PF13428.6 OAJ25400.1 - 2.4e-12 46.6 3.4 0.035 14.9 0.0 6.6 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ25400.1 - 8.5e-12 44.3 0.2 0.0034 17.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ25400.1 - 1.9e-09 36.9 0.0 0.052 13.6 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ25400.1 - 4.3e-09 36.1 4.6 0.028 14.8 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ25400.1 - 4.1e-07 30.4 2.7 0.11 13.0 0.0 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ25400.1 - 1e-06 28.9 0.9 0.0022 18.3 0.0 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ25400.1 - 0.00014 21.9 7.3 0.74 10.0 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ25400.1 - 0.01 16.5 22.3 0.16 12.6 0.0 6.3 5 2 3 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ25400.1 - 0.014 15.2 2.9 0.14 12.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ25400.1 - 0.21 11.9 10.8 0.17 12.2 0.4 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 OAJ25401.1 - 1.4e-13 51.5 0.0 1.8e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.27 OAJ25402.1 - 1.6e-18 67.1 0.0 2.5e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIF4E-T PF10477.9 OAJ25402.1 - 0.042 12.7 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E F-box PF00646.33 OAJ25403.1 - 3.3e-08 33.2 0.0 7.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ25403.1 - 0.00052 19.8 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ25403.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box CENP-B_dimeris PF09026.10 OAJ25403.1 - 0.045 14.1 3.3 0.093 13.1 3.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OAJ25403.1 - 1.2 8.9 5.2 1.8 8.2 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 OAJ25404.1 - 9e-55 185.9 0.0 5.5e-52 176.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25404.1 - 1.7e-25 89.8 0.0 1.8e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ25404.1 - 1.1e-07 31.5 0.0 2.6e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ25404.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ25404.1 - 0.045 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 F-box PF00646.33 OAJ25406.1 - 0.001 18.9 0.1 0.0028 17.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ25406.1 - 0.015 15.2 0.4 0.031 14.1 0.4 1.6 1 0 0 1 1 1 0 F-box-like EF-hand_6 PF13405.6 OAJ25409.1 - 6.3e-10 38.2 2.1 8.3e-05 22.2 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ25409.1 - 5.1e-08 31.9 5.7 0.00047 19.5 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OAJ25409.1 - 2.1e-07 31.3 5.1 2.7e-06 27.7 1.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ25409.1 - 0.0044 16.5 2.5 0.09 12.3 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OAJ25409.1 - 0.13 12.2 2.7 7.7 6.5 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain pair PRTP PF01366.18 OAJ25409.1 - 0.16 9.9 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Nucleos_tra2_C PF07662.13 OAJ25410.1 - 2.1e-69 233.5 0.5 4.4e-69 232.5 0.5 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAJ25410.1 - 2.5e-16 60.0 6.9 2.5e-16 60.0 6.9 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OAJ25410.1 - 1.2 9.4 14.2 4.1 7.7 7.6 3.4 2 1 0 2 2 2 0 Nucleoside recognition DHHC PF01529.20 OAJ25411.1 - 1.1e-30 106.5 0.0 3.7e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase ATE_C PF04377.15 OAJ25412.1 - 1e-46 158.9 0.1 1.6e-46 158.3 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OAJ25412.1 - 1.7e-25 89.2 0.2 3.5e-25 88.2 0.2 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Hydrolase_4 PF12146.8 OAJ25413.1 - 2.2e-44 151.5 0.0 3.9e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_transf_8 PF01501.20 OAJ25413.1 - 6e-11 42.4 0.0 1.9e-10 40.7 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.7 OAJ25413.1 - 2.1e-10 41.6 0.6 6.2e-10 40.0 0.0 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ25413.1 - 4.5e-09 36.3 1.0 3.5e-07 30.1 1.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ25413.1 - 0.00076 19.0 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 OAJ25413.1 - 0.0046 16.6 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Mannosyl_trans3 PF11051.8 OAJ25413.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative DUF915 PF06028.11 OAJ25413.1 - 0.031 13.6 0.0 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 OAJ25413.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase tRNA-synt_2 PF00152.20 OAJ25414.1 - 2.5e-85 286.4 0.0 2.5e-85 286.4 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ25414.1 - 5.5e-11 42.3 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF677 PF05055.12 OAJ25414.1 - 0.068 12.1 0.8 0.099 11.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) tRNA_anti_2 PF13742.6 OAJ25414.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2 PF00152.20 OAJ25415.1 - 7.5e-35 120.5 0.1 7.5e-35 120.5 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ25415.1 - 1.4e-05 25.0 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATP11 PF06644.11 OAJ25416.1 - 2.2e-70 237.5 0.1 2.2e-70 237.5 0.1 1.5 2 0 0 2 2 2 1 ATP11 protein PepSY_2 PF13670.6 OAJ25416.1 - 3 7.9 6.0 0.68 10.0 1.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain PUF PF00806.19 OAJ25428.1 - 5.9e-58 189.4 2.2 4.9e-10 38.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Acyl-CoA_dh_N PF02771.16 OAJ25428.1 - 0.034 14.8 0.0 14 6.3 0.0 3.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Spt20 PF12090.8 OAJ25428.1 - 0.52 9.9 5.8 1.1 8.8 5.8 1.5 1 0 0 1 1 1 0 Spt20 family Fer2_3 PF13085.6 OAJ25429.1 - 2.3e-32 111.2 0.0 3.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAJ25429.1 - 5.2e-09 36.5 6.1 5.2e-09 36.5 6.1 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ25429.1 - 2.9e-07 30.8 6.6 2.9e-07 30.8 6.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAJ25429.1 - 8.6e-07 29.0 3.6 8.6e-07 29.0 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAJ25429.1 - 0.013 15.4 1.4 0.013 15.4 1.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 OAJ25429.1 - 0.018 15.7 6.4 0.018 15.7 6.4 2.6 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OAJ25429.1 - 0.37 11.0 0.1 0.37 11.0 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAJ25429.1 - 2.7 8.2 14.8 0.52 10.5 8.6 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Glyco_hydro_45 PF02015.16 OAJ25430.1 - 6.5e-52 176.5 6.3 7.5e-52 176.3 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.16 OAJ25431.1 - 2.5e-28 99.5 4.3 3.2e-28 99.1 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 RRM_1 PF00076.22 OAJ25432.1 - 2e-10 40.4 0.0 5.6e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 OAJ25432.1 - 0.0044 17.6 3.8 0.011 16.3 3.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) Rpn3_C PF08375.11 OAJ25432.1 - 0.47 10.9 3.4 6.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Tetraspanin PF00335.20 OAJ25433.1 - 5.2e-14 52.5 6.5 6.9e-14 52.1 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family YL1_C PF08265.11 OAJ25434.1 - 2.3e-13 49.6 0.6 4.4e-13 48.7 0.6 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MOFRL PF05161.13 OAJ25434.1 - 0.12 12.6 2.4 0.19 11.9 2.4 1.4 1 0 0 1 1 1 0 MOFRL family tRNA-synt_2 PF00152.20 OAJ25435.1 - 2.7e-66 223.8 0.0 9.7e-66 222.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ25435.1 - 8.2e-05 22.5 0.0 0.00036 20.5 0.0 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2428 PF10350.9 OAJ25436.1 - 7e-48 163.3 0.3 7e-48 163.3 0.3 2.1 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 OAJ25436.1 - 0.0016 18.5 2.1 31 5.2 0.0 4.4 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 OAJ25436.1 - 0.0042 17.4 0.9 0.047 14.1 0.4 3.2 2 1 0 2 2 2 1 HEAT repeats Nairo_nucleo PF02477.15 OAJ25436.1 - 0.081 11.7 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Nucleocapsid N protein SRP14 PF02290.15 OAJ25437.1 - 3.7e-13 49.6 0.1 1.9e-12 47.4 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle 14kD protein EF-hand_5 PF13202.6 OAJ25437.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 EF hand GoLoco PF02188.17 OAJ25438.1 - 0.49 10.0 3.9 6 6.5 0.4 3.2 3 0 0 3 3 3 0 GoLoco motif HECT_2 PF09814.9 OAJ25439.1 - 9.4e-18 64.2 0.0 1e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Bromo_TP PF07524.13 OAJ25440.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated YTH PF04146.15 OAJ25441.1 - 5.4e-34 117.5 0.3 1.4e-33 116.2 0.0 1.9 2 0 0 2 2 2 1 YT521-B-like domain Mem_trans PF03547.18 OAJ25442.1 - 8.7e-37 126.4 6.0 1.1e-33 116.2 0.1 2.7 2 1 0 2 2 2 2 Membrane transport protein dCMP_cyt_deam_1 PF00383.23 OAJ25443.1 - 1.4e-13 50.6 0.4 2.4e-13 49.8 0.4 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OAJ25443.1 - 6.5e-11 42.6 4.6 5.4e-10 39.6 0.6 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAJ25443.1 - 0.00028 20.6 1.9 0.025 14.2 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Thiolase_N PF00108.23 OAJ25444.1 - 6.1e-65 219.2 0.1 1.4e-64 218.0 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ25444.1 - 1.8e-44 150.3 0.3 4.3e-44 149.1 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ25444.1 - 2.9e-06 27.0 0.1 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain LIP PF03583.14 OAJ25445.1 - 4.2e-51 174.0 0.1 5.9e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 OAJ25445.1 - 0.11 11.7 0.1 1.1 8.5 0.1 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAJ25446.1 - 4.8e-59 199.8 0.0 6.2e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OAJ25446.1 - 8.5e-08 31.8 0.1 0.0011 18.2 0.1 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ25446.1 - 3.9e-07 30.9 0.1 4.4e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ25446.1 - 7e-06 25.9 0.0 2.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 OAJ25446.1 - 0.026 14.0 0.0 0.064 12.7 0.0 1.9 1 1 1 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 OAJ25446.1 - 0.046 13.4 0.0 0.24 11.0 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Cutinase PF01083.22 OAJ25446.1 - 0.05 13.6 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 OAJ25446.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CK_II_beta PF01214.18 OAJ25447.1 - 2.6e-80 268.5 0.0 3.2e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DOCK_N PF16172.5 OAJ25449.1 - 8.6e-115 383.7 0.0 2.4e-114 382.2 0.0 1.8 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 OAJ25449.1 - 6.6e-68 229.6 1.5 7.9e-68 229.4 0.0 1.9 3 0 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 OAJ25449.1 - 9.4e-52 175.7 0.0 2.9e-51 174.1 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins ELFV_dehydrog PF00208.21 OAJ25451.1 - 7.1e-44 150.4 0.8 8.8e-44 150.0 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OAJ25451.1 - 5.1e-08 32.9 0.0 1.4e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_L35Ae PF01247.18 OAJ25451.1 - 0.042 14.0 0.6 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L35Ae SBDS_C PF09377.10 OAJ25460.1 - 3.7e-36 123.7 0.5 5.9e-36 123.0 0.5 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 OAJ25460.1 - 3.1e-33 113.7 0.6 5.4e-33 112.9 0.2 1.6 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.19 OAJ25460.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Nop52 PF05997.12 OAJ25461.1 - 6.4e-60 202.6 0.0 9.2e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Peptidase_C8 PF03569.13 OAJ25461.1 - 0.15 11.6 0.2 0.27 10.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase family C8 DNA_pol_phi PF04931.13 OAJ25461.1 - 0.49 8.4 5.9 0.76 7.8 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 OAJ25461.1 - 6.1 5.3 20.5 0.22 10.0 13.2 1.9 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HMG_box PF00505.19 OAJ25462.1 - 1.6e-18 66.9 6.3 5.9e-10 39.4 1.8 3.6 4 1 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ25462.1 - 7.5e-10 39.3 3.9 5.9e-07 30.0 0.1 3.1 3 0 0 3 3 3 2 HMG-box domain DUF3106 PF11304.8 OAJ25462.1 - 0.093 13.2 13.5 0.19 12.2 2.3 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) Cation_efflux PF01545.21 OAJ25463.1 - 5.7e-18 65.4 10.8 7.1e-18 65.1 10.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ25463.1 - 7.9e-09 35.5 0.4 1.3e-08 34.9 0.4 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Ras PF00071.22 OAJ25464.1 - 8.8e-28 96.9 0.0 1.7e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OAJ25464.1 - 8.6e-26 90.5 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ25464.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ25464.1 - 0.0036 17.4 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ25464.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DNA_binding_1 PF01035.20 OAJ25465.1 - 2.2e-07 30.9 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Actin PF00022.19 OAJ25466.1 - 1.8e-23 82.8 0.0 3.2e-21 75.4 0.0 3.1 4 0 0 4 4 4 2 Actin MelC1 PF06236.11 OAJ25466.1 - 0.073 13.2 5.1 0.08 13.0 2.5 2.3 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Myb_DNA-binding PF00249.31 OAJ25467.1 - 2.4e-32 110.9 1.3 7.3e-17 61.3 1.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ25467.1 - 2.1e-20 72.7 0.0 1.3e-15 57.4 0.1 4.5 2 1 2 4 4 4 3 Myb-like DNA-binding domain Presenilin PF01080.17 OAJ25467.1 - 2.4e-05 23.3 17.3 2.4e-05 23.3 17.3 2.8 3 0 0 3 3 3 1 Presenilin PAT1 PF09770.9 OAJ25467.1 - 0.022 13.1 65.7 0.003 15.9 46.2 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spore_III_AB PF09548.10 OAJ25467.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.2 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GAGA_bind PF06217.12 OAJ25467.1 - 3.5 7.8 36.5 6 7.1 5.2 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family SecE PF00584.20 OAJ25468.1 - 3.5e-15 55.7 0.0 3.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CD24 PF14984.6 OAJ25469.1 - 0.16 12.2 8.0 1.5 9.1 7.7 2.8 2 0 0 2 2 2 0 CD24 protein ECH_1 PF00378.20 OAJ25470.1 - 4.7e-37 127.6 0.1 1.6e-36 125.9 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ25470.1 - 1.1e-20 74.4 0.1 7e-20 71.8 0.0 1.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PNP_UDP_1 PF01048.20 OAJ25471.1 - 1.5e-25 89.8 0.1 1.8e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Csm1 PF12539.8 OAJ25472.1 - 8.8e-09 35.9 0.0 7.4e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 LPP PF04728.13 OAJ25472.1 - 0.21 12.0 3.5 12 6.3 0.4 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Golgin_A5 PF09787.9 OAJ25472.1 - 0.36 10.3 27.6 1.1 8.7 18.6 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 OAJ25472.1 - 0.61 9.6 18.8 1.4 8.4 8.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 YopE_N PF09020.10 OAJ25472.1 - 0.68 10.2 4.5 0.34 11.2 0.4 2.4 2 0 0 2 2 2 0 YopE, N terminal TSC22 PF01166.18 OAJ25472.1 - 1.4 9.2 10.2 12 6.2 0.9 3.7 4 0 0 4 4 4 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 OAJ25472.1 - 1.7 8.8 23.5 1.1 9.3 7.0 2.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF1515 PF07439.11 OAJ25472.1 - 3.7 7.6 10.2 1.6 8.8 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Hamartin PF04388.12 OAJ25472.1 - 4.2 5.9 13.5 5 5.7 13.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3138 PF11336.8 OAJ25472.1 - 5.1 5.6 5.5 3 6.4 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) UPF0242 PF06785.11 OAJ25472.1 - 8.5 6.4 19.1 2 8.5 3.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TCTP PF00838.17 OAJ25473.1 - 8e-67 224.7 0.4 9e-67 224.6 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Methyltransf_16 PF10294.9 OAJ25474.1 - 7.6e-15 55.1 0.0 1.7e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 OAJ25474.1 - 0.1 13.3 0.2 36 5.1 0.0 2.7 1 1 0 2 2 2 0 Methyltransferase domain Ribosomal_S8e PF01201.22 OAJ25475.1 - 7.3e-54 181.6 1.3 8.8e-54 181.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SPO22 PF08631.10 OAJ25476.1 - 2.8e-10 40.2 0.1 2.8e-10 40.2 0.1 3.6 3 2 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 OAJ25476.1 - 1.7 9.4 6.1 5.3 7.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 OAJ25477.1 - 6.6e-45 153.0 0.0 1.5e-44 151.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ25477.1 - 9.3e-30 103.2 0.0 2e-27 95.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Borrelia_P83 PF05262.11 OAJ25477.1 - 0.043 12.3 13.4 0.054 12.0 13.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ERCC3_RAD25_C PF16203.5 OAJ25477.1 - 0.05 12.8 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Zip PF02535.22 OAJ25477.1 - 0.28 10.3 1.6 0.38 9.9 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OAJ25477.1 - 1.3 7.2 18.4 2 6.6 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 OAJ25478.1 - 0.0019 16.6 1.4 0.0026 16.1 1.4 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) KH_1 PF00013.29 OAJ25478.1 - 0.0053 16.6 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 KH domain PI3K_1B_p101 PF10486.9 OAJ25478.1 - 0.16 9.7 0.4 0.2 9.4 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_primase_lrg PF04104.14 OAJ25479.1 - 6.6e-82 274.9 0.0 1e-81 274.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pro_isomerase PF00160.21 OAJ25480.1 - 4.8e-37 127.7 0.0 3.9e-36 124.7 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 OAJ25480.1 - 0.057 13.9 0.1 0.057 13.9 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4604) LPP PF04728.13 OAJ25480.1 - 1.4 9.4 4.4 2.1 8.8 1.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Med26_C PF15693.5 OAJ25480.1 - 3.3 7.8 6.6 0.68 10.1 2.9 1.7 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal Aminotran_1_2 PF00155.21 OAJ25481.1 - 2.3e-20 73.1 0.0 5.4e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ25481.1 - 0.00041 19.0 0.0 0.0008 18.0 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TFB6 PF17110.5 OAJ25482.1 - 7.7 6.2 12.9 13 5.5 3.0 3.9 4 0 0 4 4 4 0 Subunit 11 of the general transcription factor TFIIH Glyco_hydro_92N PF17678.1 OAJ25484.1 - 8.6e-30 104.4 1.6 1.3e-29 103.8 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_92 PF07971.12 OAJ25485.1 - 4.3e-104 349.0 0.0 6e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ25485.1 - 1.9e-38 132.7 0.5 3.5e-38 131.9 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TFIIA PF03153.13 OAJ25486.1 - 9.1 6.1 24.8 11 5.8 9.0 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Snf7 PF03357.21 OAJ25487.1 - 1.8e-46 157.9 11.5 2.1e-46 157.7 11.5 1.0 1 0 0 1 1 1 1 Snf7 Soyouz_module PF14313.6 OAJ25487.1 - 0.025 14.3 0.1 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DMPK_coil PF08826.10 OAJ25487.1 - 0.11 12.7 0.3 0.11 12.7 0.3 3.6 4 0 0 4 4 4 0 DMPK coiled coil domain like NuA4 PF09340.10 OAJ25487.1 - 0.12 12.3 4.1 0.39 10.6 1.2 2.5 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF3091 PF11291.8 OAJ25487.1 - 0.14 12.3 1.1 0.41 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) Uso1_p115_C PF04871.13 OAJ25487.1 - 0.62 10.4 16.0 1.2 9.6 11.1 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RPW8 PF05659.11 OAJ25487.1 - 0.75 9.5 6.8 11 5.7 3.3 2.8 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5344 PF17279.2 OAJ25487.1 - 0.76 10.4 7.3 1.9 9.1 2.8 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5344) DUF848 PF05852.11 OAJ25487.1 - 1.3 9.1 10.8 1.2 9.2 8.1 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 OAJ25487.1 - 1.5 8.8 16.3 11 6.0 0.6 3.6 2 1 0 3 3 3 0 Prefoldin subunit AAA_23 PF13476.6 OAJ25487.1 - 1.7 9.1 6.0 2.3 8.7 6.0 1.2 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 OAJ25487.1 - 2.7 8.5 6.7 2.1 8.9 1.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 OAJ25487.1 - 4.7 7.7 8.5 19 5.7 0.1 3.4 3 2 1 4 4 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 OAJ25487.1 - 5.3 5.5 8.9 2 6.9 4.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A EMP24_GP25L PF01105.24 OAJ25487.1 - 7.7 6.4 6.9 11 5.9 0.0 2.8 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Nse4_C PF08743.10 OAJ25488.1 - 3.5e-29 100.9 0.2 1.1e-28 99.3 0.2 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAJ25488.1 - 4.3e-09 36.3 1.2 9.3e-09 35.3 1.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1351 PF07083.11 OAJ25488.1 - 0.016 15.0 0.7 0.016 15.0 0.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) DUF3391 PF11871.8 OAJ25488.1 - 5.8 7.5 7.6 16 6.1 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) ADH_N PF08240.12 OAJ25489.1 - 1.7e-26 92.2 0.3 1.7e-26 92.2 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ25489.1 - 4.8e-21 75.1 0.4 9.9e-21 74.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ25489.1 - 0.0025 18.8 0.3 0.0056 17.7 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAJ25489.1 - 0.014 14.9 0.4 0.034 13.6 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 OAJ25489.1 - 0.016 14.7 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACP_syn_III_C PF08541.10 OAJ25489.1 - 0.087 13.0 0.5 0.67 10.2 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Totivirus_coat PF05518.11 OAJ25490.1 - 6.8 4.6 16.0 9.5 4.1 16.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mito_carr PF00153.27 OAJ25496.1 - 2.5e-66 219.6 0.9 1.3e-22 79.6 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex14_N PF04695.13 OAJ25496.1 - 0.03 15.0 3.0 0.03 15.0 3.0 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 OAJ25496.1 - 1.3 7.7 3.0 2.2 7.0 3.0 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 OAJ25496.1 - 5.5 6.9 11.6 9.4 6.1 11.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 OAJ25497.1 - 2.8e-83 280.3 0.0 3.4e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) COG5 PF10392.9 OAJ25497.1 - 0.05 13.8 0.6 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 zf-ACC PF17848.1 OAJ25497.1 - 0.32 11.1 2.6 8.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain peroxidase PF00141.23 OAJ25499.1 - 2.9e-47 161.3 0.0 5.2e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF4231 PF14015.6 OAJ25500.1 - 1.6 9.2 15.0 4.3 7.9 5.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) RPA_interact_C PF14768.6 OAJ25501.1 - 0.01 16.4 0.3 0.035 14.7 0.0 2.0 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Hexapep PF00132.24 OAJ25502.1 - 1.2e-12 47.0 5.7 2.4e-10 39.7 3.2 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ25502.1 - 1.7e-12 46.8 7.0 1.7e-10 40.4 3.3 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OAJ25502.1 - 6.3e-07 29.5 0.0 2.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Maltose acetyltransferase Acyl_transf_1 PF00698.21 OAJ25503.1 - 2e-10 40.7 0.0 1.1e-05 25.1 0.0 2.9 1 1 1 2 2 2 2 Acyl transferase domain Hexapep_2 PF14602.6 OAJ25504.1 - 1.9e-11 43.5 2.8 5.9e-09 35.5 1.4 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OAJ25504.1 - 2.2e-11 43.0 1.7 4.2e-08 32.6 0.9 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OAJ25504.1 - 9.3e-10 38.6 0.3 3.4e-09 36.8 0.0 2.0 2 1 0 2 2 2 1 Maltose acetyltransferase Fungal_trans PF04082.18 OAJ25505.1 - 1.1e-06 28.0 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ25505.1 - 2.4e-06 27.5 10.4 3.9e-06 26.9 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAJ25506.1 - 5.1e-73 246.4 0.0 1.2e-70 238.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 PspB PF06667.12 OAJ25506.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B Co_AT_N PF12557.8 OAJ25506.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Peptidase_S41 PF03572.18 OAJ25506.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S41 ketoacyl-synt PF00109.26 OAJ25508.1 - 2.6e-74 250.0 0.0 5.1e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAJ25508.1 - 1.5e-43 149.5 0.0 1.3e-41 143.1 0.0 3.4 3 1 1 4 4 4 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAJ25508.1 - 1.8e-33 115.0 0.8 4.4e-33 113.8 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 OAJ25508.1 - 1.8e-27 96.4 0.0 3.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 OAJ25508.1 - 1.1e-23 84.3 4.8 1.1e-21 77.7 2.3 3.3 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 OAJ25508.1 - 2.2e-23 83.6 0.1 4.6e-22 79.3 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 OAJ25508.1 - 5.4e-15 55.5 3.3 2.2e-06 27.9 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 OAJ25508.1 - 8.7e-10 39.6 3.1 2.2e-08 35.0 0.1 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 OAJ25508.1 - 4.3e-07 30.4 0.0 1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 OAJ25508.1 - 0.00036 20.0 0.1 0.00089 18.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.7 OAJ25508.1 - 0.00084 19.1 0.1 0.091 12.5 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ25508.1 - 0.014 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ25508.1 - 0.078 12.8 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold ACP_syn_III PF08545.10 OAJ25508.1 - 0.1 12.5 1.3 0.54 10.1 0.4 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SUR7 PF06687.12 OAJ25509.1 - 2.2e-07 30.8 0.0 4.9e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 SUR7/PalI family HCMV_UL139 PF12507.8 OAJ25509.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF3112 PF11309.8 OAJ25509.1 - 0.52 9.7 6.3 0.075 12.5 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) ATF7IP_BD PF16788.5 OAJ25509.1 - 8 6.5 8.2 12 5.9 8.2 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Uso1_p115_head PF04869.14 OAJ25510.1 - 9.5e-43 146.5 0.0 4.3e-28 98.4 0.0 3.9 4 0 0 4 4 4 3 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAJ25510.1 - 1.3e-12 48.2 22.9 1.3e-12 48.2 22.9 3.5 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Atx10homo_assoc PF09759.9 OAJ25510.1 - 0.0074 16.3 3.6 0.08 13.0 0.0 3.6 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Cep57_MT_bd PF06657.13 OAJ25510.1 - 3.4 8.2 22.0 0.14 12.6 1.2 4.0 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 RabGAP-TBC PF00566.18 OAJ25511.1 - 8.8e-51 172.6 0.0 1.1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_2 PF00891.18 OAJ25512.1 - 1.2e-24 86.7 0.0 3.8e-24 85.2 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 OAJ25512.1 - 0.014 15.2 0.2 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain MTS PF05175.14 OAJ25512.1 - 0.061 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 OAJ25512.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase HTH_31 PF13560.6 OAJ25512.1 - 0.13 12.7 0.7 2.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Methyltransf_2 PF00891.18 OAJ25513.1 - 0.0061 15.9 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain GSDH PF07995.11 OAJ25514.1 - 4.2e-05 23.0 0.1 0.00012 21.5 0.1 1.7 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Aldo_ket_red PF00248.21 OAJ25515.1 - 2e-50 171.7 0.0 2.3e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.31 OAJ25516.1 - 3.4e-29 100.8 6.2 7.8e-10 38.8 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ25516.1 - 2.5e-23 82.1 2.3 1.8e-10 40.9 0.0 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain DUF2722 PF10846.8 OAJ25516.1 - 2.7e-05 23.3 32.1 0.0093 15.0 3.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.8 OAJ25516.1 - 0.00021 21.0 41.0 0.013 15.1 5.5 2.3 2 0 0 2 2 2 2 Spt20 family ANAPC_CDC26 PF10471.9 OAJ25516.1 - 0.15 12.9 40.0 0.51 11.2 23.4 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4471 PF14740.6 OAJ25516.1 - 0.21 10.8 5.9 2.2 7.4 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) MAP65_ASE1 PF03999.12 OAJ25516.1 - 0.23 10.1 30.5 0.012 14.4 12.6 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) EOS1 PF12326.8 OAJ25516.1 - 0.36 10.7 4.6 0.85 9.5 0.3 2.2 2 0 0 2 2 2 0 N-glycosylation protein MecA PF05389.12 OAJ25516.1 - 0.39 10.3 9.5 0.28 10.8 1.9 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) BRF1 PF07741.13 OAJ25516.1 - 0.41 11.0 9.6 1.7 9.0 2.2 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Band_3_cyto PF07565.13 OAJ25516.1 - 0.43 10.3 12.2 1.2 8.9 5.3 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CPSF100_C PF13299.6 OAJ25516.1 - 0.43 10.7 13.0 1.1 9.4 3.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Draxin PF15550.6 OAJ25516.1 - 0.51 10.1 12.2 0.14 12.0 4.5 2.3 2 0 0 2 2 2 0 Draxin Afi1 PF07792.12 OAJ25516.1 - 0.79 10.2 11.9 0.56 10.7 6.0 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 OAJ25516.1 - 0.79 9.5 12.2 0.7 9.7 3.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MPM1 PF17234.2 OAJ25516.1 - 0.82 9.9 13.9 1.2 9.4 6.7 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Suf PF05843.14 OAJ25516.1 - 0.87 9.5 25.5 2.6 8.0 3.4 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 OAJ25516.1 - 0.94 8.9 15.7 0.75 9.2 6.4 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 OAJ25516.1 - 1.2 9.1 23.3 2.3 8.2 12.0 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Tim54 PF11711.8 OAJ25516.1 - 1.3 7.7 17.6 2 7.1 6.5 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CCDC53 PF10152.9 OAJ25516.1 - 1.4 9.3 18.2 2.4 8.5 3.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3408 PF11888.8 OAJ25516.1 - 1.4 9.0 21.4 0.63 10.2 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Clathrin_lg_ch PF01086.17 OAJ25516.1 - 1.5 8.8 20.7 3.2 7.7 0.7 3.2 3 0 0 3 3 3 0 Clathrin light chain Lin-8 PF03353.15 OAJ25516.1 - 1.7 8.2 27.8 1.7 8.1 14.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EPL1 PF10513.9 OAJ25516.1 - 1.7 9.0 17.0 3.7 7.9 8.4 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM60A PF15396.6 OAJ25516.1 - 1.7 8.6 12.3 5.2 7.0 3.7 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Serinc PF03348.15 OAJ25516.1 - 1.9 7.3 6.5 0.25 10.3 0.5 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) TFB6 PF17110.5 OAJ25516.1 - 2.2 8.0 7.2 2 8.2 2.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH V_ATPase_I PF01496.19 OAJ25516.1 - 2.3 6.0 11.1 5.8 4.7 7.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Rxt3 PF08642.10 OAJ25516.1 - 2.4 9.0 9.7 5.6 7.7 1.8 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Zip PF02535.22 OAJ25516.1 - 2.5 7.3 5.9 0.63 9.2 1.2 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Hydin_ADK PF17213.3 OAJ25516.1 - 2.5 8.4 21.2 3 8.1 4.2 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain PAT1 PF09770.9 OAJ25516.1 - 2.7 6.2 33.7 2.1 6.5 4.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 NST1 PF13945.6 OAJ25516.1 - 2.7 8.1 20.5 5.8 7.0 11.5 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF4770 PF15994.5 OAJ25516.1 - 3.8 7.7 19.5 8.1 6.6 10.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RPA43_OB PF17875.1 OAJ25516.1 - 4.5 7.9 9.9 4.6 7.9 3.7 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Eapp_C PF10238.9 OAJ25516.1 - 4.5 7.3 15.4 5 7.2 7.4 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Pet20 PF08692.10 OAJ25516.1 - 5.2 7.8 7.9 3.4 8.4 2.5 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Plasmodium_Vir PF05795.11 OAJ25516.1 - 5.3 6.4 13.3 1.3 8.3 1.9 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Thg1C PF14413.6 OAJ25516.1 - 5.5 7.2 16.7 2.6 8.2 1.7 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain DUF4834 PF16118.5 OAJ25516.1 - 7 7.7 23.2 13 6.9 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF702 PF05142.12 OAJ25516.1 - 7.1 7.1 18.5 11 6.5 7.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) CTU2 PF10288.9 OAJ25516.1 - 8.6 6.7 15.2 7.2 6.9 5.3 2.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF3801 PF12687.7 OAJ25516.1 - 8.9 6.3 16.7 8.1 6.5 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) adh_short PF00106.25 OAJ25518.1 - 8.1e-32 110.3 1.9 1.3e-31 109.6 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ25518.1 - 9.5e-25 87.5 1.3 1.4e-24 87.0 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ25518.1 - 9.7e-09 35.4 0.5 1.4e-08 34.9 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAJ25518.1 - 6.1e-06 26.3 1.0 7.7e-06 25.9 1.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ25518.1 - 9.3e-06 25.3 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ25518.1 - 0.0045 16.4 0.1 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 OAJ25518.1 - 0.077 13.3 0.4 0.14 12.4 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 OAJ25519.1 - 8.2e-62 209.5 0.0 1.1e-61 209.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ25519.1 - 1.2e-05 24.7 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 OAJ25519.1 - 0.00037 20.6 0.0 0.00064 19.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 OAJ25519.1 - 0.00045 20.4 0.1 0.0013 18.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ25519.1 - 0.00052 20.5 0.1 0.0018 18.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ25519.1 - 0.00056 19.6 1.1 0.037 13.6 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ25519.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAJ25519.1 - 0.0027 16.9 0.3 0.0049 16.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ25519.1 - 0.0036 16.4 0.4 0.0059 15.7 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAJ25519.1 - 0.0053 15.5 0.3 0.0083 14.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAJ25519.1 - 0.033 13.3 0.4 0.05 12.7 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAJ25519.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ25519.1 - 0.28 10.5 0.3 0.41 9.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Myb_DNA-binding PF00249.31 OAJ25520.1 - 1.8e-28 98.5 5.5 8.2e-10 38.7 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ25520.1 - 1.4e-23 82.9 1.7 1.9e-10 40.8 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Serinc PF03348.15 OAJ25520.1 - 0.58 9.0 2.4 0.97 8.3 2.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Rap1_C PF11626.8 OAJ25520.1 - 0.61 10.2 5.8 4.9 7.3 0.0 3.7 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Clathrin_lg_ch PF01086.17 OAJ25520.1 - 1.7 8.7 15.1 1.2 9.1 1.0 3.0 3 0 0 3 3 3 0 Clathrin light chain TERB2 PF15101.6 OAJ25520.1 - 3.2 7.8 15.8 3 7.9 9.7 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 SMODS PF18144.1 OAJ25521.1 - 0.043 14.0 0.0 0.056 13.6 0.0 1.3 1 1 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain SnoaL PF07366.12 OAJ25521.1 - 0.17 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase CDC37_N PF03234.14 OAJ25527.1 - 2.4e-35 122.3 2.3 4e-35 121.5 0.0 2.4 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 OAJ25527.1 - 3.8e-19 68.7 0.0 9.5e-19 67.5 0.0 1.6 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAJ25527.1 - 3.4e-15 56.0 0.3 1.1e-14 54.3 0.1 2.0 2 0 0 2 2 2 1 Cdc37 C terminal domain CENP-L PF13092.6 OAJ25527.1 - 0.07 13.3 0.4 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 DFRP_C PF16543.5 OAJ25527.1 - 0.75 10.3 4.4 1.1 9.8 0.2 2.6 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 NUDE_C PF04880.13 OAJ25528.1 - 0.49 10.9 5.6 0.77 10.2 4.8 1.7 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DivIC PF04977.15 OAJ25528.1 - 4 7.3 6.3 7.7 6.4 6.3 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF2721 PF11026.8 OAJ25529.1 - 0.35 10.8 1.5 0.62 10.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Syntaxin PF00804.25 OAJ25529.1 - 0.4 10.3 4.6 0.68 9.6 4.6 1.3 1 0 0 1 1 1 0 Syntaxin LSM14 PF12701.7 OAJ25532.1 - 8.4e-26 89.9 0.0 1.3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OAJ25532.1 - 1.2e-06 29.4 3.6 1.3e-06 29.2 0.0 2.7 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 OAJ25532.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain F-box PF00646.33 OAJ25533.1 - 2.5e-05 24.0 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain Abhydrolase_5 PF12695.7 OAJ25534.1 - 0.041 13.6 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family TMEM101 PF15111.6 OAJ25536.1 - 0.029 13.9 0.2 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 TMEM101 protein family NOG1_N PF17835.1 OAJ25537.1 - 1.5e-45 155.0 0.5 2.9e-45 154.1 0.5 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAJ25537.1 - 6.3e-28 96.5 3.4 1.6e-27 95.3 3.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAJ25537.1 - 2.3e-27 94.5 0.1 4.4e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAJ25537.1 - 2.6e-19 69.4 0.0 7.6e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ25537.1 - 1.1e-09 38.0 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ25537.1 - 0.00024 21.2 0.0 0.51 10.4 0.0 2.8 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 OAJ25537.1 - 0.0045 16.9 0.0 0.32 10.9 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 OAJ25537.1 - 0.033 14.4 0.0 0.2 11.9 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OAJ25537.1 - 0.056 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 OAJ25537.1 - 0.087 13.4 0.1 1.5 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.10 OAJ25537.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAJ25537.1 - 0.12 12.8 0.0 0.39 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain RR_TM4-6 PF06459.12 OAJ25537.1 - 0.58 9.9 6.6 1.3 8.8 6.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GST_N_3 PF13417.6 OAJ25538.1 - 2.4e-12 47.1 0.0 4.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ25538.1 - 4.5e-10 39.7 0.0 9.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ25538.1 - 0.00015 21.7 0.8 0.00024 21.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAJ25538.1 - 0.0057 17.4 0.0 0.041 14.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 OAJ25538.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WW PF00397.26 OAJ25539.1 - 5.4e-08 32.8 6.7 3.8e-07 30.1 6.4 2.2 2 0 0 2 2 2 1 WW domain Peptidase_M43 PF05572.13 OAJ25541.1 - 2.3e-18 66.5 0.0 3.6e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ25541.1 - 0.0021 18.5 1.1 0.014 15.9 0.2 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ25541.1 - 0.033 14.3 2.2 0.057 13.6 2.2 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 OAJ25541.1 - 0.085 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 OAJ25541.1 - 0.09 12.6 1.0 0.11 12.3 1.0 1.5 1 1 0 1 1 1 0 Matrixin DS PF01916.17 OAJ25541.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF4854 PF16146.5 OAJ25541.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Fringe PF02434.16 OAJ25542.1 - 5.8e-09 35.8 0.4 3.4e-08 33.2 0.4 2.2 1 1 0 1 1 1 1 Fringe-like YjeF_N PF03853.15 OAJ25543.1 - 3.4e-34 118.2 0.0 4.8e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Acetyltransf_1 PF00583.25 OAJ25544.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ25544.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BST2 PF16716.5 OAJ25547.1 - 0.0012 19.4 4.4 0.018 15.6 0.0 2.8 2 1 0 2 2 2 1 Bone marrow stromal antigen 2 Myosin_tail_1 PF01576.19 OAJ25547.1 - 0.0067 14.3 15.4 0.04 11.8 15.5 1.8 1 1 0 1 1 1 1 Myosin tail Fzo_mitofusin PF04799.13 OAJ25547.1 - 0.0081 15.7 0.5 0.013 15.1 0.4 1.4 1 1 0 1 1 1 1 fzo-like conserved region ATG_C PF09333.11 OAJ25547.1 - 0.0085 16.4 3.0 0.19 12.1 0.1 3.2 1 1 2 3 3 3 1 Autophagy-related protein C terminal domain Laminin_II PF06009.12 OAJ25547.1 - 0.028 14.4 10.2 0.82 9.7 0.2 2.5 1 1 1 2 2 2 0 Laminin Domain II MAD PF05557.13 OAJ25547.1 - 0.11 10.8 6.2 0.13 10.6 6.2 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Orbi_NS1 PF01718.16 OAJ25547.1 - 0.23 9.9 0.8 0.27 9.6 0.8 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Cep57_MT_bd PF06657.13 OAJ25547.1 - 0.3 11.6 2.7 0.42 11.1 0.1 2.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ISG65-75 PF11727.8 OAJ25547.1 - 0.68 9.1 10.1 0.67 9.1 8.6 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF2968 PF11180.8 OAJ25547.1 - 0.89 9.2 9.2 0.16 11.6 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF2514 PF10721.9 OAJ25547.1 - 1.5 8.8 22.7 4 7.4 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Sec2p PF06428.11 OAJ25547.1 - 3 7.9 12.6 1.4 8.9 6.4 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 OAJ25547.1 - 3.3 7.0 14.6 4.5 6.6 14.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPRTase PF14681.6 OAJ25549.1 - 9.5e-64 214.7 0.0 1.1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAJ25549.1 - 2.4e-05 23.9 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ras PF00071.22 OAJ25550.1 - 3e-58 196.0 0.2 3.4e-58 195.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ25550.1 - 5.4e-20 71.8 0.0 9.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ25550.1 - 4.2e-08 32.8 0.0 5.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ25550.1 - 0.00012 21.6 0.1 0.00026 20.6 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ25550.1 - 0.00025 21.0 0.0 0.19 11.6 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ25550.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ25550.1 - 0.04 13.5 0.1 0.11 12.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OAJ25550.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain CbiA PF01656.23 OAJ25550.1 - 0.18 11.9 0.5 1.9 8.5 0.5 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Transposase_21 PF02992.14 OAJ25551.1 - 8.3e-05 21.9 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Regnase_1_C PF18561.1 OAJ25551.1 - 0.031 14.0 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Gemin7 PF11095.8 OAJ25551.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF948 PF06103.11 OAJ25552.1 - 0.36 11.1 2.6 0.71 10.2 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec10 PF07393.11 OAJ25553.1 - 1.7e-238 793.7 0.0 2.1e-238 793.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Spc7 PF08317.11 OAJ25553.1 - 0.0037 16.2 0.1 0.0067 15.3 0.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 OAJ25553.1 - 0.019 15.0 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2959 PF11172.8 OAJ25553.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF812 PF05667.11 OAJ25553.1 - 0.27 10.1 2.5 0.69 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DNA_ligase_A_N PF04675.14 OAJ25554.1 - 3.4e-16 60.1 0.1 8.8e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus MurB_C PF02873.16 OAJ25554.1 - 0.16 12.0 1.3 0.43 10.7 1.3 1.6 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Polysacc_deac_1 PF01522.21 OAJ25555.1 - 1.5e-21 76.6 0.0 4.3e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase EHN PF06441.12 OAJ25556.1 - 2.3e-24 85.8 0.0 4.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ25556.1 - 7.4e-10 38.9 0.1 1.3e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ25556.1 - 0.0013 19.4 5.2 0.0013 19.4 5.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family SRP54 PF00448.22 OAJ25562.1 - 1.3e-74 250.2 0.3 1.3e-74 250.2 0.3 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAJ25562.1 - 1.5e-28 99.3 0.1 1.5e-28 99.3 0.1 3.6 3 1 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 OAJ25562.1 - 2.6e-16 59.6 2.2 5.2e-16 58.6 2.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 OAJ25562.1 - 0.00013 21.6 0.9 0.002 17.8 0.9 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAJ25562.1 - 0.0012 19.1 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAJ25562.1 - 0.0053 17.2 0.0 0.0053 17.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 OAJ25562.1 - 0.022 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 OAJ25562.1 - 0.032 14.5 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ25562.1 - 0.054 13.9 1.1 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OAJ25562.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAJ25562.1 - 0.097 12.8 0.1 0.42 10.7 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 OAJ25562.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 OAJ25562.1 - 0.15 11.5 0.2 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 OAJ25562.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAJ25562.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAJ25562.1 - 0.18 11.8 0.5 2.7 8.0 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 OAJ25562.1 - 0.27 10.8 1.8 0.81 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain CALM_bind PF16025.5 OAJ25562.1 - 7.6 7.1 7.2 5.3 7.6 0.6 3.2 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding Pet191_N PF10203.9 OAJ25563.1 - 2.9e-24 85.1 2.6 3.4e-24 84.9 2.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CCT PF06203.14 OAJ25563.1 - 0.063 13.3 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 CCT motif Prefoldin PF02996.17 OAJ25564.1 - 1.4e-26 92.7 0.1 1.8e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OAJ25564.1 - 0.018 15.0 0.2 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1192 PF06698.11 OAJ25564.1 - 0.038 14.0 2.8 0.27 11.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 OAJ25564.1 - 0.046 13.8 0.2 4.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nas2_N PF18265.1 OAJ25564.1 - 0.15 12.0 0.5 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Nas2 N_terminal domain GAS PF13851.6 OAJ25564.1 - 0.16 11.3 2.6 2.4 7.5 0.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GATA PF00320.27 OAJ25565.1 - 1.3e-26 91.9 21.2 5.1e-14 51.6 4.7 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 OAJ25565.1 - 4.1e-09 36.1 0.3 7.4e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 OAJ25565.1 - 0.0022 17.5 7.2 0.049 13.1 1.5 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 OAJ25565.1 - 0.2 11.7 6.8 4.2 7.5 7.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAJ25565.1 - 0.3 11.2 7.1 0.67 10.1 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 OAJ25565.1 - 0.45 10.5 7.8 6.1 6.9 0.7 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 OAJ25565.1 - 1.7 8.9 11.4 0.61 10.3 0.6 2.7 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-piccolo PF05715.13 OAJ25565.1 - 2.6 8.3 11.5 3.1 8.0 1.3 3.4 2 1 1 3 3 3 0 Piccolo Zn-finger eIF-5_eIF-2B PF01873.17 OAJ25565.1 - 7.1 6.5 9.6 2.7 7.9 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF3384 PF11864.8 OAJ25566.1 - 1.8e-59 202.0 0.0 2.1e-58 198.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 OAJ25566.1 - 1.5e-42 145.2 0.0 2.6e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 OAJ25566.1 - 2.1e-31 109.3 4.7 2.9e-28 99.0 4.8 3.0 2 1 0 2 2 2 2 Tuberin FAD_binding_7 PF03441.14 OAJ25567.1 - 1.6e-54 184.4 1.0 2.6e-54 183.8 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ25567.1 - 2.4e-19 70.0 0.0 4.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Lysine_decarbox PF03641.14 OAJ25568.1 - 7.3e-33 113.5 0.0 9.6e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAJ25568.1 - 3.2e-10 39.8 2.1 8.6e-10 38.4 2.1 1.8 1 1 0 1 1 1 1 SLOG cluster4 family HMG-CoA_red PF00368.18 OAJ25569.1 - 7.3e-140 466.1 8.6 1.1e-139 465.6 8.6 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 OAJ25569.1 - 5.2e-20 71.8 1.0 1.3e-09 38.1 0.2 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAJ25569.1 - 9.6e-06 24.0 2.9 0.0012 17.0 0.0 2.2 2 0 0 2 2 2 2 Patched family HPIH PF13323.6 OAJ25569.1 - 2.2 8.1 6.4 0.15 11.9 0.3 2.2 3 0 0 3 3 3 0 N-terminal domain with HPIH motif ubiquitin PF00240.23 OAJ25570.1 - 6.7e-34 115.5 0.7 9.4e-34 115.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ25570.1 - 4.7e-16 58.4 0.8 7.2e-16 57.8 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 OAJ25570.1 - 5.9e-10 39.1 5.5 1e-09 38.4 5.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 OAJ25570.1 - 3.2e-05 24.3 0.2 0.00012 22.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ25570.1 - 0.0033 17.5 0.4 0.014 15.5 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAJ25570.1 - 0.0061 16.5 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ25570.1 - 0.0072 16.7 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OAJ25570.1 - 0.019 15.5 0.1 0.024 15.2 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ25570.1 - 0.023 14.7 1.1 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ25570.1 - 0.096 12.5 0.9 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain HSA PF07529.13 OAJ25571.1 - 4.2e-12 46.2 2.9 4.2e-12 46.2 2.9 4.7 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 OAJ25571.1 - 4.5e-08 33.2 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ25571.1 - 0.0036 17.5 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ25571.1 - 0.034 14.3 0.2 0.034 14.3 0.2 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 GMC_oxred_N PF00732.19 OAJ25573.1 - 3e-39 135.1 0.0 4.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ25573.1 - 9.6e-21 74.8 0.3 3.7e-20 72.9 0.1 2.1 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ25573.1 - 3.5e-09 36.2 1.7 2.2e-05 23.7 1.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ25573.1 - 3.4e-05 24.0 0.3 7.4e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAJ25573.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAJ25573.1 - 0.00019 21.2 0.5 0.014 15.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ25573.1 - 0.0025 17.1 0.2 0.0063 15.8 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ25573.1 - 0.0089 15.4 1.4 0.013 14.9 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ25573.1 - 0.014 14.1 0.3 0.03 13.0 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein FliG_M PF14841.6 OAJ25573.1 - 0.033 14.4 0.2 0.073 13.3 0.0 1.6 2 0 0 2 2 1 0 FliG middle domain Thi4 PF01946.17 OAJ25573.1 - 0.044 13.0 0.3 0.092 12.0 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ25573.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAJ25573.1 - 0.092 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 OAJ25573.1 - 0.23 11.1 0.6 0.41 10.3 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA eIF-6 PF01912.18 OAJ25574.1 - 3.9e-79 264.6 0.3 4.5e-79 264.4 0.3 1.0 1 0 0 1 1 1 1 eIF-6 family MULE PF10551.9 OAJ25575.1 - 2.9e-12 46.8 0.0 1.3e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ25575.1 - 0.03 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family TT_ORF2 PF02957.15 OAJ25575.1 - 0.037 14.9 2.1 0.11 13.4 2.1 1.8 1 0 0 1 1 1 0 TT viral ORF2 Sigma70_ner PF04546.13 OAJ25575.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 OAJ25576.1 - 0.62 8.2 10.9 0.12 10.5 0.6 2.2 2 0 0 2 2 2 0 Nop14-like family Myb_DNA-bind_4 PF13837.6 OAJ25577.1 - 3e-05 24.3 0.3 5.5e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FAD_binding_6 PF00970.24 OAJ25578.1 - 3.8e-06 27.2 0.0 2.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ25578.1 - 4.4e-05 24.1 0.0 0.031 14.9 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain DAGK_cat PF00781.24 OAJ25578.1 - 0.13 11.9 0.1 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF1206 PF06724.11 OAJ25578.1 - 0.2 11.8 2.9 0.32 11.1 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) MgtE PF01769.16 OAJ25579.1 - 0.0064 16.9 4.7 0.065 13.6 0.5 2.6 2 0 0 2 2 2 2 Divalent cation transporter HemX PF04375.14 OAJ25579.1 - 0.52 9.5 7.9 0.31 10.3 5.7 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4478 PF14793.6 OAJ25580.1 - 0.79 9.6 5.5 0.12 12.3 0.7 2.2 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Ank_4 PF13637.6 OAJ25581.1 - 3.3e-05 24.3 0.0 0.00016 22.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ25581.1 - 0.0019 18.7 0.0 0.0089 16.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ25581.1 - 0.009 16.4 0.1 0.7 10.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OAJ25581.1 - 0.077 13.6 0.1 1.5 9.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat DEC-1_N PF04625.13 OAJ25581.1 - 0.098 11.6 4.7 0.11 11.4 4.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glycogen_syn PF05693.13 OAJ25582.1 - 0 1130.7 0.0 0 1130.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 OAJ25582.1 - 9.8e-08 31.7 0.0 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAJ25582.1 - 2.9e-06 27.2 0.1 7.7e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 OAJ25582.1 - 3.3e-06 27.6 0.0 0.0045 17.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ25582.1 - 4.1e-05 23.7 0.2 7.6e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAJ25582.1 - 0.00019 21.9 0.0 0.00043 20.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Caleosin PF05042.13 OAJ25583.1 - 2.2e-65 219.7 0.2 2.7e-65 219.4 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein FA_desaturase PF00487.24 OAJ25589.1 - 1.2e-22 81.0 18.9 1.3e-22 80.9 16.8 1.8 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 OAJ25589.1 - 4.7e-17 61.2 0.2 8.1e-17 60.4 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) MULE PF10551.9 OAJ25590.1 - 1.6e-11 44.5 0.0 3.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ25590.1 - 0.0016 17.4 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family RVT_2 PF07727.14 OAJ25591.1 - 6.8e-72 242.0 0.0 9.5e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ25591.1 - 1.5e-15 57.4 0.0 5.4e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ25591.1 - 2.6e-05 24.0 0.3 5.9e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Integrase_H2C2 PF17921.1 OAJ25591.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Retrotran_gag_2 PF14223.6 OAJ25592.1 - 2.6e-05 23.9 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OAJ25592.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ25592.1 - 0.24 11.5 2.2 0.51 10.5 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle 4HBT_3 PF13622.6 OAJ25593.1 - 1.1e-29 104.4 0.6 1.7e-29 103.8 0.6 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MBOAT PF03062.19 OAJ25594.1 - 2.5e-38 132.3 17.9 1.6e-37 129.7 14.5 2.9 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family WD40 PF00400.32 OAJ25597.1 - 7.6e-12 45.6 3.8 0.18 12.8 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Spt20 PF12090.8 OAJ25598.1 - 0.77 9.3 6.2 0.43 10.2 3.0 2.0 2 0 0 2 2 2 0 Spt20 family Yae1_N PF09811.9 OAJ25599.1 - 0.94 9.2 8.6 0.2 11.4 0.8 2.6 2 1 0 2 2 2 0 Essential protein Yae1, N terminal SRP-alpha_N PF04086.13 OAJ25599.1 - 2.1 8.2 14.0 2.3 8.0 14.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MDFI PF15316.6 OAJ25599.1 - 3.3 7.8 4.4 4.8 7.2 4.4 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Orn_Arg_deC_N PF02784.16 OAJ25600.1 - 1.4e-73 247.3 0.0 1.9e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAJ25600.1 - 1.2e-14 54.3 0.0 2.5e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 OAJ25600.1 - 0.05 13.6 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain zf-C2H2_jaz PF12171.8 OAJ25601.1 - 6.6e-10 39.0 1.8 1.1e-09 38.3 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ25601.1 - 7.2e-05 23.0 1.2 0.00011 22.4 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAJ25601.1 - 0.0011 19.2 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Bot1p PF12298.8 OAJ25601.1 - 0.044 14.0 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein AKAP95 PF04988.12 OAJ25601.1 - 0.098 12.9 1.1 0.16 12.2 0.9 1.4 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Catalase PF00199.19 OAJ25602.1 - 2.1e-187 622.9 0.2 2.6e-187 622.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ25602.1 - 9.5e-20 70.6 0.0 2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF5053 PF16476.5 OAJ25602.1 - 0.089 12.5 0.3 42 3.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) PTR2 PF00854.21 OAJ25603.1 - 7.3e-82 275.3 8.6 1.1e-81 274.7 8.6 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAJ25604.1 - 7.7e-22 77.7 20.1 1.1e-21 77.2 20.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ25604.1 - 6.7e-07 28.5 10.7 9.6e-07 28.0 10.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter HLH PF00010.26 OAJ25605.1 - 1.5e-07 31.3 0.3 2.6e-07 30.5 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 OAJ25605.1 - 0.00099 19.2 18.2 0.039 14.0 6.6 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 OAJ25605.1 - 0.0066 15.9 1.5 0.011 15.2 1.5 1.4 1 0 0 1 1 1 1 SDA1 RNA_pol_3_Rpc31 PF11705.8 OAJ25605.1 - 0.026 14.8 13.5 0.19 12.0 6.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAJ25605.1 - 0.072 11.3 5.0 0.12 10.5 5.0 1.3 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 OAJ25605.1 - 0.19 11.5 2.8 0.46 10.2 2.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein COPI_C PF06957.11 OAJ25605.1 - 0.29 9.9 1.1 0.52 9.0 1.1 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PBP1_TM PF14812.6 OAJ25605.1 - 6.5 7.2 11.9 21 5.6 11.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L38e PF01781.18 OAJ25606.1 - 5e-34 116.2 0.4 6.5e-34 115.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family IBN_N PF03810.19 OAJ25607.1 - 1.3e-05 25.0 0.0 6.6e-05 22.7 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 OAJ25607.1 - 0.07 13.4 2.6 21 5.7 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat polyprenyl_synt PF00348.17 OAJ25608.1 - 7.8e-61 205.4 0.0 3.1e-34 118.2 0.0 3.0 2 2 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OAJ25608.1 - 0.042 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Clat_adaptor_s PF01217.20 OAJ25609.1 - 1.3e-54 184.0 0.2 1.5e-54 183.8 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PAXNEB PF05625.11 OAJ25611.1 - 6.9e-29 101.1 0.0 3.6e-25 88.9 0.0 3.6 2 1 0 2 2 2 2 PAXNEB protein PPR_1 PF12854.7 OAJ25613.1 - 0.0057 16.3 0.1 0.0095 15.6 0.1 1.3 1 0 0 1 1 1 1 PPR repeat PPR PF01535.20 OAJ25613.1 - 0.01 16.0 0.0 0.063 13.5 0.0 2.2 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 OAJ25613.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family Ribosomal_S11 PF00411.19 OAJ25614.1 - 2.9e-43 146.7 1.0 4.4e-43 146.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 MBOAT PF03062.19 OAJ25615.1 - 3e-52 178.1 20.0 3e-52 178.1 20.0 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family AdoHcyase PF05221.17 OAJ25616.1 - 3.8e-133 443.2 0.0 1.7e-74 250.7 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAJ25616.1 - 6.7e-83 276.6 2.1 1e-82 276.0 2.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAJ25616.1 - 1e-08 34.8 0.1 2e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAJ25616.1 - 0.00075 19.1 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAJ25616.1 - 0.0039 17.4 0.1 0.0086 16.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 OAJ25616.1 - 0.065 13.7 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding IBN_N PF03810.19 OAJ25622.1 - 1.6e-13 50.4 0.0 1.5e-12 47.2 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 OAJ25622.1 - 1.4e-07 30.7 0.0 3.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 OAJ25622.1 - 2.5e-05 24.4 0.8 0.001 19.1 0.0 2.9 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 OAJ25622.1 - 0.011 16.1 10.7 0.22 12.0 0.0 4.3 5 0 0 5 5 5 0 HEAT repeats HTH_psq PF05225.16 OAJ25622.1 - 0.017 14.8 0.3 0.042 13.6 0.3 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Vac14_Fab1_bd PF12755.7 OAJ25622.1 - 0.034 14.7 0.1 1.6 9.4 0.0 3.8 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region XPC-binding PF09280.11 OAJ25622.1 - 0.073 12.8 0.1 0.35 10.6 0.1 2.2 1 0 0 1 1 1 0 XPC-binding domain AAA PF00004.29 OAJ25623.1 - 1.9e-96 319.5 0.0 4e-47 159.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ25623.1 - 3.4e-25 87.6 8.2 2e-12 46.7 0.4 3.1 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 OAJ25623.1 - 7.9e-21 74.0 0.1 3.1e-20 72.1 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OAJ25623.1 - 2.1e-14 53.6 0.0 2.1e-05 24.4 0.0 3.7 3 2 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAJ25623.1 - 5.5e-13 49.4 0.0 4.2e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ25623.1 - 4.2e-12 46.4 0.0 4.7e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ25623.1 - 2.9e-11 43.5 0.4 2.6e-05 24.2 0.1 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 OAJ25623.1 - 1.6e-10 40.6 0.0 3.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 OAJ25623.1 - 5.2e-10 40.0 0.4 0.0018 18.6 0.0 4.3 3 2 0 3 3 2 2 AAA ATPase domain Vps4_C PF09336.10 OAJ25623.1 - 1.2e-09 38.0 0.4 1e-08 35.0 0.1 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 OAJ25623.1 - 2.6e-09 36.8 0.0 0.0017 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OAJ25623.1 - 7.4e-09 36.0 0.1 0.021 15.1 0.0 3.9 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OAJ25623.1 - 4.6e-08 32.7 0.4 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ25623.1 - 3.9e-07 30.0 0.0 0.018 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OAJ25623.1 - 6.6e-07 29.9 0.0 0.011 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OAJ25623.1 - 1.2e-06 28.6 0.0 0.022 14.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 OAJ25623.1 - 1.5e-06 28.5 0.0 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 OAJ25623.1 - 1.8e-06 27.6 0.1 0.016 14.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 OAJ25623.1 - 5.1e-06 26.0 0.3 0.96 8.7 0.0 3.4 3 0 0 3 3 3 2 KaiC Parvo_NS1 PF01057.17 OAJ25623.1 - 6.3e-06 25.5 0.2 0.0064 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ25623.1 - 8.3e-06 25.5 0.8 0.19 11.3 0.0 3.7 3 1 1 4 4 3 1 AAA domain AAA_28 PF13521.6 OAJ25623.1 - 9e-06 26.0 0.0 0.085 13.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 OAJ25623.1 - 1.3e-05 24.5 0.0 0.0032 16.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 OAJ25623.1 - 1.9e-05 25.2 0.0 0.14 12.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 OAJ25623.1 - 1.9e-05 24.4 0.0 0.36 10.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 OAJ25623.1 - 3.4e-05 23.7 0.2 0.18 11.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 OAJ25623.1 - 8e-05 23.1 0.1 0.91 9.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 OAJ25623.1 - 0.0001 21.8 0.2 0.41 10.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.18 OAJ25623.1 - 0.00011 22.2 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 OAJ25623.1 - 0.00017 21.6 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 OAJ25623.1 - 0.00018 21.6 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OAJ25623.1 - 0.00022 21.1 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ25623.1 - 0.00059 19.8 0.3 0.15 12.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 OAJ25623.1 - 0.00067 19.5 0.4 1.2 8.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 OAJ25623.1 - 0.00095 19.0 0.0 0.16 11.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OAJ25623.1 - 0.0012 18.2 0.0 1.3 8.2 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 OAJ25623.1 - 0.0015 18.2 0.7 1.5 8.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 OAJ25623.1 - 0.0022 18.1 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 OAJ25623.1 - 0.0022 18.0 0.1 3.1 7.6 0.0 3.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 OAJ25623.1 - 0.0023 18.3 1.7 2.3 8.6 0.0 3.7 3 1 1 4 4 3 1 AAA domain DUF2075 PF09848.9 OAJ25623.1 - 0.0047 16.2 1.8 1.2 8.3 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 OAJ25623.1 - 0.0066 15.7 0.0 0.6 9.3 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain UFD1 PF03152.14 OAJ25623.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.15 OAJ25623.1 - 0.018 15.0 0.4 2.6 8.0 0.0 3.4 3 0 0 3 3 3 0 NTPase IPT PF01745.16 OAJ25623.1 - 0.025 13.9 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 OAJ25623.1 - 0.036 13.8 0.3 4.7 6.9 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 OAJ25623.1 - 0.042 12.7 0.0 4.8 6.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Molydop_binding PF01568.21 OAJ25623.1 - 0.047 13.7 0.1 0.69 10.0 0.0 2.7 2 1 1 3 3 2 0 Molydopterin dinucleotide binding domain T2SSE PF00437.20 OAJ25623.1 - 0.054 12.5 0.0 0.87 8.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 OAJ25623.1 - 0.063 12.5 0.0 0.66 9.2 0.0 2.4 2 1 0 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.7 OAJ25623.1 - 0.23 10.4 0.1 8.5 5.2 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Hydin_ADK PF17213.3 OAJ25623.1 - 1.1 9.5 2.8 43 4.3 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Ribosomal_L2_C PF03947.18 OAJ25624.1 - 3.8e-46 156.4 3.0 5.3e-46 155.9 3.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAJ25624.1 - 0.0075 16.2 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain UPRTase PF14681.6 OAJ25625.1 - 1.2e-78 263.3 0.0 1.4e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAJ25625.1 - 0.0021 17.6 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain peroxidase PF00141.23 OAJ25626.1 - 2.2e-49 168.2 0.0 3.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Transposase_21 PF02992.14 OAJ25627.1 - 9.5e-07 28.3 0.0 2.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ25627.1 - 0.0013 18.3 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pyrophosphatase PF00719.19 OAJ25629.1 - 5.7e-60 201.7 0.2 7.2e-60 201.4 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Lactamase_B_3 PF13483.6 OAJ25630.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 Beta-lactamase superfamily domain ChaC PF04752.12 OAJ25631.1 - 4.1e-51 173.6 0.0 8.1e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.31 OAJ25631.1 - 3.5e-25 87.9 0.9 9.1e-25 86.6 0.9 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAJ25631.1 - 1.2e-08 35.0 1.2 3.2e-08 33.6 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ25631.1 - 4.4e-06 26.9 0.5 8e-06 26.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAJ25631.1 - 0.013 15.8 0.1 0.042 14.2 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TetR_C_30 PF17939.1 OAJ25631.1 - 0.047 13.9 0.3 0.71 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain APOBEC_C PF05240.14 OAJ25631.1 - 0.096 12.7 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain zf-C2H2 PF00096.26 OAJ25631.1 - 0.68 10.5 1.7 0.87 10.2 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type LOR PF04525.12 OAJ25632.1 - 3.2e-27 95.3 0.0 4.1e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related DUF4580 PF15162.6 OAJ25632.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) CCDC53 PF10152.9 OAJ25633.1 - 0.01 16.3 0.4 0.026 15.0 0.0 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HSP70 PF00012.20 OAJ25634.1 - 1.9e-06 26.4 0.0 2.3e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Ntox3 PF15536.6 OAJ25635.1 - 0.039 14.0 0.2 0.054 13.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial toxin 3 Zn_ribbon_17 PF17120.5 OAJ25635.1 - 0.039 13.6 7.7 0.09 12.4 7.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PH_10 PF15411.6 OAJ25636.1 - 2.2e-21 76.4 0.0 4.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 OAJ25636.1 - 2.5e-06 27.8 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OAJ25636.1 - 4.2e-05 23.5 0.0 0.001 19.0 0.0 2.7 1 1 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.29 OAJ25636.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 PH domain Pkinase PF00069.25 OAJ25638.1 - 8e-39 133.6 0.0 1.7e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25638.1 - 6e-10 38.8 0.0 9.4e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.10 OAJ25638.1 - 4.3e-09 35.4 0.0 2.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.23 OAJ25638.1 - 2.4e-05 24.4 0.0 9.1e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ25638.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OAJ25638.1 - 0.017 14.5 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF724 PF05266.14 OAJ25639.1 - 0.025 14.4 6.8 0.031 14.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MCRS_N PF13325.6 OAJ25639.1 - 0.059 13.4 3.4 0.071 13.1 3.4 1.1 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein THOC7 PF05615.13 OAJ25639.1 - 0.3 11.3 10.3 0.9 9.8 9.9 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 PFL-like PF02901.15 OAJ25639.1 - 0.38 9.3 7.1 0.47 9.0 7.1 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase-like D123 PF07065.14 OAJ25640.1 - 0.3 10.2 0.1 0.56 9.3 0.0 1.4 1 1 0 1 1 1 0 D123 SR-25 PF10500.9 OAJ25640.1 - 2.6 7.6 14.1 1.6 8.3 10.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DHO_dh PF01180.21 OAJ25641.1 - 1.8e-90 303.1 0.0 2.6e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OAJ25641.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 OAJ25641.1 - 0.0017 17.5 0.4 0.028 13.4 0.1 3.1 3 1 0 3 3 3 1 FMN-dependent dehydrogenase FA_hydroxylase PF04116.13 OAJ25642.1 - 6.4e-23 81.6 20.3 6.4e-23 81.6 20.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.19 OAJ25642.1 - 0.2 12.3 7.9 0.4 11.3 7.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Scs3p PF10261.9 OAJ25643.1 - 5e-49 167.0 0.0 1.4e-48 165.6 0.0 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM YsaB PF13983.6 OAJ25643.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 YsaB-like lipoprotein DUF938 PF06080.12 OAJ25644.1 - 4.3e-29 101.7 0.0 6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 OAJ25644.1 - 0.018 15.8 0.1 0.087 13.6 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ25644.1 - 0.026 15.2 0.0 7.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Med11 PF10280.9 OAJ25645.1 - 1.5e-08 35.2 1.2 2.7e-08 34.4 1.2 1.5 1 1 0 1 1 1 1 Mediator complex protein CwsA PF10814.8 OAJ25645.1 - 0.037 14.2 4.1 0.08 13.1 0.1 2.4 2 1 0 2 2 2 0 Cell wall synthesis protein CwsA CSTF_C PF14304.6 OAJ25645.1 - 0.13 11.9 0.3 0.24 11.0 0.3 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 OAJ25646.1 - 1e-34 118.2 0.0 6.5e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSN1_7TM PF02714.15 OAJ25647.1 - 2.4e-28 99.2 23.0 3.4e-28 98.7 23.0 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAJ25647.1 - 1.5e-15 57.3 2.6 1.5e-15 57.3 2.6 3.9 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAJ25647.1 - 8.1e-15 55.5 4.2 5.7e-10 39.7 0.1 3.5 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter AvrPto PF11592.8 OAJ25647.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto MULE PF10551.9 OAJ25648.1 - 1.2e-22 80.1 0.0 3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ25648.1 - 9.4e-06 24.7 0.2 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.15 OAJ25648.1 - 0.25 12.1 1.7 0.62 10.8 1.7 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain FlaG PF03646.15 OAJ25649.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 FlaG protein Pinin_SDK_memA PF04696.13 OAJ25650.1 - 9.5e-11 41.9 6.0 9.5e-11 41.9 6.0 3.6 3 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region DUF4407 PF14362.6 OAJ25650.1 - 0.55 9.5 18.1 0.83 9.0 11.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 OAJ25650.1 - 0.72 10.3 9.7 1 9.8 2.1 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Ecl1 PF12855.7 OAJ25654.1 - 0.0021 19.3 5.5 0.0021 19.3 5.5 11.3 6 4 1 8 8 8 1 ECL1/2/3 zinc binding proteins GMC_oxred_N PF00732.19 OAJ25655.1 - 4.5e-51 174.0 0.0 7.6e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ25655.1 - 3.5e-35 121.6 0.0 7.5e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAJ25655.1 - 0.00047 19.3 0.2 0.00088 18.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAJ25655.1 - 0.0016 17.6 0.0 0.052 12.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ25655.1 - 0.002 18.3 0.6 0.007 16.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ25655.1 - 0.0033 16.7 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAJ25655.1 - 0.15 12.3 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 OAJ25655.1 - 0.3 10.6 5.9 0.24 10.9 0.9 3.1 4 0 0 4 4 4 0 FAD dependent oxidoreductase Phage_Gp23 PF10669.9 OAJ25655.1 - 5.5 7.3 8.2 8.8 6.7 8.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Glyco_hydro_16 PF00722.21 OAJ25656.1 - 8.2e-33 113.3 0.8 2e-32 112.1 0.8 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MutL_C PF08676.11 OAJ25656.1 - 1.7e-07 31.1 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OAJ25656.1 - 0.0049 16.7 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ25656.1 - 0.017 15.6 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2985 PF11204.8 OAJ25657.1 - 2.3e-25 88.5 1.7 4.5e-25 87.6 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.6 OAJ25657.1 - 0.085 12.9 0.7 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Putative sensor NAD_binding_8 PF13450.6 OAJ25658.1 - 3e-08 33.8 0.0 8.5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ25658.1 - 7.1e-08 32.4 0.1 3.5e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ25658.1 - 1.6e-07 31.5 0.2 0.028 14.4 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ25658.1 - 1.5e-06 27.7 0.0 0.0063 15.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAJ25658.1 - 3.5e-06 25.7 0.0 0.15 10.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAJ25658.1 - 2.7e-05 23.5 0.0 0.0097 15.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAJ25658.1 - 0.00074 18.9 0.0 0.23 10.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAJ25658.1 - 0.001 19.2 0.0 0.7 9.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAJ25658.1 - 0.016 14.4 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OAJ25658.1 - 0.034 12.9 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 OAJ25658.1 - 0.044 12.9 0.1 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAJ25658.1 - 0.077 12.3 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAJ25658.1 - 0.078 12.0 0.0 9.7 5.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAJ25658.1 - 0.086 12.1 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CRAL_TRIO PF00650.20 OAJ25660.1 - 1.6e-34 119.0 0.0 2.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ25660.1 - 2.2e-10 40.6 0.2 7.6e-10 38.8 0.4 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain ThiS PF02597.20 OAJ25660.1 - 6.5e-08 33.1 0.1 5.6e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 ThiS family TFIIA PF03153.13 OAJ25660.1 - 0.091 12.7 27.6 0.12 12.3 16.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aa_trans PF01490.18 OAJ25661.1 - 1.5e-45 155.6 32.4 1.8e-45 155.4 32.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Allantoicase PF03561.15 OAJ25662.1 - 7.4e-85 282.2 0.0 2.8e-42 144.1 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 OAJ25662.1 - 6.4e-54 182.6 0.0 9.6e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase G6PD_C PF02781.16 OAJ25663.1 - 6.3e-107 357.1 0.0 8.5e-107 356.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAJ25663.1 - 1.8e-59 201.4 0.1 3.1e-59 200.6 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain LOR PF04525.12 OAJ25664.1 - 4.6e-18 65.5 0.0 5.6e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related DUF3137 PF11335.8 OAJ25665.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Uds1 PF15456.6 OAJ25666.1 - 6.9e-21 74.8 4.3 6.9e-21 74.8 4.3 14.1 5 2 6 11 11 11 1 Up-regulated During Septation DUF3786 PF12654.7 OAJ25666.1 - 1.8 8.1 4.9 3.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3786) Methyltransf_28 PF02636.17 OAJ25667.1 - 7.9e-64 215.8 0.0 1.2e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 OAJ25668.1 - 3.1e-72 243.1 0.0 3.9e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25668.1 - 3.7e-31 108.3 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ25668.1 - 2.7e-14 53.6 1.1 8e-14 52.1 1.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAJ25668.1 - 1.4e-06 27.5 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ25668.1 - 0.0002 20.8 0.0 0.00072 19.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAJ25668.1 - 0.0072 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ25668.1 - 0.0096 15.6 0.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAJ25668.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4028 PF13220.6 OAJ25669.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) SGS PF05002.15 OAJ25670.1 - 1.8e-29 101.7 1.6 3.6e-29 100.7 1.6 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OAJ25670.1 - 1.1e-09 39.2 0.0 1.9e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 CS domain ELP6 PF09807.9 OAJ25671.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 AAA_25 PF13481.6 OAJ25671.1 - 8.8e-06 25.4 0.1 1.3e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ25671.1 - 0.0088 16.0 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 NACHT domain DUF4990 PF16380.5 OAJ25671.1 - 0.074 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Aminotran_5 PF00266.19 OAJ25672.1 - 3.5e-29 101.9 0.0 5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 OAJ25672.1 - 4.1e-27 95.0 49.1 1.3e-26 93.4 48.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 OAJ25673.1 - 1.8e-13 50.4 13.4 2.7e-09 36.8 0.4 2.4 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ25673.1 - 6e-12 46.2 0.0 1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF4407 PF14362.6 OAJ25673.1 - 0.016 14.6 0.2 0.039 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_21 PF13304.6 OAJ25673.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system HCO3_cotransp PF00955.21 OAJ25678.1 - 4.3e-56 190.8 16.0 1.5e-27 96.6 7.3 3.1 2 1 0 3 3 3 3 HCO3- transporter family CbtB PF09489.10 OAJ25678.1 - 0.22 11.7 1.5 17 5.6 0.1 3.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) IU_nuc_hydro PF01156.19 OAJ25679.1 - 2.8e-78 263.6 0.0 3.3e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SRF-TF PF00319.18 OAJ25679.1 - 0.22 11.0 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Transposase_21 PF02992.14 OAJ25680.1 - 4.9e-08 32.5 0.1 1.2e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ25680.1 - 0.0054 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) NINJA_B PF16136.5 OAJ25681.1 - 0.0065 16.8 1.0 0.015 15.7 1.0 1.6 1 0 0 1 1 1 1 Putative nuclear localisation signal DUF3701 PF12482.8 OAJ25681.1 - 0.078 13.1 0.4 0.73 9.9 0.1 2.6 3 0 0 3 3 3 0 Phage integrase protein p450 PF00067.22 OAJ25682.1 - 2.1e-44 152.1 0.0 3e-44 151.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RHH_4 PF13467.6 OAJ25682.1 - 0.11 12.4 0.8 1.2 9.1 0.4 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain SAP130_C PF16014.5 OAJ25682.1 - 0.21 10.6 4.4 0.36 9.9 4.4 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Phasin_2 PF09361.10 OAJ25682.1 - 1.6 9.1 21.7 5.8 7.2 21.7 1.9 1 0 0 1 1 1 0 Phasin protein VHS PF00790.19 OAJ25683.1 - 6.9e-41 139.4 0.0 1.9e-40 138.0 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 OAJ25683.1 - 1.2e-18 67.1 0.4 3.8e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 OAJ25683.1 - 0.85 9.3 4.0 1.5 8.5 0.2 2.9 3 0 0 3 3 3 0 GGA N-GAT domain Med3 PF11593.8 OAJ25683.1 - 3.3 6.8 15.6 0.26 10.5 9.6 1.9 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal GCP_N_terminal PF17681.1 OAJ25684.1 - 4.3e-61 207.2 0.0 1.4e-28 100.5 0.1 3.4 3 0 0 3 3 3 3 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAJ25684.1 - 8.4e-43 147.0 4.2 1.7e-42 146.0 4.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal YL1 PF05764.13 OAJ25684.1 - 5e-05 23.5 9.1 5e-05 23.5 9.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Nop53 PF07767.11 OAJ25684.1 - 0.00094 18.7 12.7 0.00094 18.7 12.7 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Apt1 PF10351.9 OAJ25684.1 - 0.021 13.7 0.3 0.046 12.6 0.3 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rrn6 PF10214.9 OAJ25684.1 - 0.2 10.1 3.6 0.38 9.2 3.6 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 OAJ25684.1 - 0.21 9.8 18.9 0.37 9.0 18.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4484 PF14831.6 OAJ25684.1 - 0.23 11.5 8.0 9.9 6.1 6.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Pes-10 PF07149.11 OAJ25684.1 - 0.38 9.7 7.9 0.64 9.0 7.9 1.3 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 OAJ25684.1 - 0.48 9.8 15.2 0.96 8.8 15.2 1.4 1 0 0 1 1 1 0 SDA1 Nucleoporin_FG PF13634.6 OAJ25685.1 - 0.0075 17.1 36.3 0.0075 17.1 36.3 3.8 2 1 2 4 4 4 3 Nucleoporin FG repeat region PAT1 PF09770.9 OAJ25685.1 - 8 4.6 38.0 11 4.1 38.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 OAJ25685.1 - 9.3 6.0 13.1 18 5.0 13.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DcpS_C PF11969.8 OAJ25687.1 - 7.3e-21 74.8 0.7 1.5e-20 73.8 0.7 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ25687.1 - 1.5e-08 35.3 3.4 6.4e-08 33.2 3.4 1.8 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 OAJ25687.1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Chorion_3 PF05387.11 OAJ25688.1 - 0.35 10.5 2.5 0.53 9.9 2.5 1.2 1 0 0 1 1 1 0 Chorion family 3 KxDL PF10241.9 OAJ25688.1 - 1.6 9.1 8.1 0.83 10.0 2.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 OAJ25688.1 - 3.8 8.1 11.5 2.2 8.9 6.2 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal WD40 PF00400.32 OAJ25689.1 - 2.3e-18 66.2 3.9 0.00019 22.1 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ25689.1 - 5e-09 36.3 0.0 4.2e-05 23.8 0.0 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ25689.1 - 4.8e-05 23.3 0.0 0.011 15.6 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAJ25689.1 - 0.022 14.1 0.0 0.095 12.0 0.0 2.0 3 0 0 3 3 3 0 WD40-like domain Frag1 PF10277.9 OAJ25691.1 - 3.2e-38 131.5 14.9 3.7e-38 131.3 14.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Yip1 PF04893.17 OAJ25691.1 - 0.0063 16.2 4.5 0.0063 16.2 4.5 2.5 1 1 1 2 2 2 1 Yip1 domain Peptidase_M43 PF05572.13 OAJ25693.1 - 2.5e-16 59.9 0.4 5.1e-16 58.9 0.4 1.6 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 OAJ25693.1 - 0.00042 20.0 0.0 0.00095 18.9 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ25693.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 OAJ25693.1 - 0.005 17.4 0.3 0.066 13.7 0.3 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ25693.1 - 0.0064 16.7 0.1 0.012 15.8 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 OAJ25693.1 - 0.034 14.3 0.1 0.069 13.3 0.1 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family CCAP PF11105.8 OAJ25695.1 - 0.087 12.8 3.3 1.3 9.0 0.6 2.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Fer2_2 PF01799.20 OAJ25695.1 - 5.5 7.1 9.0 0.52 10.4 1.6 2.6 2 1 0 2 2 2 0 [2Fe-2S] binding domain PINIT PF14324.6 OAJ25696.1 - 3.6e-23 82.5 0.3 5.2e-23 82.0 0.3 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAJ25696.1 - 2.3e-21 75.3 4.0 3.6e-21 74.6 4.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAJ25696.1 - 1.9e-08 34.0 0.9 3.6e-08 33.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 OAJ25696.1 - 0.05 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 SAP domain zf-C3HC4_2 PF13923.6 OAJ25696.1 - 0.8 9.6 3.3 1.5 8.8 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3915 PF13054.6 OAJ25696.1 - 8.1 6.5 5.3 24 4.9 5.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) rRNA_proc-arch PF13234.6 OAJ25698.1 - 8.7e-75 252.1 0.5 1.3e-74 251.6 0.1 1.5 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 OAJ25698.1 - 8.7e-51 171.8 1.7 2.2e-50 170.5 1.7 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OAJ25698.1 - 1.6e-18 67.1 0.0 6.6e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ25698.1 - 1.3e-06 28.7 0.0 9.8e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PilJ PF13675.6 OAJ25701.1 - 0.025 14.6 0.7 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prefoldin PF02996.17 OAJ25701.1 - 0.029 14.3 2.8 0.044 13.7 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.15 OAJ25701.1 - 0.031 14.1 3.9 0.032 14.0 1.7 2.0 2 0 0 2 2 2 0 Septum formation initiator BRE1 PF08647.11 OAJ25701.1 - 0.077 13.1 1.7 0.29 11.2 1.7 2.0 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 OAJ25701.1 - 0.35 10.2 6.5 6.2 6.1 3.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlgN PF05130.12 OAJ25701.1 - 0.56 10.7 7.2 0.26 11.8 3.8 2.1 2 0 0 2 2 2 0 FlgN protein DUF4140 PF13600.6 OAJ25701.1 - 6.6 7.2 7.3 3.8 8.0 0.7 3.4 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Vps36_ESCRT-II PF11605.8 OAJ25702.1 - 3.3e-20 72.0 0.0 6.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 OAJ25702.1 - 4e-19 68.8 0.1 1.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 EAP30/Vps36 family Rubredoxin PF00301.20 OAJ25702.1 - 0.053 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin Vps36-NZF-N PF16988.5 OAJ25702.1 - 0.095 12.1 3.3 0.34 10.4 3.3 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 OAJ25702.1 - 0.27 10.6 1.7 0.5 9.7 1.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CTU2 PF10288.9 OAJ25702.1 - 0.36 11.1 5.2 0.33 11.2 2.2 2.4 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 CENP-B_dimeris PF09026.10 OAJ25702.1 - 0.97 9.9 4.9 2.4 8.6 4.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DEC-1_N PF04625.13 OAJ25703.1 - 0.012 14.7 12.6 0.012 14.6 12.6 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5525 PF17663.1 OAJ25703.1 - 0.29 9.1 16.2 0.3 9.1 16.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) HsbA PF12296.8 OAJ25704.1 - 9.8e-08 32.5 2.9 9.8e-08 32.5 2.9 2.0 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Vps51 PF08700.11 OAJ25704.1 - 0.11 12.6 0.3 2.6 8.2 0.0 2.3 1 1 1 2 2 2 0 Vps51/Vps67 CS PF04969.16 OAJ25705.1 - 7.4e-19 68.6 0.1 1.3e-18 67.7 0.1 1.4 1 0 0 1 1 1 1 CS domain CLU PF13236.6 OAJ25706.1 - 7.1e-69 232.0 0.0 1.3e-68 231.1 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAJ25706.1 - 5.7e-46 156.8 0.0 1.4e-45 155.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAJ25706.1 - 4.2e-21 75.0 14.7 7.5e-10 39.0 1.3 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ25706.1 - 7e-07 28.9 19.5 0.0052 16.6 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat CLU_N PF15044.6 OAJ25706.1 - 7e-06 26.3 0.1 5.5e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 OAJ25706.1 - 0.00018 21.1 0.2 0.0063 16.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ25706.1 - 0.078 13.8 5.3 0.33 11.9 0.0 4.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ25706.1 - 0.081 13.0 1.4 2.9 8.1 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ25706.1 - 5.7 7.3 10.8 0.96 9.7 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DASH_Dad1 PF08649.10 OAJ25707.1 - 2e-22 79.1 0.8 2.5e-22 78.8 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF5320 PF17253.2 OAJ25707.1 - 5.1 8.2 9.5 15 6.7 8.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Mito_carr PF00153.27 OAJ25711.1 - 1.6e-54 181.8 3.3 2.5e-18 65.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mitochondr_Som1 PF11093.8 OAJ25712.1 - 1.6e-09 37.6 0.3 2e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Dynamin_M PF01031.20 OAJ25713.1 - 3e-12 46.4 0.0 3.1e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region rOmpB PF12334.8 OAJ25713.1 - 0.07 12.6 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Dynamin_M PF01031.20 OAJ25714.1 - 3.7e-10 39.5 0.0 4.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region CorA PF01544.18 OAJ25715.1 - 6.5e-19 68.3 3.7 7e-11 42.0 0.2 3.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2705 PF10920.8 OAJ25715.1 - 0.075 12.3 0.6 0.12 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) GvpL_GvpF PF06386.11 OAJ25715.1 - 0.13 12.1 4.6 0.46 10.4 4.6 1.9 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3605 PF12239.8 OAJ25716.1 - 4.2e-24 85.6 0.8 7.5e-19 68.6 0.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) SPX PF03105.19 OAJ25716.1 - 0.11 12.4 4.6 0.13 12.2 4.6 1.2 1 0 0 1 1 1 0 SPX domain SUZ PF12752.7 OAJ25716.1 - 0.2 12.4 4.9 0.82 10.5 4.9 2.1 1 1 0 1 1 1 0 SUZ domain MAP65_ASE1 PF03999.12 OAJ25716.1 - 0.22 10.2 2.2 0.3 9.7 2.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Bromodomain PF00439.25 OAJ25717.1 - 1.4e-20 73.1 0.2 2.7e-20 72.2 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAJ25717.1 - 8.5e-07 28.9 0.2 3.8e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Bromodomain associated Efg1 PF10153.9 OAJ25718.1 - 9.1e-20 71.1 5.1 2.3e-19 69.9 5.1 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 NOA36 PF06524.12 OAJ25718.1 - 1.6 8.0 8.2 3.4 6.9 8.2 1.5 1 0 0 1 1 1 0 NOA36 protein CCDC-167 PF15188.6 OAJ25718.1 - 3 8.2 5.7 2.7 8.4 0.9 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Rad60-SLD_2 PF13881.6 OAJ25719.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mucin PF01456.17 OAJ25719.1 - 2.1 8.3 8.7 3.6 7.6 8.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dynamin_N PF00350.23 OAJ25720.1 - 1e-23 84.2 0.0 1.4e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAJ25720.1 - 1.8e-19 70.0 0.0 2.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region zf-C2H2_jaz PF12171.8 OAJ25721.1 - 2.7e-07 30.7 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ25721.1 - 4.5e-05 23.7 0.2 7.2e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 OAJ25721.1 - 0.00016 21.7 0.1 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 OAJ25721.1 - 0.062 14.2 0.1 0.12 13.3 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2203 PF09969.9 OAJ25721.1 - 0.21 12.3 4.4 0.37 11.5 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phosducin PF02114.16 OAJ25722.1 - 7.8e-15 54.5 0.2 8.3e-07 28.2 0.0 3.3 3 0 0 3 3 3 3 Phosducin PA_decarbox PF05870.11 OAJ25723.1 - 1.7e-25 89.5 0.7 1.9e-25 89.3 0.7 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF_C PF17409.2 OAJ25723.1 - 5.6e-08 32.4 0.7 7.8e-08 32.0 0.7 1.3 1 0 0 1 1 1 1 MoaF C-terminal domain MoaF PF10703.9 OAJ25723.1 - 0.0005 20.0 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 MoaF N-terminal domain 2-Hacid_dh_C PF02826.19 OAJ25724.1 - 4.6e-36 123.9 0.0 4.3e-35 120.7 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ25724.1 - 0.00039 20.5 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh PF00389.30 OAJ25724.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Rhomboid PF01694.22 OAJ25726.1 - 5.5e-11 42.7 11.7 6.9e-05 22.9 6.3 2.6 2 1 0 2 2 2 2 Rhomboid family PIG-L PF02585.17 OAJ25728.1 - 7.5e-25 88.1 0.4 1e-24 87.6 0.4 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_20 PF00728.22 OAJ25729.1 - 2.6e-81 273.8 0.0 3.3e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAJ25729.1 - 5.4e-15 56.3 0.0 8.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAJ25729.1 - 0.0019 18.9 0.4 0.046 14.5 0.4 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PPP4R2 PF09184.11 OAJ25730.1 - 0.012 15.2 4.5 0.018 14.7 4.5 1.3 1 0 0 1 1 1 0 PPP4R2 DUF3246 PF11596.8 OAJ25730.1 - 0.022 14.2 0.4 0.044 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NOA36 PF06524.12 OAJ25730.1 - 0.1 11.9 5.0 0.16 11.3 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ25730.1 - 0.55 9.9 8.9 0.81 9.4 8.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIE-A_C PF11521.8 OAJ25730.1 - 1.6 9.0 7.8 10 6.5 0.6 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF2456 PF10445.9 OAJ25731.1 - 7.6e-18 64.4 1.9 7.6e-18 64.4 1.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) GGACT PF06094.12 OAJ25733.1 - 2.4e-10 41.1 0.0 4.9e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ArfGap PF01412.18 OAJ25734.1 - 2e-32 111.7 0.7 3.8e-32 110.8 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf ERM PF00769.19 OAJ25734.1 - 8.7 6.1 17.6 14 5.4 17.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Lon_C PF05362.13 OAJ25736.1 - 1e-64 217.9 0.1 1.8e-64 217.1 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 OAJ25736.1 - 1.3e-22 80.6 0.0 3.3e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ25736.1 - 1.5e-09 38.0 0.0 1.1e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAJ25736.1 - 4.4e-08 33.0 0.0 9.1e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON_substr_bdg PF02190.16 OAJ25736.1 - 4.9e-07 29.8 0.0 1.6e-06 28.2 0.0 1.8 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_16 PF13191.6 OAJ25736.1 - 3.7e-05 24.2 0.1 3.7e-05 24.2 0.1 2.8 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ25736.1 - 0.00056 20.2 0.2 0.013 15.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ25736.1 - 0.00077 19.6 0.0 0.0036 17.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ25736.1 - 0.0035 17.5 0.4 0.034 14.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ25736.1 - 0.0074 16.0 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ25736.1 - 0.018 14.4 0.0 0.051 13.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAJ25736.1 - 0.019 15.5 0.0 0.061 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ25736.1 - 0.027 14.9 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OAJ25736.1 - 0.033 13.9 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 OAJ25736.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 OAJ25736.1 - 0.042 12.8 0.0 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain TniB PF05621.11 OAJ25736.1 - 0.049 13.0 0.3 5.4 6.4 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein AAA_25 PF13481.6 OAJ25736.1 - 0.071 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cut8 PF08559.10 OAJ25736.1 - 0.085 12.5 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein NACHT PF05729.12 OAJ25736.1 - 0.087 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TelA PF05816.11 OAJ25736.1 - 0.15 11.1 0.8 0.29 10.1 0.8 1.4 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA_7 PF12775.7 OAJ25736.1 - 0.17 11.4 0.0 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAJ25736.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain GREB1 PF15782.5 OAJ25736.1 - 0.2 8.7 0.0 0.28 8.2 0.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer KTI12 PF08433.10 OAJ25736.1 - 0.2 11.1 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 OAJ25736.1 - 0.88 10.0 0.0 0.88 10.0 0.0 2.7 2 1 1 3 3 2 0 AAA domain Aminotran_5 PF00266.19 OAJ25737.1 - 6.4e-16 58.3 0.0 2.7e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ25737.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II SDA1 PF05285.12 OAJ25738.1 - 0.1 12.0 8.0 0.1 12.0 8.0 1.2 1 0 0 1 1 1 0 SDA1 GP67 PF17634.2 OAJ25738.1 - 0.15 12.5 16.7 0.26 11.7 16.7 1.3 1 0 0 1 1 1 0 Gene product 67 HA2 PF04408.23 OAJ25738.1 - 0.34 11.2 2.7 0.62 10.4 2.7 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) FAM176 PF14851.6 OAJ25738.1 - 0.49 10.1 3.8 0.86 9.3 3.8 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 OAJ25738.1 - 0.97 9.4 6.8 1.4 8.9 6.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal BIRC6 PF12356.8 OAJ25738.1 - 2 7.8 6.2 3.4 7.1 6.2 1.3 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Sporozoite_P67 PF05642.11 OAJ25738.1 - 2.8 5.9 8.2 3.4 5.6 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SGT1 PF07093.11 OAJ25738.1 - 3.5 5.9 8.3 4.6 5.6 8.3 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 OAJ25738.1 - 4.2 5.5 11.6 5.5 5.1 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ25738.1 - 4.4 5.5 9.6 5.6 5.1 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 OAJ25738.1 - 6.6 5.9 6.5 8.8 5.4 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 OAJ25738.1 - 8.4 5.6 19.5 12 5.1 19.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 OAJ25738.1 - 9 5.3 18.4 14 4.7 18.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 OAJ25739.1 - 1.1e-39 136.4 0.1 2.6e-21 76.2 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25739.1 - 2.1e-11 43.6 0.7 1.7e-08 34.1 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase p450 PF00067.22 OAJ25740.1 - 1.9e-71 241.2 0.0 7e-44 150.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 tRNA-synt_1 PF00133.22 OAJ25741.1 - 2.7e-51 174.5 0.4 3.1e-51 174.4 0.4 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAJ25741.1 - 2.2e-05 23.4 0.1 2.9e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) RVT_1 PF00078.27 OAJ25742.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAJ25742.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAJ25742.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.22 OAJ25743.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAJ25743.1 - 0.0073 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 OAJ25743.1 - 0.034 14.6 0.0 0.071 13.6 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3440 PF11922.8 OAJ25743.1 - 0.086 12.5 0.0 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Ammonium_transp PF00909.21 OAJ25749.1 - 2.7e-104 349.1 29.3 3.4e-104 348.7 29.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YCII PF03795.14 OAJ25750.1 - 0.0073 16.7 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 YCII-related domain Serglycin PF04360.12 OAJ25750.1 - 0.04 13.8 18.9 2.1 8.3 15.8 2.8 3 0 0 3 3 3 0 Serglycin DUF1180 PF06679.12 OAJ25750.1 - 3.9 7.8 15.5 7.7 6.9 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ER_lumen_recept PF00810.18 OAJ25751.1 - 2e-49 168.2 3.9 2e-49 168.2 3.9 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAJ25751.1 - 0.0096 15.7 13.1 0.013 15.2 0.8 4.0 4 0 0 4 4 4 2 PQ loop repeat 40S_S4_C PF16121.5 OAJ25751.1 - 0.045 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus Mago_nashi PF02792.14 OAJ25752.1 - 8.5e-76 252.9 0.4 9.4e-76 252.7 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein ANAPC4 PF12896.7 OAJ25753.1 - 1.7e-21 76.6 0.1 2.8e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Nup_retrotrp_bd PF10599.9 OAJ25753.1 - 1.9 9.2 8.3 0.2 12.3 1.7 2.8 2 0 0 2 2 2 0 Retro-transposon transporting motif Mac PF12464.8 OAJ25754.1 - 5.9e-10 39.2 0.0 1.7e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 OAJ25754.1 - 1.9e-09 36.9 10.7 2.4e-07 30.2 7.2 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ25754.1 - 6.8e-07 28.9 8.7 2.7e-06 27.0 7.3 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase GMC_oxred_N PF00732.19 OAJ25756.1 - 8.3e-40 137.0 0.0 1.3e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ25756.1 - 4.6e-22 79.1 0.4 3.2e-20 73.1 0.4 3.0 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ25756.1 - 1.5e-08 34.1 1.2 3.7e-05 23.0 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ25756.1 - 2e-05 24.7 0.6 6.5e-05 23.1 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAJ25756.1 - 0.00034 20.0 0.1 0.00051 19.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAJ25756.1 - 0.00037 20.2 1.7 0.011 15.4 0.6 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ25756.1 - 0.0038 16.5 0.2 0.011 15.0 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ25756.1 - 0.014 14.8 1.0 0.021 14.2 1.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ25756.1 - 0.03 13.0 0.3 0.056 12.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAJ25756.1 - 0.042 13.1 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ25756.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAJ25756.1 - 0.18 10.9 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 OAJ25756.1 - 0.19 11.4 1.2 0.33 10.6 1.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.32 OAJ25757.1 - 2.5e-43 145.2 23.5 6.3e-08 33.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ25757.1 - 3.8e-11 43.1 0.1 0.023 15.0 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ25757.1 - 6.8e-07 28.3 5.1 0.11 11.1 0.2 4.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 OAJ25757.1 - 0.0092 15.1 0.0 0.64 9.1 0.0 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 OAJ25757.1 - 0.026 13.5 0.1 29 3.5 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OAJ25757.1 - 0.098 11.2 0.0 3.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 OAJ25757.1 - 0.18 11.1 0.0 23 4.2 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 OAJ25757.1 - 0.44 10.5 7.9 22 5.1 0.0 5.3 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat DUF1764 PF08576.10 OAJ25759.1 - 9.7e-22 77.8 22.4 1.2e-15 58.3 22.4 2.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) SRP-alpha_N PF04086.13 OAJ25759.1 - 0.91 9.4 19.5 1.2 9.0 19.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LCD1 PF09798.9 OAJ25759.1 - 2.5 6.5 5.8 2.6 6.5 5.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SOG2 PF10428.9 OAJ25759.1 - 3.5 6.7 14.7 4.4 6.4 14.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 OAJ25759.1 - 5.1 6.2 6.0 5.6 6.1 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 OAJ25759.1 - 5.5 5.4 10.3 6 5.3 10.3 1.0 1 0 0 1 1 1 0 Macoilin family FAM220 PF15487.6 OAJ25759.1 - 6.3 6.3 12.3 7.9 6.0 12.3 1.2 1 0 0 1 1 1 0 FAM220 family DUF4551 PF15087.6 OAJ25759.1 - 6.6 5.4 12.3 7.4 5.3 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 OAJ25759.1 - 8.7 5.0 12.5 11 4.6 12.5 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAJ25759.1 - 8.8 6.1 13.9 12 5.7 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HA2 PF04408.23 OAJ25760.1 - 5.2e-14 52.4 1.2 3.2e-13 49.9 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAJ25760.1 - 1.7e-13 50.9 0.0 3.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 OAJ25760.1 - 4e-08 33.8 4.1 0.00077 20.1 0.1 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 OAJ25760.1 - 5.5e-07 29.9 0.1 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OAJ25760.1 - 4.2e-05 23.4 0.0 8.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sde2_N_Ubi PF13019.6 OAJ25760.1 - 0.073 12.9 0.6 0.19 11.6 0.6 1.7 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Spt20 PF12090.8 OAJ25760.1 - 5.7 6.5 14.2 14 5.2 14.2 1.6 1 0 0 1 1 1 0 Spt20 family bZIP_1 PF00170.21 OAJ25761.1 - 4.7e-07 29.8 3.6 1e-06 28.7 3.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ25761.1 - 0.0026 17.8 3.9 0.006 16.6 3.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Alginate_lyase PF05426.12 OAJ25762.1 - 3e-49 168.0 6.0 3.6e-48 164.5 1.7 2.3 2 0 0 2 2 2 2 Alginate lyase JmjC PF02373.22 OAJ25763.1 - 1.6e-38 131.6 0.5 2.9e-38 130.8 0.5 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ25763.1 - 4.2e-13 49.0 0.9 8.2e-13 48.1 0.9 1.5 1 0 0 1 1 1 1 jmjN domain DUF5082 PF16888.5 OAJ25763.1 - 0.16 12.3 2.3 0.29 11.4 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 OAJ25763.1 - 2.4 8.2 15.5 1.7 8.7 7.1 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF155 PF02582.14 OAJ25764.1 - 2.3e-33 115.7 0.1 5.3e-31 108.1 0.0 3.0 2 1 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Maf1 PF09174.10 OAJ25764.1 - 0.28 11.3 3.0 0.79 9.9 3.0 1.7 1 0 0 1 1 1 0 Maf1 regulator SMYLE_N PF18615.1 OAJ25764.1 - 1.8 8.0 8.6 3.7 7.0 8.6 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CDK5_activator PF03261.15 OAJ25764.1 - 2.2 7.7 7.7 3.6 7.0 7.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein ASD2 PF08687.11 OAJ25764.1 - 2.7 7.5 14.4 27 4.2 0.0 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Bul1_N PF04425.12 OAJ25764.1 - 5 5.8 11.0 7.9 5.1 11.0 1.2 1 0 0 1 1 1 0 Bul1 N terminus FAM60A PF15396.6 OAJ25764.1 - 7.5 6.5 8.5 17 5.3 8.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 OAJ25764.1 - 9.2 4.9 14.8 16 4.1 14.8 1.3 1 0 0 1 1 1 0 Presenilin NST1 PF13945.6 OAJ25764.1 - 9.4 6.3 15.3 26 4.8 15.3 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator UTP15_C PF09384.10 OAJ25765.1 - 7.1e-35 119.8 0.0 1.4e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAJ25765.1 - 4e-23 81.2 0.8 4.7e-06 27.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAJ25765.1 - 0.0088 15.0 0.0 3.1 6.7 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MutL PF13941.6 OAJ25765.1 - 0.08 11.5 1.7 0.12 11.0 1.7 1.1 1 0 0 1 1 1 0 MutL protein Nup160 PF11715.8 OAJ25765.1 - 0.088 11.4 0.3 0.79 8.3 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 G_glu_transpept PF01019.21 OAJ25766.1 - 1.5e-136 456.2 0.0 1.8e-136 455.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ANTH PF07651.16 OAJ25767.1 - 3.1e-70 236.3 0.2 3.1e-70 236.3 0.2 2.6 2 1 2 4 4 4 1 ANTH domain I_LWEQ PF01608.17 OAJ25767.1 - 3.3e-56 189.8 11.1 3.3e-56 189.8 11.1 5.4 5 1 1 6 6 6 2 I/LWEQ domain ENTH PF01417.20 OAJ25767.1 - 0.00012 22.1 3.0 0.00067 19.7 0.0 3.7 3 1 1 4 4 4 1 ENTH domain ETF PF01012.21 OAJ25770.1 - 8.1e-44 149.7 9.5 1.4e-43 148.9 9.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAJ25770.1 - 6.2e-33 112.7 0.6 6.2e-33 112.7 0.6 2.2 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain BMC PF00936.19 OAJ25770.1 - 0.0065 16.4 1.6 0.0065 16.4 1.6 2.6 2 0 0 2 2 2 1 BMC domain CRAL_TRIO PF00650.20 OAJ25771.1 - 1.4e-23 83.3 0.0 1.9e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ25771.1 - 1.3e-05 25.2 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Miga PF10265.9 OAJ25771.1 - 0.075 12.0 0.6 0.091 11.7 0.6 1.1 1 0 0 1 1 1 0 Mitoguardin INCENP_ARK-bind PF03941.15 OAJ25771.1 - 0.2 11.6 1.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region RNase_P_p30 PF01876.16 OAJ25772.1 - 5.2e-40 137.2 0.1 1.2e-37 129.5 0.0 3.0 3 0 0 3 3 3 1 RNase P subunit p30 CCDC117 PF15810.5 OAJ25772.1 - 0.31 11.3 4.0 0.56 10.5 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 SUIM_assoc PF16619.5 OAJ25772.1 - 2.1 8.5 22.9 0.43 10.7 13.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EMP24_GP25L PF01105.24 OAJ25773.1 - 6.1e-40 137.1 0.1 7.1e-40 136.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LysM PF01476.20 OAJ25774.1 - 2.5e-10 40.2 0.0 0.0001 22.3 0.0 2.6 2 0 0 2 2 2 2 LysM domain Cytochrom_C PF00034.21 OAJ25775.1 - 4.9e-11 43.6 0.0 6.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAJ25775.1 - 1.8e-07 31.4 2.1 1.8e-06 28.2 2.1 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAJ25775.1 - 0.0025 17.5 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 OAJ25775.1 - 0.085 13.5 0.0 0.091 13.4 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 OAJ25775.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 eRF1_2 PF03464.15 OAJ25776.1 - 6.6e-44 149.5 0.0 1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAJ25776.1 - 3.6e-37 127.3 0.1 7.1e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAJ25776.1 - 2.7e-18 66.2 0.0 4.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 OAJ25776.1 - 1.1e-10 41.9 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OAJ25776.1 - 1.2e-08 35.3 0.0 2.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3600 PF12207.8 OAJ25776.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) DUF3440 PF11922.8 OAJ25776.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) EOS1 PF12326.8 OAJ25777.1 - 1.3e-46 158.8 0.0 3.7e-45 154.0 0.0 3.2 2 2 0 2 2 2 1 N-glycosylation protein SUIM_assoc PF16619.5 OAJ25777.1 - 0.0065 16.5 1.1 0.0065 16.5 1.1 5.6 4 1 1 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 ARL6IP6 PF15062.6 OAJ25777.1 - 8 6.7 7.9 3.7 7.7 0.8 2.8 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Tristanin_u2 PF16638.5 OAJ25778.1 - 0.0092 16.8 0.9 0.028 15.3 0.9 1.7 1 0 0 1 1 1 1 Unstructured region on methyltransferase between zinc-fingers GTSE1_N PF15259.6 OAJ25778.1 - 2 8.6 4.6 0.34 11.1 0.4 1.8 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 FoP_duplication PF13865.6 OAJ25778.1 - 2.3 8.8 8.6 4.6 7.9 8.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ion_trans PF00520.31 OAJ25782.1 - 1.4e-127 424.0 86.6 1.1e-39 136.2 11.8 5.1 5 0 0 5 5 5 5 Ion transport protein EF-hand_1 PF00036.32 OAJ25782.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OAJ25782.1 - 0.064 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain GPHH PF16905.5 OAJ25782.1 - 0.073 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated ANAPC4_WD40 PF12894.7 OAJ25783.1 - 0.00081 19.6 0.0 0.42 10.9 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ25783.1 - 0.0022 18.8 0.1 0.34 11.9 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Methyltransf_12 PF08242.12 OAJ25784.1 - 8.7e-07 29.6 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ25784.1 - 8.8e-06 26.3 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ25784.1 - 1.8e-05 25.3 0.0 3.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ25784.1 - 8.2e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Synaptobrevin PF00957.21 OAJ25785.1 - 2.5e-14 52.8 1.3 2.5e-14 52.8 1.3 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 OAJ25785.1 - 9.5e-11 41.6 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ysc84 PF04366.12 OAJ25786.1 - 2.3e-41 140.5 0.0 6.2e-41 139.1 0.0 1.8 1 0 0 1 1 1 1 Las17-binding protein actin regulator ANAPC_CDC26 PF10471.9 OAJ25786.1 - 1.9 9.4 13.4 0.7 10.8 1.5 3.9 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 SH3BGR PF04908.15 OAJ25787.1 - 4.2e-16 58.9 0.0 5.4e-08 32.9 0.0 3.2 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 OAJ25787.1 - 0.5 10.6 1.5 33 4.8 0.0 3.6 4 0 0 4 4 4 0 Glutaredoxin HSP70 PF00012.20 OAJ25788.1 - 6.4e-259 860.2 8.6 7.3e-259 860.0 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ25788.1 - 8e-16 57.8 0.5 1.6e-14 53.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OAJ25788.1 - 0.0075 16.7 2.1 2.6 8.5 0.0 3.2 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OAJ25788.1 - 0.015 14.6 0.2 0.038 13.3 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 OAJ25788.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MutS_III PF05192.18 OAJ25788.1 - 0.3 11.3 3.3 10 6.3 1.6 2.3 2 0 0 2 2 2 0 MutS domain III SMN PF06003.12 OAJ25789.1 - 3.9 6.7 8.2 4.7 6.4 8.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zinc_ribbon_15 PF17032.5 OAJ25790.1 - 1.7e-05 25.4 0.3 2.7e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 zinc-ribbon family FYVE_2 PF02318.16 OAJ25790.1 - 0.043 14.0 2.5 0.6 10.3 0.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger SIR2 PF02146.17 OAJ25791.1 - 4.3e-54 183.1 0.0 6.6e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family NepR PF18557.1 OAJ25791.1 - 0.27 10.9 1.1 0.62 9.8 1.1 1.6 1 0 0 1 1 1 0 Anti-sigma factor NepR MRP-S31 PF15433.6 OAJ25793.1 - 0.062 13.0 9.9 0.072 12.8 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Retinal PF15449.6 OAJ25793.1 - 0.3 8.8 32.5 0.36 8.6 32.5 1.0 1 0 0 1 1 1 0 Retinal protein GET2 PF08690.10 OAJ25793.1 - 0.34 10.5 15.9 0.41 10.3 15.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Neur_chan_memb PF02932.16 OAJ25793.1 - 1.9 8.5 8.0 2.4 8.2 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCSAP PF15748.5 OAJ25793.1 - 4.3 7.4 18.8 5.6 7.1 18.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 OAJ25793.1 - 5.5 5.7 13.6 6.2 5.5 13.6 1.2 1 0 0 1 1 1 0 Presenilin DUF1631 PF07793.11 OAJ25793.1 - 7 4.9 26.5 8.1 4.7 26.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) TFIIA PF03153.13 OAJ25793.1 - 8.8 6.2 33.2 11 5.9 33.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 OAJ25793.1 - 9.5 4.2 14.5 10 4.1 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Kinesin PF00225.23 OAJ25794.1 - 4.7e-98 328.2 5.2 5.3e-53 180.1 0.0 4.1 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 OAJ25794.1 - 2e-22 79.7 0.1 3.7e-20 72.4 0.0 3.7 3 0 0 3 3 3 1 Microtubule binding Macoilin PF09726.9 OAJ25794.1 - 0.00021 20.0 5.6 0.00021 20.0 5.6 6.9 3 2 2 6 6 6 1 Macoilin family Spc7 PF08317.11 OAJ25794.1 - 0.00027 19.9 10.5 0.00027 19.9 10.5 11.9 5 2 6 12 12 12 4 Spc7 kinetochore protein Methyltransf_16 PF10294.9 OAJ25795.1 - 0.00021 21.1 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 OAJ25795.1 - 0.0061 17.3 0.1 0.47 11.2 0.0 3.1 2 1 1 3 3 3 1 Methyltransferase domain LRS4 PF10422.9 OAJ25795.1 - 0.45 10.1 3.1 1 8.9 3.1 1.6 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ECH_1 PF00378.20 OAJ25797.1 - 3e-17 62.8 0.0 7.5e-17 61.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ25797.1 - 4.1e-07 29.8 0.0 9.3e-07 28.6 0.0 1.5 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Rhodanese PF00581.20 OAJ25799.1 - 3.4e-06 27.5 0.0 4.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_16 PF10294.9 OAJ25800.1 - 5.5e-18 65.3 0.0 1.7e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OAJ25800.1 - 0.00034 21.3 0.0 0.00079 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ25800.1 - 0.0053 17.5 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ25800.1 - 0.051 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 OAJ25801.1 - 4e-66 223.1 0.0 5e-34 117.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25801.1 - 2.8e-30 105.5 0.0 8.8e-15 54.7 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 OAJ25801.1 - 5e-19 68.8 4.6 6.4e-18 65.2 0.0 3.2 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs RWD PF05773.22 OAJ25801.1 - 4.7e-18 65.6 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 OAJ25801.1 - 4.3e-13 49.2 1.0 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 OAJ25801.1 - 7e-06 26.1 0.0 7e-06 26.1 0.0 3.6 4 2 0 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ25801.1 - 0.0017 17.8 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OAJ25801.1 - 0.0017 18.0 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OAJ25801.1 - 0.038 12.8 0.0 0.038 12.8 0.0 1.8 2 1 0 2 2 2 0 Fungal protein kinase BRF1 PF07741.13 OAJ25801.1 - 0.42 11.0 3.0 1.6 9.2 3.0 2.0 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CHD5 PF04420.14 OAJ25802.1 - 1e-47 161.9 0.0 1.2e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 CHD5-like protein Myosin_tail_1 PF01576.19 OAJ25802.1 - 0.074 10.9 0.1 0.094 10.5 0.1 1.0 1 0 0 1 1 1 0 Myosin tail TB2_DP1_HVA22 PF03134.19 OAJ25803.1 - 3.1e-20 71.9 9.2 3.2e-20 71.8 5.2 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family CTD_bind PF04818.13 OAJ25806.1 - 0.011 16.6 0.0 0.024 15.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 OAJ25806.1 - 0.07 13.6 1.2 0.45 11.0 0.5 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 OAJ25806.1 - 3.8 7.2 11.1 3.7 7.2 5.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Ribosomal_L6 PF00347.23 OAJ25807.1 - 2.2e-23 82.7 3.5 3.5e-11 43.6 0.3 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Cupin_5 PF06172.11 OAJ25808.1 - 5.8e-30 104.3 0.0 3.8e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) GATA PF00320.27 OAJ25809.1 - 4.9e-14 51.6 8.6 1.1e-13 50.5 8.6 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAJ25809.1 - 0.0079 15.7 1.6 0.015 14.8 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Auto_anti-p27 PF06677.12 OAJ25809.1 - 0.24 11.6 0.5 0.42 10.8 0.5 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ion_trans_2 PF07885.16 OAJ25819.1 - 8.8e-32 108.9 26.7 4.5e-16 58.6 10.8 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 OAJ25819.1 - 0.00017 20.9 15.6 0.038 13.2 4.7 2.5 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 OAJ25819.1 - 0.068 13.0 7.5 1.8 8.4 1.6 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel DUF2207 PF09972.9 OAJ25819.1 - 0.22 10.3 0.0 0.22 10.3 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4618 PF15397.6 OAJ25819.1 - 3.7 6.9 6.1 3.3 7.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) zf-C3HC4 PF00097.25 OAJ25820.1 - 3.8e-06 26.7 2.3 2.3e-05 24.2 0.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ25820.1 - 0.00029 20.8 1.0 0.00081 19.4 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Torus PF16131.5 OAJ25820.1 - 0.00045 20.9 4.7 0.0023 18.6 0.1 2.8 2 1 0 2 2 2 1 Torus domain zf-RING_2 PF13639.6 OAJ25820.1 - 0.00074 19.8 0.6 0.00074 19.8 0.6 3.4 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ25820.1 - 0.0042 16.9 4.6 0.0065 16.3 0.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ25820.1 - 0.016 15.1 2.2 0.13 12.3 0.5 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ25820.1 - 0.039 13.8 7.0 0.072 13.0 0.5 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 OAJ25820.1 - 0.079 13.5 14.9 1.1 9.8 7.1 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 OAJ25820.1 - 0.15 12.3 3.1 1.7 9.0 0.3 2.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAJ25820.1 - 0.27 11.1 7.5 0.54 10.2 1.1 2.7 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAJ25820.1 - 0.53 10.1 5.2 0.37 10.6 3.0 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-CCCH_4 PF18044.1 OAJ25820.1 - 0.74 9.7 13.4 0.3 11.0 5.7 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ25820.1 - 0.83 9.8 21.2 0.091 12.8 5.7 2.8 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH PF00642.24 OAJ25820.1 - 4.8 7.2 10.7 23 5.0 5.5 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Isy1 PF06246.12 OAJ25821.1 - 3.6e-80 269.2 6.6 4.9e-79 265.5 6.6 1.9 1 1 0 1 1 1 1 Isy1-like splicing family ADPrib_exo_Tox PF03496.14 OAJ25821.1 - 0.11 11.8 0.4 1 8.7 0.4 2.1 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Ribosomal_L37 PF08561.10 OAJ25824.1 - 1.4e-25 90.1 3.9 1.4e-25 90.1 3.9 3.1 2 2 0 2 2 2 1 Mitochondrial ribosomal protein L37 PPP1R35_C PF15503.6 OAJ25824.1 - 0.03 14.1 5.1 0.087 12.6 5.1 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Peptidase_S8 PF00082.22 OAJ25825.1 - 1.1e-56 192.3 1.7 1.8e-56 191.6 1.7 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 OAJ25825.1 - 4.8e-40 137.1 0.0 7.3e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Actin PF00022.19 OAJ25826.1 - 7.9e-94 314.6 0.0 9.7e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Actin Synaptobrevin PF00957.21 OAJ25827.1 - 1.4e-32 111.3 1.8 1.6e-32 111.2 1.8 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF948 PF06103.11 OAJ25827.1 - 1.5 9.1 5.9 0.87 9.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Chitin_synth_1 PF01644.17 OAJ25828.1 - 5.8e-80 267.0 0.1 8.2e-80 266.5 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ25828.1 - 4.9e-29 100.1 0.1 1e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ25828.1 - 6.4e-22 77.9 6.0 5.4e-20 71.5 0.1 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ25828.1 - 1.6e-07 31.5 0.2 1.6e-07 31.5 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF3778 PF12620.8 OAJ25829.1 - 0.093 12.3 1.3 1.1 8.9 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3778) SPX PF03105.19 OAJ25830.1 - 0.4 10.5 5.6 0.32 10.9 3.0 1.9 2 0 0 2 2 2 0 SPX domain Ribosomal_L30 PF00327.20 OAJ25831.1 - 4.8e-09 36.0 0.1 6.8e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MOZ_SAS PF01853.18 OAJ25832.1 - 4e-56 189.5 0.1 8.2e-56 188.5 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ25832.1 - 2.6e-13 49.3 5.7 8.8e-07 28.4 0.2 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain SUIM_assoc PF16619.5 OAJ25832.1 - 0.005 16.9 3.0 0.015 15.3 3.0 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Acetyltransf_7 PF13508.7 OAJ25832.1 - 0.038 14.4 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5525 PF17663.1 OAJ25832.1 - 1.5 6.8 13.5 2 6.4 13.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Gemini_C4 PF01492.17 OAJ25832.1 - 1.5 8.7 3.8 0.65 9.9 0.9 1.8 2 0 0 2 2 2 0 Geminivirus C4 protein CSN8_PSD8_EIF3K PF10075.9 OAJ25834.1 - 9.6e-27 93.7 0.0 1.8e-26 92.8 0.0 1.5 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Cellulase PF00150.18 OAJ25835.1 - 2.9e-09 36.8 9.7 3.4e-09 36.6 8.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 OAJ25836.1 - 2.4e-18 66.5 0.0 2e-15 56.9 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25836.1 - 1.7e-05 24.3 0.1 0.00089 18.6 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAJ25836.1 - 0.0025 17.8 1.0 0.0041 17.1 0.3 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Alanine_zipper PF11839.8 OAJ25836.1 - 4.7 7.6 12.2 0.29 11.5 1.2 3.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Alpha-amylase PF00128.24 OAJ25837.1 - 2.2e-98 329.9 0.0 3.1e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAJ25837.1 - 0.0036 16.4 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF2838 PF10998.8 OAJ25838.1 - 7.6e-41 138.8 9.0 7.6e-41 138.8 9.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF454 PF04304.13 OAJ25838.1 - 0.032 14.2 3.1 0.85 9.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF454) SMN PF06003.12 OAJ25839.1 - 2.7 7.2 4.3 5.3 6.2 4.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mito_fiss_reg PF05308.11 OAJ25839.1 - 3.7 7.5 5.7 0.39 10.8 1.5 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator AAA_11 PF13086.6 OAJ25840.1 - 7.5e-55 186.5 0.0 7.5e-55 186.5 0.0 3.9 4 1 0 4 4 3 1 AAA domain AAA_12 PF13087.6 OAJ25840.1 - 3.5e-49 167.2 0.0 9.2e-49 165.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ25840.1 - 3.1e-08 33.6 2.5 5.3e-05 23.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ25840.1 - 8.5e-06 26.2 0.1 0.0004 20.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain Viral_helicase1 PF01443.18 OAJ25840.1 - 0.00026 20.8 0.0 0.48 10.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 OAJ25840.1 - 0.00069 20.2 3.0 0.28 11.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.6 OAJ25840.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OAJ25840.1 - 0.0016 18.0 0.3 1.4 8.3 0.0 2.8 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA PF00004.29 OAJ25840.1 - 0.0041 17.6 0.1 0.031 14.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAJ25840.1 - 0.0057 16.3 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ25840.1 - 0.0063 16.8 0.1 0.037 14.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OAJ25840.1 - 0.013 15.9 0.0 0.049 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C PF13361.6 OAJ25840.1 - 0.061 12.7 1.2 1.6 8.0 0.0 3.1 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 OAJ25840.1 - 0.1 11.7 0.0 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase ABC_tran PF00005.27 OAJ25840.1 - 0.66 10.5 3.1 0.78 10.2 0.0 2.6 3 0 0 3 3 2 0 ABC transporter Sporozoite_P67 PF05642.11 OAJ25841.1 - 5 5.1 13.2 6.7 4.7 8.9 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MGC-24 PF05283.11 OAJ25841.1 - 6.2 7.3 13.1 16 5.9 13.1 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mak10 PF04112.13 OAJ25843.1 - 7.2e-46 155.8 0.0 1.4e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AAA PF00004.29 OAJ25849.1 - 1.4e-40 138.7 0.0 3.3e-40 137.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ25849.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ25849.1 - 6.1e-07 30.0 0.5 0.00014 22.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAJ25849.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ25849.1 - 2.7e-06 27.4 0.1 2.9e-05 24.1 0.2 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAJ25849.1 - 3.8e-05 24.3 0.0 0.00076 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ25849.1 - 3.9e-05 23.8 0.0 0.00061 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ25849.1 - 4.6e-05 23.7 0.4 0.0044 17.3 0.3 2.9 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ25849.1 - 0.00021 21.3 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAJ25849.1 - 0.0005 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAJ25849.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 OAJ25849.1 - 0.0026 17.2 0.0 0.62 9.4 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 OAJ25849.1 - 0.0027 18.1 0.0 0.0076 16.6 0.0 1.9 1 1 0 1 1 1 1 RNA helicase TIP49 PF06068.13 OAJ25849.1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 OAJ25849.1 - 0.0034 16.8 0.2 0.011 15.1 0.1 1.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ25849.1 - 0.0042 16.8 0.1 0.007 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAJ25849.1 - 0.0047 17.2 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ25849.1 - 0.0049 16.4 0.2 0.021 14.4 0.2 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region Bac_DnaA PF00308.18 OAJ25849.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 OAJ25849.1 - 0.0067 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.13 OAJ25849.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAJ25849.1 - 0.0087 15.7 0.3 0.086 12.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAJ25849.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 OAJ25849.1 - 0.021 14.2 0.0 0.15 11.4 0.0 2.1 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.17 OAJ25849.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 OAJ25849.1 - 0.023 14.6 0.1 0.17 11.8 0.1 2.3 2 1 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 OAJ25849.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OAJ25849.1 - 0.048 14.1 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ25849.1 - 0.058 13.3 0.0 0.18 11.7 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAJ25849.1 - 0.087 12.7 1.1 4.3 7.2 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea PhoH PF02562.16 OAJ25849.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein S1FA PF04689.13 OAJ25849.1 - 0.1 12.8 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA AAA_21 PF13304.6 OAJ25849.1 - 0.11 12.2 0.5 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_11 PF13086.6 OAJ25849.1 - 0.12 12.1 0.1 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 OAJ25849.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase IPT PF01745.16 OAJ25849.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase FCH PF00611.23 OAJ25849.1 - 0.16 12.3 0.1 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain CPT PF07931.12 OAJ25849.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 OAJ25849.1 - 0.17 12.4 0.1 0.26 11.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OAJ25849.1 - 0.18 11.7 0.3 0.48 10.3 0.1 1.8 2 0 0 2 2 1 0 NACHT domain DUF2075 PF09848.9 OAJ25849.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Homeobox_KN PF05920.11 OAJ25850.1 - 1.7e-17 63.0 3.5 3.2e-17 62.1 3.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAJ25850.1 - 5.9e-05 22.8 2.0 0.00015 21.5 1.1 2.0 2 0 0 2 2 2 1 Homeodomain RhoGEF PF00621.20 OAJ25851.1 - 7.3e-40 137.1 0.1 1.8e-39 135.9 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OAJ25851.1 - 9.8e-10 38.5 0.0 0.00021 21.2 0.0 2.8 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 OAJ25851.1 - 0.00054 20.4 0.0 0.0038 17.7 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 OAJ25851.1 - 0.032 14.6 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Arteri_nucleo PF01481.16 OAJ25851.1 - 0.13 12.5 1.4 0.34 11.2 1.4 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Pannexin_like PF12534.8 OAJ25851.1 - 0.33 10.0 1.5 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 SH3_1 PF00018.28 OAJ25852.1 - 1.2e-17 63.2 0.3 1.3e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAJ25852.1 - 4.3e-17 61.7 0.1 3.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 OAJ25852.1 - 5.4e-16 58.4 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 OAJ25852.1 - 1.2e-09 37.7 0.0 0.0002 21.0 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain WH2 PF02205.20 OAJ25852.1 - 4e-07 29.6 0.2 4e-07 29.6 0.2 2.4 2 0 0 2 2 2 1 WH2 motif EF-hand_1 PF00036.32 OAJ25852.1 - 0.075 12.6 0.0 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 EF hand Serglycin PF04360.12 OAJ25853.1 - 0.068 13.1 1.3 0.22 11.5 1.3 1.8 1 0 0 1 1 1 0 Serglycin Septin PF00735.18 OAJ25855.1 - 4.7e-39 134.4 0.0 1.8e-11 43.9 0.0 4.7 5 0 0 5 5 5 4 Septin TFIIA PF03153.13 OAJ25855.1 - 0.0002 21.5 17.1 0.0002 21.5 17.1 3.3 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit MMR_HSR1 PF01926.23 OAJ25855.1 - 0.055 13.6 0.0 0.44 10.6 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 OAJ25855.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAJ25855.1 - 0.13 11.6 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Nop25 PF09805.9 OAJ25855.1 - 0.18 12.3 40.2 0.057 13.9 31.7 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DNA_pol_phi PF04931.13 OAJ25855.1 - 1.2 7.2 48.3 0.19 9.8 32.3 2.1 2 0 0 2 2 2 0 DNA polymerase phi BUD22 PF09073.10 OAJ25855.1 - 2 7.6 46.5 0.68 9.2 29.5 2.5 2 0 0 2 2 2 0 BUD22 MCM PF00493.23 OAJ25856.1 - 2.1e-100 334.4 0.0 2.9e-100 334.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ25856.1 - 3.6e-37 127.0 0.0 6.2e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 OAJ25856.1 - 2.7e-33 115.4 24.3 2.7e-33 115.4 24.3 3.0 3 1 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 OAJ25856.1 - 6.6e-26 90.6 0.3 2.5e-25 88.7 0.3 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ25856.1 - 5.7e-13 49.4 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ25856.1 - 2.4e-08 33.6 0.0 9e-07 28.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ25856.1 - 3.9e-06 26.9 0.0 8.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAJ25856.1 - 0.00036 20.4 0.0 0.003 17.4 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ25856.1 - 0.019 14.7 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DNA_gyraseB_C PF00986.21 OAJ25856.1 - 0.038 14.2 0.5 2.5 8.3 0.0 3.1 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus AAA_lid_2 PF17863.1 OAJ25856.1 - 0.041 13.7 1.6 0.079 12.8 0.1 2.3 2 0 0 2 2 2 0 AAA lid domain Zn_ribbon_2 PF12674.7 OAJ25856.1 - 0.049 14.3 0.2 0.12 13.0 0.2 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA PF00004.29 OAJ25856.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DHBP_synthase PF00926.19 OAJ25857.1 - 7.3e-75 250.7 0.0 8.7e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-rbx1 PF12678.7 OAJ25858.1 - 5.3e-09 36.2 1.7 9.7e-09 35.4 1.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ25858.1 - 5.1e-08 33.1 4.1 8.3e-08 32.4 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAJ25858.1 - 1.1e-05 25.4 0.6 1.8e-05 24.7 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAJ25858.1 - 3.2e-05 23.7 2.7 5.4e-05 23.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ25858.1 - 0.00016 21.5 1.6 0.00027 20.8 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ25858.1 - 0.00045 20.1 1.8 0.00074 19.4 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ25858.1 - 0.00045 20.0 1.5 0.0008 19.2 1.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAJ25858.1 - 0.0005 19.7 0.1 0.00085 19.0 0.1 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 OAJ25858.1 - 0.018 14.8 1.8 0.031 14.0 1.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OAJ25858.1 - 0.023 14.5 1.6 0.039 13.8 1.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CarbpepA_inh PF02977.15 OAJ25858.1 - 0.2 11.5 0.6 0.42 10.4 0.6 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Zn_ribbon_17 PF17120.5 OAJ25858.1 - 0.36 10.5 3.1 0.65 9.7 3.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OAJ25858.1 - 1.7 9.1 5.3 2.7 8.4 5.3 1.3 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OAJ25858.1 - 1.8 8.8 3.6 3.3 8.0 3.6 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 OAJ25858.1 - 2.8 8.1 5.0 6.1 7.0 5.0 1.5 1 1 0 1 1 1 0 Zinc-finger SOR_SNZ PF01680.17 OAJ25859.1 - 1.9e-112 374.1 5.7 2.6e-112 373.6 5.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAJ25859.1 - 8e-07 28.6 8.3 2.7e-05 23.6 0.8 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAJ25859.1 - 0.00045 19.4 0.5 0.63 9.1 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 OAJ25859.1 - 0.0073 16.3 0.2 0.034 14.2 0.0 2.1 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAJ25859.1 - 0.055 12.8 6.4 0.56 9.5 0.4 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase WD40 PF00400.32 OAJ25860.1 - 0.042 14.7 0.0 0.2 12.6 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Ribosomal_L22 PF00237.19 OAJ25861.1 - 1.6e-34 118.2 0.1 2.2e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Arrestin_C PF02752.22 OAJ25862.1 - 3.7e-10 40.4 0.0 8.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Cyt-b5 PF00173.28 OAJ25863.1 - 5.9e-08 32.7 0.0 7.3e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L23eN PF03939.13 OAJ25864.1 - 1.5e-21 76.4 10.8 2.8e-21 75.5 10.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAJ25864.1 - 1.1e-10 41.7 2.5 1.2e-10 41.6 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 OAJ25864.1 - 0.0088 16.3 0.8 0.012 15.8 0.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) MFS_1 PF07690.16 OAJ25866.1 - 3.6e-25 88.6 68.0 8.9e-20 70.9 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF726 PF05277.12 OAJ25868.1 - 5.9e-120 400.3 3.1 8.1e-120 399.8 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MFS_1 PF07690.16 OAJ25869.1 - 1.8e-26 92.9 30.5 1.8e-26 92.9 30.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 OAJ25869.1 - 0.0031 17.3 0.1 0.0031 17.3 0.1 3.3 4 1 0 4 4 4 1 SRP-independent targeting protein 2/TMEM208 FAM176 PF14851.6 OAJ25869.1 - 0.085 12.5 3.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Cnd2 PF05786.14 OAJ25869.1 - 1.8 7.1 14.9 2.5 6.6 1.8 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 Ytp1 PF10355.9 OAJ25870.1 - 6e-47 160.2 24.2 4.7e-44 150.7 24.2 3.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAJ25870.1 - 8.7e-24 83.3 4.5 8.7e-24 83.3 4.5 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) Arc_PepC_II PF06847.11 OAJ25871.1 - 0.23 12.0 0.4 0.41 11.2 0.4 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Nop14 PF04147.12 OAJ25871.1 - 5.3 5.1 9.4 6.3 4.9 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAJ25871.1 - 9 4.7 5.2 10 4.5 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HisG PF01634.18 OAJ25872.1 - 2.7e-48 163.9 0.0 5.2e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAJ25872.1 - 3.7e-26 91.1 0.1 7.2e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain SBP_bac_3 PF00497.20 OAJ25872.1 - 0.09 12.2 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 PMI_typeI PF01238.21 OAJ25873.1 - 1.6e-53 182.3 0.0 1.1e-52 179.5 0.0 2.1 1 1 0 1 1 1 1 Phosphomannose isomerase type I Chromo PF00385.24 OAJ25874.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain BRO1 PF03097.18 OAJ25884.1 - 2.5e-109 365.6 0.1 5.1e-109 364.6 0.1 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAJ25884.1 - 7.9e-48 163.3 9.5 1.3e-47 162.5 9.5 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Peptidase_M50 PF02163.22 OAJ25885.1 - 3.7e-08 32.9 5.0 0.00076 18.8 0.0 2.9 1 1 1 2 2 2 2 Peptidase family M50 CAP PF00188.26 OAJ25886.1 - 1.2e-18 68.1 1.2 3.2e-18 66.8 1.2 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NOT2_3_5 PF04153.18 OAJ25887.1 - 1.2e-33 116.0 2.6 2.1e-33 115.2 2.6 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Tektin PF03148.14 OAJ25887.1 - 0.24 10.1 2.1 0.32 9.7 2.1 1.1 1 0 0 1 1 1 0 Tektin family Robl_LC7 PF03259.17 OAJ25887.1 - 0.83 9.5 0.0 0.83 9.5 0.0 3.1 3 0 0 3 3 3 0 Roadblock/LC7 domain Folliculin PF11704.8 OAJ25887.1 - 2.6 7.9 4.4 1.3 8.8 1.8 1.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Glyco_hydro_88 PF07470.13 OAJ25889.1 - 1.1e-10 41.1 0.9 8.2e-10 38.3 0.1 2.3 3 0 0 3 3 3 1 Glycosyl Hydrolase Family 88 Torus PF16131.5 OAJ25890.1 - 3.6e-37 127.4 0.5 1.1e-36 125.8 0.5 1.9 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 OAJ25890.1 - 1.6e-08 34.3 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAJ25890.1 - 0.00011 22.1 1.1 0.00019 21.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAJ25890.1 - 0.00015 21.6 1.7 0.00028 20.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAJ25890.1 - 0.048 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Malectin_like PF12819.7 OAJ25890.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Malectin-like domain zf-CCCH_4 PF18044.1 OAJ25890.1 - 0.31 10.9 2.6 0.54 10.1 2.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Strabismus PF06638.11 OAJ25890.1 - 8.7 4.9 6.1 15 4.1 6.1 1.2 1 0 0 1 1 1 0 Strabismus protein Prenyltrans PF00432.21 OAJ25891.1 - 1.4e-47 159.0 5.3 6.3e-11 41.8 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAJ25891.1 - 0.11 11.6 0.0 2.9 6.9 0.0 2.1 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain Helicase_C_4 PF13871.6 OAJ25891.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue PIP5K PF01504.18 OAJ25892.1 - 8.4e-99 330.2 0.0 3.7e-96 321.6 0.0 3.0 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase HemX PF04375.14 OAJ25892.1 - 1.6 8.0 13.1 12 5.1 8.6 2.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Presenilin PF01080.17 OAJ25892.1 - 5.1 5.8 9.5 1.6 7.4 3.3 2.2 2 0 0 2 2 2 0 Presenilin Ndc1_Nup PF09531.10 OAJ25892.1 - 5.9 5.5 16.9 0.17 10.6 9.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Arm PF00514.23 OAJ25893.1 - 7.4e-75 244.9 30.1 8.5e-13 47.9 0.1 12.3 11 1 2 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ25893.1 - 7.5e-19 67.8 11.7 9.1e-05 22.9 0.2 7.5 5 2 2 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 OAJ25893.1 - 1.6e-18 66.9 7.5 0.0058 17.0 0.0 7.1 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 OAJ25893.1 - 8.9e-15 53.5 12.9 0.87 10.0 0.0 9.1 8 0 0 8 8 8 5 HEAT repeat Adaptin_N PF01602.20 OAJ25893.1 - 2.7e-10 39.4 12.4 1.4e-08 33.8 0.9 2.4 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 OAJ25893.1 - 3.1e-10 38.9 1.8 4.7e-10 38.3 1.8 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 OAJ25893.1 - 1.3e-09 37.8 8.7 0.0008 18.8 1.3 4.5 1 1 2 4 4 4 4 V-ATPase subunit H Arm_2 PF04826.13 OAJ25893.1 - 2e-09 37.3 10.4 5.7e-06 26.0 4.1 2.8 1 1 1 2 2 2 2 Armadillo-like Cnd1 PF12717.7 OAJ25893.1 - 2.1e-06 27.9 8.0 0.056 13.5 0.7 4.5 2 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAJ25893.1 - 3e-06 27.3 13.4 0.0017 18.3 0.2 4.4 2 1 2 5 5 5 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 OAJ25893.1 - 5.6e-05 22.7 8.8 0.47 9.8 1.8 4.2 2 1 2 4 4 4 2 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 OAJ25893.1 - 6.6e-05 23.0 5.5 4.5 7.4 0.0 5.1 2 1 3 5 5 5 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 OAJ25893.1 - 0.023 15.3 0.1 3.4 8.3 0.0 3.2 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 OAJ25893.1 - 0.024 14.6 5.4 3.2 7.7 0.4 3.7 3 1 0 4 4 4 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 OAJ25893.1 - 0.025 15.2 9.8 1.1e+02 3.9 0.0 7.4 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat IFRD PF05004.13 OAJ25893.1 - 0.031 13.4 8.5 0.93 8.5 0.1 4.2 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) YqfD PF06898.11 OAJ25893.1 - 0.032 13.1 0.0 0.075 11.9 0.0 1.5 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD CTNNBL PF08216.11 OAJ25893.1 - 0.14 12.3 7.2 46 4.2 0.2 5.0 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 OAJ25893.1 - 0.19 11.7 3.4 2.4 8.2 0.0 3.6 2 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Dabb PF07876.12 OAJ25894.1 - 4.3e-19 68.9 0.0 4.9e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Sporozoite_P67 PF05642.11 OAJ25895.1 - 0.15 10.1 9.0 0.21 9.6 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.19 OAJ25895.1 - 0.36 10.7 13.4 0.74 9.7 13.4 1.5 1 1 0 1 1 1 0 SPX domain Macoilin PF09726.9 OAJ25895.1 - 0.75 8.3 10.0 1.1 7.8 10.0 1.2 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 OAJ25895.1 - 0.85 8.7 6.4 0.22 10.6 3.5 1.4 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S64 PF08192.11 OAJ25895.1 - 1.4 7.3 9.9 2.2 6.7 9.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 FAM199X PF15814.5 OAJ25895.1 - 6.5 5.7 20.3 11 5.0 20.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X AF-4 PF05110.13 OAJ25895.1 - 7.3 4.5 25.9 11 3.9 25.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Chorismate_bind PF00425.18 OAJ25896.1 - 1.2e-74 251.1 0.0 3e-74 249.9 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 OAJ25896.1 - 9.6e-26 90.7 0.0 2.7e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAJ25896.1 - 1.1e-14 54.8 0.0 3.4e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAJ25896.1 - 0.0045 16.8 0.2 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 DDE_Tnp_4 PF13359.6 OAJ25898.1 - 1.4e-33 115.8 0.0 2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ25898.1 - 1.4e-05 24.8 0.0 0.00018 21.2 0.0 2.5 2 1 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ25898.1 - 4.3e-05 23.3 0.1 0.00011 21.9 0.1 1.7 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 OAJ25898.1 - 0.008 15.9 0.0 0.027 14.2 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 OAJ25898.1 - 0.045 14.1 0.1 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain MULE PF10551.9 OAJ25899.1 - 9.3e-08 32.4 0.0 2.8e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ25899.1 - 5.8e-05 22.7 1.9 0.00016 21.2 1.9 1.8 1 0 0 1 1 1 1 SWIM zinc finger HTH_Tnp_ISL3 PF13542.6 OAJ25899.1 - 0.055 12.9 0.2 0.15 11.5 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DDE_Tnp_IS240 PF13610.6 OAJ25899.1 - 0.088 13.0 0.0 9.1 6.5 0.0 2.9 3 0 0 3 3 3 0 DDE domain Sporozoite_P67 PF05642.11 OAJ25899.1 - 0.36 8.9 3.5 0.52 8.3 3.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 OAJ25899.1 - 2.4 6.2 7.6 3.6 5.6 7.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RAP1 PF07218.11 OAJ25899.1 - 4.4 5.4 4.9 6.5 4.9 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M16_C PF05193.21 OAJ25900.1 - 4.9e-20 72.3 0.0 6.9e-16 58.8 0.0 3.1 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAJ25900.1 - 8.2e-08 32.4 0.0 4.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Oxysterol_BP PF01237.18 OAJ25900.1 - 0.18 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein HRDC PF00570.23 OAJ25901.1 - 0.0002 21.3 0.1 0.96 9.5 0.0 2.5 2 0 0 2 2 2 2 HRDC domain STPPase_N PF16891.5 OAJ25901.1 - 0.002 18.5 0.1 3.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Serine-threonine protein phosphatase N-terminal domain Gram_pos_anchor PF00746.21 OAJ25901.1 - 0.068 13.1 0.0 21 5.2 0.0 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TetR_C_28 PF17937.1 OAJ25901.1 - 0.072 13.6 9.2 1.8 9.1 0.5 3.2 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Skp1_POZ PF03931.15 OAJ25901.1 - 0.22 11.7 0.0 33 4.8 0.0 2.3 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Chromo PF00385.24 OAJ25904.1 - 5.5e-06 26.2 0.4 9.8e-06 25.4 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Imm5 PF14423.6 OAJ25904.1 - 0.24 11.6 1.1 0.91 9.7 1.1 2.0 1 0 0 1 1 1 0 Immunity protein Imm5 zf-C2H2 PF00096.26 OAJ25905.1 - 3.2e-06 27.3 18.4 7.5e-05 23.0 1.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ25905.1 - 0.00024 21.4 2.1 0.00024 21.4 2.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ25905.1 - 0.00086 20.0 1.2 0.00086 20.0 1.2 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ25905.1 - 0.003 17.5 0.1 0.0076 16.2 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ25905.1 - 0.011 16.1 0.3 0.011 16.1 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ25905.1 - 0.06 13.8 0.2 0.06 13.8 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAJ25905.1 - 0.076 13.7 11.6 0.11 13.2 0.3 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 OAJ25905.1 - 0.84 9.6 3.2 0.7 9.9 1.6 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Colicin_im PF03857.13 OAJ25906.1 - 0.052 13.5 0.2 0.3 11.1 0.1 2.1 1 1 1 2 2 2 0 Colicin immunity protein Chitin_synth_1 PF01644.17 OAJ25907.1 - 4.7e-67 225.0 1.6 7.3e-67 224.4 1.6 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OAJ25907.1 - 2.5e-22 79.2 0.0 4.1e-18 65.3 0.0 2.8 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 OAJ25907.1 - 5.3e-22 77.5 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 OAJ25907.1 - 2e-06 27.8 0.4 2e-06 27.8 0.4 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Amino_oxidase PF01593.24 OAJ25914.1 - 1.6e-57 195.8 0.0 1.9e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ25914.1 - 8.9e-10 38.7 0.2 1.9e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ25914.1 - 1e-06 28.6 0.1 2.2e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ25914.1 - 2.6e-06 26.4 0.5 0.0031 16.3 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAJ25914.1 - 8.6e-05 23.0 0.4 0.0084 16.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ25914.1 - 0.00022 20.5 0.2 0.00032 19.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ25914.1 - 0.00022 20.6 0.8 0.022 14.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ25914.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ25914.1 - 0.00086 18.6 1.4 0.0056 15.9 0.9 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ25914.1 - 0.0011 18.9 0.1 1.8 8.5 0.2 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 OAJ25914.1 - 0.0031 16.8 0.4 0.0059 15.9 0.4 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAJ25914.1 - 0.0036 16.7 0.4 0.0057 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ25914.1 - 0.021 13.9 0.1 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein MCRA PF06100.11 OAJ25914.1 - 0.096 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 MCRA family GATase_3 PF07685.14 OAJ25914.1 - 0.12 12.0 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain GIDA PF01134.22 OAJ25914.1 - 0.14 11.2 0.8 2.5 7.1 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A CxC4 PF18717.1 OAJ25915.1 - 3.1e-34 117.6 1.3 1e-33 116.0 1.3 2.0 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases SWIM PF04434.17 OAJ25915.1 - 0.33 10.7 8.0 1.5 8.5 0.2 3.5 3 0 0 3 3 3 0 SWIM zinc finger BolA PF01722.18 OAJ25916.1 - 7e-16 58.3 0.1 1.1e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 BolA-like protein AAA_5 PF07728.14 OAJ25917.1 - 1.6e-113 374.8 0.2 1.9e-19 70.0 0.0 10.2 9 1 1 10 10 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAJ25917.1 - 2.1e-44 150.0 2.3 2.2e-15 56.8 0.0 4.6 3 0 0 3 3 3 3 Midasin AAA lid domain AAA_7 PF12775.7 OAJ25917.1 - 5e-27 94.6 0.5 1.5e-06 27.8 0.0 7.2 7 0 0 7 7 7 4 P-loop containing dynein motor region AAA PF00004.29 OAJ25917.1 - 1.7e-26 93.2 0.2 0.0056 17.1 0.0 7.9 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 OAJ25917.1 - 3.2e-25 88.5 0.0 6.9e-08 32.4 0.0 7.7 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 OAJ25917.1 - 3.1e-22 78.6 0.0 9.6e-22 77.1 0.0 1.9 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 OAJ25917.1 - 2.4e-21 76.9 44.7 0.00011 22.6 0.4 12.1 10 4 0 11 11 9 6 AAA ATPase domain AAA_22 PF13401.6 OAJ25917.1 - 3.4e-20 72.7 3.6 0.0043 17.3 0.0 8.3 8 0 0 8 8 7 3 AAA domain ABC_tran PF00005.27 OAJ25917.1 - 1.9e-17 64.0 0.2 0.0031 18.0 0.0 6.9 6 1 0 6 6 5 3 ABC transporter AAA_6 PF12774.7 OAJ25917.1 - 7.7e-17 61.3 0.2 0.014 14.4 0.0 6.8 6 0 0 6 6 6 4 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 OAJ25917.1 - 1.1e-16 61.0 0.0 0.031 14.3 0.0 7.1 6 0 0 6 6 6 3 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 OAJ25917.1 - 4e-16 59.2 0.1 0.0049 16.6 0.0 5.9 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_18 PF13238.6 OAJ25917.1 - 2.6e-15 57.1 0.4 0.09 13.3 0.0 7.2 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 OAJ25917.1 - 1.4e-14 54.3 10.1 0.15 11.8 0.0 8.7 7 1 0 7 7 7 4 AAA domain TsaE PF02367.17 OAJ25917.1 - 3.9e-14 52.7 4.8 0.089 12.8 0.1 7.1 7 0 0 7 7 7 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ25917.1 - 1.3e-13 51.3 2.5 0.0095 16.1 0.2 7.3 6 0 0 6 6 6 2 AAA domain NACHT PF05729.12 OAJ25917.1 - 3.7e-12 46.5 2.1 0.0036 17.2 0.0 6.3 5 0 0 5 5 5 2 NACHT domain AAA_14 PF13173.6 OAJ25917.1 - 8e-11 42.1 0.0 0.071 13.1 0.0 6.6 8 0 0 8 8 5 2 AAA domain AAA_19 PF13245.6 OAJ25917.1 - 5.9e-10 39.7 8.8 0.23 11.8 0.1 6.9 6 1 0 6 6 5 2 AAA domain AAA_28 PF13521.6 OAJ25917.1 - 1e-09 38.9 8.0 1.7 8.9 0.0 7.5 6 0 0 6 6 6 1 AAA domain AAA_29 PF13555.6 OAJ25917.1 - 1.2e-09 37.8 1.3 0.28 11.0 0.0 6.0 6 0 0 6 6 5 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAJ25917.1 - 2.4e-09 37.6 0.6 1.3 9.4 0.0 6.7 6 0 0 6 6 6 1 RNA helicase RsgA_GTPase PF03193.16 OAJ25917.1 - 5.9e-09 36.1 4.2 0.13 12.1 0.0 6.3 6 1 1 7 7 6 2 RsgA GTPase Mg_chelatase PF01078.21 OAJ25917.1 - 6.5e-09 35.5 5.3 0.13 11.6 0.1 7.8 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAJ25917.1 - 9.8e-09 34.8 2.5 0.21 10.8 0.0 6.3 6 0 0 6 6 6 1 Zeta toxin Sigma54_activ_2 PF14532.6 OAJ25917.1 - 1.1e-08 35.2 0.5 0.41 10.8 0.0 6.0 5 0 0 5 5 5 2 Sigma-54 interaction domain T2SSE PF00437.20 OAJ25917.1 - 2.5e-08 33.3 7.0 0.13 11.3 0.0 6.6 6 0 0 6 6 6 1 Type II/IV secretion system protein DUF815 PF05673.13 OAJ25917.1 - 6.8e-08 32.0 2.4 0.4 9.8 0.0 6.0 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAJ25917.1 - 2.6e-07 30.4 15.2 0.83 9.2 0.1 6.8 7 0 0 7 7 6 2 AAA domain IstB_IS21 PF01695.17 OAJ25917.1 - 2.7e-07 30.5 1.1 1 9.1 0.0 5.9 6 0 0 6 6 6 1 IstB-like ATP binding protein Roc PF08477.13 OAJ25917.1 - 1.1e-06 28.9 1.3 3.6 7.8 0.0 5.9 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ25917.1 - 1.5e-06 28.1 1.0 2.5 7.8 0.0 6.0 6 0 0 6 6 6 1 AAA domain TniB PF05621.11 OAJ25917.1 - 2.1e-06 27.3 0.0 4.3 6.7 0.0 5.2 5 0 0 5 5 5 0 Bacterial TniB protein PduV-EutP PF10662.9 OAJ25917.1 - 2.9e-06 27.1 2.1 0.52 10.1 0.0 5.2 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 OAJ25917.1 - 1.5e-05 25.0 0.6 1.4 8.8 0.0 5.2 5 0 0 5 5 5 1 Rad17 P-loop domain ResIII PF04851.15 OAJ25917.1 - 2e-05 24.7 0.1 5.5 7.0 0.0 5.4 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 OAJ25917.1 - 4.8e-05 23.3 2.8 11 5.7 0.0 5.6 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ25917.1 - 0.00012 22.1 0.5 34 4.6 0.0 6.0 6 0 0 6 6 5 0 50S ribosome-binding GTPase SRP54 PF00448.22 OAJ25917.1 - 0.00014 21.6 5.6 1.1 8.8 0.0 5.4 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain RuvB_N PF05496.12 OAJ25917.1 - 0.00024 20.9 4.8 18 5.0 0.0 6.6 7 0 0 7 7 7 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OAJ25917.1 - 0.00033 20.1 1.0 7.3 5.9 0.0 4.8 5 0 0 5 5 5 0 KaiC AAA_8 PF12780.7 OAJ25917.1 - 0.00057 19.3 0.1 13 5.0 0.0 4.6 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 MeaB PF03308.16 OAJ25917.1 - 0.00067 18.7 2.5 0.92 8.4 0.0 3.4 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP49 PF06068.13 OAJ25917.1 - 0.0011 18.3 3.7 3.3 6.8 0.0 4.7 5 0 0 5 5 5 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 OAJ25917.1 - 0.0016 18.3 0.2 17 5.1 0.0 5.3 6 0 0 6 6 5 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 OAJ25917.1 - 0.0016 18.1 8.4 7.3 6.1 0.0 5.5 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 OAJ25917.1 - 0.0029 17.0 0.4 38 3.6 0.0 5.5 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit PhoH PF02562.16 OAJ25917.1 - 0.0036 16.8 2.7 3.4 7.1 0.1 4.0 4 0 0 4 4 4 0 PhoH-like protein CPT PF07931.12 OAJ25917.1 - 0.0078 16.1 9.5 1.8 8.4 0.0 7.5 10 1 0 10 10 7 1 Chloramphenicol phosphotransferase-like protein ATP_bind_1 PF03029.17 OAJ25917.1 - 0.0091 15.8 2.1 12 5.6 0.1 4.4 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein MCM PF00493.23 OAJ25917.1 - 0.01 14.9 0.2 25 3.9 0.0 4.4 5 0 0 5 5 4 0 MCM P-loop domain ATPase_2 PF01637.18 OAJ25917.1 - 0.015 15.2 0.0 23 4.8 0.0 4.3 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAJ25917.1 - 0.017 15.0 3.9 5.4 6.9 0.1 5.0 5 0 0 5 5 5 0 NTPase dNK PF01712.19 OAJ25917.1 - 0.038 13.8 2.5 26 4.6 0.0 4.2 5 0 0 5 5 4 0 Deoxynucleoside kinase AAA_23 PF13476.6 OAJ25917.1 - 0.05 14.1 0.0 0.05 14.1 0.0 7.6 7 1 0 7 7 6 0 AAA domain IPT PF01745.16 OAJ25917.1 - 0.051 13.0 1.4 26 4.1 0.0 3.9 4 0 0 4 4 4 0 Isopentenyl transferase Bac_DnaA PF00308.18 OAJ25917.1 - 0.059 13.2 0.0 7.6 6.3 0.0 3.3 3 0 0 3 3 2 0 Bacterial dnaA protein Ploopntkinase3 PF18751.1 OAJ25917.1 - 0.086 12.7 0.2 20 5.0 0.0 3.7 4 0 0 4 4 3 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 OAJ25917.1 - 0.092 12.1 4.0 4.4 6.6 0.1 4.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family Coiled-coil_56 PF09813.9 OAJ25918.1 - 0.0054 16.8 0.2 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 Apolipoprotein PF01442.18 OAJ25918.1 - 0.014 15.3 2.8 0.019 14.9 2.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAJ25918.1 - 0.057 14.0 7.0 0.078 13.6 5.6 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Aminotran_5 PF00266.19 OAJ25918.1 - 0.063 12.2 1.1 0.087 11.8 1.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V EIIBC-GUT_N PF03612.14 OAJ25918.1 - 0.19 11.4 0.5 0.28 10.9 0.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Inv-AAD PF18785.1 OAJ25919.1 - 5.8e-24 84.4 0.0 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAJ25919.1 - 9.8e-12 44.7 0.1 1.9e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 OAJ25919.1 - 5.5e-08 32.9 0.1 7.7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 OAJ25919.1 - 0.0055 16.8 0.0 0.0099 16.0 0.0 1.5 1 1 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 OAJ25919.1 - 0.014 15.5 0.0 0.084 13.0 0.0 2.1 1 1 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 OAJ25919.1 - 0.07 13.2 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 APOBEC2 AMP-binding PF00501.28 OAJ25920.1 - 1.5e-89 300.5 0.1 2e-89 300.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ25920.1 - 0.0026 18.7 0.0 0.0097 16.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 OAJ25921.1 - 3.6e-34 117.7 0.3 4.4e-34 117.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ25921.1 - 2.5e-26 92.2 0.1 4.1e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ25921.1 - 9.6e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ25921.1 - 4.3e-07 29.5 0.3 5.6e-07 29.1 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MID_MedPIWI PF18296.1 OAJ25921.1 - 0.024 14.4 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 MID domain of medPIWI G-alpha PF00503.20 OAJ25921.1 - 0.034 13.3 3.0 0.11 11.7 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 OAJ25921.1 - 0.05 13.7 0.0 0.079 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ25921.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OAJ25921.1 - 0.097 12.1 0.0 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein DLIC PF05783.11 OAJ25921.1 - 0.13 11.1 8.7 0.16 10.8 0.0 2.9 1 1 2 3 3 3 0 Dynein light intermediate chain (DLIC) Utp21 PF04192.12 OAJ25922.1 - 2.7e-52 177.6 0.0 9.1e-52 175.9 0.0 1.8 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAJ25922.1 - 1.4e-15 57.4 0.0 0.0013 19.0 0.0 7.4 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ25922.1 - 1.4e-09 38.4 11.0 0.019 15.8 0.1 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAJ25922.1 - 0.013 15.5 0.0 0.32 11.1 0.0 3.2 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OAJ25922.1 - 0.015 14.3 0.0 4 6.3 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OAJ25922.1 - 0.019 15.4 3.6 7.4 7.2 0.5 5.2 4 1 0 4 4 4 0 PQQ-like domain PBP1_TM PF14812.6 OAJ25922.1 - 0.064 13.6 1.7 0.18 12.2 1.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PD40 PF07676.12 OAJ25922.1 - 0.083 12.9 0.3 0.28 11.2 0.3 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SR-25 PF10500.9 OAJ25922.1 - 7.7 6.1 19.3 0.16 11.5 12.2 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ThiF PF00899.21 OAJ25923.1 - 1.2e-58 198.4 0.0 1.7e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OAJ25923.1 - 1.1e-05 25.9 0.0 3.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.6 OAJ25923.1 - 1.2e-05 25.7 0.1 2.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAJ25923.1 - 2.6e-05 24.3 0.1 0.00025 21.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAJ25923.1 - 0.0062 16.1 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 OAJ25923.1 - 0.13 11.8 0.3 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GCV_H PF01597.19 OAJ25923.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein AMP-binding PF00501.28 OAJ25924.1 - 6.1e-91 305.1 0.1 7.8e-88 294.9 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ25924.1 - 1.4e-10 42.0 0.3 4.1e-10 40.5 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NARP1 PF12569.8 OAJ25925.1 - 1.1e-152 509.5 7.1 1.1e-151 506.2 7.1 2.1 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 OAJ25925.1 - 8.1e-12 44.3 26.6 1.9e-05 24.4 0.0 10.1 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ25925.1 - 1.4e-11 43.6 6.1 0.0019 18.1 0.0 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ25925.1 - 1.7e-11 43.4 3.2 4.2e-05 23.2 0.1 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ25925.1 - 1.9e-10 40.7 31.3 0.022 15.6 0.1 10.6 11 1 1 12 12 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ25925.1 - 7.7e-08 32.4 11.1 0.00033 20.7 0.3 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ25925.1 - 4.9e-07 30.2 40.8 0.072 13.6 0.0 9.4 8 2 1 9 9 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ25925.1 - 1.2e-06 28.7 15.9 0.031 14.6 0.1 6.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ25925.1 - 6.9e-06 26.1 0.2 3.5 8.2 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ25925.1 - 0.0079 16.3 16.2 0.39 11.0 0.1 7.2 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ25925.1 - 0.011 16.3 14.6 0.059 14.0 0.1 6.9 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ25925.1 - 0.03 15.0 0.0 0.07 13.8 0.0 10.7 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ25925.1 - 0.031 13.9 5.1 2.1 8.1 0.0 4.5 5 0 0 5 5 5 0 TPR repeat Fis1_TPR_C PF14853.6 OAJ25925.1 - 0.033 14.3 0.3 31 4.7 0.0 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF789 PF05623.12 OAJ25925.1 - 0.05 13.3 0.3 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) TPR_10 PF13374.6 OAJ25925.1 - 0.052 13.4 6.5 11 6.0 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TAF4 PF05236.14 OAJ25925.1 - 0.36 10.5 11.3 0.86 9.3 11.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RNA_pol_Rpc4 PF05132.14 OAJ25925.1 - 8.7 6.8 7.8 31 5.0 7.8 1.9 1 0 0 1 1 1 0 RNA polymerase III RPC4 Fibrinogen_BP PF08017.11 OAJ25926.1 - 0.042 12.3 1.9 0.086 11.3 1.9 1.4 1 0 0 1 1 1 0 Fibrinogen binding protein zf-C2H2_4 PF13894.6 OAJ25926.1 - 0.77 10.8 5.2 0.2 12.6 1.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger BAF1_ABF1 PF04684.13 OAJ25926.1 - 2 7.4 7.8 1.2 8.1 1.6 2.7 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.25 OAJ25927.1 - 1.7e-64 217.7 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25927.1 - 7.8e-29 100.7 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ25927.1 - 3.7e-15 56.3 0.7 3.7e-15 56.3 0.7 2.9 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAJ25927.1 - 3.9e-08 33.0 0.0 8.3e-07 28.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 OAJ25927.1 - 3.1e-07 30.6 0.1 0.00081 19.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 OAJ25927.1 - 0.0082 15.1 0.1 0.0082 15.1 0.1 1.7 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 OAJ25927.1 - 0.014 15.0 0.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAJ25927.1 - 0.05 13.5 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 OAJ25928.1 - 1.4e-18 66.5 0.1 2.6e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ25928.1 - 2e-08 33.8 0.0 4.6e-06 26.2 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ25928.1 - 0.0067 16.3 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF1027 PF06265.11 OAJ25928.1 - 0.044 13.8 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Limkain-b1 PF11608.8 OAJ25928.1 - 0.056 13.5 0.2 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DUF4523 PF15023.6 OAJ25928.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Ish1 PF10281.9 OAJ25929.1 - 1.2e-60 201.5 26.0 3.1e-13 49.8 0.3 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.27 OAJ25929.1 - 0.00043 19.9 0.0 1.3 8.9 0.0 4.2 4 0 0 4 4 4 1 SAP domain GYF PF02213.16 OAJ25929.1 - 0.00048 19.7 2.0 0.034 13.8 0.1 2.6 2 0 0 2 2 2 2 GYF domain LEM PF03020.15 OAJ25929.1 - 0.0059 16.1 0.0 3.3 7.3 0.0 3.6 4 0 0 4 4 4 1 LEM domain HeH PF12949.7 OAJ25929.1 - 0.46 10.2 5.4 2.3 8.0 0.0 4.3 6 0 0 6 6 6 0 HeH/LEM domain Peptidase_S49 PF01343.18 OAJ25930.1 - 0.019 14.9 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 DUF1467 PF07330.12 OAJ25930.1 - 0.78 9.7 2.8 24 4.9 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1467) Homeobox_KN PF05920.11 OAJ25931.1 - 1.2e-12 47.4 0.0 1.1e-09 38.0 0.0 2.8 2 0 0 2 2 2 2 Homeobox KN domain Trp_DMAT PF11991.8 OAJ25931.1 - 3.9e-05 23.2 0.1 0.25 10.7 0.0 2.3 2 0 0 2 2 2 2 Tryptophan dimethylallyltransferase RRN3 PF05327.11 OAJ25931.1 - 0.017 13.7 1.5 0.63 8.5 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5004 PF16395.5 OAJ25931.1 - 0.034 14.2 2.6 1.6 8.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5004) TraU PF06834.11 OAJ25931.1 - 0.055 12.7 1.6 1.2 8.3 0.1 2.8 3 0 0 3 3 3 0 TraU protein Homeodomain PF00046.29 OAJ25931.1 - 0.058 13.3 0.7 4.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Homeodomain HA2 PF04408.23 OAJ25931.1 - 0.064 13.5 0.6 5.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF2695 PF10905.8 OAJ25931.1 - 0.073 13.3 0.1 23 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) NPP PF08384.10 OAJ25931.1 - 0.16 12.0 0.0 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region DUF4611 PF15387.6 OAJ25931.1 - 0.27 11.5 5.3 2.4 8.4 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CWC25 PF12542.8 OAJ25931.1 - 2.7 8.9 10.2 1.6 9.7 1.0 2.8 3 0 0 3 3 2 0 Pre-mRNA splicing factor NKAP PF15692.5 OAJ25931.1 - 5.6 7.8 10.0 21 5.9 1.1 2.6 2 0 0 2 2 2 0 NF-kappa-B-activating protein Mucin PF01456.17 OAJ25932.1 - 0.0033 17.4 17.8 0.04 13.9 9.1 2.5 2 1 0 2 2 2 2 Mucin-like glycoprotein Pescadillo_N PF06732.11 OAJ25933.1 - 9.6e-120 399.2 0.0 2.1e-119 398.1 0.0 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAJ25933.1 - 4e-07 30.4 0.2 2.2e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAJ25933.1 - 0.00011 22.5 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAJ25933.1 - 0.0087 16.3 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain MMM1 PF10296.9 OAJ25934.1 - 0.00013 21.2 0.0 0.0005 19.2 0.0 1.9 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Pkinase PF00069.25 OAJ25935.1 - 2.1e-27 96.2 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25935.1 - 5e-16 58.8 0.0 6.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ25935.1 - 1.7e-09 37.0 0.1 1.7e-09 37.0 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAJ25935.1 - 0.00011 22.3 1.2 0.0081 16.1 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ25935.1 - 0.038 13.3 0.3 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAJ25935.1 - 0.04 12.9 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_S21e PF01249.18 OAJ25939.1 - 1.7e-35 121.0 0.0 1.9e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FliMN_C PF01052.20 OAJ25939.1 - 0.039 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Kinesin PF00225.23 OAJ25940.1 - 6.5e-110 367.2 0.0 6.5e-110 367.2 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ25940.1 - 3.1e-26 92.1 0.0 1.5e-25 89.9 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 OAJ25940.1 - 8e-05 23.0 12.5 8e-05 23.0 12.5 4.4 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Sox_N PF12444.8 OAJ25940.1 - 0.017 16.2 2.0 0.19 12.9 0.0 3.8 3 0 0 3 3 3 0 Sox developmental protein N terminal HOOK PF05622.12 OAJ25940.1 - 6 4.9 79.8 0.16 10.1 24.4 3.2 1 1 1 2 2 2 0 HOOK protein Clathrin PF00637.20 OAJ25941.1 - 2.8e-27 95.3 0.0 5.9e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-rbx1 PF12678.7 OAJ25941.1 - 0.0086 16.3 0.2 0.0086 16.3 0.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAJ25941.1 - 0.023 14.5 0.2 0.048 13.4 0.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 OAJ25941.1 - 0.13 13.2 1.1 0.26 12.2 0.1 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Na_trans_assoc PF06512.13 OAJ25941.1 - 1.1 9.5 8.0 1.9 8.7 8.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated zf-RING_2 PF13639.6 OAJ25941.1 - 1.3 9.4 3.5 2.9 8.3 0.3 2.6 2 0 0 2 2 2 0 Ring finger domain NDUF_B4 PF07225.12 OAJ25942.1 - 0.054 13.4 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF1754 PF08555.10 OAJ25943.1 - 7.8e-12 45.9 6.4 7.8e-12 45.9 6.4 1.9 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MCM3AP_GANP PF16769.5 OAJ25943.1 - 0.0056 15.0 3.1 0.0067 14.7 3.1 1.0 1 0 0 1 1 1 1 MCM3AP domain of GANP CAML PF14963.6 OAJ25943.1 - 0.099 12.8 6.4 0.12 12.5 6.4 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand FAM199X PF15814.5 OAJ25943.1 - 0.36 9.8 10.8 0.43 9.6 10.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X Ribosomal_L21p PF00829.21 OAJ25944.1 - 2.2e-18 66.4 0.8 2.3e-13 50.3 1.2 2.1 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein SAP130_C PF16014.5 OAJ25944.1 - 0.03 13.4 9.5 0.05 12.7 9.5 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Nucleoside_tran PF01733.18 OAJ25945.1 - 4e-21 75.7 9.5 1.1e-18 67.7 3.9 3.6 2 1 1 3 3 3 2 Nucleoside transporter Med11 PF10280.9 OAJ25945.1 - 0.024 15.1 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Mediator complex protein Pkinase PF00069.25 OAJ25946.1 - 4.5e-24 85.2 0.0 6.3e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25946.1 - 9.2e-14 51.3 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ25946.1 - 0.00067 19.1 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HemX PF04375.14 OAJ25947.1 - 0.028 13.7 25.9 0.43 9.8 10.1 2.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FUSC PF04632.12 OAJ25947.1 - 0.18 10.3 11.7 0.079 11.5 8.6 2.0 1 1 0 1 1 1 0 Fusaric acid resistance protein family Mannitol_dh PF01232.23 OAJ25947.1 - 0.78 9.9 0.0 0.78 9.9 0.0 2.5 3 1 0 3 3 3 0 Mannitol dehydrogenase Rossmann domain DUF812 PF05667.11 OAJ25947.1 - 6 5.6 41.7 0.063 12.2 5.2 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF812) MutS_III PF05192.18 OAJ25948.1 - 0.031 14.5 0.9 0.039 14.2 0.9 1.1 1 0 0 1 1 1 0 MutS domain III ResIII PF04851.15 OAJ25948.1 - 0.043 13.8 0.3 0.059 13.4 0.3 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1045 PF06299.12 OAJ25948.1 - 0.11 12.4 2.0 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) DUF4061 PF13270.6 OAJ25948.1 - 0.18 12.1 4.1 2.1 8.7 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DUF1640 PF07798.11 OAJ25948.1 - 0.22 11.6 5.7 0.37 10.8 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Longin PF13774.6 OAJ25949.1 - 5.8e-21 74.3 0.0 9.7e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OAJ25949.1 - 1.4e-13 50.4 0.2 3.3e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin Glyco_hydro_63 PF03200.16 OAJ25952.1 - 1.9e-161 538.1 0.0 2.1e-160 534.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAJ25952.1 - 3.1e-69 233.5 0.5 2.4e-67 227.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAJ25952.1 - 4.8e-05 22.4 0.1 6.6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Trehalase IHABP4_N PF16174.5 OAJ25953.1 - 0.9 10.1 2.6 2.2 8.8 2.6 1.8 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal HLH PF00010.26 OAJ25954.1 - 3.1e-07 30.2 0.3 9.5e-07 28.7 0.3 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Angiomotin_C PF12240.8 OAJ25954.1 - 0.00091 18.8 1.2 0.00091 18.8 1.2 3.1 3 0 0 3 3 3 1 Angiomotin C terminal Spt20 PF12090.8 OAJ25954.1 - 0.45 10.1 42.1 0.24 11.0 20.3 2.6 2 0 0 2 2 2 0 Spt20 family EIIBC-GUT_N PF03612.14 OAJ25954.1 - 2.7 7.7 6.4 1.9 8.2 1.4 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 OAJ25954.1 - 4.6 7.6 17.2 3.4 8.0 4.7 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like Citrate_synt PF00285.21 OAJ25955.1 - 1.2e-91 307.5 0.0 1.5e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain OPT PF03169.15 OAJ25956.1 - 5.8e-131 438.1 3.0 8.3e-131 437.6 3.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.7 OAJ25957.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like AAA_2 PF07724.14 OAJ25958.1 - 5.1e-31 108.1 0.0 1.7e-23 83.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAJ25958.1 - 1.7e-12 47.9 0.0 3.8e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAJ25958.1 - 5.4e-11 42.4 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 OAJ25958.1 - 2.3e-05 23.6 0.0 7.3e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 OAJ25958.1 - 4.4e-05 23.8 0.2 0.00024 21.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAJ25958.1 - 0.0001 22.3 0.0 0.0003 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ25958.1 - 0.0032 17.9 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAJ25958.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 OAJ25958.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ25958.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ25958.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 OAJ25958.1 - 0.077 13.0 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAJ25958.1 - 0.078 13.5 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OAJ25958.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAJ25958.1 - 0.1 12.0 1.4 0.67 9.3 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ25958.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_ligase_A_C PF04679.15 OAJ25959.1 - 7.9e-21 74.5 0.0 9.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 OAJ25959.1 - 0.048 13.7 0.2 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 OAJ25960.1 - 4.6e-61 206.0 0.1 9.6e-61 205.0 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ25960.1 - 6.5e-46 156.8 0.1 1.3e-45 155.9 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 OAJ25960.1 - 5.5e-05 23.5 0.1 0.00014 22.2 0.1 1.7 2 0 0 2 2 2 1 RNA ligase SMC_N PF02463.19 OAJ25961.1 - 6.8e-70 234.9 0.0 5.6e-68 228.7 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ25961.1 - 7.5e-19 68.2 0.5 3.5e-18 66.0 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ25961.1 - 2.1e-14 54.5 16.4 2.1e-14 54.5 16.4 6.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 OAJ25961.1 - 6e-11 42.7 12.4 3.6e-05 23.7 0.3 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ25961.1 - 4.4e-05 23.1 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lebercilin PF15619.6 OAJ25961.1 - 0.0019 17.9 13.2 0.0019 17.9 13.2 7.4 5 3 3 8 8 8 1 Ciliary protein causing Leber congenital amaurosis disease FliJ PF02050.16 OAJ25961.1 - 0.0074 16.5 13.0 0.0074 16.5 13.0 9.1 5 3 5 10 10 10 1 Flagellar FliJ protein IGR PF09597.10 OAJ25961.1 - 0.12 12.5 0.6 0.81 9.8 0.4 2.5 1 1 1 2 2 2 0 IGR protein motif ABC_tran PF00005.27 OAJ25961.1 - 0.31 11.5 0.0 0.31 11.5 0.0 6.3 3 2 0 3 3 3 0 ABC transporter MCC-bdg_PDZ PF10506.9 OAJ25961.1 - 8.3 6.5 17.3 0.16 12.0 0.4 5.1 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CPSase_L_D2 PF02786.17 OAJ25962.1 - 4.7e-114 379.1 0.1 3.2e-82 275.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OAJ25962.1 - 4.3e-48 162.4 0.0 8.6e-48 161.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 OAJ25962.1 - 1e-44 152.1 0.0 2.1e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 OAJ25962.1 - 1.7e-43 148.6 0.0 9.9e-43 146.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OAJ25962.1 - 3.9e-39 133.7 0.0 8.5e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAJ25962.1 - 5.5e-30 104.5 0.0 1.1e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 OAJ25962.1 - 1.1e-17 64.3 0.1 3.8e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAJ25962.1 - 9.4e-16 57.9 0.0 1.6e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 OAJ25962.1 - 5.1e-11 42.6 0.0 1.7e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 OAJ25962.1 - 1e-10 41.5 0.1 2.7e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 OAJ25962.1 - 0.00011 22.0 0.1 0.0067 16.2 0.0 2.7 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 OAJ25962.1 - 0.00019 21.5 0.1 0.93 9.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 OAJ25962.1 - 0.0046 16.8 0.0 0.16 11.7 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Glyoxalase_3 PF13468.6 OAJ25963.1 - 4e-23 82.4 4.6 1.1e-13 51.7 0.0 3.6 3 1 0 3 3 3 2 Glyoxalase-like domain zf-CCHC_6 PF15288.6 OAJ25964.1 - 0.0058 16.4 0.3 0.016 15.0 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle DPBB_1 PF03330.18 OAJ25965.1 - 2.1e-05 24.7 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ25965.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Barwin family PPP4R2 PF09184.11 OAJ25965.1 - 8.2 5.9 16.4 3.9 7.0 4.3 2.2 2 0 0 2 2 2 0 PPP4R2 Sybindin PF04099.12 OAJ25966.1 - 1.4e-39 135.3 0.0 1.5e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAJ25966.1 - 8.9e-07 29.1 0.0 9.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PCNA_N PF00705.18 OAJ25966.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain NRDD PF13597.6 OAJ25966.1 - 0.23 10.2 0.0 0.26 10.0 0.0 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase TIG PF01833.24 OAJ25967.1 - 1.2e-12 47.7 0.7 9.9e-11 41.6 1.3 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 OAJ25967.1 - 9e-10 38.6 0.3 3.6e-09 36.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ25967.1 - 5e-08 33.3 1.1 1.5e-07 31.8 1.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ25967.1 - 3.5e-07 30.7 0.0 7.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ25967.1 - 4.9e-07 29.6 1.1 0.0028 18.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OAJ25967.1 - 2.2e-06 27.9 2.6 0.03 14.8 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Spt20 PF12090.8 OAJ25967.1 - 0.96 9.0 10.3 2.6 7.6 10.3 1.6 1 0 0 1 1 1 0 Spt20 family Adaptin_N PF01602.20 OAJ25974.1 - 8.4e-129 430.5 1.9 1e-128 430.2 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ25974.1 - 7.4e-62 208.2 1.6 5.8e-59 198.8 0.2 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ25974.1 - 4.7e-15 55.7 6.0 4.9e-07 30.1 0.2 4.9 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 OAJ25974.1 - 3.3e-08 33.1 5.7 0.0076 16.4 0.0 5.2 7 0 0 7 7 4 2 HEAT repeat Cnd3 PF12719.7 OAJ25974.1 - 4.9e-07 29.2 0.0 0.00057 19.2 0.0 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OAJ25974.1 - 1.3e-06 28.2 3.0 0.0057 16.6 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ25974.1 - 4.8e-05 23.8 2.1 3.3 8.3 0.1 5.4 6 0 0 6 6 6 1 HEAT-like repeat Arm_2 PF04826.13 OAJ25974.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Armadillo-like RTP1_C1 PF10363.9 OAJ25974.1 - 0.0015 18.7 0.9 0.71 10.1 0.1 3.0 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 OAJ25974.1 - 0.027 14.9 0.3 0.56 10.6 0.0 2.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.8 OAJ25974.1 - 0.19 11.2 3.5 14 5.2 0.1 3.6 4 1 0 4 4 4 0 CLASP N terminal DUF5578 PF17741.1 OAJ25974.1 - 0.39 10.1 3.1 5.7 6.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5578) DUF4202 PF13875.6 OAJ25975.1 - 5.3e-55 186.2 0.0 9.1e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_12 PF08242.12 OAJ25975.1 - 2.9e-15 56.8 0.0 2.7e-13 50.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ25975.1 - 1.3e-13 51.1 0.0 1e-12 48.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ25975.1 - 1e-10 42.2 0.0 5.6e-10 39.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ25975.1 - 1e-08 35.7 0.0 6.1e-07 30.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ25975.1 - 1.2e-06 28.4 0.0 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ25975.1 - 0.0024 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 OAJ25975.1 - 0.0087 17.1 0.0 0.053 14.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain NAM-associated PF14303.6 OAJ25976.1 - 3.6 8.3 17.3 0.22 12.2 11.0 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TFIID-18kDa PF02269.16 OAJ25977.1 - 7.6e-32 109.2 0.5 2.1e-30 104.6 0.7 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Proteasome PF00227.26 OAJ25978.1 - 6.7e-32 110.5 0.0 8.1e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HAMP PF00672.25 OAJ25979.1 - 6e-37 125.8 17.8 2.3e-07 31.1 0.2 9.0 8 2 1 9 9 9 6 HAMP domain HATPase_c PF02518.26 OAJ25979.1 - 4.2e-27 94.9 0.0 1.7e-26 92.9 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ25979.1 - 2.4e-25 88.9 0.7 1.5e-24 86.3 0.5 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAJ25979.1 - 1.9e-16 59.8 0.5 2.6e-15 56.2 0.3 3.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain TMF_TATA_bd PF12325.8 OAJ25979.1 - 0.043 14.0 2.6 9.1 6.5 0.0 4.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3829 PF12889.7 OAJ25979.1 - 0.52 9.8 3.7 8.4 5.8 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3829) DUF3150 PF11348.8 OAJ25979.1 - 1.4 8.1 6.2 1.3 8.2 0.2 3.7 3 1 1 5 5 5 0 Protein of unknown function (DUF3150) FYRC PF05965.14 OAJ25979.1 - 1.7 8.9 3.1 90 3.3 0.0 4.2 5 0 0 5 5 5 0 F/Y rich C-terminus Rab5-bind PF09311.11 OAJ25979.1 - 3.2 7.1 14.2 2 7.7 0.2 4.7 2 2 0 3 3 3 0 Rabaptin-like protein SpoIIID PF12116.8 OAJ25979.1 - 3.8 7.7 4.7 30 4.8 0.0 4.3 6 0 0 6 6 6 0 Stage III sporulation protein D MFS_1 PF07690.16 OAJ25980.1 - 4.8e-06 25.7 2.0 6.1e-06 25.4 2.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DDE_Tnp_4 PF13359.6 OAJ25981.1 - 9.3e-17 61.1 0.0 1.9e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RyR PF02026.16 OAJ25981.1 - 0.0094 16.1 0.3 0.025 14.7 0.3 1.8 1 0 0 1 1 1 1 RyR domain DDE_Tnp_1 PF01609.21 OAJ25981.1 - 0.014 15.1 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Myotub-related PF06602.14 OAJ25981.1 - 0.099 11.6 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Fumble PF03630.14 OAJ25982.1 - 1.4e-121 405.7 0.0 4.3e-121 404.1 0.0 1.7 1 1 0 1 1 1 1 Fumble DUF4407 PF14362.6 OAJ25982.1 - 1.3 8.3 4.8 2.2 7.6 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_pol_phi PF04931.13 OAJ25982.1 - 5.1 5.1 8.4 9.5 4.2 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi B-block_TFIIIC PF04182.12 OAJ25983.1 - 2e-05 24.6 0.0 5.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 OAJ25983.1 - 0.014 15.9 0.0 3.8 8.1 0.0 3.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain PNGaseA PF12222.8 OAJ25984.1 - 1.5e-90 304.2 0.2 3.9e-90 302.8 0.2 1.6 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FAM76 PF16046.5 OAJ25985.1 - 0.11 11.8 0.1 0.11 11.8 0.1 3.3 3 1 1 4 4 4 0 FAM76 protein Sacchrp_dh_C PF16653.5 OAJ25986.1 - 1.7e-82 277.5 0.0 3.1e-82 276.6 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 OAJ25986.1 - 3.6e-63 212.4 0.0 7.5e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 OAJ25986.1 - 1e-23 84.0 1.8 1.1e-23 84.0 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 OAJ25986.1 - 4.1e-20 71.4 0.1 7.2e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain NAD_binding_10 PF13460.6 OAJ25986.1 - 0.00091 19.2 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAJ25986.1 - 0.0023 18.4 0.2 0.0073 16.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ25986.1 - 0.0092 16.7 0.0 0.094 13.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Shikimate_DH PF01488.20 OAJ25986.1 - 0.066 13.3 0.1 0.87 9.6 0.0 2.7 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 OAJ25986.1 - 0.074 13.7 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 OAJ25986.1 - 0.089 13.5 0.2 2.5 8.9 0.1 3.0 2 1 0 2 2 2 0 Methyltransferase domain GFO_IDH_MocA PF01408.22 OAJ25986.1 - 0.2 12.5 1.1 0.34 11.8 0.1 1.9 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold SQS_PSY PF00494.19 OAJ25987.1 - 8.6e-46 156.6 5.8 3.7e-45 154.5 5.8 2.0 1 1 0 1 1 1 1 Squalene/phytoene synthase MFS_1 PF07690.16 OAJ25988.1 - 1.1e-76 258.0 110.7 4.4e-39 134.4 51.3 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAJ25988.1 - 5.7e-21 74.6 57.1 2.4e-11 42.8 23.9 2.1 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ25988.1 - 4.5e-17 62.1 75.7 4.1e-10 39.1 13.4 5.2 3 3 0 5 5 5 4 Sugar (and other) transporter DUF3930 PF13067.6 OAJ25988.1 - 0.0012 19.1 3.6 0.4 11.0 0.4 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3930) MRAP PF15183.6 OAJ25988.1 - 0.0058 16.5 0.7 1.3 9.0 0.0 3.1 2 0 0 2 2 2 1 Melanocortin-2 receptor accessory protein family PsaX PF08078.12 OAJ25988.1 - 0.71 9.9 5.8 5.4 7.1 0.6 2.9 2 0 0 2 2 2 0 PsaX family HCV_NS4a PF01006.20 OAJ25988.1 - 0.97 9.2 12.9 2.6 7.9 1.7 3.4 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a Dak2 PF02734.17 OAJ25988.1 - 3.3 7.6 6.6 25 4.7 0.4 3.5 4 0 0 4 4 4 0 DAK2 domain SirB PF04247.12 OAJ25988.1 - 5.4 7.1 20.2 0.74 9.9 0.3 5.1 6 0 0 6 6 6 0 Invasion gene expression up-regulator, SirB ArAE_2_N PF10337.9 OAJ25989.1 - 8.3e-70 236.1 0.0 3.1e-69 234.3 0.0 1.9 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 OAJ25989.1 - 1.9e-27 96.6 0.0 5.8e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 OAJ25989.1 - 9.3e-09 35.5 18.9 9.3e-09 35.5 18.9 3.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF5408 PF17402.2 OAJ25989.1 - 0.12 12.2 0.5 0.35 10.8 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5408) BSP_II PF05432.11 OAJ25989.1 - 9.9 5.8 6.8 0.3 10.7 0.3 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) 4HBT PF03061.22 OAJ25991.1 - 1.2e-16 60.9 0.5 4e-11 43.1 0.2 3.0 2 1 1 3 3 3 2 Thioesterase superfamily CAP_N PF01213.19 OAJ25991.1 - 2.4 7.6 4.9 4.6 6.6 4.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WES_acyltransf PF03007.16 OAJ25992.1 - 6.6e-16 58.9 0.8 1.4e-15 57.8 0.1 1.9 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 OAJ25992.1 - 9.1e-10 38.7 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) SH3_9 PF14604.6 OAJ25994.1 - 4.4e-08 32.8 0.0 6.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ25994.1 - 9.3e-08 31.6 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ25994.1 - 0.00089 18.9 0.0 0.0023 17.5 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain NUDE_C PF04880.13 OAJ25994.1 - 7.2 7.1 7.1 0.85 10.1 2.5 1.7 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region ASF1_hist_chap PF04729.13 OAJ25996.1 - 4.7e-61 205.3 0.4 1.1e-60 204.0 0.4 1.5 1 1 0 1 1 1 1 ASF1 like histone chaperone NmrA PF05368.13 OAJ25997.1 - 2.4e-24 86.2 0.0 3.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ25997.1 - 1.5e-14 54.3 0.0 4e-14 52.9 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAJ25997.1 - 3.4e-06 27.4 0.0 6.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAJ25997.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAJ25997.1 - 0.027 14.7 0.1 0.1 12.8 0.0 2.0 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_2 PF03446.15 OAJ25997.1 - 0.067 13.4 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IGPS PF00218.21 OAJ25998.1 - 5e-83 278.2 0.0 2.4e-82 275.9 0.0 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 OAJ25998.1 - 4.9e-41 140.6 0.0 8.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 OAJ25998.1 - 2.8e-35 121.9 0.3 1.5e-28 100.0 0.1 3.1 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 OAJ25998.1 - 2.3e-06 27.5 0.3 6.8e-06 26.0 0.3 1.8 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 OAJ25998.1 - 0.029 14.1 1.5 0.06 13.1 0.2 2.2 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain OPA3 PF07047.12 OAJ26000.1 - 2.2e-44 150.3 2.0 4.1e-44 149.3 2.0 1.5 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Histone_HNS PF00816.21 OAJ26000.1 - 0.076 13.8 5.7 0.26 12.1 0.9 2.4 2 0 0 2 2 2 0 H-NS histone family Pyr_redox_2 PF07992.14 OAJ26001.1 - 1.4e-67 228.0 8.2 1.4e-67 228.0 8.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAJ26001.1 - 9.6e-41 138.5 0.1 2.4e-40 137.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAJ26001.1 - 1.7e-20 73.4 12.6 1.7e-18 66.9 2.2 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ26001.1 - 6.7e-12 45.3 5.3 9.4e-09 34.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ26001.1 - 1.3e-11 44.5 0.4 1.3e-11 44.5 0.4 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ26001.1 - 1.7e-09 37.8 4.5 2.4e-05 24.5 0.4 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAJ26001.1 - 1.8e-07 30.6 15.1 3e-07 29.9 5.5 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 OAJ26001.1 - 1.8e-07 30.6 0.6 0.025 13.8 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAJ26001.1 - 2.7e-07 30.0 2.4 2.7e-07 30.0 2.4 3.6 3 1 0 4 4 4 1 FAD binding domain HI0933_like PF03486.14 OAJ26001.1 - 4.3e-06 25.7 14.3 0.00021 20.1 1.1 4.1 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ26001.1 - 1e-05 25.0 7.0 0.0016 17.8 1.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAJ26001.1 - 2.1e-05 23.9 5.1 5.9e-05 22.4 0.2 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAJ26001.1 - 0.00029 20.2 12.1 0.0093 15.2 1.2 3.5 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.19 OAJ26001.1 - 0.041 13.2 0.1 0.17 11.2 0.1 2.0 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.24 OAJ26001.1 - 0.1 12.1 23.3 0.43 10.1 2.5 4.1 2 2 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ26001.1 - 0.7 8.9 5.9 0.42 9.6 0.3 2.7 3 1 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAJ26001.1 - 6.2 7.3 6.8 31 5.1 1.5 3.2 3 1 0 3 3 3 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 OAJ26002.1 - 4.2e-52 177.0 0.2 5.5e-52 176.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ26002.1 - 1.3e-47 161.8 0.3 1.7e-47 161.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ26002.1 - 1.6e-09 38.0 0.2 2e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ26002.1 - 0.02 14.4 0.2 0.044 13.2 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAJ26002.1 - 0.067 12.5 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 OAJ26002.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EMC1_C PF07774.13 OAJ26003.1 - 5.7e-64 215.7 0.0 9.1e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAJ26003.1 - 1e-11 44.9 6.3 0.00016 21.4 0.1 3.9 3 0 0 3 3 3 3 PQQ-like domain PQQ PF01011.21 OAJ26003.1 - 3.6e-07 29.8 0.6 0.0013 18.5 0.1 4.0 3 0 0 3 3 3 2 PQQ enzyme repeat Cas_Cas5d PF09704.10 OAJ26003.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) Cutinase PF01083.22 OAJ26013.1 - 3.5e-18 66.2 0.0 4.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Cutinase PF01083.22 OAJ26014.1 - 3.7e-20 72.6 0.1 4.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.13 OAJ26014.1 - 0.04 13.6 0.1 0.12 12.0 0.1 1.6 1 1 1 2 2 2 0 Serine hydrolase (FSH1) PE-PPE PF08237.11 OAJ26014.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 OAJ26014.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ26014.1 - 0.22 11.0 0.1 0.32 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_S27e PF01667.17 OAJ26015.1 - 2.9e-29 100.5 2.6 3.7e-29 100.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 OAJ26015.1 - 0.13 12.0 2.3 0.25 11.1 2.3 1.5 1 1 0 1 1 1 0 CSL zinc finger zinc_ribbon_12 PF11331.8 OAJ26015.1 - 0.19 11.5 4.4 0.48 10.3 0.3 2.4 1 1 2 3 3 3 0 Probable zinc-ribbon domain Ribosomal_S27e PF01667.17 OAJ26016.1 - 2.9e-29 100.5 2.6 3.7e-29 100.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 OAJ26016.1 - 0.13 12.0 2.3 0.25 11.1 2.3 1.5 1 1 0 1 1 1 0 CSL zinc finger zinc_ribbon_12 PF11331.8 OAJ26016.1 - 0.19 11.5 4.4 0.48 10.3 0.3 2.4 1 1 2 3 3 3 0 Probable zinc-ribbon domain DUF5427 PF10310.9 OAJ26017.1 - 1e-34 120.4 6.6 1.1e-33 116.9 2.7 2.9 1 1 1 2 2 2 1 Family of unknown function (DUF5427) Pardaxin PF07425.11 OAJ26017.1 - 0.069 12.8 1.0 0.22 11.2 1.0 1.8 1 0 0 1 1 1 0 Pardaxin DUF3439 PF11921.8 OAJ26017.1 - 4.9 7.1 10.8 12 5.9 10.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Hist_deacetyl PF00850.19 OAJ26019.1 - 2.2e-83 280.2 0.0 3.1e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SUIM_assoc PF16619.5 OAJ26019.1 - 0.79 9.8 9.7 0.028 14.5 2.4 2.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt_F PF01990.17 OAJ26020.1 - 4.5e-28 97.4 0.1 5.2e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit AA_permease_2 PF13520.6 OAJ26021.1 - 1.9e-80 270.8 38.5 2.3e-80 270.5 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ26021.1 - 2.3e-16 59.5 34.0 4.8e-16 58.4 33.8 1.4 1 1 0 1 1 1 1 Amino acid permease Ribosomal_L19e PF01280.20 OAJ26022.1 - 1.7e-59 200.0 10.5 1.7e-59 200.0 10.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 OAJ26022.1 - 0.0079 15.9 0.2 0.029 14.1 0.2 2.0 1 0 0 1 1 1 1 S4 domain CBS PF00571.28 OAJ26023.1 - 1e-27 96.3 8.3 1.1e-06 29.0 0.1 5.4 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 OAJ26023.1 - 1.7e-06 27.9 0.0 9.8e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 PB1 domain Glyco_hydro_88 PF07470.13 OAJ26024.1 - 1.6e-15 57.0 0.8 2.7e-15 56.3 0.5 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF5329 PF17263.2 OAJ26024.1 - 0.044 14.0 0.8 0.12 12.5 0.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5329) Zn_clus PF00172.18 OAJ26025.1 - 7.2e-08 32.4 28.1 7.3e-06 26.0 8.5 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.21 OAJ26026.1 - 2.6e-41 140.4 0.1 2.9e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP UPF0149 PF03695.13 OAJ26027.1 - 0.056 13.7 0.1 0.074 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) ATP-synt_DE PF00401.20 OAJ26027.1 - 0.094 13.0 2.8 0.14 12.4 2.8 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ATP12 PF07542.11 OAJ26028.1 - 2.8e-38 130.9 0.0 4.4e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein YL1 PF05764.13 OAJ26030.1 - 0.011 15.9 9.4 0.011 15.9 9.4 2.1 2 1 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 OAJ26030.1 - 1.4 7.2 11.6 3.6 5.8 11.6 1.6 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OAJ26030.1 - 2.2 7.0 3.8 3.8 6.3 3.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Clathrin PF00637.20 OAJ26031.1 - 1.9e-162 533.5 27.2 3.9e-31 107.9 0.0 8.1 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 OAJ26031.1 - 5.5e-32 108.5 2.3 7e-06 26.1 0.0 6.6 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 OAJ26031.1 - 6.9e-32 109.2 0.2 1e-30 105.4 0.1 3.0 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 OAJ26031.1 - 0.0004 19.6 7.6 1.4 7.9 0.0 4.8 5 0 0 5 5 5 3 Coatomer WD associated region Rbsn PF11464.8 OAJ26031.1 - 0.012 15.4 0.7 0.56 10.0 0.0 3.6 3 0 0 3 3 3 0 Rabenosyn Rab binding domain TPR_7 PF13176.6 OAJ26031.1 - 0.012 15.5 8.1 44 4.4 0.1 6.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ26031.1 - 0.016 15.3 14.7 8.3 6.8 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26031.1 - 0.41 10.6 14.8 11 6.0 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ26031.1 - 0.72 10.2 8.5 19 5.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ26031.1 - 1.1 10.2 20.6 56 4.9 0.1 9.4 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ26031.1 - 5.9 7.8 6.1 1.1e+02 3.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ26031.1 - 5.9 7.3 8.4 70 3.8 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 OAJ26031.1 - 8.7 6.7 7.5 72 3.7 0.1 4.4 5 0 0 5 5 5 0 MIT domain of nuclear receptor-binding factor 2 AAA PF00004.29 OAJ26032.1 - 7.4e-43 146.1 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ26032.1 - 9.3e-12 44.6 0.1 2.4e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAJ26032.1 - 1.4e-10 41.0 0.1 3.2e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ26032.1 - 2.5e-07 30.8 0.0 3.3e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ26032.1 - 6.7e-07 29.9 0.0 0.00023 21.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ26032.1 - 1.8e-06 28.2 0.0 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAJ26032.1 - 9.7e-06 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ26032.1 - 0.00016 21.9 0.2 0.005 17.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 OAJ26032.1 - 0.00049 20.7 0.0 0.0036 17.9 0.0 2.3 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAJ26032.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAJ26032.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAJ26032.1 - 0.0034 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAJ26032.1 - 0.0043 16.3 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAJ26032.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ26032.1 - 0.0078 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ26032.1 - 0.0081 15.9 0.2 0.044 13.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 OAJ26032.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 OAJ26032.1 - 0.0097 15.6 0.0 0.033 13.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 OAJ26032.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ26032.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAJ26032.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAJ26032.1 - 0.029 14.1 0.5 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ26032.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAJ26032.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ26032.1 - 0.046 13.1 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 OAJ26032.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ26032.1 - 0.069 12.7 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAJ26032.1 - 0.099 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain CPT PF07931.12 OAJ26032.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Phage_tail_APC PF16778.5 OAJ26032.1 - 0.22 11.4 0.5 0.68 9.8 0.1 2.0 2 0 0 2 2 1 0 Phage tail assembly chaperone protein DUF4200 PF13863.6 OAJ26032.1 - 0.49 10.8 3.6 0.21 12.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_23 PF13476.6 OAJ26032.1 - 0.87 10.0 5.2 11 6.5 0.2 2.5 2 1 0 2 2 2 0 AAA domain Complex1_LYR PF05347.15 OAJ26033.1 - 7.5e-10 38.7 5.3 1.4e-09 37.9 5.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ26033.1 - 0.00029 21.5 0.5 0.00046 20.9 0.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like CcmH PF03918.14 OAJ26034.1 - 0.071 12.4 0.1 0.19 11.0 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C biogenesis protein V_ATPase_I PF01496.19 OAJ26034.1 - 0.4 8.5 2.8 0.5 8.2 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vma12 PF11712.8 OAJ26034.1 - 0.47 10.5 5.0 27 4.8 4.5 2.6 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cep57_MT_bd PF06657.13 OAJ26034.1 - 0.62 10.6 12.2 0.37 11.3 1.0 2.8 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DEC-1_N PF04625.13 OAJ26034.1 - 1.5 7.7 7.8 0.085 11.9 0.8 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Mer2 PF09074.10 OAJ26034.1 - 3.3 7.5 8.0 3.6 7.3 6.6 1.6 2 0 0 2 2 2 0 Mer2 Cutinase PF01083.22 OAJ26036.1 - 8.7e-23 81.2 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ26036.1 - 0.0032 17.1 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.12 OAJ26036.1 - 0.021 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 OAJ26036.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAJ26036.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) ECR1_N PF14382.6 OAJ26036.1 - 0.04 13.7 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region LIP PF03583.14 OAJ26036.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Acetyltransf_1 PF00583.25 OAJ26037.1 - 8.2e-13 48.6 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ26037.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ26037.1 - 8e-05 23.0 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ26037.1 - 0.0029 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAJ26037.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAJ26037.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ubiquitin PF00240.23 OAJ26038.1 - 1.4e-101 332.3 14.2 2.3e-33 113.7 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ26038.1 - 7.7e-48 160.2 14.9 1.8e-15 56.5 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ26038.1 - 1.2e-17 64.1 6.8 0.00026 21.4 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ26038.1 - 4.1e-12 45.9 2.5 0.018 15.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ26038.1 - 9.1e-12 45.2 2.6 0.028 14.8 0.1 3.1 1 1 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ26038.1 - 6.2e-11 42.4 1.6 0.078 13.1 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ26038.1 - 4.1e-10 40.2 0.5 0.17 12.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ26038.1 - 1.5e-07 31.4 0.3 0.61 9.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAJ26038.1 - 4.1e-06 26.8 16.7 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 OAJ26038.1 - 5.9e-05 23.2 1.2 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAJ26038.1 - 0.00024 21.4 0.0 20 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 OAJ26038.1 - 0.00032 20.1 0.2 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 OAJ26038.1 - 0.00036 21.2 0.1 22 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain ACT_5 PF13710.6 OAJ26038.1 - 0.0012 18.6 2.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_3_3 PF13750.6 OAJ26038.1 - 0.0019 17.8 0.0 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 OAJ26038.1 - 0.0037 17.9 1.7 0.27 11.9 1.8 2.4 1 1 0 1 1 1 1 Iron Transport-associated domain DUF969 PF06149.12 OAJ26038.1 - 0.0045 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 OAJ26038.1 - 0.0087 16.2 3.5 4.1 7.6 0.1 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase YcgR_2 PF12945.7 OAJ26038.1 - 0.014 15.6 3.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR ACT_4 PF13291.6 OAJ26038.1 - 0.019 15.6 0.3 79 3.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 OAJ26038.1 - 0.023 15.3 0.0 86 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAJ26038.1 - 0.032 13.9 0.1 72 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 OAJ26038.1 - 0.06 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Tash_PEST PF07708.11 OAJ26038.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif ProRS-C_2 PF09181.10 OAJ26038.1 - 0.15 12.2 2.6 78 3.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 OAJ26038.1 - 0.23 11.3 3.4 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 OAJ26038.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 OAJ26038.1 - 0.46 10.4 5.1 62 3.6 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 OAJ26038.1 - 0.56 10.7 5.3 2.5e+02 2.2 5.3 3.1 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 OAJ26038.1 - 2.3 6.8 11.7 13 4.3 0.5 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 OAJ26038.1 - 5.1 6.9 6.0 98 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain SANT_DAMP1_like PF16282.5 OAJ26039.1 - 4.8e-30 103.6 2.2 8e-30 102.9 2.2 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 FHA PF00498.26 OAJ26040.1 - 2.3e-14 53.5 0.1 4.2e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 OAJ26040.1 - 4.8e-11 42.2 12.4 7.6e-11 41.6 12.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAJ26040.1 - 5.7e-07 29.8 13.6 8.4e-07 29.2 13.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ26040.1 - 0.0071 16.2 13.9 0.011 15.5 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ26040.1 - 0.014 15.6 8.9 0.026 14.8 8.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ26040.1 - 0.024 14.7 5.2 0.04 14.0 5.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ26040.1 - 0.044 13.7 13.0 0.067 13.1 13.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ26040.1 - 0.061 13.3 11.8 0.099 12.6 11.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Cwf_Cwc_15 PF04889.12 OAJ26040.1 - 0.24 11.1 12.5 0.57 9.9 12.5 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zn_ribbon_17 PF17120.5 OAJ26040.1 - 1.6 8.4 8.7 2.8 7.6 8.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAJ26040.1 - 2.6 8.0 8.1 4.8 7.2 8.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 OAJ26040.1 - 5.9 7.0 12.8 11 6.2 12.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Vma12 PF11712.8 OAJ26041.1 - 0.68 10.0 2.5 18 5.4 2.0 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Aida_N PF08910.10 OAJ26041.1 - 9.9 6.6 9.2 0.45 10.9 1.2 2.7 3 0 0 3 3 3 0 Aida N-terminus Sec1 PF00995.23 OAJ26042.1 - 1.2e-111 374.8 0.0 1.5e-111 374.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ubiquitin PF00240.23 OAJ26043.1 - 1.4e-101 332.3 14.2 2.3e-33 113.7 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ26043.1 - 7.7e-48 160.2 14.9 1.8e-15 56.5 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ26043.1 - 1.2e-17 64.1 6.8 0.00026 21.4 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ26043.1 - 4.1e-12 45.9 2.5 0.018 15.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ26043.1 - 9.1e-12 45.2 2.6 0.028 14.8 0.1 3.1 1 1 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ26043.1 - 6.2e-11 42.4 1.6 0.078 13.1 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ26043.1 - 4.1e-10 40.2 0.5 0.17 12.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ26043.1 - 1.5e-07 31.4 0.3 0.61 9.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAJ26043.1 - 4.1e-06 26.8 16.7 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 OAJ26043.1 - 5.9e-05 23.2 1.2 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAJ26043.1 - 0.00024 21.4 0.0 20 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 OAJ26043.1 - 0.00032 20.1 0.2 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 OAJ26043.1 - 0.00036 21.2 0.1 22 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain ACT_5 PF13710.6 OAJ26043.1 - 0.0012 18.6 2.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_3_3 PF13750.6 OAJ26043.1 - 0.0019 17.8 0.0 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 OAJ26043.1 - 0.0037 17.9 1.7 0.27 11.9 1.8 2.4 1 1 0 1 1 1 1 Iron Transport-associated domain DUF969 PF06149.12 OAJ26043.1 - 0.0045 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 OAJ26043.1 - 0.0087 16.2 3.5 4.1 7.6 0.1 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase YcgR_2 PF12945.7 OAJ26043.1 - 0.014 15.6 3.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR ACT_4 PF13291.6 OAJ26043.1 - 0.019 15.6 0.3 79 3.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 OAJ26043.1 - 0.023 15.3 0.0 86 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAJ26043.1 - 0.032 13.9 0.1 72 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 OAJ26043.1 - 0.06 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Tash_PEST PF07708.11 OAJ26043.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif ProRS-C_2 PF09181.10 OAJ26043.1 - 0.15 12.2 2.6 78 3.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 OAJ26043.1 - 0.23 11.3 3.4 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 OAJ26043.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 OAJ26043.1 - 0.46 10.4 5.1 62 3.6 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 OAJ26043.1 - 0.56 10.7 5.3 2.5e+02 2.2 5.3 3.1 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 OAJ26043.1 - 2.3 6.8 11.7 13 4.3 0.5 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 OAJ26043.1 - 5.1 6.9 6.0 98 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain eIF_4EBP PF05456.11 OAJ26044.1 - 3.1e-10 40.0 0.9 3.1e-10 40.0 0.9 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Herpes_pp85 PF04637.12 OAJ26044.1 - 1.2 7.5 1.8 2.1 6.7 1.8 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DDE_3 PF13358.6 OAJ26054.1 - 8.1e-27 93.8 0.0 1.7e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ26054.1 - 4.7e-07 30.3 0.7 0.00011 22.8 0.2 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ26054.1 - 3.2e-06 26.7 0.4 9.8e-06 25.1 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 OAJ26054.1 - 0.01 16.0 1.8 0.029 14.6 0.2 2.3 2 0 0 2 2 2 0 Transposase rve PF00665.26 OAJ26054.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.15 OAJ26054.1 - 0.022 14.8 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 OAJ26054.1 - 0.032 14.5 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Transposase RVT_1 PF00078.27 OAJ26055.1 - 7.2e-26 91.1 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNB PF00773.19 OAJ26056.1 - 3.5e-96 322.4 0.0 5.8e-96 321.6 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 OAJ26056.1 - 5.1e-22 78.0 0.2 5.1e-22 78.0 0.2 1.9 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 OAJ26056.1 - 1.2e-21 76.4 0.0 2.7e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OAJ26056.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain UPF0181 PF03701.14 OAJ26061.1 - 0.0092 15.6 1.4 0.012 15.3 0.3 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0181) MatP_C PF17414.2 OAJ26061.1 - 0.082 13.1 0.3 0.29 11.3 0.3 1.9 1 1 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain Ax_dynein_light PF10211.9 OAJ26063.1 - 0.012 15.6 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain EspB_PE PF18625.1 OAJ26065.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Glyco_hydro_52 PF03512.13 OAJ26066.1 - 0.26 10.2 0.6 0.43 9.5 0.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 SLT PF01464.20 OAJ26068.1 - 0.00031 20.4 0.0 0.053 13.2 0.0 2.4 2 0 0 2 2 2 2 Transglycosylase SLT domain IGR PF09597.10 OAJ26071.1 - 3e-09 36.8 0.2 3e-09 36.8 0.2 2.5 3 1 0 3 3 3 1 IGR protein motif Tmemb_cc2 PF10267.9 OAJ26072.1 - 0.033 13.3 0.1 0.037 13.2 0.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-CCHC PF00098.23 OAJ26073.1 - 1.2e-05 25.1 2.2 2.9e-05 23.9 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ26073.1 - 0.00028 20.6 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Copper-fist PF00649.18 OAJ26073.1 - 0.25 10.9 0.7 0.56 9.7 0.7 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain rve PF00665.26 OAJ26075.1 - 6.7e-16 58.6 0.1 1.3e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ26075.1 - 0.0019 17.9 0.1 0.0056 16.4 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 OAJ26076.1 - 7.9e-67 225.4 0.0 1.1e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ26076.1 - 9.8e-18 64.5 0.8 3.5e-16 59.5 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ26076.1 - 2.4e-05 24.1 0.0 7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ26076.1 - 0.0026 17.5 0.4 0.032 14.0 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain PPP4R2 PF09184.11 OAJ26077.1 - 0.016 14.9 5.6 0.027 14.1 5.6 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 OAJ26077.1 - 0.13 11.6 13.8 0.21 10.9 13.8 1.3 1 0 0 1 1 1 0 BUD22 FancD2 PF14631.6 OAJ26077.1 - 0.14 9.5 1.7 0.18 9.2 1.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF4820 PF16091.5 OAJ26077.1 - 0.28 10.5 1.3 0.44 9.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 OAJ26077.1 - 0.34 9.1 11.0 0.41 8.8 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 OAJ26077.1 - 0.37 10.6 6.9 0.64 9.8 6.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 OAJ26077.1 - 0.42 8.8 4.9 0.51 8.6 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 OAJ26077.1 - 1.8 8.4 10.0 3.2 7.7 10.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 OAJ26077.1 - 3.5 7.0 7.9 5.7 6.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 OAJ26077.1 - 4.5 5.3 18.6 6.4 4.8 18.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi ORC_WH_C PF18137.1 OAJ26077.1 - 5 7.2 13.5 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal NOA36 PF06524.12 OAJ26077.1 - 6.8 5.9 11.3 11 5.3 11.3 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 OAJ26077.1 - 7.6 5.4 9.5 13 4.6 9.5 1.3 1 0 0 1 1 1 0 Paf1 NARP1 PF12569.8 OAJ26077.1 - 7.8 5.3 6.7 12 4.7 6.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Transposase_21 PF02992.14 OAJ26082.1 - 2.3e-08 33.5 0.1 1.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ26082.1 - 0.0034 17.0 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Zn_Tnp_IS1595 PF12760.7 OAJ26082.1 - 0.029 14.4 0.6 0.082 12.9 0.6 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain GTP_EFTU PF00009.27 OAJ26083.1 - 9.3e-65 217.8 0.4 1.4e-64 217.2 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAJ26083.1 - 2.5e-31 108.0 0.0 6.1e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAJ26083.1 - 2.7e-21 75.4 0.0 6.1e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAJ26083.1 - 3.2e-13 49.6 0.0 9.5e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAJ26083.1 - 4.9e-12 46.1 0.0 1.5e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ26083.1 - 0.0012 19.0 0.1 0.0025 17.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SH3_9 PF14604.6 OAJ26084.1 - 2.6e-05 24.0 0.3 0.00052 19.8 0.3 2.4 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ26084.1 - 3.9e-05 23.2 0.1 0.00017 21.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain TAF4 PF05236.14 OAJ26084.1 - 0.075 12.8 0.3 0.075 12.8 0.3 3.1 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family Proteasome PF00227.26 OAJ26085.1 - 2.3e-60 203.3 0.0 3.8e-60 202.6 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ26085.1 - 2.5e-09 36.6 0.2 7.6e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Fe-ADH PF00465.19 OAJ26086.1 - 2.8e-94 315.9 0.0 3.7e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ26086.1 - 1.9e-12 47.5 0.0 1.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase GATA PF00320.27 OAJ26087.1 - 1.1e-13 50.5 3.7 2.1e-13 49.6 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 OAJ26087.1 - 5.9e-07 29.5 0.0 5.9e-07 29.5 0.0 3.3 2 1 0 2 2 1 1 PAS fold PAS_3 PF08447.12 OAJ26087.1 - 7.4e-06 26.2 1.1 2e-05 24.8 0.0 2.2 2 0 0 2 2 1 1 PAS fold Neur_chan_memb PF02932.16 OAJ26087.1 - 0.00024 21.3 8.3 0.00043 20.4 8.3 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 OAJ26087.1 - 0.0013 18.8 61.7 0.0024 18.0 61.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4045 PF13254.6 OAJ26087.1 - 0.0089 15.7 17.8 0.02 14.5 17.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) PAS_4 PF08448.10 OAJ26087.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.3 2 1 0 2 2 1 0 PAS fold SAPS PF04499.15 OAJ26087.1 - 0.016 14.0 15.4 0.026 13.3 15.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TF_Zn_Ribbon PF08271.12 OAJ26087.1 - 0.022 14.3 0.4 0.099 12.2 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Presenilin PF01080.17 OAJ26087.1 - 0.051 12.3 33.0 0.076 11.8 33.0 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 OAJ26087.1 - 0.052 13.5 22.3 0.038 13.9 19.5 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF572 PF04502.13 OAJ26087.1 - 0.061 12.9 18.2 0.1 12.2 18.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCSAP PF15748.5 OAJ26087.1 - 0.083 13.0 28.5 0.16 12.1 28.5 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ArfGap PF01412.18 OAJ26087.1 - 0.09 12.9 0.2 0.09 12.9 0.2 2.7 2 1 0 2 2 1 0 Putative GTPase activating protein for Arf Sin_N PF04801.13 OAJ26087.1 - 0.14 11.3 35.9 0.21 10.8 35.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Mem_trans PF03547.18 OAJ26087.1 - 0.15 10.5 0.2 0.17 10.3 0.2 1.1 1 0 0 1 1 1 0 Membrane transport protein PAS_9 PF13426.7 OAJ26087.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 1 0 PAS domain VIR_N PF15912.5 OAJ26087.1 - 0.23 11.0 10.8 0.5 9.9 10.8 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal Ndc1_Nup PF09531.10 OAJ26087.1 - 0.28 9.8 14.8 0.45 9.2 14.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4746 PF15928.5 OAJ26087.1 - 0.35 10.3 19.2 0.57 9.5 19.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 OAJ26087.1 - 0.76 8.9 18.1 1.4 8.0 18.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Dapper PF15268.6 OAJ26087.1 - 1.1 8.0 29.5 1.7 7.4 29.5 1.1 1 0 0 1 1 1 0 Dapper V_ATPase_I PF01496.19 OAJ26087.1 - 1.2 7.0 24.4 2.2 6.1 24.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CRT10 PF08728.10 OAJ26087.1 - 2.5 6.1 12.2 3.4 5.7 12.2 1.1 1 0 0 1 1 1 0 CRT10 Lin-8 PF03353.15 OAJ26087.1 - 3.3 7.2 33.6 5.8 6.4 33.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MCM_bind PF09739.9 OAJ26087.1 - 6 5.2 26.9 8.6 4.7 26.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor UQ_con PF00179.26 OAJ26088.1 - 3.9e-46 156.2 0.0 4.4e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ26088.1 - 6.1e-06 26.0 0.0 7.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ26088.1 - 0.049 13.9 1.7 0.095 13.0 1.7 1.6 1 1 0 1 1 1 0 RWD domain CDC45 PF02724.14 OAJ26090.1 - 0.19 10.0 7.2 0.2 9.9 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 OAJ26090.1 - 0.24 9.7 3.1 0.31 9.3 3.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim17 PF02466.19 OAJ26091.1 - 5.1e-05 23.6 3.6 0.43 11.0 0.0 3.2 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 OAJ26091.1 - 0.013 16.1 0.2 0.054 14.1 0.1 2.1 2 0 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 ADK PF00406.22 OAJ26092.1 - 2.7e-56 189.9 0.1 3.2e-56 189.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ26092.1 - 1.5e-19 70.8 0.3 4.6e-19 69.2 0.1 1.8 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 OAJ26092.1 - 3e-16 59.1 0.0 6.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAJ26092.1 - 0.0025 18.4 0.0 0.0068 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ26092.1 - 0.0041 17.3 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAJ26092.1 - 0.039 13.2 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 OAJ26092.1 - 0.053 13.9 0.1 0.091 13.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UCR_14kD PF02271.16 OAJ26093.1 - 6.2e-38 128.8 0.6 7.3e-38 128.6 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SLC12 PF03522.15 OAJ26095.1 - 0.00054 19.1 0.0 0.00086 18.4 0.0 1.3 1 0 0 1 1 1 1 Solute carrier family 12 Amino_oxidase PF01593.24 OAJ26096.1 - 5.2e-08 32.6 0.1 2.6e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase BicD PF09730.9 OAJ26097.1 - 0.019 13.4 3.1 0.022 13.2 3.1 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.12 OAJ26097.1 - 0.025 14.7 8.0 0.031 14.3 8.0 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein RAP80_UIM PF18282.1 OAJ26097.1 - 0.079 12.7 6.7 0.14 11.9 6.5 1.5 1 1 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif ZapB PF06005.12 OAJ26097.1 - 0.29 11.6 6.4 0.39 11.2 6.4 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF612 PF04747.12 OAJ26097.1 - 0.98 8.5 5.2 1.2 8.2 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Amino_oxidase PF01593.24 OAJ26098.1 - 3.1e-24 86.1 0.6 9.5e-24 84.5 0.6 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ26098.1 - 8.3e-08 32.3 0.1 4.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ26098.1 - 3.6e-06 26.8 0.1 1.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ26098.1 - 0.0011 18.9 0.1 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAJ26098.1 - 0.004 16.1 0.0 0.0083 15.0 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAJ26098.1 - 0.013 14.7 0.0 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ26098.1 - 0.016 14.5 0.0 0.2 10.9 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ26098.1 - 0.035 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF92 PF01940.16 OAJ26099.1 - 7.3e-39 133.6 2.4 8.5e-39 133.4 2.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 p450 PF00067.22 OAJ26101.1 - 3e-29 102.1 0.0 3.1e-23 82.2 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 TF_AP-2 PF03299.14 OAJ26101.1 - 0.11 12.5 0.7 0.67 9.9 0.2 2.4 3 0 0 3 3 3 0 Transcription factor AP-2 GMC_oxred_N PF00732.19 OAJ26102.1 - 6.3e-46 157.1 0.0 8.5e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ26102.1 - 1.2e-27 97.2 0.2 2e-27 96.5 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ26102.1 - 4.2e-05 23.7 0.3 0.00015 21.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ26102.1 - 0.00068 18.8 0.1 0.014 14.5 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ26102.1 - 0.0019 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ26102.1 - 0.0023 17.6 0.2 0.0071 16.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ26102.1 - 0.0038 16.5 0.1 0.01 15.1 0.0 1.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAJ26102.1 - 0.0089 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAJ26102.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 OAJ26102.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAJ26102.1 - 0.085 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein CopB PF05275.11 OAJ26102.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) Lycopene_cycl PF05834.12 OAJ26102.1 - 0.089 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAJ26102.1 - 0.09 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAJ26102.1 - 0.15 12.7 0.0 0.43 11.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 OAJ26102.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A GDI PF00996.18 OAJ26102.1 - 0.27 9.7 0.0 0.49 8.9 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Methyltr_RsmB-F PF01189.17 OAJ26103.1 - 7.2e-30 104.1 0.0 9.9e-20 71.0 0.0 3.6 3 1 0 3 3 3 3 16S rRNA methyltransferase RsmB/F ATP-synt_ab PF00006.25 OAJ26104.1 - 1.2e-71 240.8 0.0 2e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAJ26104.1 - 4.9e-43 146.4 0.5 8.2e-43 145.7 0.5 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAJ26104.1 - 1e-17 64.4 1.7 2.5e-17 63.1 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TniB PF05621.11 OAJ26104.1 - 0.037 13.4 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ICE2 PF08426.10 OAJ26105.1 - 3.2e-52 178.0 0.0 3.3e-49 168.1 0.0 3.2 1 1 0 1 1 1 1 ICE2 ZapB PF06005.12 OAJ26106.1 - 0.0037 17.7 3.4 0.0068 16.8 3.4 1.4 1 0 0 1 1 1 1 Cell division protein ZapB Tropomyosin PF00261.20 OAJ26106.1 - 0.016 14.6 1.0 0.025 13.9 1.0 1.2 1 0 0 1 1 1 0 Tropomyosin HAUS-augmin3 PF14932.6 OAJ26106.1 - 0.026 14.1 1.5 0.033 13.8 0.4 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Rootletin PF15035.6 OAJ26106.1 - 0.082 12.9 0.9 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Sec62 PF03839.16 OAJ26107.1 - 3.8e-50 170.4 1.8 6.7e-50 169.6 1.8 1.4 1 1 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.9 OAJ26107.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) COG6 PF06419.11 OAJ26108.1 - 4.1e-123 411.8 0.0 4.2e-63 213.6 0.0 2.2 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 Carb_kinase PF01256.17 OAJ26109.1 - 7.5e-55 186.1 0.0 9.6e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAJ26109.1 - 0.00039 19.9 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF4516 PF14990.6 OAJ26109.1 - 0.027 14.2 1.2 0.14 11.9 1.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4516) FluMu_N PF17891.1 OAJ26109.1 - 3.4 7.5 4.5 11 5.8 0.1 3.0 2 1 1 3 3 3 0 Mu-like prophage FluMu N-terminal domain SDA1 PF05285.12 OAJ26110.1 - 0.00012 21.7 11.0 0.00021 20.8 11.0 1.4 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 OAJ26110.1 - 8.6 5.7 19.0 17 4.7 19.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF92 PF01940.16 OAJ26111.1 - 7.3e-39 133.6 2.4 8.5e-39 133.4 2.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 RNA_pol_I_TF PF04090.12 OAJ26112.1 - 9e-06 25.3 0.0 8.2e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor PRP21_like_P PF12230.8 OAJ26121.1 - 3.5e-45 154.5 3.5 3.5e-45 154.5 3.5 2.2 1 1 1 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAJ26121.1 - 1.6e-34 117.6 1.0 8.5e-18 64.1 0.1 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 OAJ26121.1 - 0.039 13.6 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 OAJ26121.1 - 0.04 14.6 0.2 0.14 12.8 0.2 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Erg28 PF03694.13 OAJ26122.1 - 2.4e-44 150.2 3.3 2.9e-44 149.9 3.3 1.1 1 0 0 1 1 1 1 Erg28 like protein S1FA PF04689.13 OAJ26122.1 - 0.087 13.0 0.1 9.5 6.4 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA SAC3_GANP PF03399.16 OAJ26123.1 - 8.1e-82 274.9 0.0 1.4e-81 274.1 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family Shadoo PF14999.6 OAJ26123.1 - 3 8.0 8.1 9.6 6.3 8.1 1.9 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Chorismate_bind PF00425.18 OAJ26124.1 - 1.3e-89 300.2 0.1 2.8e-89 299.1 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OAJ26124.1 - 9e-25 87.5 0.0 8.2e-24 84.4 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region adh_short_C2 PF13561.6 OAJ26125.1 - 8.4e-58 195.7 0.2 1.7e-57 194.7 0.2 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ26125.1 - 8.7e-42 142.8 0.3 1.4e-41 142.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ26125.1 - 7.9e-12 45.5 0.1 2.5e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ26125.1 - 0.0004 19.9 0.1 0.0019 17.7 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1687 PF07955.11 OAJ26126.1 - 2.6e-11 44.1 1.9 9.6e-09 35.8 0.1 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1687) CUE PF02845.16 OAJ26127.1 - 0.2 11.4 0.5 29 4.5 0.0 3.4 3 0 0 3 3 3 0 CUE domain DDE_3 PF13358.6 OAJ26128.1 - 1.2e-14 54.2 0.0 2.5e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ26128.1 - 0.00042 20.9 0.1 0.0012 19.4 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ26128.1 - 0.00058 19.4 0.6 0.0011 18.5 0.6 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 OAJ26128.1 - 0.0066 16.7 0.4 0.012 15.8 0.4 1.3 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.16 OAJ26128.1 - 0.021 14.9 0.3 0.036 14.1 0.3 1.3 1 0 0 1 1 1 0 Transposase Toprim_C_rpt PF13368.6 OAJ26128.1 - 0.13 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat UBX PF00789.20 OAJ26129.1 - 3.1e-06 27.3 0.0 6.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 OAJ26129.1 - 7.4e-05 22.9 0.1 0.00026 21.1 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Serglycin PF04360.12 OAJ26129.1 - 1.4 8.9 4.6 20 5.1 0.1 3.2 3 0 0 3 3 3 0 Serglycin SET PF00856.28 OAJ26130.1 - 3.4e-06 27.6 0.0 2.4e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 OAJ26130.1 - 0.089 13.5 0.4 0.48 11.1 0.4 2.1 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding Glyco_hydro_38N PF01074.22 OAJ26131.1 - 1.6e-73 247.6 0.8 2.5e-73 246.9 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAJ26131.1 - 1.2e-47 162.7 0.0 2.4e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAJ26131.1 - 3.1e-26 91.4 0.0 8.1e-26 90.0 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAJ26131.1 - 1.5e-08 34.6 0.0 3.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 OAJ26131.1 - 0.0028 16.9 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 SIS PF01380.22 OAJ26132.1 - 7.5e-14 51.7 0.0 7.8e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 OAJ26132.1 - 0.0015 18.6 0.0 0.032 14.3 0.0 2.3 1 1 1 2 2 2 1 SIS domain RNA_pol_Rpb1_2 PF00623.20 OAJ26132.1 - 0.22 11.7 0.0 0.35 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 MFS_1 PF07690.16 OAJ26133.1 - 4.4e-29 101.5 24.2 4.4e-29 101.5 24.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAJ26133.1 - 0.0046 15.3 2.4 0.0097 14.2 2.4 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family EMP70 PF02990.16 OAJ26133.1 - 0.18 10.4 6.6 0.33 9.6 6.6 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 F-box PF00646.33 OAJ26134.1 - 0.0014 18.4 2.0 0.02 14.7 0.2 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ26134.1 - 0.011 15.6 1.1 0.041 13.8 1.1 2.1 1 0 0 1 1 1 0 F-box-like CSTF2_hinge PF14327.6 OAJ26134.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 SNARE_assoc PF09335.11 OAJ26136.1 - 7.3e-18 65.2 7.0 7.3e-18 65.2 7.0 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4022 PF13214.6 OAJ26136.1 - 0.14 12.4 1.7 0.38 11.0 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) GREB1 PF15782.5 OAJ26136.1 - 1.5 5.8 17.5 2.9 4.9 17.5 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EPL1 PF10513.9 OAJ26136.1 - 5.5 7.3 21.6 9.5 6.6 18.1 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like tRNA-synt_2 PF00152.20 OAJ26137.1 - 3.4e-87 292.5 0.0 3.4e-86 289.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ26137.1 - 3.8e-08 33.2 0.0 6.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 OAJ26137.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Blt1 PF12754.7 OAJ26138.1 - 0.077 13.3 0.4 0.15 12.4 0.4 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain adh_short PF00106.25 OAJ26139.1 - 5.3e-18 65.2 0.1 1.8e-06 27.5 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ26139.1 - 1.5e-13 50.9 0.1 2.4e-10 40.4 0.1 2.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ26139.1 - 3.3e-05 23.9 0.0 6.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAJ26139.1 - 0.061 13.2 0.4 0.73 9.7 0.0 2.2 1 1 1 2 2 2 0 NAD(P)H-binding ubiquitin PF00240.23 OAJ26139.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family MFS_1 PF07690.16 OAJ26140.1 - 0.00025 20.1 3.8 0.00037 19.5 3.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pea-VEAacid PF08111.11 OAJ26141.1 - 0.15 12.4 0.4 0.33 11.4 0.4 1.5 1 0 0 1 1 1 0 Pea-VEAacid family Cellulase PF00150.18 OAJ26142.1 - 7.5e-15 55.1 8.2 2.6e-14 53.3 8.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 OAJ26143.1 - 1.1e-16 61.1 0.1 4.3e-16 59.2 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1554 PF07588.11 OAJ26143.1 - 7.2 6.4 6.6 0.3 10.9 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1554) BRCT PF00533.26 OAJ26144.1 - 1.6e-24 86.1 0.0 3.5e-09 36.9 0.0 4.8 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ26144.1 - 5.1e-21 74.4 0.1 1e-09 38.2 0.0 3.7 4 0 0 4 4 4 2 twin BRCT domain BRCT_2 PF16589.5 OAJ26144.1 - 1.4e-07 31.8 0.0 1.2 9.6 0.0 5.3 5 0 0 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain TIP39 PF14980.6 OAJ26144.1 - 0.12 12.3 0.8 0.35 10.8 0.8 1.7 1 0 0 1 1 1 0 TIP39 peptide Methyltransf_16 PF10294.9 OAJ26145.1 - 9e-16 58.1 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAJ26145.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) VARLMGL PF14383.6 OAJ26145.1 - 0.14 11.7 0.3 0.37 10.4 0.3 1.7 1 0 0 1 1 1 0 DUF761-associated sequence motif DNA_pol_viral_C PF00336.18 OAJ26146.1 - 0.041 13.3 0.1 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Cyclin_N PF00134.23 OAJ26150.1 - 2.3e-13 50.0 0.0 4.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAJ26150.1 - 3.5e-09 37.2 0.0 3.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin DUF3546 PF12066.8 OAJ26151.1 - 6e-17 61.8 2.0 7e-17 61.6 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OAJ26151.1 - 2.5e-07 31.3 0.0 2.5e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Arsenite-resistance protein 2 CNOT11 PF10155.9 OAJ26152.1 - 0.013 15.7 0.0 23 5.2 0.0 3.3 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 DUF4231 PF14015.6 OAJ26152.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DnaJ PF00226.31 OAJ26158.1 - 9.7e-18 64.1 0.2 1.7e-17 63.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3325 PF11804.8 OAJ26158.1 - 0.8 9.9 5.0 0.19 11.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DDHD PF02862.17 OAJ26161.1 - 3.1e-27 96.2 0.0 3.1e-27 96.2 0.0 3.6 3 1 0 3 3 3 1 DDHD domain MIP PF00230.20 OAJ26162.1 - 2.3e-05 24.2 8.8 3.8e-05 23.5 8.8 1.3 1 0 0 1 1 1 1 Major intrinsic protein BAT2_N PF07001.11 OAJ26162.1 - 5.6 7.4 10.1 0.46 10.9 1.3 2.2 2 0 0 2 2 2 0 BAT2 N-terminus F-box-like PF12937.7 OAJ26163.1 - 0.0083 16.0 2.6 0.009 15.9 0.5 2.2 2 0 0 2 2 2 1 F-box-like BCDHK_Adom3 PF10436.9 OAJ26164.1 - 2.6e-40 137.9 0.0 3.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ26164.1 - 2.3e-09 37.7 0.0 4.1e-05 24.1 0.0 2.5 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ26164.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prok-RING_1 PF14446.6 OAJ26165.1 - 0.095 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ING PF12998.7 OAJ26167.1 - 3.2e-11 43.7 0.0 5.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ26167.1 - 1.9e-05 24.4 8.8 3.3e-05 23.7 8.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF4390 PF14334.6 OAJ26167.1 - 0.19 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) zf-C4pol PF14260.6 OAJ26167.1 - 0.22 12.0 5.0 0.26 11.8 1.1 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta MOSC_N PF03476.16 OAJ26168.1 - 2.1e-20 72.8 0.0 3.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAJ26168.1 - 6.5e-20 71.5 0.0 3.8e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 MOSC domain Nop16 PF09420.10 OAJ26169.1 - 3.9e-50 170.8 0.0 4.5e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Nop PF01798.18 OAJ26170.1 - 4.8e-81 271.6 0.2 1e-80 270.6 0.2 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAJ26170.1 - 3.9e-11 43.2 0.0 1.3e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Esterase PF00756.20 OAJ26171.1 - 0.00036 20.3 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase SUR7 PF06687.12 OAJ26172.1 - 0.059 13.0 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 SUR7/PalI family 7tm_7 PF08395.12 OAJ26172.1 - 0.14 11.4 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Oxidored_q2 PF00420.24 OAJ26172.1 - 0.29 10.8 3.0 0.34 10.6 0.9 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Yip1 PF04893.17 OAJ26172.1 - 3.3 7.4 6.9 7.7 6.2 6.9 1.6 1 0 0 1 1 1 0 Yip1 domain Fungal_trans PF04082.18 OAJ26173.1 - 1.9e-27 95.9 0.0 5.6e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ26173.1 - 4.4e-08 33.1 6.1 7.8e-08 32.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_23 PF17931.1 OAJ26173.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DSBA PF01323.20 OAJ26173.1 - 0.087 12.6 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Sof1 PF04158.14 OAJ26174.1 - 3e-26 91.5 12.8 4.7e-26 90.9 12.8 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OAJ26174.1 - 3.2e-25 87.9 4.7 3.8e-05 24.4 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ26174.1 - 2.6e-06 27.6 0.0 3.2 8.1 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AFG1_ATPase PF03969.16 OAJ26175.1 - 1.7e-54 185.1 0.1 6.7e-40 137.1 0.0 4.0 3 1 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.6 OAJ26175.1 - 1.3e-08 35.4 1.4 5.8e-08 33.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ26175.1 - 0.00019 21.5 0.0 0.042 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ26175.1 - 0.0002 21.6 0.0 0.0069 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ26175.1 - 0.0015 19.0 0.0 0.028 14.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAJ26175.1 - 0.0019 18.5 0.0 0.98 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain SR-25 PF10500.9 OAJ26175.1 - 0.0025 17.4 6.9 0.0025 17.4 6.9 2.8 4 0 0 4 4 3 1 Nuclear RNA-splicing-associated protein Mg_chelatase PF01078.21 OAJ26175.1 - 0.0068 15.8 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 OAJ26175.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OAJ26175.1 - 0.086 12.6 0.1 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF4224 PF13986.6 OAJ26175.1 - 0.098 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) TIP49 PF06068.13 OAJ26175.1 - 0.25 10.5 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AF-4 PF05110.13 OAJ26175.1 - 1.4 6.9 9.8 2.1 6.3 9.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3446 PF11928.8 OAJ26175.1 - 4 7.8 26.7 3.2 8.1 12.2 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain Methyltransf_11 PF08241.12 OAJ26176.1 - 1.9e-09 38.1 0.0 3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ26176.1 - 2.7e-08 34.4 0.1 5.1e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ26176.1 - 1.1e-05 25.4 0.0 1.2e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ26176.1 - 0.0014 19.3 0.0 0.0049 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ26176.1 - 0.0041 16.9 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 OAJ26176.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MOR2-PAG1_N PF14222.6 OAJ26178.1 - 8.1e-111 371.6 0.0 1.6e-110 370.7 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAJ26178.1 - 7.6e-74 248.8 3.4 7.6e-74 248.8 3.4 3.1 3 1 1 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAJ26178.1 - 1.7e-19 69.1 1.1 1.6e-07 29.5 0.0 4.6 5 0 0 5 5 5 4 Cell morphogenesis central region RVT_1 PF00078.27 OAJ26179.1 - 2e-26 92.9 0.0 3.3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ26179.1 - 8.7e-17 61.1 0.1 2.7e-16 59.5 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 OAJ26179.1 - 1.8e-10 41.2 0.3 5.4e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.23 OAJ26179.1 - 3.1e-09 36.7 2.1 9.9e-09 35.1 2.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OAJ26179.1 - 0.0041 17.8 0.4 0.0041 17.8 0.4 3.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_3 PF13456.6 OAJ26179.1 - 0.075 12.8 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like zf-CCHC PF00098.23 OAJ26179.1 - 0.68 10.1 3.1 2.3 8.4 3.1 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF4110 PF13422.6 OAJ26179.1 - 0.8 9.8 6.4 0.11 12.5 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) G-patch PF01585.23 OAJ26180.1 - 0.00068 19.5 0.3 0.0032 17.3 0.3 2.2 2 0 0 2 2 2 1 G-patch domain EBV-NA3 PF05009.12 OAJ26180.1 - 0.26 10.8 4.1 8.3 5.9 1.7 2.4 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.12 OAJ26180.1 - 6.1 6.1 7.0 18 4.5 7.0 1.7 1 0 0 1 1 1 0 NOA36 protein SHS2_Rpb7-N PF03876.17 OAJ26182.1 - 4.9e-14 52.4 0.0 8.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAJ26182.1 - 1.1e-13 51.3 0.1 1.6e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OAJ26182.1 - 0.03 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Pex14_N PF04695.13 OAJ26183.1 - 0.045 14.4 7.8 0.072 13.7 0.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RINT1_TIP1 PF04437.13 OAJ26184.1 - 7e-60 203.3 0.0 2.9e-58 198.0 0.0 3.1 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Abhydrolase_6 PF12697.7 OAJ26185.1 - 1.4e-05 25.8 2.0 1.4e-05 25.8 2.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ26185.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 OAJ26185.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 OAJ26185.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_S4e PF00900.20 OAJ26191.1 - 6.5e-35 118.9 0.1 1.4e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAJ26191.1 - 3e-24 84.4 0.6 6.8e-24 83.3 0.1 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAJ26191.1 - 8.9e-20 70.5 5.3 1.8e-19 69.5 5.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 OAJ26191.1 - 0.00025 20.9 1.5 0.00069 19.5 1.5 1.8 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 OAJ26191.1 - 0.00045 19.9 0.2 0.00092 18.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain Sipho_tail PF05709.11 OAJ26191.1 - 0.016 14.7 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Phage tail protein Chitin_synth_1 PF01644.17 OAJ26192.1 - 3.8e-71 238.3 0.0 6.3e-71 237.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ26192.1 - 5.4e-27 93.6 0.0 9.6e-27 92.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ26192.1 - 1.1e-23 83.7 2.5 6.7e-16 58.0 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ26192.1 - 3.8e-08 33.5 7.1 5.7e-08 32.9 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 ABC1 PF03109.16 OAJ26193.1 - 8e-18 64.7 0.1 1e-07 32.1 0.0 2.7 3 0 0 3 3 3 2 ABC1 family Nterm_IS4 PF13006.7 OAJ26193.1 - 0.041 14.1 0.2 0.11 12.7 0.2 1.8 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal CiPC PF15800.5 OAJ26193.1 - 0.21 11.2 2.5 0.4 10.4 2.5 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian Mago-bind PF09282.10 OAJ26194.1 - 9.6e-14 51.0 3.3 9.6e-14 51.0 3.3 2.0 2 0 0 2 2 2 1 Mago binding Hamartin PF04388.12 OAJ26194.1 - 0.4 9.3 5.8 0.47 9.1 5.8 1.1 1 0 0 1 1 1 0 Hamartin protein PBP1_TM PF14812.6 OAJ26194.1 - 0.45 10.9 3.5 1.2 9.6 3.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LAP1C PF05609.12 OAJ26194.1 - 2.1 7.4 6.3 2.6 7.0 6.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NOA36 PF06524.12 OAJ26194.1 - 3.5 6.9 7.1 5.4 6.2 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein SOG2 PF10428.9 OAJ26194.1 - 7.4 5.6 12.3 8.8 5.4 12.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CMAS PF02353.20 OAJ26195.1 - 3.8e-62 210.1 0.1 4.7e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ26195.1 - 8.8e-14 52.0 0.0 2.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ26195.1 - 8.5e-13 48.5 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ26195.1 - 1e-11 45.3 0.0 7e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ26195.1 - 3.2e-06 27.0 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ26195.1 - 6.6e-06 26.8 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAJ26195.1 - 0.00018 21.1 0.0 0.00045 19.8 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.19 OAJ26195.1 - 0.00096 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAJ26195.1 - 0.0052 16.9 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAJ26195.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 OAJ26195.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FA_desaturase PF00487.24 OAJ26196.1 - 3.3e-25 89.4 21.8 5.7e-15 55.8 3.3 2.7 2 1 0 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 OAJ26196.1 - 2.2e-07 30.9 0.0 5.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PQ-loop PF04193.14 OAJ26197.1 - 1.3e-23 82.5 0.6 2.8e-13 49.4 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat Zn_clus PF00172.18 OAJ26198.1 - 8e-05 22.7 11.6 0.00014 21.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 OAJ26198.1 - 0.61 8.3 7.6 0.72 8.1 2.2 2.4 2 0 0 2 2 2 0 CDC45-like protein TFIIA PF03153.13 OAJ26198.1 - 0.69 9.8 25.9 0.095 12.7 14.4 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 OAJ26198.1 - 1.5 8.5 7.8 5.4 6.7 0.7 2.9 2 0 0 2 2 2 0 FAM176 family TPR_2 PF07719.17 OAJ26199.1 - 3e-07 30.0 0.7 1 9.7 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ26199.1 - 0.0055 17.4 11.5 2 9.4 0.8 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ26199.1 - 0.015 16.0 4.5 1 10.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26199.1 - 0.027 14.3 0.7 40 4.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ26199.1 - 0.038 14.2 0.2 76 3.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ26199.1 - 0.089 12.9 1.5 5.8 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ26199.1 - 0.22 12.0 7.4 24 5.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 OAJ26200.1 - 7.4e-24 84.8 0.1 2.7e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain F-actin_cap_A PF01267.17 OAJ26201.1 - 1.4e-69 234.5 0.0 2e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Slx4 PF09494.10 OAJ26203.1 - 6e-08 32.5 0.1 3.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Slx4 endonuclease Mito_carr PF00153.27 OAJ26205.1 - 4.1e-41 138.8 0.7 4.2e-14 52.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PQ-loop PF04193.14 OAJ26206.1 - 1.8e-29 101.3 1.2 1.4e-16 60.0 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OAJ26206.1 - 0.031 15.1 0.8 2.5 8.9 0.3 2.4 1 1 0 2 2 2 0 ER lumen protein retaining receptor PQ-loop PF04193.14 OAJ26207.1 - 3e-24 84.6 5.2 9.5e-17 60.5 0.7 3.5 3 0 0 3 3 3 3 PQ loop repeat DUF3537 PF12056.8 OAJ26207.1 - 0.059 12.2 1.1 0.083 11.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) ER_lumen_recept PF00810.18 OAJ26207.1 - 1.4 9.7 4.4 2.8 8.8 0.4 2.7 3 0 0 3 3 3 0 ER lumen protein retaining receptor Cellulase PF00150.18 OAJ26208.1 - 6.4e-07 29.1 1.7 1.4e-06 28.0 1.7 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 OAJ26209.1 - 4.7e-06 26.2 1.6 8.6e-06 25.4 1.6 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ofd1_CTDD PF10637.9 OAJ26210.1 - 0.17 11.2 1.5 0.38 10.1 1.5 1.5 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term TMEM154 PF15102.6 OAJ26210.1 - 0.21 11.5 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family ANAPC_CDC26 PF10471.9 OAJ26211.1 - 9.5 7.1 15.8 2.3 9.1 10.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 ORMDL PF04061.14 OAJ26212.1 - 3.1e-34 117.7 0.3 3.8e-34 117.4 0.3 1.1 1 0 0 1 1 1 1 ORMDL family TT_ORF2 PF02957.15 OAJ26213.1 - 0.2 12.6 0.2 0.2 12.6 0.2 2.3 1 1 2 3 3 3 0 TT viral ORF2 DDE_Tnp_4 PF13359.6 OAJ26214.1 - 3.4e-34 117.8 0.0 4.6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ26214.1 - 1.5e-06 28.0 0.2 7.8e-05 22.4 0.2 2.3 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ26214.1 - 4.7e-06 26.3 0.0 1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein Asp PF00026.23 OAJ26217.1 - 9.9e-41 140.2 0.0 2.2e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ26217.1 - 1.5e-06 28.6 2.2 0.00072 19.8 0.3 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ26217.1 - 0.025 15.2 0.1 11 6.8 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease Abhydrolase_1 PF00561.20 OAJ26218.1 - 8.9e-30 104.2 0.0 1.7e-29 103.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ26218.1 - 1.3e-11 44.2 0.0 1.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ26218.1 - 2.2e-10 41.5 1.6 2.2e-10 41.5 1.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAJ26218.1 - 0.0087 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Zn_clus PF00172.18 OAJ26219.1 - 0.00013 22.1 10.3 0.00022 21.3 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 OAJ26220.1 - 1.1e-19 70.5 1.0 3e-19 69.2 1.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ26220.1 - 1.2e-11 44.5 0.6 3.1e-11 43.2 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 OAJ26220.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PH PF00169.29 OAJ26221.1 - 7.6e-05 23.2 0.0 0.00049 20.6 0.0 2.3 1 1 0 1 1 1 1 PH domain SOG2 PF10428.9 OAJ26229.1 - 1.4e-90 305.0 6.6 1.4e-90 305.0 6.6 4.1 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 OAJ26229.1 - 8.2e-14 51.1 10.5 2.2e-08 33.8 0.1 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAJ26229.1 - 1.6e-10 41.1 2.3 0.00022 21.6 0.0 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Perilipin PF03036.16 OAJ26229.1 - 0.025 13.6 5.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Perilipin family LRR_1 PF00560.33 OAJ26229.1 - 0.18 12.4 3.2 52 5.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Peptidase_M22 PF00814.25 OAJ26230.1 - 4e-74 249.7 0.0 1.4e-52 179.1 0.1 2.0 2 0 0 2 2 2 2 Glycoprotease family MOZ_SAS PF01853.18 OAJ26231.1 - 1.7e-75 252.7 0.0 2.3e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ26231.1 - 2.4e-20 71.9 2.1 2.4e-20 71.9 2.1 1.7 2 0 0 2 2 2 1 MYST family zinc finger domain Ribosomal_60s PF00428.19 OAJ26231.1 - 0.016 15.8 0.4 0.016 15.8 0.4 3.8 3 1 0 3 3 3 0 60s Acidic ribosomal protein HypA PF01155.19 OAJ26231.1 - 0.043 13.8 0.4 0.083 12.9 0.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Sec23_Sec24 PF04810.15 OAJ26231.1 - 3.2 7.9 6.6 0.38 10.8 0.2 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger VRR_NUC PF08774.11 OAJ26232.1 - 6.8e-22 77.6 0.1 2.4e-21 75.8 0.1 2.0 1 0 0 1 1 1 1 VRR-NUC domain LptE PF04390.12 OAJ26232.1 - 0.12 13.1 0.4 0.41 11.4 0.4 1.9 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Rho_N PF07498.12 OAJ26232.1 - 0.24 11.3 1.0 0.51 10.3 1.0 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Cir_N PF10197.9 OAJ26232.1 - 0.43 10.8 8.4 0.033 14.4 1.7 2.7 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Memo PF01875.17 OAJ26233.1 - 2e-70 237.0 0.0 6.5e-70 235.4 0.0 1.7 1 1 0 1 1 1 1 Memo-like protein ECH_1 PF00378.20 OAJ26234.1 - 1.2e-15 57.5 0.6 3.7e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Formyl_trans_N PF00551.19 OAJ26234.1 - 0.049 13.4 0.0 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Formyl transferase AveC_like PF17198.4 OAJ26235.1 - 0.14 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Spirocyclase AveC-like MIF4G PF02854.19 OAJ26237.1 - 4.2e-52 176.9 0.2 4.6e-29 101.6 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OAJ26237.1 - 1.2e-23 84.3 1.6 4.9e-23 82.4 0.7 2.6 1 1 1 2 2 2 1 Up-frameshift suppressor 2 Pes-10 PF07149.11 OAJ26237.1 - 0.0043 16.2 13.7 0.011 14.9 13.7 1.6 1 0 0 1 1 1 1 Pes-10 Dor1 PF04124.12 OAJ26237.1 - 0.025 13.3 1.4 0.056 12.1 1.4 1.5 1 0 0 1 1 1 0 Dor1-like family CDC45 PF02724.14 OAJ26237.1 - 0.048 12.0 11.0 0.077 11.3 10.3 1.7 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 OAJ26237.1 - 0.49 8.6 27.5 0.052 11.8 22.4 1.9 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ26237.1 - 0.63 8.1 30.1 1.6 6.7 30.1 1.6 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 OAJ26237.1 - 2.3 7.6 23.2 0.012 15.1 14.0 1.8 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.13 OAJ26237.1 - 3.9 7.3 24.5 3.4 7.5 1.0 2.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Zn_clus PF00172.18 OAJ26238.1 - 2.2e-06 27.7 7.2 3.7e-06 27.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.13 OAJ26239.1 - 2.9e-41 142.2 24.7 4.6e-41 141.6 24.7 1.3 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 OAJ26239.1 - 1.9e-09 37.1 0.0 3.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RBD-FIP PF09457.10 OAJ26239.1 - 8.1 6.5 6.3 2.1 8.3 0.8 2.4 2 0 0 2 2 2 0 FIP domain Peptidase_M19 PF01244.21 OAJ26240.1 - 3.6e-95 318.8 0.0 4.2e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) PCMT PF01135.19 OAJ26242.1 - 4.9e-64 215.9 0.0 1.8e-62 210.8 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAJ26242.1 - 0.064 13.0 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ26242.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNA_ligase_A_M PF01068.21 OAJ26243.1 - 6e-18 65.2 0.2 9.5e-08 31.9 0.0 4.2 2 2 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ26243.1 - 2.4e-06 28.0 0.1 7.9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus PIG-H PF10181.9 OAJ26244.1 - 1.4e-08 34.5 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ADH_zinc_N PF00107.26 OAJ26245.1 - 1.7e-16 60.4 1.2 3e-16 59.6 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ26245.1 - 9.3e-10 39.7 0.3 1.8e-09 38.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ26245.1 - 0.0079 16.1 0.0 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DIE2_ALG10 PF04922.12 OAJ26246.1 - 2.2e-121 405.9 6.9 2.2e-93 313.7 8.8 2.0 2 0 0 2 2 2 2 DIE2/ALG10 family LexA_DNA_bind PF01726.16 OAJ26246.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Mito_fiss_reg PF05308.11 OAJ26247.1 - 0.2 11.7 6.6 0.26 11.3 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Nramp PF01566.18 OAJ26248.1 - 1.1e-87 294.3 29.5 5.1e-48 163.9 13.1 3.0 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein DUF1192 PF06698.11 OAJ26249.1 - 0.066 13.3 0.1 0.24 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) SET PF00856.28 OAJ26250.1 - 1e-15 58.5 0.7 3.4e-15 56.8 0.0 2.3 3 0 0 3 3 3 1 SET domain Pre-SET PF05033.16 OAJ26250.1 - 2.5e-14 53.8 9.5 5.2e-14 52.8 6.6 2.3 2 0 0 2 2 2 1 Pre-SET motif preSET_CXC PF18264.1 OAJ26250.1 - 0.016 15.7 7.1 0.016 15.7 7.1 3.4 3 1 0 3 3 3 0 CXC domain Nucleoporin_C PF03177.14 OAJ26251.1 - 2.3e-77 261.2 4.1 3.1e-77 260.7 4.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAJ26251.1 - 3.4e-16 59.0 0.0 6.8e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 Nup133 N terminal like Talin_middle PF09141.10 OAJ26251.1 - 1.1 9.3 5.7 0.13 12.3 0.2 2.2 3 0 0 3 3 3 0 Talin, middle domain Mito_carr PF00153.27 OAJ26252.1 - 2.2e-49 165.3 4.3 2.6e-18 65.7 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ26252.1 - 0.0025 17.0 3.9 0.61 9.2 0.1 3.3 2 1 0 3 3 3 3 Gammaproteobacterial serine protease zf-C2H2 PF00096.26 OAJ26253.1 - 2.6e-20 71.7 22.5 0.0001 22.6 2.5 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ26253.1 - 3.5e-18 65.1 14.2 0.00019 21.7 0.7 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ26253.1 - 4.1e-11 42.7 20.9 0.013 16.3 0.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ26253.1 - 0.00067 20.2 6.8 0.42 11.3 0.1 3.9 2 1 2 4 4 3 2 FOXP coiled-coil domain TFIIA PF03153.13 OAJ26253.1 - 0.00083 19.5 1.7 0.00083 19.5 1.7 4.5 2 1 1 3 3 2 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_jaz PF12171.8 OAJ26253.1 - 0.0093 16.2 5.7 2.9 8.3 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 OAJ26253.1 - 0.11 13.2 6.1 0.06 14.0 0.9 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 OAJ26253.1 - 0.15 12.2 1.5 13 5.9 0.6 2.6 2 1 0 2 2 2 0 Aberrant zinc-finger FYDLN_acid PF09538.10 OAJ26253.1 - 0.49 11.1 11.7 0.17 12.6 6.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.7 OAJ26253.1 - 0.91 10.0 11.8 6 7.4 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Nop14 PF04147.12 OAJ26253.1 - 3.5 5.7 9.4 5.5 5.1 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_6 PF13912.6 OAJ26253.1 - 3.9 7.6 18.0 0.65 10.1 0.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger PPP4R2 PF09184.11 OAJ26253.1 - 5.7 6.4 5.6 15 5.1 5.6 1.6 1 0 0 1 1 1 0 PPP4R2 Chromo PF00385.24 OAJ26255.1 - 1.2e-14 54.0 2.3 1.2e-14 54.0 2.3 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OAJ26255.1 - 1.6e-13 50.5 0.0 2.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain DUF1682 PF07946.14 OAJ26256.1 - 3.6e-62 210.5 0.0 4.2e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3835 PF12927.7 OAJ26257.1 - 1e-05 26.3 10.2 6.3e-05 23.8 0.0 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) Ank_2 PF12796.7 OAJ26258.1 - 1.8e-15 57.2 0.1 2.9e-11 43.8 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ26258.1 - 1e-13 51.5 1.7 1.2e-10 41.7 0.4 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ26258.1 - 4.5e-09 35.8 0.2 0.00062 20.0 0.1 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAJ26258.1 - 6.4e-08 32.7 1.8 0.00011 22.5 0.4 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAJ26258.1 - 3.5e-07 30.4 2.2 0.00024 21.3 0.3 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) TFIIA PF03153.13 OAJ26263.1 - 2.2 8.2 13.1 4.4 7.2 10.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_tranf_2_3 PF13641.6 OAJ26264.1 - 4.2e-30 105.3 0.0 6.2e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ26264.1 - 1.7e-09 37.4 0.1 1.9e-08 33.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ26264.1 - 3.5e-09 36.7 0.0 5.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 OAJ26264.1 - 0.24 11.3 12.8 0.012 15.6 6.4 2.1 2 1 0 2 2 2 0 Glycosyl transferase family group 2 Vps8 PF12816.7 OAJ26265.1 - 9.2e-60 201.6 0.0 1.5e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OAJ26265.1 - 0.015 15.2 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OAJ26265.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Kin17_mid PF10357.9 OAJ26266.1 - 2.2e-45 153.7 0.0 4.2e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 OAJ26266.1 - 0.077 13.3 2.4 0.14 12.5 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAJ26266.1 - 0.15 12.4 1.3 0.23 11.8 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CCDC106 PF15794.5 OAJ26266.1 - 1.7 8.3 8.2 0.43 10.2 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 OAJ26266.1 - 9.3 6.0 15.0 16 5.3 15.0 1.3 1 0 0 1 1 1 0 SPX domain His_Phos_1 PF00300.22 OAJ26268.1 - 1.1e-19 71.0 0.1 3.1e-12 46.6 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) PalH PF08733.10 OAJ26269.1 - 0.00014 21.0 4.3 0.00023 20.3 4.3 1.3 1 0 0 1 1 1 1 PalH/RIM21 TFIIA PF03153.13 OAJ26269.1 - 0.71 9.8 5.8 1.1 9.1 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aft1_HRA PF11786.8 OAJ26269.1 - 1.7 9.1 16.9 0.19 12.1 6.7 2.9 2 1 0 2 2 2 0 Aft1 HRA domain F-box-like PF12937.7 OAJ26270.1 - 8.6e-09 35.2 0.1 8.6e-09 35.2 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ26270.1 - 1.3e-06 28.1 0.7 7.5e-06 25.7 0.0 2.5 3 0 0 3 3 3 1 F-box domain PQQ_2 PF13360.6 OAJ26270.1 - 0.0014 18.3 0.1 0.7 9.4 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OAJ26270.1 - 0.0074 16.2 0.1 3.4 7.8 0.1 2.6 2 0 0 2 2 2 2 PQQ enzyme repeat MutS_V PF00488.21 OAJ26271.1 - 1.8e-80 269.4 0.1 3.1e-80 268.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ26271.1 - 8.5e-37 127.2 2.5 2.3e-36 125.9 0.3 2.4 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAJ26271.1 - 4.5e-19 68.6 0.5 1.6e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 OAJ26271.1 - 2.2e-15 56.8 0.0 8.2e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAJ26271.1 - 2.8e-15 56.8 0.1 9.3e-15 55.1 0.1 2.0 1 0 0 1 1 1 1 MutS domain II DUF2315 PF10231.9 OAJ26272.1 - 1.7e-15 57.2 0.7 5.9e-10 39.3 0.3 2.3 2 0 0 2 2 2 2 Apoptogenic protein 1 SAM_1 PF00536.30 OAJ26273.1 - 0.00099 19.5 0.2 0.0024 18.3 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAJ26273.1 - 0.0091 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Yippee-Mis18 PF03226.14 OAJ26274.1 - 3.4e-11 43.3 0.3 6.5e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Acyl-CoA_dh_2 PF08028.11 OAJ26274.1 - 0.086 13.1 1.4 5.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain MS_channel PF00924.18 OAJ26275.1 - 5.7e-15 55.4 0.5 1.5e-14 54.0 0.5 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAJ26275.1 - 8.4e-05 21.8 0.1 0.00019 20.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAJ26275.1 - 0.0016 18.2 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAJ26275.1 - 0.0036 17.7 0.0 0.0083 16.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Spem1 PF15670.5 OAJ26275.1 - 0.0099 15.5 0.1 0.0099 15.5 0.1 2.7 2 1 0 2 2 2 1 Spermatid maturation protein 1 EF-hand_5 PF13202.6 OAJ26275.1 - 0.051 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 EF hand Zip PF02535.22 OAJ26275.1 - 2.7 7.1 9.4 29 3.7 0.0 2.9 2 0 0 2 2 2 0 ZIP Zinc transporter bZIP_1 PF00170.21 OAJ26276.1 - 0.00066 19.7 20.5 0.0067 16.5 13.1 2.9 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OAJ26276.1 - 1.6 8.9 24.6 0.35 11.0 14.2 3.1 2 0 0 2 2 2 0 Basic region leucine zipper ING PF12998.7 OAJ26277.1 - 7e-07 29.8 0.0 2.8e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ26277.1 - 0.00015 21.6 7.0 0.00025 20.9 7.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ26277.1 - 0.033 13.8 1.7 0.059 12.9 1.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OAJ26277.1 - 0.14 12.5 1.9 0.29 11.4 1.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain MS_channel PF00924.18 OAJ26278.1 - 9.8e-23 80.8 0.0 1.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 OAJ26278.1 - 0.0055 16.5 0.3 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OAJ26278.1 - 0.034 13.7 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 OAJ26278.1 - 0.17 11.4 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 EF hand TFIIA PF03153.13 OAJ26278.1 - 4.8 7.1 28.1 0.16 11.9 16.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RAG1_imp_bd PF12560.8 OAJ26278.1 - 8.7 5.8 10.3 0.086 12.4 2.1 1.8 2 0 0 2 2 2 0 RAG1 importin binding SDA1 PF05285.12 OAJ26279.1 - 1.1e-05 25.0 17.7 2.1e-05 24.1 17.7 1.5 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 OAJ26279.1 - 4 5.5 29.4 8.3 4.5 29.4 1.5 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 OAJ26279.1 - 5.7 6.3 25.1 12 5.2 25.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PI31_Prot_N PF11566.8 OAJ26280.1 - 5.7e-53 179.1 0.0 7.8e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAJ26280.1 - 2.5e-15 57.4 18.2 2.5e-15 57.4 18.2 3.1 3 0 0 3 3 3 1 PI31 proteasome regulator MRI PF15325.6 OAJ26280.1 - 4.5 8.4 6.8 2.1 9.5 0.1 3.0 3 0 0 3 3 3 0 Modulator of retrovirus infection F-box PF00646.33 OAJ26281.1 - 0.0031 17.4 0.0 0.0093 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ26281.1 - 0.019 14.9 0.4 0.051 13.5 0.1 1.9 2 0 0 2 2 2 0 F-box-like SPC12 PF06645.13 OAJ26282.1 - 3.7e-26 91.0 0.2 4.4e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2892 PF11127.8 OAJ26282.1 - 0.0019 18.2 1.1 0.0027 17.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) Aa_trans PF01490.18 OAJ26283.1 - 1.6e-71 241.2 18.9 2.3e-71 240.7 18.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAJ26283.1 - 3.1e-05 23.2 17.5 7e-05 22.0 17.5 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Myb_DNA-bind_7 PF15963.5 OAJ26284.1 - 2.3e-26 91.5 0.2 8.3e-26 89.7 0.2 1.9 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OAJ26284.1 - 6.3e-07 29.5 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TOPRIM_C PF16898.5 OAJ26284.1 - 0.54 10.5 4.3 2.7 8.3 1.4 2.2 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM Rcd1 PF04078.13 OAJ26286.1 - 1.3e-121 404.9 1.1 1.6e-121 404.5 1.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Mog1 PF04603.12 OAJ26287.1 - 2e-39 135.1 0.0 2.4e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein TraA PF05513.11 OAJ26287.1 - 0.16 12.3 0.2 0.27 11.6 0.2 1.4 1 0 0 1 1 1 0 TraA Thioredoxin PF00085.20 OAJ26288.1 - 3.3e-26 91.3 0.0 1.6e-24 85.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OAJ26288.1 - 3.3e-08 33.2 0.0 4.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAJ26288.1 - 0.0054 17.0 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ26288.1 - 0.0071 16.8 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAJ26288.1 - 0.043 13.6 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 OAJ26288.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family NAT PF04768.13 OAJ26289.1 - 7.5e-45 152.6 0.0 1.3e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 OAJ26289.1 - 8.8e-30 104.1 0.0 2.3e-29 102.7 0.0 1.8 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 OAJ26289.1 - 4.5e-22 78.7 0.0 9.8e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Arm PF00514.23 OAJ26289.1 - 0.48 10.6 0.0 0.48 10.6 0.0 3.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat BRCA2 PF00634.18 OAJ26290.1 - 0.4 10.4 2.2 0.83 9.4 2.2 1.5 1 0 0 1 1 1 0 BRCA2 repeat DUF1206 PF06724.11 OAJ26290.1 - 0.53 10.4 4.4 0.74 9.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Acetyltransf_8 PF13523.6 OAJ26291.1 - 1.5e-37 128.5 0.3 2.2e-37 127.9 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1917 PF08939.10 OAJ26292.1 - 1.4e-13 51.3 1.5 3e-13 50.3 0.9 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) Pep1_7 PF17232.2 OAJ26292.1 - 5.4 7.5 13.4 6.3 7.3 0.9 3.5 3 0 0 3 3 3 0 Elicitor peptide 1-7 RMI1_N PF08585.12 OAJ26293.1 - 2.3e-39 135.4 0.1 3.3e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein Ciart PF15673.5 OAJ26293.1 - 0.086 12.2 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor IMPDH PF00478.25 OAJ26294.1 - 2.4e-132 441.2 0.0 1.5e-131 438.5 0.0 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAJ26294.1 - 1.3e-18 67.2 0.0 2.2e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 OAJ26294.1 - 8.9e-11 41.7 3.2 5.7e-08 32.5 2.3 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAJ26294.1 - 6e-10 38.7 1.1 1.2e-09 37.7 0.7 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAJ26294.1 - 1.3e-07 31.4 3.1 3.6e-06 26.6 0.9 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAJ26294.1 - 1.7e-05 24.3 1.9 3e-05 23.5 1.9 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 OAJ26294.1 - 0.046 13.1 0.6 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 OAJ26294.1 - 0.081 12.1 0.1 0.78 8.9 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Dus PF01207.17 OAJ26294.1 - 0.28 10.2 1.5 1.3 8.1 0.2 2.0 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) Phage_integrase PF00589.22 OAJ26298.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family ABC_membrane PF00664.23 OAJ26300.1 - 1.2e-84 284.2 21.1 3.5e-43 148.2 9.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ26300.1 - 1.6e-60 203.6 0.0 1.4e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ26300.1 - 9.5e-11 41.6 0.2 0.0029 17.1 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ26300.1 - 1.4e-07 31.7 1.5 0.0044 16.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ26300.1 - 1.8e-07 31.7 4.4 8.3e-05 23.0 0.1 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ26300.1 - 3.5e-06 26.7 2.1 0.062 13.0 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ26300.1 - 4e-05 24.2 0.0 0.23 12.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAJ26300.1 - 7.8e-05 22.3 0.3 0.52 9.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ26300.1 - 0.00017 21.5 0.3 0.072 13.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 OAJ26300.1 - 0.0016 18.2 0.6 3.6 7.3 0.3 3.5 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ26300.1 - 0.0034 17.4 0.5 2.1 8.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ26300.1 - 0.0041 17.4 5.6 0.78 10.0 1.2 3.9 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OAJ26300.1 - 0.0041 16.9 0.3 5.2 6.8 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_ATPase PF09818.9 OAJ26300.1 - 0.0055 15.6 0.4 1.4 7.6 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 OAJ26300.1 - 0.0071 16.1 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OAJ26300.1 - 0.011 15.1 0.3 1.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 OAJ26300.1 - 0.012 15.7 2.2 1.5 8.9 0.2 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 OAJ26300.1 - 0.015 14.9 0.1 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 OAJ26300.1 - 0.015 15.4 0.0 8.3 6.6 0.0 3.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAJ26300.1 - 0.016 15.7 1.0 2.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OAJ26300.1 - 0.03 13.7 0.7 6.4 6.1 0.0 3.3 4 0 0 4 4 3 0 Bacterial TniB protein G-alpha PF00503.20 OAJ26300.1 - 0.031 13.4 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.26 OAJ26300.1 - 0.038 13.7 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.20 OAJ26300.1 - 0.042 13.7 0.1 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 OAJ26300.1 - 0.061 13.7 0.2 3.9 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAJ26300.1 - 0.15 11.3 0.3 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 OAJ26300.1 - 0.15 11.4 2.4 4.9 6.4 0.2 2.7 3 0 0 3 3 2 0 KaiC NACHT PF05729.12 OAJ26300.1 - 0.18 11.7 1.2 6.2 6.7 0.0 3.5 3 0 0 3 3 2 0 NACHT domain PRK PF00485.18 OAJ26300.1 - 0.24 11.1 0.8 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 OAJ26300.1 - 0.39 10.4 1.1 8.9 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAJ26300.1 - 0.46 10.7 8.3 0.4 10.9 0.3 3.8 4 0 0 4 4 3 0 AAA domain Dynactin_p62 PF05502.13 OAJ26301.1 - 4e-50 171.0 15.4 1.5e-38 132.8 8.5 3.2 3 1 0 3 3 3 2 Dynactin p62 family FAT PF02259.23 OAJ26302.1 - 5.7e-89 298.7 5.8 7.3e-83 278.6 0.1 2.9 2 1 1 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.27 OAJ26302.1 - 6.6e-66 222.7 0.2 1.2e-65 221.8 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAJ26302.1 - 5.2e-48 163.0 0.0 2.9e-43 147.6 0.0 4.0 2 1 1 3 3 3 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAJ26302.1 - 1.3e-23 83.3 0.3 7.1e-23 80.9 0.3 2.4 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OAJ26302.1 - 4.5e-14 52.6 27.9 0.0017 18.7 0.2 11.0 8 3 4 12 12 11 5 HEAT repeats HEAT PF02985.22 OAJ26302.1 - 1.1e-11 43.9 24.1 0.11 12.9 0.2 10.7 12 0 0 12 12 9 4 HEAT repeat FATC PF02260.20 OAJ26302.1 - 2.4e-09 36.9 0.1 6.4e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain UME PF08064.13 OAJ26302.1 - 1.3e-05 25.1 0.1 1.3 9.0 0.0 5.8 5 1 1 6 6 5 1 UME (NUC010) domain Cnd1 PF12717.7 OAJ26302.1 - 3.2e-05 24.0 1.0 1.2 9.2 0.0 4.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 OAJ26302.1 - 0.00013 21.2 0.8 3.6 6.6 0.0 4.3 5 0 0 5 5 5 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAJ26302.1 - 0.00036 21.0 40.6 0.018 15.5 0.2 12.5 12 3 4 16 16 14 5 HEAT-like repeat Ecm29 PF13001.7 OAJ26302.1 - 0.0018 17.0 0.3 0.093 11.4 0.0 2.9 2 0 0 2 2 2 1 Proteasome stabiliser GPP34 PF05719.11 OAJ26302.1 - 0.0036 17.4 0.6 0.015 15.3 0.6 2.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Adaptin_N PF01602.20 OAJ26302.1 - 0.0069 15.0 5.2 1.1 7.7 0.9 4.2 2 1 1 3 3 3 1 Adaptin N terminal region VHS PF00790.19 OAJ26302.1 - 0.03 14.2 0.0 22 4.9 0.0 3.7 4 0 0 4 4 4 0 VHS domain Vac14_Fab1_bd PF12755.7 OAJ26302.1 - 0.037 14.6 0.1 20 5.9 0.0 5.2 6 1 0 6 6 5 0 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 OAJ26302.1 - 0.13 12.2 0.1 0.91 9.4 0.0 2.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF3535 PF12054.8 OAJ26302.1 - 0.13 11.4 1.5 1.9 7.6 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3535) FliL PF03748.14 OAJ26302.1 - 0.19 12.3 0.8 1.7 9.3 0.1 2.9 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL ACPS PF01648.20 OAJ26303.1 - 4.5e-12 46.1 0.3 2.2e-11 43.9 0.3 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily COQ9 PF08511.11 OAJ26304.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 COQ9 zf-met2 PF12907.7 OAJ26305.1 - 1.5e-12 47.4 0.9 2.4e-12 46.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 OAJ26305.1 - 1.9e-08 35.1 10.0 1.9e-08 35.1 10.0 1.6 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_4 PF13894.6 OAJ26305.1 - 0.014 16.2 0.4 0.026 15.3 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger TPT PF03151.16 OAJ26306.1 - 7.6e-23 81.3 17.0 9e-23 81.0 17.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family IMS PF00817.20 OAJ26307.1 - 2e-36 125.3 0.0 4.9e-36 124.0 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ26307.1 - 9.3e-07 29.6 0.0 3e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ26307.1 - 0.04 14.2 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif zf_UBZ PF18439.1 OAJ26307.1 - 0.19 11.3 4.9 2.5 7.8 1.7 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Porphobil_deam PF01379.20 OAJ26308.1 - 3.2e-67 226.0 0.0 1.2e-66 224.2 0.0 1.9 2 1 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAJ26308.1 - 1.2e-12 48.1 0.0 2.6e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain Ribosomal_S2 PF00318.20 OAJ26310.1 - 1.8e-30 105.8 0.1 4e-16 58.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAJ26310.1 - 4.5e-11 44.0 1.9 8.3e-11 43.1 1.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Hepar_II_III PF07940.13 OAJ26311.1 - 2.3e-06 27.4 0.4 4.4e-06 26.5 0.4 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein Avl9 PF09794.9 OAJ26312.1 - 1.1e-127 425.9 0.0 1.4e-127 425.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 OAJ26312.1 - 4.4e-08 33.0 0.0 0.0081 15.8 0.0 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 OAJ26312.1 - 2e-06 27.7 0.0 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 OAJ26312.1 - 0.00061 20.3 0.2 0.0018 18.8 0.2 1.7 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking FAT PF02259.23 OAJ26313.1 - 6.1e-110 367.7 3.0 6.1e-110 367.7 3.0 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAJ26313.1 - 4.5e-64 216.7 0.1 7.1e-64 216.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAJ26313.1 - 1.2e-50 171.6 0.1 3.3e-46 157.1 0.0 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAJ26313.1 - 2.4e-40 136.9 1.1 2.4e-40 136.9 1.1 3.1 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OAJ26313.1 - 1.1e-17 64.2 14.8 0.00037 20.8 0.0 10.0 8 2 1 10 10 10 3 HEAT repeats HEAT PF02985.22 OAJ26313.1 - 1.8e-10 40.2 19.7 3.6 8.1 0.1 11.6 13 0 0 13 13 11 3 HEAT repeat FATC PF02260.20 OAJ26313.1 - 4.1e-09 36.1 0.0 1.1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 OAJ26313.1 - 1.4e-05 25.5 28.8 0.058 13.9 0.0 11.3 11 2 2 14 14 12 3 HEAT-like repeat UME PF08064.13 OAJ26313.1 - 1.5e-05 24.8 0.1 0.27 11.2 0.0 5.2 3 2 2 5 5 5 1 UME (NUC010) domain Cnd1 PF12717.7 OAJ26313.1 - 7.5e-05 22.8 1.3 6.7 6.7 0.0 5.2 4 2 3 7 7 6 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OAJ26313.1 - 0.00044 20.4 4.4 1.3 9.1 0.0 5.4 4 1 1 5 5 5 1 Parkin co-regulated protein Ecm29 PF13001.7 OAJ26313.1 - 0.00092 18.0 1.5 1 8.0 0.0 3.7 4 0 0 4 4 4 2 Proteasome stabiliser DUF3535 PF12054.8 OAJ26313.1 - 0.013 14.8 0.6 1.3 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) Adaptin_N PF01602.20 OAJ26313.1 - 0.039 12.5 6.0 0.21 10.1 0.3 4.4 4 1 1 5 5 5 0 Adaptin N terminal region Nipped-B_C PF12830.7 OAJ26313.1 - 0.057 13.4 0.1 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus TPR_19 PF14559.6 OAJ26313.1 - 0.55 10.8 10.0 33 5.1 0.0 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat Lipase_GDSL PF00657.22 OAJ26314.1 - 4.3e-07 30.1 0.0 5.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAJ26314.1 - 4.5e-05 23.9 0.6 0.00027 21.4 0.6 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GTP_EFTU PF00009.27 OAJ26315.1 - 9.6e-44 149.2 0.0 1.1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ26315.1 - 1.1e-12 48.3 0.0 2.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAJ26315.1 - 1.9e-08 34.4 0.0 9.3e-07 28.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAJ26315.1 - 9.2e-06 26.0 0.1 2.7e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 OAJ26315.1 - 0.00089 18.7 0.0 0.77 9.2 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 OAJ26315.1 - 0.0058 16.5 0.7 0.034 14.0 0.3 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 4 cobW PF02492.19 OAJ26315.1 - 0.032 13.8 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OAJ26315.1 - 0.047 13.0 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 OAJ26315.1 - 0.091 12.3 0.0 6.5 6.3 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ26315.1 - 0.11 12.5 0.0 1 9.4 0.0 2.1 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 OAJ26315.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OAJ26315.1 - 0.19 10.8 0.1 0.57 9.3 0.1 1.6 2 0 0 2 2 2 0 G-protein alpha subunit SMC_N PF02463.19 OAJ26316.1 - 8.8e-61 205.1 0.0 3.4e-60 203.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ26316.1 - 5e-28 97.8 0.2 3.3e-27 95.1 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAJ26316.1 - 4.8e-18 66.0 1.1 3.7e-08 33.6 0.0 3.8 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ26316.1 - 3e-08 33.3 0.2 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ26316.1 - 3e-07 30.5 15.4 3e-07 30.5 15.4 4.4 2 2 0 2 2 1 1 AAA ATPase domain SbcCD_C PF13558.6 OAJ26316.1 - 0.0013 18.9 0.0 0.006 16.8 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.11 OAJ26316.1 - 0.0058 16.9 7.1 0.0058 16.9 7.1 8.2 6 1 2 8 8 7 3 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 OAJ26316.1 - 0.073 13.6 0.0 0.073 13.6 0.0 6.0 4 3 0 4 4 3 0 ABC transporter AAA_23 PF13476.6 OAJ26316.1 - 0.076 13.5 104.9 15 6.0 52.9 6.8 3 2 1 4 4 3 0 AAA domain AAA_22 PF13401.6 OAJ26316.1 - 0.77 10.0 5.4 12 6.2 0.0 4.2 3 1 0 3 3 3 0 AAA domain PKI PF02827.16 OAJ26316.1 - 3.2 8.0 8.2 0.68 10.2 0.5 4.0 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Orthopox_F14 PF06076.12 OAJ26316.1 - 4.5 7.6 5.5 26 5.2 0.1 3.3 3 0 0 3 3 3 0 Orthopoxvirus F14 protein Rhodanese PF00581.20 OAJ26317.1 - 1.5e-15 57.6 0.0 4.4e-08 33.6 0.0 3.4 2 2 1 3 3 3 3 Rhodanese-like domain ThiC-associated PF13667.6 OAJ26317.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain DUF3613 PF12266.8 OAJ26317.1 - 1.4 8.8 6.2 8.6 6.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) HBS1_N PF08938.10 OAJ26318.1 - 8.8e-11 42.0 0.7 2e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 HBS1 N-terminus Cdh1_DBD_1 PF18196.1 OAJ26318.1 - 0.062 13.6 2.1 0.21 11.9 0.1 2.7 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 RNA_pol_Rbc25 PF08292.12 OAJ26320.1 - 1.4e-29 103.0 0.0 3.1e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OAJ26320.1 - 5.9e-16 58.6 0.1 1.1e-15 57.7 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAJ26320.1 - 0.076 13.4 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain Fip1 PF05182.13 OAJ26321.1 - 2.8e-18 65.1 0.6 5.1e-18 64.3 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif DUF3510 PF12022.8 OAJ26322.1 - 1.3e-10 41.8 0.0 7.2e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 OAJ26322.1 - 1.3e-06 28.5 4.4 0.00087 19.4 0.0 2.8 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OAJ26322.1 - 6.4 7.1 5.7 59 4.0 0.5 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Ribosomal_S19e PF01090.19 OAJ26323.1 - 3.1e-53 179.2 0.0 3.6e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Cwf_Cwc_15 PF04889.12 OAJ26323.1 - 0.013 15.2 15.7 0.015 15.1 15.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAJ26323.1 - 0.019 15.3 15.7 0.022 15.0 15.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 OAJ26323.1 - 0.02 14.3 10.7 0.024 14.1 10.7 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 OAJ26323.1 - 0.2 11.7 7.7 0.25 11.4 7.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.13 OAJ26323.1 - 0.75 9.7 11.8 0.77 9.7 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 OAJ26323.1 - 1.7 6.8 12.0 1.9 6.7 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ26323.1 - 2.9 7.2 22.2 3.4 6.9 22.2 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OAJ26323.1 - 3 6.0 14.0 3.1 5.9 14.0 1.0 1 0 0 1 1 1 0 Nop14-like family MIP PF00230.20 OAJ26325.1 - 8.6e-17 61.6 2.2 1e-16 61.4 2.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.6 OAJ26325.1 - 0.022 15.0 2.1 0.052 13.8 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) CitMHS PF03600.16 OAJ26325.1 - 0.062 12.5 1.2 0.064 12.4 1.2 1.1 1 0 0 1 1 1 0 Citrate transporter Gly-zipper_Omp PF13488.6 OAJ26325.1 - 0.26 11.3 3.8 4.2 7.5 0.6 3.0 2 1 0 2 2 2 0 Glycine zipper MgtC PF02308.16 OAJ26325.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.2 2 1 1 3 3 3 0 MgtC family Ribosomal_S7 PF00177.21 OAJ26326.1 - 1.5e-29 102.6 0.1 2.9e-29 101.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Nefa_Nip30_N PF10187.9 OAJ26327.1 - 1.3e-26 93.0 9.4 2e-26 92.4 9.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 TPX2 PF06886.11 OAJ26327.1 - 2.8 8.2 12.9 1.4 9.2 3.5 3.1 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) TFCD_C PF12612.8 OAJ26328.1 - 1e-32 113.5 0.0 1.3e-31 110.0 0.0 2.9 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 OAJ26328.1 - 0.0038 17.4 0.2 3.9 7.7 0.0 4.3 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 OAJ26328.1 - 0.013 14.6 0.1 0.013 14.6 0.1 4.0 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 OAJ26328.1 - 0.014 15.6 0.0 0.014 15.6 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OAJ26328.1 - 0.017 15.7 0.0 0.2 12.2 0.0 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 OAJ26328.1 - 0.032 14.0 0.0 0.2 11.4 0.0 2.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 OAJ26328.1 - 0.035 14.6 0.0 0.035 14.6 0.0 6.5 5 2 2 7 7 7 0 HEAT-like repeat Cnd1 PF12717.7 OAJ26328.1 - 0.037 14.1 0.4 1.1 9.3 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Peptidase_M24 PF00557.24 OAJ26329.1 - 4.6e-13 49.4 0.0 5.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 HLH PF00010.26 OAJ26330.1 - 6.5e-15 54.8 0.3 1e-14 54.2 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SelP_N PF04592.14 OAJ26330.1 - 0.96 8.8 9.0 1.7 8.0 9.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GPP34 PF05719.11 OAJ26331.1 - 4.3e-64 216.3 0.0 5.3e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ribosomal_L27A PF00828.19 OAJ26332.1 - 6.1e-23 81.9 0.1 8.5e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF829 PF05705.14 OAJ26333.1 - 1.4e-24 87.3 0.0 1.6e-15 57.7 0.0 3.5 3 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) DUF4266 PF14086.6 OAJ26333.1 - 0.16 12.9 0.3 0.4 11.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) ECH_1 PF00378.20 OAJ26334.1 - 2.3e-81 272.8 1.6 2.9e-81 272.5 1.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ26334.1 - 4.9e-36 124.9 2.7 3.9e-34 118.7 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAJ26334.1 - 0.00042 20.3 1.2 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 OAJ26334.1 - 0.099 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DnaJ_CXXCXGXG PF00684.19 OAJ26343.1 - 5.6e-14 52.3 10.3 8e-14 51.8 10.3 1.2 1 0 0 1 1 1 1 DnaJ central domain DnaJ_C PF01556.18 OAJ26343.1 - 3.1e-12 46.8 0.0 3.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain HypA PF01155.19 OAJ26343.1 - 0.014 15.4 4.5 0.073 13.1 2.7 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 OAJ26343.1 - 0.075 12.7 0.8 0.075 12.7 0.8 2.0 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Anti-TRAP PF15777.5 OAJ26343.1 - 0.14 12.1 4.3 0.93 9.5 1.9 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 OAJ26343.1 - 0.33 11.1 5.3 2.1 8.5 5.1 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-TFIIB PF13453.6 OAJ26343.1 - 1.8 8.0 8.0 18 4.7 0.2 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger DUF1356 PF07092.12 OAJ26343.1 - 4 6.6 7.9 6.4 6.0 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) DUF5351 PF17302.2 OAJ26343.1 - 7 6.9 14.5 6.2 7.1 1.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5351) DUF1924 PF09086.11 OAJ26343.1 - 8.7 6.8 7.9 3.6 8.0 3.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1924) GCP_N_terminal PF17681.1 OAJ26344.1 - 3.8e-89 299.4 0.0 3.6e-88 296.1 0.0 2.4 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAJ26344.1 - 2.3e-77 260.5 0.3 1.3e-76 258.1 0.1 2.2 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal Pkinase PF00069.25 OAJ26345.1 - 1.8e-45 155.4 0.0 4.6e-44 150.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ26345.1 - 1e-16 61.0 0.0 2.2e-15 56.7 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ26345.1 - 0.0023 16.8 0.0 0.0055 15.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ26345.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ26345.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OAJ26345.1 - 0.059 13.3 0.7 0.17 11.8 0.6 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Med6 PF04934.14 OAJ26346.1 - 8.4e-40 135.6 0.0 1.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component RNA_pol_3_Rpc31 PF11705.8 OAJ26346.1 - 0.00068 20.0 1.2 0.039 14.2 0.6 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 OAJ26346.1 - 0.19 11.6 2.1 0.28 11.0 2.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 OAJ26346.1 - 0.33 10.6 5.2 0.49 10.1 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 OAJ26346.1 - 6.1 7.3 14.3 4.4 7.8 12.4 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rad10 PF03834.14 OAJ26347.1 - 4.3e-49 165.3 0.2 7.1e-49 164.6 0.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAJ26347.1 - 3.8e-07 30.6 0.0 1.4e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 OAJ26347.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif EF1_GNE PF00736.19 OAJ26347.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain Ras PF00071.22 OAJ26348.1 - 6.7e-48 162.3 0.0 7.7e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ26348.1 - 8.1e-18 64.8 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ26348.1 - 2.3e-06 27.1 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ26348.1 - 5.9e-05 23.0 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ26348.1 - 0.00067 19.3 0.1 0.0014 18.2 0.0 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ26348.1 - 0.0016 18.5 0.1 0.0024 17.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 OAJ26348.1 - 0.047 13.2 0.0 0.058 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 OAJ26348.1 - 0.059 12.7 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 AIG1 family AAA_28 PF13521.6 OAJ26348.1 - 0.16 12.2 0.1 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 OAJ26349.1 - 1.5e-21 76.3 5.1 2.3e-21 75.7 5.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ26349.1 - 7.3e-15 55.1 17.0 1.2e-14 54.4 17.0 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ_C PF01556.18 OAJ26349.1 - 5.5e-11 42.8 0.0 9.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain HypA PF01155.19 OAJ26349.1 - 0.0023 17.9 7.7 0.25 11.4 2.9 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 OAJ26349.1 - 0.0028 17.6 6.4 0.24 11.4 0.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein CytoC_RC PF02276.18 OAJ26349.1 - 0.097 12.0 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit TMEM95 PF15203.6 OAJ26349.1 - 1.5 8.4 6.8 4.4 6.9 0.3 2.3 1 1 1 2 2 2 0 TMEM95 family Cytochrom_c3_2 PF14537.6 OAJ26349.1 - 2.3 8.7 12.0 3.3 8.3 4.6 2.3 1 1 1 2 2 2 0 Cytochrome c3 zf-RING_10 PF16685.5 OAJ26349.1 - 2.8 8.1 8.4 5.9 7.1 5.1 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 OAJ26349.1 - 2.8 7.6 11.0 0.23 11.1 0.9 2.6 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 Cytochrome_C7 PF14522.6 OAJ26349.1 - 4.5 7.3 11.6 27 4.9 6.0 2.7 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c NinF PF05810.12 OAJ26349.1 - 8.6 6.3 5.8 3 7.8 0.2 2.3 2 0 0 2 2 2 0 NinF protein Acyl_transf_3 PF01757.22 OAJ26350.1 - 0.00023 20.4 35.0 0.00032 19.9 35.0 1.2 1 0 0 1 1 1 1 Acyltransferase family Phage_holin_5_2 PF16079.5 OAJ26350.1 - 0.028 14.7 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V PCIF1_WW PF12237.8 OAJ26350.1 - 0.098 12.3 0.2 0.26 10.9 0.2 1.7 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain PAS_9 PF13426.7 OAJ26351.1 - 7.6e-21 74.3 0.0 2.4e-13 50.2 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 OAJ26351.1 - 6.7e-13 48.6 0.6 5.5e-08 32.8 0.0 3.9 4 1 0 4 4 4 2 PAS fold PAS_3 PF08447.12 OAJ26351.1 - 8.5e-13 48.4 0.0 1.3e-06 28.6 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 OAJ26351.1 - 1.3e-06 28.6 0.0 0.0003 21.0 0.0 3.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 OAJ26351.1 - 0.00021 21.3 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 OAJ26351.1 - 0.04 14.0 0.1 0.35 11.0 0.0 2.6 3 0 0 3 3 3 0 PAS domain Tad_C PF09977.9 OAJ26351.1 - 0.7 11.2 8.5 6.8 8.0 0.4 3.2 2 0 0 2 2 2 0 Putative Tad-like Flp pilus-assembly TFIIA PF03153.13 OAJ26352.1 - 8.8 6.2 11.7 14 5.5 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Usp PF00582.26 OAJ26353.1 - 1.3e-14 55.0 1.1 6.4e-14 52.7 1.1 2.1 1 1 0 1 1 1 1 Universal stress protein family DUF572 PF04502.13 OAJ26353.1 - 0.37 10.4 8.6 1.4 8.5 8.6 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 OAJ26353.1 - 2.2 7.0 10.8 5.4 5.8 10.8 1.7 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAJ26353.1 - 4.9 5.6 9.6 9.3 4.7 9.6 1.4 1 0 0 1 1 1 0 Macoilin family RNA_ligase PF09414.10 OAJ26354.1 - 3.1e-23 82.9 0.0 5.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 OAJ26354.1 - 2.6e-10 40.6 0.0 1.1e-07 32.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain Y_phosphatase PF00102.27 OAJ26354.1 - 1.8e-06 27.7 0.0 8.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAJ26354.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OAJ26354.1 - 0.0039 17.2 0.5 0.013 15.5 0.5 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family IstB_IS21 PF01695.17 OAJ26354.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAJ26354.1 - 0.035 14.4 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DSPc PF00782.20 OAJ26354.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Zeta_toxin PF06414.12 OAJ26354.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 OAJ26354.1 - 0.11 12.0 0.2 2.2 7.6 0.2 2.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 OAJ26354.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAJ26354.1 - 0.15 12.6 0.0 2.2 8.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ26354.1 - 0.19 12.2 0.0 0.46 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ERAP1_C PF11838.8 OAJ26355.1 - 5.8e-69 233.0 0.2 9.2e-69 232.4 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAJ26355.1 - 7.8e-64 215.2 0.0 1.3e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAJ26355.1 - 4.3e-39 134.6 0.0 1.8e-35 122.8 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Herpes_pp85 PF04637.12 OAJ26356.1 - 0.029 12.8 0.4 0.029 12.8 0.4 1.3 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) NUDE_C PF04880.13 OAJ26356.1 - 0.11 12.9 3.7 0.053 14.0 1.4 1.6 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Nnf1 PF03980.14 OAJ26357.1 - 3e-08 34.0 6.1 3e-08 34.0 6.1 2.2 2 1 0 2 2 2 1 Nnf1 Csm1_N PF18504.1 OAJ26357.1 - 0.037 14.4 1.9 0.037 14.4 1.9 2.7 3 1 0 3 3 3 0 Csm1 N-terminal domain ZapB PF06005.12 OAJ26357.1 - 0.12 12.9 14.9 0.98 9.9 7.6 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 OAJ26357.1 - 1.4 9.5 6.5 0.49 11.0 2.3 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 OAJ26357.1 - 2.4 7.3 5.7 2.7 7.2 3.5 1.9 2 0 0 2 2 2 0 TMPIT-like protein USP8_interact PF08941.10 OAJ26357.1 - 3.4 7.5 8.3 1.1 9.1 3.2 2.4 3 0 0 3 3 3 0 USP8 interacting IFT20 PF14931.6 OAJ26357.1 - 3.6 7.8 10.7 0.3 11.3 4.5 2.5 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 YabA PF06156.13 OAJ26357.1 - 9.5 6.9 9.2 15 6.3 0.0 2.8 2 1 0 2 2 2 0 Initiation control protein YabA Tht1 PF04163.12 OAJ26358.1 - 0.025 13.4 2.8 0.11 11.3 0.0 2.0 1 1 1 2 2 2 0 Tht1-like nuclear fusion protein NusB PF01029.18 OAJ26358.1 - 0.16 12.2 7.2 8.1 6.7 0.2 3.4 2 1 1 3 3 3 0 NusB family GrpE PF01025.19 OAJ26358.1 - 5.5 6.6 11.6 0.16 11.6 1.9 2.3 2 0 0 2 2 2 0 GrpE CAF1 PF04857.20 OAJ26358.1 - 5.5 6.0 7.1 2.9 7.0 5.1 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease Ferric_reduct PF01794.19 OAJ26359.1 - 6.6e-17 61.8 9.7 6.6e-17 61.8 9.7 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ26359.1 - 5.4e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ26359.1 - 3.2e-06 27.2 0.0 0.0001 22.3 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAJ26359.1 - 0.021 15.5 0.0 0.29 11.8 0.0 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAJ26359.1 - 0.028 15.0 8.7 1.7 9.2 1.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) PCRF PF03462.18 OAJ26360.1 - 4e-51 173.6 0.0 1.1e-50 172.3 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OAJ26360.1 - 1.9e-36 124.5 1.6 4.9e-36 123.2 1.6 1.7 1 0 0 1 1 1 1 RF-1 domain DUF2418 PF10332.9 OAJ26361.1 - 1.1e-19 70.8 0.9 1.1e-19 70.8 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) YL1 PF05764.13 OAJ26361.1 - 0.044 13.9 9.5 0.072 13.2 9.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pox_Ag35 PF03286.14 OAJ26361.1 - 0.06 13.1 2.8 0.11 12.3 2.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 OAJ26361.1 - 0.075 12.9 3.2 0.14 12.0 3.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.11 OAJ26361.1 - 0.16 10.8 3.1 0.23 10.3 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 OAJ26361.1 - 0.37 10.4 5.1 0.81 9.3 5.1 1.5 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 OAJ26361.1 - 0.75 10.1 8.5 1.6 9.0 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 OAJ26361.1 - 4.1 6.7 12.7 5.9 6.1 12.7 1.1 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 OAJ26361.1 - 5 6.2 5.9 8.1 5.6 5.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.12 OAJ26361.1 - 5.6 6.6 12.6 0.093 12.4 5.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RasGAP PF00616.19 OAJ26362.1 - 8.2e-59 198.8 0.0 1.6e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAJ26362.1 - 6.7e-40 136.4 0.1 2.2e-39 134.7 0.1 2.0 1 0 0 1 1 1 1 RasGAP C-terminus YabA PF06156.13 OAJ26362.1 - 0.14 12.8 0.4 49 4.6 0.2 3.1 2 0 0 2 2 2 0 Initiation control protein YabA Ribosomal_L19 PF01245.20 OAJ26363.1 - 2.3e-15 56.5 0.1 4.2e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 ABC2_membrane PF01061.24 OAJ26364.1 - 2.6e-33 115.2 17.5 2.6e-33 115.2 17.5 1.8 3 0 0 3 3 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ26364.1 - 4.8e-26 91.9 0.0 7.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ26364.1 - 3.9e-06 26.9 0.6 0.032 14.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ26364.1 - 2.4e-05 24.8 0.3 8.4e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OAJ26364.1 - 0.00021 20.9 0.1 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ26364.1 - 0.001 19.3 0.0 0.0037 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAJ26364.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OAJ26364.1 - 0.0036 17.0 0.2 0.01 15.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ26364.1 - 0.0046 17.5 0.0 0.0089 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ26364.1 - 0.0087 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 OAJ26364.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OAJ26364.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ26364.1 - 0.021 15.3 0.1 0.035 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ26364.1 - 0.024 14.4 0.2 0.046 13.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 OAJ26364.1 - 0.064 13.5 0.1 0.57 10.5 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OAJ26364.1 - 0.07 13.6 0.0 1.1 9.7 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAJ26364.1 - 0.08 13.0 0.1 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAJ26364.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ26364.1 - 0.14 11.9 0.2 2.1 8.0 0.2 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 OAJ26364.1 - 0.24 11.3 0.0 4 7.3 0.1 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 OAJ26364.1 - 0.25 11.4 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 OAJ26365.1 - 1.3e-06 28.4 9.6 1.3e-06 28.4 9.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.10 OAJ26365.1 - 1.1 9.6 17.6 4.2 7.8 17.6 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Proteasome PF00227.26 OAJ26366.1 - 4.5e-46 156.7 0.4 5.1e-43 146.8 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAJ26366.1 - 4.1e-14 51.9 0.1 7.7e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PH_14 PF17787.1 OAJ26366.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 PH domain Ribophorin_II PF05817.14 OAJ26366.1 - 0.028 13.0 0.6 0.033 12.8 0.0 1.4 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II Folate_carrier PF01770.18 OAJ26369.1 - 0.032 13.0 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier FtsX PF02687.21 OAJ26369.1 - 0.11 13.0 2.2 0.23 11.9 2.1 1.5 1 1 0 1 1 1 0 FtsX-like permease family Mic1 PF07035.12 OAJ26370.1 - 0.24 11.1 6.2 1.2 8.8 0.7 2.1 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Gly_radical PF01228.21 OAJ26370.1 - 0.72 10.4 4.8 0.6 10.7 0.9 2.2 2 0 0 2 2 2 0 Glycine radical Keratin_2_head PF16208.5 OAJ26370.1 - 7.9 6.6 16.4 0.7 10.0 9.8 2.1 2 0 0 2 2 2 0 Keratin type II head DUF1768 PF08719.11 OAJ26371.1 - 5.4e-20 72.3 0.0 7.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Not3 PF04065.15 OAJ26372.1 - 4.4e-91 304.4 17.4 4.4e-91 304.4 17.4 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAJ26372.1 - 5.9e-46 155.8 11.4 5.9e-46 155.8 11.4 2.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAJ26372.1 - 0.0026 17.5 3.0 0.008 16.0 3.0 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) XRN_N PF03159.18 OAJ26372.1 - 6.9 6.0 11.7 22 4.4 11.7 1.8 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Mg_trans_NIPA PF05653.14 OAJ26373.1 - 4.7e-07 29.2 0.6 6.2e-07 28.8 0.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Tetraspanin PF00335.20 OAJ26373.1 - 0.033 13.9 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4129 PF13559.6 OAJ26373.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) RNA_pol_Rpc82 PF05645.13 OAJ26383.1 - 5.7e-09 36.1 0.0 4.2e-08 33.3 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 OAJ26383.1 - 7.5e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit QueF_N PF14819.6 OAJ26385.1 - 5.6e-06 26.6 0.5 0.72 10.2 0.1 3.4 3 0 0 3 3 3 3 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term LepB_GAP_C PF18227.1 OAJ26385.1 - 0.0049 17.3 0.0 2.1 9.0 0.0 3.1 1 1 3 4 4 4 2 LepB GAP domain C-terminal subdomain CAP_GLY PF01302.25 OAJ26385.1 - 0.059 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain PNP_UDP_1 PF01048.20 OAJ26386.1 - 1.3e-30 106.5 4.6 1.3e-29 103.1 4.6 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily Guanylate_kin PF00625.21 OAJ26387.1 - 3.4e-54 183.3 0.0 4.1e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 OAJ26387.1 - 5.1e-07 30.2 0.4 1.2e-06 29.0 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ26387.1 - 5.3e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ26387.1 - 3.7e-05 23.7 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 OAJ26387.1 - 0.00034 21.2 0.0 0.00055 20.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 OAJ26387.1 - 0.00038 20.6 0.1 0.00067 19.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ26387.1 - 0.00039 21.0 0.1 0.0011 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ26387.1 - 0.00079 19.2 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OAJ26387.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OAJ26387.1 - 0.0018 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OAJ26387.1 - 0.0023 18.0 0.0 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAJ26387.1 - 0.0049 16.6 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAJ26387.1 - 0.0063 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 OAJ26387.1 - 0.0072 16.3 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NTPase NACHT PF05729.12 OAJ26387.1 - 0.0076 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 OAJ26387.1 - 0.012 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAJ26387.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 OAJ26387.1 - 0.023 14.4 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 OAJ26387.1 - 0.026 14.8 1.2 0.06 13.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OAJ26387.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PTE PF02126.18 OAJ26387.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family Septin PF00735.18 OAJ26387.1 - 0.05 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Septin DUF815 PF05673.13 OAJ26387.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 OAJ26387.1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAJ26387.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ26387.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 OAJ26387.1 - 0.07 13.6 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAJ26387.1 - 0.071 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PTS_IIB PF02302.17 OAJ26387.1 - 0.08 13.6 0.0 0.56 10.9 0.0 2.3 3 0 0 3 3 2 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_19 PF13245.6 OAJ26387.1 - 0.086 13.2 0.0 0.5 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAJ26387.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AFG1_ATPase PF03969.16 OAJ26387.1 - 0.11 11.4 0.0 0.51 9.2 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase cobW PF02492.19 OAJ26387.1 - 0.2 11.3 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SNF2_N PF00176.23 OAJ26388.1 - 3.9e-35 121.2 0.0 1.4e-28 99.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ26388.1 - 6.6e-06 26.4 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CRF PF00473.17 OAJ26388.1 - 0.65 10.1 3.1 21 5.3 0.4 3.7 3 0 0 3 3 3 0 Corticotropin-releasing factor family FUSC_2 PF13515.6 OAJ26389.1 - 5.9e-22 78.1 10.2 5.9e-22 78.1 10.2 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAJ26389.1 - 4.5e-13 48.9 2.2 1.1e-09 37.7 0.4 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 OAJ26389.1 - 1.5e-10 40.3 10.5 2e-10 39.9 1.5 3.0 3 1 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 OAJ26389.1 - 7.9e-09 35.7 0.3 2.2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 OAJ26389.1 - 0.0037 16.4 1.1 0.43 9.6 0.5 2.4 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS EF-1_beta_acid PF10587.9 OAJ26389.1 - 8.1 7.0 7.3 26 5.4 7.3 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Na_H_Exchanger PF00999.21 OAJ26390.1 - 4.6e-56 190.2 10.9 6.2e-56 189.8 10.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAJ26390.1 - 0.003 17.6 2.4 0.021 14.9 0.0 3.0 3 0 0 3 3 3 1 YrhC-like protein 7tm_3 PF00003.22 OAJ26390.1 - 2.7 7.7 10.1 0.077 12.7 2.1 2.2 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DHquinase_I PF01487.15 OAJ26391.1 - 1.1e-36 127.3 0.0 5e-36 125.1 0.0 2.0 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 OAJ26391.1 - 4e-20 72.5 0.0 6.9e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OAJ26391.1 - 0.03 14.9 0.0 0.072 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 OAJ26392.1 - 3.1e-61 201.7 92.7 0.00011 21.9 0.3 21.5 22 0 0 22 22 22 16 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ26392.1 - 6.6e-46 154.5 103.2 2.6e-08 34.1 0.7 18.6 11 5 10 21 21 21 16 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ26392.1 - 1.2e-13 50.0 55.8 1.4 9.3 0.2 19.5 23 0 0 23 23 21 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26392.1 - 3.6e-08 32.9 17.9 4.7 7.2 0.1 14.1 18 0 0 18 18 18 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ26392.1 - 2.3e-07 31.0 40.4 0.096 12.8 0.1 8.7 3 2 5 10 10 10 5 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 OAJ26392.1 - 0.00019 21.4 37.0 22 5.6 0.0 14.9 19 0 0 19 19 17 0 Tetratricopeptide repeat SRC-1 PF08832.10 OAJ26392.1 - 0.016 16.3 0.3 0.048 14.7 0.2 1.9 1 1 0 1 1 1 0 Steroid receptor coactivator Na_Ca_ex_C PF16494.5 OAJ26392.1 - 0.078 13.4 1.8 6.1 7.3 0.1 4.4 3 1 1 4 4 4 0 C-terminal extension of sodium/calcium exchanger domain DUF4007 PF13182.6 OAJ26392.1 - 0.29 10.2 1.8 4.1 6.4 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4007) MIT PF04212.18 OAJ26392.1 - 0.93 9.6 0.0 0.93 9.6 0.0 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 OAJ26392.1 - 1.5 9.1 12.6 7 7.0 1.6 6.0 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 OAJ26392.1 - 3.1 7.3 27.9 0.54 9.7 0.1 9.7 13 0 0 13 13 13 0 SHNi-TPR Wzy_C_2 PF11846.8 OAJ26392.1 - 4.8 7.1 15.0 0.72 9.8 0.5 5.4 5 2 2 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal Imm32 PF15566.6 OAJ26393.1 - 0.32 10.8 1.6 0.84 9.5 1.6 1.6 1 0 0 1 1 1 0 Immunity protein 32 SARAF PF06682.12 OAJ26394.1 - 1.9e-62 211.8 12.0 4.5e-62 210.6 12.0 1.6 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF1768 PF08719.11 OAJ26395.1 - 1.5e-23 83.8 0.0 2.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.25 OAJ26396.1 - 1.9e-54 184.8 0.0 2.9e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ26396.1 - 1.4e-41 142.5 0.0 2.2e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ26396.1 - 2.3e-06 26.7 2.2 2.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAJ26396.1 - 0.018 14.9 1.5 0.12 12.2 0.7 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ26396.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAJ26396.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SK_channel PF03530.14 OAJ26398.1 - 0.38 10.8 8.6 1.2 9.1 3.9 2.8 1 1 1 2 2 2 0 Calcium-activated SK potassium channel Linker_histone PF00538.19 OAJ26399.1 - 6.2e-21 74.6 0.1 6.2e-21 74.6 0.1 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family VIR_N PF15912.5 OAJ26399.1 - 0.57 9.7 12.3 1.1 8.8 12.3 1.4 1 1 0 1 1 1 0 Virilizer, N-terminal ALMT PF11744.8 OAJ26399.1 - 2.4 6.9 4.6 3 6.6 4.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Striatin PF08232.12 OAJ26399.1 - 3 8.4 13.6 13 6.3 8.7 2.1 2 0 0 2 2 2 0 Striatin family Bromodomain PF00439.25 OAJ26400.1 - 1.5e-24 85.9 0.2 2.9e-24 84.9 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OAJ26400.1 - 9e-08 32.4 0.0 2.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ26400.1 - 3.2e-05 23.9 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ26400.1 - 0.00026 21.4 0.2 0.00052 20.4 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_12 PF13424.6 OAJ26401.1 - 0.0065 16.7 0.0 0.034 14.4 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Tim54 PF11711.8 OAJ26401.1 - 0.26 10.0 1.5 0.37 9.5 0.0 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 OAJ26401.1 - 3.8 7.6 6.6 0.22 11.6 0.2 2.1 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) LRR_6 PF13516.6 OAJ26404.1 - 8e-16 56.7 30.9 0.0019 18.1 0.1 10.6 11 0 0 11 11 11 5 Leucine Rich repeat GAT PF03127.14 OAJ26404.1 - 0.00015 22.0 0.1 0.004 17.4 0.1 2.7 2 0 0 2 2 2 1 GAT domain LRR_4 PF12799.7 OAJ26404.1 - 0.0015 18.9 21.4 1.8 9.1 0.2 7.2 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ26404.1 - 0.14 11.9 19.3 19 5.1 0.0 6.5 3 1 3 6 6 6 0 Leucine rich repeat Pinin_SDK_N PF04697.13 OAJ26404.1 - 9.7 6.8 11.9 0.41 11.3 3.7 3.0 2 0 0 2 2 2 0 pinin/SDK conserved region KH_1 PF00013.29 OAJ26405.1 - 9e-06 25.4 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 KH domain HisKA PF00512.25 OAJ26405.1 - 0.043 13.9 0.0 0.062 13.3 0.0 1.3 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HTH_1 PF00126.27 OAJ26405.1 - 0.083 12.9 0.2 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Cofilin_ADF PF00241.20 OAJ26406.1 - 6.8e-39 132.4 0.1 7.6e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GFO_IDH_MocA PF01408.22 OAJ26407.1 - 1.6e-16 61.2 0.0 2.9e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAJ26407.1 - 8.5e-11 41.9 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mito_carr PF00153.27 OAJ26409.1 - 1.2e-53 179.0 0.3 8e-20 70.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CRAL_TRIO_2 PF13716.6 OAJ26410.1 - 6.5e-30 104.1 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 OAJ26410.1 - 1.3e-23 83.5 0.0 2.3e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Paf1 PF03985.13 OAJ26410.1 - 0.24 10.3 8.5 0.4 9.6 8.5 1.2 1 0 0 1 1 1 0 Paf1 Roughex PF06020.11 OAJ26410.1 - 1.4 7.9 5.1 2.7 7.0 5.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SUIM_assoc PF16619.5 OAJ26411.1 - 0.092 12.8 4.4 3.7 7.7 2.8 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Clat_adaptor_s PF01217.20 OAJ26412.1 - 1.2e-53 180.9 1.3 1.3e-53 180.8 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ICMT PF04140.14 OAJ26413.1 - 3.6e-27 94.6 0.2 6.4e-27 93.8 0.2 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ26413.1 - 5.2e-11 42.9 1.7 1.4e-10 41.5 1.7 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAJ26413.1 - 9.8e-05 22.0 0.2 0.00014 21.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAJ26413.1 - 0.0052 15.6 0.2 0.0093 14.8 0.2 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.11 OAJ26413.1 - 0.0062 16.1 1.4 0.0069 15.9 0.2 1.7 2 0 0 2 2 2 1 NnrU protein RRP7 PF12923.7 OAJ26414.1 - 0.023 14.8 0.5 0.044 13.9 0.5 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain FAD_binding_7 PF03441.14 OAJ26415.1 - 1.8e-50 171.3 0.2 2.8e-50 170.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ26415.1 - 3.3e-19 69.5 0.0 1e-18 67.9 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase 7TMR-DISMED2 PF07696.11 OAJ26415.1 - 0.053 13.6 0.3 0.31 11.1 0.1 2.1 1 1 0 2 2 2 0 7TMR-DISM extracellular 2 EMP70 PF02990.16 OAJ26416.1 - 1.1e-182 608.3 0.3 1.4e-182 608.0 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NPBW PF15180.6 OAJ26416.1 - 0.085 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Neuropeptides B and W Inhibitor_Mig-6 PF11555.8 OAJ26416.1 - 0.43 10.7 2.2 21 5.3 0.4 2.7 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Helicase_C_2 PF13307.6 OAJ26421.1 - 1.8e-54 184.5 0.0 4e-54 183.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAJ26421.1 - 8.6e-45 152.5 0.0 2.4e-44 151.0 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 OAJ26421.1 - 0.0025 17.6 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 OAJ26421.1 - 0.0067 15.9 0.1 0.87 9.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Myc_N PF01056.18 OAJ26421.1 - 2.3 8.1 12.0 0.04 13.8 0.6 2.8 3 0 0 3 3 3 0 Myc amino-terminal region eIF-3_zeta PF05091.12 OAJ26422.1 - 1e-178 595.6 0.0 1.9e-167 558.4 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FMN_red PF03358.15 OAJ26423.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 OAJ26423.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin Abhydro_lipase PF04083.16 OAJ26425.1 - 2.7e-15 55.7 0.0 5.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAJ26425.1 - 2.9e-07 30.4 0.1 6.7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ26425.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COX4 PF02936.14 OAJ26426.1 - 1.6e-32 112.4 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV MMR1 PF08505.10 OAJ26427.1 - 1.1 9.5 9.0 2.1 8.6 9.0 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DnaJ PF00226.31 OAJ26428.1 - 2.3e-20 72.5 0.1 5.3e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 OAJ26428.1 - 2.3e-12 46.0 12.9 0.017 15.2 1.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ26428.1 - 2.6e-12 47.0 16.7 0.00056 20.4 0.2 5.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26428.1 - 7.7e-12 44.5 4.5 0.0008 19.1 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ26428.1 - 1.3e-11 44.0 2.3 0.0041 17.4 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ26428.1 - 5.4e-11 42.5 14.6 1.1e-05 25.4 0.7 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ26428.1 - 1.3e-09 38.5 29.7 5.4e-05 23.8 0.6 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ26428.1 - 4e-09 36.5 21.2 0.016 15.9 2.9 6.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ26428.1 - 3.8e-07 29.8 2.8 4.7 7.7 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ26428.1 - 4.8e-06 26.2 5.4 0.0014 18.3 0.2 4.1 3 1 1 4 4 3 1 TPR repeat ANAPC3 PF12895.7 OAJ26428.1 - 0.0014 18.8 6.0 1 9.7 0.1 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 OAJ26428.1 - 0.0065 16.8 9.3 1 9.8 0.1 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat PknG_TPR PF16918.5 OAJ26428.1 - 0.027 13.2 9.0 0.02 13.6 3.6 2.8 2 1 1 3 3 3 0 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 OAJ26428.1 - 0.042 14.3 1.1 0.042 14.3 1.1 4.1 2 1 2 5 5 5 0 Bacterial transcriptional activator domain CYLD_phos_site PF16607.5 OAJ26428.1 - 0.087 12.7 3.0 0.071 13.0 0.7 1.9 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured RPT PF13446.6 OAJ26428.1 - 0.11 12.5 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein TPR_12 PF13424.6 OAJ26428.1 - 0.24 11.7 14.5 4.7 7.6 0.3 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ26428.1 - 0.4 10.8 5.8 11 6.3 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 OAJ26428.1 - 0.57 8.9 4.0 3.5 6.3 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.6 OAJ26428.1 - 0.79 9.8 5.6 4.7 7.4 0.2 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Pex19 PF04614.12 OAJ26428.1 - 2.7 7.7 9.4 1.1 8.9 4.0 2.1 2 0 0 2 2 2 0 Pex19 protein family TPR_6 PF13174.6 OAJ26428.1 - 3.5 8.5 16.2 18 6.2 0.0 7.2 8 1 0 8 8 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAJ26428.1 - 6.8 7.2 9.1 20 5.6 0.2 3.6 3 1 0 4 4 4 0 Alkyl sulfatase dimerisation Rad17 PF03215.15 OAJ26429.1 - 5.5e-17 62.3 0.0 9.9e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 OAJ26429.1 - 0.0004 20.7 0.0 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ26429.1 - 0.00064 20.1 0.6 0.003 17.9 0.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OAJ26429.1 - 0.016 15.7 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 OAJ26429.1 - 0.021 14.8 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 OAJ26429.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 OAJ26429.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA PF00004.29 OAJ26429.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAJ26429.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain 4_1_CTD PF05902.13 OAJ26429.1 - 4.4 7.4 6.4 0.6 10.2 2.0 1.8 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) Ribosomal_L1 PF00687.21 OAJ26430.1 - 6.7e-48 163.1 0.0 1.3e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RXT2_N PF08595.11 OAJ26430.1 - 8.1 6.5 10.4 20 5.1 10.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.11 OAJ26430.1 - 9.5 5.7 18.1 0.24 10.9 9.7 2.0 2 0 0 2 2 2 0 PPP4R2 Phosphodiest PF01663.22 OAJ26431.1 - 1.4e-57 195.9 0.2 2.9e-55 188.3 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAJ26431.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Spt5_N PF11942.8 OAJ26431.1 - 0.92 10.5 8.6 0.42 11.6 2.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic PF14632.6 OAJ26431.1 - 1.7 9.3 11.4 0.21 12.2 5.5 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Snf7 PF03357.21 OAJ26432.1 - 8.6e-19 67.8 7.3 1.2e-18 67.3 7.3 1.2 1 0 0 1 1 1 1 Snf7 CAP_GLY PF01302.25 OAJ26433.1 - 4.3e-14 52.3 0.4 7.6e-14 51.5 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_4 PF14392.6 OAJ26433.1 - 0.0034 17.1 3.7 0.076 12.8 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle DUF3087 PF11286.8 OAJ26433.1 - 0.62 9.5 2.9 1.4 8.4 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF1943 PF09172.11 OAJ26433.1 - 2.1 7.5 9.1 0.7 9.1 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DEAD PF00270.29 OAJ26434.1 - 2.7e-31 108.7 0.0 8.3e-31 107.1 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26434.1 - 8.3e-25 87.3 0.0 2.2e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAJ26434.1 - 0.017 13.9 0.0 1.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ORC4_C PF14629.6 OAJ26435.1 - 1e-26 93.7 0.0 2.7e-26 92.3 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAJ26435.1 - 1.7e-07 31.7 0.3 4.7e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain YL1 PF05764.13 OAJ26435.1 - 0.0047 17.1 6.0 0.0047 17.1 6.0 2.4 2 1 0 2 2 2 1 YL1 nuclear protein DUF815 PF05673.13 OAJ26435.1 - 0.0066 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Apt1 PF10351.9 OAJ26435.1 - 0.069 12.0 1.1 0.3 9.9 1.2 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain CDC45 PF02724.14 OAJ26435.1 - 1.9 6.7 14.3 0.25 9.6 5.8 2.2 2 0 0 2 2 2 0 CDC45-like protein HOOK PF05622.12 OAJ26436.1 - 7.5e-50 169.8 69.0 7.5e-50 169.8 69.0 3.2 1 1 1 2 2 2 1 HOOK protein BLOC1_2 PF10046.9 OAJ26436.1 - 0.0027 17.9 9.4 0.0027 17.9 9.4 6.7 5 2 2 7 7 7 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 OAJ26436.1 - 0.24 10.9 89.8 0.02 14.5 11.9 5.1 3 2 1 5 5 5 0 Intermediate filament protein Lactamase_B_2 PF12706.7 OAJ26438.1 - 4.9e-05 22.9 4.3 0.00015 21.3 1.6 2.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAJ26438.1 - 0.04 13.9 0.4 0.14 12.2 0.4 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PLDc PF00614.22 OAJ26440.1 - 1e-15 57.1 0.2 7.5e-07 29.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAJ26440.1 - 2.2e-12 47.0 0.0 1.1e-06 28.6 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OAJ26440.1 - 6.6e-09 35.7 0.0 1.9e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.29 OAJ26440.1 - 0.083 13.4 0.1 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 PH domain Thioredoxin PF00085.20 OAJ26441.1 - 8.7e-05 22.5 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3417 PF11897.8 OAJ26441.1 - 0.019 15.4 0.4 0.032 14.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DIM1 PF02966.16 OAJ26441.1 - 0.1 12.4 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Ank_2 PF12796.7 OAJ26444.1 - 1.4e-07 32.0 0.1 2.3e-06 28.1 0.1 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ26444.1 - 4.7e-07 30.2 0.0 0.00034 21.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ26444.1 - 0.0003 21.1 0.1 2.4 8.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAJ26444.1 - 0.00044 20.5 0.0 25 5.9 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OAJ26444.1 - 0.0012 19.1 0.0 3.3 8.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) FAM76 PF16046.5 OAJ26445.1 - 1.1 8.5 10.1 3.5 6.9 10.1 1.7 1 0 0 1 1 1 0 FAM76 protein SLC12 PF03522.15 OAJ26445.1 - 8.4 5.3 8.7 19 4.1 8.7 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Ribosomal_L7Ae PF01248.26 OAJ26446.1 - 6.1e-26 90.0 0.1 7.8e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAJ26446.1 - 0.0009 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 OAJ26446.1 - 0.004 17.2 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Paf67 PF10255.9 OAJ26447.1 - 4.2e-168 559.5 0.0 7e-168 558.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 OAJ26447.1 - 0.0063 16.5 0.0 0.0063 16.5 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26447.1 - 0.0083 15.9 0.0 0.068 13.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SNF2_N PF00176.23 OAJ26448.1 - 4.3e-57 193.4 0.0 3.8e-56 190.3 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ26448.1 - 2.3e-15 56.9 0.0 8.7e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ26448.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 OAJ26448.1 - 2e-07 30.8 3.6 2e-07 30.8 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ26448.1 - 3.1e-06 27.2 5.6 3.1e-06 27.2 5.6 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAJ26448.1 - 4e-06 26.6 3.8 4e-06 26.6 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ26448.1 - 3.9e-05 23.4 4.3 3.9e-05 23.4 4.3 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAJ26448.1 - 4.2e-05 23.3 5.0 4.2e-05 23.3 5.0 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ26448.1 - 0.0001 22.3 1.9 0.0001 22.3 1.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ26448.1 - 0.00038 20.7 6.1 0.00038 20.7 6.1 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OAJ26448.1 - 0.00074 19.4 5.6 0.00074 19.4 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAJ26448.1 - 0.04 13.8 4.0 0.083 12.8 4.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OAJ26448.1 - 0.14 12.3 4.6 0.66 10.1 4.6 2.1 1 1 0 1 1 1 0 zinc RING finger of MSL2 Zn_Tnp_IS91 PF14319.6 OAJ26448.1 - 2.9 8.0 12.6 3.7 7.6 1.3 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain BCAS2 PF05700.11 OAJ26449.1 - 9.6e-40 136.5 4.2 1.1e-39 136.3 4.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CASP_C PF08172.12 OAJ26449.1 - 0.00024 20.5 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 CASP C terminal T2SSE_N PF05157.15 OAJ26449.1 - 0.0082 16.4 0.2 0.12 12.7 0.1 2.5 1 1 2 3 3 3 1 Type II secretion system (T2SS), protein E, N-terminal domain HtaA PF04213.13 OAJ26449.1 - 0.1 13.1 0.2 0.16 12.4 0.2 1.3 1 0 0 1 1 1 0 Htaa Band_7 PF01145.25 OAJ26454.1 - 2.9e-11 43.7 0.0 2.9e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family MTABC_N PF16185.5 OAJ26455.1 - 0.42 10.1 4.3 0.95 8.9 4.3 1.6 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region TcpE PF12648.7 OAJ26455.1 - 0.83 10.2 3.7 0.93 10.1 0.6 2.4 2 1 0 2 2 2 0 TcpE family DUF4017 PF13209.6 OAJ26455.1 - 0.94 9.5 5.0 0.31 11.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) DUF3087 PF11286.8 OAJ26455.1 - 6.8 6.1 6.4 0.77 9.2 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Carn_acyltransf PF00755.20 OAJ26457.1 - 1.5e-188 628.1 0.0 1.7e-188 627.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_25 PF13481.6 OAJ26458.1 - 0.037 13.6 0.2 3.6 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 OAJ26458.1 - 0.073 12.4 0.0 6.4 6.0 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Sgf11 PF08209.11 OAJ26458.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) DnaJ-X PF14308.6 OAJ26460.1 - 5.3e-63 212.3 0.3 5.3e-63 212.3 0.3 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAJ26460.1 - 4.8e-17 61.9 0.7 1.8e-16 60.0 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Ndc1_Nup PF09531.10 OAJ26460.1 - 4.4 5.9 7.5 0.54 8.9 3.6 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CclA_1 PF16942.5 OAJ26461.1 - 0.013 15.8 2.0 0.014 15.7 2.0 1.1 1 0 0 1 1 1 0 Putative cyclic bacteriocin Flp_Fap PF04964.14 OAJ26461.1 - 0.013 15.3 1.9 0.019 14.8 0.7 1.8 1 1 1 2 2 2 0 Flp/Fap pilin component SseC PF04888.12 OAJ26461.1 - 1.6 8.2 7.2 1.7 8.2 7.2 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CAP PF00188.26 OAJ26462.1 - 2.9e-23 83.1 4.3 7.6e-23 81.7 4.3 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-Tim10_DDP PF02953.15 OAJ26462.1 - 2.7e-17 62.2 0.4 5.4e-17 61.2 0.4 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger BUD22 PF09073.10 OAJ26463.1 - 1.3e-61 209.3 35.2 2.2e-61 208.5 35.2 1.4 1 1 0 1 1 1 1 BUD22 Ten1_2 PF15490.6 OAJ26464.1 - 5.6e-06 26.1 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit cobW PF02492.19 OAJ26465.1 - 3.3e-32 111.5 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAJ26465.1 - 0.00014 20.9 2.4 0.00093 18.3 2.4 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAJ26465.1 - 0.02 15.5 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAJ26465.1 - 0.024 14.7 0.0 0.21 11.7 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ26465.1 - 0.042 14.2 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OAJ26465.1 - 0.046 13.2 0.0 5.8 6.4 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CbtA PF09490.10 OAJ26465.1 - 0.051 13.3 0.2 0.077 12.7 0.2 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) T2SSE PF00437.20 OAJ26465.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAJ26465.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OAJ26465.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SelP_N PF04592.14 OAJ26465.1 - 0.46 9.9 13.3 0.67 9.3 13.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ufd2P_core PF10408.9 OAJ26466.1 - 1.5e-198 661.4 0.1 1.9e-198 661.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAJ26466.1 - 4.9e-26 90.7 0.4 1.6e-25 89.1 0.4 2.0 1 0 0 1 1 1 1 U-box domain AP1AR PF15745.5 OAJ26466.1 - 0.0049 16.6 0.7 0.054 13.1 0.0 2.5 2 0 0 2 2 2 1 AP-1 complex-associated regulatory protein Sec5 PF15469.6 OAJ26468.1 - 5.2e-55 186.2 2.9 1.1e-54 185.1 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAJ26468.1 - 0.011 15.7 0.4 0.071 13.2 0.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 RINT1_TIP1 PF04437.13 OAJ26468.1 - 0.49 9.2 7.1 0.069 12.0 0.2 2.9 3 2 1 4 4 4 0 RINT-1 / TIP-1 family CENP-H PF05837.12 OAJ26468.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.2 3 1 0 3 3 3 0 Centromere protein H (CENP-H) RRM_1 PF00076.22 OAJ26469.1 - 1.7e-09 37.4 0.0 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_Me_trans PF04252.13 OAJ26470.1 - 2.9e-52 177.2 0.0 3.5e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase UPF0203 PF05254.12 OAJ26472.1 - 2.8e-16 59.5 0.0 2.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) Ndc1_Nup PF09531.10 OAJ26472.1 - 0.047 12.4 1.1 0.052 12.2 1.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UCR_hinge PF02320.16 OAJ26472.1 - 0.1 12.8 0.5 11 6.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SPX PF03105.19 OAJ26472.1 - 2.6 7.9 6.4 3.1 7.6 6.4 1.1 1 0 0 1 1 1 0 SPX domain FAM199X PF15814.5 OAJ26472.1 - 2.7 6.9 9.1 3.4 6.6 9.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X AdoMet_MTase PF07757.13 OAJ26473.1 - 1.4e-30 105.9 0.0 1.6e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 OAJ26473.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pec_lyase_C PF00544.19 OAJ26474.1 - 7e-14 51.9 4.9 1.2e-12 47.9 4.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAJ26474.1 - 1.5e-05 24.9 4.3 0.00013 21.8 3.1 2.3 1 1 1 2 2 2 2 Right handed beta helix region Kelch_5 PF13854.6 OAJ26475.1 - 1.6e-32 110.9 9.8 1.8e-06 27.8 0.3 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OAJ26475.1 - 1.2e-28 98.8 22.6 8.2e-07 28.9 0.2 7.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ26475.1 - 1.5e-28 98.5 20.6 2.6e-08 33.9 0.1 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ26475.1 - 1.1e-24 85.8 11.3 9.2e-07 28.9 0.1 7.1 5 1 2 7 7 7 5 Kelch motif Kelch_1 PF01344.25 OAJ26475.1 - 4.4e-22 77.4 19.1 3.2e-07 29.8 2.6 6.6 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 OAJ26475.1 - 2.3e-16 59.1 16.0 0.0021 18.0 0.2 7.1 6 1 0 6 6 6 5 Kelch motif MAD PF05557.13 OAJ26475.1 - 2.2 6.5 51.3 0.1 10.9 21.5 3.5 2 1 1 3 3 3 0 Mitotic checkpoint protein DAO PF01266.24 OAJ26476.1 - 4e-49 168.1 0.4 4e-49 168.1 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAJ26476.1 - 4e-45 152.7 0.2 8.7e-45 151.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 OAJ26476.1 - 8.9e-07 29.3 1.0 2e-06 28.1 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 OAJ26476.1 - 5.7e-06 25.7 5.0 5.5e-05 22.4 5.0 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAJ26476.1 - 0.00047 19.6 0.9 0.00047 19.6 0.9 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase EF-hand_1 PF00036.32 OAJ26476.1 - 0.0007 19.0 0.6 0.0028 17.1 0.1 2.3 3 0 0 3 3 3 1 EF hand Pyr_redox_2 PF07992.14 OAJ26476.1 - 0.0047 16.2 0.7 0.013 14.8 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.6 OAJ26476.1 - 0.0077 15.7 0.5 0.018 14.6 0.5 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAJ26476.1 - 0.014 15.3 0.1 0.052 13.5 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain GIDA PF01134.22 OAJ26476.1 - 0.02 14.0 0.2 0.18 10.8 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ26476.1 - 0.085 12.1 0.1 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAJ26476.1 - 0.089 12.0 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ26476.1 - 0.1 12.4 0.2 0.27 11.1 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_8 PF13833.6 OAJ26476.1 - 0.44 10.4 3.3 1.1 9.2 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair Vac7 PF12751.7 OAJ26478.1 - 0.0017 17.9 0.2 0.002 17.6 0.2 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 MRC1 PF09444.10 OAJ26478.1 - 0.74 10.3 10.0 1.3 9.6 10.0 1.3 1 0 0 1 1 1 0 MRC1-like domain MMS1_N PF10433.9 OAJ26479.1 - 1.1e-144 482.7 0.0 1.7e-144 482.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAJ26479.1 - 2.4e-79 267.0 0.0 6.5e-79 265.6 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region Proteasome PF00227.26 OAJ26480.1 - 4.9e-24 84.9 0.2 5.5e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-B_box PF00643.24 OAJ26481.1 - 0.61 10.3 3.3 0.85 9.8 3.3 1.2 1 0 0 1 1 1 0 B-box zinc finger 4HBT_2 PF13279.6 OAJ26482.1 - 1.3e-08 35.3 0.0 1.6e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAJ26482.1 - 2.3e-05 24.6 0.0 3.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 OAJ26482.1 - 0.016 14.5 0.2 0.045 13.0 0.2 1.6 2 0 0 2 2 2 0 Acyl-ACP thioesterase DUF778 PF05608.12 OAJ26483.1 - 0.17 12.2 1.8 0.18 12.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Podoplanin PF05808.11 OAJ26483.1 - 0.91 9.6 3.9 1.5 8.9 3.7 1.4 1 1 0 1 1 1 0 Podoplanin ADH_N PF08240.12 OAJ26484.1 - 2.3e-26 91.8 1.7 3.7e-26 91.1 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ26484.1 - 4e-10 39.8 0.0 8.5e-08 32.2 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAJ26484.1 - 0.00045 20.1 0.8 0.0013 18.6 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 OAJ26484.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PCI PF01399.27 OAJ26485.1 - 5.3e-15 55.8 0.0 2.5e-14 53.6 0.0 2.1 2 1 0 2 2 2 1 PCI domain SRC-1 PF08832.10 OAJ26485.1 - 5.8 8.0 5.7 2.3 9.3 0.4 2.8 3 0 0 3 3 3 0 Steroid receptor coactivator EPL1 PF10513.9 OAJ26486.1 - 0.1 13.0 2.9 0.14 12.5 2.9 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like NST1 PF13945.6 OAJ26486.1 - 1.7 8.7 13.7 2.3 8.3 13.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SNARE PF05739.19 OAJ26487.1 - 7e-16 58.0 0.1 1.3e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAJ26487.1 - 8.3e-07 28.9 2.0 0.0025 17.5 0.5 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 OAJ26487.1 - 4.1e-05 22.7 0.7 4.1e-05 22.7 0.7 2.0 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain SlyX PF04102.12 OAJ26487.1 - 0.0071 16.9 0.3 0.079 13.6 0.3 2.7 2 0 0 2 2 2 1 SlyX DUF148 PF02520.17 OAJ26487.1 - 0.016 15.3 4.3 0.045 13.9 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 Use1 PF09753.9 OAJ26487.1 - 0.03 14.1 0.3 0.069 12.9 0.1 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 FlaC_arch PF05377.11 OAJ26487.1 - 0.039 14.4 1.0 0.12 12.8 0.9 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 OAJ26487.1 - 0.14 12.6 2.2 0.25 11.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 OAJ26487.1 - 0.26 11.3 7.0 2.3 8.3 0.3 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 OAJ26487.1 - 0.46 10.8 3.3 3.9 7.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein SKA2 PF16740.5 OAJ26487.1 - 2.7 7.8 4.5 14 5.5 0.3 2.8 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 OAJ26487.1 - 6.1 7.4 6.3 81 3.8 0.3 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Topoisom_I_N PF02919.15 OAJ26488.1 - 5.3e-80 267.9 1.3 5.3e-80 267.9 1.3 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 OAJ26488.1 - 1.1e-68 231.0 2.2 1.4e-68 230.6 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 OAJ26488.1 - 2.1e-17 62.8 0.2 1.7e-14 53.5 0.1 3.0 2 0 0 2 2 2 2 C-terminal topoisomerase domain DUF5423 PF17461.2 OAJ26488.1 - 4.2 6.1 11.3 2.6 6.8 8.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5423) PseudoU_synth_2 PF00849.22 OAJ26488.1 - 7.1 6.7 10.1 0.4 10.8 4.1 2.0 2 0 0 2 2 2 0 RNA pseudouridylate synthase EPSP_synthase PF00275.20 OAJ26489.1 - 4.3e-38 131.1 0.0 5.4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HTH_3 PF01381.22 OAJ26489.1 - 0.0014 18.7 0.0 0.099 12.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix HSP20 PF00011.21 OAJ26490.1 - 2.1e-18 66.4 0.8 8.3e-13 48.4 0.2 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAJ26490.1 - 7.2e-05 22.3 0.0 0.00043 19.8 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PEX11 PF05648.14 OAJ26491.1 - 1.6e-13 50.7 0.0 1.1e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Dscam_C PF12355.8 OAJ26491.1 - 0.0029 18.6 0.2 0.0048 17.9 0.2 1.3 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal Pkinase PF00069.25 OAJ26493.1 - 4.4e-73 245.9 0.0 6.2e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ26493.1 - 1.8e-34 119.2 0.0 3e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ26493.1 - 0.0073 15.3 0.0 0.32 9.9 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ26493.1 - 0.0086 15.4 0.0 0.018 14.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like TFIIA PF03153.13 OAJ26493.1 - 2 8.3 22.1 2.4 8.1 22.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAJ26493.1 - 3.3 7.7 5.2 4.6 7.2 5.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region L51_S25_CI-B8 PF05047.16 OAJ26495.1 - 6.1e-10 38.9 0.2 9.6e-10 38.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Rad51 PF08423.11 OAJ26496.1 - 5.1e-14 52.1 0.1 4e-12 45.9 0.0 3.0 3 0 0 3 3 3 1 Rad51 RecA PF00154.21 OAJ26496.1 - 2.1e-05 24.2 0.1 3.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OAJ26496.1 - 0.00013 21.6 0.2 0.00044 19.9 0.1 1.9 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 OAJ26496.1 - 0.00014 21.3 0.1 0.00031 20.2 0.1 1.5 1 0 0 1 1 1 1 KaiC HSP20 PF00011.21 OAJ26497.1 - 2.1e-18 66.4 0.8 8.3e-13 48.4 0.2 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAJ26497.1 - 7.2e-05 22.3 0.0 0.00043 19.8 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Inhibitor_I9 PF05922.16 OAJ26506.1 - 8.9e-08 32.7 0.0 3.1e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 OAJ26506.1 - 0.054 13.3 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Brix PF04427.18 OAJ26507.1 - 2.6e-36 125.6 0.0 3.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain YL1 PF05764.13 OAJ26507.1 - 0.00054 20.2 21.2 0.0064 16.6 9.8 2.2 2 0 0 2 2 2 2 YL1 nuclear protein CDC45 PF02724.14 OAJ26507.1 - 0.038 12.3 16.8 0.012 13.9 6.5 2.1 2 0 0 2 2 2 0 CDC45-like protein PTPRCAP PF15713.5 OAJ26507.1 - 0.18 12.1 19.4 0.094 13.0 5.8 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 OAJ26507.1 - 0.33 10.3 22.7 0.055 12.9 6.2 2.4 3 0 0 3 3 3 0 SDA1 XAP5 PF04921.14 OAJ26507.1 - 2.1 8.1 17.8 0.36 10.6 1.7 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator Sigma70_ner PF04546.13 OAJ26507.1 - 2.4 8.0 14.5 3.1 7.6 4.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Spt5_N PF11942.8 OAJ26507.1 - 3.5 8.7 28.5 0.27 12.2 2.3 3.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.11 OAJ26507.1 - 3.6 5.6 10.8 0.5 8.4 2.7 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CPSF100_C PF13299.6 OAJ26507.1 - 3.7 7.7 8.7 6.3 6.9 1.2 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CPSase_L_D2 PF02786.17 OAJ26508.1 - 9.1e-73 244.2 0.0 8.4e-72 241.1 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAJ26508.1 - 1.1e-45 154.7 0.1 3.9e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ26508.1 - 3.4e-35 120.4 0.0 7.1e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ26508.1 - 1.3e-13 50.6 2.1 2.6e-13 49.6 2.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAJ26508.1 - 5e-08 32.7 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAJ26508.1 - 1e-05 25.2 0.1 2.6e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 OAJ26508.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAJ26508.1 - 0.001 19.8 1.9 1.7 9.4 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.19 OAJ26508.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SMYLE_N PF18615.1 OAJ26508.1 - 0.23 11.0 1.9 0.32 10.5 1.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAJ26509.1 - 2.5e-42 144.6 0.9 4.3e-42 143.8 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ26509.1 - 2.2e-33 115.3 0.0 4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ26509.1 - 2.8e-27 94.8 0.0 4.9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ26509.1 - 2.6e-16 60.1 0.3 4.2e-16 59.4 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mre11_DNA_bind PF04152.14 OAJ26510.1 - 7.1e-43 146.8 5.4 7.1e-43 146.8 5.4 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAJ26510.1 - 3.2e-12 47.4 0.3 5.9e-12 46.5 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAJ26510.1 - 1.4e-06 28.6 0.2 3.9e-05 23.9 0.2 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF573 PF04504.14 OAJ26510.1 - 0.017 15.7 0.0 0.051 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DHFR_1 PF00186.19 OAJ26511.1 - 1.2e-25 90.1 0.0 2.7e-22 79.2 0.0 2.4 2 0 0 2 2 2 2 Dihydrofolate reductase SUIM_assoc PF16619.5 OAJ26511.1 - 4.8e-07 29.8 0.0 0.095 12.8 0.0 2.5 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 dsDNA_bind PF01984.20 OAJ26511.1 - 0.0063 16.8 3.5 0.25 11.7 0.1 2.2 2 0 0 2 2 2 2 Double-stranded DNA-binding domain SSF PF00474.17 OAJ26512.1 - 1.1e-20 74.0 20.1 1.8e-20 73.2 20.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family S-AdoMet_synt_C PF02773.16 OAJ26513.1 - 2.7e-67 225.0 0.3 7e-67 223.7 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAJ26513.1 - 2.8e-46 156.6 0.0 5.1e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAJ26513.1 - 3.2e-45 152.9 0.2 6.4e-45 151.9 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OAJ26513.1 - 0.025 13.4 0.0 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) GST_N_2 PF13409.6 OAJ26514.1 - 1.4e-10 41.3 0.0 2.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ26514.1 - 2.2e-10 40.8 0.0 4.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAJ26514.1 - 2.6e-09 37.3 0.1 4.5e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ26514.1 - 1.3e-08 34.7 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ26514.1 - 1.4e-06 28.4 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ26514.1 - 4.1e-06 26.9 0.0 8.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAJ26514.1 - 7e-05 23.4 0.0 0.00026 21.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAJ26514.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Dfp1_Him1_M PF08630.10 OAJ26515.1 - 4e-33 114.3 0.0 8.3e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAJ26515.1 - 3.8e-20 71.7 0.7 8.7e-20 70.6 0.7 1.7 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 OAJ26515.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 OAJ26515.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain MBOAT_2 PF13813.6 OAJ26516.1 - 7.1e-14 51.8 0.2 4.6e-06 26.8 0.1 3.1 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Polysacc_deac_1 PF01522.21 OAJ26517.1 - 3.5e-14 52.8 0.0 7.4e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Ribophorin_I PF04597.14 OAJ26518.1 - 2.2e-111 373.2 0.3 2.3e-110 369.8 0.3 1.9 1 1 0 1 1 1 1 Ribophorin I WD40 PF00400.32 OAJ26519.1 - 2.8e-07 31.1 5.9 3.2 8.8 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Sec16 PF12932.7 OAJ26519.1 - 0.026 15.1 0.0 0.092 13.3 0.0 2.0 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region SRA1 PF07304.11 OAJ26519.1 - 0.11 12.2 0.2 0.65 9.8 0.0 2.4 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) FMO-like PF00743.19 OAJ26520.1 - 2.2e-09 36.3 0.0 2.8e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAJ26520.1 - 1.3e-08 34.9 0.0 8.6e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ26520.1 - 5e-08 32.5 0.2 0.024 13.9 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ26520.1 - 1.1e-07 31.5 0.0 0.038 13.2 0.0 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ26520.1 - 4.1e-07 30.1 0.5 0.0033 17.4 0.1 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAJ26520.1 - 3.3e-06 26.5 0.0 0.00034 19.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAJ26520.1 - 0.00014 21.6 0.1 0.0045 16.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OAJ26520.1 - 0.053 12.6 0.2 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAJ26520.1 - 0.082 12.1 0.1 0.33 10.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Rep_fac_C PF08542.11 OAJ26520.1 - 0.22 12.0 0.0 7.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Replication factor C C-terminal domain Pyr_redox_2 PF07992.14 OAJ26521.1 - 1.2e-14 54.2 0.0 4.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ26521.1 - 2.1e-12 47.0 0.6 8.7e-12 44.9 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAJ26521.1 - 8.1e-11 41.0 0.0 1.3e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAJ26521.1 - 4.5e-08 33.2 0.0 9.3e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ26521.1 - 3.8e-07 30.0 2.3 0.0025 17.4 0.1 3.7 3 2 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ26521.1 - 6.6e-07 28.8 0.1 0.003 16.7 0.0 3.1 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAJ26521.1 - 1.7e-06 27.5 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAJ26521.1 - 0.00053 19.2 0.1 0.0021 17.2 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain Mqo PF06039.15 OAJ26521.1 - 0.00065 18.4 0.1 0.27 9.7 0.0 2.6 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 OAJ26521.1 - 0.0012 18.8 0.7 1.7 8.6 0.1 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAJ26521.1 - 0.0025 16.9 0.3 0.54 9.3 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAJ26521.1 - 0.0054 17.3 0.0 9.1 6.9 0.1 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAJ26521.1 - 0.021 14.9 0.0 2.2 8.3 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAJ26521.1 - 0.028 13.5 0.2 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAJ26521.1 - 0.04 13.3 0.2 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAJ26521.1 - 0.068 12.4 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAJ26521.1 - 0.21 10.2 0.3 0.86 8.2 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein TENA_THI-4 PF03070.16 OAJ26522.1 - 3e-12 46.8 0.0 6.4e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Pap_E4 PF02711.14 OAJ26523.1 - 0.096 13.7 2.7 0.12 13.4 2.7 1.3 1 0 0 1 1 1 0 E4 protein WLM PF08325.10 OAJ26523.1 - 0.18 11.9 1.5 0.29 11.2 1.5 1.3 1 0 0 1 1 1 0 WLM domain SARAF PF06682.12 OAJ26523.1 - 0.27 10.8 5.7 0.3 10.7 5.7 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 OAJ26523.1 - 0.45 10.9 3.0 0.52 10.7 3.0 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1180 PF06679.12 OAJ26523.1 - 0.81 10.1 6.9 0.91 9.9 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4719 PF15843.5 OAJ26523.1 - 2.6 8.1 6.3 3.1 7.9 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) zf-C3HC4 PF00097.25 OAJ26524.1 - 1.6e-07 31.1 1.2 1.6e-07 31.1 1.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ26524.1 - 2.2e-06 27.4 5.2 5e-06 26.3 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ26524.1 - 2.8e-06 27.6 3.9 9.4e-06 25.9 1.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ26524.1 - 4.3e-06 26.6 2.8 4.3e-06 26.6 2.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ26524.1 - 8.6e-06 25.5 4.5 6.2e-05 22.8 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ26524.1 - 0.00035 20.5 1.6 0.00035 20.5 1.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAJ26524.1 - 0.002 18.2 4.1 0.002 18.2 4.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ26524.1 - 0.17 11.8 6.6 1.4 8.8 2.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ26524.1 - 0.18 12.1 1.2 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain MAJIN PF15077.6 OAJ26524.1 - 6.1 6.6 7.4 0.29 10.9 0.8 2.1 3 0 0 3 3 3 0 Membrane-anchored junction protein Complex1_LYR PF05347.15 OAJ26525.1 - 7e-05 22.8 1.7 0.0003 20.8 0.9 2.4 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Methyltransf_23 PF13489.6 OAJ26525.1 - 0.00054 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 OAJ26525.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_31 PF13847.6 OAJ26525.1 - 0.22 11.3 0.0 0.67 9.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Spc7 PF08317.11 OAJ26526.1 - 4.8e-15 55.2 8.6 7.8e-15 54.6 8.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 OAJ26526.1 - 8.7e-05 22.5 0.3 0.00018 21.5 0.3 1.5 1 0 0 1 1 1 1 Spc7_C2 KELK PF15796.5 OAJ26526.1 - 0.33 11.4 4.3 1.4 9.4 4.4 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 OAJ26526.1 - 0.37 10.1 5.3 0.65 9.3 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Wbp11 PF09429.10 OAJ26526.1 - 0.4 11.1 5.8 0.22 12.0 2.5 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 Snf7 PF03357.21 OAJ26527.1 - 1.3e-31 109.6 13.9 1.7e-31 109.1 13.9 1.2 1 0 0 1 1 1 1 Snf7 Bac_GDH PF05088.12 OAJ26527.1 - 0.083 10.4 6.9 0.085 10.3 6.9 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase TIP39 PF14980.6 OAJ26527.1 - 0.11 12.4 2.1 0.3 11.0 2.1 1.7 1 0 0 1 1 1 0 TIP39 peptide RRM_1 PF00076.22 OAJ26528.1 - 1.7e-16 59.8 0.0 3.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ26528.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 OAJ26528.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif NOA36 PF06524.12 OAJ26528.1 - 0.28 10.5 11.9 0.49 9.7 11.9 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 OAJ26528.1 - 0.34 9.4 4.0 0.46 9.0 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dicty_REP PF05086.12 OAJ26528.1 - 0.98 7.3 5.8 1.3 6.9 5.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MSP1_C PF07462.11 OAJ26528.1 - 4 6.0 9.1 5.3 5.6 9.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sporozoite_P67 PF05642.11 OAJ26528.1 - 6.1 4.8 9.0 8.7 4.3 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 OAJ26528.1 - 7.6 4.6 19.0 0.065 11.4 8.8 1.9 2 0 0 2 2 2 0 Nop14-like family AMPK1_CBM PF16561.5 OAJ26529.1 - 5e-11 42.7 0.8 9.2e-11 41.8 0.8 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glt_symporter PF03616.14 OAJ26529.1 - 4.4 5.9 5.1 7.1 5.2 0.1 2.9 3 0 0 3 3 3 0 Sodium/glutamate symporter DNA_pol_phi PF04931.13 OAJ26530.1 - 2.4 6.2 5.3 3.1 5.8 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peroxin-13_N PF04088.13 OAJ26531.1 - 4.5e-41 140.5 0.0 6.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 OAJ26531.1 - 3e-12 46.0 0.0 5.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ26531.1 - 7.6e-12 44.7 0.0 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAJ26531.1 - 1.2e-09 37.8 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ATP-synt_C PF00137.21 OAJ26532.1 - 2.1e-27 95.3 33.0 5.3e-15 55.5 11.3 3.1 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 OAJ26532.1 - 0.024 14.2 1.1 0.024 14.2 1.1 3.0 3 1 1 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.22 OAJ26533.1 - 1e-45 155.2 0.0 1.3e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ26533.1 - 6.2e-16 58.7 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ26533.1 - 3.7e-07 29.8 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ26533.1 - 6.5e-05 22.9 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ26533.1 - 0.0015 18.1 0.1 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ26533.1 - 0.013 14.8 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glutaredoxin PF00462.24 OAJ26533.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin MMR_HSR1 PF01926.23 OAJ26533.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OAJ26533.1 - 0.034 14.2 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OAJ26533.1 - 0.059 12.9 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 OAJ26533.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OAJ26533.1 - 0.2 12.1 0.0 0.25 11.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain NUDIX_2 PF13869.6 OAJ26534.1 - 3.3e-79 264.9 0.0 3.7e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Mito_carr PF00153.27 OAJ26535.1 - 3.9e-65 215.8 2.6 1e-21 76.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Meth_synt_2 PF01717.18 OAJ26536.1 - 0.22 10.8 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain PARP PF00644.20 OAJ26537.1 - 2.1e-07 30.7 0.1 3.2e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 OAJ26538.1 - 6.6e-14 52.5 0.3 7.8e-14 52.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OAJ26538.1 - 0.0018 18.1 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 HECW1_helix PF18436.1 OAJ26538.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 PARP PF00644.20 OAJ26539.1 - 6.4e-14 52.0 0.4 1.6e-09 37.7 0.0 2.9 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Fasciclin PF02469.22 OAJ26539.1 - 0.023 14.9 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain DNA_pol3_delta2 PF13177.6 OAJ26539.1 - 0.043 13.6 0.2 0.06 13.1 0.2 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit zf-HC5HC2H PF13771.6 OAJ26539.1 - 0.36 11.1 5.7 6.1 7.2 1.2 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C4pol PF14260.6 OAJ26539.1 - 0.6 10.6 4.6 2.2 8.8 0.5 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta NUP PF06516.11 OAJ26540.1 - 2.2e-121 404.9 0.2 2.6e-121 404.7 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Aldo_ket_red PF00248.21 OAJ26541.1 - 3.9e-46 157.6 0.0 4.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HxlR PF01638.17 OAJ26541.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix Keratin_2_head PF16208.5 OAJ26542.1 - 0.033 14.3 10.4 0.04 14.0 10.4 1.1 1 0 0 1 1 1 0 Keratin type II head CNH PF00780.22 OAJ26544.1 - 6.3e-35 121.1 0.0 1.2e-34 120.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAJ26544.1 - 2.2e-21 76.9 0.2 3.7e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAJ26544.1 - 0.00054 20.0 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 OAJ26544.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Fungal_trans PF04082.18 OAJ26545.1 - 0.058 12.4 1.2 0.13 11.2 0.2 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ26545.1 - 0.064 13.4 3.5 0.11 12.7 3.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.11 OAJ26547.1 - 1.8e-74 250.6 5.5 3e-57 194.1 0.1 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 OAJ26547.1 - 0.0054 15.9 0.1 0.0091 15.2 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter DBI_PRT PF02277.17 OAJ26547.1 - 0.094 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase SRF-TF PF00319.18 OAJ26548.1 - 4.6e-16 58.0 0.1 7.3e-16 57.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Serglycin PF04360.12 OAJ26548.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 3.2 3 0 0 3 3 3 1 Serglycin Spt20 PF12090.8 OAJ26548.1 - 0.028 14.0 1.6 0.064 12.8 1.6 1.6 1 0 0 1 1 1 0 Spt20 family YL1 PF05764.13 OAJ26548.1 - 4.1 7.5 6.4 0.9 9.6 0.1 2.4 3 0 0 3 3 3 0 YL1 nuclear protein SUIM_assoc PF16619.5 OAJ26548.1 - 6.6 6.9 15.8 0.23 11.6 8.2 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MIP PF00230.20 OAJ26554.1 - 6.7e-22 78.3 9.6 1.5e-11 44.5 1.3 2.1 1 1 1 2 2 2 2 Major intrinsic protein Rbx_binding PF18113.1 OAJ26554.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain Sdh_cyt PF01127.22 OAJ26554.1 - 0.16 12.0 1.5 2.6 8.1 0.3 2.6 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Bud13 PF09736.9 OAJ26554.1 - 1 9.7 8.9 1.6 9.1 8.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NPAT_C PF15712.5 OAJ26554.1 - 2.8 6.5 5.9 4.8 5.7 5.9 1.2 1 0 0 1 1 1 0 NPAT C terminus CTP_transf_like PF01467.26 OAJ26555.1 - 1.8e-26 93.1 0.0 2.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Pro_isomerase PF00160.21 OAJ26556.1 - 2.4e-28 99.4 0.0 3.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAJ26556.1 - 1.5e-13 50.4 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pirin PF02678.16 OAJ26557.1 - 1.1e-27 96.2 0.0 2.1e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 OAJ26557.1 - 9.6e-24 83.7 0.0 2.2e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAJ26557.1 - 0.0097 15.6 0.6 0.047 13.4 0.7 2.0 2 0 0 2 2 2 1 Cupin domain Abhydrolase_5 PF12695.7 OAJ26558.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ26558.1 - 0.071 12.4 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAJ26558.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family EspF PF04806.12 OAJ26559.1 - 0.12 12.8 6.7 0.33 11.4 4.6 2.8 2 0 0 2 2 2 0 EspF protein repeat Plus-3 PF03126.18 OAJ26560.1 - 1.5e-14 54.5 0.0 2.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain CLASP_N PF12348.8 OAJ26561.1 - 2.2e-17 63.4 0.0 0.00014 21.6 0.0 5.3 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 OAJ26561.1 - 2.4e-13 49.1 14.4 0.00092 19.3 0.1 9.2 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 OAJ26561.1 - 8.8e-11 42.1 4.8 0.038 14.0 0.0 6.4 7 0 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ26561.1 - 1e-09 38.6 8.5 0.056 13.8 0.0 8.2 7 2 1 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 OAJ26561.1 - 6.9e-05 23.3 4.4 3.3 8.3 0.1 5.9 5 0 0 5 5 5 2 HEAT-like repeat TAN PF11640.8 OAJ26561.1 - 0.00014 22.0 0.4 1.8 8.7 0.0 5.2 5 0 0 5 5 5 1 Telomere-length maintenance and DNA damage repair Vac14_Fab1_bd PF12755.7 OAJ26561.1 - 0.00075 20.0 0.0 43 4.8 0.0 5.5 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 OAJ26561.1 - 0.0049 16.6 0.0 4.2 7.1 0.0 4.4 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 OAJ26561.1 - 0.015 15.6 1.2 2.1 8.7 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Proteasom_PSMB PF10508.9 OAJ26561.1 - 0.015 13.8 0.0 11 4.4 0.0 3.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 OAJ26561.1 - 0.03 14.5 0.1 4.6 7.4 0.0 4.2 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 OAJ26561.1 - 3.9 7.7 9.3 0.78 9.9 0.0 4.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat WD40_4 PF16300.5 OAJ26562.1 - 4.4e-21 74.5 2.3 1.2e-14 54.0 0.0 2.7 2 0 0 2 2 2 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 OAJ26562.1 - 0.014 15.7 0.1 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ26562.1 - 0.16 12.9 6.5 1.9 9.5 0.1 3.8 3 1 1 4 4 4 0 WD domain, G-beta repeat DUF1899 PF08953.11 OAJ26562.1 - 0.19 11.6 0.1 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) MFS_1 PF07690.16 OAJ26563.1 - 6.6e-28 97.6 44.2 1.8e-26 92.9 38.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NTF2 PF02136.20 OAJ26564.1 - 0.015 15.9 0.0 0.36 11.4 0.0 2.7 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 OAJ26564.1 - 0.069 13.1 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 IATP PF04568.12 OAJ26564.1 - 0.72 10.3 2.8 1.2 9.6 1.9 1.8 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Lipase_3 PF01764.25 OAJ26566.1 - 0.0088 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ26566.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IKI3 PF04762.12 OAJ26568.1 - 7.1e-233 775.6 0.0 9.1e-233 775.2 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Se-cys_synth_N PF12390.8 OAJ26568.1 - 0.0003 21.0 1.7 0.00082 19.5 0.3 2.6 2 0 0 2 2 2 1 Selenocysteine synthase N terminal ANAPC4_WD40 PF12894.7 OAJ26568.1 - 0.055 13.8 0.0 6.9 7.1 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CCDC106 PF15794.5 OAJ26568.1 - 0.12 12.1 4.1 0.22 11.2 4.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nup35_RRM PF05172.13 OAJ26569.1 - 3e-06 27.1 0.0 6.8e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ26569.1 - 0.00034 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_M24 PF00557.24 OAJ26570.1 - 1.8e-46 158.5 0.0 2.3e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3663 PF12404.8 OAJ26570.1 - 0.051 13.6 0.3 8.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Peptidase RRM_1 PF00076.22 OAJ26572.1 - 5.1e-08 32.6 0.9 0.012 15.4 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BSP_II PF05432.11 OAJ26572.1 - 2.9 7.5 48.6 1 9.0 34.6 3.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PCI PF01399.27 OAJ26573.1 - 1.7e-10 41.3 0.2 6e-10 39.6 0.2 2.0 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.13 OAJ26573.1 - 0.39 10.4 7.5 0.83 9.3 0.0 3.6 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF882) Methyltr_RsmB-F PF01189.17 OAJ26574.1 - 1e-17 64.5 0.2 5.1e-09 36.1 0.1 3.4 2 1 1 3 3 3 3 16S rRNA methyltransferase RsmB/F HWE_HK PF07536.14 OAJ26574.1 - 0.051 14.3 0.3 0.051 14.3 0.3 2.5 3 0 0 3 3 3 0 HWE histidine kinase DUF4710 PF15828.5 OAJ26574.1 - 0.055 13.6 8.8 0.99 9.6 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) TSGP1 PF07771.11 OAJ26574.1 - 1.6 8.9 4.7 4.5 7.4 4.7 1.7 1 0 0 1 1 1 0 Tick salivary peptide group 1 Sas10_Utp3 PF04000.15 OAJ26575.1 - 8.3e-14 52.0 0.3 2.7e-13 50.3 0.3 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF3245 PF11595.8 OAJ26575.1 - 3.7 8.0 19.7 0.57 10.7 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) CDC45 PF02724.14 OAJ26575.1 - 5.5 5.2 14.9 9.9 4.3 14.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ26575.1 - 7.3 4.7 15.7 13 3.9 15.7 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 OAJ26575.1 - 7.9 5.1 6.7 11 4.6 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_60s PF00428.19 OAJ26575.1 - 8.3 7.1 19.1 8.9 7.0 7.3 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein SRAP PF02586.14 OAJ26576.1 - 1.3e-58 198.2 0.0 1.1e-57 195.1 0.0 2.2 2 1 0 2 2 2 1 SOS response associated peptidase (SRAP) DUF2052 PF09747.9 OAJ26576.1 - 4.1 7.5 11.0 7.4 6.7 8.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Amastin PF07344.11 OAJ26577.1 - 1.2 9.0 9.7 0.26 11.1 5.6 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.20 OAJ26577.1 - 5.8 6.8 9.6 0.32 10.8 3.4 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family LysM PF01476.20 OAJ26578.1 - 1.8e-05 24.7 0.1 6.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 LysM domain Zn_clus PF00172.18 OAJ26579.1 - 0.0002 21.4 11.6 0.0002 21.4 11.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 OAJ26579.1 - 0.00031 20.7 0.0 0.00076 19.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold SNF2_N PF00176.23 OAJ26580.1 - 9.4e-63 212.0 0.3 1.5e-62 211.4 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ26580.1 - 3.2e-18 66.1 0.0 7.8e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 OAJ26580.1 - 1.4e-17 63.9 2.1 1.4e-17 63.9 2.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 OAJ26580.1 - 1.4e-13 50.5 1.5 1.4e-08 34.5 0.4 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OAJ26580.1 - 7.6e-11 42.3 0.1 3.7e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 OAJ26580.1 - 3.6e-07 30.8 0.2 3.6e-07 30.8 0.2 3.1 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 OAJ26580.1 - 0.029 14.4 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 SLIDE Cdh1_DBD_1 PF18196.1 OAJ26580.1 - 0.067 13.5 0.1 0.067 13.5 0.1 4.5 4 0 0 4 4 4 0 Chromodomain helicase DNA-binding domain 1 TFIIIC_delta PF12657.7 OAJ26581.1 - 3.4e-05 23.8 0.2 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OAJ26581.1 - 0.04 13.9 0.8 0.092 12.7 0.8 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex TRAPP PF04051.16 OAJ26582.1 - 7.1e-35 119.9 0.0 8.7e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GCSF PF16647.5 OAJ26582.1 - 0.0028 17.5 0.4 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Granulocyte colony-stimulating factor MetallophosN PF16371.5 OAJ26582.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase DUF1752 PF08550.10 OAJ26583.1 - 3.2e-11 42.9 4.7 7.3e-11 41.7 4.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WD40 PF00400.32 OAJ26585.1 - 1.5e-19 70.0 13.4 3e-07 31.0 0.1 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ26585.1 - 1.3e-08 35.1 0.2 0.11 12.8 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Semialdhyde_dhC PF02774.18 OAJ26589.1 - 2e-42 145.3 0.1 3.5e-42 144.6 0.0 1.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAJ26589.1 - 1.5e-27 96.4 0.0 3.3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAJ26589.1 - 0.0012 18.9 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 OAJ26589.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 OAJ26589.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ribosomal_L28 PF00830.19 OAJ26590.1 - 2.3e-20 72.5 0.2 4.3e-20 71.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Brix PF04427.18 OAJ26591.1 - 1.2e-30 107.0 0.1 1.6e-30 106.7 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF4128 PF13554.6 OAJ26591.1 - 0.0042 17.1 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage related domain of unknown function DUF2517 PF10725.9 OAJ26591.1 - 0.031 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Per1 PF04080.13 OAJ26592.1 - 1.5e-91 306.7 0.2 2.1e-91 306.2 0.2 1.2 1 0 0 1 1 1 1 Per1-like family Arf PF00025.21 OAJ26593.1 - 3e-67 225.4 0.1 3.6e-67 225.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ26593.1 - 1.8e-12 47.1 1.5 6.4e-07 28.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OAJ26593.1 - 1.1e-11 44.9 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ26593.1 - 3.3e-09 36.4 0.0 4.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ26593.1 - 9.4e-08 31.7 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OAJ26593.1 - 1.4e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAJ26593.1 - 5.8e-06 26.4 0.0 8.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ26593.1 - 0.013 15.0 0.0 0.14 11.7 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OAJ26593.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OAJ26593.1 - 0.076 12.5 0.1 0.24 10.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.6 OAJ26593.1 - 0.22 11.2 0.3 0.28 10.8 0.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain BRE1 PF08647.11 OAJ26594.1 - 2.7e-19 69.0 10.6 2.7e-19 69.0 10.6 7.9 5 3 1 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 OAJ26594.1 - 1.3e-06 28.2 13.9 2.3e-06 27.4 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ26594.1 - 1.9e-06 27.6 9.8 3.7e-06 26.7 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ26594.1 - 1.3e-05 25.0 3.3 2.6e-05 24.0 3.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OAJ26594.1 - 1.7e-05 24.7 7.1 3.3e-05 23.8 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ26594.1 - 2e-05 24.4 12.5 4e-05 23.5 12.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ26594.1 - 2.3e-05 24.1 11.6 4e-05 23.4 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ26594.1 - 0.00064 20.0 11.0 0.0011 19.3 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ribbon_3 PF13248.6 OAJ26594.1 - 0.00092 18.5 2.3 0.002 17.5 0.6 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Fez1 PF06818.15 OAJ26594.1 - 0.0015 19.0 14.9 0.0015 19.0 14.9 5.3 4 1 1 5 5 4 3 Fez1 ATG16 PF08614.11 OAJ26594.1 - 0.0062 16.8 7.5 0.0062 16.8 7.5 7.4 5 2 1 7 7 7 3 Autophagy protein 16 (ATG16) zf-rbx1 PF12678.7 OAJ26594.1 - 0.0073 16.6 6.8 0.015 15.6 6.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAJ26594.1 - 0.0078 16.1 8.8 0.014 15.3 8.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PolyA_pol PF01743.20 OAJ26594.1 - 0.016 15.7 1.0 0.016 15.7 1.0 3.8 4 1 0 4 4 4 0 Poly A polymerase head domain Seryl_tRNA_N PF02403.22 OAJ26594.1 - 0.016 15.4 4.7 0.016 15.4 4.7 8.4 4 3 2 8 8 8 0 Seryl-tRNA synthetase N-terminal domain CM_2 PF01817.21 OAJ26594.1 - 0.036 14.4 4.8 0.06 13.7 0.1 3.8 3 0 0 3 3 2 0 Chorismate mutase type II zf-C3HC4_4 PF15227.6 OAJ26594.1 - 0.086 13.0 10.5 0.056 13.6 8.7 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 OAJ26594.1 - 0.14 12.2 4.5 0.35 11.0 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OAJ26594.1 - 0.54 10.3 6.8 1.1 9.3 6.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 OAJ26594.1 - 0.77 9.6 4.6 1.7 8.5 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FlaC_arch PF05377.11 OAJ26594.1 - 2.6 8.5 21.1 1.6 9.2 0.8 6.7 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) zf-C3HC4_5 PF17121.5 OAJ26594.1 - 3.9 7.4 5.3 8.9 6.3 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) T2SSF PF00482.23 OAJ26595.1 - 0.25 11.3 2.7 0.2 11.6 0.5 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1690 PF07956.11 OAJ26596.1 - 6.9e-25 88.1 3.2 6.9e-25 88.1 3.2 2.1 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) GIT1_C PF12205.8 OAJ26596.1 - 0.0082 16.2 0.2 0.0082 16.2 0.2 2.2 2 1 1 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term ATP-synt_D PF01813.17 OAJ26596.1 - 0.011 15.5 1.0 0.014 15.2 0.1 1.6 2 1 0 2 2 2 0 ATP synthase subunit D Apolipoprotein PF01442.18 OAJ26596.1 - 0.026 14.4 16.8 0.026 14.4 15.0 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tcp11 PF05794.13 OAJ26596.1 - 0.062 12.4 8.0 0.13 11.3 8.0 1.5 1 1 0 1 1 1 0 T-complex protein 11 Macoilin PF09726.9 OAJ26596.1 - 0.1 11.1 18.8 0.16 10.5 18.8 1.3 1 0 0 1 1 1 0 Macoilin family Rootletin PF15035.6 OAJ26596.1 - 0.19 11.7 8.1 1.1 9.2 8.1 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 OAJ26596.1 - 0.45 10.8 3.3 0.66 10.3 1.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GREB1 PF15782.5 OAJ26596.1 - 1.2 6.1 8.6 1.1 6.3 8.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LMBR1 PF04791.16 OAJ26596.1 - 1.4 7.7 4.6 1.6 7.6 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF883 PF05957.13 OAJ26596.1 - 4.2 8.0 18.6 1.1 9.9 2.3 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Lant_dehydr_C PF14028.6 OAJ26596.1 - 4.7 6.7 7.0 10 5.6 4.2 2.3 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Tape_meas_lam_C PF09718.10 OAJ26596.1 - 5.8 7.1 9.3 0.96 9.6 1.9 2.8 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Herpes_pp85 PF04637.12 OAJ26596.1 - 8.3 4.7 9.4 12 4.2 9.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SlyX PF04102.12 OAJ26596.1 - 8.4 7.1 7.3 18 6.0 0.3 3.4 3 0 0 3 3 3 0 SlyX Ndc1_Nup PF09531.10 OAJ26596.1 - 8.4 4.9 8.8 8.7 4.9 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XRN_M PF17846.1 OAJ26596.1 - 9.2 5.1 7.6 8.3 5.2 6.8 1.3 1 1 0 1 1 1 0 Xrn1 helical domain TP_methylase PF00590.20 OAJ26597.1 - 3.9e-16 59.6 0.3 1.7e-15 57.5 0.1 2.1 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases FTR1 PF03239.14 OAJ26598.1 - 1.8e-54 185.0 4.9 1.8e-34 119.3 2.9 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.16 OAJ26598.1 - 0.043 12.7 0.7 0.071 12.0 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Cu-oxidase_2 PF07731.14 OAJ26599.1 - 1e-38 132.1 6.9 2.8e-37 127.5 2.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ26599.1 - 1.3e-35 122.8 0.1 2.8e-32 112.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAJ26599.1 - 2.3e-14 53.5 8.6 1.4e-12 47.6 1.3 3.6 4 1 0 4 4 4 2 Multicopper oxidase CLP1_P PF16575.5 OAJ26600.1 - 1.8e-27 96.4 0.0 2.2e-22 79.8 0.0 3.0 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OAJ26600.1 - 2.1e-23 83.0 0.0 3.7e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 OAJ26600.1 - 2.4e-17 62.9 0.0 3.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_28 PF13521.6 OAJ26600.1 - 0.0077 16.5 0.0 0.033 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAJ26600.1 - 0.028 14.5 0.0 0.13 12.4 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ26600.1 - 0.13 12.6 0.7 0.32 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Pro_CA PF00484.19 OAJ26600.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase SurE PF01975.17 OAJ26601.1 - 2.8e-41 141.4 0.0 2.2e-40 138.5 0.0 2.2 1 1 0 1 1 1 1 Survival protein SurE LisH PF08513.11 OAJ26603.1 - 0.00087 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 LisH Vps51 PF08700.11 OAJ26604.1 - 5.6e-22 77.6 0.1 1.3e-21 76.4 0.0 1.6 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 OAJ26604.1 - 0.001 19.2 0.4 0.0014 18.8 0.4 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 OAJ26604.1 - 0.0023 16.7 0.5 0.0031 16.3 0.5 1.1 1 0 0 1 1 1 1 Dor1-like family SKA2 PF16740.5 OAJ26604.1 - 0.004 16.9 0.1 0.0069 16.2 0.1 1.4 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF1744 PF08490.12 OAJ26604.1 - 0.073 11.6 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Vps52 PF04129.12 OAJ26604.1 - 0.16 10.7 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family NPC1_N PF16414.5 OAJ26605.1 - 3.7e-63 213.3 5.8 3.7e-63 213.3 5.8 3.2 2 1 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAJ26605.1 - 1.3e-61 208.8 10.1 5.2e-38 130.7 0.3 3.1 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 OAJ26605.1 - 1.4e-45 154.8 6.5 3.7e-23 82.1 0.2 2.9 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OAJ26605.1 - 0.0027 15.4 4.1 0.0039 14.9 4.1 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MFS_Mycoplasma PF07672.13 OAJ26605.1 - 0.04 13.2 0.3 0.14 11.4 0.3 1.8 1 0 0 1 1 1 0 Mycoplasma MFS transporter Prothymosin PF03247.14 OAJ26606.1 - 2.1 8.8 21.6 0.056 13.9 10.8 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family F-box-like PF12937.7 OAJ26607.1 - 0.087 12.7 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 F-box-like SNARE PF05739.19 OAJ26608.1 - 6e-11 42.2 0.3 6e-11 42.2 0.3 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 OAJ26608.1 - 1.3e-10 41.5 4.1 2.7e-10 40.5 1.6 2.3 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 OAJ26608.1 - 0.00073 19.3 9.9 0.0021 17.8 1.5 2.3 2 0 0 2 2 2 2 Syntaxin Caskin1-CID PF16600.5 OAJ26608.1 - 0.02 15.5 1.2 0.06 13.9 1.2 1.8 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain DUF5345 PF17280.2 OAJ26608.1 - 0.26 11.3 1.9 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Peptidase_S8 PF00082.22 OAJ26609.1 - 4e-31 108.4 8.7 7.7e-31 107.4 8.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAJ26609.1 - 7.5e-12 45.8 0.2 1.7e-11 44.6 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 AA_permease_2 PF13520.6 OAJ26611.1 - 3.3e-60 204.1 38.7 4e-60 203.8 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ26611.1 - 8.1e-27 93.9 33.9 1.1e-26 93.5 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3246 PF11596.8 OAJ26611.1 - 6.4 6.1 7.7 3.9 6.8 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Pkinase PF00069.25 OAJ26612.1 - 4.1e-54 183.7 0.0 1e-33 116.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ26612.1 - 8.2e-23 81.0 0.1 2.5e-15 56.5 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ26612.1 - 0.0021 18.0 2.5 0.028 14.4 0.4 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ26612.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 OAJ26612.1 - 0.058 14.1 0.0 0.19 12.5 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Kinase-like PF14531.6 OAJ26612.1 - 0.085 12.2 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DnaJ PF00226.31 OAJ26613.1 - 1e-16 60.8 0.1 2.7e-16 59.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 OAJ26613.1 - 3.4e-13 50.4 4.8 3.4e-13 50.4 4.8 3.2 3 0 0 3 3 3 1 Ribosome-associated complex head domain AAA_23 PF13476.6 OAJ26613.1 - 0.34 11.4 9.1 0.65 10.5 9.1 1.5 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 OAJ26613.1 - 2.8 6.6 6.4 4.2 6.0 6.4 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OAJ26613.1 - 3.8 5.5 6.2 5 5.1 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribonuc_2-5A PF06479.12 OAJ26615.1 - 3.2e-41 140.5 0.0 5.2e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 OAJ26615.1 - 1.8e-38 132.5 0.0 4.1e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ26615.1 - 8e-20 71.2 0.0 5.2e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAJ26615.1 - 0.0002 20.8 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ26615.1 - 0.00023 20.1 0.0 0.00064 18.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 OAJ26615.1 - 0.00038 20.2 0.1 0.0072 16.2 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.6 OAJ26615.1 - 0.0042 16.7 0.1 0.32 10.5 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain SUIM_assoc PF16619.5 OAJ26615.1 - 0.9 9.7 6.4 0.13 12.4 1.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Nucleoporin_N PF08801.11 OAJ26616.1 - 4.2e-59 200.4 0.0 6.8e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAJ26616.1 - 3.8e-33 115.1 5.1 6.1e-33 114.4 5.1 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal CitMHS PF03600.16 OAJ26617.1 - 6.5e-12 45.3 13.5 6.5e-12 45.3 13.5 2.1 2 1 0 2 2 2 1 Citrate transporter ArsB PF02040.15 OAJ26617.1 - 5.2e-11 42.5 17.1 8.5e-07 28.6 5.5 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein SPA PF08616.10 OAJ26618.1 - 1.1e-47 160.7 0.0 3e-35 120.6 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 OAJ26618.1 - 2.5e-24 86.2 0.0 2.5e-23 83.0 0.0 2.2 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OAJ26618.1 - 3.5e-09 35.9 0.0 0.0005 18.9 0.0 4.4 3 2 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 OAJ26618.1 - 0.15 11.6 0.0 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) EF_TS PF00889.19 OAJ26619.1 - 1.9e-12 47.3 0.0 2.1e-11 43.9 0.0 2.7 3 1 0 3 3 3 1 Elongation factor TS FUSC_2 PF13515.6 OAJ26621.1 - 3.3e-16 59.6 17.1 3.3e-16 59.6 17.1 3.0 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAJ26621.1 - 4.4e-12 45.6 0.1 1.3e-11 44.1 0.1 1.8 1 1 0 1 1 1 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 OAJ26621.1 - 1.1e-08 34.6 0.1 1.1e-08 34.6 0.1 4.1 4 1 0 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 OAJ26621.1 - 5.7e-08 31.8 19.3 5.7e-08 31.8 19.3 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein family ArAE_1 PF06081.11 OAJ26621.1 - 6.7e-06 26.3 8.6 2.2e-05 24.7 8.6 1.9 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 ArAE_2 PF10334.9 OAJ26621.1 - 4.8e-05 23.3 0.9 0.0002 21.3 1.3 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 MbeB_N PF04837.12 OAJ26621.1 - 0.27 11.6 3.1 0.38 11.1 0.2 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Peptidase_M28 PF04389.17 OAJ26622.1 - 3.8e-37 127.9 0.0 5.8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAJ26622.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SMC_N PF02463.19 OAJ26623.1 - 1.2e-20 73.9 0.0 2.5e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ26623.1 - 2.2e-18 67.5 0.0 2.2e-18 67.5 0.0 5.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 OAJ26623.1 - 0.00013 21.7 0.1 0.0014 18.3 0.0 2.7 3 1 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ26623.1 - 0.0016 18.3 3.5 0.0028 17.5 0.3 3.0 2 2 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAJ26623.1 - 0.002 17.9 4.1 0.002 17.9 4.1 3.6 2 2 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 OAJ26623.1 - 0.096 13.2 0.0 0.096 13.2 0.0 5.1 3 2 0 3 3 3 0 ABC transporter Surfac_D-trimer PF09006.11 OAJ26623.1 - 7.7 6.5 7.0 8.9 6.3 0.7 3.6 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation AAA_13 PF13166.6 OAJ26623.1 - 9.3 4.7 66.0 2.8 6.5 0.0 4.8 3 2 1 4 4 4 0 AAA domain WD40 PF00400.32 OAJ26624.1 - 0.00049 20.8 11.8 0.22 12.4 0.3 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ26624.1 - 0.00058 20.3 1.0 7 7.3 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain SAPS PF04499.15 OAJ26624.1 - 0.14 10.9 2.2 0.23 10.2 2.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 OAJ26624.1 - 0.42 8.8 24.9 0.77 7.9 24.9 1.4 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ26624.1 - 0.85 8.9 34.0 19 4.5 32.2 2.4 2 0 0 2 2 2 0 BUD22 TFIIA PF03153.13 OAJ26624.1 - 4.5 7.2 22.6 19 5.1 19.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit COG2 PF06148.11 OAJ26625.1 - 0.02 14.9 0.5 0.02 14.9 0.5 5.3 2 1 3 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 PAM2 PF07145.15 OAJ26625.1 - 0.35 10.7 2.0 8.7 6.3 0.2 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Fructosamin_kin PF03881.14 OAJ26633.1 - 9.4e-59 199.0 0.0 1.5e-58 198.3 0.0 1.3 1 1 1 2 2 2 1 Fructosamine kinase APH PF01636.23 OAJ26633.1 - 7.9e-06 26.0 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 OAJ26634.1 - 3.6e-74 250.3 17.1 3.9e-70 237.0 8.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ26634.1 - 3.9e-15 55.6 23.3 3.9e-15 55.6 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sin3a_C PF16879.5 OAJ26635.1 - 3.9e-76 256.5 0.1 2.3e-75 254.0 0.0 2.4 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 OAJ26635.1 - 4.1e-42 142.1 8.2 7.9e-18 64.3 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OAJ26635.1 - 4.2e-41 139.0 0.3 4.2e-41 139.0 0.3 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Metallophos PF00149.28 OAJ26636.1 - 1.5e-39 136.6 0.0 2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ26636.1 - 4e-21 75.2 0.4 8.9e-21 74.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DAO PF01266.24 OAJ26637.1 - 1.2e-21 77.7 7.2 5e-20 72.4 7.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ26637.1 - 0.0051 16.1 0.0 0.12 11.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ26637.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CysA_C_terminal PF17850.1 OAJ26637.1 - 0.1 13.2 0.5 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 CysA C-terminal regulatory domain CENP-T_C PF15511.6 OAJ26637.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RFX_DNA_binding PF02257.15 OAJ26638.1 - 5.1e-22 78.3 0.2 9e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain HPHLAWLY PF14925.6 OAJ26639.1 - 0.02 13.6 9.5 0.049 12.3 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function Glyco_hydro_47 PF01532.20 OAJ26640.1 - 4.6e-143 477.4 0.0 5.8e-143 477.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Bystin PF05291.11 OAJ26641.1 - 8.6e-111 369.9 0.0 1.1e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Bystin Cwf_Cwc_15 PF04889.12 OAJ26641.1 - 0.15 11.8 9.3 0.24 11.1 9.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 OAJ26641.1 - 0.22 11.1 8.7 0.31 10.6 8.7 1.2 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 OAJ26641.1 - 9 4.7 7.2 13 4.2 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Shugoshin_C PF07557.11 OAJ26642.1 - 1.9e-15 56.3 23.3 1.6e-10 40.5 5.3 4.0 3 0 0 3 3 3 3 Shugoshin C terminus RNA_pol_3_Rpc31 PF11705.8 OAJ26642.1 - 3.7 7.7 40.4 1.1 9.5 12.5 3.5 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 BRCT_2 PF16589.5 OAJ26643.1 - 0.03 14.7 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Vac_ImportDeg PF09783.9 OAJ26644.1 - 2.2e-50 170.7 0.0 1.8e-46 157.9 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein Methyltransf_11 PF08241.12 OAJ26645.1 - 4.2e-11 43.4 0.0 1.4e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ26645.1 - 6.3e-10 39.1 0.0 9.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ26645.1 - 6.6e-09 36.4 0.0 1.3e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ26645.1 - 2.4e-07 31.4 0.1 8.3e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ26645.1 - 0.0012 18.7 0.0 0.0039 17.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain ANAPC4_WD40 PF12894.7 OAJ26646.1 - 3.9e-06 27.1 0.0 0.0067 16.7 0.0 5.0 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ26646.1 - 0.00043 21.0 12.5 0.11 13.4 0.0 5.6 6 1 0 6 6 6 2 WD domain, G-beta repeat FAM176 PF14851.6 OAJ26646.1 - 0.15 11.7 3.2 1.8 8.2 0.8 2.7 2 0 0 2 2 2 0 FAM176 family Ge1_WD40 PF16529.5 OAJ26646.1 - 0.23 10.4 0.0 1.5 7.7 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AA_kinase PF00696.28 OAJ26647.1 - 7.2e-32 110.9 0.2 9e-32 110.6 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family Dynamin_N PF00350.23 OAJ26648.1 - 1.8e-41 142.0 0.0 3.3e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAJ26648.1 - 4e-05 23.7 0.0 0.00016 21.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 OAJ26648.1 - 0.0009 18.5 0.0 0.0029 16.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region AAA_15 PF13175.6 OAJ26648.1 - 0.052 13.3 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAJ26648.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_S58 PF03576.14 OAJ26648.1 - 0.075 12.5 2.6 0.25 10.8 2.2 1.9 2 0 0 2 2 2 0 Peptidase family S58 Vps52 PF04129.12 OAJ26649.1 - 6.5e-40 137.3 0.0 5.4e-37 127.7 0.0 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 OAJ26649.1 - 5.3e-05 21.8 0.0 7.6e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Cwf_Cwc_15 PF04889.12 OAJ26649.1 - 0.056 13.2 13.7 4 7.1 0.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 OAJ26649.1 - 0.11 12.9 7.2 0.21 12.0 7.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OAJ26649.1 - 0.22 9.8 4.0 0.31 9.3 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ26649.1 - 0.54 9.5 11.7 0.79 9.0 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OAJ26649.1 - 1.2 8.8 4.0 2.3 7.9 4.0 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 OAJ26649.1 - 2.9 7.7 6.5 1 9.2 3.2 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 OAJ26649.1 - 3.1 5.8 12.8 4.8 5.2 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ26649.1 - 6.8 4.8 10.3 1.4 7.0 6.6 1.6 2 0 0 2 2 2 0 Nop14-like family EHN PF06441.12 OAJ26651.1 - 4.4e-20 72.1 0.2 8.9e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ26651.1 - 1.2e-11 44.8 0.1 2.6e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Gaa1 PF04114.14 OAJ26651.1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component LRR_8 PF13855.6 OAJ26652.1 - 1.6e-13 50.2 15.4 5.1e-09 35.8 6.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ26652.1 - 3.8e-13 49.4 8.9 1.9e-05 24.9 2.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ26652.1 - 0.46 10.7 13.5 9.4 6.6 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OAJ26652.1 - 0.61 10.9 12.7 24 6.0 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat MFS_1 PF07690.16 OAJ26653.1 - 1.4e-22 80.1 29.5 8.8e-18 64.3 10.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAJ26653.1 - 3.6e-09 36.0 0.0 0.013 14.4 2.7 3.3 2 1 1 3 3 3 3 MFS_1 like family ATG22 PF11700.8 OAJ26653.1 - 0.079 11.6 14.6 0.011 14.4 1.8 2.5 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DJ-1_PfpI PF01965.24 OAJ26654.1 - 5.7e-11 42.5 0.0 1.5e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAJ26654.1 - 6.3e-06 26.0 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 OAJ26654.1 - 0.067 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DEAD PF00270.29 OAJ26655.1 - 7.8e-30 103.9 0.0 5.8e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26655.1 - 1.2e-21 77.1 0.0 4.1e-21 75.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ26655.1 - 0.0099 15.9 0.0 0.064 13.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 OAJ26655.1 - 4.1 5.5 18.4 8.3 4.5 18.4 1.4 1 0 0 1 1 1 0 Nop14-like family Cmc1 PF08583.10 OAJ26656.1 - 3.7e-17 62.1 1.3 5.4e-17 61.6 1.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Tfb4 PF03850.14 OAJ26657.1 - 4.9e-38 131.2 14.2 9.2e-20 71.3 8.1 3.0 1 1 1 2 2 2 2 Transcription factor Tfb4 CAF1A PF12253.8 OAJ26659.1 - 6e-23 80.8 6.7 6e-23 80.8 6.7 4.3 2 2 1 3 3 3 1 Chromatin assembly factor 1 subunit A Mitofilin PF09731.9 OAJ26659.1 - 0.0089 14.9 36.1 0.016 14.1 36.1 1.4 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Borrelia_P83 PF05262.11 OAJ26659.1 - 0.043 12.3 35.2 0.075 11.5 35.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein HGTP_anticodon2 PF12745.7 OAJ26659.1 - 0.41 10.1 25.1 0.99 8.9 25.1 1.6 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CAF-1_p150 PF11600.8 OAJ26659.1 - 0.94 9.2 59.1 0.034 13.8 52.0 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BAF1_ABF1 PF04684.13 OAJ26659.1 - 7.8 5.4 33.2 15 4.5 0.2 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Mpp10 PF04006.12 OAJ26660.1 - 0.059 11.8 3.1 0.069 11.6 3.1 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 OAJ26660.1 - 0.089 12.4 4.4 0.2 11.2 4.4 1.6 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 OAJ26660.1 - 0.19 11.2 5.4 0.25 10.7 5.4 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 OAJ26660.1 - 0.2 11.5 1.3 0.3 11.0 1.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 OAJ26660.1 - 0.31 10.4 5.9 0.5 9.7 5.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 OAJ26660.1 - 0.5 10.8 15.1 1.3 9.5 15.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 OAJ26660.1 - 0.94 7.7 4.0 1.2 7.3 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ26660.1 - 1 7.5 7.1 1.3 7.1 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ26660.1 - 2.7 6.0 8.9 3.5 5.6 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi COPI_C PF06957.11 OAJ26660.1 - 2.7 6.7 4.0 4 6.1 4.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.12 OAJ26660.1 - 9 5.5 11.7 14 4.9 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein NPR2 PF06218.11 OAJ26661.1 - 1.6e-98 330.3 0.2 5.3e-43 147.4 0.3 5.1 3 2 1 4 4 4 4 Nitrogen permease regulator 2 NPR3 PF03666.13 OAJ26661.1 - 0.00092 18.1 1.1 0.09 11.6 0.3 2.2 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 OAJ26661.1 - 1 7.6 2.2 2.2 6.6 2.2 1.4 1 0 0 1 1 1 0 Menin GAS2 PF02187.17 OAJ26662.1 - 8.3e-12 45.0 0.0 2.8e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain HAMP PF00672.25 OAJ26662.1 - 1.2 9.6 3.7 3.9 7.9 0.1 3.7 3 0 0 3 3 3 0 HAMP domain Gp-FAR-1 PF05823.12 OAJ26662.1 - 2.4 8.5 6.1 8.2 6.8 0.0 4.4 4 2 0 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-MYND PF01753.18 OAJ26663.1 - 4.7e-10 39.4 13.0 4.7e-10 39.4 13.0 2.8 2 1 0 2 2 2 1 MYND finger SET PF00856.28 OAJ26663.1 - 1.4e-06 28.8 0.1 5.5e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 SET domain zinc_ribbon_4 PF13717.6 OAJ26663.1 - 0.45 10.5 4.8 1.8 8.6 1.9 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 OAJ26663.1 - 2.1 8.1 5.0 14 5.4 1.4 3.1 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ATP_bind_1 PF03029.17 OAJ26664.1 - 2.4e-83 279.6 0.0 3.2e-81 272.7 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAJ26664.1 - 4.2e-05 23.4 0.0 0.0069 16.2 0.0 2.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 OAJ26664.1 - 0.0003 20.9 0.0 0.00045 20.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 OAJ26664.1 - 0.0013 19.0 0.5 0.032 14.5 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 OAJ26664.1 - 0.0013 18.5 0.0 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ26664.1 - 0.0036 17.5 1.0 0.0094 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAJ26664.1 - 0.0047 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 OAJ26664.1 - 0.0049 16.8 0.0 0.34 10.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 OAJ26664.1 - 0.0064 15.9 0.0 0.028 13.8 0.0 1.9 1 1 0 1 1 1 1 KaiC AAA_18 PF13238.6 OAJ26664.1 - 0.007 16.9 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ26664.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 OAJ26664.1 - 0.026 14.0 0.1 0.65 9.5 0.0 2.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.17 OAJ26664.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 OAJ26664.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAJ26664.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ26664.1 - 0.039 14.3 0.2 0.22 11.9 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain ADSL_C PF10397.9 OAJ26664.1 - 0.047 14.2 0.2 0.1 13.2 0.2 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus RNA_helicase PF00910.22 OAJ26664.1 - 0.069 13.5 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 OAJ26664.1 - 0.088 13.1 0.1 4 7.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 OAJ26664.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 OAJ26664.1 - 0.13 12.7 0.0 1.6 9.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 OAJ26664.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain KTI12 PF08433.10 OAJ26664.1 - 0.17 11.3 0.0 0.71 9.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 OAJ26664.1 - 0.18 11.7 0.0 1.9 8.4 0.0 2.3 1 1 0 1 1 1 0 NTPase BTB PF00651.31 OAJ26666.1 - 0.00065 19.9 0.0 0.00095 19.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain AlaDh_PNT_N PF05222.15 OAJ26667.1 - 3.5e-28 98.6 0.0 5.4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain ThiC-associated PF13667.6 OAJ26667.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 ThiC-associated domain Cyclin_N PF00134.23 OAJ26668.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.8 4 0 0 4 4 4 0 Cyclin, N-terminal domain DUF2722 PF10846.8 OAJ26668.1 - 5.1 5.9 17.7 0.29 10.0 11.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AAA_12 PF13087.6 OAJ26674.1 - 4.2e-45 153.8 0.0 6.3e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ26674.1 - 9.3e-39 133.8 0.0 2.9e-38 132.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ26674.1 - 4.6e-14 53.0 0.0 2.3e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ26674.1 - 3.4e-10 40.0 0.5 5.2e-08 32.8 0.5 2.7 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OAJ26674.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OAJ26674.1 - 0.00032 20.5 0.1 4.8 6.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAJ26674.1 - 0.054 13.9 1.2 0.17 12.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain ResIII PF04851.15 OAJ26674.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OAJ26674.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.14 OAJ26674.1 - 0.13 12.3 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) OTU PF02338.19 OAJ26676.1 - 5.9e-13 49.4 0.0 9.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAJ26676.1 - 0.0072 15.8 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain AFG1_ATPase PF03969.16 OAJ26677.1 - 0.21 10.5 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase Rad21_Rec8_N PF04825.13 OAJ26678.1 - 0.052 13.7 0.2 0.22 11.7 0.0 1.8 1 1 1 2 2 2 0 N terminus of Rad21 / Rec8 like protein PTS_EIIA_2 PF00359.22 OAJ26678.1 - 0.08 12.9 0.1 0.092 12.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 COX6C PF02937.15 OAJ26678.1 - 0.14 12.3 0.1 0.75 10.0 0.0 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIc Med9 PF07544.13 OAJ26679.1 - 0.00064 19.8 1.2 0.16 12.1 0.2 2.4 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Uds1 PF15456.6 OAJ26679.1 - 0.028 14.6 0.9 0.041 14.1 0.9 1.1 1 0 0 1 1 1 0 Up-regulated During Septation cwf21 PF08312.12 OAJ26679.1 - 0.035 14.3 1.1 0.05 13.8 0.1 1.8 2 0 0 2 2 2 0 cwf21 domain DUF5320 PF17253.2 OAJ26679.1 - 0.08 14.0 0.3 6.8 7.8 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) T3SS_needle_E PF08988.10 OAJ26679.1 - 0.084 13.0 1.2 0.084 13.0 1.2 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF4140 PF13600.6 OAJ26679.1 - 4.8 7.7 6.0 37 4.8 0.1 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Choline_transpo PF04515.12 OAJ26680.1 - 2.9e-52 177.9 7.3 8.6e-52 176.4 4.5 2.6 2 1 0 2 2 2 1 Plasma-membrane choline transporter PNISR PF15996.5 OAJ26680.1 - 3.5 7.9 9.6 9.9 6.4 9.6 1.7 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LIP PF03583.14 OAJ26681.1 - 7.7e-46 156.7 0.1 1.1e-45 156.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 OAJ26681.1 - 0.0019 17.5 0.1 0.073 12.3 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAJ26681.1 - 0.0041 16.6 0.6 0.064 12.7 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family GPI-anchored PF10342.9 OAJ26682.1 - 3.6e-05 24.5 2.6 4.5e-05 24.1 2.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cauli_VI PF01693.16 OAJ26683.1 - 7.7e-21 74.1 6.2 3.7e-14 52.7 3.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin LPD5 PF18799.1 OAJ26683.1 - 0.00083 19.8 0.0 0.86 10.0 0.0 2.3 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 5 Sulfatase PF00884.23 OAJ26683.1 - 0.07 12.5 1.0 0.093 12.1 1.0 1.3 1 0 0 1 1 1 0 Sulfatase Cauli_VI PF01693.16 OAJ26684.1 - 1.8e-16 60.2 0.4 3e-16 59.5 0.4 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin BSD PF03909.17 OAJ26686.1 - 7e-16 58.0 3.2 2e-13 50.1 0.1 3.1 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 OAJ26686.1 - 3.3e-07 30.5 0.0 6.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Hamartin PF04388.12 OAJ26686.1 - 0.61 8.7 4.1 0.98 8.0 4.1 1.4 1 0 0 1 1 1 0 Hamartin protein DUF2722 PF10846.8 OAJ26687.1 - 1.7e-06 27.2 4.7 1.8e-06 27.2 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 OAJ26687.1 - 0.021 14.4 23.7 0.038 13.6 23.7 1.3 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 OAJ26687.1 - 0.048 13.8 1.7 0.071 13.3 1.7 1.2 1 0 0 1 1 1 0 DDHD domain ANAPC_CDC26 PF10471.9 OAJ26687.1 - 0.24 12.2 20.5 0.27 12.1 18.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 OAJ26687.1 - 0.4 11.7 9.6 1.4 9.9 9.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 OAJ26687.1 - 0.46 9.2 4.4 0.59 8.8 4.4 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 OAJ26687.1 - 0.68 9.2 5.9 0.89 8.8 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF853 PF05872.12 OAJ26687.1 - 1 7.8 6.3 1.6 7.3 6.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Androgen_recep PF02166.16 OAJ26687.1 - 1.1 8.1 22.5 0.16 10.8 18.6 1.5 2 0 0 2 2 2 0 Androgen receptor DUF3408 PF11888.8 OAJ26687.1 - 1.5 9.0 7.7 1.4 9.1 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) Med15 PF09606.10 OAJ26687.1 - 1.7 7.2 22.0 0.53 8.9 19.5 1.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DivIC PF04977.15 OAJ26687.1 - 4.2 7.2 13.0 8.5 6.2 13.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 OAJ26688.1 - 0.0044 16.4 4.7 0.0093 15.4 4.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) BIRC6 PF12356.8 OAJ26688.1 - 0.069 12.6 1.1 0.22 11.0 1.1 1.9 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 NOA36 PF06524.12 OAJ26688.1 - 5.2 6.3 6.6 9.6 5.4 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein Serinc PF03348.15 OAJ26688.1 - 7.4 5.4 6.1 3 6.7 3.7 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 OAJ26688.1 - 9.8 6.0 32.3 2.3 8.1 27.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Asp PF00026.23 OAJ26689.1 - 4.6e-44 151.1 0.0 2.1e-43 148.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ26689.1 - 2.6e-05 24.5 3.9 0.0032 17.7 2.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ26689.1 - 0.0003 21.4 0.5 0.047 14.3 0.2 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ26689.1 - 0.0089 16.6 0.2 0.091 13.3 0.1 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF3712 PF12505.8 OAJ26689.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) BB_PF PF18063.1 OAJ26690.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Beta barrel Pore-forming domain Serglycin PF04360.12 OAJ26690.1 - 1.6 8.6 9.8 4.3 7.3 5.6 2.6 2 0 0 2 2 2 0 Serglycin EBP50_C PF09007.11 OAJ26691.1 - 0.033 15.2 0.7 0.048 14.7 0.7 1.3 1 0 0 1 1 1 0 EBP50, C-terminal FA_desaturase PF00487.24 OAJ26691.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase stn_TNFRSF12A PF12191.8 OAJ26691.1 - 0.13 12.4 0.5 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2933 PF11666.8 OAJ26691.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) CFEM PF05730.11 OAJ26691.1 - 0.32 11.1 5.7 0.52 10.4 5.0 1.8 1 1 0 1 1 1 0 CFEM domain Vps35 PF03635.17 OAJ26692.1 - 0 1023.1 0.0 0 1022.5 0.0 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.22 OAJ26692.1 - 1.5e-20 72.8 0.0 2.8e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ26692.1 - 0.0083 15.7 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VHS PF00790.19 OAJ26693.1 - 1.5e-19 70.2 0.2 2.6e-19 69.4 0.2 1.3 1 0 0 1 1 1 1 VHS domain Serglycin PF04360.12 OAJ26693.1 - 4.9 7.1 9.7 0.39 10.7 3.9 2.1 2 0 0 2 2 2 0 Serglycin RINGv PF12906.7 OAJ26695.1 - 7.2e-06 26.0 8.1 2e-05 24.6 2.9 2.4 2 0 0 2 2 2 1 RING-variant domain Zn_ribbon_17 PF17120.5 OAJ26695.1 - 0.091 12.4 1.5 0.25 11.0 1.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 OAJ26695.1 - 0.7 10.3 9.2 0.099 13.0 4.4 1.9 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 OAJ26695.1 - 1.4 9.2 4.7 0.51 10.6 1.6 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain UCH PF00443.29 OAJ26696.1 - 3.5e-47 161.0 0.0 4.3e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ26696.1 - 6.6e-11 42.4 4.6 2.9e-09 37.0 4.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAJ26696.1 - 3.7e-09 36.2 0.0 7.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ26696.1 - 0.023 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ26696.1 - 0.17 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain AP3D1 PF06375.11 OAJ26696.1 - 0.36 11.0 4.0 0.71 10.1 4.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Adaptin_N PF01602.20 OAJ26697.1 - 1.2e-136 456.4 7.4 1.5e-136 456.0 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ26697.1 - 7.9e-63 211.3 3.8 1.2e-59 200.9 0.5 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ26697.1 - 6.9e-19 68.0 2.4 2.6e-06 27.7 0.0 6.2 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 OAJ26697.1 - 1.3e-12 46.8 4.0 0.0012 18.9 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 OAJ26697.1 - 1.5e-07 31.7 1.0 0.33 11.5 0.0 6.7 8 0 0 8 8 8 1 HEAT-like repeat Cnd3 PF12719.7 OAJ26697.1 - 1.2e-05 24.7 0.5 0.0039 16.4 0.0 3.0 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OAJ26697.1 - 0.00016 21.8 2.0 0.76 10.0 0.0 4.5 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAJ26697.1 - 0.0013 18.3 0.2 1.8 8.1 0.0 3.6 3 1 1 4 4 4 2 CLASP N terminal Sec7_N PF12783.7 OAJ26697.1 - 0.067 13.1 1.3 0.21 11.5 0.4 2.2 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Aminoglyc_resit PF10706.9 OAJ26697.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase zf-C2H2 PF00096.26 OAJ26698.1 - 1.4e-05 25.2 12.4 0.07 13.6 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ26698.1 - 3.5e-05 24.0 2.2 3.5e-05 24.0 2.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ26698.1 - 0.00045 20.8 10.8 0.065 14.1 7.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ26698.1 - 0.047 14.0 7.3 0.089 13.1 2.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAJ26698.1 - 0.082 13.4 0.9 0.17 12.3 0.9 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 OAJ26698.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain PAF-AH_p_II PF03403.13 OAJ26700.1 - 1.2e-37 129.3 0.0 8.4e-20 70.6 0.3 3.0 2 2 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAJ26700.1 - 0.031 13.5 1.1 0.78 9.0 0.1 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAJ26700.1 - 0.075 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme 4HBT_3 PF13622.6 OAJ26701.1 - 4.9e-32 112.1 0.2 7.6e-32 111.5 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ26701.1 - 5.8e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase M64_N PF16217.5 OAJ26701.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase M64 N-terminus zf-C2H2_10 PF16588.5 OAJ26702.1 - 0.6 9.9 2.9 0.98 9.2 2.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger HSP70 PF00012.20 OAJ26703.1 - 1e-262 872.7 11.3 1.2e-262 872.5 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ26703.1 - 1.7e-15 56.7 2.1 4.4e-13 48.8 0.7 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OAJ26703.1 - 0.0087 16.5 8.3 1.1 9.7 0.4 3.9 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OAJ26703.1 - 0.0091 15.3 3.8 0.98 8.6 0.9 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Seryl_tRNA_N PF02403.22 OAJ26703.1 - 0.038 14.2 8.8 0.09 13.0 7.9 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Transcrip_reg PF01709.20 OAJ26703.1 - 0.061 12.7 7.4 0.027 13.9 3.7 2.0 2 0 0 2 2 2 0 Transcriptional regulator RVT_2 PF07727.14 OAJ26705.1 - 3.8e-69 233.0 0.0 5.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ26705.1 - 8e-14 51.8 0.0 4.7e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ26705.1 - 7.4e-07 28.9 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Trypan_PARP PF05887.11 OAJ26707.1 - 0.018 15.0 2.6 0.041 13.9 2.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cupin_1 PF00190.22 OAJ26708.1 - 7.5e-40 136.0 0.0 6.1e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAJ26708.1 - 3.8e-26 90.6 0.5 9.2e-14 50.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAJ26708.1 - 4.5e-10 39.6 0.4 3e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAJ26708.1 - 5.7e-07 29.1 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_7 PF12973.7 OAJ26708.1 - 0.00066 19.6 0.2 0.19 11.7 0.0 2.7 2 1 0 2 2 2 1 ChrR Cupin-like domain MannoseP_isomer PF01050.18 OAJ26708.1 - 0.001 18.9 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.12 OAJ26708.1 - 0.014 15.0 0.0 5.8 6.5 0.0 2.5 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 OAJ26708.1 - 0.04 13.6 0.1 0.25 11.1 0.1 2.3 1 1 1 2 2 2 0 Cupin ARD PF03079.14 OAJ26708.1 - 0.052 13.7 0.0 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family GPI PF06560.11 OAJ26708.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) PemK_toxin PF02452.17 OAJ26708.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Sugar_tr PF00083.24 OAJ26709.1 - 3e-119 398.9 18.1 3.1e-118 395.5 18.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ26709.1 - 1.4e-19 70.2 38.9 3.2e-14 52.6 18.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TrkA_TMD PF18613.1 OAJ26709.1 - 0.27 10.7 4.0 9.2 5.8 0.2 2.8 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain DUF441 PF04284.13 OAJ26709.1 - 0.45 10.5 9.3 0.78 9.7 7.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF441) DnaJ PF00226.31 OAJ26715.1 - 2.2e-16 59.7 0.1 4.5e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3245 PF11595.8 OAJ26715.1 - 0.092 13.2 0.3 0.092 13.2 0.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3245) Rav1p_C PF12234.8 OAJ26716.1 - 1.1e-97 328.0 0.0 1.7e-97 327.4 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Oxidored_FMN PF00724.20 OAJ26717.1 - 2.5e-49 168.4 0.0 3.5e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_N PF08240.12 OAJ26718.1 - 1.4e-19 70.0 2.6 2.7e-19 69.1 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ26718.1 - 6.3e-15 55.3 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ26718.1 - 0.00012 21.5 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ26718.1 - 0.00028 21.0 0.0 0.0042 17.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAJ26718.1 - 0.0039 16.5 0.2 0.0088 15.4 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAJ26718.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAJ26718.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 OAJ26718.1 - 0.026 13.9 0.6 0.046 13.1 0.6 1.3 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.22 OAJ26718.1 - 0.04 14.7 0.0 0.086 13.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold XdhC_C PF13478.6 OAJ26718.1 - 0.08 13.4 0.0 0.74 10.3 0.0 2.2 2 1 0 2 2 2 0 XdhC Rossmann domain adh_short PF00106.25 OAJ26719.1 - 5.3e-30 104.3 0.0 7.6e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ26719.1 - 2.5e-26 92.7 0.0 4e-22 78.9 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ26719.1 - 3.1e-05 24.0 2.5 0.018 14.9 0.4 3.0 2 1 0 2 2 2 2 KR domain TFIIB PF00382.19 OAJ26720.1 - 6.6e-39 131.8 2.8 7.2e-22 77.2 0.9 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAJ26720.1 - 3e-12 45.8 1.6 5.3e-12 45.1 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 OAJ26720.1 - 0.011 15.8 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain RB_B PF01857.20 OAJ26720.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 OAJ26720.1 - 0.14 11.9 0.7 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Cyclin, N-terminal domain HARE-HTH PF05066.13 OAJ26720.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain ATG7_N PF16420.5 OAJ26721.1 - 8.4e-81 271.9 0.0 1.2e-80 271.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAJ26721.1 - 4.9e-47 160.3 0.0 8.3e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAJ26721.1 - 0.094 12.8 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MoCF_biosynth PF00994.24 OAJ26722.1 - 1.8e-50 170.3 0.8 8.1e-26 90.4 0.0 2.8 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAJ26722.1 - 6.1e-30 104.1 2.0 1.2e-29 103.1 2.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 OAJ26722.1 - 3.6e-15 55.9 0.1 1e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Pro_CA PF00484.19 OAJ26723.1 - 2.2e-17 63.8 0.1 3.1e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase SNARE PF05739.19 OAJ26724.1 - 5.2e-10 39.2 0.1 1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAJ26724.1 - 0.0001 22.0 10.1 0.0001 22.0 10.1 1.9 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.21 OAJ26724.1 - 0.061 13.1 5.0 0.21 11.4 1.1 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 OAJ26724.1 - 0.076 13.4 9.9 0.16 12.3 0.8 2.5 3 0 0 3 3 3 0 Syntaxin-like protein DUF2797 PF10977.8 OAJ26724.1 - 0.34 10.8 2.3 0.33 10.8 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) DUF1043 PF06295.12 OAJ26724.1 - 0.38 10.8 4.3 11 6.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Diphthamide_syn PF01866.17 OAJ26725.1 - 1.3e-72 244.9 0.0 1.6e-36 126.3 0.0 3.4 2 1 0 2 2 2 2 Putative diphthamide synthesis protein RabGAP-TBC PF00566.18 OAJ26726.1 - 2.1e-26 92.9 0.0 9.6e-26 90.8 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rotamase PF00639.21 OAJ26727.1 - 1e-16 61.7 0.0 2e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OAJ26727.1 - 1.7e-16 60.8 0.0 2.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OAJ26727.1 - 3.4e-07 30.2 3.0 8.5e-07 29.0 1.3 2.1 2 0 0 2 2 2 1 WW domain Yae1_N PF09811.9 OAJ26728.1 - 3.2e-10 39.5 0.4 3.2e-10 39.5 0.4 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal zf-UBR PF02207.20 OAJ26729.1 - 5.7e-15 55.2 14.8 5.7e-15 55.2 14.8 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAJ26729.1 - 5.5e-09 35.7 0.1 2.2e-08 33.8 0.1 2.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 OAJ26729.1 - 0.00096 18.7 0.1 0.0027 17.2 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL ANAPC4_WD40 PF12894.7 OAJ26730.1 - 4.2e-06 27.0 0.0 0.98 9.8 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF100_C PF13299.6 OAJ26730.1 - 0.0008 19.6 2.0 0.0017 18.6 2.0 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal WD40 PF00400.32 OAJ26730.1 - 0.0018 19.1 0.6 11 7.0 0.0 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAJ26730.1 - 0.14 10.9 0.0 3.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like CDC45 PF02724.14 OAJ26730.1 - 0.33 9.2 8.7 0.47 8.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ26730.1 - 1 8.7 16.0 1.5 8.2 16.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAJ26730.1 - 3.8 6.7 14.9 6.1 6.1 14.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ26730.1 - 4.3 5.4 14.8 5.7 5.0 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pex2_Pex12 PF04757.14 OAJ26731.1 - 8.3e-33 113.9 0.0 1.2e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OAJ26731.1 - 0.039 13.8 0.6 0.066 13.1 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RhoGEF PF00621.20 OAJ26732.1 - 1.1e-37 130.1 0.0 1.7e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 OAJ26732.1 - 3.8e-07 29.8 0.2 0.028 14.2 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ26732.1 - 7.7e-06 26.2 0.1 0.00028 21.2 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) PH_17 PF18012.1 OAJ26732.1 - 0.004 16.9 0.1 0.0091 15.7 0.1 1.6 1 0 0 1 1 1 1 PH domain PRIMA1 PF16101.5 OAJ26732.1 - 3.3 7.8 6.7 16 5.5 6.7 2.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GTP_EFTU PF00009.27 OAJ26733.1 - 1.5e-18 67.0 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Lipase_GDSL_2 PF13472.6 OAJ26734.1 - 0.055 13.9 0.2 0.21 12.0 0.0 2.1 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Peroxidase_2 PF01328.17 OAJ26735.1 - 2.1e-24 87.1 0.0 2.5e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Ank_2 PF12796.7 OAJ26737.1 - 0.00066 20.2 0.0 0.00094 19.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ26737.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ26737.1 - 0.0094 16.4 0.1 0.026 15.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 OAJ26737.1 - 0.0098 16.5 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAJ26737.1 - 0.022 15.2 0.1 0.049 14.1 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat DUF2076 PF09849.9 OAJ26737.1 - 2.9 7.9 9.7 3.7 7.5 9.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3439 PF11921.8 OAJ26739.1 - 0.0037 17.2 1.7 0.0068 16.4 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 OAJ26739.1 - 0.11 10.4 0.3 0.14 10.2 0.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA_33 PF13671.6 OAJ26741.1 - 1.9e-15 57.3 4.3 2e-13 50.7 2.1 2.6 2 1 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 OAJ26741.1 - 5.6e-08 33.0 0.1 8.4e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.10 OAJ26741.1 - 1.7e-07 30.9 1.4 4.8e-06 26.2 0.1 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 OAJ26741.1 - 4.4e-07 29.4 0.0 0.0037 16.6 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin CPT PF07931.12 OAJ26741.1 - 0.0009 19.1 0.1 0.13 12.1 0.0 2.2 1 1 1 2 2 2 2 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 OAJ26741.1 - 0.0038 16.4 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 OAJ26741.1 - 0.0092 16.3 0.1 0.031 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ26741.1 - 0.016 15.8 2.1 0.48 11.0 2.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OAJ26741.1 - 0.047 14.1 0.7 5.3 7.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 OAJ26741.1 - 0.057 13.3 0.3 0.28 11.1 0.0 1.9 1 1 0 2 2 2 0 Adenylylsulphate kinase SKI PF01202.22 OAJ26741.1 - 0.11 12.6 0.5 0.51 10.5 0.1 2.0 2 0 0 2 2 2 0 Shikimate kinase Ploopntkinase1 PF18748.1 OAJ26741.1 - 0.21 11.1 0.0 6 6.3 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 PP-binding PF00550.25 OAJ26742.1 - 4.1e-16 59.1 0.2 6.8e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OAJ26742.1 - 6.6e-07 29.5 0.1 1e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier PRD PF00874.20 OAJ26742.1 - 0.22 11.8 0.3 0.36 11.2 0.3 1.3 1 0 0 1 1 1 0 PRD domain Ribosomal_L17 PF01196.19 OAJ26743.1 - 5.2e-27 94.6 0.1 1.5e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Ribosomal_L11_N PF03946.14 OAJ26744.1 - 7.5e-24 83.4 1.0 1.2e-23 82.7 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAJ26744.1 - 1.8e-21 76.4 0.3 2.8e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Clat_adaptor_s PF01217.20 OAJ26745.1 - 1.8e-19 70.1 0.0 2.9e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Dendrin PF15498.6 OAJ26745.1 - 0.1 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin NB-ARC PF00931.22 OAJ26746.1 - 3.2e-05 23.3 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 OAJ26746.1 - 0.0015 18.7 0.1 0.0094 16.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 OAJ26746.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 OAJ26746.1 - 0.0096 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAJ26746.1 - 0.023 15.2 0.0 0.056 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAJ26746.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAJ26746.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ26746.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ26746.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.10 OAJ26746.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.29 OAJ26746.1 - 0.19 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) COesterase PF00135.28 OAJ26747.1 - 1e-68 232.5 0.1 2.1e-60 205.1 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ26747.1 - 0.0028 17.5 0.2 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold KH_8 PF17903.1 OAJ26748.1 - 2.7e-31 107.5 0.0 5.4e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAJ26748.1 - 7.9e-05 22.4 0.2 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 KH domain DUF4604 PF15377.6 OAJ26749.1 - 1.8 8.9 39.1 2.1 8.8 33.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF908 PF06012.12 OAJ26749.1 - 4.8 6.5 6.0 5.1 6.4 6.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Nup84_Nup100 PF04121.13 OAJ26750.1 - 4e-120 402.1 0.0 9.6e-120 400.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 FH2 PF02181.23 OAJ26750.1 - 0.13 11.4 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain ThiF PF00899.21 OAJ26751.1 - 1.2e-17 64.1 0.0 2.6e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 ThiF family Sid-5 PF17204.3 OAJ26751.1 - 0.2 11.9 0.0 0.47 10.7 0.0 1.5 1 0 0 1 1 1 0 Sid-5 family CENP-T_C PF15511.6 OAJ26752.1 - 7.6e-08 32.5 0.1 9.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ26752.1 - 0.00021 21.4 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ26752.1 - 0.00047 20.5 0.0 0.00062 20.1 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAJ26752.1 - 0.00062 20.1 0.1 0.0007 20.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ26752.1 - 0.00091 19.5 0.1 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ26752.1 - 0.05 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HA2 PF04408.23 OAJ26753.1 - 3.4e-21 75.5 0.0 1.7e-20 73.3 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ26753.1 - 4.4e-15 55.8 0.0 1.4e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ26753.1 - 2.1e-13 50.6 0.0 4.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ26753.1 - 1.3e-08 34.8 0.1 2.5e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ26753.1 - 1.1e-06 28.9 0.1 2.7e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ26753.1 - 0.0015 18.9 0.1 0.0032 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ26753.1 - 0.0019 18.0 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAJ26753.1 - 0.0064 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 OAJ26753.1 - 0.015 14.9 0.1 0.037 13.7 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 OAJ26753.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 OAJ26753.1 - 0.036 14.1 0.2 0.3 11.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ26753.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ26753.1 - 0.046 14.1 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 OAJ26753.1 - 0.046 13.8 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 OAJ26753.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAJ26753.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAJ26753.1 - 0.12 11.9 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 OAJ26753.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OAJ26753.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain Metallophos PF00149.28 OAJ26755.1 - 2e-14 54.6 0.4 2.9e-14 54.1 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Far-17a_AIG1 PF04750.14 OAJ26756.1 - 1.3e-35 122.5 6.2 1.6e-35 122.2 6.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Inositol_P PF00459.25 OAJ26757.1 - 2.6e-51 174.7 0.1 4.5e-50 170.7 0.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family ERCC4 PF02732.15 OAJ26758.1 - 3.8e-21 75.9 0.0 6.3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain VGLL4 PF15245.6 OAJ26758.1 - 0.0005 20.2 0.5 0.0005 20.2 0.5 2.0 2 0 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 UIM PF02809.20 OAJ26758.1 - 0.027 14.4 2.6 0.2 11.7 2.6 2.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF515 PF04415.12 OAJ26759.1 - 3.3 6.0 6.8 5.3 5.3 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Exo5 PF09810.9 OAJ26760.1 - 1.5e-56 192.4 0.1 6.1e-50 170.8 0.1 2.6 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease MUG113 PF13455.6 OAJ26761.1 - 1e-11 45.3 0.2 3.2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 OAJ26761.1 - 4.2e-11 43.3 0.0 2.8e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 T5orf172 domain Aminotran_5 PF00266.19 OAJ26762.1 - 7.3e-32 110.7 0.1 1.9e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ26762.1 - 8.2e-07 27.9 0.0 2.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_9 PF08221.11 OAJ26762.1 - 0.078 13.1 0.1 4.3 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain PNK3P PF08645.11 OAJ26763.1 - 1.2e-36 125.9 0.2 2e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAJ26763.1 - 3.2e-20 72.8 0.0 2.4e-17 63.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ26763.1 - 0.043 13.3 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 OAJ26763.1 - 0.089 12.1 0.0 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 OAJ26763.1 - 0.17 12.3 0.1 14 6.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain Methyltransf_23 PF13489.6 OAJ26768.1 - 9.9e-18 64.5 2.4 1.6e-17 63.8 2.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ26768.1 - 3.9e-16 59.5 0.0 4.9e-15 56.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ26768.1 - 3.3e-14 53.3 4.4 8e-13 48.9 0.1 3.1 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ26768.1 - 3.6e-14 52.8 0.1 4.3e-12 46.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ26768.1 - 3.1e-13 50.3 1.6 2.9e-12 47.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ26768.1 - 3.1e-06 26.7 0.1 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAJ26768.1 - 0.0007 19.2 1.4 0.022 14.3 0.1 2.8 1 1 2 3 3 3 1 Methyltransferase small domain NodS PF05401.11 OAJ26768.1 - 0.001 18.8 0.0 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OAJ26768.1 - 0.002 17.2 0.0 0.0053 15.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase AlaDh_PNT_C PF01262.21 OAJ26768.1 - 0.0035 16.7 0.4 0.0055 16.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DREV PF05219.12 OAJ26768.1 - 0.0055 15.8 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase TehB PF03848.14 OAJ26768.1 - 0.007 15.8 0.0 0.91 8.9 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TehB Dsh_C PF12316.8 OAJ26768.1 - 0.01 16.3 3.0 0.028 14.8 1.0 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal PCMT PF01135.19 OAJ26768.1 - 0.012 15.3 0.0 0.19 11.5 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 OAJ26768.1 - 0.038 12.9 0.0 0.71 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) TPMT PF05724.11 OAJ26768.1 - 0.074 12.7 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Zip PF02535.22 OAJ26768.1 - 0.98 8.6 12.9 1.3 8.1 12.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter V-SNARE_C PF12352.8 OAJ26769.1 - 1.1e-17 64.0 7.6 2.4e-17 63.0 7.1 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 OAJ26769.1 - 5.4e-15 55.5 3.7 5.4e-15 55.5 3.7 3.0 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus PNK3P PF08645.11 OAJ26769.1 - 0.0063 16.2 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Prominin PF05478.11 OAJ26769.1 - 0.011 13.7 0.1 0.011 13.7 0.1 1.7 2 0 0 2 2 2 0 Prominin Fusion_gly PF00523.18 OAJ26769.1 - 0.07 11.4 0.2 0.12 10.5 0.2 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF5089 PF17002.5 OAJ26769.1 - 0.09 12.6 4.0 0.4 10.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) YnfE PF17452.2 OAJ26769.1 - 0.11 12.8 0.3 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized YnfE-like Fib_alpha PF08702.10 OAJ26769.1 - 0.12 12.6 6.5 0.89 9.7 2.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Orf78 PF06024.12 OAJ26769.1 - 0.53 10.6 2.0 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) YqjK PF13997.6 OAJ26769.1 - 0.64 10.3 3.5 0.63 10.3 0.5 2.4 2 0 0 2 2 2 0 YqjK-like protein TACC_C PF05010.14 OAJ26769.1 - 0.69 9.7 8.7 1.7 8.4 1.8 2.6 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sigma_reg_N PF13800.6 OAJ26769.1 - 1.3 9.3 4.0 2.3 8.6 4.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf-CpG_bind_C PF12269.8 OAJ26769.1 - 2.4 7.9 4.8 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF4407 PF14362.6 OAJ26769.1 - 3.4 6.9 17.9 35 3.6 17.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3391 PF11871.8 OAJ26769.1 - 4.6 7.8 9.6 15 6.2 2.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Malate_DH PF12434.8 OAJ26769.1 - 6.3 6.9 7.2 1.5 8.9 0.4 3.0 3 0 0 3 3 3 0 Malate dehydrogenase enzyme Spc7 PF08317.11 OAJ26769.1 - 6.6 5.5 11.4 6.4 5.5 3.9 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Gryzun PF07919.12 OAJ26770.1 - 7.7e-11 41.5 0.0 8.2e-05 21.6 0.1 2.3 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 OAJ26770.1 - 0.13 11.8 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 CoA_transf_3 PF02515.17 OAJ26771.1 - 1.3e-63 215.4 0.0 2e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III Carn_acyltransf PF00755.20 OAJ26774.1 - 1.9e-197 657.6 0.0 2.5e-197 657.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rho_GDI PF02115.17 OAJ26775.1 - 8e-54 182.4 0.0 9.7e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Cpn60_TCP1 PF00118.24 OAJ26776.1 - 5.8e-150 500.1 2.7 6.6e-150 500.0 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 OAJ26776.1 - 0.045 13.3 0.1 0.26 10.9 0.1 2.3 3 0 0 3 3 3 0 Propionate catabolism activator Nitro_FeMo-Co PF02579.17 OAJ26776.1 - 0.097 13.0 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor LRR_9 PF14580.6 OAJ26777.1 - 2.8e-60 202.8 0.0 3.8e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OAJ26777.1 - 3.9e-13 49.4 12.5 3.7e-07 30.4 0.7 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ26777.1 - 1.1e-11 44.3 9.8 7.9e-07 28.7 1.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat tRNA_bind_3 PF17176.4 OAJ26777.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 tRNA-binding domain LRR_6 PF13516.6 OAJ26777.1 - 0.026 14.6 0.0 36 4.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Glucan_synthase PF02364.15 OAJ26779.1 - 0 1303.9 0.0 0 1303.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAJ26779.1 - 3.1e-40 137.5 0.0 8.2e-40 136.1 0.0 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Mucin15 PF15672.5 OAJ26779.1 - 0.26 10.7 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 RhoGAP PF00620.27 OAJ26780.1 - 3.5e-36 124.3 0.0 7.6e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF664 PF04978.12 OAJ26780.1 - 3 8.3 6.5 5.2 7.5 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF664) STT3 PF02516.14 OAJ26781.1 - 6.5e-147 490.4 32.1 3.6e-142 474.7 29.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PseudoU_synth_2 PF00849.22 OAJ26782.1 - 1.9e-26 93.1 0.1 2.9e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Y_phosphatase2 PF03162.13 OAJ26783.1 - 3.2e-50 169.9 0.0 3.6e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAJ26783.1 - 0.00055 20.0 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ26783.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HTH_CodY PF08222.11 OAJ26783.1 - 0.16 11.6 0.0 0.66 9.6 0.0 2.0 2 1 0 2 2 2 0 CodY helix-turn-helix domain MIF4G PF02854.19 OAJ26784.1 - 1.1e-54 185.3 1.1 2e-54 184.4 1.1 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 OAJ26784.1 - 3.8e-13 49.4 0.0 1.2e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 FANCI_S2 PF14676.6 OAJ26784.1 - 0.14 12.5 0.2 49 4.2 0.0 3.6 3 0 0 3 3 3 0 FANCI solenoid 2 PPTA PF01239.22 OAJ26786.1 - 1.1e-41 139.4 17.5 1.2e-08 34.4 1.5 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DASH_Ask1 PF08655.10 OAJ26786.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Ask1 Alg6_Alg8 PF03155.15 OAJ26788.1 - 4.1e-116 388.8 5.4 9.5e-86 288.7 0.8 2.4 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 OAJ26788.1 - 0.9 8.9 4.8 7.3 5.9 0.3 2.2 1 1 1 2 2 2 0 ALG3 protein PRKG1_interact PF15898.5 OAJ26789.1 - 0.0029 18.5 9.5 0.0029 18.5 9.5 9.5 3 1 6 10 10 10 1 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 OAJ26789.1 - 0.0058 16.7 11.1 0.0058 16.7 11.1 11.5 4 2 5 10 10 10 1 Centrosome localisation domain of PPC89 SOGA PF11365.8 OAJ26789.1 - 0.017 16.2 5.0 0.017 16.2 5.0 9.1 2 1 9 12 12 12 0 Protein SOGA DASH_Dad1 PF08649.10 OAJ26789.1 - 0.28 11.4 1.2 3.3 8.0 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad1 DEAD PF00270.29 OAJ26790.1 - 3.2e-41 141.0 0.0 5.9e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26790.1 - 5.8e-25 87.8 0.0 2e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAJ26790.1 - 2.1e-17 63.1 1.5 2.1e-17 63.1 1.5 3.1 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.15 OAJ26790.1 - 0.00012 22.1 0.0 0.00041 20.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NECFESHC PF16621.5 OAJ26790.1 - 0.0041 17.1 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 GHMP_kinases_C PF08544.13 OAJ26791.1 - 4.8e-12 46.1 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Ldh_1_N PF00056.23 OAJ26791.1 - 0.0048 17.0 0.1 0.0086 16.2 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GalKase_gal_bdg PF10509.9 OAJ26792.1 - 5.3e-21 73.9 0.0 9.9e-21 73.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAJ26792.1 - 1.1e-13 51.2 1.4 1.1e-13 51.2 1.4 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ26792.1 - 2.4e-11 43.8 0.0 5.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Aconitase PF00330.20 OAJ26793.1 - 1.3e-148 495.8 0.0 1.8e-148 495.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ26793.1 - 1.2e-31 109.8 0.0 2.8e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.9 OAJ26793.1 - 0.0054 16.9 0.1 0.022 14.9 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 WIYLD PF10440.9 OAJ26793.1 - 0.12 12.2 0.3 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Ribosomal_L37e PF01907.19 OAJ26794.1 - 3.2e-26 91.3 13.6 5.7e-26 90.4 13.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 OAJ26794.1 - 0.013 15.5 0.4 0.014 15.4 0.4 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.19 OAJ26794.1 - 0.075 13.0 0.8 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L7Ae PF01248.26 OAJ26795.1 - 2.5e-22 78.4 0.0 2.9e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EnY2 PF10163.9 OAJ26796.1 - 7.5e-12 45.5 0.0 1.9e-11 44.2 0.0 1.6 1 1 1 2 2 2 1 Transcription factor e(y)2 DUF2722 PF10846.8 OAJ26796.1 - 0.023 13.6 1.0 0.018 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Prp18 PF02840.15 OAJ26796.1 - 0.028 14.5 0.7 0.085 12.9 0.9 1.7 1 1 1 2 2 2 0 Prp18 domain RmuC PF02646.16 OAJ26796.1 - 0.049 12.8 3.6 0.056 12.6 3.6 1.1 1 0 0 1 1 1 0 RmuC family Ten1 PF12658.7 OAJ26796.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Spt20 PF12090.8 OAJ26796.1 - 0.22 11.1 6.6 0.23 11.0 6.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF2967 PF11179.8 OAJ26796.1 - 2.3 6.2 5.1 2 6.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DASH_Duo1 PF08651.10 OAJ26797.1 - 4.7e-17 61.5 0.0 7.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 TraT PF05818.12 OAJ26797.1 - 0.18 11.5 4.1 0.32 10.7 4.1 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein rve PF00665.26 OAJ26798.1 - 1.7e-22 79.8 0.1 4.1e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 OAJ26798.1 - 8.5e-07 29.2 0.1 2.7e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 OAJ26798.1 - 3e-06 26.9 0.1 5.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ26798.1 - 2.3e-05 24.1 0.0 8.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ26798.1 - 0.0079 16.0 0.5 0.031 14.0 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain zf-C2H2_10 PF16588.5 OAJ26798.1 - 0.22 11.3 1.9 0.47 10.2 1.9 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger AfsA PF03756.13 OAJ26799.1 - 0.053 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain Cyt-b5 PF00173.28 OAJ26800.1 - 1.2e-12 47.8 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 OAJ26801.1 - 1.4e-05 25.7 4.7 0.012 16.4 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Aldedh PF00171.22 OAJ26802.1 - 3.2e-126 421.6 0.1 4.3e-126 421.1 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 OAJ26803.1 - 4.5e-55 182.4 21.0 2.5e-08 34.4 0.6 11.7 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 OAJ26803.1 - 1.3e-41 141.9 0.0 4.4e-41 140.1 0.0 1.9 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OAJ26803.1 - 7.6e-13 48.6 0.0 0.054 13.8 0.0 8.0 7 2 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ26803.1 - 1.6e-07 30.4 0.1 0.73 8.4 0.1 5.4 5 1 0 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ26803.1 - 3.6e-05 22.7 0.0 0.027 13.2 0.0 4.0 4 1 0 5 5 5 1 Nup133 N terminal like Ge1_WD40 PF16529.5 OAJ26803.1 - 0.0044 16.0 0.0 2 7.3 0.0 4.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ZirS_C PF16583.5 OAJ26803.1 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain PD40 PF07676.12 OAJ26803.1 - 0.068 13.1 0.0 19 5.4 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Chorion_2 PF03964.15 OAJ26803.1 - 8 7.4 13.7 3.9 8.4 5.3 3.1 2 0 0 2 2 2 0 Chorion family 2 HSP70 PF00012.20 OAJ26804.1 - 3.9e-230 765.1 7.4 4.7e-230 764.8 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ26804.1 - 1.4e-18 66.8 0.8 9.7e-18 64.1 0.7 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAJ26804.1 - 0.00082 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 OAJ26804.1 - 0.0036 16.3 0.3 0.043 12.8 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 OAJ26804.1 - 0.011 15.1 0.4 0.024 13.9 0.4 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase ATP-synt_DE PF00401.20 OAJ26804.1 - 0.19 12.0 3.0 4.6 7.6 2.7 2.9 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Adaptin_N PF01602.20 OAJ26805.1 - 5.6e-100 335.4 0.0 4.4e-99 332.4 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ26805.1 - 3e-08 33.9 0.2 3.1e-06 27.3 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OAJ26805.1 - 0.00085 19.5 0.1 0.48 10.6 0.0 3.2 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OAJ26805.1 - 0.019 15.2 3.2 21 5.7 0.0 5.2 4 1 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 OAJ26805.1 - 0.025 15.0 12.9 0.11 12.9 0.1 4.8 5 0 0 5 5 5 0 HEAT repeats Cnd3 PF12719.7 OAJ26805.1 - 0.058 12.6 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OAJ26805.1 - 0.13 12.3 1.3 34 4.7 0.1 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Metallophos PF00149.28 OAJ26806.1 - 8.8e-35 121.1 0.2 1.1e-34 120.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S2 PF00318.20 OAJ26807.1 - 4.8e-52 176.3 0.0 6.6e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 PH PF00169.29 OAJ26815.1 - 2.4e-09 37.7 0.1 4.2e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAJ26815.1 - 0.014 15.8 0.2 0.052 14.0 0.2 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain LSM PF01423.22 OAJ26816.1 - 3.6e-16 58.6 0.1 4.8e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M3 PF01432.20 OAJ26816.1 - 0.1 11.8 0.2 0.12 11.7 0.2 1.0 1 0 0 1 1 1 0 Peptidase family M3 DPBB_1 PF03330.18 OAJ26818.1 - 0.00019 21.7 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Rgp1 PF08737.10 OAJ26819.1 - 3.3e-83 280.2 0.0 7.9e-83 278.9 0.0 1.7 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 OAJ26819.1 - 1.2e-06 28.7 0.1 0.1 12.7 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 OAJ26819.1 - 0.048 13.2 0.0 9.5 5.7 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein Methyltransf_8 PF05148.15 OAJ26820.1 - 6.6e-52 176.5 0.0 8.2e-26 91.2 0.0 3.1 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_25 PF13649.6 OAJ26820.1 - 0.0032 18.1 0.1 2.1 9.1 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.14 OAJ26820.1 - 0.005 16.4 0.1 0.8 9.2 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 OAJ26820.1 - 0.023 14.5 0.0 0.68 9.7 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ26820.1 - 0.029 15.0 0.0 0.75 10.5 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain GREB1 PF15782.5 OAJ26820.1 - 4.7 4.2 11.5 6.9 3.6 11.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GDI PF00996.18 OAJ26821.1 - 6.8e-31 107.3 0.0 7.1e-18 64.3 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor Rot1 PF10681.9 OAJ26822.1 - 2.7e-47 161.0 1.1 3.3e-47 160.7 1.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal BsuPI PF12690.7 OAJ26822.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Intracellular proteinase inhibitor DUF3140 PF11338.8 OAJ26823.1 - 4.1e-34 116.9 1.6 4.9e-34 116.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 OAJ26823.1 - 0.023 15.2 0.1 0.038 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Lipoprotein_Ltp PF07553.11 OAJ26823.1 - 0.031 14.5 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein DUF3673 PF12425.8 OAJ26823.1 - 0.085 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) DUF1640 PF07798.11 OAJ26824.1 - 1.3e-60 204.4 3.3 1.6e-60 204.1 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ParBc_2 PF08857.11 OAJ26824.1 - 0.094 12.8 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Putative ParB-like nuclease HALZ PF02183.18 OAJ26824.1 - 0.13 12.5 2.9 0.58 10.4 2.9 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF5082 PF16888.5 OAJ26824.1 - 1.7 8.9 4.5 6.5 7.1 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Zds_C PF08632.10 OAJ26825.1 - 1.2e-26 92.2 1.1 2.1e-26 91.4 1.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CLN3 PF02487.17 OAJ26825.1 - 1.5 7.8 4.8 4 6.4 4.8 1.7 1 0 0 1 1 1 0 CLN3 protein Serinc PF03348.15 OAJ26825.1 - 4.2 6.2 3.7 9.4 5.0 3.7 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Glyco_hydro_cc PF11790.8 OAJ26826.1 - 1.9e-49 168.4 0.7 2.5e-49 168.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TFIIA PF03153.13 OAJ26826.1 - 1.8 8.5 8.9 2.5 8.0 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 OAJ26826.1 - 5.6 6.3 9.0 7.5 5.9 9.0 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_M22 PF00814.25 OAJ26829.1 - 1.4e-66 225.0 0.1 1.8e-66 224.6 0.1 1.1 1 0 0 1 1 1 1 Glycoprotease family Adaptin_N PF01602.20 OAJ26830.1 - 1.2e-103 347.4 0.0 1.7e-103 347.0 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAJ26830.1 - 4.3e-51 173.0 0.0 8.1e-51 172.1 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAJ26830.1 - 5.3e-28 97.5 0.0 3.5e-27 94.8 0.0 2.4 1 1 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAJ26830.1 - 1.8e-19 69.9 0.4 8e-10 39.0 0.0 5.3 2 1 5 7 7 7 4 HEAT repeats Cnd1 PF12717.7 OAJ26830.1 - 3.9e-07 30.3 2.7 0.086 12.9 0.0 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ26830.1 - 0.0013 18.9 6.3 1.2 9.6 0.1 5.9 7 0 0 7 7 7 1 HEAT repeat HEAT_PBS PF03130.16 OAJ26830.1 - 0.025 15.2 3.4 27 5.8 0.1 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat WD40 PF00400.32 OAJ26831.1 - 1.4e-21 76.4 20.2 0.00018 22.2 0.1 7.4 6 2 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ26831.1 - 4.4e-08 33.3 2.5 0.0096 16.2 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ26831.1 - 0.0001 21.4 0.0 1.4 7.8 0.0 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Rtf2 PF04641.12 OAJ26832.1 - 0.00031 20.2 0.1 0.00072 19.0 0.1 1.6 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 OAJ26832.1 - 0.0034 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain MRG PF05712.13 OAJ26833.1 - 3e-59 199.7 0.0 4.6e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 OAJ26833.1 - 1.7e-10 40.6 0.0 3.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2951 PF11166.8 OAJ26833.1 - 0.52 10.5 2.1 1 9.6 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) MSA-2c PF12238.8 OAJ26833.1 - 6.2 6.8 23.5 0.037 14.0 1.1 3.3 3 0 0 3 3 3 0 Merozoite surface antigen 2c PCI PF01399.27 OAJ26834.1 - 1.5e-05 25.4 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain polyprenyl_synt PF00348.17 OAJ26835.1 - 7.3e-91 303.7 0.0 9.3e-91 303.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase VMA21 PF09446.10 OAJ26836.1 - 1.4e-12 47.6 9.8 2e-12 47.0 9.8 1.3 1 0 0 1 1 1 1 VMA21-like domain Abhydrolase_3 PF07859.13 OAJ26837.1 - 8.6e-18 65.0 0.0 3.8e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ26837.1 - 8.3e-10 38.1 0.0 7.6e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Steryl acetyl hydrolase SprA-related PF12118.8 OAJ26837.1 - 0.56 9.3 27.7 0.14 11.3 20.8 2.5 2 0 0 2 2 2 0 SprA-related family DDHD PF02862.17 OAJ26837.1 - 1.3 9.2 11.8 1.1 9.4 6.6 2.8 2 0 0 2 2 2 0 DDHD domain TERB2 PF15101.6 OAJ26837.1 - 1.9 8.5 17.4 0.23 11.5 11.0 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 OAJ26837.1 - 4 6.8 23.6 0.23 10.8 16.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Exonuc_VII_L PF02601.15 OAJ26837.1 - 4.3 6.8 12.1 9.4 5.7 12.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit RVT_1 PF00078.27 OAJ26838.1 - 1.7e-12 47.3 0.0 3.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ26838.1 - 3.6e-05 23.6 0.2 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.24 OAJ26838.1 - 0.034 14.3 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 RNase H Cauli_VI PF01693.16 OAJ26839.1 - 0.00071 19.8 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ank_4 PF13637.6 OAJ26840.1 - 5.8e-30 103.3 0.3 1.1e-13 51.4 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ26840.1 - 4.1e-28 97.8 0.0 1.2e-15 57.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ26840.1 - 5.1e-26 90.4 0.3 1.8e-09 37.6 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAJ26840.1 - 1.9e-24 85.0 0.3 5.9e-07 29.6 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 OAJ26840.1 - 5.8e-24 81.6 0.0 3.1e-06 27.1 0.0 5.6 7 0 0 7 7 7 4 Ankyrin repeat Cytochrom_C1 PF02167.15 OAJ26841.1 - 9.6e-100 332.8 0.0 1.2e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAJ26841.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAJ26841.1 - 0.047 14.8 0.1 0.24 12.6 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c CAP_GLY PF01302.25 OAJ26842.1 - 1.9e-26 91.9 0.8 3.2e-26 91.1 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAJ26842.1 - 1e-11 45.1 0.0 3.7e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain HMA PF00403.26 OAJ26844.1 - 6.5e-18 64.9 0.7 7.5e-18 64.7 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain CN_hydrolase PF00795.22 OAJ26847.1 - 2.1e-53 181.4 0.0 2.5e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L24e PF01246.20 OAJ26848.1 - 1.2e-32 111.9 5.1 2.8e-32 110.7 5.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Flu_M1 PF00598.19 OAJ26848.1 - 0.062 12.8 0.2 0.091 12.3 0.2 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) R2K_3 PF14243.6 OAJ26848.1 - 0.073 13.1 0.7 0.092 12.7 0.7 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Terminase_3C PF17288.2 OAJ26848.1 - 0.096 13.1 0.3 0.14 12.5 0.3 1.3 1 1 0 1 1 1 0 Terminase RNAseH like domain HAGH_C PF16123.5 OAJ26848.1 - 0.15 12.6 2.6 0.14 12.7 0.7 1.9 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus DUF2116 PF09889.9 OAJ26848.1 - 1.1 9.3 5.4 5 7.2 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.32 OAJ26849.1 - 4.3e-40 135.0 15.1 5.4e-08 33.4 0.1 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ26849.1 - 3.6e-15 56.0 0.6 9.6e-05 22.6 0.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 OAJ26849.1 - 1.2e-13 50.3 3.5 2.3e-13 49.5 3.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 OAJ26849.1 - 2.7e-06 26.9 0.0 0.00058 19.3 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 OAJ26849.1 - 0.00014 21.3 0.1 0.007 15.7 0.0 2.9 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 OAJ26849.1 - 0.00025 20.1 0.0 1.7 7.5 0.0 3.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ26849.1 - 0.088 11.4 0.0 2.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleopor_Nup85 PF07575.13 OAJ26850.1 - 8.3e-74 249.1 0.0 4.5e-39 134.5 0.0 2.7 2 1 0 2 2 2 2 Nup85 Nucleoporin RTBV_P46 PF06216.11 OAJ26851.1 - 1.6 7.6 5.9 0.91 8.3 0.6 2.4 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein PMT PF02366.18 OAJ26852.1 - 8.9e-78 261.2 16.2 1.6e-77 260.4 16.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ26852.1 - 1.6e-60 204.1 4.2 2.8e-60 203.4 0.4 2.6 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ26852.1 - 4.4e-12 46.2 0.4 1.1e-11 45.0 0.2 1.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 OAJ26852.1 - 2e-05 24.9 10.2 2e-05 24.9 10.2 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UPF0181 PF03701.14 OAJ26854.1 - 0.15 11.7 0.4 0.56 9.9 0.4 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Nop14 PF04147.12 OAJ26854.1 - 9 4.4 25.7 4.3 5.4 11.0 2.2 2 0 0 2 2 2 0 Nop14-like family NUDIX PF00293.28 OAJ26855.1 - 0.0018 18.3 2.0 1.6 8.7 0.1 2.9 2 1 1 3 3 3 2 NUDIX domain Milton PF12448.8 OAJ26855.1 - 0.15 12.2 4.6 0.39 10.8 4.6 1.6 1 0 0 1 1 1 0 Kinesin associated protein Sec7 PF01369.20 OAJ26856.1 - 8.2e-71 237.5 0.1 1.7e-70 236.4 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAJ26856.1 - 5.7e-45 153.1 5.3 5.7e-45 153.1 5.3 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAJ26856.1 - 1.5e-26 92.0 1.4 4.6e-25 87.3 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 OAJ26856.1 - 1.8e-20 73.3 4.7 7.4e-20 71.4 0.1 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RFC1 PF08519.12 OAJ26857.1 - 7.4e-51 172.4 0.1 2.8e-50 170.5 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAJ26857.1 - 2.9e-11 43.6 0.0 8.6e-11 42.1 0.0 1.9 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAJ26857.1 - 1.6e-09 38.3 0.0 4.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ26857.1 - 1e-06 28.8 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAJ26857.1 - 0.0017 18.8 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ26857.1 - 0.0024 18.1 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ26857.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OAJ26857.1 - 0.0029 17.4 0.2 0.046 13.5 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 OAJ26857.1 - 0.0035 17.1 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ26857.1 - 0.0039 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ26857.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 OAJ26857.1 - 0.02 15.2 0.0 0.084 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 OAJ26857.1 - 0.028 14.6 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAJ26857.1 - 0.069 13.0 0.5 0.22 11.4 0.1 2.0 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 OAJ26857.1 - 0.075 13.3 0.2 0.77 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OAJ26857.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ26857.1 - 0.13 12.2 0.0 0.78 9.6 0.0 2.2 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 OAJ26857.1 - 0.13 12.7 1.4 3.5 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OAJ26857.1 - 0.17 12.4 0.5 9.2 6.8 0.1 3.1 3 1 0 3 3 3 0 ABC transporter AAA_11 PF13086.6 OAJ26857.1 - 1.2 8.9 5.9 1.1 8.9 0.3 2.3 1 1 1 2 2 2 0 AAA domain KH_6 PF15985.5 OAJ26858.1 - 2.5e-08 34.2 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 OAJ26858.1 - 3.3e-07 30.0 0.2 6.6e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region FAD_binding_2 PF00890.24 OAJ26859.1 - 7.2e-33 114.3 0.0 1.2e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAJ26859.1 - 1.7e-22 79.3 0.2 5.1e-22 77.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Chorion_2 PF03964.15 OAJ26859.1 - 1.5 9.7 5.0 2.9 8.8 3.5 2.0 1 1 1 2 2 2 0 Chorion family 2 RVP_2 PF08284.11 OAJ26866.1 - 7.6e-11 41.9 0.1 1.2e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OAJ26866.1 - 5.8e-08 33.3 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ26866.1 - 2.6e-07 31.1 0.0 4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 OAJ26866.1 - 1e-05 25.2 0.3 1.5e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 OAJ26866.1 - 0.022 15.1 0.0 0.06 13.7 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 OAJ26866.1 - 0.23 11.3 0.0 0.73 9.6 0.0 1.8 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 OAJ26868.1 - 2.6e-11 43.6 0.2 6.2e-11 42.4 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ26868.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 OAJ26868.1 - 0.082 13.0 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ26868.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RNase_H PF00075.24 OAJ26869.1 - 1.6e-13 51.1 0.1 3.2e-13 50.1 0.1 1.5 1 1 0 1 1 1 1 RNase H CopK PF11525.8 OAJ26869.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein K RVT_1 PF00078.27 OAJ26870.1 - 3e-27 95.6 0.0 4.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ26870.1 - 1.3e-18 66.9 0.0 2.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ26870.1 - 2.6e-09 37.0 0.7 8.1e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S27e PF01667.17 OAJ26870.1 - 2.1 8.2 7.1 3.3 7.5 3.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S27 Pkinase PF00069.25 OAJ26871.1 - 0.00046 19.6 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ26871.1 - 0.007 15.7 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GMC_oxred_N PF00732.19 OAJ26872.1 - 0.13 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Tannase PF07519.11 OAJ26873.1 - 1.9e-45 155.7 0.0 8.2e-38 130.5 0.1 2.6 1 1 1 2 2 2 2 Tannase and feruloyl esterase WD40 PF00400.32 OAJ26873.1 - 2.7e-37 126.1 13.7 2.2e-07 31.4 0.4 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 OAJ26873.1 - 0.025 13.2 0.2 6.5 5.3 0.0 3.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 nos_propeller_2 PF18793.1 OAJ26873.1 - 0.12 12.8 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat 2 TMEM141 PF15110.6 OAJ26874.1 - 1.4 9.5 3.3 13 6.5 0.1 2.7 2 1 0 2 2 2 0 TMEM141 protein family PepSY_TM PF03929.16 OAJ26874.1 - 8.9 5.9 11.5 1.9 8.1 5.2 2.6 3 0 0 3 3 3 0 PepSY-associated TM region MFS_1 PF07690.16 OAJ26876.1 - 6e-29 101.1 31.0 7.9e-29 100.7 31.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAJ26876.1 - 1.2 7.9 13.0 0.32 9.8 8.1 1.9 1 1 0 2 2 2 0 MFS_1 like family SNF2_N PF00176.23 OAJ26878.1 - 1.3e-57 195.1 15.6 3.1e-56 190.6 10.1 3.7 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ26878.1 - 3.6e-15 56.2 0.0 7.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Trypan_PARP PF05887.11 OAJ26878.1 - 5.2 7.1 14.0 5.4 7.0 0.6 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Mcm10 PF09332.11 OAJ26879.1 - 0.19 11.1 1.8 0.21 11.0 1.8 1.0 1 0 0 1 1 1 0 Mcm10 replication factor DUF2561 PF10812.8 OAJ26879.1 - 1.1 9.3 3.3 1.4 8.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) RmlD_sub_bind PF04321.17 OAJ26880.1 - 0.039 13.1 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DHHW PF14286.6 OAJ26880.1 - 0.11 11.8 1.6 0.12 11.6 1.6 1.1 1 0 0 1 1 1 0 DHHW protein SR-25 PF10500.9 OAJ26880.1 - 0.26 10.8 16.9 0.34 10.5 16.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 OAJ26880.1 - 1.5 7.3 7.7 1.9 7.0 7.7 1.0 1 0 0 1 1 1 0 Macoilin family SIP1 PF04938.12 OAJ26881.1 - 7.2e-25 88.0 0.1 1.4e-24 87.1 0.1 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pex14_N PF04695.13 OAJ26881.1 - 7 7.3 13.8 2.6 8.7 6.2 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3HC4_3 PF13920.6 OAJ26882.1 - 0.0011 18.8 7.2 0.0023 17.7 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ26882.1 - 0.64 10.0 9.4 1.4 8.9 9.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ26882.1 - 5 7.2 7.1 11 6.2 7.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ26882.1 - 5.1 7.1 10.4 11 5.9 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ26882.1 - 6.5 7.2 9.7 15 6.0 9.7 1.6 1 0 0 1 1 1 0 Ring finger domain Formyl_trans_N PF00551.19 OAJ26883.1 - 6.2e-38 130.3 0.0 2.8e-35 121.7 0.0 2.4 1 1 0 1 1 1 1 Formyl transferase MAS20 PF02064.15 OAJ26883.1 - 3.5e-23 82.1 0.2 5.7e-23 81.4 0.2 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor FUSC PF04632.12 OAJ26883.1 - 0.89 8.0 6.4 1.3 7.5 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Myosin_head PF00063.21 OAJ26884.1 - 5.8e-265 880.7 0.0 1.3e-264 879.5 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 OAJ26884.1 - 2e-07 30.7 0.4 4.8e-07 29.5 0.4 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.6 OAJ26884.1 - 0.1 12.9 0.1 0.1 12.9 0.1 3.3 3 2 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OAJ26884.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.5 3 1 1 4 4 4 0 AAA domain IQ PF00612.27 OAJ26884.1 - 0.26 11.2 2.8 0.38 10.7 0.5 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif Aconitase PF00330.20 OAJ26885.1 - 1.4e-160 535.3 0.0 1.7e-160 535.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ26885.1 - 8.3e-42 142.6 0.0 1.6e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SKA1 PF07160.12 OAJ26886.1 - 0.023 14.6 0.3 0.023 14.6 0.3 2.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF3829 PF12889.7 OAJ26886.1 - 0.025 14.0 1.5 2.1 7.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Syntaxin PF00804.25 OAJ26886.1 - 0.061 13.0 3.5 0.36 10.5 0.1 2.4 2 0 0 2 2 2 0 Syntaxin HLH PF00010.26 OAJ26887.1 - 7.7e-05 22.6 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain EPL1 PF10513.9 OAJ26887.1 - 0.054 13.9 8.8 0.26 11.7 1.5 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like MAS20 PF02064.15 OAJ26887.1 - 0.5 10.5 6.6 7.1 6.7 0.2 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor DUF2828 PF11443.8 OAJ26887.1 - 0.64 8.0 5.6 0.87 7.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SUIM_assoc PF16619.5 OAJ26887.1 - 0.77 9.9 32.4 0.045 13.8 5.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 OAJ26887.1 - 0.83 9.2 28.6 0.47 10.0 4.7 2.2 2 0 0 2 2 2 0 Spt20 family RBM39linker PF15519.6 OAJ26887.1 - 6.4 7.9 9.0 5.3 8.2 2.2 2.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Neur_chan_memb PF02932.16 OAJ26887.1 - 9.8 6.1 7.9 22 5.0 7.9 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RT_RNaseH PF17917.1 OAJ26889.1 - 1.6e-35 121.5 0.0 3.4e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ26889.1 - 1.2e-31 108.7 0.0 3.6e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ26889.1 - 2.1e-22 78.9 0.0 5.4e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ26889.1 - 6e-17 61.9 0.0 9.4e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 OAJ26889.1 - 1.2e-15 57.1 0.1 2.4e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 OAJ26889.1 - 1.6e-13 50.9 0.0 3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ26889.1 - 1.4e-07 31.6 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF1796 PF08795.10 OAJ26889.1 - 0.0092 16.0 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Pga1 PF10333.9 OAJ26891.1 - 0.093 12.6 0.7 15 5.4 0.3 2.7 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator Shisa PF13908.6 OAJ26891.1 - 9.8 6.4 6.6 5 7.3 0.9 3.0 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Ribosomal_L7Ae PF01248.26 OAJ26892.1 - 9.6e-22 76.5 0.3 1.5e-21 76.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAJ26892.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 ATPase_2 PF01637.18 OAJ26892.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RhoGEF PF00621.20 OAJ26893.1 - 6.1e-17 62.4 0.1 1.9e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Cu-oxidase_3 PF07732.15 OAJ26895.1 - 6.6e-38 129.4 2.7 6.6e-38 129.4 2.7 3.3 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ26895.1 - 2.9e-35 121.0 8.8 5.2e-33 113.7 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ26895.1 - 5.5e-30 104.6 0.3 4.3e-28 98.4 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase N_BRCA1_IG PF16158.5 OAJ26895.1 - 0.0015 19.2 0.0 0.0059 17.3 0.0 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PBP1_TM PF14812.6 OAJ26896.1 - 0.028 14.8 7.6 0.028 14.8 7.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 OAJ26896.1 - 0.032 14.0 4.8 0.054 13.2 4.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 OAJ26896.1 - 0.045 13.2 6.3 0.086 12.3 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.14 OAJ26896.1 - 0.17 10.1 0.4 0.2 9.9 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ26896.1 - 0.28 9.3 4.2 0.39 8.8 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OAJ26896.1 - 0.36 10.8 1.9 0.7 9.9 1.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 OAJ26896.1 - 0.45 9.8 9.8 0.023 14.0 4.3 1.6 2 0 0 2 2 2 0 NOA36 protein PGA2 PF07543.12 OAJ26896.1 - 0.77 9.7 4.7 1.6 8.7 4.7 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 GCIP PF13324.6 OAJ26896.1 - 0.85 9.2 3.2 6.6 6.3 2.1 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 OAJ26896.1 - 3.7 8.0 15.0 8.1 6.9 15.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cu-oxidase_3 PF07732.15 OAJ26897.1 - 1.4e-37 128.3 6.5 9.1e-36 122.5 3.4 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ26897.1 - 1.2e-29 102.8 5.7 6.8e-25 87.4 0.0 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 OAJ26897.1 - 4.5e-24 85.4 0.0 1.1e-23 84.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase DUF5060 PF16586.5 OAJ26897.1 - 0.017 15.5 0.1 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) PIG-U PF06728.13 OAJ26898.1 - 5e-87 292.4 14.5 6.1e-87 292.1 14.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Chromo_shadow PF01393.19 OAJ26898.1 - 1.7e-12 47.3 0.0 7e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 OAJ26898.1 - 2.5e-07 30.5 3.4 4.3e-07 29.7 3.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mannosyl_trans PF05007.13 OAJ26898.1 - 0.0044 16.9 4.5 0.0095 15.8 4.5 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) SWIRM-assoc_2 PF16496.5 OAJ26898.1 - 0.044 12.7 5.2 0.061 12.2 5.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DEAD PF00270.29 OAJ26899.1 - 1.2e-31 109.8 0.0 1.6e-30 106.2 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26899.1 - 9.6e-16 58.1 0.1 8.3e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ26899.1 - 0.009 16.0 0.0 0.64 10.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_hydro_35 PF01301.19 OAJ26900.1 - 4.7e-74 249.9 0.0 8.3e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAJ26900.1 - 9e-40 135.8 0.1 8.7e-25 87.5 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAJ26900.1 - 9.1e-25 87.5 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAJ26900.1 - 1.1e-07 31.3 0.0 2.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 OAJ26900.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 OAJ26901.1 - 8.6e-16 56.7 26.0 0.013 15.5 0.1 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26901.1 - 8e-15 54.0 12.5 2.3e-05 24.0 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ26901.1 - 5.1e-10 38.9 0.8 0.039 13.6 0.0 6.3 5 2 2 7 7 7 2 TPR repeat TPR_14 PF13428.6 OAJ26901.1 - 6.7e-10 39.0 39.6 0.021 15.6 0.2 9.9 6 1 4 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ26901.1 - 7.2e-09 36.0 29.8 4.1e-07 30.4 0.6 7.4 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ26901.1 - 1.1e-08 34.8 0.1 0.51 10.8 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ26901.1 - 1.3e-07 31.3 10.4 0.16 12.2 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ26901.1 - 4.8e-07 30.3 5.7 0.0025 18.4 0.3 8.1 6 1 4 10 10 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ26901.1 - 3.5e-05 24.0 25.1 0.012 15.9 1.1 6.5 4 2 3 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ26901.1 - 0.0002 21.5 6.7 2.3 8.5 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ26901.1 - 0.0013 18.9 0.8 0.0013 18.9 0.8 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ26901.1 - 0.017 15.1 15.4 0.69 10.1 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat CDC45 PF02724.14 OAJ26901.1 - 0.041 12.2 21.2 0.077 11.3 21.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ26901.1 - 0.14 10.4 27.5 0.2 9.8 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family SNAP PF14938.6 OAJ26901.1 - 1.3 8.4 7.0 4.3 6.7 1.7 3.0 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP DUF2457 PF10446.9 OAJ26901.1 - 1.6 7.8 33.8 4.1 6.4 33.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.10 OAJ26901.1 - 1.8 8.8 7.7 4.8 7.5 7.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 OAJ26901.1 - 2.6 7.4 32.1 5.3 6.4 32.1 1.4 1 0 0 1 1 1 0 SDA1 Peptidase_M41 PF01434.18 OAJ26907.1 - 6.4e-62 208.8 0.2 6.4e-62 208.8 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 OAJ26907.1 - 3.3e-42 144.0 0.0 8.4e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ26907.1 - 3.6e-11 42.7 0.1 9.4e-11 41.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAJ26907.1 - 2.5e-10 40.7 1.2 4.8e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.6 OAJ26907.1 - 0.0025 18.1 0.1 0.49 10.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAJ26907.1 - 0.0052 16.0 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OAJ26907.1 - 0.006 17.0 0.0 0.2 12.0 0.1 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ26907.1 - 0.015 15.3 0.1 0.11 12.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ26907.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 OAJ26907.1 - 0.032 14.0 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OAJ26907.1 - 0.093 12.3 0.5 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Apt1 PF10351.9 OAJ26907.1 - 3.8 6.2 8.6 5.6 5.7 8.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Collagen PF01391.18 OAJ26908.1 - 6.3e-24 83.5 152.3 5.4e-07 29.3 26.2 5.4 1 1 3 4 4 4 3 Collagen triple helix repeat (20 copies) CDC45 PF02724.14 OAJ26909.1 - 0.14 10.4 3.4 0.17 10.2 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ26909.1 - 0.64 8.1 10.8 0.84 7.7 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi HEAT_2 PF13646.6 OAJ26910.1 - 6.7e-20 71.3 4.6 1e-12 48.2 0.4 4.8 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 OAJ26910.1 - 3.1e-12 45.6 2.9 0.063 13.6 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 OAJ26910.1 - 9e-11 41.4 8.4 0.012 16.3 0.0 7.4 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat Arm PF00514.23 OAJ26910.1 - 0.0011 18.9 0.0 0.39 10.8 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ26910.1 - 1.1 9.8 11.6 1.9 9.1 0.1 4.6 4 2 0 5 5 5 0 HEAT-like repeat ABC_membrane PF00664.23 OAJ26911.1 - 9.6e-45 153.3 38.0 1e-28 100.7 16.4 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ26911.1 - 1.7e-40 138.7 0.0 7e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ26911.1 - 7.6e-08 32.1 4.6 0.0066 15.9 0.1 4.5 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ26911.1 - 0.00017 22.2 0.0 0.72 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAJ26911.1 - 0.00039 20.1 0.4 0.8 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ26911.1 - 0.0018 18.6 0.9 1.8 8.8 0.1 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAJ26911.1 - 0.014 15.5 1.6 0.015 15.4 0.2 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 OAJ26911.1 - 0.025 15.0 0.1 0.26 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OAJ26911.1 - 0.026 14.5 0.6 0.27 11.2 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_24 PF13479.6 OAJ26911.1 - 0.035 13.8 0.3 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ26911.1 - 0.092 12.3 0.4 0.72 9.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAJ26911.1 - 0.11 12.4 0.2 22 4.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 OAJ26911.1 - 0.14 12.6 0.2 4.5 7.7 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.18 OAJ26912.1 - 1.5e-05 25.0 7.3 3e-05 24.1 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DMAP1 PF05499.12 OAJ26913.1 - 0.31 10.9 3.6 0.21 11.4 1.7 1.6 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF4164 PF13747.6 OAJ26914.1 - 0.0057 16.9 4.5 0.031 14.5 4.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) Apolipoprotein PF01442.18 OAJ26914.1 - 0.0076 16.1 4.3 0.0097 15.8 4.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FdhE PF04216.12 OAJ26914.1 - 0.038 13.9 0.6 0.04 13.8 0.6 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF1043 PF06295.12 OAJ26914.1 - 0.046 13.7 1.1 0.061 13.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Dzip-like_N PF13815.6 OAJ26914.1 - 0.053 13.5 0.6 0.062 13.3 0.6 1.2 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Exotox-A_bind PF09101.10 OAJ26914.1 - 0.12 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding DUF883 PF05957.13 OAJ26914.1 - 1 10.0 7.3 0.83 10.3 1.5 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Histone_H2A_C PF16211.5 OAJ26915.1 - 2.1e-18 65.7 0.8 4.8e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ26915.1 - 2.1e-13 50.8 0.0 2.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HhH-GPD PF00730.25 OAJ26916.1 - 1.4e-11 44.8 0.0 3.9e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ26916.1 - 0.079 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 OAJ26916.1 - 0.17 12.0 0.0 0.62 10.2 0.0 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix motif PLA2_B PF01735.18 OAJ26917.1 - 2.7e-12 45.9 0.0 1.6e-06 26.8 1.5 2.6 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Med3 PF11593.8 OAJ26917.1 - 8.8 5.4 11.3 12 4.9 11.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Metallophos_2 PF12850.7 OAJ26918.1 - 9.7e-18 64.9 0.1 1.6e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OAJ26918.1 - 0.00093 19.7 0.8 0.13 12.7 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase BUD22 PF09073.10 OAJ26918.1 - 1.4 8.2 22.6 1.8 7.8 22.6 1.0 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 OAJ26918.1 - 3 6.3 18.7 4.1 5.9 18.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Epimerase PF01370.21 OAJ26920.1 - 1.4e-05 24.7 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAJ26920.1 - 0.00089 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAJ26920.1 - 0.0031 17.8 0.0 0.0064 16.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 OAJ26920.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Glyco_tran_WecB PF03808.13 OAJ26920.1 - 0.03 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family GDP_Man_Dehyd PF16363.5 OAJ26920.1 - 0.094 12.1 0.0 1 8.7 0.0 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 OAJ26920.1 - 0.15 11.9 0.2 0.38 10.6 0.0 1.7 1 1 1 2 2 2 0 KR domain PDZ_5 PF17817.1 OAJ26922.1 - 0.075 13.3 0.1 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 PDZ domain Ycf9 PF01737.17 OAJ26923.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 YCF9 ANAPC3 PF12895.7 OAJ26924.1 - 7.7e-06 26.1 6.1 4.6 7.5 0.1 6.4 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OAJ26924.1 - 0.00049 19.9 16.4 3.9 7.5 0.0 6.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ26924.1 - 0.00075 19.7 37.1 0.083 13.2 3.8 7.4 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ26924.1 - 0.011 16.5 28.1 2.5 9.2 0.3 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ26924.1 - 0.017 15.2 28.4 3 8.2 0.5 8.7 10 0 0 10 10 10 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ26924.1 - 0.022 14.8 8.6 4.8 7.3 0.3 5.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 OAJ26924.1 - 0.038 14.2 8.3 45 4.6 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26924.1 - 0.54 10.2 11.8 2.5 8.1 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ26924.1 - 1.7 9.2 25.8 5.1 7.7 4.9 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat NOA36 PF06524.12 OAJ26924.1 - 9.3 5.5 7.2 20 4.4 7.2 1.5 1 0 0 1 1 1 0 NOA36 protein IMP_cyclohyd PF07826.11 OAJ26925.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein partial_CstF PF15861.5 OAJ26925.1 - 0.35 10.7 8.5 3.5 7.5 0.3 3.3 3 0 0 3 3 3 0 Partial cleavage stimulation factor domain BUD22 PF09073.10 OAJ26927.1 - 1.9 7.7 27.8 2.3 7.5 9.3 3.4 3 0 0 3 3 3 0 BUD22 ARID PF01388.21 OAJ26928.1 - 6.4e-05 23.6 2.8 0.013 16.2 0.0 3.4 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain Zip PF02535.22 OAJ26928.1 - 0.067 12.4 13.4 0.26 10.5 0.6 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF966 PF06136.13 OAJ26928.1 - 0.19 11.5 17.2 0.96 9.1 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) MMR1 PF08505.10 OAJ26928.1 - 0.42 10.8 31.7 1.5 9.1 7.4 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SRP-alpha_N PF04086.13 OAJ26928.1 - 1.5 8.7 28.1 0.064 13.2 16.4 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CCSAP PF15748.5 OAJ26928.1 - 8.8 6.4 28.7 4.1 7.5 13.5 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated PHD PF00628.29 OAJ26929.1 - 2.9e-13 49.5 20.7 1.6e-08 34.3 9.0 2.8 3 0 0 3 3 3 2 PHD-finger DUF1360 PF07098.11 OAJ26929.1 - 0.79 9.7 2.4 1.1 9.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) zf-PHD-like PF15446.6 OAJ26929.1 - 1.5 8.4 5.4 0.41 10.2 2.1 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_transf_28 PF03033.20 OAJ26930.1 - 3.9e-24 85.3 0.0 7.6e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAJ26930.1 - 3.9e-05 23.5 0.0 0.12 12.3 0.0 2.9 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.18 OAJ26930.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 OAJ26930.1 - 0.0039 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Rod_cone_degen PF15201.6 OAJ26930.1 - 0.9 9.7 4.0 1 9.5 0.4 3.2 2 0 0 2 2 2 0 Progressive rod-cone degeneration Mobilization_B PF17511.2 OAJ26930.1 - 4.1 7.8 5.4 15 5.9 5.4 1.9 1 0 0 1 1 1 0 Mobilization protein B SUZ PF12752.7 OAJ26931.1 - 1.1e-10 42.1 1.8 1.1e-10 42.1 1.8 3.1 3 1 0 3 3 3 1 SUZ domain TEX19 PF15553.6 OAJ26931.1 - 3 7.8 4.4 3.1 7.8 2.8 1.8 1 1 0 2 2 2 0 Testis-expressed protein 19 p450 PF00067.22 OAJ26932.1 - 2.1e-57 194.9 0.0 4.1e-57 194.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Promethin PF16015.5 OAJ26933.1 - 0.82 9.6 7.6 3 7.8 0.2 3.4 3 0 0 3 3 3 0 Promethin Glyco_hydro_cc PF11790.8 OAJ26934.1 - 9e-38 130.2 0.1 1.2e-37 129.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Neur_chan_memb PF02932.16 OAJ26934.1 - 3.5 7.6 4.4 6 6.8 4.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 OAJ26934.1 - 4 5.9 13.2 5.9 5.3 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Connexin PF00029.19 OAJ26934.1 - 4.9 6.8 6.6 8.4 6.1 6.6 1.4 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 OAJ26934.1 - 7.3 4.4 6.6 11 3.7 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 OAJ26934.1 - 9 5.2 9.1 5 6.0 4.0 2.0 2 0 0 2 2 2 0 Solute carrier family 12 RhoGAP PF00620.27 OAJ26935.1 - 1.5e-35 122.2 0.0 2.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DPBB_1 PF03330.18 OAJ26936.1 - 4.8e-09 36.4 0.1 8.8e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase PBP PF01161.20 OAJ26937.1 - 5.7e-16 59.0 0.1 1.1e-15 58.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.32 OAJ26939.1 - 9.1e-54 178.2 16.0 2.4e-11 44.0 0.4 8.6 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ26939.1 - 6.8e-14 51.9 0.9 9.8e-06 25.8 0.1 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ26939.1 - 1.6e-09 37.0 13.7 0.011 14.4 0.2 5.5 3 1 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ26939.1 - 0.00027 19.8 0.5 5 5.8 0.0 4.0 2 1 2 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.16 OAJ26939.1 - 0.028 13.0 0.0 1.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 OAJ26939.1 - 0.051 13.5 0.0 9.4 6.1 0.1 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OAJ26939.1 - 0.24 9.7 0.0 1.1 7.5 0.0 2.0 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Enolase_C PF00113.22 OAJ26940.1 - 2.1e-141 470.4 0.2 2.7e-141 470.1 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAJ26940.1 - 4.1e-57 192.0 0.1 7.5e-57 191.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAJ26940.1 - 9.1e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAJ26940.1 - 0.008 15.4 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus ANAPC10 PF03256.16 OAJ26941.1 - 5.2e-45 153.3 0.0 1e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) XRCC1_N PF01834.16 OAJ26941.1 - 0.055 13.5 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain Spt5_N PF11942.8 OAJ26941.1 - 3.8 8.6 11.4 0.13 13.3 2.2 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SUIM_assoc PF16619.5 OAJ26941.1 - 8 6.6 15.5 24 5.1 15.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Chitin_synth_2 PF03142.15 OAJ26942.1 - 8.6e-236 783.6 0.2 8.6e-236 783.6 0.2 1.8 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 OAJ26942.1 - 1.4e-130 436.6 0.0 6.1e-117 391.6 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 OAJ26942.1 - 1.9e-15 56.5 0.2 8.7e-14 51.2 0.0 3.3 4 0 0 4 4 4 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAJ26942.1 - 8.6e-14 51.9 3.1 1.3e-13 51.3 1.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 OAJ26942.1 - 2.8e-11 43.4 0.5 3.6e-07 30.2 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAJ26942.1 - 3.5e-08 33.6 0.0 6.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAJ26942.1 - 0.0014 18.5 0.0 0.38 10.5 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 DEAD PF00270.29 OAJ26942.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OAJ26942.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain KDZ PF18758.1 OAJ26949.1 - 1.9e-46 158.5 0.0 3e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ26949.1 - 0.00026 21.1 0.0 0.00064 19.8 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ26949.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CMAS PF02353.20 OAJ26951.1 - 1e-33 116.8 0.4 4.5e-33 114.7 0.4 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ26951.1 - 5e-12 46.4 0.0 1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ26951.1 - 8e-12 45.7 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ26951.1 - 3.5e-09 36.6 0.0 1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ26951.1 - 5.6e-06 26.3 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ26951.1 - 1.2e-05 25.9 0.0 2.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ26951.1 - 2.8e-05 23.7 0.0 6.1e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAJ26951.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 OAJ26951.1 - 0.0046 16.4 0.1 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 OAJ26951.1 - 0.0047 16.6 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F GidB PF02527.15 OAJ26951.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MetW PF07021.12 OAJ26951.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pmp3 PF01679.17 OAJ26952.1 - 9.8e-23 80.1 10.3 1.2e-22 79.9 10.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ada3 PF10198.9 OAJ26953.1 - 7e-26 90.9 0.4 5.7e-25 88.0 0.0 2.6 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 Histone_H2A_C PF16211.5 OAJ26955.1 - 1.7e-18 66.1 0.7 3.4e-18 65.1 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ26955.1 - 1.3e-16 61.1 0.0 1.8e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ26955.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAP PF07174.11 OAJ26956.1 - 0.025 14.1 2.3 0.031 13.8 2.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GbpA_2 PF18416.1 OAJ26957.1 - 0.11 12.9 0.2 0.5 10.7 0.1 2.0 2 0 0 2 2 2 0 N-acetylglucosamine binding protein domain 2 Pex14_N PF04695.13 OAJ26957.1 - 0.25 12.0 5.4 0.37 11.4 5.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.7 OAJ26958.1 - 2.3e-09 37.0 0.3 5.4e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ26958.1 - 1.8e-07 30.8 0.1 5.1e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain WH1 PF00568.23 OAJ26959.1 - 7.2e-13 48.4 0.0 3.1e-12 46.4 0.0 2.0 2 1 0 2 2 2 1 WH1 domain PBD PF00786.28 OAJ26959.1 - 5.8e-09 36.2 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 OAJ26959.1 - 0.0012 18.6 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 WH2 motif EFG_C PF00679.24 OAJ26959.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G C-terminus Plasmodium_Vir PF05795.11 OAJ26959.1 - 0.65 9.3 2.1 1.2 8.5 2.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3583 PF12126.8 OAJ26959.1 - 5 6.5 5.4 9.5 5.6 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Lactamase_B_2 PF12706.7 OAJ26960.1 - 1.9e-09 37.3 0.1 0.0001 21.9 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OAJ26960.1 - 2.5e-09 36.7 0.0 5.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OAJ26960.1 - 0.014 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily UPF0160 PF03690.13 OAJ26961.1 - 1.1e-130 435.9 0.0 2.1e-130 435.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RNase_H2-Ydr279 PF09468.10 OAJ26961.1 - 4.9e-10 39.8 0.0 7.8e-09 35.9 0.0 2.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAJ26961.1 - 6.5e-06 26.3 0.0 5.5e-05 23.3 0.0 2.6 1 1 0 1 1 1 1 Ydr279p protein triple barrel domain DUF4841 PF16129.5 OAJ26961.1 - 0.0071 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4841) DUF572 PF04502.13 OAJ26961.1 - 0.09 12.4 1.7 0.16 11.6 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-BED PF02892.15 OAJ26962.1 - 0.033 14.2 2.6 0.072 13.1 2.6 1.5 1 0 0 1 1 1 0 BED zinc finger PRCC PF10253.9 OAJ26963.1 - 3.5 8.4 13.2 0.045 14.5 5.6 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4207 PF13904.6 OAJ26964.1 - 0.066 12.9 4.8 0.1 12.2 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) BUD22 PF09073.10 OAJ26966.1 - 3 7.1 6.6 4.9 6.4 6.6 1.2 1 0 0 1 1 1 0 BUD22 Med3 PF11593.8 OAJ26966.1 - 6.1 5.9 12.3 9.8 5.2 12.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DEAD PF00270.29 OAJ26969.1 - 8.9e-10 38.6 0.0 2.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26969.1 - 2.4e-08 34.3 0.0 8.9e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ26969.1 - 0.0063 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit YpjP PF14005.6 OAJ26969.1 - 0.61 10.1 2.0 1.5 8.9 2.0 1.6 1 0 0 1 1 1 0 YpjP-like protein Hid1 PF12722.7 OAJ26969.1 - 1.3 7.0 4.0 1.9 6.6 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PRIMA1 PF16101.5 OAJ26969.1 - 1.4 9.0 4.8 4.1 7.5 4.8 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MFS_1 PF07690.16 OAJ26970.1 - 2.4e-17 62.9 46.0 2.4e-17 62.9 46.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ26970.1 - 0.0014 17.0 2.6 0.0087 14.4 0.0 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 OAJ26972.1 - 1.7 8.9 5.9 6.4 7.0 6.0 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain JAB PF01398.21 OAJ26973.1 - 2.7e-28 98.3 0.2 4.3e-28 97.7 0.2 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAJ26973.1 - 5.9e-16 59.2 2.4 1e-13 52.0 2.4 2.7 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAJ26973.1 - 7.4e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Rrn6 PF10214.9 OAJ26973.1 - 0.048 12.2 1.3 0.067 11.7 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UPF0172 PF03665.13 OAJ26973.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) EVC2_like PF12297.8 OAJ26973.1 - 0.28 9.8 0.4 0.4 9.3 0.4 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein TFIIF_alpha PF05793.12 OAJ26973.1 - 1.4 7.4 7.3 2 6.9 7.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt20 PF12090.8 OAJ26975.1 - 0.99 9.0 5.2 22 4.6 4.1 2.3 2 0 0 2 2 2 0 Spt20 family CRIM PF16978.5 OAJ26976.1 - 4.5e-30 104.7 0.0 6.7e-27 94.4 0.0 2.8 3 0 0 3 3 3 2 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAJ26976.1 - 6.2e-22 78.0 0.0 9.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology MttA_Hcf106 PF02416.16 OAJ26977.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family B56 PF01603.20 OAJ26979.1 - 6.1e-192 638.1 2.8 7.2e-192 637.9 2.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Hat1_N PF10394.9 OAJ26980.1 - 1.2e-43 149.1 0.0 3e-43 147.8 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 OAJ26980.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ26980.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 OAJ26980.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family SWIB PF02201.18 OAJ26981.1 - 1.2e-21 76.4 0.1 4.6e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain HTH_20 PF12840.7 OAJ26981.1 - 0.068 13.2 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Sec66 PF09802.9 OAJ26982.1 - 2.8e-52 176.9 0.2 4.6e-52 176.2 0.2 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 PPP4R2 PF09184.11 OAJ26982.1 - 0.036 13.6 7.1 0.043 13.4 7.1 1.2 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.18 OAJ26982.1 - 0.048 13.6 4.6 0.072 13.0 4.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CDC27 PF09507.10 OAJ26982.1 - 0.16 11.3 12.8 0.2 11.0 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_S25 PF03297.15 OAJ26982.1 - 4.7 7.5 9.6 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 S25 ribosomal protein AMP-binding PF00501.28 OAJ26983.1 - 2.6e-71 240.4 0.0 3.6e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ26983.1 - 6.4e-65 218.9 0.0 9.5e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 OAJ26983.1 - 3.2e-12 45.9 0.0 4.8e-05 22.2 0.0 3.2 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.25 OAJ26983.1 - 2.4e-11 43.8 0.0 6.3e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAJ26983.1 - 7.2e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 OAJ26983.1 - 0.00014 22.8 0.0 0.00095 20.1 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OAJ26983.1 - 0.00097 18.2 0.0 0.03 13.3 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAJ26983.1 - 0.013 14.6 0.0 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PTPlike_phytase PF14566.6 OAJ26984.1 - 3.5e-05 24.0 0.0 8.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 OAJ26984.1 - 0.0003 20.6 0.0 0.0006 19.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAJ26984.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2950 PF11453.8 OAJ26984.1 - 0.022 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Y_phosphatase PF00102.27 OAJ26984.1 - 0.041 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Serglycin PF04360.12 OAJ26985.1 - 3.7 7.5 9.8 9.2 6.2 9.8 1.7 1 0 0 1 1 1 0 Serglycin SPX PF03105.19 OAJ26985.1 - 7 6.4 9.4 8.3 6.2 9.4 1.1 1 0 0 1 1 1 0 SPX domain Asp PF00026.23 OAJ26986.1 - 6.2e-61 206.5 0.7 7.7e-61 206.2 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ26986.1 - 1.2e-12 48.4 4.2 1.4e-11 44.9 4.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal EF-hand_7 PF13499.6 OAJ26987.1 - 1.1e-28 99.4 10.8 8.5e-15 55.0 4.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAJ26987.1 - 7.4e-28 94.0 13.1 3.1e-08 32.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OAJ26987.1 - 1.1e-22 78.0 8.9 4.7e-07 29.2 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ26987.1 - 6.4e-19 67.5 11.3 2.3e-08 33.8 1.9 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OAJ26987.1 - 6.8e-15 53.8 10.2 5.6e-05 22.4 1.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OAJ26987.1 - 2.1e-12 47.2 0.5 1.5e-05 25.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAJ26987.1 - 2.6e-06 27.3 2.0 0.044 13.7 0.7 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OAJ26987.1 - 0.00015 21.7 0.5 0.15 12.0 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 OAJ26987.1 - 0.0056 17.0 1.3 1.7 9.0 0.3 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OAJ26987.1 - 0.046 14.1 1.6 0.76 10.2 0.5 2.3 2 1 0 2 2 2 0 EF-hand domain PhetRS_B1 PF18262.1 OAJ26987.1 - 0.11 12.8 3.0 0.14 12.4 1.4 1.9 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Dockerin_1 PF00404.18 OAJ26987.1 - 0.13 12.4 1.6 5.4 7.3 0.6 2.5 2 0 0 2 2 2 0 Dockerin type I domain SHOCT PF09851.9 OAJ26987.1 - 9.4 6.1 7.2 0.7 9.7 0.5 2.8 3 0 0 3 3 3 0 Short C-terminal domain His_biosynth PF00977.21 OAJ26988.1 - 6.5e-40 137.0 0.0 2.2e-24 86.2 0.0 3.0 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 OAJ26988.1 - 9.4e-17 61.4 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAJ26988.1 - 1.9e-07 30.9 0.0 4.2e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 OAJ26988.1 - 1.1e-06 28.6 0.0 5.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 OAJ26988.1 - 0.091 12.5 0.4 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Kei1 PF08552.11 OAJ26989.1 - 1.2e-50 172.0 1.4 1.5e-50 171.7 1.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Abhydrolase_6 PF12697.7 OAJ26990.1 - 3.9e-22 80.0 0.8 6.3e-22 79.3 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ26990.1 - 2.3e-09 36.9 0.0 4.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ26990.1 - 5.1e-07 29.6 0.0 2.2e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ26990.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAJ26990.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MFS_1 PF07690.16 OAJ26991.1 - 2.8e-18 66.0 10.9 2.8e-18 66.0 10.9 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily UQ_con PF00179.26 OAJ26992.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.29 OAJ26998.1 - 7.3e-46 156.1 0.0 2.1e-45 154.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26998.1 - 1.6e-27 96.0 0.0 1.5e-26 92.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ26998.1 - 0.00026 21.0 0.0 0.00072 19.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ26998.1 - 0.016 14.6 0.0 0.13 11.5 0.0 2.3 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2285 PF10074.9 OAJ26998.1 - 0.064 13.9 4.8 0.19 12.4 2.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) Pilin_PilX PF11530.8 OAJ26998.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Minor type IV pilin, PilX zf-CCHC PF00098.23 OAJ26998.1 - 0.79 9.9 2.6 1.3 9.2 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle AFG1_ATPase PF03969.16 OAJ26999.1 - 8.3e-87 291.4 0.0 2.1e-83 280.2 0.0 3.0 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OAJ26999.1 - 2.9e-05 24.5 0.2 0.00016 22.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ26999.1 - 0.0022 18.3 0.0 0.0097 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ26999.1 - 0.04 14.3 0.0 3.1 8.2 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OAJ26999.1 - 0.11 11.9 0.0 1.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein UvrD-helicase PF00580.21 OAJ26999.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain LIME1 PF15332.6 OAJ26999.1 - 0.45 10.1 2.9 1.5 8.3 0.0 2.7 3 0 0 3 3 3 0 Lck-interacting transmembrane adapter 1 CDC27 PF09507.10 OAJ27000.1 - 3e-29 102.7 69.6 2.6e-17 63.4 0.0 4.5 1 1 1 3 3 3 3 DNA polymerase subunit Cdc27 DEAD PF00270.29 OAJ27001.1 - 2.3e-34 118.7 0.1 5.2e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ27001.1 - 1.6e-28 99.3 0.1 2.9e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAJ27001.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ27001.1 - 0.26 11.5 1.0 2.1 8.6 0.3 2.6 2 1 0 2 2 2 0 AAA domain ThiF PF00899.21 OAJ27002.1 - 1.3e-104 348.9 0.0 7.5e-71 238.3 0.0 2.0 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAJ27002.1 - 1.5e-91 306.8 0.2 2.6e-91 306.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OAJ27002.1 - 2.4e-34 117.4 0.3 5.4e-34 116.2 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OAJ27002.1 - 5.7e-29 100.7 0.0 1.2e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OAJ27002.1 - 3.7e-25 87.9 0.2 8.5e-25 86.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox PF00070.27 OAJ27002.1 - 0.46 11.1 2.3 41 4.8 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GATase PF00117.28 OAJ27003.1 - 2.6e-08 33.9 0.0 2.9e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DUF3433 PF11915.8 OAJ27003.1 - 0.02 15.3 0.3 0.4 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Peptidase_C26 PF07722.13 OAJ27003.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 SUI1 PF01253.22 OAJ27004.1 - 3.6e-20 72.3 0.0 9.5e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAJ27004.1 - 1.5e-10 41.6 0.5 1.4e-07 32.0 0.0 3.0 3 0 0 3 3 3 2 Pre-PUA-like domain AD PF09793.9 OAJ27005.1 - 3e-18 65.7 0.0 5e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain BCDHK_Adom3 PF10436.9 OAJ27007.1 - 5.1e-63 211.7 0.0 7e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ27007.1 - 2.3e-13 50.6 0.0 4.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ27007.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sugar_tr PF00083.24 OAJ27008.1 - 1.2e-19 70.6 17.3 1.3e-15 57.2 7.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ27008.1 - 2.5e-11 43.1 33.7 8.8e-11 41.3 33.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 OAJ27009.1 - 1.7e-43 149.0 2.7 2.2e-43 148.6 2.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAJ27009.1 - 1.4e-16 60.2 0.0 3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAJ27009.1 - 1.1e-12 48.3 7.9 4.7e-11 43.1 0.5 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ27009.1 - 2.9e-07 30.4 0.0 8.6e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 OAJ27009.1 - 0.03 14.9 0.0 0.092 13.3 0.0 1.9 1 0 0 1 1 1 0 Reductase C-terminal K_oxygenase PF13434.6 OAJ27009.1 - 0.091 11.9 0.2 29 3.6 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAJ27009.1 - 0.13 11.6 0.2 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Histone PF00125.24 OAJ27010.1 - 3.6e-44 150.3 3.0 1.7e-43 148.1 3.0 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ27010.1 - 0.0066 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ27010.1 - 0.1 12.9 0.1 0.46 10.8 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAJ27010.1 - 0.11 12.8 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 OAJ27010.1 - 0.15 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mito_carr PF00153.27 OAJ27011.1 - 7.6e-56 186.0 2.6 7.2e-18 64.3 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein SNF2_N PF00176.23 OAJ27012.1 - 2.4e-74 250.1 0.0 5.1e-74 249.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAJ27012.1 - 9.4e-37 125.5 0.2 9.4e-37 125.5 0.2 2.9 5 0 0 5 5 4 1 SLIDE HAND PF09110.11 OAJ27012.1 - 5.5e-32 110.8 4.2 5.5e-32 110.8 4.2 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 OAJ27012.1 - 8.8e-18 64.7 0.0 1.4e-16 60.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ27012.1 - 1.4e-10 41.5 0.0 8.9e-10 38.8 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ27012.1 - 4e-06 26.2 0.0 4e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 OAJ27012.1 - 3.1e-05 24.1 0.0 0.055 13.7 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 OAJ27012.1 - 3.5e-05 23.6 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HWE_HK PF07536.14 OAJ27012.1 - 0.0018 18.9 0.7 0.3 11.8 0.0 3.0 2 0 0 2 2 2 1 HWE histidine kinase AAA_14 PF13173.6 OAJ27012.1 - 0.0068 16.4 0.1 0.024 14.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain DBINO PF13892.6 OAJ27012.1 - 0.0078 16.6 5.8 0.0078 16.6 5.8 3.9 4 0 0 4 4 4 1 DNA-binding domain AAA_22 PF13401.6 OAJ27012.1 - 0.075 13.3 0.1 0.41 10.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Mucin PF01456.17 OAJ27013.1 - 0.096 12.7 15.2 0.18 11.8 15.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S64 PF08192.11 OAJ27013.1 - 1.2 7.5 8.4 1.7 7.0 8.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Zip PF02535.22 OAJ27013.1 - 1.3 8.1 10.6 2.2 7.4 10.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SOG2 PF10428.9 OAJ27013.1 - 2.4 7.3 11.6 3.2 6.8 11.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 OAJ27013.1 - 2.7 6.6 5.6 3.6 6.2 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SIR2 PF02146.17 OAJ27014.1 - 2.6e-26 92.7 0.0 1.1e-19 71.0 0.0 3.7 3 1 0 3 3 3 2 Sir2 family CpXC PF14353.6 OAJ27014.1 - 0.027 14.5 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 CpXC protein zf-CCCH PF00642.24 OAJ27015.1 - 6.7e-08 32.3 26.5 1.1e-05 25.2 2.3 4.7 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med3 PF11593.8 OAJ27015.1 - 1.3 8.2 10.5 2 7.5 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-CCCH_4 PF18044.1 OAJ27015.1 - 2.3 8.1 10.4 0.8 9.6 2.3 3.6 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ27015.1 - 3.1 8.0 24.9 0.76 9.9 4.6 4.5 4 0 0 4 4 4 0 Zinc finger domain Torus PF16131.5 OAJ27015.1 - 3.9 8.2 22.7 0.18 12.5 3.4 3.5 1 1 2 3 3 3 0 Torus domain Chalcone_2 PF16035.5 OAJ27016.1 - 3.2e-37 128.3 0.5 6.6e-36 124.0 0.5 2.5 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 OAJ27016.1 - 6.8e-05 23.0 0.0 0.00047 20.3 0.1 2.0 1 1 1 2 2 2 1 Chalcone isomerase-like Med31 PF05669.12 OAJ27017.1 - 1.5e-28 98.6 0.1 1.8e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 SOH1 eRF1_1 PF03463.15 OAJ27018.1 - 2.1e-49 166.8 0.0 3.1e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 OAJ27018.1 - 3.7e-22 78.9 0.0 7.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 OAJ27018.1 - 3.2e-21 76.0 0.0 4.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 tRNA_anti-codon PF01336.25 OAJ27018.1 - 0.12 12.4 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain PFU PF09070.11 OAJ27019.1 - 3.9e-44 149.5 0.1 7.1e-44 148.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 OAJ27019.1 - 6.4e-43 147.0 1.1 8.8e-43 146.5 1.1 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 OAJ27019.1 - 1.5e-29 101.6 13.7 1.6e-05 25.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ27019.1 - 0.61 10.7 5.3 50 4.6 0.1 4.5 4 1 1 5 5 5 0 PQQ-like domain Chromate_transp PF02417.15 OAJ27020.1 - 3.3e-58 196.3 35.7 3e-34 118.4 11.2 2.4 3 0 0 3 3 3 2 Chromate transporter Sugar_tr PF00083.24 OAJ27021.1 - 2.4e-29 102.5 19.6 2.8e-19 69.3 6.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ27021.1 - 5.3e-14 51.9 43.1 5.3e-09 35.5 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAJ27021.1 - 0.32 9.2 1.2 0.52 8.5 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2207 PF09972.9 OAJ27021.1 - 2.8 6.6 4.4 7.2 5.2 0.0 2.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) FBPase PF00316.20 OAJ27024.1 - 5.6e-74 247.7 0.4 7e-74 247.4 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OAJ27024.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Atx10homo_assoc PF09759.9 OAJ27025.1 - 1.1e-16 60.7 0.0 4.9e-15 55.3 0.0 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neuropeptide_S PF14993.6 OAJ27025.1 - 0.0045 16.8 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Neuropeptide S precursor protein INTS5_C PF14838.6 OAJ27025.1 - 0.012 14.3 0.5 0.018 13.7 0.5 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus BAR PF03114.18 OAJ27026.1 - 1.3e-50 172.3 2.1 1.6e-50 172.0 2.1 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 OAJ27026.1 - 7.1e-05 22.5 1.4 8.7e-05 22.2 1.4 1.1 1 0 0 1 1 1 1 Arfaptin-like domain Ifi-6-16 PF06140.13 OAJ27027.1 - 2.9e-07 30.3 10.2 4.2e-07 29.8 10.2 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family AAA PF00004.29 OAJ27028.1 - 5.5e-31 107.7 0.0 1.2e-30 106.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ27028.1 - 2.1e-07 31.3 0.1 1.2e-06 28.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ27028.1 - 1.1e-06 29.1 0.0 3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OAJ27028.1 - 5.9e-06 26.5 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ27028.1 - 1.8e-05 24.9 0.0 9e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ27028.1 - 2.4e-05 24.9 0.0 5.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OAJ27028.1 - 3.2e-05 24.0 0.1 0.016 15.1 0.1 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OAJ27028.1 - 3.9e-05 23.3 0.1 0.2 11.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain NACHT PF05729.12 OAJ27028.1 - 0.00032 20.6 0.2 0.0029 17.5 0.2 2.2 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 OAJ27028.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ27028.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ27028.1 - 0.0023 17.8 1.5 0.0043 16.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ27028.1 - 0.0027 17.5 0.2 0.011 15.5 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 OAJ27028.1 - 0.0028 17.4 0.1 0.0088 15.8 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAJ27028.1 - 0.0036 17.7 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 OAJ27028.1 - 0.0036 17.3 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAJ27028.1 - 0.0037 17.3 0.1 0.008 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 OAJ27028.1 - 0.0041 16.6 0.0 0.48 9.8 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein Cytidylate_kin PF02224.18 OAJ27028.1 - 0.0045 16.7 0.1 0.0087 15.8 0.1 1.6 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 OAJ27028.1 - 0.005 17.1 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ27028.1 - 0.0053 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 OAJ27028.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 OAJ27028.1 - 0.0089 15.2 0.0 0.047 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OAJ27028.1 - 0.018 14.3 0.0 1.1 8.5 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.13 OAJ27028.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 OAJ27028.1 - 0.024 14.5 0.1 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAJ27028.1 - 0.031 13.7 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OAJ27028.1 - 0.037 14.5 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 OAJ27028.1 - 0.038 14.3 0.0 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ27028.1 - 0.045 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 OAJ27028.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAJ27028.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 OAJ27028.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 OAJ27028.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SPC25 PF06703.11 OAJ27028.1 - 0.097 12.5 0.1 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CPT PF07931.12 OAJ27028.1 - 0.098 12.5 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 OAJ27028.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OAJ27028.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RdRP PF05183.12 OAJ27029.1 - 4.2e-166 554.0 0.0 6e-166 553.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RNase_T PF00929.24 OAJ27030.1 - 7.2e-10 39.7 0.0 8.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF4363 PF14276.6 OAJ27030.1 - 0.089 12.9 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) RNase_T PF00929.24 OAJ27031.1 - 2.6e-10 41.1 0.1 3.1e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Exonuclease Telomere_reg-2 PF10193.9 OAJ27032.1 - 5.6e-27 94.3 0.0 2.5e-26 92.2 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein MCM PF00493.23 OAJ27033.1 - 4.7e-105 349.7 0.0 7.2e-105 349.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ27033.1 - 6.6e-34 116.5 0.0 1.2e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ27033.1 - 9.1e-29 99.7 0.8 2.3e-28 98.5 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ27033.1 - 1.1e-13 51.7 0.0 2.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ27033.1 - 1.8e-06 27.5 0.0 0.00045 19.7 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ27033.1 - 6.4e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAJ27033.1 - 0.00012 21.9 0.0 0.0017 18.2 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ27033.1 - 0.031 14.0 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 OAJ27033.1 - 0.11 13.1 1.0 0.32 11.7 0.4 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 OAJ27033.1 - 0.11 12.9 0.1 0.64 10.4 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L28e PF01778.17 OAJ27034.1 - 1.6e-23 83.7 0.3 2.6e-23 82.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Citrate_ly_lig PF08218.11 OAJ27034.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain Sec1 PF00995.23 OAJ27035.1 - 7.9e-87 292.8 0.0 1.4e-86 292.0 0.0 1.4 1 0 0 1 1 1 1 Sec1 family CBFD_NFYB_HMF PF00808.23 OAJ27036.1 - 6.7e-21 74.3 0.1 1.2e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ27036.1 - 0.0024 18.2 4.3 0.0032 17.8 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ27036.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Prefoldin PF02996.17 OAJ27037.1 - 3.3e-30 104.5 0.0 4.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit NBP1 PF08537.10 OAJ27037.1 - 0.019 14.4 1.9 0.028 13.8 1.9 1.3 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 Cortex-I_coil PF09304.10 OAJ27037.1 - 0.037 14.3 3.4 0.3 11.3 0.3 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil NADH_4Fe-4S PF10589.9 OAJ27037.1 - 0.082 13.0 0.4 9 6.4 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Rx_N PF18052.1 OAJ27037.1 - 0.17 12.2 3.8 3.5 8.0 0.7 2.5 1 1 1 2 2 2 0 Rx N-terminal domain Bestrophin PF01062.21 OAJ27038.1 - 3.9e-33 115.1 0.1 6.6e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MCLC PF05934.11 OAJ27040.1 - 0.15 10.8 0.9 0.35 9.6 0.9 1.5 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF572 PF04502.13 OAJ27040.1 - 2.8 7.5 8.1 1.3 8.6 4.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) UCH PF00443.29 OAJ27041.1 - 3.6e-64 216.7 0.0 5.7e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ27041.1 - 1e-20 74.6 0.0 2.8e-17 63.3 0.0 2.8 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 OAJ27041.1 - 2.5e-07 30.9 1.1 6.7e-07 29.5 1.1 1.7 1 1 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 OAJ27041.1 - 0.0084 16.6 0.0 0.057 13.9 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain DUF104 PF01954.16 OAJ27041.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 zf-MIZ PF02891.20 OAJ27041.1 - 0.28 10.9 0.7 0.54 10.1 0.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Paramyxo_P_V_N PF13825.6 OAJ27041.1 - 0.82 9.0 7.3 2.4 7.5 0.6 2.3 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus Fibrillarin PF01269.17 OAJ27042.1 - 1.9e-104 347.7 0.0 2.4e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAJ27042.1 - 2.5e-05 24.1 0.1 3.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 OAJ27042.1 - 0.0029 17.7 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OAJ27042.1 - 0.0034 17.0 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OAJ27042.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shadoo PF14999.6 OAJ27042.1 - 3.7 7.7 14.0 1.2 9.2 11.3 1.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RRM_1 PF00076.22 OAJ27043.1 - 1.8e-17 62.9 0.0 2.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ27043.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ27043.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 RL domain DUF2407_C PF13373.6 OAJ27044.1 - 4.4e-12 46.4 3.1 8.1e-12 45.5 0.9 2.4 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAJ27044.1 - 1.2e-11 45.1 0.7 3e-10 40.6 0.2 2.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAJ27044.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1769 PF08588.10 OAJ27045.1 - 2e-15 56.7 0.2 3.6e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) FeS_assembly_P PF01883.19 OAJ27046.1 - 1e-11 44.8 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 OAJ27047.1 - 1e-25 90.3 0.0 1.8e-25 89.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ27047.1 - 1e-09 38.3 6.5 1.9e-09 37.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box_5 PF18511.1 OAJ27051.1 - 0.17 11.4 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 F-box DUF1708 PF08101.11 OAJ27052.1 - 2.9e-15 56.4 0.1 2.3e-10 40.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 OAJ27052.1 - 0.012 15.4 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 RhoGAP domain CDC45 PF02724.14 OAJ27053.1 - 6.9e-203 675.5 0.0 1.9e-202 674.0 0.0 1.6 1 1 0 1 1 1 1 CDC45-like protein Cas_Csy4 PF09618.10 OAJ27053.1 - 0.04 14.1 0.1 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) DUF4604 PF15377.6 OAJ27053.1 - 1.3 9.5 34.2 1 9.7 24.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) BUD22 PF09073.10 OAJ27053.1 - 1.5 8.1 42.7 3.3 7.0 35.1 2.1 2 0 0 2 2 2 0 BUD22 FAD_binding_7 PF03441.14 OAJ27068.1 - 3.8e-73 245.3 0.6 6.2e-73 244.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ27068.1 - 1.2e-39 136.0 0.0 1.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase p450 PF00067.22 OAJ27069.1 - 1.4e-67 228.4 0.0 4.8e-53 180.5 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 DUF2085 PF09858.9 OAJ27069.1 - 0.22 12.0 1.1 6.7 7.3 0.0 3.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2085) Ribosomal_L13 PF00572.18 OAJ27070.1 - 2e-10 41.0 0.5 1.5e-08 34.9 0.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 TMEM189_B_dmain PF10520.9 OAJ27070.1 - 0.15 12.2 0.2 0.22 11.7 0.2 1.2 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain Ribosomal_L32e PF01655.18 OAJ27071.1 - 1.5e-46 157.2 1.0 1.8e-46 157.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF1771 PF08590.10 OAJ27072.1 - 9e-21 74.0 9.3 2.4e-20 72.7 9.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAJ27072.1 - 3.2e-13 49.8 1.1 6.2e-13 48.9 0.4 1.9 2 0 0 2 2 2 1 Smr domain Spt20 PF12090.8 OAJ27072.1 - 3 7.4 7.6 4.4 6.9 7.6 1.4 1 0 0 1 1 1 0 Spt20 family RNB PF00773.19 OAJ27076.1 - 2.4e-50 171.7 0.0 4.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain DUF1708 PF08101.11 OAJ27077.1 - 8.9e-25 87.7 0.2 3.4e-18 66.0 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 OAJ27077.1 - 0.00027 20.8 0.0 0.0008 19.3 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain HAMP_N3 PF18575.1 OAJ27077.1 - 0.037 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 DNA_pol_phi PF04931.13 OAJ27077.1 - 7.6 4.5 4.9 13 3.7 4.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Zn_clus PF00172.18 OAJ27078.1 - 0.00018 21.5 11.4 0.00031 20.8 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4179 PF13786.6 OAJ27078.1 - 0.0091 16.4 0.1 24 5.5 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4179) DUF3464 PF11947.8 OAJ27078.1 - 0.58 9.9 9.6 0.18 11.5 3.3 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Zip PF02535.22 OAJ27078.1 - 3.9 6.6 18.9 0.85 8.8 6.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OAJ27078.1 - 8.6 6.3 10.9 10 6.1 4.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Dus PF01207.17 OAJ27079.1 - 2.2e-44 151.8 0.0 8.7e-25 87.4 0.0 3.0 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) Mito_carr PF00153.27 OAJ27080.1 - 6.6e-71 234.3 0.9 1.4e-24 85.8 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIE-A_C PF11521.8 OAJ27080.1 - 0.21 11.9 1.2 0.42 11.0 1.2 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha PGA2 PF07543.12 OAJ27080.1 - 1.3 9.0 3.0 1.2 9.2 1.6 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L14 PF00238.19 OAJ27081.1 - 4.1e-43 146.3 1.1 4.7e-43 146.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 OAJ27082.1 - 1.2e-65 221.5 0.1 6e-60 202.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27082.1 - 3.4e-36 124.8 0.1 2.5e-33 115.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 OAJ27082.1 - 4.1e-17 61.7 0.4 6.9e-17 61.0 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 OAJ27082.1 - 6.1e-05 22.5 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ27082.1 - 0.00018 21.5 0.8 0.0053 16.7 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ27082.1 - 0.0012 17.9 0.1 0.0019 17.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ27082.1 - 0.0052 16.1 0.0 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like SET PF00856.28 OAJ27083.1 - 1e-09 39.0 0.0 1e-09 39.0 0.0 3.2 3 1 0 3 3 3 1 SET domain Cytochrom_NNT PF03264.14 OAJ27083.1 - 0.038 13.7 1.2 0.086 12.5 1.2 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DNA_pol_phi PF04931.13 OAJ27083.1 - 6.4 4.8 17.2 10 4.0 17.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 OAJ27084.1 - 1.8e-62 211.1 0.0 2.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27084.1 - 5e-33 114.5 0.0 6.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ27084.1 - 1.6e-07 30.4 0.0 2.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ27084.1 - 0.0001 21.7 0.0 0.00025 20.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ27084.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ27084.1 - 0.042 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ27084.1 - 0.093 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 OAJ27084.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SNRNP27 PF08648.12 OAJ27085.1 - 4.2e-26 90.8 1.7 7.4e-26 90.0 0.4 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins LapA_dom PF06305.11 OAJ27087.1 - 0.079 12.8 0.3 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MARVEL PF01284.23 OAJ27088.1 - 8.2e-06 25.9 9.8 1.4e-05 25.2 9.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.22 OAJ27088.1 - 0.0011 18.3 0.5 0.0016 17.8 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SLATT_4 PF18186.1 OAJ27088.1 - 0.11 12.2 0.6 0.22 11.1 0.6 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 MgtE PF01769.16 OAJ27088.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.2 2 1 0 2 2 2 0 Divalent cation transporter EI24 PF07264.11 OAJ27088.1 - 2.5 8.3 12.5 0.22 11.8 6.2 1.9 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) HEAT PF02985.22 OAJ27090.1 - 6.3e-35 116.2 20.2 0.01 16.0 0.0 13.8 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 OAJ27090.1 - 1.1e-32 112.2 10.5 1.4e-11 44.6 0.0 6.9 3 3 4 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 OAJ27090.1 - 2.2e-10 40.8 16.3 0.84 10.2 0.1 8.2 7 1 1 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ27090.1 - 4.5e-10 40.0 0.9 0.063 13.9 0.1 6.6 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ27090.1 - 2.4e-07 31.0 9.2 0.016 15.3 0.1 5.2 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ27090.1 - 0.00038 19.1 4.9 0.049 12.2 0.2 4.1 4 1 0 5 5 5 1 Adaptin N terminal region CLASP_N PF12348.8 OAJ27090.1 - 0.00075 19.1 0.9 0.019 14.5 0.1 3.6 1 1 2 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 OAJ27090.1 - 0.029 14.5 3.9 9.5 6.4 0.1 3.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 API5 PF05918.11 OAJ27090.1 - 0.041 12.7 0.5 0.17 10.7 0.0 2.3 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) M11L PF11099.8 OAJ27090.1 - 0.1 12.8 0.3 8.1 6.7 0.1 2.9 2 1 0 2 2 2 0 Apoptosis regulator M11L like DNA_pol_B PF00136.21 OAJ27091.1 - 2.8e-99 332.9 0.0 3.5e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAJ27091.1 - 4.8e-23 81.8 0.0 2.3e-13 50.0 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAJ27091.1 - 1e-11 45.1 6.2 1.9e-11 44.2 6.2 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Aldedh PF00171.22 OAJ27093.1 - 2.9e-129 431.6 0.0 3.4e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family S-methyl_trans PF02574.16 OAJ27094.1 - 5.2e-51 174.0 0.0 6.3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DnaJ PF00226.31 OAJ27095.1 - 1.2e-19 70.1 0.5 2.3e-19 69.3 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 OAJ27095.1 - 0.00031 20.8 3.1 0.00063 19.8 3.1 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 OAJ27095.1 - 0.074 13.1 6.7 0.19 11.8 6.7 1.6 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.6 OAJ27095.1 - 0.67 9.8 9.1 2.7 7.9 9.1 2.0 1 1 0 1 1 1 0 Glycine-zipper domain Vps39_1 PF10366.9 OAJ27096.1 - 3.4e-28 98.1 0.8 1e-27 96.5 0.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OAJ27096.1 - 5.7e-19 68.6 0.7 1.3e-18 67.4 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAJ27096.1 - 1.3e-13 51.2 0.0 2.9e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.20 OAJ27096.1 - 3.1e-08 33.6 5.3 4.1e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_19 PF14559.6 OAJ27096.1 - 0.2 12.2 6.4 0.63 10.6 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ27096.1 - 0.46 10.4 4.2 2.2 8.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 OAJ27097.1 - 0.055 13.5 5.8 0.082 12.9 5.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glypican PF01153.19 OAJ27097.1 - 0.51 9.1 0.9 0.66 8.7 0.9 1.1 1 0 0 1 1 1 0 Glypican Sporozoite_P67 PF05642.11 OAJ27097.1 - 3.5 5.6 12.1 4.9 5.1 12.1 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen EamA PF00892.20 OAJ27098.1 - 1.5e-07 31.7 20.6 0.00021 21.5 6.4 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF1003 PF06210.11 OAJ27098.1 - 0.00066 19.7 0.3 0.0027 17.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) DUF3955 PF13127.6 OAJ27098.1 - 0.0027 17.5 2.5 0.0027 17.5 2.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) SUIM_assoc PF16619.5 OAJ27098.1 - 0.02 15.0 1.1 0.64 10.1 0.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-CCHC PF00098.23 OAJ27099.1 - 3.4e-12 45.8 16.9 0.00053 19.9 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ27099.1 - 0.00017 21.2 16.6 0.064 13.0 0.3 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ27099.1 - 0.00049 19.8 15.5 0.085 12.7 0.0 4.3 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ27099.1 - 0.22 11.4 0.1 0.22 11.4 0.1 4.7 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ27099.1 - 5.2 6.9 14.6 15 5.4 0.2 4.4 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger EPSP_synthase PF00275.20 OAJ27100.1 - 4.6e-108 361.6 0.0 6.6e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAJ27100.1 - 1.4e-96 322.7 0.0 4.4e-96 321.1 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAJ27100.1 - 6.6e-39 134.5 0.0 1.3e-38 133.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAJ27100.1 - 5.8e-23 80.9 0.0 2.3e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAJ27100.1 - 7.7e-21 74.9 0.0 5.9e-19 68.7 0.0 3.1 2 1 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 OAJ27100.1 - 4.9e-11 42.2 0.1 2.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAJ27100.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 OAJ27100.1 - 0.00033 20.5 0.4 0.00087 19.1 0.4 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 OAJ27100.1 - 0.044 12.6 0.9 0.16 10.7 0.9 1.9 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Asparaginase_C PF17763.1 OAJ27100.1 - 0.1 12.8 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain DUF1295 PF06966.12 OAJ27101.1 - 7.6e-41 140.2 0.8 1.4e-40 139.3 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAJ27101.1 - 0.0004 20.4 1.7 0.00088 19.3 0.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAJ27101.1 - 0.014 15.8 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ27101.1 - 0.034 14.5 2.2 0.055 13.9 0.0 2.4 3 0 0 3 3 3 0 Phospholipid methyltransferase His_Phos_2 PF00328.22 OAJ27102.1 - 4.5e-27 95.4 0.0 1.7e-26 93.4 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_C13 PF01650.18 OAJ27104.1 - 3.2e-43 148.1 0.4 4.5e-43 147.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase C13 family MMM1 PF10296.9 OAJ27106.1 - 5.8e-68 229.4 0.0 4.2e-47 160.8 0.0 2.6 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 adh_short_C2 PF13561.6 OAJ27107.1 - 4.1e-42 144.3 0.1 5.7e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ27107.1 - 9.5e-41 139.4 0.1 1.9e-40 138.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ27107.1 - 5.7e-08 32.9 0.1 9.7e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 KR domain PsiA PF06952.11 OAJ27108.1 - 0.044 13.0 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Cas_DxTHG PF09455.10 OAJ27108.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Vps55 PF04133.14 OAJ27109.1 - 3.3e-42 143.1 7.7 3.7e-42 143.0 7.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 zf-RING_4 PF14570.6 OAJ27110.1 - 1.8e-21 75.7 11.6 2.8e-21 75.0 11.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OAJ27110.1 - 1.6e-06 27.9 8.9 2.7e-06 27.2 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ27110.1 - 0.0001 22.1 9.0 0.0069 16.2 9.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Spt20 PF12090.8 OAJ27110.1 - 0.0061 16.2 11.9 0.0061 16.2 11.9 7.2 5 1 0 5 5 5 1 Spt20 family zf-RING_2 PF13639.6 OAJ27110.1 - 0.0064 16.8 11.8 0.011 16.0 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain TFIIA PF03153.13 OAJ27110.1 - 0.016 15.2 0.0 0.016 15.2 0.0 7.0 3 2 3 7 7 7 0 Transcription factor IIA, alpha/beta subunit zf-UDP PF14569.6 OAJ27110.1 - 0.041 14.0 4.0 0.091 12.9 4.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_1 PF00076.22 OAJ27110.1 - 0.048 13.5 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 OAJ27110.1 - 1.3 9.0 11.5 2.3 8.2 11.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 OAJ27110.1 - 1.4 8.8 7.8 1.1 9.2 6.2 1.7 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) His_Phos_1 PF00300.22 OAJ27111.1 - 1.4e-08 34.7 0.0 3.8e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OAJ27111.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DEC-1_N PF04625.13 OAJ27111.1 - 4.1 6.3 10.5 5.9 5.8 10.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2828 PF11443.8 OAJ27112.1 - 8.8e-204 678.2 0.0 1.1e-203 677.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Asp PF00026.23 OAJ27113.1 - 1.5e-28 100.2 0.0 4.7e-28 98.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ27113.1 - 0.0015 18.8 1.3 0.024 14.9 1.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ27113.1 - 0.051 14.2 0.0 5.6 7.7 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease Ras PF00071.22 OAJ27114.1 - 3.8e-58 195.6 0.0 4.4e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ27114.1 - 8.9e-23 80.8 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ27114.1 - 1.2e-06 28.1 0.0 2.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ27114.1 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ27114.1 - 0.0045 16.4 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ27114.1 - 0.075 12.4 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AMP-binding PF00501.28 OAJ27115.1 - 1.5e-32 112.7 0.1 3.9e-32 111.4 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ27115.1 - 5.8e-25 87.9 0.0 9.6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ27115.1 - 1.8e-08 34.2 0.0 4.9e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAJ27115.1 - 5.4e-06 26.7 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ27115.1 - 0.059 14.3 0.3 2.5 9.1 0.1 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 OAJ27115.1 - 0.19 10.8 0.0 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Oxidored_molyb PF00174.19 OAJ27122.1 - 1.1e-51 174.9 0.0 1.9e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAJ27122.1 - 6.1e-43 146.1 0.1 1.3e-42 145.1 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 OAJ27122.1 - 6.1e-25 87.5 0.0 1.3e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ27122.1 - 4.1e-22 78.9 0.0 3.3e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAJ27122.1 - 1.4e-18 66.8 0.0 2.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAJ27122.1 - 0.00044 20.4 0.0 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain MFS_1 PF07690.16 OAJ27123.1 - 4.5e-27 94.9 29.9 8.7e-27 94.0 29.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.21 OAJ27124.1 - 2.4e-62 210.3 0.0 6.7e-62 208.9 0.0 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ27124.1 - 3.8e-32 112.1 8.6 1.7e-31 110.0 8.6 2.1 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ27124.1 - 6.5e-19 68.2 0.0 1.5e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAJ27124.1 - 1.8e-08 34.7 1.2 6.2e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 MutS domain II AAA_27 PF13514.6 OAJ27124.1 - 0.00071 19.2 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAJ27124.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HHV-1_VABD PF16852.5 OAJ27124.1 - 0.18 11.8 1.5 1.7 8.7 0.2 2.9 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain AAA_23 PF13476.6 OAJ27124.1 - 1.5 9.3 0.0 1.5 9.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF2052 PF09747.9 OAJ27124.1 - 4.9 7.2 5.5 0.98 9.5 1.6 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Oxysterol_BP PF01237.18 OAJ27125.1 - 3.4e-85 286.1 1.6 4.7e-83 279.1 1.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ras PF00071.22 OAJ27126.1 - 1.7e-50 170.8 0.1 2e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ27126.1 - 1.3e-30 106.1 0.0 2.1e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ27126.1 - 1.6e-11 44.0 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ27126.1 - 0.00031 20.2 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ27126.1 - 0.00038 19.7 0.1 0.083 12.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OAJ27126.1 - 0.0055 16.8 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAJ27126.1 - 0.021 15.2 0.3 0.74 10.2 0.3 2.2 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OAJ27126.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 OAJ27126.1 - 0.066 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 OAJ27126.1 - 0.089 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAJ27126.1 - 0.11 12.5 0.2 13 5.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 OAJ27126.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 OAJ27126.1 - 0.12 11.6 0.2 0.19 11.0 0.1 1.5 2 0 0 2 2 2 0 Septin TsaE PF02367.17 OAJ27126.1 - 0.13 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thioredoxin PF00085.20 OAJ27127.1 - 1.7e-21 76.2 0.0 2.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ27127.1 - 2e-06 28.2 0.0 6.5e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAJ27127.1 - 8.4e-05 22.5 0.0 9.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OAJ27127.1 - 0.00025 21.3 0.0 0.013 15.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like KaiB PF07689.12 OAJ27127.1 - 0.00066 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin_3 PF13192.6 OAJ27127.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 OAJ27127.1 - 0.0028 17.8 0.1 0.0056 16.8 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 OAJ27127.1 - 0.0059 16.5 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 OAJ27127.1 - 0.0061 16.3 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF836 PF05768.14 OAJ27127.1 - 0.0064 16.9 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 OAJ27127.1 - 0.0088 15.7 0.1 0.036 13.7 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 OAJ27127.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 OAJ27127.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 OAJ27127.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 OAJ27127.1 - 0.03 14.1 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin OrsD PF12013.8 OAJ27128.1 - 8e-06 26.3 1.3 0.00085 19.8 0.1 2.4 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D Nic96 PF04097.14 OAJ27129.1 - 2.9e-169 564.4 0.0 4.1e-169 564.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Voltage_CLC PF00654.20 OAJ27130.1 - 7.6e-91 305.0 29.9 1.5e-90 304.1 29.9 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 OAJ27130.1 - 8.7e-12 45.3 0.0 5.6e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain EMP24_GP25L PF01105.24 OAJ27131.1 - 2.8e-50 170.8 0.0 3.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OAJ27131.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain Pyr_redox_2 PF07992.14 OAJ27132.1 - 1.4e-43 149.3 0.7 2.4e-41 141.9 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAJ27132.1 - 1.7e-18 66.6 0.0 3.3e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAJ27132.1 - 9.4e-17 61.4 6.4 2e-13 50.7 0.7 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ27132.1 - 1.1e-15 57.4 0.0 3.1e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 OAJ27132.1 - 4.4e-15 55.8 5.5 1.7e-10 41.1 6.1 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 OAJ27132.1 - 7.1e-13 48.2 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 OAJ27132.1 - 2.8e-11 43.2 0.1 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 OAJ27132.1 - 1.7e-05 24.7 0.2 0.045 13.7 0.0 2.9 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 OAJ27132.1 - 2e-05 24.0 0.1 11 5.2 0.0 4.1 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ27132.1 - 0.00042 20.0 0.9 0.34 10.4 0.1 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ27132.1 - 0.00047 19.3 4.5 0.097 11.7 0.2 3.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 OAJ27132.1 - 0.0022 18.0 4.2 2.7 8.0 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ27132.1 - 0.013 15.8 2.0 1.6 9.0 0.3 2.8 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 OAJ27132.1 - 0.015 14.5 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OAJ27132.1 - 0.021 15.3 1.3 4.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OAJ27132.1 - 0.17 12.2 0.2 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAJ27132.1 - 0.2 11.9 0.7 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PAC2 PF09754.9 OAJ27133.1 - 3.9e-25 89.1 0.0 5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Aminotran_1_2 PF00155.21 OAJ27134.1 - 3.7e-33 115.2 0.0 4.4e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II bZIP_1 PF00170.21 OAJ27135.1 - 0.00012 22.1 10.3 0.00028 20.9 9.6 2.0 1 1 1 2 2 2 1 bZIP transcription factor RskA PF10099.9 OAJ27135.1 - 0.0032 17.8 11.2 0.0032 17.8 11.2 3.3 2 2 1 3 3 2 1 Anti-sigma-K factor rskA FHIPEP PF00771.20 OAJ27135.1 - 0.21 10.0 3.4 0.34 9.3 3.4 1.3 1 0 0 1 1 1 0 FHIPEP family CD20 PF04103.15 OAJ27135.1 - 0.24 11.5 0.6 0.39 10.8 0.6 1.2 1 0 0 1 1 1 0 CD20-like family Otopetrin PF03189.13 OAJ27135.1 - 0.25 10.1 0.2 0.28 10.0 0.2 1.2 1 0 0 1 1 1 0 Otopetrin SpoIIP PF07454.11 OAJ27135.1 - 0.39 10.1 10.5 1.8 7.9 8.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) P5-ATPase PF12409.8 OAJ27135.1 - 2 8.6 3.4 4 7.6 3.4 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter FAM76 PF16046.5 OAJ27135.1 - 4.1 6.7 14.5 1.1 8.6 7.9 2.1 2 0 0 2 2 2 0 FAM76 protein GREB1 PF15782.5 OAJ27135.1 - 4.2 4.4 11.3 7.4 3.5 11.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EPL1 PF10513.9 OAJ27135.1 - 7.1 7.0 13.9 0.55 10.6 7.3 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like BAF1_ABF1 PF04684.13 OAJ27135.1 - 8.4 5.3 21.2 0.036 13.1 9.8 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.14 OAJ27135.1 - 9.6 5.5 24.3 18 4.6 24.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_L5_C PF00673.21 OAJ27136.1 - 1.7e-15 56.9 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAJ27136.1 - 0.047 14.0 0.3 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L5 PhoD PF09423.10 OAJ27138.1 - 1.2e-36 126.5 0.1 2.3e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase Cyclin PF08613.11 OAJ27140.1 - 3.8e-10 40.4 0.0 8.2e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAJ27140.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sel_put PF04328.13 OAJ27140.1 - 0.2 11.7 8.1 0.054 13.5 3.5 2.6 2 0 0 2 2 2 0 Selenoprotein, putative Hydantoinase_B PF02538.14 OAJ27141.1 - 0.077 11.4 1.7 0.1 11.0 1.7 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase ALMT PF11744.8 OAJ27141.1 - 3.1 6.5 16.2 4 6.2 16.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 OAJ27141.1 - 8.5 5.5 5.4 11 5.1 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter 14-3-3 PF00244.20 OAJ27142.1 - 1.7e-108 361.3 4.1 1.9e-108 361.1 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 OAJ27142.1 - 0.35 11.4 2.6 0.62 10.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HisKA PF00512.25 OAJ27142.1 - 0.74 9.9 2.7 1.5 8.9 0.2 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Adaptin_N PF01602.20 OAJ27143.1 - 8.4e-126 420.6 8.6 1e-125 420.3 8.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAJ27143.1 - 7.5e-41 138.9 0.0 2.7e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAJ27143.1 - 2.6e-16 59.9 0.0 7.9e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 OAJ27143.1 - 0.29 11.5 1.4 8 6.9 0.1 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 OAJ27143.1 - 3.9 8.0 7.6 1.3 9.4 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat SAGA-Tad1 PF12767.7 OAJ27144.1 - 1.3e-44 152.7 0.0 4.8e-44 150.9 0.0 1.9 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TrbI PF03743.14 OAJ27144.1 - 0.037 13.8 3.3 3.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein EccE PF11203.8 OAJ27144.1 - 3.2 8.2 9.4 2.1 8.7 3.2 3.0 1 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PsbW PF07123.12 OAJ27144.1 - 8.5 6.4 7.8 0.85 9.6 0.1 2.8 3 1 1 4 4 4 0 Photosystem II reaction centre W protein (PsbW) ANAPC4_WD40 PF12894.7 OAJ27145.1 - 9.4e-06 25.8 0.0 0.083 13.2 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ27145.1 - 0.0005 20.8 3.3 0.094 13.6 0.3 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.9 OAJ27145.1 - 0.057 13.4 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) zf-HC5HC2H_2 PF13832.6 OAJ27146.1 - 1.5e-19 70.1 1.8 1.5e-19 70.1 1.8 4.6 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAJ27146.1 - 7.7e-16 58.1 1.7 7.7e-16 58.1 1.7 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 OAJ27146.1 - 2.9e-14 52.7 47.0 2.6e-09 36.8 5.9 5.3 6 0 0 6 6 6 3 PHD-finger BAH PF01426.18 OAJ27146.1 - 1.7e-09 37.6 0.0 4.7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 BAH domain GATA PF00320.27 OAJ27146.1 - 1.9e-06 27.4 3.3 1.9e-06 27.4 3.3 4.2 4 0 0 4 4 4 1 GATA zinc finger PHD_2 PF13831.6 OAJ27146.1 - 0.00015 21.3 3.0 0.00015 21.3 3.0 5.7 6 0 0 6 6 6 2 PHD-finger Myb_DNA-bind_7 PF15963.5 OAJ27146.1 - 0.0036 17.1 0.3 0.011 15.6 0.3 1.8 1 0 0 1 1 1 1 Myb DNA-binding like ELM2 PF01448.24 OAJ27146.1 - 0.011 16.4 0.1 0.16 12.7 0.0 2.9 3 0 0 3 3 3 0 ELM2 domain TMP_2 PF06791.13 OAJ27146.1 - 3.7 7.2 8.7 1.7 8.3 1.1 2.4 2 0 0 2 2 2 0 Prophage tail length tape measure protein C1_1 PF00130.22 OAJ27146.1 - 8.7 6.3 31.8 0.21 11.5 1.4 4.7 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF498 PF04430.14 OAJ27147.1 - 1.1e-25 89.8 0.0 2e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.13 OAJ27148.1 - 1.4e-06 28.3 5.5 2e-06 27.8 5.5 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAJ27148.1 - 0.0073 16.3 2.5 0.011 15.8 2.5 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OAJ27148.1 - 0.036 14.4 5.1 0.3 11.4 5.0 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 OAJ27148.1 - 0.12 12.7 4.7 0.81 10.1 0.7 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.17 OAJ27148.1 - 0.13 12.5 1.0 0.19 12.0 1.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 OAJ27148.1 - 0.25 11.6 2.5 1.8 8.9 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 OAJ27148.1 - 0.37 10.8 5.1 1.1 9.3 5.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like ZapB PF06005.12 OAJ27149.1 - 0.16 12.4 1.5 0.3 11.5 0.0 2.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF1770 PF08589.10 OAJ27149.1 - 0.25 12.3 1.5 0.81 10.7 1.5 1.9 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Transposase_21 PF02992.14 OAJ27150.1 - 5.7e-05 22.5 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4893 PF16233.5 OAJ27150.1 - 0.0026 17.4 0.0 2.7 7.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4893) DUF1186 PF06685.11 OAJ27150.1 - 0.097 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) bZIP_1 PF00170.21 OAJ27152.1 - 0.00013 22.0 9.9 0.00013 22.0 9.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ27152.1 - 0.0035 17.4 9.0 0.0035 17.4 9.0 2.0 2 0 0 2 2 2 1 Basic region leucine zipper RasGAP PF00616.19 OAJ27153.1 - 2.4e-20 73.1 0.0 1.6e-12 47.5 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 OAJ27153.1 - 1.7e-09 38.0 0.0 5.8e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 OAJ27153.1 - 0.00011 22.2 0.1 0.0009 19.2 0.0 2.6 2 0 0 2 2 2 1 Cell morphogenesis C-terminal NMO PF03060.15 OAJ27156.1 - 1.1e-32 113.7 3.2 2.1e-19 70.1 0.4 3.8 2 2 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAJ27156.1 - 0.0022 17.1 0.5 0.0047 16.0 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAJ27156.1 - 0.14 11.1 0.0 0.53 9.2 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TFIIE-A_C PF11521.8 OAJ27156.1 - 0.44 10.9 5.0 1.8 8.9 0.8 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Clat_adaptor_s PF01217.20 OAJ27157.1 - 7.3e-09 35.7 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4266 PF14086.6 OAJ27157.1 - 0.0085 17.0 3.8 0.68 10.9 0.4 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4266) DUF4337 PF14235.6 OAJ27157.1 - 0.16 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RRM_1 PF00076.22 OAJ27158.1 - 6.9e-73 240.4 0.0 2.5e-18 65.6 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ27158.1 - 2.3e-06 27.2 0.0 0.42 10.2 0.0 5.3 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ27158.1 - 6.2e-06 26.0 0.0 0.43 10.5 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 OAJ27158.1 - 0.0001 22.4 0.0 0.19 11.9 0.0 3.9 5 0 0 5 5 5 1 RNA recognition motif RRM_Rrp7 PF17799.1 OAJ27158.1 - 0.00028 20.7 0.7 26 4.6 0.0 5.4 4 2 2 6 6 6 0 Rrp7 RRM-like N-terminal domain RRM_2 PF04059.12 OAJ27158.1 - 0.0064 16.7 0.0 7.6 6.8 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif 2 PHM7_cyt PF14703.6 OAJ27158.1 - 0.015 15.6 1.1 15 5.8 0.0 5.1 5 3 2 7 7 7 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 OAJ27158.1 - 0.021 14.9 2.8 0.46 10.6 0.0 4.3 4 2 1 5 5 4 0 Limkain b1 SET_assoc PF11767.8 OAJ27158.1 - 0.026 14.2 0.0 29 4.4 0.0 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 OAJ27158.1 - 0.029 14.4 0.0 8.1 6.5 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1980 PF09323.10 OAJ27158.1 - 1.2 9.0 3.0 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) YtxH PF12732.7 OAJ27158.1 - 3.4 8.3 7.9 15 6.2 7.9 2.1 1 0 0 1 1 1 0 YtxH-like protein LIM PF00412.22 OAJ27159.1 - 2.5e-19 69.2 18.1 4.6e-11 42.8 6.6 3.0 2 1 0 2 2 2 2 LIM domain zf-CSL PF05207.13 OAJ27159.1 - 2.6 7.8 7.5 4.7 7.0 0.9 2.5 2 0 0 2 2 2 0 CSL zinc finger RhoGAP PF00620.27 OAJ27160.1 - 2e-43 147.8 0.0 3.5e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OAJ27160.1 - 1.4e-05 25.5 0.0 0.00014 22.4 0.0 2.4 1 1 0 1 1 1 1 PH domain PX PF00787.24 OAJ27160.1 - 3.9e-05 23.6 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PX domain RabGAP-TBC PF00566.18 OAJ27161.1 - 1.5e-48 165.3 0.0 2.3e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 OAJ27161.1 - 1.8e-06 27.8 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain NUDIX PF00293.28 OAJ27162.1 - 4.9e-07 29.8 0.0 9.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain eIF-5a PF01287.20 OAJ27163.1 - 1.5e-29 101.9 1.3 2e-29 101.5 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PCMD PF13201.6 OAJ27163.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Putative carbohydrate metabolism domain EFP_N PF08207.12 OAJ27163.1 - 0.028 14.4 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Pil1 PF13805.6 OAJ27163.1 - 0.098 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 ABC2_membrane PF01061.24 OAJ27164.1 - 3.8e-63 212.7 52.6 2.5e-32 112.0 20.1 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ27164.1 - 9.5e-37 126.6 0.0 1.3e-18 67.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAJ27164.1 - 7.9e-20 70.6 0.0 7.9e-20 70.6 0.0 3.8 4 0 0 4 4 4 1 CDR ABC transporter ABC_trans_N PF14510.6 OAJ27164.1 - 9e-10 39.0 0.3 2.9e-09 37.4 0.3 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAJ27164.1 - 2.4e-07 31.3 3.4 0.0027 18.1 0.6 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 OAJ27164.1 - 2.3e-05 24.1 0.4 0.00063 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ27164.1 - 5.9e-05 22.7 1.5 0.2 11.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ27164.1 - 0.00016 21.7 0.4 0.019 14.9 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 OAJ27164.1 - 0.00016 21.6 0.1 0.43 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ27164.1 - 0.0025 17.9 0.2 3.5 7.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ27164.1 - 0.0031 17.8 0.5 2.3 8.5 0.4 3.0 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 OAJ27164.1 - 0.017 15.0 0.3 4 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 OAJ27164.1 - 0.04 14.4 1.1 7.2 7.1 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.6 OAJ27164.1 - 0.067 13.7 0.3 0.47 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhnG PF06754.12 OAJ27164.1 - 0.14 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG TsaE PF02367.17 OAJ27164.1 - 0.22 11.5 1.3 3.9 7.5 0.2 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAJ27164.1 - 0.24 11.6 3.9 0.1 12.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAJ27164.1 - 0.83 9.3 9.3 2.3 7.9 0.9 3.6 4 1 0 4 4 4 0 AAA domain DPBB_1 PF03330.18 OAJ27175.1 - 0.066 13.5 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 Lytic transglycolase DUF3402 PF11882.8 OAJ27177.1 - 4.6e-120 401.9 0.0 1.1e-115 387.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 OAJ27177.1 - 1.5e-60 204.8 0.0 3.3e-60 203.7 0.0 1.5 1 1 0 1 1 1 1 N1221-like protein RVT_2 PF07727.14 OAJ27180.1 - 5.3e-73 245.6 0.0 7.4e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ27180.1 - 2e-11 44.1 0.0 1.2e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ27180.1 - 5.9e-06 26.0 0.0 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Crr6 PF08847.11 OAJ27180.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 HMG_box PF00505.19 OAJ27181.1 - 3.8e-06 27.2 1.3 5.6e-05 23.5 1.3 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box PF00505.19 OAJ27182.1 - 1.4e-08 35.0 3.4 0.00013 22.3 1.7 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ27182.1 - 0.0039 17.7 0.9 0.0091 16.6 0.9 1.6 1 0 0 1 1 1 1 HMG-box domain Proteasome PF00227.26 OAJ27184.1 - 2e-33 115.5 0.0 2.4e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TPR_17 PF13431.6 OAJ27185.1 - 5.3e-06 26.5 0.5 0.24 11.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ27185.1 - 0.00017 21.4 15.0 0.19 12.0 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ27185.1 - 0.0025 17.6 0.9 2.9 7.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ27185.1 - 0.018 15.5 0.1 22 5.6 0.0 4.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ27185.1 - 0.022 15.0 0.0 23 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ27185.1 - 0.11 12.7 1.3 0.39 11.0 0.7 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAJ27185.1 - 0.15 13.0 12.7 0.17 12.8 0.2 6.5 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ27185.1 - 2.4 8.5 14.8 1.8 8.9 0.2 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ27185.1 - 8.7 6.6 9.1 19 5.5 0.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 OAJ27186.1 - 1.7e-32 111.9 0.0 9.5e-32 109.5 0.0 2.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 OAJ27186.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 PS_Dcarbxylase PF02666.15 OAJ27188.1 - 3.9e-73 245.3 0.0 1.5e-55 187.9 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 OAJ27188.1 - 0.00091 18.9 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 MNLL subunit Y_phosphatase2 PF03162.13 OAJ27189.1 - 9.7e-46 155.4 0.0 1.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex2_Pex12 PF04757.14 OAJ27189.1 - 6.5e-35 120.8 3.7 1e-34 120.1 3.7 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Y_phosphatase3 PF13350.6 OAJ27189.1 - 9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myc_N PF01056.18 OAJ27189.1 - 0.19 11.6 2.9 5.4 6.8 0.4 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF1168 PF06658.12 OAJ27189.1 - 4.4 7.1 11.5 8.4 6.2 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF5421 PF17458.2 OAJ27189.1 - 4.5 6.6 6.4 0.41 10.0 1.9 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Kinesin PF00225.23 OAJ27190.1 - 2.3e-110 368.6 0.0 3.3e-110 368.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ27190.1 - 6.5e-24 84.6 0.0 1.3e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding GPS2_interact PF15784.5 OAJ27190.1 - 0.08 13.4 0.8 0.24 11.9 0.2 2.0 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Myosin_tail_1 PF01576.19 OAJ27190.1 - 0.094 10.5 4.9 0.14 9.9 4.9 1.1 1 0 0 1 1 1 0 Myosin tail MSL1_dimer PF16801.5 OAJ27190.1 - 0.23 11.3 2.9 0.44 10.4 2.9 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Seryl_tRNA_N PF02403.22 OAJ27190.1 - 0.81 9.9 6.4 0.93 9.8 3.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 OAJ27190.1 - 4 7.8 5.4 33 4.8 0.6 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain DnaJ PF00226.31 OAJ27191.1 - 1.7e-15 56.9 0.3 2.9e-15 56.1 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain JAB PF01398.21 OAJ27192.1 - 2.2e-32 111.5 0.1 4.5e-32 110.5 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAJ27192.1 - 1.6e-15 57.5 0.4 3.2e-15 56.5 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAJ27192.1 - 4.9e-06 26.3 0.0 8.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 OAJ27192.1 - 0.029 14.5 0.1 0.059 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) PIG-F PF06699.11 OAJ27194.1 - 1.4e-15 58.0 10.6 4.6e-15 56.2 10.2 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Suc_Fer-like PF06999.12 OAJ27195.1 - 4.1e-44 150.8 0.0 8.9e-44 149.7 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like MAGI_u5 PF16666.5 OAJ27195.1 - 0.0088 16.2 1.8 0.0088 16.2 1.8 1.7 1 1 0 1 1 1 1 Unstructured region on MAGI BAR_2 PF10455.9 OAJ27195.1 - 0.053 12.7 1.2 0.079 12.1 1.2 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2347 PF09804.9 OAJ27195.1 - 0.17 11.5 1.9 0.26 10.9 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF3552 PF12072.8 OAJ27195.1 - 0.23 10.8 6.3 0.38 10.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tau95 PF09734.9 OAJ27196.1 - 1.4e-27 97.2 0.2 3e-27 96.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OAJ27196.1 - 7.2e-15 55.3 0.1 6.5e-14 52.2 0.0 2.7 2 1 0 2 2 2 1 Tau95 Triple barrel domain RPN2_C PF18004.1 OAJ27196.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Mannosyl_trans2 PF04188.13 OAJ27197.1 - 3.8e-54 184.7 5.8 4.9e-54 184.3 5.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) GSAP-16 PF14959.6 OAJ27197.1 - 0.011 15.6 0.2 0.019 14.8 0.2 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term NAD_binding_7 PF13241.6 OAJ27198.1 - 2.5e-27 95.3 0.0 4.2e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAJ27198.1 - 7.3e-25 86.4 0.6 1.2e-24 85.7 0.6 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAJ27198.1 - 6.8e-13 47.8 0.9 2e-12 46.3 0.2 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central 2OG-FeII_Oxy PF03171.20 OAJ27200.1 - 1.5e-11 44.7 0.1 1.3e-10 41.7 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAJ27200.1 - 5.7e-11 43.2 0.2 1.2e-10 42.2 0.2 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RasGEF PF00617.19 OAJ27201.1 - 2.2e-57 194.1 0.1 4.9e-57 193.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ27201.1 - 2.1e-25 89.0 0.1 2.1e-25 89.0 0.1 3.3 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 OAJ27201.1 - 4.1e-13 48.7 0.1 8.6e-13 47.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ27201.1 - 6.9e-13 48.2 0.1 1.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ27201.1 - 9.5e-12 44.4 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 OAJ27201.1 - 1.8e-05 24.8 3.8 0.076 13.1 0.2 2.6 2 0 0 2 2 2 2 WW domain DUF2722 PF10846.8 OAJ27201.1 - 0.0028 16.7 7.4 0.0028 16.7 7.4 4.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) PQQ PF01011.21 OAJ27201.1 - 0.0044 16.9 0.1 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 PQQ enzyme repeat TPR_1 PF00515.28 OAJ27202.1 - 4.1e-45 149.8 28.9 2.4e-05 24.0 0.2 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat STI1 PF17830.1 OAJ27202.1 - 5.5e-34 115.9 14.0 7e-18 64.3 0.7 3.5 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 OAJ27202.1 - 7.4e-31 103.8 34.6 0.0068 16.4 0.1 10.2 11 0 0 11 11 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ27202.1 - 4.4e-22 76.4 28.8 0.0021 18.1 0.0 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ27202.1 - 9.3e-22 76.4 26.6 5.4e-06 26.0 0.4 9.4 7 2 2 9 9 9 6 TPR repeat TPR_12 PF13424.6 OAJ27202.1 - 1.7e-18 66.7 26.5 2.9e-10 40.3 0.5 7.1 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ27202.1 - 3.3e-15 55.5 18.5 0.055 14.3 0.0 9.7 3 3 6 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ27202.1 - 1.3e-14 54.5 33.7 8.6e-06 26.3 1.3 8.1 4 3 4 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ27202.1 - 1.5e-09 38.2 22.1 3.4e-05 24.3 0.4 6.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ27202.1 - 9.1e-09 35.1 5.4 0.037 14.4 0.1 6.9 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ27202.1 - 7.1e-08 32.0 9.8 0.015 15.3 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ27202.1 - 3.9e-07 29.7 17.7 1.7 8.6 0.1 8.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ27202.1 - 1.8e-06 28.0 9.2 0.025 14.7 0.0 5.3 3 2 2 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ27202.1 - 7.7e-05 23.1 18.6 0.81 10.5 0.0 7.9 9 0 0 9 9 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ27202.1 - 0.014 15.6 1.6 0.014 15.6 1.6 4.2 3 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 OAJ27202.1 - 0.035 12.8 3.1 0.039 12.7 0.0 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.6 OAJ27202.1 - 0.039 14.0 3.0 4.3 7.5 0.1 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat XPC-binding PF09280.11 OAJ27202.1 - 0.088 12.6 5.8 0.28 10.9 3.2 3.1 3 0 0 3 3 3 0 XPC-binding domain DUF3856 PF12968.7 OAJ27202.1 - 0.21 11.6 10.8 7.5 6.6 1.2 4.9 2 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) Coat_F PF07875.12 OAJ27202.1 - 0.26 11.5 2.0 0.75 10.1 0.1 2.7 2 0 0 2 2 2 0 Coat F domain RNase_PH PF01138.21 OAJ27203.1 - 1.6e-19 70.7 0.0 3.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ27203.1 - 3.8e-05 23.6 0.0 9.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3889 PF13028.6 OAJ27203.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) WD40 PF00400.32 OAJ27204.1 - 1.1e-14 54.6 0.7 0.011 16.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27204.1 - 9.1e-08 32.3 0.0 0.028 14.7 0.0 4.7 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain ARHGEF5_35 PF15441.6 OAJ27204.1 - 0.072 12.1 1.0 0.1 11.6 1.0 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Ribosomal_S13 PF00416.22 OAJ27205.1 - 4.3e-51 172.6 1.9 5.1e-51 172.4 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 OAJ27205.1 - 0.022 15.0 0.0 0.068 13.4 0.0 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.11 OAJ27205.1 - 0.046 12.5 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 OAJ27205.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Bromodomain PF00439.25 OAJ27206.1 - 2.5e-17 62.7 0.1 6.3e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M1 PF01433.20 OAJ27206.1 - 7.7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 OAJ27206.1 - 0.00014 22.2 1.2 0.3 11.5 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats Peptidase_M1_N PF17900.1 OAJ27206.1 - 0.034 14.3 0.5 2.5 8.3 0.0 2.7 3 0 0 3 3 3 0 Peptidase M1 N-terminal domain Glyco_hydro_31 PF01055.26 OAJ27207.1 - 2.9e-131 438.7 1.3 3.7e-131 438.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAJ27207.1 - 1.1e-22 80.1 0.2 2.9e-21 75.5 0.0 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAJ27207.1 - 0.00076 19.7 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF4006 PF13179.6 OAJ27209.1 - 1 9.3 3.2 0.29 11.1 0.4 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Arm PF00514.23 OAJ27210.1 - 9.4e-06 25.5 15.7 0.035 14.2 0.0 9.3 10 0 0 10 10 10 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 OAJ27210.1 - 0.0031 16.8 0.0 5.9 6.1 0.0 3.7 3 1 0 4 4 4 1 V-ATPase subunit H HEAT_2 PF13646.6 OAJ27210.1 - 0.0065 16.8 11.6 4.7 7.7 0.0 6.2 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.22 OAJ27210.1 - 0.079 13.3 12.5 1.1e+02 3.5 0.0 7.3 7 0 0 7 7 7 0 HEAT repeat Nup192 PF11894.8 OAJ27210.1 - 0.24 8.5 0.0 0.34 8.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 EAF PF09816.9 OAJ27212.1 - 1.7e-14 54.0 0.0 5.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NOA36 PF06524.12 OAJ27212.1 - 5.1e-05 22.7 5.0 5.1e-05 22.7 5.0 3.0 2 1 0 2 2 2 1 NOA36 protein Nop14 PF04147.12 OAJ27212.1 - 0.053 11.7 44.7 0.009 14.3 8.8 2.0 2 0 0 2 2 2 0 Nop14-like family ALMT PF11744.8 OAJ27212.1 - 3.3 6.4 3.7 5 5.8 3.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter BSP_II PF05432.11 OAJ27212.1 - 3.5 7.2 37.9 0.53 9.9 7.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ATP-synt_ab PF00006.25 OAJ27213.1 - 1.1e-62 211.4 0.2 2.2e-62 210.5 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAJ27213.1 - 3.4e-24 85.1 3.6 4.9e-24 84.6 2.4 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 OAJ27213.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAJ27213.1 - 0.011 15.0 0.6 0.017 14.3 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 OAJ27213.1 - 0.014 15.3 0.6 0.025 14.5 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 OAJ27213.1 - 0.024 14.0 0.2 0.04 13.3 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OAJ27213.1 - 0.029 14.7 0.1 0.11 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OAJ27213.1 - 0.053 14.0 0.0 0.28 11.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ27213.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAJ27213.1 - 0.084 13.2 0.6 0.34 11.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ27213.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Complex1_LYR PF05347.15 OAJ27214.1 - 3.1e-05 24.0 0.6 5.8e-05 23.0 0.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4505 PF14956.6 OAJ27215.1 - 8.6e-31 107.0 0.0 2.3e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Axin_b-cat_bind PF08833.10 OAJ27215.1 - 0.69 10.1 2.7 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Axin beta-catenin binding domain DNA_pol3_delta2 PF13177.6 OAJ27216.1 - 2.8e-11 43.5 0.0 7.7e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAJ27216.1 - 9.1e-05 22.9 0.2 0.00029 21.3 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ27216.1 - 0.0066 16.9 0.1 0.044 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAJ27216.1 - 0.007 16.5 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAJ27216.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 OAJ27216.1 - 0.014 15.7 0.1 0.06 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 OAJ27216.1 - 0.026 14.9 0.0 0.075 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DUF1254 PF06863.12 OAJ27216.1 - 0.028 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Rep_fac_C PF08542.11 OAJ27216.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 Replication factor C C-terminal domain RuvB_N PF05496.12 OAJ27216.1 - 0.055 13.2 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rubis-subs-bind PF09273.11 OAJ27217.1 - 6.3e-13 49.5 0.0 1.3e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OAJ27217.1 - 1.3e-12 48.4 0.0 3e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 SET domain CENP-B_dimeris PF09026.10 OAJ27217.1 - 0.27 11.6 4.7 0.56 10.6 4.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PGA2 PF07543.12 OAJ27221.1 - 1 9.3 6.4 0.48 10.4 1.9 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Iwr1 PF08574.10 OAJ27221.1 - 1.9 9.5 8.5 1.3 10.1 6.5 1.9 2 0 0 2 2 2 0 Transcription factor Iwr1 TRP PF06011.12 OAJ27222.1 - 3.8e-28 98.4 17.0 1.2e-20 73.7 15.2 2.4 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel AA_permease PF00324.21 OAJ27223.1 - 1.5e-127 426.1 37.1 1.8e-127 425.8 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ27223.1 - 2.2e-39 135.5 41.4 2.7e-39 135.2 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ27224.1 - 9.1e-136 453.2 47.6 1.1e-135 453.0 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ27224.1 - 2.5e-38 132.0 50.4 3.1e-38 131.7 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3093 PF11292.8 OAJ27224.1 - 0.06 13.6 0.2 0.06 13.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3093) YpmT PF17431.2 OAJ27224.1 - 0.27 11.3 3.0 0.3 11.1 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized YmpT-like DnaJ_C PF01556.18 OAJ27225.1 - 2.7e-41 141.1 1.2 3.7e-41 140.7 1.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ27225.1 - 3.8e-21 75.0 0.2 6.6e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ27225.1 - 6.1e-16 58.5 19.7 9.8e-16 57.9 19.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAJ27225.1 - 0.0045 16.9 9.5 0.019 14.9 1.1 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAJ27225.1 - 6 6.9 12.2 7.4 6.6 3.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TetR_C_15 PF17918.1 OAJ27226.1 - 0.58 10.9 3.2 0.61 10.9 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain FAD_binding_3 PF01494.19 OAJ27227.1 - 2.9e-55 187.9 0.3 1.2e-54 185.9 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAJ27227.1 - 3.2e-18 66.3 0.0 5.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 OAJ27227.1 - 6.3e-06 26.3 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ27227.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ27227.1 - 0.00017 20.9 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ27227.1 - 0.00028 19.7 0.1 0.00043 19.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAJ27227.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAJ27227.1 - 0.0025 17.0 0.3 0.0039 16.3 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 OAJ27227.1 - 0.0028 16.6 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 OAJ27227.1 - 0.004 16.3 0.5 0.004 16.3 0.5 1.8 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ27227.1 - 0.0042 17.6 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ27227.1 - 0.013 14.7 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ27227.1 - 0.037 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ27227.1 - 0.076 13.3 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAJ27227.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAJ27227.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3602 PF12223.8 OAJ27228.1 - 7e-12 45.8 18.8 3.9e-08 33.8 4.6 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) DUF1776 PF08643.10 OAJ27229.1 - 0.0013 18.2 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAJ27229.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Spt20 PF12090.8 OAJ27229.1 - 3.7 7.1 21.2 1.5 8.3 9.2 2.4 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 OAJ27229.1 - 4.7 5.9 8.6 2.1 7.0 0.4 2.2 2 0 0 2 2 2 0 Presenilin LIP PF03583.14 OAJ27230.1 - 7.3e-58 196.1 0.1 9.5e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.13 OAJ27231.1 - 1.8e-19 70.4 0.0 2.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ27231.1 - 2.1e-09 36.7 0.0 0.00041 19.3 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase CsgF PF10614.9 OAJ27232.1 - 1.4 9.2 4.0 0.51 10.6 0.8 1.8 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Asp PF00026.23 OAJ27233.1 - 2.2e-46 158.8 0.6 6.9e-46 157.1 0.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ27233.1 - 4.9e-07 30.2 1.1 0.015 15.5 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ27233.1 - 0.0005 20.7 0.4 0.25 12.0 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ27233.1 - 0.0014 19.2 0.1 0.055 14.0 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAJ27233.1 - 0.0054 16.5 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 OAJ27234.1 - 1.5e-45 156.0 0.2 8e-45 153.6 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ27234.1 - 2.2e-06 28.0 2.9 0.027 14.7 1.3 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ27234.1 - 7.2e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAP_C PF03943.13 OAJ27236.1 - 3.1e-13 49.1 0.1 5.6e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 OAJ27236.1 - 4.5e-05 23.7 2.4 0.0018 18.6 0.5 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAJ27236.1 - 0.00016 21.2 0.0 0.53 9.8 0.0 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OAJ27236.1 - 0.11 12.3 1.2 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat Tti2 PF10521.9 OAJ27237.1 - 8.4e-17 61.6 0.0 9.4e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 Tti2 family MAP65_ASE1 PF03999.12 OAJ27238.1 - 1.9e-41 142.5 1.7 1.4e-39 136.3 0.2 2.1 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Apolipoprotein PF01442.18 OAJ27238.1 - 0.15 12.0 12.0 0.85 9.5 12.0 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Glyco_transf_22 PF03901.17 OAJ27239.1 - 2.9e-70 237.6 14.7 2.2e-68 231.4 14.3 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family nlz1 PF12402.8 OAJ27239.1 - 0.094 13.2 0.9 20 5.7 0.2 3.1 3 0 0 3 3 3 0 NocA-like zinc-finger protein 1 WW PF00397.26 OAJ27240.1 - 5e-06 26.5 0.5 9.5e-06 25.6 0.5 1.5 1 0 0 1 1 1 1 WW domain DEAD PF00270.29 OAJ27255.1 - 2.5e-48 164.2 0.1 4.2e-47 160.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ27255.1 - 1.1e-29 102.9 0.0 1.8e-28 99.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Glyco_hydro_2 PF00703.21 OAJ27255.1 - 0.21 12.3 1.1 0.9 10.2 1.1 2.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Na_Ca_ex PF01699.24 OAJ27256.1 - 1.2e-18 67.5 36.4 5.2e-11 42.7 17.1 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 OAJ27256.1 - 1.7e-15 57.4 3.8 1.7e-15 57.4 3.8 3.7 3 0 0 3 3 3 1 Inner membrane component domain DUF4906 PF16249.5 OAJ27256.1 - 1.3 8.8 3.0 2.9 7.7 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) SLATT_5 PF18160.1 OAJ27256.1 - 2.7 7.3 3.6 4.9 6.4 2.3 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Lipase_3 PF01764.25 OAJ27257.1 - 3e-06 27.2 0.1 1.4e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 Lipase (class 3) Pex14_N PF04695.13 OAJ27257.1 - 3.4 8.3 17.0 0.34 11.6 3.7 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctf8 PF09696.10 OAJ27258.1 - 0.0002 21.7 1.9 0.00031 21.1 0.2 2.4 2 1 0 2 2 2 1 Ctf8 TFIIA PF03153.13 OAJ27258.1 - 0.0017 18.4 0.9 0.0017 18.4 0.9 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2273 PF10031.9 OAJ27258.1 - 0.06 13.4 2.3 0.13 12.3 2.3 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Nop14 PF04147.12 OAJ27258.1 - 0.1 10.8 12.8 0.052 11.8 8.8 1.9 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.6 OAJ27258.1 - 0.14 11.9 9.3 46 3.7 0.0 3.4 3 0 0 3 3 3 0 FAM176 family SpoIIIAH PF12685.7 OAJ27258.1 - 0.29 10.9 6.1 2.5 7.9 0.4 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein SDA1 PF05285.12 OAJ27258.1 - 0.32 10.4 18.5 0.026 13.9 5.5 2.2 2 0 0 2 2 2 0 SDA1 Apt1 PF10351.9 OAJ27258.1 - 0.33 9.7 7.8 1.6 7.5 0.7 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Otopetrin PF03189.13 OAJ27258.1 - 1.8 7.3 2.7 11 4.8 2.7 1.9 1 1 0 1 1 1 0 Otopetrin GCIP PF13324.6 OAJ27258.1 - 4.4 6.8 6.4 8 6.0 6.4 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting YL1 PF05764.13 OAJ27258.1 - 4.6 7.3 15.0 3.7 7.6 11.2 2.4 2 0 0 2 2 2 0 YL1 nuclear protein TOH_N PF12549.8 OAJ27259.1 - 0.11 12.4 0.6 1.1e+02 2.8 0.0 3.3 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal Lipase_3 PF01764.25 OAJ27260.1 - 8.2e-13 48.4 0.0 3.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) RVT_3 PF13456.6 OAJ27261.1 - 0.0056 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Amidase PF01425.21 OAJ27263.1 - 3.8e-96 322.8 0.0 7.8e-96 321.8 0.0 1.5 1 1 0 1 1 1 1 Amidase Pyrid_oxidase_2 PF13883.6 OAJ27264.1 - 2.8e-25 89.2 0.0 3.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kelch_2 PF07646.15 OAJ27264.1 - 0.046 13.7 0.8 1.8 8.7 0.4 2.9 2 1 0 2 2 2 0 Kelch motif GDI PF00996.18 OAJ27265.1 - 1.7e-205 682.6 0.0 2.2e-205 682.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAJ27265.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 OAJ27266.1 - 8.9e-22 77.5 0.0 2.8e-21 75.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_3_Rpc31 PF11705.8 OAJ27267.1 - 0.00035 20.9 2.7 0.0012 19.2 2.7 1.9 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TB2_DP1_HVA22 PF03134.19 OAJ27268.1 - 5.2e-29 100.0 4.6 5.2e-29 100.0 4.6 1.4 2 0 0 2 2 2 1 TB2/DP1, HVA22 family FbpC_C_terminal PF17845.1 OAJ27269.1 - 0.15 12.2 0.1 20 5.4 0.0 3.0 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain DDE_3 PF13358.6 OAJ27270.1 - 1e-26 93.4 0.0 1.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ27270.1 - 2e-07 30.6 0.0 3.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.11 OAJ27270.1 - 2.6e-05 23.4 0.1 0.0029 16.6 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain rve PF00665.26 OAJ27270.1 - 0.00063 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 OAJ27270.1 - 0.0013 19.3 0.4 0.004 17.7 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain ECH_1 PF00378.20 OAJ27271.1 - 8.4e-48 162.9 0.0 2.2e-41 141.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ27271.1 - 2e-25 90.0 0.1 1.9e-16 60.5 0.0 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 OAJ27272.1 - 2.2e-62 211.0 0.0 2.8e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ27272.1 - 6.9e-13 49.4 0.2 6.5e-12 46.3 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OAJ27273.1 - 7e-84 281.9 0.0 9.4e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ27273.1 - 2.2e-10 41.4 0.0 8.6e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pil1 PF13805.6 OAJ27274.1 - 7.8e-13 48.5 2.5 2.1e-12 47.1 2.5 1.7 1 0 0 1 1 1 1 Eisosome component PIL1 FHA PF00498.26 OAJ27277.1 - 2.3e-08 34.2 0.0 3.4e-07 30.5 0.0 2.3 1 1 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.9 OAJ27278.1 - 2.1e-56 190.9 0.0 5.5e-56 189.5 0.0 1.7 1 0 0 1 1 1 1 Gti1/Pac2 family AMP-binding PF00501.28 OAJ27279.1 - 2.9e-07 29.5 0.0 3.3e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GSHPx PF00255.19 OAJ27280.1 - 1.3e-32 111.6 0.1 1.7e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 OAJ27280.1 - 5.4e-05 22.9 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ27280.1 - 0.00041 20.3 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Acyl-CoA_dh_1 PF00441.24 OAJ27281.1 - 3.2e-31 108.6 0.2 5.1e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ27281.1 - 8.2e-17 61.2 0.2 1.8e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 OAJ27281.1 - 2.4e-16 59.6 0.0 5.9e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 OAJ27281.1 - 5.1e-15 56.1 0.2 7.3e-14 52.4 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ27281.1 - 1.1e-06 29.0 0.2 1.8e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyto_heme_lyase PF01265.17 OAJ27282.1 - 2.3e-69 234.2 18.0 1.1e-54 186.0 11.0 3.1 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MMtag PF10159.9 OAJ27283.1 - 1.7e-30 105.2 2.2 1.7e-30 105.2 2.2 2.9 2 1 0 2 2 2 1 Multiple myeloma tumor-associated DUF4042 PF13251.6 OAJ27284.1 - 3.1e-09 36.8 4.2 1.3e-08 34.8 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 OAJ27284.1 - 0.0013 19.1 33.3 0.018 15.4 3.8 6.7 4 2 3 7 7 7 5 HEAT repeats SAM_DrpA PF18255.1 OAJ27284.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain HEAT PF02985.22 OAJ27284.1 - 0.1 12.9 36.2 2.9 8.4 0.5 9.6 10 0 0 10 10 10 0 HEAT repeat HEAT_EZ PF13513.6 OAJ27284.1 - 1.1 9.9 31.7 0.49 10.9 0.4 7.5 7 1 2 9 9 9 0 HEAT-like repeat PQ-loop PF04193.14 OAJ27285.1 - 4.2e-14 52.1 0.2 2.4e-12 46.4 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Amidinotransf PF02274.17 OAJ27286.1 - 8e-13 48.2 0.0 7.8e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 Amidinotransferase Transket_pyr PF02779.24 OAJ27287.1 - 4.9e-60 202.2 0.0 8.2e-60 201.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OAJ27287.1 - 2.1e-45 155.0 0.0 7.2e-45 153.2 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OAJ27287.1 - 1.4e-36 125.5 0.0 2.1e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Pkinase PF00069.25 OAJ27288.1 - 8.8e-43 146.6 0.0 1.5e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27288.1 - 9.3e-18 64.4 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAJ27288.1 - 0.0038 16.9 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ27288.1 - 0.0078 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF294_C PF10335.9 OAJ27288.1 - 0.027 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Kinase-like PF14531.6 OAJ27288.1 - 0.057 12.7 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DAHP_synth_1 PF00793.20 OAJ27289.1 - 1.2e-98 329.3 0.0 1.5e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF3915 PF13054.6 OAJ27290.1 - 0.13 12.2 3.4 0.26 11.3 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) HECT PF00632.25 OAJ27291.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) Ribosomal_L4 PF00573.22 OAJ27292.1 - 7e-40 136.8 0.3 7e-40 136.8 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAJ27292.1 - 1.2e-27 95.8 0.2 1.2e-27 95.8 0.2 2.4 4 0 0 4 4 4 1 60S ribosomal protein L4 C-terminal domain U79_P34 PF03064.16 OAJ27292.1 - 0.1 11.9 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pox_Ag35 PF03286.14 OAJ27293.1 - 0.0058 16.4 2.7 0.012 15.4 0.8 2.2 2 0 0 2 2 2 1 Pox virus Ag35 surface protein AAA PF00004.29 OAJ27294.1 - 3.3e-47 160.2 0.0 2.3e-41 141.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ27294.1 - 4.1e-09 36.1 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ27294.1 - 2.7e-07 31.1 0.2 4.1e-05 24.0 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OAJ27294.1 - 1.4e-05 25.2 0.0 4.9e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAJ27294.1 - 7.3e-05 22.6 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAJ27294.1 - 9.7e-05 22.5 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ27294.1 - 0.0021 18.0 0.0 0.0084 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAJ27294.1 - 0.0046 16.7 0.0 0.91 9.2 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 OAJ27294.1 - 0.007 16.6 0.9 0.099 12.9 0.2 3.2 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 OAJ27294.1 - 0.017 15.2 0.6 0.052 13.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 OAJ27294.1 - 0.022 15.3 0.0 0.068 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ27294.1 - 0.022 15.2 0.1 0.15 12.6 0.0 2.4 3 0 0 3 3 2 0 ABC transporter ResIII PF04851.15 OAJ27294.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAJ27294.1 - 0.03 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 OAJ27294.1 - 0.046 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Bromodomain AAA_7 PF12775.7 OAJ27294.1 - 0.05 13.1 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 OAJ27294.1 - 0.06 12.9 2.2 0.15 11.6 0.0 2.7 4 0 0 4 4 2 0 AAA domain RNA_helicase PF00910.22 OAJ27294.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 OAJ27294.1 - 0.094 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 OAJ27294.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OAJ27294.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 OAJ27294.1 - 0.12 12.4 0.1 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_14 PF13173.6 OAJ27294.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAJ27294.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain PHD PF00628.29 OAJ27296.1 - 4e-10 39.4 8.1 7.5e-10 38.6 8.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 OAJ27296.1 - 1.6e-05 24.8 3.2 8.8e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.6 OAJ27296.1 - 0.21 11.2 2.5 0.39 10.3 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 OAJ27297.1 - 7.2e-31 106.6 6.5 7.2e-31 106.6 6.5 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 OAJ27297.1 - 2.2e-23 83.4 0.3 2.2e-23 83.4 0.3 3.9 3 0 0 3 3 3 2 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OAJ27297.1 - 1.5e-22 79.6 5.7 1.5e-22 79.6 5.7 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 OAJ27297.1 - 7.6e-20 70.8 0.1 1.5e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 OAJ27297.1 - 4.3e-13 48.6 1.9 4.3e-13 48.6 1.9 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 OAJ27297.1 - 1.3e-10 41.6 0.9 3.4e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 OAJ27297.1 - 1.8e-09 37.3 8.8 1.8e-09 37.3 8.8 2.7 2 0 0 2 2 2 1 PHD-finger 4HBT PF03061.22 OAJ27298.1 - 4.5e-11 43.0 0.0 8.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAJ27298.1 - 0.0041 17.4 0.0 0.008 16.5 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF3659 PF12396.8 OAJ27298.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) DnaJ_C PF01556.18 OAJ27299.1 - 1.8e-29 102.7 0.0 2.8e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ27299.1 - 3.7e-26 91.0 1.4 5.8e-26 90.4 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OAJ27299.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein MFS_1 PF07690.16 OAJ27300.1 - 2.8e-31 108.7 28.8 2.8e-31 108.7 28.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily COX6C PF02937.15 OAJ27300.1 - 0.1 12.7 1.3 2.1 8.5 0.0 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc Vpu PF00558.19 OAJ27300.1 - 0.3 10.9 1.4 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Vpu protein Prominin PF05478.11 OAJ27300.1 - 8.8 4.1 7.7 9.3 4.1 6.6 1.5 2 0 0 2 2 2 0 Prominin Helicase_C PF00271.31 OAJ27301.1 - 1.5e-18 67.1 0.0 2.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Menin PF05053.13 OAJ27301.1 - 0.55 8.5 2.9 0.77 8.0 2.9 1.2 1 0 0 1 1 1 0 Menin PBP1_TM PF14812.6 OAJ27301.1 - 0.55 10.6 7.2 3.1 8.2 7.2 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ27301.1 - 0.87 8.8 5.0 1.5 8.1 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ27301.1 - 2.5 6.3 6.7 3.8 5.7 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OAJ27301.1 - 3.6 7.3 4.6 8.1 6.1 4.6 1.6 1 0 0 1 1 1 0 FAM176 family DCB PF16213.5 OAJ27302.1 - 1.5e-42 145.3 8.1 5.8e-42 143.4 8.1 2.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OAJ27302.1 - 7.6e-41 139.7 7.5 1.7e-40 138.5 0.1 3.9 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 OAJ27302.1 - 2.8e-26 92.0 8.0 6.3e-15 54.4 4.5 3.7 4 1 0 4 4 4 3 C-terminal region of Mon2 protein RTP1_C1 PF10363.9 OAJ27302.1 - 0.0029 17.8 0.1 1.3 9.3 0.0 3.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1981 PF09324.10 OAJ27302.1 - 0.0043 16.9 0.0 0.055 13.3 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Urb2 PF10441.9 OAJ27302.1 - 3.2 7.6 12.3 0.27 11.1 0.2 4.4 5 0 0 5 5 5 0 Urb2/Npa2 family Cyclin PF08613.11 OAJ27303.1 - 2e-29 103.0 0.9 4.1e-29 102.0 0.6 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAJ27303.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain OST3_OST6 PF04756.13 OAJ27304.1 - 2.6e-79 266.6 0.0 3.5e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 OAJ27304.1 - 0.0033 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Pribosyltran PF00156.27 OAJ27305.1 - 2.2e-17 63.0 0.3 3.1e-17 62.5 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NABP PF07990.12 OAJ27305.1 - 0.0062 16.1 0.1 0.0085 15.7 0.1 1.1 1 0 0 1 1 1 1 Nucleic acid binding protein NABP OTU PF02338.19 OAJ27306.1 - 1.4e-19 70.8 0.0 2.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3618 PF12277.8 OAJ27306.1 - 0.087 13.1 5.8 0.49 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Halo_GVPC PF05465.13 OAJ27306.1 - 0.54 10.6 0.1 0.54 10.6 0.1 2.4 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat 3Beta_HSD PF01073.19 OAJ27307.1 - 6.8e-60 202.4 0.0 1.4e-55 188.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ27307.1 - 1.9e-23 83.2 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ27307.1 - 1.4e-10 41.1 0.0 4.4e-08 32.9 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAJ27307.1 - 2.1e-09 37.5 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAJ27307.1 - 8.1e-09 35.0 0.1 6.1e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAJ27307.1 - 8.3e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OAJ27307.1 - 0.00072 19.5 0.1 0.0053 16.7 0.1 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ27307.1 - 0.0058 15.8 0.1 0.028 13.6 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 OAJ27307.1 - 0.0064 16.7 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 OAJ27307.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family UBA_3 PF09288.10 OAJ27307.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DNA_pol_B_exo1 PF03104.19 OAJ27307.1 - 0.26 10.4 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Cofilin_ADF PF00241.20 OAJ27308.1 - 1.6e-18 66.7 0.0 1e-08 35.0 0.0 2.7 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Secretin_N PF03958.17 OAJ27308.1 - 0.041 14.3 6.3 0.52 10.8 0.0 3.9 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain MeaB PF03308.16 OAJ27309.1 - 5.1e-06 25.7 0.1 8.1e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OAJ27309.1 - 0.0001 22.8 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OAJ27309.1 - 0.00012 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OAJ27309.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 OAJ27309.1 - 0.0024 17.8 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 OAJ27309.1 - 0.0032 16.7 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 OAJ27309.1 - 0.0045 17.4 0.0 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 OAJ27309.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 OAJ27309.1 - 0.006 15.9 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.13 OAJ27309.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OAJ27309.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 OAJ27309.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ27309.1 - 0.047 14.2 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 OAJ27309.1 - 0.048 13.7 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAJ27309.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAJ27309.1 - 0.074 13.0 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 OAJ27309.1 - 0.076 13.4 0.1 0.32 11.4 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ27309.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_35 PF14516.6 OAJ27309.1 - 0.088 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 OAJ27309.1 - 0.099 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ27309.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ27309.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RPE65 PF03055.15 OAJ27310.1 - 4.7e-96 322.8 0.0 1e-95 321.7 0.0 1.5 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein Eisosome1 PF12757.7 OAJ27310.1 - 0.028 14.7 1.9 0.049 13.9 1.9 1.3 1 0 0 1 1 1 0 Eisosome protein 1 Syja_N PF02383.18 OAJ27311.1 - 2.5e-78 263.6 0.0 3.7e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Phosphoesterase PF04185.14 OAJ27312.1 - 1.7e-26 93.3 3.2 1.1e-25 90.6 3.2 1.9 1 1 0 1 1 1 1 Phosphoesterase family Calcipressin PF04847.12 OAJ27312.1 - 0.0081 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Calcipressin Histone_H2A_C PF16211.5 OAJ27313.1 - 1.7e-18 66.0 0.7 3.4e-18 65.1 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ27313.1 - 6.7e-17 62.1 0.0 1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ27313.1 - 1.1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ING PF12998.7 OAJ27314.1 - 5e-13 49.5 0.5 8.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ27314.1 - 1.7e-05 24.6 10.6 2.9e-05 23.9 10.6 1.4 1 0 0 1 1 1 1 PHD-finger Menin PF05053.13 OAJ27314.1 - 6.3 5.0 9.7 15 3.8 9.7 1.5 1 0 0 1 1 1 0 Menin Histone PF00125.24 OAJ27315.1 - 1.6e-22 80.3 0.2 2.1e-22 79.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ27315.1 - 5e-07 29.9 0.1 9.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAJ27315.1 - 0.00044 20.7 0.0 0.0007 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 OAJ27315.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 OAJ27315.1 - 0.066 13.2 0.1 0.077 13.0 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein RP-C PF03428.13 OAJ27315.1 - 0.099 12.3 0.2 0.26 10.9 0.2 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain FGAR-AT_linker PF18072.1 OAJ27316.1 - 2.2e-19 69.7 0.0 3.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Trehalase PF01204.18 OAJ27317.1 - 1.5e-172 575.0 0.2 1.9e-172 574.7 0.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAJ27317.1 - 2.9e-16 58.9 0.1 4.8e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cpn60_TCP1 PF00118.24 OAJ27318.1 - 4e-154 513.9 2.2 4.5e-154 513.7 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 OAJ27318.1 - 0.77 9.9 4.2 15 5.7 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_caries-ASM164500v1/GCA_001645005.1_ASM164500v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_caries-ASM164500v1/GCA_001645005.1_ASM164500v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_caries-ASM164500v1/GCA_001645005.1_ASM164500v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_caries-ASM164500v1/GCA_001645005.1_ASM164500v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:19:56 2019 # [ok]